2
34
0
http://purl.obolibrary.org/obo/DIDEO_00000059
evidence information from transport protein identification experiment
'evidence information from transport protein identification experiment' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some
('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some http://purl.obolibrary.org/obo/OBI_0001211)) and (http://purl.obolibrary.org/obo/OBI_0000293 some
('chemical substance' and ('is_specified_output_of' some
(http://purl.obolibrary.org/obo/GO_0098739 and ('has participant' some 'protein') and ('has participant' some
('chemical substance' and ('part of' some 'drug product')))))))))
http://purl.obolibrary.org/obo/DIDEO_00000060
evidence information from transport protein inhibition experiment
'evidence information from transport protein inhibition experiment' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some
('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some http://purl.obolibrary.org/obo/OBI_0001211)) and (http://purl.obolibrary.org/obo/OBI_0000293 some
('chemical substance' and ('is_specified_output_of' some
(http://purl.obolibrary.org/obo/GO_0032410 and ('has participant' some 'protein') and ('has participant' some
('chemical substance' and ('part of' some 'drug product')))))))))
http://purl.obolibrary.org/obo/GO_0098657
import into cell
'import into cell' SubClassOf 'transport'
http://purl.obolibrary.org/obo/DIDEO_00000104
evidence information from p-glycoprotein transport protein identification experiment
'evidence information from p-glycoprotein transport protein identification experiment' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some
('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some
('chemical substance' and ('is_specified_output_of' some
('import across plasma membrane' and ('has participant' some 'multidrug resistance protein 1') and ('has participant' some
('chemical substance' and ('part of' some 'drug product')))))))))
'evidence information from p-glycoprotein transport protein identification experiment' SubClassOf 'evidence information content entity'
http://purl.obolibrary.org/obo/DIDEO_00000105
evidence information from p-glycoprotein transport protein identification experiment using Caco 2 cell lines
'evidence information from p-glycoprotein transport protein identification experiment using Caco 2 cell lines' SubClassOf 'evidence information content entity'
'evidence information from p-glycoprotein transport protein identification experiment using Caco 2 cell lines' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some
('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some 'Caco-2 cell') and (http://purl.obolibrary.org/obo/OBI_0000293 some
('chemical substance' and ('is_specified_output_of' some
('import across plasma membrane' and ('has participant' some 'multidrug resistance protein 1') and ('has participant' some
('chemical substance' and ('part of' some 'drug product')))))))))
http://purl.obolibrary.org/obo/DIDEO_00000106
evidence information from p-glycoprotein transport protein identification experiment using overexpressed cell lines
'evidence information from p-glycoprotein transport protein identification experiment using overexpressed cell lines' SubClassOf 'evidence information content entity'
'evidence information from p-glycoprotein transport protein identification experiment using overexpressed cell lines' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some
('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some
('chemical substance' and ('is_specified_output_of' some
('import across plasma membrane' and ('has participant' some 'multidrug resistance protein 1') and ('has participant' some
('chemical substance' and ('part of' some 'drug product'))))))) and (http://purl.obolibrary.org/obo/OBI_0000293 some
('cell line cell' and ('participates in' some 'overexpression')))))
http://purl.obolibrary.org/obo/DIDEO_00000107
evidence information from OATP1B1 transport protein identification experiment
'evidence information from OATP1B1 transport protein identification experiment' SubClassOf 'evidence information content entity'
'evidence information from OATP1B1 transport protein identification experiment' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some
('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some
('chemical substance' and ('is_specified_output_of' some
('import across plasma membrane' and ('has participant' some 'solute carrier organic anion transporter family member 1B1') and ('has participant' some
('chemical substance' and ('part of' some 'drug product')))))))))
http://purl.obolibrary.org/obo/CLO_0000001
cell line cell
'cell line cell' SubClassOf 'cultured cell'
http://purl.obolibrary.org/obo/DIDEO_00000110
evidence information from OATP1B3 transport protein identification experiment using overexpressed cell lines
'evidence information from OATP1B3 transport protein identification experiment using overexpressed cell lines' SubClassOf 'evidence information content entity'
'evidence information from OATP1B3 transport protein identification experiment using overexpressed cell lines' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some
('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some
('chemical substance' and ('is_specified_output_of' some
('import across plasma membrane' and ('has participant' some 'solute carrier organic anion transporter family member 1B3') and ('has participant' some
('chemical substance' and ('part of' some 'drug product'))))))) and (http://purl.obolibrary.org/obo/OBI_0000293 some
('cell line cell' and ('participates in' some 'overexpression')))))
http://purl.obolibrary.org/obo/DIDEO_00000115
evidence information from OATP1B1 inhibition experiment using overexpressed cell lines
'evidence information from OATP1B1 inhibition experiment using overexpressed cell lines' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some
('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some
('chemical substance' and ('is_specified_output_of' some
('negative regulation of transporter activity' and ('has participant' some 'solute carrier organic anion transporter family member 1B1') and ('has participant' some
('chemical substance' and ('part of' some 'drug product'))))))) and (http://purl.obolibrary.org/obo/OBI_0000293 some
('cell line cell' and ('participates in' some 'overexpression')))))
'evidence information from OATP1B1 inhibition experiment using overexpressed cell lines' SubClassOf 'evidence information content entity'
http://purl.obolibrary.org/obo/DIDEO_00000116
evidence information from OATP1B3 inhibition experiment using overexpressed cell lines
'evidence information from OATP1B3 inhibition experiment using overexpressed cell lines' SubClassOf 'evidence information content entity'
'evidence information from OATP1B3 inhibition experiment using overexpressed cell lines' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some
('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some
('chemical substance' and ('is_specified_output_of' some
('negative regulation of transporter activity' and ('has participant' some 'solute carrier organic anion transporter family member 1B3') and ('has participant' some
('chemical substance' and ('part of' some 'drug product'))))))) and (http://purl.obolibrary.org/obo/OBI_0000293 some
('cell line cell' and ('participates in' some 'overexpression')))))
http://purl.obolibrary.org/obo/DIDEO_00000117
evidence information from OATP1B3 inhibition experiment
'evidence information from OATP1B3 inhibition experiment' SubClassOf 'evidence information content entity'
'evidence information from OATP1B3 inhibition experiment' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some
('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some
('chemical substance' and ('is_specified_output_of' some
('negative regulation of transporter activity' and ('has participant' some 'solute carrier organic anion transporter family member 1B3') and ('has participant' some
('chemical substance' and ('part of' some 'drug product')))))))))
http://purl.obolibrary.org/obo/DIDEO_00000111
evidence information from p-glycoprotein inhibition experiment
'evidence information from p-glycoprotein inhibition experiment' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some
('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some
('chemical substance' and ('is_specified_output_of' some
('negative regulation of transporter activity' and ('has participant' some 'multidrug resistance protein 1') and ('has participant' some
('chemical substance' and ('part of' some 'drug product')))))))))
'evidence information from p-glycoprotein inhibition experiment' SubClassOf 'evidence information content entity'
http://purl.obolibrary.org/obo/DIDEO_00000112
evidence information from p-glycoprotein inhibition experiment using Caco 2 cell lines
'evidence information from p-glycoprotein inhibition experiment using Caco 2 cell lines' SubClassOf 'evidence information content entity'
'evidence information from p-glycoprotein inhibition experiment using Caco 2 cell lines' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some
('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some 'Caco-2 cell') and (http://purl.obolibrary.org/obo/OBI_0000293 some
('chemical substance' and ('is_specified_output_of' some
('negative regulation of transporter activity' and ('has participant' some 'multidrug resistance protein 1') and ('has participant' some
('chemical substance' and ('part of' some 'drug product')))))))))
http://purl.obolibrary.org/obo/DIDEO_00000113
evidence information from p-glycoprotein inhibition experiment using overexpressed cell lines
'evidence information from p-glycoprotein inhibition experiment using overexpressed cell lines' SubClassOf 'evidence information content entity'
'evidence information from p-glycoprotein inhibition experiment using overexpressed cell lines' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some
('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some
('chemical substance' and ('is_specified_output_of' some
('negative regulation of transporter activity' and ('has participant' some 'multidrug resistance protein 1') and ('has participant' some
('chemical substance' and ('part of' some 'drug product'))))))) and (http://purl.obolibrary.org/obo/OBI_0000293 some
('cell line cell' and ('participates in' some 'overexpression')))))
http://purl.obolibrary.org/obo/DIDEO_00000114
evidence information from OATP1B1 inhibition experiment
'evidence information from OATP1B1 inhibition experiment' SubClassOf 'evidence information content entity'
'evidence information from OATP1B1 inhibition experiment' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some
('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some
('chemical substance' and ('is_specified_output_of' some
('negative regulation of transporter activity' and ('has participant' some 'solute carrier organic anion transporter family member 1B1') and ('has participant' some
('chemical substance' and ('part of' some 'drug product')))))))))
http://purl.obolibrary.org/obo/DIDEO_00000108
evidence information from OATP1B3 transport protein identification experiment
'evidence information from OATP1B3 transport protein identification experiment' SubClassOf 'evidence information content entity'
'evidence information from OATP1B3 transport protein identification experiment' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some
('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some
('chemical substance' and ('is_specified_output_of' some
('import across plasma membrane' and ('has participant' some 'solute carrier organic anion transporter family member 1B3') and ('has participant' some
('chemical substance' and ('part of' some 'drug product')))))))))
http://purl.obolibrary.org/obo/DIDEO_00000109
evidence information from OATP1B1 transport protein identification experiment using overexpressed cell lines
'evidence information from OATP1B1 transport protein identification experiment using overexpressed cell lines' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some
('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some
('chemical substance' and ('is_specified_output_of' some
('import across plasma membrane' and ('has participant' some 'solute carrier organic anion transporter family member 1B1') and ('has participant' some
('chemical substance' and ('part of' some 'drug product'))))))) and (http://purl.obolibrary.org/obo/OBI_0000293 some
('cell line cell' and ('participates in' some 'overexpression')))))
'evidence information from OATP1B1 transport protein identification experiment using overexpressed cell lines' SubClassOf 'evidence information content entity'
http://purl.obolibrary.org/obo/GO_0051234
establishment of localization
'establishment of localization' SubClassOf 'localization'
http://purl.obolibrary.org/obo/GO_0098739
import across plasma membrane
'import across plasma membrane' SubClassOf 'import into cell'
http://purl.obolibrary.org/obo/INO_0000102
gene expression
'gene expression' SubClassOf 'biological_process'
http://purl.obolibrary.org/obo/INO_0000114
overexpression
'overexpression' SubClassOf 'gene expression'
http://purl.obolibrary.org/obo/GO_0032879
regulation of localization
'regulation of localization' SubClassOf 'regulation of biological process'
http://purl.obolibrary.org/obo/GO_0051049
regulation of transport
'regulation of transport' SubClassOf 'regulation of localization'
http://purl.obolibrary.org/obo/CL_0000578
experimentally modified cell in vitro
'experimentally modified cell in vitro' SubClassOf 'processed material'
http://purl.obolibrary.org/obo/CLO_0002172
Caco-2 cell
'Caco-2 cell' SubClassOf 'cell line cell'
http://purl.obolibrary.org/obo/GO_0051051
negative regulation of transport
'negative regulation of transport' SubClassOf 'regulation of transport'
http://purl.obolibrary.org/obo/GO_0006810
transport
'transport' SubClassOf 'establishment of localization'
http://purl.obolibrary.org/obo/GO_0032409
regulation of transporter activity
'regulation of transporter activity' SubClassOf 'regulation of transport'
http://purl.obolibrary.org/obo/OBI_0001211
ex vivo design
'ex vivo design' SubClassOf 'study design'
http://purl.obolibrary.org/obo/PR_000015224
solute carrier organic anion transporter family member 1B3
'solute carrier organic anion transporter family member 1B3' SubClassOf 'protein'
http://purl.obolibrary.org/obo/PR_000015223
solute carrier organic anion transporter family member 1B1
'solute carrier organic anion transporter family member 1B1' SubClassOf 'protein'
http://purl.obolibrary.org/obo/GO_0032410
negative regulation of transporter activity
'negative regulation of transporter activity' SubClassOf 'regulation of transporter activity'
http://purl.obolibrary.org/obo/CL_0000010
cultured cell
'cultured cell' SubClassOf 'experimentally modified cell in vitro'
http://purl.obolibrary.org/obo/GO_0051179
localization
'localization' SubClassOf 'biological_process'
http://purl.obolibrary.org/obo/PR_000001891
multidrug resistance protein 1
'multidrug resistance protein 1' SubClassOf 'protein'