format-version: 1.2 date: 28:04:2010 13:29 saved-by: louis auto-generated-by: OBO-Edit 2.0 default-namespace: ido_namespace remark: alpha-version: please send comments to topalis[at]imbb.forth.gr format-version: 1.2 format-version: 1.2 format-version: 1.2 format-version: 1.2 [Term] id: CHEBI:16130 name: DDT alt_id: MIRO:10000157 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:39000 ! sodium channel modulator [Term] id: CHEBI:17514 name: cyanide alt_id: MIRO:10000292 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:38500 ! mitochondrial complex IV electron transport inhibitor [Term] id: CHEBI:18172 name: fluoroacetate alt_id: MIRO:10000298 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000297 ! aconitase inhibitor [Term] id: CHEBI:18723 name: nicotine alt_id: MIRO:10000170 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000159 ! nicotinic acetylcholine receptor agontist/antagonist [Term] id: CHEBI:23457 name: cyclodiene organochlorine alt_id: MIRO:10000102 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000100 ! GABA-gated chloride channel antagonist [Term] id: CHEBI:24942 name: juvenile hormone mimic alt_id: MIRO:10000181 def: "A chemical substance which is being used as insecticide." [PT:PT] xref: IRAC:eClassification "http://www.irac-online.org/eClassification/" is_a: MIRO:10000030 ! growth inhibitor is_a: MIRO:10000169 ! active insecticidal substance [Term] id: CHEBI:25355 name: mitochondrial complex III electron transport inhibitor alt_id: MIRO:10000267 def: "A chemical substance which inhibits mitochondrial complex III electron transport chain." [PT:PT] synonym: "inhibition of coupling site II" EXACT [] xref: IRAC:eClassification "http://www.irac-online.org/eClassification/" is_a: IDOMAL:0000001 ! role [Term] id: CHEBI:2555 name: aldicarb alt_id: MIRO:10000003 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:25708 name: organophosphate alt_id: MIRO:10000031 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:38462 ! acetylcholine esterase inhibitor [Term] id: CHEBI:2630 name: hydramethylnon alt_id: MIRO:10000269 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:25355 ! mitochondrial complex III electron transport inhibitor [Term] id: CHEBI:26413 name: pyrethroid alt_id: MIRO:10000112 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:39000 ! sodium channel modulator [Term] id: CHEBI:2653 name: aminocarb alt_id: MIRO:10000005 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:2665 name: amitraz alt_id: MIRO:10000266 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000265 ! octopaminergic agonist [Term] id: CHEBI:2674 name: amodiaquine alt_id: IDOMAL:0000225 def: "A 4-aminoquinoline schizontocidal drug." [KL:KL] comment: All synonyms reflect proprietary names based on the list appearing on "Chemotherapy of Malaria", 2nd edition, WHO 1981. synonym: "Basoquin" EXACT [] synonym: "Cam-aqi" EXACT [] synonym: "Camoquin" EXACT [] synonym: "Camoquinal" EXACT [] synonym: "Flavoquin" EXACT [] synonym: "Fluroquin" EXACT [] synonym: "Miaquine" EXACT [] is_a: IDOMAL:0000204 ! 4-aminoquinoline relationship: part_of IDOMAL:0000145 ! artesunate and amodiaquine combination created_by: louis creation_date: 2008-05-15T07:46:25Z [Term] id: CHEBI:27815 name: pyrethrin alt_id: MIRO:10000156 def: "A chemical substance which is being used as insecticide." [PT:PT] synonym: "pyrethrum" EXACT [] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:39000 ! sodium channel modulator [Term] id: CHEBI:27928 name: parathion alt_id: MIRO:10000074 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:28201 name: rotenone alt_id: MIRO:10000281 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000274 ! mitochondrial complex I electron transport inhibitor [Term] id: CHEBI:2953 name: azinphos-methyl alt_id: MIRO:10000035 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:2959 name: azocyclotin alt_id: MIRO:10000229 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:39292 ! organotin miticide [Term] id: CHEBI:3014 name: benfuracarb alt_id: MIRO:10000007 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:30260 name: cyromazine alt_id: MIRO:10000256 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000255 ! moulting disruptor in Diptera [Term] id: CHEBI:3093 name: bifenthrin alt_id: MIRO:10000117 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:3218 name: buprofezin alt_id: MIRO:10000254 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000001 ! chitin biosynthesis inhibitor [Term] id: CHEBI:32253 name: transfluthrin alt_id: MIRO:10000154 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:32888 name: lindane alt_id: MIRO:10000105 alt_id: MIRO:10000107 def: "A chemical substance which is being used as insecticide." [PT:PT] synonym: "gamma-hexachlorocyclohexane" EXACT [] is_a: CHEBI:23457 ! cyclodiene organochlorine [Term] id: CHEBI:33755 name: tetronic acid derivative alt_id: MIRO:10000285 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000284 ! lipid synthesis inhibitor [Term] id: CHEBI:3390 name: carbaryl alt_id: MIRO:10000010 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:34304 name: fenobucarb alt_id: MIRO:10000014 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:3436 name: cartap alt_id: MIRO:10000173 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000159 ! nicotinic acetylcholine receptor agontist/antagonist [Term] id: CHEBI:34520 name: acephate alt_id: MIRO:10000032 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:34556 name: bendiocarb alt_id: MIRO:10000006 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:34572 name: bioallethrin alt_id: MIRO:10000114 alt_id: MIRO:10000118 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:34611 name: carbofuran alt_id: MIRO:10000011 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:34620 name: chinomethionat alt_id: MIRO:10000312 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:38809 ! ryanodine receptor modulator [Term] id: CHEBI:34623 name: chlordane alt_id: MIRO:10000103 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:23457 ! cyclodiene organochlorine [Term] id: CHEBI:34631 name: chlorpyrifos alt_id: MIRO:10000040 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:34632 name: chlorpyrifos-methyl alt_id: MIRO:10000041 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:34682 name: diazinon alt_id: MIRO:10000045 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:34690 name: dichlorvos alt_id: MIRO:10000046 def: "A chemical substance which is being used as insecticide." [PT:PT] synonym: "DDVP" RELATED [] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:34692 name: dicofol alt_id: MIRO:10000314 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:38809 ! ryanodine receptor modulator [Term] id: CHEBI:34696 name: dieldrin alt_id: MIRO:10000160 def: "A chemical substance which is being used as insecticide." [PT:PT] xref: IUPAC:(1R\,4S\,4aS\,5R\,6R\,7S\,8S\,8aR)-1\,2\,3\,4\,10\,10-hexachloro-1\,4\,4a\,5\,6\,7\,8\,8a-octahydro-6\,7-epoxy-1\,4\:5\,8-dimethanonaphthalene is_a: CHEBI:23457 ! cyclodiene organochlorine [Term] id: CHEBI:34703 name: diflubenzuron alt_id: MIRO:10000243 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:38494 ! benzoylurea [Term] id: CHEBI:34714 name: dimethoate alt_id: MIRO:10000048 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:34733 name: EPN alt_id: MIRO:10000051 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:34757 name: fenitrothion alt_id: MIRO:10000056 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:34760 name: fensulfothion alt_id: MIRO:10000057 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:34761 name: fenthion alt_id: MIRO:10000058 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:34763 name: flucythrinate alt_id: MIRO:10000139 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:34785 name: heptachlor alt_id: MIRO:10000106 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:23457 ! cyclodiene organochlorine [Term] id: CHEBI:34801 name: isoxathion alt_id: MIRO:10000064 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:34837 name: methidathion alt_id: MIRO:10000068 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:34911 name: permethrin alt_id: MIRO:10000144 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:34917 name: phenthoate alt_id: MIRO:10000076 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:34938 name: propoxur alt_id: MIRO:10000023 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:35005 name: tetrachlorvinphos alt_id: MIRO:10000095 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:35048 name: xylylcarb alt_id: MIRO:10000028 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:35883 name: phosphine alt_id: MIRO:10000294 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:38500 ! mitochondrial complex IV electron transport inhibitor [Term] id: CHEBI:3638 name: chloroquine alt_id: IDOMAL:0000224 def: "A 4-aminoquinoline schizontocidal drug." [KL:KL] comment: All synonyms reflect proprietary names based on the list appearing on "Chemotherapy of Malaria", 2nd edition, WHO 1981. synonym: "Aralen" EXACT [] synonym: "Avloclor" EXACT [] synonym: "Bemaphate" EXACT [] synonym: "Chinamine" EXACT [] synonym: "Chlorquim" EXACT [] synonym: "Cidanchin" EXACT [] synonym: "Delagil" EXACT [] synonym: "Gontochin" EXACT [] synonym: "Imagon" EXACT [] synonym: "Iroquin" EXACT [] synonym: "Klorokin" EXACT [] synonym: "Luprochin" EXACT [] synonym: "Malarex" EXACT [] synonym: "Matalets" EXACT [] synonym: "Nivaquin" EXACT [] synonym: "Nivaquin B" EXACT [] synonym: "Resochin" EXACT [] synonym: "Resochine" EXACT [] synonym: "Resoquine" EXACT [] synonym: "Sanoquin" EXACT [] synonym: "Tanakan" EXACT [] synonym: "Tresochin" EXACT [] synonym: "Trochin" EXACT [] is_a: IDOMAL:0000204 ! 4-aminoquinoline relationship: agent_in IDOMAL:0000122 ! chemoprophylaxis relationship: part_of IDOMAL:0000144 ! artesunate and chloroquine combination relationship: part_of IDOMAL:0000155 ! sulfadoxine-pyrimethamine plus chloroquine created_by: louis creation_date: 2008-05-15T07:46:25Z [Term] id: CHEBI:38449 name: methoxyfenozide alt_id: MIRO:10000261 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:38456 ! moulting disruptor via ecdysone agonist [Term] id: CHEBI:38450 name: chromafenozide alt_id: MIRO:10000259 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:38456 ! moulting disruptor via ecdysone agonist [Term] id: CHEBI:38451 name: halofenozide alt_id: MIRO:10000260 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:38456 ! moulting disruptor via ecdysone agonist [Term] id: CHEBI:38452 name: tebufenozide alt_id: MIRO:10000262 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:38456 ! moulting disruptor via ecdysone agonist [Term] id: CHEBI:38456 name: moulting disruptor via ecdysone agonist alt_id: MIRO:10000257 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000101 ! moulting disruptor [Term] id: CHEBI:38462 name: acetylcholine esterase inhibitor alt_id: MIRO:10000000 def: "A chemical substance which inhibits acetylcholine esterase." [PT:PT] xref: IRAC:eClassification "http://www.irac-online.org/eClassification/" is_a: IDOMAL:0000001 ! role [Term] id: CHEBI:38463 name: alanycarb alt_id: MIRO:10000004 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:38465 name: butocarboxim alt_id: MIRO:10000008 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:38470 name: butoxycarboxim alt_id: MIRO:10000009 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:38473 name: azadirachtin alt_id: MIRO:10000264 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:38456 ! moulting disruptor via ecdysone agonist [Term] id: CHEBI:38476 name: carbosulfan alt_id: MIRO:10000012 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:38483 name: ethiofencarb alt_id: MIRO:10000013 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:38491 name: formetanate alt_id: MIRO:10000015 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:38494 name: benzoylurea alt_id: MIRO:10000241 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000001 ! chitin biosynthesis inhibitor [Term] id: CHEBI:38495 name: aluminium phosphide alt_id: MIRO:10000290 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:38500 ! mitochondrial complex IV electron transport inhibitor [Term] id: CHEBI:38500 name: mitochondrial complex IV electron transport inhibitor alt_id: MIRO:10000288 def: "A chemical substance which inhibits mitochondrial complex IV electron transport chain." [PT:PT] xref: IRAC:eClassification "http://www.irac-online.org/eClassification/" is_a: IDOMAL:0000001 ! role [Term] id: CHEBI:38504 name: furathiocarb alt_id: MIRO:10000016 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:38505 name: isoprocarb alt_id: MIRO:10000017 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:38508 name: methiocarb alt_id: MIRO:10000018 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:38537 name: metolcarb alt_id: MIRO:10000020 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:38539 name: oxamyl alt_id: MIRO:10000021 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:38548 name: thiodicarb alt_id: MIRO:10000024 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:38549 name: thiofanox alt_id: MIRO:10000025 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:38569 name: trimethacarb alt_id: MIRO:10000026 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:38571 name: XMC alt_id: MIRO:10000027 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:38576 name: triazamate alt_id: MIRO:10000029 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:38462 ! acetylcholine esterase inhibitor [Term] id: CHEBI:38578 name: azamethiphos alt_id: MIRO:10000033 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38587 name: azinphos-ethyl alt_id: MIRO:10000034 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38588 name: cadusafos alt_id: MIRO:10000036 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38590 name: chlorethoxyfos alt_id: MIRO:10000037 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38591 name: fluacrypyrim alt_id: MIRO:10000273 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:25355 ! mitochondrial complex III electron transport inhibitor [Term] id: CHEBI:38592 name: acequinocyl alt_id: MIRO:10000271 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:25355 ! mitochondrial complex III electron transport inhibitor [Term] id: CHEBI:38593 name: fenazaquin alt_id: MIRO:10000275 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000274 ! mitochondrial complex I electron transport inhibitor [Term] id: CHEBI:38598 name: chlorfenvinphos alt_id: MIRO:10000038 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38603 name: chlormephos alt_id: MIRO:10000039 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38604 name: pyrimidifen alt_id: MIRO:10000277 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000274 ! mitochondrial complex I electron transport inhibitor [Term] id: CHEBI:38621 name: cyanophos alt_id: MIRO:10000043 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38624 name: demeton-S-methyl alt_id: MIRO:10000044 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38626 name: pyridaben alt_id: MIRO:10000278 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000274 ! mitochondrial complex I electron transport inhibitor [Term] id: CHEBI:38628 name: tolfenpyrad alt_id: MIRO:10000280 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000274 ! mitochondrial complex I electron transport inhibitor [Term] id: CHEBI:38630 name: indoxacarb alt_id: MIRO:10000283 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:38634 ! voltage-dependent sodium channel blocker [Term] id: CHEBI:38634 name: voltage-dependent sodium channel blocker alt_id: MIRO:10000282 def: "A chemical substance which blocks voltage-dependent sodium channels." [PT:PT] xref: IRAC:eClassification "http://www.irac-online.org/eClassification/" is_a: IDOMAL:0000001 ! role [Term] id: CHEBI:38639 name: spirodiclofen alt_id: MIRO:10000286 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:33755 ! tetronic acid derivative [Term] id: CHEBI:38640 name: spiromesifen alt_id: MIRO:10000287 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:33755 ! tetronic acid derivative [Term] id: CHEBI:38658 name: dicrotophos alt_id: MIRO:10000047 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38659 name: dimethylvinphos alt_id: MIRO:10000049 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38661 name: disulfoton alt_id: MIRO:10000050 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38663 name: ethion alt_id: MIRO:10000052 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38665 name: ethoprophos alt_id: MIRO:10000053 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38677 name: famphur alt_id: MIRO:10000054 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38680 name: fenamiphos alt_id: MIRO:10000055 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38689 name: fonofos alt_id: MIRO:10000059 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38692 name: fosthiazate alt_id: MIRO:10000060 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38693 name: heptenophos alt_id: MIRO:10000061 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38704 name: isopropyl O-(methoxyaminothio-phosphoryl)salicylate alt_id: MIRO:10000063 def: "A chemical substance which is being used as insecticide." [PT:PT] synonym: "isocarbophos" RELATED [] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38718 name: mecarbam alt_id: MIRO:10000066 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38721 name: methamidophos alt_id: MIRO:10000067 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38725 name: mevinphos alt_id: MIRO:10000069 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38728 name: monocrotophos alt_id: MIRO:10000070 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38729 name: naled alt_id: MIRO:10000071 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38730 name: omethoate alt_id: MIRO:10000072 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38735 name: oxydemeton-methyl alt_id: MIRO:10000073 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38746 name: parathion-methyl alt_id: MIRO:10000075 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38764 name: phorate alt_id: MIRO:10000077 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38786 name: phosmet alt_id: MIRO:10000079 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38798 name: flubendiamide alt_id: MIRO:10000307 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:38809 ! ryanodine receptor modulator [Term] id: CHEBI:38809 name: ryanodine receptor modulator alt_id: MIRO:10000306 def: "A chemical substance which modulates ryanodine receptor." [PT:PT] xref: IRAC:eClassification "http://www.irac-online.org/eClassification/" is_a: IDOMAL:0000001 ! role [Term] id: CHEBI:38812 name: phoxim alt_id: MIRO:10000081 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38813 name: benzoximate alt_id: MIRO:10000310 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:38809 ! ryanodine receptor modulator [Term] id: CHEBI:38832 name: phosphamidon alt_id: MIRO:10000080 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38843 name: pirimiphos-methyl alt_id: MIRO:10000082 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38845 name: profenofos alt_id: MIRO:10000083 def: "A chemical substance which is being used as insecticide." [PT:PT] synonym: "bromofos" EXACT [] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38858 name: propaphos alt_id: MIRO:10000084 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38864 name: propetamphos alt_id: MIRO:10000085 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38876 name: pyraclofos alt_id: MIRO:10000087 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38881 name: pyridaphenthion alt_id: MIRO:10000088 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38887 name: pyridalyl alt_id: MIRO:10000316 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:38809 ! ryanodine receptor modulator [Term] id: CHEBI:38945 name: sulfotep alt_id: MIRO:10000090 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38949 name: sulprofos alt_id: MIRO:10000091 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38951 name: tebupirimfos alt_id: MIRO:10000092 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38954 name: temephos alt_id: MIRO:10000093 def: "A chemical substance which is being used as insecticide." [PT:PT] synonym: "OMS-786" RELATED [] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38960 name: terbufos alt_id: MIRO:10000094 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38962 name: thiometon alt_id: MIRO:10000096 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38963 name: triazophos alt_id: MIRO:10000097 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:38990 name: vamidothion alt_id: MIRO:10000099 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:39000 name: sodium channel modulator alt_id: MIRO:10000111 def: "A chemical substance which modulates sodium channels." [PT:PT] xref: IRAC:eClassification "http://www.irac-online.org/eClassification/" is_a: IDOMAL:0000001 ! role [Term] id: CHEBI:3903 name: coumaphos alt_id: MIRO:10000042 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:39091 name: acrinathrin alt_id: MIRO:10000113 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39115 name: bioallethrin S-cyclopentenyl alt_id: MIRO:10000119 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39118 name: d-trans allethrin alt_id: MIRO:10000116 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39137 name: d-cis-trans allethrin alt_id: MIRO:10000115 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39163 name: acetamiprid alt_id: MIRO:10000162 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:39182 ! neonicotinoid [Term] id: CHEBI:39171 name: nitenpyram alt_id: MIRO:10000166 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:39182 ! neonicotinoid [Term] id: CHEBI:39175 name: thiacloprid alt_id: MIRO:10000167 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:39182 ! neonicotinoid [Term] id: CHEBI:39178 name: clothianidin alt_id: MIRO:10000163 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:39182 ! neonicotinoid [Term] id: CHEBI:39182 name: neonicotinoid alt_id: MIRO:10000161 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000159 ! nicotinic acetylcholine receptor agontist/antagonist [Term] id: CHEBI:39183 name: dinotefuran alt_id: MIRO:10000164 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:39182 ! neonicotinoid [Term] id: CHEBI:39185 name: thiamethoxam alt_id: MIRO:10000168 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:39182 ! neonicotinoid [Term] id: CHEBI:39188 name: bensultap alt_id: MIRO:10000172 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000159 ! nicotinic acetylcholine receptor agontist/antagonist [Term] id: CHEBI:39211 name: spinosad alt_id: MIRO:10000175 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000174 ! allosteric agonist of nicotinic acetylcholine receptor [Term] id: CHEBI:39213 name: avermectin and milbemycin alt_id: MIRO:10000177 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000176 ! chloride channel activator [Term] id: CHEBI:39214 name: abamectin alt_id: MIRO:10000178 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:39213 ! avermectin and milbemycin [Term] id: CHEBI:39225 name: milbemectin alt_id: MIRO:10000180 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:39213 ! avermectin and milbemycin [Term] id: CHEBI:39233 name: emamectin benzoate alt_id: MIRO:10000179 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:39213 ! avermectin and milbemycin [Term] id: CHEBI:39234 name: hydroprene alt_id: MIRO:10000184 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000183 ! juvenile hormone analogue [Term] id: CHEBI:39243 name: kinoprene alt_id: MIRO:10000185 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000183 ! juvenile hormone analogue [Term] id: CHEBI:39255 name: methoprene alt_id: MIRO:10000186 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000183 ! juvenile hormone analogue [Term] id: CHEBI:39260 name: pyriproxyfen alt_id: MIRO:10000190 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:24942 ! juvenile hormone mimic [Term] id: CHEBI:39275 name: methyl bromide alt_id: MIRO:10000193 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:39276 ! fumigant [Term] id: CHEBI:39276 name: fumigant alt_id: MIRO:10000191 def: "A chemical substance which acts as a fumigant." [PT:PT] xref: IRAC:eClassification "http://www.irac-online.org/eClassification/" is_a: IDOMAL:0000001 ! role [Term] id: CHEBI:39280 name: bioresmethrin alt_id: MIRO:10000120 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39283 name: cycloprothrin alt_id: MIRO:10000121 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39285 name: chloropicrin alt_id: MIRO:10000196 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:39276 ! fumigant [Term] id: CHEBI:39287 name: sulfuryl fluoride alt_id: MIRO:10000198 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:39276 ! fumigant [Term] id: CHEBI:39292 name: organotin miticide alt_id: MIRO:10000228 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000224 ! oxidative phosphorylation inhibitor [Term] id: CHEBI:39294 name: fenbutatin oxide alt_id: MIRO:10000231 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:39292 ! organotin miticide [Term] id: CHEBI:39299 name: diafenthiuron alt_id: MIRO:10000226 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000224 ! oxidative phosphorylation inhibitor [Term] id: CHEBI:39300 name: propargite alt_id: MIRO:10000233 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000224 ! oxidative phosphorylation inhibitor [Term] id: CHEBI:39314 name: beta-cyfluthrin alt_id: MIRO:10000123 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39315 name: clofentezine alt_id: MIRO:10000208 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000206 ! growth inhibitor sensu acarea [Term] id: CHEBI:39323 name: gamma-cyhalothrin alt_id: MIRO:10000126 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39325 name: lambda-cyhalothrin alt_id: MIRO:10000125 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39326 name: hexythiazox alt_id: MIRO:10000210 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000206 ! growth inhibitor sensu acarea [Term] id: CHEBI:39329 name: etoxazole alt_id: MIRO:10000212 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000206 ! growth inhibitor sensu acarea [Term] id: CHEBI:39330 name: tetradifon alt_id: MIRO:10000234 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000224 ! oxidative phosphorylation inhibitor [Term] id: CHEBI:39331 name: alpha-cypermethrin alt_id: MIRO:10000128 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39332 name: beta-cypermethrin alt_id: MIRO:10000129 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39333 name: theta-cypermethrin alt_id: MIRO:10000130 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39334 name: zeta-cypermethrin alt_id: MIRO:10000131 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39341 name: phenothrin [(1R)-trans- isomer] alt_id: MIRO:10000132 alt_id: MIRO:10000145 def: "A chemical substance which is being used as insecticide." [PT:PT] synonym: "sumithrin" EXACT [] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39346 name: esfenvalerate alt_id: MIRO:10000135 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39347 name: chlorfenapyr alt_id: MIRO:10000237 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000236 ! uncoupler of oxidative phosphorylation [Term] id: CHEBI:39348 name: etofenprox alt_id: MIRO:10000136 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39349 name: DNOC alt_id: MIRO:10000238 def: "A chemical substance which is being used as insecticide." [PT:PT] synonym: "4,6-dinitro-o-cresol" EXACT [] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000236 ! uncoupler of oxidative phosphorylation [Term] id: CHEBI:39353 name: fenpropathrin alt_id: MIRO:10000137 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39361 name: flumethrin alt_id: MIRO:10000140 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39367 name: tau-fluvalinate alt_id: MIRO:10000141 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39368 name: halfenprox alt_id: MIRO:10000142 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39370 name: chlorfluazuron alt_id: MIRO:10000242 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:38494 ! benzoylurea [Term] id: CHEBI:39374 name: fluazuron alt_id: MIRO:10000244 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:38494 ! benzoylurea [Term] id: CHEBI:39375 name: flucycloxuron alt_id: MIRO:10000245 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:38494 ! benzoylurea [Term] id: CHEBI:39382 name: flufenoxuron alt_id: MIRO:10000246 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:38494 ! benzoylurea [Term] id: CHEBI:39383 name: hexaflumuron alt_id: MIRO:10000247 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:38494 ! benzoylurea [Term] id: CHEBI:39384 name: lufenuron alt_id: MIRO:10000248 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:38494 ! benzoylurea [Term] id: CHEBI:39385 name: novaluron alt_id: MIRO:10000249 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:38494 ! benzoylurea [Term] id: CHEBI:39386 name: noviflumuron alt_id: MIRO:10000250 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:38494 ! benzoylurea [Term] id: CHEBI:39387 name: teflubenzuron alt_id: MIRO:10000251 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:38494 ! benzoylurea [Term] id: CHEBI:39388 name: triflumuron alt_id: MIRO:10000252 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:38494 ! benzoylurea [Term] id: CHEBI:39389 name: imiprothrin alt_id: MIRO:10000143 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39391 name: prallethrin alt_id: MIRO:10000146 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39392 name: rU 15525 alt_id: MIRO:10000148 def: "A chemical substance which is being used as insecticide." [PT:PT] synonym: "kadethrin" RELATED [] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39393 name: silafluofen alt_id: MIRO:10000149 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39397 name: tetramethrin alt_id: MIRO:10000151 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39399 name: tetramethrin [(1R)- isomers] alt_id: MIRO:10000152 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39400 name: tralomethrin alt_id: MIRO:10000153 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39402 name: ZXI 8901 alt_id: MIRO:10000155 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39404 name: empenthrin [(EZ)- (1R)- isomers] alt_id: MIRO:10000134 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:39411 name: chloropropylate alt_id: MIRO:10000235 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000224 ! oxidative phosphorylation inhibitor [Term] id: CHEBI:4034 name: cyfluthrin alt_id: MIRO:10000122 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:4035 name: cyhalothrin alt_id: MIRO:10000124 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:4036 name: cyhexatin alt_id: MIRO:10000230 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:39292 ! organotin miticide [Term] id: CHEBI:4042 name: cypermethrin alt_id: MIRO:10000127 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:4388 name: deltamethrin alt_id: MIRO:10000133 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:4791 name: endosulfan alt_id: MIRO:10000104 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:23457 ! cyclodiene organochlorine [Term] id: CHEBI:5009 name: fenoxycarb alt_id: MIRO:10000188 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:24942 ! juvenile hormone mimic [Term] id: CHEBI:5011 name: fenpyroximate alt_id: MIRO:10000276 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000274 ! mitochondrial complex I electron transport inhibitor [Term] id: CHEBI:5014 name: fenvalerate alt_id: MIRO:10000138 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:5063 name: fipronil alt_id: MIRO:10000110 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000109 ! fipronil / phenylpyrazole [Term] id: CHEBI:5870 name: imidacloprid alt_id: MIRO:10000165 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:39182 ! neonicotinoid [Term] id: CHEBI:6009 name: isofenphos alt_id: MIRO:10000062 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:6651 name: malathion alt_id: MIRO:10000065 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:6835 name: methomyl alt_id: MIRO:10000019 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:6842 name: methoxychlor alt_id: MIRO:10000158 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:39000 ! sodium channel modulator [Term] id: CHEBI:6908 name: trichlorfon alt_id: MIRO:10000098 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:8121 name: phosalone alt_id: MIRO:10000078 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:8248 name: pirimicarb alt_id: MIRO:10000022 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000002 ! carbamate [Term] id: CHEBI:8712 name: quinalphos alt_id: MIRO:10000089 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: CHEBI:8811 name: resmethrin alt_id: MIRO:10000147 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CHEBI:9422 name: tebufenpyrad alt_id: MIRO:10000279 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000274 ! mitochondrial complex I electron transport inhibitor [Term] id: CHEBI:9430 name: tefluthrin alt_id: MIRO:10000150 def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:26413 ! pyrethroid [Term] id: CL:0000000 name: cell alt_id: IDOMAL:0000713 def: "Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." [CARO:mah] is_a: IDOMAL:0002458 ! anatomical structure created_by: guest creation_date: 2009-11-25T04:23:56Z [Term] id: CL:0000081 name: blood cell alt_id: IDOMAL:0000714 def: "A cell found predominately in the blood." [CL:00000081] is_a: CL:0000988 ! hematopoetic cell created_by: guest creation_date: 2009-11-25T05:53:16Z [Term] id: CL:0000084 name: T cell alt_id: IDOMAL:0000722 def: "A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." [GOC:add, ISBN:0781735149] synonym: "" RELATED [] is_a: CL:0000542 ! lymphocyte relationship: participates_in GO:0002457 ! T cell antigen processing and presentation created_by: guest creation_date: 2009-11-25T06:08:50Z [Term] id: CL:0000094 name: granulocyte alt_id: IDOMAL:0000752 def: "A leukocyte with abundant granules in the cytoplasm." [CL:0000094] is_a: CL:0000766 ! myeloid leukocyte created_by: guest creation_date: 2009-12-07T06:05:36Z [Term] id: CL:0000232 name: erythrocyte alt_id: IDOMAL:0000716 def: "A red blood cell. In mammals, mature erythrocytes are non-nucleated, biconcave disks containing hemoglobin whose function is to transport oxygen." [MESH:A.11.118.290] synonym: "RBC" EXACT [] synonym: "red blood cell" EXACT [] is_a: CL:0000081 ! blood cell created_by: guest creation_date: 2009-11-25T05:53:23Z [Term] id: CL:0000234 name: phagocyte alt_id: IDOMAL:0000781 def: "Any cell capable of ingesting particulate matter via phagocytosis." [CL:0000234] is_a: IDOMAL:0000001 ! role created_by: guest creation_date: 2009-11-26T09:02:34Z [Term] id: CL:0000236 name: B cell alt_id: IDOMAL:0000633 def: "A lymphocyte of B lineage with the phenotype CD19-positive and surface immunoglobulin-positive." [GOC:add, ISBN:0781735149] synonym: "B lymphocyte" EXACT [] synonym: "B-cell" EXACT [] synonym: "B-lymphocyte" EXACT [] is_a: CL:0000945 ! lymphocyte of B cell lineage relationship: participates_in GO:0002312 ! B cell activation during immune response relationship: participates_in GO:0002450 ! B cell antigen processing and presentation created_by: guest creation_date: 2009-11-24T10:12:50Z [Term] id: CL:0000451 name: dendritic cell alt_id: IDOMAL:0000377 def: "A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." [GOC:add, ISBN:0781735149] synonym: "interdigitating cell" RELATED [] synonym: "veiled cell" RELATED [] is_a: CL:0000738 ! leukocyte created_by: guest creation_date: 2009-11-22T06:55:35Z [Term] id: CL:0000492 name: CD4-positive helper T cell alt_id: IDOMAL:0000728 def: "A CD4-positive, alpha-beta T cell that cooperates with other lymphocytes via direct contact or cytokine release to initiate a variety of immune functions." [GOC:add, ISBN:0781735149, MESH:A.11.118.637.555.567.569.200.400., XX:PAM-ADD] synonym: "CD4-positive helper T lymphocyte" EXACT [] synonym: "CD4-positive helper T-cell" EXACT [] synonym: "CD4-positive helper T-lymphocyte" EXACT [] synonym: "CD4-positive T-helper cell" EXACT [] is_a: CL:0000912 ! helper T cell created_by: guest creation_date: 2009-11-25T08:34:27Z [Term] id: CL:0000542 name: lymphocyte alt_id: IDOMAL:0000718 def: "A cell of the B cell, T cell, or natural killer cell lineage." [GOC:add, ISBN:0781735149] is_a: CL:0000738 ! leukocyte created_by: guest creation_date: 2009-11-25T06:01:44Z [Term] id: CL:0000545 name: T-helper 1 cell alt_id: IDOMAL:0000384 def: "A CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma." [XX:PAM-ADD] synonym: "helper T cell type 1" EXACT [] synonym: "Th1 cell" EXACT [] synonym: "Th1 T lymphocyte" EXACT [] synonym: "Th1 T-cell" EXACT [] synonym: "Th1 T-lymphocyte" EXACT [] is_a: CL:0000492 ! CD4-positive helper T cell relationship: participates_in IDOMAL:0000470 ! CD8-positive, alpha-beta cytotoxic T cell activation during immune response relationship: participates_in IDOMAL:0000471 ! suppression of T-helper 2 cell mediated immune response relationship: participates_in IDOMAL:0000472 ! suppression of T-helper 1 cell mediated immune response relationship: participates_in IDOMAL:0000811 ! T-helper 1 cell mediated cytokine production created_by: guest creation_date: 2009-11-22T07:13:15Z [Term] id: CL:0000546 name: T-helper 2 cell alt_id: IDOMAL:0000385 def: "A CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive and produces interleukin-4." [XX:PAM-ADD] synonym: "helper T cell type 2" EXACT [] synonym: "Th2 cell" EXACT [] synonym: "Th2 T cell" EXACT [] synonym: "Th2 T lymphocyte" EXACT [] synonym: "Th2 T-cell" EXACT [] synonym: "Th2 T-lymphocyte" EXACT [] is_a: CL:0000492 ! CD4-positive helper T cell relationship: participates_in IDOMAL:0000471 ! suppression of T-helper 2 cell mediated immune response relationship: participates_in IDOMAL:0000472 ! suppression of T-helper 1 cell mediated immune response relationship: participates_in IDOMAL:0000812 ! T-helper 2 cell mediated cytokine production created_by: guest creation_date: 2009-11-22T07:17:28Z [Term] id: CL:0000623 name: natural killer cell alt_id: IDOMAL:0000374 def: "A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells." [GOC:add, ISBN:0781735149, PIMD:15771571] synonym: "large granular lymphocyte" BROAD [] synonym: "NK cell" EXACT [] synonym: "null cell" BROAD [] is_a: CL:0000542 ! lymphocyte relationship: participates_in GO:0043320 ! natural killer cell degranulation relationship: participates_in IDOMAL:0000078 ! antibody-dependent cell-mediated cytotoxic response relationship: participates_in IDOMAL:0000276 ! natural killer cell activation during immune response relationship: participates_in IDOMAL:0000788 ! interferon-gamma production created_by: guest creation_date: 2009-11-22T06:54:30Z [Term] id: CL:0000624 name: CD4-positive, alpha-beta T cell alt_id: IDOMAL:0000826 def: "A mature alpha-beta T cell that expresses an alpha-beta T cell receptor and the CD4 coreceptor." [CL:0000624] synonym: "CD4-positive, alpha-beta T lymphocyte" EXACT [] synonym: "CD4-positive, alpha-beta T-cell" EXACT [] synonym: "CD4-positive, alpha-beta T-lymphocyte" EXACT [] is_a: CL:0000791 ! mature alpha-beta T cell created_by: guest creation_date: 2009-12-03T09:46:14Z [Term] id: CL:0000625 name: CD8-positive, alpha-beta T cell alt_id: IDOMAL:0000827 def: "A T cell expressing an alpha-beta T cell receptor and the CD8 coreceptor." [CL:0000625] synonym: "CD8-positive, alpha-beta T lymphocyte" EXACT [] synonym: "CD8-positive, alpha-beta T-cell" EXACT [] synonym: "CD8-positive, alpha-beta T-lymphocyte" EXACT [] is_a: CL:0000791 ! mature alpha-beta T cell created_by: guest creation_date: 2009-12-03T09:46:14Z [Term] id: CL:0000738 name: leukocyte alt_id: IDOMAL:0000715 def: "A nucleated cell of the myeloid or lymphoid lineages, found in blood or other tissue." [GOC:add] synonym: "immune cell" EXACT [] synonym: "leucocyte" EXACT [] synonym: "white blood cell" EXACT [] is_a: CL:0000988 ! hematopoetic cell created_by: guest creation_date: 2009-11-25T05:53:16Z [Term] id: CL:0000766 name: myeloid leukocyte alt_id: IDOMAL:0000719 def: "A cell of the monocyte, granulocyte, or mast cell lineage." [CL:0000766] is_a: CL:0000738 ! leukocyte created_by: guest creation_date: 2009-11-25T06:01:44Z [Term] id: CL:0000775 name: neutrophil alt_id: IDOMAL:0000787 def: "Any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes." [CL:0000775] synonym: "neutrocyte" EXACT [] synonym: "neutrophil leucocyte" EXACT [] synonym: "neutrophil leukocyte" EXACT [] synonym: "neutrophilic leucocyte" EXACT [] synonym: "neutrophilic leukocyte" EXACT [] is_a: CL:0000094 ! granulocyte relationship: has_role CL:0000234 ! phagocyte relationship: participates_in IDOMAL:0000078 ! antibody-dependent cell-mediated cytotoxic response created_by: guest creation_date: 2009-11-28T11:18:49Z [Term] id: CL:0000782 name: myeloid dendritic cell alt_id: IDOMAL:0000775 def: "A dendritic cell of the myeloid lineage." [CL:0000782] synonym: "DC1" EXACT [] synonym: "mDC" EXACT [] synonym: "myeloid DC" EXACT [] is_a: CL:0000990 ! conventional dendritic cell relationship: has_role CL:0000234 ! phagocyte relationship: participates_in GO:0002277 ! myeloid dendritic cell activation during immune response created_by: guest creation_date: 2009-12-07T07:04:56Z [Term] id: CL:0000784 name: plasmacytoid dendritic cell alt_id: IDOMAL:0000796 def: "A dendritic cell type of distinct morphology, localization, and surface marker expression from other dendritic cell types and associated with early stage immune responses, particularly the release of physiologically abundant amounts of type I interferons in response to infection." [CL:0000784] synonym: "DC2" EXACT [] synonym: "lymphoid dendritic cell" EXACT [] synonym: "pDC" EXACT [] synonym: "plasmacytoid DC" EXACT [] synonym: "plasmacytoid monocyte" EXACT [] synonym: "T-associated plasma cell" EXACT [] is_a: CL:0000451 ! dendritic cell relationship: has_role CL:0000234 ! phagocyte relationship: participates_in GO:0002271 ! plasmacytoid dendritic cell activation during immune response created_by: guest creation_date: 2009-12-07T07:09:31Z [Term] id: CL:0000789 name: alpha-beta T cell alt_id: IDOMAL:0000815 def: "A T cell that expresses an alpha-beta T cell receptor complex." [CL:0000789] synonym: "alpha-beta T lymphocyte" EXACT [] synonym: "alpha-beta T-cell" EXACT [] synonym: "alpha-beta T-lymphocyte" EXACT [] is_a: CL:0000084 ! T cell created_by: guest creation_date: 2009-12-03T09:38:05Z [Term] id: CL:0000791 name: mature alpha-beta T cell alt_id: IDOMAL:0000825 def: "A alpha-beta T cell that has a mature phenotype." [CL:0000791] synonym: "mature alpha-beta T lymphocyte" EXACT [] synonym: "mature alpha-beta T-cell" EXACT [] synonym: "mature alpha-beta T-lymphocyte" EXACT [] is_a: CL:0000789 ! alpha-beta T cell created_by: guest creation_date: 2009-12-03T09:42:56Z [Term] id: CL:0000794 name: CD8-positive, alpha-beta cytotoxic T cell alt_id: IDOMAL:0000615 def: "A CD8-positive, alpha-beta T cell that is capable of killing target cells in an antigen specific manner with the phenotype perforin-positive and granzyme B-positive." [GOC:add, ISBN:0781735149, XX:PAM-ADD] synonym: "CD8-positive, alpha-beta cytotoxic T lymphocyte" EXACT [] synonym: "CD8-positive, alpha-beta cytotoxic T-cell" EXACT [] synonym: "CD8-positive, alpha-beta cytotoxic T-lymphocyte" EXACT [] synonym: "cytotoxic T cell" BROAD [] synonym: "cytotoxic T lymphocyte" BROAD [] synonym: "cytotoxic T-cell" BROAD [] synonym: "cytotoxic T-lymphocyte" BROAD [] is_a: CL:0000910 ! cytotoxic T cell relationship: participates_in IDOMAL:0000395 ! CD8-positive, alpha-beta cytotoxic T cell degranulation relationship: participates_in IDOMAL:0000470 ! CD8-positive, alpha-beta cytotoxic T cell activation during immune response created_by: guest creation_date: 2009-11-23T06:35:21Z [Term] id: CL:0000798 name: gamma-delta T cell alt_id: IDOMAL:0000712 def: "A T cell that expresses a gamma-delta T cell receptor complex." [GOC:add, ISBN:0781735149] synonym: "gamma-delta T lymphocyte" EXACT [] synonym: "gamma-delta T-cell" EXACT [] synonym: "gamma-delta T-lymphocyte" EXACT [] is_a: CL:0000084 ! T cell relationship: participates_in IDOMAL:0000069 ! gamma-delta T cell mediated immune response created_by: guest creation_date: 2009-11-25T02:35:45Z [Term] id: CL:0000815 name: regulatory T cell alt_id: IDOMAL:0000468 def: "A T cell which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release." [GOC:add] synonym: "regulatory T lymphocyte" EXACT [] synonym: "regulatory T-cell" EXACT [] synonym: "regulatory T-lymphocyte" EXACT [] synonym: "suppressor T cell" BROAD [] synonym: "suppressor T lymphocyte" BROAD [] synonym: "suppressor T-cell" BROAD [] synonym: "suppressor T-lymphocyte" BROAD [] is_a: CL:0000084 ! T cell relationship: participates_in IDOMAL:0000759 ! regulatory T cell mediated immune response created_by: guest creation_date: 2009-11-23T09:58:25Z [Term] id: CL:0000899 name: T-helper 17 cell alt_id: IDOMAL:0000744 def: "CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17." [CL:0000899] synonym: "helper T cell type 17" EXACT [] synonym: "Th17 cell" EXACT [] synonym: "Th17 T cell" EXACT [] synonym: "Th17 T lymphocyte" EXACT [] synonym: "Th17 T-cell" EXACT [] synonym: "Th17 T-lymphocyte" EXACT [] is_a: CL:0000492 ! CD4-positive helper T cell created_by: guest creation_date: 2009-12-03T10:04:53Z [Term] id: CL:0000910 name: cytotoxic T cell alt_id: IDOMAL:0000726 def: "A mature T cell that differentiated and acquired cytotoxic function with the phenotype perforin-positive and granzyme-B positive." [XX:PAM-ADD] synonym: "cytotoxic T lymphocyte" EXACT [] synonym: "cytotoxic T-cell" EXACT [] synonym: "cytotoxic T-lymphocyte" EXACT [] is_a: CL:0000911 ! effector T cell created_by: guest creation_date: 2009-11-25T08:12:01Z [Term] id: CL:0000911 name: effector T cell alt_id: IDOMAL:0000723 def: "A differentiated T cell with the ability to traffic to peripheral tissues that has acquired helper or cytotoxic functions." [XX:PAM-ADD] synonym: "effector T lymphocyte" EXACT [] synonym: "effector T-cell" EXACT [] synonym: "effector T-lymphocyte" RELATED [] is_a: CL:0000084 ! T cell created_by: guest creation_date: 2009-11-25T08:00:31Z [Term] id: CL:0000912 name: helper T cell alt_id: IDOMAL:0000727 def: "A effector T cell that provides help in the form of secreted cytokines to other immune cells." [XX:PAM-ADD] synonym: "helper T lymphocyte" EXACT [] synonym: "helper T-cell" EXACT [] synonym: "helper T-lymphocyte" EXACT [] synonym: "T-helper cell" EXACT [] is_a: CL:0000911 ! effector T cell created_by: guest creation_date: 2009-11-25T08:12:01Z [Term] id: CL:0000945 name: lymphocyte of B cell lineage alt_id: IDOMAL:0000720 def: "A lymphocyte of B lineage is a lymphocyte that expresses CD19 (P15391/CD19_HUMAN;PIRSF016630) on the cell surface. An additional defining characteristic is the commitment to express an immunoglobulin complex." [GOC:add, ISBN:0781735149, XX:RHS] is_a: CL:0000542 ! lymphocyte created_by: guest creation_date: 2009-11-25T06:08:50Z [Term] id: CL:0000988 name: hematopoetic cell alt_id: IDOMAL:0000379 def: "A cell of a hematopoietic lineage." [GOC:add] synonym: "haematopoietic cell" EXACT [] synonym: "haemopoietic cell" EXACT [] synonym: "hemopoietic cell" EXACT [] is_a: CL:0000000 ! cell created_by: guest creation_date: 2009-11-25T05:49:15Z [Term] id: CL:0000990 name: conventional dendritic cell alt_id: IDOMAL:0000062 def: "Conventional dendritic cell is a leukocyte that has a high plasma membrane amount of CD11c and lacks plasma membrane part CD19, CD3, CD34, and CD56." [CL:0000990] synonym: "conventional DC" EXACT [] is_a: CL:0000451 ! dendritic cell created_by: Ioana creation_date: 2009-12-16T05:41:26Z [Term] id: GO:0002250 name: adaptive immune response alt_id: IDOMAL:0000013 def: "An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory)." [GO:0002250] is_a: IDOMAL:0000006 ! host immune response created_by: guest creation_date: 2009-11-20T01:54:15Z [Term] id: GO:0002263 name: cell activation during immune response alt_id: IDOMAL:0000817 def: "A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GO:0002263] is_a: GO:0009987 ! cellular process created_by: guest creation_date: 2009-12-08T10:14:43Z [Term] id: GO:0002271 name: plasmacytoid dendritic cell activation during immune response alt_id: IDOMAL:0000037 def: "A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GO:0002271] is_a: IDOMAL:0000295 ! dendritic cell activation during immune response relationship: part_of IDOMAL:0000614 ! phagocyte activation during immune response created_by: Ioana creation_date: 2009-12-16T05:09:32Z [Term] id: GO:0002275 name: myeloid cell activation during immune response alt_id: IDOMAL:0000695 def: "A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GO:0002275] synonym: "myeloid DC activation during immune response" EXACT [] is_a: GO:0002366 ! leukocyte activation during immune response created_by: guest creation_date: 2009-12-09T10:07:10Z [Term] id: GO:0002277 name: myeloid dendritic cell activation during immune response alt_id: IDOMAL:0000837 def: "The change in morphology and behavior of a myeloid dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [GO:0002277] is_a: IDOMAL:0000061 ! conventional dendritic cell activation during immune response relationship: part_of IDOMAL:0000614 ! phagocyte activation during immune response created_by: guest creation_date: 2009-12-09T10:15:10Z [Term] id: GO:0002281 name: macrophage activation during immune response alt_id: IDOMAL:0000294 def: "A change in the morphology or behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [GO:0002281] is_a: GO:0002275 ! myeloid cell activation during immune response relationship: part_of IDOMAL:0000390 ! T-helper 1 cell mediated immune response relationship: part_of IDOMAL:0000614 ! phagocyte activation during immune response created_by: guest creation_date: 2009-11-22T02:59:48Z [Term] id: GO:0002285 name: lymphocyte activation during immune response alt_id: IDOMAL:0000792 def: "A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [GO:0002285] is_a: GO:0002366 ! leukocyte activation during immune response created_by: guest creation_date: 2009-11-30T12:20:03Z [Term] id: GO:0002286 name: T cell activation during immune response alt_id: IDOMAL:0000358 def: "A change in the morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response." [GO:0002286] synonym: "T lymphocyte activation during immune response" EXACT [] synonym: "T-cell activation during immune response" EXACT [] synonym: "T-lymphocyte activation during immune response" EXACT [] is_a: GO:0002285 ! lymphocyte activation during immune response created_by: guest creation_date: 2009-11-22T03:36:05Z [Term] id: GO:0002312 name: B cell activation during immune response alt_id: IDOMAL:0000309 def: "The change in morphology and behaviour of a mature or immature B cell during immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific." [GO:0002312] synonym: "B lymphocyte activation during immune response" EXACT [] synonym: "B-cell activation during immune response" EXACT [] synonym: "B-lymphocyte activation during immune response" EXACT [] is_a: GO:0002285 ! lymphocyte activation during immune response relationship: part_of IDOMAL:0000391 ! T-helper 2 cell mediated immune response relationship: part_of IDOMAL:0000748 ! B cell mediated immune response created_by: guest creation_date: 2009-11-22T03:02:28Z [Term] id: GO:0002366 name: leukocyte activation during immune response alt_id: IDOMAL:0000791 def: "A change in the morphology and behaviour of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [GO:0002366] synonym: "immune cell activation during immune response" EXACT [] synonym: "leucocyte activation during immune response" EXACT [] is_a: GO:0002263 ! cell activation during immune response created_by: guest creation_date: 2009-11-30T12:11:41Z [Term] id: GO:0002367 name: cytokine production during immune response alt_id: IDOMAL:0000777 def: "The appearance of cytokine due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels." [GO:0002367] is_a: GO:0002440 ! production of molecular mediators of immune response created_by: guest creation_date: 2009-11-26T08:19:22Z [Term] id: GO:0002381 name: immunoglobulin production during immune response alt_id: IDOMAL:0000751 def: "The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels." [GO:0002381] synonym: "antibody production during immune response" EXACT [] is_a: GO:0002440 ! production of molecular mediators of immune response relationship: part_of IDOMAL:0000748 ! B cell mediated immune response created_by: guest creation_date: 2009-11-26T02:01:47Z [Term] id: GO:0002440 name: production of molecular mediators of immune response alt_id: IDOMAL:0000750 def: "The synthesis or release of any molecular mediator of the immune response following an immunological stimulus, resulting in an increase in its intracellular or extracellular levels." [GO:0002440] is_a: IDOMAL:0000561 ! host immune effector process created_by: guest creation_date: 2009-11-26T01:57:10Z [Term] id: GO:0002450 name: B cell antigen processing and presentation alt_id: IDOMAL:0000831 def: "The process by which a B cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GO:0002450] synonym: "B lymphocyte antigen processing and presentation" EXACT [] synonym: "B-cell antigen processing and presentation" EXACT [] synonym: "B-lymphocyte antigen processing and presentation" EXACT [] is_a: GO:0019882 ! antigen processing and presentation created_by: guest creation_date: 2009-12-08T11:42:21Z [Term] id: GO:0002457 name: T cell antigen processing and presentation alt_id: IDOMAL:0000835 def: "The process by which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GO:0002457] synonym: "T lymphocyte antigen processing and presentation" EXACT [] synonym: "T-cell antigen processing and presentation" EXACT [] synonym: "T-lymphocyte antigen processing and presentation" EXACT [] is_a: GO:0019882 ! antigen processing and presentation created_by: guest creation_date: 2009-12-08T11:42:21Z [Term] id: GO:0002468 name: dendritic cell antigen processing and presentation alt_id: IDOMAL:0000832 def: "The process by which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GO:0002468] is_a: GO:0019882 ! antigen processing and presentation created_by: guest creation_date: 2009-12-08T11:42:21Z [Term] id: GO:0002472 name: macrophage antigen processing and presentation alt_id: IDOMAL:0000833 def: "The process by which a macrophage expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GO:0002472] is_a: GO:0019882 ! antigen processing and presentation created_by: guest creation_date: 2009-12-08T11:42:21Z [Term] id: GO:0002473 name: non-professional antigen presenting cell antigen processing and presentation alt_id: IDOMAL:0000834 def: "The process by which a non-professional antigen presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. Non-professional antigen presenting cells include all cell types but dendritic cells, B cells, T cells, monocytes, macrophages, and neutrophils." [GO:0002473] is_a: GO:0019882 ! antigen processing and presentation created_by: guest creation_date: 2009-12-08T11:42:21Z [Term] id: GO:0002679 name: respiratory burst during defense response alt_id: IDOMAL:0000156 def: "A phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals." [GO:0002679] is_a: IDOMAL:0000804 ! host metabolic process created_by: guest creation_date: 2009-11-20T06:59:48Z [Term] id: GO:0002747 name: antigen processing and presentation following phagocytosis alt_id: IDOMAL:0000818 def: "Antigen processing and presentation which is initiated by uptake of antigen via phagocytosis." [GO:0002747] is_a: GO:0019882 ! antigen processing and presentation created_by: guest creation_date: 2009-12-08T11:29:20Z [Term] id: GO:0002749 name: antigen processing and presentation initiated by toll-like receptor mediated phagocytosis of antigen alt_id: IDOMAL:0000828 def: "Antigen processing and presentation which is initiated by phagocytosis of antigen bound directly or indirectly to a cell surface toll-like receptor (TLR)." [GO:0002749] synonym: "antigen processing and presentation initiated by TLR mediated phagocytosis of antigen" EXACT [] is_a: GO:0002747 ! antigen processing and presentation following phagocytosis created_by: guest creation_date: 2009-12-08T11:31:34Z [Term] id: GO:0006807 name: nitrogen compound metabolic process alt_id: IDOMAL:0000805 def: "The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds; includes nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium." [GO:0006807] synonym: "nitrogen compound metabolism" EXACT [] is_a: IDOMAL:0000804 ! host metabolic process created_by: guest creation_date: 2009-11-30T05:42:33Z [Term] id: GO:0006809 name: nitric oxide biosynthetic process alt_id: IDOMAL:0000160 def: "The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water." [GO:0006809] synonym: "nitric oxide anabolism" EXACT [] synonym: "nitric oxide biosynthesis" EXACT [] synonym: "nitric oxide formation" EXACT [] synonym: "nitric oxide synthesis" EXACT [] synonym: "NO anabolism" EXACT [] synonym: "NO biosynthesis" EXACT [] synonym: "NO formation" EXACT [] synonym: "NO synthesis" EXACT [] is_a: GO:0046209 ! nitric oxide metabolic process relationship: part_of GO:0045087 ! innate immune response relationship: part_of IDOMAL:0000150 ! lysosome independent killing created_by: guest creation_date: 2009-11-20T06:59:56Z [Term] id: GO:0006897 name: endocytosis alt_id: IDOMAL:0000020 def: "A type of vesicle-mediated transport in which cells take up external materials or membrane constituents by the invagination of small region of the plasma membrane to form a new membrane-bounded vesicle." [GO:0006897] is_a: IDOMAL:0001054 ! process of malaria host created_by: guest creation_date: 2009-11-20T02:35:08Z [Term] id: GO:0006909 name: phagocytosis alt_id: IDOMAL:0000060 def: "The process whereby phagocytes engulf external particulate material. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles." [GO:0006909] is_a: GO:0006897 ! endocytosis relationship: part_of IDOMAL:0002357 ! immune response created_by: guest creation_date: 2009-11-20T02:50:41Z [Term] id: GO:0008037 name: cell recognition alt_id: IDOMAL:0000649 def: "The process by which a cell in a multicellular organism interprets its surroundings." [GO:0008037] is_a: GO:0009987 ! cellular process created_by: guest creation_date: 2009-11-30T11:39:27Z [Term] id: GO:0008219 name: cell death alt_id: IDOMAL:0000814 def: "The specific activation or halting process within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death." [GO:0008219] is_a: GO:0009987 ! cellular process created_by: guest creation_date: 2009-12-08T09:44:52Z [Term] id: GO:0008228 name: opsonization alt_id: IDOMAL:0000802 def: "The process by which a microorganism (or other particulate material) is rendered more susceptible to phagocytosis by coating with an opsonin, a blood serum protein such as a complement component or antibody." [GO:0008228] is_a: IDOMAL:0000561 ! host immune effector process created_by: guest creation_date: 2009-11-30T04:47:52Z [Term] id: GO:0009987 name: cellular process alt_id: IDOMAL:0000809 def: "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GO:0009987] synonym: "cell physiology" EXACT [] synonym: "cellular physiological process" EXACT [] is_a: IDOMAL:0001054 ! process of malaria host created_by: guest creation_date: 2009-12-08T09:39:44Z [Term] id: GO:0019882 name: antigen processing and presentation alt_id: IDOMAL:0000803 def: "The process by which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GO:0019882] synonym: "antigen presentation" EXACT [] synonym: "antigen processing" EXACT [] is_a: IDOMAL:0000005 ! host immune system process created_by: guest creation_date: 2009-12-08T11:26:39Z [Term] id: GO:0019883 name: antigen processing and presentation of endogenous antigen alt_id: IDOMAL:0000829 def: "The process by which an antigen-presenting cell expresses antigen (peptide or lipid) of endogenous origin on its cell surface in association with an MHC protein complex." [GO:0019883] synonym: "antigen presentation, endogenous antigen" EXACT [] is_a: GO:0019882 ! antigen processing and presentation created_by: guest creation_date: 2009-12-08T11:42:21Z [Term] id: GO:0019884 name: antigen processing and presentation of exogenous antigen alt_id: IDOMAL:0000830 def: "The process by which an antigen-presenting cell expresses antigen (peptide or lipid) of exogenous origin on its cell surface in association with an MHC protein complex." [GO:0019884] synonym: "antigen presentation, exogenous antigen" EXACT [] is_a: GO:0019882 ! antigen processing and presentation created_by: guest creation_date: 2009-12-08T11:42:21Z [Term] id: GO:0020013 name: rosetting alt_id: IDOMAL:0000705 def: "The binding of parasite infected erythrocytes to uninfected erythrocytes." [GO:0020013] synonym: "rosette formation" BROAD [] is_a: IDOMAL:0000072 ! pathogen-host interaction relationship: part_of IDOMAL:0000095 ! evasion of host immune response created_by: guest creation_date: 2009-11-25T02:18:56Z [Term] id: GO:0030100 name: regulation of endocytosis alt_id: IDOMAL:0000111 def: "Any process that modulates the frequency, rate or extent of endocytosis." [GO:0030100] is_a: GO:0065007 ! biological regulation created_by: Ioana creation_date: 2009-12-17T10:39:30Z [Term] id: GO:0033000 name: Fc-gamma receptor I complex alt_id: IDOMAL:0000046 def: "A protein complex composed of an Fc-gamma RI alpha chain and an Fc-epsilon RI gamma chain dimer with or without additional signaling components. The complex functions primarily as an activating receptor for IgG." [GO:0033000] synonym: "FcgRI complex" EXACT [] synonym: "IgG receptor complex" BROAD [] synonym: "immunoglobulin G receptor complex" BROAD [] is_a: IDOMAL:0000048 ! Fc receptor complex relationship: has_role IDOMAL:0000373 ! receptor relationship: participates_in IDOMAL:0000123 ! Fc-gamma receptor I recognition created_by: Ioana creation_date: 2009-12-16T05:22:05Z [Term] id: GO:0043299 name: leukocyte degranulation alt_id: IDOMAL:0000039 def: "The regulated exocytosis of secretory granules by a leukocyte." [GO:0043299] synonym: "immune cell degranulation" EXACT [] synonym: "immune cell granule exocytosis" EXACT [] synonym: "leucocyte degranulation" EXACT [] synonym: "leukocyte granule exocytosis" EXACT [] is_a: IDOMAL:0000561 ! host immune effector process created_by: Ioana creation_date: 2009-12-16T05:13:14Z [Term] id: GO:0043320 name: natural killer cell degranulation alt_id: IDOMAL:0000394 def: "The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a natural killer cell." [GO:0043320] synonym: "natural killer cell granule exocytosis" EXACT [] synonym: "NK cell degranulation" EXACT [] synonym: "NK cell granule exocytosis" EXACT [] synonym: "NK-cell degranulation" EXACT [] synonym: "NK-cell granule exocytosis" EXACT [] is_a: GO:0043299 ! leukocyte degranulation relationship: part_of IDOMAL:0000392 ! natural killer cell mediated cytotoxic response created_by: guest creation_date: 2009-11-22T07:54:25Z [Term] id: GO:0045087 name: innate immune response alt_id: IDOMAL:0000007 def: "Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens." [GO:0045087] is_a: IDOMAL:0000006 ! host immune response created_by: guest creation_date: 2009-11-20T01:54:15Z [Term] id: GO:0045728 name: respiratory burst after phagocytosis alt_id: IDOMAL:0000806 def: "A phase of elevated metabolic activity, during which oxygen consumption increases, that occurs in neutrophils, monocytes, and macrophages shortly after phagocytosing material. An enhanced uptake of oxygen leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, which play a part in microbiocidal activity." [GO:0045728] synonym: "metabolic burst after phagocytosis" EXACT [] synonym: "oxidative burst after phagocytosis" EXACT [] is_a: GO:0002679 ! respiratory burst during defense response relationship: part_of IDOMAL:0000150 ! lysosome independent killing created_by: guest creation_date: 2009-11-30T06:03:42Z [Term] id: GO:0046209 name: nitric oxide metabolic process alt_id: IDOMAL:0000159 def: "The chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water." [GO:0046209] synonym: "nitric oxide metabolism" EXACT [] is_a: GO:0006807 ! nitrogen compound metabolic process created_by: guest creation_date: 2009-11-20T06:59:48Z [Term] id: GO:0048511 name: rythmic process alt_id: IDOMAL:0002030 def: "Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism." [GO:0048511] is_a: IDOMAL:0002137 ! behavioural process created_by: Pantelis creation_date: 2009-07-14T10:59:02Z [Term] id: GO:0050765 name: negative regulation of phagocytosis alt_id: IDOMAL:0000112 def: "Any process that stops, prevents or reduces the frequency, rate or extent of phagocytosis." [GO:0050765] synonym: "down regulation of phagocytosis" EXACT [] synonym: "down-regulation of phagocytosis" EXACT [] synonym: "downregulation of phagocytosis" EXACT [] is_a: GO:0030100 ! regulation of endocytosis created_by: Ioana creation_date: 2009-12-17T10:42:31Z [Term] id: GO:0050896 name: response to stimulus alt_id: IDOMAL:0002306 def: "A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." [GO:0050896] synonym: "physiological response to stimulus" EXACT [] is_a: IDOMAL:0002112 ! physiological process of malaria vector created_by: elvira creation_date: 2007-11-23T01:23:00Z [Term] id: GO:0051704 name: multi-organism process alt_id: IDOMAL:0000014 def: "Any process by which an organism has an effect on another organism of the same or different species." [GO:0051704] synonym: "interaction between organisms" EXACT [] synonym: "physiological interaction between organisms" EXACT [] synonym: "physiological interaction with other organism" EXACT [] is_a: IDOMAL:0000000 ! process created_by: Ioana creation_date: 2009-12-16T04:07:50Z [Term] id: GO:0065007 name: biological regulation alt_id: IDOMAL:0000108 def: "Any process that modulates the frequency, rate or extent of any biological process, quality or function." [GO:0065007] synonym: "regulation" BROAD [] is_a: IDOMAL:0001054 ! process of malaria host created_by: Ioana creation_date: 2009-12-17T10:37:20Z [Term] id: IDOMAL:0000000 name: process def: "A processual entity that is a maximally connected spatio-temporal whole, and has bona fide beginnings and endings corresponding to real discontinuities." [BFO:SPAN "http://www.ifomis.org/bfo/manual p64"] [Term] id: IDOMAL:0000001 name: role def: "A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant entity in virtue of the kind of thing that it is, but that can be served or participated in by that kind of continuant entity in some kinds of natural, social or institutional contexts." [BFO:SNAP "http://www.ifomis.org/bfo/manual p56"] [Term] id: IDOMAL:0000002 name: quality def: "A dependent continuant that is exhibited if it inheres in an entity or entities at all (a categorical property)." [BFO:SNAP "http://www.ifomis.org/bfo/manual p53"] [Term] id: IDOMAL:0000003 name: object def: "A independent continuant entity that is spatially extended, maximally self-connected and self-contained (the parts of a substance are not separated from each other by spatial gaps), and possesses an internal unity; the identity of substantial objects is independent of that of other entities and can be maintained through time and through loss and gain of parts and qualities." [BFO:SNAP "http://www.ifomis.org/bfo/manual p48"] [Term] id: IDOMAL:0000004 name: virulence def: "A quality that inheres in an infectious agent and is the degree to which realizations of the infectious disease caused by the infectious agent become severe or fatal." [IDO:466] comment: The degree of pathogenicitynnpathogenicity and virulence are used in some communities as synonyms. is_a: IDOMAL:0000347 ! quality of pathogen [Term] id: IDOMAL:0000005 name: host immune system process def: "Any host process involved in the development or functioning of the immune system,an organismal system of calibrated responses to potential internal or invasive threats." [IB:IB] is_a: IDOMAL:0001054 ! process of malaria host created_by: guest creation_date: 2009-11-20T01:50:54Z [Term] id: IDOMAL:0000006 name: host immune response def: "Any host immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat." [IB:IB] is_a: IDOMAL:0000005 ! host immune system process created_by: guest creation_date: 2009-11-20T01:52:35Z [Term] id: IDOMAL:0000008 name: contagiousness def: "The ability to spread from one person or species to another." [PT:PT] is_a: IDOMAL:0000635 ! quality of malaria [Term] id: IDOMAL:0000009 name: latency def: "The ability of a pathogen to lie dormant." [PT:PT] comment: Infection has occurred, but it might not have manifested itselfnquality of being in a non replicative statentime to manifest itself na pathogen when it is in a non replicative state. is_a: IDOMAL:0000347 ! quality of pathogen [Term] id: IDOMAL:0000010 name: immunosuppression def: "The act that reduces the activation or efficacy of the immune system due to therapy with immunosuppressant drugs." [KL:KL] is_a: IDOMAL:0001054 ! process of malaria host relationship: realizes IDOMAL:0000024 ! immunodeficiency [Term] id: IDOMAL:0000011 name: exogenous def: "The pathogen is not normally present in the host body, but have gained entrance from the environment." [PT:PT] is_a: IDOMAL:0000347 ! quality of pathogen [Term] id: IDOMAL:0000012 name: immunity def: "The quality of being immune." [KL:KL] is_a: IDOMAL:0000346 ! quality of host [Term] id: IDOMAL:0000015 name: bulaquine def: "An 8-aminoquinoline antimalarial drug." [ISBN:978-3-540-48994 "Encyclopedia of Parasitology"] synonym: "elubaquine" EXACT [] is_a: IDOMAL:0000208 ! 8-aminoquinoline created_by: Ioana creation_date: 2009-12-16T04:14:51Z [Term] id: IDOMAL:0000016 name: CD36 def: "Is a integral membrane protein found on the surface of various cells. It is thought to have a hairpin-like structure with alpha-helices at the C- and N-termini projecting through the membrane and a larger extracellular loop." [Wikipedia:CD36] synonym: "cluster of differentiation 36" EXACT [] synonym: "FAT" EXACT [] synonym: "GP88" EXACT [] synonym: "SCARB3" EXACT [] synonym: "thrombospodin receptor" BROAD [] is_a: IDOMAL:0001233 ! human host protein relationship: has_role IDOMAL:0000035 ! scavenger receptor relationship: participates_in GO:0002281 ! macrophage activation during immune response relationship: participates_in GO:0020013 ! rosetting relationship: participates_in IDOMAL:0000107 ! CD36 recognition created_by: Ioana creation_date: 2009-12-16T04:19:38Z [Term] id: IDOMAL:0000017 name: mortality of malaria def: "Mortality rate is a measure of the number of deaths due to malaria in some population, scaled to the size of that population, per unit time." [KL:KL] is_a: IDOMAL:0000351 ! quality of host population [Term] id: IDOMAL:0000018 name: fiat process part of malaria host def: "The fiat process part occuring in a malaria host." [IB:IB] is_a: IDOMAL:0002223 ! fiat process part created_by: Ioana creation_date: 2009-12-16T04:38:22Z [Term] id: IDOMAL:0000019 name: prevalence of malaria def: "The number of malaria cases existing in a given population at any given time." [KL:KL] comment: Total number of cases of a particular disease at a given time in a particular population divided by the number of individuals in that particular population. The burden of a disease in a population. synonym: "point prevalence of malaria" RELATED [] is_a: IDOMAL:0000351 ! quality of host population [Term] id: IDOMAL:0000021 name: malaria vaccination def: "The administration of antigenic material from malaria pathogen to produce immunity to malaria." [PT:PT] is_a: IDOMAL:0001040 ! vaccination created_by: Pantelis creation_date: 2010-02-22T09:42:30Z [Term] id: IDOMAL:0000022 name: cell mediated immune response def: "An immune response involving a change in the state or activity of a cell in response to stimulus." [IB:IB] is_a: IDOMAL:0000561 ! host immune effector process created_by: guest creation_date: 2009-11-20T02:35:08Z [Term] id: IDOMAL:0000023 name: zoonotic def: "A disease that can be transmitted from animals to people." [MedicineNET.com:zoonotic] is_a: IDOMAL:0000635 ! quality of malaria [Term] id: IDOMAL:0000024 name: immunodeficiency def: "The condition of a vertebrate host unable to develop a normal immune response usually because of malnutrition or immunosuppressive therapy or disease or other reasons." [KL:KL] is_a: IDOMAL:0000346 ! quality of host relationship: part_of IDOMAL:0000012 ! immunity [Term] id: IDOMAL:0000025 name: pathogenicity def: "Pathogenicity is the ability of an organism, a pathogen, to produce an infectious disease in another organism." [Wikipedia:pathogenicity] comment: The ability of the biotic entity to cause disease in a host of a given type.\nDo we need to say damage instead of disease?\nPathogenicity and virulence are used as synonyms in some communities. is_a: IDOMAL:0000347 ! quality of pathogen [Term] id: IDOMAL:0000026 name: RTS,S/AS02(A) def: "RTS,S/AS02(A) is a pre-erythrocytic vaccine candidate based on Plasmodium falciparum circumsporozoite protein (CSP)." [IB:IB] is_a: IDOMAL:0000115 ! plasmodium falciparum vaccine created_by: Ioana creation_date: 2009-12-17T02:49:29Z [Term] id: IDOMAL:0000027 name: drug resistance def: "A protective resistance that mitigates the damaging effects of a drug." [IDO:445] is_a: IDOMAL:0000347 ! quality of pathogen [Term] id: IDOMAL:0000028 name: antibiotic resistance def: "The ability of a pathogen to display a reduction in effectiveness of an antibiotic drug, that intends to kill it." [PT:PT] is_a: IDOMAL:0000027 ! drug resistance [Term] id: IDOMAL:0000029 name: epidemiological type of malaria def: "The quality of forms of malaria that are different from the epidemiological point of view." [KL:KL] is_a: IDOMAL:0000635 ! quality of malaria [Term] id: IDOMAL:0000030 name: invasiveness def: "The ability to enter into a living body." [PT:PT] xref: ISBN:034057190X "Essential Malariology" is_a: IDOMAL:0000347 ! quality of pathogen [Term] id: IDOMAL:0000031 name: endogenous def: "The pathogen is normally present in the host body." [PT:PT] is_a: IDOMAL:0000347 ! quality of pathogen [Term] id: IDOMAL:0000032 name: toll like receptor 2 def: "A toll-like receptor that is a translation product of the TLR2 gene." [PRO:000001153] synonym: "TLR2" EXACT [] is_a: IDOMAL:0001233 ! human host protein relationship: has_role IDOMAL:0000370 ! toll like receptor relationship: participates_in GO:0002277 ! myeloid dendritic cell activation during immune response relationship: participates_in IDOMAL:0000785 ! toll like receptor 2 recognition created_by: Ioana creation_date: 2009-12-16T04:46:40Z [Term] id: IDOMAL:0000033 name: morbidity of malaria def: "The term morbidity refers to either the incidence rate, or the prevalence of malaria. This measure of sickness is contrasted with the mortality rate, which is the proportion of people dying during a given time interval." [KL:KL] is_a: IDOMAL:0000351 ! quality of host population [Term] id: IDOMAL:0000034 name: toll like receptor 9 def: "A toll-like receptor that is a translation product of the TLR9 gene." [PRO:000001160] synonym: "TLR9" EXACT [] is_a: IDOMAL:0001233 ! human host protein relationship: has_role IDOMAL:0000370 ! toll like receptor relationship: participates_in GO:0002271 ! plasmacytoid dendritic cell activation during immune response relationship: participates_in IDOMAL:0000652 ! toll like receptor 9 recognition created_by: Ioana creation_date: 2009-12-16T04:51:41Z [Term] id: IDOMAL:0000035 name: scavenger receptor def: "Scavenger receptors recognize modified low-density lipoprotein (LDL) by oxidation or acetylation, as well as other various ligands." [IB:IB] is_a: IDOMAL:0000373 ! receptor created_by: Ioana creation_date: 2009-12-16T05:04:29Z [Term] id: IDOMAL:0000036 name: FMP1/AS02(A ) def: "FMP2.1/AS02(A) is a recombinant E. coli-expressed protein based upon the apical membrane antigen-1 (AMA-1) of the 3D7 clone formulated with the AS02A adjuvant." [VO:0000777] xref: VO:0000777 is_a: IDOMAL:0000115 ! plasmodium falciparum vaccine created_by: Ioana creation_date: 2009-12-17T02:52:59Z [Term] id: IDOMAL:0000038 name: antiparasitic humoral response def: "An immune response against parasites mediated through a body fluid. One example of antiparasitic humoral response is the secretion of antiparasitic antibodies produced by the cells of the B lymphocyte lineage." [IB:IB] is_a: IDOMAL:0000808 ! humoral immune response relationship: part_of IDOMAL:0000748 ! B cell mediated immune response created_by: guest creation_date: 2009-11-20T02:40:24Z [Term] id: IDOMAL:0000040 name: virulence factor def: "A virulence factor is a molecule produced by a pathogen that specifically causes disease, or that influences the host's function to allow the pathogen to thrive." [KL:KL] comment: Role played by a portion of substance to promote virulencennmagnitudendegree of pathogenesis. is_a: IDOMAL:0000341 ! factor [Term] id: IDOMAL:0000041 name: gamma-delta T cell receptor complex def: "The gamma-delta T cell receptor is a heterodimer consisting of one gamma and one delta chain." [Wikipedia:gamma-deltaTcells] synonym: "gamma-delta T-cell receptor complex" EXACT [] is_a: IDOMAL:0000732 ! protein complex relationship: has_role IDOMAL:0000373 ! receptor created_by: Ioana creation_date: 2009-12-16T05:18:49Z [Term] id: IDOMAL:0000042 name: invasin def: "An enzyme that degrades hyaluronic acid, found in lysosomes." [KL:KL] synonym: "hyaluronidase 1" EXACT [] is_a: IDOMAL:0000040 ! virulence factor [Term] id: IDOMAL:0000043 name: toxin def: "A toxin is a poisonous substance produced by living cells or organisms." [Wikipedia:toxin] is_a: IDOMAL:0000040 ! virulence factor [Term] id: IDOMAL:0000044 name: endotoxin def: "A toxin that is associated with certain bacteria. Classically, an \"endotoxin\" is a toxin that, unlike an \"exotoxin\", is not secreted in soluble form by live bacteria, but is a structural component in the bacteria which is released mainly when bacteria are lysed." [KL:KL] is_a: IDOMAL:0000043 ! toxin [Term] id: IDOMAL:0000045 name: exotoxin def: "An exotoxin is a toxin excreted by a microrganism, including bacteria, fungi, algae, and protozoa." [Wikipedia:exotoxin] is_a: IDOMAL:0000043 ! toxin [Term] id: IDOMAL:0000047 name: treatment of malaria def: "The therapeutic process for malaria." [KL:KL] is_a: IDOMAL:0000959 ! process of malaria [Term] id: IDOMAL:0000048 name: Fc receptor complex def: "A protein complex composed of a subunit or subunits capable of binding the Fc portion of an immunoglobulin with additional signaling components." [IB:IB] synonym: "Fc-receptor complex" EXACT [] synonym: "FcR complex" EXACT [] synonym: "immunoglobulin receptor complex" BROAD [] is_a: IDOMAL:0000732 ! protein complex relationship: participates_in IDOMAL:0000078 ! antibody-dependent cell-mediated cytotoxic response created_by: Ioana creation_date: 2009-12-16T05:32:57Z [Term] id: IDOMAL:0000049 name: diagnostic procedure of malaria def: "A procedure used for the diagnosis of malaria, including the precise pathogen causing the disease." [KL:KL] synonym: "diagnostic procedure of infectious disease" RELATED [] is_a: IDOMAL:0000959 ! process of malaria created_by: louis creation_date: 2008-05-13T08:10:31Z [Term] id: IDOMAL:0000050 name: chemotherapy of malaria def: "The use of antimalarial drugs to kill Plasmodium parasites and, therefore, cure malaria." [KL:KL] is_a: IDOMAL:0000959 ! process of malaria relationship: part_of IDOMAL:0000047 ! treatment of malaria relationship: part_of IDOMAL:0000325 ! attack phase of malaria eradication [Term] id: IDOMAL:0000051 name: ancillary treatment of malaria def: "Therapeutic measures taken, in addition to chemotherapy, to improve the condition of, and cure a malaria patient." [KL:KL] is_a: IDOMAL:0000959 ! process of malaria relationship: part_of IDOMAL:0000047 ! treatment of malaria [Term] id: IDOMAL:0000052 name: arylaminoalcohol def: "A class of alkaloids originally extracted from the bark of the Cinchona tree. Usually used for the treatment of acute infection (schizontocidal effect), with mefloquine also used for prophylaxis." [KL:KL] is_a: IDOMAL:0000672 ! chemical compound relationship: has_role IDOMAL:0000258 ! malaria treatment drug created_by: louis creation_date: 2008-01-24T03:18:00Z [Term] id: IDOMAL:0000053 name: colonization factor def: "A factor mediating colonization." [KL:KL] comment: Role played by portion of physical substance which promotes colonization. synonym: "" RELATED [] is_a: IDOMAL:0000341 ! factor [Term] id: IDOMAL:0000054 name: adhesion factor def: "A factor mediating cell-cell or cell-tissue adhesion." [KL:KL] comment: Role played by portion of physical substance utilized by an organism in order to establish adherence to a surface in a host. synonym: "adhesin" RELATED [] synonym: "adhesin factor" RELATED [] is_a: IDOMAL:0000341 ! factor [Term] id: IDOMAL:0000055 name: host def: "A role borne by an organism by virtue of the fact it provides an environment supportive for the survival or reproduction of an entity of another type." [IDO:408] is_a: IDOMAL:0000001 ! role [Term] id: IDOMAL:0000056 name: carrier def: "A person or other organism that has contracted an infectious disease, but who displays no symptoms. Although unaffected by the disease themselves, carriers can transmit it to others." [Wikipedia:Asymptomaticcarrier "http://en.wikipedia.org/wiki/Asymptomatic_carrier"] synonym: "Asymptomatic carrier" EXACT [] is_a: IDOMAL:0000055 ! host [Term] id: IDOMAL:0000057 name: chronic carrier def: "A carrier who harbors and transmits an infectious agent for an indefinite period." [PT:PT] is_a: IDOMAL:0000056 ! carrier [Term] id: IDOMAL:0000058 name: reservoir def: "A role borne by a material entity by virtue of the fact that it is a habitat in which an infectious agent is persisting and multiplying and from which the infectious agent can be transmitted." [IDO:424] comment: Holding place for a potential pathogen. Animate or inanimate. is_a: IDOMAL:0000001 ! role [Term] id: IDOMAL:0000059 name: antimalarial drug combination def: "Combinations of two or more blood schizonticidal drugs, simultaneously used, with independent modes of action and different biochemical targets in the parasite." [KL:KL] is_a: IDOMAL:0000611 ! object aggregate created_by: louis creation_date: 2010-03-31T08:15:00Z [Term] id: IDOMAL:0000061 name: conventional dendritic cell activation during immune response def: "A change in the morphology and behaviour of a conventional dendritic cell resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [IB:IB] synonym: "conventional DC activation during immune response" EXACT [] is_a: IDOMAL:0000295 ! dendritic cell activation during immune response created_by: Ioana creation_date: 2009-12-16T05:39:08Z [Term] id: IDOMAL:0000063 name: pathogen def: "A role borne by an object in virtue of the fact that it is sufficiently close to an organism towards which it has the pathogenic disposition to allow processes resulting in disorder to occur." [IDO:405] is_a: IDOMAL:0000001 ! role [Term] id: IDOMAL:0000064 name: B cell receptor complex def: "It is composed of membrane-bound immunoglobulin (mIg) and disulfide-linked heterodimers, Ig-alpha and Ig-beta. One mIg is associated with one heterodimer,containing immunoglobulin-fold structure and cytoplasmic tails. The cytoplasmic tails interact with intracellular signaling molecules." [Kuby:Immunology4e] synonym: "B lymphocyte receptor complex" EXACT [] synonym: "B-cell receptor complex" EXACT [] synonym: "B-lymphocyte receptor complex" EXACT [] synonym: "BCR" EXACT [] is_a: IDOMAL:0000732 ! protein complex relationship: has_role IDOMAL:0000373 ! receptor relationship: participates_in GO:0002312 ! B cell activation during immune response relationship: participates_in IDOMAL:0000621 ! B cell receptor recognition created_by: Ioana creation_date: 2009-12-16T05:44:14Z [Term] id: IDOMAL:0000065 name: alpha-beta T cell receptor complex def: "The alpha-beta T cell receptor is a heterodimer consisting of one alpha and one beta chain. It associates with CD3, composed of one gamma chain, one delta chain, and two epsilon chains. The alpha-beta T cell receptor, CD3 complex and two zeta chains together form the alpha-beta T cell receptor complex." [Wikipedia:Tcellreceptor] synonym: "T lymphocyte receptor complex" EXACT [] synonym: "T-cell receptor complex" EXACT [] synonym: "T-lymphocyte receptor complex" EXACT [] synonym: "TCR" EXACT [] is_a: IDOMAL:0000732 ! protein complex created_by: Ioana creation_date: 2009-12-16T05:48:52Z [Term] id: IDOMAL:0000066 name: secondary pathogen def: "An infectious microorganism, often a bacterium, that is normally a commensal or does not harm its host but can cause additional complications, especially during the course of severe malaria (e.g. pneumonia, etc.)." [KL:KL] is_a: IDOMAL:0000063 ! pathogen [Term] id: IDOMAL:0000067 name: CD4-positive, alpha-beta T cell receptor complex def: "CD4 is a monomeric membrane glycoprotein consisting off four extracellular immunoglobulin-like domains, one hydrophobic transmembrane region and one cytoplasmic tail. CD4 is a co-receptor and associates with the alpha-beta T cell receptor complex." [Kuby:Immunology43, Wikipedia:Tcellreceptor] synonym: "CD4-positive, alpha-beta T lymphocyte receptor complex" EXACT [] synonym: "CD4-positive, alpha-beta T-cell receptor complex" EXACT [] synonym: "CD4-positive, alpha-beta T-lymphocyte receptor complex" EXACT [] is_a: IDOMAL:0000065 ! alpha-beta T cell receptor complex relationship: has_role IDOMAL:0000373 ! receptor relationship: participates_in IDOMAL:0000641 ! CD4-positive, alpha-beta T cell receptor recognition created_by: Ioana creation_date: 2009-12-16T05:54:27Z [Term] id: IDOMAL:0000068 name: CD8-positive, alpha-beta T cell receptor complex def: "CD8 is either composed of disulfide-linked alpha and beta chain heterodimer or two alpha chain homodimer. Each chain consists of one immunoglobulin-like region, one hydrophobic transmembrane region and one cytoplasmic tail. CD8 is a co-receptor and associates with the alpha-beta T cell receptor complex." [Kuby:Immunology4e] synonym: "CD8-positive, alpha-beta T lymphocyte receptor complex" EXACT [] synonym: "CD8-positive, alpha-beta T-cell receptor complex" EXACT [] synonym: "CD8-positive, alpha-beta T-lymphocyte receptor complex" EXACT [] is_a: IDOMAL:0000065 ! alpha-beta T cell receptor complex relationship: has_role IDOMAL:0000373 ! receptor relationship: participates_in IDOMAL:0000470 ! CD8-positive, alpha-beta cytotoxic T cell activation during immune response relationship: participates_in IDOMAL:0000642 ! CD8-positive, alpha-beta T cell receptor recognition created_by: Ioana creation_date: 2009-12-16T05:54:27Z [Term] id: IDOMAL:0000069 name: gamma-delta T cell mediated immune response def: "An immune response involving a change in the state or activity of a gamma-delta T cell in response to stimulus." [IB:IB] synonym: "gamma-delta T lymphocyte mediated immune response" EXACT [] synonym: "gamma-delta T-cell mediated immune response" EXACT [] synonym: "gamma-delta T-lymphocyte mediated immune response" EXACT [] is_a: IDOMAL:0000747 ! T cell mediated immune response created_by: guest creation_date: 2009-11-20T03:04:40Z [Term] id: IDOMAL:0000070 name: initiation of infection def: "The beginning of malaria through the introduction of Plasmodium into the body of an individual." [KL:KL] relationship: part_of IDOMAL:0000091 ! progression of malaria [Term] id: IDOMAL:0000071 name: disruption of body surface def: "The disruption of the body surface in malaria transmission, either through a mosquito bite or in a case of iatrogenic transmission." [KL:KL] is_a: IDOMAL:0000070 ! initiation of infection [Term] id: IDOMAL:0000072 name: pathogen-host interaction def: "Any process that includes interactions between a parasite and its host." [KL:KL] is_a: GO:0051704 ! multi-organism process created_by: Ioana creation_date: 2009-12-16T06:20:30Z [Term] id: IDOMAL:0000073 name: Plasmodium adherence to host cell comment: Create cross products for "host" and "pathogen" that will be part of this process. is_obsolete: true [Term] id: IDOMAL:0000074 name: nonspecific adherence is_obsolete: true [Term] id: IDOMAL:0000075 name: specific adherence is_obsolete: true [Term] id: IDOMAL:0000076 name: bacterium def: "A unicellular prokaryotic microorganism." [KL:KL] is_a: IDOMAL:0000343 ! biotic created_by: louis creation_date: 2009-06-30T02:46:36Z [Term] id: IDOMAL:0000077 name: fungus def: "A fungus is an eukaryotic organism that is a member of the kingdom Fungi." [KL:KL] is_a: IDOMAL:0000343 ! biotic created_by: louis creation_date: 2009-06-30T02:46:36Z [Term] id: IDOMAL:0000078 name: antibody-dependent cell-mediated cytotoxic response def: "Cytolysis of target cells through release of cytokines by natural killer cells, eosinophils, neutrophils, monocytes, T cells or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells." [IB:IB] synonym: "ADCC" EXACT [] is_a: IDOMAL:0000776 ! leukocyte mediated cytotoxic response relationship: part_of IDOMAL:0000038 ! antiparasitic humoral response created_by: guest creation_date: 2009-11-20T03:04:40Z [Term] id: IDOMAL:0000079 name: phagocytosis, recognition def: "The initial step in phagocytosis involving adhesion to parasite and other particulate matter, based on recognition of factors such as parasitical components, opsonins like complement and antibody or protein receptors, leading to intracellular signaling in the phagocytosing cell." [IB:IB] is_a: GO:0008037 ! cell recognition created_by: guest creation_date: 2009-11-20T03:11:58Z [Term] id: IDOMAL:0000080 name: pathogen-vector interaction def: "Any process that includes interactions between a parasite and its vector." [KL:KL] is_a: GO:0051704 ! multi-organism process created_by: Ioana creation_date: 2009-12-16T06:20:30Z [Term] id: IDOMAL:0000081 name: phagocytosis, killing of parasite def: "Processes during phagocytosis, resulting in the killing of the ingested parasite, and/or parasite components." [IB:IB] relationship: part_of IDOMAL:0000117 ! phagocytosis during adaptive immune response relationship: part_of IDOMAL:0000124 ! phagocytosis during innate immune response created_by: guest creation_date: 2009-11-20T03:11:58Z [Term] id: IDOMAL:0000082 name: malaria transmission def: "The process by which an infectious agent passes from one organism to another organism." [Wikipedia:Transmission] is_a: IDOMAL:0000959 ! process of malaria relationship: part_of IDOMAL:0001053 ! occurrence of malaria [Term] id: IDOMAL:0000083 name: complement receptor recognition def: "The process by which a complement receptor in the malaria host interprets its surroundings." [IB:IB] is_a: IDOMAL:0000697 ! receptor recognition relationship: part_of IDOMAL:0000079 ! phagocytosis, recognition relationship: part_of IDOMAL:0000124 ! phagocytosis during innate immune response created_by: guest creation_date: 2009-11-20T03:15:49Z [Term] id: IDOMAL:0000084 name: Plasmodium penetration of host cell def: "The process of entry of a Plasmodium parasite into a host cell." [KL:KL] is_a: GO:0051704 ! multi-organism process is_a: IDOMAL:0001058 ! process of malaria pathogen [Term] id: IDOMAL:0000085 name: engulfment def: "The enclosure of a foreign body or cell by a cellular component of the immune system." [KL:KL] is_obsolete: true [Term] id: IDOMAL:0000086 name: fusion with invertebrate host cell membrane def: "The first steps in the process of the penetration of the host cell during which a Plasmodium organism fuses with the membrane of an invertebrate host's cell." [KL:KL] is_a: IDOMAL:0000080 ! pathogen-vector interaction relationship: part_of IDOMAL:0001004 ! Plasmodium penetration of invertebrate host [Term] id: IDOMAL:0000087 name: membrane invagination is_obsolete: true [Term] id: IDOMAL:0000088 name: passage through invertebrate host cell membrane def: "The process of a Plasmodium organism penetrating and passing through an invertebrate host cell membrane." [KL:KL] is_a: IDOMAL:0000080 ! pathogen-vector interaction relationship: part_of IDOMAL:0001004 ! Plasmodium penetration of invertebrate host [Term] id: IDOMAL:0000089 name: engulfment by nonphagocyte def: "The engulfment of a foreign body or cell by a cell other than a phagocyte." [KL:KL] is_obsolete: true [Term] id: IDOMAL:0000090 name: engulfment by phagocyte def: "The engulfment of a foreign body or cell by a phagocyte." [KL:KL] is_obsolete: true [Term] id: IDOMAL:0000091 name: progression of malaria def: "All clinical features of malaria from infection to cure or death." [KL:KL] relationship: part_of IDOMAL:0001053 ! occurrence of malaria created_by: louis creation_date: 2008-09-09T12:17:40Z [Term] id: IDOMAL:0000092 name: temporal region def: "An occurrent [span:Occurrent] that is part of time." [SPAN:temporal region "http://www.ifomis.org/bfo/1.1/span#TemporalRegion"] created_by: louis creation_date: 2009-06-30T01:14:07Z [Term] id: IDOMAL:0000093 name: condition of malaria host def: "A condition mostly relating to the human host." [KL:KL] is_a: IDOMAL:0001241 ! condition created_by: louis creation_date: 2009-06-30T02:15:22Z [Term] id: IDOMAL:0000094 name: evasion of vector immune response def: "The ability of a pathogen to evade the immune response of the vector." [KL:KL] is_a: IDOMAL:0000099 ! Plasmodium evasion of immune response created_by: louis creation_date: 2008-09-09T12:40:36Z [Term] id: IDOMAL:0000095 name: evasion of host immune response def: "The ability of a pathogen to evade the immune response of the host." [KL:KL] is_a: IDOMAL:0000099 ! Plasmodium evasion of immune response created_by: louis creation_date: 2008-09-09T12:41:17Z [Term] id: IDOMAL:0000096 name: Plasmodium spread through host def: "Any process linked to Plasmodium multiplying in a host." [KL:KL] is_a: IDOMAL:0001058 ! process of malaria pathogen [Term] id: IDOMAL:0000097 name: scavenger receptor recognition def: "The process by which a scavenger receptor in the malaria host interprets its surroundings." [IB:IB] is_a: IDOMAL:0000697 ! receptor recognition relationship: part_of IDOMAL:0000079 ! phagocytosis, recognition relationship: part_of IDOMAL:0000124 ! phagocytosis during innate immune response created_by: guest creation_date: 2009-11-20T03:15:49Z [Term] id: IDOMAL:0000098 name: Fc receptor recognition def: "The process by which a Fc receptor in the malaria host interprets its surroundings." [IB:IB] synonym: "FcR recognition" EXACT [] is_a: IDOMAL:0000697 ! receptor recognition relationship: part_of IDOMAL:0000079 ! phagocytosis, recognition relationship: part_of IDOMAL:0000117 ! phagocytosis during adaptive immune response created_by: guest creation_date: 2009-11-20T03:15:49Z [Term] id: IDOMAL:0000099 name: Plasmodium evasion of immune response def: "Any process, either passive or active, by which Plasmodium avoids the effects of the host or vector immune response." [IB:IB] is_a: IDOMAL:0001058 ! process of malaria pathogen [Term] id: IDOMAL:0000100 name: emergence of malaria def: "The appearance of more than one case of malaria in an area from which, at that time, the disease is absent." [KL:KL] comment: The process by which an infectious disease establishes itself in a new population (or at a sufficiently higher rate? Higher prevalence and/or higher incidence). is_a: IDOMAL:0001037 ! process of malaria epidemiology relationship: part_of IDOMAL:0000101 ! spread of malaria [Term] id: IDOMAL:0000101 name: spread of malaria def: "The process through which malaria spreads from one initial patient to one or more individuals." [KL:KL] is_a: IDOMAL:0001037 ! process of malaria epidemiology [Term] id: IDOMAL:0000102 name: outbreak def: "Outbreak is a classification used in epidemiology to describe a small, localized group of people or organisms infected with a disease." [KL:KL] is_a: IDOMAL:0001037 ! process of malaria epidemiology relationship: part_of IDOMAL:0000101 ! spread of malaria [Term] id: IDOMAL:0000103 name: condition of malaria parasite def: "A condition relating to any species of Plasmodium parasites causing malaria." [KL:KL] is_a: IDOMAL:0001241 ! condition created_by: louis creation_date: 2009-06-30T02:15:22Z [Term] id: IDOMAL:0000104 name: complement receptor 1 recognition def: "The process by which a complement receptor 1 in the malaria host interprets its surroundings." [IB:IB] synonym: "CR1 recognition" EXACT [] is_a: IDOMAL:0000083 ! complement receptor recognition created_by: guest creation_date: 2009-11-20T03:16:05Z [Term] id: IDOMAL:0000105 name: immunization of population def: "A process that increases a populations reaction to malaria." [KL:KL] is_a: IDOMAL:0000954 ! process of malaria host population [Term] id: IDOMAL:0000106 name: vector-host interaction def: "Any process that includes interactions between a pathogen host and the pathogen's vector." [KL:KL] is_a: GO:0051704 ! multi-organism process created_by: Ioana creation_date: 2009-12-16T06:20:30Z [Term] id: IDOMAL:0000107 name: CD36 recognition def: "The process by which CD36 in the malaria host interprets its surroundings." [IB:IB] is_a: IDOMAL:0000121 ! scavenger receptor class B recognition created_by: guest creation_date: 2009-11-20T03:19:44Z [Term] id: IDOMAL:0000109 name: Plasmodium life cycle def: "The course of developmental changes through which an Plasmodium organism passes from its inception as a fertilized zygote to the stages that can produce another zygote. ." [KL:KL] is_a: IDOMAL:0001058 ! process of malaria pathogen created_by: louis creation_date: 2008-01-21T01:55:00Z [Term] id: IDOMAL:0000110 name: antigenic variation def: "Antigenic variation is the process by which an infectious organism alters its surface proteins in order to evade a host immune response." [Wikipedia:antigenicvariation] synonym: "Ag variation" EXACT [] is_a: IDOMAL:0001058 ! process of malaria pathogen relationship: part_of IDOMAL:0000095 ! evasion of host immune response [Term] id: IDOMAL:0000113 name: phase variation def: "The process of Plasmodium that leads to alteingr the antigens on the outer surface." [KL:KL] is_a: IDOMAL:0000110 ! antigenic variation [Term] id: IDOMAL:0000114 name: genetic variability def: "Genetic variability is a measure of the tendency of individual genotypes in a population to vary from one another." [Wikipedia:geneticvariability] synonym: "genetic diversification" NARROW [] is_a: IDOMAL:0000110 ! antigenic variation [Term] id: IDOMAL:0000115 name: plasmodium falciparum vaccine def: "A malaria vaccine that protects against malaria caused by Plasmodium falciparum." [VO:0000087] xref: VO:0000087 is_a: IDOMAL:0001055 ! malaria vaccine created_by: Ioana creation_date: 2009-12-17T02:27:23Z [Term] id: IDOMAL:0000116 name: epidemic malaria def: "Spread of malaria across a population beyond what is characterized as endemic." [KL:KL] is_a: IDOMAL:0001037 ! process of malaria epidemiology relationship: part_of IDOMAL:0000101 ! spread of malaria [Term] id: IDOMAL:0000117 name: phagocytosis during adaptive immune response def: "The process of phagocytosis during an adaptive immune response." [IB:IB] is_a: GO:0006909 ! phagocytosis relationship: part_of GO:0002250 ! adaptive immune response created_by: Ioana creation_date: 2009-12-17T11:04:39Z [Term] id: IDOMAL:0000118 name: vaccination of population def: "The administration of antigenic material (the vaccine) to members of a population to produce immunity to a disease in that population." [KL:KL] is_a: IDOMAL:0000105 ! immunization of population relationship: part_of IDOMAL:0000119 ! malaria prevention in individuals [Term] id: IDOMAL:0000119 name: malaria prevention in individuals alt_id: IDOMAL:0001226 def: "Malaria prevention includes all methods used by a person to avoid from contracting malaria. This is of importance both for inhabitants of a malaria-endemic area and visitors to that area." [KL:KL] comment: MERGED DEFINITION:TARGET DEFINITION: Malaria prevention includes all methods used by a person to avoid from contracting malaria. This is of importance both for inhabitants of a malaria-endemic area and visitors to that area.\nSOURCE DEFINITION: Administration of antimalarial drugs with the purpose of preventing infection. synonym: "chemoprophylaxis of malaria" RELATED [] relationship: part_of IDOMAL:0000158 ! malaria control created_by: louis creation_date: 2008-01-24T10:00:00Z [Term] id: IDOMAL:0000120 name: protozoon def: "A one-celled eukaryote. That implies that protozoa are unicellular microbes whose cells have membrane-bound nuclei that commonly show characteristics usually associated with animals -- mobility and heterotrophy." [Wikipedia:protozoa] is_a: IDOMAL:0000343 ! biotic created_by: louis creation_date: 2007-12-14T08:11:00Z [Term] id: IDOMAL:0000121 name: scavenger receptor class B recognition def: "The process by which a scavenger receptor class B in the malaria host interprets its surroundings." [IB:IB] is_a: IDOMAL:0000097 ! scavenger receptor recognition created_by: guest creation_date: 2009-11-20T03:26:02Z [Term] id: IDOMAL:0000122 name: chemoprophylaxis def: "The use of antimalarial drugs for the prevention of infection." [KL:KL] relationship: part_of IDOMAL:0000119 ! malaria prevention in individuals created_by: louis creation_date: 2008-01-24T10:04:00Z [Term] id: IDOMAL:0000123 name: Fc-gamma receptor I recognition def: "The process by which a Fc-gamma receptor I in the malaria host interprets its surroundings." [IB:IB] is_a: IDOMAL:0000098 ! Fc receptor recognition created_by: guest creation_date: 2009-11-20T03:42:54Z [Term] id: IDOMAL:0000124 name: phagocytosis during innate immune response def: "The process of phagocytosis during an innate immune response." [IB:IB] is_a: GO:0006909 ! phagocytosis relationship: part_of GO:0045087 ! innate immune response created_by: Ioana creation_date: 2009-12-17T11:06:55Z [Term] id: IDOMAL:0000125 name: apicomplexa def: "The Apicomplexa are a large group of protists, characterized by the presence of a unique organelle called an apical complex. They are unicellular, spore-forming, and exclusively parasites of animals. Motile structures such as flagella or pseudopods are absent except in certain gamete stages." [Wikipedia:apicomplexa] is_a: IDOMAL:0000120 ! protozoon created_by: louis creation_date: 2007-12-14T11:16:00Z [Term] id: IDOMAL:0000126 name: Plasmodium def: "Plasmodium is a genus of parasitic protozoa (Phylum: Apicomplexa; Class: Aconoidasida; Order: Haemosporida; Family: Plasmodiidae). Infection with this genus is called malaria." [KL:KL] synonym: "Malaria parasite" NARROW [] is_a: IDOMAL:0000125 ! apicomplexa created_by: louis creation_date: 2007-12-14T11:19:00Z [Term] id: IDOMAL:0000127 name: subgenus Plasmodium def: "A subgenus containing all species infecting monkeys and higher primates with the exception of P. falciparum and P. reichenowi." [KL:KL] is_a: IDOMAL:0000126 ! Plasmodium created_by: louis creation_date: 2007-12-14T11:28:00Z [Term] id: IDOMAL:0000128 name: Laverania def: "A subgenus containing P. falciparum and P. reichenowi, species infecting monkeys and higher primates." [ido:1] is_a: IDOMAL:0000126 ! Plasmodium created_by: louis creation_date: 2007-12-14T11:32:00Z [Term] id: IDOMAL:0000129 name: Plasmodium falciparum def: "A human parasite causing the malignant form of tertian (pernicious or malignant ) malaria, found in all continents." [KL:KL] is_a: IDOMAL:0000128 ! Laverania relationship: has_role IDOMAL:0001065 ! human malaria parasite created_by: louis creation_date: 2007-12-14T11:34:00Z [Term] id: IDOMAL:0000130 name: Plasmodium reichenowi def: "An African Chimpanzee parasite." [KL:KL] is_a: IDOMAL:0000128 ! Laverania relationship: has_role IDOMAL:0001269 ! monkey malaria parasite created_by: louis creation_date: 2007-12-14T11:36:00Z [Term] id: IDOMAL:0000131 name: Plasmodium ovale def: "A human parasite causing the less frequent form of benign (ovale) tertian malaria. P. ovale may also infect chimpanzees." [KL:KL] is_a: IDOMAL:0000127 ! subgenus Plasmodium relationship: has_role IDOMAL:0001065 ! human malaria parasite created_by: louis creation_date: 2007-12-14T11:40:00Z [Term] id: IDOMAL:0000132 name: Plasmodium vivax def: "A human parasite causing the most frequent form of benign (simple) tertian malaria. P. viax may also infect chimpanzees and orangutans." [KL:KL] is_a: IDOMAL:0000127 ! subgenus Plasmodium relationship: has_role IDOMAL:0001065 ! human malaria parasite created_by: louis creation_date: 2007-12-14T11:42:00Z [Term] id: IDOMAL:0000133 name: Plasmodium malariae def: "A human parasite causing quartan malaria." [KL:KL] is_a: IDOMAL:0000127 ! subgenus Plasmodium relationship: has_role IDOMAL:0001065 ! human malaria parasite created_by: louis creation_date: 2007-12-14T11:43:00Z [Term] id: IDOMAL:0000134 name: non-immune indigenous population def: "The non-immune population, excluding immigrants." [KL:KL] relationship: part_of IDOMAL:0000685 ! human population of non-immune individuals created_by: louis creation_date: 2008-01-24T10:45:00Z [Term] id: IDOMAL:0000135 name: P. falciparum vaccine Combination B def: "A malaria vaccine that comprises recombinant Plasmodium falciparum (P. falciparum) blood-stage proteins MSP1, MSP2 and RESA, formulated with the adjuvant Montanide ISA 720." [VO:0000740] xref: VO:0000740 is_a: IDOMAL:0000115 ! plasmodium falciparum vaccine created_by: Ioana creation_date: 2009-12-17T02:55:59Z [Term] id: IDOMAL:0000136 name: vaccine adjuvant def: "Substances used in vaccines to enhance the ability of antigens to elicit an immune response." [NCI Thesaurus:Vaccine_Adjuvant] is_a: IDOMAL:0000001 ! role relationship: part_of IDOMAL:0000262 ! vaccine created_by: Ioana creation_date: 2009-12-17T03:46:48Z [Term] id: IDOMAL:0000137 name: agglutination def: "Agglutination is the clumping of cells, parasites, or particles, which may or may not occur in the presence of antibodies." [IB:IB] is_a: GO:0009987 ! cellular process relationship: part_of IDOMAL:0000038 ! antiparasitic humoral response relationship: part_of IDOMAL:0000117 ! phagocytosis during adaptive immune response relationship: part_of IDOMAL:0000601 ! inhibition of invasion created_by: guest creation_date: 2009-11-23T12:21:01Z [Term] id: IDOMAL:0000138 name: neutralization during immune response def: "The ability of antibodies to block the site(s) on parasites, that is being used for entering target cell and/or inhibiting cytoadherance during an immune response." [IB:IB] synonym: "neutralisation during immune response" EXACT [] is_a: IDOMAL:0000561 ! host immune effector process relationship: part_of IDOMAL:0000038 ! antiparasitic humoral response created_by: guest creation_date: 2009-11-23T12:21:01Z [Term] id: IDOMAL:0000139 name: ASO2 def: "ASO2 consists of an oil in water emulsion containing the immunostimulants monophosphoryl lipid A and QS-21, a fraction of Quillaia saponaria." [PIMD:19091034 "BM. Greenwood"] is_a: IDOMAL:0000672 ! chemical compound relationship: has_role IDOMAL:0000136 ! vaccine adjuvant created_by: Ioana creation_date: 2009-12-17T03:52:15Z [Term] id: IDOMAL:0000140 name: antibody-dependent opsonization def: "The process by which a microorganism (or other particulate material) is rendered more susceptible to phagocytosis, by coating with an opsonin, a blood serum protein such as an antibody or complement." [IB:IB] synonym: "antibody dependent opsonization" EXACT [] is_a: GO:0008228 ! opsonization relationship: part_of IDOMAL:0000117 ! phagocytosis during adaptive immune response created_by: guest creation_date: 2009-11-23T02:04:31Z [Term] id: IDOMAL:0000141 name: immunoglobulin G1 def: "It is a monomeric gamma globulin protein consisting of two gamma 1 heavy chains and either two kappa light chains or two lambda light chains, connected by disulfide bonds." [IB:IB] synonym: "IgG1" EXACT [] is_a: IDOMAL:0000765 ! immunoglobulin G relationship: has_role IDOMAL:0000669 ! cytophilic antibody relationship: participates_in IDOMAL:0000123 ! Fc-gamma receptor I recognition relationship: participates_in IDOMAL:0000768 ! cytophilic antibody production created_by: guest creation_date: 2009-11-23T02:08:05Z [Term] id: IDOMAL:0000142 name: non-artemesinin based combination def: "An antimalarial drug combination in which none of the components is artemesinin or one of its derivatrives." [KL:KL] is_a: IDOMAL:0000059 ! antimalarial drug combination relationship: agent_in IDOMAL:0000339 ! non artemisinin based combination therapy created_by: louis creation_date: 2010-03-31T08:19:05Z [Term] id: IDOMAL:0000143 name: artemisinin-based combination def: "An antimalarial drug combination in which one of the components is artemesinin or one of its derivatrives." [KL:KL] synonym: "artemesinin-based combination" EXACT [] is_a: IDOMAL:0000059 ! antimalarial drug combination relationship: agent_in IDOMAL:0000275 ! artemisinin based combination therapy created_by: louis creation_date: 2010-03-31T08:19:05Z [Term] id: IDOMAL:0000144 name: artesunate and chloroquine combination def: "An artemisinin-based combination." [KL:KL] is_a: IDOMAL:0000143 ! artemisinin-based combination created_by: louis creation_date: 2010-03-31T08:23:22Z [Term] id: IDOMAL:0000145 name: artesunate and amodiaquine combination def: "An artemisinin-based combination." [KL:KL] is_a: IDOMAL:0000143 ! artemisinin-based combination created_by: louis creation_date: 2010-03-31T08:23:22Z [Term] id: IDOMAL:0000146 name: artesunate and mefloquine combination def: "An artemisinin-based combination." [KL:KL] is_a: IDOMAL:0000143 ! artemisinin-based combination created_by: louis creation_date: 2010-03-31T08:23:22Z [Term] id: IDOMAL:0000147 name: sporogony def: "The part of the life cycle in the mosquito host, that gives rise to infectious sporozoites." [KL:KL] synonym: "exogenous sexual phase" EXACT [] synonym: "extrinsic incubation period" NARROW [] synonym: "mosquito stages" BROAD [] is_a: IDOMAL:0001058 ! process of malaria pathogen relationship: part_of IDOMAL:0000109 ! Plasmodium life cycle created_by: louis creation_date: 2008-01-21T01:56:00Z [Term] id: IDOMAL:0000148 name: artemether and lumefantrine combination def: "A widely used artemisinin-based combination." [KL:KL] synonym: "Coartem" EXACT [] synonym: "Lonart" EXACT [] synonym: "Riamet" EXACT [] is_a: IDOMAL:0000143 ! artemisinin-based combination created_by: louis creation_date: 2010-03-31T08:23:22Z [Term] id: IDOMAL:0000149 name: lysosome dependent killing def: "The killing of the parasite, and/or parasite components, through lysosome dependent mechanisms." [IB:IB] synonym: "oxygen independent killing" BROAD [] is_a: IDOMAL:0000018 ! fiat process part of malaria host relationship: part_of IDOMAL:0000081 ! phagocytosis, killing of parasite created_by: guest creation_date: 2009-11-20T06:52:45Z [Term] id: IDOMAL:0000150 name: lysosome independent killing def: "The killing of the parasite, and/or parasite components, through lysosome independent mechanisms." [IB:IB] synonym: "oxygen dependent killing" BROAD [] is_a: IDOMAL:0000018 ! fiat process part of malaria host relationship: part_of IDOMAL:0000081 ! phagocytosis, killing of parasite created_by: guest creation_date: 2009-11-20T06:52:45Z [Term] id: IDOMAL:0000151 name: artesunate and sulfadoxine plus pyrimethamine combination def: "An artemisinin-based combination." [KL:KL] synonym: "artesunate and sulfadoxine/pyrimethamine combination" EXACT [] is_a: IDOMAL:0000143 ! artemisinin-based combination created_by: louis creation_date: 2010-03-31T08:23:22Z [Term] id: IDOMAL:0000152 name: defensin def: "Defensins are cysteine-rich cationic proteins. Most defensins function by binding to microbial cell membrane, and once embedded, forming pore-like membrane defects allowing efflux of essential ions and nutrients. Cells of the immune system contain these peptides to assist in killing phagocytized parasites." [IB:IB] is_a: IDOMAL:0001233 ! human host protein relationship: participates_in IDOMAL:0000149 ! lysosome dependent killing created_by: guest creation_date: 2009-11-20T06:55:05Z [Term] id: IDOMAL:0000153 name: sulfadoxine-pyrimethamine def: "An artemisinin-free antimalarial combination." [KL:KL] is_a: IDOMAL:0000142 ! non-artemesinin based combination created_by: louis creation_date: 2010-03-31T08:40:56Z [Term] id: IDOMAL:0000154 name: lysozyme def: "It is a protein encoded by the LYZ gene." [Wikipedia:lysozyme] synonym: "muramidase" EXACT [] synonym: "N-acetylmuramide glycanhydrolase" EXACT [] is_a: IDOMAL:0001233 ! human host protein relationship: participates_in IDOMAL:0000149 ! lysosome dependent killing created_by: guest creation_date: 2009-11-20T06:55:10Z [Term] id: IDOMAL:0000155 name: sulfadoxine-pyrimethamine plus chloroquine def: "An artemisinin-free antimalarial combination." [KL:KL] is_a: IDOMAL:0000142 ! non-artemesinin based combination created_by: louis creation_date: 2010-03-31T08:40:56Z [Term] id: IDOMAL:0000157 name: schizogony def: "The part of the life cycle spent in the vertebrate host." [KL:KL] synonym: "endogenous asexual phase" NARROW [] is_a: IDOMAL:0001058 ! process of malaria pathogen relationship: part_of IDOMAL:0000109 ! Plasmodium life cycle created_by: louis creation_date: 2008-01-21T01:58:00Z [Term] id: IDOMAL:0000158 name: malaria control def: "The sum of measures taken to prevent the spread of malaria; in its wider sense the term also encompasses the goal of dicreasing malaria morbidity leading, ultimately, to its eradication." [KL:KL] is_a: IDOMAL:0000959 ! process of malaria created_by: louis creation_date: 2008-01-21T02:02:00Z [Term] id: IDOMAL:0000161 name: hill malaria def: "Manifestation of malaria epidemic at altitudes in which the disease is usually absent from, or almost always unstable." [KL:KL] is_a: IDOMAL:0000574 ! unstable malaria created_by: louis creation_date: 2008-01-21T02:19:00Z [Term] id: IDOMAL:0000162 name: subtropical seasonal malaria def: "Sharply defined summer epidemics of malaria in areas in which transmission is interrupted from late fall to early spring due to temperatures below the minimum needed." [KL:KL] is_a: IDOMAL:0000029 ! epidemiological type of malaria created_by: louis creation_date: 2008-01-21T02:19:00Z [Term] id: IDOMAL:0000163 name: war and conflict malaria def: "Appearance of malaria in areas from which it is absent or in is seldom found, due to reasons such as movements of people, damage to water distribution, depletion of health services, loss of zzoprophylaxis through cattle, etc." [KL:KL] is_a: IDOMAL:0000029 ! epidemiological type of malaria created_by: louis creation_date: 2008-01-21T02:19:00Z [Term] id: IDOMAL:0000164 name: urban malaria def: "Malaria in urban and suburban areas due to the malfunctioning of water distribution system; often linked to increased urbanization going along with problematic sanitation." [KL:KL] is_a: IDOMAL:0000029 ! epidemiological type of malaria created_by: louis creation_date: 2008-01-21T02:19:00Z [Term] id: IDOMAL:0000165 name: malaria of development workers def: "Appearance of local malaria epidemics die to the assembly of labour force (e.g. \"developments\" leading toi odified environment)." [KL:KL] is_a: IDOMAL:0000029 ! epidemiological type of malaria created_by: louis creation_date: 2008-01-21T02:19:00Z [Term] id: IDOMAL:0000166 name: sulfadoxine-pyrimethamine plus mefloquine def: "An artemisinin-free antimalarial combination." [KL:KL] is_a: IDOMAL:0000142 ! non-artemesinin based combination created_by: louis creation_date: 2010-03-31T08:40:56Z [Term] id: IDOMAL:0000167 name: endemic malaria of high epidemic potential def: "Endemic type of malaria in areas in which, often, non-malarious localities are found; mostly fouund in the plains of South America, India, Sri Lanks and in South-east Asia, etc. Mostly zoophilic vectors usually transmit the disease." [KL:KL] is_a: IDOMAL:0000572 ! endemic malaria created_by: louis creation_date: 2008-01-21T02:22:00Z [Term] id: IDOMAL:0000168 name: endemic malaria of low epidemic potential def: "Highly endemic type of malaria with a very low incidence of epidemics, except for special circumstances (eg major increase of mosquito breeding places). Mostly found in equatorial Africa, hills and foothills of India, etc. Highly anthropophilic vectors usually transmit the disease." [KL:KL] is_a: IDOMAL:0000572 ! endemic malaria created_by: louis creation_date: 2008-01-21T02:22:00Z [Term] id: IDOMAL:0000169 name: malaria vector control def: "The measures taken to reduce exposure of a population to vectors in order to reduce the spread of a vector-borne disease." [KL:KL] is_a: IDOMAL:0001060 ! process of malaria vector population created_by: louis creation_date: 2008-01-21T02:53:00Z [Term] id: IDOMAL:0000170 name: completion of gametogenesis def: "The process of the maturation of gametocytes taking place inside the food bolus in the mosquito midgut." [KL:KL] is_a: IDOMAL:0001058 ! process of malaria pathogen relationship: part_of IDOMAL:0000147 ! sporogony created_by: louis creation_date: 2008-01-22T10:24:00Z [Term] id: IDOMAL:0000171 name: fertilization (sensu Plasmodium) def: "Fertilization of the female gamete by the male microgamete, occuring rapidly after gametogenesis and producing a zygote." [KL:KL] is_a: IDOMAL:0001058 ! process of malaria pathogen relationship: preceded_by IDOMAL:0000170 ! completion of gametogenesis created_by: louis creation_date: 2008-01-22T10:24:00Z [Term] id: IDOMAL:0000172 name: ookinete formation def: "Development of zygote into a banana-shaped and motile form." [KL:KL] is_a: IDOMAL:0001058 ! process of malaria pathogen relationship: preceded_by IDOMAL:0000171 ! fertilization (sensu Plasmodium) created_by: louis creation_date: 2008-01-22T10:24:00Z [Term] id: IDOMAL:0000173 name: traversion of peritrophic membrane def: "The active migration of the ookinete out of the food bolus, through the periptrophic membrane and into the space surrounding the food bolus." [KL:KL] synonym: "traversion of peritrophic matrix" EXACT [] synonym: "traversion of PM" EXACT [] relationship: part_of IDOMAL:0000185 ! invasion of mosquito midgut epithelium created_by: louis creation_date: 2008-01-22T10:24:00Z [Term] id: IDOMAL:0000174 name: invasion of epithelium def: "Active invasion of the epitelial cell of the midgut and exit from the cell. The exit can occur towards a neighboring cell or towards the basal lamina surrounding the midgut." [KL:KL] relationship: preceded_by IDOMAL:0000173 ! traversion of peritrophic membrane created_by: louis creation_date: 2008-01-22T10:24:00Z [Term] id: IDOMAL:0000175 name: attachment to basal lamina def: "Attachment to basal lamina of the ookinete after exiting an epithelial cell." [KL:KL] relationship: preceded_by IDOMAL:0000174 ! invasion of epithelium created_by: louis creation_date: 2008-01-22T10:24:00Z [Term] id: IDOMAL:0000176 name: oocyst formation def: "Transformation of the ookinete into the rounded oocyst." [KL:KL] relationship: preceded_by IDOMAL:0000175 ! attachment to basal lamina created_by: louis creation_date: 2008-01-22T10:24:00Z [Term] id: IDOMAL:0000177 name: oocyst maturation def: "Growth of the oocyst over the period of a 1-3 weeks to a size of tens to hundreds of microns. During this time, multiple nuclear divisions occur. After oocyst maturation is complete, the oocyst divides to form multiple haploid sporozoites." [KL:KL] relationship: preceded_by IDOMAL:0000176 ! oocyst formation created_by: louis creation_date: 2008-01-22T10:24:00Z [Term] id: IDOMAL:0000178 name: rupture of oocyst def: "Rupture of mature oocyst and release into the haemocoel of thousands of immature sporozoites." [KL:KL] relationship: preceded_by IDOMAL:0000177 ! oocyst maturation created_by: louis creation_date: 2008-01-22T10:24:00Z [Term] id: IDOMAL:0000179 name: migration to salivary gland def: "Migration of sporozoites from the site of oocyst rupture to the salivary gland. The sporozoites are surrounded by haemolymph." [KL:KL] relationship: part_of IDOMAL:0000186 ! development of sporozoite created_by: louis creation_date: 2008-01-22T10:24:00Z [Term] id: IDOMAL:0000180 name: invasion of salivary gland def: "Not clearly described events leading to the traversion of the basal lamina and the epitheliam cells of the salivary gland by the sporozoite, which comes to rest in the female-specific parts of the lumen." [KL:KL] relationship: preceded_by IDOMAL:0000179 ! migration to salivary gland created_by: louis creation_date: 2008-01-22T10:24:00Z [Term] id: IDOMAL:0000181 name: maturation of sporozoite in salivary gland def: "Not further defined processes after reaaching the lumen of the salivary gland leading to the infective state of the sporozoite." [KL:KL] relationship: preceded_by IDOMAL:0000180 ! invasion of salivary gland created_by: louis creation_date: 2008-01-22T10:24:00Z [Term] id: IDOMAL:0000182 name: female gametogenesis def: "Female gamete maturation process entailing slight morphological changes, as it becomes enlarged and spherical." [KL:KL] is_a: IDOMAL:0001058 ! process of malaria pathogen relationship: part_of IDOMAL:0000170 ! completion of gametogenesis created_by: louis creation_date: 2008-01-22T10:47:00Z [Term] id: IDOMAL:0000183 name: male gametogenesis def: "Includes the male gamete's DNA three divisions to form eight nuclei. Concurrently, eight flagella are formed that are then shed (exflagellation)." [KL:KL] is_a: IDOMAL:0001058 ! process of malaria pathogen relationship: part_of IDOMAL:0000170 ! completion of gametogenesis created_by: louis creation_date: 2008-01-22T10:53:00Z [Term] id: IDOMAL:0000184 name: exflagellation def: "Pairing of each flagellum with a nucleus to form a microgamete, which separates from the parasite cell." [KL:KL] is_a: IDOMAL:0001058 ! process of malaria pathogen relationship: part_of IDOMAL:0000183 ! male gametogenesis created_by: louis creation_date: 2008-01-22T10:55:00Z [Term] id: IDOMAL:0000185 name: invasion of mosquito midgut epithelium def: "The process during which the ookinete moves out of the food bolus, eventually coming to rest at the basal lamina rurrounding the midgut epithelium." [KL:KL] is_a: IDOMAL:0001058 ! process of malaria pathogen relationship: preceded_by IDOMAL:0000172 ! ookinete formation created_by: louis creation_date: 2008-01-22T11:01:00Z [Term] id: IDOMAL:0000186 name: development of sporozoite def: "All processes from the time of rupture of the oocyst till the moment when the sporozoite has become infective and is located within the salivary gland." [KL:KL] relationship: preceded_by IDOMAL:0000178 ! rupture of oocyst created_by: louis creation_date: 2008-01-22T11:19:00Z [Term] id: IDOMAL:0000187 name: mosquito-borne transmission def: "Classical or normal transmission of malaria through the bite of an anopheline mosquito containing infective sporozoites in its saliva. The sporozoites have developed through the uptake of parasites with a previous bite that occurred at a time that spans the entire sporogonic development (extrinsic incubation period)." [KL:KL] is_a: IDOMAL:0000367 ! horizontal transmission created_by: louis creation_date: 2008-01-22T11:43:00Z [Term] id: IDOMAL:0000188 name: iatrogenic transmission def: "Transmission of malaria to patients due to medical interference, such as transmission by contaminated blood transfusion." [KL:KL] synonym: "accidental transmission" NARROW [] is_a: IDOMAL:0000367 ! horizontal transmission created_by: louis creation_date: 2008-01-22T11:46:00Z [Term] id: IDOMAL:0000189 name: deliberate transmission def: "Historical iatrogenic transmission aiming at therapy of neurosyphilis or, in newer times, for the experimental trials of vaccines or drugs." [KL:KL] is_a: IDOMAL:0000188 ! iatrogenic transmission created_by: louis creation_date: 2008-01-22T11:51:00Z [Term] id: IDOMAL:0000190 name: tetracycline plus quinine def: "An artemisinin-free antimalarial combination." [KL:KL] is_a: IDOMAL:0000142 ! non-artemesinin based combination created_by: louis creation_date: 2010-03-31T08:40:56Z [Term] id: IDOMAL:0000191 name: falciparum malaria def: "A form of malaria caused by an infection with Plasmodium falciparum." [KL:KL] synonym: "Malignant malaria" EXACT [] synonym: "Malignant tertian malaria" EXACT [] is_a: IDOMAL:0000269 ! pathogen specific form of malaria created_by: louis creation_date: 2008-01-22T12:06:00Z [Term] id: IDOMAL:0000192 name: vivax malaria def: "A form of malaria caused by an infection with Plasmodium vivax." [KL:KL] synonym: "Benign tertian malaria" BROAD [] synonym: "Simple tertian malaria" BROAD [] is_a: IDOMAL:0000269 ! pathogen specific form of malaria created_by: louis creation_date: 2008-01-22T12:06:00Z [Term] id: IDOMAL:0000193 name: ovale malaria def: "A form of malaria caused by an infection with Plasmodium ovale." [KL:KL] synonym: "Benign tertian malaria" BROAD [] synonym: "Simple tertian malari" BROAD [] is_a: IDOMAL:0000269 ! pathogen specific form of malaria created_by: louis creation_date: 2008-01-22T12:06:00Z [Term] id: IDOMAL:0000194 name: quartan malaria def: "A form of malaria caused by an infection with Plasmodium malariae." [KL:KL] synonym: "Malariae malaria" RELATED [KL:KL] is_a: IDOMAL:0000269 ! pathogen specific form of malaria created_by: louis creation_date: 2008-01-22T12:06:00Z [Term] id: IDOMAL:0000195 name: monkey malaria def: "Very rare zoonotic or accidental infections of humans with any of, at least, six species of simian malaria parasites." [ISBN034057190X:page45] is_a: IDOMAL:0000269 ! pathogen specific form of malaria created_by: louis creation_date: 2008-01-22T12:20:00Z [Term] id: IDOMAL:0000196 name: non-immune immigrant def: "The term includes immigrant members of populations in malaria-endemic areas who have not yet acquired protective immunity against malaria." [KL:KL] is_a: IDOMAL:0001257 ! non-immune human relationship: part_of IDOMAL:0000685 ! human population of non-immune individuals created_by: louis creation_date: 2008-01-24T10:45:00Z [Term] id: IDOMAL:0000197 name: non-immune immigrant worker def: "Immigrant worker living for a short or longer period in a malarious area and in need of chemoprophylaxis." [KL:KL] is_a: IDOMAL:0000196 ! non-immune immigrant created_by: louis creation_date: 2008-01-24T02:35:00Z [Term] id: IDOMAL:0000198 name: non-immune military personnel def: "Military personnel of a foreign army (regular army or guerilla) arriving to a malarious area and in need of chemoprophylaxis." [kl:KL] is_a: IDOMAL:0000196 ! non-immune immigrant created_by: louis creation_date: 2008-01-24T02:35:00Z [Term] id: IDOMAL:0000199 name: non-immune game warden def: "Non-immune game warden transferred for a short or longer period to a malarious area and in need of chemoprophylaxis." [KL:newKL] is_a: IDOMAL:0000196 ! non-immune immigrant created_by: louis creation_date: 2008-01-24T02:35:00Z [Term] id: IDOMAL:0000200 name: non-immune refugee def: "Member of a refugee population (including economic, war and political unrest) arriving, voluntarily or not, to a malarious area and in need of chemoprophylaxis." [KL:KL] is_a: IDOMAL:0000196 ! non-immune immigrant created_by: louis creation_date: 2008-01-24T02:35:00Z [Term] id: IDOMAL:0000201 name: non-immune traveller def: "Traveller visiting or residing a malarious area and in need of chemoprophylaxis." [KL:KL] synonym: "non-immune tourist" EXACT [] synonym: "tourist" BROAD [] xref: XX:newdbxref is_a: IDOMAL:0000196 ! non-immune immigrant created_by: louis creation_date: 2008-01-24T02:35:00Z [Term] id: IDOMAL:0000202 name: antimalarial drug def: "An antiparasitic drug that is active for the treatment (or the prophylaxis) of malaria." [KL:KL] is_a: IDOMAL:0000203 ! drug created_by: louis creation_date: 2008-01-24T02:51:00Z [Term] id: IDOMAL:0000203 name: drug def: "In pharmacology, a chemical substance used in the treatment, cure, prevention, or diagnosis of disease or used to otherwise enhance physical or mental well-being." [Dictionary.com:drug] is_a: IDOMAL:0000001 ! role created_by: louis creation_date: 2008-01-24T03:10:00Z [Term] id: IDOMAL:0000204 name: 4-aminoquinoline def: "A group of blood schizontocides thought to act by being concentrated in the parasite's lysozyme, inhibiting the polymerization of haemin into haemozoin." [KL:KL] is_a: IDOMAL:0000672 ! chemical compound relationship: has_role IDOMAL:0000258 ! malaria treatment drug created_by: louis creation_date: 2008-01-24T03:18:00Z [Term] id: IDOMAL:0000205 name: sulfone def: "A group of drugs containing a sulfonyl functional group attached to two carbon atoms; they are characterized as type 1 antifolate drugs." [KL:KL] is_a: IDOMAL:0000256 ! type 1 antifolate drug created_by: louis creation_date: 2008-01-24T03:18:00Z [Term] id: IDOMAL:0000206 name: sulfonamide def: "A synthetic antimicrobial drug." [KL:KL] is_a: IDOMAL:0000256 ! type 1 antifolate drug created_by: louis creation_date: 2008-01-24T03:18:00Z [Term] id: IDOMAL:0000207 name: biguanide def: "A group of antimalarials, known as type 2 antifolate drugs due to the specific inhibition of DHF reductase." [KL:KL] synonym: "type 2 antifolate drug" NARROW [] is_a: IDOMAL:0000672 ! chemical compound relationship: has_role IDOMAL:0000258 ! malaria treatment drug created_by: louis creation_date: 2008-01-24T03:18:00Z [Term] id: IDOMAL:0000208 name: 8-aminoquinoline def: "Drugs thought to be particularly active against hypnozoites and gametocytes, believed to be converted to quinone active metabolites in the liver. Used as an anti-relapse drug for vivax and ovale malaria." [KL:KL] is_a: IDOMAL:0000672 ! chemical compound relationship: has_role IDOMAL:0000258 ! malaria treatment drug created_by: louis creation_date: 2008-01-24T03:18:00Z [Term] id: IDOMAL:0000209 name: tetracycline antibiotic def: "Any of a group of related broad-spectrum antibiotics, isolated from species of Streptomyces or produced semisynthetically." [Dorland's Medical Dictionary for Health Consumers:0] comment: A group of broad-spectrum antibiotics, derivatives of poly cyclic naphthacene carboxamide. They have a marked action on blood stages acting as inhibitors of ribosomal protein synthesis. is_a: IDOMAL:0000672 ! chemical compound relationship: has_role IDOMAL:0000643 ! antibiotic created_by: louis creation_date: 2008-01-24T03:18:00Z [Term] id: IDOMAL:0000210 name: peroxide antimalarial drug def: "A group of natural drugs derived from the Chinese medicinal plant Artemisia annua and their synthetic or semi-synthetic analogues." [KL:KL] is_a: IDOMAL:0000672 ! chemical compound relationship: has_role IDOMAL:0000258 ! malaria treatment drug created_by: louis creation_date: 2008-01-24T03:18:00Z [Term] id: IDOMAL:0000211 name: naphthoquinone def: "Slow acting drug acting on the electron transport chain of the malarial mitochondrion." [KL:KL] is_a: IDOMAL:0000672 ! chemical compound relationship: has_role IDOMAL:0000258 ! malaria treatment drug created_by: louis creation_date: 2008-01-24T03:18:00Z [Term] id: IDOMAL:0000212 name: clinical examination def: "Any non-laboratory-assisted process that leads to the presumptive diagnosis of disease." [KL:KL] is_a: IDOMAL:0000049 ! diagnostic procedure of malaria created_by: louis creation_date: 2008-05-13T08:14:49Z [Term] id: IDOMAL:0000213 name: microscopic blood examination def: "A routine procedure leading to the identification of parasites in the blood of patients. The method consists of spreading a film of fresh blood on a slide, and examining it with a microscope after staining." [KL:KL] synonym: "blood film examination" NARROW [] synonym: "thick film examination" NARROW [] is_a: IDOMAL:0000049 ! diagnostic procedure of malaria created_by: louis creation_date: 2008-05-13T08:19:03Z [Term] id: IDOMAL:0000214 name: preparation of blood films def: "The preparation of a slide covered with fresh blood and then stained with Giemsa or Field's stain in order to be viewed under the microscope." [KL:KL] is_a: IDOMAL:0000049 ! diagnostic procedure of malaria relationship: part_of IDOMAL:0000213 ! microscopic blood examination created_by: louis creation_date: 2008-05-13T08:23:41Z [Term] id: IDOMAL:0000215 name: examination of blood films def: "The examination of the blood film under the microscope leading to a semi-quantitative assessment of parasites present (parasite count). Based on characteristics of observed parasites a diagnosis of parasite species can be achieved." [KL:KL] is_a: IDOMAL:0000049 ! diagnostic procedure of malaria relationship: part_of IDOMAL:0000213 ! microscopic blood examination created_by: louis creation_date: 2008-05-13T08:31:46Z [Term] id: IDOMAL:0000216 name: immunological method def: "A diagnostic method based on the use of antibodies, either purified or as an immune serum, that aims at detecting, directly or indirectly, Plasmodium-specific antigens." [KL:KL] is_a: IDOMAL:0000049 ! diagnostic procedure of malaria created_by: louis creation_date: 2008-05-14T07:43:05Z [Term] id: IDOMAL:0000217 name: serological method def: "A method showing the presence of malarial antibodies (from past or present infections) in patient blood." [KL:KL] is_a: IDOMAL:0000216 ! immunological method created_by: louis creation_date: 2008-05-14T07:46:13Z [Term] id: IDOMAL:0000218 name: malarial antigen detection def: "A method devised to detect a malarial antigen and, thus, infection." [KL:KL] is_a: IDOMAL:0000216 ! immunological method created_by: louis creation_date: 2008-05-14T07:46:25Z [Term] id: IDOMAL:0000219 name: pLDH detection method def: "Anyk method using an antibody to detect the presence, in the blood, of the pLDH antigen, present throughout the erythrocytic cycle." [KL:KL] is_a: IDOMAL:0000218 ! malarial antigen detection created_by: louis creation_date: 2008-05-14T07:47:57Z [Term] id: IDOMAL:0000220 name: HRP-2 detection method def: "A dipstick method using a monoclonal antibody to detect the presence, in the blood, of the PfHRP-2 antigen, present throughout the erythrocytic cycle." [KL:KL] is_a: IDOMAL:0000218 ! malarial antigen detection created_by: louis creation_date: 2008-05-14T07:48:07Z [Term] id: IDOMAL:0000221 name: indirect fluorescent antibody test def: "A routine method that detects species-specific malarial parasite antigens in the blood using fluorescent microscopy. Commercial IFAT slides are available from several manufacturers." [KL:KL] synonym: "IFAT" RELATED [KL:KL] is_a: IDOMAL:0000217 ! serological method created_by: louis creation_date: 2008-05-14T07:55:14Z [Term] id: IDOMAL:0000222 name: enzyme-linked immunosorbent assay def: "A method using a soluble malarial antigen to detect infection, performed in microtitre plates and, thus, enabling a large number of samples to be processed." [KL:KL] synonym: "ELISA" EXACT [] is_a: IDOMAL:0000217 ! serological method created_by: louis creation_date: 2008-05-14T08:00:40Z [Term] id: IDOMAL:0000223 name: molecular method def: "A method based on molecular biological techniques aimed at detecting DNA or RNA sequences specific for malaria parasites in the blood of a patient." [KL:KL] is_a: IDOMAL:0000049 ! diagnostic procedure of malaria created_by: louis creation_date: 2008-05-14T08:06:05Z [Term] id: IDOMAL:0000226 name: primaquine def: "An 8-aminoquinoline antimalarial drug." [KL:KL] comment: One of the few drugs killing hypnozoites and,therefore, particularly good for the radical cure of vivax and ovale malaria. All synonyms reflect proprietary names based on the list appearing on "Chemotherapy of Malaria", 2nd edition, WHO 1981. synonym: "Neo-Quipenyl" EXACT [] is_a: IDOMAL:0000208 ! 8-aminoquinoline relationship: agent_in IDOMAL:0000122 ! chemoprophylaxis created_by: louis creation_date: 2008-05-15T08:05:38Z [Term] id: IDOMAL:0000227 name: tafenoquine def: "An 8-aminoquinoline antimalarial drug." [KL:KL] comment: One of the few drugs killing hypnozoites and,therefore, particularly good for the radical cure of vivax and ovale malaria. About ten times more active than primaquine. synonym: "Etaquine" EXACT [] synonym: "WR-238605" EXACT [] is_a: IDOMAL:0000208 ! 8-aminoquinoline relationship: agent_in IDOMAL:0000122 ! chemoprophylaxis created_by: louis creation_date: 2008-05-15T08:05:38Z [Term] id: IDOMAL:0000228 name: tetracycline def: "A tetracycline broad spectrum antibiotic." [American Heritage Medical Dictionary:0, KL:KL] comment: All synonyms reflect proprietary names based on the list appearing on "Chemotherapy of Malaria", 2nd edition, WHO 1981. Additional brand names may be available worldwide. synonym: "Achromycin" EXACT [] synonym: "Cyclomycin" EXACT [] synonym: "Polycycline" EXACT [] synonym: "Tetracyn" EXACT [] is_a: IDOMAL:0000209 ! tetracycline antibiotic relationship: part_of IDOMAL:0000190 ! tetracycline plus quinine created_by: louis creation_date: 2008-05-15T08:16:34Z [Term] id: IDOMAL:0000229 name: doxycycline def: "A tetracycline broad spectrum antibiotic." [KL:KL] comment: All synonyms reflect proprietary names based on the list appearing on "Chemotherapy of Malaria", 2nd edition, WHO 1981. Additional brand names may be available worldwide. synonym: "Biociclina" EXACT [] synonym: "Doxacin" EXACT [] synonym: "Nordox" EXACT [] synonym: "Vibramycin" EXACT [] synonym: "Vibramycin-D" EXACT [] is_a: IDOMAL:0000209 ! tetracycline antibiotic relationship: agent_in IDOMAL:0000122 ! chemoprophylaxis relationship: part_of IDOMAL:0000257 ! doxycycline plus quinine created_by: louis creation_date: 2008-05-15T08:16:34Z [Term] id: IDOMAL:0000230 name: clindamycin def: "A tetracycline broad spectrum antibiotic." [KL:KL] comment: All synonyms reflect proprietary names based on the list appearing on "Chemotherapy of Malaria", 2nd edition, WHO 1981. Additional brand names may be available worldwide. synonym: "Cleocin" RELATED [] is_a: IDOMAL:0000209 ! tetracycline antibiotic created_by: louis creation_date: 2008-05-15T08:16:34Z [Term] id: IDOMAL:0000231 name: lincomycin def: "A tetracycline broad spectrum antibiotic." [KL:KL] comment: All synonyms reflect proprietary names based on the list appearing on "Chemotherapy of Malaria", 2nd edition, WHO 1981. Additional brand names may be available worldwide. synonym: "Lincocin" EXACT [] is_a: IDOMAL:0000209 ! tetracycline antibiotic created_by: louis creation_date: 2008-05-15T08:25:04Z [Term] id: IDOMAL:0000232 name: minocycline def: "A tetracycline broad spectrum antibiotic." [KL:KL] comment: All synonyms reflect proprietary names based on the list appearing on "Chemotherapy of Malaria", 2nd edition, WHO 1981. Additional brand names may be available worldwide. synonym: "Minocin" EXACT [] is_a: IDOMAL:0000209 ! tetracycline antibiotic created_by: louis creation_date: 2008-05-15T08:25:04Z [Term] id: IDOMAL:0000233 name: quinine def: "An arylaminoaccohol schizontocidal drug. Oldest available antimalarial drug." [KL:KL] comment: All synonyms reflect proprietary names based on the list appearing on "Chemotherapy of Malaria", 2nd edition, WHO 1981. synonym: "Adaquin" EXACT [] synonym: "Adquin" EXACT [] synonym: "Bichnine" EXACT [] synonym: "Biquin" EXACT [] synonym: "Biquinate" EXACT [] synonym: "Chinine" EXACT [] synonym: "Coquelusedal" EXACT [] synonym: "Dentogel" EXACT [] synonym: "Grisotets" EXACT [] synonym: "Kinin" EXACT [] synonym: "Kinine" EXACT [] synonym: "Myoquin" EXACT [] synonym: "Quifile" EXACT [] synonym: "Quinamm" EXACT [] synonym: "Quinate" EXACT [] synonym: "Quinbisul" EXACT [] synonym: "Quindan" EXACT [] synonym: "Quine" EXACT [] synonym: "Quinimax" EXACT [] synonym: "Quinoctal" EXACT [] synonym: "Quinoforme" EXACT [] synonym: "Quinsan" EXACT [] is_a: IDOMAL:0000616 ! quinoline methanol relationship: part_of IDOMAL:0000190 ! tetracycline plus quinine relationship: part_of IDOMAL:0000257 ! doxycycline plus quinine created_by: louis creation_date: 2008-05-15T08:27:58Z [Term] id: IDOMAL:0000234 name: mefloquine def: "An arylaminoaccohol schizontocidal drug. Also used as a prophylactic." [KL:KL] synonym: "Lariam" EXACT [] is_a: IDOMAL:0000616 ! quinoline methanol relationship: agent_in IDOMAL:0000122 ! chemoprophylaxis relationship: part_of IDOMAL:0000146 ! artesunate and mefloquine combination relationship: part_of IDOMAL:0000166 ! sulfadoxine-pyrimethamine plus mefloquine created_by: louis creation_date: 2008-05-15T08:27:58Z [Term] id: IDOMAL:0000235 name: halofantrine def: "A synthetic arylaminoaccohol schizontocidal drug." [KL:KL] synonym: "Halfan" NARROW [] is_a: IDOMAL:0000617 ! phenanthrene methanol created_by: louis creation_date: 2008-05-15T08:27:58Z [Term] id: IDOMAL:0000236 name: quinidine def: "An arylaminoaccohol schizontocidal drug." [KL:KL] is_a: IDOMAL:0000616 ! quinoline methanol created_by: louis creation_date: 2008-05-15T08:27:58Z [Term] id: IDOMAL:0000237 name: proguanil def: "A drug of the class of biguanides." [KL:KL] comment: All synonyms reflect proprietary names based on the list appearing on "Chemotherapy of Malaria", 2nd edition, WHO 1981. synonym: "Balusil" NARROW [] synonym: "Bigumal" NARROW [] synonym: "Chlorguanide" NARROW [] synonym: "Chloriguane" NARROW [] synonym: "Diguanyl" NARROW [] synonym: "Drinupal" NARROW [] synonym: "Guanatol" NARROW [] synonym: "Lepadina" NARROW [] synonym: "Paludrine" NARROW [] synonym: "Paludrinol" NARROW [] synonym: "Palusil" NARROW [] synonym: "Plasin" NARROW [] synonym: "Proguanide" NARROW [] synonym: "Tirian" NARROW [] is_a: IDOMAL:0000207 ! biguanide relationship: agent_in IDOMAL:0000122 ! chemoprophylaxis created_by: louis creation_date: 2008-05-15T02:14:51Z [Term] id: IDOMAL:0000238 name: chlorproguanil def: "A drug of the class of biguanides." [KL:KL] is_a: IDOMAL:0000207 ! biguanide created_by: louis creation_date: 2008-05-15T02:14:51Z [Term] id: IDOMAL:0000239 name: cycloguanil def: "A drug of the class of biguanides." [KL:KL] comment: All synonyms reflect proprietary names based on the list appearing on "Chemotherapy of Malaria", 2nd edition, WHO 1981. synonym: "Lapudrine" NARROW [] is_a: IDOMAL:0000207 ! biguanide created_by: louis creation_date: 2008-05-15T02:14:51Z [Term] id: IDOMAL:0000240 name: chlorcycloguanil def: "A drug of the class of biguanides." [KL:KL] is_a: IDOMAL:0000207 ! biguanide created_by: louis creation_date: 2008-05-15T02:14:51Z [Term] id: IDOMAL:0000241 name: pyrimethamine def: "A drug of the class of biguanides." [KL:KL] comment: All synonyms reflect proprietary names based on the list appearing on "Chemotherapy of Malaria", 2nd edition, WHO 1981. synonym: "Chloridin" NARROW [] synonym: "Darapram" NARROW [] synonym: "daraprim" NARROW [] synonym: "Erbaprelina" NARROW [] synonym: "Malocide" NARROW [] synonym: "Pirimecidan" NARROW [] synonym: "Tindurin" NARROW [] is_a: IDOMAL:0000207 ! biguanide relationship: agent_in IDOMAL:0000122 ! chemoprophylaxis relationship: part_of IDOMAL:0000151 ! artesunate and sulfadoxine plus pyrimethamine combination relationship: part_of IDOMAL:0000153 ! sulfadoxine-pyrimethamine relationship: part_of IDOMAL:0000155 ! sulfadoxine-pyrimethamine plus chloroquine relationship: part_of IDOMAL:0000166 ! sulfadoxine-pyrimethamine plus mefloquine created_by: louis creation_date: 2008-05-15T02:43:55Z [Term] id: IDOMAL:0000242 name: atovaquone def: "A drug of the group of naphthoquinones." [KL:KL] synonym: "BW566C80" EXACT [] is_a: IDOMAL:0000211 ! naphthoquinone relationship: agent_in IDOMAL:0000122 ! chemoprophylaxis created_by: louis creation_date: 2008-05-15T02:47:32Z [Term] id: IDOMAL:0000243 name: artemisinine def: "The first natural drug extracted from Artemisia annua." [KL:KL] comment: All synonyms reflect proprietary names based on the list appearing on "Chemotherapy of Malaria", 2nd edition, WHO 1981. synonym: "artemesinin" EXACT [] synonym: "Artenam" NARROW [] synonym: "Paluther" NARROW [] is_a: IDOMAL:0000210 ! peroxide antimalarial drug created_by: louis creation_date: 2008-05-15T02:55:41Z [Term] id: IDOMAL:0000244 name: artemether def: "A peroxide antimalarial drug." [KL:KL] comment: All synonyms reflect proprietary names based on the list appearing on "Chemotherapy of Malaria", 2nd edition, WHO 1981. synonym: "Injectio Artemetheri" NARROW [] is_a: IDOMAL:0000210 ! peroxide antimalarial drug relationship: part_of IDOMAL:0000148 ! artemether and lumefantrine combination created_by: louis creation_date: 2008-05-15T02:55:41Z [Term] id: IDOMAL:0000245 name: arteether def: "A peroxide antimalarial drug." [KL:KL] is_a: IDOMAL:0000210 ! peroxide antimalarial drug created_by: louis creation_date: 2008-05-15T02:55:41Z [Term] id: IDOMAL:0000246 name: artesunate def: "A peroxide antimalarial drug." [KL:KL] is_a: IDOMAL:0000210 ! peroxide antimalarial drug relationship: part_of IDOMAL:0000144 ! artesunate and chloroquine combination relationship: part_of IDOMAL:0000145 ! artesunate and amodiaquine combination relationship: part_of IDOMAL:0000146 ! artesunate and mefloquine combination relationship: part_of IDOMAL:0000151 ! artesunate and sulfadoxine plus pyrimethamine combination created_by: louis creation_date: 2008-05-15T02:55:41Z [Term] id: IDOMAL:0000247 name: artelinic acid def: "A peroxide antimalarial drug." [kl:KL] is_a: IDOMAL:0000210 ! peroxide antimalarial drug created_by: louis creation_date: 2008-05-15T02:55:41Z [Term] id: IDOMAL:0000248 name: lumefantrine def: "An arylaminoaccohol schizontocidal drug. Also used as a prophylactic. Often administered in combination with artemether (Co-artemether)." [KL:KL] synonym: "benflumetol" EXACT [] synonym: "Co-artemether" RELATED [] is_a: IDOMAL:0000052 ! arylaminoalcohol relationship: part_of IDOMAL:0000148 ! artemether and lumefantrine combination created_by: louis creation_date: 2008-05-15T03:16:48Z [Term] id: IDOMAL:0000249 name: diaminodiphenyl sulfone def: "A drug belonging to the class of sulfones." [KL:KL] comment: All synonyms reflect proprietary names based on the list appearing on "Chemotherapy of Malaria", 2nd edition, WHO 1981. synonym: "Avlosulfon" NARROW [] synonym: "Avlosulfone" NARROW [] synonym: "Croysulfone" NARROW [] synonym: "Damitone" NARROW [] synonym: "Daphone" NARROW [] synonym: "DAPS" NARROW [] synonym: "Dapsone" EXACT [] synonym: "Dermosone" NARROW [] synonym: "Diaphelylsulfone" NARROW [] synonym: "Diatox" NARROW [] synonym: "Diphenason" NARROW [] synonym: "Diphone" NARROW [] synonym: "Disulone" NARROW [] synonym: "Dubronax" NARROW [] synonym: "Eporal" NARROW [] synonym: "Novophone" NARROW [] synonym: "Servidapson" NARROW [] synonym: "Sulfadione" NARROW [] synonym: "Sulfona Oral" NARROW [] synonym: "Udolac" NARROW [] is_a: IDOMAL:0000205 ! sulfone created_by: louis creation_date: 2008-05-16T07:35:11Z [Term] id: IDOMAL:0000250 name: acedapsone def: "A drug belonging to the class of sulfones." [KL:KL] comment: All synonyms reflect proprietary names based on the list appearing on "Chemotherapy of Malaria", 2nd edition, WHO 1981. synonym: "Camilan" NARROW [] synonym: "Hansolar" NARROW [] synonym: "Rodilone" NARROW [] synonym: "Sulfadiamine" NARROW [] is_a: IDOMAL:0000205 ! sulfone created_by: louis creation_date: 2008-05-16T07:42:42Z [Term] id: IDOMAL:0000251 name: sulfalene def: "A sulfonamide drug." [KL:KL] comment: All synonyms reflect proprietary names based on the list appearing on "Chemotherapy of Malaria", 2nd edition, WHO 1981. synonym: "Kelfizina" NARROW [] synonym: "Kelfizine" NARROW [] synonym: "Sulfamethoxypyrazine" NARROW [] synonym: "Sulfametopyrazine" NARROW [] is_a: IDOMAL:0000206 ! sulfonamide created_by: louis creation_date: 2008-05-16T07:46:25Z [Term] id: IDOMAL:0000252 name: sulfadimethoxine def: "A sulfonamide drug." [KL:KL] comment: All synonyms reflect proprietary names based on the list appearing on "Chemotherapy of Malaria", 2nd edition, WHO 1981. synonym: "Levisul" NARROW [] synonym: "Madribon" NARROW [] synonym: "Madriquid" RELATED [] synonym: "Sulfadimethoxypyrimidine" NARROW [] is_a: IDOMAL:0000206 ! sulfonamide created_by: louis creation_date: 2008-05-16T07:47:36Z [Term] id: IDOMAL:0000253 name: sulfadiazine def: "A sulfonamide drug." [KL:KL] comment: All synonyms reflect proprietary names based on the list appearing on "Chemotherapy of Malaria", 2nd edition, WHO 1981. synonym: "Adiazine" NARROW [] synonym: "Codiazine" NARROW [] synonym: "Cremodiazine" NARROW [] synonym: "Debenal" NARROW [] synonym: "Diazine" NARROW [] synonym: "Diazyl" NARROW [] synonym: "Eskadiazine" NARROW [] synonym: "Eustral" NARROW [] synonym: "Keladiazine" NARROW [] synonym: "Pirimal" NARROW [] synonym: "Pyrimal" NARROW [] synonym: "Sterazine" NARROW [] synonym: "Sulfazine" NARROW [] is_a: IDOMAL:0000206 ! sulfonamide created_by: louis creation_date: 2008-05-16T07:47:36Z [Term] id: IDOMAL:0000254 name: sulfamethoxypyridazine def: "A sulfonamide drug." [KL:KL] comment: All synonyms reflect proprietary names based on the list appearing on "Chemotherapy of Malaria", 2nd edition, WHO 1981. synonym: "" RELATED [] synonym: "Davosin" NARROW [] synonym: "Deposulfal" NARROW [] synonym: "Depovernil" NARROW [] synonym: "Kynex" NARROW [] synonym: "Lederkyn" NARROW [] synonym: "Midicel" NARROW [] synonym: "Midikel" NARROW [] synonym: "Myasul" NARROW [] synonym: "Spofadiazine" NARROW [] synonym: "Sulfadurazin" NARROW [] synonym: "Sulfalex" RELATED [] synonym: "Sultirene" NARROW [] synonym: "Unosulf" NARROW [] is_a: IDOMAL:0000206 ! sulfonamide created_by: louis creation_date: 2008-05-16T07:47:36Z [Term] id: IDOMAL:0000255 name: sulfadoxine def: "A sulfonamide drug." [KL:KL] comment: All synonyms reflect proprietary names based on the list appearing on "Chemotherapy of Malaria", 2nd edition, WHO 1981. synonym: "Fanasil" NARROW [] synonym: "Fanasulf" NARROW [] synonym: "Fanzil" NARROW [] synonym: "Sulformethoxine" NARROW [] synonym: "Sulforthodimethoxine" NARROW [] synonym: "Sulforthomidine" NARROW [] is_a: IDOMAL:0000206 ! sulfonamide relationship: part_of IDOMAL:0000151 ! artesunate and sulfadoxine plus pyrimethamine combination relationship: part_of IDOMAL:0000153 ! sulfadoxine-pyrimethamine relationship: part_of IDOMAL:0000155 ! sulfadoxine-pyrimethamine plus chloroquine relationship: part_of IDOMAL:0000166 ! sulfadoxine-pyrimethamine plus mefloquine created_by: louis creation_date: 2008-05-16T07:47:36Z [Term] id: IDOMAL:0000256 name: type 1 antifolate drug def: "A substance belonging to a class of drugs acting through the inhibition of the enzyme dihydropteroate synthase." [KL:KL] is_a: IDOMAL:0000672 ! chemical compound relationship: has_role IDOMAL:0000258 ! malaria treatment drug created_by: louis creation_date: 2008-05-16T08:03:07Z [Term] id: IDOMAL:0000257 name: doxycycline plus quinine def: "An artemisinin-free antimalarial combination." [KL:KL] is_a: IDOMAL:0000142 ! non-artemesinin based combination created_by: louis creation_date: 2010-03-31T08:40:56Z [Term] id: IDOMAL:0000258 name: malaria treatment drug def: "A drug commonly used for the treatment of malaria." [KL:KL] is_a: IDOMAL:0000202 ! antimalarial drug relationship: agent_in IDOMAL:0000050 ! chemotherapy of malaria created_by: louis creation_date: 2008-05-16T08:09:53Z [Term] id: IDOMAL:0000259 name: insecticide-treated net def: "An insecticide-treated net is a mosquito net that repels, disables and/or kills mosquitoes coming into contact with insecticide on the netting material. There are two categories of ITNs: conventionally treated nets and long-lasting insecticidal nets." [KL:KL] synonym: "ITN" EXACT [] is_a: IDOMAL:0001026 ! bednet created_by: louis creation_date: 2008-05-16T08:37:08Z [Term] id: IDOMAL:0000260 name: long-lasting insecticidal net def: "A long-lasting insecticidal net is a factory-treated mosquito net made with netting material that has insecticide incorporated within or bound around the fibres. The net must retain its effective biological activity without re-treatment for at least 20 WHO standard washes under laboratory conditions and three years of recommended use under field conditions." [KL:KL] comment: The list of synonyms contains a number of commercially available LLINs and their manufacturer and/or distributor. synonym: "DuraNet (Clarke Mosquito Control)" NARROW [] synonym: "ICONLife (Syngenta)" NARROW [] synonym: "Interceptor Net (BASF)" NARROW [] synonym: "LLIN" EXACT [] synonym: "NetProtect (Intelligent Insect Control)" NARROW [] synonym: "Olyset Net (Sumitomo Chemical)" NARROW [] synonym: "PermaNet (Vestergaard-Frandsen)" NARROW [] is_a: IDOMAL:0000259 ! insecticide-treated net created_by: louis creation_date: 2008-05-16T08:43:07Z [Term] id: IDOMAL:0000261 name: conventionally treated insecticidal net def: "A conventionally treated net is a mosquito net that has been treated by dipping in a WHO-recommended insecticide. To ensure its continued insecticidal effect, the net should be re-treated after three washes, or at least once a year." [KL:KL] synonym: "ITN" BROAD [] is_a: IDOMAL:0000259 ! insecticide-treated net created_by: louis creation_date: 2008-05-16T11:10:58Z [Term] id: IDOMAL:0000262 name: vaccine def: "A vaccine is a preparation which is used to improve immunity to a particular disease." [Wikipedia:vaccine] is_a: IDOMAL:0000001 ! role relationship: agent_in IDOMAL:0000118 ! vaccination of population relationship: agent_in IDOMAL:0001040 ! vaccination created_by: louis creation_date: 2008-05-16T11:20:13Z [Term] id: IDOMAL:0000263 name: ancillary treatment of uncomplicated malaria def: "Therapeutic measures taken, in addition to chemotherapy, to improve the condition of, and cure a patient suffering from uncomplicated malaria." [KL:KL] is_a: IDOMAL:0000051 ! ancillary treatment of malaria created_by: louis creation_date: 2008-05-16T11:46:46Z [Term] id: IDOMAL:0000264 name: ancillary treatment of severe malaria def: "Auxiliary, supportive and secondary treatment for severe malaria not focusing on the parasite." [KL:KL] is_a: IDOMAL:0000051 ! ancillary treatment of malaria created_by: louis creation_date: 2008-05-16T11:46:46Z [Term] id: IDOMAL:0000265 name: rehydration def: "Rehydration is the replenishment of water, or water and electrolytes." [KL:KL] comment: Important aspect of malaria therapy, especially in children and pregnant women, due to increased dehydration through fever in hot climates. is_a: IDOMAL:0001283 ! general therapeutic procedure relationship: part_of IDOMAL:0000263 ! ancillary treatment of uncomplicated malaria created_by: louis creation_date: 2008-05-16T12:08:26Z [Term] id: IDOMAL:0000266 name: antipyretic treatment def: "Treatment of high fever." [KL:KL] comment: Usually reduced through "traditional" measures (eg removal of clothes, sponging of skin, fanning, etc), supported by the administration of antipyretic drugs (eg paracetamol). synonym: "fever reduction" RELATED [] is_a: IDOMAL:0001283 ! general therapeutic procedure relationship: part_of IDOMAL:0000263 ! ancillary treatment of uncomplicated malaria relationship: part_of IDOMAL:0000264 ! ancillary treatment of severe malaria created_by: louis creation_date: 2008-05-16T12:08:26Z [Term] id: IDOMAL:0000267 name: analgesic treatment def: "Treatment of pain." [KL:KL] comment: Usually through the administration of simple pain killers such as paracetamol. is_a: IDOMAL:0001283 ! general therapeutic procedure relationship: part_of IDOMAL:0000263 ! ancillary treatment of uncomplicated malaria created_by: louis creation_date: 2008-05-16T12:08:26Z [Term] id: IDOMAL:0000268 name: treatment for anaemia def: "Treatment of anaemia, often found associated with malaria." [KL:KL] comment: Treatment can be performed through the administration of iron, folic acid, anthelminthics and blood transfusion where safe and available. is_a: IDOMAL:0001283 ! general therapeutic procedure relationship: part_of IDOMAL:0000263 ! ancillary treatment of uncomplicated malaria created_by: louis creation_date: 2008-05-16T12:08:26Z [Term] id: IDOMAL:0000269 name: pathogen specific form of malaria def: "A distinct form of malaria that is caused by a specific species of Plasmodium parasite." [KL:KL] is_a: IDOMAL:0000635 ! quality of malaria created_by: louis creation_date: 2008-05-16T01:06:39Z [Term] id: IDOMAL:0000270 name: cerebral malaria def: "Any impairment of consciousness or convulsions in a patient exposed to malaria." [KL:KL] is_a: IDOMAL:0000271 ! severe malaria created_by: louis creation_date: 2008-05-16T02:03:41Z [Term] id: IDOMAL:0000271 name: severe malaria def: "A form of falciparum malaria where Plasmodium falciparum infections are complicated by serious organ failures or abnormalities in the patient's blood or metabolism." [PT:PT] is_a: IDOMAL:0000191 ! falciparum malaria created_by: louis creation_date: 2008-05-16T02:06:32Z [Term] id: IDOMAL:0000272 name: induced malaria def: "Malaria infection due to medical interference, such as transmission by contaminated blood transfusion or deliberate transmission." [KL:KL] is_a: IDOMAL:0000029 ! epidemiological type of malaria created_by: louis creation_date: 2008-05-16T02:35:27Z [Term] id: IDOMAL:0000273 name: deliberate malaria def: "Historical iatrogenically induced malaria aiming at therapy of neurosyphilis or, in newer times, for the experimental trials of vaccines or drugs." [KL:KL] is_a: IDOMAL:0000272 ! induced malaria created_by: louis creation_date: 2008-05-16T02:39:37Z [Term] id: IDOMAL:0000274 name: malaria combination therapy def: "A form of chemotherapy of malaria using a combination of antimalarial drugs." [KL:KL] is_a: IDOMAL:0000050 ! chemotherapy of malaria created_by: louis creation_date: 2010-03-31T08:46:57Z [Term] id: IDOMAL:0000275 name: artemisinin based combination therapy def: "A combination therapy using artemisinin-based drugs." [KL:KL] synonym: "ACT" EXACT [] synonym: "artemesinin based combination therapy" EXACT [] is_a: IDOMAL:0000274 ! malaria combination therapy created_by: louis creation_date: 2010-03-31T08:49:30Z [Term] id: IDOMAL:0000276 name: natural killer cell activation during immune response def: "The change in morphology and behavior of a natural killer cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [IB:IB] synonym: "NK cell activation during immune response" EXACT [] is_a: GO:0002285 ! lymphocyte activation during immune response relationship: part_of IDOMAL:0000392 ! natural killer cell mediated cytotoxic response created_by: guest creation_date: 2009-11-22T02:59:48Z [Term] id: IDOMAL:0000277 name: coma treatment def: "Treatment of comatose patients according to standard procedures." [KL:KL] synonym: "seizure treatment" RELATED [] is_a: IDOMAL:0001283 ! general therapeutic procedure relationship: part_of IDOMAL:0000264 ! ancillary treatment of severe malaria created_by: louis creation_date: 2008-05-20T08:23:20Z [Term] id: IDOMAL:0000278 name: anticonvulsive treatment def: "Treatment of seizures with standard anticonvulsive drugs such as benzodiazepines." [KL:KL] is_a: IDOMAL:0001283 ! general therapeutic procedure relationship: part_of IDOMAL:0000264 ! ancillary treatment of severe malaria created_by: louis creation_date: 2008-05-20T08:23:20Z [Term] id: IDOMAL:0000279 name: treatment of cerebral oedema def: "Treatment of patients showing signs of cerebral oedema and/or cerebral herniation according to standard procedures." [KL:KL] synonym: "treatment of cerebral edema" EXACT [] is_a: IDOMAL:0001283 ! general therapeutic procedure relationship: part_of IDOMAL:0000264 ! ancillary treatment of severe malaria created_by: louis creation_date: 2008-05-20T08:23:20Z [Term] id: IDOMAL:0000280 name: treatment of severe anaemia def: "Treatment of patients with severe anaemia using packed cells or blood transfusion." [KL:KL] is_a: IDOMAL:0001283 ! general therapeutic procedure relationship: part_of IDOMAL:0000264 ! ancillary treatment of severe malaria created_by: louis creation_date: 2008-05-20T08:23:20Z [Term] id: IDOMAL:0000281 name: treatment of hypoglycaemia def: "Treatment of hypoglycaemic patients according to standard procedures." [KL:KL] is_a: IDOMAL:0001283 ! general therapeutic procedure relationship: part_of IDOMAL:0000264 ! ancillary treatment of severe malaria created_by: louis creation_date: 2008-05-20T08:23:20Z [Term] id: IDOMAL:0000282 name: treatment of intravascular coagulation def: "Treatment of patients showing signs of intravascular coagulation through the administration of vitamin K, fresh-frozen plasma or platelet transfusion." [KL:KL] is_a: IDOMAL:0001283 ! general therapeutic procedure relationship: part_of IDOMAL:0000264 ! ancillary treatment of severe malaria created_by: louis creation_date: 2008-05-20T08:23:20Z [Term] id: IDOMAL:0000283 name: treatment of fluid and electrolyte balance def: "Treatment of dehydrated patients or patients showing signs of a disturbed electrilyte balance according to standard procedures." [KL:KL] is_a: IDOMAL:0001283 ! general therapeutic procedure relationship: part_of IDOMAL:0000264 ! ancillary treatment of severe malaria created_by: louis creation_date: 2008-05-20T08:23:20Z [Term] id: IDOMAL:0000284 name: treatment of renal failure def: "Treatment of showing signs of renal failure according to standard procedures, complemented by the treatment of massive intravascular haemolysis." [KL:KL] is_a: IDOMAL:0001283 ! general therapeutic procedure relationship: part_of IDOMAL:0000264 ! ancillary treatment of severe malaria created_by: louis creation_date: 2008-05-20T08:23:20Z [Term] id: IDOMAL:0000285 name: treatment of pulmonary oedema def: "Treatment of patients showing signs of pulmonary oedema according to standard procedures and/or positive pressure ventilation where possible." [KL:KL] synonym: "treatment of pulmonary edema" EXACT [] is_a: IDOMAL:0001283 ! general therapeutic procedure relationship: part_of IDOMAL:0000264 ! ancillary treatment of severe malaria created_by: louis creation_date: 2008-05-20T08:23:20Z [Term] id: IDOMAL:0000286 name: treatment of septicaemic shock def: "Treatment of patients developing a secondary septicaemic shock according to standard procedures." [KL:KL] is_a: IDOMAL:0001283 ! general therapeutic procedure relationship: part_of IDOMAL:0000264 ! ancillary treatment of severe malaria created_by: louis creation_date: 2008-05-20T08:23:20Z [Term] id: IDOMAL:0000287 name: treatment of secondary bacterial pneumonia def: "Treatment of patients with a secondary pneumonia according to standard procedures." [KL:KL] is_a: IDOMAL:0001283 ! general therapeutic procedure relationship: part_of IDOMAL:0000264 ! ancillary treatment of severe malaria created_by: louis creation_date: 2008-05-20T08:23:20Z [Term] id: IDOMAL:0000288 name: treatment of hyperparasitaemia def: "Treatment of non-immune patients through exchange transfusion." [KL:KL] is_a: IDOMAL:0001283 ! general therapeutic procedure relationship: part_of IDOMAL:0000264 ! ancillary treatment of severe malaria created_by: louis creation_date: 2008-05-20T08:23:20Z [Term] id: IDOMAL:0000289 name: treatment of ruprured spleen def: "Treatment of showing signs of a ruptured spleen according to standard procedures, conservative measures taking precedence over surgery." [KL:KL] is_a: IDOMAL:0001283 ! general therapeutic procedure relationship: part_of IDOMAL:0000264 ! ancillary treatment of severe malaria created_by: louis creation_date: 2008-05-20T08:23:20Z [Term] id: IDOMAL:0000290 name: treatment of metabolic acidosis def: "Treatment of metabolic acidosis in patients according to standard procedures." [KL:KL] is_a: IDOMAL:0001283 ! general therapeutic procedure relationship: part_of IDOMAL:0000264 ! ancillary treatment of severe malaria created_by: louis creation_date: 2008-05-20T08:36:43Z [Term] id: IDOMAL:0000291 name: type 1 malaria vaccine def: "A vaccine aiming at reducing the incidence of severe malaria and malaria-associated mortality in infants and children with heavy exposure to Plasmodium falciparum, such as in sub-Saharan Africa." [ISBN9780340740644:SLHoffman&JEEpstein] is_a: IDOMAL:0001055 ! malaria vaccine created_by: louis creation_date: 2008-05-21T10:48:16Z [Term] id: IDOMAL:0000292 name: type 2 malaria vaccine def: "A vaccine aiming at preventing all clinical manifestations of malaria in individuals from areas with no exposure who travel to regions where malaria is endemic, primarily malaria caused by Plasmodium falciparum and Plasmodium vivax." [ISBN9780340740644:SLHoffman&JEEpstein] is_a: IDOMAL:0001055 ! malaria vaccine created_by: louis creation_date: 2008-05-21T10:48:16Z [Term] id: IDOMAL:0000293 name: transmission blocking vaccine def: "A vaccine aiming at inducing antibodies to attack the sexual stages of the malaria parasite (gametocytes, gametes, zygotes, ookinetes) either in the human host or within the mosquito." [ISBN9780340740644:SLHoffman&JEEpstein] is_a: IDOMAL:0001055 ! malaria vaccine created_by: louis creation_date: 2008-05-21T10:48:16Z [Term] id: IDOMAL:0000295 name: dendritic cell activation during immune response def: "A change in the morphology and behaviour of a dendritic cell resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [IB:IB] synonym: "DC activation during immune response" EXACT [] is_a: GO:0002366 ! leukocyte activation during immune response created_by: guest creation_date: 2009-11-22T02:59:48Z [Term] id: IDOMAL:0000296 name: Plasmodium parasite stage def: "The distinct stages of the life cycle of a protozoon of the genus Plasmodium." [KL:KL] xref: PLO:00001 is_a: IDOMAL:0001058 ! process of malaria pathogen created_by: louis creation_date: 2008-07-31T10:34:09Z [Term] id: IDOMAL:0000297 name: ookinete stage def: "The banana-shaped motile stage of Plasmodium that the zygote develops into. It moves out of the blood bolus through the peritrophic membrane and through the midgut epithelium reaching the basal lamina surrounding the midgut." [KL:KL] xref: PLO:00006 is_a: IDOMAL:0000301 ! invertebrate host stage created_by: louis creation_date: 2008-07-31T11:07:15Z [Term] id: IDOMAL:0000298 name: oocyst stage def: "The stage of developing structure that an ookinete develops into upon reaching, and resting st the basal lamina of the midgut. Sporozoites are produced through endomitosis in the developing oocyst." [KL:KL] xref: PLO:00002 is_a: IDOMAL:0000301 ! invertebrate host stage created_by: louis creation_date: 2008-07-31T11:07:15Z [Term] id: IDOMAL:0000299 name: blood gametocyte stage def: "A blood stage of Plasmodium that, upon transfer to a mosquito with a blood meal, will undergo further development giving rise to gametes." [KL:KL] is_a: IDOMAL:0000308 ! blood stage created_by: louis creation_date: 2008-07-31T11:30:59Z [Term] id: IDOMAL:0000300 name: sporozoite stage def: "The stage of Plasmodium that has been released into the mosquito haemocoel after the rupture of the oocyst. It reaches and penetrates the salivary gland where it stays until transfered into a vertebrate host through a blood meal. It then rapidly invades hepatocytes and is no longer observed in the host." [KL:KL] xref: PLO:00018 is_a: IDOMAL:0000301 ! invertebrate host stage is_a: IDOMAL:0000303 ! exo-erythrocytic stage created_by: louis creation_date: 2008-07-31T11:07:15Z [Term] id: IDOMAL:0000301 name: invertebrate host stage def: "Any life cycle stage of Plasmodium that is spent in the invertebrate host." [PT:PT] synonym: "mosquito stage" EXACT [] xref: PLO:00020 is_a: IDOMAL:0000296 ! Plasmodium parasite stage created_by: louis creation_date: 2008-07-31T11:07:30Z [Term] id: IDOMAL:0000302 name: zygote stage def: "The stage produced through the fusion of male and female gametes." [KL:KL] xref: PLO:00024 is_a: IDOMAL:0000301 ! invertebrate host stage created_by: louis creation_date: 2008-07-31T11:10:10Z [Term] id: IDOMAL:0000303 name: exo-erythrocytic stage def: "Collective name for life cycle stages of Plasmodium referring to the time between inoculation through a blood meal and the first entry into an erythrocyte." [KL:KL] is_a: IDOMAL:0001047 ! vertebrate host stage created_by: louis creation_date: 2008-07-31T11:10:53Z [Term] id: IDOMAL:0000304 name: trophozoite stage def: "A developmental stage of the Plasmodium life cycle found within the erythrocyte." [KL:KL] xref: PLO:00011 is_a: IDOMAL:0000308 ! blood stage created_by: louis creation_date: 2008-07-31T11:19:32Z [Term] id: IDOMAL:0000305 name: ex-hepatocytic merozoite stage def: "A merozoite produced in the liver of the vertebrate host." [KL:KL] xref: PLO:00052 is_a: IDOMAL:0000303 ! exo-erythrocytic stage created_by: louis creation_date: 2008-07-31T11:49:31Z [Term] id: IDOMAL:0000306 name: erythrocytic schizont stage def: "The stage of a sporozoan cell that reproduces by schizogony, producing a varied number of daughter trophozoites or merozoites." [AmericanHeritageMedicalDictionary:0] xref: PLO:00008 is_a: IDOMAL:0000308 ! blood stage created_by: louis creation_date: 2008-07-31T11:58:50Z [Term] id: IDOMAL:0000307 name: hypnozoite stage def: "A collective name for Plasmodium parasites of the relapsing kind that found in the liver of the vertebrate host but have arrested their development." [KL:KL] is_a: IDOMAL:0000303 ! exo-erythrocytic stage created_by: louis creation_date: 2008-07-31T11:13:44Z [Term] id: IDOMAL:0000308 name: blood stage def: "Any life cycle stage of Plasmodium that is spent in the blood of the vertebrate host." [KL:KL] synonym: "erythrocytic stage" EXACT [] is_a: IDOMAL:0001047 ! vertebrate host stage created_by: louis creation_date: 2008-07-31T11:16:53Z [Term] id: IDOMAL:0000310 name: attachment to hepatocyte cell membrane def: "The process of Plasmodium attaching itself to the cell membrane of the hepatocyte." [KL:KL] is_a: IDOMAL:0001058 ! process of malaria pathogen relationship: part_of IDOMAL:0001012 ! hepatocyte invasion created_by: louis creation_date: 2008-07-31T01:03:53Z [Term] id: IDOMAL:0000311 name: formation of parasitophorous vacuole in hepatocyte def: "The process of a parasitophorous vacuole being formed in a hepatocyte." [KL:KL] is_a: IDOMAL:0001058 ! process of malaria pathogen relationship: part_of IDOMAL:0001012 ! hepatocyte invasion created_by: louis creation_date: 2008-07-31T01:05:44Z [Term] id: IDOMAL:0000312 name: use of chemicals def: "Any use of chemicals such as insecticides or repellents for the purpose of vector control." [KL:KL] is_a: IDOMAL:0000000 ! process relationship: part_of IDOMAL:0000667 ! mosquito control created_by: louis creation_date: 2008-08-01T01:37:09Z [Term] id: IDOMAL:0000313 name: mosquito gametocyte stage def: "A life cycle stage of Plasmodium transferred into a mosquito with a blood meal into the midgut, that will undergo further development giving rise to gametes." [KL:KL] is_a: IDOMAL:0000301 ! invertebrate host stage created_by: louis creation_date: 2008-07-31T11:31:38Z [Term] id: IDOMAL:0000314 name: female mosquito gametocyte stage def: "A stage in the mosquito midgut that will later develop into a female gamete stage." [KL:KL] is_a: IDOMAL:0000313 ! mosquito gametocyte stage created_by: louis creation_date: 2008-07-31T11:32:23Z [Term] id: IDOMAL:0000315 name: male mosquito gametocyte stage def: "A gametocyte stage in the mosquito midgut that will later develop into a male gamete stage." [KL:KL] is_a: IDOMAL:0000313 ! mosquito gametocyte stage created_by: louis creation_date: 2008-07-31T11:32:23Z [Term] id: IDOMAL:0000316 name: female blood gametocyte stage def: "A blood stage gametocyte that will later develop into a female gamete." [KL:KL] is_a: IDOMAL:0000299 ! blood gametocyte stage created_by: louis creation_date: 2008-07-31T11:32:57Z [Term] id: IDOMAL:0000317 name: male blood gametocyte stage def: "A blood stage gametocyte that will later develop into a male gamete." [KL:KL] is_a: IDOMAL:0000299 ! blood gametocyte stage created_by: louis creation_date: 2008-07-31T11:32:57Z [Term] id: IDOMAL:0000318 name: macrogamete stage def: "The stage of the mature female gamete of Plasmodium found in the midgut of the mosquito vector." [KL:KL] xref: PLO:00014 relationship: preceded_by IDOMAL:0000314 ! female mosquito gametocyte stage created_by: louis creation_date: 2008-07-31T11:33:09Z [Term] id: IDOMAL:0000319 name: microgamete stage def: "The stage of the mature male gamete of Plasmodium found in the midgut of the mosquito vector, produced through exflagelation of the male gametocyte." [KL:KL] xref: PLO:00005 relationship: preceded_by IDOMAL:0000315 ! male mosquito gametocyte stage created_by: louis creation_date: 2008-07-31T11:33:37Z [Term] id: IDOMAL:0000320 name: ex-erythrocytic merozoite stage def: "A developmental stage that arises from the schizogony of a parent cell in an erythrocyte that may continue the asexual or enter the sexual phase of the Plasmodium life cycle." [KL:KL] xref: PLO:00040 is_a: IDOMAL:0000308 ! blood stage created_by: louis creation_date: 2008-07-31T11:52:15Z [Term] id: IDOMAL:0000321 name: ring trophozoite stage def: "A developmental stage of the Plasmodium life cycle found within the erythrocyte, called such because of the shape observed." [KL:KL] xref: PLO:00015 is_a: IDOMAL:0000304 ! trophozoite stage created_by: louis creation_date: 2008-07-31T11:54:08Z [Term] id: IDOMAL:0000322 name: hepatic schizont stage def: "A schizont produced in the liver of the vertebrate host." [KL:KL] xref: PLO:00009 is_a: IDOMAL:0000303 ! exo-erythrocytic stage created_by: louis creation_date: 2008-07-31T11:59:38Z [Term] id: IDOMAL:0000323 name: malaria eradication def: "The reduction of malaria prevalence in the global human or animal host population to zero." [KL:KL] is_a: IDOMAL:0000959 ! process of malaria created_by: louis creation_date: 2008-08-01T01:45:06Z [Term] id: IDOMAL:0000324 name: preparatory phase of malaria eradication def: "The first phase of an eradication campaign." [KL:KL] relationship: part_of IDOMAL:0000323 ! malaria eradication created_by: louis creation_date: 2008-08-01T01:47:49Z [Term] id: IDOMAL:0000325 name: attack phase of malaria eradication def: "The second phase of an eradication campaign." [KL:KL] relationship: part_of IDOMAL:0000323 ! malaria eradication created_by: louis creation_date: 2008-08-01T01:47:49Z [Term] id: IDOMAL:0000326 name: consolidation phase of malaria eradication def: "The third phase of an eradication campaign." [KL:KL] relationship: part_of IDOMAL:0000323 ! malaria eradication created_by: louis creation_date: 2008-08-01T01:47:49Z [Term] id: IDOMAL:0000327 name: maintenace phase of malaria eradication def: "The fourth and last phase of an eradication campaign." [KL:KL] relationship: part_of IDOMAL:0000323 ! malaria eradication created_by: louis creation_date: 2008-08-01T01:47:49Z [Term] id: IDOMAL:0000328 name: geographical reconnaissance of the area def: "As part of the malaria eradication campaign, geographical reconnaissance of the area to be attacked." [KL:KL] relationship: part_of IDOMAL:0000324 ! preparatory phase of malaria eradication created_by: louis creation_date: 2008-08-01T01:52:07Z [Term] id: IDOMAL:0000329 name: training of field staff def: "As part of the malaria eradication campaign, the training of field staff that will carry out the measures." [KL:KL] relationship: part_of IDOMAL:0000324 ! preparatory phase of malaria eradication created_by: louis creation_date: 2008-08-01T01:52:07Z [Term] id: IDOMAL:0000330 name: identification and numbering sprayable houses/structures def: "As part of the malaria eradication campaign, the identification and numbering sprayable houses/structures through workers surveying the area." [KL:KL] relationship: part_of IDOMAL:0000324 ! preparatory phase of malaria eradication created_by: louis creation_date: 2008-08-01T01:52:07Z [Term] id: IDOMAL:0000331 name: assignment of accommodation def: "As part of the malaria eradication campaign, the assignment of accommodation to workers involved." [KL:KL] relationship: part_of IDOMAL:0000324 ! preparatory phase of malaria eradication created_by: louis creation_date: 2008-08-01T01:52:07Z [Term] id: IDOMAL:0000332 name: assignment of storage facilities def: "As part of the malaria eradication campaign, the assignment of storage facilities for chemicals and other material resources to be used." [KL:KL] relationship: part_of IDOMAL:0000324 ! preparatory phase of malaria eradication created_by: louis creation_date: 2008-08-01T01:52:07Z [Term] id: IDOMAL:0000333 name: procurement of equipment, vehicles, supplies def: "As part of the malaria eradication campaign, the procurement of equipment, vehicles, supplies and chemicals." [KL:KL] relationship: part_of IDOMAL:0000324 ! preparatory phase of malaria eradication created_by: louis creation_date: 2008-08-01T01:52:07Z [Term] id: IDOMAL:0000334 name: residual house spraying in malaria eradication def: "The spraying of houses with residual insecticides during an eradication campaign." [KL:KL] relationship: part_of IDOMAL:0000325 ! attack phase of malaria eradication created_by: louis creation_date: 2008-08-01T01:55:06Z [Term] id: IDOMAL:0000335 name: monitoring degree of transmission in malaria eradication def: "The continuous epidemiological survey of malaria transmission during an eradication campaign." [KL:KL] relationship: part_of IDOMAL:0000325 ! attack phase of malaria eradication created_by: louis creation_date: 2008-08-01T01:57:07Z [Term] id: IDOMAL:0000336 name: surveillance in malaria eradication def: "The epidemiological survey of all malaria indicators during an eradication campaign." [KL:KL] relationship: part_of IDOMAL:0000325 ! attack phase of malaria eradication relationship: part_of IDOMAL:0000326 ! consolidation phase of malaria eradication created_by: louis creation_date: 2008-08-01T02:01:05Z [Term] id: IDOMAL:0000337 name: vigilance by general health services def: "The coninuoys, post-eradication measures taken to guarantee the absence of autochthonous malaria." [KL:KL] relationship: part_of IDOMAL:0000327 ! maintenace phase of malaria eradication created_by: louis creation_date: 2008-08-01T02:06:53Z [Term] id: IDOMAL:0000338 name: Certification of malaria eradication by WHO def: "The last step of an eradication campaign." [KL:KL] relationship: preceded_by IDOMAL:0000327 ! maintenace phase of malaria eradication created_by: louis creation_date: 2008-08-01T02:11:17Z [Term] id: IDOMAL:0000339 name: non artemisinin based combination therapy def: "A combination therapy using non artemisinin-based drugs." [KL:KL] is_a: IDOMAL:0000274 ! malaria combination therapy created_by: louis creation_date: 2010-03-31T08:49:30Z [Term] id: IDOMAL:0000340 name: malaria rapid diagnostic test product def: "A commercial product that provides all necessary components to perform an immunological test for the rapid diagnosis of malaria." [KL:KL] synonym: "RDT" NARROW [] is_a: IDOMAL:0000611 ! object aggregate relationship: participates_in IDOMAL:0000218 ! malarial antigen detection created_by: louis creation_date: 2010-03-31T11:59:17Z [Term] id: IDOMAL:0000341 name: factor def: "A chemical substance, often an enzyme, that plays a crucial role in a biological process." [KL:KL] comment: Role played by portion of physical substance in a biological process. is_a: IDOMAL:0000001 ! role [Term] id: IDOMAL:0000342 name: malaria vector colonization def: "Colonisation is the process by which a vector species spreads into new areas." [KL:KL] comment: The process by which a biotic entity establishes multiple copies of itself in a new environment (including an organismal environment). "native" environment term. is_a: IDOMAL:0001060 ! process of malaria vector population [Term] id: IDOMAL:0000343 name: biotic def: "A living object." [KL:KL] is_a: IDOMAL:0000003 ! object [Term] id: IDOMAL:0000344 name: seroprevalence def: "Prevalence as measured by immunological methods." [KL:KL] is_a: IDOMAL:0000019 ! prevalence of malaria [Term] id: IDOMAL:0000345 name: CareStart Malaria HRP2 (Pf) def: "A commercial RDT from Access Bio, Inc." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000346 name: quality of host def: "A quality which refers to the host." [PT:PT] is_a: IDOMAL:0000002 ! quality [Term] id: IDOMAL:0000347 name: quality of pathogen def: "A quality which refers to the pathogen." [PT:PT] is_a: IDOMAL:0000002 ! quality [Term] id: IDOMAL:0000348 name: interleukin 2 def: "Is a glycoprotein synthesized mainly by CD4 T helper lymphocytes, and has an autocrine effect on the CD4 T cell that produces it." [ISBN:0-8493-1567-0] synonym: "IL-2" EXACT [] is_a: IDOMAL:0001233 ! human host protein relationship: has_role IDOMAL:0000824 ! cytokine relationship: participates_in IDOMAL:0000811 ! T-helper 1 cell mediated cytokine production created_by: guest creation_date: 2009-11-22T03:04:47Z [Term] id: IDOMAL:0000349 name: insecticide resistance def: "A heritable change in the sensitivity of a pest population that is reflected in the repeated failure of a product to achieve the expected level of control when used according to the label recommendation for that pest species." [IRAC:manual] is_a: IDOMAL:0001014 ! quality of vector population [Term] id: IDOMAL:0000350 name: refractoriness def: "The lack of ability of a mosquito to transmit Plasmodium." [KL:KL] is_a: IDOMAL:0001013 ! quality of vector [Term] id: IDOMAL:0000351 name: quality of host population def: "A quality which refers to the host population." [PT:PT] is_a: IDOMAL:0000002 ! quality [Term] id: IDOMAL:0000352 name: herd immunity def: "Resistance of a group to a pathogen due to immunity of a large proportion of the group to that pathogen." [biologyonline:herdimmunity] is_a: IDOMAL:0000351 ! quality of host population [Term] id: IDOMAL:0000353 name: Bacillus israelensis def: "Bacillus thuringiensis serovar israelensis (Bti) is a group of bacteria used as biological control agents for larvae stages of certain Dipterans." [Wikipedia:Bacillusisraelensis] synonym: "Bti" NARROW [] is_a: IDOMAL:0000076 ! bacterium relationship: agent_in IDOMAL:0000905 ! introduction of B. israelensis created_by: louis creation_date: 2009-06-30T02:49:02Z [Term] id: IDOMAL:0000354 name: CareStart Malaria HRP2/pLDH (Pf/PAN) COMBO def: "A commercial RDT from Access Bio, Inc." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000355 name: incubation period def: "The time elapsed between infection with Plasmodium parasite and when symptoms and signs, usually fever, are first apparent." [KL:KL] is_a: IDOMAL:0000092 ! temporal region relationship: part_of IDOMAL:0000091 ! progression of malaria [Term] id: IDOMAL:0000356 name: infectivity period def: "The time period during which a patient can be infectious." [KL:KL] is_a: IDOMAL:0000092 ! temporal region [Term] id: IDOMAL:0000357 name: CareStart Malaria pLDH (PAN) def: "A commercial RDT from Access Bio, Inc." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000359 name: malaria host recovery def: "The process of a malaria host recovering from the disease." [KL:KL] is_a: IDOMAL:0001054 ! process of malaria host [Term] id: IDOMAL:0000360 name: pre-patent period def: "The time from the moment of infection till the first discovery of parasites in the blood." [KL:KL] is_a: IDOMAL:0000092 ! temporal region relationship: part_of IDOMAL:0000355 ! incubation period [Term] id: IDOMAL:0000361 name: Malaria Plasmodium falciparum Rapid test Device (Whole blood) def: "A commercial RDT from ACON Laboratories, Inc." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000362 name: Bacillus thurigiensis def: "Bacillus thuringiensis (or Bt) is a Gram-positive, soil-dwelling bacterium, commonly used as a pesticide." [Wikipedia:newdbxrefBacillusthurigensis] synonym: "Bt" BROAD [] is_a: IDOMAL:0000076 ! bacterium relationship: agent_in IDOMAL:0001021 ! introduction of B. thurigiensis created_by: louis creation_date: 2009-06-30T02:49:02Z [Term] id: IDOMAL:0000363 name: dormancy def: "Dormancy is a state in an organism's life cycle when growth, development, and (in animals) physical activity is temporarily suspended. Specifically, the stages of Plasmodium called hypnozoites, which lead to the relapse of malaria caused by P. ovale or P. vivax. In a wider sense it also includes the cases in which Plasmodium parasites cause recridescence of malaria." [KL:KL] comment: Is a period a process? is_a: IDOMAL:0000103 ! condition of malaria parasite [Term] id: IDOMAL:0000364 name: OnSight-ParaQuick (Pan, Pf) Test def: "A commercial RDT from Amgenix International Inc." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000365 name: AZOG Malaria pf (HRP-II) /pv (pLDH) Antigen Detection Test Device def: "A commercial RDT from AZOG, Inc." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000366 name: vertical transmission def: "Transmission across the placenta from mother to foetus, diagnosed through parasitaemia in the neonate within day 7 post partum." [KL:KL] synonym: "congenital malaria" BROAD [] is_a: IDOMAL:0000082 ! malaria transmission [Term] id: IDOMAL:0000367 name: horizontal transmission def: "Transmission occurring from one individual to another in the same generation." [Wikipedia:transmission] is_a: IDOMAL:0000082 ! malaria transmission [Term] id: IDOMAL:0000368 name: Immunoquick Malaria Falciparum def: "A commercial RDT from Biosynex." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000369 name: Immunoquick Malaria +4 def: "A commercial RDT from Biosynex." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000370 name: toll like receptor def: "Toll like receptors recognize structurally conserved molecules derived from microbes, and play a key role in the innate immune response." [Wikipedia:toll-like receptor] synonym: "TLR" EXACT [] synonym: "toll-like receptor" EXACT [] is_a: IDOMAL:0000373 ! receptor created_by: guest creation_date: 2009-11-22T06:12:55Z [Term] id: IDOMAL:0000371 name: Malaria P.F/Vivax def: "A commercial RDT from Diagnostix Automation/Cortez Diagnostics, Inc." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000372 name: interferon-gamma def: "Is a glycoprotein synthesized by activated T lymphocytes and natural killer cells. It is a powerful activator of mononuclear phagocytes." [ISBN:0-8493-1567-0] synonym: "IFN-gamma" EXACT [] is_a: IDOMAL:0001233 ! human host protein relationship: has_role IDOMAL:0000824 ! cytokine relationship: participates_in GO:0002271 ! plasmacytoid dendritic cell activation during immune response relationship: participates_in GO:0002277 ! myeloid dendritic cell activation during immune response relationship: participates_in GO:0002281 ! macrophage activation during immune response relationship: participates_in IDOMAL:0000276 ! natural killer cell activation during immune response relationship: participates_in IDOMAL:0000471 ! suppression of T-helper 2 cell mediated immune response relationship: participates_in IDOMAL:0000788 ! interferon-gamma production relationship: participates_in IDOMAL:0000811 ! T-helper 1 cell mediated cytokine production created_by: guest creation_date: 2009-11-22T06:25:35Z [Term] id: IDOMAL:0000373 name: receptor def: "A molecule on the surface or within a cell that recognizes and binds with specific molecules, producing a specific effect in the cell." [KL:KL] is_a: IDOMAL:0000001 ! role created_by: guest creation_date: 2009-11-22T06:45:49Z [Term] id: IDOMAL:0000375 name: immunoglobulin G3 def: "It is a monomeric gamma globulin protein consisting of two gamma 3 heavy chains and either two kappa light chains or two lambda light chains, connected by disulfide bonds." [IB:IB] synonym: "IgG3" EXACT [] is_a: IDOMAL:0000765 ! immunoglobulin G relationship: has_role IDOMAL:0000669 ! cytophilic antibody relationship: participates_in IDOMAL:0000123 ! Fc-gamma receptor I recognition relationship: participates_in IDOMAL:0000768 ! cytophilic antibody production created_by: guest creation_date: 2009-11-23T02:08:05Z [Term] id: IDOMAL:0000376 name: interleukin 12 def: "Is a glycoprotein and acts on T cells as a cytotoxic lymphocyte maturation factor as well as natural killer cell stimulatory factor." [ISBN:0-8493-1567-0] synonym: "IL-12" EXACT [] is_a: IDOMAL:0001233 ! human host protein relationship: has_role IDOMAL:0000824 ! cytokine relationship: participates_in IDOMAL:0000276 ! natural killer cell activation during immune response relationship: participates_in IDOMAL:0000811 ! T-helper 1 cell mediated cytokine production created_by: guest creation_date: 2009-11-22T06:54:30Z [Term] id: IDOMAL:0000378 name: macrophage def: "A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells." [CL:0000235] synonym: "histiocyte" EXACT [] is_a: CL:0000766 ! myeloid leukocyte relationship: has_role CL:0000234 ! phagocyte relationship: participates_in GO:0002281 ! macrophage activation during immune response relationship: participates_in GO:0002472 ! macrophage antigen processing and presentation relationship: participates_in IDOMAL:0000078 ! antibody-dependent cell-mediated cytotoxic response created_by: guest creation_date: 2009-11-22T06:57:10Z [Term] id: IDOMAL:0000380 name: OptiMAL-IT def: "A commercial RDT from DiaMed AG." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000381 name: Hexagon Malaria def: "A commercial RDT from Human GmbH." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000382 name: Hexagon Malaria Combi def: "A commercial RDT from Human GmbH." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000383 name: One Step Malaria Antigen Strip def: "A commercial RDT from IND Diagnostic Inc." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000386 name: interleukin 4 def: "Is a glycoprotein produced mainly by CD4 T lymphocytes. One of its many functions is to induce differentiation of T helper 2 cells from naive CD4 T cells." [ISBN:0-8493-1567-0] synonym: "IL-4" EXACT [] is_a: IDOMAL:0001233 ! human host protein relationship: has_role IDOMAL:0000824 ! cytokine relationship: participates_in IDOMAL:0000472 ! suppression of T-helper 1 cell mediated immune response relationship: participates_in IDOMAL:0000812 ! T-helper 2 cell mediated cytokine production created_by: guest creation_date: 2009-11-22T07:17:28Z [Term] id: IDOMAL:0000387 name: interleukin 13 def: "Is a glycoprotein that suppresses cell-mediated immune response. Some of its many effects is suppression of the cytotoxic functions of monocytes/macrophages, and generation of pro-inflammatory cytokines." [IB:IB, ISBN:0-8493-1567-0] synonym: "IL-13" EXACT [] is_a: IDOMAL:0001233 ! human host protein relationship: has_role IDOMAL:0000824 ! cytokine relationship: participates_in IDOMAL:0000812 ! T-helper 2 cell mediated cytokine production created_by: guest creation_date: 2009-11-22T07:17:28Z [Term] id: IDOMAL:0000388 name: CD8-positive, alpha-beta cytotoxic T cell mediated cytotoxic response def: "The directed killing of a target cell by a CD8 T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors." [IB:IB] synonym: "CD8-positive, alpha-beta cytotoxic T lymphocyte mediated cytotoxic response" EXACT [] synonym: "CD8-positive, alpha-beta cytotoxic T-cell mediated cytotoxic response" EXACT [] synonym: "CD8-positive, alpha-beta cytotoxic T-lymphocyte mediated cytotoxic response" EXACT [] is_a: IDOMAL:0000776 ! leukocyte mediated cytotoxic response relationship: part_of IDOMAL:0000747 ! T cell mediated immune response created_by: guest creation_date: 2009-11-22T07:26:07Z [Term] id: IDOMAL:0000389 name: CD4-positive, alpha-beta T cell mediated immune response def: "An immune response involving a change in the state or activity of a CD4-positive, alpha-beta T cell in response to stimulus." [IB:IB] synonym: "CD4-positive, alpha-beta T lymphocyte mediated immune response" EXACT [] synonym: "CD4-positive, alpha-beta T-cell mediated immune response" EXACT [] synonym: "CD4-positive, alpha-beta T-lymphocyte mediated immune response" EXACT [] is_a: IDOMAL:0000747 ! T cell mediated immune response created_by: guest creation_date: 2009-11-22T07:26:07Z [Term] id: IDOMAL:0000390 name: T-helper 1 cell mediated immune response def: "An immune response involving a change in the state or activity of a T-helper 1 cell in response to stimulus." [IB:IB] synonym: "Th1 cell mediated immune response" EXACT [] is_a: IDOMAL:0000389 ! CD4-positive, alpha-beta T cell mediated immune response created_by: guest creation_date: 2009-11-22T07:38:52Z [Term] id: IDOMAL:0000391 name: T-helper 2 cell mediated immune response def: "An immune response involving a change in the state or activity of a T-helper 2 cell in response to stimulus." [IB:IB] synonym: "Th2 cell mediated immune response" EXACT [] is_a: IDOMAL:0000389 ! CD4-positive, alpha-beta T cell mediated immune response created_by: guest creation_date: 2009-11-22T07:38:52Z [Term] id: IDOMAL:0000392 name: natural killer cell mediated cytotoxic response def: "The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors." [IB:IB] is_a: IDOMAL:0000776 ! leukocyte mediated cytotoxic response relationship: part_of GO:0045087 ! innate immune response created_by: guest creation_date: 2009-11-22T07:52:29Z [Term] id: IDOMAL:0000393 name: Fas-induced apoptosis def: "Apoptosis induced by the binding of Fas ligand (FasL/CD95L) to Fas (ApoI/CD95), resulting in signal transduction, which initiates apoptosis." [PMID:11940113 "Bouchier-Hayes D."] synonym: "Death receptor induced apoptosis" BROAD [] synonym: "Fas pathway" BROAD [] is_a: IDOMAL:0000816 ! activation-induced cell death relationship: part_of IDOMAL:0000388 ! CD8-positive, alpha-beta cytotoxic T cell mediated cytotoxic response relationship: part_of IDOMAL:0000392 ! natural killer cell mediated cytotoxic response created_by: guest creation_date: 2009-11-22T07:54:25Z [Term] id: IDOMAL:0000395 name: CD8-positive, alpha-beta cytotoxic T cell degranulation def: "The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a CD8-positive, alpha-beta cytotoxic T cell." [IB:IB] synonym: "CD8-positive, alpha-beta cytotoxic T lymphocyte degranulation" EXACT [] synonym: "CD8-positive, alpha-beta cytotoxic T-cell degranulation" EXACT [] synonym: "CD8-positive, alpha-beta cytotoxic T-lymphocyte degranulation" EXACT [] synonym: "cytotoxic T cell degranulation" BROAD [] synonym: "cytotoxic T cell granule exocytosis" BROAD [] synonym: "cytotoxic T lymphocyte degranulation" BROAD [] synonym: "cytotoxic T lymphocyte granule exocytosis" BROAD [] synonym: "cytotoxic T-cell degranulation" BROAD [] synonym: "cytotoxic T-cell granule exocytosis" BROAD [] synonym: "cytotoxic T-lymphocyte degranulation" BROAD [] synonym: "cytotoxic T-lymphocyte granule exocytosis" BROAD [] is_a: GO:0043299 ! leukocyte degranulation relationship: part_of IDOMAL:0000388 ! CD8-positive, alpha-beta cytotoxic T cell mediated cytotoxic response created_by: guest creation_date: 2009-11-22T07:55:55Z [Term] id: IDOMAL:0000396 name: perforin def: "Is a glycoprotein found in granules of CD8 cytotoxic cells and natural killer cells Upon degranulation, perforin inserts itself into the plasma membrane of the target cell, forming a pore." [Wikipedia:perforin] is_a: IDOMAL:0001233 ! human host protein relationship: participates_in GO:0043320 ! natural killer cell degranulation relationship: participates_in IDOMAL:0000395 ! CD8-positive, alpha-beta cytotoxic T cell degranulation created_by: guest creation_date: 2009-11-22T07:57:10Z [Term] id: IDOMAL:0000397 name: granzyme def: "Serine proteases, released from cytoplasmic granules within natural killer cells and CD8-positive cytotoxic T cells." [IB:IB] synonym: "fragmentin" EXACT [] is_a: IDOMAL:0000729 ! enzyme created_by: guest creation_date: 2009-11-22T07:57:10Z [Term] id: IDOMAL:0000398 name: shivering def: "Involuntary contractions of muscles, mainly of the skin, in response to the chilling effect of low temperatures or fever." [KL:KL] is_a: IDOMAL:0001242 ! clinical feature created_by: louis creation_date: 2010-04-21T02:08:12Z [Term] id: IDOMAL:0000400 name: movement of Plasmodium-erythrocyte junction def: "The movement of Plasmodium-erythrocyte junction along the confronted membranes as merozoite enters the invagination in the erythrocyte surface." [PT:PT] is_a: IDOMAL:0000072 ! pathogen-host interaction relationship: part_of IDOMAL:0000479 ! erythrocyte invasion relationship: preceded_by IDOMAL:0000484 ! sealing erythrocyte after entry created_by: Pantelis creation_date: 2010-04-26T12:44:36Z [Term] id: IDOMAL:0000429 name: usage of insecticides def: "The usage of insecticides, usually for the purpose of mosquito control." [KL:KL] is_a: IDOMAL:0000312 ! use of chemicals created_by: louis creation_date: 2008-08-07T12:54:20Z [Term] id: IDOMAL:0000467 name: Quickstick Malaria Antigen Test def: "A commercial RDT from Innovatek Medical Inc." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000469 name: interleukin 10 def: "Is a glycoprotein that acts as a cytokine synthesis inhibitory factor. Some of its many functions is to inhibit cytokine synthesis by T helper 1 cells and the formation of interferon-gamma." [ISBN:0-8493-1567-0] synonym: "IL-10" EXACT [] is_a: IDOMAL:0001233 ! human host protein relationship: has_role IDOMAL:0000824 ! cytokine relationship: participates_in IDOMAL:0000472 ! suppression of T-helper 1 cell mediated immune response relationship: participates_in IDOMAL:0000759 ! regulatory T cell mediated immune response relationship: participates_in IDOMAL:0000812 ! T-helper 2 cell mediated cytokine production created_by: guest creation_date: 2009-11-23T09:58:25Z [Term] id: IDOMAL:0000470 name: CD8-positive, alpha-beta cytotoxic T cell activation during immune response def: "A change in the morphology and behavior of a CD8-positive, alpha-beta cytotoxic T cell,resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response." [IB:IB] synonym: "CD8-positive, alpha-beta cytotoxic T lymphocyte activation during immune response" EXACT [] synonym: "CD8-positive, alpha-beta cytotoxic T-cell activation during immune response" EXACT [] synonym: "CD8-positive, alpha-beta cytotoxic T-lymphocyte activation during immune response" EXACT [] is_a: GO:0002286 ! T cell activation during immune response relationship: part_of IDOMAL:0000388 ! CD8-positive, alpha-beta cytotoxic T cell mediated cytotoxic response relationship: part_of IDOMAL:0000390 ! T-helper 1 cell mediated immune response created_by: guest creation_date: 2009-11-23T10:08:43Z [Term] id: IDOMAL:0000471 name: suppression of T-helper 2 cell mediated immune response def: "Any process by which T-helper 1 cells stops, prevents or reduces the frequency, rate or extent of T-helper 2 cell mediated immune response." [IB:IB] synonym: "suppression of Th2 cell mediated immune response" EXACT [] relationship: part_of IDOMAL:0000390 ! T-helper 1 cell mediated immune response created_by: guest creation_date: 2009-11-23T10:08:43Z [Term] id: IDOMAL:0000472 name: suppression of T-helper 1 cell mediated immune response def: "Any process by which T-helper 2 cells stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell mediated immune response." [IB:IB] synonym: "suppression of Th1 cell mediated immune response" EXACT [] relationship: part_of IDOMAL:0000391 ! T-helper 2 cell mediated immune response created_by: guest creation_date: 2009-11-23T10:10:56Z [Term] id: IDOMAL:0000473 name: erythrocytic schizogony def: "A developmental process in the erythrocytes leading to the production of schizonts." [KL:KL] synonym: "erythrocytic schizogeny" EXACT [] is_a: IDOMAL:0001058 ! process of malaria pathogen relationship: part_of IDOMAL:0000157 ! schizogony created_by: Administrator creation_date: 2008-06-22T07:41:20Z [Term] id: IDOMAL:0000474 name: ADVANCED QUALITY One Step Malaria (p.f.) Test (whole blood) def: "A commercial RDT from IntecProducts, Inc." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000475 name: pre-erythrocytic schizogony def: "A developmental process in the liver leading to the production of schizonts." [ISBN:034057190X "Essential Malariology third edition p. 14"] synonym: "primary exo-erythrocytic schizogony" EXACT [ISBN:034057190X "Essebtial Malariology third edition p.16"] synonym: "primary tissue schizogony" EXACT [] is_a: IDOMAL:0001058 ! process of malaria pathogen relationship: part_of IDOMAL:0000157 ! schizogony created_by: Administrator creation_date: 2008-06-22T07:44:15Z [Term] id: IDOMAL:0000476 name: hypnozoites formation def: "The process of formation of a hypnozoite in the liver of the vertebrate host." [KL:KL] is_a: IDOMAL:0001058 ! process of malaria pathogen relationship: part_of IDOMAL:0000475 ! pre-erythrocytic schizogony created_by: Administrator creation_date: 2008-06-22T07:51:00Z [Term] id: IDOMAL:0000477 name: merozoite formation def: "The process during which a merozoite is formed." [KL:KL] is_a: IDOMAL:0001058 ! process of malaria pathogen relationship: part_of IDOMAL:0000473 ! erythrocytic schizogony relationship: part_of IDOMAL:0000475 ! pre-erythrocytic schizogony created_by: Administrator creation_date: 2008-06-22T07:55:09Z [Term] id: IDOMAL:0000479 name: erythrocyte invasion def: "The phase where merozoites invade the erythrocytes." [ISBN:034057190X "Essential Malariology third edition, p 18"] is_a: IDOMAL:0001006 ! Plasmodium penetration of vertebrate host relationship: part_of IDOMAL:0000473 ! erythrocytic schizogony created_by: Administrator creation_date: 2008-06-22T08:07:12Z [Term] id: IDOMAL:0000480 name: Plasmodium recognition and attachment to erythrocyte def: "The process in which the apical end of merozoite makes initial contact with the erythrocyte, creating a depression in erythrocyte membrane." [PMID:96121 "J Cell Biol. 1978 Apr;77(1):72-82. Erythrocyte entry by malarial parasites. A moving junction between erythrocyte and parasite by Aikawa et al at"] is_a: IDOMAL:0000072 ! pathogen-host interaction is_a: IDOMAL:0001058 ! process of malaria pathogen relationship: part_of IDOMAL:0000479 ! erythrocyte invasion relationship: preceded_by IDOMAL:0000481 ! Plasmodium-erythrocyte junction formation created_by: Administrator creation_date: 2008-06-22T08:10:41Z [Term] id: IDOMAL:0000481 name: Plasmodium-erythrocyte junction formation def: "The process of erythrocyte's membrane thickening in the area where merozoite is attached." [PMID:96121 "J Cell Biol. 1978 Apr;77(1):72-82. J Cell Biol. 1978 Apr;77(1):72-82. by Aikawa et al"] is_a: IDOMAL:0000072 ! pathogen-host interaction is_a: IDOMAL:0001058 ! process of malaria pathogen relationship: part_of IDOMAL:0000479 ! erythrocyte invasion relationship: preceded_by IDOMAL:0000400 ! movement of Plasmodium-erythrocyte junction created_by: Administrator creation_date: 2008-06-22T08:11:55Z [Term] id: IDOMAL:0000482 name: vacuole creation is_obsolete: true created_by: Administrator creation_date: 2008-06-22T08:12:24Z [Term] id: IDOMAL:0000483 name: entrance to the vacuole def: "The entrance of a cell into a vacuole while invading a foreign organism." [KL:KL] is_a: IDOMAL:0001058 ! process of malaria pathogen created_by: Administrator creation_date: 2008-06-22T08:13:54Z [Term] id: IDOMAL:0000484 name: sealing erythrocyte after entry def: "The closing of the orifice behind the merozoite as the entry in the erythrocyte it is been completed." [PT:PT] is_a: IDOMAL:0000072 ! pathogen-host interaction is_a: IDOMAL:0001058 ! process of malaria pathogen relationship: part_of IDOMAL:0000479 ! erythrocyte invasion created_by: Administrator creation_date: 2008-06-22T08:14:35Z [Term] id: IDOMAL:0000485 name: trophozoite formation def: "The process during which a trophozoite is formed." [KL:KL] synonym: "ring form parasite" RELATED [] xref: ISBN:034057190X "Essential Malariology third edition" is_a: IDOMAL:0001058 ! process of malaria pathogen relationship: part_of IDOMAL:0000473 ! erythrocytic schizogony created_by: Administrator creation_date: 2008-06-22T08:16:51Z [Term] id: IDOMAL:0000486 name: schizogonic periodicity def: "The time length of each phase of the erythrocytic cycle of the parasite." [KL:KL] is_a: IDOMAL:0000347 ! quality of pathogen created_by: Administrator creation_date: 2008-06-22T08:23:55Z [Term] id: IDOMAL:0000487 name: clinical manifestation of malaria def: "The exhibition of any of the combined symptoms and signs of malaria." [KL:KL] is_a: IDOMAL:0000635 ! quality of malaria relationship: part_of IDOMAL:0000091 ! progression of malaria created_by: Administrator creation_date: 2008-06-22T08:37:03Z [Term] id: IDOMAL:0000488 name: febrile paroxysm def: "The characteristic, clinical feature of recurrent fever attacks in malaria." [KL:KLnewdbxref] is_a: IDOMAL:0001054 ! process of malaria host relationship: realizes IDOMAL:0000518 ! generic clinical manifestation of malaria created_by: Administrator creation_date: 2008-06-22T08:43:42Z [Term] id: IDOMAL:0000489 name: Bacillus sphaericus def: "Bacillus sphaericus is an obligate aerobe bacterium used as a larvicide for mosquito control." [Wikipedia:Bacillussphaericus] is_a: IDOMAL:0000076 ! bacterium relationship: agent_in IDOMAL:0000907 ! introduction of B. sphaericus created_by: louis creation_date: 2009-06-30T02:49:02Z [Term] id: IDOMAL:0000490 name: malaise def: "Malaise is a \"general feeling of being unwell\"." [KL:KL] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0001282 ! prodromal stage created_by: Administrator creation_date: 2008-06-22T08:46:43Z [Term] id: IDOMAL:0000491 name: fatigue def: "Physical fatigue is the inability to continue functioning at the level of one's normal abilities." [Wikipedia:fatigue] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0001282 ! prodromal stage created_by: Administrator creation_date: 2008-06-22T08:47:02Z [Term] id: IDOMAL:0000492 name: lassitude def: "Lassitude is a weariness." [KL:KL] synonym: "exhaustion" NARROW [] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0001282 ! prodromal stage created_by: Administrator creation_date: 2008-06-22T08:47:16Z [Term] id: IDOMAL:0000493 name: headache def: "In medicine a headache is a symptom of a number of different conditions of the head and sometimes neck." [KL:KL] synonym: "Cephalalgia " EXACT [] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0001282 ! prodromal stage created_by: Administrator creation_date: 2008-06-22T08:47:55Z [Term] id: IDOMAL:0000494 name: dizziness def: "Dizziness refers to an impairment in spatial perception and stability." [Wikipedia:newdbxrefdizziness] synonym: "vertigo" NARROW [] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0001282 ! prodromal stage created_by: Administrator creation_date: 2008-06-22T08:48:14Z [Term] id: IDOMAL:0000495 name: anorexia def: "Anorexia is the symptom of poor appetite whatever the cause." [Wikipedia:Wikipedia] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0001282 ! prodromal stage created_by: Administrator creation_date: 2008-06-22T08:48:36Z [Term] id: IDOMAL:0000496 name: nausea def: "Nausea is the sensation of unease and discomfort in the stomach with an urge to vomit." [Wikipedia:nausea] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000506 ! hot stage relationship: happens_during IDOMAL:0001282 ! prodromal stage created_by: Administrator creation_date: 2008-06-22T08:48:45Z [Term] id: IDOMAL:0000497 name: vomiting def: "Vomiting (known medically as emesis and informally as throwing up and a number of other terms) is the forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose." [Wikipedia:vomiting] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000506 ! hot stage relationship: happens_during IDOMAL:0001282 ! prodromal stage created_by: Administrator creation_date: 2008-06-22T08:48:52Z [Term] id: IDOMAL:0000498 name: cold stage def: "The first phase of the febrile paroxysm, characterized by chills, lasting for 15 to 60 minutes." [KL:KL] is_a: IDOMAL:0001054 ! process of malaria host relationship: part_of IDOMAL:0000488 ! febrile paroxysm created_by: Administrator creation_date: 2008-06-22T08:49:40Z [Term] id: IDOMAL:0000499 name: mild shivering def: "A milder form of shivering." [KL:KL] is_a: IDOMAL:0000398 ! shivering relationship: happens_during IDOMAL:0000498 ! cold stage created_by: Administrator creation_date: 2008-06-22T08:50:22Z [Term] id: IDOMAL:0000500 name: teeth chattering def: "An uncontrolled vibration of the teeth, often at night or in cases of feeling cold." [KL:KL] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000498 ! cold stage created_by: Administrator creation_date: 2008-06-22T08:50:50Z [Term] id: IDOMAL:0000501 name: rigor def: "Rigor is a shaking occurring during a high fever." [Wikipedia:rigor] synonym: "body shake" RELATED [] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000498 ! cold stage created_by: Administrator creation_date: 2008-06-22T08:51:13Z [Term] id: IDOMAL:0000502 name: peripheral vasoconstriction def: "Constriction of a peripheral blood vessels." [KL:KL] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000498 ! cold stage created_by: Administrator creation_date: 2008-06-22T08:52:52Z [Term] id: IDOMAL:0000503 name: rapid pulse def: "A pulse faster than normal." [KL:KL] synonym: "tachycardia" RELATED [] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000498 ! cold stage relationship: happens_during IDOMAL:0000506 ! hot stage created_by: Administrator creation_date: 2008-06-22T08:53:15Z [Term] id: IDOMAL:0000504 name: low volume pulse def: "The pulse occurring when the stroke volume of the heart or when the pulse pressure decreases." [KL:KL] synonym: "pulsus parvus" EXACT [] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000498 ! cold stage created_by: Administrator creation_date: 2008-06-22T08:53:47Z [Term] id: IDOMAL:0000505 name: febrile convulsions def: "A febrile is a convulsion triggered by a rise in body temperature." [KL:KL] synonym: "febrile seizure" EXACT [] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000498 ! cold stage created_by: Administrator creation_date: 2008-06-22T08:54:24Z [Term] id: IDOMAL:0000506 name: hot stage def: "The second phase of the febrile paroxysm, characterized by high fever and several symptoms due to this, lasting from 2 to 6 hours." [KL:KL] synonym: "flush phase symptom" EXACT [] is_a: IDOMAL:0001054 ! process of malaria host relationship: part_of IDOMAL:0000488 ! febrile paroxysm created_by: Administrator creation_date: 2008-06-22T08:54:55Z [Term] id: IDOMAL:0000507 name: severe throbbing headache def: "A severe headache that gives the impression that one's blood vessels in the head are throbbing." [KL:KL] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000506 ! hot stage created_by: Administrator creation_date: 2008-06-22T08:55:57Z [Term] id: IDOMAL:0000508 name: palpitation def: "A palpitation is an abnormal awareness of the beating of the heart, whether it is too slow, too fast, irregular, or at its normal frequency." [KL:KL] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000506 ! hot stage created_by: Administrator creation_date: 2008-06-22T08:56:35Z [Term] id: IDOMAL:0000509 name: tachypnoea def: "A state characterized by rapid breathing." [KL:KL] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000506 ! hot stage created_by: Administrator creation_date: 2008-06-22T08:56:51Z [Term] id: IDOMAL:0000510 name: prostration def: "Total exhaustion or weakness, often including collapse." [KL:KL] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000506 ! hot stage created_by: Administrator creation_date: 2008-06-22T08:57:17Z [Term] id: IDOMAL:0000511 name: postural syncope def: "A syncope that occurs upon assuming an upright position and is caused by inadequate blood flow to the brain resulting from failure of normal vasoconstrictive mechanisms." [KL:KL] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000506 ! hot stage created_by: Administrator creation_date: 2008-06-22T08:57:32Z [Term] id: IDOMAL:0000512 name: epigastric disconfort def: "Not very intense pain in the epigastric area." [KL:KL] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000506 ! hot stage created_by: Administrator creation_date: 2008-06-22T08:57:53Z [Term] id: IDOMAL:0000513 name: delirium def: "Delirium is an acute and relatively sudden (developing over hours to days) decline in attention-focus, perception, and cognition." [Wikipedia:delirium] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000506 ! hot stage created_by: Administrator creation_date: 2008-06-22T09:00:31Z [Term] id: IDOMAL:0000514 name: splenic enlargement def: "Enlargement of the spleen." [KL:KL] synonym: "splenomegalia" EXACT [] synonym: "splenomegaly" EXACT [] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000506 ! hot stage created_by: Administrator creation_date: 2008-06-22T09:01:50Z [Term] id: IDOMAL:0000515 name: sweating stage def: "The third phase of the febrile paroxysm, characterized by intense sweating, during which the fever falls and all symptoms diminish while the patient usually sleeps." [KL:KL] is_a: IDOMAL:0001054 ! process of malaria host relationship: part_of IDOMAL:0000488 ! febrile paroxysm created_by: Administrator creation_date: 2008-06-22T09:02:38Z [Term] id: IDOMAL:0000516 name: fever def: "Fever is a frequent medical sign that describes an increase in internal body temperature to levels above normal." [KL:KL] synonym: "febrile response" NARROW [] synonym: "pyrexia" EXACT [] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000506 ! hot stage created_by: Administrator creation_date: 2008-06-22T09:03:57Z [Term] id: IDOMAL:0000517 name: sweating def: "Sweating is the production of a fluid, consisting primarily of water as well as various dissolved solids, that is excreted by the sweat glands in the skin of mammals." [KL:KL] synonym: "Perspiration" EXACT [] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000515 ! sweating stage created_by: Administrator creation_date: 2008-06-22T09:04:20Z [Term] id: IDOMAL:0000518 name: generic clinical manifestation of malaria def: "The exhibition of any of the combined symptoms and signs of malaria found in all forms." [KL:KL] is_a: IDOMAL:0000487 ! clinical manifestation of malaria created_by: Administrator creation_date: 2008-06-22T09:29:08Z [Term] id: IDOMAL:0000519 name: clinical manifestation of specific type of malaria def: "The exhibition of any of the combined symptoms and signs of specific forms of malaria caused by distinct parasites." [KL:KL] is_a: IDOMAL:0000487 ! clinical manifestation of malaria created_by: Administrator creation_date: 2008-06-22T09:31:25Z [Term] id: IDOMAL:0000520 name: clinical manifestation of falciparum malaria def: "The exhibition of any of the combined symptoms and signs of specific forms of malaria caused by P. falciparum." [KL:KL] synonym: "malignant malaria clinical feature" EXACT [] synonym: "sub-tertian malaria clinical feature" RELATED [] synonym: "symptomatologyy of falciparum malaria." NARROW [] synonym: "tertian malaria clinical feature" EXACT [] is_a: IDOMAL:0000519 ! clinical manifestation of specific type of malaria created_by: Administrator creation_date: 2008-06-22T10:22:52Z [Term] id: IDOMAL:0000521 name: Coelomyces def: "A fungal genus." [KL:KL] is_a: IDOMAL:0000077 ! fungus created_by: louis creation_date: 2009-06-30T02:56:29Z [Term] id: IDOMAL:0000522 name: anaemia def: "Anaemia is a decrease in normal number of red blood cells or less than the normal quantity of hemoglobin in the blood." [KL:KL] synonym: "Anemia" EXACT [] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000520 ! clinical manifestation of falciparum malaria created_by: Administrator creation_date: 2008-06-22T10:30:56Z [Term] id: IDOMAL:0000523 name: hyperpyrexia def: "Exceptionally high fever." [KL:KL] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000520 ! clinical manifestation of falciparum malaria created_by: Administrator creation_date: 2008-06-22T10:31:44Z [Term] id: IDOMAL:0000524 name: hyperparasitaemia def: "A clinical feature of a high number of parasites in the blood, usually higher than 500000 per microlitrer." [KL:KL] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000520 ! clinical manifestation of falciparum malaria created_by: Administrator creation_date: 2008-06-22T10:32:01Z [Term] id: IDOMAL:0000525 name: hypoglycaemia def: "An abnormally diminished concentration of glucose in the blood." [KL:KL] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000520 ! clinical manifestation of falciparum malaria created_by: Administrator creation_date: 2008-06-22T10:32:19Z [Term] id: IDOMAL:0000526 name: renal failure def: "The inability of the kidney to excrete metabolites at normal plasma levels under normal loading, or inability to retain electrolytes when intake is normal." [KL:KL] synonym: "kidney failure" EXACT [] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000520 ! clinical manifestation of falciparum malaria created_by: Administrator creation_date: 2008-06-22T10:32:48Z [Term] id: IDOMAL:0000527 name: hepatic dysfunction def: "Malfunction of the liver." [KL:KL] synonym: "hepatic disfunction" EXACT [] synonym: "hepatic malfunction" EXACT [] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000520 ! clinical manifestation of falciparum malaria created_by: Administrator creation_date: 2008-06-22T10:32:57Z [Term] id: IDOMAL:0000528 name: water-electrolyte imbalance def: "Any situation in which the levels of one of the common electrolytes is either elevated or lowered in the serum of a patient." [KL:KL] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000520 ! clinical manifestation of falciparum malaria created_by: Administrator creation_date: 2008-06-22T10:33:19Z [Term] id: IDOMAL:0000529 name: pulmonary oedema def: "Swelling and/or fluid accumulation in the lungs." [KL:KL] synonym: "pulmonary edema" EXACT [] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000520 ! clinical manifestation of falciparum malaria created_by: Administrator creation_date: 2008-06-22T10:33:52Z [Term] id: IDOMAL:0000530 name: massive intravascular haemolysis def: "Higher than usual intravascular haemolysis usually associated with severe malaria." [KL:KL] synonym: "blackwater fever" RELATED [] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000520 ! clinical manifestation of falciparum malaria created_by: Administrator creation_date: 2008-06-22T10:34:33Z [Term] id: IDOMAL:0000531 name: splenic rupture def: "The result of blunt injury to the spleen leading to its laceration, and haemorrhage from it." [KL:KL] synonym: "rupture of the spleen" EXACT [] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000520 ! clinical manifestation of falciparum malaria created_by: Administrator creation_date: 2008-06-22T10:35:34Z [Term] id: IDOMAL:0000532 name: circulatory collapse def: "A circulatory collapse is defined as a general or specific failure of the circulation, either cardiac or peripheral in nature." [KL:KL] is_a: IDOMAL:0001242 ! clinical feature relationship: happens_during IDOMAL:0000520 ! clinical manifestation of falciparum malaria created_by: Administrator creation_date: 2008-06-22T10:39:38Z [Term] id: IDOMAL:0000533 name: clinical manifestation of vivax malaria def: "The exhibition of any of the combined symptoms and signs of specific forms of malaria caused by P. vivax." [KL:KL] is_a: IDOMAL:0000519 ! clinical manifestation of specific type of malaria created_by: Administrator creation_date: 2008-06-22T10:40:48Z [Term] id: IDOMAL:0000534 name: clinical manifestation of ovale malaria def: "The exhibition of any of the combined symptoms and signs of specific forms of malaria caused by P. ovale." [KL:KL] is_a: IDOMAL:0000519 ! clinical manifestation of specific type of malaria created_by: Administrator creation_date: 2008-06-22T10:41:26Z [Term] id: IDOMAL:0000535 name: clinical manifestation of quartan malaria def: "The exhibition of any of the combined symptoms and signs of specific forms of malaria caused by P. malariae." [KL:KL] is_a: IDOMAL:0000519 ! clinical manifestation of specific type of malaria created_by: Administrator creation_date: 2008-06-22T10:42:00Z [Term] id: IDOMAL:0000536 name: clinical manifestation of monkey malaria def: "The exhibition of any of the combined symptoms and signs of specific forms of malaria caused by monkey malaria parasites." [KL:KL] is_a: IDOMAL:0000519 ! clinical manifestation of specific type of malaria created_by: Administrator creation_date: 2008-06-22T10:43:16Z [Term] id: IDOMAL:0000537 name: innate resistance to malaria def: "The non-specific defences already present in the body which are stimulated by malaria parasite infection." [PT:PT] is_a: IDOMAL:0000012 ! immunity created_by: Administrator creation_date: 2008-06-22T11:07:40Z [Term] id: IDOMAL:0000538 name: resistance due to red cell polymorphism def: "Resistance to malaria due to conditions affecting the structure of beta globin chains, the rate of synthesis of globin chains, the level of G6PD and conditions affecting the red cell membrane or cytoskeleton." [KL:KL] is_a: IDOMAL:0000537 ! innate resistance to malaria created_by: Administrator creation_date: 2008-06-22T11:09:02Z [Term] id: IDOMAL:0000539 name: Culicinomyces def: "A fungal genus." [KL:KL] is_a: IDOMAL:0000077 ! fungus created_by: louis creation_date: 2009-06-30T02:56:29Z [Term] id: IDOMAL:0000540 name: Lagenidium def: "A genus of mold-like brown algae." [KL:KL] is_a: IDOMAL:0000541 ! brown alga created_by: louis creation_date: 2009-06-30T02:56:29Z [Term] id: IDOMAL:0000541 name: brown alga def: "The Phaeophyceae or brown algae, (singular: alga) is a large group of mostly marine multicellular algae, including many seaweeds of colder Northern Hemisphere waters." [Wikipedia:newdbxrefbrownalgae] is_a: IDOMAL:0000343 ! biotic created_by: louis creation_date: 2009-06-30T03:00:29Z [Term] id: IDOMAL:0000542 name: Binax Now Malaria def: "A commercial RDT from Inverness Medical Innovations, Inc." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000543 name: acquired immunity to malaria def: "Immunity to malaria gradually acquired by infection." [KL:KL] is_a: IDOMAL:0000012 ! immunity created_by: Administrator creation_date: 2008-06-22T11:21:48Z [Term] id: IDOMAL:0000544 name: pre-erythrocytic immunity def: "Immunity against pre-erythrocytic stages of Plasmodium, especially sporozoites." [KL:KL] is_a: IDOMAL:0000543 ! acquired immunity to malaria created_by: Administrator creation_date: 2008-06-22T11:22:19Z [Term] id: IDOMAL:0000545 name: immunity to erythrocytic stage def: "Immunity against parasites that have reached the erythrocytic stage." [KL:KL] is_a: IDOMAL:0000543 ! acquired immunity to malaria created_by: Administrator creation_date: 2008-06-22T11:23:12Z [Term] id: IDOMAL:0000546 name: immunity to sexual stage def: "Immunity against parasites that have reached the sexual stage." [KL:KL] is_a: IDOMAL:0000543 ! acquired immunity to malaria created_by: Administrator creation_date: 2008-06-22T11:23:39Z [Term] id: IDOMAL:0000547 name: Advantage Pan Malaria Card def: "A commercial RDT from J. Mitra & Co. Pvt. LTD." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000548 name: Advantage P.f. Malaria Card def: "A commercial RDT from J. Mitra & Co. Pvt. LTD." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000549 name: immunoglobulin E production def: "The appearance of immunoglobulin E due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [IB:IB] synonym: "IgE production" EXACT [] is_a: GO:0002381 ! immunoglobulin production during immune response relationship: part_of IDOMAL:0000391 ! T-helper 2 cell mediated immune response created_by: guest creation_date: 2009-11-23T10:43:13Z [Term] id: IDOMAL:0000550 name: Advantage Mal Card def: "A commercial RDT from J. Mitra & Co. Pvt. LTD." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000551 name: staining def: "Staining is an auxiliary technique used in microscopy to enhance contrast in the microscopic image." [Wikipedia:staining] is_a: IDOMAL:0000049 ! diagnostic procedure of malaria relationship: part_of IDOMAL:0000213 ! microscopic blood examination created_by: Administrator creation_date: 2008-06-22T11:59:19Z [Term] id: IDOMAL:0000552 name: Giemsa staining def: "Giemsa stain, named after Gustav Giemsa, an early malariologist, is used for the histopathological diagnosis of malaria and other parasites." [Wikipedia:Giemsa] is_a: IDOMAL:0000551 ! staining created_by: Administrator creation_date: 2008-06-23T12:00:26Z [Term] id: IDOMAL:0000553 name: Field's staining def: "Field's stain is a histological method for staining of blood smears." [Wikipedia:Field'sstain] is_a: IDOMAL:0000551 ! staining created_by: Administrator creation_date: 2008-06-23T12:00:43Z [Term] id: IDOMAL:0000554 name: immunoglobulin E def: "It is a monomeric immunoglobulin consisting of two epsilon heavy chains and either two kappa light chains or two lambda light chains, connected by disulfide bonds." [IB:IB] synonym: "IgE" EXACT [] is_a: IDOMAL:0000764 ! immunoglobulin relationship: participates_in IDOMAL:0000549 ! immunoglobulin E production created_by: guest creation_date: 2009-11-23T10:43:27Z [Term] id: IDOMAL:0000555 name: Paracheck Pf Rapid test for P. falciparum Malaria (Device) def: "A commercial RDT from Orchid Biomedical Systems." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000556 name: Paracheck Pf Rapid test for P. falciparum Malaria (Dipstick) def: "A commercial RDT from Orchid Biomedical Systems." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000557 name: indirect haemagglutination test def: "An assay for the presence of specific antiviral antibodies in a test serum." [TheFreeDictionary:hemaglutinationinhibitiontest] synonym: "hemagglutination inhibition (HI) test" RELATED [] synonym: "IHA test" EXACT [] synonym: "indirect hemagglutination test" EXACT [] is_a: IDOMAL:0000217 ! serological method created_by: Administrator creation_date: 2008-06-23T12:07:30Z [Term] id: IDOMAL:0000558 name: immuno-precipitation def: "The technique of precipitating a protein antigen out of solution using an antibody that specifically binds to that particular protein." [Wikipedia:immunoprecipitation] is_a: IDOMAL:0000217 ! serological method created_by: Administrator creation_date: 2008-06-23T12:08:20Z [Term] id: IDOMAL:0000559 name: First Response Malaria Ag HRP2 def: "A commercial RDT from Premier Medical Corporation Ltd." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000560 name: First Response Malaria Ag Combo (pLDH/HRP2) def: "A commercial RDT from Premier Medical Corporation Ltd." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000561 name: host immune effector process def: "Any host process of the immune system that occurs as part of an immune response." [IB:IB] is_a: IDOMAL:0000005 ! host immune system process relationship: part_of IDOMAL:0000006 ! host immune response created_by: guest creation_date: 2009-12-02T11:02:50Z [Term] id: IDOMAL:0000562 name: use of nucleic acid probe def: "Any method using nucleic acid probes for the detection of malaria." [KL:KL] is_a: IDOMAL:0000223 ! molecular method created_by: Administrator creation_date: 2008-06-23T12:12:00Z [Term] id: IDOMAL:0000563 name: quality of the environment def: "A quality which refers to the environment." [PT:PT] is_a: IDOMAL:0000002 ! quality created_by: Administrator creation_date: 2008-06-23T09:28:03Z [Term] id: IDOMAL:0000564 name: arthropod def: "Arthropods are invertebrate animals belonging to the Phylum Arthropoda that have an exoskeleton (external skeleton), a segmented body, and jointed attachments called appendages." [KL:KL] is_a: IDOMAL:0000343 ! biotic created_by: Administrator creation_date: 2008-06-23T08:54:24Z [Term] id: IDOMAL:0000565 name: insect def: "Insects (Class Insecta) are arthropods, having a hard exoskeleton, a three-part body (head, thorax, and abdomen), three pairs of jointed legs, compound eyes, and two antennae." [Wikipedia:Insect] is_a: IDOMAL:0000564 ! arthropod created_by: Administrator creation_date: 2008-06-23T08:54:35Z [Term] id: IDOMAL:0000566 name: diptera def: "Insects, members of the order Diptera (Greek: di = two, and pteron = wing), possessing a single pair of wings on the mesothorax and a pair of halteres, derived from the hind wings, on the metathorax." [KL:KL] synonym: "True flies" NARROW [] is_a: IDOMAL:0000565 ! insect created_by: Administrator creation_date: 2008-06-23T08:54:48Z [Term] id: IDOMAL:0000567 name: complement activation, classical pathway def: "Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for opsonization or direct killing of pathogens." [IB:IB] is_a: IDOMAL:0000810 ! complement activation relationship: part_of IDOMAL:0000140 ! antibody-dependent opsonization created_by: guest creation_date: 2009-11-23T02:10:13Z [Term] id: IDOMAL:0000568 name: temperature def: "Degree of hotness or coldness measured on a definite scale." [MerriamWebsterOnline:temperature] is_a: IDOMAL:0000563 ! quality of the environment created_by: Administrator creation_date: 2008-06-23T09:35:31Z [Term] id: IDOMAL:0000569 name: humidity def: "A moderate degree of wetness especially of the atmosphere." [MerriamWebsterOnline:humidity] is_a: IDOMAL:0000563 ! quality of the environment created_by: Administrator creation_date: 2008-06-23T09:35:48Z [Term] id: IDOMAL:0000570 name: wind def: "A natural movement of air of any velocity." [MerriamWebsterOnline:wind] is_a: IDOMAL:0000563 ! quality of the environment created_by: Administrator creation_date: 2008-06-23T09:36:34Z [Term] id: IDOMAL:0000571 name: endemicity def: "The fact that autochthonous cases of malaria can be present at varying frequencies in an area or community." [KL:KL] is_a: IDOMAL:0001050 ! disposition created_by: Administrator creation_date: 2008-06-23T09:41:43Z [Term] id: IDOMAL:0000572 name: endemic malaria def: "A term applied to malaria when there is a constant measurable incidence both of cases of the disease and of its natural transmission in an area over a succession of years." [KL:KL] is_a: IDOMAL:0000029 ! epidemiological type of malaria created_by: Administrator creation_date: 2008-06-23T09:54:17Z [Term] id: IDOMAL:0000573 name: stable malaria def: "Classification of malaria denoting that the amount of transmission hardly fluctuates from year to year, but with possible seasonal fluctuation." [KL:KL] is_a: IDOMAL:0000029 ! epidemiological type of malaria created_by: Administrator creation_date: 2008-06-23T09:44:30Z [Term] id: IDOMAL:0000574 name: unstable malaria def: "Classification of malaria denoting that the amount of transmission varies from year to year." [KL:KL] is_a: IDOMAL:0000029 ! epidemiological type of malaria created_by: Administrator creation_date: 2008-06-23T09:44:30Z [Term] id: IDOMAL:0000575 name: ICT Malaria Pf Cassette Test (ML01) def: "A commercial RDT from ICT Diagnostics." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000576 name: autochthonous malaria def: "A case of malaria resulting from the bite of a mosquito in a malaria-endemic region." [KL:KL] synonym: "indigenous malaria" RELATED [] is_a: IDOMAL:0000029 ! epidemiological type of malaria created_by: Administrator creation_date: 2008-06-23T10:16:25Z [Term] id: IDOMAL:0000577 name: ICT Malaria Combo Cassette Test (ML02) def: "A commercial RDT from ICT Diagnostics." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000578 name: imported malaria def: "A case of malaria resulting from the bite of a mosquito in a non malaria region that was carried into non malaria region through any means of transportation." [KL:KL] is_a: IDOMAL:0000029 ! epidemiological type of malaria created_by: Administrator creation_date: 2008-06-23T09:53:10Z [Term] id: IDOMAL:0000579 name: introduced malaria def: "Cases of malaria contracted locally but derived from imported cases." [KL:KL] is_a: IDOMAL:0000029 ! epidemiological type of malaria created_by: Administrator creation_date: 2008-06-23T09:53:10Z [Term] id: IDOMAL:0000580 name: Parahit-f DIPSTICK FOR FALCIPARUM MALARIA def: "A commercial RDT from Span Diagnostics Ltd." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000581 name: C3b def: "C3b is the principal protein fragment produced when complement component C3 is cleaved by convertases of either the classical or alternative pathway. C3b aids in opsonization." [IB:IB] synonym: "complement component 3b" EXACT [] is_a: IDOMAL:0001233 ! human host protein relationship: participates_in IDOMAL:0000104 ! complement receptor 1 recognition relationship: participates_in IDOMAL:0000567 ! complement activation, classical pathway relationship: participates_in IDOMAL:0000795 ! complement activation, alternative pathway created_by: guest creation_date: 2009-11-23T02:17:58Z [Term] id: IDOMAL:0000582 name: inhibition of sequestration def: "To limit or fully inhibiting the extent of parasite sequestration of the walls of host inner blood vessels." [IB:IB] relationship: part_of IDOMAL:0000138 ! neutralization during immune response created_by: guest creation_date: 2009-11-23T02:34:23Z [Term] id: IDOMAL:0000583 name: hypoendemicity def: "Hypoendemicity denotes areas where there is little malaria transmission and the effects of malaria on the general population are unimportant." [ISBN:034057190X "Essential Malariology third edition p.131"] is_a: IDOMAL:0000571 ! endemicity created_by: Administrator creation_date: 2008-06-23T10:22:38Z [Term] id: IDOMAL:0000584 name: mesoendemicity def: "Mesoendemicity is found typically among small rural communities in the subtropical zones with varying intensity of transmission depending on local circumstances." [ISBN:034057190X "Essential Malariology third edition p.131"] is_a: IDOMAL:0000571 ! endemicity created_by: Administrator creation_date: 2008-06-23T10:22:38Z [Term] id: IDOMAL:0000585 name: hyperendemicity def: "Hyperendemicity is seen in areas with intense but seasonal transmission where the immunity is insufficient to prevent the effects of malaria on all age groups." [ISBN:034057190X "Essential Malariology third edition p.131"] is_a: IDOMAL:0000571 ! endemicity created_by: Administrator creation_date: 2008-06-23T10:22:38Z [Term] id: IDOMAL:0000586 name: holoendemicity def: "Holoendemicity denotes a perennial transmission of high degree, resulting in a considerable degree of immune response to all age groups, but particularly in the adults." [ISBN:034057190X "Essential Malariology third edition p.131"] is_a: IDOMAL:0000571 ! endemicity created_by: Administrator creation_date: 2008-06-23T10:22:38Z [Term] id: IDOMAL:0000587 name: malaria survey def: "Evaluation of the amount and condition of transmission of the disease." [ISBN:034057190X "Essential Malariology third edition , p131"] synonym: "malariometry" BROAD [] is_a: IDOMAL:0001037 ! process of malaria epidemiology created_by: Administrator creation_date: 2008-06-23T10:42:42Z [Term] id: IDOMAL:0000588 name: Parahit-f TEST DEVICE FOR FALCIPARUM MALARIA def: "A commercial RDT from Span Diagnostics Ltd." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000589 name: collection of epidemiological data def: "The collection of data relating to the epidemiology of malaria, to be processed and used for the survey of the state of the disease in a given area." [KL:KL] is_a: IDOMAL:0000587 ! malaria survey created_by: Administrator creation_date: 2008-06-23T10:50:15Z [Term] id: IDOMAL:0000590 name: investigation relating to the human host def: "Any investigation aiming at finding the malarial state of an individual." [KL:KL] is_a: IDOMAL:0000587 ! malaria survey created_by: Administrator creation_date: 2008-06-23T10:50:15Z [Term] id: IDOMAL:0000591 name: investigation relating to the insect vector def: "Any investigation aiming at finding the transmission potential state of a vector population." [KL:KL] is_a: IDOMAL:0000587 ! malaria survey created_by: Administrator creation_date: 2008-06-23T10:50:15Z [Term] id: IDOMAL:0000592 name: spleen examination def: "Any process carried out to determine the condition of a patient's spleen." [KL:KL] is_a: IDOMAL:0000590 ! investigation relating to the human host created_by: Administrator creation_date: 2008-06-23T10:50:48Z [Term] id: IDOMAL:0000593 name: blood examination def: "An examination of the blood comprised of several, different diagnostic procedures." [KL:KL] is_a: IDOMAL:0000590 ! investigation relating to the human host created_by: Administrator creation_date: 2008-06-23T10:50:48Z [Term] id: IDOMAL:0000594 name: estimation of mosquito density def: "The calculated approximation of the mosquito density in an area which is usable even if input data may be incomplete or uncertain." [KL:KL] is_a: IDOMAL:0000591 ! investigation relating to the insect vector created_by: Administrator creation_date: 2008-06-23T10:51:36Z [Term] id: IDOMAL:0000595 name: estimation of natural infection def: "The calculated approximation of the natural infection rate in an area which is usable even if input data may be incomplete or uncertain." [KL:KL] is_a: IDOMAL:0000591 ! investigation relating to the insect vector created_by: Administrator creation_date: 2008-06-23T10:51:36Z [Term] id: IDOMAL:0000596 name: estimation of biting habits def: "The calculated approximation of the biting habits of a vector which is usable even if input data may be incomplete or uncertain." [KL:KL] is_a: IDOMAL:0000591 ! investigation relating to the insect vector created_by: Administrator creation_date: 2008-06-23T10:51:36Z [Term] id: IDOMAL:0000597 name: estimation of longevity def: "The estimation of the life span of vectors." [KL:KL] is_a: IDOMAL:0000591 ! investigation relating to the insect vector created_by: Administrator creation_date: 2008-06-23T10:51:36Z [Term] id: IDOMAL:0000598 name: nematocera def: "Nematocera are generally primitive flies, typically recognized by filamentous, multi-segmented antennae which may be plumose in some males." [Wikipedia:Nematocera] is_a: IDOMAL:0000566 ! diptera created_by: Administrator creation_date: 2008-06-23T07:42:19Z [Term] id: IDOMAL:0000599 name: culicidae def: "A family of insects found around the world comprising all mosquitoes." [KL:KL] is_a: IDOMAL:0000598 ! nematocera created_by: Administrator creation_date: 2008-06-23T07:42:34Z [Term] id: IDOMAL:0000600 name: anophelinae def: "A genus comprising a large number of mosquitoes." [KL:KL] is_a: IDOMAL:0000599 ! culicidae created_by: Administrator creation_date: 2008-06-23T07:43:10Z [Term] id: IDOMAL:0000601 name: inhibition of invasion def: "To limit or fully inhibiting the extent of parasite invasion of host hepatocytes and/or erythrocytes." [IB:IB] relationship: part_of IDOMAL:0000138 ! neutralization during immune response created_by: guest creation_date: 2009-11-23T02:34:23Z [Term] id: IDOMAL:0000602 name: Parahit-Total Device Rapid test for P. falciparum and Pan malarial species def: "A commercial RDT from Span Diagnostics Ltd." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000603 name: patient def: "A person under health care. The person may be waiting for this care or may be receiving it or may have already received it." [PT:MedicineNET.com "http://www.medterms.com/script/main/art.asp?articlekey=39154"] is_a: IDOMAL:0000001 ! role created_by: Administrator creation_date: 2008-06-23T08:00:07Z [Term] id: IDOMAL:0000604 name: human def: "A human is a member of a species of bipedal primates in the family Hominidae (taxonomically Homo sapiens)." [Wikipedia:human] synonym: "Homo sapiens" EXACT [] is_a: IDOMAL:0001220 ! ape relationship: has_role IDOMAL:0000603 ! patient created_by: Administrator creation_date: 2008-06-23T08:00:34Z [Term] id: IDOMAL:0000605 name: mammal def: "A vertebrate animal of the class Mammalia." [KL:KL] is_a: IDOMAL:0001274 ! vertebrate relationship: has_role IDOMAL:0001062 ! malaria host created_by: Administrator creation_date: 2008-06-23T08:01:48Z [Term] id: IDOMAL:0000606 name: primate def: "A primate is a member of the biological order Primates, the group that contains lemurs, the Aye-aye, lorisids, galagos, tarsiers, monkeys, and apes, with the last category including great apes." [Wikipedia:Primate] is_a: IDOMAL:0000605 ! mammal created_by: Administrator creation_date: 2008-06-23T08:01:58Z [Term] id: IDOMAL:0000607 name: SD BIOLINE Malaria Ag def: "A commercial RDT from Standard Diagnostics, Inc." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000608 name: protection against mosquito bites def: "A process protecting a human host from the biting of mosquitoes, usually through physical or chemical means." [KL:KL] relationship: part_of IDOMAL:0000119 ! malaria prevention in individuals created_by: Administrator creation_date: 2008-06-24T11:17:53Z [Term] id: IDOMAL:0000609 name: SD BIOLINE Malaria Ag Pf def: "A commercial RDT from Standard Diagnostics, Inc." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000610 name: SD BIOLINE Malaria Ag Pf/Pan def: "A commercial RDT from Standard Diagnostics, Inc." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000611 name: object aggregate def: "A independent continuant entity that is a mereological sum of separate objects." [BFO:SNAP "http://www.ifomis.org/bfo/manual p48"] created_by: Pantelis creation_date: 2008-08-08T12:45:08Z [Term] id: IDOMAL:0000612 name: Anopheles developmental stage def: "The developmental stages of mosquitoes belonging to the genus Anopheles." [KL:KL] is_a: IDOMAL:0001059 ! process of malaria vector created_by: Pantelis creation_date: 2008-08-21T10:54:28Z [Term] id: IDOMAL:0000613 name: FirstSign-Malaria Pf Card Test def: "A commercial RDT from Unimed International, Inc." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000614 name: phagocyte activation during immune response def: "A change in the morphology or behavior of a phagocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [IB:IB] is_a: GO:0002263 ! cell activation during immune response relationship: part_of IDOMAL:0000117 ! phagocytosis during adaptive immune response relationship: part_of IDOMAL:0000124 ! phagocytosis during innate immune response created_by: guest creation_date: 2009-11-23T06:20:00Z [Term] id: IDOMAL:0000616 name: quinoline methanol def: "A compound used as an antimalarial drug." [KL:KL] is_a: IDOMAL:0000052 ! arylaminoalcohol created_by: Administrator creation_date: 2008-06-23T08:43:02Z [Term] id: IDOMAL:0000617 name: phenanthrene methanol def: "A compound used as an antimalarial drug." [KL:KL] is_a: IDOMAL:0000052 ! arylaminoalcohol created_by: Administrator creation_date: 2008-06-23T08:43:02Z [Term] id: IDOMAL:0000618 name: granzyme B def: "It is a protein encoded by the GZMB gene." [Wikipedia:GZMB] synonym: "granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1" EXACT [] is_a: IDOMAL:0001233 ! human host protein relationship: has_role IDOMAL:0000397 ! granzyme relationship: participates_in GO:0043320 ! natural killer cell degranulation relationship: participates_in IDOMAL:0000395 ! CD8-positive, alpha-beta cytotoxic T cell degranulation created_by: guest creation_date: 2009-11-23T06:49:24Z [Term] id: IDOMAL:0000619 name: FirstSign-ParaView-2 (Pv + Pf) Card Test def: "A commercial RDT from Unimed International, Inc." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000620 name: T cell receptor recognition def: "The process by which a T cell receptor in the malaria host interprets its surroundings." [IB:IB] synonym: "T-cell receptor recognition" EXACT [] synonym: "TcR recognition" EXACT [] is_a: IDOMAL:0000697 ! receptor recognition relationship: part_of IDOMAL:0000747 ! T cell mediated immune response created_by: guest creation_date: 2009-11-24T10:07:02Z [Term] id: IDOMAL:0000621 name: B cell receptor recognition def: "The process by which a B cell receptor in the malaria host interprets its surroundings." [IB:IB] synonym: "BcR recognition" EXACT [] is_a: IDOMAL:0000697 ! receptor recognition relationship: part_of IDOMAL:0000748 ! B cell mediated immune response created_by: guest creation_date: 2009-11-24T10:07:02Z [Term] id: IDOMAL:0000622 name: Malaria Rapid Pf def: "A commercial RDT from Vision Biotech (Pty) Ltd." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000623 name: Malaria Rapid Combo def: "A commercial RDT from Vision Biotech (Pty) Ltd." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000624 name: Malaria Rapid Dual def: "A commercial RDT from Vision Biotech (Pty) Ltd." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000625 name: Wondfo One Step Malaria Pf/Pan Whole Blood Test def: "A commercial RDT from Guangzhou Wondfo Biotech Co., Ltd." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000626 name: benzonaphthyridine def: "Any derivative of benzonaphthyridine that is used as an antimalarial, often in cases of cerebral malaria." [KL:KL] is_a: IDOMAL:0000672 ! chemical compound relationship: has_role IDOMAL:0000258 ! malaria treatment drug created_by: Administrator creation_date: 2008-06-23T08:51:13Z [Term] id: IDOMAL:0000627 name: mepacrine def: "An antimalarial drug." [KL:KL] is_a: IDOMAL:0000672 ! chemical compound relationship: has_role IDOMAL:0000258 ! malaria treatment drug created_by: Administrator creation_date: 2008-06-23T08:51:17Z [Term] id: IDOMAL:0000628 name: pyronaridine def: "A compound used as an antimalarial drug." [KL:KL] is_a: IDOMAL:0000626 ! benzonaphthyridine created_by: Administrator creation_date: 2008-06-23T08:51:34Z [Term] id: IDOMAL:0000629 name: Parascreen Rapid Test for Malaria Pan/Pf (Device) def: "A commercial RDT from Zephyr Biomedicals." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000630 name: pattern-recognition receptor recognition def: "The process by which a pattern-recognition receptor in the malaria host interprets its surroundings." [IB:IB] synonym: "PRR recognition" EXACT [] is_a: IDOMAL:0000697 ! receptor recognition relationship: part_of GO:0045087 ! innate immune response created_by: guest creation_date: 2009-11-24T10:07:02Z [Term] id: IDOMAL:0000631 name: Malascan Rapid Test for Malaria Pf/Pan (Device) def: "A commercial RDT from Zephyr Biomedicals." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000632 name: Parabank Rapid Test for Malaria Pan (Device) def: "A commercial RDT from Zephyr Biomedicals." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:01:42Z [Term] id: IDOMAL:0000634 name: cotrimoxazole def: "A synthetic antimicrobial drug." [KL:KL] is_a: IDOMAL:0000206 ! sulfonamide created_by: Administrator creation_date: 2008-06-23T08:58:17Z [Term] id: IDOMAL:0000635 name: quality of malaria def: "A quality which refers to malaria." [PT:PT] is_a: IDOMAL:0000002 ! quality created_by: Pantelis creation_date: 2008-08-21T11:00:50Z [Term] id: IDOMAL:0000636 name: ADVANCED QUALITY MALARIA (p.f) POCT def: "A commercial RDT from IntecProducts, Inc." [KL:KL] is_a: IDOMAL:0000340 ! malaria rapid diagnostic test product created_by: louis creation_date: 2010-03-31T12:03:07Z [Term] id: IDOMAL:0000637 name: mosquito bite def: "The insertion of a mosquito's proboscis into the skin of a vertebrate in order to feed with its blood." [KL:KL] is_a: IDOMAL:0000071 ! disruption of body surface is_a: IDOMAL:0002310 ! adult female feeding behaviour relationship: part_of IDOMAL:0002188 ! blood feeding created_by: louis creation_date: 2010-04-09T11:08:44Z [Term] id: IDOMAL:0000638 name: hepatocyte def: "The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules." [CL:0000182] is_a: CL:0000000 ! cell created_by: louis creation_date: 2010-04-09T11:56:24Z [Term] id: IDOMAL:0000639 name: larval stage def: "Any of the four developmental stages immediately following the embryonal stage upon moulting and before pupation." [KL:KL] is_a: IDOMAL:0000612 ! Anopheles developmental stage created_by: louis creation_date: 2010-04-09T01:35:16Z [Term] id: IDOMAL:0000640 name: organism def: "An individual member of a species." [KL:KL] is_a: IDOMAL:0002458 ! anatomical structure created_by: louis creation_date: 2010-04-09T01:45:47Z [Term] id: IDOMAL:0000641 name: CD4-positive, alpha-beta T cell receptor recognition def: "The process by which a CD4-positive, alpha-beta T cell receptor in the malaria host interprets its surroundings." [IB:IB] relationship: part_of IDOMAL:0000620 ! T cell receptor recognition created_by: guest creation_date: 2009-11-24T10:29:59Z [Term] id: IDOMAL:0000642 name: CD8-positive, alpha-beta T cell receptor recognition def: "The process by which a CD8-positive, alpha-beta T cell receptor in the malaria host interprets its surroundings." [IB:IB] relationship: part_of IDOMAL:0000620 ! T cell receptor recognition created_by: guest creation_date: 2009-11-24T10:29:59Z [Term] id: IDOMAL:0000643 name: antibiotic def: "A drug used to treat infections caused by bacteria and other microorganisms." [KL:KL] is_a: IDOMAL:0000001 ! role relationship: has_role IDOMAL:0000258 ! malaria treatment drug created_by: Administrator creation_date: 2008-06-23T09:06:12Z [Term] id: IDOMAL:0000644 name: vector organism def: "An individual member of a vector species." [KL:KL] is_a: IDOMAL:0000640 ! organism created_by: louis creation_date: 2010-04-09T01:47:15Z [Term] id: IDOMAL:0000645 name: parasite organism def: "An individual member of a parasite species." [KL:KL] is_a: IDOMAL:0000640 ! organism created_by: louis creation_date: 2010-04-09T01:47:15Z [Term] id: IDOMAL:0000646 name: embryo def: "A vector organism in its early stages of development, before it has reached the first larval instar stage." [KL:KL] is_a: IDOMAL:0000644 ! vector organism created_by: louis creation_date: 2010-04-09T01:48:51Z [Term] id: IDOMAL:0000647 name: fluoroquinolone def: "Any of a group of broad-spectrum antibiotics that are fluorinated derivatives of quinolone compounds and are especially effective against gram-negative bacteria." [AmericanHeritageMedicalDictionary:0] is_a: IDOMAL:0000672 ! chemical compound relationship: has_role IDOMAL:0000643 ! antibiotic created_by: Administrator creation_date: 2008-06-23T09:07:10Z [Term] id: IDOMAL:0000648 name: immunoglobulin G production def: "The appearance of immunoglobulin G due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [IB:IB] synonym: "IgG production" EXACT [] is_a: GO:0002381 ! immunoglobulin production during immune response created_by: guest creation_date: 2009-12-03T12:16:45Z [Term] id: IDOMAL:0000650 name: immunoglobulin M def: "It is a pentameric gamma globulin protein consisting of five monomers joined by disulfide bonds and the J chain. Each monomer consists of two mu heave chains and either two kappa light chains or two lambda light chains, connected by disulfide bonds." [IB:IB] synonym: "IgM" EXACT [] is_a: IDOMAL:0000764 ! immunoglobulin relationship: participates_in GO:0020013 ! rosetting relationship: participates_in IDOMAL:0000567 ! complement activation, classical pathway created_by: guest creation_date: 2009-12-03T12:49:54Z [Term] id: IDOMAL:0000651 name: toll like receptor recognition def: "The process by which a toll like receptor in the malaria host interprets its surroundings." [IB:IB] synonym: "TLR recognition" EXACT [] is_a: IDOMAL:0000630 ! pattern-recognition receptor recognition created_by: guest creation_date: 2009-11-24T10:43:03Z [Term] id: IDOMAL:0000652 name: toll like receptor 9 recognition def: "The process by which a toll like receptor 9 in the malaria host interprets its surroundings." [IB:IB] synonym: "TLR9 recognition" RELATED [] is_a: IDOMAL:0000651 ! toll like receptor recognition created_by: guest creation_date: 2009-11-24T10:43:38Z [Term] id: IDOMAL:0000653 name: larva def: "The newly hatched, wingless, wormlike form of a vector organism before metamorphosis." [KL:KL] is_a: IDOMAL:0000644 ! vector organism created_by: louis creation_date: 2010-04-09T01:48:51Z [Term] id: IDOMAL:0000654 name: pupa def: "A vector organism during its non-feeding stage between the larva and adult, during which the larva undergoes complete transformation." [KL:KL] is_a: IDOMAL:0000644 ! vector organism created_by: louis creation_date: 2010-04-09T01:48:51Z [Term] id: IDOMAL:0000655 name: adult def: "An vector orgsnid in its sexually mature stage after metamorphosis." [KL:KL] synonym: "imago" EXACT [] is_a: IDOMAL:0000644 ! vector organism created_by: louis creation_date: 2010-04-09T01:48:51Z [Term] id: IDOMAL:0000656 name: first instar larva def: "A vector organism during its first of four larval stages." [KL:KL] is_a: IDOMAL:0000653 ! larva created_by: louis creation_date: 2010-04-09T01:49:27Z [Term] id: IDOMAL:0000657 name: second instar larva def: "A vector organism during its second of four larval stages." [KL:KL] is_a: IDOMAL:0000653 ! larva created_by: louis creation_date: 2010-04-09T01:49:27Z [Term] id: IDOMAL:0000658 name: third instar larva def: "A vector organism during its third of four larval stages." [KL:KL] is_a: IDOMAL:0000653 ! larva created_by: louis creation_date: 2010-04-09T01:49:27Z [Term] id: IDOMAL:0000659 name: fourth instar larva def: "A vector organism during its fourth of four larval stages." [KL:KL] is_a: IDOMAL:0000653 ! larva created_by: louis creation_date: 2010-04-09T01:49:27Z [Term] id: IDOMAL:0000660 name: mosquito gametocyte def: "A gametocyte found in the midgut of a mosquito." [KL:KL] is_a: IDOMAL:0000703 ! gametocyte created_by: louis creation_date: 2010-04-09T01:54:05Z [Term] id: IDOMAL:0000661 name: hemozoin def: "Chemically inert crystalline structure produced in the digestive food vacuole of blood-stage malaria parasites." [ISBN:978-3-540-48994-8] synonym: "beta-hematin" EXACT [] synonym: "malaria pigment" BROAD [] is_a: IDOMAL:0000672 ! chemical compound relationship: participates_in GO:0050765 ! negative regulation of phagocytosis relationship: participates_in IDOMAL:0000652 ! toll like receptor 9 recognition created_by: guest creation_date: 2009-11-24T12:27:59Z [Term] id: IDOMAL:0000662 name: oocyst def: "The encysted form of a parasite organism derived from the ookinete, in which sporogonic multiplication occurs." [KL:KL] is_a: IDOMAL:0000645 ! parasite organism created_by: louis creation_date: 2010-04-09T01:54:05Z [Term] id: IDOMAL:0000663 name: ookinete def: "The motile zygote of the vector organism that penetrates the mosquito midgut to form an oocyst." [KL:KL] is_a: IDOMAL:0000645 ! parasite organism created_by: louis creation_date: 2010-04-09T01:54:05Z [Term] id: IDOMAL:0000664 name: inhibition of hepatocyte invasion def: "To limit or fully inhibiting the extent of parasite invasion of host hepatocytes." [IB:IB] synonym: "inhibition of liver cell invasion" EXACT [] synonym: "inhibition of liver-cell invasion" EXACT [] is_a: IDOMAL:0000601 ! inhibition of invasion created_by: guest creation_date: 2009-11-24T02:19:16Z [Term] id: IDOMAL:0000665 name: aspiration of stomach contents def: "Removal of the stomach's contents via a nasogastric tube." [KL:KL] is_a: IDOMAL:0001283 ! general therapeutic procedure relationship: part_of IDOMAL:0000264 ! ancillary treatment of severe malaria created_by: Administrator creation_date: 2008-06-23T11:08:11Z [Term] id: IDOMAL:0000666 name: inhibition of erythrocyte invasion def: "To limit or fully inhibiting the extent of parasite invasion of host erythrocytes." [IB:IB] synonym: "inhibition of red blood cell invasion" EXACT [] is_a: IDOMAL:0000601 ! inhibition of invasion created_by: guest creation_date: 2009-11-24T02:19:16Z [Term] id: IDOMAL:0000667 name: mosquito control def: "Vector control measures aiming at mosquito populations." [KL:KL] is_a: IDOMAL:0000169 ! malaria vector control relationship: part_of IDOMAL:0000158 ! malaria control created_by: Administrator creation_date: 2008-06-24T11:17:53Z [Term] id: IDOMAL:0000669 name: cytophilic antibody def: "An antibody that attaches to a cell surface through its Fc region." [ISBN:0-8493-1567-0 "Atlas of Immunology"] synonym: "cytophilic isotype" BROAD [] is_a: IDOMAL:0000822 ! antibody created_by: guest creation_date: 2009-11-26T10:13:25Z [Term] id: IDOMAL:0000670 name: zygote def: "A parasite organism at a stage of a diploid cell resulting from the fusion of male and female gametes." [KL:KL] is_a: IDOMAL:0000645 ! parasite organism created_by: louis creation_date: 2010-04-09T01:54:05Z [Term] id: IDOMAL:0000671 name: merozoite stage def: "The stage of a daughter cell of a protozoan parasite. It is formed during schizogony inside the parasitophorous vacuole of a host cell and is equipped with an apical complex in order to enter host cells. Merozoites initiates either another shizogonic process or become gamonts." [IB:IB, ISBN:978-3-540-48994-8] is_a: IDOMAL:0001047 ! vertebrate host stage created_by: guest creation_date: 2009-11-24T02:56:00Z [Term] id: IDOMAL:0000672 name: chemical compound def: "A material with a definite chemical composition." [KL:KL] is_a: IDOMAL:0001034 ! abiotic created_by: Administrator creation_date: 2008-06-24T11:22:24Z [Term] id: IDOMAL:0000673 name: repellent def: "A chemical substance used for repelling insects." [KL:KL] is_a: IDOMAL:0000001 ! role relationship: agent_in IDOMAL:0000608 ! protection against mosquito bites created_by: Administrator creation_date: 2008-06-24T11:22:51Z [Term] id: IDOMAL:0000674 name: selection of habitat def: "The selection of habitat such that the chances of mosquito bites are reduced." [KL:KL] relationship: part_of IDOMAL:0000608 ! protection against mosquito bites created_by: Administrator creation_date: 2008-06-24T11:23:30Z [Term] id: IDOMAL:0000675 name: environmental management def: "The management of interaction by the modern human societies with, and impact upon the environment." [KL:KL] is_a: IDOMAL:0000000 ! process relationship: part_of IDOMAL:0000667 ! mosquito control created_by: Administrator creation_date: 2008-06-24T11:25:01Z [Term] id: IDOMAL:0000676 name: environmental modification def: "In malariology, use of engineering aiming at producing local conditions unfavourable for the breeding of mosquitoes in their usual habitats." [KL:KL] is_a: IDOMAL:0000675 ! environmental management created_by: Administrator creation_date: 2008-06-24T11:25:15Z [Term] id: IDOMAL:0000677 name: filling def: "The filling of abandoned ditches, borrow pits and ponds to remove potential mosquito breeding sites." [KL:KL] is_a: IDOMAL:0000676 ! environmental modification created_by: Administrator creation_date: 2008-06-24T11:28:48Z [Term] id: IDOMAL:0000678 name: drainage def: "Drainage is the natural or artificial removal of surface and sub-surface water from an area." [Wikipedia:newdbxrefdrainage] is_a: IDOMAL:0000676 ! environmental modification created_by: Administrator creation_date: 2008-06-24T11:28:48Z [Term] id: IDOMAL:0000679 name: Lido system def: "In areas of extensive water covered with vegetation where drainage is impractical, the area can be deepened to the extent that plants cannot grow. If the banks of the impoundment are also steepened and stabilised, the introduction of larvivorous fish can reduce mosquito production dramatically." [Health\,NutritionandPopulation(HNP)DiscussionPaper:ISBN1-932126-90-2 "ENVIRONMENTAL MANAGEMENT FOR MALARIA CONTROL IN THE EAST ASIA AND PACIFIC (EAP) REGION"] is_a: IDOMAL:0000677 ! filling created_by: Administrator creation_date: 2008-06-24T11:28:48Z [Term] id: IDOMAL:0000680 name: surface drainage def: "The drainage of the surface." [KL:KL] is_a: IDOMAL:0000678 ! drainage created_by: Administrator creation_date: 2008-06-24T11:36:48Z [Term] id: IDOMAL:0000681 name: subsoil drainage def: "The drainage of subsoil." [KL:KL] synonym: "subsoil drainage" EXACT [] is_a: IDOMAL:0000678 ! drainage created_by: Administrator creation_date: 2008-06-24T11:36:48Z [Term] id: IDOMAL:0000682 name: coastal swamp drainage def: "The drainage of a coastal swamp." [KL:KL] is_a: IDOMAL:0000678 ! drainage created_by: Administrator creation_date: 2008-06-24T11:36:48Z [Term] id: IDOMAL:0000683 name: vertical drainage def: "Drainage of gricultural land by pumped wells to improve the soil." [KL:KL] is_a: IDOMAL:0000678 ! drainage created_by: Administrator creation_date: 2008-06-24T11:36:48Z [Term] id: IDOMAL:0000684 name: environmental manipulation def: "In malariology, a recurrent activity aiming at producing local conditions unfavourable for the breeding of mosquitoes in their usual habitats." [KL:KL] is_a: IDOMAL:0000675 ! environmental management created_by: Administrator creation_date: 2008-06-24T11:38:12Z [Term] id: IDOMAL:0000685 name: human population of non-immune individuals def: "A human population with no immunity against malaria." [KL:KL] relationship: part_of IDOMAL:0001008 ! human population in malarial areas created_by: louis creation_date: 2008-08-06T10:32:58Z [Term] id: IDOMAL:0000686 name: change water levels def: "Deliberate change of the water surface level through engineering or other measures." [KL:KL] is_a: IDOMAL:0000684 ! environmental manipulation created_by: Administrator creation_date: 2008-06-24T11:53:02Z [Term] id: IDOMAL:0000687 name: stream sluicing def: "The use of a water channel that is controlled at its head by a gate." [KL:KL] is_a: IDOMAL:0000684 ! environmental manipulation created_by: Administrator creation_date: 2008-06-24T11:53:02Z [Term] id: IDOMAL:0000688 name: change water salinity def: "Deliberate change of the water salinity through engineering or other measures." [KL:KL] is_a: IDOMAL:0000684 ! environmental manipulation created_by: Administrator creation_date: 2008-06-24T11:53:02Z [Term] id: IDOMAL:0000689 name: shading of stream banks def: "The artificial creation of shaded areas next to stream banks." [KL:KL] is_a: IDOMAL:0000684 ! environmental manipulation created_by: Administrator creation_date: 2008-06-24T11:53:02Z [Term] id: IDOMAL:0000690 name: clearing of vegetation def: "Deliberate clearing of vegetation linked to standing water." [KL:KL] is_a: IDOMAL:0000684 ! environmental manipulation created_by: Administrator creation_date: 2008-06-24T11:53:02Z [Term] id: IDOMAL:0000691 name: blood stage gametocyte def: "A gametocyte found in the blood of the vertebrate host." [KL:KL] is_a: IDOMAL:0000703 ! gametocyte created_by: louis creation_date: 2010-04-09T01:54:05Z [Term] id: IDOMAL:0000692 name: erythrocytic schizont def: "A schizont produced in an erythrocyte." [KL:KL] is_a: IDOMAL:0000706 ! schizont created_by: louis creation_date: 2010-04-09T01:54:05Z [Term] id: IDOMAL:0000693 name: ex-erythrocytic merozoite def: "A merozoite derived from an erythrocytic schizont." [KL:KL] is_a: IDOMAL:0000701 ! merozoite created_by: louis creation_date: 2010-04-09T01:54:05Z [Term] id: IDOMAL:0000694 name: trophozoite def: "The feeding stage of a parasite organism." [KL:KL] is_a: IDOMAL:0000645 ! parasite organism created_by: louis creation_date: 2010-04-09T01:54:05Z [Term] id: IDOMAL:0000696 name: ex-hepatocytic merozoite def: "A merozoite derived from a hepatic schizont." [KL:KL] is_a: IDOMAL:0000701 ! merozoite created_by: louis creation_date: 2010-04-09T01:54:05Z [Term] id: IDOMAL:0000697 name: receptor recognition def: "The process by which a receptor in the malaria host interprets its surroundings." [IB:IB] is_a: IDOMAL:0001054 ! process of malaria host created_by: guest creation_date: 2009-11-30T11:44:23Z [Term] id: IDOMAL:0000698 name: hepatic schizont def: "A schizont produced in an liver cell." [KL:KL] is_a: IDOMAL:0000706 ! schizont created_by: louis creation_date: 2010-04-09T01:54:05Z [Term] id: IDOMAL:0000699 name: hypnozoite def: "An exoerythrocytic schizozoite of Plasmodium vivax or Plasmodium Ovale in the human liver, characterised by delayed primary development and thought to be responsible for malarial relapse." [KL:KL] is_a: IDOMAL:0000645 ! parasite organism created_by: louis creation_date: 2010-04-09T01:54:05Z [Term] id: IDOMAL:0000700 name: sporozoite def: "One of the minute elongated bodies resulting from the repeated division of the oocyst during sporogony." [KL:] is_a: IDOMAL:0000645 ! parasite organism created_by: louis creation_date: 2010-04-09T01:54:05Z [Term] id: IDOMAL:0000701 name: merozoite def: "A vector organism formed during the asexual division of the schizont." [KL:KL] is_a: IDOMAL:0000645 ! parasite organism created_by: louis creation_date: 2010-04-09T01:54:05Z [Term] id: IDOMAL:0000702 name: nitric oxide def: "Nitric oxide is a biological signaling molecule and also one of the principal effector molecules in killing parasites." [IB:IB] synonym: "NO" EXACT [] is_a: IDOMAL:0000672 ! chemical compound relationship: participates_in GO:0006809 ! nitric oxide biosynthetic process created_by: guest creation_date: 2009-11-25T01:50:48Z [Term] id: IDOMAL:0000703 name: gametocyte def: "A parasite organism that has reached the stage of gametocyte." [KL:KL] is_a: IDOMAL:0000645 ! parasite organism created_by: louis creation_date: 2010-04-09T01:55:16Z [Term] id: IDOMAL:0000704 name: sequestration in malaria def: "Is the cytoadherance of parasite infected erythrocytes to vascular endothelium of post-capillary venules in various organs. One of the functions of sequestration is thought to be avoidance of elimination by the spleen." [ISBN:3-8055-7376-6 "Malaria Immunology"] is_a: IDOMAL:0000072 ! pathogen-host interaction relationship: part_of IDOMAL:0000095 ! evasion of host immune response created_by: guest creation_date: 2009-11-25T02:18:56Z [Term] id: IDOMAL:0000706 name: schizont def: "A parasite organism that has been formed from a trophozoite during the asexual stage of the life cycle of sporozoan protozoans, such as the malaria parasite." [KL:KL] is_a: IDOMAL:0000645 ! parasite organism created_by: louis creation_date: 2010-04-09T01:55:16Z [Term] id: IDOMAL:0000707 name: suppression of host immune system def: "Any process by which the pathogen stops, prevents or reduces the frequency, rate or extent of host defence(s)." [IB:IB] synonym: "negative regulation of host defenses" BROAD [] is_a: IDOMAL:0000072 ! pathogen-host interaction relationship: part_of IDOMAL:0000095 ! evasion of host immune response created_by: guest creation_date: 2009-11-25T02:19:24Z [Term] id: IDOMAL:0000708 name: modulation of host immune response def: "Any process by which the pathogen modulates the frequency, rate or extent of host immune response(s)." [IB:IB] relationship: part_of IDOMAL:0000707 ! suppression of host immune system created_by: guest creation_date: 2009-11-25T02:20:11Z [Term] id: IDOMAL:0000709 name: suppression of MHC class II upregulation on dendritic cells and macrophages def: "Any process by which the pathogen stops, prevents or reduces the frequency, rate or extent of MHC class II upregulation on dendritic cells and macrophages." [IB:IB] relationship: part_of IDOMAL:0000707 ! suppression of host immune system created_by: guest creation_date: 2009-11-25T02:22:33Z [Term] id: IDOMAL:0000710 name: suppression of dendritic cell differentiation and maturation def: "Any process by which the pathogen stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation and/or maturation." [IB:IB] synonym: "suppression of DC differentiation and maturation" EXACT [] relationship: part_of IDOMAL:0000707 ! suppression of host immune system created_by: guest creation_date: 2009-11-25T02:22:33Z [Term] id: IDOMAL:0000711 name: condition of malaria vector def: "A condition relating to any species of anopheline vectors of malaria." [KL:KL] is_a: IDOMAL:0001241 ! condition created_by: louis creation_date: 2010-04-09T02:08:54Z [Term] id: IDOMAL:0000729 name: enzyme def: "Any of numerous proteins or conjugated proteins produced by living organisms and functioning as biochemical catalysts." [KL:KL] is_a: IDOMAL:0000001 ! role created_by: guest creation_date: 2009-11-25T09:38:01Z [Term] id: IDOMAL:0000732 name: protein complex def: "It is a group of two or more associated polypeptide chains." [Wikipedia:multiprotein complex] synonym: "multiprotein complex" BROAD [] is_a: IDOMAL:0000611 ! object aggregate created_by: guest creation_date: 2009-11-26T11:51:17Z [Term] id: IDOMAL:0000747 name: T cell mediated immune response def: "An immune response involving a change in the state or activity of a T cell in response to stimulus." [IB:IB] synonym: "T lymphocyte mediated immune response" EXACT [] synonym: "T-cell mediated immune response" EXACT [] synonym: "T-lymphocyte mediated immune response" RELATED [] is_a: IDOMAL:0000022 ! cell mediated immune response relationship: part_of GO:0002250 ! adaptive immune response created_by: guest creation_date: 2009-11-26T01:51:16Z [Term] id: IDOMAL:0000748 name: B cell mediated immune response def: "An immune response involving a change in the state or activity of a B cell in response to stimulus." [IB:IB] synonym: "B lymphocyte mediated immune response" EXACT [] synonym: "B-cell mediated immune response" EXACT [] synonym: "B-lymphocyte mediated immune response" EXACT [] is_a: IDOMAL:0000808 ! humoral immune response relationship: part_of GO:0002250 ! adaptive immune response created_by: guest creation_date: 2009-11-26T01:52:00Z [Term] id: IDOMAL:0000759 name: regulatory T cell mediated immune response def: "An immune response involving a change in the state or activity of a regulatory T cell in response to stimulus." [IB:IB] synonym: "regulatory T lymphocyte mediated immune response" EXACT [] synonym: "regulatory T-cell mediated immune response" EXACT [] synonym: "regulatory T-lymphocyte mediated immune response" EXACT [] is_a: IDOMAL:0000747 ! T cell mediated immune response created_by: guest creation_date: 2009-11-30T10:03:15Z [Term] id: IDOMAL:0000764 name: immunoglobulin def: "Immunoglobulins are gamma globulin proteins consisting of heavy and light chains connected by disulfide bonds. They are synthesized in response to stimulation by an antigen." [IB:IB] synonym: "Ab" RELATED [] synonym: "antibody" RELATED [] synonym: "Ig" EXACT [] is_a: IDOMAL:0001233 ! human host protein created_by: guest creation_date: 2009-11-26T04:34:14Z [Term] id: IDOMAL:0000765 name: immunoglobulin G def: "It is a monomeric gamma globulin protein consisting of two gamma heavy chains and either two kappa light chains or two lambda light chains, connected by disulfide bonds." [IB:IB] synonym: "IgG" EXACT [] is_a: IDOMAL:0000764 ! immunoglobulin relationship: participates_in GO:0020013 ! rosetting relationship: participates_in IDOMAL:0000078 ! antibody-dependent cell-mediated cytotoxic response relationship: participates_in IDOMAL:0000567 ! complement activation, classical pathway relationship: participates_in IDOMAL:0000648 ! immunoglobulin G production created_by: guest creation_date: 2009-11-26T04:35:08Z [Term] id: IDOMAL:0000768 name: cytophilic antibody production def: "The appearance of cytophilic antibodies due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [IB:IB] synonym: "cytophilic Ab production" EXACT [] is_a: GO:0002381 ! immunoglobulin production during immune response relationship: part_of IDOMAL:0000390 ! T-helper 1 cell mediated immune response created_by: guest creation_date: 2009-11-26T04:47:07Z [Term] id: IDOMAL:0000776 name: leukocyte mediated cytotoxic response def: "The direct killing of a target cell by a leukocyte." [IB:IB] synonym: "immune cell mediated cell death" BROAD [] synonym: "immune cell mediated cell killing" BROAD [] synonym: "immune cell mediated cytotoxic response" EXACT [] synonym: "immune cell mediated cytotoxicity" BROAD [] is_a: IDOMAL:0000561 ! host immune effector process created_by: guest creation_date: 2009-11-26T07:59:24Z [Term] id: IDOMAL:0000783 name: tumor necrosis factor-alpha def: "Is a glycoprotein produced by various cells, one being macrophages. Large amounts of tumor necrosis factor-alpha may lead to systemic effects like fever." [ISBN:0-8493-15-67-0] synonym: "cachectin" EXACT [] synonym: "cachexin" EXACT [] synonym: "TNF-alpha" EXACT [] is_a: IDOMAL:0001233 ! human host protein relationship: has_role IDOMAL:0000824 ! cytokine relationship: participates_in GO:0002281 ! macrophage activation during immune response relationship: participates_in IDOMAL:0000790 ! tumor necrosis factor-alpha production created_by: guest creation_date: 2009-11-27T11:00:06Z [Term] id: IDOMAL:0000785 name: toll like receptor 2 recognition def: "The process by which a toll like receptor 2 in the malaria host interprets its surroundings." [IB:IB] synonym: "TLR2 recognition" EXACT [] is_a: IDOMAL:0000651 ! toll like receptor recognition created_by: guest creation_date: 2009-11-28T11:09:38Z [Term] id: IDOMAL:0000786 name: glycosylphosphatidylinositol anchor def: "They are glycolipids with the major function of anchoring proteins to cell membrane surfaces. They are particularly abundant in protozoan parasites, where they serve as the predominant mechanism for integrating glycoproteins and phosphosaccharides into membrane lipid bilayers." [ISBN:978-3-540-48994-8] synonym: "GPI anchor" EXACT [] synonym: "GPI-anchor" EXACT [] is_a: IDOMAL:0001233 ! human host protein relationship: participates_in IDOMAL:0000785 ! toll like receptor 2 recognition created_by: guest creation_date: 2009-11-28T11:11:03Z [Term] id: IDOMAL:0000788 name: interferon-gamma production def: "The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [IB:IB] synonym: "IFN-gamma production" EXACT [] is_a: GO:0002367 ! cytokine production during immune response relationship: part_of IDOMAL:0000392 ! natural killer cell mediated cytotoxic response created_by: guest creation_date: 2009-11-28T12:35:56Z [Term] id: IDOMAL:0000790 name: tumor necrosis factor-alpha production def: "The appearance of tumor necrosis factor-alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [IB:IB] synonym: "TNF-alpha production" EXACT [] is_a: GO:0002367 ! cytokine production during immune response relationship: part_of GO:0045087 ! innate immune response created_by: guest creation_date: 2009-11-30T10:30:52Z [Term] id: IDOMAL:0000793 name: antibody-independent opsonization def: "The process by which a microorganism (or other particulate material) is rendered more susceptible to phagocytosis by coating with an opsonin, a blood serum protein such as a complement." [IB:IB] is_a: GO:0008228 ! opsonization relationship: part_of IDOMAL:0000124 ! phagocytosis during innate immune response created_by: guest creation_date: 2009-11-30T01:50:41Z [Term] id: IDOMAL:0000795 name: complement activation, alternative pathway def: "Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for opsonization or direct killing of pathogens." [IB:IB] is_a: IDOMAL:0000810 ! complement activation relationship: part_of IDOMAL:0000793 ! antibody-independent opsonization created_by: guest creation_date: 2009-11-30T01:52:51Z [Term] id: IDOMAL:0000799 name: suppression of T cell activation def: "Any process by which the pathogen stops, prevents or reduces the frequency, rate or extent of T cell activation." [IB:IB] synonym: "suppression of T lymphocyte activation" EXACT [] synonym: "suppression of T-cell activation" EXACT [] synonym: "suppression of T-lymphocyte activation" EXACT [] relationship: part_of IDOMAL:0000707 ! suppression of host immune system created_by: guest creation_date: 2009-11-30T02:48:12Z [Term] id: IDOMAL:0000804 name: host metabolic process def: "The chemical reactions and pathways, including anabolism and catabolism, by which the host transforms chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation." [IB:IB] synonym: " host metabolism" BROAD [] is_a: IDOMAL:0001054 ! process of malaria host created_by: guest creation_date: 2009-11-30T05:39:02Z [Term] id: IDOMAL:0000808 name: humoral immune response def: "An immune response mediated through a body fluid." [GO:0006959] is_a: IDOMAL:0000006 ! host immune response created_by: guest creation_date: 2009-12-01T09:48:32Z [Term] id: IDOMAL:0000810 name: complement activation def: "Any process involved in the activation of any of the steps of the alternative pathway or classical pathway of the complement cascade, which allows for opsonization or direct killing of pathogens." [IB:IB] is_a: IDOMAL:0000561 ! host immune effector process created_by: guest creation_date: 2009-12-01T02:47:12Z [Term] id: IDOMAL:0000811 name: T-helper 1 cell mediated cytokine production def: "The appearance of cytokines part of the T-helper 1 cell mediated response, due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [IB:IB] synonym: "Th1 cell mediated cytokine production" EXACT [] is_a: GO:0002367 ! cytokine production during immune response relationship: part_of IDOMAL:0000390 ! T-helper 1 cell mediated immune response created_by: guest creation_date: 2009-12-02T10:37:57Z [Term] id: IDOMAL:0000812 name: T-helper 2 cell mediated cytokine production def: "The appearance of cytokines part of the T-helper 2 cell mediated response, due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [IB:IB] synonym: "Th2 cell mediated cytokine production" EXACT [] is_a: GO:0002367 ! cytokine production during immune response relationship: part_of IDOMAL:0000391 ! T-helper 2 cell mediated immune response created_by: guest creation_date: 2009-12-02T10:41:38Z [Term] id: IDOMAL:0000816 name: activation-induced cell death def: "It is the process by which cells undergo apoptosis in a controlled manner through the interaction of a death factor and its receptor. It plays a significant role in immune system homeostasis." [PMID:11940113 "Bouchier-Hayes D."] synonym: "AICD" EXACT [] is_a: GO:0008219 ! cell death created_by: guest creation_date: 2009-12-08T09:48:03Z [Term] id: IDOMAL:0000822 name: antibody def: "A immunoglobulin protein that is secreted into the blood or lymph in response to an antigenic stimulus, such as a bacterium, virus, parasite, or transplanted organ, and that neutralizes the antigen by binding specifically to it." [KL:KL] is_a: IDOMAL:0000001 ! role created_by: guest creation_date: 2009-12-02T04:59:07Z [Term] id: IDOMAL:0000824 name: cytokine def: "Cytokines serve as chemical communicators from one cell to another as well as being biological response modifiers." [ISBN:0-8493-1567-0] is_a: IDOMAL:0000001 ! role created_by: guest creation_date: 2009-12-02T08:41:21Z [Term] id: IDOMAL:0000862 name: insecticide synergist def: "A chemical substance that improves the efficacy ofd an insecticide." [KL:KL] is_a: IDOMAL:0000001 ! role [Term] id: IDOMAL:0000873 name: piperonyl butoxide def: "A substance acting as an insecticide synergist." [KL:KL] synonym: "5-[2-(2-butoxyethoxy)ethoxymethyl]-6-propyl-1,3-benzodioxole" EXACT [] synonym: "PBO" EXACT [] is_a: IDOMAL:0000672 ! chemical compound relationship: has_role IDOMAL:0000862 ! insecticide synergist [Term] id: IDOMAL:0000878 name: DEF def: "A substance often used as a synergist for insecticides." [KL:KL "MIRO: 10000187"] synonym: "S,S,S-tributyl phosphorotrithioate" EXACT [] is_a: IDOMAL:0000672 ! chemical compound relationship: has_role IDOMAL:0000862 ! insecticide synergist [Term] id: IDOMAL:0000880 name: sesamex def: "A substance acting as an insecticide synergist." [KL:KL] synonym: "(RS)-5-{1-[2-(2-ethoxyethoxy)ethoxy]ethoxy}-1,3-benzodioxole" EXACT [] is_a: IDOMAL:0000672 ! chemical compound relationship: has_role IDOMAL:0000862 ! insecticide synergist [Term] id: IDOMAL:0000883 name: SV1 def: "A chemical substance that acts as an insecticide synergist." [KL:KL] synonym: "O,O-diethyl O-phenyl phosphorothioate" EXACT [] synonym: "SV-1" EXACT [] is_a: IDOMAL:0000672 ! chemical compound relationship: has_role IDOMAL:0000862 ! insecticide synergist [Term] id: IDOMAL:0000886 name: triphenyl phosphate def: "A chemical substance that acts as an insecticide synergist." [KL:KL] synonym: "TPP" EXACT [] is_a: IDOMAL:0000672 ! chemical compound relationship: has_role IDOMAL:0000862 ! insecticide synergist [Term] id: IDOMAL:0000888 name: piprotal def: "A substance acting as an insecticide synergist." [KL:KL] synonym: "5-{bis[2-(2-butoxyethoxy)ethoxy]methyl}-1,3-benzodioxole" EXACT [] is_a: IDOMAL:0000672 ! chemical compound relationship: has_role IDOMAL:0000862 ! insecticide synergist [Term] id: IDOMAL:0000891 name: propyl isome def: "A substance acting as an insecticide synergist." [KL:KL] synonym: "dipropyl 5,6,7,8-tetrahydro-7-methylnaphtho[2,3-d]-1,3-dioxole-5,6-dicarboxylate" EXACT [] is_a: IDOMAL:0000672 ! chemical compound relationship: has_role IDOMAL:0000862 ! insecticide synergist [Term] id: IDOMAL:0000893 name: sesamolin def: "Sesamol is a natural organic compound which is a component of sesame oil." [KL:KL] synonym: "1,3-benzodioxol-5-yl (1R,3aR,4S,6aR)-4-(1,3-benzodioxol-5-yl)perhydrofuro[3,4-c]furan-1-yl ether" EXACT [] is_a: IDOMAL:0000672 ! chemical compound relationship: has_role IDOMAL:0000862 ! insecticide synergist [Term] id: IDOMAL:0000895 name: sulfoxide def: "The sulphur analog of a ketone that can have the role of an insecticide synergist." [KL:KL] synonym: "(RS)-2-(1,3-benzodioxol-5-yl)-1-methylethyl octyl sulfoxide" EXACT [] is_a: IDOMAL:0000672 ! chemical compound relationship: has_role IDOMAL:0000862 ! insecticide synergist [Term] id: IDOMAL:0000898 name: tribufos def: "A chemical substance that acts as an insecticide synergist." [KL:KL] synonym: "S,S,S-tributyl phosphorotrithioate" RELATED [] is_a: IDOMAL:0000672 ! chemical compound relationship: has_role IDOMAL:0000862 ! insecticide synergist [Term] id: IDOMAL:0000900 name: biological mosquito control def: "A method of mosquito control based on the introduction into the environment of various pathogens and predators of insect disease vectors." [KL:KL] relationship: part_of IDOMAL:0000667 ! mosquito control created_by: Administrator creation_date: 2008-06-24T07:20:38Z [Term] id: IDOMAL:0000902 name: introduction of predators of mosquito vectors def: "A method of mosquito control based on the introduction into the environment of various predators of insect disease vectors." [KL:KL] is_a: IDOMAL:0000900 ! biological mosquito control created_by: Administrator creation_date: 2008-06-24T07:21:48Z [Term] id: IDOMAL:0000905 name: introduction of B. israelensis def: "The usage of B. israelensis in a potential vector breeding site/habitat to achieve reduction or elimination of a vector population." [KL:KL] is_a: IDOMAL:0001022 ! usage of bacterial pathogens created_by: Administrator creation_date: 2008-06-24T07:26:13Z [Term] id: IDOMAL:0000907 name: introduction of B. sphaericus def: "The usage of B. sphaericus in a potential vector breeding site/habitat to achieve reduction or elimination of a vector population." [KL:KL] is_a: IDOMAL:0001022 ! usage of bacterial pathogens created_by: Administrator creation_date: 2008-06-24T07:26:13Z [Term] id: IDOMAL:0000909 name: introduction of Coelomyces def: "The usage of Coelomyces in a potential vector breeding site/habitat to achieve reduction or elimination of a vector population." [KL:KL] is_a: IDOMAL:0001023 ! usage of fungal pathogens created_by: Administrator creation_date: 2008-06-24T07:26:13Z [Term] id: IDOMAL:0000911 name: introduction of Culicinomyces def: "The usage of Culicinomyces in a potential vector breeding site/habitat to achieve reduction or elimination of a vector population." [KL:KL] is_a: IDOMAL:0001023 ! usage of fungal pathogens created_by: Administrator creation_date: 2008-06-24T07:26:13Z [Term] id: IDOMAL:0000913 name: introduction of Lagenidium def: "The usage of Lagenidium in a potential vector breeding site/habitat to achieve reduction or elimination of a vector population." [KL:KL] is_a: IDOMAL:0001023 ! usage of fungal pathogens created_by: Administrator creation_date: 2008-06-24T07:26:13Z [Term] id: IDOMAL:0000916 name: introduction of Romanomermis culicivorax def: "A method of mosquito control based on the introduction into the environment of a nematode that parasitizes mosquito larvae. ." [KL:KL] is_a: IDOMAL:0000902 ! introduction of predators of mosquito vectors created_by: Administrator creation_date: 2008-06-24T07:26:13Z [Term] id: IDOMAL:0000918 name: introduction of larvivorous fish def: "A method of mosquito control based on the introduction into the environment of larvivorous fish." [KL:KL] is_a: IDOMAL:0000902 ! introduction of predators of mosquito vectors created_by: Administrator creation_date: 2008-06-24T07:26:13Z [Term] id: IDOMAL:0000923 name: zooprophylaxis def: "The deliberate diversion of vectors to animal hosts, mostly in rural areas, to keep humans from being bitten by infected mosquitoes." [KL:KL] relationship: part_of IDOMAL:0000158 ! malaria control created_by: Administrator creation_date: 2008-06-24T07:27:15Z [Term] id: IDOMAL:0000930 name: insecticidal substance def: "A chemical substance used for killing insects." [KL:KL] xref: IRAC:eClassification "http://www.irac-online.org/eClassification/" is_a: IDOMAL:0000672 ! chemical compound relationship: agent_in IDOMAL:0000429 ! usage of insecticides [Term] id: IDOMAL:0000954 name: process of malaria host population def: "A process relating to a population of malaria hosts." [KL:KL] is_a: IDOMAL:0000000 ! process created_by: Administrator creation_date: 2008-06-24T10:55:18Z [Term] id: IDOMAL:0000959 name: process of malaria def: "A process relating to malaria." [KL:KL] is_a: IDOMAL:0000000 ! process created_by: Administrator creation_date: 2008-06-24T10:55:18Z [Term] id: IDOMAL:0000963 name: rodent def: "A species belonging to the mammalian order Rodentia." [KL:KL] is_a: IDOMAL:0000605 ! mammal created_by: louis creation_date: 2008-07-30T10:28:45Z [Term] id: IDOMAL:0000980 name: bird def: "A vertebrate animal of the class Aves." [KL:KL] is_a: IDOMAL:0001274 ! vertebrate created_by: louis creation_date: 2008-07-30T10:29:18Z [Term] id: IDOMAL:0000982 name: reptile def: "Reptiles, or members of the class Reptilia, are air-breathing, cold-blooded amniotes that have skin covered in scales or scutes as opposed to hair or feathers." [Wikipedia:reptile] is_a: IDOMAL:0001274 ! vertebrate created_by: louis creation_date: 2008-07-30T10:29:49Z [Term] id: IDOMAL:0000984 name: lemurs def: "Any species belonging to the genus Lemur." [KL:KL] is_a: IDOMAL:0000606 ! primate created_by: louis creation_date: 2008-07-30T10:31:44Z [Term] id: IDOMAL:0000990 name: buffalo def: "Any of various wild oxen, sometimes domesticated, as the water buffalo of India or Cape buffalo of Africa." [YourDictionary.com:Buffalo] is_a: IDOMAL:0000605 ! mammal created_by: louis creation_date: 2008-07-30T10:31:44Z [Term] id: IDOMAL:0000991 name: deer def: "Any of a family (Cervidae) of ruminants, including the elk, moose, and reindeer." [yourDictionary.com:Deer] is_a: IDOMAL:0000605 ! mammal created_by: louis creation_date: 2008-07-30T10:31:44Z [Term] id: IDOMAL:0000992 name: squirrel def: "Any species in the family Sciuridae." [KL:KL] is_a: IDOMAL:0000963 ! rodent created_by: louis creation_date: 2008-07-30T10:32:12Z [Term] id: IDOMAL:0000993 name: bat def: "Any species in the order Chiroptera." [KL:KL] is_a: IDOMAL:0000963 ! rodent created_by: louis creation_date: 2008-07-30T10:32:12Z [Term] id: IDOMAL:0000995 name: parasite def: "A symbiont role borne by an organism in virtue of the fact that it derives a growth, survival, or fitness advantage from symbiosis while the other symbiont's growth, survival, or fitness is reduced." [IDO:443] is_a: IDOMAL:0000001 ! role created_by: louis creation_date: 2008-07-30T11:08:03Z [Term] id: IDOMAL:0001004 name: Plasmodium penetration of invertebrate host def: "The process of entry of a Plasmodium parasite into an invertebrate host cell." [KL:KL] is_a: IDOMAL:0000084 ! Plasmodium penetration of host cell created_by: louis creation_date: 2008-07-30T12:00:54Z [Term] id: IDOMAL:0001006 name: Plasmodium penetration of vertebrate host def: "The process of entry of a Plasmodium parasite into a vertebrate host cell." [KL:KL] is_a: IDOMAL:0000084 ! Plasmodium penetration of host cell created_by: louis creation_date: 2008-07-30T12:00:54Z [Term] id: IDOMAL:0001008 name: human population in malarial areas def: "A collection of human individuals in an area in which malaria is endemic." [KL:KL] is_a: IDOMAL:0001255 ! human population created_by: louis creation_date: 2008-07-30T12:34:12Z [Term] id: IDOMAL:0001009 name: human population in non malarial areas def: "A collection of human individuals in an area in which malaria is not endemic." [KL:KL] is_a: IDOMAL:0001255 ! human population created_by: louis creation_date: 2008-07-30T12:34:12Z [Term] id: IDOMAL:0001010 name: accidental transmission def: "Malaria transmission through transfer of infected blood into a patient by accident." [KL:KL] is_a: IDOMAL:0000188 ! iatrogenic transmission created_by: louis creation_date: 2008-07-30T12:44:46Z [Term] id: IDOMAL:0001011 name: blood transfusion def: "The process of transferring blood or blood-based products from one person into the circulatory system of another." [Wikipedia:bloodtransfusion] is_a: IDOMAL:0001283 ! general therapeutic procedure relationship: realizes IDOMAL:0001010 ! accidental transmission created_by: louis creation_date: 2008-07-30T12:45:11Z [Term] id: IDOMAL:0001012 name: hepatocyte invasion def: "The invasion of hepatocytes by sporozoites upon entry in the bloodstream of the host." [KL:KL] is_a: IDOMAL:0001006 ! Plasmodium penetration of vertebrate host relationship: part_of IDOMAL:0000475 ! pre-erythrocytic schizogony created_by: louis creation_date: 2008-07-30T12:52:22Z [Term] id: IDOMAL:0001013 name: quality of vector def: "A quality which refers to vectors." [PT:PT] is_a: IDOMAL:0000002 ! quality created_by: louis creation_date: 2008-07-30T01:09:26Z [Term] id: IDOMAL:0001014 name: quality of vector population def: "A quality which refers to vector population." [PT:PT] is_a: IDOMAL:0000002 ! quality created_by: louis creation_date: 2008-07-30T01:09:26Z [Term] id: IDOMAL:0001015 name: relapse def: "The return of P. vivax or P. ovale malaria after its apparent cessation, occuring weeks or months after the primary infection." [KL:KL] synonym: "dormancy " RELATED [] relationship: part_of IDOMAL:0001053 ! occurrence of malaria created_by: louis creation_date: 2008-07-30T01:19:14Z [Term] id: IDOMAL:0001016 name: recrudescence def: "The recurrence of symptoms of P. falciparum malaria some days or weeks after a temporary abatement." [KL:KL] relationship: part_of IDOMAL:0001053 ! occurrence of malaria created_by: louis creation_date: 2008-07-30T01:19:14Z [Term] id: IDOMAL:0001018 name: human population of immune individuals def: "A human population with acquired partial or full immunity against malaria." [KL:KL] relationship: part_of IDOMAL:0001008 ! human population in malarial areas created_by: louis creation_date: 2008-08-06T10:32:58Z [Term] id: IDOMAL:0001019 name: mouse def: "A mouse is a small mammal belonging to the genus Mus." [KL:KL] is_a: IDOMAL:0000963 ! rodent created_by: louis creation_date: 2008-08-06T10:45:49Z [Term] id: IDOMAL:0001020 name: usage of mosquito pathogens def: "The usage of different pathogens of mosquitos, usually for the purpose of mosquito control." [KL:KL] is_a: IDOMAL:0000900 ! biological mosquito control created_by: louis creation_date: 2008-08-06T11:23:51Z [Term] id: IDOMAL:0001021 name: introduction of B. thurigiensis def: "The usage of B. thurigiensis in a potential vector breeding site/habitat to achieve reduction or elimination of a vector population." [KL:KL] is_a: IDOMAL:0001022 ! usage of bacterial pathogens created_by: louis creation_date: 2008-08-06T11:24:35Z [Term] id: IDOMAL:0001022 name: usage of bacterial pathogens def: "The usage of bacterial pathogens of mosquitos, usually for the purpose of mosquito control." [KL:KL] is_a: IDOMAL:0001020 ! usage of mosquito pathogens created_by: louis creation_date: 2008-08-06T11:27:18Z [Term] id: IDOMAL:0001023 name: usage of fungal pathogens def: "The usage of fungal pathogens of mosquitos, usually for the purpose of mosquito control." [KL:KL] is_a: IDOMAL:0001020 ! usage of mosquito pathogens created_by: louis creation_date: 2008-08-06T11:27:18Z [Term] id: IDOMAL:0001024 name: screening material def: "Wire or cloth mesh used to prevent insects from entering a building or landing on a potential food source." [KL:KL] is_a: IDOMAL:0001034 ! abiotic relationship: agent_in IDOMAL:0000608 ! protection against mosquito bites created_by: louis creation_date: 2008-08-06T11:56:41Z [Term] id: IDOMAL:0001025 name: frame screen def: "A mesh screen blocking entry of insecticides through an opening." [KL:KL] is_a: IDOMAL:0001024 ! screening material created_by: louis creation_date: 2008-08-06T11:58:28Z [Term] id: IDOMAL:0001026 name: bednet def: "Netting hung over a bed to keep out mosquitos and other insects." [KL:KL] is_a: IDOMAL:0001024 ! screening material created_by: louis creation_date: 2008-08-06T11:58:28Z [Term] id: IDOMAL:0001027 name: door screen def: "A screen preventing insects from crossing an open door." [KL:KL] is_a: IDOMAL:0001025 ! frame screen created_by: louis creation_date: 2008-08-06T12:00:53Z [Term] id: IDOMAL:0001028 name: window screen def: "A screen preventing insects from crossing an open window." [KL:KL] is_a: IDOMAL:0001025 ! frame screen created_by: louis creation_date: 2008-08-06T12:00:53Z [Term] id: IDOMAL:0001029 name: porch screen def: "A screen preventing insects from arriving at a porch." [KL:KL] is_a: IDOMAL:0001025 ! frame screen created_by: louis creation_date: 2008-08-06T12:00:53Z [Term] id: IDOMAL:0001030 name: untreated net def: "A bednet that has not been treated with insecticides." [KL:KL] is_a: IDOMAL:0001026 ! bednet created_by: louis creation_date: 2008-08-06T12:02:45Z [Term] id: IDOMAL:0001031 name: protective clothing def: "Clothes worn in order to prevent mosquitoes from biting." [KL:KL] is_a: IDOMAL:0001034 ! abiotic relationship: agent_in IDOMAL:0000608 ! protection against mosquito bites created_by: louis creation_date: 2008-08-06T12:03:44Z [Term] id: IDOMAL:0001032 name: sporadic malaria def: "A case of malaria occurring, sporadically, in areas wjere malaria is not endemic." [KL:KL] is_a: IDOMAL:0000029 ! epidemiological type of malaria created_by: louis creation_date: 2008-08-06T12:36:33Z [Term] id: IDOMAL:0001033 name: mechanism of refractoriness def: "A molecular mechanism that renders a vector organism refractory to effectively hosting a vector." [KL:KL] is_a: IDOMAL:0001059 ! process of malaria vector relationship: realizes IDOMAL:0000350 ! refractoriness created_by: Pantelis creation_date: 2008-08-21T11:09:12Z [Term] id: IDOMAL:0001034 name: abiotic def: "A non-living object." [KL:KL] is_a: IDOMAL:0000003 ! object created_by: louis creation_date: 2008-09-09T10:48:10Z [Term] id: IDOMAL:0001037 name: process of malaria epidemiology def: "The epidemiological analysis of malaria." [KL:KL] is_a: IDOMAL:0000959 ! process of malaria created_by: louis creation_date: 2008-09-09T11:05:29Z [Term] id: IDOMAL:0001038 name: usage of repellent def: "Use of chemical repellent to keep vectors far from humans." [KL:KL] is_a: IDOMAL:0000312 ! use of chemicals created_by: louis creation_date: 2008-09-09T11:28:19Z [Term] id: IDOMAL:0001039 name: immunization def: "A process by which an organism acquires immunity to an infectious agent." [IDO:497] synonym: "immunisation" EXACT [] is_a: IDOMAL:0001054 ! process of malaria host created_by: louis creation_date: 2008-09-09T11:50:01Z [Term] id: IDOMAL:0001040 name: vaccination def: "The administration of antigenic material (the vaccine) to produce immunity to a disease." [Wikipedia:vaccination] is_a: IDOMAL:0001039 ! immunization created_by: louis creation_date: 2008-09-09T11:50:24Z [Term] id: IDOMAL:0001041 name: zoophily def: "The preference for feeding on animals." [ISBN:034057190X "Essential Malariology"] is_a: IDOMAL:0001013 ! quality of vector created_by: louis creation_date: 2008-09-09T01:14:02Z [Term] id: IDOMAL:0001042 name: anthropophily def: "The preference for feeding on humans." [ISBN:034057190X "Essential Malariology"] is_a: IDOMAL:0001013 ! quality of vector created_by: louis creation_date: 2008-09-09T01:14:02Z [Term] id: IDOMAL:0001043 name: endophily def: "The habit of remaining within a man-made shelter throughout the whole or a definite part of the gonotrophic cycle." [ISBN:034057190X "Essential Malariology"] is_a: IDOMAL:0001013 ! quality of vector created_by: louis creation_date: 2008-09-09T01:14:02Z [Term] id: IDOMAL:0001044 name: exophily def: "The habit of spending the greater part of the gonotrophic cycle out of doors." [ISBN:034057190X "Essential Malariology"] is_a: IDOMAL:0001013 ! quality of vector created_by: louis creation_date: 2008-09-09T01:14:02Z [Term] id: IDOMAL:0001045 name: endophagy def: "The habit of obtaining the blood meal within a man-made structure." [ISBN:034057190X "Essential Malariology"] is_a: IDOMAL:0001013 ! quality of vector created_by: Pantelis creation_date: 2008-09-10T09:49:59Z [Term] id: IDOMAL:0001046 name: exophagy def: "The habit of seeking the blood meal out of doors." [ISBN:034057190X "Essential Malariology"] is_a: IDOMAL:0001013 ! quality of vector created_by: Pantelis creation_date: 2008-09-10T09:49:59Z [Term] id: IDOMAL:0001047 name: vertebrate host stage def: "Any life cycle stage of Plasmodium that is spent in the vertebrate host." [PT:PT] is_a: IDOMAL:0000296 ! Plasmodium parasite stage created_by: Pantelis creation_date: 2008-09-11T10:27:21Z [Term] id: IDOMAL:0001048 name: susceptibility def: "A quality that inheres in an entity and is the degree to which it can be harmed by another entity of a certain type." [IDO:467] is_a: IDOMAL:0001013 ! quality of vector created_by: Pantelis creation_date: 2008-09-11T10:46:55Z [Term] id: IDOMAL:0001050 name: disposition def: "A realizable dependent continuant that typically causes a specific process in the object in which it inheres when the object is introduced into certain specific circumstances." [NaturePrecedings:hdl\:10101/npre.2008.1941.1 "Function, Role, and Disposition in Basic Formal Ontology"] created_by: Pantelis creation_date: 2008-12-22T08:44:20Z [Term] id: IDOMAL:0001051 name: infectious disease def: "A disease whose physical basis is an infection." [IDO:436] is_a: IDOMAL:0001050 ! disposition created_by: Pantelis creation_date: 2008-12-22T08:45:03Z [Term] id: IDOMAL:0001052 name: malaria def: "An acute febrile illness characterized by periodic febrile paroxysms caused by parasites of the genus Plasmodium." [KL:KL] is_a: IDOMAL:0001051 ! infectious disease created_by: Pantelis creation_date: 2008-12-22T08:45:26Z [Term] id: IDOMAL:0001053 name: occurrence of malaria def: "Any case of malaria occurring." [KL:KL] is_a: IDOMAL:0000959 ! process of malaria relationship: realizes IDOMAL:0001052 ! malaria created_by: Pantelis creation_date: 2008-12-22T08:52:38Z [Term] id: IDOMAL:0001054 name: process of malaria host def: "A process relating to a malaria host." [KL:KL] is_a: IDOMAL:0000000 ! process created_by: Pantelis creation_date: 2009-01-07T08:35:37Z [Term] id: IDOMAL:0001055 name: malaria vaccine def: "A vaccine against malaria." [KL:KL] is_a: IDOMAL:0000262 ! vaccine relationship: agent_in IDOMAL:0000021 ! malaria vaccination created_by: Pantelis creation_date: 2009-01-07T08:39:47Z [Term] id: IDOMAL:0001058 name: process of malaria pathogen def: "A process relating to a malaria pathogen." [KL:KL] is_a: IDOMAL:0000000 ! process created_by: Pantelis creation_date: 2009-01-07T08:43:29Z [Term] id: IDOMAL:0001059 name: process of malaria vector def: "A process relating to a malaria vector." [KL:KL] is_a: IDOMAL:0000000 ! process created_by: Pantelis creation_date: 2009-01-07T08:44:37Z [Term] id: IDOMAL:0001060 name: process of malaria vector population def: "A process relating to a population of malaria vectors." [KL:KL] is_a: IDOMAL:0000000 ! process created_by: Pantelis creation_date: 2009-01-07T08:45:19Z [Term] id: IDOMAL:0001061 name: malaria vector def: "An anopheline mosquito transmitting malaria." [KL:KL] is_a: IDOMAL:0000001 ! role created_by: Pantelis creation_date: 2009-01-07T08:52:38Z [Term] id: IDOMAL:0001062 name: malaria host def: "The host of (a) malaria parasite(s)." [KL:KL] is_a: IDOMAL:0000055 ! host created_by: Pantelis creation_date: 2009-01-07T08:56:55Z [Term] id: IDOMAL:0001065 name: human malaria parasite def: "A malaria parasite naturally infecting humans and using them as a reservoir for disease." [KL:KL] is_a: IDOMAL:0001286 ! malaria parasite created_by: Pantelis creation_date: 2009-01-07T08:59:01Z [Term] id: IDOMAL:0001066 name: malaria pathogen is_obsolete: true created_by: Pantelis creation_date: 2009-01-07T08:59:23Z [Term] id: IDOMAL:0001067 name: protein def: "A natural macromolecule with aminoacids as basic components connected to each other through peptide bonds." [KL:KL] is_a: IDOMAL:0000672 ! chemical compound created_by: Pantelis creation_date: 2009-05-10T07:43:54Z [Term] id: IDOMAL:0001068 name: host protein def: "A protein that is produced by a host." [KL:KL] is_a: IDOMAL:0001067 ! protein created_by: Pantelis creation_date: 2009-05-10T07:45:00Z [Term] id: IDOMAL:0001069 name: Plasmodium parasite protein def: "A protein that is naturally found in Plasmodium parasites." [KL:KL] is_a: IDOMAL:0001067 ! protein created_by: Pantelis creation_date: 2009-05-10T07:45:00Z [Term] id: IDOMAL:0001070 name: vector protein def: "A protein that is naturally found in disease vectors." [KL:KL] is_a: IDOMAL:0001067 ! protein created_by: Pantelis creation_date: 2009-05-10T07:45:00Z [Term] id: IDOMAL:0001071 name: P25 def: "A surface protein expressed in the of the ookinete which interacts with calreticulin on the midgut apical surface of the malaria vector." [PMID:17442413 "The surface protein Pvs25 of Plasmodium vivax ookinetes interacts with calreticulin on the midgut apical surface of the malaria vector Anopheles albimanus.", PMID:4039406 "Biosynthesis of two stage-specific membrane proteins during transformation of Plasmodium gallinaceum zygotes into ookinetes."] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000185 ! invasion of mosquito midgut epithelium created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001072 name: P28 def: "A ookinete surface protein which interacts with laminin gamma1 present in mosquito midgut basal lamina." [PMID:2440053 "Ookinete antigens of Plasmodium berghei: a light and electron-microscope immunogold study of expression of the 21 kDa determinant recognized by a transmission-blocking antibody."] synonym: "Pbs-21" EXACT [PMID:2440053 "Ookinete antigens of Plasmodium berghei: a light and electron-microscope immunogold study of expression of the 21 kDa determinant recognized by a transmission-blocking antibody."] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000185 ! invasion of mosquito midgut epithelium created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001073 name: SOAP def: "A soluble protein that is expressed and secreted by ookinetes via micronemes." [PMID:12828632 "SOAP, a novel malaria ookinete protein involved in mosquito midgut invasion and oocyst development."] synonym: "secreted ookinete adhesive protein" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000185 ! invasion of mosquito midgut epithelium created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001074 name: CTRP def: "A transmembrane protein expressed in ookinete micronemes." [PMID:10562534 "CTRP is essential for mosquito infection by malaria ookinetes."] synonym: "circumsporozoite and TRAP related protein" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001075 name: WARP def: "A micronemal, ookinete, small secreted soluble protein which forms high molecular mass complexes via disulphide bonds." [PMID:11463467 "von Willebrand Factor A domain-related protein, a novel microneme protein of the malaria ookinete highly conserved throughout Plasmodium parasites."] synonym: "von Willebrand Factor A domain related protein" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001076 name: PbCHT1 def: "A protein with the ability to hydrolyze chitin." [PMID:11349074 "Knockout of the rodent malaria parasite chitinase pbCHT1 reduces infectivity to mosquitoes."] synonym: "chitinase" BROAD [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000173 ! traversion of peritrophic membrane created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001077 name: celTOS def: "A micronemal protein." [PMID:16468982 "CelTOS, a novel malarial protein that mediates transmission to mosquito and vertebrate hosts."] synonym: "cell traversal protein for ookinetes and sporozoites" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001078 name: CDPK3 def: "A protein expressed in ookinetes required to cross the layer between blood meal and the midgut epithelium." [PMID:16430692 "A calcium-dependent protein kinase regulates Plasmodium ookinete access to the midgut epithelial cell."] synonym: "calcium dependent protein kinase 3" RELATED [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001079 name: PbGC beta guanylate cyclase def: "A single molecule with a guanylate cyclase domain and N-terminal P-type ATPase like domain." [PMID:17030505 "PbGCbeta is essential for Plasmodium ookinete motility to invade midgut cell and for successful completion of parasite life cycle in mosquitoes."] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001080 name: MAOP def: "A micronemal protein with a membrane attack complex and perforin-related domain." [PMID:15520375 "Essential role of membrane-attack protein in malarial transmission to mosquito host."] synonym: "Membrane attack protein" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000185 ! invasion of mosquito midgut epithelium created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001081 name: calreticulin def: "A protein found on mosquito salivary glands and on midgut microvilli." [PMID:12124367 "Toward a catalog for the transcripts and proteins (sialome) from the salivary gland of the malaria vector Anopheles gambiae.", PMID:15733320 "Do malaria ookinete surface proteins P25 and P28 mediate parasite entry into mosquito midgut epithelial cells?", PMID:17442413 "The surface protein Pvs25 of Plasmodium vivax ookinetes interacts with calreticulin on the midgut apical surface of the malaria vector Anopheles albimanus."] is_a: IDOMAL:0001070 ! vector protein relationship: participates_in IDOMAL:0000185 ! invasion of mosquito midgut epithelium created_by: Pantelis creation_date: 2009-05-13T11:11:04Z [Term] id: IDOMAL:0001082 name: PbSub2 def: "A secreted protein expressed in ookinete stage forming protein aggregates that are often associated with the actin cytoskeleton." [PMID:11080150] synonym: "Subtisilin-like serine protease" BROAD [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001083 name: Trap def: "A transmembrane protein present on the parasite surface and in the micronemes. It is produced by sporozoites." [PMID:19148273 "Malaria parasite invasion of the mosquito salivary gland requires interaction between the Plasmodium TRAP and the Anopheles saglin proteins."] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000180 ! invasion of salivary gland created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001084 name: SIAP-1 def: "A protein expressed in oocyst - derived and salivary gland associated sporozoites." [PMID:19181869 "Disruption of Plasmodium sporozoite transmission by depletion of sporozoite invasion-associated protein 1."] synonym: "sporozoite invasion-associated protein-1" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000179 ! migration to salivary gland created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001085 name: CSP def: "A GPI anchored protein covering uniformly the external surface of sporozoites." [PMID:14668012 "The Plasmodium circumsporozoite protein is involved in mosquito salivary gland invasion by sporozoites."] synonym: "circumsporozoite protein" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000180 ! invasion of salivary gland created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001086 name: S6 def: "A sporozoite specific transmembrane protein." [PMID:19016774 "Role for the Plasmodium sporozoite-specific transmembrane protein S6 in parasite motility and efficient malaria transmission."] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000179 ! migration to salivary gland created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001087 name: Pb-PL def: "A phospholipase localized in the surface of sporozoites." [PMID:newdbxref15590623 "A surface phospholipase is involved in the migration of plasmodium sporozoites through cells."] synonym: "Plasmodium berghei phospholipase" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001088 name: human band 3 protein def: "A human protein expressed in the surface of red blood cells." [PMID:12692305 "Band 3 is a host receptor binding merozoite surface protein 1 during the Plasmodium falciparum invasion of erythrocytes."] is_a: IDOMAL:0001233 ! human host protein relationship: participates_in IDOMAL:0000479 ! erythrocyte invasion created_by: Pantelis creation_date: 2009-05-14T08:08:28Z [Term] id: IDOMAL:0001089 name: Thrombospondin related anonymous protein def: "A protein possibly playing a role in sporozoite invasion." [KL:KL] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001090 name: AMA-1 def: "A micronemal protein." [PMID:14676185 "A role for apical membrane antigen 1 during invasion of hepatocytes by Plasmodium falciparum sporozoites."] synonym: "Apical membrane antigen 1" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0001012 ! hepatocyte invasion created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001091 name: STARP def: "A sporozoite liver stage protein." [PMID:9368603 "Plasmodium falciparum sporozoite invasion is inhibited by naturally acquired or experimentally induced polyclonal antibodies to the STARP antigen."] synonym: "Sporozoite threonine and asparagines rich protein" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0001012 ! hepatocyte invasion created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001092 name: LSA-1 def: "A Plasmodium falciparum liver stage specific protein found to encode tandem 17 amino acid repeats." [PMID:7515922 "Plasmodium falciparum liver stage antigen-1 is well conserved and contains potent B and T cell determinants."] synonym: "liver stage antigen 1" RELATED [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001093 name: LSA-3 def: "A highly conserved 200 kDa protein expressed in mosquito and liver stage parasites." [PMID:11062538 "Protection against Plasmodium falciparum malaria in chimpanzees by immunization with the conserved pre-erythrocytic liver-stage antigen 3."] synonym: "liver stage antigen 3" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001094 name: SALSA def: "A protein expressed in sporozoite and liver stage of parasites." [PMID:15003642 "Sporozoite and liver stage antigen Plasmodium falciparum peptides bind specifically to human hepatocytes."] synonym: "sporozoite and liver stage antigen" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0001012 ! hepatocyte invasion created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001095 name: SPECT def: "A protein produced in sporozoites localized in a mosquito salivary gland or in the liver infective sporozoite." [PMId:14737184 "Cell-passage activity is required for the malarial parasite to cross the liver sinusoidal cell layer."] synonym: "sporozoite microneme protein essential for cell traversal" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001096 name: MAEBL def: "A single transmembrane like protein." [PMID:12021311 "MAEBL is essential for malarial sporozoite infection of the mosquito salivary gland."] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000180 ! invasion of salivary gland created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001097 name: PfSPATR def: "A protein expressed in several stages of the Plasmodium life cycle containing an altered thrombospondin repeat." [PMID:12716913 "PfSPATR, a Plasmodium falciparum protein containing an altered thrombospondin type I repeat domain is expressed at several stages of the parasite life cycle and is the target of inhibitory antibodies."] synonym: "Plasmodium falciparum secreted protein with altered thrombospondin repeat" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001098 name: Stevor def: "A protein expressed during the parasite's sexual and asexual stages." [PMID:15949631 "Peptides from the Plasmodium falciparum STEVOR putative protein bind with high affinity to normal human red blood cells."] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001099 name: Pf25-IMP def: "A 25 kDa protein which shows affinity to human red blood cells." [PMID:18556472 "Characterization of Plasmodium falciparum integral membrane protein Pf25-IMP and identification of its red blood cell binding sequences inhibiting merozoite invasion in vitro."] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000479 ! erythrocyte invasion created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001100 name: MCP-1 def: "A 60 kDa protein located at the merozoite apical region and erythrocyte." [PMID:2671726 "A 60-kDa Plasmodium falciparum protein at the moving junction formed between merozoite and erythrocyte during invasion."] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000479 ! erythrocyte invasion created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001101 name: PbROM1 def: "A serine protease present in blood stage merozoites localized to the apical end." [PMID:19148267 "Distinct roles of Plasmodium rhomboid 1 in parasite development and malaria pathogenesis."] synonym: "rhomboid protease" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001102 name: PfROM-1 def: "A rhoptric protease, highly specific able to cleave diverse adhesins." [PMID:17596999 "Erythrocyte invasion: vocabulary and grammar of the Plasmodium rhoptry."] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000479 ! erythrocyte invasion created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001103 name: PfROM-4 def: "A specific rhoptric protease able to cleave diverse adhesins." [PMID:17596999 "Erythrocyte invasion: vocabulary and grammar of the Plasmodium rhoptry."] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001104 name: PfSUB1 def: "A subtilisin like serine protease discharged from exonemes into parasitoforous vacuole space." [PMID:19214190 "A multifunctional serine protease primes the malaria parasite for red blood cell invasion."] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000480 ! Plasmodium recognition and attachment to erythrocyte created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001105 name: PfSUB2 def: "An integral membrane subtilisin like protease stored in micronemes." [PMID:16322767 "Molecular identification of a malaria merozoite surface sheddase."] synonym: "merozoite surface sheddase" EXACT [] synonym: "MESH" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000480 ! Plasmodium recognition and attachment to erythrocyte created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001106 name: HAP def: "An active enzyme involved in heamoglobin degradation." [PMID:15899698 "P. falciparum pro-histoaspartic protease (proHAP) protein peptides bind specifically to erythrocytes and inhibit the invasion process in vitro."] synonym: "Plasmodium falciparum histoaspartic protease" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000480 ! Plasmodium recognition and attachment to erythrocyte created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001107 name: laminin gamma1 def: "A specific protein of a vector." [KL:KL] is_a: IDOMAL:0001070 ! vector protein created_by: Pantelis creation_date: 2009-05-13T12:19:20Z [Term] id: IDOMAL:0001108 name: GBP-130 def: "A merozoite surface protein consisting of a charged, 225-residue-long N-terminal region and eleven 50-residue-long repeat sequences that binds to the RBC surface." [PMID:3512098 "A tandemly repeated sequence determines the binding domain for an erythrocyte receptor binding protein of P. falciparum."] synonym: "glycophorin binding protein 130" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000479 ! erythrocyte invasion created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001109 name: SERA-5 def: "A protease expressed in merozoites as a protomer that is subsequently processed into four fragments." [PMID:12228245 "A subset of Plasmodium falciparum SERA genes are expressed and appear to play an important role in the erythrocytic cycle."] synonym: "serine repeat antigen 5" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001110 name: Pf12 def: "A merozoite protein containing six-cystein motifs." [PMID:16203726 "Distinct protein classes including novel merozoite surface antigens in Raft-like membranes of Plasmodium falciparum."] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001111 name: Pf38 def: "A merozoite protein containing six-cystein motifs." [PMID:16203726 "Distinct protein classes including novel merozoite surface antigens in Raft-like membranes of Plasmodium falciparum."] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001112 name: Pf41 def: "A merozoite protein containing six-cystein motifs." [PMID:16203726 "Distinct protein classes including novel merozoite surface antigens in Raft-like membranes of Plasmodium falciparum."] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001113 name: Pf92 def: "A merozoite protein containing six-cystein motifs." [PMID:16203726 "Distinct protein classes including novel merozoite surface antigens in Raft-like membranes of Plasmodium falciparum."] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001114 name: Pf113 def: "A merozoite protein containing six-cystein motifs." [PMID:16203726 "Distinct protein classes including novel merozoite surface antigens in Raft-like membranes of Plasmodium falciparum."] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001115 name: EBA-175 def: "An 175 kDa protein localized in micronemes." [PMID:8009226 "Receptor and ligand domains for invasion of erythrocytes by Plasmodium falciparum."] synonym: "erythrocyte binding antigen - 175" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000479 ! erythrocyte invasion created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001116 name: BAEBL def: "A protein expressed in late schizogony localized in micronemes. Paralogue of EBA-175." [PMID:12576308 "Glycophorin C is the receptor for the Plasmodium falciparum erythrocyte binding ligand PfEBP-2 (baebl)"] synonym: "EBA-140" EXACT [] synonym: "PfEBP-2" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001117 name: JESEBL def: "A 181 kDa protein expressed in the late schizont stage and located in the micronemes." [PMID:15820749 "Amino terminal peptides from the Plasmodium falciparum EBA-181/JESEBL protein bind specifically to erythrocytes and inhibit in vitro merozoite invasion"] synonym: "EBA-181" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001118 name: EBL-1 def: "A protein expressed in the late schizont stage and located in the micronemes." [PMID:2884039 "A histidine-rich protein gene marks a linkage group favored strongly in a genetic cross of Plasmodium falciparum"] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001119 name: PfRBP-H1 def: "A rhoptry protein." [PMID:11733572 "A Plasmodium falciparum homologue of Plasmodium vivax reticulocyte binding protein (PvRBP1) defines a trypsin-resistant erythrocyte invasion pathway"] synonym: "PfNBP-1" EXACT [] synonym: "Plasmodium falciparum normocyte binding protein -1" EXACT [] synonym: "Plasmodium falciparum reticulocyte binding protein homologue 1" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001120 name: PfRBP-2Ha def: "A 370 kDa protein located in rhoptries of merozoites." [PMID:12606570 "Phenotypic variation of Plasmodium falciparum merozoite proteins directs receptor targeting for invasion of human erythrocytes"] synonym: "reticulocyte binding protein 2 homologue a" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000479 ! erythrocyte invasion created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001121 name: PfRBP-2Hb def: "A 350 kDa protein located in rhoptries." [PMID:12228308 "Variation in the expression of a Plasmodium falciparum protein family implicated in erythrocyte invasion"] synonym: "reticulocyte binding protein 2 homologue b" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000479 ! erythrocyte invasion created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001122 name: PfRh4 def: "A 220 kDa transmembrane merozoite protein." [XX:12034462 "Gene structure and expression of a Plasmodium falciparum 220-kDa protein homologous to the Plasmodium vivax reticulocyte binding proteins"] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001123 name: RAP-1 def: "A rhoptry protein present during asexual blood stage parasite development." [PMID:10835342 "RAP1 controls rhoptry targeting of RAP2 in the malaria parasite Plasmodium falciparum"] synonym: "rhoptry associated protein 1" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001124 name: RAP-2 def: "A merozoite rhoptry protein with a molecular weight of 40-42 kDa." [PMID:2200961 "Characterisation and sequence of a protective rhoptry antigen from Plasmodium falciparum"] synonym: "RAP2" EXACT [] synonym: "rhoptry associated protein 2" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001125 name: RAP-3 def: "A 37-40 kDa protein located in merozoite rhoptries." [PMID:12183575 "Identification and disruption of the gene encoding the third member of the low-molecular-mass rhoptry complex in Plasmodium falciparum"] synonym: "rhoptry associated protein 3" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001126 name: clag9 def: "A high molecular weight protein expressed in rhoptries." [PMID:11738712 "The high molecular mass rhoptry protein, RhopH1, is encoded by members of the clag multigene family in Plasmodium falciparum and Plasmodium yoelii"] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001127 name: RhopH3 def: "A 110-kDa rhoptry protein secreted from the organelle into the erythrocyte membrane." [PMID:1889471 "Interaction of the 140/130/110 kDa rhoptry protein complex of Plasmodium falciparum with the erythrocyte membrane and liposomes"] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001128 name: RAMA def: "A 60 kDa protein anchored to merozoite membrane via its GPI tail." [PMID:16088836 "Antibodies to rhoptry-associated membrane antigen predict resistance to Plasmodium falciparum"] synonym: "rhoptry associated membrane antigen" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001129 name: RESA-155 def: "A 155 kDa protein expressed on the surface of ring infected red blood cell." [PMID:3537955 "Structure of the RESA gene of Plasmodium falciparum"] synonym: "Ring infected erythrocyte surface antigen" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001130 name: RESA-like protein def: "A protein synthesized during early ring stages and transported to infected red blood cells membrane surface during the trophozoite stage." [PMID:12368864 "Genome sequence of the human malaria parasite Plasmodium falciparum"] synonym: "ring infected erythrocyte surface antigen like protein" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001131 name: HRP-I def: "A conserved protein 85 to 105 kDa expressed during the middle and late stages of the malarial parasite asexual cycle." [PMID:3301325 "The complete sequence of the gene for the knob-associated histidine-rich protein from Plasmodium falciparum"] synonym: "histidine rich protein I" EXACT [] synonym: "KAHRP" EXACT [] synonym: "knob associated histidine rich protein" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001132 name: HRP-II def: "A secreted soluble protein present in parasite cytoplasm." [PMID:10518033 "Heme binding and polymerization by Plasmodium falciparum histidine rich protein II: influence of pH on activity and conformation"] synonym: "histidine rich protein II" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001133 name: MAHRP-1 def: "A 29 kDa protein located in Maurer's clefts." [PMID:12815049 "MAHRP-1, a novel Plasmodium falciparum histidine-rich protein, binds ferriprotoporphyrin IX and localizes to the Maurer's clefts", XX:newdbxref] synonym: "Plasmodium falciparum membrane associated histidine rich protein 1" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001134 name: PfEMP-1 def: "A knob-associated cytoadherent protein." [PMID:17398133 "The naturally acquired immunity in severe malaria and its implication for a PfEMP-1 based vaccine", PMID:1773882 "Knobs, knob proteins and cytoadherence in falciparum malaria"] synonym: "Plasmodium falciparum erythrocyte membrane protein 1" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in GO:0020013 ! rosetting relationship: participates_in IDOMAL:0000107 ! CD36 recognition relationship: participates_in IDOMAL:0000704 ! sequestration in malaria created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001135 name: PvRBR-1 def: "A 325 kDa protein expressed in the apical pole of the merozoite." [PMID:1617731 "A reticulocyte-binding protein complex of Plasmodium vivax merozoites"] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001136 name: PvRBR-2 def: "A 330 kDa protein expressed in the apical pole of the merozoite." [PMID:1617731 "A reticulocyte-binding protein complex of Plasmodium vivax merozoites"] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001137 name: Py235 def: "A 235kDA rhoptry protein." [PMID:11378199 "Distribution and characterisation of the 235 kDa rhoptry multigene family within the genomes of virulent and avirulent lines of Plasmodium yoelii"] synonym: "reticulocyte binding protein" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001138 name: PvDBP def: "A Plasmodium vivax protein which binds to Duffy blood group antigen." [PMID:19000655 "Identification and evaluation of universal epitopes in Plasmodium vivax Duffy binding protein"] synonym: "Plasmodium vivax duffy binding protein" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:07:12Z [Term] id: IDOMAL:0001139 name: PPLP-1 def: "A putative secreted protein conserved across the Plasmodium species characterized by a MACPF-like domain." [PMID:14668008 "A member of a conserved Plasmodium protein family with membrane-attack complex/perforin (MACPF)-like domains localizes to the micronemes of sporozoites."] synonym: "SPECT-2" EXACT [PMID:newdbxref15659064 "A Plasmodium sporozoite protein with a membrane attack complex domain is required for breaching the liver sinusoidal cell layer prior to hepatocyte infection"] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:08:51Z [Term] id: IDOMAL:0001140 name: PPLP-2 def: "A putative secreted protein conserved across the Plasmodium species characterized by a MACPF-like domain." [PMID:144668008 "A member of a conserved Plasmodium protein family with membrane-attack complex/perforin (MACPF)-like domains localizes to the micronemes of sporozoites."] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:08:51Z [Term] id: IDOMAL:0001141 name: PPLP-3 def: "A putative secreted protein conserved across the Plasmodium species characterized by a MACPF-like domain." [PMID:144668008 "A member of a conserved Plasmodium protein family with membrane-attack complex/perforin (MACPF)-like domains localizes to the micronemes of sporozoites."] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000185 ! invasion of mosquito midgut epithelium created_by: Pantelis creation_date: 2009-05-10T08:08:51Z [Term] id: IDOMAL:0001142 name: PPLP-4 def: "A putative secreted protein conserved across the Plasmodium species characterized by a MACPF-like domain." [PMID:144668008 "A member of a conserved Plasmodium protein family with membrane-attack complex/perforin (MACPF)-like domains localizes to the micronemes of sporozoites."] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:08:51Z [Term] id: IDOMAL:0001143 name: MSP-1 def: "Two Plasmodium falciparum merozoite proteins binding to erythrocyte band 3 form a direct complex." [PMID:12692305 "Band 3 is a host receptor binding merozoite surface protein 1 during the Plasmodium falciparum invasion of erythrocytes."] synonym: "merozoite surface protein 1" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000479 ! erythrocyte invasion created_by: Pantelis creation_date: 2009-05-10T08:10:05Z [Term] id: IDOMAL:0001144 name: MSP-2 def: "A major membrane protein attached to the merozoite surface through a GPI anchor." [PMID:3293051 "Identification of two integral membrane proteins of Plasmodium falciparum."] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:10:05Z [Term] id: IDOMAL:0001145 name: MSP-3 def: "A 48 kDa protein derived from a variable higher molecular weight precursor protein and undergoes proteolytic processing in the parasitoforous vacuole before secreted on the merozoite surface." [PMID:7891748 "Molecular variation in a novel polymorphic antigen associated with Plasmodium falciparum merozoites"] synonym: "merozoite surface protein 3" EXACT [] synonym: "secreted polymorphic antigen associated with merozoites" EXACT [] synonym: "SPAM" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000157 ! schizogony created_by: Pantelis creation_date: 2009-05-10T08:10:05Z [Term] id: IDOMAL:0001146 name: MSP-4 def: "A major membrane protein attached to the merozoite surface through a GPI anchor." [PMID:17944453 "Identifying merozoite surface protein 4 and merozoite surface protein 7 Plasmodium falciparum protein family members specifically binding to human erythrocytes suggests a new malarial parasite-redundant survival mechanism."] synonym: "merozoite surface protein 4" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000480 ! Plasmodium recognition and attachment to erythrocyte created_by: Pantelis creation_date: 2009-05-10T08:10:05Z [Term] id: IDOMAL:0001147 name: MSP-5 def: "A major membrane protein attached to the merozoite surface through a GPI anchor." [PMID:9719507 "Close linkage of three merozoite surface protein genes on chromosome 2 of Plasmodium falciparum."] synonym: "merozoite surface protein 5" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:10:05Z [Term] id: IDOMAL:0001148 name: MSP-6 def: "A major membrane protein attached to the merozoite surface through a GPI anchor." [PMID:15039357 "Plasmodium falciparum merozoite surface protein 6 is a dimorphic antigen."] synonym: "merozoite surface protein 6" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:10:05Z [Term] id: IDOMAL:0001149 name: MSP-7 def: "A major membrane protein attached to the merozoite surface through a GPI anchor." [PMID:17944453 "Identifying merozoite surface protein 4 and merozoite surface protein 7 Plasmodium falciparum protein family members specifically binding to human erythrocytes suggests a new malarial parasite-redundant survival mechanism."] synonym: "merozoite surface protein 7" RELATED [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:10:05Z [Term] id: IDOMAL:0001150 name: MSP-8 def: "A 69.4 kDa intracellular membrane protein that is transcribed and translated in the ring stage localized to the parasite plasma membrane and it is absent from the surface of merozoites." [PMID:15972477 "Plasmodium falciparum merozoite surface protein 8 is a ring-stage membrane protein that localizes to the parasitophorous vacuole of infected erythrocytes."] synonym: "merozoite surface protein 8" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:10:05Z [Term] id: IDOMAL:0001151 name: MSP-9 def: "A 191 kDa protein located on merozoite surface and on infected red blood cells within the parasitoforous vacuole." [PMID:16289042 "Two Plasmodium falciparum merozoite proteins binding to erythrocyte band 3 form a direct complex."] synonym: "ABRA" EXACT [] synonym: "acid basic repeat antigen" EXACT [] synonym: "merozoite surface protein 9" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000479 ! erythrocyte invasion created_by: Pantelis creation_date: 2009-05-10T08:10:05Z [Term] id: IDOMAL:0001152 name: MSP-10 def: "A 61.2 kDa protein anchored to the merozoite membrane via GPI." [PMID:15820753 "Identifying Plasmodium falciparum merozoite surface protein-10 human erythrocyte specific binding regions."] synonym: "merozoite surface protein 10" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-10T08:10:05Z [Term] id: IDOMAL:0001153 name: PPLP-5 def: "A putative secreted protein conserved across the Plasmodium species characterized by a MACPF-like domain." [PMID:144668008 "A member of a conserved Plasmodium protein family with membrane-attack complex/perforin (MACPF)-like domains localizes to the micronemes of sporozoites."] is_a: IDOMAL:0001069 ! Plasmodium parasite protein relationship: participates_in IDOMAL:0000185 ! invasion of mosquito midgut epithelium created_by: Pantelis creation_date: 2009-05-13T07:42:51Z [Term] id: IDOMAL:0001154 name: saglin def: "A secreted protein expressed in the salivary glands of Anopheles gambiae." [PMID:18093000 "Identification and molecular characterization of a novel protein Saglin as a target of monoclonal antibodies affecting salivary gland infectivity of Plasmodium sporozoites."] is_a: IDOMAL:0001070 ! vector protein relationship: participates_in IDOMAL:0000180 ! invasion of salivary gland created_by: Pantelis creation_date: 2009-05-13T08:16:54Z [Term] id: IDOMAL:0001155 name: human glycophorin A def: "Glycophorin A is a sialoglycoprotein isolated from human erythrocyte membranes which seems to exist as stable dimeric complexes in the presence of sodium dodecyl sulfate." [PMID:175830 "Subunit structure of human erythrocyte glycophorin A."] is_a: IDOMAL:0001233 ! human host protein relationship: participates_in IDOMAL:0000479 ! erythrocyte invasion created_by: Pantelis creation_date: 2009-05-14T09:38:16Z [Term] id: IDOMAL:0001156 name: human glycophorin C def: "A protein expressed in the membrane of erythrocytes." [PMID:732312 "Glycophorins A, B, and C: a family of sialoglycoproteins. Isolation and preliminary characterization of trypsin derived peptides."] synonym: "sialoglycoprotein D" EXACT [] is_a: IDOMAL:0001233 ! human host protein created_by: Pantelis creation_date: 2009-05-14T10:26:14Z [Term] id: IDOMAL:0001157 name: PTRAMP def: "A 352 amino acid protein with a putative signal sequence, transmembrane domain and thrombospondin structural homology repeat." [PMID:15003842 "PTRAMP; a conserved Plasmodium thrombospondin-related apical merozoite protein"] synonym: "Plasmodium thrombospondin-related apical merozoite protein" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-14T10:44:02Z [Term] id: IDOMAL:0001158 name: RhopH2 def: "A 130-kDa rhoptry protein secreted from the organelle into the erythrocyte membrane." [PMID:7496381 "Plasmodium falciparum rhoptry proteins of 140/130/110 kd (Rhop-H) are located in an electron lucent compartment in the neck of the rhoptries"] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-14T11:34:56Z [Term] id: IDOMAL:0001159 name: human spectrin def: "A major component of red blood cell's cytoskeleton." [PMID:15998 "elective association of spectrin with the cytoplasmic surface of human erythrocyte plasma membranes. Quantitative determination with purified (32P)spectrin"] is_a: IDOMAL:0001233 ! human host protein created_by: Pantelis creation_date: 2009-05-15T12:25:31Z [Term] id: IDOMAL:0001160 name: clag2 def: "A rhoptry protein located in the merozoite apical extreme." [PMID:18155305 "Diversity and evolution of the rhoph1/clag multigene family of Plasmodium falciparum"] synonym: "rhoph1/clag2" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-15T12:06:06Z [Term] id: IDOMAL:0001161 name: clag3.1 def: "A rhoptry protein located in the merozoite apical extreme." [PMID:18155305 "Diversity and evolution of the rhoph1/clag multigene family of Plasmodium falciparum"] synonym: "rhoph1/clag3.1" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-15T12:06:06Z [Term] id: IDOMAL:0001162 name: clag3.2 def: "A rhoptry protein located in the merozoite apical extreme." [PMID:18155305 "Diversity and evolution of the rhoph1/clag multigene family of Plasmodium falciparum"] synonym: "rhoph1/clag3.2" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-15T12:06:06Z [Term] id: IDOMAL:0001163 name: clag8 def: "A rhoptry protein located in the merozoite apical extreme." [PMID:18155305 "Diversity and evolution of the rhoph1/clag multigene family of Plasmodium falciparum"] synonym: "rhoph1/clag8" EXACT [] is_a: IDOMAL:0001069 ! Plasmodium parasite protein created_by: Pantelis creation_date: 2009-05-15T12:06:06Z [Term] id: IDOMAL:0001164 name: human actin def: "Actin is a globular, roughly 42-kDa highly conserved protein found in almost all eukaryotic cells. It is also one of the most highly-conserved proteins, differing by no more than 20% in species as diverse as algae and humans. Actin is the monomeric subunit of two types of filaments in cells: microfilaments, one of the three major components of the cytoskeleton, and thin filaments, part of the contractile apparatus in muscle cells." [Wikipedia:actin] is_a: IDOMAL:0001233 ! human host protein created_by: Pantelis creation_date: 2009-05-15T12:25:31Z [Term] id: IDOMAL:0001165 name: human ankyrin def: "A membrane protein identified as the target of spectrin a cytoskeletal protein." [PMID:372182 "Identification and partial purification of ankyrin, the high affinity membrane attachment site for human erythrocyte spectrin"] is_a: IDOMAL:0001233 ! human host protein created_by: Pantelis creation_date: 2009-05-15T12:25:31Z [Term] id: IDOMAL:0001166 name: human band 4.1 protein def: "A protein expressed in erythrocytes." [PMID:965498 "Irreversible deformation of the spectrin-actin lattice in irreversibly sickled cells"] is_a: IDOMAL:0001233 ! human host protein created_by: Pantelis creation_date: 2009-05-15T12:25:58Z [Term] id: IDOMAL:0001167 name: heparin def: "A glycosaminoglycan with highest negative charge density of any known biological molecule." [KL:KL] is_a: MIRO:10000171 ! glycosaminoglycan created_by: Pantelis creation_date: 2009-05-15T12:55:54Z [Term] id: IDOMAL:0001169 name: complement receptor 1 def: "It is a membrane glycoprotein found on various cell types like human erythrocytes, monocytes, polymorphonuclear leukocytes, and B cells. It is member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1." [ISBN:0-8493-1567-0 "Atlas of Immunology", Wikipedia:Complementreceptor1] synonym: "C3b/C4b receptor" EXACT [] synonym: "CD35" NARROW [] synonym: "CR1" EXACT [] synonym: "immune adherence receptor" BROAD [] is_a: IDOMAL:0001233 ! human host protein relationship: has_role IDOMAL:0000373 ! receptor relationship: participates_in GO:0020013 ! rosetting relationship: participates_in IDOMAL:0000104 ! complement receptor 1 recognition created_by: Pantelis creation_date: 2009-05-15T12:55:54Z [Term] id: IDOMAL:0001170 name: chondroitin sulphate def: "A glycosaminoglycan, the most prevalent GAG." [KL:KL] is_a: MIRO:10000171 ! glycosaminoglycan created_by: Pantelis creation_date: 2009-05-15T12:55:54Z [Term] id: IDOMAL:0001171 name: human Duffy blood group antigen def: "A 35 to 43 kDa protein found in erythrocytes. Duffy-negative individuals are completely resistant to P. vivax infections." [PMID:14802995 "The Duffy blood group system", PMID:6695171 "Identification of an erythrocyte component carrying the Duffy blood group Fya antigen"] is_a: IDOMAL:0001233 ! human host protein created_by: Pantelis creation_date: 2009-05-15T01:13:07Z [Term] id: IDOMAL:0001175 name: Anopheles breeding site def: "A collection of water which provides habitat for anopheline larvae and on which a female mosquito lays its eggs." [KL:KL] is_a: IDOMAL:0001034 ! abiotic created_by: louis creation_date: 2009-06-03T12:01:46Z [Term] id: IDOMAL:0001176 name: permanent or semi-permanent standing fresh water def: "A larger collection of non-salty water, natural (e.g. lake) or artificial (e.g. pool)." [KL:KL] is_a: IDOMAL:0001175 ! Anopheles breeding site created_by: louis creation_date: 2009-06-03T12:06:07Z [Term] id: IDOMAL:0001177 name: transient fresh water collection def: "Smaller rain-filled depressions." [KL:KL] is_a: IDOMAL:0001175 ! Anopheles breeding site created_by: louis creation_date: 2009-06-03T12:06:07Z [Term] id: IDOMAL:0001178 name: permanent or semi-permanent running fresh water def: "Non-salty water that flaws naturally (e.g. stream) or artificially (e.g. canal)." [KL:KL] is_a: IDOMAL:0001175 ! Anopheles breeding site created_by: louis creation_date: 2009-06-03T12:06:07Z [Term] id: IDOMAL:0001179 name: container habitat def: "Water that was collected in an artificial container, eg through rain or otherwise." [KL:KL] is_a: IDOMAL:0001175 ! Anopheles breeding site created_by: louis creation_date: 2009-06-03T12:06:07Z [Term] id: IDOMAL:0001180 name: brackish water def: "Brackish water is water that has more salinity than fresh water, but not as much as seawater." [KL:KL] is_a: IDOMAL:0001175 ! Anopheles breeding site created_by: louis creation_date: 2009-06-03T12:06:07Z [Term] id: IDOMAL:0001181 name: pool in a field def: "A transient accumulation of rain water in a depression on a field." [KL:KL] is_a: IDOMAL:0001177 ! transient fresh water collection created_by: louis creation_date: 2009-06-03T12:15:05Z [Term] id: IDOMAL:0001182 name: stagnant stream bed def: "A water pool in stream that has either permanently or temporally lost its water." [KL:KL] is_a: IDOMAL:0001177 ! transient fresh water collection created_by: louis creation_date: 2009-06-03T12:15:05Z [Term] id: IDOMAL:0001183 name: water-filled cattle hoof print def: "A depression made by an animal hoof while the soil was wet and later dried and filled with rain water." [KL:KL] is_a: IDOMAL:0001177 ! transient fresh water collection created_by: louis creation_date: 2009-06-03T12:15:05Z [Term] id: IDOMAL:0001184 name: pool in car track def: "A rain water-filled track of a tyre left in mud and later dried." [KL:KL] is_a: IDOMAL:0001177 ! transient fresh water collection created_by: louis creation_date: 2009-06-03T12:15:05Z [Term] id: IDOMAL:0001185 name: brackish water marsh def: "A coastel marsh (low poorly drained land) with brackish water." [KL:KL] is_a: IDOMAL:0001180 ! brackish water created_by: louis creation_date: 2009-06-03T12:28:02Z [Term] id: IDOMAL:0001186 name: brackish water pond def: "A still body of brackish water." [KL:KL] is_a: IDOMAL:0001180 ! brackish water created_by: louis creation_date: 2009-06-03T12:28:02Z [Term] id: IDOMAL:0001187 name: brackish water non-tidal swamp def: "A coastal region saturated with brackish water." [KL:KL] is_a: IDOMAL:0001180 ! brackish water created_by: louis creation_date: 2009-06-03T12:28:02Z [Term] id: IDOMAL:0001188 name: tidal swamp def: "A swanp whose water content depends on the tides." [KL:KL] is_a: IDOMAL:0001180 ! brackish water created_by: louis creation_date: 2009-06-03T12:28:02Z [Term] id: IDOMAL:0001189 name: small collection of brackish water def: "Any small collection of brackish water." [KL:KL] is_a: IDOMAL:0001180 ! brackish water created_by: louis creation_date: 2009-06-03T12:28:02Z [Term] id: IDOMAL:0001190 name: rock hole def: "A depression in a rock in which water could accumulate." [KL:KL] is_a: IDOMAL:0001179 ! container habitat created_by: louis creation_date: 2009-06-03T12:29:38Z [Term] id: IDOMAL:0001191 name: tree hole def: "A natural cavity in a tree." [KL:KL] is_a: IDOMAL:0001179 ! container habitat created_by: louis creation_date: 2009-06-03T12:29:38Z [Term] id: IDOMAL:0001192 name: plan axil def: "The angle between the upper side of the stem and a leaf, branch, or petiole." [KL:KL] is_a: IDOMAL:0001179 ! container habitat created_by: louis creation_date: 2009-06-03T12:29:38Z [Term] id: IDOMAL:0001193 name: epiphytic water-bearing plant def: "An epiphytic plant in which water accumulates." [KL:KL] is_a: IDOMAL:0001179 ! container habitat created_by: louis creation_date: 2009-06-03T12:29:38Z [Term] id: IDOMAL:0001194 name: discarded container def: "Any kind of container that has been discarded in the environment by man." [KL:KL] is_a: IDOMAL:0001179 ! container habitat created_by: louis creation_date: 2009-06-03T12:29:38Z [Term] id: IDOMAL:0001195 name: crab hole def: "A small hole in the soil used as a habitat by crabs." [KL:KL] is_a: IDOMAL:0001179 ! container habitat created_by: louis creation_date: 2009-06-03T12:29:38Z [Term] id: IDOMAL:0001196 name: crack in mud def: "A crack in dried mud." [KL:KL] is_a: IDOMAL:0001179 ! container habitat created_by: louis creation_date: 2009-06-03T12:29:38Z [Term] id: IDOMAL:0001197 name: natural discarded container def: "Any kind of natural container that has been discarded in the environment by man, such as a coconut husk." [KL:KL] is_a: IDOMAL:0001194 ! discarded container created_by: louis creation_date: 2009-06-03T12:30:23Z [Term] id: IDOMAL:0001198 name: artificial discarded container def: "Any kind of artificial container that has been discarded in the environment by man, such as a tin, a bottle or a used tyre." [KL:KL] is_a: IDOMAL:0001194 ! discarded container created_by: louis creation_date: 2009-06-03T12:30:23Z [Term] id: IDOMAL:0001199 name: open stream with vegetation def: "Fresh water running in a small stream with vegetation." [KL:KL] is_a: IDOMAL:0001178 ! permanent or semi-permanent running fresh water created_by: louis creation_date: 2009-06-03T12:32:07Z [Term] id: IDOMAL:0001200 name: stream bed running over gravel def: "Fresh water running in a small stream over gravel or similar material." [KL:KL] is_a: IDOMAL:0001178 ! permanent or semi-permanent running fresh water created_by: louis creation_date: 2009-06-03T12:32:07Z [Term] id: IDOMAL:0001201 name: flowing water in canal def: "Fresh water running slowly in a man-made canal." [KL:KL] is_a: IDOMAL:0001178 ! permanent or semi-permanent running fresh water created_by: louis creation_date: 2009-06-03T12:32:07Z [Term] id: IDOMAL:0001202 name: flawing water in ditch def: "Fresh water running slowly in a man-made ditch." [KL:KL] is_a: IDOMAL:0001178 ! permanent or semi-permanent running fresh water created_by: louis creation_date: 2009-06-03T12:32:07Z [Term] id: IDOMAL:0001203 name: stream in forest def: "Fresh water running in a small stream in a forest." [KL:KL] is_a: IDOMAL:0001178 ! permanent or semi-permanent running fresh water created_by: louis creation_date: 2009-06-03T12:32:07Z [Term] id: IDOMAL:0001204 name: stream in plantation def: "Fresh water running in a small natural stream in a plantation." [KL:KL] is_a: IDOMAL:0001178 ! permanent or semi-permanent running fresh water created_by: louis creation_date: 2009-06-03T12:32:07Z [Term] id: IDOMAL:0001205 name: large open marsh def: "A marsh, or morass, is a type of wetland which is subject to frequent or continuous flood." [Wikipedia:Marsh] is_a: IDOMAL:0001176 ! permanent or semi-permanent standing fresh water created_by: louis creation_date: 2009-06-03T12:35:51Z [Term] id: IDOMAL:0001206 name: marshy part of lake def: "Thye part of a larger lake that resembles a marsh." [KL:KL] is_a: IDOMAL:0001176 ! permanent or semi-permanent standing fresh water created_by: louis creation_date: 2009-06-03T12:35:51Z [Term] id: IDOMAL:0001207 name: small pond def: "A pond is an inland body of standing water, either natural or man-made, that is smaller than a lake." [Wikipedia:pond] is_a: IDOMAL:0001176 ! permanent or semi-permanent standing fresh water created_by: louis creation_date: 2009-06-03T12:35:51Z [Term] id: IDOMAL:0001208 name: small pool def: "A small, deep body of water." [KL:KL] is_a: IDOMAL:0001176 ! permanent or semi-permanent standing fresh water created_by: louis creation_date: 2009-06-03T12:35:51Z [Term] id: IDOMAL:0001209 name: borrow-pit def: "An area where material (usually soil, gravel or sand) has been dug for use at another location." [Wikipedia:borrowpit] is_a: IDOMAL:0001176 ! permanent or semi-permanent standing fresh water created_by: louis creation_date: 2009-06-03T12:35:51Z [Term] id: IDOMAL:0001210 name: stagnant canal def: "A man-made canal in which water is stagnant due to the lack of natural flow." [KL:KL] is_a: IDOMAL:0001176 ! permanent or semi-permanent standing fresh water created_by: louis creation_date: 2009-06-03T12:35:51Z [Term] id: IDOMAL:0001211 name: stagnant ditch def: "A man-made ditch in which water is stagnant due to the lack of natural flow." [KL:KL] is_a: IDOMAL:0001176 ! permanent or semi-permanent standing fresh water created_by: louis creation_date: 2009-06-03T12:35:51Z [Term] id: IDOMAL:0001212 name: spring-fed pool def: "A pool close to, and fed by a spring." [KL:KL] is_a: IDOMAL:0001176 ! permanent or semi-permanent standing fresh water created_by: louis creation_date: 2009-06-03T12:35:51Z [Term] id: IDOMAL:0001213 name: spring def: "A natural source of water." [KL:KL] is_a: IDOMAL:0001176 ! permanent or semi-permanent standing fresh water created_by: louis creation_date: 2009-06-03T12:35:51Z [Term] id: IDOMAL:0001214 name: seepage from higher contours def: "An area in which water flows through pores and accumulates." [KL:KL] is_a: IDOMAL:0001176 ! permanent or semi-permanent standing fresh water created_by: louis creation_date: 2009-06-03T12:35:51Z [Term] id: IDOMAL:0001215 name: rice field def: "A flooded parcel of arable land used for growing rice." [KL:KL] synonym: "paddy field" NARROW [] is_a: IDOMAL:0001176 ! permanent or semi-permanent standing fresh water created_by: louis creation_date: 2009-06-03T12:35:51Z [Term] id: IDOMAL:0001216 name: standing water in plantation def: "Standing water in a plantation, coming from irrigation." [KL:KL] is_a: IDOMAL:0001176 ! permanent or semi-permanent standing fresh water created_by: louis creation_date: 2009-06-03T12:35:51Z [Term] id: IDOMAL:0001217 name: open well def: "An uncovered artificial excavation, hole or structure for the purpose of withdrawing water." [KL:KL] is_a: IDOMAL:0001176 ! permanent or semi-permanent standing fresh water created_by: louis creation_date: 2009-06-03T12:35:51Z [Term] id: IDOMAL:0001218 name: swamp in forest def: "A swamp in a forest." [KL:KL] is_a: IDOMAL:0001176 ! permanent or semi-permanent standing fresh water created_by: louis creation_date: 2009-06-03T12:35:51Z [Term] id: IDOMAL:0001219 name: monkey def: "Any primate that is not a prosimian (lemurs and tarsiers) or an ape." [KL:KL] is_a: IDOMAL:0000606 ! primate created_by: louis creation_date: 2009-06-03T02:20:26Z [Term] id: IDOMAL:0001220 name: ape def: "An ape is any member of the Hominoidea superfamily of primates." [KL:KL] is_a: IDOMAL:0000606 ! primate created_by: louis creation_date: 2009-06-03T02:20:26Z [Term] id: IDOMAL:0001221 name: chimpanzee def: "A taxon comprising two species of apes." [KL:KL] synonym: "Pan" EXACT [] is_a: IDOMAL:0001220 ! ape created_by: louis creation_date: 2009-06-03T02:22:20Z [Term] id: IDOMAL:0001222 name: gorilla def: "Any primate species of the genus Gorilla." [KL:KL] is_a: IDOMAL:0001220 ! ape created_by: louis creation_date: 2009-06-03T02:22:20Z [Term] id: IDOMAL:0001223 name: orangutan def: "Any of the two ape species of the genus Pongo." [KL:KL] is_a: IDOMAL:0001220 ! ape created_by: louis creation_date: 2009-06-03T02:22:20Z [Term] id: IDOMAL:0001224 name: bonobo def: "A chimp species found in the forests of the RDC." [KL:KL] synonym: "Pan paniscus" EXACT [] synonym: "Pygmy chimpanzee" EXACT [] is_a: IDOMAL:0001221 ! chimpanzee created_by: louis creation_date: 2009-06-03T02:25:04Z [Term] id: IDOMAL:0001225 name: chimpanzee sensu stricto def: "A chimp species found in West and Central Africa." [KL:KL] synonym: "Pan troglodytes" EXACT [] is_a: IDOMAL:0001221 ! chimpanzee created_by: louis creation_date: 2009-06-03T02:25:04Z [Term] id: IDOMAL:0001227 name: Plasmodium cynomolgi def: "A South East Asia macaque parasite." [KL:KL] is_a: IDOMAL:0000127 ! subgenus Plasmodium relationship: has_role IDOMAL:0001269 ! monkey malaria parasite created_by: louis creation_date: 2009-06-03T03:42:53Z [Term] id: IDOMAL:0001228 name: Plasmodium knowlesi def: "A parasite causing malaria to monkeys and also found to be causing malaria naturally to humans in SE Asia." [KL:KL] is_a: IDOMAL:0000127 ! subgenus Plasmodium relationship: has_role IDOMAL:0001269 ! monkey malaria parasite created_by: louis creation_date: 2009-06-03T03:47:12Z [Term] id: IDOMAL:0001229 name: Plasmodium berghei def: "An African rodent parasite, often used as a model." [KL:KL] is_a: IDOMAL:0000127 ! subgenus Plasmodium relationship: has_role IDOMAL:0001267 ! rodent malaria parasite created_by: louis creation_date: 2009-06-04T08:17:35Z [Term] id: IDOMAL:0001230 name: Plasmodium gallinaceum def: "A Southe East Asian parasite, often used as a model." [KL:KL] is_a: IDOMAL:0000127 ! subgenus Plasmodium relationship: has_role IDOMAL:0001268 ! bird malaria parasite created_by: louis creation_date: 2009-06-04T08:17:35Z [Term] id: IDOMAL:0001231 name: Plasmodium yoelii def: "An African rodent parasite, often used as a model." [KL:KL] is_a: IDOMAL:0000127 ! subgenus Plasmodium relationship: has_role IDOMAL:0001267 ! rodent malaria parasite created_by: louis creation_date: 2009-06-04T08:17:35Z [Term] id: IDOMAL:0001232 name: human haemoglobin def: "A protein composed of four globin chains and heme that gives red blood cells their characteristic color; its function is primarily to transport oxygen." [KL:KL] is_a: IDOMAL:0001233 ! human host protein created_by: louis creation_date: 2009-06-04T08:31:19Z [Term] id: IDOMAL:0001233 name: human host protein def: "A protein that is naturally found in humans." [KL:KL] is_a: IDOMAL:0001068 ! host protein created_by: louis creation_date: 2009-06-04T11:07:32Z [Term] id: IDOMAL:0001234 name: wild type haemoglobin def: "The haemoglobin that is comprised of two alpha and two beta chains encoded by the corresponding wild type genes." [KL:KL] is_a: IDOMAL:0001232 ! human haemoglobin created_by: louis creation_date: 2009-06-04T11:11:46Z [Term] id: IDOMAL:0001235 name: variant haemoglobin def: "Any haemoglobin that is comprised of at least one chain encoded by a corresponding non-wild type gene." [KL:KL] is_a: IDOMAL:0001232 ! human haemoglobin created_by: louis creation_date: 2009-06-04T11:11:46Z [Term] id: IDOMAL:0001236 name: haemoglobin S def: "A variant haemoglobin with a substitution of a valine for glutamine at position 57 in the beta chain." [KL:KL] synonym: "HbS" EXACT [] synonym: "Sickle cell haemoglobin" EXACT [] is_a: IDOMAL:0001235 ! variant haemoglobin relationship: realizes IDOMAL:0000538 ! resistance due to red cell polymorphism created_by: louis creation_date: 2009-06-04T11:18:18Z [Term] id: IDOMAL:0001237 name: haemoglobin E def: "A commonest variant haemoglobin in the world with a substitution of a lysine for glutamine at position 26 in the beta chain." [KL:KL] is_a: IDOMAL:0001235 ! variant haemoglobin relationship: realizes IDOMAL:0000538 ! resistance due to red cell polymorphism created_by: louis creation_date: 2009-06-04T11:18:18Z [Term] id: IDOMAL:0001238 name: haemoglobin C def: "A variant haemoglobin with a substitution of a glutamate for lysine at position 6 in the beta chain." [KL:KL] is_a: IDOMAL:0001235 ! variant haemoglobin relationship: realizes IDOMAL:0000538 ! resistance due to red cell polymorphism created_by: louis creation_date: 2009-06-04T11:18:18Z [Term] id: IDOMAL:0001239 name: thalassaemia-related haemoglobin def: "Any variant haemoglobin with an aminoacid substitution in either alpha or beta chain leading to the disease thalassaemia when in homozygous state." [KL:KL] is_a: IDOMAL:0001235 ! variant haemoglobin created_by: louis creation_date: 2009-06-04T11:18:18Z [Term] id: IDOMAL:0001240 name: human glucose-6-phosphate dehydrogenase def: "The first enzyme of the hexose monophosphate shunt whose deficiency leads, among others, to innate resistance to malaria." [KL:KL] synonym: "G6PD" EXACT [] is_a: IDOMAL:0001233 ! human host protein created_by: louis creation_date: 2009-06-04T11:26:46Z [Term] id: IDOMAL:0001241 name: condition def: "A realizable dependent continuant that inheres in substances." [ISBN:newdbxref "SNAP and SPAN: Towards Dynamic Spatial Ontology"] created_by: louis creation_date: 2009-06-29T01:46:09Z [Term] id: IDOMAL:0001242 name: clinical feature def: "Any condition of the human malaria host that is often the result of a disease." [KL:KL] is_a: IDOMAL:0000093 ! condition of malaria host created_by: louis creation_date: 2009-06-29T01:49:15Z [Term] id: IDOMAL:0001243 name: incidence of malaria def: "Prevalence over a stated time period independent of whether the disease resulted from a new infection or not." [KL:KL] synonym: "period prevalence of malaria" RELATED [] is_a: IDOMAL:0000351 ! quality of host population created_by: louis creation_date: 2009-06-04T11:49:59Z [Term] id: IDOMAL:0001244 name: airport malaria def: "A case of malaria in or near an airport in a non-malarious area transmitted by a mosquito imported by plane from an endemic region." [KL:KL] is_a: IDOMAL:0000578 ! imported malaria created_by: louis creation_date: 2009-06-04T12:11:33Z [Term] id: IDOMAL:0001245 name: transfusion malaria def: "Malaria cases resulting from the transfusion of blood taken from an infected individual." [KL:KL] is_a: IDOMAL:0000272 ! induced malaria created_by: louis creation_date: 2009-06-04T12:13:01Z [Term] id: IDOMAL:0001246 name: disease vector population def: "A given population of disease vectors in a specific area." [KL:KL] is_a: IDOMAL:0001254 ! population created_by: louis creation_date: 2009-06-04T01:39:54Z [Term] id: IDOMAL:0001247 name: embryonal stage def: "The first developmental stage that immediately follows fertilization of the egg." [KL:KL] is_a: IDOMAL:0000612 ! Anopheles developmental stage created_by: louis creation_date: 2009-06-04T03:34:16Z [Term] id: IDOMAL:0001248 name: first instar larval stage def: "The second developmental stage, immediately following the embryo stage upon moulting." [KL:KL] is_a: IDOMAL:0000639 ! larval stage created_by: louis creation_date: 2009-06-04T03:34:16Z [Term] id: IDOMAL:0001249 name: second instar larval stage def: "The developmental stage following the first instar larval stage." [KL:KL] is_a: IDOMAL:0000639 ! larval stage created_by: louis creation_date: 2009-06-04T03:34:16Z [Term] id: IDOMAL:0001250 name: third instar larval stage def: "The developmental stage following the third instar larval stage." [KL:KL] is_a: IDOMAL:0000639 ! larval stage created_by: louis creation_date: 2009-06-04T03:34:16Z [Term] id: IDOMAL:0001251 name: fourth instar larval stage def: "The last developmental stage before sclerotization and formation of the pupa." [KL:KL] is_a: IDOMAL:0000639 ! larval stage created_by: louis creation_date: 2009-06-04T03:34:16Z [Term] id: IDOMAL:0001252 name: pupal stage def: "The stage during which the larva transforms into an adult." [KL:KL] is_a: IDOMAL:0000612 ! Anopheles developmental stage created_by: louis creation_date: 2009-06-04T03:34:16Z [Term] id: IDOMAL:0001253 name: adult stage def: "The winged and last stage of development." [KL:KL] synonym: "imaginal stage" BROAD [] is_a: IDOMAL:0000612 ! Anopheles developmental stage created_by: louis creation_date: 2009-06-04T03:34:16Z [Term] id: IDOMAL:0001254 name: population def: "An aggregate of organisms." [IDO:509] is_a: IDOMAL:0000611 ! object aggregate created_by: louis creation_date: 2009-06-05T02:38:25Z [Term] id: IDOMAL:0001255 name: human population def: "A collection of human beings." [KL:KL] is_a: IDOMAL:0001254 ! population created_by: louis creation_date: 2009-06-05T02:39:12Z [Term] id: IDOMAL:0001256 name: immune human def: "A human organism that is protected against infectious disease by either specific or non-specific mechanisms." [KL:KL] is_a: IDOMAL:0000604 ! human created_by: louis creation_date: 2009-06-07T05:41:33Z [Term] id: IDOMAL:0001257 name: non-immune human def: "A human organism that is not protected against infectious disease by either specific or non-specific mechanisms." [KL:KL] is_a: IDOMAL:0000604 ! human created_by: louis creation_date: 2009-06-07T05:41:33Z [Term] id: IDOMAL:0001258 name: malaria-caused severe anaemia def: "One of three distinctive clinical syndromes in cases of P. falciparum malaria that are delineated by a series of criteria that have been put forward by the WHO." [KL:KL] is_a: IDOMAL:0000271 ! severe malaria created_by: louis creation_date: 2009-06-07T05:43:56Z [Term] id: IDOMAL:0001259 name: malaria-caused respiratory distress def: "One of three distinctive clinical syndromes in cases of P. falciparum malaria that are delineated by a series of criteria that have been put forward by the WHO." [KL:KL] is_a: IDOMAL:0000271 ! severe malaria created_by: louis creation_date: 2009-06-07T05:43:56Z [Term] id: IDOMAL:0001260 name: alpha thalassaemia-related haemoglobin def: "Any variant haemoglobin with an aminoacid substitution in the alpha chain leading to the disease alpha thalassaemia when in homozygous state." [KL:KL] is_a: IDOMAL:0001239 ! thalassaemia-related haemoglobin relationship: realizes IDOMAL:0000538 ! resistance due to red cell polymorphism created_by: louis creation_date: 2009-06-09T12:17:47Z [Term] id: IDOMAL:0001261 name: beta thalassaemia-related haemoglobin def: "Any variant haemoglobin with an aminoacid substitution in the beta chain leading to the disease beta thalassaemia when in homozygous state." [KL:KL] is_a: IDOMAL:0001239 ! thalassaemia-related haemoglobin relationship: realizes IDOMAL:0000538 ! resistance due to red cell polymorphism created_by: louis creation_date: 2009-06-09T12:17:47Z [Term] id: IDOMAL:0001262 name: malaria vector population def: "A given population of malaria vectors in a specific area." [KL:KL] is_a: IDOMAL:0001246 ! disease vector population created_by: louis creation_date: 2009-06-09T12:23:18Z [Term] id: IDOMAL:0001263 name: Plasmodium brazilianum def: "A protozoan species found in New World monkeys of the family Cebidae in northern South America and Panama, which can cause mild malaria in humans." [medilexicon.com:Plasmodium_brazilianum, medilexicon.com:Plasmodiumbrazilianum] is_a: IDOMAL:0000127 ! subgenus Plasmodium relationship: has_role IDOMAL:0001269 ! monkey malaria parasite created_by: louis creation_date: 2009-06-09T12:30:30Z [Term] id: IDOMAL:0001264 name: Plasmodium inui def: "A malarial parasite of Old World monkeys that occurs in isolated pockets throughout the Celebes, Indonesia, Malaysia, and the Philippines." [INIST-CNRS:2087\,_35400007582225.0110] is_a: IDOMAL:0000127 ! subgenus Plasmodium relationship: has_role IDOMAL:0001269 ! monkey malaria parasite created_by: louis creation_date: 2009-06-09T12:34:22Z [Term] id: IDOMAL:0001265 name: Plasmodium schwetzi def: "A parasite causing malaria to chimpazees and gorillas." [KL:KL] is_a: IDOMAL:0000127 ! subgenus Plasmodium relationship: has_role IDOMAL:0001269 ! monkey malaria parasite created_by: louis creation_date: 2009-06-09T12:37:02Z [Term] id: IDOMAL:0001266 name: Plasmodium simium def: "A parasite causing malaria infections in Saimiri boliviensis boliviensis monkeys." [KL:KL] is_a: IDOMAL:0000127 ! subgenus Plasmodium relationship: has_role IDOMAL:0001269 ! monkey malaria parasite created_by: louis creation_date: 2009-06-09T12:39:05Z [Term] id: IDOMAL:0001267 name: rodent malaria parasite def: "A malaria parasite naturally infecting rodents." [KL:KL] is_a: IDOMAL:0001286 ! malaria parasite created_by: louis creation_date: 2009-06-09T12:48:48Z [Term] id: IDOMAL:0001268 name: bird malaria parasite def: "A malaria parasite naturally infecting birds." [KL:KL] is_a: IDOMAL:0001286 ! malaria parasite created_by: louis creation_date: 2009-06-09T12:52:48Z [Term] id: IDOMAL:0001269 name: monkey malaria parasite def: "A malaria parasite naturally infecting monkeys. The term monkey is used here in a wide sense, i.e. it includes apes (but not humans) as primary reservoir." [KL:KL] is_a: IDOMAL:0001286 ! malaria parasite created_by: louis creation_date: 2009-06-09T12:54:06Z [Term] id: IDOMAL:0001270 name: Vinckeia def: "A subgenus of Plasmodium." [KL:KL] is_a: IDOMAL:0000126 ! Plasmodium created_by: louis creation_date: 2009-06-09T12:59:05Z [Term] id: IDOMAL:0001271 name: Plasmodium chabaudi def: "An African rodent parasite, often used as a model." [KL:KL] is_a: IDOMAL:0001270 ! Vinckeia relationship: has_role IDOMAL:0001267 ! rodent malaria parasite created_by: louis creation_date: 2009-06-09T01:00:35Z [Term] id: IDOMAL:0001272 name: nematode def: "An organsim that taxonomically belongs to the nematodes or roundworms (Phylum Nematoda), one of the most common phyla of animals, with over 80,000 different described species of which over 15,000 are parasitic." [KL:KL] is_a: IDOMAL:0000343 ! biotic created_by: louis creation_date: 2009-06-09T01:18:59Z [Term] id: IDOMAL:0001273 name: Romanomermis culicivorax def: "A nematode living in slow-moving freshwater, whose larval stages parasitize mosquito larvae." [KL:KL] is_a: IDOMAL:0001272 ! nematode relationship: agent_in IDOMAL:0000916 ! introduction of Romanomermis culicivorax relationship: has_role IDOMAL:0001277 ! mosquito parasite created_by: louis creation_date: 2009-06-09T01:19:25Z [Term] id: IDOMAL:0001274 name: vertebrate def: "Any member of the subphylum Vertebrata, chordates with backbones or spinal columns." [KL:KL] is_a: IDOMAL:0000343 ! biotic created_by: louis creation_date: 2009-06-09T01:22:06Z [Term] id: IDOMAL:0001275 name: fish def: "A fish is any aquatic vertebrate animal that is typically ectothermic (or cold-blooded), covered with scales, and equipped with two sets of paired fins and several unpaired fins. Fish are abundant in the sea and in fresh water, with species being known from mountain streams (e.g., char and gudgeon) as well as in the deepest depths of the ocean (e.g., gulpers and anglerfish)." [Wikipedia:fish] is_a: IDOMAL:0001274 ! vertebrate created_by: louis creation_date: 2009-06-09T01:25:38Z [Term] id: IDOMAL:0001276 name: Gambusia affinis def: "The mosquitofish (Gambusia affinis) is a species of freshwater fish, also commonly known simply by its generic name, gambusia, although such usage is ambiguous. It is sometimes called the western mosquitofish, to distinguish it from the eastern mosquitofish (G. holbrooki). It is a member of the family Poeciliidae of order Cyprinodontiformes. The genus name 'gambusia' is derived from the Cuban Spanish term 'gambusino', meaning useless." [Wikipedia:Mosquitofish] is_a: IDOMAL:0001278 ! larvivorous fish created_by: louis creation_date: 2009-06-09T01:27:54Z [Term] id: IDOMAL:0001277 name: mosquito parasite def: "Any organsim that parasitizes mosquitoes." [KL:KL] is_a: IDOMAL:0000995 ! parasite created_by: louis creation_date: 2009-06-09T01:30:42Z [Term] id: IDOMAL:0001278 name: larvivorous fish def: "A fish that feeds on mosquito larvae." [KL:KL] is_a: IDOMAL:0001275 ! fish relationship: agent_in IDOMAL:0000918 ! introduction of larvivorous fish created_by: louis creation_date: 2009-06-09T01:32:06Z [Term] id: IDOMAL:0001279 name: annual fish def: "Annual fishes are species that belong to the family Cyprinodontidae and which complete their life cycles within a year, their eggs requiring a dry period to develop fully." [KL:KL] is_a: IDOMAL:0001278 ! larvivorous fish created_by: louis creation_date: 2009-06-09T01:51:35Z [Term] id: IDOMAL:0001280 name: Nothobranchius guentheri def: "An larvivorous annual fish." [KL:KL] is_a: IDOMAL:0001279 ! annual fish created_by: louis creation_date: 2009-06-09T01:54:42Z [Term] id: IDOMAL:0001281 name: Cynolebias whitei def: "An larvivorous annual fish." [KL:KL] is_a: IDOMAL:0001279 ! annual fish created_by: louis creation_date: 2009-06-09T01:54:42Z [Term] id: IDOMAL:0001282 name: prodromal stage def: "The events occurring 2 to 3 days before the first malarial paroxysm during which the patient experiences mild symptoms that include malaise, fatigue, lassitude, a desire to stretch the limbs, headache, dizziness, pain in different areas of the body, anorexia, nausea and slight fever." [KL:KL] is_a: IDOMAL:0001054 ! process of malaria host relationship: realizes IDOMAL:0000518 ! generic clinical manifestation of malaria created_by: louis creation_date: 2009-06-09T03:06:16Z [Term] id: IDOMAL:0001283 name: general therapeutic procedure def: "A general therapeutic procedure applied for malaria." [KL:KL] is_a: IDOMAL:0000959 ! process of malaria created_by: louis creation_date: 2009-06-17T03:00:50Z [Term] id: IDOMAL:0001284 name: chemotherapy def: "The use of defined chemical agents to treat or control disease." [KLXX:KL] is_a: IDOMAL:0001283 ! general therapeutic procedure created_by: louis creation_date: 2009-06-17T03:03:45Z [Term] id: IDOMAL:0001285 name: malaria prophylaxis drug def: "A drug that is commonly used for malaria prophylaxis but usually not for its treatment." [KL:KL] is_a: IDOMAL:0000202 ! antimalarial drug created_by: louis creation_date: 2009-06-29T11:03:33Z [Term] id: IDOMAL:0001286 name: malaria parasite def: "A parasite causing malaria." [KL:KL] synonym: "malaria pathogen" EXACT [] is_a: IDOMAL:0000995 ! parasite created_by: louis creation_date: 2009-06-29T11:48:19Z [Term] id: IDOMAL:0001287 name: G6PD deficiency def: "An inherited condition that results in a deficiency in glucose-6-phosphate dehydrogenase." [KL:KL] is_a: IDOMAL:0000346 ! quality of host relationship: realizes IDOMAL:0000538 ! resistance due to red cell polymorphism created_by: louis creation_date: 2009-06-29T12:05:02Z [Term] id: IDOMAL:0001288 name: ovalocytosis def: "Ovalocytosis is an inherited condition in which a person's red blood cells, which are supposed to be round, instead have a slightly oval or elliptical shape." [Wikipedia:ovalocytosis] synonym: "hereditary elliptocytosis" EXACT [] is_a: IDOMAL:0000346 ! quality of host relationship: realizes IDOMAL:0000538 ! resistance due to red cell polymorphism created_by: louis creation_date: 2009-06-29T12:05:02Z [Term] id: IDOMAL:0001289 name: coma def: "A coma is a profound state of unconsciousness." [Wikipedia:coma] is_a: IDOMAL:0001242 ! clinical feature created_by: louis creation_date: 2009-06-29T03:02:07Z [Term] id: IDOMAL:0001290 name: unrousable coma def: "A coma persisting for at least 30 minutes after a convulsion." [KL:KL] is_a: IDOMAL:0001289 ! coma created_by: louis creation_date: 2009-06-29T03:03:12Z [Term] id: IDOMAL:0001291 name: domestic behaviour def: "The fact that an endophilic species rests inside the house after the meal." [KL:KL] is_a: IDOMAL:0001013 ! quality of vector created_by: louis creation_date: 2009-06-30T11:58:13Z [Term] id: IDOMAL:0001292 name: wild behaviour def: "The fact that an exophilic species will never go indoors." [KL:KL] is_a: IDOMAL:0001013 ! quality of vector created_by: louis creation_date: 2009-06-30T11:58:13Z [Term] id: IDOMAL:0001293 name: intermediate behaviour def: "The fact that an endophilic species will go outdoors for resting after the meal." [KL:KL] is_a: IDOMAL:0001013 ! quality of vector created_by: louis creation_date: 2009-06-30T11:58:13Z [Term] id: IDOMAL:0001294 name: vectorial capacity def: "In vector-borne infections such as malaria, the vectorial capacity is a concept analogous to the contact rate in directly-transmitted diseases. It is, thus, a function of (a) the vector's density in relation to its vertebrate host, (b) the frequency with which it takes blood meals on the host species, (c) the duration of the latent period in the vector, and (d) the vector's life expectancy." [Babylon:vectorial capacity] is_a: IDOMAL:0001013 ! quality of vector created_by: louis creation_date: 2009-06-30T12:02:22Z [Term] id: IDOMAL:0001295 name: vector competence def: "The ability of a vector to acquire a pathogen and to successfully transmit it to another susceptible host." [KL:KL] is_a: IDOMAL:0001013 ! quality of vector created_by: louis creation_date: 2009-06-30T12:02:22Z [Term] id: IDOMAL:0001296 name: cleavage by proteases def: "Protein molecules are cleaved into large peptides by proteinases (also called endopeptidases)." [ISBN:0-412-40180-0] is_a: IDOMAL:0002153 ! vector metabolic process relationship: part_of IDOMAL:0002058 ! protein catabolism [Term] id: IDOMAL:0001297 name: cleavage by serine proteases def: "The hydrolysis of peptide bonds by a class of peptidases which are characterised by the presence of a serine residue in the active center of the enzyme." [ISBN:0-412-40180-0] is_a: IDOMAL:0001296 ! cleavage by proteases [Term] id: IDOMAL:0001298 name: cleavage by esterases def: "The cleavage of the lipids that are contained in mosquitoes' meal by enzymes, such as carboxylesterases, acetylesterases, arylesterases, that are present in the midgut of adult female mosquitoes." [ISBN:0-412-40180-0] is_a: IDOMAL:0002153 ! vector metabolic process relationship: part_of IDOMAL:0002060 ! lipid catabolism [Term] id: IDOMAL:0001299 name: cleavage by carbohydrases def: "The cleavage of glycosidic linkages by specific enzymes, carbohydrases." [ISBN:0-412-40180-0] is_a: IDOMAL:0002153 ! vector metabolic process relationship: part_of IDOMAL:0002059 ! carbohydrate catabolism [Term] id: IDOMAL:0001300 name: cleavage by peptidases def: "The large peptides are progressively shortened by peptidases (more specifically called exopeptidases)." [ISBN:0-412-40180-0] is_a: IDOMAL:0002153 ! vector metabolic process relationship: part_of IDOMAL:0002058 ! protein catabolism [Term] id: IDOMAL:0002000 name: mating def: "The sequence of events that begins with the response of one individual to another of opposite sex and ends with insemination and parting. Mating often is proceded by swarming or other forms of epigamic behaviour." [ISBN:0-85199-313-3] is_a: IDOMAL:0002141 ! adult behavioural process relationship: part_of IDOMAL:0002160 ! reproduction [Term] id: IDOMAL:0002001 name: spatiotemporal region def: "Spacetime and spatiotemporal region [span:SpatiotemporalRegion] entities are entities in their own rights which exist independently of any entities which can be located at them. This view of spacetime can be called \"absolutist\" or \"the container view\". In BFO, the class processual context [span:ProcessualContext] allows for a so-called relational view of spacetime, that is to say, a view according to which spatiotemporality is a matter of relative location between entities and not a matter of being tied to spacetime. In BFO, the bridge between these two views is secured through the fact that instances of processual context [span:ProcessualContext] are too spatiotemporal entities." [SPAN:spatiotemporal region "http://www.ifomis.org/bfo/1.1/span#SpatiotemporalRegion"] created_by: Pantelis creation_date: 2009-07-19T11:01:44Z [Term] id: IDOMAL:0002002 name: fiat process part of malaria vector def: "The fiat process part occuring in a malaria host." [KL:KL] is_a: IDOMAL:0002223 ! fiat process part created_by: Pantelis creation_date: 2009-07-19T11:47:15Z [Term] id: IDOMAL:0002003 name: flight orientation def: "The nervous arcs through which co-ordination is effected lie in the thoracic ganglia." [ISBN:0-412-11490-9] is_a: IDOMAL:0002002 ! fiat process part of malaria vector relationship: part_of IDOMAL:0002078 ! flight [Term] id: IDOMAL:0002004 name: adult feeding behaviour def: "Two modes of feeding have been distinguished in male mosquitoes and one additional mode in females: water ingestion, nectar feeding and, for females only, blood feeding." [ISBN:0-412-40180-0, ISBN:0-85199-313-3] comment: Important aspects of the feeding behaviour of any mosquito species include (i) the identity of the vertebrate species on which it feeds in nature, (ii) whether its host range is restricted or unrestricted, (iii) the quantitative distribution of its feeds between host species in particular localities. is_a: IDOMAL:0002141 ! adult behavioural process [Term] id: IDOMAL:0002005 name: water ingestion def: "A small volume of water is imbibed and passed into the midgut." [ISBN:0-412-40180-0] is_a: IDOMAL:0002145 ! food ingestion relationship: part_of IDOMAL:0002004 ! adult feeding behaviour [Term] id: IDOMAL:0002007 name: exploratory phase def: "The first phase of the blood feeding; from time of alighting on the host to the time the stylets start to penetrate the skin." [ISBN:0-412-40180-0] is_a: IDOMAL:0002061 ! phase of supplementary feeding is_a: IDOMAL:0002310 ! adult female feeding behaviour relationship: part_of IDOMAL:0000637 ! mosquito bite relationship: part_of IDOMAL:0002015 ! interrupted feeding relationship: part_of IDOMAL:0002050 ! single feeding [Term] id: IDOMAL:0002008 name: probing phase def: "The phase of the blood feeding from first penetration of the skin to the first appearance of blood in the fascicle and cessation of palpal vibrations." [ISBN:0-412-40180-0] is_a: IDOMAL:0002061 ! phase of supplementary feeding is_a: IDOMAL:0002310 ! adult female feeding behaviour relationship: part_of IDOMAL:0000637 ! mosquito bite relationship: part_of IDOMAL:0002015 ! interrupted feeding relationship: part_of IDOMAL:0002050 ! single feeding relationship: preceded_by IDOMAL:0002007 ! exploratory phase relationship: preceded_by IDOMAL:0002028 ! exploration and examination of the body surface [Term] id: IDOMAL:0002009 name: imbibing phase def: "The phase of the blood feeding from first appearance of blood in the fascicle to the start of withdrawal." [ISBN:0-412-40180-0] is_a: IDOMAL:0002061 ! phase of supplementary feeding is_a: IDOMAL:0002310 ! adult female feeding behaviour relationship: part_of IDOMAL:0000637 ! mosquito bite relationship: part_of IDOMAL:0002015 ! interrupted feeding relationship: part_of IDOMAL:0002050 ! single feeding relationship: preceded_by IDOMAL:0002008 ! probing phase [Term] id: IDOMAL:0002010 name: withdrawal phase def: "The phase of the blood feeding from first straightening of the forelegs to complete removal of the stylets from the skin." [ISBN:0-412-40180-0] is_a: IDOMAL:0002061 ! phase of supplementary feeding is_a: IDOMAL:0002310 ! adult female feeding behaviour relationship: part_of IDOMAL:0000637 ! mosquito bite relationship: part_of IDOMAL:0002015 ! interrupted feeding relationship: part_of IDOMAL:0002050 ! single feeding relationship: preceded_by IDOMAL:0002009 ! imbibing phase [Term] id: IDOMAL:0002011 name: mixed meal def: "A meal acquired from two or more hosts, which may have been of the same species (single-species mixed meal) or different species (multi-species mixed meal)." [ISBN:0-85199-313-3] is_a: IDOMAL:0002015 ! interrupted feeding [Term] id: IDOMAL:0002012 name: simple meal def: "A blood meal resulting from a single feed. It may be complete or, as a result of interruption, incomplete." [ISBN:0-85199-313-3] is_a: IDOMAL:0002050 ! single feeding [Term] id: IDOMAL:0002013 name: supplementary meal def: "A second, third or yet further blood meal acquired in a single gonotrophic cycle through supplementary feeding." [ISBN:0-85199-313-3] relationship: part_of IDOMAL:0002016 ! supplementary feeding [Term] id: IDOMAL:0002014 name: multiple feeding def: "During a single gonotrophic cycle, the female takes more than one blood meal. Multiple feeding involves multiple host contacts." [ISBN:0-85199-313-3] is_a: IDOMAL:0002004 ! adult feeding behaviour [Term] id: IDOMAL:0002015 name: interrupted feeding def: "Acquisition of a blood meal in two or more parts, the mosquito having left its host while only partly fed, due to disturbance, and having resumed feeding soon afterwards on the same or another host." [ISBN:0-85199-313-3] is_a: IDOMAL:0002014 ! multiple feeding [Term] id: IDOMAL:0002016 name: supplementary feeding def: "Acquisition of additional blood meals after the first during a single gonotrophic cycle, independently of interruption due to disturbance, the feedings being separated by intervals of several hours to a day or more." [ISBN:0-85199-313-3] is_a: IDOMAL:0002014 ! multiple feeding [Term] id: IDOMAL:0002017 name: regulation of food intake in adults def: "The control of feeding and distribution of food within the gut by integrated responses of the peripheral sensilla, central nervous system and, probably, the stomatogastric system. Feeding generally terminates in response to mechanical stimulation caused by swelling of the gut." [ISBN:0-412-40180-0] is_a: IDOMAL:0002442 ! regulation of biological process relationship: part_of IDOMAL:0002186 ! adult nutrition [Term] id: IDOMAL:0002018 name: regulation of sugar intake def: "The regulation of the sugar intake in mosquitoes using chemosensilla and sugar receptors." [ISBN:0-412-40180-0] is_a: IDOMAL:0002017 ! regulation of food intake in adults [Term] id: IDOMAL:0002019 name: regulation of destination and volume def: "When mosquitoes drink, two control processes are involved: one regulates the destination of the fluid the other regulates the volume that is imbibed." [ISBN:0-412-40180-0] is_a: IDOMAL:0002017 ! regulation of food intake in adults [Term] id: IDOMAL:0002020 name: regulation of blood intake def: "Female mosquitoes gorge on blood when it is applied by capillary tube to the unsheathed fascicle or offered through an artificial membrane. Whether stimulation of just the larbal sensilla with blood is sufficient to induce drinking is not known, but certainly stimulation of both larbal and cibarial sensilla is sufficient." [ISBN:0-412-40180-0] is_a: IDOMAL:0002017 ! regulation of food intake in adults [Term] id: IDOMAL:0002021 name: host seeking def: "The sequence of behaviour patterns exhibited by mosquitoes responding to hosts over a distance. Host-seeking behaviour terminates once feeding is initiated and blood ingestion begins. For each species, host-finding activity is exhibited during one or more periods in the diel." [ISBN:0-12-473276-3, ISBN:0-85199-313-3] is_a: IDOMAL:0002141 ! adult behavioural process [Term] id: IDOMAL:0002022 name: activation def: "Activation is the first response to host cues; it is the initial response in a sequence of behaviours that ends with arrival at the host." [ISBN:0-85199-313-3] comment: Mosquitoes can be activated by host cues at any time. Un-fed, resting females of some species will attack at any hour if disturbed in their shelters by intrusion of a host or stimulated by odour from a nearby host. Such opportunistic biting has been observed in nocturnal mosquitoes disturbed by day. The activation step is readily observed in the laboratory but has seldom been described from the field. relationship: part_of IDOMAL:0002021 ! host seeking [Term] id: IDOMAL:0002023 name: long-range approach def: "The navigation of the mosquitoes towards potential hosts through their responses to a variety of cues emanating from them. Some host cues are chemical and others are physical." [ISBN:0-85199-313-3] synonym: "long range orientation" RELATED [ISBN:0-85199-313-3] is_a: IDOMAL:0002002 ! fiat process part of malaria vector relationship: part_of IDOMAL:0002021 ! host seeking [Term] id: IDOMAL:0002024 name: pre-attack resting def: "The resting of females in their host's proximity after they had approached them and before making a final approach and feeding." [ISBN:0-85199-313-3] comment: This phenomenon is been described in some members of the Leucosphyrus Subgroup, in Anopheles dirus, in Anopheles gambie, Anopheles arabiensis, Culex quinquefasciatus. relationship: part_of IDOMAL:0002021 ! host seeking [Term] id: IDOMAL:0002025 name: short-range approach, alighting and exploration def: "The short-range approach to the host is assumed to start when cues other than host odour are first perceived by the mosquito.\nThe final stage of host finding; it comprises four steps." [ISBN:0-85199-313-3] comment: This phase of host finding may follow a long-range approach or, if arrival of a host avtivates a resting mosquito, it may start immediately after activation. relationship: part_of IDOMAL:0002021 ! host seeking relationship: preceded_by IDOMAL:0002023 ! long-range approach [Term] id: IDOMAL:0002026 name: short-range approach to the host def: "The first step of short-range approach, alighting and exploration; from the perception of cues by the mosquito to the approach of the host." [ISBN:0-85199-313-3] comment: Is assumed to start when cues other than host odour are first perceived by the mosquito. is_a: IDOMAL:0002002 ! fiat process part of malaria vector relationship: part_of IDOMAL:0002025 ! short-range approach, alighting and exploration [Term] id: IDOMAL:0002027 name: descent to the body surface and alighting def: "The second step of the short-range approach, alighting and exploration." [ISBN:0-85199-313-3] comment: Except in total darkness, visual responces may govern the final stage of flight into the presence of a potential host, but additional stimuli may be required before the mosquito alights on the host. is_a: IDOMAL:0002002 ! fiat process part of malaria vector relationship: part_of IDOMAL:0002025 ! short-range approach, alighting and exploration relationship: preceded_by IDOMAL:0002026 ! short-range approach to the host [Term] id: IDOMAL:0002028 name: exploration and examination of the body surface def: "In this step the mosquito walks over the body, rapidly tapping the surface with its labella, and it may fly from one body region to another in order to find a region of vascularized skin into which it can drive its stylets." [ISBN:0-85199-313-3] is_a: IDOMAL:0002002 ! fiat process part of malaria vector relationship: part_of IDOMAL:0002025 ! short-range approach, alighting and exploration relationship: preceded_by IDOMAL:0002027 ! descent to the body surface and alighting [Term] id: IDOMAL:0002029 name: digestion of food def: "The digestion of blood and nectar. The midgut is the principal organ of digestion, but dissaccharides ingested in nectar are at least partly hydrolysed in the crop by a salivary enzyme." [ISBN:0-412-40180-0] is_a: IDOMAL:0002002 ! fiat process part of malaria vector relationship: part_of IDOMAL:0002186 ! adult nutrition [Term] id: IDOMAL:0002031 name: regulation of digestive enzyme synthesis def: "The regulation of enzyme synthesis by the presence of blood in the midgut or not." [ISBN:0-412-40180-0] is_a: IDOMAL:0002442 ! regulation of biological process relationship: part_of IDOMAL:0002029 ! digestion of food [Term] id: IDOMAL:0002032 name: absorption of the products of digestion def: "For the female: digestion of blood proteins yields amino acids which are reconstituted in the mosquito's fat body as proteinaceous yolk. This is important for oogenesis. For both sexes: Plant juices provide an important energy source. They are the only food sources for males." [ISBN:0-412-40180-0] relationship: part_of IDOMAL:0002029 ! digestion of food relationship: preceded_by IDOMAL:0002072 ! production of digestive enzymes [Term] id: IDOMAL:0002033 name: formation of peritrophic matrix def: "The formation of a membrane which is deposited around the ingested blood mass." [ISBN:0-412-40180-0] synonym: "formation of peritrophic membrane" RELATED [ISBN:0-12-473276-3] is_a: IDOMAL:0002112 ! physiological process of malaria vector relationship: part_of IDOMAL:0002029 ! digestion of food [Term] id: IDOMAL:0002034 name: vitellogenesis def: "The process of yolk formation." [ISBN:0-412-40180-0] is_a: IDOMAL:0002112 ! physiological process of malaria vector relationship: part_of IDOMAL:0002160 ! reproduction [Term] id: IDOMAL:0002035 name: vitellogenin synthesis def: "The formation of vitellogenin in the fat body. It is synthesized first as precursors which undergo proteolytic cleavage into two or more subunits." [ISBN:0-412-40180-0] comment: Vitellogenin was first detected by immunofluorescence onr hour after feeding, and vitellogenin seretion granules were observed at the cell membrane within three hours. is_a: IDOMAL:0002112 ! physiological process of malaria vector relationship: part_of IDOMAL:0002034 ! vitellogenesis [Term] id: IDOMAL:0002036 name: copulation def: "The act of sexual intercourse, during which the genitalia are engaged and the aedeagus inserted, and semen is passed to the female. It usually lasts a few seconds." [ISBN:0-85199-313-3] comment: In some species the process of copulation may last for many minutes. synonym: "coitus" RELATED [ISBN:0-85199-313-3] synonym: "sexual union" RELATED [ISBN:0-85199-313-3] is_a: IDOMAL:0002141 ! adult behavioural process relationship: part_of IDOMAL:0002000 ! mating [Term] id: IDOMAL:0002037 name: internalization of vitellogenin def: "Developing oocytes accumulate proteinaceous yolk by internalizing large amounts of circulating vitellogenin." [ISBN:0-412-40180-0] is_a: IDOMAL:0002002 ! fiat process part of malaria vector relationship: part_of IDOMAL:0002034 ! vitellogenesis [Term] id: IDOMAL:0002038 name: pre-mating coupling def: "The process occurring when a male first responds to a female, seizing her and establishing genital contact." [ISBN:0-85199-313-3] relationship: part_of IDOMAL:0002000 ! mating [Term] id: IDOMAL:0002039 name: excretion def: "Excretion is the process of waste products of metabolism and other non-useful materials getting out of the body." [KL:KL] comment: This term is used in two senses: broadly, for all eliminatory processes apart from defaecation, and more narrowly for the elimination of nitrogenous compounds. is_a: IDOMAL:0002112 ! physiological process of malaria vector [Term] id: IDOMAL:0002040 name: diuresis def: "The rapid production of urine containing principally water and salts." [ISBN:0-412-40180-0] is_a: IDOMAL:0002151 ! adult excretion [Term] id: IDOMAL:0002041 name: secretion of tubular fluid def: "The release of the unmodified secretion of the Malpighiann tubules." [ISBN:0-412-40180-0] is_a: IDOMAL:0002040 ! diuresis [Term] id: IDOMAL:0002042 name: excretion of tubular fluid def: "The tubular fluid is expelled as urine. Tubular fluids are the unmodified secretion of the Malpighian tubules." [ISBN:0-412-40180-0] is_a: IDOMAL:0002040 ! diuresis [Term] id: IDOMAL:0002043 name: resorption of tubular fluid def: "The tubular fluid enters the pylorus from where some may be move forwards for resorption in the midgut." [ISBN:0-412-40180-0] relationship: part_of IDOMAL:0002042 ! excretion of tubular fluid [Term] id: IDOMAL:0002044 name: production of urine def: "The portion of the tubular fluid that is not absorbed in the hindgut and is moved posteriorly to the rectum where it is modified producing urine." [ISBN:0-412-40180-0] is_a: IDOMAL:0002042 ! excretion of tubular fluid [Term] id: IDOMAL:0002045 name: urine def: "The completed excretory fluid as discharged to the exterior." [ISBN:0-412-40180-0] is_a: IDOMAL:0002047 ! excreta relationship: participates_in IDOMAL:0002044 ! production of urine [Term] id: IDOMAL:0002046 name: voiding of nitrogenous wastes def: "During the first day after feeding, deamination of amino acids produces excess nitrogen which is voided in the form of low molecular weight nitrogenous metabolites." [ISBN:0-412-40180-0] is_a: IDOMAL:0002151 ! adult excretion [Term] id: IDOMAL:0002047 name: excreta def: "Nitrogenous waste including uric acid, urea and ammonium ion, usually discharged in a semi-solid state but sometimes in the urine." [ISBN:0-412-40180-0] is_a: IDOMAL:0001034 ! abiotic relationship: participates_in IDOMAL:0002046 ! voiding of nitrogenous wastes [Term] id: IDOMAL:0002048 name: defaecation def: "The processes that rid the mosquito body of undigested food residues and other discarded products of the midgut." [ISBN:0-412-40180-0] comment: Excretion and defaecation can be distinguished visually because the excreta, coloured white or pale yellow by the uric acid, appear first and the dark brown or black faeces, coloured by haematin, appear later; however, there is some overlap. is_a: IDOMAL:0002151 ! adult excretion [Term] id: IDOMAL:0002049 name: faeces def: "Undigested food residues and other discarded products of the midgut." [ISBN:0-412-40180-0] is_a: IDOMAL:0002047 ! excreta relationship: participates_in IDOMAL:0002048 ! defaecation [Term] id: IDOMAL:0002050 name: single feeding def: "During a single gonotrophic cycle, the female takes only one blood meal." [ISBN:0-85199-313-3] is_a: IDOMAL:0002004 ! adult feeding behaviour [Term] id: IDOMAL:0002051 name: adult drinking def: "The fluid intake due to the activity of the cibarial and pharyngeal pumps." [ISBN:0-412-40180-0] is_a: IDOMAL:0002004 ! adult feeding behaviour relationship: part_of IDOMAL:0002086 ! nectar intake [Term] id: IDOMAL:0002052 name: labellar response def: "The separation of the labellar lobes following stimulation by sugar of sensilla on the outer surface of the labella." [ISBN:0-412-40180-0] is_a: IDOMAL:0002301 ! response to sugar solution relationship: part_of IDOMAL:0002086 ! nectar intake [Term] id: IDOMAL:0002053 name: proboscis response def: "The searching movements made with the proboscis when the tarsi are stimulated by sugar." [ISBN:0-412-40180-0] is_a: IDOMAL:0002301 ! response to sugar solution relationship: part_of IDOMAL:0002086 ! nectar intake [Term] id: IDOMAL:0002054 name: fertilization (sensu Anophelinae) def: "The union of male and female gametes and formation of a zygote in anopheline vectors." [ISBN:0-85199-313-3] is_a: IDOMAL:0002112 ! physiological process of malaria vector relationship: preceded_by IDOMAL:0002000 ! mating [Term] id: IDOMAL:0002055 name: aerobic glycolysis def: "The major pathway by which carbohydrates are degraded in insects for energy release." [ISBN:0-412-40180-0] is_a: IDOMAL:0002153 ! vector metabolic process relationship: part_of IDOMAL:0002059 ! carbohydrate catabolism [Term] id: IDOMAL:0002056 name: b-oxidation def: "The energy contained within fatty acid molecules is made available by b-oxidation of the fatty acid." [ISBN:0-412-40180-0] is_a: IDOMAL:0002153 ! vector metabolic process relationship: part_of IDOMAL:0002060 ! lipid catabolism [Term] id: IDOMAL:0002057 name: receptor-mediated endocytosis def: "The vitellogenin molecules bind to vitellogenin receptors located in coated pits on the oolemma and become internalized when the pits bud-off to form coated vesicles." [ISBN:0-412-40180-0] relationship: part_of IDOMAL:0002037 ! internalization of vitellogenin [Term] id: IDOMAL:0002058 name: protein catabolism def: "The breakdown into simpler components of a protein." [ISBN:0-412-40180-0] is_a: IDOMAL:0002456 ! catabolic process [Term] id: IDOMAL:0002059 name: carbohydrate catabolism def: "The hydrolysis of the carbohydrates that are contained in the mosquito's meal." [ISBN:0-412-40180-0] is_a: IDOMAL:0002456 ! catabolic process [Term] id: IDOMAL:0002060 name: lipid catabolism def: "The hydrolysis of lipids of mosquitoes' meals by specific enzymes." [ISBN:0-412-40180-0] is_a: IDOMAL:0002456 ! catabolic process [Term] id: IDOMAL:0002061 name: phase of supplementary feeding def: "The steps of a second, third or yet further meal acquired in a single gonotrophic cycle." [ISBN:0-85199-313-3] relationship: part_of IDOMAL:0002016 ! supplementary feeding [Term] id: IDOMAL:0002062 name: sugar feeding def: "The feeding on sugar." [XOX:XOXO] is_a: IDOMAL:0002004 ! adult feeding behaviour created_by: elvira creation_date: 2008-03-25T11:24:00Z [Term] id: IDOMAL:0002063 name: sensory coupling def: "The process of energy absorption from a physical stimulus by a sensillum and its transmission to sensory neurons." [ISBN:0-85199-313-3 "The biology of mosquitos A.N. Clements pp. 78"] is_a: IDOMAL:0002125 ! nervous system process relationship: part_of IDOMAL:0002221 ! reception of physical stimuli created_by: Pantelis creation_date: 2009-07-08T09:28:28Z [Term] id: IDOMAL:0002064 name: restricted feeding behaviour def: "Behaviour displayed by mosquitoes that feed on a few host species only, while in habitats in which a wide range of potential hosts is present." [ISBN:0-85199-313-3] is_a: IDOMAL:0002004 ! adult feeding behaviour [Term] id: IDOMAL:0002065 name: retraction of peritrophic matrix def: "In both culicines and anophelines, peritrophic membrane that is secreted in the enterior midgut slowly retracts and twists, forming a plug between the anterior medgut and stomach. A similar plug forms between the stomach and hindgut." [ISBN:0-412-40180-0] synonym: "retraction of peritrophic membrane" RELATED [ISBN:0-12-473276-3] is_a: IDOMAL:0002033 ! formation of peritrophic matrix [Term] id: IDOMAL:0002066 name: response to toxin def: "A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxin stimulus." [GO:0009636] synonym: "detoxification response" NARROW [] synonym: "toxin resistance" RELATED [] synonym: "toxin susceptibility/resistance" RELATED [] is_a: IDOMAL:0002134 ! response to chemical stimulus created_by: elvira creation_date: 2007-12-11T10:53:00Z [Term] id: IDOMAL:0002067 name: secretion of peritrophic matrix in adults def: "All midgut columnal cells secrete the substance of the membrane which is deposited around the ingested blood mass." [ISBN:0-412-40180-0] synonym: "secretion of peritrophic membrane in adults" RELATED [ISBN:0-12-473276-3] is_a: IDOMAL:0002033 ! formation of peritrophic matrix [Term] id: IDOMAL:0002068 name: secretion of peritrophic matrix in larvae def: "The membrane is secreted by a narrow band of cells at the anterior end of the mindgut and is formed as a continuous tube." [ISBN:0-412-40180-0] synonym: "secretion of peritrophic membrane in larvae" RELATED [ISBN:0-12-473276-3] is_a: IDOMAL:0002112 ! physiological process of malaria vector relationship: part_of IDOMAL:0002187 ! larval nutrition [Term] id: IDOMAL:0002069 name: collecting def: "Is the feeding mode most common used by mosquito larvae." [ISBN:0-412-40180-0] is_a: IDOMAL:0002182 ! larval feeding behaviour [Term] id: IDOMAL:0002070 name: distention of midgut def: "Immediately after feeding the midgut is hugely distended and for the next hour it is engaged in diuresis." [ISBN:0-412-40180-0] is_a: IDOMAL:0002112 ! physiological process of malaria vector relationship: part_of IDOMAL:0002029 ! digestion of food [Term] id: IDOMAL:0002071 name: organelle synthesis in midgut cells def: "A few hours after the distention of mindgut a phase of organelle synthesis occurs when additional ribosomes and endoplasmic reticulum are synthesized and organized." [ISBN:0-412-40180-0] is_a: IDOMAL:0002002 ! fiat process part of malaria vector relationship: part_of IDOMAL:0002029 ! digestion of food relationship: preceded_by IDOMAL:0002070 ! distention of midgut [Term] id: IDOMAL:0002072 name: production of digestive enzymes def: "After the organelle synthesis it follows a phase of production of digestive enzymes and absorption of the products of digestion." [ISBN:0-412-40180-0] is_a: IDOMAL:0002002 ! fiat process part of malaria vector relationship: part_of IDOMAL:0002029 ! digestion of food relationship: preceded_by IDOMAL:0002071 ! organelle synthesis in midgut cells [Term] id: IDOMAL:0002073 name: insemination def: "In culicines, the deposition of spermatozoa and secretions of the male accessory glands in the female's bursa inseminalis and the subsequent passage of spermatozoa into one or more spermathecal capsules. In anophelines, the transfer of sperm into the female's spermathecal duct (probably), and deposition of a mating plug in the vagina." [ISBN:0-85199-313-3] relationship: part_of IDOMAL:0002269 ! sexual refractoriness [Term] id: IDOMAL:0002074 name: assembly in station-keeping swarm def: "The males of a number of diptera taxa aggregate in aerials swarms over conspicuous objects or 'swarm markers'. Conspecific females individually fly to these swarms, but little is known of the responses that take them there. At the assembly stations where male and female insects meet, the females usually are recognized by vision, and among insects that form aerial swarms the eyes of the male are specially developed." [ISBN:0-85199-313-3] comment: Among some families of Culicimorpha, including the Culicidae, the eyes of males are not especially developed but certain auditory organs are, and the detection of females depends upon hearing. In these flies, the verticillate antennae and highly developed Johnston's organs mediate a sensitivity to the flight tone of conspecific females.\nStation-keeping swarms are formed by the members of certain families of Diptera, Ephemeroptera and Trichoptera, and to a lesser extend by representatives of the Hymenoptera and a few other insect orders. The assembly station is attended by both sexes, but usually the males fly there for long periods whareas the females remain only long enough to mate(Sivinski amd Petersson, 1997). is_a: IDOMAL:0002077 ! formation of assembly is_a: IDOMAL:0002256 ! hearing response during mating is_a: IDOMAL:0002258 ! response to visual stimulus during mating relationship: part_of IDOMAL:0002270 ! swarming [Term] id: IDOMAL:0002075 name: formation of assembly near vertebrate host def: "Males of a number of species of Aedes and Mansonia assemble around the warm-blooded hosts on which the females feed, and attempt to couple with virgin females that also respond to the host." [ISBN:0-85199-313-3] comment: These males have a well developed Johnston's organ, and it is likely that in most of these species the females' wing tone is an important cue for the final orientation of males to a female.\nWe may note here the assembly of males at the feeding site of a non-blood-sucking mosquito. Females of the autogenous species Malaya leei hover over a procession of ants on a tree trunk and, from time to time, settle to obtain regutgitated fluid from an ant. Males often appeared behind the hovering females and mated with them , completing the act within few seconds. is_a: IDOMAL:0002077 ! formation of assembly is_a: IDOMAL:0002256 ! hearing response during mating relationship: part_of IDOMAL:0002270 ! swarming [Term] id: IDOMAL:0002076 name: formation of assembly at emergence site def: "In a few species, sexually mature males aggregate at the emergence sites, congregating on or near the water surface. Depending on species, they respond to pupae, to emerging females, to newly emerged females or to teneral females. In most of these species the male antennae are modified. Such males do not respond to the female wing-beat tone. In species in which respond to pupae, the male forelegs are modified. In all of these species, the males beome sexually competent only after inversion of their terminalia, which takes a period of hours, but females are sexually receptive at the time of emergence." [ISBN:0-85199-313-3] comment: Species that exhibit this kind of behaviour are, Opifex fuscus, Deinocerites cancer, Culiseta inornata, and the genuses Aedes and Psorophora. is_a: IDOMAL:0002077 ! formation of assembly relationship: part_of IDOMAL:0002270 ! swarming [Term] id: IDOMAL:0002077 name: formation of assembly def: "The process of gathering at different sites as part of the mating process." [ISBN:0-85199-313-3] is_a: IDOMAL:0002002 ! fiat process part of malaria vector relationship: part_of IDOMAL:0002254 ! senses and flight response during mating [Term] id: IDOMAL:0002078 name: flight def: "The movement of adult mosquitoes in the air." [ISBN:0-85199-313-3] comment: Little is known about the mosquito aerodynamics, but there is a wealth of information on the behavioural responses of flying mosquitoes and the role of flight in mosquito biology. is_a: IDOMAL:0002455 ! adult locomotion [Term] id: IDOMAL:0002079 name: response to chemical cue def: "The chemical stimuli are organic and inorganic constituents of host odour. Mosquitos respond to some of these kairomones at a distance from the host as they are carried by the wind, and they respond to some at very short range as they are carried in convection currents." [ISBN:0-85199-313-3] is_a: IDOMAL:0002134 ! response to chemical stimulus relationship: part_of IDOMAL:0002023 ! long-range approach [Term] id: IDOMAL:0002080 name: response of flying mosquito to visible object def: "The insect's natural habitat can evoke a response because of the produced visual images." [ISBN:0-85199-313-3] is_a: IDOMAL:0002315 ! response to visual stimuli relationship: part_of IDOMAL:0002078 ! flight [Term] id: IDOMAL:0002081 name: response to isolated object def: "Mosquitoes variably approach or avoid visible objects. The responses of mosquitoes to artificial objects have important implications for trap design, but their biological significance is uncertain." [ISBN:0-85199-313-3] is_a: IDOMAL:0002080 ! response of flying mosquito to visible object [Term] id: IDOMAL:0002082 name: response to barrier and boundary def: "Mosquitoes (night-flying) may alter their flight paths when confronted with barriers, even when the barriers contain apertures large enough for their passage. Observations showed associations between mosquito flight paths and conspicuous features of the landscape." [ISBN:0-85199-313-3] is_a: IDOMAL:0002080 ! response of flying mosquito to visible object [Term] id: IDOMAL:0002083 name: flight capacity def: "Mosquitoes species differ in flight capacity, but to speak of an individual species flight range is incorrect because the distances are greatly affected by weather conditions (i.e. wind) and ecological variables." [ISBN:0-85199-313-3] is_a: IDOMAL:0001013 ! quality of vector [Term] id: IDOMAL:0002084 name: migration def: "Is a persistent and straightened-out movement effected by the animal's own locomotory exertions or by its active embarkation on a vehicle such as wind. Migration depends on some temporary inhibiotion of station-keeping responses, but promotes their eventual disinhibition and recurrence." [ISBN:0-85199-313-3] is_a: IDOMAL:0002141 ! adult behavioural process [Term] id: IDOMAL:0002085 name: persistent locomotion def: "Continuous flight." [ISBN:0-85199-313-3] is_a: IDOMAL:0002002 ! fiat process part of malaria vector relationship: part_of IDOMAL:0002078 ! flight [Term] id: IDOMAL:0002086 name: nectar intake def: "The steps needed for the intake of nectar and other plant sources." [ISBN:0-412-40180-0] is_a: IDOMAL:0002145 ! food ingestion [Term] id: IDOMAL:0002087 name: sugar metabolism def: "Feeding on nectar and other plant juices provides an immediate energy source and permits the formation of carbohydrate and lipid reserves." [ISBN:0-85199-313-3] is_a: IDOMAL:0002153 ! vector metabolic process relationship: part_of IDOMAL:0002400 ! feeding on plant sugar [Term] id: IDOMAL:0002088 name: formation of carbohydrate and lipid reserves def: "Feeding on sugar, and, for females, on blood, leads to accumulations of fat and glycogen." [ISBN:0-85199-313-3] comment: Experiments with females of Aedes sollicitans, Aedes taeniorhynchus and Aedes aegypti shoed that a hormonal mechanism determined wether ingested sugar was converted to glycogen or fat. Females of Aedes sollicitans that ingested a large bloodmeal after a period of starvation fully replenished their stores of glycogen and triacylglycerol. is_a: IDOMAL:0002087 ! sugar metabolism [Term] id: IDOMAL:0002089 name: release and conservation of energy from sugar def: "Three major processes are involved in the release of energy from sugars: (i) glycolysis, which ends in the production of pyruvate; (ii) oxidation in the tricarboxylic acid (TCA) cycle; and (iii) further oxidation in the respiratory chain (oxidative phosphorylation)." [ISBN:0-85199-313-3] is_a: IDOMAL:0002087 ! sugar metabolism [Term] id: IDOMAL:0002090 name: accumulation and use of the carbohydrate and lipid reserve def: "The carbohydrate and lipid reserves present in most mosquitoes at emergence are insufficient for more than a few days' life and, for all males and the females of many species, must be replenished by feeding on plant sugars. A portion of the digestion products from blood meals in converted to glycogen and lipids, the proportion varying with species and with size of female." [ISBN:0-85199-313-3] comment: It has been suggested that some anophelines use the first blood meal primarily for the synthesis of maternal reserves. Sufficient is known to indicate that in general the metabolic pathways of culicids conform with those of other insects. is_a: IDOMAL:0002087 ! sugar metabolism [Term] id: IDOMAL:0002091 name: process of oogenesis def: "The oogonia in the end chamber or germanium become differentiated into oocytes and nurse cells. As the oocytes move backwards they become surrounded by the follicle cells of somatic origin, which compose the hind part of the germarium, and each oocyte in its follicle forms an egg chamber of the vitellarium. As the oocyte grows the cells finally arrange themselves in a single layer." [ISBN:0-41211-490-9, ISBN:0-85199-313-3] is_a: IDOMAL:0002002 ! fiat process part of malaria vector relationship: part_of IDOMAL:0002160 ! reproduction [Term] id: IDOMAL:0002092 name: formation of ovarian follicles def: "During mosquito embryogenesis pole cells form after cleavage energids have entered the posterior periplasm with its polar granules. The pole mirgrate in to two groups and settled in the 6th abdominal segment, where they become surrounded by mesodermal sheaths and form the gonad rudiments. The pole cells are now called primordial germ cells. By the 4th larval instar the ovaries are already distinct and contain cell clusters within a matrix of smaller cells, the interstitial tissue. By the early pupal stage each ovary has reformed into a group of ovarioles. Later in the pupal stage each ovariole differentiate into a germarium amd a vitellarium compromising one, two or even three ovarian follicles." [ISBN:0-412-40180-0] is_a: IDOMAL:0002112 ! physiological process of malaria vector relationship: part_of IDOMAL:0002091 ! process of oogenesis [Term] id: IDOMAL:0002093 name: response to oviposition-aggregation pheromone def: "Gravid females of Culex quinquefasciatus and Cx tarsalis oviposit preferentially on water where already egg rafts have been laid." [ISBN:0-85199-313-3] comment: Similar apical droplets have been described from a number of species of Culex, Culiseta, Uranotaenia that lay their eggs in rafts. In Culex, apical droplets are known from pipiens, quinquefasciatus, stigmatosoma, tarsalis and erythrothorax of subgenus Culex and from apicalis of subgenus Neoculex. In Culiseta they are known from annulata and incidens of subgenus Culiseta, and longiareolata of subgenus Allotheobaldia. In Uranotaenia they are known from anhydor of subgenus Pseudoficalbia. Chemical analysis revealed the oviposition aggregation pheromone of Culex quinquefasciatus to be the (-)-(5R,6S) stereoisomer of the fatty-acid lactone 6-acetoxy-5-hexadecanolide. is_a: IDOMAL:0002309 ! response to chemical cue during pre-oviposition stage and oviposition [Term] id: IDOMAL:0002094 name: previtellogenic phase def: "The period during which follicles separate from the germania, cell types become visibly distinct , the oocytes become competent to incorporate vitellogenin, and a little growth occurs prior to entry into a resting stage." [ISBN:0-412-40180-0] is_a: IDOMAL:0002277 ! ovarian developmental stages according Troy et al. [Term] id: IDOMAL:0002095 name: initiation phase def: "The few hours immediately after a blood meal when follicle growth recommences, with the formation of additional microvilli and coated pits, and vitellogenin synthesis starts." [ISBN:0-412-40180-0] is_a: IDOMAL:0002277 ! ovarian developmental stages according Troy et al. [Term] id: IDOMAL:0002096 name: trophic phase def: "The main period of vitellogenin synthesis and incorporation with rapid oocyte growth, ending with the cessation of vitellogenin synthesis and formation of an intact endochorionic layer between oocyte and epithelial cells." [ISBN:0-412-40180-0] is_a: IDOMAL:0002277 ! ovarian developmental stages according Troy et al. [Term] id: IDOMAL:0002097 name: post-trophic phase def: "When the oocyte assumes its mature form and becomes surrounded by an unhardened chorion." [ISBN:0-412-40180-0] is_a: IDOMAL:0002277 ! ovarian developmental stages according Troy et al. [Term] id: IDOMAL:0002098 name: rRNA synthesis in oocyte and nurse cells def: "Histochemical studies combined with the use of radioactive tracers and electron microscopy have largely confirmed that there is active synthesis and emission of RNA from the nucleus, and thence from the nucleus of the oocyte to the cytoplasm. Some of the proteins of the egg are synthetized in the nurse cells and follicular cells." [ISBN:0-412-11490-9] comment: This process is seen in Aedes. is_a: IDOMAL:0002112 ! physiological process of malaria vector relationship: part_of IDOMAL:0002361 ! process of ovulation [Term] id: IDOMAL:0002099 name: follicle growth and development def: "The process of the four developmental phases, from the primary follicles to the mature form of the oocyte." [ISBN:0-412-40180-0] comment: The four phases are: (1) prvitellogenic phase, (2) initiation phase, (3) trophic phase and (4) post-trophic phase. is_a: IDOMAL:0002358 ! growth relationship: part_of IDOMAL:0002091 ! process of oogenesis [Term] id: IDOMAL:0002100 name: chorion formation def: "The chorion is the part of the egg shell that is secreted before oviposition by the follicular epithelium, a maternal tissue." [ISBN:0-412-40180-0] is_a: IDOMAL:0002112 ! physiological process of malaria vector relationship: part_of IDOMAL:0002091 ! process of oogenesis [Term] id: IDOMAL:0002101 name: secretion of the chorion def: "Secretion occurs in two phases and results in formation of the two layers of the chorion, the endochorion and exochorion. Use of the terms 'vitelline membrane' or 'vitelline envelope' for the endochorion is inappropriate." [ISBN:0-412-40180-0] relationship: part_of IDOMAL:0002100 ! chorion formation [Term] id: IDOMAL:0002102 name: hardening and darkening of the chorion def: "At oviposition the eggs are soft and white but within an hour the chorion begins to darken and harden. Colour development is uniform over the entire surface of the egg, and after 4h the egg shell looks black and is relatively firm. Superficially at least this process resembles sclerotization." [ISBN:0-412-40180-0] comment: The definition concerns the eggs of Aedes aegytpi.\nUntanned chorions separated from newly laid eggs were colourless, but when chorions were isolated after they had hardened and darkened naturally , the endochorion appeared brownish-grey and the exochorion colourless. relationship: part_of IDOMAL:0002100 ! chorion formation [Term] id: IDOMAL:0002103 name: activation while ranging flight def: "Flying in the absense of resource cues." [ISBN:0-85199-313-3] is_a: IDOMAL:0002022 ! activation [Term] id: IDOMAL:0002104 name: activation while settled on a support def: "Mosquitoes can be activated by host cues at any time. Unfed, resting females of some species will attack at any hour if disturbed in their shelters by intrusion of a host or stimulated by odour from a nearby host. Such opportunistic biting has been observed in nocturnal mosquitoes disturbed by day. The activation step is readily observed in the laboratory but has seldom been described from the field." [ISBN:0-85199-313-3] is_a: IDOMAL:0002022 ! activation [Term] id: IDOMAL:0002105 name: take-off def: "If the stimulus is sight of a moving host, the activated mosquito, may fly directly to the host." [ISBN:0-85199-313-3] relationship: part_of IDOMAL:0002104 ! activation while settled on a support [Term] id: IDOMAL:0002106 name: sustained flight def: "If the stimulus is olfactory but there is no air movement, as can happen in the laboratory the response is kinetic, i.e an increase in flight speed or frequency of turning." [ISBN:0-85199-313-3] relationship: part_of IDOMAL:0002104 ! activation while settled on a support [Term] id: IDOMAL:0002107 name: response to expired breath def: "Known kairomones include carbon dioxide, octenol, lactic acid and water vapour. Carbon dioxide activates mosquitoes and is used in odour-mediated anemotaxis. Octenol and lactic acid act additively and possibly in some instances synergistically with carbon dioxide." [ISBN:0-85199-313-3] is_a: IDOMAL:0002079 ! response to chemical cue [Term] id: IDOMAL:0002108 name: response to the skin odours def: "Aliphatic acids and other unidentified products of the skin surface serve as kairomones. Certain constituents or hydrolytic products of urine possibly also serve as kairomone." [ISBN:0-85199-313-3] is_a: IDOMAL:0002079 ! response to chemical cue [Term] id: IDOMAL:0002109 name: response to thermal stimulus def: "Mosquitoes can detect heat transfer from vertebrate hosts over short distances, and the manner of heat transfer to which they respond is the subject of the section." [ISBN:0-85199-313-3] is_a: GO:0050896 ! response to stimulus relationship: part_of IDOMAL:0002023 ! long-range approach [Term] id: IDOMAL:0002110 name: response to visual cue def: "The role of vision in host finding may differ between day- and night- flying species. Mosquitoes respond to host movement. Night-flying mosquitoes that were beleived to be ranging flight would alter their heading to fly towards inanimate physical objects. Mosquitos is proved that reponse to the length of colour in simple shaped objects." [ISBN:0-85199-313-3] comment: Little is known of the responses of mosquitoes to visual cues. is_a: IDOMAL:0002080 ! response of flying mosquito to visible object relationship: part_of IDOMAL:0002023 ! long-range approach relationship: realized_by IDOMAL:0002184 ! adult vision [Term] id: IDOMAL:0002111 name: response to aggregation volatile def: "Mosquitos have the ability to apprehend certain volatile host emanations in the air. Only if there is an air movement can they fly towards a distant odour source. If there is not an air movement the mosquitos are unable to orient themselves to the source of the volatiles." [ISBN:0-85199-313-3] is_a: IDOMAL:0002134 ! response to chemical stimulus relationship: part_of IDOMAL:0002023 ! long-range approach [Term] id: IDOMAL:0002112 name: physiological process of malaria vector def: "Those processes are specifically unique to the functioning of intergrated living units: cells, tissues, organs, organisms." [http://www.reactome.org] is_a: IDOMAL:0001059 ! process of malaria vector [Term] id: IDOMAL:0002113 name: muscular system process def: "The muscles of insects fall into two groups; the skeletal muscle forming bands across the articulations of the body wall, which serve to move one segment on another, and the visceral muscles which invest the internal organs." [ISBN:0-412-11490-9] is_a: IDOMAL:0002112 ! physiological process of malaria vector [Term] id: IDOMAL:0002114 name: locomotion def: "The assortment of movements of the mosquito." [ISBN:0-85199-313-3] is_a: IDOMAL:0002113 ! muscular system process [Term] id: IDOMAL:0002115 name: walking def: "The insect rests during walking on a supporting triangle, formed by the anterior and posterior limb on one side and the middle limb on the other, while it carries forward the other three legs." [ISBN:0-412-11490-9] is_a: IDOMAL:0002455 ! adult locomotion [Term] id: IDOMAL:0002116 name: coordination of walking def: "The nervous arcs through which co-ordination is effected lie in the thoracic ganglia. The fore leg acts as a tractor; the middle leg serves for support, lifting the body on its own side and together with the hind leg raising the posterior part of the body; the hind leg acts as a propulsor and also turns the body in the horizontal plane. The three legs forming the tripod for a time being are not lifted simultaneously but in the order: i)fore-leg ii)opposite middle leg iii)hind-leg." [ISBN:0-412-11490-9] is_a: IDOMAL:0002442 ! regulation of biological process relationship: part_of IDOMAL:0002115 ! walking [Term] id: IDOMAL:0002117 name: pupal diving def: "In order to dive, a pupa must partialy strenghthen the abdomen an simultaneously make a backward movementof the trumpet which breaks a its contact with the surface." [ISBN:0-85199-313-3] is_a: IDOMAL:0002178 ! pupal locomotion [Term] id: IDOMAL:0002118 name: pupal swimming def: "Only the paddles, powered by the abdominal muscles, function as propulsive organs. The rest of the body has no locomotory function other tham balancing forces of the paddle stroke." [ISBN:0-85199-313-3] is_a: IDOMAL:0002178 ! pupal locomotion [Term] id: IDOMAL:0002119 name: larval crawling def: "Some larvae walk by means of their thoracic legs in the same manner as adult forms; but they are often aided by provisional modifications of the abdomen." [ISBN:0-412-11490-9] is_a: IDOMAL:0002432 ! larval locomotion [Term] id: IDOMAL:0002120 name: larval swimming def: "Larvae use their abdominal muscles to cause a lateral flexure of the abdomen. The massive abdominal muscles that provide the power for larval locomotion persist through the pupal and pharate-adult stages." [ISBN:0-85199-313-3] is_a: IDOMAL:0002432 ! larval locomotion [Term] id: IDOMAL:0002121 name: gliding def: "The movement of adult mosquitoes in the air currents. Defined as slowly falling at less than 45 degrees from the horizontal." [ISBN:0-85199-313-3] is_a: IDOMAL:0002002 ! fiat process part of malaria vector relationship: part_of IDOMAL:0002078 ! flight [Term] id: IDOMAL:0002122 name: equilibrium during flight def: "The lower Diptera (Tipulids) have long thin abdomens and long legs which probably ensure their stabilityduring flight. In higher forms (Muscids) their wings-beats create a resultant force which is equal to or greater than the weight of the insect." [ISBN:0-412-11490-9] comment: Studied only in the Diptera. is_a: IDOMAL:0002002 ! fiat process part of malaria vector relationship: part_of IDOMAL:0002078 ! flight [Term] id: IDOMAL:0002123 name: reaction time def: "The period between stimulus and contraction." [ISBN:0-412-11490-9] synonym: "speed of muscular response" EXACT [] is_a: IDOMAL:0000092 ! temporal region [Term] id: IDOMAL:0002124 name: muscle contraction def: "An electrical stimulus of infinite duration must be of a certain threshold strength in order to produce a response in nerve or muscle. If the strength of stimulus is increased its duration may be shortened." [ISBN:0-412-11490-9] is_a: IDOMAL:0002113 ! muscular system process [Term] id: IDOMAL:0002125 name: nervous system process def: "The precise modulations of contractions of the individual muscles. When expressed together or in a specific sequence, these contractions embody the displacements in space that are interpreted as the expression of particular behaviors." [ISBN:0-12-473276-3, ISBN:0-85199-313-3] comment: Little is known of the functional anatomy of the mosquito nervous system. is_a: IDOMAL:0002112 ! physiological process of malaria vector [Term] id: IDOMAL:0002126 name: visceral nervous system def: "The part of the peripheral nervous system that acts as a control system, maintaining homeostasis in the body." [ISBN:0-412-11490-9] synonym: "sympathetic nervous system" RELATED [] is_a: IDOMAL:0002461 ! anatomical cluster relationship: participates_in IDOMAL:0002125 ! nervous system process [Term] id: IDOMAL:0002127 name: stomatogastric nervous system def: "Arises during embryonic development by an ingrowth from the dorsal wall of the stomodaeum which later requires connexion with the brain." [ISBN:0-412-11490-9] is_a: IDOMAL:0002460 ! anatomical system relationship: part_of IDOMAL:0002126 ! visceral nervous system [Term] id: IDOMAL:0002128 name: caudal sympathetic system def: "Innervates the sexual organs and the posterior segments of the gut is composed of nerves arising from the composite terminal ganglion of the abdomen. The mid-gut, the heart and the Malpighian tubes show continued movements after separation from the central nervous system. The control of these movements is attributed to peripheral ganglion cells; and it has been suggested that it is this autonomous peripheral system that should be called the sympathetic nervous system." [ISBN:0-412-11490-9] is_a: IDOMAL:0002460 ! anatomical system relationship: part_of IDOMAL:0002126 ! visceral nervous system [Term] id: IDOMAL:0002129 name: endocrine system process def: "The endocrine system is an integrated system of small organs that involve the release of extracellular signaling molecules known as hormones." [ISBN:0-412-11490-9] comment: Consists of: (i) modified nerve cells, (ii) neuro-haemal organs which are believed to serve as the sites at which the neurospecretory products escape into the blood-stream and (iii) independant organs of internal secretion derived from nests of cells which have been budded off the ectoderm in the region of the mouth part. is_a: IDOMAL:0002112 ! physiological process of malaria vector [Term] id: IDOMAL:0002130 name: sensory perception def: "The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal." [GO:0007600] is_a: IDOMAL:0002112 ! physiological process of malaria vector [Term] id: IDOMAL:0002131 name: vision def: "The sense by which the qualities of an object (as color, luminosity, shape, and size) constituting its appearance are perceived through a process in which light rays entering the eye are transformed by the retina into electrical signals that are transmitted to the brain via the optic nerve." [http:www.nlm.nih.gov] synonym: "sight" RELATED [http:www.nlm.nih.gov] is_a: IDOMAL:0002221 ! reception of physical stimuli [Term] id: IDOMAL:0002132 name: unrestricted feeding behaviour def: "Behaviour displayed by mosquitoes that feed on wider range of hosts, while in habitats in which a wide range of potential hosts is present." [ISBN:0-85199-313-3] is_a: IDOMAL:0002004 ! adult feeding behaviour [Term] id: IDOMAL:0002133 name: hearing def: "The waves of air pressure which we recognize as sounds may be perceived by insects by two quite different mechanism. The antennae of mosquitoes are mechanosensory transducers which in flight respond to drag forces and to gravitational forces, and in which the males at least are also sensitive to sound waves. Organs of hearing convert the energy of sound waves into electrical signals, and in this way resemble microphones." [ISBN:0-412-11490-9, ISBN:0-412-40180-0, ISBN:0-85199-313-3] is_a: IDOMAL:0002221 ! reception of physical stimuli [Term] id: IDOMAL:0002134 name: response to chemical stimulus def: "A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus." [GO:0042221] synonym: "response to chemical substance" EXACT [] is_a: GO:0050896 ! response to stimulus [Term] id: IDOMAL:0002135 name: response of gustatory sensilla def: "The perception of the qualities of sweet, sour, salt and bitter. Gustatory sensilla are uniporous hair or peg sensilla that respond to stimulating molecules in the liquid phase. In mosquitoes they are present on the legs and mouthparts, and the input from the various sensilla is intergrated centrally." [ISBN:0-412-11490-9, ISBN:0-85199-313-3] synonym: "taste" RELATED [] is_a: IDOMAL:0002134 ! response to chemical stimulus [Term] id: IDOMAL:0002136 name: response of olfactory sensilla def: "The sense of smell in insects is located chiefly in the antennae. The olfactory sensilla of mosquitoes compromise multiporous hair and peg sensilla on the antennal flagella and multiporous peg sensilla on the maxillary palps." [ISBN:0-412-11490-9, ISBN:0-85199-313-3] comment: The volitile compounds that have been tested for activity in these sensilla fall into 4 classes:\n1) Carbon Dioxide.\n2) Unsubstituted and substituded short-chain,aliphatic monocarboxylic acids.\n3) Essential oils.\n4) Attracttans. synonym: "smell" RELATED [] is_a: IDOMAL:0002134 ! response to chemical stimulus [Term] id: IDOMAL:0002137 name: behavioural process def: "The process of any action or reaction of a vector organism in response to external or internal stimuli." [KL:KL] is_a: IDOMAL:0002112 ! physiological process of malaria vector [Term] id: IDOMAL:0002138 name: regulation of adult behaviour def: "It is found that the behavioural activities of adult mosquitoes take place at particular times of day and night, which vary between species and the timing is controlled by endogeous or so-called circadian rythms, which are reset daily by the change from light to dark at sunset." [ISBN:0-412-40180-0] is_a: IDOMAL:0002442 ! regulation of biological process relationship: part_of IDOMAL:0002141 ! adult behavioural process [Term] id: IDOMAL:0002139 name: larval behavioural process def: "The analysis of the movements of the mosquito's larva into a series of reflexes or observed correlations between stimulus and response." [ISBN:0-412-11490-9] is_a: IDOMAL:0002137 ! behavioural process [Term] id: IDOMAL:0002140 name: pupal behavioural process def: "The analysis of the movements of the mosquito's pupa into a series of reflexes or observed correlations between stimulus and response." [ISBN:00412114909] is_a: IDOMAL:0002137 ! behavioural process [Term] id: IDOMAL:0002141 name: adult behavioural process def: "Any behavioral process during the adult stage of a vector organism." [KL:KL] is_a: IDOMAL:0002137 ! behavioural process [Term] id: IDOMAL:0002142 name: circulation def: "The circulation of the blood is maintained by a system of muscular pumps and fibro-muscular septa. The haemolymph has many functions. It provides the tissues that it bathes with nutrients and metabolic intermediates, and it provides a medium for the transport of their chemical wastes." [ISBN:0-412-11490-9, ISBN:0-412-40180-0] is_a: IDOMAL:0002112 ! physiological process of malaria vector [Term] id: IDOMAL:0002143 name: nutritional process def: "Oragnic material of almost every kind in nature serve as food for insects. The process of nutrition starts with the ingestion of food and ends with the digestion." [ISBN:0-412-11490-9, ISBN:0-412-40180-0] comment: The reproductive capacity of female mosquitoes is affected by their nutrition in both the larval and adult stages. is_a: IDOMAL:0002112 ! physiological process of malaria vector [Term] id: IDOMAL:0002144 name: saliva secretion def: "Is conducted mostly by the distal regions of the lateral lobes of the salivary gland. Median lobes played less part to the saliva secretion. The saliva that is injected as the mouthparts penetrate contains a substance that prevents haemostasis, the aggregation of blood platelets that is the host's firstdefence against the laceration of small blood vessels." [ISBN:0-412-40180-0] comment: The saliva is also the source of immunogens that are responsible for the characteristic skin reactions to mosquito bites. is_a: IDOMAL:0002112 ! physiological process of malaria vector relationship: part_of IDOMAL:0002186 ! adult nutrition relationship: part_of IDOMAL:0002187 ! larval nutrition [Term] id: IDOMAL:0002145 name: food ingestion def: "The process of taking a substance into the body through the mouth." [ISBN:0-85199-313-3] is_a: IDOMAL:0002002 ! fiat process part of malaria vector relationship: part_of IDOMAL:0002186 ! adult nutrition [Term] id: IDOMAL:0002146 name: respiration def: "The process with which oxygen is conveyed from the atmosphere to the tissues, and how the carbon dioxide resulting from oxidation in the tissues is eliminated." [ISBN:0-412-11490-9] is_a: IDOMAL:0002112 ! physiological process of malaria vector [Term] id: IDOMAL:0002147 name: adult respiration def: "The intake of oxygen in the adult mosquito." [ISBN:0-412-40180-0] is_a: IDOMAL:0002146 ! respiration [Term] id: IDOMAL:0002148 name: regulation of respiratory system def: "The regulation is done by pumping air by opening and closing spiracles." [ISBN:0-412-11490-9] comment: Studied in cockroach and flea. is_a: IDOMAL:0002442 ! regulation of biological process relationship: part_of IDOMAL:0002146 ! respiration [Term] id: IDOMAL:0002149 name: larval respiration def: "Larvae use an open respiratory system which impose limitations to the requirement for access to atmospheric oxygen. The mosquito larval tracheal system consist of two wide dorsal longitydinal trunks, two narrower lateral, and branches which run from them to all regions of the body." [ISBN:0-412-40180-0] comment: A pair of air sacs of unknown function is present near the junction of thorax and abdomen in certain species. is_a: IDOMAL:0002146 ! respiration [Term] id: IDOMAL:0002150 name: pupal respiration def: "The 1st abdominal spiracles open into the ventral air space, which is enclosed by the pupal mouthparts, wings and legs and which functions in pupal buoyancy." [ISBN:0-412-40180-0] comment: Mosquito pupae are the only insects that have only the anterior thoracic and the anterior abdominal spiracles functional. Most of the outer surface of the respiratory trumpet is hydrophilic, but the spiracular opening is surrounded by a ring of hydrophobic cuticle against which water forms a contact angle. is_a: IDOMAL:0002146 ! respiration [Term] id: IDOMAL:0002151 name: adult excretion def: "The processes that rid the adult mosquito body of unwanted substances and ensure homeostasis of the hemolymph under conditions of water and salt loading." [ISBN:0-412-40180-0] is_a: IDOMAL:0002039 ! excretion [Term] id: IDOMAL:0002152 name: larval excretion def: "The secretion and regulation of inorganic ions in larvae." [ISBN:0-412-40180-0] is_a: IDOMAL:0002039 ! excretion [Term] id: IDOMAL:0002153 name: vector metabolic process def: "All the chemical changes which the constituents of the vector undergo. These changes serve two purposes, growth on the one hand and the performance of the work on the other." [IB:IB] synonym: " vector metabolic process resulting in cell growth" NARROW [] synonym: " vector metabolism" BROAD [] synonym: " vector metabolism resulting in cell growth" EXACT [] is_a: IDOMAL:0002112 ! physiological process of malaria vector [Term] id: IDOMAL:0002154 name: chemical transformation def: "Changes in chemical composition of the body." [ISBN:0-412-11490-9] relationship: part_of IDOMAL:0002153 ! vector metabolic process [Term] id: IDOMAL:0002155 name: fat metabolism def: "Fat is the chief form in which energy is stored. It is usually present in greatest amounts in the mature larva before metamorphosis. At ordinary temperatures the fat may be a liquid oil or a crystalline solid." [ISBN:0-412-11490-9] is_a: IDOMAL:0002154 ! chemical transformation [Term] id: IDOMAL:0002156 name: carbohydrate metabolism def: "Sugar in the blood and tissues is probably the most readily available source of energy. Carbonhydrate is stored mainly in the fat body, in the form of glycogen. Other carbonhydrates are chitin of the cuticle and the mucopolysaccharides of the connective tissues and basement membranes." [ISBN:0-412-11490-9] is_a: IDOMAL:0002154 ! chemical transformation [Term] id: IDOMAL:0002157 name: protein metabolism def: "Proteins provide the chief structural elements of the muscles, glands and other tissues. A certain amount of protein is stored in the fat body and much is deaminated or converted into carbohydrate or fat and used for energy production." [ISBN:0-412-11490-9] is_a: IDOMAL:0002154 ! chemical transformation [Term] id: IDOMAL:0002158 name: pigment metabolism def: "Metabolism of pigments is usually connected with physiological processes and stimulated by some abiotic and biotic factors. However, pigment metabolism may be affected by food, and in relation to selection, they may also be affected by stubstances polluting the environment, which thus indirectly help the propagation of dark forms." [http://globalecology.stanford.edu] comment: Blood pigments are relatively rare in insects and their function is usually accessory to tracheal respiration, so that their intoxication has limited effects on the insect organism. is_a: IDOMAL:0002153 ! vector metabolic process [Term] id: IDOMAL:0002159 name: respiratory metabolism def: "The rate at which processes of oxidation take place in the living body, varies within wide limits." [ISBN:0-412-11490-9] comment: The values recorded depend upon muscular activity, external temperature, tissue growth, and a host of other factors. is_a: IDOMAL:0002153 ! vector metabolic process relationship: part_of IDOMAL:0002146 ! respiration [Term] id: IDOMAL:0002160 name: reproduction def: "Bisexual; the egg cell liberated by the female will develop only after the fusion with the spermatozoal cell set free by the male. The reproduction's physiology deals with the arrangements for the separation and ripening of these male and female gametes, and with the mechanisms by which they are brought together." [ISBN:0-412-11490-9] is_a: IDOMAL:0002112 ! physiological process of malaria vector [Term] id: IDOMAL:0002161 name: hormonal regulation def: "The hormonal involvement in the regulation of enzyme synthesis." [ISBN:0-412-40180-0] is_a: IDOMAL:0002031 ! regulation of digestive enzyme synthesis [Term] id: IDOMAL:0002162 name: adult energy metabolism def: "Energy metabolism starts when an insect ingests food, which supplies the fuel from which the chemical energy is liberated. Energy can be gained from lipids, carbohydrates, or proteins, but each one of these compounds cannot be used under every condition. The primary energy stores in insects are the fat body and the haemolymph." [ISBN:0-412-40180-0, ISBN:0-87081-411-7] is_a: IDOMAL:0002153 ! vector metabolic process [Term] id: IDOMAL:0002163 name: developmental process def: "A biological process whose specific outcome is the progression of an integrated living unit: a cell, tissue, organ, or organism over time from an initial condition to a later condition." [GO:isa_complete] is_a: IDOMAL:0002112 ! physiological process of malaria vector [Term] id: IDOMAL:0002164 name: moulting def: "Primarily a mechanism of growth, conditioned by the properties of the cuticle. There are two aspects to the problem of moulting; i) the initiation of the process of the growth and cuticle ii) the determination of those changes in form that occur during ecdysis. Moulting involves all parts of the body, whether supplied with nerves or not, at the same time. Each moult can be considered as a sequence of events." [ISBN:0-412-11490-9, ISBN:0-412-40180-0] is_a: IDOMAL:0002163 ! developmental process [Term] id: IDOMAL:0002165 name: deposition of the new cuticle def: "Little is known of the structure of mosquito larval cuticle other than that the abdomen it consists of a two-layered corrugated epicuticle, a then exocuticle and an endocuticle of some five lamellae. Pore canals are present." [ISBN:0-412-40180-0] synonym: "formation of cuticle" RELATED [ISBN:0421401800] relationship: part_of IDOMAL:0002164 ! moulting [Term] id: IDOMAL:0002166 name: hardening and darkening of cuticle def: "Three hours after larval-pupal ecdysis the epicuticle darkens. The outer seven lamellae of the procuticle which constitute the outer region of exocuticle darken shortly thereafter, and subsequently the epicuticle and outer exocuticle look like a single homogeneous layer. The colour of the pupal abdomen changes from white at ecdysis to grey after one hour and to dark brown after three hours." [ISBN:0-412-40180-0] relationship: part_of IDOMAL:0002165 ! deposition of the new cuticle [Term] id: IDOMAL:0002167 name: expansion of cuticle def: "Formation of pharate cuticle starts during the later stages of dissolution of the pupal cuticle. Seventeen hours after larval-pupal ecdysis small 3-layered plates are deposited just above the apical membrane of the epidermal cells, which bears minute microvilli at this stage. Addition of material at the edges of the plate leads to the formation of a continuous layer of outer epicuticle over the epidermal cells. By the pupal-adult ecdysis there are four lamellae." [ISBN:0-412-40180-0] relationship: part_of IDOMAL:0002165 ! deposition of the new cuticle [Term] id: IDOMAL:0002168 name: secretion of moulting fluid def: "Fifteen hours after larval-pupal ecdysis, apolysis starts. The epidermis separates from the pupal cuticle forming an apolysial space in which a small amount of apolysial fluid accumulates." [ISBN:0-412-40180-0] relationship: part_of IDOMAL:0002164 ! moulting [Term] id: IDOMAL:0002169 name: secretion of moulting hormone def: "The hormone from the neurosecretory cells of the brain activates the thoracic glands and causes them to secrete the moulting hormone. The thoracic glands requie the continued presence of the brain hormone until the \"critical period\", when mitosis has begun and there is an adequate supply of moulting hormone in the blood." [ISBN:0-412-11490-9] relationship: part_of IDOMAL:0002164 ! moulting [Term] id: IDOMAL:0002170 name: metamorphosis def: "A strikingly discontinuous change of form. The intermediate stages of development become apparent only under special circumstances. There are all degrees of such discontinuity.\nAs holometabolous insects mosquitoes undergo complete metamorphosis, developing through larval and pupal stages before reaching the adult state." [ISBN:0-412-11490-9, ISBN:0-412-40180-0] is_a: IDOMAL:0002163 ! developmental process [Term] id: IDOMAL:0002171 name: histological change def: "During moulting, even when unaccompanied by any striking change of form, there is much reconstruction in the epidermis. New cell divisions and the death and disolution of unwanted nuclei take place simultaneously." [ISBN:0-412-11490-9] relationship: part_of IDOMAL:0002170 ! metamorphosis [Term] id: IDOMAL:0002172 name: histolysis def: "At the present time it is agreed that there are great differences in different insects or in different organs of the same insect; and it is also agreed that the phagocytes are concerned only in removing cells which are already dead and in process of autolysis-although such cells may show little histological change." [ISBN:0-412-11490-9] comment: Controversary term. relationship: part_of IDOMAL:0002170 ! metamorphosis [Term] id: IDOMAL:0002173 name: diapause def: "A condition in which growth or development is suspended and physiological activity is diminished." [ISBN:0-412-11490-9] is_a: IDOMAL:0000711 ! condition of malaria vector [Term] id: IDOMAL:0002174 name: sexual behaviour def: "During the first or second day after emergence, a mosquito undergoes behavioural maturation when, due to the action of hormones and other substances that act on the nervous system, it becomes competent in sexual behaviour." [ISBN:0-85199-313-3] is_a: IDOMAL:0002141 ! adult behavioural process relationship: part_of IDOMAL:0002160 ! reproduction [Term] id: IDOMAL:0002175 name: male sexual responsiveness def: "Male mosquitos become sexually responsive to flying conspecific females 12-36h after emergence, by which time their terminalia have inverted and their antennal fibrilae have become either permanenrly erect or capable of temporary erection." [ISBN:0-85199-313-3] is_a: IDOMAL:0002174 ! sexual behaviour relationship: part_of IDOMAL:0002267 ! sexual responsiveness and refractoriness relationship: part_of IDOMAL:0002340 ! regulation of sexual behaviour [Term] id: IDOMAL:0002176 name: female sexual refractoriness def: "Observations of the coupling of force-mated or tethered females suggested that refractoriness is expressed through altered responses of the female terminalia to genital contact. Even if coupling occurs, it does not result in sperm transfer." [ISBN:0-85199-313-3] is_a: IDOMAL:0002174 ! sexual behaviour relationship: part_of IDOMAL:0002340 ! regulation of sexual behaviour [Term] id: IDOMAL:0002177 name: pre-oviposition behaviour def: "Is a form of foraging, and it includes responses to the environment at three hierarchical levels: the habitat, the patch or biotope, and the resource item." [ISBN:0-85199-313-3] is_a: IDOMAL:0002141 ! adult behavioural process relationship: precedes IDOMAL:0002427 ! egg laying behaviour [Term] id: IDOMAL:0002178 name: pupal locomotion def: "The pupae of almost all holometabolous insects are incapable of locomotion; instead the mosquito pupae swim and dive exceptionaly. Although they can swim strongly, they spend most of their time immobile at the water surface." [ISBN:0-85199-313-3] is_a: IDOMAL:0002114 ! locomotion [Term] id: IDOMAL:0002179 name: living at the water surface def: "Mosquito larvae have the usual internal organs of ion regulation and also they have four external balloon-like anal papillae, which are capable of ion uptake from very dilute solution. They are anatomically adapted for the specific characteristics of the water surface, notably the surface forces in the air-water interface. Mosquitoes (mostly Culidis) form part of the neuston-the assemblage of small to medium-sized organisms that live at the water surface." [ISBN:0-412-40180-0, ISBN:0-85199-313-3] comment: Factors that characterize the water surface: (i)surface tension and (ii)surface film.\nAquatic insects which live immediately under the water surface have access to two major resources:\n(i) They can obtain direct access to the atmosphere for respiration.\n(ii) They are in the immediate vicinity of food. is_a: IDOMAL:0002139 ! larval behavioural process [Term] id: IDOMAL:0002180 name: taxis def: "The movements of the larvae that are oriented directly towards or directly away from stimuli. Prefixes denote the nature of the stimulus. A taxis is positive if directed towards the source, and negative if directed away from it." [ISBN:0-85199-313-3] is_a: IDOMAL:0002139 ! larval behavioural process [Term] id: IDOMAL:0002181 name: larval kinesis def: "Unoriented movements made in response to particular stimuli. The strength of the response is related to intensity of stimulation. Kineses can have prefixes that denote the nature of the stimulus." [ISBN:0-85199-313-3] is_a: GO:0050896 ! response to stimulus relationship: part_of IDOMAL:0002139 ! larval behavioural process [Term] id: IDOMAL:0002182 name: larval feeding behaviour def: "The characteristic food resource of mosquito larvae is 'particular matter'. This includes aquatic microorganisms, such as bacteria, diatoms and algae, and also, as an important component, particles of detritus that are largely derived from decayed plant tissues." [ISBN:0-412-40180-0, ISBN:0-85199-313-3] comment: Divided into three activities:\n1)movement to a source of food.\n2)capture of food by behaviour appropriate to the food source.\n3)Coordination of the intricate mouthparts movements. is_a: IDOMAL:0002139 ! larval behavioural process relationship: part_of IDOMAL:0002187 ! larval nutrition [Term] id: IDOMAL:0002183 name: grooming def: "Larvae groom themselves by working their mouthparts over accessible parts of the body surface. After their use in feeding and grooming, the mouthparts themselves need to be cleaned, and structures that serve that function are present at the posterior end of the abdomen of the most larvae." [ISBN:0-85199-313-3] comment: To groom the abdomen, larvae bend themselves into a loop. The body part that is most often cleaned is the spiracular opening of the respiratory siphon. is_a: IDOMAL:0002139 ! larval behavioural process [Term] id: IDOMAL:0002184 name: adult vision def: "Adult mosquitos have two accurate and sensitive compound eyes. They have the capacity to resolve details of the spatial environment and so permit complex activities such as upwind flight and position holding in swarms. The compound eyes of the adult mosquito arise during the first larval instar as thickenings of the epidermis, called optic placodes, just anterior to the stemmata. The compound eyes of the mosquitoes have the capacity to resolve details of the spatial environment and so permit complex activities such as upwind flight and position holding swarms." [ISBN:0-85199-313-3] comment: Much remains to be discovered about connections between optic sensilla or ommatidia with the visual neuropiles in the optic lobes and the information from the neurons. is_a: IDOMAL:0002131 ! vision [Term] id: IDOMAL:0002185 name: larval vision def: "Simple structures which differ from the ocelli or single-lens eyes present in the adults of most orders and in the larvae of most non-holometabolous orders of insects." [ISBN:0-85199-313-3] comment: The larval visual organs are stemmata (lateral ocelli). is_a: IDOMAL:0002131 ! vision [Term] id: IDOMAL:0002186 name: adult nutrition def: "Both sexes require plant juices as an energy source. Female mosquitoes imbibe blood to obtain protein for ovary development." [ISBN:0-412-40180-0] comment: Toxorhynchitine females do NOT require blood for oogenesis. They feed only on plant juices. is_a: IDOMAL:0002143 ! nutritional process [Term] id: IDOMAL:0002187 name: larval nutrition def: "The uptake of food ranging from small particles to live invertebrates." [ISBN:0-412-40180-0] is_a: IDOMAL:0002143 ! nutritional process [Term] id: IDOMAL:0002188 name: blood feeding def: "A mode of feeding by females, in which the fascicle is deployed beyond the labella to penetrate the skin of the host, and a large volume of blood is imbibed and passed into the midgut. Blood feeding can be divided into four phases." [ISBN:0-412-40180-0\:newdbxref] is_a: IDOMAL:0002145 ! food ingestion is_a: IDOMAL:0002310 ! adult female feeding behaviour created_by: Pantelis creation_date: 2009-07-12T07:16:04Z [Term] id: IDOMAL:0002189 name: collecting-filtering def: "Is the removal of particles suspended in the water column or associated with the water surface." [ISBN:0-412-40180-0] is_a: IDOMAL:0002069 ! collecting [Term] id: IDOMAL:0002190 name: scraping def: "Is the removal and ingestion of the biofilm that abheres tightly to submerged plant and mineral surfaces, and also of the algae and stalked protists that adhere directly to such surfaces." [ISBN:0-412-40180-0] comment: Larvae of Aedes exhibit this feeding mode in rock pools and it is probably more widespread. is_a: IDOMAL:0002182 ! larval feeding behaviour [Term] id: IDOMAL:0002191 name: shredding def: "The gnawing and biting-off of small fragments of tissue, whether from plantsor dead invertebrates." [ISBN:0-412-40180-0] comment: Gnawing of leaves has been described in Culiseta inornata and Aedes triseriatus larvae. Culex bitaeniorhynchus larvae feed selectively on filamentous chlorophytes. Tripteroides use the shredding feeding mode and feed on dead invertebrates. is_a: IDOMAL:0002182 ! larval feeding behaviour [Term] id: IDOMAL:0002192 name: collecting-gathering def: "Is the resuspension and removal of particles deposited on or loosely attached to surfaces." [ISBN:0-412-40180-0] comment: It is found in many species of Aedes and in some species of Psorophora, Haemagogus and Wyeomyia. is_a: IDOMAL:0002069 ! collecting [Term] id: IDOMAL:0002193 name: predation def: "Some mosquito larvae seize and engulf other insects, and often of their own size. The prey is swallowed whole." [ISBN:0-412-40180-0] comment: Is observed in larvae of Toxorhynchites and of the subgenera Lutzia (of Culex), Mucidus (of Aedes) and Psorophora. Also larvae of a number of sebatine genera are facultative predators, as are larvae of Eretmapodites. is_a: IDOMAL:0002182 ! larval feeding behaviour [Term] id: IDOMAL:0002194 name: larval drinking def: "Mosquito larvae imbibe substantial volumes of water when feeding and also drink extensively in the absence of food." [ISBN:0-412-40180-0] is_a: IDOMAL:0002182 ! larval feeding behaviour [Term] id: IDOMAL:0002195 name: post-peak phase def: "Declining flow rate of urine production." [ISBN:0-412-40180-0] relationship: part_of IDOMAL:0002044 ! production of urine [Term] id: IDOMAL:0002196 name: peak phase def: "Very rapid flow in the first minutes after the blood meal." [ISBN:0-412-40180-0] relationship: part_of IDOMAL:0002044 ! production of urine [Term] id: IDOMAL:0002197 name: late phase def: "When the flow rate is slightly above the control level." [ISBN:0-412-40180-0] relationship: part_of IDOMAL:0002044 ! production of urine [Term] id: IDOMAL:0002198 name: larval growth alt_id: MOSBP:0000237 def: "Mosquito larvae pass through four instars. Growth is continuous throughout each instar, as can be seen in the progressive increase in size of the body regions that are covered with thin cuticle." [ISBN:0-412-40180-0] comment: The heavily sclerotized parts of the body, the cranium and respiratory siphon , increase in size immediately after ecdysis but this is a manifestation of earlier growth processes. Growth of the soft parts is not always isometric. is_a: IDOMAL:0002358 ! growth [Term] id: IDOMAL:0002199 name: larval instar def: "Mosquito larvae pass through four instar. Each instar is a stage of development but also growth." [ISBN:0-412-40180-0] is_a: IDOMAL:0002358 ! growth [Term] id: IDOMAL:0002200 name: apolysis def: "The retraction of the epidermis from the cuticle." [ISBN:0-412-40180-0] is_a: IDOMAL:0002164 ! moulting [Term] id: IDOMAL:0002201 name: ecdysis def: "The final stage of moulting. Shedding of what remains of the old cuticle." [ISBN:0-412-40180-0] relationship: part_of IDOMAL:0002164 ! moulting [Term] id: IDOMAL:0002202 name: larval-larval ecdysis def: "The ecdysis between any of the four larval instars." [ISBN:0-412-40180-0] comment: The epidermis can be seen to separate from the cuticle and to secrete new cuticle and bristles beneath it while the tracheal epithelium similarly retracts from the tracheal linings and secretes new cuticular lining around them. A mid-ventral ecdysial line is also found in many species. Movements of the head free it from the old cranium and the dorsal split extends back over the thorax so the peristaltic movements the larva is able to escape from the cast cuticle, sometimes in less than a minute. The old tracheal trunks have broken across just behind their connections to the non-functional spiracles in each segment. is_a: IDOMAL:0002201 ! ecdysis [Term] id: IDOMAL:0002203 name: larval-pupal ecdysis def: "The ecdysis between the larval and the pupal stage." [ISBN:0-412-40180-0] comment: This ecdysis is heralded by the appereance of the respiratory trumpets and palmate float setae of the pharate pupa as dark bodies beneath the larval cuticle. The larval trachea collapse at this time. The larval cuticle and tracheal linings are shed much as at previous ecdyses, and during this period the labial and maxillary palp disks are extruded from the peripodial cavities. is_a: IDOMAL:0002201 ! ecdysis [Term] id: IDOMAL:0002204 name: pupal-adult ecdysis def: "The emergence of the adult mosquito from the pupal cuticle." [ISBN:0-412-40180-0] synonym: "eclosion" RELATED [ISBN:0-412-40180-0] synonym: "emergence" RELATED [ISBN:0-412-40180-0] is_a: IDOMAL:0002201 ! ecdysis [Term] id: IDOMAL:0002205 name: imaginal disk development def: "The rudiments of some imaginal disks are present in newly hatched larvae and develop slowly during the larval stage; others appear as late as the 3rd instar. Each imaginal disk is first apparent as a plate of columnar epidermal cells which grows slowly with cell division. Increase in size of the imaginal disks occurs principally during the 4th instar, accompanied by numerous mitoses, and in most cases the disks are shaped only very approximately like the adult appendages at the time." [ISBN:0-412-40180-0] is_a: IDOMAL:0002171 ! histological change [Term] id: IDOMAL:0002206 name: development of the gonadal primordia def: "The development and differentiation of the gonads and primary sexual characters." [ISBN:0-412-40180-0] is_a: IDOMAL:0002171 ! histological change [Term] id: IDOMAL:0002207 name: development of the central nervous system def: "The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GO:0007417] synonym: "CNS development" EXACT [] is_a: IDOMAL:0002171 ! histological change is_a: IDOMAL:0002362 ! larval development [Term] id: IDOMAL:0002208 name: development of the compound eye def: "The development of the compound eyes proceeds in a sequence of events - first determination and cellular proliferation, then differentiation - which pass as waves across a region of the head epidermis, the 'prospective eye field', that will transform into the compound eye." [ISBN:0-412-40180-0] is_a: IDOMAL:0002171 ! histological change is_a: IDOMAL:0002362 ! larval development [Term] id: IDOMAL:0002209 name: metamorphosis of the alimentary canal def: "At metamorphosis some of the tissues that have endopolyploid nuclei undergo somatic reduction and cell divistion to yield a large number of small, apparently de-differentiated cells which are competent to form adult tissues." [ISBN:0-412-40180-0] is_a: IDOMAL:0002171 ! histological change [Term] id: IDOMAL:0002210 name: response of single-walled multiporous hair sensilla def: "They are sensitive to olfactory stimuli and occur abundantly on the antennal flagella. The hairs are pointed or blunt and arise without sockets." [ISBN:0-85199-313-3] comment: Most experimental work has been undertaken on Aedes aegypti, in which four distinct types of single-walled multiporous hair sensilla have been distinguished. synonym: "responses of A1 sensilla" RELATED [ISBN:0-85199-313-3] synonym: "responses of A2 sensilla" RELATED [ISBN:0-85199-313-3] synonym: "responses of trichoid sensilla" RELATED [ISBN:0-85199-313-3] is_a: IDOMAL:0002136 ! response of olfactory sensilla [Term] id: IDOMAL:0002211 name: responses of short blunt single-walled multiporous hair sensilla def: "When these sensilla are exposed to stimulating vapours, the excited neurones gave a phasic-tonic response. It seems likely that the short blunt single-walled multiporous hair sensila on female antennae are used in the location of oviposition sites." [ISBN:0-85199-313-3] is_a: IDOMAL:0002210 ! response of single-walled multiporous hair sensilla [Term] id: IDOMAL:0002212 name: responses of short pointed single-walled multiporous hair sensilla def: "These sensilla are stimulated by saturated C3 to C7 fatty acids at unspesific dosage rates. They respond also to ethyl propanoate." [ISBN:0-85199-313-3] is_a: IDOMAL:0002210 ! response of single-walled multiporous hair sensilla [Term] id: IDOMAL:0002213 name: responses of long pointed single-walled multiporous hair sensilla def: "These seensilla were perdominantly stimulated by C2 to C10 saturated straight-chain fatty acids. Their spontaneous activity was inhibited by volatile oils." [ISBN:0-85199-313-3] is_a: IDOMAL:0002210 ! response of single-walled multiporous hair sensilla [Term] id: IDOMAL:0002214 name: responses of blunt single-walled multiporous hair sensilla def: "These sensilla give mixed responses to fatty acids and volatile oils. Individual neurones within particular classes of sensilla appeared to have shown different sensitivity spectra to the range of carboxylic acids tested. Also the pattern of information provided by these cells could be intergrated to allow refined discrimination of fatty acid odours." [ISBN:0-85199-313-3] is_a: IDOMAL:0002210 ! response of single-walled multiporous hair sensilla [Term] id: IDOMAL:0002215 name: response of single-walled multiporous peg sensilla def: "The pegs, which arise from shallow depressions in the integument, are usually club-shaped but sometimes finger shaped. They are sensitive to olfactory stimuli." [ISBN:0-85199-313-3] synonym: "responses of capitate pegs" RELATED [ISBN:0-85199-313-3] synonym: "responses of sensilla basonica" RELATED [ISBN:0-85199-313-3] is_a: IDOMAL:0002136 ! response of olfactory sensilla [Term] id: IDOMAL:0002216 name: response to carbon dioxide def: "Electrophysiological studies with extracellular electrodes (on female Aedes aegypti) showed that the neurone producing the largest action potentials was the only one sensitive to carbon dioxide. CO2-sensitive neurones were silent in air without CO2, and had response thresholds between 150 and 300 ppm." [ISBN:0-85199-313-3] comment: Similar responses were obtained with male Aedes aegypti and with females of Aedes taeniorhynchys, Culex quinquefasciatus, Culiseta melanura and Anopheles stephensi. is_a: IDOMAL:0002215 ! response of single-walled multiporous peg sensilla [Term] id: IDOMAL:0002217 name: response to octenol def: "The neuron with the smallest spike height is sensitive to octenol. This neurone produces bursts of action potentials upon exposure of a sensillum to 2 s pulses of CO2-free air that had passed through a stimulus cartidge containing solutions of 1-octen-3-ol in mineral oil. The sensitivity of the mosquito neurones to 1-octen-3-ol was said to be equivalent to that of lepidopteran sensory neurones to pheromones when tested by similar protocols for stimulus preparation and delivery." [ISBN:0-85199-313-3] is_a: IDOMAL:0002215 ! response of single-walled multiporous peg sensilla [Term] id: IDOMAL:0002218 name: response of double-walled multiporous peg sensilla def: "The grooved peg sensilla of Aedes aegypti contain from two to five neurones, usually three. Spike analysis of extracellular recordings from grooved peg sensilla of Aedes epactius revealed spontaneous action potentials of three distinct amplitudes." [ISBN:0-412-40180-0] synonym: "responses of A3 sensilla" RELATED [ISBN:0-85199-313-3] synonym: "responses of grooved legs" RELATED [ISBN:0-85199-313-3] synonym: "responses of sensilla basiconica" RELATED [ISBN:0-85199-313-3] is_a: IDOMAL:0002136 ! response of olfactory sensilla [Term] id: IDOMAL:0002219 name: response to carboxylic acid def: "When exposed to lactic acid vapour, the grooved peg sensilla of Aedes aegypti exhibited one of three firing patterns: (i) a phasic-tonic increase in spike frequency; (ii) a tonic decrease in the frequency of spontaneous spikes; or (iii) no change in spike frequency. Thus neurones are excited or inhibited or are non-responsive." [ISBN:0-85199-313-3] is_a: IDOMAL:0002218 ! response of double-walled multiporous peg sensilla [Term] id: IDOMAL:0002220 name: response to water vapour def: "Electrophysiological evidence from different insects suggests that hygrosensory neurons occur in poreless sensilla. It is thought that absorption of water vapour by the cuticular wall results in deformation of the sensillum." [ISBN:0-85199-313-3] comment: The neurones that were examined (Kellog 1970) are not hygrosensory but were moisture-dependent, losing sensitivity at lower humidities. Kellog also was not working with double-walled multiporous sensilla. is_a: IDOMAL:0002218 ! response of double-walled multiporous peg sensilla [Term] id: IDOMAL:0002221 name: reception of physical stimuli def: "The reception of the physical stimuli is typically a three-stage process of coupling, transduction and encoding. Is made by the mosquito antennae, which are sensitive to a band of vibrational frequencies, pressure changes or displacements of air particles." [ISBN:0-85199-313-3] is_a: IDOMAL:0002130 ! sensory perception [Term] id: IDOMAL:0002222 name: transduction of receptor potential def: "Mechanical deformation of the dendritic membrane, producing receptor potentials." [ISBN:0-85199-313-3 "The biology of mosquitoes A.N.Clements pp.78"] comment: Most electrophysiological studies of sound reception have been undertaken with sharpened metal electrodes inserted into Johnston's organ.\nThe receptors potentials that are elicited in Johnston's organ by vibration of the antennal flagellum, when recorded via an extracellular electrode, are sinusoidal in form but occur at twice the frequency of the acoustic stimulus. This phenomenon has been termed frequency doubling. is_a: IDOMAL:0002125 ! nervous system process relationship: part_of IDOMAL:0002221 ! reception of physical stimuli relationship: preceded_by IDOMAL:0002063 ! sensory coupling [Term] id: IDOMAL:0002223 name: fiat process part def: "A processual entity [span:ProcessualEntity] that is part of a process but that does not have bona fide beginnings and endings corresponding to real discontinuities." [SPAN:fiat_process_part "http://www.ifomis.org/bfo/1.1/span#FiatProcessPart"] created_by: Pantelis creation_date: 2009-07-12T11:11:29Z [Term] id: IDOMAL:0002224 name: encoding of receptor potential def: "Is the conversion of receptor potentials to action potentials, which are beleived to arise in the cell membrane of the sensory neurone close to the junction between the cell body and axon." [ISBN:0-85199-313-3] is_a: IDOMAL:0002125 ! nervous system process relationship: part_of IDOMAL:0002221 ! reception of physical stimuli relationship: preceded_by IDOMAL:0002222 ! transduction of receptor potential [Term] id: IDOMAL:0002225 name: responses of the visual pigments and the chromophores def: "Conjugated proteins which are integral constituents of the membranes of photoreceptor organelles. Each consists of a chromophore and a apoprotein to which it is covalently linked. A number of different visual pigments are known from insect eyes." [ISBN:0-85199-313-3] is_a: IDOMAL:0001013 ! quality of vector relationship: part_of IDOMAL:0002185 ! larval vision [Term] id: IDOMAL:0002226 name: 11-cis configuration def: "When the chromophore is in the 11-cis configuration, the principal absorption peak of different visual pigments may appear anywhere in the spectrum between ultraviolet and yellow." [ISBN:0-85199-313-3] is_a: IDOMAL:0002225 ! responses of the visual pigments and the chromophores [Term] id: IDOMAL:0002227 name: all-trans configuration def: "When the chromophore is in the all-trans configuration, and the visual pigment is in the meta-state,the absorption peak appears within a much narrower range, usually in the blue but in higher Diptera in the orange." [ISBN:0-85199-313-3] is_a: IDOMAL:0002225 ! responses of the visual pigments and the chromophores [Term] id: IDOMAL:0002228 name: larval spectral sensitivity def: "The spectral sensitivity of a photoreceptor is determined by the absorption characteristics of its visual pigments. The eyes of different insects contain from one to four receptor types with distinct spectral sensitivities. Mosquito larvae exhibit a negative phototactic or diving response when first exposed to light at night or to a bright source by day, but this is soon followed by a return to the surface." [ISBN:0-85199-313-3] is_a: IDOMAL:0002225 ! responses of the visual pigments and the chromophores [Term] id: IDOMAL:0002229 name: apposition eye def: "A compound eye with no separation between the crystalline-cone layer and the retinula, each rhabdom receiving light only from its own corneal lens." [ISBN:0-85199-313-3] is_a: IDOMAL:0002421 ! compound eye [Term] id: IDOMAL:0002230 name: superposition eye def: "A compound eye in which a clear space is interposed between the dioptric apparatus and the retinula, and light from several corneal lenses falls on each rhabdom, producing a much brighter image." [ISBN:0-85199-313-3] is_a: IDOMAL:0002421 ! compound eye [Term] id: IDOMAL:0002231 name: neural superposition eye def: "A compound eye in certain diptera in which the rhabdomeres act as independent light guides." [ISBN:0-85199-313-3] is_a: IDOMAL:0002421 ! compound eye [Term] id: IDOMAL:0002232 name: quality of optical resolution def: "For an eye to be capable of resolving fine detail, the angular separation between the receptors must be small. Therefore, in compound eyes the smaller the angle between the optical axes of two adjacent ommatidia, the greater the potential of the eye to resolve detail. The interommatidial angle can be measured in a number of ways." [ISBN:0-85199-313-3] is_a: IDOMAL:0001013 ! quality of vector relationship: realized_by IDOMAL:0002184 ! adult vision [Term] id: IDOMAL:0002233 name: quality of optical sensitivity def: "The sensitivity (S) of an eye is a measure of the size of the photon sample that it can capture from each direction." [ISBN:0-85199-313-3] is_a: IDOMAL:0001013 ! quality of vector relationship: realized_by IDOMAL:0002184 ! adult vision [Term] id: IDOMAL:0002234 name: minimum resolvable angle of an eye def: "For an eye for a grating (not for a point) is twice the interommatidial angle." [ISBN:0-85199-313-3] is_a: IDOMAL:0002232 ! quality of optical resolution [Term] id: IDOMAL:0002235 name: acuity def: "Is the highest spatial frequency that an eye can resolve." [ISBN:0-85199-313-3] comment: The acuity of an eye is governed by its spatial frequency only if the quality of its optics is not limited by other structural or environmental factors. is_a: IDOMAL:0002232 ! quality of optical resolution [Term] id: IDOMAL:0002236 name: angular sensitivity def: "The angular sensitivity of an ommatidium is determined by three parameters: (i) optical blurring by the lens; (ii) the width of the rhabdom tip; nad (iii) the waveguide properties of the rhabdom." [ISBN:0-85199-313-3] is_a: IDOMAL:0002233 ! quality of optical sensitivity [Term] id: IDOMAL:0002237 name: ommatidial acceptance angle def: "The half-width of the Airy disc and the half-width of the rhabdom acceptance function combine to give the half-width of the ommatidial acceptance angle." [ISBN:0-85199-313-3] is_a: IDOMAL:0002233 ! quality of optical sensitivity [Term] id: IDOMAL:0002238 name: rhabdom acceptance angle def: "The rhabdoms of most insects are cylindrical in form and act as light guides, i.e. they trap and retain light by total internal reflection. The cone of light that such a cylinder can trap is narrow. The acceptance angle of the cylinder is limited by the critical angle for total internal reflection, and therefore is governed by the differenece of refractive index between the receptor itself and the surrounding cytoplasm." [ISBN:0-85199-313-3] is_a: IDOMAL:0002233 ! quality of optical sensitivity [Term] id: IDOMAL:0002239 name: orthokinesis def: "Is a change in linear speed or in frequency of locomotion." [ISBN:0-85199-313-3] is_a: IDOMAL:0002181 ! larval kinesis [Term] id: IDOMAL:0002240 name: klinokinesis def: "Is a change in the rate or frequency of turning." [ISBN:0-85199-313-3] is_a: IDOMAL:0002181 ! larval kinesis [Term] id: IDOMAL:0002241 name: protective behaviour def: "In some bodies of water, but not all, the water surface is a hazardous place due to predators. Larvae gain protection by a variety of means, including the occupation of transient biotopes, which often lack predators, or avoidance responses given to surface vibration or visual stimuli." [ISBN:0-85199-313-3] is_a: IDOMAL:0002109 ! response to thermal stimulus is_a: IDOMAL:0002134 ! response to chemical stimulus is_a: IDOMAL:0002139 ! larval behavioural process is_a: IDOMAL:0002140 ! pupal behavioural process is_a: IDOMAL:0002315 ! response to visual stimuli relationship: part_of IDOMAL:0002179 ! living at the water surface [Term] id: IDOMAL:0002242 name: kinetic response to chemical stimulus def: "They are an important part of feeding behaviour, causing larvae to remain in the location of food sources." [ISBN:0-85199-313-3] is_a: IDOMAL:0002134 ! response to chemical stimulus relationship: part_of IDOMAL:0002180 ! taxis [Term] id: IDOMAL:0002243 name: direct klinokinesis def: "When the turning increases with stimulus strength." [ISBN:0-85199-313-3] is_a: IDOMAL:0002240 ! klinokinesis [Term] id: IDOMAL:0002244 name: inverse klinokinesis def: "When the turning decreases with stimulus strength." [ISBN:0-85199-313-3] is_a: IDOMAL:0002240 ! klinokinesis [Term] id: IDOMAL:0002245 name: direct orthokinesis def: "When the movement increases with stimulus strength." [ISBN:0-85199-313-3] is_a: IDOMAL:0002239 ! orthokinesis [Term] id: IDOMAL:0002246 name: inverse orthokinesis def: "When the movement decreases with stimulus strength." [ISBN:0-85199-313-3] is_a: IDOMAL:0002239 ! orthokinesis [Term] id: IDOMAL:0002247 name: anautogeny def: "Refers to egg production that is dependent on protein intake." [ISBN:0-13-473276-3] is_a: IDOMAL:0001013 ! quality of vector relationship: part_of IDOMAL:0002091 ! process of oogenesis [Term] id: IDOMAL:0002248 name: autogeny def: "Egg production in the absence of all adult feeding." [ISBN:0-412-40180-0] comment: Autogeny is genetically determined, nevertheless environmental and other non-genetic factors play an important role on its expression. The females that are genetically autogenous do not invariably initiate vitellogenic ovarian development in the absence of blood feeding. is_a: IDOMAL:0001013 ! quality of vector relationship: part_of IDOMAL:0002091 ! process of oogenesis [Term] id: IDOMAL:0002249 name: facultative autogeny def: "Observed in genetically autogenous females that will engorge readily during the first ovarian cycle if they meet a host, but which can mature one batch of eggs without a blood meal." [ISBN:0-412-40180-0] is_a: IDOMAL:0002248 ! autogeny [Term] id: IDOMAL:0002250 name: obligatory autogeny def: "Observed in females that do not engorge during the first ovarian cycle, even when hosts are available." [ISBN:0-412-40180-0] is_a: IDOMAL:0002248 ! autogeny [Term] id: IDOMAL:0002251 name: monandry def: "The condition in which a female is inseminated by only a single male." [ISBN:0-85199-313-3] is_a: IDOMAL:0002073 ! insemination [Term] id: IDOMAL:0002252 name: protandry def: "The emergence of males before females into a seasonal breeding population." [ISBN:0-85199-313-3] comment: Species for which protandry has been recorded in wild populations include Aedes communis, Aedes impiger, Aedes nigripes, Aedes sierrensis and Aedes vittatus.\nIs widespread among insects and a number of reasons have been suggested for its evolution, for example, the prevention of inbreeding, the enhancement of reproductive success in males that emerge early, and natural selection for sexual size dimorphism. is_a: IDOMAL:0001013 ! quality of vector [Term] id: IDOMAL:0002253 name: polyandry def: "The condition in which a female is inseminated by more than one male." [ISBN:0-85199-313-3] synonym: "multiple insemination" RELATED [ISBN:0-85199-313-3] is_a: IDOMAL:0002073 ! insemination [Term] id: IDOMAL:0002254 name: senses and flight response during mating def: "Flight reactions and patterns expressed during mating." [ISBN:0-85199-313-3] is_a: IDOMAL:0002002 ! fiat process part of malaria vector relationship: part_of IDOMAL:0002000 ! mating [Term] id: IDOMAL:0002255 name: flight response during mating def: "The males of species that mate in flight fly towards a conspecific female when stimulated by her flight tone." [ISBN:0-85199-313-3] comment: Mating is initiated with the male and female still in flight. It may end with the pair still in flight or settled on vegetation or on the ground, but usually copulation is completed within seconds. is_a: IDOMAL:0002254 ! senses and flight response during mating [Term] id: IDOMAL:0002256 name: hearing response during mating def: "The signal to which male mosquitoes respond is the female's flight tone, and this a flying female can never switch off." [ISBN:0-85199-313-3] comment: Considering as a means of sound production, the wing beat has a very low efficiency, and the distance over which the flight sounds of female mosquitoes can be detected by conspecific males probably is not greater than about 30cm. is_a: GO:0050896 ! response to stimulus is_a: IDOMAL:0002254 ! senses and flight response during mating [Term] id: IDOMAL:0002257 name: response of olfactory sensillum during mating def: "The females of some insects emit long-range signals when sexual receptive, and switch off these signals when unreceptive." [ISBN:0-85199-313-3] is_a: IDOMAL:0002136 ! response of olfactory sensilla is_a: IDOMAL:0002254 ! senses and flight response during mating [Term] id: IDOMAL:0002258 name: response to visual stimulus during mating def: "Behavioural reactions and patterns caused by visual stimuli during mating." [ISBN:0-85199-313-3] is_a: IDOMAL:0002254 ! senses and flight response during mating [Term] id: IDOMAL:0002259 name: developmental changes after blood feeding def: "Within 24h of a first blood meal, the epithilial cells of the calyx become flattened and extended and start to develop microvilli, the calyx lumen becomes greatly enlarged, and the calyx assumes the shape of a distened sac. The muscle cells of the calyx undergo rather little development. During this period changes start in the lateral oviducts also, reaching completion by 72h post-blood meal. A distinct lumen forms within each lateral oviduct, the epithelium becomes folded, providing for distension of the lateral oviduct at ovulation, and the luminal surface of the epithelial cells becomes microvillate. The muscles cells grow substantially in volume, and their myofibrils and mitochondria increase in number and degree of organization." [ISBN:0-85199-313-3] comment: The process described concernes Aedes aegypti. In Anopheles, the columnar epithelium of the ampullae is thrown into folds during the first ovarian cycle. During this and each succeeding ovarian cycle the size of the ampullae increases due to accumulation of secretion within the columnar cells. is_a: IDOMAL:0002163 ! developmental process relationship: part_of IDOMAL:0002091 ! process of oogenesis [Term] id: IDOMAL:0002260 name: swarm quality def: "Most reports of swarming mosquitoes concern species of Anopheles, Culex and Aedes. Swarming has been described also in species of Psorophora, Culiseta, Uranotaenia, Armigeres and Coquilletidia.\nAll mosquito swarms have 3 characteristics in common:\n1) The individual members of a swarm fly in looping or zig-zag patterns characteristic of the species, and all keep within a limited space that is located in relation to some feature of the environment.\n2) The swarms consist predominately of males. When conspecific females enter a swarm, males approach and attempt to couple with them.\n3) Swarming is limited to times of day characteristic of the species, usually close to dusk and dawn." [ISBN:0-85199-313-3] is_a: IDOMAL:0001013 ! quality of vector relationship: realizes IDOMAL:0002074 ! assembly in station-keeping swarm [Term] id: IDOMAL:0002261 name: ceiling swarm def: "It occurs at a considerable height above the ground and extend over a large area like a ceiling. It develops only when there are extremely large numbers of males participanting." [ISBN:0-85199-313-3] comment: Ceiling swarms are not station-keeping swarms, although they make give rise to them. is_a: IDOMAL:0002260 ! swarm quality [Term] id: IDOMAL:0002262 name: free swarm def: "Occurs in areas of open ground and form over swarm markers. Free swarms reappear, day after day, over position that have no characteristics discernible to human eyes." [ISBN:0-85199-313-3] comment: Swarms of Anopheles gambie and An aeabiensis formed over parts of flat, open ground within an area of scattered huts and trees. is_a: IDOMAL:0002260 ! swarm quality [Term] id: IDOMAL:0002263 name: marker swarm def: "Occurs in areas of open ground and forms over small areas of visual contrast, for example over patches of paler or darker earth, piles of dunk, bushes, small pools etc." [ISBN:0-85199-313-3] comment: Changes in reflectance can lead to swarm markers being deserted. Some permanent swarm markers may be used by a species year after year. is_a: IDOMAL:0002260 ! swarm quality [Term] id: IDOMAL:0002264 name: space swarm def: "Forms within breaks in vegetation or at vegetational boundaries, and may be within a range of elevations. The flight paths are delineated by vegetational boundaries or by shafts of sunlight within the breaks." [ISBN:0-85199-313-3] is_a: IDOMAL:0002260 ! swarm quality [Term] id: IDOMAL:0002265 name: top swarm def: "Forms over prominent vertical ojects, such a tree tops, chimneys or church steeples." [ISBN:0-85199-313-3] is_a: IDOMAL:0002260 ! swarm quality [Term] id: IDOMAL:0002266 name: response to sex pheromone def: "A pheromone is any chemical or set of chemicals produced by a living organism that transmits a message to other members of the same species. Sex pheromones indicate the availability of the female for breeding." [http://www.wikipedia.org] comment: The involvement of sex pheromones in species recognition by mosquitoes has been postulated by a number of authors but usually has not been confirmed by experimental investigation.\nThere is evidence for the presence of a contact peromone on the legs of females of the Culiseta inormata. Contact with isolated female legs was sufficient to release coupling behaviour in males. The active substance was non-volatile, heat-stable, and soluble in solvents of intermediate polarity. is_a: IDOMAL:0002134 ! response to chemical stimulus relationship: part_of IDOMAL:0002000 ! mating [Term] id: IDOMAL:0002267 name: sexual responsiveness and refractoriness def: "The male and female behavioural patterns for sexual stimuli after the completion of their sexual maturation." [ISBN:0-85199-313-3] is_a: IDOMAL:0001013 ! quality of vector relationship: part_of IDOMAL:0002000 ! mating [Term] id: IDOMAL:0002268 name: male fecundity def: "The ability of a male to inseminate a number of females depends upon the supply of both spermatozoa and accessory gland secretion. The average male could fully inseminate four to five females and transmit small amounts of sperm to an additional two to four females." [ISBN:0-85199-313-3] comment: Reports of insemination that do not quantify sperm transfer are of only limited value. relationship: part_of IDOMAL:0002267 ! sexual responsiveness and refractoriness [Term] id: IDOMAL:0002269 name: sexual refractoriness def: "Once a female mosquito has undergone a consummated union she usually becomes refractory to further mating, at least until after completing a gonotropic cycle. Female sexual refractoriness has immediate and delayed components." [ISBN:0-85199-313-3] relationship: part_of IDOMAL:0002267 ! sexual responsiveness and refractoriness [Term] id: IDOMAL:0002270 name: swarming def: "A strongly cyclic adult behaviour, and most species swarm for short periods around sunset and sunrise.\nIf swarm is considered as a form of epigamic behaviour, it must provide a selective advantage pertaining to reproduction. The pattern of flight is specific." [ISBN:0-85199-313-3] is_a: IDOMAL:0002141 ! adult behavioural process relationship: part_of IDOMAL:0002000 ! mating [Term] id: IDOMAL:0002271 name: flight patterns in swarms def: "The lower level of station-keeping swarms reflects the pattern of the individual members. A swarming mosquito flies in a particula pattern an often, for a number of seconds or longer, remains within a small space as thought it were confined in a box." [ISBN:0-85199-313-3] comment: Swarms usually consist of a number of individuals, but single mosquitoes may exhibit swarming behaviour. The presence of other mosquitoes can only modify this behaviour.\nLight wind can influence the orientation of swarming mosquitoes. relationship: part_of IDOMAL:0002270 ! swarming [Term] id: IDOMAL:0002272 name: mating in resting sites def: "A characteristic of sabethines is that the males patrol the area of vegetation in which conspecific females rest. Of species that assembly in station-keeping swarms, the males and females may rest in the same places, and contact between males and females after arousal can lead to mating." [ISBN:0-85199-313-3] comment: The vegetation in which conspecific females rest are often the vertical and horizontal surfaces of tree trunks, stems or branches. relationship: part_of IDOMAL:0002270 ! swarming [Term] id: IDOMAL:0002273 name: oostasis def: "The mechanisms that prevent development of another series of follicles in gravid females." [ISBN:0-412-40180-0] is_a: IDOMAL:0001059 ! process of malaria vector relationship: part_of IDOMAL:0002091 ! process of oogenesis [Term] id: IDOMAL:0002274 name: ovarian cycle def: "In mosquitoes, egg production is a cyclic process. Batches of sister follicles is separate successively from the germania of the many ovarioles, and the follicles of each batch develop synchronously through a sequence of steps until the oocytes they contain are fully formed. The steps from the formation of a batch of mature oocytes constitute an ovarian cycle." [ISBN:0-412-40180-0] comment: The most important developmental events during an ovarian cycle are: (i) differentiation of the oocytes. (ii) reductional division of the oocytes' chromosomes. (iii) Synthesis of RNA by oocytes and nurse cells and its deposition in the ooplasm. (iv)Synthesis of yolk by the fat body and its deposition in the ooplasm. (v)Formation of the chorion. is_a: IDOMAL:0002002 ! fiat process part of malaria vector relationship: part_of IDOMAL:0002091 ! process of oogenesis [Term] id: IDOMAL:0002275 name: developmental gates def: "The gates are points of potential or actual arrest at which follicular development will be halted, without detriment to the follicles, unless or until specific physiological conditions occur. These might entail exposure to specific stimuli or, conceptually at least, the absence of specific inhibitors." [ISBN:0-412-40180-0] is_a: IDOMAL:0002001 ! spatiotemporal region relationship: part_of IDOMAL:0002274 ! ovarian cycle [Term] id: IDOMAL:0002276 name: ovarian developmental stages according Christophers def: "This description of ovarian stages is based on the development of primary ovarian follicles in Ae aegypti and Cx pipiens. Anopheles gambie shows the following differences: there is no distinct stage Ib characterized by differnces between oocyte and nurse cells, and by stage IIa the oocyte half fills the follicle." [ISBN:0-412-40180-0] is_a: IDOMAL:0002002 ! fiat process part of malaria vector relationship: part_of IDOMAL:0002274 ! ovarian cycle [Term] id: IDOMAL:0002277 name: ovarian developmental stages according Troy et al. def: "The ovarian cycle can be divided into sequential phases and stages using physiological and anatomical criteria." [ISBN:0-412-40180-0] is_a: IDOMAL:0002002 ! fiat process part of malaria vector relationship: part_of IDOMAL:0002274 ! ovarian cycle [Term] id: IDOMAL:0002278 name: germarial gate def: "In the earliest stage at which ovarian follicles are visibly distinct they are still closely attached to the germaria (Christopher's stage G). Normally the primary follicles separate from the germaria shortly after emergence, and each subsequent batch of follicles leaves the germarial reting stage when a blood meal restarts the ovarian cycle." [ISBN:0-412-40180-0] is_a: IDOMAL:0002275 ! developmental gates relationship: part_of IDOMAL:0002297 ! regulation of follicle growth and competenece [Term] id: IDOMAL:0002279 name: maturation gate def: "Oocytes that have reached stage V and are ready for ovulation are often described as mature, yet their chromosomes are still in the metaphase of the first meiotic division. Meiosis is resumed only after the oocytes have been penetrated by sperm at oviposition. Thus the oocytes are held in a state of nuclear stasis from the time they are ready for ovulation until syngamy stimulates completion of the maturation divisions. The maturation resting stage normally lasts only a few hours, until the appropriate activity rhythm leads to ovulation and oviposition. However, if females are unable to oviposit, the stage V oocytes can remain viable within ovaries for 15days or even more." [ISBN:0-412-40180-0] is_a: IDOMAL:0002275 ! developmental gates [Term] id: IDOMAL:0002280 name: previtellogenic gate def: "The primary follicles may develop directly to Christopher's stage IIa or IIb after emergence, or may develop to this stage only after the females have fed. The primary follicles of anautogenous females then enter the previtellogenic resting stage, remaining in it until the female has taken a blood meal. The primary follicles of autogenous females pass the previtellogenic gate without arrest, demonstrating the conditional nature of the gates." [ISBN:0-412-40180-0] is_a: IDOMAL:0002275 ! developmental gates [Term] id: IDOMAL:0002281 name: stage I gate def: "After follicles have separated from the germaria they grow slightly but may soon enter a state of arrest. Follicles in the stage I resting are about 40-50 micrometers long, their epithelia consist of relatively few cells, and their oocytes are visibly distinct but do not contain lipid or others droplets in the ooplasm." [ISBN:0-412-40180-0] is_a: IDOMAL:0002275 ! developmental gates relationship: part_of IDOMAL:0002297 ! regulation of follicle growth and competenece [Term] id: IDOMAL:0002282 name: stage III gate def: "In most anautogenous species, follicles that pass the previtellogenic gate and start to deposit yolk in the oocytes either develop to maturity or are resorbed. There have been a few reports of follicles entering arrest during the course of vitellogenesis, and they indicate the existence of a stage III gate." [ISBN:0-412-40180-0] is_a: IDOMAL:0002275 ! developmental gates [Term] id: IDOMAL:0002283 name: stage G def: "The follicle has partly separated from the germarium but the oocyte is not entirely surrounded by epithelium." [ISBN:0-412-40180-0] is_a: IDOMAL:0002276 ! ovarian developmental stages according Christophers [Term] id: IDOMAL:0002284 name: response to oviposition-arrestant def: "Arrestants are substances that induces gravid females to remain in their presence through their own undirected kinetic responses, either by stopping their locomotion or changing their rate of turning." [ISBN:0-85199-313-3] is_a: IDOMAL:0002309 ! response to chemical cue during pre-oviposition stage and oviposition [Term] id: IDOMAL:0002285 name: stage Ia def: "The follicle has separated from the germarium and the oocyte is entirely surrounded by follicular epithelium. The oocyte is not visibly distinct from the nurse cells." [ISBN:0-412-40180-0] is_a: IDOMAL:0002276 ! ovarian developmental stages according Christophers [Term] id: IDOMAL:0002286 name: stage Ib def: "The oocyte is distinguishable from the nurse cells by its smaller nucleus and prominent nucleolus." [ISBN:0-412-40180-0] is_a: IDOMAL:0002276 ! ovarian developmental stages according Christophers [Term] id: IDOMAL:0002287 name: stage IIa def: "Some very small refractile lipid droplets are visible in the ooplasm." [ISBN:0-412-40180-0] is_a: IDOMAL:0002276 ! ovarian developmental stages according Christophers [Term] id: IDOMAL:0002288 name: stage IIb def: "The ooplasm contains fine lipid droplets, these cause the oocyte to appear slightly dark under transmitted light but white by reflected light. No large droplets are visible in the ooplasm, and no ooplasmic inclusions strain with neutral red." [ISBN:0-412-40180-0] is_a: IDOMAL:0002276 ! ovarian developmental stages according Christophers [Term] id: IDOMAL:0002289 name: stage IIIa def: "The ooplasm is clouded with inclusions distinctly. At first the inclusions are small. Subsequently, large yolks spheres appear which stain yellowish-brown with neutral red. These yolk spheres are of smilar diameter to the epithelial cell nucleoli, and are about 0,2 to 0,3 times the diameter of the oocytes' nucleolus. The oocyte's nucleus progressively occupies up to 50% of the length of the follicle." [ISBN:0-412-40180-0] is_a: IDOMAL:0002276 ! ovarian developmental stages according Christophers [Term] id: IDOMAL:0002290 name: stage IIIb def: "The follicle has increased in size considerably but without changing shape. The oocyte occupies >50% to 70% of the length of the follicle." [ISBN:0-412-40180-0] is_a: IDOMAL:0002276 ! ovarian developmental stages according Christophers [Term] id: IDOMAL:0002291 name: stage IVa def: "The follicle has grown further and has become slightly narrower, starting to assume the shape of a mature oocyte. The oocyte occupies 90% of the follicle length. The nurse cells still appear intact and occupy about 10% of the follicle length." [ISBN:0-412-40180-0] is_a: IDOMAL:0002276 ! ovarian developmental stages according Christophers [Term] id: IDOMAL:0002292 name: stage IVb def: "The follicle assumes the shape of the mature oocyte, or almost so, but has not reached full length. The nurse cells have degenerated and at first stain bright crimson with neutral red; later in this stage they disappear. Chorionic structures start to appear." [ISBN:0-412-40180-0] is_a: IDOMAL:0002276 ! ovarian developmental stages according Christophers [Term] id: IDOMAL:0002293 name: stage V def: "The oocyte structures its full length. The follicular epithelium degenerates. Chorionic structures such as the floats (Anopheles), micropyle cup (Culex) or surface sculpturing (Aedes) become fully formed." [ISBN:0-412-40180-0] is_a: IDOMAL:0002276 ! ovarian developmental stages according Christophers [Term] id: IDOMAL:0002294 name: response to oviposition-attractant def: "Attractants are substances that induces gravid females to make oriented movements towards its source." [ISBN:0-85199-313-3] is_a: IDOMAL:0002309 ! response to chemical cue during pre-oviposition stage and oviposition [Term] id: IDOMAL:0002295 name: presence of juvenile hormone def: "The juvenile hormone in females of Aedes aegypti increases markedly between 24 and 72h after emergence. Circumstancial evidence associating JH with onset of responsiveness to host cues was obtained with diapausing mosquitoes. Application of large doses of the JH analogue methoprene to diapausing females of Anopheles freeborni and Culex tarsalis hastened their diapause development, including responsiveness to vertebrate hosts." [ISBN:0-85199-313-3] synonym: "presence of JH" RELATED [ISBN:0-85199-313-3] relationship: part_of IDOMAL:0002094 ! previtellogenic phase relationship: part_of IDOMAL:0002342 ! development of competence to respond to host cue [Term] id: IDOMAL:0002296 name: secretion of juvenile hormone def: "Juvenile hormones is released after eclosion and stimulates the devlopment of host-seeking behaviour. Little is known about the regulation of juvenile hormone secretion in mosquitoes. Decapitation immediately after emergence has the same effect on follicle development as allatectomy, which suggests that the brain is involved." [ISBN:0-12-473276-3, ISBN:0-412-40180-0] comment: The mechanism of release of JH after eclosion does not appear to operate in Aedes aegypti. There is evidence from Aedes aegypti of the ovaries affecting JH secretion. is_a: IDOMAL:0002295 ! presence of juvenile hormone [Term] id: IDOMAL:0002297 name: regulation of follicle growth and competenece def: "Two developmental gates control the course of previtellogenic development." [ISBN:0-412-40180-0] is_a: IDOMAL:0002442 ! regulation of biological process relationship: part_of IDOMAL:0002094 ! previtellogenic phase [Term] id: IDOMAL:0002298 name: response to oviposition-deterrent def: "When present, the deterrents (non-volatile substances) inhibit oviposition ." [ISBN:0-85199-313-3] is_a: IDOMAL:0002309 ! response to chemical cue during pre-oviposition stage and oviposition [Term] id: IDOMAL:0002299 name: response to predator def: "The weight of evidence suggests that gravid females respond negatively to chemical substances emanating from certain predators, but proof of this requires that these substances be isolated, identified and tested as repellents or deterents." [ISBN:0-85199-313-3] is_a: IDOMAL:0002298 ! response to oviposition-deterrent is_a: IDOMAL:0002300 ! response to oviposition-repellent [Term] id: IDOMAL:0002300 name: response to oviposition-repellent def: "Gravid females make oriented movements away from its source of any oviposition repellent." [ISBN:0-85199-313-3] is_a: IDOMAL:0002309 ! response to chemical cue during pre-oviposition stage and oviposition [Term] id: IDOMAL:0002301 name: response to sugar solution def: "Electophysiological analysis of the reflex response showed that the labellar muscles are activated some 40ms after stimulation of the aboral sensilla with sucrose." [ISBN:0-412-40180-0] is_a: IDOMAL:0002135 ! response of gustatory sensilla [Term] id: IDOMAL:0002302 name: adult response of olfactory sensilla while feeding on plant sugar def: "There is some evidence of mosquitoes responding to plant odours in the field." [ISBN:0-85199-313-3] comment: The results were obtained after fine netting bags had been placed over inflorescences of Silene otites (Caryophyllaceae). The experiment was conducted with many variations to prove the responses. is_a: IDOMAL:0002136 ! response of olfactory sensilla relationship: part_of IDOMAL:0002400 ! feeding on plant sugar [Term] id: IDOMAL:0002303 name: adult response of olfactory sensilla while host-seeking def: "Female mosquitoes respond to host odour (CO2 emission, water vapour, volatiles molecules)." [ISBN:0-85199-313-3] is_a: IDOMAL:0002136 ! response of olfactory sensilla [Term] id: IDOMAL:0002304 name: response to host odour def: "Host odour is here taken to comprise all volatile compounds, organic and inorganic, that emanate from a vertebrate host and that stimulate mosquito chemosensilla." [ISBN:0-85199-313-3] is_a: IDOMAL:0002303 ! adult response of olfactory sensilla while host-seeking relationship: part_of IDOMAL:0002023 ! long-range approach [Term] id: IDOMAL:0002305 name: development of competence def: "Short, single walled, multiporous hair sensilla on the antennae of females Aedes, Culex and Anopheles give electrical responses to volatile compounds suspected of being oviposition-site attractants." [ISBN:0-85199-313-3] comment: The sensilla of gravid females showed greater sensitivity to one of these, methyl butyrate, than did those of non-blood-fed females. Non-blood-fed females of Aedes aegypti were unresponsive to methyl propionate vapour in an olfactometer, and females that had blood fed 24h earlier were equally unresponsive. 72-96h after blood feeding they became highly responsive. is_a: IDOMAL:0002002 ! fiat process part of malaria vector relationship: part_of IDOMAL:0002177 ! pre-oviposition behaviour [Term] id: IDOMAL:0002307 name: response to fatty acid def: "Fatty acids, i.e. saturated and unsaturated monobasic carboxylic acids, when active with gravid females, tended to induce negative responses. Saturated fatty acids from C2 to C11 yielded significant negative responses." [ISBN:0-85199-313-3] is_a: IDOMAL:0002300 ! response to oviposition-repellent [Term] id: IDOMAL:0002308 name: increased sensitivity of olfactory sensillum def: "Mosquitoes that belong to this category contain three types of neurones that variously are excited by lactic acid vapour, inhibited by it or unresponsive to it." [ISBN:0-85199-313-3] is_a: IDOMAL:0001013 ! quality of vector relationship: part_of IDOMAL:0002342 ! development of competence to respond to host cue [Term] id: IDOMAL:0002309 name: response to chemical cue during pre-oviposition stage and oviposition def: "Behavioural responses of the female to chemical stimuli during the stages of pre-oviposition and oviposition." [ISBN:0-85199-313-3] is_a: IDOMAL:0002136 ! response of olfactory sensilla relationship: part_of IDOMAL:0002177 ! pre-oviposition behaviour [Term] id: IDOMAL:0002310 name: adult female feeding behaviour def: "In nature mosquitoes feed on nectar or blood. Like some other blood-sucking Diptera, usually pass nectar and other plant juices to the crop and dorsal diverticula, but pass blood to the stomach. This separation of nectar and blood permits females to store nectar meal in the crop, passing slowly to the midgut for absorption, while leaving the stomach empty to receive a blood meal at any time." [ISBN:0-412-40180-0] is_a: IDOMAL:0002004 ! adult feeding behaviour [Term] id: IDOMAL:0002311 name: response to oviposition-stimulant def: "Stimulants are substances that elicit oviposition." [ISBN:0-85199-313-3] is_a: IDOMAL:0002309 ! response to chemical cue during pre-oviposition stage and oviposition [Term] id: IDOMAL:0002312 name: optomotor response def: "Is a reflex turning of the head or whole body of an animal in response to a movement of its surroundings." [ISBN:0-85199-313-3] comment: The response can be elicited experimentally with moving stripes. When a pattern of stripes passes across an insect's field of view, each rhabdom perceives the pattern as a modulation of light intensity. is_a: GO:0050896 ! response to stimulus [Term] id: IDOMAL:0002313 name: response to artificial object def: "The responses of mosquitoes to artificial objects have important implications for trap design, but their biological significance is uncertain." [ISBN:0-85199-313-3] is_a: IDOMAL:0002080 ! response of flying mosquito to visible object [Term] id: IDOMAL:0002314 name: response to shade def: "Shade can affect mosquito responses." [ISBN:0-85199-313-3] is_a: IDOMAL:0002080 ! response of flying mosquito to visible object [Term] id: IDOMAL:0002315 name: response to visual stimuli def: "Behavioural patterns expressed as a reaction to visual stimuli." [ISBN:0-85199-313-3] is_a: GO:0050896 ! response to stimulus [Term] id: IDOMAL:0002316 name: escape behaviour def: "Larvae and pupae that are at the water surface respond to certain stimuli with escape behaviour, often called an alarm response. Usually this takes the form of diving, and at a visibly more rapid rate than in descents made for feeding." [ISBN:0-85199-313-3] comment: Escape behaviour in response to visual stimuli has not been very extensively studied, and the results obtained with some experimental procedures must be reviewed cautiously. synonym: "alarm response" NARROW [ISBN:0-85199-313-3] is_a: IDOMAL:0002241 ! protective behaviour [Term] id: IDOMAL:0002317 name: adult responses to visual stimulus def: "It is reported that mosquitoes - whether diurnal, crepuscular or nocturnal in activity - fed most often from lighter flowers." [ISBN:0-85199-313-3] comment: White, pink and yellow flowers were attended by mosquitoes when closely adjacent darker flowers were not. Thus white clover (Trifolium repens) and white melilo. relationship: part_of IDOMAL:0002400 ! feeding on plant sugar [Term] id: IDOMAL:0002318 name: ingestion of sugar solution def: "When the tarsi of a walking mosquito touch a drop of sugar solution the mosquito stops moving or turns, and directs its proboscis towards the stimulus. The tip of the proboskis is placed in contact with the fluid, and when the chemosensory hairs on the aboral surface of the labella are stimulated the labellar lobes spread apart giving the so-called labellar response. Once the labellar lobes have parted, the oral surfaces of the ladella lie flat on the droplet and the external surfaces face away from it. The fluid immediately spreads over the hydrophilic oral surfaces of the labella and their chemosensilla, and over the ligul, submerging the tip of the labrum. When touched by fluid the ligula rapidly increases in size, probably due to a combination of physical forces on the cuticle and internal pressure of haemolymph." [ISBN:0-412-40180-0] is_a: IDOMAL:0002062 ! sugar feeding [Term] id: IDOMAL:0002319 name: egg laying def: "This term is used here in a broad sense, to include all the behavioural and physiological processes of a gravid female that lead up to and terminate in the deposition of eggs in an appropriate biotope. Egg-laying activity is cyclic, occurring in one or two peaks during the diel, and its timing is regulated by an endogenous, circadian rhythm." [ISBN:0-85199-313-3] is_a: IDOMAL:0002112 ! physiological process of malaria vector [Term] id: IDOMAL:0002320 name: oviposition def: "The act of depositing eggs." [ISBN:0-85199-313-3] is_a: IDOMAL:0002002 ! fiat process part of malaria vector is_a: IDOMAL:0002319 ! egg laying relationship: part_of IDOMAL:0002160 ! reproduction [Term] id: IDOMAL:0002321 name: synthesis of reserves def: "Mosquitoes conform with other insects in maintaining lipid and glycogen stores in the fat body. Glycogen is also stored in the flight muscles, and trehalose is stored in the haemolymph." [ISBN:0-412-40180-0] relationship: part_of IDOMAL:0002162 ! adult energy metabolism [Term] id: IDOMAL:0002322 name: Anopheles' oviposition behaviour def: "Anoplines exhibit a variety of oviposition behaviours. None oviposited though while settled on the water surface. A number of anopelines will deposit eggs on moist surfaces." [ISBN:0-85199-313-3] comment: Wild females of Anopheles melas have been observed ovipositing while perched on the vertica surface of pneumatophores in unflooded Avicennia mangover swamps. There has been one report of an anopheline drinking before oviposition (Anopheles messeae). Oviposition without drinking was reported for Anopheles maculipennis sensus stricto and Anopheles atroparvus. is_a: IDOMAL:0002427 ! egg laying behaviour [Term] id: IDOMAL:0002323 name: descent to the water surface def: "After a period of flying to and against the roof of the cage, the mosquitoes began to make descents to the floor. Often this was an ordinary diagonal flight movement, but sometimes this descent was a 'pancake landing'." [ISBN:0-85199-313-3] is_a: IDOMAL:0002002 ! fiat process part of malaria vector relationship: part_of IDOMAL:0002177 ! pre-oviposition behaviour [Term] id: IDOMAL:0002324 name: hovering def: "A female that had touched the water surface changed her mode of flight abruptly, beginning to hover, with little displacement in space. Sometimes she stayed in almost exactly the same spot or bobbed up and down 10mm or so vertically or obliqely, or she might swing through an arc of 20-100mm dipping at each end." [ISBN:0-85199-313-3] is_a: IDOMAL:0002002 ! fiat process part of malaria vector relationship: part_of IDOMAL:0002177 ! pre-oviposition behaviour [Term] id: IDOMAL:0002325 name: skin-hopping def: "Once arrived at the floor, the mosquitoes flew about at speeds 0,36m/s and at height that usually was 20-40mm. In the course of this horizontal flight they dipped again and again to touch the floor, at spaced intervals varying between 0,06-0,2m. The direction appeared to be random." [ISBN:0-85199-313-3] is_a: IDOMAL:0002002 ! fiat process part of malaria vector relationship: part_of IDOMAL:0002177 ! pre-oviposition behaviour [Term] id: IDOMAL:0002326 name: response to optical cue during pre-oviposition stage and oviposition def: "The optical cues to which gravid females respond at oviposition sites may come from the water body itself or from its immediate surroundings." [ISBN:0-85199-313-3] is_a: IDOMAL:0002315 ! response to visual stimuli relationship: part_of IDOMAL:0002177 ! pre-oviposition behaviour [Term] id: IDOMAL:0002327 name: response to other visual and physical parameters during pre-oviposition stage and oviposition def: "For species in which the feeding and resting habitat is different from the oviposition habitat, the gravid females must respond to cues that characterize the 'landscape' before responding to stimuli that characterize specific oviposition sites." [ISBN:0-85199-313-3] comment: Very little is known about the responses of mosquitoes to 'landscape', but it is likely that visual cues are particularly important. is_a: IDOMAL:0002315 ! response to visual stimuli relationship: part_of IDOMAL:0002177 ! pre-oviposition behaviour [Term] id: IDOMAL:0002328 name: response to chromaticity def: "Chromaticity results from (i)its hue, or dominant wavelengths, and (ii) its chroma (saturation), the extend to which the predominant colour is unadulterated with white. Experiments with females of Aedes aegypti showed that acceptance was low to green and yellow-green, moderate to orange, and high to violet and red." [ISBN:0-85199-313-3] is_a: IDOMAL:0002326 ! response to optical cue during pre-oviposition stage and oviposition [Term] id: IDOMAL:0002329 name: response to lightness of the water surface def: "Observing that when kept in complete darkness in a roomsized cage females of Culex quinquefasciatus laid in the oviposition dishes provided (dishes which had chemical cues), whereas females of Anopheles darlingi died without ovipositing. De Zalueta (1950) postulated that visual stimuli were essential for egg laying by Andarlingi but not for Culex quinquefasiatus, for which chemical stimuli were more important." [ISBN:0-85199-313-3] comment: Light contrast and dark contrast may both have different causes. The apparent lightness of a body of water may be due to reflection from a pale substratum or to specular reflection from the water surface. A body of water may appear dark relative to its surroundings due to high absorbance by the water or its substratum or to a shielding from incident light. is_a: IDOMAL:0002326 ! response to optical cue during pre-oviposition stage and oviposition [Term] id: IDOMAL:0002330 name: response to shade of water surface def: "The importance of shade for some species has been demonstrated by its removal. The effect of shade on gravid females is not necessarily direct; for example , it might affect the water temperature of a larval habitat or its chemical composition as a result of leaf fall." [ISBN:0-85199-313-3] comment: Differential responses by egg-laying females of a number of species were revealed by a study of larval densities in a tyre dump, where some tyres were exposed to direct sunlight and others were shaded throughout the entire. is_a: IDOMAL:0002326 ! response to optical cue during pre-oviposition stage and oviposition [Term] id: IDOMAL:0002331 name: response to physical obstruction def: "Dense vegetation is the main physical obstruction. The females of some species must pass through dense vegetation to approach their oviposition sites." [ISBN:0-85199-313-3] comment: The larval habitat of Uranotaenia anhydor at Saratoga Springs, California, was effetively subterranean. Egg rafts and larvae were foun only in pockets of water situated between clumps of the rush Scirpus. These were covered over so densely with mats formed from previous years' growth of rush that the water was in almost darkness. is_a: IDOMAL:0002327 ! response to other visual and physical parameters during pre-oviposition stage and oviposition [Term] id: IDOMAL:0002332 name: composition of reserves def: "The extent of the carbohydrate and lipid reserves and of the protein content of mosquitoes." [ISBN:0-412-40180-0] is_a: IDOMAL:0002321 ! synthesis of reserves [Term] id: IDOMAL:0002333 name: response to elevation def: "The oviposition sites of all ground-water mosquitoes are necessarily at ground-level, but for many species that develop in phytotelmata, the oviposition site is above ground level. This height varies from very moderate to very substantial, the most elevated larval habitats being those of some forest-inhabiting species that live in tree-holes or epiphytic bromeliads." [ISBN:0-85199-313-3] is_a: IDOMAL:0002327 ! response to other visual and physical parameters during pre-oviposition stage and oviposition [Term] id: IDOMAL:0002334 name: response to certain combination of factors def: "The responses of gravid females to particular oviposition-site characteristics might change when experienced simultaneously with other characteristics." [ISBN:0-85199-313-3] comment: Pairs of factors to which the responses were compared and contrasted when exposed singly and in combination were: (i)type of surface-open water or moistened filter paper. (ii)Surface texture-rough or smooth, moistened filter paper, affecting olfactory receptors. (iii)Smell-presence or absence of the odour of horse-dung suspension, affecting olfactory receptors. (iv)Salinity-distilled water or 0,086M NaCl, affecting contact chemoreceptors. (v)Lightness- of grey or black filter paper-affecting visual receptors. is_a: IDOMAL:0002327 ! response to other visual and physical parameters during pre-oviposition stage and oviposition [Term] id: IDOMAL:0002335 name: response to water movement def: "The species Anopheles minimus is known to lay eggs in small, shaded pools adjacent to running water. The females were little influenced by continuous surface ripples." [ISBN:0-85199-313-3] is_a: IDOMAL:0002327 ! response to other visual and physical parameters during pre-oviposition stage and oviposition [Term] id: IDOMAL:0002336 name: response to soil surface characteristic def: "For its acceptability to gravid females, three characteristics of soil are important, namely: the soil type, the moisture content and the soil texture." [ISBN:0-85199-313-3] comment: Species of Aedes and Psorophora characteristically deposit their eggs on substrata immediately adjacent to bodies of water or on moist substrata in places subject to inundation.\nThe importance of the characteristics of a soil surface for its acceptability to gravid females was illustrated by the use of a human-made habitat by 2 flood water mosquitoes, Aedes vexans and Psorophora columbiae.\nSurvival of the eggs on moist surfaces is an important aspect of anophelines fitness. is_a: IDOMAL:0002327 ! response to other visual and physical parameters during pre-oviposition stage and oviposition [Term] id: IDOMAL:0002337 name: reserves from blood protein def: "Conversion of the digestion products into glycogen and triacylglycerol deposits." [ISBN:0-412-40180-0] comment: A blood meal can replace nectar as an exogenous energy source. is_a: IDOMAL:0002321 ! synthesis of reserves [Term] id: IDOMAL:0002338 name: termination of responsiveness def: "The responsiveness of females of Aedes aegytpi to oviposition-site cues ceases after egg laying. Oviposition from the connected ovary was permitted in certain females, and responsiveness of all females to attractants was assessed. Oviposition from a sigle intact ovary was sufficient to terminate responsiveness to attractants, even when the abdomen contained a mature isolated ovary." [ISBN:0-85199-313-3] comment: Klowden concluded that nervous stimuli lead to the termination of responsiveness to oviposition-site stimuli. is_a: IDOMAL:0002437 ! process_boundary relationship: part_of IDOMAL:0002177 ! pre-oviposition behaviour [Term] id: IDOMAL:0002339 name: reserves from sugar feeding def: "Meals of sugar lead to the deposition of glycogen and lipid in the fat body and of glycogen in the flight muscles." [ISBN:0-412-40180-0] is_a: IDOMAL:0002321 ! synthesis of reserves [Term] id: IDOMAL:0002340 name: regulation of sexual behaviour def: "The mechanisms through which sexual behaviour is regulated." [ISBN:0-85199-313-3] is_a: IDOMAL:0002138 ! regulation of adult behaviour [Term] id: IDOMAL:0002341 name: responsiveness to host cue def: "Teneral females are unable to responde to host cues or take a blood meal, but during the first days after emergence their mouthparts and other organs become functional and they develop behavioural capabilities." [ISBN:0-85199-313-3] relationship: part_of IDOMAL:0002406 ! female sexual responsiveness [Term] id: IDOMAL:0002342 name: development of competence to respond to host cue def: "The development of the capability to respond to a variety of host stimuli." [ISBN:0-85199-313-3] relationship: part_of IDOMAL:0002341 ! responsiveness to host cue [Term] id: IDOMAL:0002343 name: effect of insemination def: "One effect is on the phase of the flight-activity rhythm.\nIt is suggested that a factor in the semen of the males of the autogenous strains suppressed blood-feeding by the nulliparous females of these strains.\nIn some species, virgin females are less responsive to host cues than inserminated females.\nAnother effect is the inhibition of responsiveness to host cues in females due to male accessory-gland secretion." [ISBN:0-85199-313-3] comment: The flight-activity periodicities of captive females of a number of crepuscular/nocturnal species changed, and came to resemble the periodicities of man-biting activity in wild populations. relationship: part_of IDOMAL:0002342 ! development of competence to respond to host cue relationship: part_of IDOMAL:0002386 ! onset of delayed inhibition of responsiveness [Term] id: IDOMAL:0002344 name: reserves of teneral adult def: "The fat body cells, or trophocytes, of fully grown larvae of Aedes aegypti and Culex pipiens are packed with lipid droplets, glycogen granules and vesicles which possibly contain protein, reserves which are carried over to the adult stage. The extent of the reserves depends upon the quality of larval nutrition, and there is some variability betweeen species in the proportions of glycogen and lipid. Unlike the higher Diptera, mosquito adults do not develop and 'adult fat body' differing in structure from that of the larvae. In well-nourished adults the fat body contains deposits of glycogen and lipid but no protein-containing vesicles." [ISBN:0-412-40180-0] is_a: IDOMAL:0002321 ! synthesis of reserves [Term] id: IDOMAL:0002345 name: aggregated distribution of larvae def: "In behavioural terms, aggregation is a congregation of animals that does not depend upon social attraction. Such behaviours are due to the fact that most habitats are not uniform." [ISBN:0-85199-313-3] comment: Aggregation is the irregular distribution of animals between habitats or, more usually, within habitats. Analysis of samples obtained from transects across a habitat reveals a clumped distribution if the ratio of variance to mean is significantly greater then one. is_a: IDOMAL:0002139 ! larval behavioural process [Term] id: IDOMAL:0002346 name: cannibalism def: "The attack and consumption of conspecific larvae of the same or an earlier instar." [ISBN:0-412-40180-0] is_a: IDOMAL:0002182 ! larval feeding behaviour [Term] id: IDOMAL:0002347 name: predator-avoidance behaviour def: "The presence of a predator has a damping effect on larvae movement. But at higher predator densities larval movement increased again slightly, possibly due to disturbance by the predators." [ISBN:0-85199-313-3] comment: Experiments were conductided with the usage of Aedes aegypti and Culex pipiens larvae and Notonecta undulata. is_a: IDOMAL:0002241 ! protective behaviour [Term] id: IDOMAL:0002348 name: protective coloration def: "The larvae and pupae of some culicuds are able to lighten or darken their body colour in accordance with the lightness or darkness of the background; others lack this ability." [ISBN:0-85199-313-3] is_a: IDOMAL:0002241 ! protective behaviour [Term] id: IDOMAL:0002349 name: using safe biotope def: "This is an important form of predator avoidance. A variety of relatively safe niches can be discerned among ground waters." [ISBN:0-85199-313-3] comment: Mosquito larval habitats fall into two distinct classes: Phytotelmata and ground waters. Phytotelmata are bodies of water held in or upon parts of terrestrial plants. The greatest variety of phytotelmata occurs in the tropics. Ground waters are also of many types but are predominantly still waters. Whereas most phytotelmata are enclosed water bodies, most natural ground waters are open. The activities of human populations result in the appearance of new habitats colonized by mosquitoes. is_a: IDOMAL:0002241 ! protective behaviour [Term] id: IDOMAL:0002350 name: allogrooming def: "The \"grooming\" of other individuals has been considered a form of aggresive behaviour and an aspect of feeding." [ISBN:0-85199-313-3] comment: It is unfortunate that we have little or no knowledge of the microorganisms and non-living, particulate matter abhering to the body surface of mosquito larvae in their natural habitats. is_a: IDOMAL:0002182 ! larval feeding behaviour relationship: part_of IDOMAL:0002183 ! grooming [Term] id: IDOMAL:0002351 name: akinesis def: "While in depth, a larva remains motionless, often when near or underneath a leaf." [ISBN:0-85199-313-3] is_a: IDOMAL:0002181 ! larval kinesis [Term] id: IDOMAL:0002352 name: regulation of pre-oviposition behaviour def: "Behavioural patterns of gravid females that result in arrival at potential oviposition sites and indicate the suitability of such sites are termed pre-oviposition behaviour." [ISBN:0-85199-313-3] is_a: IDOMAL:0002138 ! regulation of adult behaviour relationship: part_of IDOMAL:0002177 ! pre-oviposition behaviour [Term] id: IDOMAL:0002353 name: development of the alimentary canal def: "During growth the larval stage the alimentary canal grows in cell size and with the formation of polytene and endopolyploid nuclei." [ISBN:0-412-40180-0] is_a: IDOMAL:0002362 ! larval development [Term] id: IDOMAL:0002354 name: development of the antennal centre def: "The antennal centres grow slowly compared to the brain as a whole during the larval stage (k=0,8) and very rapidly about the time of larval-pupal ecdysis (k=4)." [ISBN:0-412-40180-0] is_a: IDOMAL:0002207 ! development of the central nervous system [Term] id: IDOMAL:0002355 name: development of the central body of the nervous system def: "The central body grows most actively in the 4th instar (k=2)." [ISBN:0-412-40180-0] is_a: IDOMAL:0002207 ! development of the central nervous system [Term] id: IDOMAL:0002356 name: development of the mushroom body def: "The mushroom bodies grow less strongly than the brain as a whole during the larval stage (k=0,5-0,9) but much more strongly in the pupal stage (k=1,8)." [ISBN:0-412-40180-0] is_a: IDOMAL:0002207 ! development of the central nervous system [Term] id: IDOMAL:0002357 name: immune response def: "Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat." [GO:0006955, ISBN:0-412-40180-0] comment: Mosquitoes are subject to parasitism by fungi, protists and nematodes. The most common response to organisms that penetrate into the haemocoele, and that are too large to be phagositized by single cells, is encapsulation of the intruders. Some protection against infection is provided by the cibarial armature. is_a: IDOMAL:0002443 ! immune system process [Term] id: IDOMAL:0002358 name: growth def: "The increase in size or mass of an entire organism, a part of an organism or a cell." [GO:0040007] synonym: "growth pattern" RELATED [] is_a: IDOMAL:0002112 ! physiological process of malaria vector created_by: elvira creation_date: 2007-11-28T03:00:00Z [Term] id: IDOMAL:0002359 name: phenol oxidase def: "The phenol oxidase enzymes are thought to be central to melanin formation. During encapsulation, polyphenol derivates probably cross-link with proteins from the haemolymph and haemocytes." [ISBN:0-12-473276-3] is_a: IDOMAL:0001034 ! abiotic relationship: participates_in IDOMAL:0002447 ! activation of phenol oxidase [Term] id: IDOMAL:0002360 name: encapsulation def: "In most arthropodes encapsulation is initiated when granular haemocytes degranulate upon contact with foreign bodies, and release components of a phenoloxidase-activating system which adhere to them. Plasmatocytes then enclose the foreign objects within an envelope of hihgly flattened cells which becomes pigmented." [ISBN:0-412-40180-0] synonym: "capsule formation" RELATED [ISBN:0-87081-411-7] is_a: IDOMAL:0002449 ! melanization defense response [Term] id: IDOMAL:0002361 name: process of ovulation def: "Ovulation is defined as the extrusion of mature oocytes from the ovarian follicles into the calyces and oviducts. Ovulated oocytes enter the vagina, from which they are extruded through the gonotreme at oviposition. Sperm penetrate an oocyte while it is within the vagina. Very soon after oviposition the oocyte chromosomes complete meiosis, and at that stage the oocyte is considered to have transformed into an egg." [ISBN:0-41211-490-0, ISBN:0-85199-313-3] is_a: IDOMAL:0002002 ! fiat process part of malaria vector relationship: part_of IDOMAL:0002160 ! reproduction created_by: elvira creation_date: 2007-11-27T12:21:00Z [Term] id: IDOMAL:0002362 name: larval development def: "The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of any animal when more or less of a metamorphosis takes place, before the assumption of the mature shape." [GO:0002164] is_a: IDOMAL:0002163 ! developmental process created_by: elvira creation_date: 2007-11-29T01:20:00Z [Term] id: IDOMAL:0002363 name: metamorphosis of the muscular system def: "Great changes take place in the muscular system during metamorphosis. Most larval head muscles are histolysed but some are carried over to the adult, developing the fine structure of adult muscle and aquiring new relationships with different parts of the head. New muscles arise and the sides and floor of the head become traversed by belts of small myoblasts whose origin is uncertain." [ISBN:0-412-40180-0] is_a: IDOMAL:0002170 ! metamorphosis [Term] id: IDOMAL:0002364 name: metamorphosis of the muscles of the thorax and abdomen def: "The muscles of the thorax and abdomen are carried over to the adult but the main part of the adult thoracic musculature is new, including the muscles of the appendages, largely formed within the imaginal buds, and the indirect flight muscles. The larval abdominal muscles degenerate early in adult life, having been used for swimming by the pupa and pharate adult. Movements of the adult abdomen are due to small adult muscles which develop from myoblasts in the pupa. Histolysis of the musculature, as of other organs, takes place entirely by autolysis and without the intervention of phagocytes." [ISBN:0-412-40180-0] is_a: IDOMAL:0002363 ! metamorphosis of the muscular system [Term] id: IDOMAL:0002365 name: sexual differentiation def: "Sexual dimorphism in adult mosquitoes is expressed in a number of ways: (i) in the structure of the gonads; (ii) in th eprimary sexual characters which are derived from the genital imaginal disks; and (iii) in secondary sexual characters such as the adult antennae, maxillary palps and body size. Innate behavioural differences between the sexes reflets dimorphism in the structure and function of the nervous system." [ISBN:0-412-40180-0] is_a: IDOMAL:0002163 ! developmental process created_by: elvira creation_date: 2007-11-30T10:57:00Z [Term] id: IDOMAL:0002366 name: kinetic response to food and dissolved nutrient def: "Mosquito larvae accumulate in regions where there is food because they make an orthokinetic response to soluble contituents diffusing from the food." [ISBN:0-85199-313-3] is_a: IDOMAL:0002370 ! kinetic response to an attractant relationship: part_of IDOMAL:0002245 ! direct orthokinesis [Term] id: IDOMAL:0002367 name: negative thigmokinesis def: "Inhibition of movement in response to contact stimuli." [ISBN:0-85199-313-3] comment: Observed in Anopheles messeae larvae. is_a: IDOMAL:0002181 ! larval kinesis [Term] id: IDOMAL:0002368 name: photokinesis def: "It has been observed in Anopheles maculipennis and Anopheles messeae larvae in the laboratory. If exposed to bright light, fourth instar larvae moved about incessantly at the water surface and dived frequently. When by chance they entered a shaded part of the container they became inactive; as a result, almost all larvae congregated in the shade." [ISBN:0-85199-313-3] is_a: IDOMAL:0002181 ! larval kinesis [Term] id: IDOMAL:0002369 name: kinetic response to an arrestant def: "Arrestant is substance that induces animals to remain in its presense through their undirected kinetic responses, either by stopping their locomotion (orthokinesis), or changing their rate of turning (klinokinesis)." [ISBN:0-85199-313-3] is_a: IDOMAL:0002242 ! kinetic response to chemical stimulus [Term] id: IDOMAL:0002370 name: kinetic response to an attractant def: "Attractan is substance that induces animals to make oriented movements towards its source." [ISBN:0-85199-313-3] is_a: IDOMAL:0002242 ! kinetic response to chemical stimulus [Term] id: IDOMAL:0002371 name: larval diving def: "A larva spontaneously separates itself from the water surface and descends with a swimming component." [ISBN:0-85199-313-3] is_a: IDOMAL:0002432 ! larval locomotion [Term] id: IDOMAL:0002372 name: larval gliding def: "A submerged larva, while feeding, moves anteriorly propelled by currents generated by the actions of its mouthparts." [ISBN:0-85199-313-3] is_a: IDOMAL:0002432 ! larval locomotion [Term] id: IDOMAL:0002373 name: chemotaxis def: "Tactic responses to chemical compounds." [ISBN:0-85199-313-3] is_a: IDOMAL:0002180 ! taxis [Term] id: IDOMAL:0002374 name: geotaxis def: "Tactical responses to gravitation." [ISBN:0-85199-313-3] is_a: IDOMAL:0002180 ! taxis [Term] id: IDOMAL:0002375 name: phototaxis def: "Tactic responses to light." [ISBN:0-85199-313-3] is_a: IDOMAL:0002180 ! taxis [Term] id: IDOMAL:0002376 name: thigmotaxis def: "Is described as a tendency to maintain bodily contact with solid objects." [ISBN:0-85199-313-3] comment: Anopheles larvae exhibit this behaviour. In fact, they exhibit negative thigmotaxis; locomotion is reduced by contact with a solid object. is_a: IDOMAL:0002180 ! taxis [Term] id: IDOMAL:0002377 name: ultrastructural changes in the Trophocytes def: "During successive ovarian cycles the fat body passes through a parallel series of cyclesof ultrastructural generation and degeneration, during each of which the fat body cells or trophocytes exhibit three stages: (i) A previtellogenic stage of activity. (ii) A vitellogenic stage. (iii) A termination stage." [ISBN:0-412-40180-0] is_a: IDOMAL:0002112 ! physiological process of malaria vector relationship: part_of IDOMAL:0002034 ! vitellogenesis [Term] id: IDOMAL:0002378 name: previtellogenic development def: "In newly emerged females the cytoplasm of each trophocyte was rich in reserves, containing lipid droplets, glycogen bodies, and three types of membrane-bounded protein granule." [ISBN:0-412-40180-0] comment: During the first three days after emergence the nucleolus grew >3-fold and its enlarging granular component came to contain many maturing pre-ribosomes. The number of ribosomes in the cytoplasm increased sharply. Rough endoplasmic reticulum appeared in the form of cisternae,located in rows, Conentric circles or round lipid inclusions. The Golgi complexes developed into well-defined organelles consisting of small vesicles, 3-4 short vesicular cisternae, and a few larger vesicles. The plasma membrane bacame extended into numerous infoldings, increasing its surface area. is_a: IDOMAL:0002112 ! physiological process of malaria vector relationship: part_of IDOMAL:0002377 ! ultrastructural changes in the Trophocytes [Term] id: IDOMAL:0002379 name: vitellogenic stage def: "During this stage, the nucleolus became more multilobed, ribosome proliferation had been renewed, and the rough endoplasmic reticulum was undergoin reorganization." [ISBN:0-412-40180-0] is_a: IDOMAL:0002112 ! physiological process of malaria vector relationship: part_of IDOMAL:0002377 ! ultrastructural changes in the Trophocytes relationship: preceded_by IDOMAL:0002378 ! previtellogenic development [Term] id: IDOMAL:0002380 name: termination stage def: "Termination of vitellogenin synthesis starts with a sharp decline in the concentration of vitellogenin in the fat body. This decline is thought to be associated with a simultaneous and dramatic rise in lysosomal activity." [ISBN:0-412-40180-0] comment: Ultrastructural studies showed that two processes were involved: (i) autophagy, which involved the sequestration of organelles by isolation membranes, followed by fusion of the so-formed isolation body with primary lysosomes; and (ii) crinophagy, which involved the direct fusion of organelles with primary lysosomes. is_a: IDOMAL:0002112 ! physiological process of malaria vector relationship: part_of IDOMAL:0002377 ! ultrastructural changes in the Trophocytes relationship: preceded_by IDOMAL:0002379 ! vitellogenic stage [Term] id: IDOMAL:0002381 name: stimulation of vitellogenin synthesis def: "During the privitellogenic phase of each ovarian cycle the fat body is made competent for vitellogenin synthesis. Stimulated by juvenile hormone, the trophocytes bacame polyploid and their nucleoli enlarge." [ISBN:0-412-40180-0] is_a: IDOMAL:0002112 ! physiological process of malaria vector relationship: part_of IDOMAL:0002035 ! vitellogenin synthesis [Term] id: IDOMAL:0002382 name: termination of vitellogenin synthesis def: "The mechanism regulating termination of vitellogenin synthesis remains to be fully elucidated. Lysosomal degradation causes the termination but whether this is programmed solely by the fat body or whether other factors are involved remain uncertain." [ISBN:0-412-40180-0] relationship: part_of IDOMAL:0002035 ! vitellogenin synthesis [Term] id: IDOMAL:0002383 name: free-running of rhythm def: "Flight-activity periodicties that had been entrained by photoperiod free-ran in DD or LL, and therefore were endogenously controlled rhythms. The same was observed for the erection of male antennal fibrillae and male responsiveness to the female flight tone, for the responsiveness of females to host cues, and for oviposition activity." [ISBN:0-85199-313-3] relationship: part_of IDOMAL:0002392 ! adult circadian rhythm [Term] id: IDOMAL:0002384 name: compulsive killing def: "When kept with prey in small containers, Toxorhynchites fourth instar larvae that have reached an advanced stage of development stop feeding but continue killing." [ISBN:0-85199-313-3] is_a: IDOMAL:0002139 ! larval behavioural process [Term] id: IDOMAL:0002385 name: onset of immediate inhibition of responsiveness def: "Culicine females that have engorged fully usually become inactive and non-responsive to host cues." [ISBN:0-85199-313-3] comment: When females of Aedes aegypti were exposed to host odour within 1h of taking a blood meal, those that imbibed 2,5 micro litre blood, or less, remained fully responsive. Responsiveness was negatively correlated with bloodmeal volume within the range 2.5-4 micro litre. is_a: IDOMAL:0002341 ! responsiveness to host cue [Term] id: IDOMAL:0002386 name: onset of delayed inhibition of responsiveness def: "Non-immediate blocking of responsiveness to host cues. Females remained responsive to host odour for 24h after receiving a 1 micro litre blood enema." [ISBN:0-85199-313-3] comment: Ovary development occured in many of these females, and from about 30 h after receiving the enema, those that developed ovaries failed to respond to host odour.\nThe onset and termination of delayed inhibiton are affected by insemination and ovipostion, and the mechanisms that regulate it involve haemolymph-borne factors. is_a: IDOMAL:0002341 ! responsiveness to host cue [Term] id: IDOMAL:0002387 name: responsiveness of lactic acid-sensitive neurones def: "The reversible change in sensitivity of the lactic acid-sensitive neurones can account for the switching between host-finding and non-host-finding." [ISBN:0-85199-313-3] relationship: part_of IDOMAL:0002386 ! onset of delayed inhibition of responsiveness [Term] id: IDOMAL:0002388 name: effect of 20-hydroxyecdysone def: "Injection of picorgram quantities of 20-hydroxyecdysone into ovariectomized females of Aedes aegypti after blood-feeding caused a significant decrease in responsiveness to host cues when tested 72 h after blood-feeding, provided the females had been inseminated and were not deprived of sucrose." [ISBN:0-85199-313-3] relationship: part_of IDOMAL:0002386 ! onset of delayed inhibition of responsiveness [Term] id: IDOMAL:0002389 name: fat body factor def: "The fat body is the source of a factor that can induce the reduction in sensitivity of the LA-excited neurones." [ISBN:0-85199-313-3] comment: That the fat body can be the source of such a factor was shown by transplanting, into sugar-fed females, fat body from females that had blood-fed 24 h previously. Twenty-four hours later the recipintes lacked highly sensitive LA-excited neurones, and had become significantly less responsive to host odour. We do not know what factor acts directly on the LA-excited neurones. relationship: part_of IDOMAL:0002386 ! onset of delayed inhibition of responsiveness [Term] id: IDOMAL:0002390 name: recovery of responsiveness to host cue def: "The return of sensitivity to host cues." [ISBN:0-85199-313-3] is_a: IDOMAL:0002341 ! responsiveness to host cue [Term] id: IDOMAL:0002391 name: onset of activity in crepuscular species def: "For species that become active around sunset, it is possible that the time at which acticity starts is governed by (i) zenith light intensity; (ii) the angle of the sun; (iii) time in relation to sunset." [ISBN:0-85199-313-3] is_a: IDOMAL:0002437 ! process_boundary [Term] id: IDOMAL:0002392 name: adult circadian rhythm def: "The outward expression of an internal oscillator system that entrains to significant 24h oscillations in the external environment." [ISBN:0-85199-313-3] comment: The activity patterns of wild mosquitoes have a phase relationship with the natural cycle of light and darkness. The times of activity of some species fall within the hours of daylight, those of other species during twilight or during the hours of darkness. is_a: GO:0048511 ! rythmic process relationship: part_of IDOMAL:0002141 ! adult behavioural process [Term] id: IDOMAL:0002393 name: behaviour of crepuscular and nocturnal species def: "Among species that show crepuscular/nocturnal activity, some are most active for brief periods at dusk or at dusk and dawn." [ISBN:0-85199-313-3] comment: It may be that, in nature, the gradual changes in light intensity around sunset and dawn play some part in the expression of activity at those times; however, the persistance E, M and Nd peaks in constant darkness and in constant dim light shows that endogenous mechanisms are involved. is_a: IDOMAL:0002141 ! adult behavioural process [Term] id: IDOMAL:0002394 name: behaviour of male and virgin female def: "The behaviours of male and virgin female mosquitoes relate principally to mating and feeding on plant juices. Flight periodicities recorded in the laboratory for four species were characterized by bursts of activity at dusk and, to a lesser extent, dawn with scotophase activity present or not, according to species." [ISBN:0-85199-313-3] is_a: IDOMAL:0002393 ! behaviour of crepuscular and nocturnal species [Term] id: IDOMAL:0002395 name: behaviour of inseminated non-blood-fed female def: "In the laboratory, in most of the four nocturnal/crepuscular species investigated, insemination led to a reduction in the E and M flight-activity peaks shown by virgin femlaes and an increase in scotophase activity. Such a periodicity was characteristic of wild females of all these species taken in biting catches." [ISBN:0-85199-313-3] is_a: IDOMAL:0002393 ! behaviour of crepuscular and nocturnal species [Term] id: IDOMAL:0002396 name: behaviour of blood-fed, gravid and parous female def: "Inseminated females that have taken a full blood meal are characteristically inactive during the first stages of vitellogenesis, although they may fly to obtain nectar. Flight activity is resumed once they are gravid." [ISBN:0-85199-313-3] is_a: IDOMAL:0002393 ! behaviour of crepuscular and nocturnal species [Term] id: IDOMAL:0002397 name: behaviour of diurnal species def: "WIld females exhibit peaks of alighting on vertebrate hosts and of oviposition at the beginning and end of the photophase. Captive females show a similar bimodal pattern with regard to flight activity, sugar feeding, response to host odour, and oviposition. When continuously exposed to sugar or host odour captive females showed significant levels of activity throughout the scotophase." [ISBN:0-85199-313-3] is_a: IDOMAL:0002141 ! adult behavioural process [Term] id: IDOMAL:0002398 name: effect of simulated crepuscular conditions and moonlight def: "Photoperiods with abrupt transitions of light intensity between the L and D phases induced slightly different periodicities from those of photoperiods with gradual transitions. Abrupt light-ons induced an apparent startle response. In constant dim light within the intensity range of moonlight, flight activity was more intense than in constant darkness." [ISBN:0-85199-313-3] relationship: part_of IDOMAL:0002392 ! adult circadian rhythm [Term] id: IDOMAL:0002399 name: effect of insemination in the adult circadian rhythm def: "A rhythm-modifying factor that is transferred to the female during copulation induces changes in the pattern of flight-activity periodicities." [ISBN:0-85199-313-3] relationship: part_of IDOMAL:0002392 ! adult circadian rhythm [Term] id: IDOMAL:0002400 name: feeding on plant sugar def: "The sugars in plant fluids are an extensively used energy source for both males and females. Mosquitoes also obtain plant-derived sugars from other insects and their excretions. Plant fluids provide both sugars and water, and are an important component of mosquito nutrition." [ISBN:0-85199-313-3] is_a: IDOMAL:0002062 ! sugar feeding [Term] id: IDOMAL:0002401 name: flower visiting def: "Investigations of flower visiting in mosquitoes in particular habitats, and conducted throughout the diel, showed that the mosquitoes imbibed nectar from some plant species but not from others." [ISBN:0-85199-313-3] relationship: part_of IDOMAL:0002400 ! feeding on plant sugar [Term] id: IDOMAL:0002402 name: insect source def: "Acquiring plant sugars from other insects." [ISBN:0-85199-313-3] is_a: IDOMAL:0002062 ! sugar feeding [Term] id: IDOMAL:0002403 name: honeydew def: "The excretory product of many Homoptera, honeydew, provides a food source for adult Diptera, which secrete saliva on to the dry deposits and imbibe the dissolved sugars." [ISBN:0-85199-313-3] is_a: IDOMAL:0002402 ! insect source [Term] id: IDOMAL:0002404 name: ant as a sugar source def: "Adult female mosquitoes of the sabethine genus Malaya have evolved a remarkable manner of acquiring fluids of plant origin: they imbibe fluid regurgitated by ants of the genus Crematogaster. The habit has not been described for males." [ISBN:0-85199-313-3] is_a: IDOMAL:0002402 ! insect source [Term] id: IDOMAL:0002405 name: diel periodicity of sugar feeding def: "All measurements of the intensities of nectar feeding that have been made over periods of days revealed diel periodicities." [ISBN:0-85199-313-3] comment: The times at which species fed on nectar tended to coincide with those at which they displayed other activities, i.e. individual species were consistently diurnal, crepuscular or nocturnal. This alone suggests that an endogenous rhythm underlies the timing of sugar feeding. relationship: part_of IDOMAL:0002400 ! feeding on plant sugar [Term] id: IDOMAL:0002406 name: female sexual responsiveness def: "The females of most mosquito species are sexually unreceptive during the first 30-60h of adult life. During this period they may couple with males but do not become inseminated." [ISBN:0-85199-313-3] is_a: IDOMAL:0002174 ! sexual behaviour relationship: part_of IDOMAL:0002267 ! sexual responsiveness and refractoriness relationship: part_of IDOMAL:0002340 ! regulation of sexual behaviour [Term] id: IDOMAL:0002407 name: orientation towards the source of an odour plume def: "Mosquitoes are capable of odour-mediated, optomotor-guided navigation upwind, and experimentation has shown that the females of certain species respond to odour emanating from hosts 22 or 36 m distant." [ISBN:0-85199-313-3] is_a: IDOMAL:0002304 ! response to host odour [Term] id: IDOMAL:0002408 name: response to stimulus born by convection current def: "Female mosquitoes respond to warm dry air rising from a heated dish, but respond much more strongly to a human hand. Undoubtedly, convection currents that rise from warm-blooded animals carry such constituents of host odour as water vapour, CO2 and organic volatiles." [ISBN:0-85199-313-3] is_a: GO:0050896 ! response to stimulus [Term] id: IDOMAL:0002409 name: extrinsic incubation period def: "The period from ingestion of the infectious blood meal to transmission capability." [ISBN:0-12-473276-3] is_a: IDOMAL:0000092 ! temporal region [Term] id: IDOMAL:0002410 name: approach of oviposition site def: "The behavioural pattern of mosquitoes when choosing where to deposit their eggs." [ISBN:0-85199-313-3] relationship: part_of IDOMAL:0002427 ! egg laying behaviour [Term] id: IDOMAL:0002411 name: osmotic and ionic regulation def: "Mosquito larvae are found in a wide range of habitats, from rain-filled pools and containers at one extreme to inland saline pools of high salinity, high alkalinity and unusual ionic composition at the other. The capacity to survive under one or other, or even both, of these extreme conditions is due to powerful transport processes in the epithelia of the alimentary canal and anal papillae which provide homeostasis of the internal environment, making mosquito larvae among the best ionic and osmotic regulators in the animal kingdom." [ISBN:0-412-40180-0] is_a: IDOMAL:0002442 ! regulation of biological process [Term] id: IDOMAL:0002412 name: regulation of the haemolymph def: "Fluxes immediately bear upon the haemolymph, but the larvae can regulate the composition of their haemolymph to within narrow limits." [ISBN:0-412-40180-0] comment: All species appear able to regulate when in fresh water, some can regulate in fresh and brackish water, and a few in fresh and highly saline water. is_a: IDOMAL:0002411 ! osmotic and ionic regulation [Term] id: IDOMAL:0002414 name: nodule formation def: "Nodules appear as compacted masses of bacteria enmeshed wih hemocytes, the whole of which usually becomse infiltrated with the pigment melanin. Many nodules are then walled off under a final layer of hemocytes." [ISBN:0-12-473276-3, ISBN:0-87081-411-7] comment: Although small infections with bacteria are dealt with through phagocytosis, the response to more overwhelming infections is nodule formation. is_a: IDOMAL:0002450 ! melanotic encapsulation [Term] id: IDOMAL:0002415 name: cell-to-cell communication def: "Communication between similar or different cells through a variety of mediators, like cytokines." [ISBN:0-87081-411-7] is_a: IDOMAL:0002002 ! fiat process part of malaria vector relationship: part_of IDOMAL:0002360 ! encapsulation [Term] id: IDOMAL:0002416 name: adult circa-bi-dian rhythm def: "A biological rhythm with a natural period of about 48 h." [ISBN:0-85199-313-3] is_a: GO:0048511 ! rythmic process relationship: part_of IDOMAL:0002141 ! adult behavioural process [Term] id: IDOMAL:0002417 name: response to emanations from larva and pupa def: "Some gravid mosquitoes oviposit preferentially on water that previously contained larvae, pupae, exuviae or emerging adult, this was ascribed to chemical factors produced by them. Those factors are classed as pheromones by some authors." [ISBN:0-85199-313-3] is_a: IDOMAL:0002309 ! response to chemical cue during pre-oviposition stage and oviposition [Term] id: IDOMAL:0002418 name: ovulation def: "The extrusion of mature oocytes from the ovarian follicles into the calyces and oviducts." [ISBN:0-81599-313-3] is_a: IDOMAL:0002319 ! egg laying [Term] id: IDOMAL:0002419 name: previtellogenic arrest def: "An imoprtant adaptation of anautogeny is the establishment of previtellogenic developmental arrest preventing the activation of YPP genes in previtellogenic competent females prior to blood feeding." [ISBN:0-12-473276-3] relationship: part_of IDOMAL:0002247 ! anautogeny [Term] id: IDOMAL:0002420 name: expression of fixed action patterns def: "Specific behaviors programmed into the central nervous system (CNS), which when released at appropriate times provide a selective advantage to those individuals expressing them." [ISBN:0-12-473276-3] is_a: IDOMAL:0002125 ! nervous system process [Term] id: IDOMAL:0002421 name: compound eye def: "The eye of a vector organisms, which is composed of many light-sensitive elements, each having its own refractive system and each forming a portion of an image." [KL:KL] is_a: IDOMAL:0002458 ! anatomical structure created_by: Pantelis creation_date: 2009-07-12T11:32:53Z [Term] id: IDOMAL:0002422 name: male terminalia rotation def: "Male mosquitoes eclose with genitalia that are imporperly positioned for mating. Before they are able to successfully copulate, their terminalia must rotate through 180 degrees, either clockwise or counterclockwise." [ISBN:0-12-473276-3] is_a: IDOMAL:0002163 ! developmental process [Term] id: IDOMAL:0002423 name: flight metabolism def: "Insect flight muscle is the most metabolically active tissue known. Flight can be powered by sugar, lipid or proline metabolism." [ISBN:0-13-473276-3] is_a: IDOMAL:0002162 ! adult energy metabolism [Term] id: IDOMAL:0002424 name: release of 20-hydroxyecdysone def: "The rise in 20-hydtroxyecdysone levels after the blood meal stimulates the vitellogenic phase of development." [ISBN:0-13-473276-3] is_a: IDOMAL:0002112 ! physiological process of malaria vector relationship: part_of IDOMAL:0002034 ! vitellogenesis [Term] id: IDOMAL:0002425 name: encapsulation response to protozoan parasite def: "The occurence of melanized ookinetes, oocysts and sporozoites within the salivary glands. Also ookinetes are encapsulated betweent he basal lamina of the midgut and the midgut epithelial cells and are not directly in the hemocoel." [ISBN:0-12-473276-3] is_a: IDOMAL:0002449 ! melanization defense response [Term] id: IDOMAL:0002426 name: acellular encapsulation def: "Capsules take the form of a sheath of melanin deposited on the surface of foreign objects." [ISBN:0-13-473276-3] comment: It occurs primarily among certain nematoceran Diptera, e.g. , mosquitoes, sand flies. synonym: "humoral encapsulation" RELATED [ISBN:0-12-473276-3] synonym: "humoral melanization" RELATED [ISBN:0-12-473276-3] is_a: IDOMAL:0002450 ! melanotic encapsulation [Term] id: IDOMAL:0002427 name: egg laying behaviour def: "The behavioural events leading to oviposition by a gravid mosquito. They usually follow the sequence: ranging flight, orientation, encounter and acceptance." [ISBN:0-85199-313-3] is_a: IDOMAL:0002141 ! adult behavioural process relationship: part_of IDOMAL:0002319 ! egg laying [Term] id: IDOMAL:0002428 name: development of the genital imaginal disk def: "In Aedes stimulans larvae of both genotypes an imaginal disk appears, during the 3rd instar, as a medial pair of epidermal thickenings in the posteroventral region of the 8th abdominal segment. During the first half of the 4th instar cell division occurs in these thickenings and in the area between them, and the disk develops into two lateral podal buds and a median plate." [ISBN:0-412-40180-0] is_a: IDOMAL:0002205 ! imaginal disk development [Term] id: IDOMAL:0002429 name: courtship def: "Male display of specialized behaviour patterns that overcome female unreceptiveness and form the normal preliminaries to copulation." [ISBN:0-85199-313-3] is_a: IDOMAL:0002141 ! adult behavioural process relationship: part_of IDOMAL:0002000 ! mating [Term] id: IDOMAL:0002430 name: turnover of transductive membrane def: "The repeated restructuration of the light sensitive membrane through a cycle of degradation and renewal which is synchronous with the natural diel cycle of illlumination." [ISBN:0-85199-313-3] relationship: part_of IDOMAL:0002185 ! larval vision [Term] id: IDOMAL:0002431 name: humoral response to filarial worms def: "Recognition of the microfilariae within the hemocoele triggers a humoral immune response that may result in melanotic encapsulation." [ISBN:0-12-473276-3] is_a: IDOMAL:0002357 ! immune response [Term] id: IDOMAL:0002432 name: larval locomotion def: "The assortment of movements of mosquito larvae." [ISBN:0-85199-313-3] is_a: IDOMAL:0002114 ! locomotion relationship: part_of IDOMAL:0002139 ! larval behavioural process [Term] id: IDOMAL:0002433 name: movement within an odour plume def: "Upon entering an odour plume, mosquitoes continue to fly in a straight line. But if the subsequentely leave the plume they engage in rapid turns, a strategy that presumably increases the probability that they will reenter the plume or a neighboring one." [ISBN:0-12-473276-3] is_a: IDOMAL:0002242 ! kinetic response to chemical stimulus relationship: part_of IDOMAL:0002304 ! response to host odour [Term] id: IDOMAL:0002434 name: regulation of larval behaviour def: "Any process that modulates the behavioural patterns of larvae." [ISBN:0-12-473276-3] comment: Knowledge of larval behaviour is essential to predicting where the insects are most likely to be found for purposes of census and management. It is important to understand when, where and how immatures feed when attempting to control them with microbial agents. is_a: IDOMAL:0002442 ! regulation of biological process relationship: part_of IDOMAL:0002139 ! larval behavioural process [Term] id: IDOMAL:0002435 name: regulation of larval feeding behaviour def: "The rate of food ingestion by larvae is generally enhanced by yeast extracts, nucleotides and generatl viscosity of the water. Temperature of water, larval instar and prior starvation also influence feeding rates. Larvae may also aggregate in response to gradients of temperature and nutrients within the water." [ISBN:0-12-473276-3] is_a: IDOMAL:0002434 ! regulation of larval behaviour [Term] id: IDOMAL:0002436 name: regulation of alarm behaviour def: "Differences in the response thresholds of larvae are heritable and can be modified by their nutritional state. Larvae that are maintained on a suboptimal diet are less likely to display the alarm response when stimulated by light." [ISBN:0-12-473276-3] is_a: IDOMAL:0002434 ! regulation of larval behaviour [Term] id: IDOMAL:0002437 name: process_boundary def: "A processual entity [span:ProcessualEntity] that is the fiat or bona fide instantaneous temporal process boundary." [SPAN:process_boundary] created_by: Pantelis creation_date: 2009-07-12T11:48:42Z [Term] id: IDOMAL:0002438 name: regulation of circadian rhythmicity def: "The rhythms are generally entrained by photoperiod and temperature and appear to be governed by multiple endogenous circadian pacemakers. Females that have mated often show an altered periodicity that eliminates the acitivity peak normally associated with the time of day that mating occurs." [ISBN:0-12-473276-3] is_a: IDOMAL:0002442 ! regulation of biological process relationship: part_of IDOMAL:0002392 ! adult circadian rhythm [Term] id: IDOMAL:0002439 name: amino acid absorption def: "Once the proteins have been degraded to their constituent amino acids in the lumen of the gut, they must be absorbed by the midgut epithelial cells and transferred to the haemolymph, from which they can be taken up by the fat body and other tissues." [ISBN:0-12-473276-3] is_a: IDOMAL:0002032 ! absorption of the products of digestion [Term] id: IDOMAL:0002440 name: carbohydrate absorption def: "Insects use a unique mechanism to create a concentration gradient in glucose betweent he midgut lumen and the haemolymph taht ensures efficient passive transport." [ISBN:0-12-473276-3] is_a: IDOMAL:0002032 ! absorption of the products of digestion [Term] id: IDOMAL:0002441 name: lipid absorption def: "Several species accumulate fat droplets in midgut cells during blood meal digestion, but the origin of this lipid is unclear." [ISBN:0-12-473276-3] comment: Nothing is known about the mechanism of lipid absorption in insects. is_a: IDOMAL:0002032 ! absorption of the products of digestion [Term] id: IDOMAL:0002442 name: regulation of biological process def: "Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GO:0050789] is_a: IDOMAL:0002112 ! physiological process of malaria vector [Term] id: IDOMAL:0002443 name: immune system process def: "Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats." [GO:0002376] is_a: IDOMAL:0002112 ! physiological process of malaria vector [Term] id: IDOMAL:0002444 name: activation of immune response def: "For a defense response to be triggered by an infected organism, the pathogen has to be detected and self-damage avoided by distinguishing it from self-tissues." [ISBN:0-12-473276-3] is_a: IDOMAL:0002443 ! immune system process [Term] id: IDOMAL:0002445 name: pathogen recognition molecule def: "Several types of insect plasma proteins have been shown to function as pattern-recognition molecules. They bind to one or more polysaccharide or lipopolysaccharide components on the surface of microbial cells. These interactions stimulate immune responses, such as phagocytosis, nodule formation and phenol oxidase activation." [ISBN:0-12-473276-3] is_a: IDOMAL:0001034 ! abiotic relationship: participates_in IDOMAL:0002444 ! activation of immune response [Term] id: IDOMAL:0002446 name: activation of proteolytic cascade def: "The process of sequential activation of multiple proteases and other substrates, ultimately resulting in localized and highly regulated responses." [ISBN:0-12-473276-3] is_a: IDOMAL:0002153 ! vector metabolic process relationship: part_of IDOMAL:0002357 ! immune response [Term] id: IDOMAL:0002447 name: activation of phenol oxidase def: "After pathogen recognition proteolytic processing of pro-phenoloxidase activating enzyme (proPPAE) generates actve PPAE, which in turn cleaves pro-phenoloxidase (proPO) to active phenol oxidase. Phenol oxidase catalyzes the conversion of tyrosine to dopa, which is converted to dopamine by dopa decarboxylase (DDC)." [ISBN:0-12-473276-3] is_a: IDOMAL:0002153 ! vector metabolic process relationship: part_of IDOMAL:0002446 ! activation of proteolytic cascade [Term] id: IDOMAL:0002448 name: regulation of proteolytic cascade def: "The immune responses activated by proteases are regulated in vivo to limit them to localized areas and to protect the host from harmful effects of overstimulation of the immune system. In arthropods, as in mammals, serpins are used for regulation." [ISBN:0-12-473276-3] is_a: IDOMAL:0002442 ! regulation of biological process relationship: part_of IDOMAL:0002446 ! activation of proteolytic cascade [Term] id: IDOMAL:0002449 name: melanization defense response def: "The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin." [GO:0035006] synonym: "melanization defence response" RELATED [GO:0035006] is_a: IDOMAL:0002357 ! immune response [Term] id: IDOMAL:0002450 name: melanotic encapsulation def: "Encapsulation is a common immune reaction in insects against parasites or pathogens taht can also be induced by injection of expermental materials into the hemocoel. Cellular encapsulation can occur in two forms: (1) as nodule formation against small particulate material (e.g., bacteria), and (2) as capsule formation, which often occurs if the foreign object exceeds the size of phagocytic hemocytes." [ISBN:0-12-473276-3] is_a: IDOMAL:0002360 ! encapsulation [Term] id: IDOMAL:0002451 name: capsule formation def: "It occurs in its simplest form when a large foreign object becomes covered by certain types of hemocytes, which eventually form flattened layers completely enclosing the object." [ISBN:0-12-473276-3] is_a: IDOMAL:0002450 ! melanotic encapsulation [Term] id: IDOMAL:0002452 name: response to microfilarial worm def: "The worms are enclosed in an acellular layer of melanin, perhaps with the active participation of hemocytes. Subsequently, hemocyte adherence occurs, resulting in a single-layered cellular capsule over the melanized core." [ISBN:0-12-473276-3] is_a: IDOMAL:0002449 ! melanization defense response [Term] id: IDOMAL:0002453 name: growth of the alimentary canal def: "During the larval stage the alimentary canal grows by increase in cell size and with the formation polytene and endopolyploid nuclei." [ISBN:0-412-40180-0] is_a: IDOMAL:0002358 ! growth created_by: elvira creation_date: 2007-11-30T12:35:00Z [Term] id: IDOMAL:0002454 name: hormone secretion def: "The release of hormones, substances with a specific regulatory effect on a particular organ or group of cells." [GO:0046879] relationship: part_of IDOMAL:0002129 ! endocrine system process created_by: elvira creation_date: 2007-12-03T12:45:00Z [Term] id: IDOMAL:0002455 name: adult locomotion def: "The assortment of movements of the adult mosquito." [ISBN:0-85199-313-3] is_a: IDOMAL:0002114 ! locomotion [Term] id: IDOMAL:0002456 name: catabolic process def: "The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism." [GO:0009056] synonym: "breakdown" EXACT [GO:0009056] synonym: "catabolism" EXACT [GO:0009056] synonym: "degradation" EXACT [GO:0009056] is_a: IDOMAL:0002153 ! vector metabolic process [Term] id: IDOMAL:0002458 name: anatomical structure def: "Material anatomical entity that has inherent 3D shape and is generated by coordinated expression of the organism's own genome." [CARO:0000003] xref: CARO:0000003 is_a: IDOMAL:0000343 ! biotic created_by: Pantelis creation_date: 2009-07-12T07:43:37Z [Term] id: IDOMAL:0002459 name: anatomical group def: "Anatomical structure consisting of at least two non-overlapping organs, multi-tissue aggregates or portion of tissues or cells of different types that does not constitute an organism, organ, multi-tissue aggregate, or portion of tissue." [CARO:0000054] xref: CARO:0000054 is_a: IDOMAL:0002458 ! anatomical structure created_by: Pantelis creation_date: 2009-07-12T07:44:56Z [Term] id: IDOMAL:0002460 name: anatomical system def: "Anatomical group that is has as its parts distinct anatomical structures interconnected by anatomical structures at a lower level of granularity." [CARO:0000011] xref: CARO:0000011 is_a: IDOMAL:0002459 ! anatomical group created_by: Pantelis creation_date: 2009-07-12T07:46:28Z [Term] id: IDOMAL:0002461 name: anatomical cluster def: "Anatomical group that has its parts adjacent to one another." [CARO:0000041] xref: CARO:00000041 is_a: IDOMAL:0002459 ! anatomical group created_by: Pantelis creation_date: 2009-07-12T07:49:15Z [Term] id: IDOMAL:0002462 name: adult locomotion behaviour def: "A process of locomotion during the adult stage of a vector organism." [KL:KL] is_a: IDOMAL:0002141 ! adult behavioural process relationship: part_of IDOMAL:0002455 ! adult locomotion created_by: Pantelis creation_date: 2009-07-12T10:42:01Z [Term] id: MIRO:00000001 name: Rdl A296S def: "Resistance-associated point mutation of amino acid at position 296 in the insecticide target GABA receptor gene product causing a structural change and decreased response to the insecticide." [KL:KL] is_a: MIRO:00000115 ! modified GABA receptor [Term] id: MIRO:00000002 name: deficiency of midgut receptor def: "Loss of function of specific midgut receptors." [PT:PT] relationship: agent_in MIRO:00000129 ! midgut receptor mediated resistance [Term] id: MIRO:00000003 name: metabolic resistance def: "Class of insecticide resistance that relies on the biochemical transformation of the insecticide, ultimately reducing its capacity to interact with a target molecule." [PMID:16925478 "Li et al. (2007), Ann Rev Entomol, 52: 231"] synonym: "Detoxification" RELATED [] is_a: MIRO:00000021 ! resistance to single insecticide [Term] id: MIRO:00000004 name: target-site resistance def: "Resistance caused by a structural change of the insecticide target gene product leading to decreased response to the insecticide." [KL:KL] is_a: MIRO:00000021 ! resistance to single insecticide [Term] id: MIRO:00000005 name: behavioural resistance def: "Resistance due to a modification in insect behaviour that helps it avoid the lethal effect of insecticides." [KL:KL] is_a: MIRO:00000021 ! resistance to single insecticide [Term] id: MIRO:00000006 name: reduced penetration def: "Modification(s) in the insect cuticle preventing or slowing the absorption or penetration of insecticide." [IRAC:manual "IRAC manual"] xref: IRAC:manual "IRAC manual" is_a: MIRO:00000077 ! cuticle permeability related resistance [Term] id: MIRO:00000007 name: stimulus dependent resistance def: "Resistance due to a chemical-dependent modification in insect behaviour that helps it avoid the lethal effect of insecticides (e.g. repellance)." [KL:KL] is_a: MIRO:00000005 ! behavioural resistance [Term] id: MIRO:00000008 name: Kdr V1016G def: "Resistance-associated point mutation of amino acid at position 1016 (V-G) in the insecticide target sodium channel gene product causing a structural change and decreased response to the insecticide." [KL:KL] is_a: MIRO:00000113 ! modified sodium channel [Term] id: MIRO:00000009 name: Kdr V1016I def: "Resistance-associated point mutation of amino acid at position 1016 (V-I) in the insecticide target sodium channel gene product causing a structural change and decreased response to the insecticide." [KL:KL] is_a: MIRO:00000113 ! modified sodium channel [Term] id: MIRO:00000010 name: Kdr I1011M def: "Resistance-associated point mutation of amino acid at position 1011 (I-M) in the insecticide target sodium channel gene product causing a structural change and decreased response to the insecticide." [KL:KL] is_a: MIRO:00000113 ! modified sodium channel [Term] id: MIRO:00000011 name: Kdr I1011V def: "Resistance-associated point mutation of amino acid at position 1011 (I-V) in the insecticide target sodium channel gene product causing a structural change and decreased response to the insecticide." [KL:KL] is_a: MIRO:00000113 ! modified sodium channel [Term] id: MIRO:00000012 name: carboxysterase resistance def: "Metabolic resistance due to qualitative or quantitative changes in COE gene products (group of hydrolase enzymes capable of hydrolyzing compounds containing ester bonds) resulting in more efficient insecticide sequestration or metabolism." [IRAC:manual "IRAC manual", PMID:16925478 "Li et al. (2007), Ann Rev Entomol, 52: 231"] synonym: "COE resistance" EXACT [] xref: PMID:16925478 "Li et al. (2007), Ann Rev Entomol, 52: 231" is_a: MIRO:00000003 ! metabolic resistance [Term] id: MIRO:00000013 name: COE quantitative change def: "A change of the COE activity; the resulting metabolic resistance is due to up-regulated COE gene products, which more efficiently sequester or metabolize insecticides." [KL:KL] synonym: "COE upregulation" EXACT [] relationship: agent_in MIRO:00000012 ! carboxysterase resistance [Term] id: MIRO:00000014 name: Glutathione S-transferase resistance def: "Metabolic resistance due to quantitative or qualitative changes in GST gene products (phase II metabolic enzymes capable of conjugating reduced glutathione to the electrophilic centers of exogenous and endogenous compounds) resulting in more efficient insecticide detoxification." [PMID:16925478 "Li et al. (2007), Ann Rev Entomol, 52: 231"] synonym: "GSH S-transferase resistance" EXACT [] synonym: "GST resistance" EXACT [] is_a: MIRO:00000003 ! metabolic resistance [Term] id: MIRO:00000015 name: P450 monoxygenases resistance def: "Metabolic resistance due to quantitative or qualitative changes in P450 gene products (phase I metabolic enzymes capable of oxidizing endogenous and exogenous compounds by oxidation or other related reactions) resulting in more efficient insecticide detoxification, or reduced insecticide activation." [PMID:16925478 "Li et al. (2007), Ann Rev Entomol, 52: 231"] synonym: "P450 resistance" RELATED [] xref: PMID:16925478 "Li et al. (2007), Ann Rev Entomol, 52: 231" is_a: MIRO:00000003 ! metabolic resistance [Term] id: MIRO:00000016 name: COE qualitative change def: "A change of the COE activity; the resulting metabolic resistance is due to structural change of COE gene product resulting in more efficient metabolism or sequestration of insecticides." [KL:KL] synonym: "COE mutation" EXACT [] relationship: agent_in MIRO:00000012 ! carboxysterase resistance [Term] id: MIRO:00000021 name: resistance to single insecticide def: "A selected heritable characteristic in an insect population that results in the repeated failure of one single insecticide (but not others within or outside that class) to provide the intended level of control when used as recommended." [IRAC:manual "IRAC manual"] is_a: IDOMAL:0000349 ! insecticide resistance [Term] id: MIRO:00000028 name: stimulus independent resistance def: "Resistance resulting from a chemical-independent modification in behaviour that helps the insect avoid the lethal effect of insecticides." [IRAC:manual "IRAC manual"] xref: IRAC:manual "IRAC manual" is_a: MIRO:00000005 ! behavioural resistance [Term] id: MIRO:00000077 name: cuticle permeability related resistance def: "Change of permeability of the cuticle resulting in reduced insecticide uptake. This can lead to resistance due to lower amounts of insecticide inside the insect's body." [KL:KL] is_a: MIRO:00000021 ! resistance to single insecticide [Term] id: MIRO:00000078 name: enhanced excretion def: "Increased cuticle or cell-mediated insecticide excretion. This can lead to resistance due to lower amounts of insecticide inside the insect's body." [KL:KL] is_a: MIRO:00000077 ! cuticle permeability related resistance [Term] id: MIRO:00000079 name: COEa structural change of gene product in family def: "Structural change of COEa family gene product due to a mutation of the gene resulting in more efficient insecticide sequestration or metabolism." [KL:KL] is_a: MIRO:00000016 ! COE qualitative change [Term] id: MIRO:00000080 name: COEb structural change of gene product in family def: "Structural change of gene product in family COEb family gene product due to a mutation of the gene resulting in more efficient insecticide sequestration or metabolism." [KL:KL] is_a: MIRO:00000016 ! COE qualitative change [Term] id: MIRO:00000081 name: COEjh structural change of gene product in family def: "Structural change of gene product in family COEjh family gene product due to a mutation of the gene resulting in more efficient insecticide sequestration or metabolism." [KL:KL] is_a: MIRO:00000016 ! COE qualitative change [Term] id: MIRO:00000082 name: elevated COEa levels def: "Increased enzymatic activity due to a mutation that increases production of COEa gene products resulting in more efficient insecticide sequestration or metabolism." [KL:KL] is_a: MIRO:00000013 ! COE quantitative change [Term] id: MIRO:00000083 name: elevated COEb levels def: "Increased enzymatic activity due to a mutation that increases production of COEb gene products resulting in more efficient insecticide sequestration or metabolism." [KL:KL] is_a: MIRO:00000013 ! COE quantitative change [Term] id: MIRO:00000084 name: elevated COEjh level def: "Increased enzymatic activity due to a mutation that increases production of COEjh gene products resulting in more efficient insecticide sequestration or metabolism." [KL:KL] is_a: MIRO:00000013 ! COE quantitative change [Term] id: MIRO:00000085 name: GST quantitative change def: "Increased enzymatic activity due to a mutation that increases production of GST gene products resulting in more efficient insecticide detoxification." [KL:KL] synonym: "GSH S-transferase upregulation" EXACT [] relationship: agent_in MIRO:00000014 ! Glutathione S-transferase resistance [Term] id: MIRO:00000086 name: GST qualitative change def: "Structural changes in GST gene products resulting in more efficient insecticide detoxification." [KL:KL] synonym: "GSH S-tranferase mutation" EXACT [] relationship: agent_in MIRO:00000014 ! Glutathione S-transferase resistance [Term] id: MIRO:00000087 name: structural change of product in GSTd gene family def: "Structural changes in GSTd gene products resulting in more efficient insecticide detoxification." [KL:KL] is_a: MIRO:00000086 ! GST qualitative change [Term] id: MIRO:00000088 name: structural change of product in GSTe gene family def: "Structural changes in GSTe gene products resulting in more efficient insecticide detoxification." [KL:KL] is_a: MIRO:00000086 ! GST qualitative change [Term] id: MIRO:00000089 name: structural change of product in GSTo gene family def: "Structural changes in GSTo gene products resulting in more efficient insecticide detoxification." [KL:KL] is_a: MIRO:00000086 ! GST qualitative change [Term] id: MIRO:00000090 name: structural change of product in GSTt gene family def: "Structural changes in GSTt gene products resulting in more efficient insecticide detoxification." [KL:KL] is_a: MIRO:00000086 ! GST qualitative change [Term] id: MIRO:00000091 name: structural change of product in GSTu gene family def: "Structural changes in GSTu gene products resulting in more efficient insecticide detoxification." [KL:KL] is_a: MIRO:00000086 ! GST qualitative change [Term] id: MIRO:00000092 name: structural change of product in GSTz gene family def: "Structural changes in GST gene products resulting in more efficient insecticide detoxification." [KL:KL] is_a: MIRO:00000086 ! GST qualitative change [Term] id: MIRO:00000093 name: elevated GSTd level def: "Increased enzymatic activity due to a mutation that increases production of GSTd gene products resulting in more efficient insecticide detoxification." [KL:KL] is_a: MIRO:00000085 ! GST quantitative change [Term] id: MIRO:00000094 name: elevated GSTe level def: "Increased enzymatic activity due to a mutation that increases production of GSTe gene products resulting in more efficient insecticide detoxification." [KL:KL] is_a: MIRO:00000085 ! GST quantitative change [Term] id: MIRO:00000095 name: elevated GSTo level def: "Increased enzymatic activity due to a mutation that increases production of GSTo gene products resulting in more efficient insecticide detoxification." [KL:KL] is_a: MIRO:00000085 ! GST quantitative change [Term] id: MIRO:00000096 name: elevated GSTt level def: "Increased enzymatic activity due to a mutation that increases production of GSTt gene products resulting in more efficient insecticide detoxification." [KL:KL] is_a: MIRO:00000085 ! GST quantitative change [Term] id: MIRO:00000097 name: elevated GSTu level def: "Increased enzymatic activity due to a mutation that increases production of GSTu gene products resulting in more efficient insecticide detoxification." [KL:KL] is_a: MIRO:00000085 ! GST quantitative change [Term] id: MIRO:00000098 name: elevated GSTz level def: "Increased enzymatic activity due to a mutation that increases production of GSTz gene products resulting in more efficient insecticide detoxification." [KL:KL] is_a: MIRO:00000085 ! GST quantitative change [Term] id: MIRO:00000099 name: P450 qualitative change def: "Structural changes in P450 gene products resulting in more efficient insecticide sequestration or metabolism." [KL:KL] synonym: "P450 mutation" EXACT [] relationship: agent_in MIRO:00000015 ! P450 monoxygenases resistance [Term] id: MIRO:00000100 name: P450 quantitative change def: "Changed enzymatic activity due to a mutation that modifies production of P450 gene products resulting in more efficient insecticide detoxification." [KL:KL] synonym: "P450 upregulation" RELATED [] relationship: agent_in MIRO:00000015 ! P450 monoxygenases resistance [Term] id: MIRO:00000101 name: structural change of product in CYP3 gene family def: "Structural changes in CYP3 P450 gene products resulting in more efficient insecticide detoxification." [KL:KL] is_a: MIRO:00000099 ! P450 qualitative change [Term] id: MIRO:00000102 name: structural change of product in CYP4 gene family def: "Structural changes in CYP4 P450 gene products resulting in more efficient insecticide detoxification." [KL:KL] is_a: MIRO:00000099 ! P450 qualitative change [Term] id: MIRO:00000103 name: structural change of product in CYP6 gene family def: "Structural changes in CYP6 P450 gene products resulting in more efficient insecticide detoxification." [KL:KL] is_a: MIRO:00000099 ! P450 qualitative change [Term] id: MIRO:00000104 name: structural change of product in CYP9 gene family def: "Structural changes in CYP9 P450 gene products resulting in more efficient insecticide detoxification." [KL:KL] is_a: MIRO:00000099 ! P450 qualitative change [Term] id: MIRO:00000105 name: structural change of product in CYP12 gene family def: "Structural changes in CYP12 P450 gene products resulting in more efficient insecticide detoxification." [KL:KL] is_a: MIRO:00000099 ! P450 qualitative change [Term] id: MIRO:00000106 name: structural change of product in CYP15 gene family def: "Structural changes in CYP15 P450 gene products resulting in more efficient insecticide detoxification." [KL:KL] is_a: MIRO:00000099 ! P450 qualitative change [Term] id: MIRO:00000107 name: differential CYP12 level def: "Modified enzymatic activity due to a mutation that modifies production of CYP12 P450 gene products." [KL:KL] is_a: MIRO:00000100 ! P450 quantitative change [Term] id: MIRO:00000108 name: differential CYP15 level def: "Modified enzymatic activity due to a mutation that modifies production of CYP15 P450 gene products." [KL:KL] is_a: MIRO:00000100 ! P450 quantitative change [Term] id: MIRO:00000109 name: differential CYP3 level def: "Modified enzymatic activity due to a mutation that modifies production of CYP3 P450 gene products." [KL:KL] is_a: MIRO:00000100 ! P450 quantitative change [Term] id: MIRO:00000110 name: differential CYP4 level def: "Modified enzymatic activity due to a mutation that modifies production of CYP4 P450 gene products." [KL:KL] is_a: MIRO:00000100 ! P450 quantitative change [Term] id: MIRO:00000111 name: differential CYP6 level def: "Modified enzymatic activity due to a mutation that modifies production of CYP6 P450 gene products." [KL:KL] is_a: MIRO:00000100 ! P450 quantitative change [Term] id: MIRO:00000112 name: differential CYP9 level def: "Modified enzymatic activity due to a mutation that modifies production of CYP9 P450 gene products." [KL:KL] is_a: MIRO:00000100 ! P450 quantitative change [Term] id: MIRO:00000113 name: modified sodium channel def: "Structural changes of the insecticide target sodium channel gene product, which decreases its response to the insecticide." [KL:KL] relationship: agent_in MIRO:00000131 ! sodium channel mediated resistance [Term] id: MIRO:00000114 name: modified AChE def: "Structural changes of the insecticide target acetylcholinesterase gene product, which decreases its response to the insecticide." [KL:KL] relationship: agent_in MIRO:00000127 ! AChE mediated resistance [Term] id: MIRO:00000115 name: modified GABA receptor def: "Structural changes of the insecticide target GABA receptor gene product, which decreases its response to the insecticide." [KL:KL] relationship: agent_in MIRO:00000128 ! GABA receptor mediated resistance [Term] id: MIRO:00000116 name: modified midgut receptor def: "Structurally modified protein in the insects' midgut that is no longer able to bind an insecticide." [KL:KL] relationship: agent_in MIRO:00000129 ! midgut receptor mediated resistance [Term] id: MIRO:00000117 name: modified nicotinic receptor def: "Structural change of the insecticide target nAChR gene product resulting in decreased response to the insecticide." [KL:KL] relationship: agent_in MIRO:00000130 ! nicotinic receptor mediated resistance [Term] id: MIRO:00000118 name: modified midgut protease activity def: "Modified protease activity caused by a mutation, resulting in differential processing of bacterial pro-insecticides and, thus, reduced toxicity." [KL:KL] relationship: agent_in MIRO:00000003 ! metabolic resistance [Term] id: MIRO:00000119 name: elevated AChE levels def: "Increased enzymatic activity due to a mutation that increases production of AChE gene products." [KL:KL] relationship: agent_in MIRO:00000127 ! AChE mediated resistance [Term] id: MIRO:00000120 name: AChE1 G119S def: "Resistance-associated point mutation of amino acid at position 119 in the insecticide target acetylcholinesterase 1 gene product; this structural change leads to decreased response to the insecticide." [PMID:15242706 "Hemingway et al. (2004) Ins. Biochem. Mol. Biol. 34(7):653-665"] is_a: MIRO:00000114 ! modified AChE [Term] id: MIRO:00000121 name: AChE1 F331W def: "Resistance-associated point mutation of amino acid at position 331 in the insecticide target acetylcholinesterase 1 gene product; this structural change leads to decreased response to the insecticide." [PMID:15242706 "Hemingway et al. (2004) Ins. Biochem. Mol. Biol. 34(7):653-665"] is_a: MIRO:00000114 ! modified AChE [Term] id: MIRO:00000122 name: AChE1 F290V def: "Resistance-associated point mutation of amino acid at position 290 in the insecticide target acetylcholinesterase 1 gene product; this structural change leads to decreased response to the insecticide." [PMID:15242706 "Hemingway et al. (2004) Ins. Biochem. Mol. Biol. 34(7):653-665"] is_a: MIRO:00000114 ! modified AChE [Term] id: MIRO:00000123 name: Rdl A296G def: "Resistance-associated point mutation of amino acid at position 296 in the insecticide target GABA receptor gene product causing a structural change and decreased response to the insecticide." [PMID:15242706 "Hemingway et al. (2004) Ins. Biochem. Mol. Biol. 34(7):653-665"] is_a: MIRO:00000115 ! modified GABA receptor [Term] id: MIRO:00000124 name: modified Cry def: "Structural change in the insecticide target Cry gene products resulting in decreased response to insecticides." [KL:KL] is_a: MIRO:00000116 ! modified midgut receptor [Term] id: MIRO:00000125 name: Kdr L1014S def: "Resistance-associated point mutation of amino acid at position 1014 (L-S) in the insecticide target sodium channel gene product causing a structural change and decreased response to the insecticide." [PMID:15242706 "Hemingway et al. (2004) Ins. Biochem. Mol. Biol. 34(7):653-665"] is_a: MIRO:00000113 ! modified sodium channel [Term] id: MIRO:00000126 name: Kdr L1014F def: "Resistance-associated point mutation of amino acid at position 1014 (L-S) in the insecticide target sodium channel gene product causing a structural change and decreased response to the insecticide." [PMID:15242706 "Hemingway et al. (2004) Ins. Biochem. Mol. Biol. 34(7):653-665"] is_a: MIRO:00000113 ! modified sodium channel [Term] id: MIRO:00000127 name: AChE mediated resistance def: "Resistance due to mutation leading to structural or quantitative changes of the insecticide target acetylcholinesterase gene product." [KL:KL] is_a: MIRO:00000004 ! target-site resistance [Term] id: MIRO:00000128 name: GABA receptor mediated resistance def: "Resistance due to mutation leading to structural or quantitative changes of the insecticide target GABA receptor gene product." [KL:KL] is_a: MIRO:00000004 ! target-site resistance [Term] id: MIRO:00000129 name: midgut receptor mediated resistance def: "Target-site resistance due to the fact that the receptors in the insects' midgut that are responsible for binding an insecticide can no longer function properly due to a mutation in the corresponding gene." [KL:KL] is_a: MIRO:00000004 ! target-site resistance [Term] id: MIRO:00000130 name: nicotinic receptor mediated resistance def: "Resistance due to mutation leading to structural or quantitative changes of the insecticide target nAChR gene product, resulting in decreased response to the insecticide." [KL:KL] is_a: MIRO:00000004 ! target-site resistance [Term] id: MIRO:00000131 name: sodium channel mediated resistance def: "Resistance due to mutation leading to structural changes of the insecticide target sodium channel gene product." [KL:KL] is_a: MIRO:00000004 ! target-site resistance [Term] id: MIRO:10000001 name: chitin biosynthesis inhibitor def: "A chemical substance which inhibits chitin biosynthesis." [PT:PT] xref: IRAC:eClassification "http://www.irac-online.org/eClassification/" is_a: IDOMAL:0000001 ! role [Term] id: MIRO:10000002 name: carbamate def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:38462 ! acetylcholine esterase inhibitor [Term] id: MIRO:10000030 name: growth inhibitor def: "A chemical substance which inhibits growth." [PT:PT] xref: IRAC:eClassification "http://www.irac-online.org/eClassification/" is_a: IDOMAL:0000001 ! role [Term] id: MIRO:10000086 name: prothiofos def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:25708 ! organophosphate [Term] id: MIRO:10000100 name: GABA-gated chloride channel antagonist def: "A chemical substance which acts as GABA-gated chloride channel antagonist." [PT:PT] xref: IRAC:eClassification "http://www.irac-online.org/eClassification/" is_a: IDOMAL:0000001 ! role [Term] id: MIRO:10000101 name: moulting disruptor def: "A chemical substance which is being used as insecticide." [PT:PT] xref: IRAC:eClassification "http://www.irac-online.org/eClassification/" is_a: MIRO:10000030 ! growth inhibitor is_a: MIRO:10000169 ! active insecticidal substance [Term] id: MIRO:10000108 name: chlorphoxim def: "A chemical substance which is being used as insecticide." [PT:PT] synonym: "chlorphoxin" EXACT [] xref: CAS:7-(2-chlorophenyl)-4-ethoxy-3\,5-dioxa-6-aza-4-phosphaoct-6-ene-8-nitrile4-sulfide xref: IUPAC:O\,O-diethyl2-chloro--cyanobenzylideneaminooxyphosphonothioate is_a: CHEBI:25708 ! organophosphate [Term] id: MIRO:10000109 name: fipronil / phenylpyrazole def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000100 ! GABA-gated chloride channel antagonist [Term] id: MIRO:10000159 name: nicotinic acetylcholine receptor agontist/antagonist def: "A chemical substance which acts as nicotinic acetylcholine receptor agonist/antagonist." [PT:PT] xref: IRAC:eClassification "http://www.irac-online.org/eClassification/" is_a: IDOMAL:0000001 ! role [Term] id: MIRO:10000169 name: active insecticidal substance def: "The ingredient which is pharmaceutically active in a pesticide formulation." [PT:PT] is_a: IDOMAL:0000930 ! insecticidal substance [Term] id: MIRO:10000171 name: glycosaminoglycan def: "Glycosaminoglycans are long unbranched polysaccharides consisting of a repeating disaccharide unit." [Wikipedia:Glycosaminoglycan] synonym: "GAG" NARROW [] synonym: "mucopolysaccharides" NARROW [] is_a: IDOMAL:0000672 ! chemical compound created_by: louis creation_date: 2009-06-11T03:58:55Z [Term] id: MIRO:10000174 name: allosteric agonist of nicotinic acetylcholine receptor def: "A chemical substance which acts as allosteric agonist of nicotinic acetylcholine receptor." [PT:PT] xref: IRAC:eClassification "http://www.irac-online.org/eClassification/" is_a: IDOMAL:0000001 ! role [Term] id: MIRO:10000176 name: chloride channel activator def: "A chemical substance which activates chloride channels." [PT:PT] xref: IRAC:eClassification "http://www.irac-online.org/eClassification/" is_a: IDOMAL:0000001 ! role [Term] id: MIRO:10000183 name: juvenile hormone analogue def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role CHEBI:24942 ! juvenile hormone mimic [Term] id: MIRO:10000194 name: methyl bromide and other alkyl halides def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:39275 ! methyl bromide [Term] id: MIRO:10000206 name: growth inhibitor sensu acarea def: "A chemical substance which is being used as insecticide." [PT:PT] xref: IRAC:eClassification "http://www.irac-online.org/eClassification/" is_a: MIRO:10000030 ! growth inhibitor [Term] id: MIRO:10000209 name: malaoxon def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:6651 ! malathion [Term] id: MIRO:10000211 name: chlorthion def: "A chemical substance which is being used as insecticide." [PT:PT] synonym: "chlorothion" EXACT [] is_a: CHEBI:25708 ! organophosphate [Term] id: MIRO:10000213 name: insect midgut membranes disruptor def: "A chemical substance which disrupts insect midgut membranes." [PT:PT] xref: IRAC:eClassification "http://www.irac-online.org/eClassification/" is_a: IDOMAL:0000001 ! role [Term] id: MIRO:10000214 name: Bacillus thurigiensis toxin def: "A chemical substance which is being used as insecticide." [PT:PT] synonym: "Bt toxin" EXACT [] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000213 ! insect midgut membranes disruptor created_by: Pantelis creation_date: 2009-03-13T10:56:22Z [Term] id: MIRO:10000215 name: Bacillus thurigiensis var. israelensis toxin def: "A chemical substance which is being used as insecticide." [PT:PT] synonym: "Bti" EXACT [] is_a: MIRO:10000214 ! Bacillus thurigiensis toxin [Term] id: MIRO:10000217 name: Bacillus thurigiensis var. sphaericus toxin def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000214 ! Bacillus thurigiensis toxin [Term] id: MIRO:10000219 name: Bacillus thurigiensis var. aizawai toxin def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000214 ! Bacillus thurigiensis toxin [Term] id: MIRO:10000221 name: Bacillus thurigiensis var. kurstaki toxin def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000214 ! Bacillus thurigiensis toxin [Term] id: MIRO:10000223 name: Bacillus thurigiensis var. tenebrionensis toxin def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000214 ! Bacillus thurigiensis toxin [Term] id: MIRO:10000224 name: oxidative phosphorylation inhibitor def: "A chemical substance which inhibits oxidative phosphorylation." [PT:PT] synonym: "disruption of ATP formation" EXACT [] xref: IRAC:eClassification "http://www.irac-online.org/eClassification/" is_a: IDOMAL:0000001 ! role [Term] id: MIRO:10000236 name: uncoupler of oxidative phosphorylation def: "A chemical substance which uncouples oxidative phosphorylation via disruption of proton gradient." [PT:PT] xref: IRAC:eClassification "http://www.irac-online.org/eClassification/" is_a: IDOMAL:0000001 ! role [Term] id: MIRO:10000255 name: moulting disruptor in Diptera def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: MIRO:10000101 ! moulting disruptor [Term] id: MIRO:10000265 name: octopaminergic agonist def: "A chemical substance which acts as octopaminergic agonist." [PT:PT] xref: IRAC:eClassification "http://www.irac-online.org/eClassification/" is_a: IDOMAL:0000001 ! role [Term] id: MIRO:10000274 name: mitochondrial complex I electron transport inhibitor def: "A chemical substance which inhibits mitochondrial complex I electron transport chain." [PT:PT] xref: IRAC:eClassification "http://www.irac-online.org/eClassification/" is_a: IDOMAL:0000001 ! role [Term] id: MIRO:10000284 name: lipid synthesis inhibitor def: "A chemical substance which inhibits lipid synthesis." [PT:PT] xref: IRAC:eClassification "http://www.irac-online.org/eClassification/" is_a: IDOMAL:0000001 ! role [Term] id: MIRO:10000289 name: spirotetramat def: "A chemical substance which is being used as insecticide." [PT:PT] is_a: CHEBI:33755 ! tetronic acid derivative [Term] id: MIRO:10000295 name: neuronal inhibitor def: "A chemical substance which is being used as insecticide." [PT:PT] xref: IRAC:eClassification "http://www.irac-online.org/eClassification/" is_a: IDOMAL:0000001 ! role [Term] id: MIRO:10000296 name: bifenazate def: "A chemical substance which is able to kill insects." [PT:PT] is_a: MIRO:10000169 ! active insecticidal substance relationship: has_role MIRO:10000295 ! neuronal inhibitor [Term] id: MIRO:10000297 name: aconitase inhibitor def: "A chemical substance which inhibits aconitase." [PT:PT] xref: IRAC:eClassification "http://www.irac-online.org/eClassification/" is_a: IDOMAL:0000001 ! role [Term] id: MIRO:40000000 name: genus Bironella def: "A genus of Anophelinae." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: IDOMAL:0000600 ! anophelinae [Term] id: MIRO:40000001 name: Bironella def: "A subgenus of genus Bironella." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000000 ! genus Bironella [Term] id: MIRO:40000002 name: Bironella gracilis def: "A species of subgenus Bironella." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Bironella occulta" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Bironella walchi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000001 ! Bironella [Term] id: MIRO:40000003 name: Bironella simmondsi def: "A species of subgenus Bironella." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000001 ! Bironella [Term] id: MIRO:40000004 name: Brugella def: "A subgenus of genus Bironella." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000000 ! genus Bironella [Term] id: MIRO:40000005 name: Bironella hollandi def: "A species of subgenus Brugella." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000004 ! Brugella [Term] id: MIRO:40000015 name: genus Anopheles def: "A genus of Anophelinae." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: IDOMAL:0000600 ! anophelinae [Term] id: MIRO:40000016 name: Anopheles def: "A subgenus of genus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000015 ! genus Anopheles [Term] id: MIRO:40000017 name: Anopheles aberrans def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000018 name: Anopheles acaci def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000019 name: Anopheles ahomi def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000020 name: Anopheles aitkenii def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles pallida" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000021 name: Anopheles albotaeniatus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000022 name: Anopheles algeriensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles lukisii" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000023 name: Anopheles alongensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles tonkinensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000024 name: Anopheles anchietai def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000025 name: Anopheles annandalei def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles djajasanensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000026 name: Anopheles annulipalpis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000027 name: Anopheles apicimacula def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000028 name: Anopheles arboricola def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000029 name: Anopheles argyropus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000030 name: Anopheles asiaticus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000031 name: Anopheles atratipes def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000032 name: Anopheles atroparvus def: "A species of subgenus Anopheles, which acts as a major North Eurasian & Mediterranean malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles cambournaci" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles fallax" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40000033 name: Anopheles atropos def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles ferruginosus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000034 name: Anopheles aztecus def: "A species of subgenus Anopheles, which acts as a minor Central American malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40000035 name: Anopheles baezai def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000036 name: Anopheles baileyi def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000037 name: Anopheles balerensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000038 name: Anopheles bancroftii def: "A species of subgenus Anopheles, which acts as a minor Australasian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40000039 name: Anopheles barbiventris var. def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000040 name: Anopheles barberi def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles niger" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000041 name: Anopheles barbirostris def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles innominata" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles martini" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000042 name: Anopheles barbumbrosus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles pallidus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles pseudumbrosus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000043 name: Anopheles barianensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000044 name: Anopheles beklemishevi def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000045 name: Anopheles bengalensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000046 name: Anopheles borneensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000047 name: Anopheles bradleyi def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000048 name: Anopheles brevipalpis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000049 name: Anopheles brevirostris def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000050 name: Anopheles bulkleyi def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000051 name: Anopheles bustamentei def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000052 name: Anopheles calderoni def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000053 name: Anopheles caliginosus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000054 name: Anopheles campestris def: "A species of subgenus Anopheles, which acts as a minor Malaysian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40000055 name: Anopheles changfus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000056 name: Anopheles chiriquiensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000057 name: Anopheles chodukini def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000058 name: Anopheles claviger def: "A species of subgenus Anopheles, which acts as a minor Mediterranean malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles amaurus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles grisescens" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles habib" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles missiroli" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles pollutus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles turkestani" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles villosus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40000059 name: Anopheles colledgei def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000060 name: Anopheles collessi def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000061 name: Anopheles concolor def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000062 name: Anopheles corethroides def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000063 name: Anopheles costai def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles bonneorum" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000064 name: Anopheles coustani def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles mauritianus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles similis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000065 name: Anopheles crawfordi def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000070 name: Nyssorhynchus def: "A subgenus of genus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000015 ! genus Anopheles [Term] id: MIRO:40000071 name: Anopheles albimanus def: "A species of subgenus Nyssorhynchus, which acts as a major American malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles albipes" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles bisignatus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles cubensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles gorgasi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles tarsimaculata" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles trisignatus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40000072 name: Anopheles crucians def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000073 name: Anopheles crypticus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles coustani" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000074 name: Anopheles cucphuongensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000075 name: Anopheles culiciformis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles culiciformis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000076 name: Anopheles dazhaius def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000077 name: Anopheles diluvialis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000078 name: Anopheles donaldi def: "A species of subgenus Anopheles, which acts as a minor Malaysian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40000079 name: Anopheles earlei def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000080 name: Anopheles eiseni def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles geometricus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles niveopalpis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles Variety:" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000081 name: Anopheles geometricus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000082 name: Anopheles ejercitoi def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000083 name: Anopheles engarensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000084 name: Anopheles evandroi def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000085 name: Anopheles fausti def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000086 name: Anopheles fluminensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles holmbergi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000087 name: Anopheles forattinii def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000088 name: Anopheles fragilis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles stantoni" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles treacherii" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000089 name: Anopheles franciscanus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles boydi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles willardi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000090 name: Anopheles freeborni def: "A species of subgenus Anopheles, which acts as a major North American malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40000091 name: Anopheles freyi def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000092 name: Anopheles fuscicolor def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000093 name: Anopheles gabaldoni def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000094 name: Anopheles georgianus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000095 name: Anopheles gigas def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000096 name: Anopheles formosus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000097 name: Anopheles simlensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000098 name: Anopheles refutans def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000099 name: Anopheles sumatrana def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000100 name: Anopheles danaubento def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000101 name: Anopheles oedjalikalah def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000102 name: Anopheles pantjarbatu def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000103 name: Anopheles crockeri def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000104 name: Anopheles grabhamii def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000105 name: Anopheles guarao def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000106 name: Anopheles hectoris def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles cricillium" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000107 name: Anopheles heiheensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000108 name: Anopheles hermsi def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000109 name: Anopheles hunteri def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000110 name: Anopheles hyrcanus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles lerowi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles mahmuti" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles marzinovski" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles mesopotamiae" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles pictus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles popovi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000111 name: Anopheles implexus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles henrardi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000112 name: Anopheles insulaeflorum def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000113 name: Anopheles intermedius def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000114 name: Anopheles inundatus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000115 name: Anopheles judithae def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000116 name: Anopheles junlianensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000117 name: Anopheles kiangsuensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000118 name: Anopheles kweiyangensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000119 name: Anopheles kyondawensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000120 name: Anopheles labranchiae def: "A species of subgenus Anopheles, which acts as a major Mediterranean malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles pergusae" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles sicaulti" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40000121 name: Anopheles lesteri def: "A species of subgenus Anopheles, which acts as a major Chinese malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles anthropophagus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40000122 name: Anopheles letifer def: "A species of subgenus Anopheles, which acts as a minor Malaysian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40000123 name: Anopheles liangshanensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles kunmingensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000124 name: Anopheles lindesayi def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles benguetensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles cameronensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles japonicus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles maculata" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles pleccau" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles Subspecies:" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000125 name: Anopheles pleccau def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000126 name: Anopheles cameronensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000127 name: Anopheles japonicus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000128 name: Anopheles benguetensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000129 name: Anopheles maculipennis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles alexandraeschingarevi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles basilii" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles typicus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000130 name: Anopheles maculipes def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000131 name: Anopheles malefactor def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000132 name: Anopheles marteri def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles conquensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles sogdianus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000133 name: Anopheles martinius def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles elutior" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles relictus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000134 name: Anopheles mattogrossensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles amazonicus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000135 name: Anopheles maverlius def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000136 name: Anopheles mediopunctatus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles costalimai" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles limai" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles rockefelleri" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000137 name: Anopheles melanoon def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles subalpinus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000138 name: Anopheles mengalangensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000139 name: Anopheles messeae def: "A species of subgenus Anopheles, which acts as a minor North Eurasian & Mediterranean malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40000140 name: Anopheles minor def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000141 name: Anopheles montanus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000142 name: Anopheles namibiensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000143 name: Anopheles neomaculipalpus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000144 name: Anopheles papuensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000145 name: Anopheles paraliae def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000146 name: Anopheles guatemalensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000147 name: Anopheles neghmei def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40000148 name: Anopheles anomalophyllus def: "A species of subgenus Nyssorhynchus." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus [Term] id: MIRO:40000149 name: Anopheles antunesi def: "A species of subgenus Nyssorhynchus." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus [Term] id: MIRO:40000150 name: Anopheles aquasalis def: "A species of subgenus Nyssorhynchus, which acts as a major Central & South American malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles delta" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles deltaorinoquensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles emilianus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles guarauno" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles guarujaensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40000151 name: Anopheles albitarsis def: "A species of subgenus Nyssorhynchus, which acts as a minor Central & South American malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles imperfectus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles limai" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40000152 name: Anopheles argyritarsis def: "A species of subgenus Nyssorhynchus, which acts as a major Central & South American malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles rooti" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40000153 name: Anopheles benarrochi def: "A species of subgenus Nyssorhynchus." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus [Term] id: MIRO:40000154 name: Anopheles braziliensis def: "A species of subgenus Nyssorhynchus, which acts as a minor South American malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles pessoai" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40000155 name: Anopheles darlingi def: "A species of subgenus Nyssorhynchus, which acts as a major Central & South American malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles paulistensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40000156 name: Anopheles deaneorum def: "A species of subgenus Nyssorhynchus." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus [Term] id: MIRO:40000157 name: Anopheles dunhami def: "A species of subgenus Nyssorhynchus." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus [Term] id: MIRO:40000158 name: Anopheles evansae def: "A species of subgenus Nyssorhynchus." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles ayrozai" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles clarki" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles Metcalfi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles noroestensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus [Term] id: MIRO:40000159 name: Anopheles galvaoi def: "A species of subgenus Nyssorhynchus." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus [Term] id: MIRO:40000160 name: Anopheles ininii def: "A species of subgenus Nyssorhynchus." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus [Term] id: MIRO:40000161 name: Anopheles lanei def: "A species of subgenus Nyssorhynchus." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus [Term] id: MIRO:40000162 name: Anopheles lutzii def: "A species of subgenus Nyssorhynchus." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles guarani" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles nigra" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus [Term] id: MIRO:40000163 name: Anopheles marajoara def: "A species of subgenus Nyssorhynchus." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles domesticus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus [Term] id: MIRO:40000164 name: Anopheles nigritarsis def: "A species of subgenus Nyssorhynchus." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus [Term] id: MIRO:40000165 name: Anopheles nuneztovari def: "A species of subgenus Nyssorhynchus, which acts as a minor South American malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles goeldii" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40000166 name: Anopheles oswaldoi def: "A species of subgenus Nyssorhynchus." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles aquacaelestis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus [Term] id: MIRO:40000167 name: Anopheles konderi def: "A species of subgenus Nyssorhynchus." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus [Term] id: MIRO:40000168 name: Anopheles parvus def: "A species of subgenus Nyssorhynchus." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus [Term] id: MIRO:40000169 name: Anopheles pictipennis def: "A species of subgenus Nyssorhynchus." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles bigotii" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles chilensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles variegatus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus [Term] id: MIRO:40000170 name: Anopheles rangeli def: "A species of subgenus Nyssorhynchus." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus [Term] id: MIRO:40000171 name: Anopheles rondoni def: "A species of subgenus Nyssorhynchus." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus [Term] id: MIRO:40000172 name: Anopheles sanctielii def: "A species of subgenus Nyssorhynchus." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus [Term] id: MIRO:40000173 name: Anopheles sawyeri def: "A species of subgenus Nyssorhynchus." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus [Term] id: MIRO:40000174 name: Anopheles strodei def: "A species of subgenus Nyssorhynchus." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles albertoi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles arthuri" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles artigasi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles lloydi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles ramosi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus [Term] id: MIRO:40000175 name: Anopheles triannulatus def: "A species of subgenus Nyssorhynchus, which acts as a minor South American malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles bachmanni" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles chagasi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles cuyabensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles davisi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles perezi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40000176 name: Anopheles trinkae def: "A species of subgenus Nyssorhynchus." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus [Term] id: MIRO:40000177 name: Stethomyia def: "A subgenus of genus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000015 ! genus Anopheles [Term] id: MIRO:40000178 name: Anopheles acanthotorynus def: "A species of subgenus Stethomyia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000177 ! Stethomyia [Term] id: MIRO:40000179 name: Anopheles canorii def: "A species of subgenus Stethomyia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000177 ! Stethomyia [Term] id: MIRO:40000180 name: Anopheles kompi def: "A species of subgenus Stethomyia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000177 ! Stethomyia [Term] id: MIRO:40000181 name: Anopheles nimbus def: "A species of subgenus Stethomyia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles lineata" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000177 ! Stethomyia [Term] id: MIRO:40000182 name: Anopheles thomasi def: "A species of subgenus Stethomyia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles lewisi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000177 ! Stethomyia [Term] id: MIRO:40000193 name: Bironella obscura def: "A species of subgenus Brugella." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000004 ! Brugella [Term] id: MIRO:40000194 name: Bironella travestita def: "A species of subgenus Brugella." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000004 ! Brugella [Term] id: MIRO:40000195 name: Neobironella def: "A subgenus of genus Bironella." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000000 ! genus Bironella [Term] id: MIRO:40000196 name: Bironella confusa def: "A species of subgenus Neobironella." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000195 ! Neobironella [Term] id: MIRO:40000197 name: BIronella derooki def: "A species of subgenus Neobironella." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Bironella soesiloi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000195 ! Neobironella [Term] id: MIRO:40000198 name: Bironella papuae def: "A species of subgenus Neobironella." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Bironella brugi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000195 ! Neobironella [Term] id: MIRO:40000803 name: Anopheles gambiae chromosomal form def: "A form of Anopheles gambiae sensu stricto differentiated by defined chromosomal rearrengements." [PMID:10645562 "Parassitologia. 1998 Dec;40(4):477-511."] is_a: MIRO:40003829 ! Anopheles gambiae [Term] id: MIRO:40002217 name: Cellia def: "A subgenus of genus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000015 ! genus Anopheles [Term] id: MIRO:40002218 name: Anopheles aconitus def: "A species of subgenus Cellia, which acts as a major Malaysian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles albirostris" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles brahmacharii" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40002219 name: Anopheles amictus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002220 name: Anopheles annularis def: "A species of subgenus Cellia, which acts as a major Malaysian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles adiei" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles fuliginosus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles jamesii" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles leucopus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles lineata" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles nagpori" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40002221 name: Anopheles annulatus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002222 name: Anopheles annulipes def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles derricki" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles mastersi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles musivus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles perplerus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles persimilis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002223 name: Anopheles apoci def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002224 name: Anopheles arabiensis def: "A member species of the species complex Anopheles gambiae sensu lato, which acts as a major Afrotropical malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles davidsoni" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003480 ! Anopheles gambiae sensu lato relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40002225 name: Anopheles ardensis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles pyretophoroides" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002226 name: Anopheles argenteolobatus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles pseudosquomosa" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002227 name: Anopheles aruni def: "A member species of the species complex Anopheles funestus sensu lato." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003478 ! Anopheles funestus sensu lato [Term] id: MIRO:40002228 name: Anopheles aurirostris def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002229 name: Anopheles austenii def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002230 name: Anopheles azaniae def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002231 name: Anopheles azevedoi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles deaconi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002232 name: Anopheles baisasi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002233 name: Anopheles balabacensis def: "A species of subgenus Cellia, which acts as a major Malaysian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40002234 name: Anopheles barberellus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002235 name: Anopheles berghei def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002236 name: Anopheles brohieri def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles gilroyi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles masseguini" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles septentrionalis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002237 name: Anopheles brucei def: "A member species of the species complex Anopheles funestus sensu lato." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003478 ! Anopheles funestus sensu lato [Term] id: MIRO:40002238 name: Anopheles brumpti def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002239 name: Anopheles brunnipes def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002240 name: Anopheles buxtoni def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002241 name: Anopheles bwambae def: "A member species of the species complex Anopheles gambiae sensu lato." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003480 ! Anopheles gambiae sensu lato [Term] id: MIRO:40002242 name: Anopheles cameroni def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002243 name: Anopheles carnevalei def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002244 name: Anopheles caroni def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002245 name: Anopheles carteri def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002246 name: Anopheles christyi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002247 name: Anopheles cinctus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002248 name: Anopheles cinereus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles hispaniola" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles italicus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles jehafi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles myzomyifacies" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles rifenus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles Subspecies:" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002249 name: Anopheles hispaniola def: "A species of subgenus Cellia, which acts as a minor Mediterranean & Afro-Arabian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40002250 name: Anopheles clowi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002251 name: Anopheles comorensis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002252 name: Anopheles confusus def: "A member species of the species complex Anopheles funestus sensu lato." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003478 ! Anopheles funestus sensu lato [Term] id: MIRO:40002253 name: Anopheles cristatus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002254 name: Anopheles cristipalpis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002255 name: Anopheles culicifacies def: "A species of subgenus Cellia, which acts as a major Indo-Iranian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles adenensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles indica" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles listoni" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles punjobensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40002256 name: Anopheles cydippis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles entebbiensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002257 name: Anopheles dancalicus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002258 name: Anopheles daudi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002259 name: Anopheles deemingi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002260 name: genus Chagasia def: "A genus of Anophelinae." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: IDOMAL:0000600 ! anophelinae [Term] id: MIRO:40002261 name: Chagasia bathana def: "A species of genus Chagasia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002260 ! genus Chagasia [Term] id: MIRO:40002262 name: Anopheles demeilloni def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002263 name: Anopheles dirus def: "A species of subgenus Cellia, which acts as a major Malaysian & Indo-Chinese malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40002264 name: Anopheles dispar def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002265 name: Anopheles distinctus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles melanocosta" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002266 name: Anopheles domicola def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles gingeroi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002267 name: Chagasia bonneae def: "A species of genus Chagasia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002260 ! genus Chagasia [Term] id: MIRO:40002268 name: Anopheles dravidicus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002269 name: Anopheles dthali def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles wardi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002270 name: Anopheles dualaensis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002271 name: Anopheles dureni def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002272 name: Anopheles elegans def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002273 name: Anopheles erepens def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002274 name: Chagasia fajardi def: "A species of genus Chagasia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Chagasia maculata" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Chagasia neivae" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Chagasia stigmopteryr" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002260 ! genus Chagasia [Term] id: MIRO:40002275 name: Anopheles erythraeus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002276 name: Anopheles ethiopicus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002277 name: Anopheles faini def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles vanthieli" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002278 name: Anopheles farauti def: "A species of subgenus Cellia, which acts as a major Australasian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles moluccensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40002279 name: Chagasia rozeboomi def: "A species of genus Chagasia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002260 ! genus Chagasia [Term] id: MIRO:40002280 name: Anopheles filipinae def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002281 name: Anopheles flavicosta def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40002282 name: Anopheles flavirostris def: "A species of subgenus Cellia, which acts as a major Malaysian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles (cohesia)" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles merak" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003065 name: Anopheles gambiae molecular form def: "A form of Anopheles gambiae sensu stricto differentiated by defined DNA polymorphisms." [PMID:11240632 "Insect Mol Biol. 2001 Feb;10(1):9-18."] is_a: MIRO:40003829 ! Anopheles gambiae [Term] id: MIRO:40003235 name: Anopheles gambiae molecular form M def: "A molecular form of Anopheles gambiae sensu stricto, defined by the presence of a given haplotype of the rDNA intergenic spacer." [PMID:11240632 "Insect Mol Biol. 2001 Feb;10(1):9-18."] synonym: "M form" EXACT [] is_a: MIRO:40003065 ! Anopheles gambiae molecular form [Term] id: MIRO:40003398 name: Anopheles franciscoi def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003399 name: Anopheles hodgkini def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003400 name: Anopheles interruptus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003401 name: Anopheles koreicus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles edwardsi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles hisaoe" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles punctibasis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003402 name: Anopheles lewisi def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles selengensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003403 name: Anopheles manalangi def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003404 name: Anopheles nigerrimus def: "A species of subgenus Anopheles, which acts as a minor Indo-Chinese & Malaysian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles bentleyi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles indiensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles minutus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles venhuisi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles williamsoni" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003405 name: Anopheles nilgiricus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003406 name: Anopheles nitidus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003407 name: Anopheles noniae def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003408 name: Anopheles obscurus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles nowlini" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles strachanii" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003409 name: Anopheles occidentalis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003410 name: Anopheles okuensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003411 name: Anopheles omorii def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003412 name: Anopheles palmatus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003413 name: Anopheles paludis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003414 name: Anopheles parapunctipennis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003415 name: Anopheles peditaeniatus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003416 name: Anopheles perplexens def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003417 name: Anopheles peryassui def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles alagoanii" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles celidopus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles lutzi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003418 name: Anopheles petragnani def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles portucaliensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003419 name: Anopheles peytoni def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003420 name: Anopheles pilinotum def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003421 name: Anopheles pinjaurensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003422 name: Anopheles plumbeus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles corsicanus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles intermedius" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles nigripes" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003423 name: Anopheles pollicaris def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003424 name: Anopheles powderi def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003425 name: Anopheles powelli def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003426 name: Anopheles pseudobarbirostris def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003427 name: Anopheles pseudomaculipes def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003428 name: Anopheles pseudopictus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003429 name: Anopheles pseudopunctipennis def: "A species of subgenus Anopheles, which acts as a major Central & South American malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles argentinus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles bifoliata" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles levicastilloi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles neghmei" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles noei" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles patersoni" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles peruvianus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles rivadeneirai" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles Subspecies:" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles tucumanus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles Variety:" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003430 name: Anopheles levicastilloi def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003431 name: Anopheles rivadeneirai def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003432 name: Anopheles patersoni def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003433 name: Anopheles bifoliata def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003434 name: Anopheles noei def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003435 name: Anopheles pseudosinensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003436 name: Anopheles pseudostigmaticus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003437 name: Anopheles pullus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles yatsushiroensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003438 name: Anopheles punctimacula def: "A species of subgenus Anopheles, which acts as a major Central & South American malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles strigimacula" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles venezuelae" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003439 name: Anopheles punctipennis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles hyemalis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles stonei" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003440 name: Anopheles pursati def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003441 name: Anopheles quadrimaculatus def: "A species of subgenus Anopheles, which acts as a major North American malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles annulimanus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003442 name: Anopheles rachoui def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003443 name: Anopheles reidi def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003444 name: Anopheles roperi def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003445 name: Anopheles sacharovi def: "A species of subgenus Anopheles, which acts as a major North Eurasian & Mediterranean/Indo-Iranian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles elutus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003446 name: Anopheles samarensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003447 name: Anopheles saperoi def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003448 name: Anopheles ohamai def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003449 name: Anopheles separatus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles snijdersi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003450 name: Anopheles shannoni def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003451 name: Anopheles similissimus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles similis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003452 name: Anopheles sinensis def: "A species of subgenus Anopheles, which acts as a major Chinese malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles esoensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles plumiger" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003453 name: Anopheles sineroides def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003454 name: Anopheles sintoni def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003455 name: Anopheles sintonoides def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003456 name: Anopheles smaragdinus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003457 name: Anopheles stigmaticus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003458 name: Anopheles stricklandi def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003459 name: Anopheles symesi def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003460 name: Anopheles tasmaniensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003461 name: Anopheles tenebrosus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles subtilis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003462 name: Anopheles tibiamaculatus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003463 name: Anopheles tigertti def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003464 name: Anopheles umbrosus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles novumbrosus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003465 name: Anopheles vanus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003466 name: Anopheles veruslanei def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003467 name: Anopheles vestitipennis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003468 name: Anopheles vietnamensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003469 name: Anopheles walkeri def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003470 name: Anopheles wellingtonianus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003471 name: Anopheles whartoni def: "A species of subgenus Anopheles, which acts as a minor Malaysian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003472 name: Anopheles xiaokuanus def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003473 name: Anopheles xelajuensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003474 name: Anopheles ziemanni def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003475 name: Anopheles fluviatilis def: "A species of subgenus Cellia, which acts as a major Indo-Chinese & Indo-Iranian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles arabica" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles leptomeres" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles listonii" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003476 name: Anopheles fontinalis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003477 name: Anopheles freetownensis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003478 name: Anopheles funestus sensu lato def: "A species complex of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles anisochloros" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles bisignata" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles funestus s.l." EXACT [] synonym: "Anopheles funestus sl" EXACT [] synonym: "Anopheles hebes" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles imerinensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles kumasii" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles subumbrosa" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles umbrosa" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003479 name: Anopheles fuscivenosus def: "A member species of the species complex Anopheles funestus sensu lato." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003478 ! Anopheles funestus sensu lato [Term] id: MIRO:40003480 name: Anopheles gambiae sensu lato def: "A species complex of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles costalis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles gambiae s.l." EXACT [KL:KL] synonym: "Anopheles gambiae sl" EXACT [KL:KL] synonym: "Anopheles gracilis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles minor" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles typicus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003481 name: Anopheles garnhami def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles walshi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003482 name: Anopheles gibbinsi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles kibena" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003483 name: Anopheles grassei def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003484 name: Anopheles greeni def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003485 name: Anopheles grenieri def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003486 name: Anopheles griveaudi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003487 name: Anopheles hackeri def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003488 name: Anopheles hamoni def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003489 name: Anopheles hancocki def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003490 name: Anopheles hargreavesi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003491 name: Anopheles harperi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003492 name: Anopheles hervyi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003493 name: Anopheles hilli def: "A species of subgenus Cellia, which acts as a minor Australasian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003494 name: Anopheles hughi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003495 name: Anopheles incognitus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003496 name: Anopheles indefinitus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles formosaensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles II" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles malayensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles trimaculatus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003497 name: Anopheles introlatus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003498 name: Anopheles jamesii def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003499 name: Anopheles jebudensis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003500 name: Anopheles jeyporiensis def: "A species of subgenus Cellia, which acts as a minor Asian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles candidiensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles jeyporensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles tonkinensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003501 name: Anopheles karwari def: "A species of subgenus Cellia, which acts as a minor Australasian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles nigrans" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003502 name: Anopheles keniensis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003503 name: Anopheles kingi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003504 name: Anopheles kochi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles flava" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles halli" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles ocellatus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003505 name: Anopheles kolambuganensis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003506 name: Anopheles koliensis def: "A species of subgenus Cellia, which acts as a major Australasian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003507 name: Anopheles kosiensis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003508 name: Anopheles lacani def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003509 name: Anopheles leesoni def: "A member species of the species complex Anopheles funestus sensu lato." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003478 ! Anopheles funestus sensu lato [Term] id: MIRO:40003510 name: Anopheles letabensis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003511 name: Anopheles leucosphyrus def: "A species of subgenus Cellia, which acts as a major Malaysian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003512 name: Anopheles limosus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003513 name: Anopheles listeri def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003514 name: Anopheles litoralis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003515 name: Anopheles lloreti def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003516 name: Anopheles longipalpis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003517 name: Anopheles longirostris def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003518 name: Anopheles lounibosi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003519 name: Anopheles lovettae def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003520 name: Anopheles ludlowae def: "A species of subgenus Cellia, which acts as a major Malaysian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles cabrerai" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles formosensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles hatorii" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles torakala" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles Variety:" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003521 name: Anopheles torakala def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003522 name: Anopheles lungae def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003523 name: Anopheles macarthuri def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003524 name: Anopheles machardyi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003525 name: Anopheles maculatus def: "A species of subgenus Cellia, which acts as a major Malaysian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles hanabusai" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003526 name: Anopheles maculipalpis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003527 name: Anopheles majidi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003528 name: Anopheles maliensis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003529 name: Anopheles mangyanus def: "A species of subgenus Cellia, which acts as a minor Malaysian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles febrifera" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003530 name: Anopheles marshallii def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles pitchfordi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles pseudocostalis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles transvaalensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003531 name: Anopheles mascarensis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003532 name: Anopheles melas def: "A member species of the species complex Anopheles gambiae sensu lato, which acts as a minor Afrotropical malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003480 ! Anopheles gambiae sensu lato relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003533 name: Anopheles meraukensis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003534 name: Anopheles merus def: "A member species of the species complex Anopheles gambiae sensu lato, which acts as a minor Afrotropical malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles litoralis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles tangensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003480 ! Anopheles gambiae sensu lato relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003535 name: Anopheles millecampsi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003536 name: Anopheles milloti def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003537 name: Anopheles minimus def: "A species of subgenus Cellia, which acts as a major Malaysian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles alboapicalis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles christophersi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles cohaesa" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles formosaensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles I" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles vincenti" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003538 name: Anopheles moghulensis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003539 name: Anopheles mortiauxi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003540 name: Anopheles moucheti def: "A species of subgenus Cellia, which acts as a minor Afrotropical malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003541 name: Anopheles nigeriensis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003542 name: Anopheles bervoetsi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003543 name: Anopheles mousinhoi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003544 name: Anopheles multicinctus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles basilewskyi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles puselis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles Subspecies:" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003545 name: Anopheles basilewskyi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003546 name: Anopheles multicolor def: "A species of subgenus Cellia, which acts as a minor Afro-Arabian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles chaudoyei" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles impunctus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles nigrifasciatus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003547 name: Anopheles murphyi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003548 name: Anopheles natalensis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles aureosquamiger" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003549 name: Anopheles nataliae def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003550 name: Anopheles nemophilous def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003551 name: Anopheles nili def: "A species of subgenus Cellia, which acts as a minor Afrotropical malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles nigra" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles unicolor" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003552 name: Anopheles nivipes def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003553 name: Anopheles njombiensis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003554 name: Anopheles notanandai def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003555 name: Anopheles notleyi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003556 name: Anopheles novaguinensis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles breinli" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003557 name: Anopheles pallidus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles fowleri" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003558 name: Anopheles paltrinieri def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003559 name: Anopheles pampanai def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003560 name: Anopheles parangensis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003561 name: Anopheles parensis def: "A member species of the species complex Anopheles funestus sensu lato." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003478 ! Anopheles funestus sensu lato [Term] id: MIRO:40003562 name: Anopheles pattoni def: "A species of subgenus Cellia, which acts as a minor North Eurasian & Chinese malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003563 name: Anopheles pauliani def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003564 name: Anopheles pharoensis def: "A species of subgenus Cellia, which acts as a major Afro-Arabian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles albofimbriatus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles albus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles bozasi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles maculicosta" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003565 name: Anopheles philippinensis def: "A species of subgenus Cellia, which acts as a minor Indo-Iranian & Malaysian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles freerae" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles hainanensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles pampangensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003566 name: Anopheles pretoriensis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles tibani" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003567 name: Anopheles pseudojamesi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles ramsayi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003568 name: Anopheles pseudowillmori def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003569 name: Anopheles pujutensis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003570 name: Anopheles pulcherrimus def: "A species of subgenus Cellia, which acts as a minor Indo-Iranian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles atropotenae" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003571 name: Anopheles punctulatus def: "A species of subgenus Cellia, which acts as a major Australasian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003572 name: Anopheles quadriannulatus def: "A member species of the species complex Anopheles gambiae sensu lato." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003480 ! Anopheles gambiae sensu lato [Term] id: MIRO:40003573 name: Anopheles davidsoni def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003574 name: Anopheles radama def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003575 name: Anopheles ranci def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003576 name: Anopheles rageaui def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003577 name: Anopheles rennellensis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003578 name: Anopheles rhodesiensis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles aegypti" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles dthalisimilis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles rupicola" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles Subspecies:" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003579 name: Anopheles rupicola def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003580 name: Anopheles riparis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003581 name: Anopheles rivulorum def: "A member species of the species complex Anopheles funestus sensu lato." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles garnhamellus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003478 ! Anopheles funestus sensu lato [Term] id: MIRO:40003582 name: Anopheles rodhaini def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003583 name: Anopheles roubaudi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003584 name: Anopheles ruarinus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003585 name: Anopheles rufipes def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles broussesi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles brucechwatti" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles ingrami" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles seneveti" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles Subspecies:" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles watsoni" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003586 name: Anopheles broussesi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003587 name: Anopheles salbaii def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003588 name: Anopheles saungi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003589 name: Anopheles sawadwongporni def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003590 name: Anopheles schueffneri def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003591 name: Anopheles schwetzi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles michaeli" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003592 name: Anopheles seretsei def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003593 name: Anopheles sergentii def: "A species of subgenus Cellia, which acts as a major Afro-Arabian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles barkhuusi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles macmahoni" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles Subspecies:" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003594 name: Anopheles macmahoni def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003595 name: Anopheles seydeli def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003596 name: Anopheles smithii def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles cavernicola" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles pallidopalpi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003597 name: Anopheles solomonis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003598 name: Anopheles somalicus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003599 name: Anopheles splendidus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles indiensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003600 name: Anopheles squamosus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles arnoldi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles pretoriensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles tananariviensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003601 name: Anopheles stephensi def: "A species of subgenus Cellia, which acts as a minor Indo-Iranian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles folquei" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles intermedia" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles metaboles" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles mysorensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003602 name: Anopheles stookesi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003603 name: Anopheles subpictus def: "A species of subgenus Cellia, which acts as a major Malaysian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles error" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles rossii" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003604 name: Anopheles sulawesi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003605 name: Anopheles sundaicus def: "A species of subgenus Cellia, which acts as a major Malaysian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003606 name: Anopheles superpictus def: "A species of subgenus Cellia, which acts as a major Mediterranean & Indo-Iranian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles atheniensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles berestnevi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles cardamatisi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles hellenicus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles macedoniensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles nursei" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles palestinensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles vassilievii" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003607 name: Anopheles swahilicus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003608 name: Anopheles takasagoensis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003609 name: Anopheles tchekedii def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003610 name: Anopheles tessellatus def: "A species of subgenus Cellia, which acts as a minor Indo-Iranian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles ceylonica" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles deceptor" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles formosae" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles kalawara" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles kinoshitai" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles orientalis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles taiwanensis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles thorntonii" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles Variety:" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003611 name: Anopheles orientalis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003612 name: Anopheles kalawara def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003613 name: Anopheles theileri def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles albipes" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003614 name: Anopheles theobaldi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003615 name: Anopheles turkhudi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles amutis" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles azriki" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles flaviceps" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles persicus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles telamali" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles Variety:" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003616 name: Anopheles telamali def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003617 name: Anopheles ungujae def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003618 name: Anopheles vagus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles albino" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles flava" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles flavescens" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles immaculata" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles immaculatus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003619 name: Anopheles vaneedeni def: "A member species of the species complex Anopheles funestus sensu lato." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003478 ! Anopheles funestus sensu lato [Term] id: MIRO:40003620 name: Anopheles vanhoofi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003621 name: Anopheles varuna def: "A species of subgenus Cellia, which acts as a minor Indo-Iranian malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003622 name: Anopheles vernus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003623 name: Anopheles vinckei def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003624 name: Anopheles walravensi def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003625 name: Anopheles watsonii def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003626 name: Anopheles wellcomei def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles milesi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles Subspecies:" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles ugandae" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003627 name: Anopheles ugandae def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003628 name: Anopheles willmori def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles dudgeonii" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles indica" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles maculosa" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003629 name: Anopheles wilsoni def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003630 name: Kerteszia def: "A subgenus of genus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000015 ! genus Anopheles [Term] id: MIRO:40003631 name: Anopheles auyantepuiensis def: "A species of subgenus Kerteszia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003630 ! Kerteszia [Term] id: MIRO:40003632 name: Anopheles bambusicolus def: "A species of subgenus Kerteszia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003630 ! Kerteszia [Term] id: MIRO:40003633 name: Anopheles bellator def: "A species of subgenus Kerteszia, which acts as a minor South American malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles bromelicola" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003630 ! Kerteszia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003634 name: Anopheles boliviensis def: "A species of subgenus Kerteszia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003630 ! Kerteszia [Term] id: MIRO:40003635 name: Anopheles cruzii def: "A species of subgenus Kerteszia, which acts as a minor South American malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles adolphoi" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles Lutzii" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles montemor" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003630 ! Kerteszia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003636 name: Anopheles gonzalezrinconesi def: "A species of subgenus Kerteszia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003630 ! Kerteszia [Term] id: MIRO:40003637 name: Anopheles homunculus def: "A species of subgenus Kerteszia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles anoplus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003630 ! Kerteszia [Term] id: MIRO:40003638 name: Anopheles laneanus def: "A species of subgenus Kerteszia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003630 ! Kerteszia [Term] id: MIRO:40003639 name: Anopheles lepidotus def: "A species of subgenus Kerteszia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003630 ! Kerteszia [Term] id: MIRO:40003640 name: Anopheles neivai def: "A species of subgenus Kerteszia, which acts as a minor South American malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles hylephilus" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003630 ! Kerteszia relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003641 name: Anopheles pholidotus def: "A species of subgenus Kerteszia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003630 ! Kerteszia [Term] id: MIRO:40003642 name: Anopheles rollai def: "A species of subgenus Kerteszia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles hilli" RELATED [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003630 ! Kerteszia [Term] id: MIRO:40003643 name: Lophopodomyia def: "A subgenus of genus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000015 ! genus Anopheles [Term] id: MIRO:40003644 name: Anopheles gilesi def: "A species of subgenus Lophopodomyia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003643 ! Lophopodomyia [Term] id: MIRO:40003645 name: Anopheles gomezdelatorrei def: "A species of subgenus Lophopodomyia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003643 ! Lophopodomyia [Term] id: MIRO:40003646 name: Anopheles oiketorakras def: "A species of subgenus Lophopodomyia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003643 ! Lophopodomyia [Term] id: MIRO:40003647 name: Anopheles pseudotibiamaculatus def: "A species of subgenus Lophopodomyia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003643 ! Lophopodomyia [Term] id: MIRO:40003648 name: Anopheles squamifemur def: "A species of subgenus Lophopodomyia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003643 ! Lophopodomyia [Term] id: MIRO:40003649 name: Anopheles vargasi def: "A species of subgenus Lophopodomyia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40003643 ! Lophopodomyia [Term] id: MIRO:40003704 name: Anopheles persiensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003705 name: Anopheles nimpe def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003739 name: Anopheles hailarensis def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003748 name: Anopheles hinesorum def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003749 name: Anopheles torresiensis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003751 name: Anopheles halophylus def: "A species of subgenus Nyssorhynchus." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000070 ! Nyssorhynchus [Term] id: MIRO:40003756 name: Anopheles eouzani def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003757 name: Anopheles irenicus def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003766 name: Anopheles daciae def: "A species of subgenus Anopheles." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40000016 ! Anopheles [Term] id: MIRO:40003767 name: Anopheles ovengensis def: "A species of subgenus Cellia." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] is_a: MIRO:40002217 ! Cellia [Term] id: MIRO:40003829 name: Anopheles gambiae def: "A member species of the species complex Anopheles gambiae sensu lato, which acts as a major Afrotropical malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles gambiae s.s." EXACT [] synonym: "Anopheles gambiae sensu stricto" EXACT [] synonym: "Anopheles gambiae ss" EXACT [] is_a: MIRO:40003480 ! Anopheles gambiae sensu lato relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003830 name: Anopheles gambiae chromosomal form Bamako def: "A chromosomal form of Anopheles gambiae sensu stricto." [PMID:10645562 "Parassitologia. 1998 Dec;40(4):477-511."] synonym: "Anopheles gambiae s.s. chromosomal form Bamako " EXACT [] is_a: MIRO:40000803 ! Anopheles gambiae chromosomal form [Term] id: MIRO:40003831 name: Anopheles gambiae chromosomal form Mopti def: "A chromosomal form of Anopheles gambiae sensu stricto." [PMID:10645562 "Parassitologia. 1998 Dec;40(4):477-511."] synonym: "Anopheles gambiae s.s. chromosomal form Mopti" RELATED [] is_a: MIRO:40000803 ! Anopheles gambiae chromosomal form [Term] id: MIRO:40003832 name: Anopheles gambiae chromosomal form Savanna def: "A chromosomal form of Anopheles gambiae sensu stricto." [PMID:10645562 "Parassitologia. 1998 Dec;40(4):477-511."] synonym: "Anopheles gambiae s.s. chromosomal form Savanna" RELATED [] is_a: MIRO:40000803 ! Anopheles gambiae chromosomal form [Term] id: MIRO:40003833 name: Anopheles gambiae chromosomal form Forest def: "A chromosomal form of Anopheles gambiae sensu stricto." [PMID:10645562 "Parassitologia. 1998 Dec;40(4):477-511."] synonym: "Anopheles gambiae s.s. chromosomal form Forest" RELATED [] is_a: MIRO:40000803 ! Anopheles gambiae chromosomal form [Term] id: MIRO:40003834 name: Anopheles funestus def: "A member species of the species complex Anopheles funestus sensu lato, which acts as a major Afrotropical malaria vector." [Walter_Reed:taxonomy "http://www.mosquitocatalog.org/"] synonym: "Anopheles funestus s.s." EXACT [] synonym: "Anopheles funestus sensu stricto" EXACT [] synonym: "Anopheles funestus ss" EXACT [] is_a: MIRO:40003478 ! Anopheles funestus sensu lato relationship: has_role IDOMAL:0001061 ! malaria vector [Term] id: MIRO:40003835 name: Anopheles gambiae chromosomal form Bissau def: "A chromosomal form of Anopheles gambiae sensu stricto." [PMID:10645562 "Parassitologia. 1998 Dec;40(4):477-511."] synonym: "Anopheles gambiae s.s. chromosomal form Bissau" RELATED [] is_a: MIRO:40000803 ! Anopheles gambiae chromosomal form [Term] id: MIRO:40003836 name: Anopheles gambiae molecular form S def: "A molecular form of Anopheles gambiae sensu stricto, defined by the presence of a given haplotype of the rDNA intergenic spacer." [PMID:11240632 "Insect Mol Biol. 2001 Feb;10(1):9-18."] is_a: MIRO:40003065 ! Anopheles gambiae molecular form [Typedef] id: agent_in name: agent_in is_transitive: true [Typedef] id: happens_during name: happens_during def: "p happens_during s iff start_of(s) <= start_of(p) & end_of(p) <= end_of(s)." [:happens_during "http://obo.cvs.sourceforge.net/*checkout*/obo/obo/ontology/OBO_REL/ro_proposed.obo"] created_by: louis creation_date: 2009-06-29T12:56:19Z [Typedef] id: has_part name: has_part is_reflexive: true is_transitive: true inverse_of: part_of ! part_of is_anti_symmetric: true [Typedef] id: has_participant name: has_participant def: "P has_participant C if and only if: given any process p that instantiates P there is some continuant c, and some time t, such that: c instantiates C at t and c participates in p at t." [PMID:15892874] comment: Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time. inverse_of: participates_in ! participates_in [Typedef] id: has_role name: has_role alt_id: OBO_REL:0000033 def: "A relation between a continuant C and a role R. The reciprocal relation of role_of." [GOC:cjm] [Typedef] id: part_of name: part_of def: "For continuants: C part_of C' if and only if: given any c that instantiates C at a time t, there is some c' such that c' instantiates C' at time t, and c *part_of* c' at t. For processes: P part_of P' if and only if: given any p that instantiates P at a time t, there is some p' such that p' instantiates P' at time t, and p *part_of* p' at t. (Here *part_of* is the instance-level part-relation. )." [PMID:15892874] comment: Parthood as a relation between instances: The primitive instance-level relation p part_of p1 is illustrated in assertions such as: this instance of rhodopsin mediated phototransduction part_of this instance of visual perception. This relation satisfies at least the following standard axioms of mereology: reflexivity (for all p, p part_of p); anti-symmetry (for all p, p1, if p part_of p1 and p1 part_of p then p and p1 are identical); and transitivity (for all p, p1, p2, if p part_of p1 and p1 part_of p2, then p part_of p2). Analogous axioms hold also for parthood as a relation between spatial regions. For parthood as a relation between continuants, these axioms need to be modified to take account of the incorporation of a temporal argument. Thus for example the axiom of transitivity for continuants will assert that if c part_of c1 at t and c1 part_of c2 at t, then also c part_of c2 at t. Parthood as a relation between classes: To define part_of as a relation between classes we again need to distinguish the two cases of continuants and processes, even though the explicit reference to instants of time now falls away. For continuants, we have C part_of C1 if and only if any instance of C at any time is an instance-level part of some instance of C1 at that time, as for example in: cell nucleus part_ of cell. is_reflexive: true is_transitive: true inverse_of: has_part ! has_part is_anti_symmetric: true [Typedef] id: participates_in name: participates_in def: "C participates_in_some P if and only if: given any process p that instantiates P there is some continuant c, and some time t, such that: c instantiates C at t and c participates in p at t." [:participates_in "http://www.fruitfly.org/~cjm/ro/OBO_REL_C/0000020.html"] inverse_of: has_participant ! has_participant [Typedef] id: preceded_by name: preceded_by def: "P preceded_by P' if and only if: given any process p that instantiates P at a time t, there is some process p' such that p' instantiates P' at time t', and t' is earlier than t." [:preceded_by "http://www.obofoundry.org/ro/#preceded_by", PMID:15892874] comment: An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other. is_transitive: true inverse_of: precedes ! precedes created_by: Pantelis creation_date: 2009-07-08T10:33:13Z [Typedef] id: precedes name: precedes is_transitive: true inverse_of: preceded_by ! preceded_by [Typedef] id: realized_by name: realized_by alt_id: OBO_REL:0000035 alt_id: OBO_REL:realized_as def: "Relation between a realizable and a process. Reciprocal relation of realizes." [GOC:cjm] comment: NOTE: there appears to be some consistency in usage as to whether processes or continuants realize synonym: "executed_during" RELATED [] synonym: "has_realization" EXACT [] inverse_of: realizes ! realizes priority: 1-01 created_by: Pantelis creation_date: 2009-07-12T11:22:12Z [Typedef] id: realizes name: realizes alt_id: OBO_REL:0000034 def: "Relation between a process and a function, where the unfolding of the process requires the execution of the function. Class level: P realizes F iff: given any p that instantiates P, there exists some f, t such that f instantiates F at t and p *realizes* f. Here, *realizes* is the primitive instance level relation." [GOC:cjm] comment: The process of 'histidine catabolism' (GO:0006548) realizes the function 'histidine ammonia lyase activity' (GO:0004397) (note: here 'activity' denotes a function and not a process). We leave open the possibility of defining in future the sub-relations directly_realizes (as bewteen a function and it's functioning) and indirectly_realizes. NOTE: there appears to be some consistency in usage as to whether processes or continuants realize synonym: "executes" RELATED [] synonym: "has_function_part" EXACT [] synonym: "involves_execution_of" RELATED [] synonym: "is_realization_of" EXACT [] xref: OBO_REL:0000034 inverse_of: realized_by ! realized_by priority: 1-01 created_by: Pantelis creation_date: 2009-07-12T09:05:59Z