format-version: 1.2 data-version: 2014-09-23 date: 16:09:2014 13:31 saved-by: mmc46 auto-generated-by: OBO-Edit 2.3 subsetdef: abnormal_slim "Abnormal/normal slim" subsetdef: absent_slim "Absent/present slim" subsetdef: attribute_slim "Attribute slim" subsetdef: camcur "" subsetdef: camcur "camcur" subsetdef: cell_quality "cell_quality" subsetdef: cur "cur" subsetdef: deprecated "warning of impending obsoletion" subsetdef: EmbDevSlim "EmbDevSlim" subsetdef: FlyTed "Testis slim" subsetdef: FT_new "FlyTed temp subset for edit tracking purposes" subsetdef: larval_OF "larval olfactory system" subsetdef: RD "terms for rd test ontology" subsetdef: relational_slim "Relational slim: types of quality that require an additional entity in order to exist" subsetdef: value_slim "Value slim" synonymtypedef: BRAIN_NAME_ABV "BrainName official abbreviation" synonymtypedef: BRAND_NAME "BRAND NAME" synonymtypedef: FORMULA "FORMULA" synonymtypedef: InChI "InChI" synonymtypedef: InChIKey "InChIKey" synonymtypedef: INN "INN" synonymtypedef: IUPAC_NAME "IUPAC NAME" synonymtypedef: SMILES "SMILES" synonymtypedef: systematic_synonym "Systematic synonym" EXACT default-namespace: FlyBase miscellaneous CV remark: Imports terms from CHEBI - datestamp = 02:12:2011 01:47 ontology: fbcv owl-axioms: Prefix(owl:=)\nPrefix(rdf:=)\nPrefix(xml:=)\nPrefix(xsd:=)\nPrefix(rdfs:=)\n\n\nOntology(\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:maxExclusive \"50\"^^xsd:integer xsd:minInclusive \"5\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"98\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"50\"^^xsd:integer xsd:maxExclusive \"98\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"5\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"98\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"98\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"98\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"98\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"5\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"98\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"98\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"98\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"98\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"98\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"50\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"50\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"50\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"50\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"50\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"5\"^^xsd:integer xsd:maxExclusive \"98\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"5\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"5\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"5\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"5\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"5\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"5\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"98\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"98\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"98\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"98\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"98\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"98\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"98\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"50\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"50\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"50\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"50\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"5\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"5\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"5\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"5\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"98\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"50\"^^xsd:integer)))\nSubClassOf( DataSomeValuesFrom( DatatypeRestriction(xsd:short xsd:minInclusive \"5\"^^xsd:integer)))\nDataPropertyDomain( )\nDataPropertyRange( DatatypeRestriction(xsd:short xsd:maxInclusive \"100\"^^xsd:integer xsd:minInclusive \"0\"^^xsd:integer))\n) [Term] id: FBcv:0000000 name: FlyBase CV [Term] id: FBcv:0000001 name: death certificate namespace: pub_type comment: This term was obsoleted because it was only ever used to annotate one publication: A copy of Calvin Bridges death certificate. This can still be found in the Drosophila offprint collection (FBrf0186653). subset: camcur is_obsolete: true [Term] id: FBcv:0000002 name: thermotaxis behavior defective namespace: phenotypic_class def: "Phenotype that is a defect in thermotaxis (GO:0043052). 'thermotaxis' is defined as: 'The directed movement of a motile cell or organism in response to a temperature gradient. Movement may be towards either a higher or lower temperature.'" [FBC:DOS, GOC:cab1, WB_REF:cgc467] subset: camcur synonym: "thermotaxis behaviour defective" EXACT [] is_a: FBcv:0000683 ! temperature response defective [Term] id: FBcv:0000003 name: In transgenic Drosophila (intraspecific) namespace: mode_of_assay subset: camcur xref: abbrev:1 is_a: FBcv:0000607 ! In transgenic Drosophila [Term] id: FBcv:0000004 name: Whole-organism transient assay (intraspecific) namespace: mode_of_assay subset: camcur xref: abbrev:2 is_a: FBcv:0000608 ! Whole-organism transient assay [Term] id: FBcv:0000005 name: qualifier is_a: FBcv:0000000 ! FlyBase CV [Term] id: FBcv:0000006 name: male semi-fertile namespace: phenotypic_class subset: camcur is_a: FBcv:0000375 ! semi-fertile is_a: FBcv:0000376 ! male fertile [Term] id: FBcv:0000007 name: female semi-fertile namespace: phenotypic_class subset: camcur is_a: FBcv:0000375 ! semi-fertile is_a: FBcv:0000377 ! female fertile [Term] id: FBcv:0000008 name: modifier of variegation namespace: phenotypic_class def: "Genotype g1 is a modifier of variegation if, and only if, some genotype g2 has a variegated phenotype and the degree of variegation caused by g1g2 is significantly different from that caused by g2 alone." [FBC:DOS] subset: camcur synonym: "variegation" RELATED [FBC:DOS] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000009 name: temporal stage qualifier namespace: temporal_qualifier xref: PATO:0000083 is_a: FBcv:0000176 ! temporal qualifier [Term] id: FBcv:0000010 name: monophasic namespace: temporal_qualifier comment: Deprecated: Use of this term is discouraged as there is no way to decide how to group anatomy terms combined with this qualifier with other terms in the anatomy ontology. Subject to discussion and once its usage in old curation is removed, this term will be obsoleted. DS xref: PATO:0001773 is_a: FBcv:0000009 ! temporal stage qualifier [Term] id: FBcv:0000011 name: relative temporal qualifier namespace: temporal_qualifier is_a: FBcv:0000176 ! temporal qualifier [Term] id: FBcv:0000012 name: absolute temporal qualifier namespace: temporal_qualifier xref: PATO:0000165 is_a: FBcv:0000176 ! temporal qualifier [Term] id: FBcv:0000013 name: descriptor is_a: FBcv:0000000 ! FlyBase CV [Term] id: FBcv:0000014 name: structural qualifier namespace: structural_qualifier is_a: FBcv:0000809 ! phenotype qualifier [Term] id: FBcv:0000015 name: postage stamp namespace: pub_type comment: This term was obsoleted because it was little used. subset: camcur is_obsolete: true [Term] id: FBcv:0000016 name: Baylor TE recombination mapping kit stock comment: Consider - FBsv:0000605. is_obsolete: true [Term] id: FBcv:0000017 name: penetrance qualifier def: "Penetrance is the fraction of individuals of a given genotype who exhibit the phenotype associated with that genotype." [ISBN:978-0-7167-3520-5] is_obsolete: true [Term] id: FBcv:0000018 name: penetrance complete def: "Penetrance is the fraction of individuals of a given genotype who exhibit the phenotype associated with that genotype. Penetrance is complete when all the individuals of a given genotype exhibit the phenotype associated with that genotype." [ISBN:978-0-7167-3520-5] is_obsolete: true [Term] id: FBcv:0000019 name: penetrance incomplete def: "Penetrance is the fraction of individuals of a given genotype who exhibit the phenotype associated with that genotype. Penetrance is incomplete when only some the individuals of a given genotype exhibit the phenotype associated with that genotype." [ISBN:978-0-7167-3520-5] is_obsolete: true [Term] id: FBcv:0000020 name: penetrance percent def: "Penetrance is the fraction of individuals of a given genotype who exhibit the phenotype associated with that genotype. Penetrance is incomplete when only a percentage of the individuals of a given genotype exhibit the phenotype associated with that genotype." [ISBN:978-0-7167-3520-5] comment: This term should be modified by a % value. This is not currently possible in FlyBase curation. is_obsolete: true [Term] id: FBcv:0000021 name: expressivity qualifier def: "Expressivity measures the extent to which a given genotype is expressed at the phenotypic level." [ISBN:978-0-7167-3520-5] is_obsolete: true [Term] id: FBcv:0000022 name: expressivity complete def: "Expressivity measures the extent to which a given genotype is expressed at the phenotypic level. Expressivity is complete when an individual of a given genotype expresses the full phenotype associated with that genotype." [ISBN:978-0-7167-3520-5] is_obsolete: true [Term] id: FBcv:0000023 name: expressivity incomplete def: "Expressivity measures the extent to which a given genotype is expressed at the phenotypic level. Expressivity is incomplete when an individual of a given genotype expresses only partially the phenotype associated with that genotype." [ISBN:978-0-7167-3520-5] is_obsolete: true [Term] id: FBcv:0000024 name: expressivity high def: "Expressivity measures the extent to which a given genotype is expressed at the phenotypic level. \"High expressivity\" conveys that while expressivity is not complete, the phenotype expressed is approaching that of complete expressivity." [ISBN:978-0-7167-3520-5] is_obsolete: true [Term] id: FBcv:0000025 name: expressivity low def: "Expressivity measures the extent to which a given genotype is expressed at the phenotypic level. \"Low expressivity\" conveys that phenotype expressed is a much reduced version compared to complete expressivity." [ISBN:978-0-7167-3520-5] is_obsolete: true [Term] id: FBcv:0000026 name: recessive visible allele recombination mapping stock is_obsolete: true [Term] id: FBcv:0000027 name: dominant visible allele recombination mapping stock is_obsolete: true [Term] id: FBcv:0000028 name: SNP recombination mapping stock comment: Consider - FBsv:0001018. is_obsolete: true [Term] id: FBcv:0000029 name: transposable element mutagenesis stock is_obsolete: true [Term] id: FBcv:0000030 name: compartment namespace: spatial_qualifier comment: DEPRECATION WARNING: This term is marked for obsoletion. If possible, please use 'developmental compartment' (FBbt:00007110) or one of its subclasses instead. is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000031 name: anterior compartment namespace: spatial_qualifier def: "Restricted to the anterior compartment of some specified type." [FBC:DS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. DEPRECATION WARNING: This term is marked for obsoletion. If possible, please use 'developmental compartment' (FBbt:00007110) or one of its subclasses instead. subset: camcur is_a: FBcv:0000030 ! compartment [Term] id: FBcv:0000032 name: compartment boundary namespace: spatial_qualifier def: "Restricted to some compartment boundary within a specified type." [FBC:DS] comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. Will soon be replaced by a set of more specific anatomy terms. subset: camcur subset: deprecated is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000033 name: anterior/posterior compartment boundary namespace: spatial_qualifier def: "Restricted to an anterior/posterior compartment boundary within a specified type." [FBC:DS] comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. Will soon be replaced by a set of more specific anatomy terms. subset: camcur subset: deprecated is_a: FBcv:0000032 ! compartment boundary [Term] id: FBcv:0000034 name: dorsal/ventral compartment boundary namespace: spatial_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. Will soon be replaced by a set of more specific anatomy terms. subset: camcur subset: deprecated is_a: FBcv:0000032 ! compartment boundary [Term] id: FBcv:0000035 name: dorsal compartment namespace: spatial_qualifier def: "Restricted to the dorsal compartment of some specified type." [FBC:DS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. DEPRECATION WARNING: This term is marked for obsoletion. If possible, please use 'developmental compartment' (FBbt:00007110) or one of its subclasses instead. subset: camcur is_a: FBcv:0000030 ! compartment [Term] id: FBcv:0000036 name: posterior compartment namespace: spatial_qualifier def: "Restricted to the posterior compartment of some specified type." [FBC:DS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. DEPRECATION WARNING: This term is marked for obsoletion. If possible, please use 'developmental compartment' (FBbt:00007110) or one of its subclasses instead. subset: camcur is_a: FBcv:0000030 ! compartment [Term] id: FBcv:0000037 name: ventral compartment namespace: spatial_qualifier def: "Restricted to the ventral compartment of some specified type." [FBC:DS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. DEPRECATION WARNING: This term is marked for obsoletion. If possible, please use 'developmental compartment' (FBbt:00007110) or one of its subclasses instead. subset: camcur is_a: FBcv:0000030 ! compartment [Term] id: FBcv:0000038 name: relative spatial qualifier namespace: spatial_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. xref: PATO:0001631 is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000039 name: anterior to namespace: spatial_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q.\n\nDeprecated: Use of this term is discouraged as there is no way to decide how to group anatomy terms combined with this qualifier with other terms in the anatomy ontology. Once its usage in old curation is removed, this term will be obsoleted. DS xref: PATO:0001632 is_a: FBcv:0000038 ! relative spatial qualifier [Term] id: FBcv:0000040 name: distal to namespace: spatial_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q.\n\nDeprecated: Use of this term is discouraged as there is no way to decide how to group anatomy terms combined with this qualifier with other terms in the anatomy ontology. Once its usage in old curation is removed, this term will be obsoleted. DS xref: PATO:0001234 is_a: FBcv:0000038 ! relative spatial qualifier [Term] id: FBcv:0000041 name: dorsal to namespace: spatial_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q.\n\nDeprecated: Use of this term is discouraged as there is no way to decide how to group anatomy terms combined with this qualifier with other terms in the anatomy ontology. Once its usage in old curation is removed, this term will be obsoleted. DS xref: PATO:0001233 is_a: FBcv:0000038 ! relative spatial qualifier [Term] id: FBcv:0000042 name: deficiency kit stock synonym: "deletion kit stock" RELATED [] is_obsolete: true [Term] id: FBcv:0000043 name: transposase source for transposable element mutagenesis comment: Consider - FBsv:0001020. is_obsolete: true [Term] id: FBcv:0000044 name: ammunition source for transposable element mutagenesis comment: Consider - FBsv:0001022. is_obsolete: true [Term] id: FBcv:0000045 name: posterior to namespace: spatial_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q.\n\nDeprecated: Use of this term is discouraged as there is no way to decide how to group anatomy terms combined with this qualifier with other terms in the anatomy ontology. Once its usage in old curation is removed, this term will be obsoleted. DS xref: PATO:0001633 is_a: FBcv:0000038 ! relative spatial qualifier [Term] id: FBcv:0000046 name: precursor namespace: temporal_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q.\n\nDeprecated: Use of this term is discouraged as there is no way to decide how to group anatomy terms combined with this qualifier with other terms in the anatomy ontology. Once its usage in old curation is removed, this term will be obsoleted. DS is_a: FBcv:0000176 ! temporal qualifier [Term] id: FBcv:0000047 name: proximal to namespace: spatial_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q.\n\nDeprecated: Use of this term is discouraged as there is no way to decide how to group anatomy terms combined with this qualifier with other terms in the anatomy ontology. Once its usage in old curation is removed, this term will be obsoleted. DS xref: PATO:0001195 is_a: FBcv:0000038 ! relative spatial qualifier [Term] id: FBcv:0000048 name: surrounding namespace: spatial_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q.\n\nDeprecated: Use of this term is discouraged as there is no way to decide how to group anatomy terms combined with this qualifier with other terms in the anatomy ontology. Once its usage in old curation is removed, this term will be obsoleted. DS xref: PATO:0001772 is_a: FBcv:0000038 ! relative spatial qualifier [Term] id: FBcv:0000049 name: ventral to namespace: spatial_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q.\n\nDeprecated: Use of this term is discouraged as there is no way to decide how to group anatomy terms combined with this qualifier with other terms in the anatomy ontology. Once its usage in old curation is removed, this term will be obsoleted. DS xref: PATO:0001196 is_a: FBcv:0000038 ! relative spatial qualifier [Term] id: FBcv:0000050 name: vicinity of namespace: spatial_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q.\n\nDeprecated: Use of this term is discouraged as there is no way to decide how to group anatomy terms combined with this qualifier with other terms in the anatomy ontology. Once its usage in old curation is removed, this term will be obsoleted. DS xref: PATO:0001771 is_a: FBcv:0000038 ! relative spatial qualifier [Term] id: FBcv:0000051 name: segment boundary namespace: spatial_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000052 name: spatial qualifier namespace: spatial_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. is_a: FBcv:0000005 ! qualifier [Term] id: FBcv:0000053 name: anterior namespace: spatial_qualifier def: "Restricted to anterior region of some specified type." [FBC:DS] comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000054 name: apical namespace: spatial_qualifier def: "Restricted to apical region of some specified type." [FBC:DS] comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAP6-q. Proforma field: GAT23-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000055 name: basal namespace: spatial_qualifier def: "Restricted to basal region of some specified type." [FBC:DS] comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAP6-q. Proforma field: GAT23-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000056 name: central namespace: spatial_qualifier def: "Restricted to central region of some specified type." [FBC:DS] comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000057 name: contralateral namespace: spatial_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q.\n\nDeprecated: Contralateral means - on the opposite side from .... In curation usage: on the opposite side from what ? Will be obsoleted once a replacement term agreed upon (if needed) and any old usage retrofitted. DS is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000058 name: distal namespace: spatial_qualifier def: "Restricted to distal region of some specified type." [FBC:DS] comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000059 name: dorsal namespace: spatial_qualifier def: "Restricted to dorsal region of some specified type." [FBC:DS] comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000060 name: dorso-lateral namespace: spatial_qualifier def: "Restricted to dorso-lateral region of some specified type." [FBC:DS] comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000061 name: ectopic namespace: structural_qualifier def: "When, compared to wild-type, an extra copy of an anatomical structure is present in an abnormal location, then this structure is ectopic." [FBC:DOS] comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. An extra copy of an anatomical structure that is present in the same location as in wild-type is supernumerary, rather than ectopic. subset: camcur is_a: FBcv:0000014 ! structural qualifier [Term] id: FBcv:0000062 name: ipsilateral namespace: spatial_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q.\n\nDeprecated: As far as I can tell, ipsilateral means - on the same side as .... In curation usage: on the same side as what ? Will be obsoleted once a replacement term agreed upon (if needed) and any old usage retrofitted. DS is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000063 name: lateral namespace: spatial_qualifier def: "Restricted to lateral region(s) of some specified type." [FBC:DS] comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAP6-q. Proforma field: GAT23-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000064 name: medial namespace: spatial_qualifier def: "Restricted to medial region of some specified type." [FBC:DS] comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000065 name: posterior namespace: spatial_qualifier def: "Restricted to posterior region of some specified type." [FBC:DS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000066 name: proximal namespace: spatial_qualifier def: "Restricted to proximal region of some specified type." [FBC:DS] comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000067 name: restricted namespace: spatial_qualifier def: "Restricted to unknown part(s) of a specified type." [FBC:DS] comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000068 name: supernumerary namespace: structural_qualifier def: "Present in the correct location but in larger numbers than in wild-type." [FBC:DOS] comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000014 ! structural qualifier [Term] id: FBcv:0000069 name: ubiquitous namespace: spatial_qualifier def: "Expressed everywhere at some specified stage." [FBC:DOS] comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000070 name: ventral namespace: spatial_qualifier def: "Restricted to ventral region of some specified type." [FBC:DS] comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000071 name: ventro-lateral namespace: spatial_qualifier def: "Restricted to ventro-lateral region of some specified type." [FBC:DS] comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000072 name: gene expression qualifier is_obsolete: true [Term] id: FBcv:0000073 name: embryonic expression pattern comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. is_obsolete: true [Term] id: FBcv:0000074 name: egg length namespace: spatial_qualifier def: "Position in the egg or pre-gastrula embryo expressed as a percentage of egg length, where 0% corresponds to the posterior tip and 100% to the anterior tip." [FBC:DOS] is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000075 name: 0% egg length namespace: spatial_qualifier def: "At the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000076 name: 0-10% egg length namespace: spatial_qualifier def: "0-10% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000077 name: 0-100% egg length namespace: spatial_qualifier def: "The full length of the pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000078 name: 0-20% egg length namespace: spatial_qualifier def: "0-20% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000079 name: 0-30% egg length namespace: spatial_qualifier def: "0-30% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000080 name: 0-40% egg length namespace: spatial_qualifier def: "0-40% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000081 name: 0-50% egg length namespace: spatial_qualifier def: "0-50% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000082 name: 0-60% egg length namespace: spatial_qualifier def: "0-60% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000083 name: 0-70% egg length namespace: spatial_qualifier def: "0-70% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000084 name: 0-80% egg length namespace: spatial_qualifier def: "0-80% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000085 name: 0-90% egg length namespace: spatial_qualifier def: "0-90% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000086 name: 10% egg length namespace: spatial_qualifier def: "10% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000087 name: 10-100% egg length namespace: spatial_qualifier def: "10-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000088 name: 10-20% egg length namespace: spatial_qualifier def: "10-20% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000089 name: 10-30% egg length namespace: spatial_qualifier def: "10-30% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000090 name: 10-40% egg length namespace: spatial_qualifier def: "10-40% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000091 name: 10-50% egg length namespace: spatial_qualifier def: "10-50% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000092 name: 10-60% egg length namespace: spatial_qualifier def: "10-60% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000093 name: 10-70% egg length namespace: spatial_qualifier def: "10-70% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000094 name: 10-80% egg length namespace: spatial_qualifier def: "10-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000095 name: 10-90% egg length namespace: spatial_qualifier def: "10-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000096 name: 100% egg length namespace: spatial_qualifier def: "At the anterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000097 name: 20% egg length namespace: spatial_qualifier def: "10% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000098 name: 20-100% egg length namespace: spatial_qualifier def: "20-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000099 name: 20-30% egg length namespace: spatial_qualifier def: "20-30% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000100 name: 20-40% egg length namespace: spatial_qualifier def: "20-40% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000101 name: 20-50% egg length namespace: spatial_qualifier def: "20-50% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000102 name: 20-60% egg length namespace: spatial_qualifier def: "20-60% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000103 name: 20-70% egg length namespace: spatial_qualifier def: "20-70% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000104 name: 20-80% egg length namespace: spatial_qualifier def: "20-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000105 name: 20-90% egg length namespace: spatial_qualifier def: "20-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000106 name: 30% egg length namespace: spatial_qualifier def: "30% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000107 name: 30-100% egg length namespace: spatial_qualifier def: "30-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000108 name: 30-40% egg length namespace: spatial_qualifier def: "30-40% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000109 name: 30-50% egg length namespace: spatial_qualifier def: "30-50% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000110 name: 30-60% egg length namespace: spatial_qualifier def: "30-60% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000111 name: 30-70% egg length namespace: spatial_qualifier def: "30-70% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000112 name: 30-80% egg length namespace: spatial_qualifier def: "30-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000113 name: 30-90% egg length namespace: spatial_qualifier def: "30-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000114 name: 40% egg length namespace: spatial_qualifier def: "40% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000115 name: 40-100% egg length namespace: spatial_qualifier def: "40-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000116 name: 40-50% egg length namespace: spatial_qualifier def: "40-50% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000117 name: 40-60% egg length namespace: spatial_qualifier def: "40-60% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000118 name: 40-70% egg length namespace: spatial_qualifier def: "40-70% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000119 name: 40-80% egg length namespace: spatial_qualifier def: "40-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000120 name: 40-90% egg length namespace: spatial_qualifier def: "40-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000121 name: 50% egg length namespace: spatial_qualifier def: "50% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000122 name: 50-100% egg length namespace: spatial_qualifier def: "50-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000123 name: 50-60% egg length namespace: spatial_qualifier def: "50-60% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000124 name: 50-70% egg length namespace: spatial_qualifier def: "50-70% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000125 name: 50-80% egg length namespace: spatial_qualifier def: "50-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000126 name: 50-90% egg length namespace: spatial_qualifier def: "50-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000127 name: 60% egg length namespace: spatial_qualifier def: "60% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000128 name: 60-100% egg length namespace: spatial_qualifier def: "60-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000129 name: 60-80% egg length namespace: spatial_qualifier def: "60-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000130 name: 60-90% egg length namespace: spatial_qualifier def: "60-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000131 name: 70% egg length namespace: spatial_qualifier def: "70% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000132 name: 70-100% egg length namespace: spatial_qualifier def: "70-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000133 name: 70-80% egg length namespace: spatial_qualifier def: "70-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000134 name: 70-90% egg length namespace: spatial_qualifier def: "70-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000135 name: 80% egg length namespace: spatial_qualifier def: "80% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000136 name: 80-90% egg length namespace: spatial_qualifier def: "80-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000137 name: 90% egg length namespace: spatial_qualifier def: "90% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000139 name: 90-100% egg length namespace: spatial_qualifier alt_id: FBcv:0000138 def: "90-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] synonym: "90-100% egg length" RELATED [] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000140 name: FlyBase analysis namespace: pub_type def: "A record of an analysis carried out by FlyBase that has not been formally published." [FBC:SM] subset: camcur is_a: FBcv:0000233 ! unpublished [Term] id: FBcv:0000141 name: gradient namespace: spatial_qualifier is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000142 name: anterior posterior gradient namespace: spatial_qualifier is_a: FBcv:0000141 ! gradient [Term] id: FBcv:0000143 name: dorsal ventral gradient namespace: spatial_qualifier is_a: FBcv:0000141 ! gradient [Term] id: FBcv:0000144 name: maternal pattern comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. is_obsolete: true [Term] id: FBcv:0000145 name: striped namespace: spatial_qualifier def: "Restricted to stripes in some specified type" [FBC:DS] comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000146 name: I-CreI namespace: origin_of_mutation def: "Sequence change caused by the cleavage of a 19-24 bp palindromic DNA site by the I-CreI endonuclease." [UniProt:P05725] subset: camcur synonym: "change induced by I-CreI endonuclease cleavage" EXACT [] is_a: FBcv:0003007 ! site specific cleavage [Term] id: FBcv:0000147 name: even pair rule expression pattern namespace: embryonic_pattern_qualifier def: "Expression in even, but not odd numbered segment of the blastoderm." [FBC:DOS] is_a: FBcv:0000322 ! pair rule expression pattern [Term] id: FBcv:0000148 name: odd pair rule expression pattern namespace: embryonic_pattern_qualifier def: "Expression in odd, but not even numbered segments of the blastoderm." [FBC:DOS] is_a: FBcv:0000322 ! pair rule expression pattern [Term] id: FBcv:0000149 name: species list namespace: pub_type def: "A list of species found in a specified area." [FBC:SM] subset: camcur is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000150 name: segmentally repeated namespace: spatial_qualifier def: "Restricted to a segmentally repeated pattern with some specified type." [FBC:DOS] comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000151 name: archive namespace: pub_type comment: This term was obsoleted because there because there were no instances of its use to classify any artefact in FlyBase. subset: camcur is_obsolete: true [Term] id: FBcv:0000152 name: balancer stock def: "A stock with one or more chromosomes (balancers) that are used primarily for their ability to preserve a stock genotype without selection." [FBC:KM] comment: Consider - FBsv:0001001. is_obsolete: true [Term] id: FBcv:0000153 name: cell autonomous namespace: genotype_to_phenotype_relation def: "A phenotypic effect which is expressed in and limited to cells of the mutant genetic constitution under investigation is said to be cell autonomous." [FlyBase:FBrf0002379] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000797 ! cell autonomy qualifier [Term] id: FBcv:0000154 name: cell non-autonomous namespace: genotype_to_phenotype_relation def: "A phenotypic effect which is not expressed in/limited to cells of the mutant genetic constitution under investigation is said to be cell non-autonomous." [FlyBase:FBrf0002379] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000797 ! cell autonomy qualifier [Term] id: FBcv:0000155 name: single balancer is_a: FBcv:0000687 ! balancer descriptor [Term] id: FBcv:0000156 name: pair of homologous balancers is_obsolete: true [Term] id: FBcv:0000157 name: recessive lethal balancer is_obsolete: true [Term] id: FBcv:0000158 name: balancer for chromosome 1 comment: Consider - FBsv:0001006. is_obsolete: true [Term] id: FBcv:0000159 name: balancer for chromosome 2 comment: Consider - FBsv:0001007. is_obsolete: true [Term] id: FBcv:0000160 name: balancer for chromosome 3 comment: Consider - FBsv:0001008. is_obsolete: true [Term] id: FBcv:0000161 name: maternal effect namespace: genotype_to_phenotype_relation def: "A phenotypic attribute is described as showing a maternal effect when the phenotype of an individual is a manifestation of the genotype of the mother, rather than the genotype of the individual." [ISBN:978-0-7167-3520-5] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000685 ! parental effect [Term] id: FBcv:0000162 name: non-rescuable maternal effect namespace: genotype_to_phenotype_relation def: "A phenotypic attribute is described as showing a non-rescuable maternal effect (strict maternal effect) when the introduction of a wild-type copy of the responsible mutation from the father has no ameliorating effect on the maternal effect mutant phenotype." [FlyBase:FBrf0049894] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000161 ! maternal effect [Term] id: FBcv:0000163 name: rescuable maternal effect namespace: genotype_to_phenotype_relation def: "A phenotypic attribute is described as showing a rescuable maternal effect when the introduction of a wild-type copy of the responsible mutation from the father ameliorates the maternal effect mutant phenotype." [FlyBase:FBrf0049894] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000161 ! maternal effect [Term] id: FBcv:0000164 name: paternal effect namespace: genotype_to_phenotype_relation def: "A phenotypic attribute is described as showing a paternal effect when the phenotype of an individual is a manifestation of the genotype of the father, rather than the genotype of the individual." [FlyBase:FBrf0102738] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000685 ! parental effect [Term] id: FBcv:0000165 name: pair of balancers for chromosome 2 is_obsolete: true [Term] id: FBcv:0000166 name: morphological qualifier namespace: expression_qualifier is_a: FBcv:0000005 ! qualifier [Term] id: FBcv:0000167 name: faint namespace: expression_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. is_a: FBcv:0000166 ! morphological qualifier [Term] id: FBcv:0000168 name: granular namespace: expression_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. xref: PATO:0001759 is_a: FBcv:0000166 ! morphological qualifier [Term] id: FBcv:0000169 name: intense namespace: expression_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. xref: PATO:0000049 is_a: FBcv:0000166 ! morphological qualifier [Term] id: FBcv:0000170 name: punctate namespace: expression_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. xref: PATO:0001512 is_a: FBcv:0000166 ! morphological qualifier [Term] id: FBcv:0000171 name: uniform namespace: expression_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. xref: PATO:0000438 is_a: FBcv:0000166 ! morphological qualifier [Term] id: FBcv:0000172 name: variable namespace: expression_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. xref: PATO:0001227 is_a: FBcv:0000166 ! morphological qualifier [Term] id: FBcv:0000173 name: pair of balancers for chromosome 3 is_obsolete: true [Term] id: FBcv:0000174 name: dominant male sterile balancer comment: Consider - FBsv:0001012. is_obsolete: true [Term] id: FBcv:0000175 name: dominant female sterile balancer comment: Consider - FBsv:0001012. is_obsolete: true [Term] id: FBcv:0000176 name: temporal qualifier namespace: temporal_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. is_a: FBcv:0000005 ! qualifier [Term] id: FBcv:0000177 name: dominant female sterile balancer for chromosome 2 is_obsolete: true [Term] id: FBcv:0000178 name: early namespace: temporal_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q.\n\nDeprecated: Use of this term is discouraged as there is no way to decide how to group anatomy terms combined with this qualifier with other terms in the anatomy ontology. Subject to discussion and once its usage in old curation is removed, this term will be obsoleted. DS xref: PATO:0000694 is_a: FBcv:0000011 ! relative temporal qualifier [Term] id: FBcv:0000179 name: dominant female sterile balancer for chromosome 3 is_obsolete: true [Term] id: FBcv:0000180 name: dominant male sterile balancer for chromosome 2 is_obsolete: true [Term] id: FBcv:0000181 name: late namespace: temporal_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q.\n\nDeprecated: Use of this term is discouraged as there is no way to decide how to group anatomy terms combined with this qualifier with other terms in the anatomy ontology. Subject to discussion and once its usage in old curation is removed, this term will be obsoleted. DS xref: PATO:0000502 is_a: FBcv:0000011 ! relative temporal qualifier [Term] id: FBcv:0000182 name: mid namespace: temporal_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q.\n\nDeprecated: Use of this term is discouraged as there is no way to decide how to group anatomy terms combined with this qualifier with other terms in the anatomy ontology. Subject to discussion and once its usage in old curation is removed, this term will be obsoleted. DS is_a: FBcv:0000011 ! relative temporal qualifier [Term] id: FBcv:0000183 name: n day namespace: temporal_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q.\n\nDeprecated: Use of this term is discouraged as there is no way to decide how to group anatomy terms combined with this qualifier with other terms in the anatomy ontology. Subject to discussion and once its usage in old curation is removed, this term will be obsoleted. DS is_a: FBcv:0000012 ! absolute temporal qualifier [Term] id: FBcv:0000184 name: n hr namespace: temporal_qualifier comment: Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q.\n\nDeprecated: Use of this term is discouraged as there is no way to decide how to group anatomy terms combined with this qualifier with other terms in the anatomy ontology. Subject to discussion and once its usage in old curation is removed, this term will be obsoleted. DS is_a: FBcv:0000012 ! absolute temporal qualifier [Term] id: FBcv:0000185 name: dominant male sterile balancer for chromosome 3 is_obsolete: true [Term] id: FBcv:0000186 name: recessive lethal balancer for chromosome 1 is_obsolete: true [Term] id: FBcv:0000187 name: recessive lethal balancer for chromosome 2 is_obsolete: true [Term] id: FBcv:0000188 name: publication descriptor is_a: FBcv:0000013 ! descriptor [Term] id: FBcv:0000189 name: publication class namespace: pub_type def: "A publicly available document. It includes individual articles, such as research papers and reviews, and collections of articles, such as scientific journals." [FBC:DOS, FBC:SM] is_a: FBcv:0000188 ! publication descriptor [Term] id: FBcv:0000190 name: abstract namespace: pub_type def: "An individual abstract of a presentation at a meeting, congress, conference, symposium, colloquium, seminar, workshop, round table, or other professional gathering." [http://www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?view=expanded&field=uid&term=D016416] subset: camcur synonym: "Meeting Abstracts" EXACT [MeSH:D016416] xref: MeSH:D016416 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000191 name: advertisement namespace: pub_type comment: This term was obsoleted because it only ever used to annotate a couple of publications. subset: camcur is_obsolete: true [Term] id: FBcv:0000192 name: autobiography namespace: pub_type def: "A work consisting of a self-described account." [http://www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?view=expanded&field=uid&term=D020493] subset: camcur xref: MeSH:D020493 is_a: FBcv:0000194 ! biography [Term] id: FBcv:0000193 name: bibliographic list namespace: pub_type def: "A work consisting of a list of books, articles, documents, publications, and other items, usually on a single subject or related subjects." [http://www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?view=expanded&field=uid&term=D016417] subset: camcur synonym: "Bibliography" EXACT [MeSH:D016417] xref: MeSH:D016417 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000194 name: biography namespace: pub_type def: "A work consisting of an account of the events, works, and achievements, personal and professional, during a person's life. This class includes articles on the activities and accomplishments of living persons as well as the presentation of an obituary." [http://www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?view=expanded&field=uid&term=D019215] subset: camcur xref: MeSH:D019215 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000195 name: book namespace: pub_type def: "A publication on a single subject or related subjects that is complete in itself, whether constructed of chapters, sections, or parts, and that is not issued on a regular, ongoing basis. Every chapter is written by the same author or authors of the publication." [FBC:SM] comment: For books (in the common sense of the term) that have different authors for each chapter, please use 'edited book'. subset: camcur is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000196 name: booklet namespace: pub_type comment: This term was obsoleted because it was little used in curation. The formerly associated publications have mainly been annotated with other, more appropriate publication classes. subset: camcur is_obsolete: true [Term] id: FBcv:0000197 name: book review namespace: pub_type def: "A work consisting of a critical analysis of one or more books or other monographic works." [http://www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?view=expanded&field=uid&term=D022921] subset: camcur synonym: "Book Reviews" EXACT [MeSH:D022921] xref: MeSH:D022921 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000198 name: computer file namespace: pub_type subset: camcur synonym: "CD-ROM" RELATED [] is_obsolete: true [Term] id: FBcv:0000199 name: conference report namespace: pub_type def: "The published records of the papers delivered at or issued on the occasion of individual congresses, symposia, and meetings; abstracts of papers delivered at such congresses; reports of the officers and delegates of such congresses; combinations of the foregoing; or proceedings of the conference of a society if they are not limited to matters of internal organization." [http://www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?view=expanded&field=uid&term=D016423] comment: The definition is taken straight from the MeSH term Congresses, which PubMed uses to annotate both meeting reports written by attendees and conference abstract books. This term should therefore be used to index both of these two rather different artefacts. subset: camcur synonym: "conference proceedings" NARROW [] synonym: "Congresses" EXACT [MeSH:D016423] synonym: "meeting report" NARROW [] xref: MeSH:D016423 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000200 name: demonstration namespace: pub_type comment: This term was obsoleted because it was little used. All publications associated with it have been re-annotated with other publication classes. subset: camcur is_obsolete: true [Term] id: FBcv:0000201 name: DNA/RNA sequence record namespace: pub_type def: "A record of a DNA or RNA sequence in some standard format, such as GenBank or EMBL or DDBJ." [FBC:DOS, FBC:SM] subset: camcur is_a: FBcv:0000789 ! sequence record [Term] id: FBcv:0000202 name: protein sequence record namespace: pub_type def: "A record of a protein sequence in some standard format, such as UniProtKB." [FBC:SM] subset: camcur is_a: FBcv:0000789 ! sequence record [Term] id: FBcv:0000203 name: erratum namespace: pub_type def: "A work consisting of an acknowledgment of an error, issued by a publisher, editor, or author." [http://www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?view=expanded&field=uid&term=D016425] subset: camcur synonym: "correction" EXACT [] synonym: "Corrigendum" EXACT [MeSH:D016425] synonym: "Published Erratum" EXACT [MeSH:D016425] xref: MeSH:D016425 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000204 name: film namespace: pub_type def: "A film or video that is factual, documentary or instructional in character." [FBC:SM, MeSH:D019499, MeSH:D019514] subset: camcur synonym: "video" NARROW [] is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000205 name: interview namespace: pub_type def: "A work consisting of a conversation with an individual regarding his or her background and other personal and professional details, opinions on specific subjects posed by the interviewer." [http://www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?view=expanded&field=uid&term=D017203] subset: camcur xref: MeSH:D017203 is_a: FBcv:0000194 ! biography [Term] id: FBcv:0000206 name: jigsaw puzzle namespace: pub_type comment: This term was obsoleted because it only ever used to annotate one, unarchived publication. subset: camcur is_obsolete: true [Term] id: FBcv:0000207 name: letter namespace: pub_type def: "A work consisting of written or printed communication between individuals or between persons and representatives of corporate bodies. The correspondence may be personal or professional." [http://www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?view=expanded&field=uid&term=D016422] comment: In medical and other scientific publications the letter is usually from one or more authors to the editor of the journal or book publishing the item being commented upon or discussed. subset: camcur xref: MeSH:D016422 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000208 name: microscope slides namespace: pub_type comment: This term was obsoleted because it had only been used once in FlyBase, and this was for an artefact that is not present in a FlyBase associated archive. The associated record in FlyBase CHADO has been obsoleted. subset: camcur is_obsolete: true [Term] id: FBcv:0000209 name: news article namespace: pub_type def: "A work consisting of an announcement or statement of recent or current events of new data and matters of interest in the field of medicine or science, published in a scientific journal." [FBC:SM, MeSH:D016433] subset: camcur xref: MeSH:D016433 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000210 name: note namespace: pub_type def: "A work consisting of a critical or explanatory note written to discuss, support, or dispute an article or other presentation previously published." [http://www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?view=expanded&field=uid&term=D016420] subset: camcur synonym: "Comment" EXACT [MeSH:D016420] xref: MeSH:D016420 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000211 name: obituary namespace: pub_type def: "A published announcement of a death accompanied by a short biography of the deceased." [FBC:SM] subset: camcur is_a: FBcv:0000194 ! biography [Term] id: FBcv:0000212 name: paper namespace: pub_type def: "An article reporting original research, published in a peer-reviewed journal." [FBC:SM] comment: Note that this is a much more specific class than that referred to by MeSH Journal article (D016428). subset: camcur synonym: "Journal article" BROAD [MeSH:D016428] xref: MeSH:D016428 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000213 name: patent namespace: pub_type def: "A work consisting of documents granted by a government giving exclusive rights to an inventor or assignee to manufacture, use, or sell an invention for a certain number of years." [http://www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?view=expanded&field=uid&term=D020490] subset: camcur xref: MeSH:D020490 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000214 name: personal communication to FlyBase namespace: pub_type def: "A work that has not been formally published and that consists of observations or data submitted by a researcher or group of researchers directly to FlyBase." [FBC:DOS, FBC:SM] subset: camcur is_a: FBcv:0000233 ! unpublished [Term] id: FBcv:0000215 name: poem namespace: pub_type def: "A literary or oral work expressing meaning via symbolism and following formal or informal patterns." [http://www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?view=expanded&field=uid&term=D055821] subset: camcur synonym: "poetry" EXACT [MeSH:D055821] xref: MeSH:D055821 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000216 name: poster namespace: pub_type def: "A work consisting of a single or multi-sheet notice made to attract attention to events, activities, causes, goods, or services. It is for posting, usually in a public place and is chiefly pictorial. It is intended to make an immediate impression from a distance." [http://www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?view=expanded&field=uid&term=D019519] comment: The class does not encompass poster presentations at conferences and meetings. subset: camcur xref: MeSH:D019519 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000217 name: press release namespace: pub_type def: "A written or recorded communication directed at members of the news media for the purpose of announcing something ostensibly newsworthy." [http://en.wikipedia.org/w/index.php?title=Press_release&oldid=482495713] subset: camcur is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000218 name: recording namespace: pub_type comment: This term has been obsoleted because it was little used in curation and the artefacts annotated with it are not present in any FlyBase associated archive. Records annotated with this term have been obsoleted in the FlyBase CHADO database. subset: camcur is_obsolete: true [Term] id: FBcv:0000219 name: retraction namespace: pub_type def: "A work consisting of a statement issued by one or more authors of an article or a book, withdrawing or disavowing acknowledgment of their participation in performing research or writing the results of their study." [http://www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?view=expanded&field=uid&term=D016440] subset: camcur synonym: "Retraction of Publication" EXACT [MeSH:D016440] xref: MeSH:D016440 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000220 name: review namespace: pub_type def: "An article or book published after examination of published material on a subject." [http://www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?view=expanded&field=uid&term=D016454] comment: The reviews most often desired are reviews of the current literature, but a review of historical literature is also within the scope of this publication type. subset: camcur xref: MeSH:D016454 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000221 name: slides namespace: pub_type comment: This term has been obsoleted because it was little used in curation and the artefacts annotated with it are not present in any FlyBase associated archive. subset: camcur is_obsolete: true [Term] id: FBcv:0000222 name: spoof namespace: pub_type def: "A mildly satirical mockery or parody of a conventional publication type." [FBC:SM] subset: camcur xref: MeSH:D020480 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000223 name: stock list namespace: pub_type def: "A list of Drosophila stocks kept by a specified stock center or research group." [FBC:SM] subset: camcur is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000224 name: supplementary material namespace: pub_type def: "Supporting content or information, such as animation, datasets, multimedia files, video, movies, audio files, text files, or software, which is submitted for publication in an online journal or an online edition of a journal. This information may be referenced in the text of the article with a link to the supplementary data provided." [http://www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?view=expanded&field=uid&term=D058537] subset: camcur synonym: "additional files" EXACT [] synonym: "Electronic Supplementary Materials" EXACT [MeSH:D058537] synonym: "supplementary information" EXACT [] synonym: "supporting information" EXACT [] xref: MeSH:D058537 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000225 name: T-shirt namespace: pub_type comment: This term was obsoleted because it had been used only once in ~20 years of curation. subset: camcur is_obsolete: true [Term] id: FBcv:0000226 name: tactile diagram namespace: pub_type def: "A diagram that is designed to be touched, rather than looked at. These are generally made for use by blind or visually impaired people." [FBC:DOS] subset: camcur is_obsolete: true [Term] id: FBcv:0000227 name: teaching note namespace: pub_type def: "An article describing exercises or practicals suitable for teaching." [FBC:SM] subset: camcur is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000228 name: thesis namespace: pub_type def: "A work consisting of a formal presentation made usually to fulfill requirements for an academic degree." [http://www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?view=expanded&field=uid&term=D019478] subset: camcur synonym: "Academic Dissertations" EXACT [MeSH:D019478] xref: MeSH:D019478 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000229 name: curated genome annotation namespace: pub_type def: "A systematic effort to annotate gene models on a sequenced Drosophila genome, such as those conducted for D. melanogaster at the Celera Jamboree. Annotations may be performed manually or automatically." [FBC:SM] comment: Note that the name of this publication type will change to simply 'genome annotation', but this change has been delayed pending required work on the database. subset: camcur synonym: "automatic genome annotation" RELATED [] is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000230 name: automatic genome annotation namespace: pub_type comment: This term was obsoleted becuase it was hardly ever used. Please use FBcv:0000229 instead. subset: camcur is_obsolete: true replaced_by: FBcv:0000229 [Term] id: FBcv:0000231 name: white paper namespace: pub_type def: "A work consisting of a set of statements, directions, or principles presenting current or future rules or policy." [FBC:SM, http://www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?view=expanded&field=uid&term=D016431] subset: camcur synonym: "Guideline" BROAD [MeSH:D016431] xref: MeSH:D016431 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000232 name: recessive lethal balancer for chromosome 3 is_obsolete: true [Term] id: FBcv:0000233 name: unpublished namespace: pub_type def: "A work that has not been formally published." [http://www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?view=expanded&field=uid&term=D022902] subset: camcur synonym: "privately distributed report" RELATED [] synonym: "Unpublished Works" EXACT [MeSH:D022902] xref: MeSH:D022902 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000234 name: publication language namespace: language subset: camcur is_a: FBcv:0000188 ! publication descriptor [Term] id: FBcv:0000235 name: Afrikaans namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000236 name: Arabic namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000237 name: Armenian namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000238 name: Belarussian namespace: language subset: camcur synonym: "Belarusian" RELATED [] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000239 name: Bulgarian namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000240 name: Catalan namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000241 name: Chinese namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000242 name: Cumbrian namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000243 name: Czech namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000244 name: Danish namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000245 name: Dutch namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000246 name: English namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000247 name: Estonian namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000248 name: Faroese namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000249 name: Farsi namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000250 name: Finnish namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000251 name: Flemish namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000252 name: French namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000253 name: German namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000254 name: Greek namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000255 name: Hebrew namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000256 name: Hungarian namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000257 name: Icelandic namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000258 name: Indonesian namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000259 name: Italian namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000260 name: Japanese namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000261 name: Jugoslavian namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000262 name: Korean namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000263 name: Latin namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000264 name: Latvian namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000265 name: Lithuanian namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000266 name: Malay namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000267 name: Malayalam namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000268 name: Norwegian namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000269 name: Polish namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000270 name: Portuguese namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000271 name: Serbo-Croat(Roman) namespace: language subset: camcur is_a: FBcv:0000274 ! Serbo-Croat [Term] id: FBcv:0000272 name: Romanian namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000273 name: Russian namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000274 name: Serbo-Croat namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000275 name: Slovak namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000276 name: Slovenian namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000277 name: Spanish namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000278 name: Swedish namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000279 name: Turkish namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000280 name: Ukrainian namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000281 name: Yiddish namespace: language subset: camcur is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000282 name: mutant scorability rank namespace: scorability is_a: FBcv:0000807 ! allele descriptor [Term] id: FBcv:0000283 name: RK1 namespace: scorability def: "The RK1 rank describes mutants that are easily scored." [FlyBase:FBrf0066905] subset: camcur is_a: FBcv:0000282 ! mutant scorability rank [Term] id: FBcv:0000284 name: RK2 namespace: scorability def: "The RK2 rank describes mutants that usable but less convenient." [FlyBase:FBrf0066905] subset: camcur is_a: FBcv:0000282 ! mutant scorability rank [Term] id: FBcv:0000285 name: RK3 namespace: scorability def: "The RK3 rank describes mutants that are of limited usefulness." [FlyBase:FBrf0066905] subset: camcur is_a: FBcv:0000282 ! mutant scorability rank [Term] id: FBcv:0000286 name: allele class namespace: allele_class synonym: "allele morphy class" EXACT [] is_a: FBcv:0000807 ! allele descriptor [Term] id: FBcv:0000287 name: loss of function allele namespace: allele_class def: "An allele that either makes no functional gene product, makes reduced levels of a normally functioning gene product or makes a gene product with reduced activity compared to wild-type" [FlyBase:FBrf0049147] comment: Loss of function alleles are generally, but not exclusively, recessive. At haplo-insufficient loci (loci that require two copies for normal function), loss of function alleles can be dominant. subset: camcur is_a: FBcv:0000286 ! allele class [Term] id: FBcv:0000288 name: amorphic allele - genetic evidence namespace: allele_class def: "An allele inferred to completely lack function from the observation that addition of extra copies in the genome has no effect on the phenotype. Most commonly, evidence takes the form of the observation that the phenotype of homozygotes (2 copies) is identical to that seen when the allele is in trans to a deletion of the gene (1 copy)." [FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000688 ! amorphic allele [Term] id: FBcv:0000289 name: hypomorphic allele - genetic evidence namespace: allele_class def: "Allele inferred to make a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity from the observation that extra copies in the genome decrease the expressivity and/or penetrance of the phenotype. Most commonly this evidence takes the form of experiments showing that the homozygote (2 copies) has a weaker phenotype than the allele in trans to a deletion of the gene (1 copy))." [FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000690 ! hypomorphic allele [Term] id: FBcv:0000290 name: gain of function allele namespace: allele_class def: "An allele that either makes a normally functioning gene product but at higher levels or in a different spatial or temporal pattern to wild-type, or a product with increased or novel activity compared to wild-type." [FlyBase:FBrf0049147] comment: Gain of function alleles are generally dominant. But not all dominant alleles are gain of function alleles. subset: camcur is_a: FBcv:0000286 ! allele class [Term] id: FBcv:0000291 name: neomorphic allele - genetic evidence namespace: allele_class def: "An allele that is inferred to make a gene product with a novel function or expression pattern compared to wild-type based on the evidence that the phenotype is unaffected by extra or fewer doses of the wild-type gene." [FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000697 ! neomorphic allele [Term] id: FBcv:0000292 name: antimorphic allele - genetic evidence namespace: allele_class def: "An allele that is inferred to make a gene product that is antagonistic to the wild-type gene product from the observations that extra copies of the wild-type allele reduce the expressivity and/or penetrance of the phenotype. So, the phenotype over a deficiency is stronger than that over a wild-type allele, which in turn is stronger than that in the presence of a duplication of the wild-type locus. This test is similar to that used for hypomorphic alleles. An antimorph can be distinguished from a dominant hypermorph as only the former can be reverted to wild-type by deletion of the mutant allele. " [FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000695 ! antimorphic allele [Term] id: FBcv:0000293 name: hypermorphic allele - genetic evidence namespace: allele_class def: "An allele inferred to make either increased amounts of a normal gene product or a gene product with normal function but increased activity compared to wild-type from the observation that extra copies in the genome increase the expressivity and/or penetrance of the phenotype. Most commonly this evidence takes the form of experiments showing that homozygotes (2 copies) have a stronger phenotype than transheterozygotes to a deletion of the gene (1 copy)." [FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000696 ! hypermorphic allele [Term] id: FBcv:0000294 name: wild-type allele namespace: allele_class subset: camcur is_a: FBcv:0000286 ! allele class [Term] id: FBcv:0000295 name: wild-type generic namespace: allele_class subset: camcur is_a: FBcv:0000294 ! wild-type allele [Term] id: FBcv:0000296 name: isoallele namespace: allele_class subset: camcur is_a: FBcv:0000294 ! wild-type allele [Term] id: FBcv:0000297 name: extracted wild-type chromosome 1 is_obsolete: true [Term] id: FBcv:0000298 name: recessive namespace: dominance_qualifier def: "A phenotypic attribute is described as recessive when it is manifest only in individuals homozygous or hemizygous for the allele that causes that phenotype." [ISBN:978-0-8053-0316-2] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. subset: camcur is_a: FBcv:0000565 ! dominance relationship qualifier [Term] id: FBcv:0000299 name: dominant namespace: dominance_qualifier def: "A phenotypic attribute is described as dominant when it is manifest in individuals heterozygous for the allele that causes that phenotype." [ISBN:978-0-8053-0316-2] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. subset: camcur is_a: FBcv:0000565 ! dominance relationship qualifier [Term] id: FBcv:0000300 name: codominant namespace: dominance_qualifier def: "A phenotypic attribute is described as codominant when it is manifest in individuals carrying the allele that causes that phenotype, irrespective of the homologous allele." [ISBN:978-0-8053-0316-2] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. subset: camcur is_a: FBcv:0000299 ! dominant [Term] id: FBcv:0000301 name: semidominant namespace: dominance_qualifier def: "A phenotypic attribute is described as semidominant when individuals heterozygous for the allele show phenotypes part way between homozygotes for either allele." [ISBN:978-0-8053-0316-2] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. subset: camcur is_a: FBcv:0000299 ! dominant [Term] id: FBcv:0000302 name: extracted wild-type chromosome 2 is_obsolete: true [Term] id: FBcv:0000303 name: extracted wild-type chromosome 3 is_obsolete: true [Term] id: FBcv:0000304 name: extracted wild-type chromosome 4 is_obsolete: true [Term] id: FBcv:0000305 name: extracted wild-type chromosome Y is_obsolete: true [Term] id: FBcv:0000306 name: sex limited namespace: sex_qualifier def: "Expression is limited to one or other sex by virtue of the particular biology of that sex, rather than the sex-linkage of the genes underlying the attribute." [FlyBase:FBrf0075559] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. May be used to qualify expression of phenotypes or of genes, transgenes etc. subset: camcur is_a: FBcv:0000332 ! sex [Term] id: FBcv:0000307 name: male limited namespace: sex_qualifier def: "Expression is limited to males by virtue of the particular biology of males, rather than the sex-linkage of the gene(s) involved." [FlyBase:FBrf0075559] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. May be used to qualify expression of phenotypes or of genes, transgenes etc. subset: camcur is_a: FBcv:0000306 ! sex limited [Term] id: FBcv:0000308 name: female limited namespace: sex_qualifier def: "Expression is limited to females by virtue of the particular biology of females, rather than the sex-linkage of the gene(s) involved." [FlyBase:FBrf0075559] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. May be used to qualify expression of phenotypes or of genes, transgenes etc. subset: camcur is_a: FBcv:0000306 ! sex limited [Term] id: FBcv:0000309 name: conditional namespace: environmental_qualifier def: "Phenotype expressed only under specific environmental conditions that do not induce the same defect in wild-type animals." [FBC:DOS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur synonym: "conditional qualifier" RELATED [] is_a: FBcv:0000005 ! qualifier [Term] id: FBcv:0000310 name: temperature conditional namespace: environmental_qualifier def: "Phenotype only expressed in some subset of the temperature range within which wild-type animals are viable." [FBC:DOS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000309 ! conditional [Term] id: FBcv:0000311 name: heat sensitive namespace: environmental_qualifier def: "Phenotype only expressed at high temperatures." [FBC:DOS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur synonym: "conditional - heat sensitive" EXACT [] synonym: "conditional ts" EXACT [] synonym: "hs" EXACT [] is_a: FBcv:0000310 ! temperature conditional [Term] id: FBcv:0000312 name: cold sensitive namespace: environmental_qualifier def: "Phenotype only expressed at low temperatures." [FBC:DOS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur synonym: "conditional - cold sensitive" EXACT [] synonym: "conditional cs" EXACT [] synonym: "cs" EXACT [] is_a: FBcv:0000310 ! temperature conditional [Term] id: FBcv:0000313 name: drug conditional namespace: environmental_qualifier def: "Phenotype expressed only in the presence of some specific drug (CHEBI:23888) whose presence does not induce the same defect in wild-type animals." [FBC:DOS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000704 ! chemical conditional [Term] id: FBcv:0000314 name: RU486 conditional namespace: environmental_qualifier def: "Phenotype expressed only in the presence of RU486 (CHEBI:50692), also known as mifepristone." [FBC:DOS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur synonym: "conditional mifepristone" EXACT [] synonym: "conditional RU486" EXACT [] is_a: FBcv:0000313 ! drug conditional [Term] id: FBcv:0000315 name: tetracycline conditional namespace: environmental_qualifier def: "Phenotype expressed only in the presence of tetracycline (CHEBI:27902)." [FBC:DOS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q.q subset: camcur synonym: "conditional tetracycline" EXACT [] is_a: FBcv:0000313 ! drug conditional [Term] id: FBcv:0000316 name: homeotic namespace: phenotypic_class def: "Phenotype that is the partial or full transformation of one or more segments (FBbt:00000003) or segmental appendages from one identity to another. For example, in antennapedia an antenna is partially or fully transformed into a leg." [FBC:DOS] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000317 name: isogenic chromosome 1 is_obsolete: true [Term] id: FBcv:0000318 name: isogenic chromosome 2 is_obsolete: true [Term] id: FBcv:0000319 name: gap expression pattern namespace: embryonic_pattern_qualifier def: "Expression across a contiguous block of two or more segments of the blastoderm." [FBC:DOS] is_a: FBcv:0000654 ! embryonic pattern qualifier [Term] id: FBcv:0000320 name: terminal expression pattern namespace: embryonic_pattern_qualifier def: "Expression in the terminal regions of the embryo/larva: the acron, telson and adjacent segments." [FBC:DOS] synonym: "terminal" RELATED [] is_a: FBcv:0000654 ! embryonic pattern qualifier [Term] id: FBcv:0000321 name: isogenic chromosome 3 is_obsolete: true [Term] id: FBcv:0000322 name: pair rule expression pattern namespace: embryonic_pattern_qualifier def: "Expression in alternate segments of the blastoderm." [FBC:DOS] is_a: FBcv:0000654 ! embryonic pattern qualifier [Term] id: FBcv:0000323 name: segment polarity expression pattern namespace: embryonic_pattern_qualifier is_a: FBcv:0000654 ! embryonic pattern qualifier [Term] id: FBcv:0000324 name: dorsal/ventral axis specification defective namespace: phenotypic_class def: "Phenotype that is a defect in dorsal/ventral axis specification (GO:0009950). 'dorsal/ventral axis specification' is defined as: 'The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.'" [FBC:DOS, GOC:dph, GOC:go_curators, GOC:tb] subset: camcur synonym: "dorsal-ventral polarity" RELATED [FBC:DOS] is_a: FBcv:0000686 ! axis specification defective [Term] id: FBcv:0000325 name: neurogenic phenotype namespace: phenotypic_class def: "A phenotype that is an expansion of the developing embryonic nervous system at the expense of developing ventral epidermis." [FlyBase:FBrf0040185] comment: Typically this is caused by and expansion of the population of neuroblasts at the expense of prospective epidermis, both of which originate in the ventral ectoderm. subset: camcur is_a: FBcv:0001347 ! phenotype created_by: djs93 creation_date: 2011-09-13T02:42:10Z [Term] id: FBcv:0000326 name: isogenic chromosome 4 is_obsolete: true [Term] id: FBcv:0000327 name: P-element transposase source for transposable element mutagenesis is_obsolete: true [Term] id: FBcv:0000328 name: hobo transposase source for transposable element mutagenesis is_obsolete: true [Term] id: FBcv:0000329 name: piggyBac transposase source for transposable element mutagenesis is_obsolete: true [Term] id: FBcv:0000330 name: minos transposase source for transposable element mutagenesis is_obsolete: true [Term] id: FBcv:0000331 name: polyphasic namespace: temporal_qualifier comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q.\n\nDeprecated: Use of this term is discouraged as there is no way to decide how to group anatomy terms combined with this qualifier with other terms in the anatomy ontology. Subject to discussion and once its usage in old curation is removed, this term will be obsoleted. DS xref: PATO:0001774 is_a: FBcv:0000009 ! temporal stage qualifier [Term] id: FBcv:0000332 name: sex namespace: sex_qualifier synonym: "sex qualifier" EXACT [FBC:DOS] is_a: FBcv:0000005 ! qualifier [Term] id: FBcv:0000333 name: male namespace: sex_qualifier def: "Expressed in males." [FBC:DOS] comment: This term has historically been used as a qualifier for expression and phenotype, but its use for phenotype has been deprecated. Its use does not imply expression exclusively in males. is_a: FBcv:0000332 ! sex [Term] id: FBcv:0000334 name: female namespace: sex_qualifier def: "Expressed in females." [FBC:DOS] comment: This term has historically been used as a qualifier for expression and phenotype, but its use for phenotype has been deprecated. Its use does not imply expression exclusively in females. is_a: FBcv:0000332 ! sex [Term] id: FBcv:0000335 name: germline clone namespace: clone_qualifier def: "A clone of germline cells that share a genotype." [FBC:DOS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur synonym: "germ-line clone" EXACT [] is_a: FBcv:0000812 ! clone of cells [Term] id: FBcv:0000336 name: somatic clone namespace: clone_qualifier def: "A clone of somatic cells that share a genotype that is different from the genotype of the animal in which it resides and from which it is derived." [FBC:DOS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000812 ! clone of cells [Term] id: FBcv:0000337 name: P-element ammunition for transposable element mutagenesis is_obsolete: true [Term] id: FBcv:0000338 name: hobo ammunition for transposable element mutagenesis is_obsolete: true [Term] id: FBcv:0000339 name: fully namespace: extent comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. \n\nDeprecated: Use of this term is discouraged as 'fully' assumed in the absence of use of 'partially'. is_a: FBcv:0000811 ! qualitative qualifier [Term] id: FBcv:0000340 name: partially namespace: extent def: "Incomplete penetrance or expressivity of a phenotype or incomplete suppression of a phenotype." [FBC:DOS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Note on usage: This qualifier should not be used in combination with lethal, viable, sterile or fertile. For these cases, terms of the form semi-X should be used instead. subset: camcur is_a: FBcv:0000811 ! qualitative qualifier [Term] id: FBcv:0000341 name: good namespace: intensity_qualifier is_a: FBcv:0000811 ! qualitative qualifier [Term] id: FBcv:0000342 name: poor namespace: intensity_qualifier is_a: FBcv:0000811 ! qualitative qualifier [Term] id: FBcv:0000343 name: reduced namespace: intensity_qualifier is_a: FBcv:0000811 ! qualitative qualifier [Term] id: FBcv:0000344 name: slow namespace: intensity_qualifier xref: PATO:0000304 is_a: FBcv:0000811 ! qualitative qualifier [Term] id: FBcv:0000345 name: fast namespace: intensity_qualifier xref: PATO:0000303 is_a: FBcv:0000811 ! qualitative qualifier [Term] id: FBcv:0000346 name: intermediate namespace: intensity_qualifier is_a: FBcv:0000811 ! qualitative qualifier [Term] id: FBcv:0000347 name: phenotypic class namespace: phenotypic_class is_a: FBcv:0000807 ! allele descriptor [Term] id: FBcv:0000348 name: wild-type namespace: phenotypic_class def: "The cannonical phenotype of a wild-type Drosophilid." [FBC:DOS] subset: camcur is_a: FBcv:0000347 ! phenotypic class disjoint_from: FBcv:0001347 ! phenotype [Term] id: FBcv:0000349 name: viable namespace: phenotypic_class def: "A phenotype that is survival to mature adulthood, where mature is defined as after adult stage A3 (FBdv:00006012)." [FBC:DOS] comment: Proforma field: MA8. Note, this term should not be used with the qualifier 'partially'. Use semi-viable or semi-lethal instead. subset: camcur is_a: FBcv:0000347 ! phenotypic class [Term] id: FBcv:0000350 name: partially lethal - majority live namespace: phenotypic_class def: "A phenotype of a population that is the death of some significant proportion of animals in that population, but less that half, prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012)." [FBC:DOS] subset: camcur synonym: "semi-viable" EXACT [] is_a: FBcv:0000349 ! viable is_a: FBcv:0002015 ! partially lethal [Term] id: FBcv:0000351 name: lethal namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population at some stage or stages prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012)." [FBC:DOS, FBC:KM] comment: Note on usage: lethal is appropriate in cases where escaper adults are very rare. The lethal phase prior to becoming a mature adult may be further specified multiple stage qualifiers. subset: camcur is_a: FBcv:0002019 ! increased mortality during development [Term] id: FBcv:0000352 name: partially lethal - majority die namespace: phenotypic_class def: "A phenotype of a population that is the death a majority of animals in that population prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012)." [FBC:DOS, FBC:KM, FBC:NB] comment: Stages during which there is significant death prior to mature adulthood can be indicated using one or more stage qualifiers. subset: camcur synonym: "semi-lethal" EXACT [] is_a: FBcv:0002015 ! partially lethal [Term] id: FBcv:0000353 name: cell lethal namespace: phenotypic_class def: "A phenotype that is a failure of mutant cells to survive." [FBC:DOS] comment: Typically, this phenotype is assayed in clones of cells. subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000354 name: visible namespace: phenotypic_class def: "A post-embryonic, macroscopic, anatomical phenotype." [FBC:DOS] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000355 name: eye color defective namespace: phenotypic_class def: "Phenotype that is a defect in eye color compared to wild-type." [FBC:DOS] subset: camcur synonym: "eye colour defective" EXACT [] is_a: FBcv:0000354 ! visible [Term] id: FBcv:0000356 name: body color defective namespace: phenotypic_class def: "A phenotype that is a defect in body color compared to wild-type." [FBC:DOS] subset: camcur synonym: "body colour defective" EXACT [] is_a: FBcv:0000354 ! visible [Term] id: FBcv:0000357 name: size defective namespace: phenotypic_class def: "A phenotype that is a defect in the size of the whole body or some body part compared to wild-type." [FBC:DOS] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000358 name: small body namespace: phenotypic_class def: "Phenotype that is a decrease in body size compared to identically raised wild-type controls." [FBC:DOS] subset: camcur is_a: FBcv:0000665 ! body size defective [Term] id: FBcv:0000359 name: decreased cell number namespace: phenotypic_class def: "Phenotype that is a decrease in the number of cells in a whole animal or in some specific organ, tissue or clone of cells compared to wild-type. This phenotype is not necessarily accompanied by decreased growth - there may be fewer cells in an otherwise normal volume of tissue." [FBC:DOS] subset: camcur synonym: "reduced cell number" EXACT [] is_a: FBcv:0000709 ! cell number defective [Term] id: FBcv:0000360 name: decreased cell size namespace: phenotypic_class def: "Phenotype that is a decrease in the size of cells in a whole animal or in some specific organ, tissue or clone of cells compared to wild-type. This phenotype is not necessarily accompanied by decreased growth of a tissue - there may be more cells in an otherwise normal volume of tissue." [FBC:DOS] comment: Note that defects in cell size are not necessarily the result of defects in cell growth. A change in the rate of cell division in the absence of any change in cell growth rate can result in smaller or larger cells. subset: camcur synonym: "reduced cell size" EXACT [] is_a: FBcv:0000428 ! cell size defective [Term] id: FBcv:0000361 name: large body namespace: phenotypic_class def: "Phenotype that is an increase in body size compared to identically raised wild-type controls." [FBC:DOS] subset: camcur is_a: FBcv:0000665 ! body size defective [Term] id: FBcv:0000362 name: increased cell number namespace: phenotypic_class def: "Phenotype that is an increase in the number of cells in a whole animal or in some specific organ, tissue or clone of cells compared to wild-type." [FBC:DOS] comment: This phenotype is not necessarily accompanied by overgrowth of a tissue - there may be more cells in an otherwise normal volume of tissue. It is not necessarily due to an increase in cell growth -it may be the result of an increase in the division rate at normal growth rates. It may not even be due to an increase in the cell division rate - a reduced rate of cell death while the division rate is normal could also achieve it. subset: camcur is_a: FBcv:0000709 ! cell number defective [Term] id: FBcv:0000363 name: increased cell size namespace: phenotypic_class def: "Phenotype that is an increase in the size of cells compared to wild-type." [FBC:DOS] comment: May be due to an increase in the cell growth rate or to a reduced rate of cell division along with a normal rate of cell growth. subset: camcur is_a: FBcv:0000428 ! cell size defective [Term] id: FBcv:0000364 name: sterile namespace: phenotypic_class def: "A phenotype that is the inability to produce a zygote." [FBC:DOS] comment: The cause of sterility may be physical or behavioral. Note, this term should not be used with the qualifier 'partially'. Use semi-sterile or semi-fertile instead. subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000365 name: semi-sterile namespace: phenotypic_class def: "A phenotype that is a reduction in the proportion of fertilized eggs produced to below 50% of wild-type." [FBC:DOS] subset: camcur synonym: "reduced fecundity" BROAD [FBC:DOS] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000366 name: female sterile namespace: phenotypic_class def: "A phenotype that is the inability of females to mate and produce fertilized offspring." [FBC:DOS] comment: The cause of sterility may be physical or behavioral. Note: this term should not be used with the qualifier 'partially' - use semi-sterile or semi-fertile instead. subset: camcur is_a: FBcv:0000364 ! sterile [Term] id: FBcv:0000367 name: female semi-sterile namespace: phenotypic_class def: "A phenotype that is a reduction in the proportion of fertilized eggs produced by females to below 50% of wild-type." [FBC:DOS] subset: camcur is_a: FBcv:0000365 ! semi-sterile [Term] id: FBcv:0000368 name: female sterile germline-dependent namespace: phenotypic_class def: "A phenotype of female sterility due to defects in the female germline." [FBC:DOS] subset: camcur synonym: "female sterile germ-line-dependent" EXACT [] is_a: FBcv:0000366 ! female sterile [Term] id: FBcv:0000369 name: female sterile soma-dependent namespace: phenotypic_class def: "A phenotype of female sterility due to defects in somatic cells of the ovary (FBbt:00006030), or of the products of these cells (such as eggshell)." [FBC:DOS] subset: camcur is_a: FBcv:0000366 ! female sterile [Term] id: FBcv:0000370 name: male sterile namespace: phenotypic_class def: "A phenotype that is the inability of males to mate and produce fertilized offspring." [FBC:DOS] comment: The cause of sterility may be physical or behavioral. Note - this term should not be used with the qualifier 'partially' - use semi-sterile or semi-fertile instead. subset: camcur is_a: FBcv:0000364 ! sterile [Term] id: FBcv:0000371 name: male semi-sterile namespace: phenotypic_class def: "A phenotype that is a reduction in the proportion of fertilized eggs produced by males to below 50% of wild-type." [FBC:DOS] subset: camcur is_a: FBcv:0000365 ! semi-sterile [Term] id: FBcv:0000372 name: male sterile germline-dependent namespace: phenotypic_class def: "A phenotype of male sterility due to defects in the male germline." [FBC:DOS] subset: camcur synonym: "male sterile germ-line-dependent" EXACT [] is_a: FBcv:0000370 ! male sterile [Term] id: FBcv:0000373 name: male sterile soma-dependent namespace: phenotypic_class def: "A phenotype of male sterility due to defects in somatic cells of the testis (FBbt:00006031) or of the products of these cells." [FBC:DOS] subset: camcur is_a: FBcv:0000370 ! male sterile [Term] id: FBcv:0000374 name: fertile namespace: phenotypic_class def: "A phenotype that is the ability to mate and as a result produce fertilized eggs." [FBC:DOS] comment: Note, this term should not be used with the qualifier 'partially'. Use semi-sterile or semi-fertile instead. subset: camcur is_a: FBcv:0000347 ! phenotypic class [Term] id: FBcv:0000375 name: semi-fertile namespace: phenotypic_class def: "Phenotype that is a reduction in the proportion of fertilized eggs produced to, but only to > 50% of wild-type." [FBC:DOS] subset: camcur synonym: "reduced fecundity" BROAD [FBC:DOS] is_a: FBcv:0000374 ! fertile is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000376 name: male fertile namespace: phenotypic_class def: "A phenotype that is the ability of males to mate and as a result produce fertilized eggs." [FBC:DOS] comment: Note - this term should not be used with the qualifier 'partially' - use male semi-sterile or male semi-fertile instead. subset: camcur is_a: FBcv:0000374 ! fertile [Term] id: FBcv:0000377 name: female fertile namespace: phenotypic_class def: "A phenotype that is the ability of females to mate and as a result produce fertilized eggs." [FBC:DOS] comment: Note - this term should not be used with the qualifier 'partially' - use female semi-sterile or female semi-fertile instead. subset: camcur is_a: FBcv:0000374 ! fertile [Term] id: FBcv:0000378 name: grandchildless namespace: phenotypic_class def: "A phenotype in which all offspring are sterile. Typically, this is due to maternal effect sterility resulting from defects in pole cell development." [ISBN:978-0-87969-321-3] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000379 name: enhancer of variegation namespace: phenotypic_class def: "Genotype g1 is an enhancer of variegation if, and only if, some genotype g2 has a variegated phenotype and the degree of variegation caused by g1g2 is greater than that caused by g2 alone." [FBC:DOS] comment: Typically, g2 is a chromosomal aberration or an insertion. subset: camcur is_a: FBcv:0000008 ! modifier of variegation [Term] id: FBcv:0000380 name: non-enhancer of variegation namespace: phenotypic_class def: "Genotype g1 is a non-enhancer of variegation of the phenotype due to genotype g2 if, and only if, g2 has a variegated phenotype and the degree of variegation caused by g1g2 is not greater than that caused by g2 alone." [FBC:DOS] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000381 name: suppressor of variegation namespace: phenotypic_class def: "Genotype g1 is a suppressor of variegation if, and only if, some genotype g2 has a variegated phenotype and the degree of variegation caused by g1g2 is less than that caused by to g2 alone." [FBC:DOS] comment: Typically, g2 is a chromosomal aberration or an insertion. subset: camcur is_a: FBcv:0000008 ! modifier of variegation [Term] id: FBcv:0000382 name: non-suppressor of variegation namespace: phenotypic_class def: "Genotype g1 is a non-suppressor of variegation of the phenotype due to genotype g2 if, and only if, g2 has a variegated phenotype and the degree of variegation caused by g1g2 is not less than that caused by g2 alone." [FBC:DOS] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000383 name: auxotroph namespace: phenotypic_class def: "A phenotype that is the inability to synthesize some organic compound that can be synthesized by wild-type animals, and that is required for normal growth and/or development." [http://en.wikipedia.org/wiki/Auxotrophic] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000384 name: aging defective namespace: phenotypic_class def: "Phenotype that is a defect in aging (GO:0007568). 'aging' is defined as: 'A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death (GO:0016265) and may succeed developmental maturation (GO:0021700).'" [GOC:PO_curators] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000385 name: short lived namespace: phenotypic_class def: "Phenotype that is a shorter adult life-span than wild-type." [FBC:DOS] subset: camcur synonym: "increased adult mortality" EXACT [] is_a: FBcv:0002004 ! increased mortality [Term] id: FBcv:0000386 name: long lived namespace: phenotypic_class def: "Phenotype that is a longer adult life-span than wild-type." [FBC:DOS] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000387 name: behavior defective namespace: phenotypic_class subset: camcur synonym: "behavioral" RELATED [] synonym: "behaviour defective" EXACT [] synonym: "behavioural" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000388 name: gravitaxis defective namespace: phenotypic_class def: "Phenotype that is a change in the strong tendency, seen in wild-type Drosophila melanogaster, to climb - a behavior otherwise known as negative gravitaxis (GO:0048060 ; movement away from the source of gravity)." [FBC:DOS] subset: camcur synonym: "geotaxis behaviour defective" RELATED [] synonym: "gravitaxis behavior defective" RELATED [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000389 name: paralytic namespace: phenotypic_class def: "Phenotype that is a disposition to paralysis under conditions that do not cause paralysis in a wild-type animal. Paralysis is defined as an inability to exhibit `multicellular organismal movement` (GO:0050879)" [FBC:DOS] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000390 name: hypoactive namespace: phenotypic_class def: "A phenotype consisting of decreased frequency of `multicellular organismal movement` (GO:0050879) compared to wild-type." [FBC:DOS] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000391 name: bang sensitive namespace: phenotypic_class def: "A phenotype exhibited following mechanical shock and consisting of a brief period of intense, uncoordinated motor activity (legs and wings flailing, abdomen coiling) followed by a prolonged period of paralysis." [FlyBase:FBrf0022877] subset: camcur synonym: "easily shocked" RELATED [FlyBase:FBrf0022877] is_a: FBcv:0000389 ! paralytic [Term] id: FBcv:0000392 name: hyperactive namespace: phenotypic_class def: "A phenotype consisting of increased frequency of `multicellular organismal movement` (GO:0050879) compared to wild-type." [FBC:DOS] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000393 name: pain response defective namespace: phenotypic_class def: "Phenotype that is a defect in response to pain (GO:0048265). 'response to pain' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.'" [FBC:DOS, GOC:jid, PMID:10203867, PMID:12723742, PMID:12843304, Wikipedia:Pain] subset: camcur is_a: FBcv:0000408 ! stress response defective [Term] id: FBcv:0000394 name: circadian rhythm defective namespace: phenotypic_class def: "Phenotype that is a defect in circadian rhythm (GO:0007623). 'circadian rhythm' is defined as: 'Any biological process in an organism that recurs with a regularity of approximately 24 hours.'" [FBC:DOS, GOC:bf, GOC:go_curators] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000395 name: locomotor rhythm defective namespace: phenotypic_class def: "Phenotype that is a defect in locomotor rhythm (GO:0045475). 'locomotor rhythm' is defined as: 'The rhythm of the locomotor activity of an organism during its 24 hour activity cycle..'" [FBC:DOS, GOC:go_curators] subset: camcur is_a: FBcv:0000414 ! locomotor behavior defective is_a: FBcv:0000679 ! circadian behavior defective [Term] id: FBcv:0000396 name: eclosion rhythm defective namespace: phenotypic_class def: "Phenotype that is a defect in eclosion rhythm (GO:0008062). 'eclosion rhythm' is defined as: 'The timing of the emergence of the adult fly from its pupal case, which usually occurs at dawn.'" [FBC:DOS, PMID:11715043] subset: camcur is_a: FBcv:0000670 ! eclosion defective is_a: FBcv:0000679 ! circadian behavior defective [Term] id: FBcv:0000397 name: learning defective namespace: phenotypic_class def: "Phenotype that is a defect in learning (GO:0007612). 'learning' is defined as: 'Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.'" [FBC:DOS, ISBN:0582227089, ISBN:0721662544] subset: camcur is_a: FBcv:0000387 ! behavior defective [Term] id: FBcv:0000398 name: memory defective namespace: phenotypic_class def: "Phenotype that is a defect in memory (GO:0007613). 'memory' is defined as: 'The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).'" [FBC:DOS, GOC:curators, http://www.onelook.com/, ISBN:0582227089] subset: camcur is_a: FBcv:0000387 ! behavior defective [Term] id: FBcv:0000399 name: courtship behavior defective namespace: phenotypic_class def: "Phenotype that is a defect in courtship behavior (GO:0007619). 'courtship behavior' is defined as: 'The behavioral interactions between organisms for the purpose of attracting sexual partners.'" [FBC:DOS, GOC:ai, GOC:dph] subset: camcur is_a: FBcv:0000721 ! mating behavior defective [Term] id: FBcv:0000400 name: mating defective namespace: phenotypic_class def: "Phenotype that is a defect in mating (GO:0007618). 'mating' is defined as: 'The pairwise union of individuals for the purpose of sexual reproduction, ultimately resulting in the formation of zygotes.'" [FBC:DOS, GOC:jl, ISBN:0387520546] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000401 name: mating rhythm defective namespace: phenotypic_class def: "Phenotype that is a defect in circadian mating behavior (GO:0035648). 'circadian mating behavior' is defined as: 'The fluctuation in mating behavior that occurs over an approximately 24 hour cycle.'" [FBC:DOS, GOC:bf, GOC:dos, PMID:11470898, PMID:17276917] subset: camcur is_a: FBcv:0000679 ! circadian behavior defective is_a: FBcv:0000721 ! mating behavior defective [Term] id: FBcv:0000402 name: song defective namespace: phenotypic_class def: "Phenotype that is a defect in male courtship behavior, veined wing generated song production (GO:0045433). This is defined as 'The process during wing vibration where the male insect produces a species-specific acoustic signal called a love song.'" [FBC:DOS, GOC:mtg_sensu, PMID:11092827] subset: camcur synonym: "singing defective" EXACT [FBC:SM] synonym: "song production defective" EXACT [FBC:SM] is_a: FBcv:0000399 ! courtship behavior defective [Term] id: FBcv:0000403 name: chemosensitive behavior defective namespace: phenotypic_class def: "Phenotype that is a defect in chemosensory behavior (GO:0007635). 'chemosensory behavior' is defined as: 'Behavior that is dependent upon the sensation of chemicals.'.'" [FBC:DOS, GOC:go_curators] subset: camcur synonym: "chemosensitive behaviour defective" EXACT [] is_a: FBcv:0000387 ! behavior defective [Term] id: FBcv:0000404 name: smell perception defective namespace: phenotypic_class def: "Phenotype that is a defect in sensory perception of smell (GO:0007608). 'sensory perception of smell'q: 'The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process.'" [FBC:DOS, GOC:ai, http://www.onelook.com/] subset: camcur synonym: "olfaction defective" EXACT [] is_a: FBcv:0000681 ! sensory perception defective [Term] id: FBcv:0000405 name: taste perception defective namespace: phenotypic_class def: "Phenotype that is a defect in sensory perception of taste (GO:0050909). 'sensory perception of taste' is defined as: 'The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process.'" [FBC:DOS, GOC:ai, http://www.onelook.com/] subset: camcur synonym: "gustation defective" EXACT [] synonym: "taste defective" EXACT [] is_a: FBcv:0000681 ! sensory perception defective [Term] id: FBcv:0000406 name: tarsal response defective namespace: phenotypic_class def: "Phenotype that is a failure to exhibit proboscis extension reflex in response to a sugar stimulus via taste sensilla on the tarsus." [FBC:DOS] subset: camcur is_a: FBcv:0000680 ! proboscis extension reflex defective [Term] id: FBcv:0000407 name: auditory perception defective namespace: phenotypic_class def: "Phenotype that is a defect in sensory perception of sound (GO:0007605). 'sensory perception of sound' is defined as: 'The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.'" [FBC:DOS, GOC:ai] subset: camcur synonym: "auditory system defective" RELATED [] is_a: FBcv:0000681 ! sensory perception defective [Term] id: FBcv:0000408 name: stress response defective namespace: phenotypic_class def: "Phenotype that is a defect in response to stress (GO:0006950). 'response to stress' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).'" [FBC:DOS, GOC:mah] subset: camcur synonym: "environmental stress response defective" NARROW [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000409 name: osmotic stress response defective namespace: phenotypic_class def: "Phenotype that is a defect in response to osmotic stress (GO:0006970). 'response to osmotic stress' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.'" [FBC:DOS, GOC:jl] subset: camcur is_a: FBcv:0000408 ! stress response defective [Term] id: FBcv:0000410 name: heat stress response defective namespace: phenotypic_class def: "Phenotype that is a defect in response to heat (GO:0009408). 'response to heat' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.'" [FBC:DOS, GOC:lr] subset: camcur is_a: FBcv:0000408 ! stress response defective is_a: FBcv:0000683 ! temperature response defective [Term] id: FBcv:0000411 name: visual behavior defective namespace: phenotypic_class def: "Phenotype that is a defect in visual behavior (GO:0007632). 'visual behavior' is defined as: 'The behavior of an organism in response to a visual stimulus.'" [FBC:DOS, GOC:jid, GOC:pr] subset: camcur synonym: "visual behaviour defective" EXACT [] is_a: FBcv:0000387 ! behavior defective [Term] id: FBcv:0000412 name: optomotor response defective namespace: phenotypic_class def: "Phenotype that is a defect in optomotor response: a motor response during flight or walking that serves to stabilize both image formation on the retina and locomotor course." [FBC:DOS] subset: camcur synonym: "optomotor behaviour defective" EXACT [] is_a: FBcv:0000411 ! visual behavior defective [Term] id: FBcv:0000413 name: phototaxis defective namespace: phenotypic_class def: "Phenotype that is a defect in phototaxis (GO:0042331). 'phototaxis' is defined as: 'The directed movement of a motile cell or organism in response to light.'" [FBC:DOS, GOC:jl, ISBN:0192800981] subset: camcur synonym: "phototaxis behaviour defective" RELATED [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000414 name: locomotor behavior defective namespace: phenotypic_class def: "Phenotype that is a defect in locomotory behavior (GO:0007626). 'locomotory behavior' is defined as: 'The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.'" [FBC:DOS, GOC:dph] subset: camcur synonym: "locomotor behaviour defective" EXACT [] is_a: FBcv:0000387 ! behavior defective [Term] id: FBcv:0000415 name: jumping defective namespace: phenotypic_class def: "Phenotype that is a reduced ability to jump or a reduced jump response. This may be due to neurological or muscular defects." [FBC:DOS] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000416 name: uncoordinated namespace: phenotypic_class def: "Phenotype that is a lack of normal co-ordination in locomotor activity." [FBC:DOS] subset: camcur is_a: FBcv:0000414 ! locomotor behavior defective [Term] id: FBcv:0000417 name: flight defective namespace: phenotypic_class def: "Phenotype that is a defect in flight (GO:0060361). 'flight' is defined as: 'Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement.'" [FBC:DOS, GOC:dph] comment: This term is agnostic as to the causes of defects in flight. An animal's flight may be defective for mechanical, behavioral or sensory reasons. subset: camcur synonym: "flight behaviour defective" NARROW [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000418 name: flightless namespace: phenotypic_class def: "Phenotype that is the absence of flight (GO:0060361). 'flight' is defined as: 'Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement.'" [FBC:DOS, GOC:dph] comment: This term is agnostic as to the causes of flightlessness. An animal may be flightless for mechanical or behavioral reasons. subset: camcur is_a: FBcv:0000417 ! flight defective [Term] id: FBcv:0000419 name: feeding behavior defective namespace: phenotypic_class def: "Phenotype that is a defect in feeding behavior (GO:0007631). 'feeding behavior' is defined as: 'Behavior associated with the intake of food.'" [FBC:DOS, GOC:mah] subset: camcur synonym: "feeding behaviour defective" EXACT [] is_a: FBcv:0000387 ! behavior defective [Term] id: FBcv:0000420 name: grooming behavior defective namespace: phenotypic_class def: "Phenotype that is a defect in grooming behavior (GO:0007625). 'grooming behavior' is defined as: 'The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites.'" [FBC:DOS, GOC:jl, GOC:pr] subset: camcur synonym: "grooming behaviour defective" EXACT [] is_a: FBcv:0000387 ! behavior defective [Term] id: FBcv:0000421 name: touch sensitivity defective namespace: phenotypic_class def: "Phenotype that is reduction in or loss of a stereotypical locomotory response to touch." [FlyBase:FBrf0073546] comment: This phenotype is commonly assayed by scoring larval avoidance responses following stroking of the thoracic segments (see Kernan et al., 1994). On its own, this is not sufficient evidence for a defect in sensory perception of touch, as motor defects can also cause this phenotype. Internal note - subset: camcur is_a: FBcv:0000387 ! behavior defective [Term] id: FBcv:0000422 name: photoperiod response variant namespace: phenotypic_class def: "Phenotype that is a defect in entrainment of circadian clock by photoperiod (GO:0043153), which is defined as: 'The synchronization of a circadian rhythm to photoperiod, the intermittent cycle of light (day) and dark (night).'" [FBC:DOS, GOC:jl] subset: camcur is_a: FBcv:0000387 ! behavior defective [Term] id: FBcv:0000423 name: DNA repair defective namespace: phenotypic_class def: "Phenotype that is a defect in DNA repair (GO:0006281). 'DNA repair' is defined as: 'The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.'" [FBC:DOS, PMID:11563486] subset: camcur is_a: FBcv:0000408 ! stress response defective [Term] id: FBcv:0000424 name: cell death defective namespace: phenotypic_class def: "Phenotype that is a change in the amount of cell death in a whole animal or in some specific organ tissue or clone of cells compared to wild-type. This may be due to effects on the regulation of cell death (GO:0010941) or in cell death (GO:0008219) pathways themselves." [FBC:DOS] subset: camcur synonym: "apoptosis defective" NARROW [] synonym: "pcd defective" NARROW [] synonym: "programmed cell death defective" NARROW [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000425 name: increased cell death namespace: phenotypic_class def: "Phenotype that is an increase in the amount of cell death in a whole animal or in some specific organ tissue or clone of cells compared to wild-type." [FBC:DOS] subset: camcur synonym: "pcd increase" NARROW [] synonym: "programmed cell death increase" NARROW [] is_a: FBcv:0000424 ! cell death defective [Term] id: FBcv:0000426 name: decreased cell death namespace: phenotypic_class def: "Phenotype that is an increase in the amount of cell death in a whole animal or in some specific organ tissue or clone of cells compared to wild-type." [FBC:DOS] subset: camcur synonym: "pcd decrease" NARROW [] synonym: "programmed cell death decrease" NARROW [] is_a: FBcv:0000424 ! cell death defective [Term] id: FBcv:0000427 name: cell growth defective namespace: phenotypic_class def: "Phenotype that is a defect in cell growth (GO:0016049). 'cell growth' is defined as: 'The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.'" [FBC:DOS, GOC:ai] comment: Note that defects in cell size are not necessarily the result of defects in cell growth. A change in the rate of cell division in the absence of any change in cell growth rate can result in smaller or larger cells. subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000428 name: cell size defective namespace: phenotypic_class def: "Phenotype that is a defect in the size of cells in a whole animal or in some specific organ, tissue or clone of cells compared to wild-type." [FBC:DOS] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000429 name: cell shape defective namespace: phenotypic_class def: "Phenotype that is a defect in the shape (PATO:0000052) of some cell compared to wild-type." [FBC:DOS] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000430 name: cell polarity defective namespace: phenotypic_class def: "Phenotype that is a defect in the asymmetric distribution of components within a cell. For example an epithelial cell is 'cell polarity defective' if it lacks the normal asymmetric distribution of proteins or cell components such as junctions or villi along its apical-basal axis." [FBC:DOS] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000431 name: meiotic cell cycle defective namespace: phenotypic_class def: "Phenotype that is a defect in meiotic cell cycle (GO:0051321). 'meiotic cell cycle' is defined as: 'Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.'" [FBC:DOS, GOC:ai] subset: camcur synonym: "meiotic" RELATED [] is_a: FBcv:0000671 ! cell cycle defective [Term] id: FBcv:0000432 name: mitotic cell cycle defective namespace: phenotypic_class def: "Phenotype that is a defect in mitotic cell cycle (GO:0000278). 'mitotic cell cycle' is defined as: 'Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.'" [FBC:DOS, GOC:mah, ISBN:0815316194, Reactome:69278] subset: camcur synonym: "mitotic" RELATED [] is_a: FBcv:0000671 ! cell cycle defective [Term] id: FBcv:0000433 name: cytokinesis defective namespace: phenotypic_class def: "Phenotype that is a defect in cytokinesis (GO:0000910). 'cytokinesis' is defined as: 'The division of the cytoplasm and the plasma membrane of a cell and its separation into two daughter cells.'" [FBC:DOS, GOC:mtg_cell_cycle] subset: camcur is_a: FBcv:0000671 ! cell cycle defective [Term] id: FBcv:0000434 name: neurophysiology defective namespace: phenotypic_class def: "Phenotype that is a defect in the electrophysiological properties of some class of neurons, muscles or anatomical structure of the nervous system. Examples of these phenotypes at the neuron class level include defects in spontaneous or evoked excitatory junction potential. Examples at a more gross anatomical level include abnormal retinal electrophysiology (e.g.- measured by an electroretinogram)." [FBC:DOS] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000435 name: neuroanatomy defective namespace: phenotypic_class def: "Phenotype that is a defect in nervous system (FBbt:00005093). 'nervous system' is defined as: 'All the nerve centers and nerve fibers in the central, visceral and peripheral nervous systems.'" [FBC:DOS, ISBN:978-3-11-014898-5] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000436 name: sex-determination defective namespace: phenotypic_class def: "Phenotype that is a defect in sex determination (GO:0007530). 'sex determination' is defined as: 'Any process that establishes and transmits the specification of sexual status of an individual organism.'" [FBC:DOS, ISBN:0198506732] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000437 name: dosage compensation defective namespace: phenotypic_class def: "Phenotype that is a defect in dosage compensation (GO:0007549). 'dosage compensation' is defined as: 'Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by a global activation or inactivation of all, or most of, genes on one or both of the X chromosomes.'" [FBC:DOS, GOC:ems, ISBN:0140512888, PMID:11498577] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000438 name: electrophoretic variant namespace: phenotypic_class def: "Phenotype that is a difference in electrophoretic migration of a gene product compared to wild-type." [FBC:DOS] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000439 name: chemical resistant namespace: phenotypic_class def: "Phenotype that is a decreased sensitivity (compared to wild-type) to the toxic effects of some specified chemical. The phrase 'toxic effects' here refers to reversible effects such as inebriation and sedation as well as sustained damage, developmental defects and death." [FBC:DOS] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000440 name: chemical sensitive namespace: phenotypic_class def: "Phenotype that is an increased sensitivity (compared to wild-type) to the toxic effects of some specified chemical. The phrase 'toxic effects' here refers to reversible effects such as inebriation and sedation as well as sustained damage, developmental defects and death." [FBC:DOS] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000441 name: radiation resistant namespace: phenotypic_class def: "Phenotype that is a decreased tendency for radiation exposure to cause toxic effects." [FBC:DOS] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000442 name: radiation sensitive namespace: phenotypic_class def: "Phenotype that is an increased tendency for radiation exposure to cause toxic effects." [FBC:DOS] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000443 name: Minute namespace: phenotypic_class def: "Dominant phenotype consisting of short slender bristles and delayed development. Homozygotes are cell lethal." [FlyBase:FBrf0066905] comment: The phenotype may be a general result of mutations in essential components of the protein synthesis pathyway, as a number of Minutes encode ribosomal proteins. In an animal that is heterozygous for a Minute mutation, cells with two wild-type alleles of the affected gene have a growth advantage. Many developmental studies take advantage of this fact to give somatic clones a growth advantage. The term 'Minute' should not be used to annotate the resulting phenotypes. subset: camcur is_a: FBcv:0000450 ! developmental rate defective [Term] id: FBcv:0000444 name: hyperplasia namespace: phenotypic_class def: "Phenotype that is an increase in size of a tissue or organ due to increased numbers of cells, where the affected tissue or organ maintains its normal form." [ISBN:9780198506737] subset: camcur synonym: "hyperplastic" EXACT [] is_a: FBcv:0000357 ! size defective is_a: FBcv:0000362 ! increased cell number [Term] id: FBcv:0000445 name: tumorigenic namespace: phenotypic_class def: "Phenotype that is characterised by the formation of abnormal masses of tissue (tumors) as the result of neoplasia." [FBC:DOS] subset: camcur is_a: FBcv:0000723 ! neoplasia [Term] id: FBcv:0000446 name: melanotic mass phenotype namespace: phenotypic_class def: "Phenotype characterised by the formation of lumps of melanotic tissue inside the body in the absence of foreign bodies." [FlyBase:FBrf0094387, FlyBase:FBrf0194475] comment: Melanotic capsules are formed around foreign bodies in wild-type animals as part of the immune response, for example as a protection against parasitoid wasps. Some, but not all melanotic mass phenotypes involve ectopic activation of this immmune response. While melanotic masses are commonly referred to as melanotic tumors in the historical listerature, this is a misnomer as they are rarely neoplastic. subset: camcur synonym: "melanotic 'tumor'" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000447 name: melanotic necrosis namespace: phenotypic_class def: "Phenotype characterised by closely associated necrosis and melanisation." [FlyBase:FBrf0155704] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000448 name: immune response defective namespace: phenotypic_class def: "Phenotype that is a defect in immune response (GO:0006955). 'immune response' is defined as: 'Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.'" [FBC:DOS, GO_REF:0000022, GOC:add, GOC:mtg_15nov05] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000449 name: planar polarity defective namespace: phenotypic_class def: "Phenotype that is a defect in establishment of planar polarity (GO:0001736). 'establishment of planar polarity' is defined as: 'Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates.'" [GOC:dph] comment: For apical-basal polarity phenotypes of epithelia, the appropriate term is 'cell polarity defective'. subset: camcur synonym: "tissue polarity defective" BROAD [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000450 name: developmental rate defective namespace: phenotypic_class def: "Phenotype that is a change in the rate of some developmental process (GO:0032502) taking place prior to mature adulthood (defined as adult stage A3), compared to wild-type. Note, developmental processes include stages in development of the whole animal (e.g.- larval development) as well as specific sub-processes, such as dorsal closure." [FBC:DOS] comment: A more complete formalisation would require a clause specifying stage. It might be possible to do this in OWL using the same system as we are using for lethal phase. subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000451 name: wound healing defective namespace: phenotypic_class def: "Phenotype that is a defect in wound healing (GO:0042060). 'wound healing' is defined as: 'The series of events that restore integrity to a damaged tissue, following an injury.'" [GOC:bf, PMID:15269788] subset: camcur is_a: FBcv:0000408 ! stress response defective [Term] id: FBcv:0000452 name: origin of mutation namespace: origin_of_mutation is_a: FBcv:0000807 ! allele descriptor [Term] id: FBcv:0000453 name: piggyBac ammunition for transposable element mutagenesis is_obsolete: true [Term] id: FBcv:0000454 name: synthetic namespace: origin_of_mutation is_obsolete: true consider: FBcv:0000455 [Term] id: FBcv:0000455 name: in vitro construct namespace: origin_of_mutation def: "DNA change introduced by using an in vitro construct. The sequence of the in vitro construct determines the type of change." [FBC:MC] subset: camcur synonym: "change induced by in vitro construct" EXACT [] is_a: FBcv:0000452 ! origin of mutation [Term] id: FBcv:0000456 name: in vitro construct - regulatory fusion namespace: origin_of_mutation def: "Sequence change introduced by using an in vitro construct that contains a fusion of the regulatory region of one gene on to the coding region of another. Examples in FlyBase include heat shock constructs, FRT flip out constructs and reporter genes." [FBC:DOS] comment: Notes on usage: Use this, rather than 'in vitro construct - deletion', for families of promoter deletions. Thus, a family of deletions of eve promoters driving Ecol\\\\lacZ will have regulatory fusion, but not deletion, as their mutagen. subset: camcur synonym: "change induced by an in vitro construct - regulatory fusion" EXACT [] synonym: "in vitro construct | regulatory fusion" RELATED [] is_a: FBcv:0000455 ! in vitro construct [Term] id: FBcv:0000457 name: in vitro construct - coding region fusion namespace: origin_of_mutation def: "Sequence change introduced by using an in vitro construct that contains a in-frame fusion of the open reading frames from two or more genes. In FlyBase, the resulting genes may be classified as fusion genes or tagged genes." [FBC:DOS] subset: camcur synonym: "change induced by an in vitro construct - coding region fusion" EXACT [] synonym: "in vitro construct | coding region fusion" RELATED [] is_a: FBcv:0000455 ! in vitro construct [Term] id: FBcv:0000458 name: in vitro construct - site directed mutagenesis namespace: origin_of_mutation def: "Mutation induced by an in vitro construct that uses site directed mutagenesis to target a particular region of the gene." [FBC:DOS] subset: camcur synonym: "in vitro construct | site directed mutagenesis" RELATED [] synonym: "mutation induced by an in vitro construct - site directed mutagenesis" EXACT [] is_a: FBcv:0000455 ! in vitro construct [Term] id: FBcv:0000459 name: in vitro construct - deletion namespace: origin_of_mutation def: "Sequence change introduced by an in vitro construct generated by internal deletion of some genomic sequence or cDNA." [FBC:DOS] subset: camcur synonym: "change induced by an in vitro construct - deletion" EXACT [] synonym: "in vitro construct | deletion" RELATED [] is_a: FBcv:0000455 ! in vitro construct [Term] id: FBcv:0000460 name: in vitro construct - genomic fragment namespace: origin_of_mutation def: "Sequence change introduced by an in vitro construct containing a genomic fragment that partially or fully rescues loss of function mutations or deletions of the gene whose sequence it carries." [FBC:DOS] comment: Notes on usage: 1. This term is applicable whether or not rescue using the construct is complete. 2. When a smaller rescue fragment is derived from a larger, by deletion of one or both ends, the mutagen shall be 'in vitro construct | deletion', with the larger being stated as the progenitor allele. subset: camcur synonym: "change induced by an in vitro construct - genomic fragment" EXACT [] synonym: "in vitro construct | genomic fragment" RELATED [] is_a: FBcv:0000455 ! in vitro construct [Term] id: FBcv:0000461 name: in vitro construct - minigene namespace: origin_of_mutation def: "Sequence change introduced by an in vitro construct that contains the wild-type open reading frame of a gene (without introns), the expression of which is controlled by a wild-type promoter of the same gene. Such constructs are often generated by fusing a cDNA to a genomic region containing promoter sequences, or more rarely by deletion of introns and other non-essential sequences from a genomic region, leaving a wild type coding region and promoter intact." [FBC:DOS] subset: camcur synonym: "change induced by an in vitro construct - minigene" EXACT [] synonym: "in vitro construct | minigene" RELATED [] is_a: FBcv:0000455 ! in vitro construct [Term] id: FBcv:0000462 name: in vitro construct - amino acid replacement namespace: origin_of_mutation def: "Sequence change introduced by an in vitro construct that uses site directed mutagenesis to target a particular region of the gene resulting in a change to the change to the amino acids sequence encodes.." [FBC:DOS] subset: camcur synonym: "change induced by an in vitro construct - amino acid replacement" EXACT [] synonym: "in vitro construct | amino acid replacement" RELATED [] is_a: FBcv:0000458 ! in vitro construct - site directed mutagenesis [Term] id: FBcv:0000463 name: in vitro construct - RNAi namespace: origin_of_mutation def: "Sequence change introduced by an in vitro construct designed to generate dsRNA for RNA interference (RNAi) experiments." [FBC:DOS] subset: camcur synonym: "change induced by an in vitro construct - RNAi" EXACT [] synonym: "in vitro construct | RNAi" RELATED [] is_a: FBcv:0000455 ! in vitro construct [Term] id: FBcv:0000464 name: in vitro construct - other namespace: origin_of_mutation subset: camcur synonym: "in vitro construct | other" EXACT [] is_obsolete: true consider: FBcv:0000455 [Term] id: FBcv:0000465 name: natural population namespace: origin_of_mutation subset: camcur is_a: FBcv:0000452 ! origin of mutation [Term] id: FBcv:0000466 name: temperature namespace: origin_of_mutation def: "Mutation caused by exposure to a temperature that is higher or lower than 25 degrees Celsius." [FBC:MC] subset: camcur synonym: "environmental treatment" RELATED [] synonym: "mutation induced by temperature treatment" EXACT [] is_a: FBcv:0000452 ! origin of mutation [Term] id: FBcv:0000467 name: cold namespace: origin_of_mutation def: "Mutation induced by exposure to temperature that is lower than 25 degrees Celsius." [FBC:MC] subset: camcur synonym: "cold-treatment" RELATED [] synonym: "mutation induced by cold treatment" EXACT [] is_a: FBcv:0000466 ! temperature [Term] id: FBcv:0000468 name: heat namespace: origin_of_mutation def: "Mutation induced by exposure to a temperature that is higher than 25 degrees Celsius." [FBC:MC] subset: camcur synonym: "heat-treatment" RELATED [] synonym: "mutation induced by heat treatment" EXACT [] is_a: FBcv:0000466 ! temperature [Term] id: FBcv:0000469 name: spontaneous namespace: origin_of_mutation def: "Mutation caused by a spontaneous event." [FBC:MC] subset: camcur synonym: "mutation induced by spontaneous event" EXACT [] is_a: FBcv:0000452 ! origin of mutation [Term] id: FBcv:0000470 name: recombination namespace: origin_of_mutation def: "Sequence change induced by the genetic exchange that takes place between DNA sequences." [FBC:MC, ISBN:978-0-8153-3218-3] subset: camcur synonym: "change induced by recombination" EXACT [] is_a: FBcv:0000452 ! origin of mutation [Term] id: FBcv:0000471 name: gene conversion namespace: origin_of_mutation def: "Sequence change caused by a DNA recombination process that results in the unidirectional transfer of genetic material from a donor sequence to a highly homologous acceptor (GO:0035822)." [PMID:17846636] comment: Strictly, gene conversion (GO:0035822) defines only the endogenous process, not its use for engineered gene targeting. subset: camcur synonym: "change induced by gene conversion" EXACT [] is_a: FBcv:0000470 ! recombination [Term] id: FBcv:0000472 name: intralocus exchange namespace: origin_of_mutation def: "Mutation caused by a recombination event that causes the unequal exchange of small intralocus regions, usually leading to the formation of duplication and deficiency products." [FBC:MC, FlyBase:FBrf0014117, FlyBase:FBrf0202435] subset: camcur synonym: "mutation induced by intralocus exchange" EXACT [] is_a: FBcv:0000470 ! recombination [Term] id: FBcv:0000473 name: unequal recombination namespace: origin_of_mutation def: "Sequence change caused by a recombination event that causes an unequal exchange of genetic material between homologous or non-homologous regions." [FlyBase:FBrf0202435] subset: camcur synonym: "change induced by unequal recombination" EXACT [] is_a: FBcv:0000470 ! recombination [Term] id: FBcv:0000474 name: mitotic recombination namespace: origin_of_mutation def: "Sequence change caused by the exchange of genetic material during mitosis that occurs at crossing over, and more frequently between homologous chromosomes." [FlyBase:FBrf0202435] subset: camcur synonym: "change induced by mitotic recombination" EXACT [] is_a: FBcv:0000470 ! recombination [Term] id: FBcv:0000475 name: magnification namespace: origin_of_mutation def: "Sequence change caused by a recombination event between tandem repeats of rRNA genes that causes unequal chromatid exchange at crossing over and an increase in the number of functional copies. It causes a reversion from mutant to wild-type phenotype." [FlyBase:FBrf0202435, FlyBase:FBrf0218934] subset: camcur synonym: "mutation induced by magnification" EXACT [] is_a: FBcv:0000470 ! recombination [Term] id: FBcv:0000476 name: detachment namespace: origin_of_mutation def: "Mutation that is caused by a recombination event that causes the breakdown of compound chromosome arms resulting in duplications or deletions in proximal regions." [FBC:MC, FlyBase:FBrf0202435] subset: camcur synonym: "mutation induced by detachment" EXACT [] is_a: FBcv:0000470 ! recombination [Term] id: FBcv:0000477 name: reduction namespace: origin_of_mutation def: "Mutation caused by a recombination event between tandem repeats of rRNA genes that causes unequal chromatid exchange at crossing over and a reduction in the number of functional copies. It leads to an aggravation of phenotype, in the case of a mutation causing a change from a wildtype to mutant phenotype or a change from a mutant to a more severe mutant phenotype." [FlyBase:FBrf0026874] subset: camcur synonym: "mutation induced by reduction" EXACT [] is_a: FBcv:0000470 ! recombination [Term] id: FBcv:0000478 name: site specific recombination namespace: origin_of_mutation def: "Sequence change induced by a recombination event catalyzed by a recombinase that occurs at specific nucleotide sequences." [FlyBase:FBrf0202435, ISBN:978-0-8153-3218-3] subset: camcur synonym: "change induced by site specific recombination" EXACT [] is_a: FBcv:0000470 ! recombination [Term] id: FBcv:0000479 name: FLPase namespace: origin_of_mutation def: "Sequence change caused by a site specific recombination event catalyzed by the tyrosine recombinase FLPase, that recognises minimal FLP recombination target (FRT) sites of 34 base pairs. For site specific integration, the recombination site consists of 48 base pairs containing an additional isolated base pair and a third 13 base pair direct repeat." [FlyBase:FBrf0201927, UniProt:P03870] subset: camcur synonym: "change induced by FLPase recombination" EXACT [] is_a: FBcv:0000478 ! site specific recombination [Term] id: FBcv:0000480 name: I-SceI namespace: origin_of_mutation def: "Sequence change caused by the cleavage of an 18 base pair DNA sequence by the I-SceI endonuclease." [FlyBase:FBrf0128625, UniProt:P03882] subset: camcur synonym: "change induced by I-SceI endonuclease cleavage" EXACT [] synonym: "SCEI endonuclease" RELATED [] is_a: FBcv:0003007 ! site specific cleavage [Term] id: FBcv:0000481 name: cre recombinase namespace: origin_of_mutation def: "Sequence change induced by a site specific recombination event catalyzed by the tyrosine recombinase cre. Recombination is induced between two 34 base pairs loxP sites. These consist of two 13 base pair perfect inverted repeats flanking an 8 base pair asymmetric spacer that confers directionality." [FlyBase:FBrf0201927, PMID:6954485, UniProt:P06956] subset: camcur synonym: "change induced by cre recombinase recombination" EXACT [] synonym: "Cre recombinase" RELATED [] is_a: FBcv:0000478 ! site specific recombination [Term] id: FBcv:0000482 name: segregation namespace: origin_of_mutation def: "Sequence change induced by chromosomal segregation." [FBC:MC] subset: camcur synonym: "change induced by segregation" EXACT [] is_a: FBcv:0000452 ! origin of mutation [Term] id: FBcv:0000483 name: transposable element activity namespace: origin_of_mutation def: "Mutation induced by the mobilization of a transposable element." [FBC:MC, FlyBase:FBrf0202435] subset: camcur synonym: "mutation induced by transposable element activity" EXACT [] is_a: FBcv:0000452 ! origin of mutation [Term] id: FBcv:0000484 name: IR-hybrid dysgenesis namespace: origin_of_mutation def: "Mutation caused by hybrid dysgenesis that results from the mobilization of the I-element retrotransposon." [FlyBase:FBrf0202435] subset: camcur synonym: "IR" RELATED [] synonym: "mutation induced by IR-hybrid dysgenesis" EXACT [] is_a: FBcv:0003019 ! I-element activity [Term] id: FBcv:0000485 name: Stalker-hybrid dysgenesis namespace: origin_of_mutation def: "Mutation induced by hybrid dysgenesis caused by the mobilization of the Stalker transposable element." [FlyBase:FBrf0202435] subset: camcur synonym: "mutation induced by Stalker-hybrid dysgenesis" EXACT [] is_a: FBcv:0003020 ! Stalker element activity [Term] id: FBcv:0000486 name: P-element activity namespace: origin_of_mutation def: "Mutation induced by the transposable activity caused by a P-element, a DNA transposable element. The P-element is 2.9 kilobases in length with 31 base pairs inverted terminal repeats. Upon insertion it generates a flanking duplication of 8 base pairs at the target site upon insertion. Mobilization is induced by the activity of a P-element transposase." [FlyBase:FBrf0202435] subset: camcur synonym: "mutation induced by P-element activity" EXACT [] is_a: FBcv:0000483 ! transposable element activity [Term] id: FBcv:0000487 name: PM hybrid dysgenesis namespace: origin_of_mutation def: "Mutation caused by hybrid dysgenesis that results from the action of the P-element." [FlyBase:FBrf0202435] subset: camcur synonym: "mutation induced by PM hybrid dysgenesis" EXACT [] is_a: FBcv:0000486 ! P-element activity [Term] id: FBcv:0000488 name: Delta2-3 transposase namespace: origin_of_mutation def: "Mutation induced by the mobilization of a P-element by the Delta2-3 transposase. The source of Delta2-3 is a stable genomic integration from which the third intron has been deleted." [FlyBase:FBrf0202435] subset: camcur synonym: "&Dgr;2-3" RELATED [] synonym: "mutation induced by P-element mobilization by Delta2-3 transposase" EXACT [] is_a: FBcv:0000486 ! P-element activity [Term] id: FBcv:0000489 name: jumpstarter activity namespace: origin_of_mutation def: "Mutation caused by a P-element that is inserted into the genome and that is used to create more insertions at other sites." [FlyBase:FBrf0202435] subset: camcur synonym: "Js" RELATED [] synonym: "Jumpstarter" RELATED [] synonym: "mutation induced by jumpstarter mobilization" EXACT [] is_a: FBcv:0000486 ! P-element activity [Term] id: FBcv:0000490 name: p pi25.1 supplied transposase namespace: origin_of_mutation def: "Mutation caused by the mobilization of a P-element by the transposase produced from the helper plasmid p pi25.1. This plasmid is a P-element from which the 3' terminus has been deleted, making it unable to integrate into the host's DNA. It is missing a 23 base pairs deletion of the 3' terminus compared to p pi25.1wc." [FlyBase:FBrf0202435] subset: camcur synonym: "mutation induced by P-element mobilization by p pi25.1 supplied transposase" EXACT [] synonym: "p pi25.1" RELATED [] synonym: "p&pgr;25.1" RELATED [] is_a: FBcv:0000486 ! P-element activity [Term] id: FBcv:0000491 name: p pi25.7wc namespace: origin_of_mutation def: "Mutation caused by the mobilization of a P-element by the transposase produced from the helper plasmid p pi25.7wc. This plasmid is a P-element from which the 3' terminus has been deleted, making it unable to integrate into the host's DNA. It has an additional 23 base pairs deletion of the 3' terminus compared to p pi25.1." [FlyBase:FBrf0202435] subset: camcur synonym: "mutation induced by P-element mobilization by p pi25.7wc supplied transposase" EXACT [] synonym: "p pi25.7wc" RELATED [] synonym: "p&pgr;25.7wc" RELATED [] is_a: FBcv:0000486 ! P-element activity [Term] id: FBcv:0000492 name: male recombination induced by dysgenesis namespace: origin_of_mutation def: "Mutation caused by PM hybrid dysgenesis that is induced by the higher frequency of recombination in certain male chromosomes." [FlyBase:FBrf0202435] subset: camcur synonym: "MR" RELATED [] synonym: "mutation induced by male recombination" EXACT [] is_a: FBcv:0000487 ! PM hybrid dysgenesis [Term] id: FBcv:0000493 name: MRh12 induced male recombination namespace: origin_of_mutation def: "Mutation caused by a male recombination event induced by a male recombination factor which is present in chromosomes extracted from a population in Haifa, Israel." [FlyBase:FBrf0202435] subset: camcur synonym: " MRh12" RELATED [] synonym: "mutation induced by MRh12 male recombination" EXACT [] is_a: FBcv:0000492 ! male recombination induced by dysgenesis [Term] id: FBcv:0000494 name: MRT007 induced male recombination namespace: origin_of_mutation def: "Mutation caused by a male recombination event in the second and third chromosomes induced by a male recombination factor which is present in chromosomes extracted from a population in Harlingen, Texas." [FlyBase:FBrf0202435] subset: camcur synonym: "MRT007" RELATED [] synonym: "mutation induced by MRT007 male recombination" EXACT [] is_a: FBcv:0000492 ! male recombination induced by dysgenesis [Term] id: FBcv:0000495 name: MRF23.5 induced male recombination namespace: origin_of_mutation def: "Mutation caused by a male recombination event induced by a male recombination factor which is present in chromosomes extracted from a population in Patras, Greece." [FlyBase:FBrf0202435] subset: camcur synonym: "MRF23.5" RELATED [] synonym: "mutation induced by MRF23.5 male recombination" EXACT [] is_a: FBcv:0000492 ! male recombination induced by dysgenesis [Term] id: FBcv:0000496 name: MRF31.1 induced male recombination namespace: origin_of_mutation def: "Mutation caused by a male recombination event induced by a male recombination factor which is present in chromosomes extracted from a population in Patras, Greece." [FlyBase:FBrf0202435] subset: camcur synonym: "MRF31.1" RELATED [] synonym: "mutation induced by MRF31.1 male recombination" EXACT [] is_a: FBcv:0000492 ! male recombination induced by dysgenesis [Term] id: FBcv:0000497 name: hobo activity namespace: origin_of_mutation def: "Mutation induced by the transposable activity caused by hobo, a DNA transposable element. The hobo element is 3.0 kilobases in length with 12 base pairs inverted terminal repeats. After mobilization by the hobo transposase and upon insertion it generates a flanking duplication of 8 base pairs at the target site upon insertion." [FlyBase:FBrf0202435] subset: camcur synonym: "mutation induced by hobo element activity" EXACT [] is_a: FBcv:0000483 ! transposable element activity [Term] id: FBcv:0000498 name: hobo dysgenesis namespace: origin_of_mutation def: "Mutation caused by hybrid dysgenesis that results from the mobilization of the hobo element." [FlyBase:FBrf0202435] subset: camcur synonym: "mutation induced by hobo dysgenesis" EXACT [] is_a: FBcv:0000497 ! hobo activity [Term] id: FBcv:0000499 name: HBL1 supplied transposase namespace: origin_of_mutation def: "Mutation caused by the activity of the hobo element, mobilized by an hobo transposase which is produced from the supplied P-element helper plasmid HBL1." [FlyBase:FBrf0202435] subset: camcur synonym: "Hobbled1" RELATED [] synonym: "Hobo transposase source" RELATED [] synonym: "mutation induced by Hobo transposase source HBL1" EXACT [] is_a: FBcv:0000497 ! hobo activity [Term] id: FBcv:0000500 name: mariner activity namespace: origin_of_mutation def: "Mutation induced by the transposable activity caused by mariner, a DNA transposable element. The mariner element is 1.3 kilobases in length with 28 base pairs inverted terminal repeats. It specifically targets TA dinucleotides and generates a flanking duplication of tehse two bases upon insertion. Mobilization is induced by the activity of the mariner transposase." [FlyBase:FBrf0202435] subset: camcur synonym: "mutation induced by mariner activity" EXACT [] is_a: FBcv:0000483 ! transposable element activity [Term] id: FBcv:0000501 name: gypsy element activity namespace: origin_of_mutation def: "Mutation induced by transposable activity caused by the gypsy retrovirus. The gypsy element is a 7.5 kilobases in length with 482 base pairs terminal repeats. Mobilization is induced by the activity of the gypsy element transposase." [FlyBase:FBrf0202435] subset: camcur synonym: "mutation induced by gypsy element activity" EXACT [] is_a: FBcv:0000483 ! transposable element activity [Term] id: FBcv:0000502 name: piggyBac activity namespace: origin_of_mutation def: "Mutation induced by the transposable activity caused by piggyBac, a DNA transposable element. The piggyBac is 2.5 kilobases in length with 13 base pairs inverted terminal repeats. It specifically targets TTAA dinucleotides and generates a flanking duplication of these 4 base pairs upon insertion. Mobilization is induced by the activity of the piggyBac transposase." [FlyBase:FBrf0202435] subset: camcur synonym: "mutation induced by piggyBac activity" EXACT [] is_a: FBcv:0000483 ! transposable element activity [Term] id: FBcv:0000503 name: irradiation namespace: origin_of_mutation def: "Mutation induced by exposure to radiation." [FBC:MC] subset: camcur synonym: "mutation induced by irradiation" EXACT [] is_a: FBcv:0000452 ! origin of mutation [Term] id: FBcv:0000504 name: ionizing radiation namespace: origin_of_mutation def: "Mutation induced by exposure to ionizing radiation." [FBC:MC] subset: camcur synonym: "mutation induced by ionizing irradiation" EXACT [] is_a: FBcv:0000503 ! irradiation [Term] id: FBcv:0000505 name: alpha ray namespace: origin_of_mutation def: "Mutation induced by exposure to alpha rays." [FBC:MC] subset: camcur synonym: "&agr; ray" RELATED [] synonym: "mutation induced by alpha ray irradiation" EXACT [] is_a: FBcv:0000504 ! ionizing radiation [Term] id: FBcv:0000506 name: gamma ray namespace: origin_of_mutation def: "Mutation induced by exposure to gamma rays." [FBC:MC] subset: camcur synonym: "&ggr; ray" RELATED [] synonym: "mutation induced by gamma ray irradiation" EXACT [] is_a: FBcv:0000504 ! ionizing radiation [Term] id: FBcv:0000507 name: 60Co gamma ray namespace: origin_of_mutation def: "Mutation induced by exposure to 60Co gamma rays." [FBC:MC] subset: camcur synonym: "60Co &ggr; ray" RELATED [] synonym: "mutation induced by 60Co gamma ray irradiation" EXACT [] is_a: FBcv:0000506 ! gamma ray [Term] id: FBcv:0000508 name: 137Cs gamma ray namespace: origin_of_mutation def: "Mutation induced by exposure to 137Cs gamma rays." [FBC:MC] subset: camcur synonym: "137Cs &ggr; ray" RELATED [] synonym: "mutation induced by 137Cs gamma ray irradiation" EXACT [] is_a: FBcv:0000506 ! gamma ray [Term] id: FBcv:0000509 name: 226Ra alpha ray namespace: origin_of_mutation def: "Mutation induced by exposure to 226Ra alpha rays." [FBC:MC] subset: camcur synonym: "226Ra &agr; ray" RELATED [] synonym: "mutation induced by 226Ra alpha ray irradiation" EXACT [] synonym: "radium" RELATED [] is_a: FBcv:0000506 ! gamma ray [Term] id: FBcv:0000510 name: 32P namespace: origin_of_mutation def: "Mutation induced by exposure to 32P radiation." [FBC:MC] subset: camcur synonym: "32-Phosphorous" RELATED [] synonym: "mutation induced by 32-P irradiation" EXACT [] is_a: FBcv:0000504 ! ionizing radiation [Term] id: FBcv:0000511 name: 3H namespace: origin_of_mutation def: "Mutation induced by exposure to 3H radiation." [FBC:MC] subset: camcur synonym: "mutation induced by 3H irradiation" EXACT [] synonym: "tritium" RELATED [] is_a: FBcv:0000504 ! ionizing radiation [Term] id: FBcv:0000512 name: 3H-deoxycytidine namespace: origin_of_mutation def: "Mutation induced by exposure to 3H-deoxycytidine radiation." [FBC:MC] subset: camcur synonym: "mutation induced by 3H-deoxycytidine irradiation" EXACT [] is_a: FBcv:0000504 ! ionizing radiation [Term] id: FBcv:0000513 name: 3H-thymidine namespace: origin_of_mutation def: "Mutation induced by exposure to 3H-thymidine radiation." [FBC:MC] subset: camcur synonym: "mutation induced by 3H-thymidine irradiation" EXACT [] is_a: FBcv:0000504 ! ionizing radiation [Term] id: FBcv:0000514 name: Bevatron namespace: origin_of_mutation def: "Mutation induced by treatment in a Bevatron." [FBC:MC] subset: camcur synonym: "mutation induced by Bevatron irradiation" EXACT [] is_a: FBcv:0000504 ! ionizing radiation [Term] id: FBcv:0000515 name: deuteron namespace: origin_of_mutation def: "Mutation induced by exposure to deuteron radiation." [FBC:MC] subset: camcur synonym: "mutation induced by deuteron irradiation" EXACT [] is_a: FBcv:0000504 ! ionizing radiation [Term] id: FBcv:0000516 name: neutron namespace: origin_of_mutation def: "Mutation induced by exposure to neutron radiation." [FBC:MC] subset: camcur synonym: "mutation induced by neutron irradiation" EXACT [] is_a: FBcv:0000504 ! ionizing radiation [Term] id: FBcv:0000517 name: 252Cf fission neutron namespace: origin_of_mutation def: "Mutation induced by exposure to 252Cf fission neutron radiation." [FBC:MC] subset: camcur synonym: "mutation induced by 252Cf fission neutron irradiation" EXACT [] is_a: FBcv:0000516 ! neutron [Term] id: FBcv:0000518 name: X ray namespace: origin_of_mutation def: "Mutation induced by exposure to X rays." [FBC:MC] subset: camcur synonym: "mutation induced by X ray irradiation" EXACT [] is_a: FBcv:0000504 ! ionizing radiation [Term] id: FBcv:0000519 name: non-ionizing radiation namespace: origin_of_mutation def: "Mutation induced by exposure to non-ionizing radiation." [FBC:MC] subset: camcur synonym: "mutation induced by non-ionizing irradiation" EXACT [] is_a: FBcv:0000503 ! irradiation [Term] id: FBcv:0000520 name: magnetic field namespace: origin_of_mutation def: "Mutation induced by exposure to a magnetic field." [FBC:MC] subset: camcur synonym: "mutation induced by magnetic field irradiation" EXACT [] is_a: FBcv:0000519 ! non-ionizing radiation [Term] id: FBcv:0000521 name: radio waves namespace: origin_of_mutation def: "Mutation induced by exposure to radio waves." [FBC:MC] subset: camcur synonym: "mutation induced by radio waves irradiation" EXACT [] is_a: FBcv:0000519 ! non-ionizing radiation [Term] id: FBcv:0000522 name: stratosphere namespace: origin_of_mutation def: "Mutation induced by exposure to the stratosphere." [FBC:MC] subset: camcur synonym: "mutation induced by stratosphere irradiation" EXACT [] is_a: FBcv:0000519 ! non-ionizing radiation [Term] id: FBcv:0000523 name: supersonic namespace: origin_of_mutation def: "Mutation induced by exposure to supersonic radiation." [FBC:MC] subset: camcur synonym: "mutation induced by supersonic irradiation" EXACT [] is_a: FBcv:0000519 ! non-ionizing radiation [Term] id: FBcv:0000524 name: U.V. namespace: origin_of_mutation def: "Mutation induced by exposure to U.V. radiation." [FBC:MC] subset: camcur synonym: "mutation induced by U.V. irradiation" EXACT [] is_a: FBcv:0000519 ! non-ionizing radiation [Term] id: FBcv:0000525 name: chemical namespace: origin_of_mutation def: "Mutation induced by exposure to a chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances. (Definition imported and edited from 'chemical entity ; CHEBI:24431', which is related to this term.)." [CHEBI:24431, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by chemical exposure" EXACT [] is_a: FBcv:0000452 ! origin of mutation [Term] id: FBcv:0000526 name: alkylating agent namespace: origin_of_mutation def: "Any chemical (FBcv:0000525) that has role some alkylating agent (CHEBI:22333)." [CHEBI:22333, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by alkylating agent exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000527 name: diethyl sulfate namespace: origin_of_mutation def: "." [CHEBI:34699] subset: camcur synonym: "DES" RELATED [] synonym: "mutation induced by diethyl sulfate exposure" EXACT [] is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000528 name: 2-chloroethyl methanesulfonate namespace: origin_of_mutation def: "." [CHEBI:19508] subset: camcur synonym: "CB1506" RELATED [] synonym: "mutation induced by 2-chloroethyl methanesulfonate exposure" EXACT [] is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000529 name: 2-fluoroethyl methanesulfonate namespace: origin_of_mutation def: "." [CHEBI:19579] subset: camcur synonym: "CB1522" RELATED [] synonym: "mutation induced by 2-fluoroethyl methanesulfonate exposure" EXACT [] is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000530 name: ethyl methanesulfonate namespace: origin_of_mutation def: "." [CHEBI:23994] subset: camcur synonym: "CB1528" RELATED [] synonym: "EMS" RELATED [] synonym: "mutation induced by EMS exposure" EXACT [] synonym: "mutation induced by ethyl methanesulfonate exposure" EXACT [] is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000531 name: ethyl nitrosourea namespace: origin_of_mutation def: "Mutation induced by exposure to a urea compound having ethyl and nitroso substituents in the 1-position. (Definition imported and edited from 'N-ethyl-N-nitrosourea ; CHEBI:23995', which is related to this term.)." [CHEBI:23995, FBC:auto_generated_definition] subset: camcur synonym: "ENU" RELATED [] synonym: "mutation induced by ENU exposure" EXACT [] synonym: "mutation induced by ethyl nitrosourea exposure" EXACT [] synonym: "N-ethyl-N-nitrosourea" RELATED [CHEBI:23995] is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000532 name: hycanthon methanesulfonate namespace: origin_of_mutation def: "Mutation induced by exposure to a methanesulfonate salt resulting from the reaction of equimolar amounts of hycanthone and methanesulfonic acid. It was formerly used as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel. (Definition imported and edited from 'hycanthone mesylate ; CHEBI:24624', which is related to this term.)." [CHEBI:24624, FBC:auto_generated_definition] subset: camcur synonym: "HMS" RELATED [] synonym: "hycanthone mesylate" RELATED [CHEBI:24624] synonym: "mutation induced by HMS exposure" EXACT [] synonym: "mutation induced by hycanthon methanesulfonate exposure" EXACT [] is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000533 name: methyl methanesulfonate namespace: origin_of_mutation def: "Mutation induced by exposure to a methanesulfonate ester that has formula C2H6O3S. (Definition imported and edited from 'methyl methanesulfonate ; CHEBI:25255', which is related to this term.)." [CHEBI:25255, FBC:auto_generated_definition] subset: camcur synonym: "CB1540" RELATED [] synonym: "MMS" RELATED [] synonym: "mutation induced by methyl methanesulfonate exposure" EXACT [] synonym: "mutation induced by MMS exposure" EXACT [] is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000534 name: bis(2-chloroethyl) sulfide namespace: origin_of_mutation alt_id: FBcv:0000536 def: "Mutation induced by exposure to an ethyl sulfide that has formula C4H8Cl2S. (Definition imported and edited from 'bis(2-chloroethyl) sulfide ; CHEBI:25434', which is related to this term.)." [CHEBI:25434, FBC:auto_generated_definition] subset: camcur synonym: "1,1'-thiobis(2-chloroethane)" RELATED [CHEBI:25434] synonym: "CB1735" RELATED [] synonym: "mustard gas" RELATED [CHEBI:25434] synonym: "mutation induced by bis(2-chloroethyl) sulfide exposure" EXACT [] synonym: "mutation induced by mustard gas exposure" EXACT [] synonym: "mutation induced by sulfur gas exposure" EXACT [] synonym: "sulfur mustard" RELATED [CHEBI:25434] is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000535 name: N-methyl-N'-nitro-N-nitrosoguanidine namespace: origin_of_mutation def: "Mutation induced by exposure to an N-nitroguanidine compound having nitroso and methyl substituents at the N'-position (Definition imported and edited from 'N-methyl-N'-nitro-N-nitrosoguanidine ; CHEBI:21759', which is related to this term.)." [CHEBI:21759, FBC:auto_generated_definition] subset: camcur synonym: "MNNG" RELATED [] synonym: "mutation induced by N-methyl-N'-nitro-N-nitrosoguanidine exposure" EXACT [] synonym: "NNG" RELATED [] is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000537 name: minos ammunition for transposable element mutagenesis is_obsolete: true [Term] id: FBcv:0000538 name: carbamate namespace: origin_of_mutation def: "Mutation induced by exposure to an amino-acid anion that has formula CH2NO2. (Definition imported and edited from 'carbamate ; CHEBI:13941', which is related to this term.)." [CHEBI:13941, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by carbamate exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000539 name: urethane namespace: origin_of_mutation def: "Mutation induced by exposure to a carbamate ester that has formula C3H7NO2. (Definition imported and edited from 'urethane ; CHEBI:17967', which is related to this term.)." [CHEBI:17967, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by urethane exposure" EXACT [] is_a: FBcv:0000538 ! carbamate [Term] id: FBcv:0000540 name: vinyl carbamate namespace: origin_of_mutation def: "Mutation induced by exposure to a carbamate ester that has formula C3H5NO2. (Definition imported and edited from 'vinyl carbamate ; CHEBI:27292', which is related to this term.)." [CHEBI:27292, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by vinyl carbamate exposure" EXACT [] is_a: FBcv:0000538 ! carbamate [Term] id: FBcv:0000541 name: intercalating agent namespace: origin_of_mutation def: "Any chemical (FBcv:0000525) that has role some intercalator (CHEBI:24853)." [CHEBI:24853, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by intercalating agent exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000542 name: mitomycin C namespace: origin_of_mutation def: "Mutation induced by exposure to a mitomycin that has formula C15H18N4O5. (Definition imported and edited from 'mitomycin C ; CHEBI:27504', which is related to this term.)." [CHEBI:27504, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by mitomycin C exposure" EXACT [] is_a: FBcv:0000541 ! intercalating agent [Term] id: FBcv:0000543 name: quinacrine mustard namespace: origin_of_mutation def: "Mutation induced by exposure to an aminoacridine that has formula C23H28Cl3N3O. (Definition imported and edited from 'quinacrine mustard ; CHEBI:37595', which is related to this term.)." [CHEBI:37595, FBC:auto_generated_definition] comment: Mapped to CHEBI on basis of synonym - quinacrine mustard. Originaly primary name, ICR 100 is now relegated to a synonym subset: camcur synonym: "2-methoxy-6-[3-(ethyl-2-chloroethyl)aminopropylamino]acridine" RELATED [] synonym: "ICR 100" RELATED [CHEBI:37595] synonym: "mutation induced by quinacrine mustard exposure" EXACT [] is_a: FBcv:0000541 ! intercalating agent [Term] id: FBcv:0000544 name: ICR 170 namespace: origin_of_mutation def: "Mutation induced by exposure to an acridine that has formula C21H27Cl4N3O. (Definition imported and edited from 'ICR-170 ; CHEBI:21183', which is related to this term.)." [CHEBI:21183, FBC:auto_generated_definition] subset: camcur synonym: "2-methoxy-6-dichloro-9-(3-ethyl-2-chloroethyl-aminopropylamino)acridine-dihydrochloride" RELATED [] synonym: "mutation induced by ICR 170 exposure" EXACT [] is_a: FBcv:0000541 ! intercalating agent [Term] id: FBcv:0000545 name: 1,2-dibromoethane namespace: origin_of_mutation def: "Mutation induced by exposure to a bromoalkane that has formula C2H4Br2. (Definition imported and edited from '1,2-dibromoethane ; CHEBI:28534', which is related to this term.)." [CHEBI:28534, FBC:auto_generated_definition] subset: camcur synonym: "DBE" RELATED [] synonym: "mutation induced by 1,2-dibromoethane exposure" EXACT [] is_a: FBcv:0000541 ! intercalating agent [Term] id: FBcv:0000546 name: 1,2-dichloroethane namespace: origin_of_mutation def: "Mutation induced by exposure to a chloroethane that has formula C2H4Cl2. (Definition imported and edited from '1,2-dichloroethane ; CHEBI:27789', which is related to this term.)." [CHEBI:27789, FBC:auto_generated_definition] subset: camcur synonym: "DCE" RELATED [] synonym: "mutation induced by 1,2-dichloroethane exposure" EXACT [] is_a: FBcv:0000541 ! intercalating agent [Term] id: FBcv:0000547 name: 1-bromo-2-chloroethane namespace: origin_of_mutation def: "Mutation induced by exposure to a bromoalkane that has formula C2H4BrCl. (Definition imported and edited from '1-bromo-2-chloroethane ; CHEBI:19032', which is related to this term.)." [CHEBI:19032, FBC:auto_generated_definition] subset: camcur synonym: "BCE" RELATED [] synonym: "mutation induced by 1-bromo-2-chloroethane exposure" EXACT [] is_a: FBcv:0000541 ! intercalating agent [Term] id: FBcv:0000548 name: base analog namespace: origin_of_mutation def: "Mutation induced by exposure to a molecule that can substitute for a normal nucleobase in nucleic acids. (Definition imported and edited from 'nucleobase analogue ; CHEBI:67142', which is related to this term.)." [CHEBI:67142, FBC:auto_generated_definition] subset: camcur synonym: "nucleobase analogue" RELATED [CHEBI:67142] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000549 name: 5-bromouracil namespace: origin_of_mutation def: "Mutation induced by exposure to a pyrimidine having keto groups at the 2- and 4-positions and a bromo group at the 5-position. (Definition imported and edited from '5-bromouracil ; CHEBI:20552', which is related to this term.)." [CHEBI:20552, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by 5-bromouracil exposure" EXACT [] is_a: FBcv:0000548 ! base analog [Term] id: FBcv:0000550 name: 5-bromouridine namespace: origin_of_mutation def: "Mutation induced by exposure to a uridine having a bromo substituent at the 5-position. (Definition imported and edited from '5-bromouridine ; CHEBI:20553', which is related to this term.)." [CHEBI:20553, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by 5-bromouridine exposure" EXACT [] is_a: FBcv:0000548 ! base analog [Term] id: FBcv:0000551 name: enzyme inhibitor namespace: origin_of_mutation def: "Any chemical (FBcv:0000525) that has role some enzyme inhibitor (CHEBI:23924)." [CHEBI:23924, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by enzyme inhibitor exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000552 name: aminopterin namespace: origin_of_mutation def: "Mutation induced by exposure to a dicarboxylic acid that has formula C19H20N8O5. (Definition imported and edited from '4-aminofolic acid ; CHEBI:22526', which is related to this term.)." [CHEBI:22526, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by aminopterin exposure" EXACT [] is_a: FBcv:0000551 ! enzyme inhibitor [Term] id: FBcv:0000553 name: inorganic compound namespace: origin_of_mutation def: "Mutation induced by exposure to a molecular entity that contains no carbon. (Definition imported and edited from 'inorganic molecular entity ; CHEBI:24835', which is related to this term.)." [CHEBI:24835, FBC:auto_generated_definition] subset: camcur synonym: "inorganic molecular entity" EXACT [CHEBI:24835] synonym: "mutation induced by inorganic compound exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000554 name: cupric sulfate namespace: origin_of_mutation def: "Mutation induced by exposure to a metal sulfate compound having copper(2+) as the counterion. (Definition imported and edited from 'copper(2+) sulfate ; CHEBI:23414', which is related to this term.)." [CHEBI:23414, FBC:auto_generated_definition] subset: camcur synonym: "copper(2+) sulfate" RELATED [CHEBI:23414] synonym: "mutation induced by cupric sulfate" EXACT [] is_a: FBcv:0000553 ! inorganic compound [Term] id: FBcv:0000555 name: H3BO3 namespace: origin_of_mutation def: "Mutation induced by exposure to a member of the boric acids that has formula BH3O3. (Definition imported and edited from 'boric acid ; CHEBI:33118', which is related to this term.)." [CHEBI:33118, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by H3BO3 exposure" EXACT [] is_a: FBcv:0000553 ! inorganic compound [Term] id: FBcv:0000556 name: sodium bisulphite namespace: origin_of_mutation def: "Mutation induced by exposure to a sulfite salt that has formula HNaO3S. (Definition imported and edited from 'sodium hydrogensulfite ; CHEBI:26709', which is related to this term.)." [CHEBI:26709, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by sodium bisulphite exposure" EXACT [] is_a: FBcv:0000553 ! inorganic compound [Term] id: FBcv:0000557 name: sodium fluoride namespace: origin_of_mutation def: "Mutation induced by exposure to a metal fluoride salt with a Na(+) counterion. (Definition imported and edited from 'sodium fluoride ; CHEBI:28741', which is related to this term.)." [CHEBI:28741, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by sodium fluoride exposure" EXACT [] is_a: FBcv:0000553 ! inorganic compound [Term] id: FBcv:0000558 name: epoxy hydrocarbon namespace: origin_of_mutation subset: camcur synonym: "mutation induced by epoxy hydrocarbon exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000559 name: diepoxybutane namespace: origin_of_mutation def: "Mutation induced by exposure to an epoxide that has formula C4H6O2. (Definition imported and edited from 'diepoxybutane ; CHEBI:23704', which is related to this term.)." [CHEBI:23704, FBC:auto_generated_definition] subset: camcur synonym: "DEB" RELATED [] synonym: "erythritol anhydride" RELATED [] synonym: "mutation induced by diepoxybutane exposure" EXACT [] is_a: FBcv:0000558 ! epoxy hydrocarbon [Term] id: FBcv:0000560 name: diepoxyoctane namespace: origin_of_mutation def: "." [CHEBI:23705] subset: camcur synonym: "1,2:7,8-diepoxyoctane" RELATED [CHEBI:23705] synonym: "mutation induced by diepoxyoctane exposure" EXACT [] is_a: FBcv:0000558 ! epoxy hydrocarbon [Term] id: FBcv:0000561 name: unclassified chemical namespace: origin_of_mutation subset: camcur is_obsolete: true consider: FBcv:0000525 [Term] id: FBcv:0000562 name: 1,2:5,6-dibenzanthracene namespace: origin_of_mutation def: "Mutation induced by exposure to an ortho-fused polycyclic arene that has formula C22H14. (Definition imported and edited from 'dibenz[a,h]anthracene ; CHEBI:35299', which is related to this term.)." [CHEBI:35299, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by 1,2:5,6-dibenzanthracene exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000563 name: 1,4-dimethanesulfonoxy-1,4-dimethylbutane namespace: origin_of_mutation def: "Mutation induced by exposure to a methanesulfonate ester that is hexane-2,5-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. (Definition imported and edited from 'dimethylmyleran ; CHEBI:67107', which is related to this term.)." [CHEBI:67107, FBC:auto_generated_definition] subset: camcur synonym: "1,4-dimethanesulfonoxy-1:4-dimethylbutane" RELATED [] synonym: "CB2348" RELATED [] synonym: "dimethylmyleran" RELATED [CHEBI:67107] synonym: "mutation induced by 1,4-dimethanesulfonoxy-1,4-dimethylbutane exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000564 name: 1,4-dimethanesulfonoxybut-2-yne namespace: origin_of_mutation subset: camcur synonym: "CB2058" RELATED [] synonym: "mutation induced by 1,4-dimethanesulfonoxybut-2-yne exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000565 name: dominance relationship qualifier namespace: dominance_qualifier def: "Dominance relationships describe the dependence of the expression of a phenotypic attribute of an allele on the genotype at the locus in question. An allele might be recessive with respect to one phenotypic attribute, but dominant with respect to another." [FBC:rd] is_a: FBcv:0000005 ! qualifier [Term] id: FBcv:0000566 name: 1,6-dimethylsulfonoxy D-mannitol namespace: origin_of_mutation subset: camcur synonym: "CB2511" RELATED [] synonym: "mutation induced by 1,6-dimethylsulfonoxy D-mannitol exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000567 name: 1,6-dimethylsulfonoxy L-mannitol namespace: origin_of_mutation subset: camcur synonym: "CB2628" RELATED [] synonym: "mutation induced by 1,6-dimethylsulfonoxy L-mannitol exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000568 name: 1-amino-2-naphthol-4-sulfonic acid namespace: origin_of_mutation def: "Mutation induced by exposure to an aminonaphthalene that has formula C10H9NO4S. (Definition imported and edited from '4-amino-3-hydroxynaphthalene-1-sulfonic acid ; CHEBI:19024', which is related to this term.)." [CHEBI:19024, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by 1-amino-2-naphthol-4-sulfonic acid exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000569 name: lucanthone namespace: origin_of_mutation def: "Mutation induced by exposure to a thioxanthen-9-one compound having a methyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. Formerly used for the treatment of schistosomiasis. It is a prodrug, being metabolised to hycanthone. (Definition imported and edited from 'lucanthone ; CHEBI:51052', which is related to this term.)." [CHEBI:51052, FBC:auto_generated_definition] subset: camcur synonym: "1-diethylaminoethylethylamino-4-methyl-thioxanthenone" RELATED [] synonym: "1-{[2-(diethylamino)ethyl]amino}-4-methyl-9H-thioxanthen-9-one" RELATED [CHEBI:51052] synonym: "lucanthone" RELATED [CHEBI:51052] synonym: "mutation induced by lucanthone exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000570 name: 2-methoxyethanol namespace: origin_of_mutation def: "Mutation induced by exposure to a hydroxyether that has formula C3H8O2. (Definition imported and edited from '2-methoxyethanol ; CHEBI:46790', which is related to this term.)." [CHEBI:46790, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by 2-methoxyethanol exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000571 name: 2,5-bis(ethyleneimino)-1,4-benzoquinone namespace: origin_of_mutation def: "Mutation induced by exposure to a member of the class of benzoquinones that is 1,4-benzoquinone in which the hydrogens at positions 2 and 5 are replaced by aziridin-1-yl groups. (Definition imported and edited from '2,5-bis(aziridin-1-yl)-1,4-benzoquinone ; CHEBI:19363', which is related to this term.)." [CHEBI:19363, FBC:auto_generated_definition] subset: camcur synonym: "2,5,-bisethylene-imine-1,4-benzoquinone" RELATED [] synonym: "mutation induced by 2,5-bis(ethyleneimino)-1,4-benzoquinone exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000572 name: 7-bromomethyl-12-methylbenz[a]anthracene namespace: origin_of_mutation def: "Mutation induced by exposure to a member of the class of tetraphenes that is tetraphene in which the hydrogens at positions 7 and 12 are replaced by bromomethyl and methyl groups, respectively. (Definition imported and edited from '7-bromomethyl-12-methyltetraphene ; CHEBI:20787', which is related to this term.)." [CHEBI:20787, FBC:auto_generated_definition] subset: camcur synonym: "7-bromomethyl 12 methyl benz&agr; anthracine" RELATED [] synonym: "7-bromomethyl 12 methyl benzalpha anthracine" RELATED [] synonym: "7-bromomethyl-12-methyltetraphene" RELATED [CHEBI:20787] synonym: "mutation induced by 7-bromomethyl-12-methylbenz[a]anthracene exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000573 name: actinomycin D namespace: origin_of_mutation def: "Mutation induced by exposure to an actinomycin that has formula C62H86N12O16. (Definition imported and edited from 'actinomycin D ; CHEBI:27666', which is related to this term.)." [CHEBI:27666, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by actinomycin D exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000574 name: benzo(alpha)pyrene namespace: origin_of_mutation def: "Mutation induced by exposure to an ortho- and peri-fused polycyclic arene consisting of five fused benzene rings. (Definition imported and edited from 'benzo[a]pyrene ; CHEBI:29865', which is related to this term.)." [CHEBI:29865, FBC:auto_generated_definition] subset: camcur synonym: "benzo(&agr;)pyrene" RELATED [] synonym: "benzo[a]pyrene" RELATED [CHEBI:29865] synonym: "mutation induced by benzo(alpha)pyrene exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000575 name: caffeine namespace: origin_of_mutation def: "Mutation induced by exposure to a trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7. (Definition imported and edited from 'caffeine ; CHEBI:27732', which is related to this term.)." [CHEBI:27732, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by caffeine exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000576 name: cisplatin namespace: origin_of_mutation def: "Mutation induced by exposure to a platinum-containing anticancer drug that interacts with, and forms cross-links between, DNA and proteins. It is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. (Definition imported and edited from 'cisplatin ; CHEBI:27899', which is related to this term.)." [CHEBI:27899, FBC:auto_generated_definition] subset: camcur synonym: "cis-dichlorodiammineplatinum(II)" RELATED [] synonym: "mutation induced by cisplatin exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000577 name: colchicine namespace: origin_of_mutation def: "Mutation induced by exposure to a carbotricyclic compound comprising 5,6,7,9-tetrahydrobenzo[a]heptalene having four methoxy substituents at the 1-, 2-, 3- and 10-positions as well as an oxo group at the 9-position and an acetamido group at the 7-position. (Definition imported and edited from 'colchicine ; CHEBI:23359', which is related to this term.)." [CHEBI:23359, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by colchicine exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000578 name: dimethyl sulfoxide namespace: origin_of_mutation def: "Mutation induced by exposure to a 2-carbon sulfoxide in which the sulfur atom has two methyl substituents. (Definition imported and edited from 'dimethyl sulfoxide ; CHEBI:28262', which is related to this term.)." [CHEBI:28262, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by dimethyl sulfoxide exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000579 name: DNA namespace: origin_of_mutation def: "Mutation induced by exposure to high molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms. (Definition imported and edited from 'deoxyribonucleic acid ; CHEBI:16991', which is related to this term.)." [CHEBI:16991, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by DNA treatment" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000580 name: ethyl ether namespace: origin_of_mutation def: "Mutation induced by exposure to an ether that has formula C4H10O. (Definition imported and edited from 'diethyl ether ; CHEBI:35702', which is related to this term.)." [CHEBI:35702, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by ethyl ether exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000581 name: ethylenimine namespace: origin_of_mutation def: "Mutation induced by exposure to a member of the aziridines that has formula C2H5N. (Definition imported and edited from 'aziridine ; CHEBI:30969', which is related to this term.)." [CHEBI:30969, FBC:auto_generated_definition] subset: camcur synonym: "EI" RELATED [] synonym: "mutation induced by ethylenimine exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000582 name: ethylene oxide namespace: origin_of_mutation def: "." [CHEBI:27561] subset: camcur synonym: "ethylene oxide" RELATED [CHEBI:27561] synonym: "mutation induced by ethylene oxide exposure" EXACT [] synonym: "oxirane" RELATED [CHEBI:27561] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000583 name: fagaronine namespace: origin_of_mutation def: "Mutation induced by exposure to a benzophenanthridine alkaloid that has formula C21H20NO4. (Definition imported and edited from 'fagaronine ; CHEBI:28954', which is related to this term.)." [CHEBI:28954, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by fagaronine exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000584 name: formaldehyde namespace: origin_of_mutation def: "Mutation induced by exposure to the simplest aldehyde. (Definition imported and edited from 'formaldehyde ; CHEBI:16842', which is related to this term.)." [CHEBI:16842, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by formaldehyde exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000585 name: hesperidine namespace: origin_of_mutation def: "Mutation induced by exposure to a disaccharide derivative that consists of hesperetin substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. (Definition imported and edited from 'hesperidin ; CHEBI:28775', which is related to this term.)." [CHEBI:28775, FBC:auto_generated_definition] subset: camcur synonym: "hesperidin" RELATED [CHEBI:28775] synonym: "mutation induced by hesperidine exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000586 name: hexamethylmelamine namespace: origin_of_mutation def: "Mutation induced by exposure to a triamino-1,3,5-triazine that has formula C9H18N6. (Definition imported and edited from 'hexamethylmelamine ; CHEBI:24564', which is related to this term.)." [CHEBI:24564, FBC:auto_generated_definition] subset: camcur synonym: "altretamine" RELATED [] synonym: "HMM" RELATED [] synonym: "mutation induced by hexamethylmelamine exposure" EXACT [] synonym: "mutation induced by HMM exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000587 name: hexamethylphosphoramide namespace: origin_of_mutation def: "Mutation induced by exposure to a phosphoramide that has formula C6H18N3OP. (Definition imported and edited from 'hexamethylphosphoric triamide ; CHEBI:24565', which is related to this term.)." [CHEBI:24565, FBC:auto_generated_definition] subset: camcur synonym: "HMPA" RELATED [] synonym: "mutation induced by hexamethylphosphoramide exposure" EXACT [] synonym: "mutation induced by HMPA exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000588 name: iodine namespace: origin_of_mutation def: "Mutation induced by exposure to chemical element with atomic number 53. (Definition imported and edited from 'iodine atom ; CHEBI:24859', which is related to this term.)." [CHEBI:24859, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by iodine exposure" EXACT [] is_a: FBcv:0000553 ! inorganic compound [Term] id: FBcv:0000589 name: Janus green B namespace: origin_of_mutation def: "Mutation induced by exposure to an organic chloride salt that has formula C30H31ClN6. (Definition imported and edited from 'Janus Green B chloride ; CHEBI:21184', which is related to this term.)." [CHEBI:21184, FBC:auto_generated_definition] subset: camcur synonym: "Janus green B chloride" RELATED [CHEBI:21184] synonym: "mutation induced by Janus green B exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000590 name: methoxy diethylnitrosamine namespace: origin_of_mutation def: "." [CHEBI:25234] comment: Mapped to CHEBI:25234 (1-methoxy-N-nitrosodiethylamine) based on synonym of nitrosodiethylamine being diethylnitrosamine and CHEBI:25234 being classified as a mutagen. subset: camcur synonym: "1-methoxy-N-nitrosodiethylamine" RELATED [CHEBI:25234] synonym: "mutation induced by methoxy diethylnitrosamine exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000591 name: natural gas namespace: origin_of_mutation subset: camcur synonym: "mutation induced by natural gas exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000592 name: nitrosomethyl urea namespace: origin_of_mutation def: "Mutation induced by exposure to an urea that has formula C2H5N3O2. (Definition imported and edited from 'N-methyl-N-nitrosurea ; CHEBI:50102', which is related to this term.)." [CHEBI:50102, FBC:auto_generated_definition] subset: camcur synonym: "MNU" RELATED [] synonym: "mutation induced by MNU exposure" EXACT [] synonym: "mutation induced by nitrosomethyl urea exposure" EXACT [] synonym: "N-methyl-N-nitrosourea" RELATED [CHEBI:50102] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000593 name: N-nitrosodimethylamine namespace: origin_of_mutation def: "Mutation induced by exposure to a nitrosamine that has formula C2H6N2O. (Definition imported and edited from 'N-nitrosodimethylamine ; CHEBI:35807', which is related to this term.)." [CHEBI:35807, FBC:auto_generated_definition] subset: camcur synonym: "DMN" RELATED [] synonym: "mutation induced by DMN exposure" EXACT [] synonym: "mutation induced by N-nitrosodimethylamine exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000594 name: p-N,N-di(2-chloroethyl)aminophenylvaleric acid namespace: origin_of_mutation def: "." [CHEBI:25813] subset: camcur synonym: "CB1356" RELATED [] synonym: "mutation induced by p-N,N-di(2-chloroethyl)aminophenylvaleric acid exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000595 name: p-N,N-di-(2-chloroethyl)amino-D-phenylalanine namespace: origin_of_mutation def: "." [CHEBI:25814] subset: camcur synonym: "CB3026" RELATED [] synonym: "mutation induced by p-N,N-di-(2-chloroethyl)amino-D-phenylalanine exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000596 name: p-N,N-di-(2-chloroethyl)amino-DL-phenylalanine namespace: origin_of_mutation def: "Mutation induced by exposure to a phenylalanine derivative comprising L-phenylalanine having [bis(2-chloroethyl)amino group at the 4-position on the phenyl ring. (Definition imported and edited from 'melphalan ; CHEBI:28876', which is related to this term.)." [CHEBI:28876, FBC:auto_generated_definition] subset: camcur synonym: "CB3007" RELATED [] synonym: "melphalan" RELATED [CHEBI:28876] synonym: "mutation induced by melphalan exposure" EXACT [] synonym: "mutation induced by p-N,N-di-(2-chloroethyl)amino-DL-phenylalanine exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000597 name: p-N,N-di-(2-chloroethyl)amino-L-phenylalanine namespace: origin_of_mutation def: "." [CHEBI:25816] subset: camcur synonym: "CB3025" RELATED [] synonym: "mutation induced by p-N,N-di-(2-chloroethyl)amino-L-phenylalanine exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000598 name: dominant temperature-sensitive lethal balancer comment: Consider - FBsv:0001009. is_obsolete: true [Term] id: FBcv:0000599 name: p-N,N-di-(2-chloroethyl)aminophenylethylamine namespace: origin_of_mutation def: "Mutation induced by exposure to an organochlorine compound that has formula C12H18Cl2N2. (Definition imported and edited from '4-(2-aminoethyl)-N,N-bis(2-chloroethyl)aniline ; CHEBI:25818', which is related to this term.)." [CHEBI:25818, FBC:auto_generated_definition] subset: camcur synonym: "CB3034" RELATED [] synonym: "mutation induced by p-N,N-di-(2-chloroethyl)aminophenylethylamine exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000600 name: p-p'-N,N-di(2-chloroethyl)aminophenoxyphenylalanine namespace: origin_of_mutation def: "." [CHEBI:25829] subset: camcur synonym: "CB305" RELATED [] synonym: "mutation induced by p-p'-N,N-di(2-chloroethyl)aminophenoxyphenylalanine exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000601 name: quinhydrone namespace: origin_of_mutation def: "Mutation induced by exposure to an addition compound that has formula C12H10O4. (Definition imported and edited from 'quinhydrone ; CHEBI:26491', which is related to this term.)." [CHEBI:26491, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by quinhydrone exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000602 name: S-2-chloroethylcysteine namespace: origin_of_mutation def: "." [CHEBI:22025] subset: camcur synonym: "CB1592" RELATED [] synonym: "mutation induced by S-2-chloroethylcysteine exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000603 name: styryl quinoline namespace: origin_of_mutation def: "." [CHEBI:26800] subset: camcur synonym: "CB3086" RELATED [] synonym: "mutation induced by styryl quinoline exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000604 name: triaziquone namespace: origin_of_mutation def: "." [CHEBI:27090] subset: camcur synonym: "mutation induced by triaziquone exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000605 name: triethylenemelamine namespace: origin_of_mutation def: "Mutation induced by exposure to a 1,3,5-triazine that has formula C9H12N6. (Definition imported and edited from 'tretamine ; CHEBI:27919', which is related to this term.)." [CHEBI:27919, FBC:auto_generated_definition] subset: camcur synonym: "CB1246" RELATED [] synonym: "mutation induced by triethylenemelamine exposure" EXACT [] synonym: "TEM" RELATED [] synonym: "tretamine" RELATED [CHEBI:27919] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000606 name: allele assay method namespace: mode_of_assay is_a: FBcv:0000807 ! allele descriptor [Term] id: FBcv:0000607 name: In transgenic Drosophila namespace: mode_of_assay subset: camcur is_a: FBcv:0000606 ! allele assay method [Term] id: FBcv:0000608 name: Whole-organism transient assay namespace: mode_of_assay subset: camcur is_a: FBcv:0000606 ! allele assay method [Term] id: FBcv:0000609 name: Drosophila cell culture namespace: mode_of_assay subset: camcur xref: abbrev:3 is_a: FBcv:0000606 ! allele assay method [Term] id: FBcv:0000610 name: In transgenic Drosophila (allele of one drosophilid species in genome of another drosophilid) namespace: mode_of_assay subset: camcur xref: abbrev:5 is_a: FBcv:0000607 ! In transgenic Drosophila [Term] id: FBcv:0000611 name: Whole-organism transient assay (allele from one drosophilid species assayed in another drosophilid) namespace: mode_of_assay subset: camcur xref: abbrev:6 is_a: FBcv:0000608 ! Whole-organism transient assay [Term] id: FBcv:0000612 name: In transgenic Drosophila (allele of foreign species in genome of drosophilid) namespace: mode_of_assay subset: camcur xref: abbrev:7 is_a: FBcv:0000607 ! In transgenic Drosophila [Term] id: FBcv:0000613 name: Whole-organism transient assay (allele of foreign species assayed in drosophilid) namespace: mode_of_assay subset: camcur xref: abbrev:8 is_a: FBcv:0000608 ! Whole-organism transient assay [Term] id: FBcv:0000614 name: stock descriptor comment: Consider - FBsv:0000000. is_obsolete: true [Term] id: FBcv:0000615 name: extracted wild-type chromosome is_obsolete: true [Term] id: FBcv:0000616 name: laboratory stock comment: I don't think this is a useful term. is_obsolete: true [Term] id: FBcv:0000617 name: selected wild-type stock is_obsolete: true [Term] id: FBcv:0000618 name: wild-type stock comment: Consider - FBsv:0001005. is_obsolete: true [Term] id: FBcv:0000619 name: isogenic stock comment: Consider - FBsv:0001002. is_obsolete: true [Term] id: FBcv:0000620 name: genetic interaction qualifier namespace: genetic_interaction_type is_a: FBcv:0000005 ! qualifier [Term] id: FBcv:0000621 name: suppressor namespace: genetic_interaction_type def: "The genotype g1 is a suppressor of genotype g2 if (and only if) the phenotype due to g2 is made less severe by g1." [FBC:DOS, FlyBase:FBrf0000957, ISBN:978-0-387-52054-4] comment: Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA28b-q. Proforma field: GA29b-q. is_a: FBcv:0000620 ! genetic interaction qualifier [Term] id: FBcv:0000622 name: suppressible namespace: genetic_interaction_type def: "A phenotype due to genotype g1 is suppressible by genotype g2 if the if the phenotype due to the genotype g1g2 is less severe than that due to g1 alone." [FBC:DOS, FlyBase:FBrf0000957, ISBN:978-0-387-52054-4] comment: Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA28b-q. Proforma field: GA29b-q. subset: camcur is_a: FBcv:0000620 ! genetic interaction qualifier [Term] id: FBcv:0000623 name: enhancer namespace: genetic_interaction_type def: "Genotype g1 is enhancer of genotype g2 if (and only if) the phenotype due to the genotype g1g2 is more severe than the sum of phenotypes due to g1 and g2, where all comparisons are under identical environmental conditions." [FBC:DOS, FlyBase:FBrf0000957, ISBN:978-0-387-52054-4] comment: Not used directly in curation, but automatically inferred from its inverse (enhanceable). is_a: FBcv:0000620 ! genetic interaction qualifier [Term] id: FBcv:0000624 name: enhanceable namespace: genetic_interaction_type def: "A phenotype due to genotype g1 is enhanceable by genotype g2 if (and only if) the phenotype due to the genotype g1g2 is more severe than the sum of phenotypes due to g1 and g2, where all comparisons are under identical environmental conditions." [FBC:DOS, FlyBase:FBrf0000957, ISBN:978-0-387-52054-4] comment: Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA28b-q. Proforma field: GA29b-q. subset: camcur is_a: FBcv:0000620 ! genetic interaction qualifier [Term] id: FBcv:0000625 name: non-enhancer namespace: genetic_interaction_type comment: Not used directly in curation, but automatically inferred from its inverse (non-enhanceable). is_a: FBcv:0000620 ! genetic interaction qualifier [Term] id: FBcv:0000626 name: non-enhanceable namespace: genetic_interaction_type def: "A phenotype due to genotype g1 is non-enhanceable by genotype g2 if (and only if) the phenotype due to the genotype g1g2 is no more severe than the sum of phenotypes due to g1 and g2, where all comparisons are under identical environmental conditions." [FBC:DOS, FlyBase:FBrf0000957, ISBN:978-0-387-52054-4] comment: Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA28b-q. Proforma field: GA29b-q. subset: camcur is_a: FBcv:0000620 ! genetic interaction qualifier [Term] id: FBcv:0000627 name: non-suppressor namespace: genetic_interaction_type comment: Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA28b-q. Proforma field: GA29b-q. is_a: FBcv:0000620 ! genetic interaction qualifier [Term] id: FBcv:0000628 name: non-suppressible namespace: genetic_interaction_type def: "A phenotype due to genotype g1 is non-suppressible by genotype g2 if (and only if) the phenotype due to the genotype g1g2 is no less severe than the phenotype due to g1 alone." [FBC:DOS, FlyBase:FBrf0000957, ISBN:978-0-387-52054-4] comment: Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA28b-q. Proforma field: GA29b-q. subset: camcur is_a: FBcv:0000620 ! genetic interaction qualifier [Term] id: FBcv:0000629 name: dominant temperature-sensitive lethal balancer for chromosome 2 is_obsolete: true [Term] id: FBcv:0000630 name: dominant temperature-sensitive lethal balancer for chromosome 3 is_obsolete: true [Term] id: FBcv:0000631 name: DrosDel Project deficiency core kit stock is_obsolete: true [Term] id: FBcv:0000632 name: Bloomington Stock Center deficiency kit stock comment: Consider - FBsv:0000601. is_obsolete: true [Term] id: FBcv:0000633 name: Exelixis deficiency kit stock is_obsolete: true [Term] id: FBcv:0000634 name: duplication kit stock is_obsolete: true [Term] id: FBcv:0000635 name: Cambridge 2 duplication kit stock comment: Consider - FBsv:0000603. is_obsolete: true [Term] id: FBcv:0000636 name: Bloomington duplication kit stock comment: Consider - FBsv:0000602. is_obsolete: true [Term] id: FBcv:0000637 name: Gene Disruption Project stock is_obsolete: true [Term] id: FBcv:0000638 name: sequenced strain comment: Consider - FBsv:0001003. is_obsolete: true [Term] id: FBcv:0000639 name: Golic gene replacement kit stock comment: Consider - FBsv:0000604. is_obsolete: true [Term] id: FBcv:0000640 name: Golic laboratory gene replacement kit stock is_obsolete: true [Term] id: FBcv:0000641 name: stock by cytotype is_obsolete: true [Term] id: FBcv:0000642 name: H cytotype stock is_obsolete: true [Term] id: FBcv:0000643 name: hobo family transposable element insertions present is_obsolete: true [Term] id: FBcv:0000644 name: hobo family transposable element insertions absent is_obsolete: true [Term] id: FBcv:0000645 name: P cytotype stock is_obsolete: true [Term] id: FBcv:0000646 name: P-element family transposable element insertions absent is_obsolete: true [Term] id: FBcv:0000647 name: P-element family transposable element insertions present is_obsolete: true [Term] id: FBcv:0000648 name: mapping stock is_obsolete: true [Term] id: FBcv:0000649 name: visible allele recombination mapping stock is_obsolete: true [Term] id: FBcv:0000650 name: editorial namespace: pub_type def: "Work consisting of a statement of the opinions, beliefs, and policy of the editor or publisher of a journal, usually on current matters of medical or scientific significance to the medical community or society at large." [http://www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?view=expanded&field=uid&term=D016421] subset: camcur xref: MeSH:D016421 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000651 name: meeting report namespace: pub_type comment: This term was obsoleted to conform with the MeSH terms used by PubMed. Please use 'FBcv:0000199 subset: camcur is_obsolete: true replaced_by: FBcv:0000199 [Term] id: FBcv:0000652 name: compendium namespace: pub_type def: "A publication containing a collection of separate articles written by distinct authors." [FBC:SM] subset: camcur synonym: "multipub" EXACT [FBC:SM] synonym: "multipublication" EXACT [FBC:SM] synonym: "Parent publication" EXACT [FBC:SM] is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000653 name: subset namespace: expression_qualifier def: "Restricted to unknown subtype(s) of a specifed type." [FBC:DS] is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000654 name: embryonic pattern qualifier namespace: embryonic_pattern_qualifier is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000655 name: Vienna Drosophila RNAi Center comment: Consider - FBsv:0000107. synonym: "VDRC" EXACT [] synonym: "Vienna" EXACT [] is_obsolete: true [Term] id: FBcv:0000656 name: frozen specimen comment: Consider - FBsv:0000008. is_obsolete: true [Term] id: FBcv:0000657 name: mutant stock is_obsolete: true [Term] id: FBcv:0000658 name: DrosDel Project deficiency stock is_obsolete: true [Term] id: FBcv:0000659 name: deficiency stock is_obsolete: true [Term] id: FBcv:0000660 name: inbred line comment: Consider - FBsv:0000501. is_obsolete: true [Term] id: FBcv:0000661 name: isofemale line comment: Consider - FBsv:0000502. is_obsolete: true [Term] id: FBcv:0000662 name: recently collected stock def: "A stock established from flies collected in the wild within the past 3 years." [FBC:KM] comment: Consider - FBsv:0000504. is_obsolete: true [Term] id: FBcv:0000663 name: transposable element-containing stock is_obsolete: true [Term] id: FBcv:0000664 name: duplication stock is_obsolete: true [Term] id: FBcv:0000665 name: body size defective namespace: phenotypic_class def: "Phenotype that is an abnormality in body size compared to wild-type animals raised under the same conditions as the animals exhibiting the phenotype." [FBC:DOS] subset: camcur is_a: FBcv:0000354 ! visible is_a: FBcv:0000357 ! size defective [Term] id: FBcv:0000666 name: conference proceedings namespace: pub_type comment: This term was obsoleted to conform with the MeSH terms used by PubMed. Please use 'FBcv:0000199 is_obsolete: true replaced_by: FBcv:0000199 [Term] id: FBcv:0000667 name: website namespace: pub_type def: "A set of related web pages containing content such as text, images, video, audio, etc., prepared and maintained as a collection of information on a particular subject." [FBC:SM] is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000668 name: cell adhesion defective namespace: phenotypic_class def: "Phenotype that is a defect in cell adhesion (GO:0007155). 'cell adhesion' is defined as: 'The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.'" [FBC:DOS, GOC:hb, GOC:pf] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000669 name: hatching behavior defective namespace: phenotypic_class def: "Phenotype that is a defect in hatching behavior (GO:0035187). 'hatching behavior' is defined as: 'The specific behavior of an organism during the emergence from an egg shell. In Drosophila for example, the larva swings its head reiteratively through a semicircular arc, using its mouth hooks to tear apart the chorion in front of it and thus free itself from within the egg shell.'" [FBC:DOS, GOC:pr, PMID:10436051] subset: camcur synonym: "hatching behaviour defective" EXACT [] is_a: FBcv:0000387 ! behavior defective [Term] id: FBcv:0000670 name: eclosion defective namespace: phenotypic_class def: "Phenotype that is a defect in eclosion (GO:0007562). 'eclosion' is defined as: 'The emergence of an adult insect from a pupa case.'" [FBC:DOS, GOC:dgh, GOC:dos, GOC:mah, ISBN:0198600461] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000671 name: cell cycle defective namespace: phenotypic_class def: "Phenotype that is a defect in cell cycle (GO:0007049). 'cell cycle' is defined as: 'The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.'" [FBC:DOS, GOC:go_curators, GOC:mtg_cell_cycle] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000672 name: endomitotic cell cycle defective namespace: phenotypic_class def: "Phenotype that is a defect in endomitotic cell cycle (GO:0007113). 'endomitotic cell cycle' is defined as: 'A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell.'" [FBC:DOS, GOC:curators, GOC:dos, GOC:expert_vm] subset: camcur synonym: "endocycle defective" EXACT [] is_a: FBcv:0000432 ! mitotic cell cycle defective [Term] id: FBcv:0000673 name: sequenced whole genome stock comment: Consider - FBsv:0001003. is_obsolete: true [Term] id: FBcv:0000674 name: phiC31 based integration system is_obsolete: true [Term] id: FBcv:0000675 name: phiC31 docking site stock is_obsolete: true [Term] id: FBcv:0000676 name: multi-female collection comment: Consider - FBsv:0000503. is_obsolete: true [Term] id: FBcv:0000677 name: 60-70% egg length namespace: spatial_qualifier def: "60-70% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length created_by: djs93 creation_date: 2009-05-28T03:54:39Z [Term] id: FBcv:0000678 name: 80-100% egg length namespace: spatial_qualifier def: "80-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length created_by: djs93 creation_date: 2009-05-28T03:55:30Z [Term] id: FBcv:0000679 name: circadian behavior defective namespace: phenotypic_class def: "Phenotype that is a defect in circadian behavior (GO:0048512). 'circadian behavior' is defined as: 'The specific behavior of an organism that recurs with a regularity of approximately 24 hours.'" [FBC:DOS, GOC:bf, GOC:go_curators, GOC:pr] subset: camcur is_a: FBcv:0000387 ! behavior defective is_a: FBcv:0000394 ! circadian rhythm defective created_by: djs93 creation_date: 2009-11-30T11:06:35Z [Term] id: FBcv:0000680 name: proboscis extension reflex defective namespace: phenotypic_class def: "Phenotype that is a defect in proboscis extension reflex (GO:0007637). 'proboscis extension reflex' is defined as: 'The extension, through direct muscle actions, of the proboscis (the trunk-like extension of the mouthparts on the adult external head) in response to a sugar stimulus.'" [FB:FBrf0044924, FBC:DOS, GOC:jid] subset: camcur is_a: FBcv:0000403 ! chemosensitive behavior defective [Term] id: FBcv:0000681 name: sensory perception defective namespace: phenotypic_class def: "Phenotype that is a defect in sensory perception (GO:0007600). 'sensory perception' is defined as: 'The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.'" [FBC:DOS, GOC:ai, GOC:dph] subset: camcur is_a: FBcv:0001347 ! phenotype created_by: djs93 creation_date: 2010-02-23T12:28:26Z [Term] id: FBcv:0000682 name: touch perception defective namespace: phenotypic_class def: "Phenotype that is a defect in sensory perception of touch (GO:0050975). 'sensory perception of touch' is defined as: 'The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach).'" [FBC:DOS, GOC:ai] subset: camcur synonym: "touch perception defective" RELATED [] is_a: FBcv:0000681 ! sensory perception defective [Term] id: FBcv:0000683 name: temperature response defective namespace: phenotypic_class def: "Phenotype that is a defect in response to temperature stimulus (GO:0009266). 'response to temperature stimulus' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.'" [FBC:DOS, GOC:hb] subset: camcur is_a: FBcv:0001347 ! phenotype created_by: djs93 creation_date: 2010-02-23T12:51:02Z [Term] id: FBcv:0000684 name: cold stress response defective namespace: phenotypic_class def: "Phenotype that is a defect in response to cold (GO:0009409). 'response to cold' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.'" [FBC:DOS, GOC:lr] subset: camcur is_a: FBcv:0000408 ! stress response defective is_a: FBcv:0000683 ! temperature response defective created_by: djs93 creation_date: 2010-02-23T02:11:27Z [Term] id: FBcv:0000685 name: parental effect namespace: genotype_to_phenotype_relation def: "Parental effects describe the dependence of the expression of a phenotypic attribute of an allele on the parent from which that allele is inherited." [FBC:rd] is_a: FBcv:0000809 ! phenotype qualifier [Term] id: FBcv:0000686 name: axis specification defective namespace: phenotypic_class def: "Phenotype that is a defect in axis specification (GO:0009798). 'axis specification' is defined as: 'The establishment, maintenance and elaboration of a pattern along a line or around a point.'" [FBC:DOS, GOC:dph, GOC:go_curators, GOC:isa_complete] comment: This phenotypic class does not encompass planar polarity. subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000687 name: balancer descriptor is_a: FBcv:0000013 ! descriptor [Term] id: FBcv:0000688 name: amorphic allele namespace: allele_class def: "An allele that completely lacks function, coding either for a completely inactive gene product or none at all." [FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur synonym: "amorph" RELATED [] synonym: "null" RELATED [] is_a: FBcv:0000287 ! loss of function allele created_by: djs93 creation_date: 2010-09-06T03:57:21Z [Term] id: FBcv:0000689 name: amorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to completely lack function, producing either a completely inactive gene product or none at all." [FlyBase:FBrf0049147] subset: camcur synonym: "molecular null" EXACT [] is_a: FBcv:0000688 ! amorphic allele created_by: djs93 creation_date: 2010-09-06T03:57:49Z [Term] id: FBcv:0000690 name: hypomorphic allele namespace: allele_class def: "Allele that makes a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity." [FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur synonym: "hypomorph" EXACT [] is_a: FBcv:0000287 ! loss of function allele created_by: djs93 creation_date: 2010-09-06T03:58:15Z [Term] id: FBcv:0000691 name: hypomorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to make a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity." [FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000690 ! hypomorphic allele created_by: djs93 creation_date: 2010-09-06T03:59:31Z [Term] id: FBcv:0000692 name: neomorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to produce a gene product with a novel function or expression pattern compared to wild-type." [FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000697 ! neomorphic allele created_by: djs93 creation_date: 2010-09-06T04:01:04Z [Term] id: FBcv:0000693 name: hypermorphic allele - molecular evidence namespace: allele_class def: "Allele shown by molecular evidence to make either a functionally wild-type gene product at increased levels or a gene product with the same function as wild-type but with increased activity." [FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000696 ! hypermorphic allele created_by: djs93 creation_date: 2010-09-06T04:01:04Z [Term] id: FBcv:0000694 name: antimorphic allele - molecular evidence namespace: allele_class def: "An allele that has been shown by molecular evidence to make a gene product that is antagonistic to the function of the wild-type gene product." [FlyBase:FBrf0049147] subset: camcur synonym: "dominant negative" RELATED [] is_a: FBcv:0000695 ! antimorphic allele created_by: djs93 creation_date: 2010-09-06T04:01:04Z [Term] id: FBcv:0000695 name: antimorphic allele namespace: allele_class def: "An allele that makes a gene product that is antagonistic to the function of the wild-type gene product." [FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur synonym: "antimorph" RELATED [] is_a: FBcv:0000290 ! gain of function allele created_by: djs93 creation_date: 2010-09-06T04:02:05Z [Term] id: FBcv:0000696 name: hypermorphic allele namespace: allele_class def: "An allele that makes either increased amounts of a normal gene product or a gene product with normal function but increased activity compared to wild-type." [FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur synonym: "hypermorph" RELATED [] is_a: FBcv:0000290 ! gain of function allele created_by: djs93 creation_date: 2010-09-06T04:02:45Z [Term] id: FBcv:0000697 name: neomorphic allele namespace: allele_class def: "An allele that makes a gene product with a novel function or expression pattern compared to wild-type." [FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur synonym: "neomorph" RELATED [] is_a: FBcv:0000290 ! gain of function allele created_by: djs93 creation_date: 2010-09-06T04:03:33Z [Term] id: FBcv:0000698 name: embryonic/larval segmentation phenotype namespace: phenotypic_class def: "A phenotype that is a disruption in the wild-type pattern of segments or parasegments of the embryo or larva." [FlyBase:FBrf0035438] comment: Commonly assayed on the basis of phenotypic effects on segmentally repeated cuticular patterns. subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000699 name: pair rule phenotype namespace: phenotypic_class def: "Embryonic/larval segmentation phenotype that is the complete or partial loss of alternate segments or parasegments." [FlyBase:FBrf0035438] comment: Commonly assayed on the basis of phenotypic effects on segmentally repeated cuticular patterns. subset: camcur is_a: FBcv:0000698 ! embryonic/larval segmentation phenotype [Term] id: FBcv:0000700 name: even pair-rule phenotype namespace: phenotypic_class def: "Embryonic/larval segmentation phenotype that is the complete or partial loss of even segments." [FlyBase:FBrf0035438] comment: Commonly assayed on the basis of phenotypic effects on segmentally repeated cuticular patterns. subset: camcur is_a: FBcv:0000699 ! pair rule phenotype [Term] id: FBcv:0000701 name: odd pair-rule phenotype namespace: phenotypic_class def: "Embryonic/larval segmentation phenotype that is the complete or partial loss of odd segments." [FlyBase:FBrf0035438] comment: Commonly assayed on the basis of phenotypic effects on segmentally repeated cuticular patterns. subset: camcur is_a: FBcv:0000699 ! pair rule phenotype [Term] id: FBcv:0000702 name: segment polarity phenotype namespace: phenotypic_class def: "Embryonic/larval segmentation phenotype in which some fraction of each segment (along the anterior-posterior axis) is deleted and replaced by a mirror image duplication of the remaining part of the segment." [FlyBase:FBrf0035438] comment: Commonly assayed on the basis of phenotypic effects on segmentally repeated cuticular patterns. subset: camcur is_a: FBcv:0000698 ! embryonic/larval segmentation phenotype [Term] id: FBcv:0000703 name: gap phenotype namespace: phenotypic_class def: "Embryonic/larval segmentation phenotype that is the complete loss of a contiguous stretch of 2 or more segments." [FlyBase:FBrf0035438] comment: Commonly assayed on the basis of phenotypic effects on segmentally repeated cuticular patterns. subset: camcur is_a: FBcv:0000698 ! embryonic/larval segmentation phenotype [Term] id: FBcv:0000704 name: chemical conditional namespace: environmental_qualifier def: "Phenotype expressed only in the presence or absence of some specific chemical whose presence or absence does not induce the same defect in wild-type animals." [FBC:DOS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000309 ! conditional created_by: djs93 creation_date: 2010-09-20T11:13:19Z [Term] id: FBcv:0000705 name: sleep defective namespace: phenotypic_class def: "Phenotype that is a defect in sleep (GO:0030431). 'sleep' is defined as: 'Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.'" [FBC:DOS, ISBN:0192800981] subset: camcur is_a: FBcv:0001347 ! phenotype created_by: djs93 creation_date: 2010-09-20T12:06:13Z [Term] id: FBcv:0000706 name: diapause defective namespace: phenotypic_class def: "Phenotype that is a defect in entry into diapause (GO:0055115). 'entry into diapause' is defined as: 'The dormancy process that results in entry into diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation.'" [FBC:DOS, GOC:ds, GOC:jid, GOC:mah] subset: camcur is_a: FBcv:0001347 ! phenotype created_by: djs93 creation_date: 2010-09-20T12:06:28Z [Term] id: FBcv:0000707 name: reproductive diapause defective namespace: phenotypic_class def: "Phenotype that is a defect in entry into reproductive diapause (GO:0055116). 'entry into reproductive diapause' is defined as: 'The dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.'" [FBC:DOS, GOC:ds, GOC:jid, GOC:mah] subset: camcur is_a: FBcv:0000706 ! diapause defective created_by: djs93 creation_date: 2010-09-20T12:21:29Z [Term] id: FBcv:0000708 name: starvation stress response defective namespace: phenotypic_class def: "Phenotype that is a defect in response to starvation (GO:0042594). 'response to starvation' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.'" [FBC:DOS, GOC:go_curators] subset: camcur is_a: FBcv:0000408 ! stress response defective [Term] id: FBcv:0000709 name: cell number defective namespace: phenotypic_class def: "Phenotype that is an increase or decrease in the number of cells in a whole animal or in some specific organ, tissue or clone of cells compared to wild-type. This phenotype is not necessarily accompanied by defects in cell growth - there may be a greater or lesser number of cells in an otherwise normal volume of tissue." [FBC:DOS] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000710 name: gene targeting by homologous recombination namespace: origin_of_mutation def: "Change of a genomic sequence via homologous recombinational repair (GO:0000724) that is induced by a double stranded break in an engineered donor construct that contains sequence homologous to the target gene." [FBC:MC, FlyBase:FBrf0202435] comment: Strictly, homologous recombinational repair (GO:0000724) defines only the endogenous process, not its use for engineered gene targeting. subset: camcur synonym: "change induced by gene targeting via homologous recombination" EXACT [] is_a: FBcv:0000470 ! recombination [Term] id: FBcv:0000711 name: ends-out gene targeting namespace: origin_of_mutation def: "Change of a genomic sequence via homologous recombinational repair (GO:0000724) that is induced by a double strand break on both sides of the homologous region in an engineered donor sequence. This double-strand break is usually generated by cutting at a single site adjacent to the homologous region in a circularized donor sequence. This typically generates a simple targeted replacement of the target sequence by the donor sequence. However, more complicated outcomes are possible." [FBC:MC, FlyBase:FBrf0167363, FlyBase:FBrf0202435] subset: camcur synonym: "change induced by ends-out gene targeting" EXACT [] is_a: FBcv:0000710 ! gene targeting by homologous recombination [Term] id: FBcv:0000712 name: ends-in gene targeting namespace: origin_of_mutation def: "Change of a genomic sequence via homologous recombinational repair (GO:0000724) that is induced by a double strand break within an engineered homologous donor sequence. This typically generates a tandem duplication of the homologous sequence from the donor, separated by the remainder of the incoming donor DNA. However, more complicated outcomes are possible." [FBC:MC, FlyBase:FBrf0167363, FlyBase:FBrf0202435] subset: camcur synonym: "change induced by ends-in gene targeting" EXACT [] is_a: FBcv:0000710 ! gene targeting by homologous recombination [Term] id: FBcv:0000713 name: jumpless namespace: phenotypic_class def: "Phenotype that is a inability to jump. This may be due to neurological or muscular defects." [FBC:DOS] subset: camcur is_a: FBcv:0000415 ! jumping defective created_by: djs93 creation_date: 2011-03-10T04:57:06Z [Term] id: FBcv:0000714 name: nutrition conditional namespace: environmental_qualifier def: "Phenotype only expressed under some specific nutritional regime." [FBC:DOS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000309 ! conditional created_by: djs93 creation_date: 2011-01-14T12:34:01Z [Term] id: FBcv:0000715 name: calorie restriction conditional namespace: environmental_qualifier def: "Phenotype only expressed under conditions where calorie intake is restricted." [FBC:DOS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000714 ! nutrition conditional created_by: djs93 creation_date: 2011-01-14T05:12:37Z [Term] id: FBcv:0000716 name: cell migration defective namespace: phenotypic_class def: "Phenotype that is a defect in cell migration (GO:0016477). 'cell migration' is defined as: 'The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.'" [FBC:DOS, GOC:cjm, GOC:dph, GOC:ems, GOC:pf, http://en.wikipedia.org/wiki/Cell_migration] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000717 name: increased cell growth namespace: phenotypic_class def: "Phenotype that is an increase in the rate of cell growth (GO:0016049) in a whole animal or in some specific organ tissue or clone of cells compared to wild-type." [FBC:DOS] subset: camcur is_a: FBcv:0000427 ! cell growth defective [Term] id: FBcv:0000718 name: decreased cell growth namespace: phenotypic_class def: "Phenotype that is an decrease in the rate of cell growth (GO:0016049) in a whole animal or in some specific organ tissue or clone of cells compared to wild-type." [FBC:DOS] subset: camcur is_a: FBcv:0000427 ! cell growth defective [Term] id: FBcv:0000719 name: atrophy namespace: phenotypic_class def: "Phenotype that is a decrease in size of an initially normally sized organ or tissue due to wasting away of cells." [FBC:DOS] subset: camcur is_a: FBcv:0000357 ! size defective created_by: djs93 creation_date: 2011-03-10T05:59:04Z [Term] id: FBcv:0000720 name: jump response defective namespace: phenotypic_class def: "Phenotype that is a defect or in or absence of a jump response (GO:0007630). The jump response in Drosophila is a reflex escape response that can be triggered by a number of signals including odor and light. Standard assays are commonly used to test odor and light induced jump response." [FlyBase:FBrf0187887, FlyBase:FBrf0191819] subset: camcur is_a: FBcv:0000414 ! locomotor behavior defective is_a: FBcv:0000415 ! jumping defective created_by: djs93 creation_date: 2011-03-11T08:03:28Z [Term] id: FBcv:0000721 name: mating behavior defective namespace: phenotypic_class def: "Phenotype that is a defect in mating behavior (GO:0007617). 'mating behavior' is defined as: 'The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes.'" [FBC:DOS, GOC:ai, GOC:dph] subset: camcur is_a: FBcv:0000387 ! behavior defective is_a: FBcv:0000400 ! mating defective [Term] id: FBcv:0000722 name: somatic clone - Minute background namespace: clone_qualifier def: "A clone of somatic cells that share a mutant genotype that includes being Minute +/+ and that is part of and derived from an animal with a different genotype that includes being Minute +/-." [FBC:DOS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000336 ! somatic clone created_by: djs93 creation_date: 2011-01-27T04:55:28Z [Term] id: FBcv:0000723 name: neoplasia namespace: phenotypic_class def: "Phenotype that consists of abnormal growth of a tissue or organ due to increased numbers of cells, but in which the affected tissue or organ does not maintain its normal form." [FBC:DOS] subset: camcur is_a: FBcv:0000357 ! size defective is_a: FBcv:0000362 ! increased cell number [Term] id: FBcv:0000724 name: hypoplasia namespace: phenotypic_class def: "Phenotype that is a reduction in size of an organ or tissue compared to wild-type due to reduced numbers of cells being produced during its development or growth." [FBC:DOS] comment: This term should not be used where an organ or tissue is reduced in size due to the wasting away of existing cells. subset: camcur is_a: FBcv:0000357 ! size defective is_a: FBcv:0000359 ! decreased cell number [Term] id: FBcv:0000725 name: oxidative stress response defective namespace: phenotypic_class def: "Phenotype that is a defect in response to oxidative stress (GO:0006979). 'response to oxidative stress' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.'" [FBC:DOS, GOC:jl, PMID:12115731] subset: camcur is_a: FBcv:0000408 ! stress response defective [Term] id: FBcv:0000726 name: virgin female namespace: sex_qualifier def: "Expressed in virgin females." [FBC:DOS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. May be used as a qualifier for gene or transgene expression or phenotype. Note - its use does not imply expression (of gene or phenotype) exclusively in virgin females. is_a: FBcv:0000334 ! female created_by: djs93 creation_date: 2011-04-21T01:10:32Z [Term] id: FBcv:0000727 name: mated female namespace: sex_qualifier def: "Expressed in mated females." [FBC:DOS] comment: May be used as a qualifier for gene or transgene expression or phenotype. Note - its use does not imply expression (of gene or phenotype) exclusively in mated females. is_a: FBcv:0000334 ! female created_by: djs93 creation_date: 2011-04-21T01:10:49Z [Term] id: FBcv:0000728 name: virgin male namespace: sex_qualifier def: "Expressed in virgin males." [FBC:DOS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. May be used as a qualifier for gene or transgene expression or phenotype. Note - its use does not imply expression (of gene or phenotype) exclusively in virgin males. is_a: FBcv:0000333 ! male created_by: djs93 creation_date: 2011-04-21T01:11:13Z [Term] id: FBcv:0000729 name: mated male namespace: sex_qualifier def: "Expressed in mated males." [FBC:DOS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. May be used as a qualifier for gene or transgene expression or phenotype. Note - its use does not imply expression (of gene or phenotype) exclusively in mated females. is_a: FBcv:0000333 ! male created_by: djs93 creation_date: 2011-04-21T01:11:21Z [Term] id: FBcv:0000730 name: virgin female limited namespace: sex_qualifier def: "Expression is limited to virgin females." [FBC:DOS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. May be used to qualify expression of phenotypes or of genes, transgenes etc. subset: camcur is_a: FBcv:0000308 ! female limited created_by: djs93 creation_date: 2011-04-21T01:11:46Z [Term] id: FBcv:0000731 name: mated female limited namespace: sex_qualifier def: "Expression is limited to mated females." [FBC:DOS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. May be used to qualify expression of phenotypes or of genes, transgenes etc. subset: camcur is_a: FBcv:0000308 ! female limited created_by: djs93 creation_date: 2011-04-21T01:11:59Z [Term] id: FBcv:0000732 name: mated male limited namespace: sex_qualifier def: "Expression is limited to mated males." [FBC:DOS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. May be used to qualify expression of phenotypes or of genes, transgenes etc. subset: camcur is_a: FBcv:0000307 ! male limited created_by: djs93 creation_date: 2011-04-21T01:12:14Z [Term] id: FBcv:0000733 name: virgin male limited namespace: sex_qualifier def: "Expression is limited to virgin males." [FBC:DOS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. May be used to qualify expression of phenotypes or of genes, transgenes etc. subset: camcur is_a: FBcv:0000307 ! male limited created_by: djs93 creation_date: 2011-04-21T01:13:00Z [Term] id: FBcv:0000734 name: terminal phenotype namespace: phenotypic_class def: "Embryonic/larval segmentation phenotype that is the complete or partial loss of terminal regions of the embryo/larva: the acron, telson and immediately adjacent segments." [FBC:DOS] subset: camcur is_a: FBcv:0000698 ! embryonic/larval segmentation phenotype created_by: djs93 creation_date: 2011-09-13T02:31:53Z [Term] id: FBcv:0000735 name: N-nitrosodiethylamine namespace: origin_of_mutation def: "Mutation induced by exposure to a nitrosamine that has formula C4H10N2O. (Definition imported and edited from 'N-nitrosodiethylamine ; CHEBI:34873', which is related to this term.)." [CHEBI:34873, FBC:auto_generated_definition] subset: camcur synonym: "mutation induced by N-nitrosodiethylamine exposure" EXACT [] synonym: "NDEA" RELATED [FlyBase:FBrf0139766] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000736 name: heat sensitive amorphic allele namespace: allele_class def: "An allele that completely lacks function (i.e. whose gene productive is completely inactive) at high temperatures, but that retains at least some function at lower temperatures." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000739 ! temperature conditional amorphic allele is_a: FBcv:0000746 ! heat sensitive loss of function allele relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:54:34Z [Term] id: FBcv:0000737 name: temperature conditional amorphic allele - genetic evidence namespace: allele_class def: "An allele inferred to completely lack function at some temperatures (restrictive temperatures) but not others (permissive temperatures) from the observation that addition of extra copies in the genome has no effect on the phenotype at the restrictive temperatures. Most commonly, evidence takes the form of the observation that the phenotype of homozygotes (2 copies) is identical to that seen when the allele is in trans to a deletion of the gene (1 copy)." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000288 ! amorphic allele - genetic evidence is_a: FBcv:0000739 ! temperature conditional amorphic allele relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:55:17Z [Term] id: FBcv:0000738 name: edited book namespace: pub_type def: "A publication that is not issued on a regular, ongoing basis containing separate articles or chapters (typically reviews) written by different authors on a single subject or related subjects, overseen by one or more editors." [FBC:SM] is_a: FBcv:0000652 ! compendium created_by: djs93 creation_date: 2012-07-10T04:05:08Z [Term] id: FBcv:0000739 name: temperature conditional amorphic allele namespace: allele_class def: "An allele that completely lacks function (i.e. whose gene productive is completely inactive) at some temperatures, but not others." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000688 ! amorphic allele is_a: FBcv:0000745 ! temperature conditional loss of function allele relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:57:02Z [Term] id: FBcv:0000740 name: cold sensitive amorphic allele - genetic evidence namespace: allele_class def: "An allele inferred to completely lack function at low temperatures (restrictive temperatures) but not at high temperatures (permissive temperatures) from the observation that adding extra copies in the genome has no effect on the phenotype at the restrictive temperatures. Most commonly, evidence takes the form of the observation that the phenotype of homozygotes (2 copies) is identical to that seen when the allele is in trans to a deletion of the gene (1 copy)." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000737 ! temperature conditional amorphic allele - genetic evidence is_a: FBcv:0001003 ! cold sensitive amorphic allele relationship: conditionality FBcv:0000312 ! cold sensitive created_by: djs93 creation_date: 2012-03-22T03:58:31Z [Term] id: FBcv:0000741 name: heat sensitive amorphic allele - genetic evidence namespace: allele_class def: "An allele inferred to completely lack function at high temperatures (restrictive temperatures) but not at low temperatures (permissive temperatures) from the observation that adding extra copies in the genome has no effect on the phenotype at the restrictive temperatures. Most commonly, evidence takes the form of the observation that the phenotype of homozygotes (2 copies) is identical to that seen when the allele is in trans to a deletion of the gene (1 copy)." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000736 ! heat sensitive amorphic allele is_a: FBcv:0000737 ! temperature conditional amorphic allele - genetic evidence relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:59:43Z [Term] id: FBcv:0000742 name: cold sensitive amorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to completely lack function at low temperatures (restrictive temperatures) but not at high temperatures (permissive temperatures)." [FBC:DOS, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000744 ! temperature conditional amorphic allele - molecular evidence is_a: FBcv:0001003 ! cold sensitive amorphic allele relationship: conditionality FBcv:0000312 ! cold sensitive created_by: djs93 creation_date: 2012-03-22T03:58:31Z [Term] id: FBcv:0000743 name: heat sensitive amorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to completely lack function at high temperatures (restrictive temperatures) but not at low temperatures (permissive temperatures)." [FBC:DOS, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000736 ! heat sensitive amorphic allele is_a: FBcv:0000744 ! temperature conditional amorphic allele - molecular evidence relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:59:43Z [Term] id: FBcv:0000744 name: temperature conditional amorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to completely lack function at some temperatures (restrictive temperatures) but not at others (permissive temperatures)." [FBC:DOS, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000689 ! amorphic allele - molecular evidence is_a: FBcv:0000739 ! temperature conditional amorphic allele relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:55:17Z [Term] id: FBcv:0000745 name: temperature conditional loss of function allele namespace: allele_class def: "An allele that at some temperatures but not others either makes no functional gene product or makes reduced levels of a normally functioning gene product or makes a gene product with reduced activity compared to wild-type." [FBC:DOS, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000287 ! loss of function allele relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:57:02Z [Term] id: FBcv:0000746 name: heat sensitive loss of function allele namespace: allele_class def: "An allele that at high temperatures but not low temperatures, either makes no functional gene product, makes reduced levels of a normally functioning gene product or makes a gene product with reduced activity compared to wild-type." [FBC:DOS, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000745 ! temperature conditional loss of function allele relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:54:34Z [Term] id: FBcv:0000747 name: cold sensitive loss of function allele namespace: allele_class def: "An allele that at low temperatures but not high temperatures, either makes no functional gene product, makes reduced levels of a normally functioning gene product or makes a gene product with reduced activity compared to wild-type." [FBC:DOS, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000745 ! temperature conditional loss of function allele relationship: conditionality FBcv:0000312 ! cold sensitive [Term] id: FBcv:0000748 name: temperature conditional gain of function allele namespace: allele_class def: "An allele that at some temperatures but not others, either makes a normally functioning gene product but at higher levels or in a different spatial or temporal pattern to wild-type, or a product with increased or novel activity compared to wild-type." [FBC:DOS, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000290 ! gain of function allele relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:57:02Z [Term] id: FBcv:0000749 name: heat sensitive gain of function allele namespace: allele_class def: "An allele that at high temperatures but not low temperatures, either makes a normally functioning gene product but at higher levels or in a different spatial or temporal pattern to wild-type, or a product with increased or novel activity compared to wild-type." [FBC:DOS, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000748 ! temperature conditional gain of function allele relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:54:34Z [Term] id: FBcv:0000750 name: cold sensitive gain of function allele namespace: allele_class def: "An allele that at low temperatures but not high temperatures, either makes a normally functioning gene product but at higher levels or in a different spatial or temporal pattern to wild-type, or a product with increased or novel activity compared to wild-type." [FBC:DOS, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000748 ! temperature conditional gain of function allele relationship: conditionality FBcv:0000312 ! cold sensitive [Term] id: FBcv:0000751 name: temperature conditional hypomorphic allele namespace: allele_class def: "An allele that, at some temperatures but not others, makes a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000690 ! hypomorphic allele is_a: FBcv:0000745 ! temperature conditional loss of function allele relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:57:02Z [Term] id: FBcv:0000752 name: heat sensitive hypomorphic allele namespace: allele_class def: "An allele that makes a gene product that is functionally equivalent to wild-type but which at high temperatures is present in a lesser amount or with lowered activity, and that retains normal levels of expression or activity at low temperatures." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000746 ! heat sensitive loss of function allele is_a: FBcv:0000751 ! temperature conditional hypomorphic allele relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:54:34Z [Term] id: FBcv:0000753 name: cold sensitive hypomorphic allele namespace: allele_class def: "An allele that makes a gene product that is functionally equivalent to wild-type but which at low temperatures is present in a lesser amount or with lowered activity, and that retains normal function at higher temperatures." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000747 ! cold sensitive loss of function allele is_a: FBcv:0000751 ! temperature conditional hypomorphic allele relationship: conditionality FBcv:0000312 ! cold sensitive [Term] id: FBcv:0000754 name: temperature conditional hypomorphic allele - genetic evidence namespace: allele_class def: "An allele inferred from genetic evidence to have normal activity at some temperatures (permissive temperatures) but at other temperatures to make a gene product with normal function but in a lesser amount or with lowered activity (non-permissive temperatures). The genetic evidence must consist of an observation extra copies in the genome decrease the expressivity and/or penetrance of the phenotype at non-permissive temperatures. Most commonly this evidence takes the form of experiments showing that the homozygote (2 copies) has a weaker phenotype at non-permissive temperatures than the allele in trans to a deletion of the gene (1 copy))." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000289 ! hypomorphic allele - genetic evidence is_a: FBcv:0000751 ! temperature conditional hypomorphic allele relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:55:17Z [Term] id: FBcv:0000755 name: cold sensitive hypomorphic allele - genetic evidence namespace: allele_class def: "An allele inferred from genetic evidence to have normal activity at high temperatures (permissive temperatures) but to make a gene product with normal function but in a lesser amount or with lowered activity at lower temperatures (non-permissive temperatures). The genetic evidence must consist of an observation extra copies in the genome decrease the expressivity and/or penetrance of the phenotype at non-permissive temperatures. Most commonly this evidence takes the form of experiments showing that the homozygote (2 copies) has a weaker phenotype at non-permissive temperatures than the allele in trans to a deletion of the gene (1 copy))." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000753 ! cold sensitive hypomorphic allele is_a: FBcv:0000754 ! temperature conditional hypomorphic allele - genetic evidence relationship: conditionality FBcv:0000312 ! cold sensitive created_by: djs93 creation_date: 2012-03-22T03:58:31Z [Term] id: FBcv:0000756 name: heat sensitive hypomorphic allele - genetic evidence namespace: allele_class def: "An allele inferred from genetic evidence to have normal activity at low temperatures (permissive temperatures) but to make a gene product with normal function but in a lesser amount or with lowered activity at higher temperatures (non-permissive temperatures). The genetic evidence must consist of an observation extra copies in the genome decrease the expressivity and/or penetrance of the phenotype at non-permissive temperatures. Most commonly this evidence takes the form of experiments showing that the homozygote (2 copies) has a weaker phenotype at non-permissive temperatures than the allele in trans to a deletion of the gene (1 copy))." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000752 ! heat sensitive hypomorphic allele is_a: FBcv:0000754 ! temperature conditional hypomorphic allele - genetic evidence relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:59:43Z [Term] id: FBcv:0000757 name: temperature conditional hypomorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to make a normal gene product in normal amounts at some temperatures, but at other temperatures to make a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity." [FBC:DOS, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000691 ! hypomorphic allele - molecular evidence is_a: FBcv:0000751 ! temperature conditional hypomorphic allele relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:55:17Z [Term] id: FBcv:0000758 name: cold sensitive hypomorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to make a normal gene product in normal amounts at high temperatures, but at lower temperatures to make a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity." [FBC:DOS, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000753 ! cold sensitive hypomorphic allele is_a: FBcv:0000757 ! temperature conditional hypomorphic allele - molecular evidence relationship: conditionality FBcv:0000312 ! cold sensitive created_by: djs93 creation_date: 2012-03-22T03:58:31Z [Term] id: FBcv:0000759 name: heat sensitive hypomorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to make a normal gene product in normal amounts at low temperatures, but at higher temperatures to make a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity." [FBC:DOS, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000752 ! heat sensitive hypomorphic allele is_a: FBcv:0000757 ! temperature conditional hypomorphic allele - molecular evidence relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:59:43Z [Term] id: FBcv:0000760 name: temperature conditional antimorphic allele namespace: allele_class def: "An allele that makes a gene product that is antagonistic to the function of the wild-type gene product at some temperatures, but not others." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000695 ! antimorphic allele is_a: FBcv:0000748 ! temperature conditional gain of function allele relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:57:02Z [Term] id: FBcv:0000761 name: heat sensitive antimorphic allele namespace: allele_class def: "An allele that makes a gene product that is antagonistic to the function of the wild-type gene product at high temperatures, but not at lower temperatures." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000749 ! heat sensitive gain of function allele is_a: FBcv:0000760 ! temperature conditional antimorphic allele relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:54:34Z [Term] id: FBcv:0000762 name: cold sensitive antimorphic allele namespace: allele_class def: "An allele that makes a gene product that is antagonistic to the function of the wild-type gene product at cold temperatures, but not at higher temperatures." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000750 ! cold sensitive gain of function allele is_a: FBcv:0000760 ! temperature conditional antimorphic allele relationship: conditionality FBcv:0000312 ! cold sensitive [Term] id: FBcv:0000763 name: temperature conditional antimorphic allele - genetic evidence namespace: allele_class def: "An allele inferred to make a gene product that is antagonistic to the wild-type gene product at some temperatures (restrictive temperatures) but not at others (permissive temperatures) from the observation that, at the non-permissive temperatures, the phenotype over a deficiency is stronger than that over a wild-type allele, which in turn is stronger than that in the presence of a duplication of the wild-type locus." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000292 ! antimorphic allele - genetic evidence is_a: FBcv:0000760 ! temperature conditional antimorphic allele relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:55:17Z [Term] id: FBcv:0000764 name: cold sensitive antimorphic allele - genetic evidence namespace: allele_class def: "An allele inferred to make a gene product that is antagonistic to the wild-type gene product at low temperatures (restrictive temperatures) but not at high temperatures (permissive temperatures) from the observation that, at the non-permissive temperatures, the phenotype over a deficiency is stronger than that over a wild-type allele, which in turn is stronger than that in the presence of a duplication of the wild-type locus." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000762 ! cold sensitive antimorphic allele is_a: FBcv:0000763 ! temperature conditional antimorphic allele - genetic evidence relationship: conditionality FBcv:0000312 ! cold sensitive created_by: djs93 creation_date: 2012-03-22T03:58:31Z [Term] id: FBcv:0000765 name: heat sensitive antimorphic allele - genetic evidence namespace: allele_class def: "An allele inferred to make a gene product that is antagonistic to the wild-type gene product at high temperatures (restrictive temperatures) but not at lower temperatures (permissive temperatures) from the observation that, at the non-permissive temperatures, the phenotype over a deficiency is stronger than that over a wild-type allele, which in turn is stronger than that in the presence of a duplication of the wild-type locus." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000761 ! heat sensitive antimorphic allele is_a: FBcv:0000763 ! temperature conditional antimorphic allele - genetic evidence relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:59:43Z [Term] id: FBcv:0000766 name: temperature conditional antimorphic allele - molecular evidence namespace: allele_class def: "An allele that has been shown by molecular evidence to make a gene product that is antagonistic to the function of the wild-type gene product at some temperatures but not others." [FBC:DOS, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000694 ! antimorphic allele - molecular evidence is_a: FBcv:0000760 ! temperature conditional antimorphic allele relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:55:17Z [Term] id: FBcv:0000767 name: cold sensitive antimorphic allele - molecular evidence namespace: allele_class def: "An allele that has been shown by molecular evidence to make a gene product that is antagonistic to the function of the wild-type gene product at low temperatures but not higher temperatures." [FBC:DOS, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000762 ! cold sensitive antimorphic allele is_a: FBcv:0000766 ! temperature conditional antimorphic allele - molecular evidence relationship: conditionality FBcv:0000312 ! cold sensitive created_by: djs93 creation_date: 2012-03-22T03:58:31Z [Term] id: FBcv:0000768 name: heat sensitive antimorphic allele - molecular evidence namespace: allele_class def: "An allele that has been shown by molecular evidence to make a gene product that is antagonistic to the function of the wild-type gene product at high temperatures but not lower temperatures." [FBC:DOS, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000761 ! heat sensitive antimorphic allele is_a: FBcv:0000766 ! temperature conditional antimorphic allele - molecular evidence relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:59:43Z [Term] id: FBcv:0000769 name: temperature conditional neomorphic allele namespace: allele_class def: "An allele that, at some temperatures but not others, makes a gene product with a novel function or expression pattern compared to wild-type." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000697 ! neomorphic allele is_a: FBcv:0000748 ! temperature conditional gain of function allele relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:57:02Z [Term] id: FBcv:0000770 name: heat sensitive neomorphic allele namespace: allele_class def: "An allele that, at some high temperatures but not lower temperatures, makes a gene product with a novel function or expression pattern compared to wild-type." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000749 ! heat sensitive gain of function allele is_a: FBcv:0000769 ! temperature conditional neomorphic allele relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:54:34Z [Term] id: FBcv:0000771 name: cold sensitive neomorphic allele namespace: allele_class def: "An allele that, at some low temperatures but not higher temperatures, makes a gene product at with a novel function or expression pattern compared to wild-type." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000750 ! cold sensitive gain of function allele is_a: FBcv:0000769 ! temperature conditional neomorphic allele relationship: conditionality FBcv:0000312 ! cold sensitive [Term] id: FBcv:0000772 name: temperature conditional neomorphic allele - genetic evidence namespace: allele_class def: "An allele that, is inferred to make a gene product with a novel function or expression pattern compared to wild-type at some temperatures (non-permissive temperatures) but not others (permissive temperatures) based on the evidence that the phenotype at the non-permissive temperature is unaffected by extra or fewer doses of the wild-type gene." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000291 ! neomorphic allele - genetic evidence is_a: FBcv:0000769 ! temperature conditional neomorphic allele relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:55:17Z [Term] id: FBcv:0000773 name: cold sensitive neomorphic allele - genetic evidence namespace: allele_class def: "An allele that, is inferred to make a gene product with a novel function or expression pattern compared to wild-type at some low termperatures (non-permissive temperatures) but not higher temperatures (permissive temperatures), based on the evidence that the phenotype at the non-permissive temperature is unaffected by extra or fewer doses of the wild-type gene." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000771 ! cold sensitive neomorphic allele is_a: FBcv:0000772 ! temperature conditional neomorphic allele - genetic evidence relationship: conditionality FBcv:0000312 ! cold sensitive created_by: djs93 creation_date: 2012-03-22T03:58:31Z [Term] id: FBcv:0000774 name: heat sensitive neomorphic allele - genetic evidence namespace: allele_class def: "An allele that, is inferred to make a gene product with a novel function or expression pattern compared to wild-type at some high termperatures (non-permissive temperatures) but not lower temperatures (permissive temperatures), based on the evidence that the phenotype at the non-permissive temperature is unaffected by extra or fewer doses of the wild-type gene." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000770 ! heat sensitive neomorphic allele is_a: FBcv:0000772 ! temperature conditional neomorphic allele - genetic evidence relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:59:43Z [Term] id: FBcv:0000775 name: temperature conditional neomorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to produce a gene product with a novel function or expression pattern (compared to wild-type) at some temperatures but not others." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000692 ! neomorphic allele - molecular evidence is_a: FBcv:0000769 ! temperature conditional neomorphic allele relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:55:17Z [Term] id: FBcv:0000776 name: cold sensitive neomorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to produce a gene product with a novel function or expression pattern (compared to wild-type) at low temperatures but not higher temperatures." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000771 ! cold sensitive neomorphic allele is_a: FBcv:0000775 ! temperature conditional neomorphic allele - molecular evidence relationship: conditionality FBcv:0000312 ! cold sensitive created_by: djs93 creation_date: 2012-03-22T03:58:31Z [Term] id: FBcv:0000777 name: heat sensitive neomorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to produce a gene product with a novel function or expression pattern (compared to wild-type) at high temperatures but not lower temperatures." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000770 ! heat sensitive neomorphic allele is_a: FBcv:0000775 ! temperature conditional neomorphic allele - molecular evidence relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:59:43Z [Term] id: FBcv:0000778 name: temperature conditional hypermorphic allele namespace: allele_class def: "An allele that, at some temperatures but not others, makes a gene product with normal function but at higher levels or with higher activity than in wild-type." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000696 ! hypermorphic allele is_a: FBcv:0000748 ! temperature conditional gain of function allele relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:57:02Z [Term] id: FBcv:0000779 name: heat sensitive hypermorphic allele namespace: allele_class def: "An allele that, at high temperatures but not lower temperatures, makes a gene product with normal function but at higher levels or with higher activity than in wild-type." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000749 ! heat sensitive gain of function allele is_a: FBcv:0000778 ! temperature conditional hypermorphic allele relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:54:34Z [Term] id: FBcv:0000780 name: cold sensitive hypermorphic allele namespace: allele_class def: "An allele that, at low temperatures but not higher temperatures, makes a gene product with normal function but at higher levels or with higher activity than in wild-type.." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000750 ! cold sensitive gain of function allele is_a: FBcv:0000778 ! temperature conditional hypermorphic allele relationship: conditionality FBcv:0000312 ! cold sensitive [Term] id: FBcv:0000781 name: temperature conditional hypermorphic allele - genetic evidence namespace: allele_class def: "An allele inferred from genetic evidence to make a normal gene product at increased levels or with increased activity compared to wild-type, where this increased amount or activity is present at some temperatures (non-permissive temperatures) but not others (permissive temperatures), and where the genetic evidence consists of the observation that extra copies in the genome increase the expressivity and/or penetrance of the phenotype at the non-permissive temperatures." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000293 ! hypermorphic allele - genetic evidence is_a: FBcv:0000778 ! temperature conditional hypermorphic allele relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:55:17Z [Term] id: FBcv:0000782 name: cold sensitive hypermorphic allele - genetic evidence namespace: allele_class def: "An allele inferred from genetic evidence to make a normal gene product at increased levels or with increased activity compared to wild-type, where this increased amount or activity is present at low temperatures (non-permissive temperatures) but not higher temperatures (permissive temperatures), and where the genetic evidence consists of the observation that extra copies in the genome increase the expressivity and/or penetrance of the phenotype at the non-permissive temperatures." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000780 ! cold sensitive hypermorphic allele is_a: FBcv:0000781 ! temperature conditional hypermorphic allele - genetic evidence relationship: conditionality FBcv:0000312 ! cold sensitive created_by: djs93 creation_date: 2012-03-22T03:58:31Z [Term] id: FBcv:0000783 name: heat sensitive hypermorphic allele - genetic evidence namespace: allele_class def: "An allele inferred from genetic evidence to make a normal gene product at increased levels or with increased activity compared to wild-type, where this increased amount or activity is present at high temperatures (non-permissive temperatures) but not lower temperatures (permissive temperatures), and where the genetic evidence consists of the observation that extra copies in the genome increase the expressivity and/or penetrance of the phenotype at the non-permissive temperatures." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000779 ! heat sensitive hypermorphic allele is_a: FBcv:0000781 ! temperature conditional hypermorphic allele - genetic evidence relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:59:43Z [Term] id: FBcv:0000784 name: temperature conditional hypermorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to make a functionally wild-type gene product at increased levels or with increased activity where this increased expression or activity occurs at some temperatures but not others." [FBC:DOS, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000693 ! hypermorphic allele - molecular evidence is_a: FBcv:0000778 ! temperature conditional hypermorphic allele relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:55:17Z [Term] id: FBcv:0000785 name: cold sensitive hypermorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to make a functionally wild-type gene product at increased levels or with increased activity where this increased expression or activity occurs at low temperatures but not higher temperatures." [FBC:DOS, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000780 ! cold sensitive hypermorphic allele is_a: FBcv:0000784 ! temperature conditional hypermorphic allele - molecular evidence relationship: conditionality FBcv:0000312 ! cold sensitive created_by: djs93 creation_date: 2012-03-22T03:58:31Z [Term] id: FBcv:0000786 name: heat sensitive hypermorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to make a functionally wild-type gene product at increased levels or with increased activity where this increased expression or activity occurs at high temperatures but not lower temperatures." [FBC:DOS, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000779 ! heat sensitive hypermorphic allele is_a: FBcv:0000784 ! temperature conditional hypermorphic allele - molecular evidence relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:59:43Z [Term] id: FBcv:0000787 name: journal namespace: pub_type def: "A publication issued on a regular, ongoing basis containing separate research articles and other writings such as reviews, comments and conference reports." [FBC:SM, MeSH:D020492] synonym: "Periodicals" RELATED [MeSH:D020492] xref: MeSH:D020492 is_a: FBcv:0000652 ! compendium created_by: djs93 creation_date: 2012-07-10T04:08:06Z [Term] id: FBcv:0000788 name: newspaper article namespace: pub_type def: "A work consisting of a news item appearing in a general-interest newspaper or other general news periodical, containing information of current and timely interest in the field of medicine or science." [FBC:SM, MeSH:D018431] xref: MeSH:D018431 is_a: FBcv:0000189 ! publication class created_by: djs93 creation_date: 2012-07-10T04:17:34Z [Term] id: FBcv:0000789 name: sequence record namespace: pub_type def: "A record of a nucleotide or protein sequence in some standard format." [FBC:SM] is_a: FBcv:0000189 ! publication class created_by: djs93 creation_date: 2012-07-10T05:42:47Z [Term] id: FBcv:0000790 name: database namespace: pub_type def: "Work consisting of a structured file of information or a set of logically related data stored and retrieved using computer-based means." [FBC:SM, MeSH:D019991] xref: MeSH:D019991 is_a: FBcv:0000189 ! publication class created_by: djs93 creation_date: 2012-07-13T02:06:57Z [Term] id: FBcv:0000791 name: delayed aging namespace: phenotypic_class def: "A phenotype in which the aging process (GO:0007568) is slower than in wild-type." [FBC:DOC] subset: camcur is_a: FBcv:0000384 ! aging defective [Term] id: FBcv:0000792 name: premature aging namespace: phenotypic_class def: "A phenotype in which the aging process (GO:0007568) is accelerated compared to wild-type." [FBC:DOC] subset: camcur is_a: FBcv:0000384 ! aging defective [Term] id: FBcv:0000793 name: progressive namespace: temporal_qualifier def: "An adult phenotype that becomes more severe with age." [FBC:DOS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur is_a: FBcv:0000176 ! temporal qualifier created_by: djs93 creation_date: 2012-10-10T12:02:35Z [Term] id: FBcv:0000797 name: cell autonomy qualifier namespace: genotype_to_phenotype_relation def: "Cell autonomy statements describe the cellular focus of mutant phenotype, generally revealed by genetic mosaic analysis, in terms of whether the mutant has its phenotypic effect limited to, or not limited to, cells of the mutant genotype." [FBC:rd] is_a: FBcv:0000809 ! phenotype qualifier [Term] id: FBcv:0000799 name: gene descriptor is_obsolete: true [Term] id: FBcv:0000801 name: polymorphism assay is_obsolete: true [Term] id: FBcv:0000803 name: RFLP synonym: "restriction fragment length polymorphism" RELATED [] is_obsolete: true [Term] id: FBcv:0000805 name: DNA sequence variant is_obsolete: true [Term] id: FBcv:0000807 name: allele descriptor is_a: FBcv:0000013 ! descriptor [Term] id: FBcv:0000809 name: phenotype qualifier is_a: FBcv:0000005 ! qualifier [Term] id: FBcv:0000811 name: qualitative qualifier is_a: FBcv:0000809 ! phenotype qualifier [Term] id: FBcv:0000812 name: clone of cells namespace: clone_qualifier def: "A clone of cells that share a genotype." [FBC:DOS] synonym: "clone qualifier" RELATED [] is_a: FBcv:0000809 ! phenotype qualifier [Term] id: FBcv:0000813 name: nitrogen mustard namespace: origin_of_mutation def: "Mutation induced by exposure to compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-C2H2-C2H2)2NR. (Definition imported and edited from 'nitrogen mustard ; CHEBI:37598', which is related to this term.)." [CHEBI:37598, FBC:auto_generated_definition] subset: camcur synonym: "2-chloro-N-(2-chloroethyl)-N-methylethanamine" RELATED [] synonym: "CB1414" RELATED [] synonym: "HN2" RELATED [] synonym: "mechlorethamine" RELATED [] synonym: "mutation induced by nitrogen mustard exposure" EXACT [] is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000814 name: 1,4-dimethanesulfonoxybutane namespace: origin_of_mutation def: "Mutation induced by exposure to a methanesulfonate ester that is butane-1,4-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. An alkylating antineoplastic agent, it is used for the treatment of chronic myeloid leukemia (although it has been largely replaced by newer drugs). It is also used as an insect sterilant. (Definition imported and edited from 'busulfan ; CHEBI:28901', which is related to this term.)." [CHEBI:28901, FBC:auto_generated_definition] subset: camcur synonym: "busulfan" RELATED [CHEBI:28901] synonym: "CB2041" RELATED [] synonym: "mutation induced by 1,4-dimethanesulfonoxybutane exposure" EXACT [] synonym: "mutation induced by busulfan exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000815 name: p-N,N-di-(2-chloroethyl)aminophenylbutyric acid namespace: origin_of_mutation def: "Mutation induced by exposure to a nitrogen mustard that has formula C14H19Cl2NO2. (Definition imported and edited from 'chlorambucil ; CHEBI:28830', which is related to this term.)." [CHEBI:28830, FBC:auto_generated_definition] subset: camcur synonym: "CB1348" RELATED [] synonym: "chlorambucil" EXACT [CHEBI:28830] synonym: "mutation induced by chlorambucil exposure" EXACT [] synonym: "mutation induced by p-N,N-di-(2-chloroethyl)aminophenylbutyric acid exposure" EXACT [] is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0001003 name: cold sensitive amorphic allele def: "An allele that completely lacks function (i.e. whose gene productive is completely inactive) at low temperatures, but that retains at least some function at higher temperatures." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] subset: camcur is_a: FBcv:0000739 ! temperature conditional amorphic allele is_a: FBcv:0000747 ! cold sensitive loss of function allele relationship: conditionality FBcv:0000312 ! cold sensitive [Term] id: FBcv:0001315 name: beta-estradiol conditional namespace: environmental_qualifier def: "Phenotype expressed only in the presence of beta-estradiol (CHEBI:16469)." [FBC:DOS] comment: Proforma field: GA56-q. Proforma field: GA28a-q. Proforma field: GA29a-q. Proforma field: GA17-q. Proforma field: GA28b-q. Proforma field: GA29b-q. Proforma field: GAT6-q. Proforma field: GAP5-q. subset: camcur synonym: "conditional beta-estradiol" EXACT [] is_a: FBcv:0000313 ! drug conditional [Term] id: FBcv:0001324 name: endocytosis defective namespace: phenotypic_class def: "Phenotype that is a defect in endocytosis (GO:0006897). 'endocytosis' is defined as: 'A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.'" [FBC:DOS, GOC:mah, ISBN:0198506732, ISBN:0716731363] subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0001325 name: exocytosis defective namespace: phenotypic_class subset: camcur is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0001347 name: phenotype namespace: phenotypic_class def: "A defect in or loss of some anatomical structure or biological process compared to wild-type." [FBC:DOS] comment: The subclasses of this term classify Drosophila phenotypes into different common categories. They have been chosen by FlyBase to reflect phenotype terms most often reported by Drosophila researchers in the published literature. synonym: "phenotypic class" EXACT [] is_a: FBcv:0000347 ! phenotypic class [Term] id: FBcv:0001500 name: minos activity namespace: origin_of_mutation def: "Mutation induced by the transposable activity caused by Minos, a DNA transposable element. The minos element is 1.4 kilobases in length with 254 base pairs inverted terminal repeats. It specifically targets TA dinucleotides and generates a flanking duplication of 2 base pairs upon insertion. Mobilization is induced by the activity of the minos transposase." [FBC:DOS, FlyBase:FBrf0202435] subset: camcur synonym: "mutation induced by minos activity" EXACT [] is_a: FBcv:0000483 ! transposable element activity [Term] id: FBcv:0002000 name: lethal - all die before end of P-stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population at some stage or stages prior to eclosion from the pupal case (the end of the P-stage)." [FBC:DOS] comment: As the P-Stage and the 'pharate adult stage' have the same end, there is no need for a seprate term for 'lethal - all die before end of pharate adult stage. subset: camcur synonym: "lethal - all die before end of pharate adult stage" EXACT [] is_a: FBcv:0000351 ! lethal [Term] id: FBcv:0002001 name: lethal - all die before end of first instar larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the first instar larval stage." [FBC:DOS] subset: camcur is_a: FBcv:0002003 ! lethal - all die before end of second instar larval stage [Term] id: FBcv:0002002 name: lethal - all die before end of larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the larval stage." [FBC:DOS] comment: As the larval stage and third instar larval stage have the same end, there is no need for a separate term for 'lethal - all die before end of third instar larval stage'. subset: camcur synonym: "lethal - all die before end of third instar larval stage" EXACT [] is_a: FBcv:0002026 ! lethal - all die before end of prepupal stage [Term] id: FBcv:0002003 name: lethal - all die before end of second instar larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the second instar larval stage." [FBC:DOS] subset: camcur is_a: FBcv:0002002 ! lethal - all die before end of larval stage [Term] id: FBcv:0002004 name: increased mortality namespace: phenotypic_class def: "A phenotype that is an increase in the rate of death in a population at any any stage of life (during development or adulthood), over the rate seen in a wild type control population. " [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0002005 name: lethal - all die during P-stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population during the P-stage." [FBC:DOS] subset: camcur is_a: FBcv:0002000 ! lethal - all die before end of P-stage is_a: FBcv:0002010 ! majority die during P-stage [Term] id: FBcv:0002006 name: lethal - all die during first instar larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population during the first instar larval stage." [FBC:DOS] subset: camcur is_a: FBcv:0002001 ! lethal - all die before end of first instar larval stage is_a: FBcv:0002007 ! lethal - all die during larval stage is_a: FBcv:0002011 ! majority die during first instar larval stage [Term] id: FBcv:0002007 name: lethal - all die during larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population during the larval stage." [FBC:DOS] subset: camcur is_a: FBcv:0002002 ! lethal - all die before end of larval stage is_a: FBcv:0002012 ! majority die during larval stage [Term] id: FBcv:0002008 name: lethal - all die during second instar larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population during the second instar larval stage." [FBC:DOS] subset: camcur is_a: FBcv:0002003 ! lethal - all die before end of second instar larval stage is_a: FBcv:0002007 ! lethal - all die during larval stage is_a: FBcv:0002013 ! majority die during second instar larval stage [Term] id: FBcv:0002009 name: lethal - all die during third instar larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population during the third instar larval stage." [FBC:DOS] subset: camcur is_a: FBcv:0002007 ! lethal - all die during larval stage is_a: FBcv:0002014 ! majority die during third instar larval stage [Term] id: FBcv:0002010 name: majority die during P-stage namespace: phenotypic_class def: "A phenotype of a population that is the death of the majority of animals in that population during the P-stage." [] subset: camcur is_a: FBcv:0002020 ! some die during P-stage [Term] id: FBcv:0002011 name: majority die during first instar larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of the majority of animals in that population during the first instar larval stage." [FBC:DOS] subset: camcur is_a: FBcv:0002012 ! majority die during larval stage is_a: FBcv:0002021 ! some die during first instar larval stage [Term] id: FBcv:0002012 name: majority die during larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of the majority of animals in that population during the larval stage." [] subset: camcur is_a: FBcv:0002023 ! some die during larval stage [Term] id: FBcv:0002013 name: majority die during second instar larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of the majority of animals in that population during the second instar larval stage." [FBC:DOS] subset: camcur is_a: FBcv:0002012 ! majority die during larval stage is_a: FBcv:0002022 ! some die during second instar larval stage [Term] id: FBcv:0002014 name: majority die during third instar larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of the majority of animals in that population during the third instar larval stage." [FBC:DOS] subset: camcur is_a: FBcv:0002012 ! majority die during larval stage is_a: FBcv:0002024 ! some die during third instar larval stage [Term] id: FBcv:0002015 name: partially lethal namespace: phenotypic_class def: "A phenotype of a population that is the death of some significant proportion of animals in that population prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012)." [FBC:DOS, FBC:KM] subset: camcur is_a: FBcv:0002019 ! increased mortality during development [Term] id: FBcv:0002019 name: increased mortality during development namespace: phenotypic_class def: "A phenotype of a population that is the death a significant proportion of animals in that population prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012)." [FBC:DOS] is_a: FBcv:0002004 ! increased mortality [Term] id: FBcv:0002020 name: some die during P-stage namespace: phenotypic_class def: "A phenotype of a population that is the death a significant proportion of animals in that population during the P-stage." [FBC:DOS] subset: camcur is_a: FBcv:0002019 ! increased mortality during development [Term] id: FBcv:0002021 name: some die during first instar larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death a significant proportion of animals in that population during the first instar larval stage." [FBC:DOS] subset: camcur is_a: FBcv:0002023 ! some die during larval stage [Term] id: FBcv:0002022 name: some die during second instar larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death a significant proportion of animals in that population during the second instar larval stage." [FBC:DOS] subset: camcur is_a: FBcv:0002023 ! some die during larval stage [Term] id: FBcv:0002023 name: some die during larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death a significant proportion of animals in that population during the larval stage." [FBC:DOS] subset: camcur is_a: FBcv:0002019 ! increased mortality during development [Term] id: FBcv:0002024 name: some die during third instar larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death a significant proportion of animals in that population during the third instar larval stage." [FBC:DOS] subset: camcur is_a: FBcv:0002023 ! some die during larval stage [Term] id: FBcv:0002025 name: lethal - all die during pharate adult stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population during the pharate adult stage." [FBC:DOS] subset: camcur is_a: FBcv:0002005 ! lethal - all die during P-stage is_a: FBcv:0002036 ! majority die during pharate adult stage [Term] id: FBcv:0002026 name: lethal - all die before end of prepupal stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the prepupal stage." [FBC:DOS] subset: camcur is_a: FBcv:0002027 ! lethal - all die before end of pupal stage [Term] id: FBcv:0002027 name: lethal - all die before end of pupal stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the pupal stage." [FBC:DOS] subset: camcur is_a: FBcv:0002000 ! lethal - all die before end of P-stage [Term] id: FBcv:0002030 name: lethal - all die during pupal stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population during the pupal stage." [FBC:DOS] subset: camcur is_a: FBcv:0002005 ! lethal - all die during P-stage is_a: FBcv:0002027 ! lethal - all die before end of pupal stage is_a: FBcv:0002034 ! majority die during pupal stage [Term] id: FBcv:0002031 name: lethal - all die during prepupal stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population during the prepupal stage." [FBC:DOS] subset: camcur is_a: FBcv:0002005 ! lethal - all die during P-stage is_a: FBcv:0002026 ! lethal - all die before end of prepupal stage is_a: FBcv:0002035 ! majority die during prepupal stage [Term] id: FBcv:0002032 name: lethal - all die before end of embryonic stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the embryonic stage." [FBC:DOS] subset: camcur is_a: FBcv:0002001 ! lethal - all die before end of first instar larval stage [Term] id: FBcv:0002033 name: lethal - all die during embryonic stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population during the embryonic stage." [FBC:DOS] subset: camcur is_a: FBcv:0002032 ! lethal - all die before end of embryonic stage is_a: FBcv:0002037 ! majority die during embryonic stage [Term] id: FBcv:0002034 name: majority die during pupal stage namespace: phenotypic_class def: "A phenotype of a population that is the death of the majority of animals in that population during the pupal stage." [FBC:DOS] subset: camcur is_a: FBcv:0002010 ! majority die during P-stage is_a: FBcv:0002039 ! some die during pupal stage [Term] id: FBcv:0002035 name: majority die during prepupal stage namespace: phenotypic_class def: "A phenotype of a population that is the death of the majority of animals in that population during the prepual stage." [FBC:DOS] subset: camcur is_a: FBcv:0002010 ! majority die during P-stage is_a: FBcv:0002040 ! some die during prepupal stage [Term] id: FBcv:0002036 name: majority die during pharate adult stage namespace: phenotypic_class def: "A phenotype of a population that is the death of the majority of animals in that population during the pharate adult stage." [FBC:DOS] subset: camcur is_a: FBcv:0002010 ! majority die during P-stage is_a: FBcv:0002038 ! some die during pharate adult stage [Term] id: FBcv:0002037 name: majority die during embryonic stage namespace: phenotypic_class def: "A phenotype of a population that is the death of the majority of animals in that population during the embryonic stage." [FBC:DOS] comment: This term is agnostic about whether any survive to adulthood. subset: camcur is_a: FBcv:0002041 ! some die during embryonic stage [Term] id: FBcv:0002038 name: some die during pharate adult stage namespace: phenotypic_class def: "A phenotype of a population that is the death a significant proportion of animals in that population during the pharate adult stage." [FBC:DOS] subset: camcur is_a: FBcv:0002020 ! some die during P-stage [Term] id: FBcv:0002039 name: some die during pupal stage namespace: phenotypic_class def: "A phenotype of a population that is the death a significant proportion of animals in that population during the pupal stage." [FBC:DOS] subset: camcur is_a: FBcv:0002020 ! some die during P-stage [Term] id: FBcv:0002040 name: some die during prepupal stage namespace: phenotypic_class def: "A phenotype of a population that is the death a significant proportion of animals in that population during the prepual stage." [FBC:DOS] subset: camcur is_a: FBcv:0002020 ! some die during P-stage [Term] id: FBcv:0002041 name: some die during embryonic stage namespace: phenotypic_class def: "A phenotype of a population that is the death a significant proportion of animals in that population during the embryonic stage." [FBC:DOS] subset: camcur is_a: FBcv:0002019 ! increased mortality during development [Term] id: FBcv:0002042 name: lethal - all die during immature adult stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population as immature adults (after eclosion but before the end of adult stage A3 (FBdv:00006012))." [FBC:DOS] subset: camcur is_a: FBcv:0000351 ! lethal is_a: FBcv:0002050 ! majority die during immature adult stage [Term] id: FBcv:0002050 name: majority die during immature adult stage namespace: phenotypic_class def: "A phenotype of a population that is the death of the majority of animals in that population as immature adults (after eclosion but before the end of adult stage A3 (FBdv:00006012))." [FBC:DOS] subset: camcur is_a: FBcv:0002051 ! some die during immature adult stage [Term] id: FBcv:0002051 name: some die during immature adult stage namespace: phenotypic_class def: "A phenotype of a population that is the death of some significant number of animals in that population as immature adults (after eclosion but before the end of adult stage A3 (FBdv:00006012))." [FBC:DOS] subset: camcur is_a: FBcv:0002019 ! increased mortality during development [Term] id: FBcv:0003000 name: disease qualifier namespace: disease_qualifier is_a: FBcv:0000005 ! qualifier created_by: mmc46 creation_date: 2014-03-27T11:07:29Z [Term] id: FBcv:0003001 name: ameliorates namespace: disease_qualifier def: "Makes a condition better." [FBC:ST] comment: The 'ameliorates' term is used in FlyBase disease annotation when an allele interacts to remove or reduce the severity of the disease phenotype associated with a given disease model (FBC:ST). is_a: FBcv:0003000 ! disease qualifier created_by: mmc46 creation_date: 2014-03-27T11:07:29Z [Term] id: FBcv:0003002 name: DOES NOT ameliorate namespace: disease_qualifier def: "Contrary to expectation, does not make a condition better." [FBC:ST] comment: The 'DOES NOT ameliorate' term is used in FlyBase disease annotation when an allele is expected to remove or reduce the severity of the disease phenotype associated with a given disease model but fails to do so. is_a: FBcv:0003000 ! disease qualifier created_by: mmc46 creation_date: 2014-03-27T11:07:29Z [Term] id: FBcv:0003003 name: DOES NOT exacerbate namespace: disease_qualifier def: "Contrary to expectation, does not make a condition worse." [FBC:ST] comment: The 'DOES NOT exacerbate' term is used in FlyBase disease annotation when an allele is expected to makes the disease phenotype associated with a given disease model more severe but fails to do so (FBC:ST). is_a: FBcv:0003000 ! disease qualifier created_by: mmc46 creation_date: 2014-03-27T11:07:29Z [Term] id: FBcv:0003004 name: DOES NOT model namespace: disease_qualifier def: "Contrary to expectation, characteristics associated with a given condition are not recapitulated in a different system." [FBC:ST] comment: The 'DOES NOT model' term is used in FlyBase disease annotation when an allele is expected to recapitulate one or more aspects of a particular human disease phenotype in Drosophila but fails to do so (FBC:ST). is_a: FBcv:0003000 ! disease qualifier created_by: mmc46 creation_date: 2014-03-27T11:07:29Z [Term] id: FBcv:0003005 name: exacerbates namespace: disease_qualifier def: "Makes a condition worse." [FBC:ST] comment: The 'exacerbates' term is used in FlyBase disease annotation when an allele interacts to make the disease phenotype associated with a given disease model more severe (FBC:ST). is_a: FBcv:0003000 ! disease qualifier created_by: mmc46 creation_date: 2014-03-27T11:07:29Z [Term] id: FBcv:0003006 name: model of namespace: disease_qualifier def: "Characteristics associated with a given condition recapitulated in a different system." [FBC:ST] comment: The 'model of' term is used in FlyBase disease annotation when alleles (typically of fly or human genes) recapitulate one or more aspect of a human disease phenotype in Drosophila (FBC:ST). is_a: FBcv:0003000 ! disease qualifier created_by: mmc46 creation_date: 2014-03-27T11:07:29Z [Term] id: FBcv:0003007 name: site specific cleavage namespace: origin_of_mutation def: "Sequence change induced by a cleavage event that is caused by an endonuclease that recognizes and cleaves specific sequences in double stranded DNA causing double-strand breaks (DSB)." [FlyBase:FBrf0202435] subset: camcur synonym: "change induced by site specific cleavage" EXACT [] is_a: FBcv:0000452 ! origin of mutation created_by: mmc46 creation_date: 2014-03-27T11:07:29Z [Term] id: FBcv:0003008 name: CRISPR/Cas9 namespace: origin_of_mutation def: "Sequence change caused by a cleavage of a specific DNA sequence induced by CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 nuclease system. This system relies on the transcription of a chimeric guide RNA (gRNA) which directs the Cas9 endonuclease to a specified DNA sequence through basepairing to 20 nucleotide CRISPR target sites. These sites are located next to a 3 nucleotide protospacer adjacent motif (PAM) required for DNA cleavage." [FlyBase:FBrf0222128, FlyBase:FBrf0222292, FlyBase:FBrf0222617, UniProt:Q99ZW2] subset: camcur synonym: "change induced by CRISPR/Cas9 endonuclease cleavage" EXACT [] synonym: "CRISPR/Cas9 endonuclease" RELATED [] is_a: FBcv:0003007 ! site specific cleavage created_by: mmc46 creation_date: 2014-03-27T11:07:29Z [Term] id: FBcv:0003009 name: TALEN namespace: origin_of_mutation def: "Sequence change caused by the cleavage of specific DNA sequences by transcription activator-like effector nucleases (TALENs). TALEN proteins comprise a DNA binding domain fused to the catalytic domain of the FokI endonuclease. The DNA binding domain contains a repetitive region within the middle of the protein, consisting of tandem repeats of 34 amino acid segments, with each of these segments recognizing a single base pair. The specificity of the binding is determined by two hypervariable amino acids in positions 12 and 13 (repeat-variable diresidues). Cleavage requires dimerization of FokI. The endonuclease is directed to a target region by a pair of TALENs which bind to adjacent sequences separated by a spacer region, allowing dimerization and promoting cleavage." [PMID:10954606, PMID:20660643] subset: camcur synonym: "change induced by TALE endonuclease cleavage" EXACT [] synonym: "TALE endonuclease" RELATED [] is_a: FBcv:0003007 ! site specific cleavage created_by: mmc46 creation_date: 2014-03-27T11:07:29Z [Term] id: FBcv:0003010 name: phiC31 integrase namespace: origin_of_mutation def: "Sequence change caused by a site specific recombination catalyzed by the serine recombinase phiC31 integrase that recognizes a minimal high-efficiency attP recognition site of 39 base pairs and a minimal high-efficiency attB recognition site of 34 base pairs. The attP and attB sites contain imperfect inverted repeats flanking a short recombination core (TTG) that provides directionality." [FlyBase:FBrf0174693, FlyBase:FBrf0201927, UniProt:Q9T221] subset: camcur synonym: "change induced by phiC31 integrase recombination" EXACT [] is_a: FBcv:0000478 ! site specific recombination created_by: mmc46 creation_date: 2014-03-27T11:07:29Z [Term] id: FBcv:0003011 name: group descriptor namespace: group_descriptor is_a: FBcv:0000013 ! descriptor created_by: mmc46 creation_date: 2014-03-28T15:23:42Z [Term] id: FBcv:0003012 name: gene or gene product group namespace: group_descriptor def: "Genes or gene products that are acknowledged to form a natural biological group." [FBC:SM] is_a: FBcv:0003011 ! group descriptor created_by: mmc46 creation_date: 2014-03-28T15:23:42Z [Term] id: FBcv:0003013 name: gene array group namespace: group_descriptor def: "Two or more genes contiguously arranged where the individual genes are either identical in sequence, or essentially so (SO:0005851)." [FBC:SM, SO:ma] is_a: FBcv:0003012 ! gene or gene product group created_by: mmc46 creation_date: 2014-03-28T15:23:42Z [Term] id: FBcv:0003014 name: functional group namespace: group_descriptor def: "Genes whose products share a common biological and/or molecular function." [FBC:SM] is_a: FBcv:0003012 ! gene or gene product group created_by: mmc46 creation_date: 2014-03-28T15:23:42Z [Term] id: FBcv:0003015 name: gene complex group namespace: group_descriptor def: "Genes with the same location on the chromosome and whose products have a similar function." [FBC:SM, http://www.sdbonline.org/fly/aignfam/ensplitc.htm] is_a: FBcv:0003014 ! functional group created_by: mmc46 creation_date: 2014-03-28T15:23:42Z [Term] id: FBcv:0003016 name: protein complex group namespace: group_descriptor def: "Genes whose protein products form a macromolecular complex (GO:0043234)." [FBC:SM, GOC:go_curators] is_a: FBcv:0003014 ! functional group created_by: mmc46 creation_date: 2014-03-28T15:23:42Z [Term] id: FBcv:0003017 name: pathway group namespace: group_descriptor def: "Genes whose products act in a specified signal transduction or metabolic pathway." [FBC:SM] is_a: FBcv:0003014 ! functional group created_by: mmc46 creation_date: 2014-03-28T15:23:42Z [Term] id: FBcv:0003018 name: process group namespace: group_descriptor def: "Genes whose products act in a specified biological process." [FBC:SM] is_a: FBcv:0003014 ! functional group created_by: mmc46 creation_date: 2014-03-28T15:23:42Z [Term] id: FBcv:0003019 name: I-element activity namespace: origin_of_mutation def: "Mutation caused by the transposable activity caused by the I-element, a non-LTR retrotransposon. The I-element is 5371 base pairs long. Mobilization is induced by the activity of the I-element transposase." [FlyBase:FBrf0202435] subset: camcur synonym: "mutation induced by I-element activity" EXACT [] is_a: FBcv:0000483 ! transposable element activity created_by: mmc46 creation_date: 2014-09-16T13:30:48Z [Term] id: FBcv:0003020 name: Stalker element activity namespace: origin_of_mutation def: "Mutation caused by the transposable activity caused by the Stalker element, a LTR retrotransposon. Mobilization is induced by the activity of the stalker element transposase." [FlyBase:FBrf0202435] subset: camcur synonym: "mutation induced by Stalker element activity" EXACT [] is_a: FBcv:0000483 ! transposable element activity created_by: mmc46 creation_date: 2014-09-16T13:30:48Z [Term] id: FBcv:0010000 name: living stock comment: Consider - FBsv:0000002. is_obsolete: true [Term] id: FBcv:0010001 name: molecular extract comment: Consider - FBsv:0000003. is_obsolete: true [Term] id: FBcv:0010002 name: preserved specimen comment: Consider - FBsv:0000005. is_obsolete: true [Term] id: FBcv:0010003 name: E cytotype stock is_obsolete: true [Term] id: FBcv:0010004 name: M cytotype stock is_obsolete: true [Term] id: FBcv:0010005 name: genomic DNA comment: Consider - FBsv:0000004. is_obsolete: true [Term] id: FBcv:0010006 name: ethanol-preserved specimen comment: Consider - FBsv:0000007. is_obsolete: true [Term] id: FBcv:0010007 name: pinned specimen is_obsolete: true [Term] id: FBcv:0010009 name: fluorescent balancer comment: Consider - FBsv:0001010. is_obsolete: true [Term] id: FBcv:0010010 name: lacZ balancer comment: Consider - FBsv:0001011. is_obsolete: true [Term] id: FBcv:0010011 name: laboratory wild-type stock is_obsolete: true [Term] id: FBcv:0010012 name: collection comment: Consider - FBsv:0000100. is_obsolete: true [Term] id: FBcv:0010013 name: stock center collection comment: Consider - FBsv:0000101. is_obsolete: true [Term] id: FBcv:0010014 name: laboratory collection comment: Consider - FBsv:0000102. is_obsolete: true [Term] id: FBcv:0010015 name: Saxton laboratory is_obsolete: true [Term] id: FBcv:0010016 name: Garcia-Bellido laboratory comment: Consider - FBsv:0000109. is_obsolete: true [Term] id: FBcv:0010017 name: Nusslein-Volhard laboratory comment: Consider - FBsv:0000108. is_obsolete: true [Term] id: FBcv:0010018 name: Carpenter laboratory comment: Consider - FBsv:0000110. is_obsolete: true [Term] id: FBcv:0010019 name: Artavanis laboratory synonym: "Harvard Medical School Exelixis Drosophila Collection" RELATED [] is_obsolete: true [Term] id: FBcv:0010020 name: Exelixis Drosophila Stock Collection at Harvard Medical School comment: Consider - FBsv:0000105. synonym: "Artavanis-Tsakonas laboratory" RELATED [] is_obsolete: true [Term] id: FBcv:0010021 name: Bloomington Drosophila Stock Center comment: Consider - FBsv:0000103. synonym: "BDSC" RELATED [] synonym: "Bloomington" EXACT [] synonym: "BSC" RELATED [] is_obsolete: true [Term] id: FBcv:0010022 name: San Diego Drosophila Species Stock Center comment: Consider - FBsv:0000106. synonym: "Drosophila species stock center" RELATED [] synonym: "species stock center" EXACT [] synonym: "Tucson" RELATED [] is_obsolete: true [Term] id: FBcv:0010023 name: Szeged Drosophila Stock Centre synonym: "Szeged" RELATED [] is_obsolete: true [Term] id: FBcv:0010024 name: Drosophila Genetic Resource Center comment: Consider - FBsv:0000104. synonym: "DGRC" RELATED [] synonym: "Kyoto" RELATED [] synonym: "Kyoto stock center" RELATED [] is_obsolete: true [Typedef] id: BFO:0000060 name: precedes namespace: FlyBase_miscellaneous_CV comment: X precedes Y iff: end(X) before_or_simultaneous_with start(Y) synonym: "ends_before" EXACT [] holds_over_chain: ends_during BFO:0000060 holds_over_chain: happens_during BFO:0000060 is_transitive: true is_a: RO:0002089 ! starts_before inverse_of: preceded_by ! preceded_by [Typedef] id: RO:0002081 name: before_or_simultaneous_with namespace: FlyBase_miscellaneous_CV comment: Primitive instance level timing relation between events synonym: "<=" EXACT [] [Typedef] id: RO:0002082 name: simultaneous_with namespace: FlyBase_miscellaneous_CV comment: t1 simultaneous_with t2 iff:= t1 before_or_simultaneous_with t2 and not (t1 before t2) is_transitive: true is_a: RO:0002081 ! before_or_simultaneous_with [Typedef] id: RO:0002083 name: before namespace: FlyBase_miscellaneous_CV comment: t1 before t2 iff:= t1 before_or_simulataneous_with t2 and not (t1 simultaeous_with t2) is_transitive: true is_a: RO:0002081 ! before_or_simultaneous_with [Typedef] id: RO:0002084 name: during_which_ends namespace: FlyBase_miscellaneous_CV comment: Perviously used http://purl.obolibrary.org/obo/RO_0002122 - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. inverse_of: ends_during ! ends_during [Typedef] id: RO:0002085 name: encompasses namespace: FlyBase_miscellaneous_CV comment: Previously had ID http://purl.obolibrary.org/obo/RO_0002124 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range. is_transitive: true is_a: RO:0002084 ! during_which_ends is_a: RO:0002088 ! during_which_starts inverse_of: happens_during ! happens_during [Typedef] id: RO:0002086 name: ends_after namespace: FlyBase_miscellaneous_CV comment: X ends_after Y iff: end(Y) before_or_simultaneous_with end(X) holds_over_chain: ends_during preceded_by is_transitive: true [Typedef] id: RO:0002088 name: during_which_starts namespace: FlyBase_miscellaneous_CV comment: Previously had ID http://purl.obolibrary.org/obo/RO_0002123 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range. inverse_of: starts_during ! starts_during [Typedef] id: RO:0002089 name: starts_before namespace: FlyBase_miscellaneous_CV holds_over_chain: starts_during BFO:0000060 is_transitive: true [Typedef] id: RO:0002351 name: has_member namespace: FlyBase_miscellaneous_CV [Typedef] id: conditionality name: conditionality [Typedef] id: decreased_in_magnitude_relative_to name: decreased_in_magnitude_relative_to def: "q1 decreased_in_magnitude_relative_to q2 if and only if magnitude(q1) < magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale." [PATOC:CJM] comment: This relation is used to determine the 'directionality' of relative qualities such as 'decreased strength', relative to the parent type, 'strength'.\nThis relation is used to determine the 'directionality' of relative qualities such as 'decreased strength', relative to the parent type, 'strength'. is_transitive: true is_a: different_in_magnitude_relative_to ! different_in_magnitude_relative_to [Typedef] id: different_in_magnitude_relative_to name: different_in_magnitude_relative_to def: "q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale." [PATOC:CJM] [Typedef] id: ends_at_start_of name: immediately_precedes namespace: FlyBase_miscellaneous_CV comment: X immediately_precedes_Y iff: end(X) simultaneous_with start(Y) synonym: "ends_at_start_of" EXACT [] xref: RO:0002090 is_a: BFO:0000060 ! precedes inverse_of: starts_at_end_of ! immediately_preceded_by [Typedef] id: ends_during name: ends_during namespace: external namespace: gene_ontology comment: X ends_during Y iff: ((start(Y) before_or_simultaneous_with end(X)) AND end(X) before_or_simultaneous_with end(Y). xref: RO:0002093 [Typedef] id: happens_during name: happens_during namespace: external namespace: gene_ontology comment: X happens_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (end(X) before_or_simultaneous_with end(Y)) xref: RO:0002092 is_transitive: true is_a: ends_during ! ends_during is_a: starts_during ! starts_during [Typedef] id: has_cross_section name: has_cross_section def: "s3 has_cross_section s3 if and only if : there exists some 2d plane that intersects the bearer of s3, and the impression of s3 upon that plane has shape quality s2." [PATOC:CJM] comment: Example: a spherical object has the quality of being spherical, and the spherical quality has_cross_section round.\nExample: a spherical object has the quality of being spherical, and the spherical quality has_cross_section round. [Typedef] id: has_part name: has_part namespace: external namespace: relationship xref: BFO:0000051 xref: OBO_REL:has_part is_transitive: true [Typedef] id: has_role name: has role namespace: FlyBase_miscellaneous_CV [Typedef] id: http://purl.obolibrary.org/obo/scratch_70595e1b_dde4_4b0a_90c3_dfa9c95d30ab name: has_age namespace: FlyBase_miscellaneous_CV is_functional: true [Typedef] id: increased_in_magnitude_relative_to name: increased_in_magnitude_relative_to def: "q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale." [PATOC:CJM] comment: This relation is used to determine the 'directionality' of relative qualities such as 'increased strength', relative to the parent type, 'strength'.\nThis relation is used to determine the 'directionality' of relative qualities such as 'increased strength', relative to the parent type, 'strength'. is_transitive: true is_a: different_in_magnitude_relative_to ! different_in_magnitude_relative_to [Typedef] id: inheres_in name: inheres_in namespace: FlyBase_miscellaneous_CV xref: RO:0000052 [Typedef] id: negatively_regulates name: negatively regulates namespace: external xref: RO:0002212 is_a: regulates ! regulates [Typedef] id: occurs_in name: occurs in namespace: external namespace: gene_ontology xref: BFO:0000066 holds_over_chain: part_of occurs_in transitive_over: part_of ! part_of [Typedef] id: part_of name: part_of namespace: external namespace: relationship synonym: "part_of" EXACT [] xref: BFO:0000050 xref: OBO_REL:part_of is_transitive: true is_a: happens_during ! happens_during inverse_of: has_part ! has_part [Typedef] id: positively_regulates name: positively regulates namespace: external xref: RO:0002213 is_a: regulates ! regulates [Typedef] id: preceded_by name: preceded_by namespace: FlyBase_miscellaneous_CV comment: X preceded_by Y iff: end(Y) before_or_simultaneous_with start(X) synonym: "proceeds" EXACT [] synonym: "starts_after" EXACT [] xref: BFO:0000062 xref: OBO_REL:preceded_by holds_over_chain: happens_during preceded_by holds_over_chain: starts_during preceded_by is_transitive: true is_a: RO:0002086 ! ends_after created_by: djs93 creation_date: 2009-10-09T10:00:53Z [Typedef] id: qualifier name: qualifier namespace: FlyBase_miscellaneous_CV comment: temporary placeholder - this means that Obol could not infer the correct relation [Typedef] id: reciprocal_of name: reciprocal_of def: "q1 reciprocal_of q2 if and only if : q1 and q2 are relational qualities and a phenotype e q1 e2 mutually implies a phenotype e2 q2 e." [PATOC:CJM] comment: There are frequently two ways to state the same thing: we can say 'spermatocyte lacks asters' or 'asters absent from spermatocyte'. In this case the quality is 'lacking all parts of type' - it is a (relational) quality of the spermatocyte, and it is with respect to instances of 'aster'. One of the popular requirements of PATO is that it continue to support 'absent', so we need to relate statements which use this quality to the 'lacking all parts of type' quality.\nThere are frequently two ways to state the same thing: we can say 'spermatocyte lacks asters' or 'asters absent from spermatocyte'. In this case the quality is 'lacking all parts of type' - it is a (relational) quality of the spermatocyte, and it is with respect to instances of 'aster'. One of the popular requirements of PATO is that it continue to support 'absent', so we need to relate statements which use this quality to the 'lacking all parts of type' quality. [Typedef] id: regulates name: regulates namespace: external namespace: gene_ontology xref: RO:0002211 transitive_over: part_of ! part_of [Typedef] id: similar_in_magnitude_relative_to name: similar_in_magnitude_relative_to def: "q1 similar_in_magnitude_relative_to q2 if and only if magnitude(q1) =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale." [PATOC:CJM] [Typedef] id: singly_occurring_form_of name: singly_occurring_form_of comment: PATO divides qualities between normal (monadic, singly-occurring) qualities and relational qualities. Relational qualities stand in the 'towards' relation with respect to some additional entity. For example, The sensitivity of an eye towards red light. In some cases we want to represent a quality such as 'protruding' in both monadic and relational branches. We use this relation to link them.\nPATO divides qualities between normal (monadic, singly-occurring) qualities and relational qualities. Relational qualities stand in the 'towards' relation with respect to some additional entity. For example, The sensitivity of an eye towards red light. In some cases we want to represent a quality such as 'protruding' in both monadic and relational branches. We use this relation to link them. synonym: "monadic_form_of" EXACT [] [Typedef] id: starts_at_end_of name: immediately_preceded_by namespace: FlyBase_miscellaneous_CV comment: X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y) synonym: "starts_at_end_of" EXACT [] xref: RO:0002087 is_a: preceded_by ! preceded_by [Typedef] id: starts_during name: starts_during namespace: external namespace: gene_ontology comment: X starts_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (start(X) before_or_simultaneous_with end(Y)) xref: RO:0002091 [Typedef] id: towards name: towards namespace: FlyBase_miscellaneous_CV comment: temporary placeholder - may be placed in OBO_REL; with relational qualities, the additional argument is the 'towards' argument; eg sensitivity towards chlorine. Relation binding a relational quality or disposition to the relevant type of entity.