owl:Class
Breast Duct Lavage
Lavage
A minimally-invasive procedure that permits sampling of breast ductal fluids for cytopathologic analysis.
CL353163
Breast Duct Lavage
C51969
Diagnostic Procedure
Breast Duct Lavage
Breast Duct Lavage
Vaccine Therapy
Vaccine Therapy
Therapeutic or Preventive Procedure
Vaccine Therapy
Immunotherapy
Active immunization where vaccine is administered for therapeutic or preventive purposes. This can include administration of immunopotentiating agents such as BCG vaccine and Corynebacterium parvum as well as biological response modifiers such as interferons, interleukins, and colony-stimulating factors in order to directly stimulate the immune system.
owl:Class
C0042209
C15347
Vaccine Therapy
Instruction Imperative
Finish
Activity
Finish
C64943
owl:Class
Finish
CL370611
Complete
Finish
Acid Urate Crystal Measurement
CDISC SDTM Laboratory Test Terminology by Name
owl:Class
Acid Urate Crystal Measurement
Laboratory Procedure
C74912
<def-source>CDISC</def-source><def-definition>A measurement of the ammonium acid urate crystals present in a biological specimen.</def-definition>
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Code
Acid Urate Crystal Measurement
Acid Urate Crystal Measurement
CDISC SDTM Terminology
Clinical Data Interchange Standards Consortium Terminology
CL384364
CYACIDU
The determination of the amount of acid urate crystals present in a sample.
Crystal Growth Measurement
Acid Urate Crystals
CDISC
Autotransfusion Procedure
Reinfusion Procedure
Autotransfusion Procedure
Autotransfusion
CL354947
Blood Transfusion
Autotransfusion Procedure
Autotransfusion Procedure
Therapeutic or Preventive Procedure
Infusion of previously obtained autologous blood or blood products back to the same individual.
C50870
owl:Class
Diagnostic tests designed to be performed at specific age markers.
Age Appropriate Screening
Age Appropriate Screening
Disease Screening
owl:Class
Diagnostic Procedure
Age Appropriate Screening
Age Appropriate Screening
C81176
Removal of tissue from the kidney, for microscopic examination, using a needle.
Needle Biopsy of Kidney
Percutaneous Biopsy of Kidney
Needle Biopsy of Kidney
Needle Biopsy of Kidney
CL354730
C51764
Diagnostic Procedure
owl:Class
Needle Biopsy
Needle Biopsy of Kidney
Polymorphic Microsatellite Marker Analysis
owl:Class
CL365429
Polymorphic Microsatellite Marker Analysis
Polymorphic Microsatellite Marker Analysis
C63332
Molecular Analysis
Polymorphic Microsatellite Marker Analysis
Laboratory Procedure
Immunosuppressive Therapy
CL067992
T-Cell Depletion Therapy
owl:Class
T-Cell Depletion Therapy
<def-source>NCI-GLOSS</def-source><def-definition>Treatment to destroy T cells, which play an important role in the immune response. Elimination of T cells from a bone marrow graft from a donor may reduce the chance of an immune reaction against the recipient's tissues.</def-definition>
C15699
T-Cell Depletion Therapy
T-Lymphocyte Depletion Therapy
T-cell depletion
T-Cell Depletion
Therapeutic or Preventive Procedure
T-Cell Depletion Therapy
C0035345
To stop working at one's occupation; the state of being retired.
C78237
Activity
owl:Class
Retire
Retirement
Retirement
Retirement
Retirement
Retired
Action
CL355524
Therapeutic or Preventive Procedure
Suprapubic Prostatectomy
owl:Class
C51589
Procedure_May_Have_Partially_Excised_Anatomy some 'Seminal Vesicle'
Suprapubic Prostatectomy
Suprapubic Prostatectomy
Suprapubic Prostatectomy
Procedure_May_Have_Partially_Excised_Anatomy some 'Vas Deferens'
Prostatectomy
Prevention of Endometrial Cancer
Cancer Prevention
Therapeutic or Preventive Procedure
Prevention of Endometrial Cancer
C15674
owl:Class
Prevention of Endometrial Cancer
Prevention of Endometrial Cancer
CL031790
Endometrial Cancer Prevention
Stratified Random Sampling
C0681879
Random Sampling
owl:Class
Stratified Random Sampling
Stratified Random Sampling
Stratified Sampling
C71496
Quantitative Concept
Stratified Random Sampling
Discharge
Discharge
Health Care Activity
Discharge from Healthcare Facility
Patient Discharge
The release of a patient from a course of care.
Release
C25166
Discharge
Discharge
C0030685
Administrative Activity
owl:Class
Comparison of Screening Methods
Health Care Activity
CL035536
Comparison of Screening Methods
C62743
Disease Screening
owl:Class
Comparison of Screening Methods
Comparison of Screening Methods
Barbiturate Drug Class Measurement
owl:Class
Butalbital Measurement
Laboratory Procedure
C0202345
Butalbital Measurement
C75365
The determination of the amount of butalbital present in a sample.
Butalbital Measurement
Butalbital Measurement
Barium Enema Injection
Injection of a barium-containing contrast medium through the anus and into the lower gastrointestinal tract so that X-rays can be taken in order to identify lesions and other abnormal growths.
Barium Enema Injection
Enema Administration
owl:Class
Barium Enema Injection
<def-source>NCI-GLOSS</def-source><def-definition>X-rays of the colon and rectum (lower gastrointestinal tract) that are taken after a person is given a barium enema.</def-definition>
C0203075
<def-source>NCI-GLOSS</def-source><def-definition>A procedure in which a liquid with barium in it is put into the rectum and colon by way of the anus. Barium is a silver-white metallic compound that helps to show the image of the lower gastrointestinal tract on an x-ray.</def-definition>
Diagnostic Procedure
Barium Enema Injection
Barium Enema
Lower Gastrointestinal Series
barium enema
lower GI series
Lower GI Series
C1447
Prior Radiation Therapy
Prior Radiation
C15477
CL029245
Clinical Attribute
Prior Radiation Therapy
Prior Radiation Therapy
Prior RT
Prior Therapy
An indicator that a person has been previously received radiation treatment for the same condition.
Prior Radiotherapy
owl:Class
Prior Radiation Therapy
Neck Dissection
Therapeutic or Preventive Procedure
owl:Class
Selective Neck Dissection of Cervical Lymph Nodes
Selective Neck Dissection of Cervical Lymph Nodes
Selective Neck Dissection of Cervical Lymph Nodes
CL354215
C51786
Selective Neck Dissection of Cervical Lymph Nodes
Cystoscopy
CL370553
Therapeutic Cystoscopy
C64960
Therapeutic Cystoscopy
Therapeutic Endoscopic Procedure
Therapeutic Cystoscopy
owl:Class
Therapeutic or Preventive Procedure
Therapeutic Cystoscopy
laboratory study
C28278
C0681827
owl:Class
Research Activity
<def-source>NCI-GLOSS</def-source><def-definition>Research done in a laboratory. These studies may use test tubes or animals to find out if a drug, procedure, or treatment is likely to be useful. Laboratory studies take place before any testing is done in humans.</def-definition>
Laboratory Study
Laboratory Study
Laboratory Study
Laboratory Study
Research Activity
Genome Scan
Genome Scan
Laboratory Procedure
CL016067
To analyse the entire genome (total genetic complement) of an individual, organism, cell or tissue.
Molecular Genetic Technique
Genome Scan
C20092
owl:Class
Genome Scan
Surgical Procedure by Method
Radiosurgery
Radiosurgery
Therapeutic or Preventive Procedure
Therapeutic Surgical Procedure
radiation surgery
owl:Class
Radiation Therapy
Stereotactic External Beam Irradiation
<def-source>NCI-GLOSS</def-source><def-definition>A radiation therapy technique that delivers radiation directly to the tumor while sparing the healthy tissue.</def-definition>
C15696
radiosurgery
Radiosurgery
Radiation Surgery
CL031853
Radiosurgery
C74738
Clinical Data Interchange Standards Consortium Terminology
CDISC
CDISC SDTM Laboratory Test Terminology by Name
Globulin Protein Measurement
Globulin Protein Measurement
GLOBUL
CDISC SDTM Terminology
The determination of the amount of globulin protein present in a sample.
Protein or Enzyme Type Measurement
Laboratory Procedure
<def-source>CDISC</def-source><def-definition>A measurement of the globulin protein in a biological specimen.</def-definition>
owl:Class
CDISC SDTM Laboratory Test Terminology by Code
CDISC SEND Terminology
Globulin Protein Measurement
Globulin
Globulin Protein Measurement
C0877347
Nanoparticle Chemical Characterization
Activity
Analyses to determine the chemical properties of a nanoparticle. These chemical elements are requisites for molecular structure, and they determine both the reactivity and selectivity of nanoparticles.
Nanoparticle Chemical Characterization
owl:Class
C62334
Nanoparticle Chemical Characterization
Nanoparticle Chemical Characterization
CL364925
Physical Chemical Technique
Diagnostic Thoracoscopy
C64947
Diagnostic Procedure
Diagnostic Thoracoscopy
Diagnostic Thoracoscopy
CL370149
Diagnostic Endoscopic Procedure
owl:Class
Thoracoscopy
Diagnostic Thoracoscopy
owl:Class
Biopsy of Testis
CL354450
Biopsy
Removal of testicular tissue for microscopic examination.
Biopsy of Testis
Biopsy of Testis
Diagnostic Procedure
Procedure_Has_Partially_Excised_Anatomy only Testis
Biopsy of Testis
C51894
chemical immunotherapy for cancer
Chemical Cancer Immunotherapy
Chemical Cancer Immunotherapy is the use of chemical substances to alter the interaction between the host's immune defenses and cancer cells to boost, direct, or restore the body's ability to fight cancer.
owl:Class
C15975
CL003751
Chemical Cancer Immunotherapy
Cancer Immunotherapy
Immunotherapy, Cancer, Chemical
Chemical Immunotherapy
Therapeutic or Preventive Procedure
Chemical Cancer Immunotherapy
Chemical Cancer Immunotherapy
Laboratory Procedure
Cell Culture
Tissue Culture
owl:Class
Cell Culture
Cell Culture
C0007585
<def-source>NCI-GLOSS</def-source><def-definition>Animal or human cells that are grown in the laboratory.</def-definition>
cultured cells
C16396
Cell Culture
General term referring to the maintenance of cell strains or lines in the laboratory.
C73490
Immune Cell Function Assay
Cellular Assay
A set of laboratory assays that examine the responses of lymphoid or myeloid cells after exposure to an experimental material.
Immune Cell Function
CL383680
Immune Cell Function Assay
Immune Cell Function Assay
owl:Class
Research Activity
Immune Cell Function Assay
Biopsy of Bone
Biopsy of Bone
CL354437
Bone Biopsy
Diagnostic Procedure
Biopsy
Biopsy of Bone
owl:Class
C51927
Procedure_Has_Partially_Excised_Anatomy only Bone
Biopsy of Bone
Removal of bone tissue for microscopic examination.
Self-Etching Bonding System
Using an acid to condition tooth dentin, resulting in a superficial demineralization of dentin, allowing a low-viscosity monomer to be diffused into the evacuated spaces creating micro retention that results in bond strength approaching the inherent strength of dentin itself.
owl:Class
Self-Etching Bonding System
C52579
CL356750
Therapeutic or Preventive Procedure
Self-Etching Bonding System
Self-Etching Bonding System
Dental Procedure
Diagnostic Procedure
Id Lymph Vaccine Test
Id Lymph Vaccine Test
Skin Test
Id Lymph Vaccine Test
owl:Class
CL319745
Id Lymph Vaccine Test
Id Lymph Skin Test
A test consisting of a lymphoma idiotype (Id)-specific protein conjugated to the immunogen keyhole limpet hemocyanin (KLH). As a test of innate host delayed-type hypersensitivity (DTH) and host DTH in response to therapeutic vaccination, Id lymph vaccine test is performed intradermally before and after therapeutic vaccination in lymphoma patients treated with Id-specific vaccines. (NCI04)
C29110
Therapeutic or Preventive Procedure
Endodontic Procedure
Endodontic Treatment
C0700632
Dental Procedure
Endodontic Treatment
Endodontic Treatment
C52575
owl:Class
Endodontic Treatment
Dental procedures to treat disease or injury to the tooth pulp, and may include palliative treatment.
Surgical removal of part of the ethmoid bone, using an intra-nasl approach.
Therapeutic or Preventive Procedure
Procedure_Has_Partially_Excised_Anatomy only 'Ethmoid Bone'
Intranasal Ethmoidectomy
Intranasal Ethmoidectomy
Intranasal Ethmoidectomy
Intranasal Ethmoidectomy
Head and Neck Surgery
C51898
owl:Class
CL353462
The determination of the amount of alpha-2 macroglobulin present in a sample.
Alpha-2 Macroglobulin Measurement
Alpha-2 Macroglobulin Measurement
Alpha-2 Macroglobulin Measurement
Laboratory Procedure
Alpha-2 Macroglobulin Measurement
Protein or Enzyme Type Measurement
owl:Class
C80168
Extubation
The removal of a previously inserted tube from a hollow organ or passageway, often from the airway.
FDA
Extubation
Extubate
Patient Code (Appendix B)
Detubation
Extubation
C50819
Therapeutic Procedure
Health Care Activity
CL353915
Patient Problem Codes FDA CDRH
owl:Class
Extubation
A sample of blood applied in a thin film to a microscope slide for study under a microscope.
Blood Smear
owl:Class
Hematology Test
Blood Smear
C79903
Blood Smear
Blood Smear
Laboratory Procedure
Equilibrium Phase Spiral CT
Equilibrium Phase Spiral CT
Equilibrium Phase Spiral CT
CL009737
C19911
Phased Spiral CT
A type of computed tomography whereby images are taken following administration of contrast medium. The equilibrium phase is defined as the time period in which the contrast medium has reached a stable equilibrium within the body tissues. Images taken within the equilibrium phase tend to not show a very clear contrast between structures.
Equilibrium Phase Spiral CT
owl:Class
Diagnostic Procedure
Laboratory Procedure
Cytotoxic T-Lymphocyte Analysis
CL027900
Cytotoxic T-Lymphocyte Analysis
owl:Class
C19357
Cytotoxic T-Lymphocyte Analysis
CTL Analysis
Cytotoxic T-Lymphocyte Analysis
Bioassay, in vitro
Cancer Screening
owl:Class
CL030583
Screening for Gastric Cancer
gastric cancer early detection
screening for stomach cancer
C15567
Screening for Gastric Cancer
early detection of gastric cancer
Screening for Gastric Cancer
gastric cancer screening
stomach cancer early detection
early detection of stomach cancer
Diagnostic Procedure
Screening for Gastric Cancer
stomach cancer screening
CL371540
Nutritional Intervention
Therapeutic or Preventive Procedure
owl:Class
Nutritional Intervention
Intervention or Procedure
Nutritional Intervention
Nutritional Intervention
C67022
Respiratory Therapy
Respiratory Therapy
owl:Class
Respiratory Therapy
<def-source>CSP2000</def-source><def-definition>care of patients with deficiencies and abnormalities associated with the pulmonary system.</def-definition>
Respiratory Therapy
<def-source>MSH2001</def-source><def-definition>Care of patients with deficiencies and abnormalities associated with the cardiopulmonary system. It includes the therapeutic use of medical gases and their administrative apparatus, environmental control systems, humidification, aerosols, ventilatory support, bronchopulmonary drainage and exercise, respiratory rehabilitation, assistance with cardiopulmonary resuscitation, and maintenance of natural, artificial, and mechanical airways.</def-definition>
Therapeutic or Preventive Procedure
respiratory therapy
C15322
C0035239
Rehabilitation
<def-source>NCI-GLOSS</def-source><def-definition>(RES-pih-ra-tor-ee) Exercises and treatments that help improve or restore lung function.</def-definition>
Procedure_Has_Excised_Anatomy only 'Left Ovary'
C51925
CL353516
Left Salpingo-Oophorectomy
Salpingo-Oophorectomy
Left Salpingo-Oophorectomy
owl:Class
Surgical removal of the left fallopian tube and left ovary.
Procedure_Has_Excised_Anatomy only 'Left Fallopian Tube'
Left Salpingo-Oophorectomy
Left Salpingo-Oophorectomy
Therapeutic or Preventive Procedure
Computed Tomography Laser Mammography
C71751
CL378266
Computed Tomography Laser Mammography
Computed Tomography Laser Mammography
Computed Tomography Laser Mammography
Diagnostic Procedure
Computed Tomography
Mammography
owl:Class
Do Not Fill Before
Do Not Fill Before
Do Not Fill Before
Activity
Do Not Fill Before
CL371413
owl:Class
C67009
Instruction Imperative
Molecular Biology Research Technique
Cloning
Cloning
Cloning
C0009015
Any of the techniques that produce identical individuals.
C16442
Molecular Genetic Technique
owl:Class
Cloning
C64488
Calcium
Clinical Data Interchange Standards Consortium Terminology
Calcium Measurement
A quantitative measurement of the amount of calcium present in a sample.
Calcium Measurement
CDISC
owl:Class
C0201925
Calcium Measurement
CDISC SDTM Laboratory Test Terminology by Name
CA
CDISC SEND Terminology
CDISC SDTM Terminology
Chemistry Test
<def-source>CDISC</def-source><def-definition>A measurement of the calcium in a biological specimen.</def-definition>
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Code
Calcium Measurement
Diagnostic Imaging
C16502
Imaging Technique
owl:Class
C0011923
Diagnostic Procedure
Any method that uses a visual display of structural or functional patterns of organs or tissues for diagnostic evaluation.
Diagnostic Imaging
Diagnostic Imaging
Diagnostic Imaging
CL354267
Procedure_Has_Target_Anatomy only Blood
Thrombectomy
Therapeutic or Preventive Procedure
Thrombectomy
Thrombectomy
owl:Class
Surgery performed with the purpose of removing a thrombus.
Procedure_Has_Target_Anatomy only 'Blood Vessel'
Thrombectomy
C52003
Cardiovascular Surgical Procedure
Nutrition Monitoring
Nutrition Monitoring
CL004701
owl:Class
Nutrition Monitoring
Nutrition Monitoring
Any method for determining as accurately as possible total food amount and composition ingested by subjects in dietary studies or amount of specific dietary components.
Therapeutic or Preventive Procedure
Nutritional Study
C16021
Right Heart Catheterization
owl:Class
Health Care Activity
Swan-Ganz Catheterization
A diagnostic procedure in which a catheter is guided into the right heart, where pressures may be measured and radiocontrast material may be injected to visualize blood flow in and around the right heart.
Right Heart Catheterization
Cardiac Catheterization
C80411
Right Heart Catheterization
Right Heart Catheterization
Pulmonary Artery Catheterization
Alpha1
Qualitative Concept
CL371498
The significance level for the detection p-value in an absolute analysis.
Alpha1 Significance
Alpha1 Significance
owl:Class
Statistical Significance
C67050
Alpha1 Significance
Alpha1 Significance
controlled study
Controlled Study
C28279
Controlled Study
<def-source>NCI-GLOSS</def-source><def-definition>An experiment or clinical trial that includes a comparison (control) group.</def-definition>
Research Activity
C0681867
Controlled Study
Study Design
Controlled Study
owl:Class
Use Your Judgement
Activity
Use Your Judgement
CL371571
owl:Class
C67008
Use Your Judgement
Instruction Imperative
Use Your Judgement
CDC Behavioral Risk Factor Surveillance Survey
CDC Behavioral Risk Factor Surveillance Survey
owl:Class
Health Care Activity
CDC Behavioral Risk Factor Surveillance Survey
C16131
CDC Behavioral Risk Factor Surveillance Survey
CL014037
Cancer Surveillance Project
Nutrition Research, Applied Clinical Trials
Research Activity
Applied Research
C15821
Nutrition Research, Applied Clinical Trials
Nutrition Research, Applied Clinical Trials
CL000600
owl:Class
Nutrition Research, Applied Clinical Trials
C51953
Microbial Colony Count
Microbial Colony Count
CL354087
owl:Class
Microbiology Test
Microbial Colony Count
Microbial Colony Count
Laboratory Procedure
Incidental Appendectomy
Appendectomy
owl:Class
C51888
Incidental Appendectomy
CL354657
Incidental Appendectomy
Surgical removal of the vermiform appendix, performed incidentally to another primary surgical procedure.
Therapeutic or Preventive Procedure
Incidental Appendectomy
C66866
CL371163
owl:Class
High Efficiency Particulate Air-Filtered Environment
High Efficiency Particulate Air-Filtered Environment
Supportive Care
High Efficiency Particulate Air-Filtered Environment
High Efficiency Particulate Air-Filtered Environment
HEPA-Filtered Environment
Health Care Activity
Dental Procedure
C63715
Dental Pulp Capping
Dental Pulp Capping
Dental Pulp Cap
owl:Class
Dental Pulp Capping
Application of a protective agent to an exposed pulp (direct capping) or the remaining thin layer of dentin over a nearly exposed pulp (indirect capping) in order to allow the pulp to recover and maintain its normal vitality and function.
Dental Pulp Capping
C0011402
Therapeutic or Preventive Procedure
Admission
C0809949
Action
Admission
The condition of being allowed to enter; the activity of admitting someone to something.
Activity
owl:Class
Admission
C25385
Admission
CDISC SDTM Laboratory Test Terminology by Name
<def-source>CDISC</def-source><def-definition>A measurement of the Helmet cells (specialized Keratocytes with two projections on either end that are tapered and hornlike) in a biological specimen.</def-definition>
C74658
CL384395
Helmet Cell Count
CDISC SDTM Laboratory Test Terminology by Code
CDISC
CDISC SEND Terminology
Helmet Cell Count
The determination of the number of helmet cells present in a sample.
Helmet Cell Count
Clinical Data Interchange Standards Consortium Terminology
owl:Class
Helmet Cells
CDISC SDTM Terminology
HELMETCE
Schistocyte Count
Laboratory Procedure
Helmet Cell Count
Lung Transplantation
C0024128
Organ Transplantation
<def-source>MSH2001</def-source><def-definition>The transference of either one or both of the lungs from one human or animal to another.</def-definition>
Lung Transplantation
Lung Transplantation
Thoracic Surgical Procedure
owl:Class
Procedure_Has_Excised_Anatomy only Lung
lung grafting
Therapeutic or Preventive Procedure
Lung Transplantation
C15274
Kidney Biopsy
Percutaneous Renal Biopsy
C51901
Diagnostic Procedure
CL353593
Percutaneous Biopsy of Kidney
Removal of tissue from the kidney, for microscopic examination, obtained percutaneously.
Percutaneous Biopsy of Kidney
Percutaneous Biopsy of Kidney
Percutaneous Biopsy of Kidney
owl:Class
Core Biopsy
owl:Class
<def-source>NCI-GLOSS</def-source><def-definition>The removal of a tissue sample with a needle for examination under a microscope.</def-definition>
core biopsy
Diagnostic Procedure
Needle Biopsy
Core Biopsy
C1318309
Core Needle Biopsy
The removal of a tissue sample using a needle with a relatively large diameter, for microscopic examination.
Core Biopsy
C15680
Core Biopsy
Therapeutic or Preventive Procedure
Head and Neck Surgery
Head and Neck Surgery
CL029132
C15454
Procedure_Has_Target_Anatomy only 'Head and Neck'
owl:Class
Head and Neck Surgery
Surgical Procedure by Site or System
Head and Neck Surgery
CL355823
owl:Class
Unadjusted Mortality Rate
Death Rate
Quantitative Concept
Unadjusted Mortality Rate
Unadjusted Mortality Rate
C53359
Unadjusted Mortality Rate
Clinical Data Interchange Standards Consortium Terminology
Prolactin Measurement
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Name
Prolactin
Hormone Measurement
Laboratory Procedure
Prolactin Measurement
Prolactin Measurement
C0373706
<def-definition>A measurement of the prolactin hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
C74870
CDISC SEND Terminology
owl:Class
Prolactin Measurement
The determination of the amount of prolactin hormone present in a sample.
PROLCTN
Neurologic Examination
Neurologic Examination
owl:Class
C81313
Newborn Screening
Medical Examination
Diagnostic Procedure
Neurologic Examination
Neurologic Examination
The assessment of the functionality of the brain, spinal column, and nerves.
Therapeutic or Preventive Procedure
C70612
Tolerance Induction Pre-Solid Organ Transplant
Tolerance Induction Pre-Solid Organ Transplant
Tolerance Induction Pre-Solid Organ Transplant
Tolerance Induction Pre-Solid Organ Transplant
owl:Class
A procedure to establish immune suppression of the host in preparation for solid organ transplant to avoid organ rejection.
CL376056
Therapeutic Procedure
C50821
Foreign Body Removal
owl:Class
Therapeutic or Preventive Procedure
Foreign Body Removal
C0184937
Therapeutic Procedure
Foreign Body Removal
Foreign Body Removal
C64432
Protein or Enzyme Type Measurement
CDISC SEND Terminology
owl:Class
ALP
Laboratory Procedure
Alkaline Phosphatase Measurement
Alkaline Phosphatase Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the alkaline phosphatase in a biological specimen.</def-definition>
Liver Function Test
A quantitative measurement of alkaline phosphatase present in a sample.
CDISC SDTM Terminology
C0201850
Alkaline Phosphatase Measurement
Alkaline Phosphatase Measurement
Clinical Data Interchange Standards Consortium Terminology
CDISC
CDISC SDTM Laboratory Test Terminology by Name
Alkaline Phosphatase
CDISC SDTM Laboratory Test Terminology by Code
Benzoylecgonine Measurement
Laboratory Procedure
C75350
The determination of the amount of benzoylecgonine, the primary metabolite of cocaine, present in a sample.
Cocaine Measurement
C0524029
owl:Class
Benzoylecgonine Measurement
Benzoylecgonine Measurement
Benzoylecgonine Measurement
CL378106
C71510
Critical-Case Sampling
Critical-Case Sampling
Matched Sampling
owl:Class
Critical-Case Sampling
Critical-Case Sampling
Quantitative Concept
Clinical Attribute
C0232970
Postmenopausal
postmenopausal
Menopausal Status
C15421
Postmenopausal
owl:Class
<def-source>NCI-GLOSS</def-source><def-definition>Refers to the time after menopause. Menopause is the time in a woman's life when menstrual periods stop permanently; also called "change of life."</def-definition>
Postmenopausal
Postmenopausal
CDISC SEND Terminology
Heinz-Erhlich Bodies
owl:Class
CDISC SDTM Laboratory Test Terminology by Code
Hematology Test
Clinical Data Interchange Standards Consortium Terminology
HEINZ
CDISC
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
Heinz-Ehrlich Body Measurement
C74709
Heinz-Ehrlich Body Measurement
Heinz Bodies
CDISC SDTM Terminology
Heinz-Ehrlich Body Measurement
CL384699
Heinz-Ehrlich Body Measurement
The determination of the amount of Heinz bodies (denatured hemoglobin) present in a sample.
<def-source>CDISC</def-source><def-definition>A measurement of the Heinz bodies (small round inclusions within the body of a red blood cell) in a biological specimen.</def-definition>
A program of the CDC. Established by an act of Congress in 1990 it provides for screening exams to underserved women.
owl:Class
Cancer Research
CL014703
Health Care Related Organization
National Breast and Cervical Cancer Early Detection Program
National Breast and Cervical Cancer Early Detection Program
National Breast and Cervical Cancer Early Detection Program
C16173
Women's Health Check Program
NBCCEDP
National Breast and Cervical Cancer Early Detection Program
owl:Class
CDISC SDTM Terminology
C0373595
<def-source>CDISC</def-source><def-definition>A measurement of the volume of serum or plasma that would be cleared of creatinine by excretion of urine for a specified unit of time (e.g. one minute).</def-definition>
CDISC SDTM Laboratory Test Terminology by Code
C25747
Creatinine Clearance
CDISC
Renal Clearance
The determination of the clearance of endogenous creatinine, used for evaluating the glomerular filtration rate.
Creatinine Clearance
CDISC SDTM Laboratory Test Terminology by Name
Creatinine Clearance
Creatinine Clearance
CREATCLR
CDISC SEND Terminology
Clinical Data Interchange Standards Consortium Terminology
Laboratory Procedure
Clinical Trials Design
Health Care Activity
CL001220
Evaluation of Risk Factors
Evaluation of Risk Factors
C15892
Evaluation of Risk Factors
Evaluation of Risk Factors
owl:Class
Pancreatoduodenectomy
Pancreatoduodenectomy
Therapeutic or Preventive Procedure
Pancreatoduodenectomy
Pancreatoduodenectomy
CL354133
Abdominal Surgical Procedure
C51933
owl:Class
Imaging Biomarker Analysis
Imaging Biomarker Analysis
Biomarker Analysis
Imaging Biomarker Analysis
C64264
Diagnostic Imaging
CL369294
owl:Class
Diagnostic Procedure
Imaging Biomarker Analysis
Laboratory Procedure
C61035
C0202125
owl:Class
A quantitative measurement of the amount of magnesium present in a sample of serum.
Serum Magnesium Measurement
Serum Magnesium Measurement
Magnesium Measurement
Serum Magnesium Measurement
Serum Chemistry Measurement
Serum Magnesium Measurement
CL365177
Dental Percussion
Diagnostic Procedure
owl:Class
Dental Percussion
Dental Percussion
A diagnostic test performed on a tooth by tapping on the crown with a dental instrument.
Percussion
C62298
Dental Procedure
Dental Percussion
Light Exercise
Light Exercise
20-60 minutes of exercise which elevates your heart rate to 35-60% of your maximum heart rate performed at least 3-4 times per week.
Light exercises include housework, gardening, bowling, and slow walking. Maximum heart rate is approximately 220 minus current age in years.
C39771
CL323822
Exercise
Daily or Recreational Activity
Light Exercise
owl:Class
Light Activity
Light Exercise
Diagnostic Procedure
Endocervical Curettage
Endocervical Curettage
Endocervical Curettage
Endocervical Curettage
owl:Class
<def-source>NCI-GLOSS</def-source><def-definition>(en-do-SER-vih-kul kyoo-reh-TAHZH) The scraping of the mucous membrane of the cervical canal using a spoon-shaped instrument called a curette.</def-definition>
C15403
C0195344
endocervical curettage
Curettage Procedure
Tobacco Use Prevention Research
owl:Class
Tobacco Use Prevention Research
Tobacco Use Prevention Research
CL025585
Research Activity
C16211
Tobacco Use Prevention Research
Studies to develop and test interventions that are designed to prevent the initiation of tobacco use among individuals. (NCI/TRIP)
Smoking and Health Research
One Way ANOVA
One-way Analysis of Variance
One-way Analysis of Variance
Analysis of Variance
CL355781
One Way Analysis of Variance
One-way Analysis of Variance
owl:Class
One-way Analysis of Variance
One-way ANOVA
C53242
Quantitative Concept
Drop
Action
Leave undone or leave out; get rid of.
C48930
Drop
Drop
Drop
Dropping
Activity
owl:Class
Dropped
CL343751
owl:Class
Dissection
CL384811
Surgical Procedure by Method
Dissection
Dissection
C15227
The process of cutting apart or separating tissue as, for example, in the study of anatomy or in the course of a surgical procedure.
Diagnostic Procedure
Dissection
Therapeutic or Preventive Procedure
owl:Class
Quantitative Concept
Cluster Random Sampling
CL378123
Multi-Stage Cluster Random Sampling
C71501
Multi-Stage Cluster Random Sampling
Multi-Stage Sampling
Multi-Stage Cluster Random Sampling
Multi-Stage Cluster Random Sampling
C64224
MAS Probe Summary Method
Summarizes probe sets using the robust average 1-step Tukey biweight algorithm. Defined in the documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html
Activity
Bioconductor caAffy MAS Probe Summary Method
Bioconductor caAffy MAS Probe Summary Method
owl:Class
MAS
CL369376
Probe Summary Method
Bioconductor caAffy MAS Probe Summary Method
Bioconductor caAffy MAS Probe Summary Method
Left Radical Mastectomy
Radical Mastectomy
Left Radical Mastectomy
Left Radical Mastectomy
Left Radical Mastectomy
Therapeutic or Preventive Procedure
Procedure_Has_Completely_Excised_Anatomy only 'Left Breast'
CL354069
owl:Class
C51496
C0814048
Applied Research
owl:Class
Cytometry
Cytometry
The measurement of physical and /or chemical characteristics of cells, or, by extension, of other biological particles.
Cytometry
C25386
Cytometry
Research Activity
C74826
CDISC SDTM Laboratory Test Terminology by Name
Interleukin 29
owl:Class
Cytokine Measurement
CDISC SDTM Terminology
Interleukin 29 Measurement
Interleukin 29 Measurement
CL384307
Interleukin 29 Measurement
Interleukin 29 Measurement
<def-definition>A measurement of the interleukin 29 in a biological specimen.</def-definition><def-source>CDISC</def-source>
INTLK29
The determination of the amount of interleukin 29 present in a sample.
Laboratory Procedure
CDISC SEND Terminology
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Code
Lorazepam Measurement
owl:Class
C0524170
Lorazepam Measurement
C75374
Lorazepam Measurement
The determination of the amount of lorazepam present in a sample.
Laboratory Procedure
Lorazepam Measurement
Benzodiazepine Measurement
owl:Class
Repository Operation
Mixed Category Laboratory Procedure
Repository Operation
CL003782
Laboratory Procedure
Repository Operation
Repository Operation
C15977
CL342784
owl:Class
Collision-Induced Dissociation
Collision-Induced Dissociation
Collision-Induced Dissociation
Collision-Induced Dissociation
C48061
A method by which fragmentation can be achieved. CID is accomplished by selecting an ion of interest with the mass analyzer and then subjecting that ion to collisions with neutral atoms or molecules. The resulting fragment ions are then mass analyzed. (from The Expanding Role of Mass Spectrometry in Biotechnology by Gary Siuzdak)
Research Activity
CID
Physical Chemical Technique
Progression-free Survival
Survival
Progression-free Survival
progression-free survival
Progression-free Survival
C0242792
Progression-free Survival
PFS
C28234
Quantitative Concept
<def-source>NCI-GLOSS</def-source><def-definition>One type of measurement that can be used in a clinical study or trial to help determine whether a new treatment is effective. It refers to the probability that a patient will remain alive, without the disease getting worse.</def-definition>
owl:Class
Westfall Young Correction
CL378525
An adjustment method used in multiple comparison procedures to calculate an adjusted probability. This method ranks probabilities in descending order of their absolute p-values first, then calculate the adjusted p-values by an algorithm described in Dudoit et al. 2003.
Quantitative Concept
Multiple Comparison Adjustment
Westfall Young Adjustment
Westfall Young Adjustment
Westfall Young Adjustment
Westfall Young
Westfall Young Adjustment
C72514
owl:Class
Westfall Young Method
Research concerning any factor or condition, exposure to which is theoretically susceptible to behavioral modification, but in which no actual behavioral work is being done (e.g., experimental studies on tobacco use, consumption of various dietary components, and exposure to many other environmental carcinogens).
owl:Class
Research Activity
Behavior Research, Indirect
Behavior Research, Indirect
CL000089
Behavioral Research
Behavior Research, Indirect
C15771
Behavior Research, Indirect
Random Sampling
Systematic Sampling
Systematic Sampling
Systematic Sampling
Quantitative Concept
owl:Class
C53200
Systematic Sampling
CL356550
Procedure_Has_Completely_Excised_Anatomy only Nipple
Total Mastectomy
Mastectomy
Simple Mastectomy
Total Mastectomy
total mastectomy
Total Mastectomy
owl:Class
Procedure_Has_Completely_Excised_Anatomy only 'Mammary Gland'
Procedure_Has_Completely_Excised_Anatomy only Areola
Procedure_Has_Completely_Excised_Anatomy only Breast
<def-source>NCI-GLOSS</def-source><def-definition>(mas-TEK-toe-mee) Removal of the breast.</def-definition>
simple mastectomy
Total Mastectomy
Therapeutic or Preventive Procedure
Removal of only the breast tissue and nipple and a small portion of the overlying skin. (MeSH)
C0024886
C15281
Angiotensin II Measurement
Angiotensin II Measurement
C74845
Laboratory Procedure
owl:Class
<def-definition>A measurement of the angiotensin II hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Terminology
C0373546
CDISC SDTM Laboratory Test Terminology by Code
Angiotensin II Measurement
CDISC SDTM Laboratory Test Terminology by Name
The determination of the amount of angiotensin II hormone present in a sample.
ANGTNS2
Clinical Data Interchange Standards Consortium Terminology
Angiotensin II Measurement
CDISC SEND Terminology
Angiotensin II
Hormone Measurement
Coupling
Couple
Activity
C61302
CL025074
Coupled
Couple
The act of linking together.
Couple
Couple
Action
owl:Class
AIDS, Clinical Trials on Women
AIDS, Clinical Trials on Women
C15768
AIDS clinical trials related to females 12 years of age or older. These trials include pregnant women, women at risk of AIDS, female prostitutes, and women who have perinatally transmitted AIDS to a fetus or newborn.
CL000048
owl:Class
AIDS, Clinical Trials on Women
AIDS Clinical Trial
Research Activity
AIDS, Clinical Trials on Women
Fisher's Exact Test
Fisher's Test
Fisher's Exact Test
Fisher's Exact Test
Non-Parametric Test
Research Activity
owl:Class
A statistical test used to determine if there are nonrandom associations between two categorical variables. It is an alternative to the Chi-square test for small samples.
Fisher's Exact Test
CL335219
C45725
Dechallenge
Activity
Dechallenge
owl:Class
Action
C68620
Dechallenge
CL371885
The withdrawal of a medical intervention.
Dechallenge
<def-source>MSH2002_06_01</def-source><def-definition>A surgical technique used primarily in the treatment of skin neoplasms, especially basal cell or squamous cell carcinoma of the skin. This procedure is a microscopically controlled excision of cutaneous tumors either after fixation in vivo or after freezing the tissue. Serial examinations of fresh tissue specimens are most frequently done.</def-definition>
Therapeutic or Preventive Procedure
C28208
Mohs Surgery
<def-source>NCI-GLOSS</def-source><def-definition>A surgical technique used to treat skin cancer. Individual layers of cancerous tissue are removed and examined under a microscope one at a time until all cancerous tissue has been removed.</def-definition>
Mohs Surgery
owl:Class
Mohs Surgery
Mohs Surgery
Surgical Procedure by Method
C0079850
Mohs surgery
Prevention of Cervical Cancer
Cancer Prevention
Therapeutic or Preventive Procedure
Cervical Cancer Prevention
Prevention of Cervical Cancer
owl:Class
C15557
Prevention of Cervical Cancer
Prevention of Cervical Cancer
CL030499
Alternative Medical Procedure
Naturopathy Therapy
Naturopathic
C0027495
Naturopathy Therapy
Naturopathy
C15283
Naturopathy Therapy
Therapeutic or Preventive Procedure
owl:Class
A system of therapy based on preventative care, and on the use of heat, water, light, air, and massage as primary therapies for disease. Some naturopaths use no medications, either pharmaceutical or herbal. Some recommend herbal remedies only. A few who are licensed to prescribe may recommend pharmaceuticals in those cases where they feel their use is warranted. (MedicineNet.com)
<def-source>MSH2001</def-source><def-definition>A drugless system of therapy, making use of physical forces such as air, light, water, heat, massage, etc. Treatments are often diet- and nutrition-oriented with attention given to the patient's personal history and lifestyle. (From Cassileth, Alternative Medicine Handbook, 1998, p329)</def-definition>
Naturopathic Therapy
Naturopathy Therapy
CL355054
Dose Not Changed
Dose Not Changed
Dose Not Changed
CDISC SDTM Action Taken with Study Treatment Terminology
Action Taken with Study Treatment
C49504
<def-source>CDISC</def-source><def-definition>An indication that a medication schedule was continued without modification. (NCI)</def-definition>
Activity
An indication that a medication schedule was continued without modification.
Clinical Data Interchange Standards Consortium Terminology
Dose Not Changed
DOSE NOT CHANGED
owl:Class
CDISC SDTM Terminology
CDISC
owl:Class
Diagnostic Imaging
Digital Image Analysis
Diagnostic Procedure
Digital Image Analysis
C67525
Digital Image Analysis
Digital Image Analysis
CL372060
Instrumentation of the crown and root surfaces of a tooth to remove plaque and calculus from these surfaces. It is indicated for patients with periodontal disease and is therapeutic, not prophylactic, in nature. Root planing is the definitive procedure designed for the removal of cementum and dentin that is rough, and/or permeated by calculus or contaminated with toxins or microorganisms. Some soft tissue removal occurs. This procedure may be used as a definitive treatment in stages of periodontal disease and/or as a part of pre-surgical procedures in others.
Therapeutic or Preventive Procedure
C63714
owl:Class
Periodontal Treatment
Periodontal Scaling and Root Planing
Periodontal Scaling and Root Planing
Periodontal Scaling and Root Planing
Periodontal Scaling and Root Planing
CL366417
Screening for Cervical Cancer
Cervical Cancer Screening
Cancer Screening
Cervical Cancer Screening
Cervical Cancer Screening
Therapeutic or Preventive Procedure
CL030493
owl:Class
C15551
Cervical Cancer Screening
Cervical Cancer Early Detection
Early Detection of Cervical Cancer
Biopsy
C0193388
Liver Biopsy
Liver Biopsy
Procedure_Has_Partially_Excised_Anatomy only Liver
Removal of tissue from the liver for microscopic examination.
Biopsy of Liver
owl:Class
Liver Biopsy
Therapeutic or Preventive Procedure
Liver Biopsy
C51677
C81178
Newborn Screening
Newborn Screening
Diagnostic tests performed on neonates to assess overall health and identify potential areas of concern.
Age Appropriate Screening
Diagnostic Procedure
Newborn Assessment
Newborn Screening
Newborn Screening
owl:Class
owl:Class
Antimitochondrial Antibody Measurement
C81975
Antimitochondrial Antibody Measurement
Antimitochondrial Antibody Measurement
The determination of the amount of antimitochondrial antibodies present in a sample.
Antimitochondrial Antibody Measurement
Immunology Test
Burr Cell Count
CDISC SDTM Laboratory Test Terminology by Code
BURRCE
CDISC
Burr Cell Count
Burr Cells
Laboratory Procedure
Erythrocyte Count
<def-source>CDISC</def-source><def-definition>A measurement of the Burr cells (erythrocytes characterized by the presence of small, blunt projections evenly distributed across the cell surface) in a biological specimen.</def-definition>
C74701
CDISC SDTM Terminology
Keratocytes
Burr Cell Count
Clinical Data Interchange Standards Consortium Terminology
owl:Class
CL384690
Burr Cell Count
CDISC SEND Terminology
The determination of the number of Burr cells present in a sample.
CDISC SDTM Laboratory Test Terminology by Name
owl:Class
Central Pathology Review
CL378291
Activity
Central Pathology Review
The process by which specimens are sent to a central lab for confirmatory analysis using standardized methods and result criteria in order to minimize inter-reviewer differences thereby improving the accuracy of pathology data.
Central Pathology Review
C71684
Central Pathology Review
Review
Electrolyte Measurement
owl:Class
Chemistry Test
Electrolyte Measurement
Electrolyte Measurement
Electrolyte Measurement
Laboratory Procedure
A quantitative measurement of the amount of an electrolyte present in a sample.
C0201992
C74946
Nutritional Study
Role of dietary components in cancer causation or prevention and in general health.
Nutrition, Dietary Components
Nutrition, Dietary Components
Nutrition, Dietary Components
Nutrition, Dietary Components
owl:Class
CL000604
Research Activity
C15824
Verification
Supported or established by evidence or proof.
CL335035
Qualitative Concept
Verify
C45513
owl:Class
Verification
Verified
Action
Verification
Verification
INTLK12
Interleukin 12 Measurement
Interleukin 12 Measurement
The determination of the amount of interleukin 12 present in a sample.
CDISC SDTM Laboratory Test Terminology by Code
owl:Class
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Name
<def-definition>A measurement of the interleukin 12 in a biological specimen.</def-definition><def-source>CDISC</def-source>
Clinical Data Interchange Standards Consortium Terminology
Interleukin 12 Measurement
Cytokine Measurement
Interleukin 12 Measurement
CDISC SDTM Terminology
CL384289
CDISC SEND Terminology
C74808
Interleukin 12
Restriction Enzyme Analysis
CL005596
DNA Analysis
Restriction Enzyme Analysis
Laboratory Procedure
Diagnostic Procedure
owl:Class
C19581
Identification of restriction enzyme sites in DNA samples or DNA sequences.
Restriction Enzyme Analysis
Restriction Enzyme Analysis
Optical Methods
Any method of quantitative or qualitative analysis that involves optics and/or the measurement of light.
Optical Methods
Optical Methods
owl:Class
CL000650
Physical Chemical Technique
Optical Methods
Research Activity
C18912
Classification
Biopsy
Biopsy of Brain
C51766
Removal of brain tissue for microscopic examination.
Biopsy of Brain
Procedure_Has_Partially_Excised_Anatomy only Brain
Brain Biopsy
Biopsy of Brain
CL354991
Diagnostic Procedure
owl:Class
Biopsy of Brain
CDISC SDTM Laboratory Test Terminology by Code
C64801
Laboratory Procedure
Dacryocyte Analysis
Dacryocyte Analysis
CDISC SDTM Terminology
Clinical Data Interchange Standards Consortium Terminology
Dacryocytes
The determination of the presence or absence of dacryocytes, abnormal erythrocytes shaped like a teardrop, seen in myelofibrosis and certain other myeloproliferative diseases.
CDISC SEND Terminology
owl:Class
Tear Shaped Erythrocytes
TEARDCY
CDISC
CDISC SDTM Laboratory Test Terminology by Name
Hematology Test
CL370575
<def-definition>A measurement of dacryocytes per unit of a biological specimen.</def-definition><def-source>CDISC</def-source>
Dacryocyte Analysis
Dacryocyte Analysis
Cancer Prevention
Prevention of Esophageal Cancer
CL030501
Prevention of Esophageal Cancer
Esophageal Cancer Prevention
C15559
owl:Class
Therapeutic or Preventive Procedure
Prevention of Esophageal Cancer
Prevention of Esophageal Cancer
CL384291
Interleukin 14 Measurement
Interleukin 14 Measurement
<def-definition>A measurement of the interleukin 14 in a biological specimen.</def-definition><def-source>CDISC</def-source>
owl:Class
Clinical Data Interchange Standards Consortium Terminology
Laboratory Procedure
Interleukin 14 Measurement
CDISC SEND Terminology
C74810
Interleukin 14 Measurement
CDISC SDTM Laboratory Test Terminology by Code
INTLK14
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Terminology
Interleukin 14
Cytokine Measurement
The determination of the amount of interleukin 14 present in a sample.
owl:Class
Growth Factor Antagonist Therapy
CL029827
Therapeutic or Preventive Procedure
Growth Factor Antagonist Therapy
C15510
Growth Factor Antagonist Therapy
Immunotherapy
Growth Factor Antagonist Therapy
Diagnostic Procedure
owl:Class
CL378267
Cone-Beam Computed Tomography
C71695
Cone-Beam Computed Tomography
Cone-Beam Computed Tomography
Computed Tomography
Cone-Beam Computed Tomography
owl:Class
Thyroid Isthmectomy
Surgery involving excision of the isthmus of the thyroid gland.
Thyroidectomy
Thyroid Isthmectomy
CL354269
Procedure_Has_Completely_Excised_Anatomy only 'Thyroid Gland Isthmus'
C51737
Thyroid Isthmectomy
Thyroid Isthmectomy
Therapeutic or Preventive Procedure
Excision of Thyroid Isthmus
Tissue Culture
C0040284
Tissue Culture
owl:Class
Laboratory Procedure
C17201
Tissue Culture
Originally the maintenance and growth of pieces of explanted tissue (plant or animal) in culture away from the source organism. Now usually refers to the (much more frequently used) technique of cell culture, using cells dispersed from tissues or distant descendants of such cells.
Research Technique
Tissue Culture
Maintenance
Action
The act of sustaining something in its current form or proper condition; upkeep.
Maintenance
Instruction Imperative
Maintenance
Maintenance
Activity
C53297
Maintain
owl:Class
CL384831
C Reactive Protein
C64548
CRP
C-Reactive Protein Measurement
Laboratory Procedure
C0201657
C-Reactive Protein Measurement
A quantitative measurement of the amount of C-reactive protein present in a sample.
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Terminology
C-Reactive Protein Measurement
CDISC
Protein or Enzyme Type Measurement
CDISC SDTM Laboratory Test Terminology by Code
owl:Class
C-Reactive Protein Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the C reactive protein in a biological specimen.</def-definition>
CDISC SEND Terminology
Malignant Cell to Blood Cell Ratio Measurement
Laboratory Procedure
Blood Cell Count Ratio Measurement
Malignant Cell to Blood Cell Ratio Measurement
Clinical Data Interchange Standards Consortium Terminology
owl:Class
CDISC SDTM Laboratory Test Terminology by Name
The determination of the ratio of malignant cells compared to blood cells present in a sample. The measurement may be expressed as a ratio or percentage.
Malignant Cells, NOS/Blood Cells
CDISC SDTM Laboratory Test Terminology by Code
C74643
MLIGCEBC
CDISC SEND Terminology
CL384412
CDISC
Malignant Cell to Blood Cell Ratio Measurement
<def-source>CDISC</def-source><def-definition>A relative measurement (ratio or percentage) of the malignant cells of all types to all blood cells in a biological specimen.</def-definition>
CDISC SDTM Terminology
Malignant Cell to Blood Cell Ratio Measurement
Aspirate, Fine Needle
C1510483
Procedure_Has_Target_Anatomy only 'Body Fluid or Substance'
C15361
Needle Biopsy
Procedure_Has_Partially_Excised_Anatomy only Organ
Fine-Needle Aspiration
FNA
Diagnostic Procedure
Fine-Needle Aspiration
owl:Class
<def-source>NCI-GLOSS</def-source><def-definition>The removal of tissue or fluid with a needle for examination under a microscope.</def-definition>
Fine-Needle Aspiration
Fine Needle Aspiration
Fine-Needle Aspiration
fine-needle aspiration
Intracellular Fluorescence Polarization Analysis
Intracellular Fluorescence Polarization Analysis
C71319
Cellular Physiologic Testing
Intracellular Fluorescence Polarization Analysis
Laboratory Procedure
Intracellular Fluorescence Polarization Analysis
CL371843
owl:Class
Cancer Immunotherapy
Immunotoxin Cancer Immunotherapy
Immunotoxin Therapy
CL003749
Semisynthetic conjugates of various toxic molecules, including radioactive isotopes and bacterial or plant toxins, with specific immune substances such as immunoglobulins, monoclonal antibodies, and antigens. The antitumor or antiviral immune substance carries the toxin to the tumor or infected cell where the toxin exerts its poisonous effect.
Therapeutic or Preventive Procedure
Immunotoxin Cancer Immunotherapy
C15973
owl:Class
Immunotoxin Immunotherapy For Cancer
Immunotoxin Cancer Immunotherapy
Immunotoxin Cancer Immunotherapy
Immunotherapy, Cancer, Immunotoxin
C60720
Temporary Dental Restoration
Temporary Dental Restoration
Temporary Dental Restoration
C0011414
Reconstruction of a tooth or part of a tooth which is designed to seal the tooth and maintain its position until a permanent restoration is done.
Temporary Dental Restoration
owl:Class
Temporization
Therapeutic or Preventive Procedure
Dental Restoration
Quantitative Concept
Cluster Random Sampling
owl:Class
Random Sampling
C71493
Cluster Random Sampling
CL378103
Cluster Random Sampling
Cluster Random Sampling
C16438
Laboratory Procedure
Genetics, Gene Mapping
Molecular Biology Research Technique
Gene Mapping
Gene Localization
Molecular Genetic Technique
Gene Mapping
Gene Mapping
Molecular Analysis
Gene Mapping, Total Human and Non-Human
owl:Class
Genetic Mapping
Gene Mapping
C0008630
Determination of the relative positions of genes on a DNA molecule (chromosome or plasmid) and of the distance, in linkage units or physical units, between them.
Diagnostic Accuracy
Statistical Technique
Diagnostic Accuracy
C0598285
C41440
Diagnostic Accuracy
Tthe proportion of all the observations that have been classified correctly by the diagnostic procedures in given population, or using some diagnostic test, or by some medical institution or professional.
Accuracy of Diagnosis
owl:Class
Functional Concept
Diagnostic Accuracy
Leukocyte Therapy
CL030487
Leukocyte Therapy
C15545
Leukocyte Therapy
owl:Class
Adoptive Immunotherapy
Leukocyte Therapy
Therapeutic or Preventive Procedure
owl:Class
Enterostomy
Digestive System Surgery
Enterostomy
Ostomy
Enterostomy
Procedure_Has_Target_Anatomy only Intestine
Enterostomy
Surgical creation of an opening in the intestine.
C52005
C0014370
Therapeutic or Preventive Procedure
Multiple Imputation Technique
Quantitative Concept
Statistical Imputation
Multiple Imputation Technique
Multiple Imputation Technique
The substitution of missing data with the average derived from multiple datasets of data that is not missing.
owl:Class
C81202
Multiple Imputation Technique
<def-source>CDISC</def-source><def-definition>A measurement of the plasmacytoid lymphocytes (lymphocytes with peripherally clumped chromatin and often deep blue cytoplasm, and that appear similar to plasma cells) in a biological specimen.</def-definition>
CDISC
Plasmacytoid Lymphocyte Count
CDISC SDTM Laboratory Test Terminology by Name
owl:Class
C74618
The determination of the number of plasmacytoid lymphocytes present in a sample.
Laboratory Procedure
Plasmacytoid Lymphocytes
CDISC SEND Terminology
CL384712
Plasmacytoid Lymphocyte Count
Lymphocyte Count
LYMPL
Plasmacytoid Lymphocyte Count
Plasmacytoid Lymphocyte Count
Plymphocytes
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Terminology
Clinical Data Interchange Standards Consortium Terminology
Cardiac Therapeutic Procedure
Cardiac Therapeutic Procedure
C80430
Therapeutic or Preventive Procedure
Cardiac Therapeutic Procedure
owl:Class
A therapeutic procedure to treat pathologic or structural disorders of the heart.
Cardiac Therapeutic Procedure
Therapeutic Procedure
C19364
Health Education
Health Promotion and Education
Health Care Activity
Health Promotion and Education
Health Promotion and Education
Health Promotion and Education
owl:Class
C1272438
Cytological Procedure
Cytologic Technique
Technique or procedure for manipulation of cells and analysis of cell properties and subcellular features.
owl:Class
Cytology
Cytologic Procedure
Cytological Procedure
Anatomic Pathology Procedure
Cytological Procedure
Cytological Procedure
Laboratory Procedure
C0010818
C16490
Cytological Techniques
owl:Class
AIDS, Clinical Trials on Children
AIDS clinical trials related to children 0-18 years of age. These trials include pregnant females, neonates, and infants.
AIDS Clinical Trial
Research Activity
AIDS, Clinical Trials on Children
AIDS, Clinical Trials on Children
CL000047
AIDS, Clinical Trials on Children
C15767
A process whereby data is changed from one format to another.
Action
Activity
Data Transformation
C43582
Transformation
Data Transformation
A description of the transformation done to the data between the immediate source and the supplying source. May be as simple as transcription or involve a complicated transformation. (caBIO)
Data Transformation
CL333639
owl:Class
Data Transformation
A surgical procedure to place a stent within a vessel.
CL371838
owl:Class
Surgical Procedure
Therapeutic or Preventive Procedure
Stenting
Stenting
Stenting
C71316
Stenting
CDISC
C74743
CDISC SDTM Terminology
owl:Class
<def-source>CDISC</def-source><def-definition>A measurement of the N-telopeptide in a biological specimen.</def-definition>
N-Telopeptide Measurement
The determination of the amount of N-telopeptide present in a sample.
CDISC SEND Terminology
NTELOP
N-Telopeptide Measurement
Laboratory Procedure
N-telopeptide
CDISC SDTM Laboratory Test Terminology by Name
N-Telopeptide Measurement
C1868706
Clinical Data Interchange Standards Consortium Terminology
N-Telopeptide Measurement
Protein or Enzyme Type Measurement
CDISC SDTM Laboratory Test Terminology by Code
C15252
End of Life Care
Hospice Care
Health Care Activity
hospice
Hospice
Hospice Care
owl:Class
The active total care of patients whose disease is not responsive to curative treatment. The goal of palliative care is achievement of the best possible quality of life for patients and their families. Control of pain, of other symptoms, and of psychological, social, and spiritual problems is paramount. Palliative care affirms life and regards dying as a normal process, neither hastens nor postpones death, provides relief from pain and other distressing symptoms, integrates the psychological and spiritual aspects of patient care, offers a support system to help patients live as actively as possible until death, and offers a support system to help the family cope during the patient's illness and in their own bereavement. (World Health Organization)
<def-source>NCI-GLOSS</def-source><def-definition>(HOS-pis) A program that provides special care for people who are near the end of life and for their families, either at home, in freestanding facilities, or within hospitals.</def-definition>
Hospice Care
Hospice Care
C0085555
Palliative Therapy
owl:Class
Molecular Biology Research Technique
Propagation of an entire organism from somatic cell material. It was first accomplished in the 50's using frog embryonic tissues. In 1997 researchers in Scotland announced the cloning of a sheep, Dolly, using adult mammary cell DNA as the starting material. Since then several other species have been successfully cloned, including cows, mice, and monkeys.
Whole Organism Cloning
Whole Organism Cloning
CL001109
Cloning
C19126
Whole Organism Cloning
Whole Organism Cloning
Islet Cell 512 Antigen Measurement
Islet Cell 512 Antigen Measurement
Islet Cell 512 Antigen Measurement
Immunology Test
The determination of the amount of islet cell 512 antigen present in a sample.
C81986
owl:Class
Islet Cell 512 Antigen Measurement
Action
Activity
FDA
C73607
Relabel
Relabel
Relabel
Relabel
CL383662
Structured Product Labeling Business Operation Terminology
Relabelling
RELABEL
owl:Class
Diagnostic Procedure
Spectroscopy
ESR Spectroscopy
Spectroscopy, ESR
Spectroscopy, Electron Spin Resonance
Electron Spin Resonance Spectroscopy
Electron Spin Resonance
C0013845
Electron Spin Resonance Spectroscopy
<def-source>MSH2001</def-source><def-definition>A technique applicable to the wide variety of substances which exhibit paramagnetism because of the magnetic moments of unpaired electrons. The spectra are useful for detection and identification, for determination of electron structure, for study of interactions between molecules, and for measurement of nuclear spins and moments. (From McGraw-Hill Encyclopedia of Science and Technology, 7th edition) Electron nuclear double resonance (ENDOR) spectroscopy is a variant of the technique which can give enhanced resolution. Electron spin resonance analysis can now be used in vivo, including imaging applications such as MAGNETIC RESONANCE IMAGING.</def-definition>
owl:Class
ESR
Laboratory Procedure
Electron Spin Resonance Spectroscopy
Electron Paramagnetic Resonance
Electron Spin Resonance Spectroscopy
C16534
A spectrometric method, based on measurement of electron spins and magnetic moments, for detecting and estimating free radicals in reactions and in biological systems.
Research Activity
Randomized Controlled Clinical Trial
Randomized Controlled Clinical Trial
owl:Class
C0206035
A study in which the participants are assigned by chance to separate groups to evaluate treatments. The study also includes a control group, which is undergoing the same rigors of the study with placebo treatment or standard treatment. The trial can also be controlled by the addition of a test group to ensure there are no factors present to skew the results and by the inclusion of peer-review analysis by appropriate government officials. 2005
Randomized Controlled Clinical Trial
Randomized Clinical Trial
C46079
Randomized Controlled Clinical Trial
<def-source>CSP2000</def-source><def-definition>Research on a variety of aspects of diet, nutrition and cancer (e.g. the role of diet in preventing and treating cancer), or the effect of cancer on one's nutritional status; for the effect of diet as a factor or cause of cancer, use NUTRITION RELATED NEOPLASM/CANCER.</def-definition>
owl:Class
Cancer and Nutrition
C15658
Cancer and Nutrition
Cancer and Nutrition
Biomedical Occupation or Discipline
Cancer and Nutrition
Cancer Research
CL318180
Educational Activity
Science Enrichment
Science Enrichment
Science Enrichment
C19024
Patient or Public Education
owl:Class
CL000896
Science Enrichment
The addition of science courses or lectures to a school's or institution's curriculum.
Laboratory Procedure
owl:Class
The separation of specific cells or cell populations from a heterogeneous mixture. Specifically it refers to the selective retention of a population of desired cells through recognition of cells bearing the specified characteristics.
Positive Selection
Positive Selection
Positive Selection
CL377708
Mixed Category Laboratory Procedure
Positive Selection
C71257
Ileocolectomy
Therapeutic or Preventive Procedure
Ileocolectomy
Procedure_Has_Excised_Anatomy only Colon
Intestine Resection
Surgical removal of part or all of the ileum, and part or all of the colon.
CL355204
C51793
owl:Class
Ileocolectomy
Ileocolectomy
Procedure_Has_Excised_Anatomy only Ileum
Fractionation
<def-source>NCI-GLOSS</def-source><def-definition>Dividing the total dose of radiation therapy into several smaller, equal doses delivered over a period of several days.</def-definition>
Radiation Therapy
C0524811
C15654
owl:Class
fractionation
Fractionation
Therapeutic or Preventive Procedure
Fractionation
Fractionation Radiotherapy
Fractionation
Individual Behavior
owl:Class
Behavior
Stress and Coping
Use of conscious or unconscious strategies or mechanisms in adapting to stress.
Stress and Coping
Stress and Coping
C19382
CL004069
Stress and Coping
owl:Class
Incompatible Blood Transfusion
CL354658
Incompatible Blood Transfusion
Health Care Activity
Incompatible Blood Transfusion
C50832
Incompatible Blood Transfusion
Blood Transfusion
Therapeutic or Preventive Procedure
Surgery to remove part of the fallopian tube(s).
Partial Salpingectomy
Partial Salpingectomy
C51734
Salpingectomy
Procedure_Has_Partially_Excised_Anatomy only 'Fallopian Tube'
owl:Class
Partial Salpingectomy
CL353588
Partial Salpingectomy
owl:Class
Shotgun Sequencing
C19646
Shotgun Sequencing
Laboratory Procedure
Shotgun Sequencing
Large-Scale Sequencing
Molecular Biology Research Technique
Shotgun Sequencing
Unordered sequencing. Unmapped clones spanning a region of interest are sequenced and then assembled into a continuous sequence.
CL008156
Mature Plasma Cell to Lymphocyte Ratio Measurement
CDISC SDTM Laboratory Test Terminology by Code
PLSMCELY
The determination of the ratio of mature plasma cells compared to lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
Mature Plasma Cell to Lymphocyte Ratio Measurement
Blood Cell Count Ratio Measurement
<def-source>CDISC</def-source><def-definition>A relative measurement (ratio or percentage) of the mature plasma cells (plasmacytes) to all lymphocytes in a biological specimen.</def-definition>
owl:Class
Mature Plasma Cell to Lymphocyte Ratio Measurement
CDISC SEND Terminology
Laboratory Procedure
CL384327
C74911
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Terminology
CDISC
Mature Plasma Cell to Lymphocyte Ratio Measurement
Mature Plasma Cells/Lymphocytes
CDISC SDTM Laboratory Test Terminology by Name
intracavitary radiation
<def-source>NCI-GLOSS</def-source><def-definition>A radioactive source (implant) placed in a body cavity such as the chest cavity or the vagina.</def-definition>
Intracavitary Radiation Therapy
owl:Class
Intracavitary Radiation Therapy
Intracavitary Radiation
Intracavitary Radiation Therapy
C28049
CL054814
Intracavitary Radiation Therapy
Therapeutic or Preventive Procedure
Internal Radiation Therapy
C18674
Cancer Survivorship Research
Cancer Survivorship Research
CL000160
Cancer Control Research
Survivorship, Cancer
Activity
Cancer Survivorship Research
Cancer Survivorship
Research on cancer survivors, covers the full spectrum of biomedical and psycho-social issues that arise at the point of discontinuation of cancer-specific therapy to the point of terminal diagnosis (6 months or less to live).
Cancer Survivorship Research
owl:Class
Chemical Interference
Chemical Interference
CL004098
Chemical Interference
Molecular Biology Research Technique
C19397
DNA Footprinting
Chemical Interference
A type of footprinting technique used to define the location of protein-nucleic acid contacts at the base pair level in nucleic acids. It utilizes nucleic acids treated with a chemical in such a way that only a fraction of the nucleotides are chemically modified. The chemically modified nucleotides that interfere with protein-nucleic acid complex formation can be identified by fragmentation and electrophoretic analysis of the DNA isolated from the complexes.
owl:Class
In Vivo Imaging
C48799
Imaging Technique
In Vivo Imaging
In Vivo Imaging
owl:Class
CL342247
In Vivo Imaging
Laboratory Procedure
A microscopic visual representation of a biological component inside the body. The imaging procedure often utilizes a variety of diagnostic tools to provide insight regarding disease states, molecular characterization, and biological processes.
Imaging In Vivo
Diagnostic Procedure
Derivation
A drawing fluids from one part of the body to another, to relieve symptoms, reduce the inflammation or to otherwise lessen a morbid process.
CL337349
Derivation
Therapeutic or Preventive Procedure
owl:Class
C41378
Palliative Therapy
Derivation
Derivation
CDISC SDTM Laboratory Test Terminology by Code
Interleukin 18
CDISC SDTM Laboratory Test Terminology by Name
owl:Class
C74814
<def-definition>A measurement of the interleukin 18 in a biological specimen.</def-definition><def-source>CDISC</def-source>
Interleukin 18 Measurement
INTLK18
CL384295
CDISC SDTM Terminology
Interleukin 18 Measurement
Laboratory Procedure
Cytokine Measurement
Interleukin 18 Measurement
The determination of the amount of interleukin 18 present in a sample.
Interleukin 18 Measurement
CDISC SEND Terminology
Clinical Data Interchange Standards Consortium Terminology
Self-Examination
Self-Examination
Individual Behavior
C0080142
Self-Surveillance
Self-Examination
C15353
The inspection of one's own body, usually for signs of disease.
Self Care
owl:Class
Self-Examination
H2 Receptor Antagonist Therapy
CL031291
C15621
Receptor Antagonist Therapy
H2 Receptor Antagonist Therapy
H2 Receptor Antagonist Therapy
owl:Class
H2 Receptor Antagonist Therapy
Therapeutic or Preventive Procedure
Elective Surgical Procedure
Elective Surgical Procedure
Elective Surgical Procedure
Therapeutic or Preventive Procedure
Surgical Procedure
C51996
Elective Surgical Procedure
owl:Class
CL354531
The determination of the amount of beta-2 glycoprotein antibody present in a sample.
Beta-2 Glycoprotein Antibody Measurement
Immunology Test
C81979
Beta-2 Glycoprotein Antibody Measurement
Beta-2 Glycoprotein Antibody Measurement
owl:Class
Beta-2 Glycoprotein Antibody Measurement
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Code
C64481
CDISC SEND Terminology
<def-source>CDISC</def-source><def-definition>A measurement of the conjugated or water-soluble bilirubin in a biological specimen.</def-definition>
owl:Class
Direct Bilirubin Measurement
CDISC
Laboratory Procedure
CDISC SDTM Terminology
The bilirubin is bound to glucuronide to form conjugated bilirubin (direct bilirubin). Direct Bilirubin measurement is accomplished by a colorimetric method. Direct Bilirubin in biological fluids reacts with sulfanilic acid at acidic pH to produce a red colored complex. The optical density of produced color has a direct relationship with Direct Bilirubin concentration in the solution.
Direct Bilirubin Measurement
Direct Bilirubin
BILDIR
C0697273
CDISC SDTM Laboratory Test Terminology by Name
Liver Function Test
Direct Bilirubin Measurement
Direct Bilirubin Measurement
Perioperative Adjuvant Therapy
C16031
Treatment given at the time of an operation to augment the effects of the operation.
owl:Class
Perioperative Adjuvant Therapy
CL004803
Adjuvant Therapy
Perioperative Adjuvant Therapy
Therapeutic or Preventive Procedure
Perioperative Adjuvant Therapy
Microetching
C52577
CL356490
A method of roughening the surface of a natural tooth or a dental restoration, most likely the inside of a metal crown or the facial side of a metal crown to prepare it for repair, utilizing a gas-impelled jet of a fine abrasive. It enhances the attachment of resin cements or restorative materials to the surface.
Microetching
Microetching
owl:Class
Therapeutic or Preventive Procedure
Dental Procedure
Microetching
Bowel Preparation
Bowel Preparation
owl:Class
C62659
Bowel Preparation
Therapeutic or Preventive Procedure
Purging and cleansing of fecal and other matter from the bowel to assure subsequent clear evaluation of the bowel or to limit complications due to accidental surgical bowel perforation.
Bowel Preparation
C0455052
Pre-Procedure Preparation
Coordinating
Coordination
C25462
Action
Coordinated
Coordination
The act of bringing into common action, movement, or condition.
Qualitative Concept
Coordination
owl:Class
C0700114
Coordination
CL353543
Conceptual Entity
Moderate-Dose
Moderate-Dose Treatment
Therapeutic Procedure
owl:Class
Moderate-Dose Treatment
C49342
Moderate-Dose Treatment
The regular strength or dosage quantity of a therapeutic agent prescribed to be taken at one time or at stated intervals.
Moderate-Dose Treatment
5a-Reductase Inhibition
5a-Reductase Inhibition
Antiandrogen Therapy
Therapeutic or Preventive Procedure
5a-Reductase Inhibition
CL030177
C15526
Treatment with a 5a-reductase inhibitor with the goal of suppressing the conversion of testosterone to dihydrotestosterone.
5a-Reductase Inhibition
owl:Class
Phenomenon or Process
Instruction Imperative
CL375908
owl:Class
Subtraction
Subtraction
C70590
Subtract
CL024350
Action
Subtraction
The act of removing a part from the whole.
Activity
Subtraction
Biopsy of Larynx
Diagnostic Procedure
C51663
Biopsy of Larynx
Procedure_Has_Partially_Excised_Anatomy only Larynx
Biopsy of Larynx
Removal of tissue from the larynx for microscopic examination.
Biopsy of Larynx
Biopsy
CL354441
Laryngeal Biopsy
owl:Class
owl:Class
[Therapeutic implications] Research in radiotherapy using ionizing and non-ionizing radiation and those areas in radiobiology and radiation physics that relate to radiation therapy, including laboratory investigations at the molecular, cellular, tissue, and whole animal levels. (DEA-CAACT)
Radiotherapy Research
Radiotherapy Research
C16049
CL007016
Radiotherapy Research
Research Activity
Applied Research
Radiation
Radiotherapy Research
owl:Class
The determination of the amount of beta amyloid present in a sample.
C81999
Beta Amyloid Measurement
Beta Amyloid Measurement
Protein or Enzyme Type Measurement
Beta Amyloid Measurement
Beta Amyloid Measurement
Therapeutic or Preventive Procedure
C0282614
Acupressure Therapy
<def-source>NCI-GLOSS</def-source><def-definition>The application of pressure or localized massage to specific sites on the body to control symptoms such as pain or nausea. Also used to stop bleeding.</def-definition>
The application of non-invasive finger pressure along energy points throughout the body in order to relieve pain and induce a feeling of well-being.
Alternative Medical Procedure
Ischemic Compression
owl:Class
Acupressure Therapy
Acupressure Therapy
C15606
Acupressure Therapy
Acupressure
acupressure
Thoracentesis
C15392
<def-source>NCI-GLOSS</def-source><def-definition>(thor-a-sen-TEE-sis) Removal of fluid from the pleural cavity through a needle inserted between the ribs.</def-definition>
owl:Class
Pleural Tap
Thoracentesis
Procedure_Has_Target_Anatomy only 'Thoracic Cavity'
Pleural Cavity Tap
Chest Aspiration
Diagnostic Procedure
Therapeutic or Preventive Procedure
thoracentesis
Paracentesis
Thoracentesis
Puncture of Pleural Cavity for Aspiration
Thoracic Surgical Procedure
Thoracentesis
C0189477
Thoracic Paracentesis
Pleurocentesis
C82006
The determination of the amount of CD40 present in a sample.
CD40 Measurement
owl:Class
CD40 Measurement
CD40 Measurement
Protein or Enzyme Type Measurement
CD40 Measurement
caBIO
Research Activity
Cancer Bioinformatics Infrastructure Object Model
Cancer Bioinformatics Infrastructure Objects
Cancer Bioinformatics Infrastructure Objects
owl:Class
C42878
CL333280
Cancer Bioinformatics Infrastructure Objects
Cancer Bioinformatics Infrastructure Objects
The vision for caCORE is to provide a common data management framework that will support the consistency, clarity, and comparability of biomedical research data and information. The cancer Bioinformatics Infrastructure Objects (caBIO) model and architecture is the primary programmatic interface to caCORE. The heart of caBIO is its domain objects, each of which represents an entity found in biomedical research. These domain objects are related to each other, and examining these relationships can bring to the surface biomedical knowledge that was previously buried in the various primary data sources.
Cancer Research
Incomplete Ovariectomy
Incomplete Oophorectomy
Incomplete Oophorectomy
Incomplete Oophorectomy
Incomplete Oophorectomy
Procedure_Has_Partially_Excised_Anatomy only Ovary
Surgery that does not remove the entire ovary. This can be by design or by error.
CL320064
C29893
Therapeutic or Preventive Procedure
Oophorectomy
Ovariectomy, Incomplete
owl:Class
Nutrition, Food and Water Contaminants
C15437
Research Activity
Nutrition, Dietary Components
Nutrition, Food and Water Contaminants
CL108501
Role of food and water contaminants in cancer causation or prevention and in general health.
owl:Class
Nutrition, Food and Water Contaminants
Nutrition, Food and Water Contaminants
owl:Class
Number of Prior Chemotherapies
Number of prior chemotherapy regimens: If a patient has received a chemotherapy regimen, provide the number of different single or multi agent chemotherapy regimens the patient has received. A regimen is described as a distinctive collection of agent(s) and/or modalities to be utilized together during a cycle or course of therapy. A chemotherapy regimen may have been discontinued for any reason (e.g. completion of therapy, toxicity, disease progression). If the planned treatment is ABVD/MOPP code as one chemotherapy regimen.
Multiple Agents Therapy
C16159
Clinical Attribute
Prior Chemotherapy
Number of Prior Chemotherapies
Number of Prior Chemotherapies
CL014349
Number of Prior Chemotherapies
Blood Platelet Transfusion
The infusion of platelets into the bloodstream.
Platelet Transfusion
<def-source>MSH2001</def-source><def-definition>The transfer of blood platelets from a donor to a recipient or reinfusion to the donor.</def-definition>
Therapeutic or Preventive Procedure
C0086818
Platelet Transfusion
owl:Class
Platelet Transfusion
C15366
Blood Transfusion
Platelet Transfusion
C0553989
Excisional Biopsy of Lymph Node
Excisional Biopsy of Lymph Node
Excisional Biopsy of Lymph Node
Lymph Node Biopsy
A surgical procedure in which a single or multiple lypmph nodes are removed for microscopic examination.
owl:Class
Excisional Biopsy
Diagnostic Procedure
Lymph Node Excision
Excisional Biopsy of Lymph Node
C51662
Role of Vitamin B, its precursons, and its analogs in cancer causation or prevention and in general health.
Nutrition, Vitamin B
Nutrition, Vitamin B
C15927
Research Activity
CL102260
Nutrition, Vitamins
Nutrition, Vitamin B
Nutrition, Vitamin B
owl:Class
Shampoo
owl:Class
The act of washing hair with a cleaning agent.
Shampoo
Shampoo
Activity
Shampoo
C1554936
Wash
C65097
Therapeutic or Preventive Procedure
owl:Class
Therapeutic Bronchoscopy
Therapeutic Bronchoscopy
CL370551
Therapeutic Endoscopic Procedure
Therapeutic Bronchoscopy
Therapeutic Bronchoscopy
Bronchoscopy
C64971
Preoperative Endocrine Therapy
CL017736
Short term endocrine therapy, prior to surgery, to "down-stage" primary breast cancer in order to increase the rate of breast-conserving surgery. (from JMCC 7:557-562, 2000 via Medscape)
Therapeutic or Preventive Procedure
Preoperative Endocrine Therapy
owl:Class
Endocrine Drug Therapy
C16194
Preoperative Endocrine Therapy
Preoperative Endocrine Therapy
Estrogen Receptor Negative
Estrogen Receptor Negative
Estrogen Receptor Status
Negative Estrogen Receptor
<def-source>NCI-GLOSS</def-source><def-definition>Breast cancer cells that do not have a protein (receptor molecule) to which estrogen will attach. Breast cancer cells that are ER- do not need the hormone estrogen to grow and usually do not respond to hormone (antiestrogen) therapy that blocks these receptor sites.</def-definition>
C0279756
Estrogen Receptor Negative
owl:Class
Clinical Attribute
estrogen receptor negative
C15493
Estrogen Receptor Negative
ER-
Dilation
Dilation
The act of expanding an aperture.
Activity
C62252
Dilation
Action
C0012356
Dilation
owl:Class
owl:Class
Eligibility Criteria for Clinical Trials
Clinical Trial Eligibility Criteria
CL008804
Clinical Trial Eligibility Criteria
Study Eligibility Criteria
Clinical Trials Design
Clinical Trial Eligibility Criteria
Characteristics which are necessary to allow a subject to participate in a clinical study, as outlined in the study protocol. The concept covers inclusion and exclusion criteria.
Clinical Trial Eligibility Criteria
Research Activity
C16112
Trial Eligibility Criteria
Head and Neck Cancer Prevention
Prevention of Head and Neck Cancer
CL030497
C15555
Cancer Prevention
Prevention of Head and Neck Cancer
Prevention of Head and Neck Cancer
owl:Class
Therapeutic or Preventive Procedure
Prevention of Head and Neck Cancer
Mass Spectrometry
C0599748
Laboratory Procedure
owl:Class
Tandem Mass Spectrometry
MS/MS
Tandem Mass Spectrometry
C18142
Tandem Mass Spectrometry
Tandem Mass Spectrometry
Mass spectrometers coupled in series. The targeted compound is selectively ionized, and its characteristic ions are separated from others in the mixture in the first mass spectrometer. The selected primary ions are then decomposed by collision, and from the resulting products the final mass analyzer selects secondary ions characteristic of the targeted compound. Tandem mass spectrometry can achieve specificities and sensitivities equivalent of those of methods such as radioimmunoassay and gas chromatography/mass spectrometry, while performing analyses in much shorter times.
Laboratory Procedure
Passage
Removal of a cell culture from the culture vessel with a subculture (passage) process, in order to keep the cells at a sufficiently low density to stimulate further growth.
Passage
CL357721
C54573
owl:Class
Passage
Passage
Tissue Culture
Mean
Measure of Central Tendency
C0444504
Quantitative Concept
Clinical Data Interchange Standards Consortium Glossary Terminology
<def-source>CDISC</def-source><def-definition>The sum of the values of all observations or data points divided by the number of observations; an arithmetical average.</def-definition>
Mean
CDISC
C53319
mean
Mean
Statistical Mean
Mean
owl:Class
The sum of a set of values divided by the number of values in the set.
CDISC SDTM Laboratory Test Terminology by Name
Precursor Plasma Cell to Lymphocyte Ratio Measurement
Precursor Plasma Cell to Lymphocyte Ratio Measurement
Precursor Plasma Cell to Lymphocyte Ratio Measurement
CL384336
CDISC SEND Terminology
The determination of the ratio of precursor plasma cells compared to all lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
Clinical Data Interchange Standards Consortium Terminology
PLSPCELY
C74650
CDISC
Laboratory Procedure
CDISC SDTM Terminology
Precursor Plasma Cells/Lymphocytes
Precursor Plasma Cell to Lymphocyte Ratio Measurement
<def-source>CDISC</def-source><def-definition>A relative measurement (ratio or percentage) of the precursor (blast stage) plasma cells (antibody secreting cells derived from B cells via antigen stimulation) to all lymphocytes in a biological specimen.</def-definition>
owl:Class
Blood Cell Count Ratio Measurement
CDISC SDTM Laboratory Test Terminology by Code
Therapeutic Touch
Biofield Therapy
Healing Touch
An energy (biofield) therapy that encompasses a group of non-invasive techniques that utilize the hands to clear, energize, and balance the human and environmental energy fields. Healing Touch interventions may be used to restore, energize, and balance an energy field disturbance. (HTA)
Therapeutic Touch
Therapeutic Touch
owl:Class
C0150386
Therapeutic Touch
C15373
Therapeutic or Preventive Procedure
owl:Class
Infusion Procedure
Donor Cellular Infusion
CL386891
C77273
A form of adoptive immunotherapy used after hematopoietic stem cell transplantation (HSCT). Lymphocytes from the original stem cell donor are given to the HSCT recipient, after the transplant, to augment an antitumor immune response (graft-versus-tumor), or ensure that the donor stem cells remain engrafted. Although lymphocytes are the most commonly used cell, other cells including fibroblasts, mesenchymal or dendritic cells may be delivered to affect chimerism, treat Graft vs. Host Disease, treat viral infections or Post Transplant Lymphoproliferative Disease or other novel uses under investigation.
Therapeutic or Preventive Procedure
Donor Cellular Infusion
Donor Cellular Infusion
Donor Cellular Infusion
<def-definition>A measurement of the codeine present in a biological specimen.</def-definition><def-source>CDISC</def-source>
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Terminology
Codeine Measurement
Codeine Measurement
Codeine
owl:Class
C74877
Opioid Measurement
Codeine Measurement
Codeine Measurement
CDISC SDTM Laboratory Test Terminology by Code
Laboratory Procedure
CODEINE
The determination of the amount of codeine present in a sample.
CDISC SEND Terminology
C0524087
CDISC SDTM Laboratory Test Terminology by Name
Humidification-Modulated Radiation Therapy
Humidification-Modulated Radiation Therapy
Humidification-Modulated Radiation Therapy
Therapeutic or Preventive Procedure
C71752
Radiation Therapy
CL378277
Humidification-Modulated Radiation Therapy
owl:Class
Sperm Banking
Supportive Care
C0037840
<def-source>MSH2001</def-source><def-definition>Centers for acquiring and storing semen.</def-definition>
Sperm Banking
Sperm Banking
owl:Class
sperm banking
C15326
Health Care Activity
<def-source>NCI-GLOSS</def-source><def-definition>Freezing sperm for use in the future. This procedure can allow men to father children after loss of fertility.</def-definition>
Sperm Banking
Hemoglobin A to Total Hemoglobin Ratio Measurement
Hemoglobin Measurement
Hemoglobin A to Total Hemoglobin Ratio Measurement
owl:Class
Newborn Screening
Hemoglobin A to Total Hemoglobin Ratio Measurement
Percent Hemoglobin A
Hemoglobin A to Total Hemoglobin Ratio Measurement
The determination of the ratio of Hemoglobin A compared to total Hemoglobin present in a sample. The measurement may be expressed as a ratio or percentage.
Laboratory Procedure
C81276
C46089
Allogeneic Hematopoietic Stem Cell Transplantation
HSC
HSCT
CL341893
Allogeneic Hematopoietic Stem Cell Transplantation
owl:Class
Therapeutic or Preventive Procedure
Allogeneic Hematopoietic Stem Cell Transplantation
Hematopoietic Stem Cell Transplantation
A clinical treatment in which hematopoietic stem cells (HSCs) are transferred from one genetically dissimilar individual to another.
Allogeneic Hematopoietic Stem Cell Transplantation
C0394477
C21023
owl:Class
Electroanalgesia
SCS
Therapeutic or Preventive Procedure
A highly invasive form of electroanalgesia used to treat various chronic pain syndromes, which resist treatment by more common means. It is also used to treat peripheral ischemia, peripheral vascular disease, complex regional pain syndrome, intractable angina, chronic mesenteric ischemia, and diabetic peripheral arterial occlusive disease. (from White, Li, and Chiu)
Spinal Cord Stimulation
Spinal Cord Stimulation
Spinal Cord Stimulation
Spinal Cord Stimulation
<def-source>CDISC</def-source><def-definition>A study of the biochemical and physiological effect of a drug and the mechanism of drug action and the relationship between drug concentration and effect. (NCI)</def-definition>
Pharmacodynamic Study
CDISC
Clinical Data Interchange Standards Consortium Terminology
Research Activity
owl:Class
Pharmacodynamic Study
A study of the biochemical and physiological effect of a drug and the mechanism of drug action and the relationship between drug concentration and effect.
C49662
Pharmacodynamic Study
CDISC SDTM Trial Type Terminology
PHARMACODYNAMIC
Pharmacodynamic Study
Human Pharmacology Study
CL354154
CDISC SDTM Terminology
Convenience Sampling
owl:Class
Convenience Sampling
Volunteer Sample
Nonrandom Sampling
Convenience Sampling
C53204
Convenience Sampling
Quantitative Concept
C0150095
owl:Class
Continuous Distribution
Log-Normal Distribution
C53224
Log Normal Distribution
CL355739
Quantitative Concept
Lognormal Distribution
Log Normal Distribution
The single-tailed probability distribution of any random variable whose logarithm is normally distributed.
Log Normal Distribution
Log Normal Distribution
esophagectomy
Esophagectomy
<def-source>NCI-GLOSS</def-source><def-definition>(eh-sof-a-JEK-toe-mee) An operation to remove a portion of the esophagus.</def-definition>
excision of the esophagus
Therapeutic or Preventive Procedure
Digestive System Surgery
Esophagectomy
Esophagectomy
owl:Class
C0085198
Surgical removal of part or all of the esophagus.
C15357
Procedure_Has_Excised_Anatomy only Esophagus
Esophagectomy
Transmission Electron Microscopy
Laboratory Procedure
Transmission Electron Microscopy
Transmission Electron Microscopy
Microscopy, Electron, Transmission
<def-source>CSP2000</def-source><def-definition>original electron microscopic technique; the photographic imaging of a sample created by a beam of electrons passing through a thin section; resolution ranges from macromolecular to cellular.</def-definition>
Transmission Electron Microscopy
An electron microscopy imaging technique that is utilized to examine structural components of a sample by passing electrons through the specimen.
C0678118
owl:Class
TEM
C18216
Electron Microscopy
Immunization
immunization
<def-source>NCI-GLOSS</def-source><def-definition>A technique used to cause an immune response that results in resistance to a specific disease, especially an infectious disease.</def-definition>
Primary Prevention
C1368825
Therapeutic or Preventive Procedure
C15258
Immunization
Immunization
Immunization
<def-source>MSH2001</def-source><def-definition>Deliberate stimulation of the host's immune response. Active immunization involves administration of antigens or immunologic adjuvants. Passive immunization involves administration of immune sera or lymphocytes or their extracts (e.g., transfer factor, immune RNA) or transplantation of immunocompetent cell producing tissue (thymus or bone marrow).</def-definition>
owl:Class
Routine
Routine
C47893
An unvarying or habitual method or procedure.
Routine
Action
C0205547
Activity
Routine
owl:Class
The determination of the amount of any beta-blocker present in a sample.
owl:Class
Beta-Blocker Measurement
Laboratory Procedure
CL384466
Beta-Blocker Measurement
Beta-Blocker Measurement
Beta-Blocker Measurement
C75383
Drug Class Measurement
Therapeutic or Preventive Procedure
Surgical removal of the transverse colon.
Transverse Colectomy
Transverse Colectomy
Partial Colectomy
Procedure_Has_Excised_Anatomy only 'Transverse Colon'
CL354846
owl:Class
Transverse Colectomy
Transverse Colectomy
C51612
Academic Detailing
Educational Activity
Academic Detailing
Academic Detailing
C20054
An approach to educating physicians in their offices. It uses relatively inexpensive, focused educational mechanisms that can be used during short one-on-one conversations with physicians.
CL014974
Academic Detailing
Educational Activity
owl:Class
Research Activity
Interdisciplinary Studies
Multidisciplinary Research
Interdisciplinary Research
Multidisciplinary Collaboration
Interdisciplinary Research
Interdisciplinary Research
Research Activity
Interdisciplinary Research
owl:Class
C15428
Multidisciplinary
Studies that bring together multiple scientific disciplines to address specific issues.
C0242479
C15846
Radiation Ionizing Radiotherapy
Radiation Ionizing Radiotherapy
Therapeutic or Preventive Procedure
Radiation Ionizing Radiotherapy
CL000810
Radiation
Local Therapy
Radiation Therapy
Radiation Ionizing Radiotherapy
The use of ionizing radiation to kill cancer cells
owl:Class
C51763
CL353594
Percutaneous Needle Biopsy
Percutaneous Needle Biopsy
owl:Class
Percutaneous Needle Biopsy
Diagnostic Procedure
Needle Biopsy
Percutaneous Needle Biopsy
Surgical Procedure by Method
Therapeutic or Preventive Procedure
C0524865
C25351
Supportive Care
Reconstruction
Reconstruction
Reconstruction
reconstructive surgery
Reconstruction
<def-source>NCI-GLOSS</def-source><def-definition>Surgery that is done to reshape or rebuild (reconstruct) a part of the body changed by previous surgery.</def-definition>
owl:Class
Reconstructive Surgery
Surgical restoration of function or form of a part.
Cocaine Measurement
Cocaine Measurement
CNS Stimulant Drug Measurement
CDISC SDTM Laboratory Test Terminology by Code
C74690
Clinical Data Interchange Standards Consortium Terminology
Cocaine Measurement
C0202362
CDISC SDTM Laboratory Test Terminology by Name
The determination of the amount of cocaine present in a sample.
owl:Class
Laboratory Procedure
Cocaine
COCAINE
CDISC
CDISC SDTM Terminology
Cocaine Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the cocaine present in a biological specimen.</def-definition>
CDISC SEND Terminology
Light-Scattering Spectroscopy
owl:Class
Light-Scattering Spectroscopy
Light-Scattering Spectroscopy
Spectroscopy
Light-Scattering Spectroscopy
Laboratory Procedure
The nuclei of precancerous lesions are distinct in that they become enlarged, crowded and hyperchromatic. Light-scattering spectroscopy can diagnose early epithelial cancers based on the scattering of light through their enlarged nuclei. (from Medscape)
CL015001
C20059
Diagnostic Procedure
Epidemiological Method
Epidemiological Method
C0014503
Epidemiological Method
Epidemiology, Method
Epidemiological Method
Epidemiological Technique
C16555
Research Technique
Epidemiological methods involve sophisticated statistics and higher mathematics. These methods allow epidemiologists to address issues like non-experimental studies of mechanistic questions in disease etiology, including studies of the impact of the social position of individuals in different social contexts.
owl:Class
Research Activity
The use of any device, marker, or other means for the purpose of detecting the presence of disease, usually in asymptomatic individuals.
C15419
<def-source>NCI-GLOSS</def-source><def-definition>Checking for disease when there may be no symptoms the individual being screened is aware of.</def-definition>
Disease Screening
Screening Intervention
Diagnostic Procedure
Disease Screening
Disease Screening
Disease Screening Procedure
owl:Class
Screening
C0220908
Intervention or Procedure
Disease Screening
C80179
Complement C5a Measurement
Laboratory Procedure
Complement C5a Measurement
Complement C5a Measurement
owl:Class
The determination of the amount of complement C5a present in a sample.
Complement C5a Measurement
Complement Measurement
PSI
C16198
Research Activity
Research Activity
Protein Structure Initiative
A NIGMS initiative to define the basic protein shapes and to catalog all proteins in terms of these shapes. This project will require the determination of a large number (perhaps 10,000) of protein structures in a high throughput mode. (from RFA: GM-99-009)
CL018642
Protein Structure Initiative
Protein Structure Initiative
Protein Structure Initiative
owl:Class
Individual Case Safety Report Terminology
FDA
Remedial Action
Modification or Adjustment
Modification or Adjustment
CL357561
Modification or Adjustment
Type Of Remedial Action ICSR Terminology
owl:Class
C53606
Modification or Adjustment
Occupational Activity
NCI Initiative to integrate the cytogenetic and physical maps of the human genome, generate a repository of BAC clones arrayed across the genetic and physical map, and to develop a publicly available database displaying this clone repository and providing a platform for correlation with other databases of chromosomal aberrations, as well as clinical and histopathological information.
C1516184
Cancer Genome Anatomy Project
Cancer Chromosome Aberration Project
Cancer Chromosome Aberration Project
Cancer Chromosome Aberration Project (CCAP)
Cancer Chromosome Aberration Project
CCAP
Cancer Chromosome Aberration Project
Research Activity
C15939
owl:Class
C51599
owl:Class
CL354507
Duodenectomy
Partial Small Intestine Resection
Surgical removal of part or all of the duodenum.
Procedure_Has_Excised_Anatomy only Duodenum
Duodenectomy
Duodenectomy
Therapeutic or Preventive Procedure
Duodenectomy
Suicide Gene Therapy
Suicide Gene Therapy
Suicide Gene Therapy
owl:Class
C16115
CL008892
Suicide Gene Therapy
Therapeutic or Preventive Procedure
Gene Therapy
Oxandrolone Measurement
C0524219
Oxandrolone Measurement
The determination of the amount of oxandrolone present in a sample.
Steroid Measurement
Laboratory Procedure
owl:Class
C75381
Oxandrolone Measurement
Oxandrolone Measurement
Activity
Do Not Swallow
owl:Class
Do Not Swallow
Instruction Imperative
Do Not Swallow
C0566357
C65122
Do Not Swallow
Clinical Data Interchange Standards Consortium Terminology
Estrone Measurement
<def-definition>A measurement of the estrone hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
owl:Class
Estrone
Hormone Measurement
Laboratory Procedure
Estrone Measurement
Estrone Measurement
CDISC SDTM Laboratory Test Terminology by Code
Oestrone
The determination of the amount of estrone hormone present in a sample.
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Name
ESTRONE
CDISC SEND Terminology
Estrone Measurement
C0236379
C74857
Eotaxin-3 Measurement
C81954
Eotaxin-3 Measurement
owl:Class
Eotaxin-3 Measurement
The determination of the amount of eotaxin-3 present in a sample.
Chemokine Measurement
Eotaxin-3 Measurement
Basic Research
Basic Science Research
Basic Science Research
Research Activity
Fundamental research designed to obtain or increase general scientific knowledge, performed without the goal of developing a direct application intended to solve a specific problem.
C15714
Basic Science Research
Research Activity
Basic Science Research
Basic Science
owl:Class
C0681833
CL004305
C16008
Cooperative Group Program
Cooperative Group Program
Cancer Research
Cooperative Group Program
owl:Class
NCI-sponsored program that promotes and supports clinical trials in cancer treatment, (largely combined modality approaches); cancer prevention, and early detection within setting of a Cooperative Group.
Cooperative Group Program
Governmental or Regulatory Activity
Protein Tyrosine Kinase Inhibitor Therapy
C62721
Therapeutic or Preventive Procedure
Protein Tyrosine Kinase Inhibitor Therapy
Protein Tyrosine Kinase Inhibitor Therapy
Enzyme Inhibitor Therapy
CL034867
owl:Class
Protein Tyrosine Kinase Inhibitor Therapy
Alaryngeal Speech
owl:Class
Alaryngeal Voice Production
Alaryngeal Speech
Alaryngeal Speech
Training
C0037833
Health Care Activity
C17159
Alaryngeal Speech
Instructional activity designed to teach patients how to vocalize with a non-functioning or absent larynx.
ESI
Electrospray Ionization
owl:Class
Electrospray Ionization
Laboratory Procedure
A procedure used in mass spectrometry analysis. Means of delivering nonvolatile analytes into the gas phase for mass analysis. Best used on molecules which are charged in solution or readily accept a charge. Particularly well suited to the analysis of biomolecules. Can be used to probe tertiary structure and non-covalent interactions (from NCSU Mass Spectrometry Facility web site)
C1516801
C19363
Electrospray Ionization
Research Technique
Electrospray Ionization
C53249
Quantitative Concept
Correlation Test
Non-Parametric Test
owl:Class
Spearman Correlation Test
Spearman Correlation Test
Spearman Correlation Test
CL356366
Spearman Correlation Test
Spearman Correlation
Caesarian Section
Gynecological Surgical Procedure
owl:Class
Therapeutic or Preventive Procedure
Procedure_Has_Target_Anatomy only 'Corpus Uteri'
C46088
C-Section
The delivery of an infant through a surgical abdominal incision. Surgery is performed when there may be complications associated with a vaginal birth and increased risk to the mother or fetus.
Caesarian Section
Caesarian Section
Abdominal Delivery
C0007876
Cesarian Section
Newborn Screening
Caesarian Section
C0008562
Laboratory Procedure
owl:Class
C16434
Frequently referred to simply as HPLC, this form of column chromatography is used frequently in biochemistry. The analyte is forced through a column by liquid at high pressure, which decreases the time the separated components remain on the stationary phase. Less time on the column then translates to narrower peaks in the resulting chromatogram and thence to better selectivity and sensitivity.
Liquid Chromatography
High Performance Liquid Chromatography
High Performance Liquid Chromatography
High Performance Liquid Chromatography
High Performance Liquid Chromatography
HPLC
<def-source>MSH2001</def-source><def-definition>Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.</def-definition>
Computation
Computation
owl:Class
Computational
CL364074
Activity
C61298
Action
Computed
Computation
The act of calculating; determining something by mathematical or logical methods.
Computation
Computing
Structured Product Labeling Business Operation Terminology
API Manufacture
owl:Class
C82401
API Manufacture
API Manufacture
API MANUFACTURE
Active Pharmaceutical Ingredients Manufacturing
The act of producing active pharmaceutical ingredients from raw materials.
Activity
FDA
Action
API Manufacture
Hematology Test
Erythrocyte Mean Corpuscular Volume
CDISC
C0863148
owl:Class
Ery. Mean Corpuscular Volume
The mean cell volume is the average volume of a red blood cell. This is a calculated value derived from the hematocrit and the red cell count.
Erythrocyte Mean Corpuscular Volume
MCV
Erythrocyte Mean Corpuscular Volume
CDISC SEND Terminology
Clinical Data Interchange Standards Consortium Terminology
<def-source>CDISC</def-source><def-definition>A quantitative measurement of the mean volume of erythrocytes in a biological specimen.</def-definition>
CDISC SDTM Laboratory Test Terminology by Code
C64799
Laboratory Procedure
Erythrocyte Mean Corpuscular Volume
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Terminology
Laboratory Procedure
C61025
owl:Class
Gamma Glutamyl Transpeptidase Measurement
CL364120
Serum Gamma Glutamyl Transpeptidase Measurement
A quantitative measurement of the amount of gamma glutamyl transpeptidase present in a sample of serum.
Serum Chemistry Measurement
Serum Gamma Glutamyl Transpeptidase Measurement
Serum Gamma Glutamyl Transpeptidase Measurement
Serum Gamma Glutamyl Transpeptidase Measurement
C73926
Activity
Delegate
Delegate Action
To entrust to another.
Delegated
Delegate Action
Delegate Action
CL383912
Action
Delegate Action
owl:Class
Develop and evaluate new laboratory assays, behavioral methods, and statistical techniques for epidemiologic studies. (FMB)
Technique Development
Technique Development
CL001228
Research Activity
Research Activity
C15894
owl:Class
Technique Development
Technique Development
Informational Intervention
C0541653
Chart Review
Medical Chart Review
Health Care Activity
Medical Chart Review
owl:Class
C64254
Medical Chart Review
Medical Chart Review
Quantitative Concept
Statistical Imputation
owl:Class
C81206
The substitution of missing data with the worst value observed in a group of subjects.
Worst Observed Value in a Group Imputation Technique
Worst Observed Value in a Group Imputation Technique
Worst Observed Value in a Group Imputation Technique
Worst Observed Value in a Group Imputation Technique
Tobacco Use
owl:Class
Tobacco Use
Tobacco Consumption
C0543414
Personal Behavior
Tobacco Use
Tobacco Use
C18059
Use of tobacco in any form i.e. smoking, chewing or sniffing.
Individual Behavior
Therapeutic or Preventive Procedure
Orthodontic Treatment
Dental Distalization
Movement of teeth in a posterior direction.
Dental Distalization
Dental Distalization
Dental Distalization
C82129
owl:Class
owl:Class
Activity
CL334864
C45257
The process of increasing by addition (as to a collection or group).
Accession
Action
Accession
Accession
Accession
Point Estimation
Research Activity
The process of using sample data to determine a single best value for a population parameter.
Point Estimation
Statistical Estimation
Point Estimation
C53330
CL355783
owl:Class
Point Estimation
Managed Care
Managed Care
Managed Care
An arrangement whereby a third-party payer (e.g., insurance company, federal government, or corporation) mediates between physicians and patients, negotiating fees for service and overseeing the types of treatment given. Managed care has virtually replaced unmanaged indemnity plans, where payment is automatic and oversight procedures are minimal. Whereas 96% of American workers had unmanaged indemnity in 1984, only 28% did in 1988. Typically, in managed care, the third-party payer requires second opinions and pre-certification review for patients requiring hospital admission. They obtain wholesale prices from doctors, and carry out cost-containment measures, including auditing hospitals and reviewing claims. Managed care has figured heavily in the national debate over health care.
C0086583
Health Care Activity
C15364
owl:Class
Patient Care
Managed Care
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
Blood Cell Count Ratio Measurement
CDISC SEND Terminology
PRLYMLE
CDISC SDTM Laboratory Test Terminology by Code
Prolymphocyte to Leukocyte Ratio
Prolymphocyte to Leukocyte Ratio
CDISC
The determination of the ratio of prolymphocytes compared to leukocytes in a blood sample. The measurement may be expressed as a ratio or percentage.
Prolymphocyte to Leukocyte Ratio
CL370341
<def-definition>A relative measurement (ratio or percentage) of prolymphocytes to leukocytes in a biological specimen.</def-definition><def-source>CDISC</def-source>
C64829
owl:Class
Prolymphocyte to Leukocyte Ratio
Prolymphocytes/Leukocytes
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Terminology
Internal Radiation Brachytherapy
Selective Internal Radiation Therapy
owl:Class
Selective Internal Radiation Therapy
C71591
Selective Internal Radiation Therapy
Selective Internal Radiation Therapy
Therapeutic or Preventive Procedure
CL371830
Nutrition, Vitamin C
Research Activity
Nutrition, Vitamin C
Nutrition, Vitamin C
Nutrition, Vitamins
Role of Vitamin C, its precursons, and its analogs in cancer causation or prevention and in general health.
Nutrition, Vitamin C
owl:Class
C15928
CL102259
Bone Spectrometry
owl:Class
Bone Spectrometry
C38039
CL322406
Spectrometry
Bone Spectrometry
Laboratory Procedure
Bone Spectrometry
Spectrometry used to determine aspects of bone composition.
Testosterone Measurement
Steroid Measurement
Testosterone Measurement
The determination of the amount of testosterone present in a sample.
Laboratory Procedure
Testosterone Measurement
owl:Class
Testosterone Measurement
C0523912
C75378
owl:Class
Manufacturing Product Defect Manufacturing Defect Both Safety And LOEE
Manufacturing Product Defect Manufacturing Defect Both Safety And LOEE
Intellectual Product
Regulatory Assessment
MANUFACTURING/PRODUCT DEFECT MANUFACTURING DEFECT (BOTH SAFETY AND LOEE)
C82457
Manufacturing Product Defect Manufacturing Defect Both Safety And LOEE
Manufacturing Product Defect Manufacturing Defect Both Safety And LOEE
CKMM
CDISC SDTM Laboratory Test Terminology by Code
Creatine Kinase MM Measurement
Creatine Kinase Measurement
CDISC SDTM Terminology
CDISC SEND Terminology
CL045203
Creatine Kinase MM Measurement
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Name
<def-source>CDISC</def-source><def-definition>A measurement of the homozygous M-type creatine kinase in a biological specimen.</def-definition>
CDISC
owl:Class
Creatine Kinase MM Measurement
C64494
A quantitative measurement of the amount of homozygous M-type creatine kinase present in a sample.
Creatine Kinase MM
Creatine Kinase MM Measurement
Clinical Data Interchange Standards Consortium Terminology
Scatter in a mass or jet of droplets.
Spray
CL370617
Spray
Activity
owl:Class
Spray
Instruction Imperative
Spray
C65101
Muscle Biopsy
Procedure_Has_Partially_Excised_Anatomy only Muscle
Removal of tissue from the muscle, for microscopic examination.
Biopsy
Muscle Biopsy
C51895
C0185283
Muscle Biopsy
Biopsy of Muscle
owl:Class
Muscle Biopsy
Diagnostic Procedure
Risk-Adjusted Incidence Rate
Risk-Adjusted Incidence Rate
C53353
Quantitative Concept
owl:Class
Risk-Adjusted Incidence Rate
Incidence Rate
CL356729
Risk-Adjusted Incidence Rate
owl:Class
The technique whereby chromosomes are exchanged among cells.
Genetic Technique
C18698
Chromosome Transfer
Molecular Biology Research Technique
Chromosome Transfer
Chromosome Transfer
CL000213
Chromosome Transfer
Infusion Technique
owl:Class
CL102847
Infusion Technique
Functional Concept
Infusion Technique
Infusion Technique
C21087
Infusion Procedure
C0018823
Procedure_Has_Completely_Excised_Anatomy only Heart
Therapeutic or Preventive Procedure
Cardiac Transplantation
A surgical procedure in which a damaged heart is removed and replaced by another heart from a suitable donor. It is performed in patients with end-stage heart failure or severe coronary artery disease.
Cardiovascular Surgical Procedure
Organ Transplantation
C15246
Heart Transplantation
Cardiac Therapeutic Procedure
Heart Grafting
Heart Transplantation
owl:Class
Heart Transplantation
Heart Transplantation
Caffeine Measurement
CNS Stimulant Drug Measurement
Caffeine Measurement
Caffeine Measurement
The determination of the amount of caffeine present in a sample.
C0202348
Caffeine Measurement
Laboratory Procedure
owl:Class
C75346
Activity
C70775
CL375943
Brownian Dynamics
Simulations used to describe the motion of molecules in solution, generally discounting the effects of inertia.
owl:Class
Brownian Dynamics
Brownian Dynamics
Brownian Dynamics
Molecular Dynamics
Patient or Public Education
C0018701
Health Education
Health Education
owl:Class
Educational Activity
Health Education
C16664
<def-source>MSH2001</def-source><def-definition>Education that increases the awareness and favorably influences the attitudes and knowledge relating to the improvement of health on a personal or community basis.</def-definition>
Health Education
owl:Class
Intrathecal Chemotherapy
Therapeutic or Preventive Procedure
Intrathecal Chemotherapy
Intrathecal Chemotherapy
CL032320
C15750
Compartmental Treatment
Regional Chemotherapy
<def-source>NCI-GLOSS</def-source><def-definition>(in-tra-THEE-kal KEE-mo-THER-a-pee) Anticancer drugs that are injected into the fluid-filled space between the thin layers of tissue that cover the brain and spinal cord.</def-definition>
intrathecal chemotherapy
Intrathecal Chemotherapy
Quantitative Concept
Limited Duration Prevalence
C53366
owl:Class
Limited Duration Prevalence
Limited Duration Prevalence
Population-Based Statistic
Limited Duration Prevalence
CL356292
C15515
Cytokine Therapy
CL029948
Colony-Stimulating Factor Therapy
Colony-Stimulating Factor Therapy
Therapeutic or Preventive Procedure
owl:Class
Colony-Stimulating Factor Therapy
Colony-Stimulating Factor Therapy
Prevention of Bladder Cancer
C15735
Cancer Prevention
Prevention of Bladder Cancer
CL032160
owl:Class
Prevention of Bladder Cancer
Prevention of Bladder Cancer
Therapeutic or Preventive Procedure
in vitro Treated Peripheral Blood Lymphocyte Therapy
Therapeutic or Preventive Procedure
Peripheral Blood Lymphocyte Therapy
in vitro Treated Peripheral Blood Lymphocyte Therapy
C66900
owl:Class
CL371346
in vitro Treated Peripheral Blood Lymphocyte Therapy
in vitro Treated Peripheral Blood Lymphocyte Therapy
Child Health Study
CL354474
Maternal and Child Health Study
owl:Class
Child Health Study
Child Health Study
Child Health Study
Research Activity
C15203
Tonsillectomy
C51679
Tonsillectomy
Tonsillectomy
CL354277
Head and Neck Surgery
Surgical removal of the tonsils.
Tonsillectomy
Therapeutic or Preventive Procedure
owl:Class
Procedure_Has_Excised_Anatomy only Tonsil
The act of ending one's own life.
owl:Class
Personal Behavior
Suicide
Suicide
C0038661
Suicide
C3394
Individual Behavior
Suicide
Diagnostic Aspiration
C65005
Ultrasonic Surgical Aspiration
Diagnostic Ultrasonic Surgical Aspiration
Diagnostic Ultrasonic Surgical Aspiration
CL370150
owl:Class
Diagnostic Procedure
Diagnostic Ultrasonic Surgical Aspiration
Diagnostic Ultrasonic Surgical Aspiration
Proinsulin Measurement
C81967
Hormone Measurement
Proinsulin Measurement
The determination of the amount of proinsulin present in a sample.
Proinsulin Measurement
owl:Class
Proinsulin Measurement
C49134
Suspension
CL355528
owl:Class
Suspension
Action
Activity
Suspension
Suspension
To stop a process by imposing a freeze on it.
C62722
Intratumoral Therapy
Intratumoral Therapy
Intratumoral Therapy
Therapeutic or Preventive Procedure
Therapeutic Procedure
Intratumoral Therapy
owl:Class
CL365366
owl:Class
MICROCY
Microcyte Count
The determination of the number of microcytes in a blood sample.
<def-definition>A measurement of the microcytes per unit of a biological specimen.</def-definition><def-source>CDISC</def-source>
Clinical Data Interchange Standards Consortium Terminology
Microcytes
Erythrocyte Count
CDISC
CL370576
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Terminology
Microcyte Count
CDISC SEND Terminology
Microcyte Count
Microcyte Count
Laboratory Procedure
C64822
Therapeutic or Preventive Procedure
Ventricular Assist Device Placement
Cardiovascular Surgical Procedure
Ventricular Assist Device Placement
Ventricular Assist Device Placement
C80452
Ventricular Assist Device Placement
owl:Class
A surgical procedure in which a mechanical pump is implanted to enhance the function of the left or right heart ventricle.
Repacking
FDA
C73606
REPACK
Repack
Action
Activity
owl:Class
CL383663
Repack
Repack
Structured Product Labeling Business Operation Terminology
Repack
Graft-Versus-Tumor Induction Therapy
Graft-Versus-Tumor Induction Therapy
C63339
Graft-Versus-Tumor Induction Therapy
Therapeutic or Preventive Procedure
Vaccine Therapy
owl:Class
CL365356
Graft-Versus-Tumor Induction Therapy
Compliance Monitoring
Compliance Monitoring
C62737
owl:Class
Health Care Activity
Compliance Monitoring
Behavioral Intervention
Therapeutic or Preventive Procedure
CL365549
Compliance Monitoring
Therapy
Therapeutic or Preventive Procedure
Therapeutic Interventions
Therapeutic Procedure
Therapeutic Technique
Therapeutic Method
An action or administration of therapeutic agents to produce an effect that is intended to alter or stop a pathologic process.
Intervention or Procedure
C49236
therapy
TX
owl:Class
Therapeutic Procedure
Treatment
C0087111
Therapeutic Procedure
Therapeutic Procedure
Restriction Enzyme Mapping
Restriction Enzyme Analysis
Use of restriction endonucleases to generate a physical map of genomes, genes, or other segments of DNA.
C17094
Laboratory Procedure
owl:Class
Restriction Enzyme Mapping
Restriction Enzyme Mapping
C0035269
Restriction Enzyme Mapping
owl:Class
Subtotal Parathyroidectomy
C51594
Subtotal Parathyroidectomy
Procedure_Has_Partially_Excised_Anatomy only 'Parathyroid Gland'
CL355520
Therapeutic or Preventive Procedure
Subtotal Parathyroidectomy
Parathyroidectomy
Subtotal Parathyroidectomy
Partial excision of the parathyroid gland(s).
implant radiation
Brachytherapy
<def-source>NCI-GLOSS</def-source><def-definition>(ray-dee-AY-shun) A procedure in which radioactive material sealed in needles, seeds, wires, or catheters is placed directly into or near a tumor. Also called brachytherapy, internal radiation, or interstitial radiation.</def-definition>
Radiation Brachytherapy
Radiation Brachytherapy
Implant Radiation
Therapeutic or Preventive Procedure
Local Therapy
Radiation Therapy
Radiation Brachytherapy
owl:Class
C15195
C0006098
Radiation Brachytherapy
Renin Measurement
Renin Measurement
RENIN
CDISC SDTM Terminology
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Name
Renin
Protein or Enzyme Type Measurement
Renin Measurement
CDISC SDTM Laboratory Test Terminology by Code
C0373719
C74893
Laboratory Procedure
owl:Class
<def-definition>A measurement of the renin in a biological specimen.</def-definition><def-source>CDISC</def-source>
The determination of the amount of renin present in a sample.
Clinical Data Interchange Standards Consortium Terminology
Renin Measurement
Angiotensinogenase
C48678
Preclinical Study
<def-source>CDISC</def-source><def-definition>Animal studies that support Phase 1 safety and tolerance studies and must comply with good laboratory practice (GLP). NOTE: Data about a drug's activities and effects in animals help establish boundaries for safe use of the drug in subsequent human testing (clinical studies or trials).</def-definition>
Research Activity
CDISC
Clinical Data Interchange Standards Consortium Glossary Terminology
Clinical Data Interchange Standards Consortium Terminology
owl:Class
Preclinical Study
Study
Preclinical Study
CL054598
preclinical studies
<def-source>NCI-GLOSS</def-source><def-definition>Research using animals to find out if a drug, procedure, or treatment is likely to be useful. Preclinical studies take place before any testing in humans is done.</def-definition>
A study to test a drug, procedure or other medical treatment in animals. The aim is to collect data in support of safety. Preclinical studies are required before clinical trials can be started.
preclinical study
Preclinical Study
Screening Study
Screening Study
Screening Study
Clinical studies testing the efficacy of devices, techniques, procedures, or tests for the purpose of detecting the presence of disease, usually before there are any symptoms.
CL378149
C71485
Screening Study
Research Activity
Research Activity
owl:Class
Screening Trial
Alpha-1 Antitrypsin Measurement
Alpha-1 Antitrypsin Measurement
owl:Class
C80167
Alpha-1 Antitrypsin Measurement
Protein or Enzyme Type Measurement
The determination of the amount of alpha-1 antitrypsin present in a sample.
Alpha-1 Antitrypsin Measurement
Laboratory Procedure
Trial Phase 2
Phase II Trial
Clinical Study by Phase
CDISC SDTM Trial Phase Terminology
Phase II Trial
2
Phase 2 Study
C0282460
Phase II Study
Clinical Trials, Phase II
C15601
Phase II Trial
CDISC
Research Activity
<def-source>NCI-GLOSS</def-source><def-definition>A study to test whether a new treatment has an anticancer effect (for example, whether it shrinks a tumor or improves blood test results) and whether it works against a certain type of cancer.</def-definition>
Phase II Clinical Trial
A clinical research protocol designed to study a biomedical or behavioral intervention in a larger group of people (several hundred), to evaluate the drug's effectiveness for a particular indication in patients with the disease or condition under study, and to determine the common short-term side effects and risks associated with the intervention.
<def-source>CDISC</def-source><def-definition>Phase 2. Controlled clinical studies conducted to evaluate the effectiveness of the drug for a particular indication or indications in patients with the disease or condition under study and to determine the common short-term side effects and risks associated with the drug. NOTE: Phase 2 studies are typically well controlled, closely monitored, and conducted in a relatively small number of patients, usually involving no more than several hundred subjects. [After FDA CDER Handbook, ICH E8] (CDISC glossary)</def-definition>
Phase II Trial
owl:Class
phase II trial
Phase II Protocol
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Terminology
Pain Management Method
Therapeutic or Preventive Procedure
Distraction
CL008706
Distraction
Distraction
distraction
C5330
Distraction and Attention
<def-source>NCI-GLOSS</def-source><def-definition>In medicine, a pain relief method that takes the patient's attention away from the pain.</def-definition>
owl:Class
Distraction
A method of pain control used primarily in pediatrics that combines distracting the patient's attention away from the painful procedure or circumstance.
C53243
Two-way Analysis of Variance
Analysis of Variance
Quantitative Concept
Two-way Analysis of Variance
Two-way Analysis of Variance
Two-way ANOVA
Two-way Analysis of Variance
Two Way ANOVA
CL356374
Two Way Analysis of Variance
owl:Class
C15725
Laparoscopic Surgery
Laparoscopic Surgery
Therapeutic or Preventive Procedure
Laparoscopic Surgery
Laparoscopic Surgery
laparoscopy-assisted surgery
owl:Class
C0751429
Surgical Procedure by Method
Diagnostic Procedure
Biopsy of Small Intestine
Biopsy of Jejunum
owl:Class
Removal of tissue from the jujunum for microscopic examination, using an endoscope.
Jejunal Biopsy
C51902
CL354994
Biopsy of Jejunum
Procedure_Has_Partially_Excised_Anatomy only Jejunum
Diagnostic Procedure
Biopsy of Jejunum
Biopsy of Jejunum
Procollagen Type I Carboxy Terminal Peptide Measurement
Procollagen Type I Carboxy Terminal Peptide Measurement
Protein or Enzyme Type Measurement
owl:Class
The determination of the amount of procollagen type I carboxy terminal peptide present in a sample.
Procollagen Type I Carboxy Terminal Peptide Measurement
Procollagen Type I Carboxy Terminal Peptide Measurement
C82033
The prevention of conception or impregnation by the use of devices or drugs or surgery.
Personal Behavior
C37932
Contraception
Health Care Activity
Contraception
owl:Class
Contraception
Contraception
C0700589
C63338
owl:Class
Recombinant Viral Vaccine Therapy
Recombinant Viral Vaccine Therapy
Recombinant Viral Vaccine Therapy
Biological Therapy
CL365807
Recombinant Viral Vaccine Therapy
Therapeutic or Preventive Procedure
Screening for Ovarian Cancer
ovarian cancer screening
Screening for Ovarian Cancer
early detection of ovarian cancer
C15576
CL030732
Cancer Screening
Screening for Ovarian Cancer
Screening for Ovarian Cancer
Diagnostic Procedure
ovarian cancer early detection
owl:Class
Magnetoencephalography
Magnetoencephalography
MEG
owl:Class
C0024489
Magnetoencephalography
The measurement of the magnetic fields produced by electrical activity in the brain, usually conducted externally, using extremely sensitive devices. The measurement of electric fields in the brain provides information about the localization of brain activity which is complementary to that provided by electroencephalography.
Magnetoencephalography
Diagnostic Procedure
C16811
Imaging Technique
HUMARA Assay
HUMARA Analysis
HUMARA Assay
Diagnostic Procedure
HUMARA Assay
HUMARA Assay
Human androgen receptor gene assay. This assay was used to detect X chromosomal inactivation for diagnosis of X-linked conditions, ie. Kennedy disease, agammaglobulinemia, and others.
Hormone Receptor Test
owl:Class
Human Androgen Receptor Gene Assay
Laboratory Procedure
HUMARA
C18305
CL032125
Partial Omentectomy
Partial Omentectomy
owl:Class
Partial Omentectomy
Omentectomy
CL353586
Partial resection of the omentum.
C51788
Partial Resection of Omentum
Partial Omentectomy
Procedure_Has_Partially_Excised_Anatomy only Omentum
Therapeutic or Preventive Procedure
Vaccine Development
Vaccine Design and Animal Testing
Vaccine Design and Animal Testing
owl:Class
C15865
Health Care Activity
CL001066
Vaccine Design and Animal Testing
Vaccine Design and Animal Testing
Apply findings from basic, epidemiologic, and clinical research to the design and evaluation of vaccine strategies in laboratory studies and animal models, and foster collaboration with industry in the research and development of candidate vaccines.
owl:Class
Partial Parotidectomy
Partial Parotidectomy
Partial Parotidectomy
CL353587
Partial Parotidectomy
Parotidectomy
Therapeutic or Preventive Procedure
Procedure_Has_Partially_Excised_Anatomy only 'Parotid Gland'
Surgery involving partial excision of the parotid gland.
C51573
Non-Parametric Test
In statistical inference procedures (hypothesis tests and confidence intervals), nonparametric procedures are those that are relatively free of assumptions about population parameters.
owl:Class
Non-Parametric Test
Statistical Test
CL356331
C53229
Quantitative Concept
Nonparametric Test
Non-Parametric Test
Non-Parametric Test
Complete Excision
Therapeutic or Preventive Procedure
owl:Class
CL353825
Complete Excision
Complete Excision
Total Resection
C51934
Complete Excision
Excision
Pharmacotherapy
Pharmacotherapy
Pharmacological Treatment
Pharmacologic Management
Therapeutic or Preventive Procedure
C15986
Pharmacotherapy
Pharmacological Treatments
Treatment With Medication
Pharmacotherapy
owl:Class
CL100340
Treatment of disease through the use of drugs.
Cytokine Therapy
CL029166
C15469
Interferon Therapy
Therapeutic or Preventive Procedure
Interferon Therapy
Interferon Therapy
Interferon Therapy
owl:Class
C80197
Matrix Metalloproteinase 9 Measurement
Matrix Metalloproteinase 9 Measurement
The determination of the amount of matrix metalloproteinase 9 present in a sample.
Matrix Metalloproteinase 9 Measurement
Protein or Enzyme Type Measurement
owl:Class
Matrix Metalloproteinase 9 Measurement
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Code
C79466
<def-definition>A relative measurement (ratio or percentage) of the BB-type creatine kinase to total creatine kinase in a biological specimen.</def-definition><def-source>CDISC</def-source>
CKBBCK
Creatine Kinase BB to Total Creatine Kinase Ratio Measurement
CDISC SDTM Terminology
Urine Protein Measurement
Creatine Kinase BB to Total Creatine Kinase Ratio Measurement
Clinical Data Interchange Standards Consortium Terminology
The determination of the ratio of creatine kinase BB compared to total creatine kinase present in a sample. The measurement may be expressed as a ratio or percentage.
Creatine Kinase BB to Total Creatine Kinase Ratio Measurement
Creatine Kinase BB to Total Creatine Kinase Ratio Measurement
Laboratory Procedure
Creatine Kinase BB/Total Creatine Kinase
owl:Class
Discrete Distributions
Discrete Distribution
Statistical Distribution
A statistical distribution whose elements may only assume discreet values.
Discrete Distribution
CL356258
Discrete Distribution
C53207
owl:Class
Quantitative Concept
Discrete Distribution
Protein/Amino Acid Nutrition, Non-Animal
Protein/Amino Acid Nutrition, Non-Animal
Research Activity
Study of dietary non-animal protein/amino acids in relation to cancer.
CL000788
Protein/Amino Acid Nutrition, Non-Animal
owl:Class
Nutrition, Protein/Amino Acids
Protein/Amino Acid Nutrition, Non-Animal
C15845
C15826
Nutritional Study
Nutritional Anthropometry
CL000607
The study of nutritional effects upon the size, weight, and proportions of the human body.
Research Activity
Nutritional Anthropometry
Nutritional Anthropometry
Nutritional Anthropometry
owl:Class
Therapeutic or Preventive Procedure
owl:Class
Therapeutic Procedure
C0203597
Hyperthermia Treatment
Hyperthermia Treatment
<def-source>NCI-GLOSS</def-source><def-definition>(hye-per-THER-mee-a) A type of treatment in which body tissue is exposed to high temperatures to damage and kill cancer cells or to make cancer cells more sensitive to the effects of radiation and certain anticancer drugs.</def-definition>
C15415
Hyperthermia Treatment
Hyperthermia Treatment
Removal of tissue from the esophagus for microscopic examination, using an endoscope.
Esophageal Biopsy
Endoscopic Biopsy
Biopsy of Esophagus
Esophageal Biopsy
Esophageal Biopsy
owl:Class
Diagnostic Procedure
CL354550
C51686
Procedure_Has_Partially_Excised_Anatomy only Esophagus
Esophageal Biopsy
C0418967
Other Therapy
Other Therapy
C15645
Therapeutic Procedure
Therapeutic or Preventive Procedure
Other Therapy
Other Therapy
owl:Class
C80193
Laboratory Procedure
Matrix Metalloproteinase 2 Measurement
Matrix Metalloproteinase 2 Measurement
Matrix Metalloproteinase 2 Measurement
The determination of the amount of matrix metalloproteinase 2 present in a sample.
Matrix Metalloproteinase 2 Measurement
owl:Class
Protein or Enzyme Type Measurement
Read
C48222
Read
owl:Class
Activity
Read
Action
C0034754
The act of interpreting something that is written or printed.
Instruction Imperative
Read
C17755
Toxicity Testing
owl:Class
Toxicity Test
Toxicity Test
C0242890
Toxicity Test
Controlled laboratory tests to determine the toxicity of a chemical to an organism in terms of specific chemical concentrations.
Chemistry Test
Toxicity Test
Laboratory Procedure
Nanoimprint
Nanoimprinting
A lithographic technique that is used to transfer the topographic patterns of a master (often called the mold or template) to a resistant material or other surface through direct contact or pressing. UV radiation or heat is usually applied to make the transferred patterns permanent.
Nanoimprinting
C62315
Nanoimprinting
Non-Clinical Nanoparticle Application
Nanoimprinting
Activity
CL364918
owl:Class
C15581
Intraperitoneal Therapy
Intraperitoneal Chemotherapy
owl:Class
Intraperitoneal Chemotherapy
Regional Chemotherapy
CL030796
Intraperitoneal Chemotherapy
The administration of pharmaceutical agents directly into the abdominal or peritoneal cavity. This technique is widely utilized for the chemotherapeutic treatment of advanced ovarian cancer.
Therapeutic or Preventive Procedure
Intraperitoneal Chemotherapy
Photometry
Photometry
Occupational Activity
C65109
Photometry
Research Technique
C0031752
Photometry
Measurement of the properties of light, especially luminous intensity.
Photometric
owl:Class
Breeding
Activity
owl:Class
Breeding
Breeding
C0006159
Action
C42877
The production of animals or plants by selective pairing.
Breeding
Nanoparticle Characterization
Nanoparticle Characterization
Physical Chemical Technique
Activity
Nanoparticle Characterization
CL364924
Nanoparticle Characterization
A series of analytical methods that provide information about nanoscale entities such as composition, structure and defects. This information is critical for nanoparticle preparation, the study of properties, use, and reproducibility of the material.
owl:Class
C62317
Cytokine Measurement
CDISC SDTM Laboratory Test Terminology by Name
INTLK31
Interleukin 31 Measurement
<def-definition>A measurement of the interleukin 31 in a biological specimen.</def-definition><def-source>CDISC</def-source>
owl:Class
Laboratory Procedure
Interleukin 31 Measurement
The determination of the amount of interleukin 31 present in a sample.
Interleukin 31
CL384310
CDISC SDTM Laboratory Test Terminology by Code
CDISC SEND Terminology
Interleukin 31 Measurement
Interleukin 31 Measurement
Clinical Data Interchange Standards Consortium Terminology
C74829
CDISC SDTM Terminology
Molecular Genetic Technique
A procedure in which multilocus band patterns of a DNA sample are generated by digestion of the DNA with restriction enzymes followed by electrophoresis and visualization by hybridization with probes specific for repetitive sequences. In forensic medicine, the probes used are "core" sequences specific for simple tandem-repetitive sequences (MINISATELLITE REPEATS or VNTRs). The multilocus band patterns, known as DNA fingerprints, are evaluated for similarities with DNA from an individual (From MSH 2001).
DNA Footprinting
Molecular Biology Research Technique
DNA Footprinting
DNA Footprinting
owl:Class
C17890
C0282579
DNA Footprinting
Providing experimental therapies to very sick individuals even though they don't meet the critera for inclusion in a trial.
Compassionate Treatment
Compassionate Treatment
Therapeutic or Preventive Procedure
Compassionate Treatment
owl:Class
C71724
CL378265
Therapeutic Procedure
Compassionate Treatment
Tobacco Surveillance
Surveillance
Tobacco Surveillance
Tobacco Surveillance
owl:Class
CL014985
Surveillance to improve the capacity to identify and understand emerging disparities in tobacco use, particularly among at risk youth. (from The NCI Strategic Plan to Reduce Health Disparities)
Research Activity
Tobacco Surveillance
C16176
Molecular Modeling
Homology Modeling
owl:Class
CL003159
C19234
An approach to modeling a protein structure based on an initial sequence alignment to a protein with a known 3D structure. After evaluating and resolving structural irregularities in the initial model, it may be further refined using energy minimization and other procedures.
Homology Modeling
Homology Modeling
Activity
Homology Modeling
C15473
Nausea and Vomiting Therapy
antiemetic support
Nausea and Vomiting Therapy
vomiting and nausea management
owl:Class
Nausea and Vomiting Therapy
CL029170
Nausea and Vomiting Therapy
Gastrointestinal Complications Management
Therapeutic or Preventive Procedure
nausea and vomiting management
management of nausea and vomiting
Sequential Treatment
Sequential Treatment
owl:Class
CL032066
C15729
Therapeutic or Preventive Procedure
Sequential Treatment
Therapeutic Procedure
Sequential Treatment
Temporal Concept
sequential treatment
<def-source>NCI-GLOSS</def-source><def-definition>One treatment after the other.</def-definition>
Cancer Research
CL016076
Tissue Array Research Program
TARP
Tissue Array Research Program
Tissue Array Research Program
Research Activity
Tissue Array Research Program
The new Tissue Array Research Program (TARP) is a collaborative effort between the National Human Genome Research Institute and NCI to continued advances in detection, diagnosis, and development of targeted cancer therapies. Among its aims are: 1) Advance tissue microarray technology research and development, 2) Produce tissue microarrays for use by the research community, 3) Serve as an arraying facility for groups with unique tissue materials, such as clinical trial groups or consortiums of rare diseases, 4) Disseminate tissue microarray technology by providing training, workshops, establishing protocols and standards.
C16191
owl:Class
Bioterrorism Research
Bioterrorism Research
C26021
Research focused on detection of biowarfare agents and the treatment of individuals exposed to or affected by these agents.
Bioterrorism Research
owl:Class
Bioterrorism Research
Research Activity
Terrorism Research
CL053948
Special Histology Staining Method
Laboratory Procedure
Special Histology Staining Method
CL100957
Special Histology Staining Method
Special Histology Staining Method
owl:Class
Histological technique in which special stains are used to visualize specific tissue and cellular structures. These are dyes that bind to the cellular components either physically or by chemical bonds. (From Biogenex).
Staining Method
Special Histology Stains
Special Histology Staining Method
C23044
The measurement of the amount of phenylalanine in a biologic specimen.
Newborn Screening
Phenylalanine Measurement
Amino Acid Measurement
Phenylalanine Measurement
owl:Class
C81280
Phenylalanine Measurement
Laboratory Procedure
Phenylalanine Measurement
Prior Extensive Radiation
Prior Extensive Radiation
CL001443
Prior Extensive Radiation
Prior Radiation Therapy
owl:Class
Having received extensive radiation before the present time.
Clinical Attribute
Prior Extensive Radiation
C15904
Nephroureterectomy
CL355289
Urologic Surgical Procedure
Procedure_Has_Excised_Anatomy only Ureter
Therapeutic or Preventive Procedure
Nephroureterectomy
owl:Class
Nephroureterectomy
Nephroureterectomy
Procedure_Has_Excised_Anatomy only Kidney
C51646
Diagnostic Procedure
owl:Class
Percutaneous Liver Biopsy
Percutaneous Liver Biopsy
Percutaneous Liver Biopsy
CL354148
C51929
Percutaneous Needle Biopsy
Percutaneous Liver Biopsy
skin cancer early detection
Screening for Skin Cancer
early detection of skin cancer
Diagnostic Procedure
Screening for Skin Cancer
owl:Class
Cancer Screening
Screening for Skin Cancer
skin cancer screening
Screening for Skin Cancer
CL030489
C15547
Hematology Procedure
Hematology Test
Hematology Test
Hematology Test
C49286
C0200627
Clinical Pathology Procedure
Laboratory Procedure
A laboratory test that has blood as its specimen.
owl:Class
Hematology Test
A possibly-repeating collection of consecutive days that define the length of a Study Segment
C71737
Clinical Trials Design
owl:Class
CL378342
Clinical Trial Period
Research Activity
Period
Clinical Trial Period
Clinical Trial Period
Clinical Trial Period
owl:Class
Partial Mandibulectomy
Partial Excision of Mandibula
Partial Mandibulectomy
Surgery to remove part of the mandible.
Mandibulectomy
C51747
Partial Mandibulectomy
Partial Mandibulectomy
Procedure_Has_Partially_Excised_Anatomy only Mandible
CL353584
Therapeutic or Preventive Procedure
Colorectal Cancer Prevention
C15554
Prevention of Colorectal Cancer
Cancer Prevention
Prevention of Colorectal Cancer
Prevention of Colorectal Cancer
Therapeutic or Preventive Procedure
CL030496
Prevention of Colorectal Cancer
owl:Class
Principal Component Analysis
C0429865
Principal Components Analysis
Principal Component Analysis
C49291
owl:Class
Principal Component Analysis
PCA
Statistical Technique
Quantitative Concept
A vector space transform used to reduce the dimensionality in a dataset while retaining those characteristics of the dataset that contribute most to its variance.
Principal Component Analysis
Research Activity
owl:Class
Excision of Lipoma
Excision of Soft Tissue
C51769
Lipectomy
Excision of Lipoma
Excision of Lipoma
Excision of Lipoma
C0554640
Therapeutic or Preventive Procedure
Research Activity
CL003971
Tobacco Use, Combined Prevention/Cessation Research
Tobacco Use, Combined Prevention/Cessation Research
Studies to test and implement interventions among groups of individuals that are designed to both prevent the initiation of tobacco use and stop current tobacco use. (NCI/TRIP)
Tobacco Use, Combined Prevention/Cessation Research
Tobacco Use, Combined Prevention/Cessation Research
owl:Class
C15992
Combined Prevention/Cessation Research
C50822
Therapeutic Procedure
The measures applied for the restoration a person to life and/or consciousness. The act of resuscitation includes such components as artificial respiration and cardiac massage.
Resuscitation
Resuscitation
Resuscitation
CL356012
Resuscitation
owl:Class
Therapeutic or Preventive Procedure
A cardiac procedure performed under fluoroscopy to determine the area of the heart that is the source of aberrant electrical impulses that give rise to arrhythmias. Aberrant pathways can be terminated by ablation.
Cardiac Electrophysiology Study
Diagnostic Procedure
Cardiac Diagnostic Procedure
Cardiac Electrophysiology Study
C80414
Cardiac Electrophysiology Study
Cardiac Electrophysiology Study
owl:Class
Chromosome Banding
Chromosome Banding
techniques is part of technique: karyotyping
Laboratory Procedure
Cytogenetic Analysis
The treatment of chromosomes to reveal characteristic patterns of horizontal bands. The banding patterns lend each chromosome a distinctive appearance so the 22 pairs of human non-sex chromosomes and the X and Y chromosomes can be identified and distinguished without ambiguity. Banding also permits the recognition of chromosome deletions (lost segments), chromosome duplications (surplus segments) and other types of structural rearrangements of chromosomes.
C0008627
Chromosome Banding
owl:Class
<def-source>MSH2001</def-source><def-definition>Staining of bands, or chromosome segments, allowing the precise identification of individual chromosomes or parts of chromosomes. Applications include the determination of chromosome rearrangements in malformation syndromes and cancer, the chemistry of chromosome segments, chromosome changes during evolution, and, in conjunction with cell hybridization studies, chromosome mapping.</def-definition>
C16437
Chromosome Banding
<def-source>CDISC</def-source><def-definition>A measurement of the apolipoprotein A1 in the high density lipoproteins of a biological specimen.</def-definition>
Apolipoprotein A1 Measurement
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Name
Protein or Enzyme Type Measurement
Laboratory Procedure
The determination of the amount of apolipoprotein A1 present in a sample.
CL384706
CDISC
Apolipoprotein A1 Measurement
CDISC SEND Terminology
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
APOA1
Apolipoprotein A1
C74733
Apolipoprotein A1 Measurement
owl:Class
Apolipoprotein A1 Measurement
Split
Split
C54572
Activity
Instruction Imperative
CL357912
Action
Split
owl:Class
Splitting
To separate or divide into distinct parts or portions.
Split
Clinical Data Interchange Standards Consortium Terminology
<def-source>CDISC</def-source><def-definition>A measurement of the insulin in a biological specimen.</def-definition>
Insulin Measurement
INSULIN
CDISC
owl:Class
Hormone Measurement
Insulin Measurement
Insulin Measurement
Insulin Measurement
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Code
C0202098
The determination of the amount of insulin present in a sample.
Insulin
CDISC SDTM Terminology
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Name
C74788
Any surgical procedure performed subsequent to a primary or initial surgical procedure.
Additional Surgical Procedure
CL354915
Surgical Procedure
Additional Surgical Procedure
Additional Surgical Procedure
Therapeutic or Preventive Procedure
Additional Surgery
owl:Class
Additional Surgical Procedure
C50831
owl:Class
Technology Development
Research Activity
Technology Development
C0599834
Technology Development
Research Activity
C15664
Technology Development
Research Activity
Animal Alternative
C15182
C0003059
Animal Testing Alternative
Animal Testing Alternative
owl:Class
Animal Testing Alternative
Animal Testing Alternative
Any method or technique that eliminates the use of animals in experiments, research, and testing.
Research Activity
Blood Transfusion
Health Care Activity
Blood Treatment
Infusion Procedure
Transfusion of Blood Products
transfusion
owl:Class
Blood Transfusion
The injection of whole blood or a blood component directly into the bloodstream.
Blood Component Transfusion
Blood Transfusion
<def-source>NCI-GLOSS</def-source><def-definition>The administration of blood or blood products into a blood vessel.</def-definition>
Therapeutic or Preventive Procedure
blood transfusion
Blood Transfusion
Transfusion
C15192
C0085430
Newborn Screening
Bone Marrow Smear
CL386737
CDISC SEND Terminology
Bone Marrow Smear
CDISC SEND Biospecimens Terminology
Blood Smear
A laboratory procedure in which cells from bone marrow aspirate are spread thinly on a glass slide for microscopic examination. The study of bone marrow smears is routinely used for the investigation, diagnosis, and staging of hematopoietic disorders.
Laboratory Procedure
Bone Marrow Smear
owl:Class
Bone Marrow Smear
C77609
Open Lung Biopsy
C51923
Open Biopsy of Lung
CL354755
Lung Biopsy
Removal of tissue from the lung, for microscopic examination, obtained during an open surgical procedure.
Open Lung Biopsy
owl:Class
Diagnostic Procedure
Open Lung Biopsy
Open Lung Biopsy
Serum HDL Cholesterol Measurement
Lipid Measurement
Serum HDL Cholesterol Measurement
Serum HDL Cholesterol Measurement
C0428472
<def-source>CDISC</def-source><def-definition>A measurement of the high density lipoprotein cholesterol in a biological specimen.</def-definition>
C61041
CDISC SEND Terminology
owl:Class
CDISC SDTM Terminology
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Code
A quantitative measurement of the amount of HDL cholesterol present in a sample of serum.
Serum Chemistry Measurement
CDISC
Serum HDL Cholesterol Measurement
HDL
HDL Cholesterol
Laboratory Procedure
Serum HDL Cholesterol
CDISC SDTM Laboratory Test Terminology by Name
Hemilaryngectomy
owl:Class
Procedure_Has_Partially_Excised_Anatomy only Larynx
Hemilaryngectomy
Laryngectomy
Therapeutic or Preventive Procedure
Surgery to remove one half of the larynx.
C51906
Hemilaryngectomy
CL354594
Hemilaryngectomy
Nutrition, Vitamin D
Nutrition, Vitamins
Nutrition, Vitamin D
Research Activity
owl:Class
C16225
Nutrition, Vitamin D
CL102238
Nutrition, Vitamin D
Laboratory Procedure
Routine Histology Staining Method
Routine Histology Staining Method
Routine Histology Staining Method
Routine Histology Staining Method
owl:Class
CL100956
C23043
Routine Histology Stains
Staining Method
Routine Histology Staining Method
"Routine" histology staining generally refers to staining performed using hematoxylin and eosin. Hematoxylin stains the nuclei in cells and other cationic elements purple. Eosin is an anionic dye and binds to cytoplasmic proteins below pH6 giving a pink color. (From Biogenex)
Surgical replacement of all parts of a damaged knee joint with an artificial joint.
Arthroplasty of the Knee
Total Arthroplasty of the Knee
Therapeutic or Preventive Procedure
CL354833
Total Arthroplasty of the Knee
Total Arthroplasty of the Knee
Procedure_Has_Completely_Excised_Anatomy only 'Knee Joint'
Total Arthroplasty of the Knee
C51565
owl:Class
Nutrition, Dietary Components
Nutrition, Fats
Nutrition, Fats
Lipid Nutrition, Fats
Nutrition, Fats
Dietary Fat
Nutrition, Fats
owl:Class
Role of dietary fats in cancer causation or prevention and in general health.
CL357341
Research Activity
C15224
Avoidance
CL357230
Avoidance
A conscious or unconscious refusal to encounter situations, activities, or objects; the act or practice of keeping away from or withdrawing from something.
Avoidance
Behavior
C54264
owl:Class
Avoidance
Individual Behavior
CL001238
Research Activity
C15897
Causation Research
Cancer Causation Research
Cancer Causation Research
Cancer Causation Research
Cancer Research
Cancer causation research studies the events involved in the initiation and promotion of cancer. It encompasses chemical and physical carcinogenesis, biological carcinogenesis, epidemiology, chemoprevention, and nutrition research. Studies focus on external agents such as chemicals, radiation, fibers and other particles, viruses, parasitic infections, and host factors such as hormone levels, nutritional and immunologic status, and the genetic endowment of the individual, all of which contribute to the initiation and promotion of cancer.
Cancer Causation Research
owl:Class
Boldenone Measurement
Boldenone Measurement
Boldenone Measurement
Laboratory Procedure
C0524033
C75380
Boldenone Measurement
Steroid Measurement
owl:Class
The determination of the amount of boldenone present in a sample.
C0029189
Surgical removal of one or both testicles.
Orchiectomy
Male Castration
Therapeutic or Preventive Procedure
Orchiectomy
Procedure_Has_Excised_Anatomy only Testis
orchiectomy
owl:Class
<def-source>NCI-GLOSS</def-source><def-definition>(or-kee-EK-toe-mee) Surgery to remove one or both testicles.</def-definition>
Orchiectomy
Male Gonadectomy
C15288
Orchiectomy
Surgical Castration
Castration
Radiation Ionizing, Diagnostic Imaging
Diagnostic Imaging
Radiation Ionizing, Diagnostic Imaging
Radiation Ionizing, Diagnostic Imaging
CL000809
A technique for medical imaging that uses ionizing radiation like X-rays and gamma rays. Both x-rays and gamma rays are high energy, short wavelength electromagnetic radiation that are capable of penetrating and passing through most tissues. The technique is highly useful to determine the presence or absence of a specific medical condition.
C18980
Radiation Ionizing, Diagnostic Imaging
owl:Class
Diagnostic Procedure
CDISC SDTM Terminology
LYMMCE
<def-source>CDISC</def-source><def-definition>A measurement of the malignant lymphocytes in a biological specimen.</def-definition>
Lymphoma Cell Count
Laboratory Procedure
Lymphoma Cell Count
CDISC SDTM Laboratory Test Terminology by Code
Lymphoma Cell Count
Clinical Data Interchange Standards Consortium Terminology
The determination of the number of lymphoma cells present in a sample.
CDISC SDTM Laboratory Test Terminology by Name
owl:Class
Atypical Lymphocyte Count
CDISC
CL384273
CDISC SEND Terminology
Lymphoma Cells
C74613
Lymphoma Cell Count
C0560738
Diagnostic Procedure
owl:Class
C38100
Ventilation-Perfusion Scan
Ventilation Perfusion Scanning
Radionuclide Imaging
Ventilation Perfusion Scanning
Ventilation Perfusion Scanning
Ventilation Perfusion Scanning
A nuclear imaging test that uses radiopharmaceuticals to produce an image of the blood flow to the lungs and measures the ability of the lungs to take in air as well as air distribution in the lungs.
Laboratory Procedure
Chemical Fractionation
Biomolecule Separations Technology
Chemical Fractionation
Fractionation, Chemical
Chemical Fractionation
C18800
Chemical Fractionation
C0016640
owl:Class
Methods of fractionation, isolation, and purification based on the physico-chemical properties of the substance, e.g. crystallization, distillation, solubility (miscibility).
Dismiss
Dismissed
Bar from attention or consideration; cease to consider.
Activity
CL378312
Dismiss
Dismiss
owl:Class
Dismiss
C71730
Action
CL013980
A treatment approved by FDA for treatment following surgery for melanoma patients who are at high risk of disease recurrence. (Bypass Budget)
High Dose Chemotherapy
Therapeutic or Preventive Procedure
owl:Class
High Dose Interferon Alpha 2a
High Dose Interferon Alpha 2a
High Dose Interferon Alpha 2a
Interferon Therapy
C16125
High Dose Interferon Alpha 2a
C26022
Genetic Testing Research, Human
Biomedical Research
CL053950
Genetic Testing Research, Human
owl:Class
Genetic Testing Research, Human
Genetic Testing Research, Human
Research Activity
Action
The act of destroying; demolition or annihilation.
Activity
Destruction
C62100
Destruction
owl:Class
Destruction
CL385671
Destruction
Starch Crystal Measurement
Chemistry Test
owl:Class
Starch Crystal Measurement
The determination of the amount of starch crystals present in a sample.
Starch Crystal Measurement
C81951
Starch Crystal Measurement
Removal of cancerous cells from bone marrow before it is transplanted.
Tumor Purging
Health Care Activity
CL353156
Bone Marrow Purging
Bone Marrow Purging
owl:Class
C51992
Bone Marrow Purging
Bone Marrow Purging
Dose Modification
CDISC SDTM Trial Summary Parameter Terminology by Name
CDISC SDTM Terminology
<def-source>CDISC</def-source><def-definition>The addition of a therapeutic product to the existing regimen in a clinical trial, where both entities remain as discrete products.</def-definition>
CDISC
Test Product Added to Existing Treatment
Test Product Added to Existing Treatment
owl:Class
ADDON
CDISC SDTM Trial Summary Parameter Terminology by Code
CL354258
Research Activity
An indication that an investigational drug or substance has been added to the existing treatment regimen.
Clinical Data Interchange Standards Consortium Terminology
Added on to Existing Treatments
C49703
Test Product Added to Existing Treatment
Test Product Added to Existing Treatment
C79751
Procedure
owl:Class
Procedure
Procedure
Any stepwise set of actions.
Procedure
Activity
Action
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
Lymphoma Cell to Lymphocyte Ratio Measurement
owl:Class
LYMMCELY
CDISC
CDISC SEND Terminology
Lymphoma Cell to Lymphocyte Ratio Measurement
C74910
Laboratory Procedure
Blood Cell Count Ratio Measurement
Lymphoma Cell to Lymphocyte Ratio Measurement
CDISC SDTM Laboratory Test Terminology by Name
Lymphoma Cells/Lymphocytes
CL384409
Lymphoma Cell to Lymphocyte Ratio Measurement
<def-source>CDISC</def-source><def-definition>A relative measurement (ratio or percentage) of the malignant lymphocytes to all lymphocytes in a biological specimen.</def-definition>
The determination of the ratio of lymphoma cells compared to lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
Clinical Data Interchange Standards Consortium Terminology
Clinical Data Interchange Standards Consortium Terminology
Magnesium to Creatinine Ratio Measurement
Urine Protein Measurement
MGCREAT
C79456
Magnesium to Creatinine Ratio Measurement
owl:Class
Magnesium/Creatinine
<def-definition>A relative measurement (ratio or percentage) of the magnesium to creatinine in a biological specimen.</def-definition><def-source>CDISC</def-source>
Magnesium to Creatinine Ratio Measurement
The determination of the ratio of magnesium compared to creatinine present in a sample. The measurement may be expressed as a ratio or percentage.
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
CDISC SDTM Terminology
Magnesium to Creatinine Ratio Measurement
CDISC SDTM Laboratory Test Terminology by Code
owl:Class
Representational Oligonucleotide Microarray Analysis
Representational Oligonucleotide Microarray Analysis
ROMA
Microarray Analysis
Representational Oligonucleotide Microarray Analysis
Laboratory Procedure
C0445583
A genomic microarray-based method able to identify regions in the cancer genome that have undergone copy number fluctuation. This method is reported to be highly sensitive and quantitative, able to detect loss of a single allele. See: Genome Res. 2003 Oct;13(10):2291-305. Epub 2003 Sep 15.
C40211
Representational Oligonucleotide Microarray Analysis
A therapeutic procedure involving the insertion of an inflatable balloon catheter filled with radioactive material into a resection cavity in order to deliver radiation to any remaining cancer cells in and around the tumor bed.
Radiation Brachytherapy
CL369400
Therapeutic or Preventive Procedure
Balloon Brachytherapy
Balloon Brachytherapy
C64385
Balloon Brachytherapy
Balloon Brachytherapy
owl:Class
Chromogenic in situ Hybridization
Laboratory Procedure
A laboratory procedure that combines the sequence-specific detection aspects of FISH with the simple detection methods of immunohistochemistry. Briefly, sequence-specific probes are hybridized to cells fixed on slides and the sequestered probe is visualized by a peroxidase reaction. It has the advantage of being a less costly assay that does not require fluorescence microscopy with results that are stable over time.
Chromogenic in situ Hybridization
Molecular Biology Research Technique
Chromogenic in situ Hybridization
CISH
owl:Class
Chromogenic in situ Hybridization
in situ Hybridization
C40960
C1516514
C16016
owl:Class
Research Activity
CL004428
Nutrition, Vitamins
Nutrition, Vitamins
Nutrition, Vitamins
Nutrition, Dietary Components
Nutrition, Vitamins
Clinical Data Interchange Standards Consortium Terminology
<def-definition>A measurement of the phencyclidine present in a biological specimen.</def-definition><def-source>CDISC</def-source>
Phenylcyclohexylpiperidine
C0202445
Phencyclidine Measurement
CDISC SDTM Laboratory Test Terminology by Code
Hallucinogen Measurement
PCP
CDISC SDTM Terminology
CDISC SEND Terminology
Laboratory Procedure
owl:Class
Phencyclidine Measurement
The determination of the amount of phencyclidine present in a sample.
Phencyclidine Measurement
Phencyclidine
C74694
Phencyclidine Measurement
PCP Measurement
CDISC SDTM Laboratory Test Terminology by Name
Gamma Distribution
Exponential Distribution
Gamma-Distribution
C53223
Gamma Distribution
A two-parameter family of continuous probability distributions, with a scale parameter theta and a shape parameter k.
Quantitative Concept
owl:Class
Gamma Distribution
Gamma Distribution
CL355718
C15995
The basic relationships between biological and behavioral factors and/or their potential relationship to prevention and/or cessation interventions.
Behavioral Research
owl:Class
Research Activity
Behavioral and Biological Associations
CL003983
Behavioral/ Biological Associations
Behavioral and Biological Associations
Behavioral and Biological Associations
Behavioral and Biological Associations
Treatment Regimen
Treatment Regimen
Treatment Regimen
owl:Class
CL031856
Treatment Schedule
regimen
Functional Concept
Regimen
Treatment Regimen
<def-source>NCI-GLOSS</def-source><def-definition>A treatment plan that specifies the dosage, the schedule, and the duration of treatment.</def-definition>
Treatment Protocol
C15697
Therapeutic Procedure
owl:Class
Repository Operation, Tissue
Culturing, in vitro Vertebrate Repository Operations, Tissue
CL003783
Repository Operation, Tissue
Repository Operation
Repository Operation, Tissue
Laboratory Procedure
Repository Operation, Tissue
C15978
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Name
CDISC
C61032
Lipid Measurement
Clinical Data Interchange Standards Consortium Terminology
Laboratory Procedure
Serum Total Cholesterol Measurement
A quantitative measurement of the total amount of cholesterol present in a sample of serum.
Total Cholesterol
Serum Total Cholesterol Measurement
Serum Total Cholesterol Measurement
Cholesterol
Serum Total Cholesterol Measurement
CL385608
CHOL
<def-source>CDISC</def-source><def-definition>A measurement of the cholesterol in a biological specimen.</def-definition>
CDISC SDTM Terminology
Serum Chemistry Measurement
CDISC SDTM Laboratory Test Terminology by Code
owl:Class
Therapeutic or Preventive Procedure
Shark Cartilage Therapy
Shark Cartilage Therapy
Shark Cartilage Therapy
CAM Pharmacological or Biological Treatment
C67028
CL371476
owl:Class
Shark Cartilage Therapy
Estradiol Measurement
C74782
Laboratory Procedure
The determination of the amount of estradiol present in a sample.
<def-source>CDISC</def-source><def-definition>A measurement of the estradiol in a biological specimen.</def-definition>
Estradiol Measurement
Estradiol
ESTRDIOL
C0337434
Estradiol Measurement
owl:Class
CDISC SDTM Terminology
CDISC
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Laboratory Test Terminology by Name
Hormone Measurement
Oestradiol
Clinical Data Interchange Standards Consortium Terminology
Estradiol Measurement
CDISC SEND Terminology
C75385
Peptide Hormone Measurement
owl:Class
Drug Class Measurement
The determination of the amount of any peptide hormone present in a sample.
Peptide Hormone Measurement
Laboratory Procedure
Peptide Hormone Measurement
Peptide Hormone Measurement
CL384647
owl:Class
Stratified Sampling
Sampling Method
C0681883
Stratified Sampling
Quantitative Concept
C71516
Stratified Sampling
Stratified Sampling
CL355450
Repeated Surgical Procedure
Repeated Surgical Procedure
Repeated Surgical Procedure
Therapeutic or Preventive Procedure
Surgical Procedure
C50830
Repeated Surgical Procedure
owl:Class
Genetic Population Study
Genetic Population Study
Genetic Population Study
C16160
CL014450
owl:Class
Population Study
Research Activity
Genetic Population Study
Laboratory Procedure
Sister Chromatid Exchange Assay
C19561
CL004813
owl:Class
Sister Chromatid Exchange Assay
Sister Chromatid Exchange Assay
Sister Chromatid Exchange Assay
DNA Analysis
SCE Assay
The sister chromatid exchange (SCE) assay detects the ability of a chemical mutagen to enhance the exchange of DNA between two sister chromatids of a duplicating chromosome. The test may be performed in vitro, using, for example, rodent or human cells, or in vivo using mammals, for example, rodents such as mice, rats and hamsters. Sister chromatid exchanges are reciprocal interchanges of the two chromatid arms within a single chromosome. These exchanges are visualized during the metaphase portion of the cell cycle and presumably require enzymatic incision, translocation and ligation of at least two DNA helices.
Synovial Biopsy
Biopsy
Synovial Biopsy
Synovial Biopsy
owl:Class
C51731
Diagnostic Procedure
Removal of synovial tissue for microscopic examination.
CL355531
Procedure_Has_Partially_Excised_Anatomy only 'Synovial Membrane'
Synovial Biopsy
CDISC SDTM Laboratory Test Terminology by Name
<def-definition>A measurement of the lactate dehydrogenase isoenzyme 5 in a biological specimen.</def-definition><def-source>CDISC</def-source>
Lactate Dehydrogenase Isoenzyme 5 Measurement
LDH5
The determination of the lactate dehydrogenase isoenzyme 5 present in a sample.
Protein or Enzyme Type Measurement
Lactate Dehydrogenase Isoenzyme 5 Measurement
owl:Class
Lactate Dehydrogenase Isoenzyme 5 Measurement
CDISC SDTM Terminology
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Code
Lactate Dehydrogenase Isoenzyme 5 Measurement
LDH Isoenzyme 5
Laboratory Procedure
C74891
CDISC SEND Terminology
CL384325
Endocrine Surgical Procedure
Endocrine Therapy
Therapeutic or Preventive Procedure
Endocrine Surgical Procedure
Endocrine Surgical Procedure
Procedure_Has_Target_Anatomy only 'Endocrine System'
Endocrine Surgical Procedure
C52011
CL354543
Therapeutic Surgical Procedure
owl:Class
Surgical Procedure by Site or System
C71498
Proportional Stratified Sampling
Proportional Stratified Sampling
Stratified Random Sampling
Proportional Stratified Sampling
CL378138
owl:Class
Proportional Stratified Sampling
Quantitative Concept
Peak Expiratory Flow
C41372
CL331977
Quantitative Concept
Peak Expiratory Flow (PEF) - one of the lung function testing parameters measuring the rate at which a patient can exhale for vital lung capacity evaluation. PEF records the maximum flow that can be sustained for 10 milliseconds on forced expiration starting from full inflation of the lungs. It is a useful tool in defining characteristics and monitoring such conditions as obstructive lung disease, asthma, and bronchitis.
Peak Expiratory Flow
Pulmonary Function Test
Peak Expiratory Flow
owl:Class
Peak Expiratory Flow
owl:Class
Research Activity
Role of plant-derived nutrients in cancer causation or prevention and in general health.
Nutrition, Dietary Components
Nutrition, Plant Components
Nutrition, Plant Components
C15919
CL002953
Nutrition, Plant Components
Nutrition, Plant Components
Vitamin B3 Measurement
owl:Class
Vitamin B3 Measurement
Vitamin B3
Clinical Data Interchange Standards Consortium Terminology
<def-definition>A measurement of the niacin in a biological specimen.</def-definition><def-source>CDISC</def-source>
Laboratory Procedure
CL384440
Vitamin B3 Measurement
Vitamin Measurement
C74899
CDISC SDTM Laboratory Test Terminology by Code
VITB3
Niacin
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Name
The determination of the amount of Vitamin B3 present in a sample.
Vitamin B3 Measurement
CDISC SEND Terminology
Immunotherapy
Immunoglobulin Therapy
owl:Class
C62710
Immunoglobulin Therapy
Immunoglobulin Therapy
C0021022
Immunoglobulin Therapy
Therapeutic or Preventive Procedure
Genetic Testing
Disease Screening
genetic testing
Laboratory Procedure
Molecular Analysis
Genetic Testing
C15709
Genetic Testing
Genetic Testing
Genetic Examination
<def-source>NCI-GLOSS</def-source><def-definition>Analyzing DNA to look for a genetic alteration that may indicate an increased risk for developing a specific disease or disorder.</def-definition>
owl:Class
C0679560
Newborn Screening
Diagnostic Procedure
Procedure_Has_Target_Anatomy only 'Small Intestine'
ileostomy
C15257
Procedure_Has_Target_Anatomy only Ileum
Surgical creation of an external opening into the ileum for fecal diversion or drainage. Loop or tube procedures are most often employed. (MeSH)
owl:Class
Ileostomy
C0020883
Ileostomy
Ileostomy
Therapeutic or Preventive Procedure
Enterostomy
<def-source>NCI-GLOSS</def-source><def-definition>(il-ee-AHS-toe-mee) An opening into the ileum, part of the small intestine, from the outside of the body. An ileostomy provides a new path for waste material to leave the body after part of the intestine has been removed.</def-definition>
Ileostomy
Store
CL360789
Action
Storage
C60824
Storage
Instruction Imperative
owl:Class
The act of safekeeping goods in a depository.
Storage
Storage
Activity
<def-source>NCI-GLOSS</def-source><def-definition>(kyoo-reh-TAHZH) Removal of tissue with a curette, a spoon-shaped instrument with a sharp edge.</def-definition>
Curettage Procedure
Surgical Procedure by Method
curettage
<def-source>MSH2001</def-source><def-definition>A scraping, usually of the interior of a cavity or tract, for removal of new growth or other abnormal tissue, or to obtain material for tissue diagnosis. It is performed with a curet (curette), a spoon-shaped instrument designed for that purpose. (From Stedman, 25th ed &amp; Dorland, 27th ed)</def-definition>
C15216
Curettage Procedure
Curettage Procedure
owl:Class
Curettage Procedure
C0010468
Curettage
Diagnostic Procedure
Therapeutic or Preventive Procedure
Squamous Transitional Epithelial Cell Count
CDISC
Epithelial Cells
owl:Class
CDISC SDTM Terminology
Epithelial Cell Count
Clinical Data Interchange Standards Consortium Terminology
Urine Sediment Analysis Measurement
The determination of the number of squamous transitional epithelial cells present in a urine sample.
CDISC SEND Terminology
Squamous Transitional Epithelial Cell Count
CDISC SDTM Laboratory Test Terminology by Code
Squamous Transitional Epithelial Cell Count
C74774
CL384352
Squamous Transitional Epithelial Cells
Squamous Transitional Epithelial Cell Count
CDISC SDTM Laboratory Test Terminology by Name
<def-source>CDISC</def-source><def-definition>A measurement of the squamous transitional epithelial cells present in a urine specimen.</def-definition>
Laboratory Procedure
EPISQTCE
The determination of the amount of active glucagon-like peptide-1 present in a sample.
owl:Class
Active Glucagon-like Peptide-1 Measurement
Protein or Enzyme Type Measurement
Active Glucagon-like Peptide-1 Measurement
Active Glucagon-like Peptide-1 Measurement
Active Glucagon-like Peptide-1 Measurement
Laboratory Procedure
C80164
Cardiac Diagnostic Procedure
CL008680
Diagnostic Procedure
owl:Class
C16094
Diagnostic Procedure
Cardiac Diagnostic Procedure
Cardiac Diagnostic Procedure
Cardiac Function Study
The study and analysis of the normal or abnormal functioning of the heart using methods such as echocardiography, exercise stress cardiography, 24-hour Holter EKG and magnetic resonance imaging.
Cardiac Diagnostic Procedure
CL040094
Surgical Procedure
C50823
Prolonged Surgery
Prolonged Surgery
Prolonged Surgery
Therapeutic or Preventive Procedure
Prolonged Surgery
owl:Class
Override
Override
Override
C67529
CL371950
To take precedence over and countermand, thereby allowing an activity to continue despite a warning or error.
Over-ride
Override
owl:Class
Action
Activity
Neutrophil Count
CL354739
Neutrophil Count
owl:Class
Neutrophil Count
Laboratory Procedure
Neutrophil Count
C51950
A test to determine the number of neutrophils in a sample of blood.
Leukocyte Count
CL354754
Open Biopsy of Kidney
C51732
owl:Class
Open Renal Biopsy
Removal of tissue from the kidney, for microscopic examination, performed during an open surgical procedure.
Open Biopsy of Kidney
Kidney Biopsy
Diagnostic Procedure
Open Biopsy of Kidney
Open Biopsy of Kidney
Isotonics
Daily or Recreational Activity
owl:Class
Isotonic Exercise
Exercise
CL330036
This exercise can build strength and endurance.
Isotonic Exercise
C21058
An exercise that involves the movement of a constant weight or load through a specified range of motion.
Isotonic Exercise
Isotonic Exercise
owl:Class
Corner Minus
CL371501
Activity
Corner M
C67054
Corner Minus
Corner Minus
The average cell intensity for the antisense probe cells used in the grid alignment process.
Corner -
Corner Minus
Statistical Technique
Excision
CL353551
Myectomy
Myectomy
Myectomy
C51591
Myectomy
owl:Class
Therapeutic or Preventive Procedure
Immunotoxin Therapy
Immunotoxin Therapy
Immunotherapy
Immunotoxin Therapy
Therapeutic or Preventive Procedure
C15739
Immunotoxin Therapy
owl:Class
CL032241
CL029145
Evaluation of Cancer Risk Factors
Disease Screening
Evaluation of Cancer Risk Factors
C15455
Evaluation of Risk Factors
owl:Class
Health Care Activity
Evaluation of Cancer Risk Factors
cancer risk factors evaluation
Evaluation of Cancer Risk Factors
Multidimensional NMR Techniques
Multidimensional NMR Techniques
Multidimensional NMR Techniques
Research Activity
CL004896
C19577
Magnetic Resonance Imaging
owl:Class
Multidimensional NMR Techniques
Various NMR methods that can be used to determine 3D structures of macromolecules.
Activity
Move
Moved
Relocation
Action
The act of changing your residence or place of business.
C77951
owl:Class
Relocation
Relocation
Relocated
Relocation
CL387432
CL000083
Autoradiography
Autoradiographic analysis performed in accordance with specified guidelines that will result in a defined correspondence between the intensity of the autoradiographic image and the amount of radioactivity present in the sample. This permits assignment of a value to the amount of radioactive material in the object under study.
Quantitative Autoradiography
C18639
Laboratory Procedure
Diagnostic Procedure
Quantitative Autoradiography
owl:Class
Autoradiography, Quantitative
Quantitative Autoradiography
Quantitative Autoradiography
C0199470
C70909
Mechanical Ventilation
owl:Class
Mechanical Ventilation
Mechanical Ventilation
A method to mechanically assist or replace spontaneous breathing in patients by use of a powered device that forces oxygenated air into the lungs.
Mechanical Ventilation
Therapeutic Procedure
Therapeutic or Preventive Procedure
CL355825
C53216
owl:Class
A normal distribution which models only a single variable of interest. Like the normal distribution, its shape and position are determined by the mean of the set of observations (location parameter) and its standard deviation (scale parameter).
Univariate Normal Distribution
Univariate Normal Distribution
Normal Distribution
Univariate Normal Distribution
Univariate Normal Distribution
Quantitative Concept
Average Difference Probe Summary Method
Probe Summary Method
Activity
CL369063
Bioconductor caAffy Average Difference Probe Summary Method
Summarizes probe sets by computing the average difference between all PM and MM probes in a probe set. Defined in the documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html
Bioconductor caAffy Average Difference Probe Summary Method
C64222
Average Difference
owl:Class
Bioconductor caAffy Average Difference Probe Summary Method
Bioconductor caAffy Average Difference Probe Summary Method
Neuraxial Opioid Analgesia
Neuraxial Opioid Analgesia
Analgesic delivery into the spinal axis.
Neuraxial Opioid Analgesia
C21073
Neuraxial Opioid Analgesia
CL102850
Regional Anesthesia Procedure
owl:Class
Therapeutic or Preventive Procedure
Cardiac Catheterization
Cardiac Catheterization
Cardiovascular Surgical Procedure
Cardiac Catheterization
C0018795
C38044
A procedure in which a thin plastic tube (catheter) is inserted into an artery or vein in the arm or leg and then advanced into the chambers of the heart or into the coronary arteries. Catheterization can measure blood pressure within the heart and how much oxygen is in the blood. It's also used to get information about the pumping ability of the heart muscle. Catheters are also used to inject dye into the coronary arteries. Catheters with a balloon on the tip are used in the procedure called percutaneous transluminal coronary angioplasty.
Procedure_Has_Target_Anatomy some Heart
Health Care Activity
Cardiac Catheterization
owl:Class
To make something conform to a standard; to remove useless or extraneous entries from a data set.
Normalize
C62007
owl:Class
Action
CL086744
Normalize
Normalized
Normalize
Activity
Normalization
Normalize
owl:Class
The determination of the amount of interferon gamma present in a sample.
Interferon Gamma Measurement
C81996
Interferon Gamma Measurement
Interferon Measurement
Interferon Gamma Measurement
Interferon Gamma Measurement
Nanotechnology Techniques
Optical Tweezers
Laboratory Procedure
owl:Class
Optical Tweezers
C62320
Optical Tweezers
Optical Tweezers
A technique that utilizes light waves to exert minute forces as well as transmit energy to isolate and manipulate nanoparticles.
CL364955
Food
Dietary
diet
owl:Class
Diet
Diet
C15222
The customary allowance of food and drink taken by a person or an animal from day to day, particularly one especially planned to meet specific requirements of the individual, including or excluding certain items of food; a prescribed course of eating and drinking in which the amount and kind of food, as well as the times at which it is to be taken, are regulated for therapeutic purposes or selected with reference to a particular state of health.
<def-source>NCI-GLOSS</def-source><def-definition>The things a person eats and drinks.</def-definition>
Diet
C0012155
Diet
Diet and Nutrition
Clinical Data Interchange Standards Consortium Terminology
The determination of the amount of Vitamin B5 present in a sample.
C74900
Vitamin Measurement
VITB5
Vitamin B5 Measurement
owl:Class
Vitamin B5
CDISC SDTM Laboratory Test Terminology by Code
Laboratory Procedure
Vitamin B5 Measurement
Vitamin B5 Measurement
CDISC SDTM Laboratory Test Terminology by Name
Vitamin B5 Measurement
CDISC SDTM Terminology
CDISC SEND Terminology
CL384441
Pantothenic Acid
<def-definition>A measurement of the Vitamin B5 in a biological specimen.</def-definition><def-source>CDISC</def-source>
C0016352
An analytical method that utilizes ultraviolet light to excite the sample and detects the fluorescence emitted during the return of the sample to its ground state.
Fluorimetry
C62322
owl:Class
Fluorimetry
Fluorimetry
Fluorimetry
Physical Chemical Technique
Laboratory Procedure
CL017737
C20117
Diagnostic Procedure
MRI method that measure the diffusion of water in the tissue, rather than the content of water as measured in conventional MRI.
Diffusion MRI
owl:Class
Diffusion MRI
Magnetic Resonance Imaging
Diffusion MRI
Diffusion MRI
Referral
owl:Class
Newborn Screening
Sending a patient from one practitioner to another for health care services.
C0034927
Activity
Referral
Referral
Action
C52582
Referral
Action
The creation of a two-dimensional graphic representation of an area or structure, showing the relative position of features or characteristics.
Activity
Mapping
CL384199
Mapping
Mapping
Mapping
owl:Class
C73942
Immunoglobulin G Measurement
C81971
Immunoglobulin G Measurement
Immunoglobulin G Measurement
Immunoglobulin G Measurement
owl:Class
The determination of the amount of immunoglobulin G present in a sample.
Immunoglobulin Measurement
Rectal Biopsy
Rectal Biopsy
Rectal Biopsy
Removal of rectal tissue, for microscopic examination.
C51693
Biopsy of Rectum
owl:Class
Rectal Biopsy
CL355992
Endoscopic Biopsy
Procedure_Has_Partially_Excised_Anatomy only Rectum
Diagnostic Procedure
Developmental Therapy
Developmental Therapeutics
owl:Class
Developmental Therapeutics Program
Developmental Therapeutics Program
Cancer Research
Research Activity
Developmental Therapeutics Program
DTP
Developmental Therapeutics Program
As the drug discovery and development arm of the National Cancer Institute, the Developmental Therapeutics Program (DTP) plans, conducts, and facilitates development of therapeutic agents for cancer and AIDS. They are a resource for research materials, including Web-accessible data and tools, vialed and plated compounds, tumor cells, animals, and Investigational New Drug (IND)-directed studies. (DTP web site)
C1522647
C16009
Contrast-enhanced Magnetic Resonance Imaging
CL342950
Contrast-enhanced Magnetic Resonance Imaging
C46087
Diagnostic Procedure
Contrast-enhanced Magnetic Resonance Imaging
A technique that uses radiofrequency waves and a magnet to image the body. The images are enhanced by the addition of contrast agents which selectively intensify anatomical regions to intensify the clarity of the image for diagnostic purposes. 2005
Magnetic Resonance Imaging
owl:Class
Contrast-enhanced MRI
Contrast-enhanced Magnetic Resonance Imaging
Folic Acid Measurement
VITB9
CDISC SDTM Laboratory Test Terminology by Name
Folic Acid Measurement
CDISC SDTM Laboratory Test Terminology by Code
Folic Acid Measurement
Folic Acid Measurement
C74676
Vitamin B9
Folic Acid
<def-source>CDISC</def-source><def-definition>A measurement of the folic acid in a biological specimen.</def-definition>
The determination of the amount of folic acid present in a sample.
CDISC SDTM Terminology
CDISC
Laboratory Procedure
CDISC SEND Terminology
Clinical Data Interchange Standards Consortium Terminology
owl:Class
Vitamin Measurement
C0523631
Yoga
Therapeutic or Preventive Procedure
Yoga Therapy
CL384861
CAM Exercise Therapy
C64897
Yoga Therapy
Yoga Therapy
owl:Class
Yoga Therapy
Transplantation
Surgery, Transplantation
Transplantation
C15342
Transplantation
Transplantation Surgery
Transference of a tissue or organ within an individual, between individuals of the same species, or between individuals of different species.
Grafting Procedure
Transplantation
Transplant Procedure
<def-source>NCI-GLOSS</def-source><def-definition>The replacement of tissue with tissue from the person's own body or from another person.</def-definition>
owl:Class
C0040732
Therapeutic Procedure
Therapeutic or Preventive Procedure
transplantation
The determination of the amount of extracellular newly identified RAGE (receptor for advanced glycation end products) present in a sample.
Extracell Newly Ident RAGE Bind Protein Measurement
Extracell Newly Ident RAGE Bind Protein Measurement
C82011
Protein or Enzyme Type Measurement
Extracell Newly Ident RAGE Bind Protein Measurement
Extracell Newly Ident RAGE Bind Protein Measurement
owl:Class
Ablative Endocrine Surgery
Adrenal Gland Excision
C15177
Abdominal Surgical Procedure
Procedure_Has_Excised_Anatomy only 'Adrenal Gland'
Therapeutic or Preventive Procedure
Adrenalectomy
owl:Class
Excision of Adrenal Gland
C0001632
Adrenalectomy
Adrenalectomy
Adrenalectomy
Surgical removal of part or all of the adrenal gland.
owl:Class
Activity
Cessation
Cessation
Cessation
Action
A stopping.
Cessation
CL364485
C61497
Protein or Enzyme Type Measurement
Glutamic Acid Decarboxylase 1 Measurement
The determination of the amount of glutamic acid decarboxylase 1 present in a sample.
Glutamic Acid Decarboxylase 1 Measurement
owl:Class
Glutamic Acid Decarboxylase 1 Measurement
C82015
Glutamic Acid Decarboxylase 1 Measurement
Biological Response Modifiers Program
Biological Response Modifiers Program
Governmental or Regulatory Activity
C1511147
Cancer Research
Biological Response Modifiers Program
owl:Class
A program set up to establish cooperative agreements for Clinical Trials of Cancer Therapy with Biological Response Modifiers (CATBRMs) and to develop novel approaches for such therapy. Funding is provided to foster innovative clinical trials of BRMs by peer-reviewed groups of highly experienced clinical and preclinical investigators who have the unique technical capabilities to study new agents in early clinical trials and to address hypothesis-driven issues of mechanisms of action.
BRMP
Biological Response Modifiers Program
C15772
Computational Technique
Computational Technique
C19233
Computational Technique
Technique
Activity
Computational
The utilization or development of computer programs to solve, analyze, understand or manage any simple or complex task.
owl:Class
Computational Technique
C1516769
Biopsy of Pancreas
Biopsy of Pancreas
Pancreatic Biopsy
Diagnostic Procedure
Biopsy of Pancreas
Biopsy of Pancreas
Procedure_Has_Partially_Excised_Anatomy only Pancreas
CL354998
owl:Class
C51671
Biopsy
Removal of tissue from the pancreas for microscopic examination.
C16102
Investigator-Initiated Research
Investigator-Initiated Research
owl:Class
Research Activity
Investigator-Initiated Research
Investigator-Initiated Research
CL008720
Research Activity
Research conceived and conducted by scientists in laboratories and clinics across the country and at NCI.
Epithelial Neutrophil-Activating Peptide 78 Measurement
Protein or Enzyme Type Measurement
C82010
Epithelial Neutrophil-Activating Peptide 78 Measurement
The determination of the amount of epithelial neutrophil-activating peptide 78 present in a sample.
Epithelial Neutrophil-Activating Peptide 78 Measurement
Epithelial Neutrophil-Activating Peptide 78 Measurement
owl:Class
Therapeutic or Preventive Procedure
Combined Pharmacological/Behavioral Treatment
Multimodality Therapy
Combined Pharmacological/Behavioral Treatments
owl:Class
Combined Pharmacological and Behavioral Treatment
Combined Pharmacological and Behavioral Treatment
C15983
CL003961
Combined Pharmacological and Behavioral Treatment
Combined Pharmacological and Behavioral Treatment
Pharmacological and behavioral interventions, such as the combined use of nicotine replacement and biofeedback, for the treatment of physiological addictions, such as nicotine. (NCI/TRIP)
Surgery for rectal cancer involving precise removal of an intact mesorectal envelope with tumor-free margins. Associated with local recurrence rates below 5% in clinical trials. (from Medscape)
Colon and Rectal Surgery
C16180
owl:Class
Therapeutic or Preventive Procedure
Total Mesorectal Excision
Total Mesorectal Excision
C1273428
TME
Total Mesorectal Excision
Procedure_Has_Completely_Excised_Anatomy only Rectum
Excision
Total Mesorectal Excision
CDISC SDTM Laboratory Test Terminology by Code
CDISC SEND Terminology
Clinical Data Interchange Standards Consortium Terminology
owl:Class
INTLK1
Interleukin 1 Measurement
Interleukin 1 Measurement
<def-definition>A measurement of the interleukin 1 in a biological specimen.</def-definition><def-source>CDISC</def-source>
Interleukin 1 Measurement
CDISC SDTM Laboratory Test Terminology by Name
Cytokine Measurement
Interleukin 1 Measurement
CDISC SDTM Terminology
Laboratory Procedure
Interleukin 1
CL384297
C74805
The determination of the amount of interleukin 1 present in a sample.
Carcinogen Screening
owl:Class
Carcinogen Screening
C15779
Carcinogen Screening
The concept does not refer to mutagenicity tests in bacterial and mammalian cell systems and epidemiologic studies.
CL000165
In vitro or in vivo testing to give a quantitative measure of tumor-inducing potency of the substance.
Research Activity
Cancer Research
Carcinogenesis, Screening
Carcinogen Screening
Therapeutic or Preventive Procedure
Ventricular Aneurysm Resection
Ventricular Aneurysm Resection
Cardiac Therapeutic Procedure
Ventricular Aneurysm Resection
Cardiovascular Surgical Procedure
Cardiac surgical procedure performed for the removal of an aneurysm from the ventricular wall.
C80451
owl:Class
Ventricular Aneurysm Resection
National Level Statistic
National Level Statistic
CL356327
National Level Statistic
National Level Statistic
Geographic Area Level Statistic
Quantitative Concept
C53186
owl:Class
Therapeutic Endoscopic Procedure
C1272853
C64958
Therapeutic Endoscopic Procedure
Therapeutic or Preventive Procedure
Therapeutic Endoscopic Procedure
Therapeutic Procedure
Therapeutic Endoscopic Procedure
owl:Class
Endoscopic Procedure
Mixed Lymphocyte Reaction Test
Mixed Lymphocyte Reaction Test
Immunology Test
Mixed Lymphocyte Culture
Mixed T Cells, B Cells
Mixed Lymphocyte Reaction Test
Mixed Lymphocyte Reaction Test
owl:Class
Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (usually measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with mitomycin C or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens.
C0023509
<def-source>MSH2001</def-source><def-definition>Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with MITOMYCIN or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens.</def-definition>
C16790
Laboratory Procedure
Research Activity
Biobehavioral Determinants of Tobacco Use and Addiction
Biobehavioral Determinants of Tobacco Use and Addiction
owl:Class
Studies of the links between biology and behavior aimed at identifying preexisting vulnerabilities to tobacco use and addiction. By determining how these vulnerabilities interact with sociocultural and psychological influences on tobacco use, and by improving the ability to assess risks quantitatively, more effective prevention and cessation interventions can be developed and tailored to those most likely to benefit from them.
Smoking and Health Research
Health Care Activity
Biobehavioral Determinants of Tobacco Use and Addiction
C16134
Biobehavioral Determinants of Tobacco Use and Addiction
CL014056
C15341
Tracheostomy
Creation of a surgical opening into the trachea.
Tracheostomy
Tracheostomy Procedure
Procedure_Has_Target_Anatomy only Trachea
<def-source>NCI-GLOSS</def-source><def-definition>(TRAY-kee-AHS-toe-mee) Surgery to create an opening (stoma) into the windpipe. The opening itself may also be called a tracheostomy.</def-definition>
tracheostomy
Tracheostomy
owl:Class
C0040590
Tracheostomy
Ostomy
Head and Neck Surgery
Therapeutic or Preventive Procedure
Incisional
Surgical Incision
incision
C15384
<def-source>NCI-GLOSS</def-source><def-definition>(in-SIH-zhun) A cut made in the body to perform surgery.</def-definition>
Health Care Activity
Surgical Incision
C0184898
Surgical Incision
Surgical Procedure by Method
Surgical Incision
Incision
owl:Class
Otomy
Period Method of Relative Survival Calculation
CL356507
Research Activity
Period Method of Relative Survival Calculation
Period Method of Relative Survival Calculation
Period Method
owl:Class
C53373
Period Method of Relative Survival Calculation
Survival Analysis Technique
Conceptual Entity
<def-source>CDISC</def-source><def-definition>The amount of drug administered to a patient or test subject at one time or the total quantity administered. [AMA Manual of Style] (CDISC Glossary)</def-definition>
A quantity of an agent (such as substance or energy) administered, taken, or absorbed at one time.
C0178602
CDISC SDTM Trial Summary Parameter Terminology by Code
CDISC SDTM Terminology
C25488
UCUM
Dose
<def-source>NCI-GLOSS</def-source><def-definition>The amount of medicine taken, or radiation given, at one time.</def-definition>
Dose per Administration
CDISC Observation Class Terminology
Dose
dose
DOSE
CDISC
Treatment Regimen
Doses
Dose
Dose
owl:Class
Clinical Data Interchange Standards Consortium Terminology
Dosage
{Dose}
DSTXT
UCUM Terminology
CDISC SDTM Trial Summary Parameter Terminology by Name
Affinity Chromatography
Immunoaffinity Chromatography
owl:Class
Immunoaffinity Chromatography
C0596751
Antibody Affinity Chromatography
Immunoaffinity Chromatography
Immunoaffinity Chromatography
Laboratory Procedure
Affinity chromatography using monoclonal or polyclonal antibodies, or (less commonly) antigens, as the immobilized binding phase.
C75519
CL052716
The process of classifying patients into a sequence of grades or ranks as part of the randomization process or for purposes of data analysis.
Stratification
Clinical Trials Design
Research Activity
C25689
Stratification
Stratification
Stratification
owl:Class
Enhance
To improve the quality of something; make better or more attractive.
Activity
Enhanced
owl:Class
C71607
Enhance
CL378356
Enhance
Enhance
Action
Enhancement
CL335326
Conceptual Entity
An addition to the length of something; the spreading of something into new regions.
Extension
owl:Class
Spread
Extension
C25270
Extension
Extension
Extended
Fecal Occult Blood Test
C74538
An antibody directed against either the hemoglobin protein or the globin portion is the basis for detection.
Immunochemical FOBT
Fecal Immunochemical Test
A fecal occult blood test that uses an immunological assay to detect hemoglobin in stool.
owl:Class
Fecal Immunochemical Test
Laboratory Procedure
Diagnostic Procedure
Fecal Immunochemical Test
FIT
CL384143
Fecal Immunochemical Test
iFOBT
Antiprolactin Therapy
Antiprolactin Therapy
Antiprolactin Therapy
C15540
Drug treatment to block the action of the female hormone prolactin.
Antiprolactin Therapy
Therapeutic or Preventive Procedure
Endocrine Drug Therapy
CL030467
owl:Class
owl:Class
Tissue Oxygen Measurement
CL365463
Tissue Oxygen Measurement
Physiologic Testing
C62673
Tissue Oxygen Measurement
Laboratory Procedure
Tissue Oxygen Measurement
Amino Acid Measurement
C81183
owl:Class
Amino Acid Measurement
Laboratory Procedure
The measurement of the amount of amino acids in a biologic specimen.
Chemistry Test
Amino Acid Measurement
Amino Acid Measurement
Mandibulectomy
Excision of Mandible
Mandibulectomy
Head and Neck Surgery
Mandibulectomy
Mandibulectomy
Procedure_Has_Excised_Anatomy only Mandible
Therapeutic or Preventive Procedure
CL354714
owl:Class
C51664
Surgery to remove part or all of the mandible.
CL322416
Laboratory Procedure
C38062
Flow cytometry used to examine and quantitate the constituents of the blood.
Blood Flow Cytometry
Flow Cytometry
Hematology Test
Blood Flow Cytometry
Blood Flow Cytometry
owl:Class
Blood Flow Cytometry
CL364941
Nanotechnology Techniques
owl:Class
Nanotechnology Techniques
Laboratory Procedure
Research Technique
C62318
Nanotechnology Techniques
Nanotechnology Techniques
Systematic procedures which are utilized for the manipulation of materials at the nanoscale (i.e., less than 100 nanometers).
Catheterization
Technique
A technique in which a hollow, flexible tube is used to drain body fluids or to introduce fluids into the body, or to examine or widen a narrowed vein or artery.
Catheterization
Health Care Activity
C38045
Catheterization
Catheterization
C0007430
owl:Class
Endocrine Test
Thyroxine Binding Globulin Protein Measurement
Thyroxine Binding Globulin Protein Measurement
CDISC SEND Terminology
CDISC SDTM Terminology
Thyroxine Binding Globulin
Clinical Data Interchange Standards Consortium Terminology
<def-source>CDISC</def-source><def-definition>A measurement of the thyroxine binding globulin protein in a biological specimen.</def-definition>
C0202233
Laboratory Procedure
owl:Class
CDISC SDTM Laboratory Test Terminology by Code
CDISC
CDISC SDTM Laboratory Test Terminology by Name
The determination of the amount of thyroxine binding globulin protein present in a sample.
C74746
Thyroxine Binding Globulin Protein Measurement
TBG
Protein or Enzyme Type Measurement
Thyroxine Binding Globulin Protein Measurement
Intervention Trial
Clinical Study by Design
Intervention Trial
CL014164
Intervention Trial
C16140
Intervention Trial
Research Activity
A pre-clinical or clinical study in human beings in which individuals are assigned by an investigator based on a protocol to receive specific interventions. The individuals are then followed and biomedical and/or health outcomes are assessed.
owl:Class
C68761
Pharmacogenetic Test
Laboratory Procedure
owl:Class
<def-source>FDA</def-source><def-definition>An assay intended to study interindividual variations in DNA sequence related to drug absorption and disposition (pharmacokinetics) or drug action (pharmacodynamics), including polymorphic variation(s) in the genes that encode the functions of transporters, metabolizing enzymes, receptors, and other proteins. From: Pharmacogenomic Data Submissions, FDA Guidance for Industry</def-definition>
Pharmacogenetic Test
Pharmacogenetic Test
Pharmacogenetic Test
Molecular Analysis
CL374483
Sodium to Creatinine Ratio Measurement
Sodium to Creatinine Ratio Measurement
owl:Class
Sodium to Creatinine Ratio Measurement
Sodium to Creatinine Ratio Measurement
NACREAT
Laboratory Procedure
The determination of the ratio of sodium compared to creatinine present in a sample. The measurement may be expressed as a ratio or percentage.
Clinical Data Interchange Standards Consortium Terminology
Sodium/Creatinine
CDISC SDTM Laboratory Test Terminology by Code
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Name
<def-definition>A relative measurement (ratio or percentage) of the sodium to creatinine in a biological specimen.</def-definition><def-source>CDISC</def-source>
Urine Protein Measurement
C79464
CDISC SDTM Terminology
CDISC SDTM Terminology
C64826
Clinical Data Interchange Standards Consortium Terminology
CL370261
Myelocytes/Leukocytes
CDISC SDTM Laboratory Test Terminology by Code
Myelocyte to Leukocyte Ratio
CDISC SDTM Laboratory Test Terminology by Name
CDISC
Myelocyte to Leukocyte Ratio
<def-definition>A relative measurement (ratio or percentage) of the myelocytes to leukocytes in a biological specimen.</def-definition><def-source>CDISC</def-source>
Laboratory Procedure
Myelocyte to Leukocyte Ratio
Blood Cell Count Ratio Measurement
CDISC SEND Terminology
MYCYLE
Myelocyte to Leukocyte Ratio
The determination of the ratio of myelocytes compared to leukocytes in a blood sample. The measurement may be expressed as a ratio or percentage.
owl:Class
owl:Class
Research Activity
C64268
A type of class comparison used when more than two classes are present in which each class is compared individually to each of the other classes. For example, Class A is compared to Class B, then compared to Class C; Class B is then compared to Class C, etc.
All-Pairs Comparison
Statistical Technique
All-Pairs Comparison
All-Pairs Comparison
All-Pairs Comparison
CL369236
Regulatory Assessment
Manufacturing Product Defect Manufacturing Defect With No Adverse Events
MANUFACTURING/PRODUCT DEFECT MANUFACTURING DEFECT WITH NO ADVERSE EVENTS
Intellectual Product
C82460
Manufacturing Product Defect Manufacturing Defect With No Adverse Events
Manufacturing Product Defect Manufacturing Defect With No Adverse Events
owl:Class
Manufacturing Product Defect Manufacturing Defect With No Adverse Events
owl:Class
C53344
Statistical Technique
Population-Based Statistic
Population-Based Statistic
Population-Based Statistic
Population-Based Statistic
CL356338
Quantitative Concept
One-Versus-All Comparison
C64269
One-Versus-All Comparison
owl:Class
Statistical Technique
Research Activity
A type of class comparison used when more than two classes are present in which each class is compared to the other classes as a group. For example Class A is compared to Classes B, C, and D; Class B is compared to Classes A, C, and D, etc.
CL369334
One-Versus-All Comparison
One-Versus-All Comparison
CL370560
Therapeutic or Preventive Procedure
Therapeutic Radioimmunoguided Surgery
C65015
Therapeutic Radioimmunoguided Surgery
Therapeutic Radioimmunoguided Surgery
Therapeutic Radioimmunoguided Surgery
Therapeutic Surgical Procedure
Radioimmunoguided Surgery
owl:Class
Tomographic examination of the kidney.
Radiography
Nephrotomography
C0203103
Diagnostic Procedure
C20176
owl:Class
Nephrotomography
Nephrotomography
Nephrotomography
owl:Class
CL376012
Use of nasogastric tubes after abdominal operation intended to hasten the return of bowel function, prevent pulmonary complications, diminish the risk of anastomotic leakage, increase patient comfort and shorten hospital stay.
Therapeutic or Preventive Procedure
Nasogastric Decompression
Nasogastric Decompression
Nasogastric Decompression
Nasogastric Decompression
C70910
Therapeutic Procedure
C15183
Chemotherapy, Antimetabolites
Treatment of cancer that utilizes antimetabolite substances to disrupt DNA, RNA, or protein synthesis.
owl:Class
Chemotherapy
Antimetabolite Chemotherapy
Antimetabolite Chemotherapy
Antimetabolite Chemotherapy
C0003377
Antimetabolite Chemotherapy
Chemotherapy, Cancer, Antimetabolites
Pharmacologic Substance
Transitional Care Planning
Supportive Care
CL030952
Health Care Activity
C15595
Transitional Care Planning
Transitional Care Planning
Transitional Care Planning
owl:Class
Alternative Medical Procedure
Alternative Medical Procedure
Therapeutic or Preventive Procedure
Alternative Medical Therapy
Complementary or Alternative Medical Procedure
CL336722
Treatment used instead of, or supplementary to, conventional Western-based practices. Alternative medicine includes treatments and practices such as acupuncture, holistic medicine, homeopathy, ayurveda, Chinese medicine, massage therapy, herbal therapy, and biofeedback.
C64386
Alternative Medical Procedure
Alternative Medical Procedure
owl:Class
Alternative Product Therapy
CLCREAT
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
Chloride to Creatinine Ratio Measurement
Chloride/Creatinine
Clinical Data Interchange Standards Consortium Terminology
owl:Class
Chloride to Creatinine Ratio Measurement
CDISC SDTM Laboratory Test Terminology by Name
Chloride to Creatinine Ratio Measurement
Chloride to Creatinine Ratio Measurement
Urine Protein Measurement
The determination of the ratio of chloride compared to creatinine present in a sample. The measurement may be expressed as a ratio or percentage.
CDISC SEND Terminology
C79440
Laboratory Procedure
<def-definition>A relative measurement (ratio or percentage) of the chloride to creatinine in a biological specimen.</def-definition><def-source>CDISC</def-source>
Therapeutic Procedure
Lifestyle Therapy
Therapeutic or Preventive Procedure
Lifestyle Therapy
CL001243
owl:Class
Lifestyle Therapy
Lifestyle Therapy
Therapy dealing with lifestyle management and includes: behavioral and dietary modifications, exercise, stress management, and addiction control. This therapy must be used as major adjunct to "standard care" or be applied as alternative treatment to conventional medicine practices.
C15900
Cytokine Measurement
Immunology Test
Cytokine Measurement
The determination of type and amount of cytokines in a sample.
C74804
CL384386
owl:Class
Cytokine Measurement
Laboratory Procedure
Cytokine Measurement
Hippuric Acid Measurement
Hippuric Acid Measurement
Hippuric Acid Measurement
The determination of the amount of hippuric acid present in a sample.
Chemistry Test
Hippuric Acid Measurement
owl:Class
C81949
Nutritional Requirements
C0028719
The protein, carbohydrates, fats and cofactors required to maintain a healthy body
owl:Class
Functional Concept
Diet and Nutrition
Nutritional Requirements
Nutritional Requirements
Nutritional Requirements
C15287
Therapeutic or Preventive Procedure
Immunotherapy
Anticytokine Therapy
C15544
Anti-Cytokine Therapy
Drug treatment to reduce the activity of cytokines, particulary to control inflammation in disease modalities.
Anti-Cytokine Therapy
Anti-Cytokine Therapy
Anti-Cytokine Therapy
owl:Class
CL030486
Toothbrushing
The act of cleaning teeth with a brush to remove plaque and prevent tooth decay.
Brushing
CL384859
owl:Class
Individual Behavior
Toothbrushing
Toothbrushing
Toothbrushing
Health Behavior
C63734
C15324
Self Care
Self-care
Self Care
Personal performance of activities or tasks traditionally performed by professional health care providers.
owl:Class
Action
Self Care
Selfcare
Self Care
Health Care Activity
C0036592
CDISC SDTM Terminology
owl:Class
CDISC
CDISC SDTM Laboratory Test Terminology by Code
Myeloblast Count
Myeloblast Count
Myeloblasts
<def-source>CDISC</def-source><def-definition>A measurement of the myeloblast cells per unit of a biological specimen.</def-definition>
Clinical Data Interchange Standards Consortium Terminology
Laboratory Procedure
Blast Count
Myeloblast Count
The determination of the number of myeloblast cells present in a sample.
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
Myeloblast Count
C0580952
C74632
MYBLA
Nanoparticle Application
Clinical Nanoparticle Application
Clinical Nanoparticle Application
owl:Class
Clinical Nanoparticle Application
Clinical Nanoparticle Application
C62310
CL364993
The use of nanoparticles for therapeutic applications in a clinical setting.
Activity
owl:Class
Massage Therapy
Massage
C15276
Massage Therapy
C0024875
Massage Therapy
Massage and Body Work
Therapeutic or Preventive Procedure
Massage Therapy
A therapeutic method of manipulation, methodical pressure, friction, and kneading of the body. (from Taber's)
Type I Collagen C-Telopeptide Measurement
Protein or Enzyme Type Measurement
Type I Collagen C-Telopeptide Measurement
The determination of the amount of the type I collagen C-telopeptide present in a sample.
Type I Collagen C-Telopeptide Measurement
owl:Class
C82038
Type I Collagen C-Telopeptide Measurement
EUS-FNA
CL371748
owl:Class
Endoscopic Ultrasound-Guided Fine-Needle Aspiration
C67287
Diagnostic Procedure
Fine-Needle Aspiration
Endoscopic Ultrasound-Guided Fine-Needle Aspiration
Endoscopic Ultrasound-Guided Fine-Needle Aspiration
Endoscopic Ultrasound-Guided Fine-Needle Aspiration
Diagnostic Endoscopic Procedure
C81198
Statistical Imputation
The substitution of missing data with the most recent data collected that is not missing.
Quantitative Concept
owl:Class
Last Observation Carried Forward Imputation Technique
Last Observation Carried Forward Imputation Technique
Last Observation Carried Forward Imputation Technique
Last Observation Carried Forward Imputation Technique
Research Activity
Vaccine Research
C26030
owl:Class
CL053955
Vaccine Production
Vaccine Production
Vaccine Production
Vaccine Production
Nutrition, Carbohydrates
Nutrition, Carbohydrates
Nutrition, Dietary Components
Nutrition, Carbohydrates
Research Activity
owl:Class
Role of carbohydrates in cancer causation or prevention and in general health.
Nutrition, Carbohydrates
Carbohydrate Nutrition
CL357870
C15223
Reinfusion
C50820
Patient Code (Appendix B)
Patient Problem Codes FDA CDRH
CL355999
Reinfusion Procedure
Reinfusion Procedure
Reinfusion Procedure
Reinfusion Procedure
owl:Class
The infusion of autogenic body fluid that has previously been withdrawn from the patient.
FDA
Infusion Procedure
Health Care Activity
Procedure_Has_Partially_Excised_Anatomy only Breast
Therapeutic or Preventive Procedure
Surgery performed to reduce the size of the breast.
Mammoplasty
CL355994
owl:Class
Reduction Mammoplasty
C51615
Procedure_Has_Partially_Excised_Anatomy only 'Adipose Tissue'
Reduction Mammoplasty
Reduction Mammoplasty
Reduction Mammoplasty
Procedure_Has_Partially_Excised_Anatomy only 'Mammary Gland'
CL387852
C78869
EDX
owl:Class
Energy Dispersive Spectroscopy
Energy Dispersive Spectroscopy
A type of spectroscopy that analyzes the X-rays emitted by a sample after exposure to a focused beam of high energy electromagnetic radiation to determine the atomic composition of a region of a sample.
Spectroscopy
EDS
Energy Dispersive Spectroscopy
Research Activity
Laboratory Procedure
Energy Dispersive Spectroscopy
Energy Dispersive X-Ray Spectroscopy
Screening Generic
Screening Generic
Diagnostic Procedure
CL343818
Screening Generic
A systematic examination or assessment.
Disease Screening
owl:Class
C48261
Screening Generic
Complement C3b Measurement
Complement C3b Measurement
Complement Measurement
owl:Class
The determination of the amount of complement C3b present in a sample.
C80176
Complement C3b Measurement
Laboratory Procedure
Complement C3b Measurement
CDISC SEND Terminology
Lactate Dehydrogenase Isoenzyme 3 Measurement
LDH Isoenzyme 3
LDH3
CL384323
<def-definition>A measurement of the lactate dehydrogenase isoenzyme 3 in a biological specimen.</def-definition><def-source>CDISC</def-source>
Lactate Dehydrogenase Isoenzyme 3 Measurement
owl:Class
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Name
Lactate Dehydrogenase Isoenzyme 3 Measurement
Protein or Enzyme Type Measurement
C74889
Lactate Dehydrogenase Isoenzyme 3 Measurement
Clinical Data Interchange Standards Consortium Terminology
The determination of the lactate dehydrogenase isoenzyme 3 present in a sample.
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
Progestin Therapy
Progestin Therapy
Therapeutic or Preventive Procedure
owl:Class
Endocrine Drug Therapy
C0279495
Progestin Therapy
C15484
Progestin Therapy
Pericardiocentesis
C52010
Pericardiocentesis
Therapeutic or Preventive Procedure
Pericardiocentesis
Paracentesis
Pericardiocentesis
owl:Class
Diagnostic Procedure
CL354150
Laparoscopy
Diagnostic Laparoscopy
Diagnostic Laparoscopy
Diagnostic Laparoscopy
Diagnostic Laparoscopy
C1880304
Diagnostic Endoscopic Procedure
owl:Class
Diagnostic Procedure
C64946
A method to normalize arrays in an AffyBatch using an invariant set, as defined in documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html
Statistical Technique
Bioconductor caAffy Invariant Set Normalization
Bioconductor caAffy Invariant Set Normalization
CL369465
Activity
owl:Class
Bioconductor caAffy Invariant Set Normalization
Bioconductor caAffy Invariant Set Normalization
C63932
C0200069
Fertility Study
Fertility Study
Fertility Study
Fertility Study
Research Activity
C15413
Population Research
owl:Class
CL035535
Genetic Testing
Mutation Carrier Screening
Laboratory Procedure
Mutation Carrier Screening
Diagnostic Procedure
Mutation Carrier Screening
owl:Class
Mutation Carrier Screening
C62694
CDISC SDTM Laboratory Test Terminology by Code
Calcium Carbonate Crystal Measurement
Calcium Carbonate Crystal Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the calcium carbonate crystals present in a biological specimen.</def-definition>
CL384768
Laboratory Procedure
CDISC SDTM Terminology
Crystal Growth Measurement
CDISC SDTM Laboratory Test Terminology by Name
C74669
CDISC SEND Terminology
Clinical Data Interchange Standards Consortium Terminology
Calcium Carbonate Crystal Measurement
CYCACAR
Calcium Carbonate Crystal Measurement
CDISC
The determination of the amount of calcium carbonate crystals present in a sample.
Calcium Carbonate Crystals
owl:Class
C0033144
Primary Prevention
Prevention of disease or mental disorders in susceptible individuals or populations through promotion of health, including mental health, and specific protection, as in immunization, as distinguished from the prevention of complications or after-effects of existing disease.
owl:Class
Therapeutic or Preventive Procedure
Preventive Intervention
Primary Prevention
Prevention, Primary
Primary Prevention
C15306
Primary Prevention
Hormone Measurement
Serum Pregnany Test
Serum HCG Measurement
Serum Human Chorionic Gonadotropin Measurement
Laboratory Procedure
A quantitative measurement of the amount of human chorionic gonadotropin present in a sample of serum.
Serum HCG Measurement
Serum HCG Measurement
CL383697
Serum HCG Measurement
owl:Class
C73495
Action
C49156
Comparison
Comparison
Compare
Compared
Comparison
The examination of two or more people or things in order to detect similarities and differences.
CL353823
Activity
Comparison
owl:Class
Sampling Method
Sampling Method
Activity
Sampling Method
C0449370
owl:Class
Statistical Technique
C71492
Sampling Design
Sampling Technique
Sampling Method
Post Translational Modification Analysis
C18951
owl:Class
Post Translational Modification Analysis
Post Translational Modification Analysis
Protein Analysis
Laboratory procedures used for the analysis of the processing events of a protein after its translation from messenger RNA in order to gain insight into biological function. These include mass spectrometric peptide sequencing and analysis technologies.
Laboratory Procedure
CL000737
Post Translational Modification Analysis
Hypophysectomy
Hypophysis Excision
Excision of the Pituitary Gland+B3297
owl:Class
Hypophysectomy
Head and Neck Surgery
Hypophysectomy
Excision of the Hypophysis
Hypophysis Cerebri Excision
Surgical removal of part or all of the pituitary gland.
Therapeutic or Preventive Procedure
C0020632
Surgical excision of the Hypophysis cerebri. Often used in the treatment of metastatic bone pain, estrogen positive breast cancer, and prostate cancer pain. (Taber's)
Procedure_Has_Excised_Anatomy only 'Pituitary Gland'
Hypophysectomy
Pituitary Gland Excision
Pituitectomy
Excision of the Pituitary Gland
Ablative Endocrine Surgery
C15255
Mass Spectrometry
C17156
An analytical technique wherein ions are separate according to their ratio of charge to mass. From the mass spectrum produced, the atomic weight of the particle can be deduced.
Mass Spectrum
Laboratory Procedure
Mass Spectrometry
Photometry/Spectrum Analysis, Mass
Mass Spectrometry
C0037813
MS
owl:Class
Mass Spectrometry
Mass Spec
Spectrometry
C51611
Rectosigmoidectomy
Rectosigmoidectomy
owl:Class
Procedure_Has_Excised_Anatomy only Rectum
Rectosigmoidectomy
Therapeutic or Preventive Procedure
Colon and Rectal Surgery
CL355993
Procedure_Has_Excised_Anatomy only 'Sigmoid Colon'
Surgical removal part or all of the sigmoid colon, and part or all of the rectum.
Rectosigmoidectomy
Low-LET Cobalt-60 Gamma Ray Therapy
owl:Class
CL029004
Low-LET Cobalt-60 Gamma Ray Therapy
Radiation Therapy
therapy, low-LET cobalt-60 gamma ray
Low-LET Cobalt-60 Gamma Ray Therapy
Therapeutic or Preventive Procedure
Low-LET Cobalt-60 Gamma Ray Therapy
C15443
Average Linkage Clustering
C65183
Average Linkage
Average Linkage Cluster Analysis
Research Activity
Average Linkage Cluster Analysis
Average Linkage Cluster Analysis
CL371048
Hierarchical Clustering
owl:Class
A clustering method that determines the mean distance between all possible inter- or intra-cluster pairs.
Average Linkage Cluster Analysis
Clinical Data Interchange Standards Consortium Terminology
PHARMACOECONOMIC
Trial Type
CL323590
<def-source>CDISC</def-source><def-definition>A study that assesses the value associated with a given drug in therapeutic and economic terms. This type of study is multidisciplinary in nature and takes into consideration the social and economic costs (resource utilization costs including direct, indirect, and intangible costs) of drug therapy in addition to its direct therapeutic benefits. Analyses relate the difference in therapeutic benefits to the difference in costs between treatment alternatives. (NCI)</def-definition>
CDISC
Pharmacoeconomic Study
Research Activity
CDISC SDTM Terminology
owl:Class
Pharmacoeconomic Study
A study that assesses the value associated with a given drug in therapeutic and economic terms. This type of study is multidisciplinary in nature and takes into consideration the social and economic costs (resource utilization costs including direct, indirect, and intangible costs) of drug therapy in addition to its direct therapeutic benefits. Analyses relate the difference in therapeutic benefits to the difference in costs between treatment alternatives.
Pharmacoeconomic Study
C39493
Pharmacoeconomic Study
CDISC SDTM Trial Type Terminology
owl:Class
Activity
Follow
Follow
CL370612
Follow
C64950
Instruction Imperative
Follow
Therapeutic or Preventive Procedure
Billroth II Procedure
Billroth II Procedure
Procedure_Has_Target_Anatomy only Jejunum
Billroth II Procedure
Surgical removal of the lower part of the stomach with end-to-end anastomosis of the remaining segment of the stomach with the jejunum; in this procedure the duodenum is closed off.
C51582
Procedure_Has_Target_Anatomy only Duodenum
Procedure_Has_Completely_Excised_Anatomy only 'Antrum Pylori'
Billroth II Procedure
CL354987
Procedure_Has_Completely_Excised_Anatomy only 'Pyloric Sphincter'
owl:Class
Subtotal Gastrectomy
Procedure_Has_Partially_Excised_Anatomy only Stomach
Low Fat, High Fiber Diet
Qualitative Concept
Diet
C16164
Low Fat, High Fiber Diet
Low Fat, High Fiber Diet
CL014531
Low Fat, High Fiber Diet
owl:Class
owl:Class
Diagnostic Procedure
C1537007
Diffusion Tensor Imaging
C64862
Diffusion Tensor Imaging
Diffusion Tensor Imaging
Diffusion Tensor Imaging
Magnetic Resonance Imaging
Conformation Dependent Mutation Detection
Dideoxy Fingerprinting
owl:Class
Dideoxy Fingerprinting
C19230
A variation of SSCP analysis in which the DNA fragments are generated by chain terminating sequencing reactions. Can be more sensitive due to the increased number of fragments, only a small number of which might display an altered migration.
CL003145
Laboratory Procedure
Dideoxy Fingerprinting
Dideoxy Fingerprinting
Studies identifying, testing, and implementing interventions among groups of individuals that are designed to prevent the initiation of a substance, such as tobacco or alcohol.
Research Activity
Prevention Research
Prevention Research
Prevention Research
Prevention Research
owl:Class
Research Activity
C15711
C0679695
C74735
BNP
<def-source>CDISC</def-source><def-definition>A measurement of the brain (B-type) natriuretic peptide in a biological specimen.</def-definition>
CDISC
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
Brain Natriuretic Peptide Measurement
owl:Class
Brain Natriuretic Peptide
The determination of the amount of brain natriuretic peptide present in a sample.
Laboratory Procedure
Brain Natriuretic Peptide Measurement
Protein or Enzyme Type Measurement
Brain Natriuretic Peptide Measurement
CDISC SDTM Terminology
Brain Natriuretic Peptide Measurement
CDISC SDTM Laboratory Test Terminology by Name
C1095989
B-Type Natriuretic Peptide
CDISC SEND Terminology
Surgical Procedure by Method
Thoracoscopic Surgery
C0751551
Procedure_Has_Target_Anatomy only 'Thoracic Cavity'
Therapeutic or Preventive Procedure
Thoracoscopic Surgery
C15726
Thoracic Surgical Procedure
Thoracoscopic Surgery
owl:Class
Thoracoscopic Surgery
Diagnostic Procedure
The determination of the amount of interleukin 17 present in a sample.
CDISC SDTM Laboratory Test Terminology by Code
C74813
Clinical Data Interchange Standards Consortium Terminology
INTLK17
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Terminology
Interleukin 17 Measurement
Cytokine Measurement
Interleukin 17 Measurement
<def-definition>A measurement of the interleukin 17 in a biological specimen.</def-definition><def-source>CDISC</def-source>
Interleukin 17
CDISC SEND Terminology
Interleukin 17 Measurement
CL384294
Interleukin 17 Measurement
owl:Class
Laboratory Procedure
Mutation Analysis
BRCA2 Status Determination
owl:Class
BRCA2 Mutation Analysis
BRCA2 Mutation Analysis
BRCA2 Mutation Analysis
Laboratory Procedure
C80499
BRCA2 Mutation Analysis
Worst Case Imputation Technique
Worst Case Imputation Technique
owl:Class
Statistical Imputation
Worst Case Imputation Technique
Quantitative Concept
C81203
The substitution of missing data with the value that represents the worst possible outcome.
Worst Case Imputation Technique
Impute
Statistical Imputation
Statistical Imputation
Statistical Imputation
C80304
Statistical Imputation
owl:Class
Imputation
Imputed
The substitution of some value for a missing data point or a missing component of a data point.
Statistical Technique
Quantitative Concept
C82018
Protein or Enzyme Type Measurement
Granulocyte Colony Stimulating Factor Measurement
The determination of the amount of granulocyte colony stimulating factor present in a sample.
Granulocyte Colony Stimulating Factor Measurement
Granulocyte Colony Stimulating Factor Measurement
Granulocyte Colony Stimulating Factor Measurement
owl:Class
cecostomy
Colon and Rectal Surgery
cecostomy
Therapeutic or Preventive Procedure
Surgical creation of an opening in the cecum.
Procedure_Has_Target_Anatomy only Cecum
owl:Class
cecostomy
C0007530
C15200
cecostomy
Research Activity
C20066
CL015637
Microfabrication
Microfabrication
Microtechnique
owl:Class
Microfabrication
The processing techniques, such as deposition, etching, and patterning, that are utilized to produce miniaturized structures and devices with feature sizes and resolution in the micron domain. Uses a combination of micromachining and integrated circuit fabrication technology. (from U. Louisville course description)
Microfabrication
Gastrectomy with Esophagojejunostomy
Procedure_Has_Target_Anatomy only Jejunum
Procedure_Has_Completely_Excised_Anatomy only Stomach
Surgical removal of the stomach with end to end anastomosis of the esophagus with the duodenum.
Therapeutic or Preventive Procedure
CL320062
Gastrectomy with Esophagojejunostomy
Gastrectomy with Esophagojejunostomy
Gastrectomy with Esophagojejunostomy
Gastrectomy
C29890
owl:Class
Procedure_Has_Target_Anatomy only Esophagus
Partial Maxillectomy
Maxillectomy
Surgery to remove part of the maxilla.
Partial Maxillectomy
owl:Class
Partial Maxillectomy
Therapeutic or Preventive Procedure
Procedure_Has_Partially_Excised_Anatomy only Maxilla
C51657
Partial Maxillectomy
CL354139
Wright-Giemsa Staining Method
C23041
Laboratory Procedure
Routine Histology Staining Method
Geimsa is a polychromatic stain that permits the differentiation of cells present in hematopoietic tissues and for the demonstration of certain microorganisms. It is used for the detection of helicobacter Pylori. The H. Pylori and nuclei stain dark blue and cytoplasm stain pink with this stain (From BioGenex).
Wright-Giemsa Staining
C0523212
Wright-Giemsa Staining Method
Wright-Giemsa Staining Method
Wright-Giemsa Staining Method
Wright-Giemsa Staining Method
owl:Class
Therapeutic or Preventive Procedure
Surgical removal of part or all of the clavicle.
Resection of Clavicle
Thoracic Surgical Procedure
Procedure_Has_Excised_Anatomy only Clavicle
Resection of Clavicle
owl:Class
Resection of Clavicle
C51789
CL355453
Resection of Clavicle
Ovarian Ablation
<def-source>NCI-GLOSS</def-source><def-definition>Surgery, radiation therapy, or a drug treatment to stop the functioning of the ovaries.</def-definition>
ovarian suppression
Ovarian Ablation
C15691
owl:Class
Ovarian Ablation
C0677922
ovarian ablation
Therapeutic or Preventive Procedure
Ovarian Ablation
Ablation Therapy
Therapeutic or Preventive Procedure
Active Immunization
Deliberate stimulation of a host's immune response via administration of antigens or immunologic adjuvants.
C15416
owl:Class
Immunization
Active Immunization
C0205991
Active Immunization
Active Immunization
Public Health Applications Research
Public Health Applications
C16146
owl:Class
Public Health Applications Research
Cancer Research
The Public Health Applications Branch conducts a variety of cancer prevention projects that widely disseminate research results, and test the effectiveness of interventions in large populations. These projects almost always involve collaboration with community and state organizations involved in health care delivery and public health. Branch activities cover the topics of tobacco use, cancer screening, skin cancer prevention, and diet. Public and private policies related to cancer prevention are addressed in many projects. (Cancer Prevention Fellowship Program)
Involvement of the public health community (i.e., state and local health departments) in the development of initiatives and programs for cancer risk reduction, and cancer prevention and control. Primary interest is in 1) research on interventions in cancer control in public health settings and 2) the dissemination and application of research findings among public health agencies and professionals.
Public Health Applications Research
Public Health Applications Research
Research Activity
CL014316
C0036776
Serum Alkaline Phosphatase Measurement
Alkaline Phosphatase Measurement
C61016
Serum Alkaline Phosphatase Measurement
Serum Alkaline Phosphatase Measurement
A quantitative measurement of the amount of alkaline phosphatase present in a sample of serum.
owl:Class
Serum Alkaline Phosphatase Measurement
Laboratory Procedure
Serum Chemistry Measurement
C0202344
C75364
owl:Class
Barbiturate Drug Class Measurement
Butabarbital Measurement
Laboratory Procedure
Butabarbital Measurement
Butabarbital Measurement
The determination of the amount of butabarbital present in a sample.
Butabarbital Measurement
Conventional Surgery
Therapeutic Conventional Surgery
owl:Class
Therapeutic Conventional Surgery
Therapeutic Conventional Surgery
Therapeutic Surgical Procedure
C65008
CL370552
Therapeutic or Preventive Procedure
Therapeutic Conventional Surgery
DIED - EUTHANIZED
Terminal Sedation
Terminal Sedation
Mercy Killing
The purposeful use of morphine, other opiates, or other pharmaceuticals at doses adequate to end life functions.
Palliative Therapy
Euthanasia
Terminal Sedation
owl:Class
Assisted Suicide
C21115
Terminal Sedation
Therapeutic or Preventive Procedure
C0162665
Normal Distribution
owl:Class
Normal Distribution
Quantitative Concept
Normal Distribution
C0332617
A family of probability density functions whose mean, median and mode are identical. The function generates a symmetrical curve, whose position and shape is determined by its location and scale parameters, the mean and standard deviation respectively. The standard normal distribution has a location parameter of 0 and a scale parameter of 1.
Normal Distribution
Continuous Distribution
C53215
Gaussian Distribution
CDISC SDTM Laboratory Test Terminology by Code
A quantitative measurement of the amount of urobilinogen present in a sample.
CDISC SDTM Terminology
Urobilinogen Measurement
UROBIL
<def-source>CDISC</def-source><def-definition>A measurement of the urobilinogen in a biological specimen.</def-definition>
Urobilinogen
CDISC SEND Terminology
Urobilinogen Measurement
Urobilinogen Measurement
CDISC
Clinical Data Interchange Standards Consortium Terminology
owl:Class
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
Urine Chemistry Measurement
C64816
C0202241
Urobilinogen Measurement
C0008395
Nutrition, Cholesterol
Nutrition, Cholesterol
owl:Class
Nutrition, Cholesterol
Lipid Nutrition, Cholesterol
Research Activity
Role of cholesterol in cancer causation or prevention and in general health.
Nutrition, Cholesterol
C15205
Nutrition, Dietary Components
Bypass
Procedure_Has_Target_Anatomy only Heart
C0010055
C51998
Coronary Artery Bypass Graft
Cardiovascular Surgical Procedure
Coronary Artery Bypass Surgery
Therapeutic or Preventive Procedure
owl:Class
Heart Bypass
Procedure_Has_Target_Anatomy only 'Coronary Artery'
Coronary Artery Bypass Surgery
Coronary Artery Bypass Surgery
Surgery performed to bypass partially or completely occluded coronary arteries, thereby increasing the blood supply of the heart.
Cardiac Therapeutic Procedure
Coronary Artery Bypass Grafting
Coronary Artery Bypass Surgery
CABG
Coombs Test
Coombs Test
Coombs
Hematology Test
owl:Class
C0009961
C25163
Coombs Test
Coombs Test
Diagnostic Procedure
Hemagglutination test in which Coombs' reagent (antiglobulin, or anti-human globulin rabbit immune serum) is added to detect incomplete (non-agglutinating, univalent, blocking) antibodies coating erythrocytes. The direct test is applied to red cells which have been coated with antibody in vivo (e.g., in hemolytic disease of newborn, autoimmune hemolytic anemia, and transfusion reactions). The indirect test is applied to serum to detect the presence of antibody (e.g., in detection of incompatibility in cross-matching tests, detection and identification of irregular antibodies, and in detection of antibodies not identifiable by other means). (MeSH)
Laboratory Procedure
FPLC
Fast Protein Liquid Chromatography
owl:Class
Fast Protein Liquid Chromatography
C80368
Liquid Chromatography
Fast Protein Liquid Chromatography
Laboratory Procedure
Fast Protein Liquid Chromatography
A type of liquid chromatography where the solvent flow and composition is controlled by pumps.
Cigar Smoking
CL008594
Cigar Smoking
Tobacco Smoking
C19702
Individual Behavior
owl:Class
Cigar Smoking
Cigar Smoking
owl:Class
C74890
LDH4
CDISC SDTM Terminology
CL384324
Lactate Dehydrogenase Isoenzyme 4 Measurement
Protein or Enzyme Type Measurement
Lactate Dehydrogenase Isoenzyme 4 Measurement
The determination of the lactate dehydrogenase isoenzyme 4 present in a sample.
Clinical Data Interchange Standards Consortium Terminology
Lactate Dehydrogenase Isoenzyme 4 Measurement
CDISC SDTM Laboratory Test Terminology by Code
<def-definition>A measurement of the lactate dehydrogenase isoenzyme 4 in a biological specimen.</def-definition><def-source>CDISC</def-source>
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Name
Lactate Dehydrogenase Isoenzyme 4 Measurement
LDH Isoenzyme 4
CDISC SEND Terminology
C28257
Staging
<def-source>NCI-GLOSS</def-source><def-definition>A method used to determine the stage of cancer. Tissue samples are removed during surgery or a biopsy. The stage is determined based on how the cells in the samples look under a microscope.</def-definition>
Pathological Staging
Pathological Staging
owl:Class
Classification
An examination that is performed to determine the extent of the spread of cancer based on histopathologic examination of one or more pathology specimens. Pathologic staging uses evidence acquired during the process of clinical staging, supplemented by histopathologic examination of surgical specimens.
pathological staging
Pathological Staging
C0443276
Pathological Staging
Action
The activity of looking thoroughly in order to find something or someone; an operation that determines whether one or more of a set of items has a specified property.
Search
Search
Search
Search
CL357383
C54117
Activity
Searched
owl:Class
C1264641
Percentile
Any of the 99 numbered points that divide an ordered set of scores into 100 parts each of which contains one-hundredth of the total.
C48919
Statistical Technique
Percentile
Percentile
Qualitative Concept
Percentile
owl:Class
Therapeutic or Preventive Procedure
C21097
Sedation
Sedation
Sedation
C0344106
FDA
Patient Problem Codes FDA CDRH
The process of allaying nervous excitement or the state of being calmed. (Taber's)
owl:Class
Anesthesia Procedure
Sedation
Patient Code (Appendix B)
Microalbumin/Creatinine Ratio
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Terminology
CDISC
owl:Class
Albumin To Creatinine Protein Ratio Measurement
C0486293
Albumin To Creatinine Protein Ratio Measurement
Urine Protein Measurement
ALBCREAT
Clinical Data Interchange Standards Consortium Terminology
<def-source>CDISC</def-source><def-definition>A relative measurement (ratio or percentage) of the albumin to the creatinine in a urine specimen.</def-definition>
Albumin To Creatinine Protein Ratio Measurement
Albumin To Creatinine Protein Ratio Measurement
C74761
CDISC SDTM Laboratory Test Terminology by Code
CDISC SEND Terminology
Albumin/Creatinine
The determination of the ratio of albumin compared to creatinine protein present in a urine sample. The measurement may be expressed as a ratio or percentage.
C0282462
Phase IV Trial
4
Phase IV Clinical Trials
Phase IV Trial
CDISC SDTM Terminology
CDISC SDTM Trial Phase Terminology
Phase IV Trial
A randomized, controlled trial that is designed to evaluate the long-term safety and efficacy of a drug for a given indication. Often they are designed to study side effects that may have become apparent after the phase III study was completed.
Clinical Data Interchange Standards Consortium Terminology
Phase IV Study
phase IV trial
Research Activity
CDISC
Trial Phase 4
<def-source>NCI-GLOSS</def-source><def-definition>After a treatment has been approved and is being marketed, it is studied in a phase IV trial to evaluate side effects that were not apparent in the phase III trial. Thousands of people are involved in a phase IV trial.</def-definition>
C15603
Clinical Study by Phase
<def-source>CDISC</def-source><def-definition>Phase 4. Postmarketing (Phase 4) studies to delineate additional information about the drug's risks, benefits, and optimal use that may be requested by regulatory authorities in conjunction with marketing approval. NOTE: These studies could include, but would not be limited to, studying different doses or schedules of administration than were used in Phase 2 studies, use of the drug in other patient populations or other stages of the disease, or use of the drug over a longer period of time. [After FDA CDER Handbook, ICH E8] (CDISC glossary)</def-definition>
owl:Class
Phase 4 Study
Phase IV Trial
Clinical Trials, Phase IV
Urethrostomy
Urostomy
C0194560
Procedure_Has_Target_Anatomy only Urethra
C15398
Urethrostomy
owl:Class
Therapeutic or Preventive Procedure
Urethrostomy
Urethrostomy
External Beam RT
External Radiation Therapy
External Beam Radiation Therapy
C15751
External Beam Radiation Therapy
External Beam Radiation Therapy
Therapeutic or Preventive Procedure
CL052154
external-beam radiation
owl:Class
External Beam Radiation Therapy
<def-source>NCI-GLOSS</def-source><def-definition>(ray-dee-AY-shun) Radiation therapy that uses a machine to aim high-energy rays at the cancer.</def-definition>
Definitive Radiation Therapy
Androstenedione Measurement
C74843
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Name
ANDSTNDN
The determination of the amount of androstenedione hormone present in a sample.
C0337432
CDISC SDTM Laboratory Test Terminology by Code
Androstenedione Measurement
owl:Class
Androstenedione Measurement
Clinical Data Interchange Standards Consortium Terminology
Laboratory Procedure
4-Androstenedione
Androstenedione
CDISC SDTM Terminology
<def-definition>A measurement of the androstenedione hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
Hormone Measurement
Androstenedione Measurement
Excision of Skin or Subcutaneous Tissue
Excision of Skin or Subcutaneous Tissue
CL353904
Therapeutic or Preventive Procedure
C51936
owl:Class
Skin Excision
Excision of Skin or Subcutaneous Tissue
Excision of Skin or Subcutaneous Tissue
Scanning Probe Microscopy
SPM
Atomic Resolution Microscopy
Atomic Resolution Microscopy
Scanning probe microscopy types include atomic force microscopy, magnetic force microscopy, scanning tunneling microscopy and force modulation microscopy.
Microscopy
C20346
Several related technologies for imaging and measuring surfaces on a fine scale, down to the level of molecules and groups of atoms. These technologies share the concept of scanning an extremely sharp tip (3-50 nm radius of curvature) across the object surface. The tip is mounted on a flexible cantilever, allowing the tip to follow the surface profile. When the tip moves in proximity to the investigated object, forces of interaction between the tip and the surface influence the movement of the cantilever. Various interactions can be studied depending on the specific mechanics of the probe. Specialized sensors detect and record the movements of the cantilever, providing an image with resolution at the atomic level.
Atomic Scale Microscopy
Atomic Resolution Microscopy
CL026532
owl:Class
Atomic Resolution Microscopy
Laboratory Procedure
CL353461
owl:Class
Intestine Resection
Intestine Resection
Intestine Resection
Digestive System Surgery
Procedure_Has_Excised_Anatomy only Intestine
Therapeutic or Preventive Procedure
Surgical removal of part or all of the intestine.
C51652
Intestine Resection
Bowel Resection
Poisson Distribution
Discrete Distribution
Quantitative Concept
C53212
C0032347
Poisson Distribution
owl:Class
Poisson Distribution
Poisson Distribution
Statistical Technique
Central Minus
CL371500
The average cell intensity for the nine probe cells that compose the cross at the center of the antisense probe array.
Central -
C67055
Central M
Central Minus
owl:Class
Central Minus
Central Minus
Activity
Food Safety
Food Safety
Research Activity
Food Safety
CL053944
C26037
Food Safety
owl:Class
Biomedical Occupation or Discipline
Lumbar Puncture
C0037943
Lumbar Puncture
Spinal Tap
Aspiration
owl:Class
C15327
Lumbar Puncture
lumbar puncture
Diagnostic Procedure
<def-source>NCI-GLOSS</def-source><def-definition>A procedure in which a needle is put into the lower part of the spinal column to collect cerebrospinal fluid or to give anticancer drugs intrathecally.</def-definition>
LP
spinal tap
Lumbar Puncture
Low Dose Radiation
Radiation Therapy
owl:Class
Low Dose Radiation
Low Dose Radiation
Quantitative Concept
C15811
CL000510
Therapeutic or Preventive Procedure
Low Dose Radiation
C46078
Endoscopic Ultrasound
CL342242
An ultrasound administered by using a tube containing flexible fibre optic wires that allows for the analysis of tissues inside the body. Ultrasound technology utilizes high frequency waves and their echoes to produce an image. 2005
Endoscopic Ultrasound
Endoscopic Ultrasound
Endoscopic Ultrasound
Diagnostic Ultrasound
owl:Class
Diagnostic Procedure
Therapeutic or Preventive Procedure
Fertility Assessment and Management
fertility management/assessment
Fertility Assessment and Management
CL030004
Fertility Assessment and Management
Supportive Care
Fertility Assessment and Management
C15516
owl:Class
CD4 Expressing T Cell Count
owl:Class
Lymphocyte Count
CD4
<def-source>CDISC</def-source><def-definition>A count of the CD4 T cells per unit of a biological specimen.</def-definition>
CD4 Expressing T Cell Count
CD4 Expressing T Cell Count
CDISC
C74608
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Name
CL384376
Laboratory Procedure
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
CD4 Expressing T Cell Count
The determination of the number of CD4 expressing T cells present in a sample.
CDISC SEND Terminology
Mortality Map
owl:Class
Mortality Map
Intellectual Product
Mortality Map
CL008189
Mortality Map
C16066
Cancer Surveillance Project
A visual representation of the national cancer burden. These maps display cancer mortality data by county and state economic regions across the country. They are color coded to distinguish between regions with high, intermediate, and low rates of cancer mortality.
owl:Class
Allogeneic Hematopoietic Stem Cell Transplantation
CL365778
Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation
Therapeutic or Preventive Procedure
Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation
Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation
C62714
Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation
Laboratory Procedure
Gelatin Substrate Zymography
Molecular Biology Research Technique
Sodium Dodecylsulfate-Polyacrylamide Gel Electrophoresis
Gelatin Zymography
C19835
Gelatin Zymography
Gelatin Zymography
An SDS-PAGE based procedure used to identify matrix metalloproteinases.
Gelatin Zymography
owl:Class
CL008959
owl:Class
CDISC SDTM Laboratory Test Terminology by Code
Cellular Cast Measurement
Epithelial-Cast Measurement
CDISC SDTM Laboratory Test Terminology by Name
Epithelial-Cast Measurement
Epithelial Casts
<def-source>CDISC</def-source><def-definition>A measurement of the epithelial cell casts present in a urine specimen.</def-definition>
CDISC
Epithelial-Cast Measurement
CDISC SEND Terminology
CSEPI
Clinical Data Interchange Standards Consortium Terminology
C74779
Epithelial-Cast Measurement
CL384387
CDISC SDTM Terminology
Laboratory Procedure
The determination of the number of epithelial casts present in a urine sample.
owl:Class
Vaccine Research
Research focusing on any aspect of vaccine research, development, testing, etc.
Research Activity
C26028
Vaccine Research
CL053954
Vaccine Research
Biomedical Research
Vaccine Research
Cell Culture
owl:Class
Secondary Cell Culture
Laboratory Procedure
Secondary Cell Culture
Secondary Cell Culture
C20215
Secondary Cell Culture
CL026132
Propagation of cell that have already been established in culture.
CDISC SDTM Laboratory Test Terminology by Code
HIV-1 Antibody
CDISC
C74713
<def-source>CDISC</def-source><def-definition>A measurement of the antibody reaction of a biological specimen to the HIV-1 virus.</def-definition>
HIV-1 Antibody Measurement
HIV Measurement
HIV-1 Antibody Measurement
HIV-1 Antibody Measurement
HIV-1 Antibody Measurement
The determination of the antibody reaction of a sample to the HIV-1 virus.
Clinical Data Interchange Standards Consortium Terminology
owl:Class
CDISC SEND Terminology
CDISC SDTM Terminology
HIV1AB
CL384778
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Name
owl:Class
<def-source>CDISC</def-source><def-definition>A measurement of the myelocytes per unit of a biological specimen.</def-definition>
C74662
Myelocyte Count
Myelocytes
Leukocyte Count
Myelocyte Count
MYCY
Clinical Data Interchange Standards Consortium Terminology
Myelocyte Count
Myelocyte Count
The determination of the number of myelocyte cells present in a sample.
CDISC SEND Terminology
C0455284
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Terminology
CDISC
Autopsy
A postmortem examination of the body that includes an examination of the internal organs and structures after dissection to determine the cause of death and the nature of pathological changes.
Autopsy
Anatomic Pathology Procedure
Laboratory Procedure
C25153
Autopsy
C0004398
Autopsy
owl:Class
Anti-Tumor Necrosis Factor Therapy
anti-TNF therapy
Therapeutic or Preventive Procedure
C15577
Anti-Tumor Necrosis Factor Therapy
owl:Class
Anti-Tumor Necrosis Factor Therapy
CL030735
anti-TNF-alpha therapy
Anti-Cytokine Therapy
Drug treatment to reduce the activity of tumor necrosis factor, particulary to control inflammation in disease modalities.
Anti-Tumor Necrosis Factor Therapy
Permutation
Permutation
Arrangement number
C64219
Statistical Test
A set of elements are rearranged or reindexed in various and different orders. In the rearrangement process, none of the elements are lost, added, or changed.
Qualitative Concept
Permutation
Order
owl:Class
CL369122
Permutation
Nutrition, Vitamins, Other
Nutrition, Vitamins
Role of vitamins other than A,B,C, or E, their precursons, and their analogs in cancer causation or prevention and in general health.
Research Activity
Nutrition, Vitamins, Other
Nutrition, Vitamins, Other
owl:Class
Nutrition, Vitamins, Other
CL102256
C15966
C0149783
Steroid Therapy
Endocrine Drug Therapy
Therapeutic or Preventive Procedure
C15370
Steroid Therapy
Steroid Therapy
<def-source>NCI-GLOSS</def-source><def-definition>Treatment with corticosteroid drugs to reduce swelling, pain, and other symptoms of inflammation.</def-definition>
steroid therapy
owl:Class
Steroid Therapy
The process of obtaining subjects for a study.
CL108471
Activity
Accrual
Accrual
Accrual
owl:Class
Action
C25403
Accrual
C0242793
Disease-Free Survival
<def-source>NCI-GLOSS</def-source><def-definition>Length of time after treatment during which no cancer is found. Can be reported for an individual patient or for a study population.</def-definition>
Disease-Free Survival
Disease-Free Survival
Survival
owl:Class
Disease-Free Survival
C17751
disease-free survival
Temporal Concept
Time Series Analysis
Time Series Analysis
owl:Class
Statistical Technique
C0681939
Time Series Analysis
There are two main goals of time series analysis: (a) identifying the nature of the phenomenon represented by the sequence of observations, and (b) forecasting (predicting future values of the time series variable).
Quantitative Concept
C18235
Time Series Analysis
Representation of data as a chronological sequence of events. Each event occurs at an instant in time and marks a change of state in a system.
Research Activity
Modeling
C75360
CL384481
owl:Class
Discrete Modeling
Discrete Modeling
Discrete Modeling
Discrete Modeling
owl:Class
Esophagectomy
Therapeutic or Preventive Procedure
Subtototal Esophagectomy
Procedure_Has_Partially_Excised_Anatomy only Esophagus
Subtototal Esophagectomy
Subtototal Esophagectomy
C51579
Surgical removal of part of the esophagus.
CL355519
Subtototal Esophagectomy
owl:Class
Hyperfractionated Radiation Therapy
Therapeutic or Preventive Procedure
Hyperfractionated Radiation Therapy
CL365610
Hyperfractionated Radiation Therapy
Hyperfractionated Radiation Therapy
Hypofractionated Radiotherapy
Radiation Therapy
C62725
Secondary Prevention
C15712
owl:Class
Therapeutic or Preventive Procedure
Secondary Prevention
Procedures or treatment processes designed to prevent complications (e.g., modifying a drug or surgical procedure to prevent complications).
Secondary Prevention
Preventive Intervention
Secondary Prevention
C0679699
Prevention, Secondary
Ovarian Papanicolaou Test
Papanicolaou Test
Ovarian Pap Test
Ovarian Papanicolaou Test
Ovarian Papanicolaou Test
C62671
owl:Class
Laboratory Procedure
Ovarian Papanicolaou Test
CL034835
Diagnostic Procedure
Gastrectomy
C0017118
Gastrectomy
<def-source>NCI-GLOSS</def-source><def-definition>(gas-TREK-toe-mee) An operation to remove all or part of the stomach.</def-definition>
Gastrectomy
owl:Class
Abdominal Surgical Procedure
Procedure_Has_Excised_Anatomy only Stomach
Therapeutic or Preventive Procedure
Surgical removal of part or all of the stomach.
Digestive System Surgery
gastrectomy
Gastrectomy
C15236
Bone Conduction Hearing Test
CL360580
Bone Conduction Assessment
Bone Conduction Assessment
Bone Conduction Assessment
Bone Conduction Assessment
Audiometric Test
Diagnostic Procedure
owl:Class
C60916
A test of the transmission of sound to the inner ear through the bones of the skull. This testing can measure functionality of the inner ear independent of the functionality of the outer and middle ears.
owl:Class
Radiology, Treatment Planning
Radiology, Treatment Planning
C15848
Clinical Service
Radiology, Treatment Planning
CL000824
Health Care Activity
Radiology, Treatment Planning
Discover
See for the first time; identify.
Discover
owl:Class
Discover
Activity
Action
C62262
Discover
Discovery
CL365206
The determination of the amount of interleukin 9 present in a sample.
C74837
Laboratory Procedure
Interleukin 9 Measurement
Interleukin 9 Measurement
INTLK9
Interleukin 9
Cytokine Measurement
CDISC SDTM Laboratory Test Terminology by Code
CL384319
owl:Class
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
Interleukin 9 Measurement
<def-definition>A measurement of the interleukin 9 in a biological specimen.</def-definition><def-source>CDISC</def-source>
Interleukin 9 Measurement
CDISC SDTM Terminology
owl:Class
New Diagnosis
Idea or Concept
New Diagnosis
C54731
Diagnosis
New Diagnosis
New Diagnosis
CL360140
C0205848
Death Rate
Quantitative Concept
owl:Class
Mortality Rate
Death Rate
Population-Based Statistic
Death Rate
Death Rate
C53346
owl:Class
C63336
Vaccine Therapy
CL365777
Non-Tumor Cell-Derived Vaccine Therapy
Non-Tumor Cell-Derived Vaccine Therapy
Therapeutic or Preventive Procedure
Non-Tumor Cell-Derived Vaccine Therapy
Non-Tumor Cell-Derived Vaccine Therapy
Waxy Cell Cast Measurement
Urine Sediment Analysis Measurement
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Terminology
CDISC
The determination of the number of waxy cell casts present in a urine sample.
<def-source>CDISC</def-source><def-definition>A measurement of the waxy casts present in a urine specimen.</def-definition>
CL384445
Waxy Cell Cast Measurement
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Name
Waxy Cell Cast Measurement
CSWAX
Clinical Data Interchange Standards Consortium Terminology
Waxy Casts
Waxy Cell Cast Measurement
C74777
Laboratory Procedure
owl:Class
Light Microscopy
Confocal Microscopy
Laboratory Procedure
C0242842
Confocal Microscopy
Confocal Microscopy
C17753
owl:Class
Confocal Microscopy
Confocal Laser Scanning Microscopy
A system of (usually) epifluorescence light microscopy in which a fine laser beam of light is scanned over the object through the objective lens. The technique is particularly good at rejecting light from outside the plane of focus and so produces higher effective resolution than is normally achieved.
Quantitative Reverse Transcriptase PCR
Quantitative Reverse Transcriptase PCR
Quantitative Reverse Transcriptase PCR
Laboratory Procedure
qRTPCR
C28408
Quantitative RTPCR
Molecular Biology Research Technique
Quantitative PCR: a method to measure very small amounts of RNA transcripts as cDNA targets. There are two strategies currently used, one is called Competitive RTPCR and the other is called Real-Time PCR.
owl:Class
Reverse Transcriptase-Polymerase Chain Reaction
Quantitative Reverse Transcriptase PCR
CL101866
Pemphigoid Antibody Measurement
The determination of the amount of pemphigoid antibodies present in a sample.
owl:Class
Pemphigoid Antibody Measurement
C81988
Immunology Test
Pemphigoid Antibody Measurement
Pemphigoid Antibody Measurement
Vaccine Related Non-Development, Total
CL002960
Vaccine Development
Vaccine Related Non-Development, Total
Health Care Activity
Vaccine Related Non-Development, Total
C15921
owl:Class
Vaccine Related Non-Development, Total
Clinical Data Interchange Standards Consortium Terminology
Epithelial Cell Count
C74775
Urine Sediment Analysis Measurement
CDISC SDTM Terminology
CL384429
CDISC
Tubular Epithelial Cell Count
owl:Class
CDISC SEND Terminology
Laboratory Procedure
Tubular Epithelial Cell Count
The determination of the number of tubular epithelial cells present in a urine sample.
CDISC SDTM Laboratory Test Terminology by Name
<def-source>CDISC</def-source><def-definition>A measurement of the tubular epithelial cells present in a urine specimen.</def-definition>
Tubular Epithelial Cell Count
Tubular Epithelial Cells
EPITUCE
Tubular Epithelial Cell Count
CDISC SDTM Laboratory Test Terminology by Code
C19340
Laboratory Procedure
Reflectance or Transmission Spectroscopy
CL003820
Reflectance or Transmission Spectroscopy
Spectroscopy
Reflectance or Transmission Spectroscopy
The spectroscopic analysis of light reflected from a polished sample. The peaks of reflectance/transmittance occur in the same spectral region where the sample absorbs light. In near infrared (IR) reflectance/transmission spectroscopy (NIRS), the reflectance signals result from bending and stretching vibrations in molecular bonds between carbon, nitrogen, hydrogen, and oxygen. (from FRTR Field Sampling and Analysis Technologies Reference Guide (online))
owl:Class
Reflectance or Transmission Spectroscopy
FEV6
Forced Expiratory Volume in 6 Seconds
Forced Expiratory Volume 6 Test
Pulmonary Function Test
Forced Expiratory Volume in 6 Seconds
Forced Expiratory Volume 6
C47843
A test of lung function, the FEV6 is the volume exhaled during six seconds of a forced expiratory maneuver started from the level of total lung capacity.
CL342086
Forced Expiratory Volume in 6 Seconds
owl:Class
Forced Expiratory Volume in 6 Seconds
Diagnostic Procedure
Mixed Category Laboratory Procedure
Biomarker Analysis
C64263
Laboratory Biomarker Analysis
Laboratory Biomarker Analysis
Laboratory Biomarker Analysis
Laboratory Biomarker Analysis
owl:Class
CL369097
Laboratory Procedure
Complement C3 Measurement
Complement Measurement
Complement C3 Measurement
Complement C3 Measurement
The determination of the amount of complement C3 present in a sample.
Laboratory Procedure
Complement C3 Measurement
owl:Class
C80174
A process used for separating mixtures by virtue of differences in absorbency. It involves stationary and mobile phases. The stationary phase was packed in a column with materials that can be of any partitioning capability, adsorption, ion exchange, or affinity. The mobile phase (either liquid or gas) is the mixture that required to be separated.
Column Chromatography
Column Chromatography
Chromatography
Column Chromatography
owl:Class
Column Chromatography
Laboratory Procedure
C0684296
C18242
Activity
Private Label Distribution
Private Label Distribution
FDA
Structured Product Labeling Business Operation Terminology
Private Label Distribution
CL383693
PRIVATE LABEL DISTRIBUTION
owl:Class
C73608
Private Label Distribution
Distribution
Consensus Clustering
Consensus Clustering
Cluster Analysis
Consensus Clustering
owl:Class
Consensus Clustering Analysis
A method to represent the consensus across multiple runs of a clustering algorithm, to determine the number of clusters in the data, and to assess the stability of the discovered clusters. The method can also be used to represent the consensus over multiple runs of a clustering algorithm with random restart (such as K-means, model-based Bayesian clustering, SOM, etc.), so as to account for its sensitivity to the initial conditions. It also provides for a visualization tool to inspect cluster number, membership, and boundaries.
Consensus Clustering
Research Activity
CL369077
C64199
Carry
Carrying
Carrying
owl:Class
C81005
Carrying
Carrying
The act of moving while supporting something in one's hands or on one's body.
Daily or Recreational Activity
Physical Activity
Non-Hematopoietic Stem Cell Research
CL024203
Biomedical Occupation or Discipline
Non-Hematopoietic Stem Cell Research
Non-Hematopoietic Stem Cell Research
owl:Class
Stem Cell Research
Non-Hematopoietic Stem Cell Research
C16202
Antibiotic Prophylaxis
owl:Class
Administration of antibiotics with the intent of preventing bacterial infection.
Antibiotic Prophylaxis
Frequently used in persons with heart disease, prosthetic heart valves, joints, etc.
C51993
Preventive Intervention
Therapeutic or Preventive Procedure
C0282638
Antibiotic Prophylaxis
Antibiotic Prophylaxis
Behavioral Research
Behavior Research, Direct
Behavior Research, Direct
CL000088
owl:Class
Behavior Research, Direct
C15770
Behavior Research, Direct
Research Activity
Research concerning people's behavior in the context of cancer, i.e., how people's behavior affects their chance of developing cancer.
Warburg Therapy
Therapeutic or Preventive Procedure
owl:Class
C0184633
Warburg Therapy
Oxygen Therapy
CAM Pharmacological or Biological Treatment
C29545
The cornerstone of oxygenation therapy is the presumption that human disease, including cancer, is caused by a deficit of tissue oxygen. According to proponents, hypoxia results in anaerobic fermentation, a loss of capacity for oxidative detoxification of toxins and metabolic products, and failure of immune killing of invading bacteria and viruses. To restore ability to carry out these functions, oxygenation promoters propose using chemicals they claim will release oxygen in tissue or act as germicides in vivo.
Warburg Therapy
Warburg Therapy
C74809
Clinical Data Interchange Standards Consortium Terminology
Interleukin 13 Measurement
Interleukin 13
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Code
<def-definition>A measurement of the interleukin 13 in a biological specimen.</def-definition><def-source>CDISC</def-source>
Interleukin 13 Measurement
Cytokine Measurement
Interleukin 13 Measurement
Laboratory Procedure
CL384290
CDISC SDTM Laboratory Test Terminology by Name
INTLK13
Interleukin 13 Measurement
CDISC SDTM Terminology
owl:Class
The determination of the amount of interleukin 13 present in a sample.
Vaccine Development, Other Non-AIDS
Vaccine Development
Vaccine Development, Other Non-AIDS
CL001069
Vaccine Development, Other Non-AIDS
owl:Class
Health Care Activity
C15867
Vaccine Development, Other Non-AIDS
C81987
Islet Neogenesis Associated Protein Antibody Measurement
Islet Neogenesis Associated Protein Antibody Measurement
Islet Neogenesis Associated Protein Antibody Measurement
Immunology Test
The determination of the amount of islet neogenesis associated protein antibody present in a sample.
Islet Neogenesis Associated Protein Antibody Measurement
owl:Class
Diagnostic Procedure
Diagnostic Mammography
Mammography
Diagnostic Mammography
owl:Class
C79416
Diagnostic Mammography
Diagnostic Mammography
Interleukin 7 Measurement
<def-definition>A measurement of the interleukin 7 in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Laboratory Test Terminology by Code
CDISC SEND Terminology
Interleukin 7 Measurement
CDISC SDTM Laboratory Test Terminology by Name
owl:Class
Laboratory Procedure
Interleukin 7 Measurement
Cytokine Measurement
CDISC SDTM Terminology
CL384317
Interleukin 7
Interleukin 7 Measurement
C74835
INTLK7
Clinical Data Interchange Standards Consortium Terminology
The determination of the amount of interleukin 7 present in a sample.
DOSFRQ
Treatment Regimen
Dose-Rate
dose-rate
CDISC Observation Class Terminology
<def-source>NCI-GLOSS</def-source><def-definition>The strength of a treatment given over a period of time.</def-definition>
C15682
Dose-Rate
Dose-Rate
Dose-Rate
Quantitative Concept
CL031819
owl:Class
Health Education
Health Promotion and Care
Health Promotion and Care
Educational Activity
Health Promotion and Care
CL000448
Health Promotion and Care
Promotion of the use of available health care resources and the adoption of more healthful lifestyles, and attempts to make resources available to underserved populations and to make these populations aware of the resource availability.
C18830
owl:Class
Research Activity
Epidemiology Research
C15721
Epidemiology Research
Epidemiologic Trial
C0699910
Epidemiology Research
Epidemiologic Study
owl:Class
Epidemiology Research
The study of human populations to identify causes of disease and factors determining and influencing the frequency and distribution of disease, injury, and other health related events.
Research Activity
Epidemiological Study
Epidemiologic Research
Chromosomal Translocation Analysis
Laboratory Procedure
owl:Class
Chromosomal Translocation Analysis
Chromosomal Translocation Analysis
Chromosomal Translocation Analysis
C63326
Cytogenetic Analysis
CL365540
Request
Requested
Request
Conceptual Entity
Request
C48312
Express the need or desire for; ask for.
Request
Action
owl:Class
C1272683
Merge
Merge
Merge
C64266
Merged
owl:Class
Activity
Action
Merge
CL369103
To join, combine, or mix together.
Gel Electrophoresis
An electrophoresis procedure, in which a sample is introduced into a capillary tube and the components are separated by the application of high voltage. Due to the large surface to volume ratio, cooling is more efficient, allowing use of higher voltages. As a result, separation occurs more quickly and sensitivity is increased. The technique allows for separation of proteins, nucleic acids, and carbohydrates.
Capillary Electrophoresis
Fractionation, Capillary Electrophoresis
C17637
Capillary Electrophoresis
Capillary Electrophoresis
owl:Class
C0201699
Capillary Electrophoresis
Laboratory Procedure
Molecular Biology Research Technique
Preservation
Preservation
The activity of protecting something from loss or danger; a process that saves organic substances from decay; to maintain or keep intact.
owl:Class
Activity
Preserved
Preservation
C52243
C0456735
Action
Preservation
Genetic Technique
Chromosomal, biochemical, intracellular, and other methods used in the study of genetics, including RNA and DNA chemistry.
Genetic Technique
Genetic Technique
Genetic Technique
Molecular Biology Research Technique
Molecular Genetic Technique
owl:Class
C0017395
C16623
C18190
Histopathologic Examination
Histopathologic Examination
Medical Examination
Histopathologic Examination
The microscopic study of characteristic tissue abnormalities by employing various cytochemical and immunocytochemical stains.
Histopathologic Study
Histopathologic Examination
Diagnostic Procedure
owl:Class
C0498031
Histopathologic
Histopathology
owl:Class
Bioconductor caAffy Contrasts Normalization
Bioconductor caAffy Contrasts Normalization
Statistical Technique
Bioconductor caAffy Contrasts Normalization
Bioconductor caAffy Contrasts Normalization
A method to normalize intensities using the contrasts method, as defined in documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html
Activity
CL369464
C63931
Yeast One/Two-Hybrid System
<def-source>CSP2000</def-source><def-definition>two hybrid proteins interact to transcriptionally activate a reporter gene in vivo.</def-definition>
Yeast One Hybrid System
Expression Technologies for DNA and RNA
Yeast One/Two-Hybrid System
Yeast One/Two-Hybrid System
Molecular Biology Research Technique
C1961118
Molecular biology technique used to identify interacting proteins in a yeast model. A protein of interest (the bait) is fused to the DNA-binding domain of a yeast transcription factor (usually GAL4). (Usually) a cDNA library is fused to the GAL4 activation domain. The library is then introduced into yeast cells carrying the bait construct. Functional interaction of the bait with fusion proteins from the library bring together the binding and activation domains of the transcription factor, allowing activation of a reporter gene. (syn: yeast two-hybrid system) (NCI/OSP)
C18140
Yeast Two Hybrid System
owl:Class
Two Hybrid
Yeast One/Two-Hybrid System
owl:Class
Electroanalgesia
Piezo-Electric Current Therapy
PECT
Piezo-Electric Current Therapy
Piezo-Electric Current Therapy
Therapeutic or Preventive Procedure
CL100602
C21031
A minimally invasive, experimental form of electroanalgesia based upon the theory that rapid electrical stimulation of A-delta and C pain fibers can lead to nociceptive afferent input depression. This may be due to exogenous endorphin production release after stimulation. (White, Li, and Chiu)
Piezo-Electric Current Therapy
The detection by physical, chemical, or biological means of an altered DNA sequence. Includes SSCP, DNA sequencing, hybridization, and reporter gene expression.
owl:Class
Mutation Detection
Molecular Analysis
Laboratory Procedure
Mutation Detection
Mutation Detection
C18890
CL000567
Diagnostic Procedure
Mutation Detection
Clinical Data Interchange Standards Consortium Terminology
CDISC
CL356591
t-test
owl:Class
Parametric Test
Quantitative Concept
C53231
t-Test
Clinical Data Interchange Standards Consortium Glossary Terminology
A statistical hypothesis test based on a test statistic whose sampling distribution is a t-distribution. The term "t-test" is often used in a narrower sense: it refers to a popular test aimed at testing the hypothesis that the population mean is equal to some value m (see also t-statistic). The most popular t-tests are aimed at testing the following hypotheses: 1. The population mean is as hypothesized (the population variance is not known); 2. The means of two populations are equal (the population variances are not known but equal); 3. The means of two populations are equal (the population variances are not known and not equal); 4. The correlation coefficient for two random variables is zero; 5. The slope of the population regression line is zero.
t-Test
<def-source>CDISC</def-source><def-definition>A statistical test used to compare the means of two groups of test data.</def-definition>
t-Test
t-Test
Physical Activity
Physical Activity
Any form of exercise or movement. Physical activity may include planned activity such as walking, running, basketball, or other sports. Physical activity may also include other daily activities such as household chores, yard work, walking the dog, etc.
Daily or Recreational Activity
C0026606
Physical Activity
C17708
owl:Class
Activity
Physical Activity
Art Therapy
A therapeutic technique in which art is used to express and explore emotions and to help address or heal emotional problems or traumas.
Art Therapy
Art Therapy
Mental Process
Art Therapy
owl:Class
C0003827
Mind-Body Intervention Procedure
C67031
Cross-Correlation
Cross-Correlation
Cross-Correlation
CL374303
Statistical Technique
A statistical measure timing the movements and proximity of alignment between two different information sets of a series of information. A function of the relative time between the signals, it is a measure of similarity of two signals, commonly used to find features in an unknown signal by comparing it to a known one.
Research Activity
Cross-Correlation
owl:Class
C68833
Cross Correlation
Immunology Test
Hepatitis B Virus Surface Antigen Measurement
CDISC SDTM Laboratory Test Terminology by Code
Hepatitis B Virus Surface Antigen Measurement
C64850
Hepatitis B Virus Surface Antigen Measurement
CDISC SEND Terminology
Hepatitis B Virus Surface Antigen
Laboratory Procedure
CDISC SDTM Terminology
CDISC
owl:Class
Hepatitis B Virus Surface Antigen Measurement
C0201477
<def-source>CDISC</def-source><def-definition>A measurement of the surface antigen reaction of a biological specimen to the Hepatitis B virus.</def-definition>
HBSAG
A deteremination of the presence of hepatitis B virus surface antigen.
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Name
<def-source>NCI-GLOSS</def-source><def-definition>(aw-TAHL-o-gus) A procedure in which bone marrow is removed from a person, stored, and then given back to the person after intensive treatment.</def-definition>
Autologous Bone Marrow Transplantation
autologous bone marrow transplantation
Bone Marrow Transplantation
Therapeutic or Preventive Procedure
ABMT
Autologous Bone Marrow Transplantation
Autologous Marrow Transplantation
C15395
Bone marrow transfer in which the patient is his own donor. Bone marrow is removed prior to bone marrow ablation treatment and then returned to reconstitute the hematopoietic system. Prior to reinfusion the bone marrow is often treated to purge it of residual tumor cells.
owl:Class
Autologous Bone Marrow Transplantation
C0194037
Autologous Bone Marrow Transplantation
Autologous Bone Marrow Transplant
Quantitative Concept
Non-Parametric Test
Chi-square test is a statistical test for testing the null hypothesis that the distribution of a discrete random variable coincides with a given distribution. It is one of the most popular goodness-of-fit tests.
C0008041
C53235
Chi-Square Test
Chi-Square Test
Chi-Square Test
Chi-Square Test
owl:Class
Biopsy of Tongue
Biopsy of Tongue
Lingual Biopsy
C51930
Removal of tissue from the tongue for microscopic examination.
owl:Class
Biopsy of Tongue
Procedure_Has_Partially_Excised_Anatomy only Tongue
Diagnostic Procedure
Biopsy of Tongue
CL354451
Biopsy
Nurses' Health Study
Research Activity
C16105
The Nurses' Health Study was begun in 1976 with the establishment of a cohort of 120,700 women aged 30-55 and was principally designed to assess risk factors for breast cancer. Cohort members initially resided in 11 geographically dispersed states representing the Northeast (Massachusetts, Connecticut, New York, New Jersey, Pennsylvania, Maryland), Northcentral (Ohio, Michigan), the West (California) and the South (Texas, Florida); although the majority of participants still reside in the original 11 states, members of the cohort currently live in all 50 states. These women report on exposures and disease outcomes every two years and follow-up in the cohort has been maintained at a level of better than 90% through 1990.
CL008761
Epidemiology Research
Nurses' Health Study
owl:Class
Nurses' Health Study
Nurses' Health Study
owl:Class
CL322355
Average
Average
C37917
Average
A statistical calculation describing the central tendency of a set of numbers; used to interpret quantitative data.
Statistical Technique
Average
Quantitative Concept
CL384775
The determination of the amount of free testosterone present in a sample.
CDISC SEND Terminology
owl:Class
Clinical Data Interchange Standards Consortium Terminology
C74785
Free Testosterone Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the free testosterone in a biological specimen.</def-definition>
Testosterone, Free
Free Testosterone Measurement
Hormone Measurement
Laboratory Procedure
CDISC
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Terminology
TESTOSFR
Free Testosterone Measurement
CDISC SDTM Laboratory Test Terminology by Name
Free Testosterone Measurement
An act of alteration involving reconsideration and modification.
C54087
Revised
Revision
Revision
owl:Class
Revise
Revision
Activity
C0439617
Revision
Action
Detection of Minimal Residual Disease
owl:Class
CL000289
C15795
Detection
The discovery of a tumor or cancer after primary, potentially curative therapy.
Detection of Minimal Residual Disease
Detection of Minimal Residual Disease
Detection of Minimal Residual Disease
Diagnostic Procedure
Clinical Data Interchange Standards Consortium Terminology
Open Label Study
CDISC SDTM Trial Blinding Schema Terminology
Clinical Data Interchange Standards Consortium Glossary Terminology
Open Label Study
owl:Class
OPEN LABEL
Open Label Study
Research Activity
CDISC SDTM Terminology
A type of study that stipulates both the health provider and the subject be aware of the drug or treatment assignment.
C49659
Open Label Study
<def-source>CDISC</def-source><def-definition>A trial in which subjects and investigators know which product each subject is receiving; opposite of a blinded or double-blind study. (CDISC glossary)</def-definition>
Trial Blinding Schema
CDISC
CL355308
Action
C25538
CL052289
Intake
owl:Class
Intake
Conceptual Entity
Intake
The process of taking in a substance, especially by eating or drinking, or the quantities thereof; admittance of people to a place or organization at a particular time.
Intake
owl:Class
electrodesiccation
Electrodesiccation
C15391
Electrodesiccation
C0185056
Electrodesiccation
Therapeutic or Preventive Procedure
Electrodesiccation
<def-source>NCI-GLOSS</def-source><def-definition>(e-LEK-tro-des-ih-KAY-shun) The drying of tissue by a high-frequency electric current applied with a needle-shaped electrode.</def-definition>
Fulguration
Local Therapy
owl:Class
Research Activity
CL014991
The overall goal is to understand the causes of health disparities in cancer and to develop effective interventions to eliminate these disparities. (from The NCI Strategic Plan to Reduce Health Disparities)
Cancer Research
NCI Strategic Plan to Reduce Health Disparities
NCI Strategic Plan to Reduce Health Disparities
NCI Strategic Plan to Reduce Health Disparities
NCI Strategic Plan to Reduce Health Disparities
Intellectual Product
C16177
Fluctuate
Fluctuate
Activity
To be unstable, having ups and downs.
Fluctuating
Action
Fluctuate
C67528
owl:Class
Fluctuation
Fluctuate
C0231241
Cordotomy
Pain Management Method
Therapeutic or Preventive Procedure
Neurosurgical Procedure
Cordotomy
C21001
Spinal cord section of lateral pathways to relieve pain. This procedure may be done open or percutaneous. (from Taber's)
Cordotomy
C0010009
owl:Class
Cordotomy
C0023087
Therapeutic or Preventive Procedure
owl:Class
A type of operation using the cutting powers of laser beams from various sources. The use of a laser either to vaporize surface lesions or to make bloodless cuts in tissue.
Conventional Laser Therapy
Laser Surgery
Therapeutic Surgical Procedure
Clinical, Surgery, Laser
Laser Therapy
Laser Surgery
Laser Surgery
Surgical Procedure by Method
Laser Surgery
C15268
Breast Feeding
The nursing of an infant at the mother's breast.
C25596
Nursing
Therapeutic or Preventive Procedure
Newborn Screening
Breast Feeding
Breast Feeding
Breast Feeding
owl:Class
Infant Nutrition
C0006147
CDISC SDTM Laboratory Test Terminology by Code
owl:Class
Acetylcholine Measurement
ACH
Acetylcholine Measurement
<def-definition>A measurement of the acetylcholine hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
Hormone Measurement
Acetylcholine
C74838
CDISC SDTM Terminology
CDISC SEND Terminology
C0523441
CDISC SDTM Laboratory Test Terminology by Name
Acetylcholine Measurement
The determination of the amount of acetylcholine hormone present in a sample.
Acetylcholine Measurement
Clinical Data Interchange Standards Consortium Terminology
Laboratory Procedure
Therapeutic Nutritional Supplementation
owl:Class
Therapeutic or Preventive Procedure
Nutritional Supplementation
C64893
Therapeutic Nutritional Supplementation
Nutritional Therapy
Therapeutic Nutritional Supplementation
CL370559
Therapeutic Nutritional Supplementation
Northern Blotting
C16355
C1621557
RNA Analysis
Laboratory Procedure
Blotting, Northern
Northern Blotting
Northern Blotting
owl:Class
Northern Blot
Northern Blotting
<def-source>MSH2001</def-source><def-definition>Detection of RNA that has been electrophoretically separated and immobilized by blotting on nitrocellulose or other type of paper or nylon membrane.</def-definition>
A common molecular biology procedure for detection of RNA molecules. RNA extracted from a sample was denatured and separated by slab gel electrophoresis, then blotted on to a nitrocellulose or nylon sheet and hybridized with labeled DNA or RNA that is complementary to the desired RNA, whose presence is subsequently indicated by autoradiography or other visualization techniques.
Research Activity
Study of Disease Management
The Study of Disease Management is one that involves evaluations of developing treatments, modalities or preventive measures and has outcomes with direct clinical relevance. Most clinical trials fit within this category.
owl:Class
Study of Disease Management
C39520
Study of Disease Management
CL323616
Research Activity
Study of Disease Management
Redirected Cytotoxicity
Redirected Cytolysis
Redirected Cytolysis
The killing of target cells by changing the natural specificity of cytotoxic T cells by the use of an antibody or other molecule capable of binding to both the T cell and to the target cell. Often involves hybrid (bispecific) antibodies having distinct specificities for the T cell and for the target cell. (NCI/OSP)
CL000835
C15851
Therapeutic or Preventive Procedure
Immunotherapy
Cell Function
owl:Class
Redirected Cytolysis
Redirected Cytolysis
Type II Collagen N-Telopeptide Measurement
owl:Class
Protein or Enzyme Type Measurement
The determination of the amount of the type II collagen N-telopeptide present in a sample.
Type II Collagen N-Telopeptide Measurement
Type II Collagen N-Telopeptide Measurement
C82041
Type II Collagen N-Telopeptide Measurement
Functional Concept
Registration
owl:Class
Registration
Registration
The act of listing or recording officially; officially qualified or enrolled.
Registered
Registration
Registering
C25646
Action
Activity
CL052614
Complement Measurement
The determination of the amount of complement present in a sample.
Complement Measurement
Complement Measurement
C80160
owl:Class
Complement Measurement
Immunology Test
Laboratory Procedure
C1265875
Decay
Action
A gradual deterioration or decline to an inferior state.
Decay
owl:Class
C75947
Phenomenon or Process
Decay
Decay
C25404
owl:Class
A thing done.
Activity
Action
CL370613
Action
Generic Action
Action
Activity
Action
Departure
Activity
Departed
Depart
Departure
C53464
CL357914
Action
The act of leaving a destination.
owl:Class
Departure
Departure
ALPCREAT
CDISC SEND Terminology
Alkaline Phosphatase to Creatinine Ratio Measurement
Alkaline Phosphatase to Creatinine Ratio Measurement
Laboratory Procedure
Alkaline Phosphatase to Creatinine Ratio Measurement
owl:Class
Alkaline Phosphatase to Creatinine Ratio Measurement
Alkaline Phosphatase/Creatinine
The determination of the ratio of alkaline phosphatase compared to creatinine present in a sample. The measurement may be expressed as a ratio or percentage.
<def-definition>A relative measurement (ratio or percentage) of the alkaline phosphatase to creatinine in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
C79438
Clinical Data Interchange Standards Consortium Terminology
Urine Protein Measurement
C15822
Nutrition Research, Applied Non-Clinical Trials
Nutrition Research, Applied Non-Clinical Trials
Nutrition Research, Applied Non-Clinical Trials
CL000601
Research Activity
Nutrition Research, Applied Non-Clinical Trials
owl:Class
Applied Research
Primary Cell Culture
The cells taken from a tissue source, and their progeny, grown in culture before subdivision and transfer to a sub culture.
CL003677
Cell Culture
C19315
Primary Cell Culture
Primary Cell Culture
Laboratory Procedure
Culturing, in vitro Vertebrate, Primary
Primary Cell Culture
owl:Class
Indicates the progesterone receptor level measured in a primary tumor or in metastases. (>=10 is positive if measured in fmols/mg cytosol protein; Otherwise use institutional standards)
Clinical Attribute
PgR Status
C16149
Progesterone Receptor Status
Clinical Trial Eligibility Criteria
Progesterone Receptor Status
owl:Class
CL014331
Progesterone Receptor Status
Progesterone Receptor Status
Thermal Ablation Therapy
Thermal Ablation Therapy
Ablation Therapy
thermal ablation
Hyperthermia Treatment
owl:Class
CL035135
Thermal Ablation Therapy
Therapeutic or Preventive Procedure
Thermal Ablation Therapy
<def-source>NCI-GLOSS</def-source><def-definition>A procedure using heat to remove tissue or a part of the body, or destroy its function. For example, to remove the lining of the uterus, a catheter is inserted through the cervix into the uterus, a balloon at the end of the catheter is inflated, and fluid inside the balloon is heated to destroy the lining of the uterus.</def-definition>
C15670
Menopausal Status
CL014333
Clinical Trial Eligibility Criteria
Clinical Attribute
owl:Class
C16151
Menopausal Status
Menopausal Status
Menopausal Status
owl:Class
Modeling of Functional Interactions
Computer Modeling
Modeling of Functional Interactions
CL000552
Modeling of Functional Interactions
Research Activity
C18880
Modeling of Functional Interactions
Using mathematical methods to simulate processes to predict the interaction of proteins at the functional level.
Subtract MM Probe Correction Method
C64233
Subtract MM Probe Correction Method
owl:Class
Subtract MM Probe Correction Method
Correct perfect match (PM) probe levels by subtracting mismatch (MM) probe levels. Defined in the documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html.
CL369364
Subtract MM Probe Correction Method
Probe Correction Method
Activity
Quantitative Concept
Statistical Technique
CNAT Probe Normalization Method
CNAT Probe Normalization Method
Probe Normalization Method
A method for performing probe-level normalization of signal intensity to generate summaries file using CNAT method.
CNAT Probe Normalization Method
CNAT Probe Normalization Method
owl:Class
C81021
Antioxidants Therapy
CL371397
Therapeutic or Preventive Procedure
Antioxidants Therapy
Treatment with antioxidants in order to protect cells against damage caused by oxygen-free radicals.
C67025
Biologically Based Practices
Antioxidants Therapy
Antioxidants Therapy
owl:Class
Therapeutic Surgical Procedure
Surgical Wound Closure
Surgical Wound Closure
CL365827
owl:Class
Surgical Wound Closure
Therapeutic or Preventive Procedure
C63340
Surgical Wound Closure
owl:Class
Aspartate Aminotransferase Antigen Measurement
Aspartate Aminotransferase Antigen Measurement
C81978
Aspartate Aminotransferase Antigen Measurement
Immunology Test
Aspartate Aminotransferase Antigen Measurement
The determination of the amount of aspartate aminotransferase antigen present in a sample.
CL100466
C20680
Electrolaryngeal Speech
Alaryngeal Speech
Electrolaryngeal Speech
owl:Class
Individual Behavior
Electrolaryngeal Speech
Electrolaryngeal Speech
Artificial Laryngeal Speech
Intrahepatic Infusion
intrahepatic infusion
Intrahepatic Infusion Procedure
C15731
Intrahepatic Infusion Procedure
Administration of a fluid form of the drug via a blood vessel into the liver over the sustained period of time.
Hepatic Arterial Infusion
Therapeutic or Preventive Procedure
CL032077
IHI
owl:Class
Intrahepatic Infusion Procedure
Infusion Procedure
Intrahepatic Infusion Procedure
CL015989
Whole-Brain Radiotherapy
Whole-Brain Radiotherapy
C16187
Extensive Radiation
Prior Extensive Radiation
Whole-Brain Radiotherapy
Clinical Attribute
Whole-Brain Radiotherapy
owl:Class
Radiation treatment modality used as major component in treatment of primary and metastatic brain tumors. This is a standard treatment for multiple brain metastases.
Neurosurgical Procedure
Craniotomy
owl:Class
Craniotomy
Head and Neck Surgery
Craniotomy
incision of the skull
Surgical creation of an opening of the skull.
C0010280
Procedure_Has_Target_Anatomy only Skull
C15214
<def-source>NCI-GLOSS</def-source><def-definition>(kray-nee-AH-toe-mee) An operation in which an opening is made in the skull.</def-definition>
Therapeutic or Preventive Procedure
Craniotomy
craniotomy
Consultation
Consultation
Consult
Occupational Activity
Action
C41188
Consultation
C0009818
Instruction Imperative
A conference between two or more people to consider a particular question; the act of deliberating together; confering with another researcher, physician, or expert about an issue or a case.
Consultation
owl:Class
Sezary Cell to Lymphocyte Ratio Measurement
Clinical Data Interchange Standards Consortium Terminology
C74655
CDISC
Blood Cell Count Ratio Measurement
CDISC SDTM Terminology
<def-source>CDISC</def-source><def-definition>A relative measurement (ratio or percentage) of Sezary cells (atypical lymphocytes with cerebriform nuclei) to all lymphocytes in a biological specimen.</def-definition>
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
SEZCELY
Sezary Cell to Lymphocyte Ratio Measurement
CL384347
Sezary Cells/Lymphocytes
Sezary Cell to Lymphocyte Ratio Measurement
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Code
owl:Class
The determination of the ratio of Sezary cells compared to all lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
Sezary Cell to Lymphocyte Ratio Measurement
Laboratory Biomarker Analysis
Diagnostic Laboratory Biomarker Analysis
Diagnostic Laboratory Biomarker Analysis
Diagnostic Procedure
C64900
CL370143
owl:Class
Diagnostic Laboratory Biomarker Analysis
Diagnostic Procedure
Diagnostic Laboratory Biomarker Analysis
Chemotherapy
Chemotherapy
Therapeutic or Preventive Procedure
Chemo
<def-source>NCI-GLOSS</def-source><def-definition>(kee-mo-THER-a-pee) Treatment with anticancer drugs.</def-definition>
Chemotherapy
Chemotherapy
Therapeutic Procedure
chemotherapy
owl:Class
C15632
Chemotherapy, Cancer, General
The use of synthetic or naturally-occurring chemicals for the treatment of diseases. Although this term is used to describe any therapy involving the use of chemical-based agents, it is particularly used to refer to the use of chemical-based agents to treat cancer. Antineoplastic chemotherapy works by arresting or killing the growth and spread of cancer cells. Chemotherapy may also include agents that enhance immune function or alter hormonal activity.
C0392920
Unnecessary Surgical Procedure
Unnecessary Surgical Procedure
Therapeutic or Preventive Procedure
Unnecessary Surgical Procedure
owl:Class
Surgical Procedure
C50833
Unnecessary Surgical Procedure
CL354311
C0195324
cone biopsy
Conization
conization
Diagnostic Procedure
Therapeutic or Preventive Procedure
Surgical removal of a cone-shaped portion of tissue from the uterine cervix.
Conization of Cervix
<def-source>NCI-GLOSS</def-source><def-definition>(ko-nih-ZAY-shun) Surgery to remove a cone-shaped piece of tissue from the cervix and cervical canal. Conization may be used to diagnose or treat a cervical condition.</def-definition>
Conization of Uterine Cervix
Cone Biopsy of Cervix
owl:Class
Procedure_Has_Partially_Excised_Anatomy only 'Cervix Uteri'
Conization
C15402
Conization
Conization
Gynecological Surgical Procedure
Research Activity
DICOM Study
owl:Class
DICOM Study
DICOM Study
Study
C63537
Study
One or more series of images taken on a single visit to a medical facility.
CL366337
<def-source>DICOM</def-source><def-definition>A collection of one or more series of Composite Instances (such as Images, Presentation States, or SR documents) that are logically related for the purpose of diagnosing a patient, created by one or more modalities or devices.</def-definition>
DICOM Study
Research Activity
owl:Class
Role of food additives in cancer causation or prevention and in general health.
Nutrition, Food Additives
C15235
Nutrition, Food Additives
Nutrition, Food Additives
Nutrition, Food Additives
C0016453
Nutrition, Dietary Components
Arthroplasty
Therapeutic or Preventive Procedure
Arthroplasty of the Knee
Procedure_Has_Target_Anatomy only 'Knee Joint'
Arthroplasty of the Knee
C51563
Surgical reconstruction or replacement of all or part of a damaged knee joint with an artificial joint or artificial components.
C0086511
Arthroplasty of the Knee
Arthroplasty of the Knee
owl:Class
CL003588
owl:Class
Cellular Assay
Cellular Assay
Research Activity
In vitro experiments conducted with intact, living cells.
in vitro Assay
Cellular Assay
Cellular Assay
C15959
OD260
Molecular Genetic Technique
CL342937
owl:Class
Absorbance at 260nm
A260
Absorbance at 260nm
Activity
Absorbance at 260nm
Absorbance at 260nm
The quantity of 260nm light that is not transmitted through a substance or solution.
In nucleic acid chemistry, this measure is proportional to the concentration of nucleic acid in solution.
C48169
Mucous Thread Measurement
CDISC SDTM Laboratory Test Terminology by Name
The determination of the number of mucous threads present in a sample.
MUCTHR
Chemistry Test
C74721
CDISC SDTM Laboratory Test Terminology by Code
Mucous Thread Measurement
CDISC SDTM Terminology
CL384418
Mucous Thread Measurement
Mucous Thread Measurement
CDISC SEND Terminology
Clinical Data Interchange Standards Consortium Terminology
CDISC
Laboratory Procedure
Mucous Threads
owl:Class
<def-source>CDISC</def-source><def-definition>A measurement of the mucous threads present in a biological specimen.</def-definition>
Indirect Pulp Cap
Indirect Pulp Cap
A procedure in which the nearly exposed pulp is covered with a protective dressing to protect the pulp from additional injury and to promote healing and repair via formation of secondary dentin.
Indirect Pulp Capping
CL356469
owl:Class
Indirect Pulp Cap
Indirect Capping
Indirect Pulp Cap
C52576
Therapeutic or Preventive Procedure
Dental Pulp Capping
HLA Matching
A process in which blood or tissue samples are analyzed to determine their human leukocyte antigen (HLA) profiles so that transplant materials can be transfered into a patient with the same or similar profile.
HLA Compatibility Testing
HLA Matching
owl:Class
HLA Matching
Laboratory Procedure
CL374454
Human Leukocyte Antigen Matching
HLA Matching
Immunology Test
C68707
C20065
Microdeposition
Thin layer deposition. Commonly used in integrated circuit fabrication.
Microdeposition
Microtechnique
CL015636
Laboratory Procedure
Microdeposition
owl:Class
Microdeposition
owl:Class
C1293994
A histological procedure, which is used for localization of RNA and DNA. Methyl green is a cation, which binds rather specifically to DNA and thus serves as a convenient means of staining nuclei in both fixed material and living cells. Pyronin, a red dye, is fairly specific for RNA with some binding to protein.
Laboratory Procedure
Methyl Green Pyronine Staining Method
Methyl Green Pyronine Staining Method
Methyl Green Pyronine Staining Method
Special Histology Staining Method
Methyl Green Pyronine Staining Method
MGP
C23017
Methyl Green Pyronine
Methyl Green Pyronine Staining Method
Non-Specific Immune-Modulator Therapy
owl:Class
CL029160
Non-Specific Immune-Modulator Therapy
Therapeutic or Preventive Procedure
Non-Specific Immune-Modulator Therapy
Non-Specific Immune-Modulator Therapy
C15461
Immunotherapy
Activity
C67005
Substitution Permitted
Substitution Permitted
CL371561
Substitution Permitted
Instruction Imperative
owl:Class
Substitution Permitted
Coagulation Study
C62656
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Name
PT
Clinical Data Interchange Standards Consortium Terminology
CDISC
Prothrombin Time Test
Prothrombin Time
<def-source>CDISC</def-source><def-definition>A blood clotting measurement that evaluates the extrinsic pathway of coagulation and is expressed in units of time or percent activity.</def-definition>
Prothrombin Time
Prothrombin Time
owl:Class
Prothrombin Time
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
C0033707
CDISC SEND Terminology
A measurement of the clotting time of plasma recalcified in the presence of excess tissue thromboplastin; it is a measure of the extrinsic pathway of coagulation. It is used to determine the clotting tendency of blood, in the measure of warfarin dosage, liver damage and vitamin K status. Factors measured are fibrinogen, prothrombin, and factors V, VII, and X.
C82013
Fibrin Degradation Products Measurement
Fibrin Degradation Products Measurement
Protein or Enzyme Type Measurement
Fibrin Degradation Products Measurement
owl:Class
Fibrin Degradation Products Measurement
The determination of the amount of fibrin degradation products present in a sample.
C0949353
Massage Therapy
Therapeutic or Preventive Procedure
Rolfing
Rolfing
owl:Class
Rolfing
C21125
A therapy designed to realign the body with gravity through fascial manipulation. (Taber's)
Rolfing
Laser Scanning Cytometry
owl:Class
Laser Scanning Cytometry
Laser Scanning Cytometry
C64861
Laser Scanning Cytometry
Laboratory Procedure
C1449707
Flow Cytometry
Repository Operation, Serum
Laboratory Procedure
Culturing, in vitro Repository Operations, Serum
CL000848
Repository Operation, Serum
C15853
Repository Operation, Serum
owl:Class
Repository Operation
Repository Operation, Serum
owl:Class
Human Subject Research
A study that has gone beyond the laboratory research and the testing that can be done with experimental animals, and needs to involve humans if it is to be continued at all. Under current law, usually the testing of a new pharmaceutical product or medical device on humans is mandatory. The concept also refers to population-based research in which an investigator directly interacts with individuals.
C41385
Research Activity
Human Subject Research
Research Activity
Human Subject Research
CL331984
Human Subject Research
CL365559
Dynamic Contrast-Enhanced Magnetic Resonance Imaging
DCE MRI
Dynamic Contrast-Enhanced Magnetic Resonance Imaging
DCE-MRI
Contrast-enhanced Magnetic Resonance Imaging
owl:Class
Dynamic Contrast-Enhanced Magnetic Resonance Imaging
Diagnostic Procedure
A modification of contrast-enhanced MRI that allows observation of functional properties in addition to structural properties.
C62665
Dynamic Contrast-Enhanced Magnetic Resonance Imaging
Extraordinary Opportunity: Research on Tobacco and Tobacco Related Cancers
Research Activity
C16139
CL014099
Goal : to expand our understanding of tobacco addiction and the biological mechanisms underlying tobacco-induced cancers, develop ways to keep people of all ages from using tobacco, create interventions to prevent tobacco-related cancers in smokers and former smokers, and develop treatments for tobacco addiction and the cancers it causes. (from NCI Initiatives Web page)
Extraordinary Opportunity: Research on Tobacco and Tobacco Related Cancers
Extraordinary Opportunities for Investment
Extraordinary Opportunity: Research on Tobacco and Tobacco Related Cancers
Extraordinary Opportunity: Research on Tobacco and Tobacco Related Cancers
owl:Class
The determination of the amount of transferrin present in a sample.
Transferrin Measurement
C82037
Protein or Enzyme Type Measurement
Transferrin Measurement
owl:Class
Transferrin Measurement
Transferrin Measurement
CDISC
The determination of the amount of apolipoprotein B present in a sample.
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
Apolipoprotein B
<def-source>CDISC</def-source><def-definition>A measurement of the apolipoprotein B in the low density lipoproteins of a biological specimen.</def-definition>
Apolipoprotein B Measurement
Apolipoprotein B Measurement
Clinical Data Interchange Standards Consortium Terminology
C0523509
Protein or Enzyme Type Measurement
owl:Class
CDISC SDTM Terminology
Apolipoprotein B Measurement
APOB
Apolipoprotein B Measurement
CDISC SEND Terminology
C74734
C0079247
A procedure in which multilocus band patterns of a DNA sample are generated by digestion of the DNA with restriction enzymes followed by electrophoresis and visualization by hybridization with probes specific for repetitive sequences. In forensic medicine, the probes used are "core" sequences specific for simple tandem-repetitive sequences (minisatellite repeats or VNTRs). The multilocus band patterns, known as DNA fingerprints, are evaluated for similarities with DNA from an individual.
Laboratory Procedure
DNA Fingerprinting
DNA Fingerprinting
DNA Fingerprinting
C17350
Molecular Biology Research Technique
owl:Class
DNA Analysis
DNA Fingerprinting
Gel Electrophoresis
owl:Class
Two Dimensional Gel Electrophoresis
C16538
A laboratory procedure in which proteins are first separated across a gel, usually polyacrylamide, according to their isoelectric point, and then separated in a perpendicular direction on the basis of their molecular weight.
2-D Gel Electrophoresis
Two Dimensional Gel Electrophoresis
2 Dimensional Gel Electrophoresis
Laboratory Procedure
Two Dimensional Gel Electrophoresis
Molecular Biology Research Technique
Two Dimensional Gel Electrophoresis
C0013860
CDISC SDTM Terminology
CDISC
CDISC SDTM Laboratory Test Terminology by Code
Vacuolated Neutrophil Count
Vacuolated Neutrophil Count
C74628
The determination of the number of neutrophils containing small vacuoles present in a sample.
owl:Class
Vacuolated Neutrophil Count
NEUTVAC
CL384272
Laboratory Procedure
Vacuolated Neutrophil Count
Vacuolated Neutrophils
<def-source>CDISC</def-source><def-definition>A measurement of the neutrophils containing small vacuoles in a biological specimen.</def-definition>
Clinical Data Interchange Standards Consortium Terminology
CDISC SEND Terminology
Neutrophil Count
CDISC SDTM Laboratory Test Terminology by Name
Health and Behavior in Children
C15806
Health and Behavior in Children
Research Activity
Health and Behavior in Children
owl:Class
Health and Behavior in Children
Child Health Study
CL000444
Casts
Cast Present Or Absent
Cast Present Or Absent
CASTS
CDISC SDTM Laboratory Test Terminology by Code
CDISC
Urine Sediment Analysis Measurement
Cast Present Or Absent
CL384707
<def-source>CDISC</def-source><def-definition>A statement that indicates casts were looked for and not found in a biological specimen.</def-definition>
Clinical Data Interchange Standards Consortium Terminology
CDISC SEND Terminology
CDISC SDTM Terminology
Laboratory Procedure
Cast Present Or Absent
The determination of the presence or absence of casts in a sample.
CDISC SDTM Laboratory Test Terminology by Name
C74763
owl:Class
Action
Activation
Activate
owl:Class
Activity
Activation
Activation
C64382
CL369462
Activation
To cause something to start or to stimulate activity.
Activated
The determination of the amount of mephobarbital present in a sample.
C75366
owl:Class
Mephobarbital Measurement
Barbiturate Drug Class Measurement
Mephobarbital Measurement
Mephobarbital Measurement
Mephobarbital Measurement
C0202410
Laboratory Procedure
Activity
Recruitment
C78343
owl:Class
The process of enrolling, enlisting, or adding individuals to a group.
Recruitment
Action
Recruitment
CL387839
Recruitment
Mean of Other Group Imputation Technique
C81204
Mean of Other Group Imputation Technique
owl:Class
Quantitative Concept
Mean of Other Group Imputation Technique
The substitution of missing data with the mean value from a comparator or reference group.
Mean of Other Group Imputation Technique
Statistical Imputation
CDISC SDTM Laboratory Test Terminology by Code
Hepatitis B Viral Load PCR Measurement
CDISC SEND Terminology
Hepatitis B Viral Load PCR Measurement
Polymerase Chain Reaction
CDISC SDTM Terminology
The determination of the hepatitis B viral load in a sample using polymerase chain reaction.
HBVPCR
C74725
owl:Class
Laboratory Procedure
CL384398
HBV PCR Viral Load
CDISC
CDISC SDTM Laboratory Test Terminology by Name
Clinical Data Interchange Standards Consortium Terminology
<def-source>CDISC</def-source><def-definition>A measurement of the hepatitis B viral load in a sample using polymerase chain reaction.</def-definition>
Hepatitis B Viral Load PCR Measurement
Hepatitis B Viral Load PCR Measurement
Action
Activity
Run
CL343248
Run
C47911
Run
Run
The act of testing or performing something.
owl:Class
Method for removing extreme values from a set. Defined in documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html
Activity
CL369360
Statistical Technique
C64227
owl:Class
Remove Extremes
Remove Extremes
Remove Extremes
Remove Extremes
percutaneous transhepatic cholangiography
owl:Class
The evaluation of the liver and biliary tree using a contrast agent injected directly into the liver.
Percutaneous Transhepatic Cholangiography
Percutaneous Transhepatic Cholangiography
Percutaneous Transhepatic Cholangiography
PTC
Percutaneous Transhepatic Cholangiography
C0203085
C17641
Diagnostic Procedure
Cholangiography
<def-source>NCI-GLOSS</def-source><def-definition>(per-kyoo-TAN-ee-us trans-heh-PAT-ik ko-LAN-jee-AH-gra-fee). A procedure to x-ray the hepatic and common bile ducts. A contrasting agent is injected into the liver or bile duct, and the ducts are then x-rayed to find the point of obstruction.</def-definition>
Instruction Imperative
C64641
CL370227
Let It Be Taken
Let It Be Taken
owl:Class
Qualitative Concept
Sumat
Let It Be Taken
Let It Be Taken
Microdose
Microdose
Microdose
A required drug quantity that is less than 1/100th of a typical drug dosage. Despite the smaller quantity, microdrug administration still achieves the desired pharmalogic effect.
CL357712
Microdose
Dose
C54195
owl:Class
Conceptual Entity
Regulatory Assessment
C82478
No Attending Veterinarian
Intellectual Product
NO ATTENDING VETERINARIAN
No Attending Veterinarian
No Attending Veterinarian
No Attending Veterinarian
owl:Class
C15923
Cancer Research
CGAP
The Cancer Genome Anatomy Project (CGAP) is an interdisciplinary program to establish the information and technological tools needed to decipher the molecular anatomy of a cancer cell. The Cancer Genome Anatomy Project (CGAP) will unite the newest technologies, along with those both cost-effective and capable of high-throughput, to identify all the genes responsible for the establishment and growth of cancer. CGAP has two overall goals: 1. Enhance discovery of the acquired and inherited molecular changes in cancer. 2. Evaluate the clinical potential of these discoveries. This requires the creation and dissemination of technologies that can read and interpret the molecular features of cancer.
CL003121
Cancer Genome Anatomy Project
Cancer Genome Anatomy Project
owl:Class
Cancer Genome Anatomy Project
Research Activity
Cancer Genome Anatomy Project
ostomy
C15290
Surgical creation of an opening in an organ.
surgical construction of a stoma
owl:Class
Ostomy
Surgical Procedure by Method
<def-source>MSH2001</def-source><def-definition>Surgical construction of an artificial opening (stoma) for external fistulization of a duct or vessel by insertion of a tube with or without a supportive stent.</def-definition>
Procedure_Has_Target_Anatomy only Organ
Ostomy
C0029473
Ostomy
Therapeutic or Preventive Procedure
Ostomy
<def-source>NCI-GLOSS</def-source><def-definition>(AHS-toe-mee) An operation to create an opening (a stoma) from an area inside the body to the outside. Colostomy and urostomy are types of ostomies.</def-definition>
Embedding
C48163
Embed
owl:Class
CL342172
Embed Technique
To surround an object with a firm chemical substance such as wax or resin, in order to perform cutting of thin sections for microscopic examination.
Laboratory Procedure
Embedded
Embedding
Embedding
Embedding
Tissue Processing Technique
Action
C72886
The act of hindering or obstructing or impeding.
CL383312
owl:Class
Activity
Interference
Interference
Interference
Interference
C19549
Health Education
Education of Caregivers
Education of Caregivers
Education of Caregivers
CL004757
Education of Caregivers
owl:Class
Educational Activity
therapy, low-LET implant
Low-LET Implant Therapy
Therapeutic or Preventive Procedure
Low-LET Implant Therapy
owl:Class
CL029154
Radiation Therapy
C15456
Low-LET Implant Therapy
Low-LET Implant Therapy
Interleukin 27 Measurement
CDISC SDTM Laboratory Test Terminology by Name
owl:Class
CDISC SDTM Laboratory Test Terminology by Code
The determination of the amount of interleukin 27 present in a sample.
CDISC SEND Terminology
INTLK27
Cytokine Measurement
<def-definition>A measurement of the interleukin 27 in a biological specimen.</def-definition><def-source>CDISC</def-source>
Interleukin 27 Measurement
Interleukin 27 Measurement
CDISC SDTM Terminology
Interleukin 27 Measurement
C74824
Clinical Data Interchange Standards Consortium Terminology
Laboratory Procedure
Interleukin 27
CL384305
CL030494
testicular cancer early detection
early detection of testicular cancer
Screening for Testicular Cancer
C15552
owl:Class
Cancer Screening
Diagnostic Procedure
Screening for Testicular Cancer
testicular cancer screening
Screening for Testicular Cancer
Screening for Testicular Cancer
CL104069
owl:Class
Laboratory Procedure
Total Carnitine Measurement
CARNIT
CDISC SDTM Laboratory Test Terminology by Name
C74682
Vitamin Measurement
Total Carnitine Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the total carnitine in a biological specimen.</def-definition>
The determination of the amount of total carnitine present in a sample.
CDISC
Clinical Data Interchange Standards Consortium Terminology
Carnitine
CDISC SDTM Laboratory Test Terminology by Code
Total Carnitine Measurement
Total Carnitine Measurement
CDISC SEND Terminology
CDISC SDTM Terminology
owl:Class
Newborn Screening
C15220
C0011900
diagnosis
<def-source>NCI-GLOSS</def-source><def-definition>The process of identifying a disease by the signs and symptoms.</def-definition>
Diagnosis
Diagnostic Procedure
Diagnosis
Diagnosis
Diagnosis
Dx
Diagnosed
The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation.
Diagnostic Procedure
Diagnostic
Total Basophil Count
CDISC
CDISC SDTM Terminology
The determination of the absolute number of basophils in a blood sample.
Total Basophil Count
Basophils
BASO
Leukocyte Count
CDISC SDTM Laboratory Test Terminology by Name
C0200641
CDISC SEND Terminology
Total Basophil Count
owl:Class
Clinical Data Interchange Standards Consortium Terminology
Total Basophil Count
CDISC SDTM Laboratory Test Terminology by Code
<def-definition>A measurement of the basophils per unit of a biological specimen.</def-definition><def-source>CDISC</def-source>
Laboratory Procedure
C64470
Surgical removal of part or all of the colon.
C0009274
owl:Class
Colectomy
Colon and Rectal Surgery
C15209
Colectomy
Colectomy
<def-source>NCI-GLOSS</def-source><def-definition>(ko-LEK-toe-mee) An operation to remove the colon. An open colectomy is the removal of the colon through a surgical incision made in the wall of the abdomen. Laparoscopic-assisted colectomy uses a thin, lighted tube attached to a video camera. It allows the surgeon to remove the colon without a large incision.</def-definition>
colectomy
Therapeutic or Preventive Procedure
Colectomy
Procedure_Has_Excised_Anatomy only Colon
owl:Class
C0199961
Whole Blood Transfusion
Whole Blood Transfusion
Therapeutic or Preventive Procedure
Blood Transfusion
C62749
Whole Blood Transfusion
Whole Blood Transfusion
Spectroscopy
X-Ray Photoelectron Spectroscopy
X-Ray Photoelectron Spectroscopy
Laboratory Procedure
This technique provides elemental and chemical information about the surface region (first 1-30 monolayers) of nearly any solid material, is sensitive to all elements except hydrogen, and can provide some chemical information about the valence state of elements.
C78871
Electron Spectroscopy for Chemical Analysis
ESCA
X-Ray Photoelectron Spectroscopy
XPS
A quantitative spectroscopic technique that both determines the identities and percent composition of elements in a material and measures the elemental chemical and electronic states for a sample. The process, which occurs in a vacuum, involves the irradiation of the material of interest with a beam of aluminum or magnesium X-rays while measuring both the kinetic energy and number of electrons that are released from the outer surface.
X-Ray Photoelectron Spectroscopy
CL387747
Soft, mono-energetic x-rays illuminate a region of the sample and photoelectrons emanating from it are energy-analyzed. When coupled with an ion gun, depth profiling can be performed.
owl:Class
Research Activity
owl:Class
Hypofractionated Radiation Therapy
C62726
Hypofractionated Radiation Therapy
CL365611
Hypofractionated Radiation Therapy
Radiation Therapy
Therapeutic or Preventive Procedure
Hypofractionated Radiation Therapy
CL000811
Radiation Non-Ionizing, Diagnostic Imaging
Diagnostic Imaging
Radiation Non-Ionizing, Diagnostic Imaging
Diagnostic Procedure
The use of non-ionizing radiation such as X-rays to obtain internal images of the body
owl:Class
Radiation Non-Ionizing, Diagnostic Imaging
C18981
Radiation Non-Ionizing, Diagnostic Imaging
C0202436
owl:Class
Oxazepam Measurement
Oxazepam Measurement
Oxazepam Measurement
Laboratory Procedure
C75375
Benzodiazepine Measurement
The determination of the amount of oxazepam present in a sample.
Oxazepam Measurement
Examination of the luminal surface of the sigmoid colon, using a flexible fiberoptic endoscope.
Sigmoidoscopy
Flexible Fiberoptic Sigmoidoscopy
Therapeutic or Preventive Procedure
Diagnostic Procedure
CL353404
Flexible Fiberoptic Sigmoidoscopy
Flexible Fiberoptic Sigmoidoscopy
Flexible Fiberoptic Sigmoidoscopy
owl:Class
C51588
C80408
Diagnostic Procedure
Cardiac Diagnostic Procedure
owl:Class
A study using radioisotope tagged blood components and a nuclear scanning machine to monitor the blood flow to the myocardium during or immediately following exercise.
Nuclear Stress Test
Nuclear Stress Test
Nuclear Stress Test
Nuclear Stress Test
Cancer Diagnosis
Cancer Diagnosis
Cancer Diagnosis
General term for detecting and classifying cancer in patients. (from CSP94)
Diagnostic Procedure
C16213
owl:Class
Diagnosis
CL025632
Cancer Diagnosis
C68652
The formula to calculate body surface area in dogs. It is mathematically defined as: BSA (m^2) = (10.0 x Weight(g)^2/3)/1000
owl:Class
Body Surface Area Formula for Dogs
Canine
Occupational Activity
Body Surface Area Formula for Dogs
Body Surface Area Formula for Dogs
Body Surface Area Formula for Dogs
BSA Formula for Dogs
Canis (lupus) familiaris BSA Formula
CL374287
Body Surface Area Formula
Buffy Coat Preparation
Hematology Test
A process using centrifugation of whole blood to obtain a white blood cell layer highly enriched for neutrophils, lymphocytes, monocytes and progenitor cells.
owl:Class
C72895
Laboratory Procedure
Buffy Coat Isolation
Buffy Coat Preparation
CL383085
Buffy Coat Preparation
Buffy Coat Preparation
C74727
owl:Class
Polymerase Chain Reaction
HIV Viral Load PCR Measurement
CDISC SDTM Laboratory Test Terminology by Code
HIV Viral Load PCR Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the HIV viral load in a specimen using polymerase chain reaction.</def-definition>
The determination of the HIV viral load in a specimen using polymerase chain reaction.
HIV PCR Viral Load
CL384392
CDISC SDTM Terminology
Laboratory Procedure
HIV Viral Load PCR Measurement
HIV Viral Load PCR Measurement
CDISC
HIVPCR
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
Clinical Data Interchange Standards Consortium Terminology
Population-Based Statistic
C53365
Quantitative Concept
Complete Prevalence
Complete Prevalence
owl:Class
Complete Prevalence
Complete Prevalence
CL355868
Matched Sampling
Matched Sampling
owl:Class
Quantitative Concept
C71505
Nonrandom Sampling
C0681880
Matched Sampling
Matched Sampling
Purposive Sampling
C0007836
Action
Certification
The process by which a person demonstrates specific knowledge, skills, or abilities in the view of a certifying body. Similarly, the process by which a product or process can achieve certification indicating its suitability for a specific purpose.
Certified
Certification
Certification
Certification
C43610
owl:Class
Activity
Activity
A methodical examination or review of a condition or situation.
owl:Class
Audit
C1704775
Audit
Audit
Audit
Administrative Activity
C45269
Clinical Data Interchange Standards Consortium Terminology
The determination of the amount of dopamine hormone present in a sample.
C0201989
Dopamine Measurement
<def-definition>A measurement of the dopamine hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
Dopamine Measurement
CDISC SEND Terminology
owl:Class
CDISC SDTM Terminology
Laboratory Procedure
Dopamine Measurement
Dopamine
Hormone Measurement
C74854
DOPAMINE
CDISC SDTM Laboratory Test Terminology by Name
Dopamine Measurement
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Laboratory Test Terminology by Code
PSA Assay
owl:Class
PSA
Clinical Data Interchange Standards Consortium Terminology
Prostatic Specific Antigen Measurement
Laboratory Procedure
CDISC
Prostate Specific Antigen Measurement
CDISC SDTM Terminology
CDISC SEND Terminology
Protein or Enzyme Type Measurement
Prostate Specific Antigen Measurement
Prostate Specific Antigen
Prostate Specific Antigen Measurement
C0201544
Prostate Specific Antigen Assay
C17634
CDISC SDTM Laboratory Test Terminology by Name
Prostate Specific Antigen Measurement
The determination of the prostate specific antigen present in a sample.
<def-source>CDISC</def-source><def-definition>A measurement of the prostate specific antigen in a biological specimen.</def-definition>
Statistical Technique
C53313
Statistical Distribution Characteristic
Statistical Distribution Characteristic
Probability Distribution Characteristic
owl:Class
CL355816
Statistical Distribution Characteristic
Statistical Distribution Characteristic
Characteristic of Statistical Distribution
Quantitative Concept
Therapeutic Aspiration
Therapeutic Aspiration
Therapeutic or Preventive Procedure
Aspiration
Therapeutic Aspiration
Therapeutic Surgical Procedure
C0411332
owl:Class
Therapeutic Aspiration
C65007
C82027
owl:Class
Polymorphonuclear Neutrophil Elastase Measurement
Polymorphonuclear Neutrophil Elastase Measurement
Polymorphonuclear Neutrophil Elastase Measurement
Polymorphonuclear Neutrophil Elastase Measurement
Protein or Enzyme Type Measurement
The determination of the amount of polymorphonuclear neutrophil elastase present in a sample.
CDISC SDTM Terminology
Laboratory Procedure
Glutathione-S-Transferase to Creatinine Ratio Measurement
Urine Protein Measurement
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Laboratory Test Terminology by Name
C79435
Glutathione-S-Transferase to Creatinine Ratio Measurement
Glutathione-S-Transferase/Creatinine
Glutathione-S-Transferase to Creatinine Ratio Measurement
owl:Class
<def-definition>A relative measurement (ratio or percentage) of the glutathione S-transferase to creatinine in a biological specimen.</def-definition><def-source>CDISC</def-source>
Glutathione-S-Transferase to Creatinine Ratio Measurement
The determination of the ratio of glutathione-s-transferase compared to creatinine present in a sample. The measurement may be expressed as a ratio or percentage.
GSTCREAT
Clinical Data Interchange Standards Consortium Terminology
CDISC SEND Terminology
Anti-androgen Therapy
A therapeutic regimen that utilizes pharmaceuticals to reduce serum levels of male sex hormones.
Hormone Deprivation Therapy
<def-source>NCI-GLOSS</def-source><def-definition>Treatment with drugs used to block production or interfere with the action of male sex hormones.</def-definition>
CL029465
Antiandrogen Therapy
antiandrogen therapy
owl:Class
Antiandrogen Treatment
Antiandrogen Therapy
Hormone-Deprivation Therapy
Endocrine Drug Therapy
Antiandrogen Therapy
Anti-androgen Treatment
C15481
Antiandrogen Therapy
Therapeutic or Preventive Procedure
Androgen Deprivation Therapy
ADT
Research Activity
owl:Class
Multi-Institutional Clinical Trial
Multi-Institutional Clinical Trial
multicenter study
CDISC
Clinical Data Interchange Standards Consortium Terminology
Multi-Institutional Clinical Trial
multicenter trial
<def-source>CDISC</def-source><def-definition>Clinical trial conducted according to a single protocol but at more than one site, and, therefore, carried out by more than one investigator. [ICH E9 Glossary]</def-definition>
Clinical Data Interchange Standards Consortium Glossary Terminology
C16104
Clinical Study by Organizational Parameters
CL008734
Clinical Trial
Multi-Institutional Clinical Trial
Phase I Treatment
C82081
Therapeutic or Preventive Procedure
Interceptive Treatment
Orthodontic Treatment
Interceptive Treatment
Interceptive Treatment
Orthodontic treatment designed to take advantage of the active growth stage of a child&apos;s development in order to intercept orthodontic problems early and reduce or eliminate them.
Early Interceptive Treatment
owl:Class
Interceptive Treatment
Statistical Test
Statistical Test
Statistical Test
Statistical Technique
Quantitative Concept
C0237913
A test used to determine the statistical significance of an observation.
C53228
owl:Class
Hypothesis Test
Statistical Test
Statistical Hypothesis Test
Consent Withdrawn
Consent Withdrawn
Withdraw
C48271
Regulation or Law
owl:Class
When the permission to do something is rescinded or withdrawn.
Consent Withdrawn
CL343388
Consent Withdrawn
C16855
Scanning Electron Microscopy
owl:Class
Microscopy, Electron, Scanning
Scanning Electron Microscopy
Technique of electron microscopy in which the specimen is coated with heavy metal and then scanned by an electron beam. The resolution is not as great as with transmission electron microscopy, but preparation is easier (often by fixation followed by critical point drying), the depth of focus is relatively enormous, the surface of a specimen can be seen (though not the interior unless the specimen is cracked open) and the image is aesthetically pleasing.
Scanning Electron Microscopy
C0026020
Laboratory Procedure
Scanning Electron Microscopy
Electron Microscopy
Rapid Antigen Test
Rapid Antigen Test
Rapid Antigen Test
C53465
An immunoassay that can quickly detect the presence of specific antigens in a sample and return results during a patient visit.
Rapid Antigen Test
CL357088
RAT
Immunology Test
owl:Class
Laboratory Procedure
owl:Class
Cancer Therapeutic Procedure
Cancer Pain Management
CL031441
Cancer Pain Management
Therapy directed toward reduction and control of cancer pain.
Therapeutic or Preventive Procedure
management of cancer pain
Cancer Pain Management
Cancer Pain Management
C15633
Electrophoresis
Electrophoresis
C0013855
The motion of charged particles in a colloid under the influence of an electric field; particles with a positive charge go to the cathode and negative to the anode.
C16536
Fractionation, Electrophoretic
Electrophoresis
Molecular Genetic Technique
<def-source>MSH2001</def-source><def-definition>An electrochemical process in which macromolecules or colloidal particles with a net electric charge migrate in a solution under the influence of an electric current.</def-definition>
owl:Class
Biomolecule Separations Technology
Molecular Biology Research Technique
Electrophoresis
owl:Class
Tumor Cell Graft
Research Activity
C22490
Tumor Cell Graft
Organism Modification
CL100930
Tumor Cell Graft
Tumor Cell Graft
Tumor Cell Graft
Clinical Data Interchange Standards Consortium Terminology
Lymphocytes Atypical/Leukocytes
<def-definition>A relative measurement (ratio or percentage) of the atypical lymphocytes to leukocytes in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Laboratory Test Terminology by Code
Atypical Lymphocyte to Leukocyte Ratio
C64819
CDISC SDTM Laboratory Test Terminology by Name
Atypical Lymphocyte to Leukocyte Ratio
Atypical Lymphocyte to Leukocyte Ratio
CDISC
Atypical Lymphocyte to Leukocyte Ratio
CL370126
owl:Class
LYMATLE
CDISC SEND Terminology
CDISC SDTM Terminology
Laboratory Procedure
The determination of the ratio of atypical lymphocytes to leukocytes in a blood sample. The measurement may be expressed as either a ratio or a percentage.
Blood Cell Count Ratio Measurement
owl:Class
Lymphoscintigraphy
C0412375
C67262
Lymphoscintigraphy
Diagnostic Procedure
Radionuclide Imaging
Lymphoscintigraphy
Lymphoscintigraphy
Peer-reviewed Scientific Project
Research Activity
C39491
owl:Class
Peer-reviewed Scientific Project
The peer-reviewed scientific project is one which proposal was reviewed by experts in the field who are not part of the project staff (in some cases, are not affiliated with the submitting institution), and do not have any conflicts of interest that could bias their opinions. The number of reviewers, the reviewing procedures and criteria, and the use made of the reviewers' opinions may vary, and therefore each reviewing organization/committee has to publicly disclose its policies.
Peer-reviewed Scientific Project
CL323588
Peer-reviewed Scientific Project
Research Activity
owl:Class
Tumor Infiltrating Lymphocyte Therapy
CL030138
Tumor Infiltrating Lymphocyte Therapy
C15524
Leukocyte Therapy
Tumor Infiltrating Lymphocyte Therapy
Therapeutic or Preventive Procedure
Tumor Infiltrating Lymphocyte Therapy
Maintenance Therapy
Maintenance Therapy
<def-source>NCI-GLOSS</def-source><def-definition>Treatment that is given to help a primary (original) treatment keep working. Maintenance therapy is often given to help keep cancer in remission.</def-definition>
Chemotherapy
Maintenance Therapy
C15688
Therapeutic or Preventive Procedure
Maintenance Therapy
owl:Class
C0677908
maintenance therapy
Controlling
owl:Class
Activity
C61299
Action
Control
Control
Controlled
Instruction Imperative
C0243148
Control
The act of directing or determining; regulation or maintenance of a function or action; a relation of constraint of one entity (thing or person or group) by another.
Control
<def-source>MSH2001</def-source><def-definition>The simultaneous, or near simultaneous, transference of heart and lungs from one human or animal to another.</def-definition>
Heart Lung Transplantation
Organ Transplantation
C0018833
Heart-Lung Transplantation
C15247
Heart and Lung Transplantation
Heart and Lung Transplantation
Heart and Lung Transplantation
Heart and Lung Transplantation
Heart Lung Grafting
Therapeutic or Preventive Procedure
Heart-Lung Grafting
owl:Class
Any of various techniques to reduce the expression of a gene without eliminating it entirely. The reduced epression may be permanent or via a transient mechanism.
CL384280
Gene Knockdown
Molecular Genetic Technique
owl:Class
Gene Knockdown
C74927
Gene Knockdown
Molecular Biology Research Technique
Gene Knockdown
owl:Class
Activity
C71902
Quarantine
Place into enforced isolation.
Quarantine
Quarantine
Quarantine
C0034386
Action
Glutamic Acid Decarboxylase 2 Antibody Measurement
Glutamic Acid Decarboxylase 2 Antibody Measurement
owl:Class
Protein or Enzyme Type Measurement
Glutamic Acid Decarboxylase 2 Antibody Measurement
Glutamic Acid Decarboxylase 2 Antibody Measurement
C82017
The determination of the amount of glutamic acid decarboxylase 2 antibody present in a sample.
C16859
Ultraviolet Microscopy
Ultraviolet Microscopy
Ultraviolet Microscopy
Ultraviolet Microscopy
Microscopy, Ultraviolet
Light Microscopy
<def-source>MSH2001</def-source><def-definition>Microscopy in which the image is formed by ultraviolet radiation and is displayed and recorded by means of photographic film.</def-definition>
owl:Class
Laboratory Procedure
C0026026
The study and photographing of microscope specimens in ultraviolet light. It is particularly useful when all parts of the specimen viewed are equally transparent in the visible region. (The Photonics Dictionary)
<def-source>NCI-GLOSS</def-source><def-definition>(pro-fih-LAK-tik KRAY-nee-ul ir-ray-dee-AY-shun) Radiation therapy to the head to reduce the risk that cancer will spread to the brain.</def-definition>
C15913
Prophylactic Cranial Irradiation
Prophylactic Cranial Irradiation
Central Nervous System Prophylaxis
owl:Class
Prophylactic Cranial Irradiation
PCI
Cranial Irradiation
prophylactic cranial irradiation
Prophylactic Cranial Irradiation
CL002672
Therapeutic or Preventive Procedure
Anticonvulsant Therapy
C64172
Supportive Care
C0521306
Anticonvulsant Therapy
Anticonvulsant Therapy
Anticonvulsant Therapy
Antiseizure Therapy
Drug treatment to prevent, stop, or reduce the severity of seizures or convulsions, commonly used in cases of epilepsy or other seizure disorders.
owl:Class
Therapeutic or Preventive Procedure
Discussion
An extended communication (often interactive) dealing with some particular topic.
Discussion
Organism Function
Communication
Discussion
Discussion
C71323
owl:Class
CL377754
Ovarian Ablation
Drug treatment to block the action of the female hormone estrogen.
Antiestrogen Therapy
Endocrine Drug Therapy
C15757
Antiestrogen Therapy
CL032518
It is used in high-risk breast cancer patents and as a form of treatment in selected ovarian cancers.
Therapeutic or Preventive Procedure
Antiestrogen Therapy
Antiestrogen Therapy
owl:Class
Hepatic Artery Embolization
Hepatic Artery Embolization
C66902
C0397761
Therapeutic or Preventive Procedure
Hepatic Artery Embolization
owl:Class
Hepatic Artery Embolization
Arterial Embolization
Health Care Activity
Survey Administration
Survey Administration
owl:Class
Survey Administration
Survey Administration
CL369365
Informational Intervention
C64252
Crude Survival
Crude Survival
CL355872
C53368
owl:Class
Quantitative Concept
Crude Survival
Survival
Crude Survival
Surgical creation of an opening into the maxillary antrum.
Maxillary Antrostomy
Therapeutic or Preventive Procedure
Head and Neck Surgery
Procedure_Has_Partially_Excised_Anatomy only Mucosa
Maxillary Antrostomy
Procedure_Has_Partially_Excised_Anatomy only Maxilla
CL354718
Maxillary Antrostomy
C51886
owl:Class
Maxillary Antrostomy
Partial Cystectomy
CL353583
owl:Class
Partial Cystectomy
Therapeutic or Preventive Procedure
C51636
Cystectomy
Partial Cystectomy
Partial Cystectomy
Procedure_Has_Partially_Excised_Anatomy only Bladder
Therapeutic or Preventive Procedure
CL031836
Drug Resistance Inhibition Treatment
Multidrug Resistance Inhibition
<def-source>NCI-GLOSS</def-source><def-definition>Treatment used to make cancer cells less resistant to anticancer drugs.</def-definition>
Drug Resistance Inhibition Treatment
Drug Resistance Inhibition Treatment
owl:Class
multidrug resistance inhibition
multi-drug resistance inhibition
C15689
Therapeutic Procedure
Drug Resistance Inhibition Treatment
C81281
owl:Class
Laboratory Procedure
Newborn Screening
The determination of the ratio of phenylalanine compared to tyrosine present in a sample. The measurement may be expressed as a ratio or percentage.
Amino Acid Ratio Measurement
Phenylalanine to Tyrosine Ratio Measurement
Phenylalanine to Tyrosine Ratio Measurement
Phenylalanine to Tyrosine Ratio Measurement
Phenylalanine to Tyrosine Ratio Measurement
Freezing
The act or event which causes the transition from a liquid to solid matter phase.
Freezing
Action
Activity
Freezing
Freezing
C48160
Frozen
Freeze Technique
CL342177
owl:Class
Freeze
Therapeutic Aspiration
Ultrasonic Surgical Aspiration
C65006
Therapeutic Ultrasonic Surgical Aspiration
CL370564
Therapeutic Ultrasonic Surgical Aspiration
Therapeutic Ultrasonic Surgical Aspiration
Therapeutic or Preventive Procedure
owl:Class
Therapeutic Ultrasonic Surgical Aspiration
Nicotine Dependence/Addiction on Treatment
owl:Class
Nicotine Dependence/Addiction on Treatment
C15985
CL003964
Clinical Study by Targeted Disease or Condition
Nicotine Dependence/Addiction on Treatment
Research Activity
Research Studies that assess the behavioral and/or pharmacological treatment of individuals for nicotine dependence/addiction. The specific focus of treatment interventions is the individual in clinical and physician-based settings. (NCI/TRIP)
Nicotine Dependence/Addiction on Treatment
Ames Assay
Ames Assay
Ames Assay
Mutagenicity Test
CL096372
C16235
Laboratory Procedure
An in vivo assay test used to determine if an agent, such as a chemical, is capable of causing mutations in living organisms, and if so, the strength of its mutagenic activity. The procedure uses animal tissue to create active metabolites of the substance which are then tested on bacteria.
Ames Assay
owl:Class
The surgical removal of all or part of the foot.
Amputation of Foot
owl:Class
Therapeutic or Preventive Procedure
Amputation of Foot
Amputation of Foot
CL354925
C51937
Amputation of Foot
Amputation
Rapid Plasma Reagin Measurement
CDISC SDTM Laboratory Test Terminology by Name
C0201405
Immunology Test
Rapid Plasma Reagin Measurement
CDISC SEND Terminology
C74716
owl:Class
Laboratory Procedure
<def-source>CDISC</def-source><def-definition>A measurement of the antibodies produced by cellular damage caused by Treponema pallidum (syphilis) in a biological specimen.</def-definition>
Rapid Plasma Reagin
Clinical Data Interchange Standards Consortium Terminology
Rapid Plasma Reagin Measurement
RPR
CDISC
The determination of the antibodies produced by cellular damage caused by Treponema pallidum present in a sample.
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Terminology
Rapid Plasma Reagin Measurement
Catheter Management
C15517
Supportive Care
owl:Class
Catheter Management
Catheter Management
CL034083
Catheter Management
management of catheter
Therapeutic or Preventive Procedure
CL364903
Multi-Angle Laser Light Scattering
Multi-Angle Laser Light Scattering
Static Light Scattering
A static light scattering technique involving measurement of the amount of light scattered by a suspension at multiple angles relative to the incident laser beam. Masses and the root mean square radius or a measure of geometric size can be determined using this technique on a mega Dalton scale.
Multi-Angle Laser Light Scattering
Multi-Angle Laser Light Scattering
owl:Class
MALLS
Laboratory Procedure
C62324
Refuse
owl:Class
To decline to do, accept, give, or allow something.
C49161
Refuse
CL355996
Refuse
Refused
Action
Refuse
Activity
Digital Tomosynthesis Mammography
Diagnostic Procedure
Digital Tomosynthesis Mammography
Digital Tomosynthesis Mammography
Digital Mammography
CL375787
C70761
owl:Class
Digital Tomosynthesis Mammography
Total Testosterone Measurement
CDISC SEND Terminology
Total Testosterone Measurement
C0202227
Hormone Measurement
Total Testosterone Measurement
Total Testosterone Measurement
CDISC
Testosterone
The determination of the amount of free and bound testosterone present in a sample.
C74793
CDISC SDTM Terminology
owl:Class
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Code
TESTOS
<def-source>CDISC</def-source><def-definition>A measurement of the total (free and bound) testosterone in a biological specimen.</def-definition>
C19044
Quantitative Concept
Statistical Technique
owl:Class
Statistical Technique
Statistical Technique
CL000938
Statistical Method
Technique
A method of analyzing or representing statistical data; a procedure for calculating a statistic.
Statistical Technique
Therapeutic or Preventive Procedure
The restoration of lost mineral constituents to the enamel, dentin, or cementum.
C52578
Remineralization
Remineralization
Dental Procedure
CL356512
owl:Class
Remineralization
Remineralization
Educational Intervention
Educational Intervention
An educational activity that is intended to prevent disease or alter the course of a disease in a patient or population.
Educational Activity
Educational Intervention
Intervention, Educational
Education for Intervention
owl:Class
C17874
CL030475
Educational Intervention
Informational Intervention
Esophagogastroscopy
Esophagogastroscopy
owl:Class
Diagnostic Procedure
Gastrointestinal Endoscopy
C51644
Procedure_Has_Target_Anatomy only Esophagus
Esophagogastroscopy
CL355106
Esophagogastroscopy
Procedure_Has_Target_Anatomy only Stomach
Therapeutic or Preventive Procedure
Endoscopic examination of the esophagus and stomach.
Therapeutic or Preventive Procedure
Cancer Prevention Vaccination
Cancer Prevention Vaccination
Cancer Prevention
C63337
Cancer Prevention Vaccination
owl:Class
CL365236
Cancer Prevention Vaccination
CL016029
Transurethral Electrovaporization of the Prostate
Transurethral Electrovaporization of the Prostate
Transurethral Prostatic Resection
Transurethral Electrovaporization of the Prostate
Therapeutic or Preventive Procedure
C16188
TUVP
Application of electrical energy to electrosurgically vaporize or remove the obstructive enlarged prostatic tissue. In electrosurgical vaporization, the electrode rapidly heats the tissue cells so that they turn into steam, leaving a space where the prostate tissue was previously present. (from Columbia University Department of Urology)
owl:Class
Transurethral Electrovaporization of the Prostate
Nutrition, Dietary Components
Nutrition, Minerals
Nutrition, Minerals
Nutrition, Minerals
CL003176
Research Activity
C15926
Role of minerals in cancer causation or prevention and in general health.
Nutrition, Minerals
owl:Class
C0201802
Laboratory Procedure
Specific Gravity
Assay
C64832
The density (mass per unit volume) of any material divided by that of water at a standard temperature.
owl:Class
<def-source>CDISC</def-source><def-definition>A ratio of the density of a fluid to the density of water.</def-definition>
CDISC SEND Terminology
Specific Gravity
Clinical Data Interchange Standards Consortium Terminology
SPGRAV
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
CDISC
Specific Gravity
CDISC SDTM Laboratory Test Terminology by Name
Specific Gravity
Mathematical Derivation
Mathematical Derivation
To determine by mathematical computation.
Derivation
Activity
Mathematical Derivation
C69271
Derived
<def-source>DICOM</def-source><def-definition>Method of deriving or calculating a measured value (e.g., mean, or maximum of set).</def-definition>
CL375346
owl:Class
Mathematical Derivation
Action
C81997
Segmented Neutrophil Count
Segmented Neutrophil Count
The determination of the amount of segmented neutrophils present in a sample.
Segmented Neutrophil Count
Segmented Neutrophil Count
Neutrophil Count
owl:Class
Spread
Spread
The act of extending over a wider scope or expanse of space or time.
Activity
Spread
Instruction Imperative
Action
Spread
CL385603
Spreading
owl:Class
C61404
owl:Class
CL018802
Any of the activities associated with tobacco smoking.
Individual Behavior
Smoking Behavior
Smoking Behavior
Personal Behavior
Smoking Behavior
Smoking, Tobacco and Cancer-Behavior
Smoking Behavior
C20134
Intramural Research
Research Activity
Intramural Research
owl:Class
Research Activity
Research that takes place on the NCI campus.
Intramural Research
C16103
Intramural Research
CL008730
retropubic prostatectomy
<def-source>NCI-GLOSS</def-source><def-definition>(re-tro-PYOO-bik pros-ta-TEK-toe-mee) Surgery to remove the prostate through an incision made in the abdominal wall.</def-definition>
C0194823
Retropubic Prostatectomy
Retropubic Prostatectomy
Retropubic Prostatectomy
Prostatectomy
C15401
Retropubic Prostatectomy
owl:Class
Therapeutic or Preventive Procedure
owl:Class
TAES
Transcutaneous Acupoint Electrical Stimulation
Transcutaneous Acupoint Electrical Stimulation
A non-invasive form of TENS where the gel pads are placed on acupoints and stimulation is alternated between low-intensity/high frequency and high-intensity/low frequency (dense disperse). (from White, Li, and Chiu)
C21028
Electroanalgesia
Transcutaneous Acupoint Electrical Stimulation
CL100599
Transcutaneous Acupoint Electrical Stimulation
Therapeutic or Preventive Procedure
Imaging Guided Biopsy
Image Guided Biopsy
C15652
Diagnostic Procedure
The removal of tissue specimens or fluid from the living body for microscopic examination, performed to establish a diagnosis, using imaging technology.
Image Guided Biopsy
Image-Guided Biopsy
Biopsy
owl:Class
Procedure_Has_Excised_Anatomy only Organ
Image Guided Biopsy
Image Guided Biopsy
C0456852
A method for reducing bias in which half of the treatment arrays swap with half of the control arrays in each permutation.
owl:Class
CL369237
Balanced Permutation
Qualitative Concept
C64218
Balanced Permutation
Balanced Permutation
Balanced Permutation
Statistical Test
C51768
Nasopharyngeal Biopsy
Procedure_Has_Partially_Excised_Anatomy only Nasopharynx
Removal of tissue from the nasopharynx for microscopic examination.
CL354443
Biopsy of Nasopharynx
Biopsy of Nasopharynx
owl:Class
Biopsy
Diagnostic Procedure
Biopsy of Nasopharynx
Biopsy of Nasopharynx
C17633
Laboratory Procedure
Restriction Fragment Length Polymorphism Analysis
Restriction Fragment Length Polymorphism Analysis
Use of restriction fragment polymorphism for detection of point mutations or other chromosomal changes.
Polymorphism Analysis
Restriction Fragment Length Polymorphism Analysis
owl:Class
Restriction Fragment Length Polymorphism Analysis
C0200930
owl:Class
Thermography
Thermography
Diagnostic Procedure
A diagnostic technique using a thermograph to record the heat produced by different parts of the bod. It can be used to study blood flow and to detect tumors.
Thermography
Imaging Technique
C0039810
<def-source>MSH2001</def-source><def-definition>Measurement of the regional temperature of the body or an organ by infrared sensing devices, based on self-emanating infrared radiation.</def-definition>
C17194
Thermography
owl:Class
Diagnostic Trial
Diagnostic Trial
Diagnostic Trial
Trial Indication Type
C15733
Research Activity
<def-source>NCI-GLOSS</def-source><def-definition>A research study that evaluates methods of detecting disease.</def-definition>
CL032129
diagnostic trial
Health Care Activity
Diagnostic Trial
Clinical evaluation of the utility of diagnostic procedures.
Clinical Trials, Diagnosis
owl:Class
Indican Measurement
The determination of the amount of indican present in a sample.
C82044
Indican Measurement
Urine Chemistry Measurement
Indican Measurement
Indican Measurement
Transference
Transference
Action
Transference
C79893
Transference
Activity
owl:Class
The displacement of activities or cognitive content from one area to another.
Immunoglobulin Measurement
Immunoglobulin M Measurement
Immunoglobulin M Measurement
C81972
Immunoglobulin M Measurement
The determination of the amount of immunoglobulin M present in a sample.
Immunoglobulin M Measurement
owl:Class
Vitamin B1
CL384438
CDISC SDTM Laboratory Test Terminology by Name
Vitamin B1 Measurement
C74896
Thiamine
The determination of the amount of Vitamin B1 present in a sample.
Vitamin Measurement
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Terminology
Vitamin B1 Measurement
Vitamin B1 Measurement
owl:Class
Clinical Data Interchange Standards Consortium Terminology
<def-definition>A measurement of the thiamine in a biological specimen.</def-definition><def-source>CDISC</def-source>
Vitamin B1 Measurement
VITB1
Laboratory Procedure
CDISC SEND Terminology
Prior Anthracycline Therapy
Prior Anthracycline
Clinical Attribute
Prior Anthracycline Usage
Prior Therapy
CL029115
Prior Anthracycline Therapy
Prior Anthracycline Therapy
owl:Class
Prior Anthracycline Therapy
C15451
Intraventricular Infusion Procedure
<def-source>NCI-GLOSS</def-source><def-definition>The delivery of a drug into a space within an organ.</def-definition>
Infusion Procedure
CL032172
owl:Class
Intraventricular Infusion Procedure
Intraventricular Infusion Procedure
intraventricular infusion
C15737
Intraventricular Infusion Procedure
Therapeutic or Preventive Procedure
Intraventricular Infusion
Diversion Program
Diversion Program
Behavioral Intervention
A type of program designed to assist individuals and families to address diverse issues such as alcohol and drug abuse, child disobedience, behavioral deviations, misdemeanor and felony. Essential components of the program include but are not limited to: information and referral, case management, advocacy, short term support, help in identifying and assessing the services most appropriate to meet the needs of the individual and family. The program helps to guide each individual towards a positive understanding, acceptance and change of the problems at hand whereby the health and safety of the public is maintained.
Educational Activity
Diversion Program
C41190
Diversion Program
Health Care Activity
C0680744
owl:Class
Diagnostic Procedure
Core Biopsy
Core Biopsy of Pancreas
Biopsy of Pancreas
CL353286
Core Biopsy of Pancreas
C51489
owl:Class
Core Biopsy of Pancreas
Core Needle Biopsy of Pancreas
Core Biopsy of Pancreas
The removal of pancreatic tissue using a needle with a relatively large diameter, for microscopic examination.
Interleukin 19
The determination of the amount of interleukin 19 present in a sample.
INTLK19
Cytokine Measurement
C74815
CDISC SDTM Laboratory Test Terminology by Code
Interleukin 19 Measurement
<def-definition>A measurement of the interleukin 19 in a biological specimen.</def-definition><def-source>CDISC</def-source>
Interleukin 19 Measurement
Clinical Data Interchange Standards Consortium Terminology
CDISC SEND Terminology
CDISC SDTM Terminology
CL384296
Interleukin 19 Measurement
owl:Class
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Name
Interleukin 19 Measurement
C67227
Maintenance
CL371793
Software Maintenance
Software Maintenance
All program coding after initial deployment to correct coding errors, enhance the functionality of the software, and perfect the functioning of the software.
Software Maintenance
owl:Class
Professional or Occupational Group
Software Maintenance
Packed Red Blood Cell Transfusion
C0199962
C15409
Therapeutic or Preventive Procedure
Packed Red Blood Cell Transfusion
owl:Class
PRBC Transfusion
Packed Red Blood Cell Transfusion
Packed Red Blood Cell Transfusion
Blood Transfusion
C18760
Biologic Sample Preservation Procedure
Embryo Preservation
Laboratory Procedure
owl:Class
Embryo Preservation
Embryo Preservation
Embryo Preservation
CL000341
Methods for short term or long term preservation of embryos at the two cell stage or beyond. Examples include short term storage in buffered media with serum at reduced temperature and long term cryopreservation in liquid nitrogen.
Diagnostic Surgical Procedure
CL370148
Thoracoscopic Surgery
Diagnostic Thoracoscopic Surgery
Diagnostic Thoracoscopic Surgery
C64997
Diagnostic Thoracoscopic Surgery
Diagnostic Thoracoscopic Surgery
owl:Class
Diagnostic Procedure
Color Assessment
C64546
CDISC SDTM Laboratory Test Terminology by Name
COLOR
Laboratory Procedure
Clinical Data Interchange Standards Consortium Terminology
CDISC SEND Terminology
CL370600
Color Assessment
<def-source>CDISC</def-source><def-definition>A measurement of the color of a biological specimen.</def-definition>
Color Assessment
A qualitative assessment of the color of a biological specimen.
Mixed Category Laboratory Procedure
owl:Class
CDISC
Color Assessment
Color
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
owl:Class
<def-source>NCI-GLOSS</def-source><def-definition>Radiation therapy in which high-energy rays are aimed at a tumor from many angles in a single treatment session.</def-definition>
Stereotactic Radiosurgery
Therapeutic or Preventive Procedure
Gamma Knife
Gamma Knife Radiosurgery
Gamma Knife
Gamma Knife
C0086330
Gamma Knife
C15382
gamma knife
Applied Research
C16147
Natural History
Natural History
The systematic account of natural phenomena; in medicine, the elucidation and description of disease progress.
Natural History
CL014318
Natural History
owl:Class
Occupational Activity
Serum VLDL Cholesterol Measurement
Serum VLDL Cholesterol Measurement
C0428461
VLDL Cholesterol
Laboratory Procedure
Lipid Measurement
CDISC SDTM Laboratory Test Terminology by Code
C64806
CDISC
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Terminology
owl:Class
Serum VLDL Cholesterol Measurement
Serum Chemistry Measurement
A quantitative measurement of the amount of very-low-density-lipid (VLDL) cholesterol present in a sample of serum.
CDISC SDTM Laboratory Test Terminology by Name
VLDL
CDISC SEND Terminology
<def-source>CDISC</def-source><def-definition>A measurement of the very low density lipoprotein cholesterol in a biological specimen.</def-definition>
Serum VLDL Cholesterol Measurement
Calprotectin Measurement
The determination of the amount of calprotectin present in a sample.
Calprotectin Measurement
owl:Class
C82005
Calprotectin Measurement
Protein or Enzyme Type Measurement
Calprotectin Measurement
owl:Class
CL365069
Micellar Template-Mediated Nanoparticle Synthesis
Non-Clinical Nanoparticle Application
C62393
Micelle Template Nanoparticle Synthesis
Activity
Micellar Template-Mediated Nanoparticle Synthesis
Micellar Template-Mediated Nanoparticle Synthesis
Micellar Template-Mediated Nanoparticle Synthesis
Creation of a template utilized in the preparation of certain nanoparticles. The polar heads of long chain amphipathic molecules are attached to a physical support. The non-polar tails serve as a template for nanoparticle synthesis.
Early Detection
owl:Class
Diagnostic Procedure
Prevention, Early Detection of Premalignant Lesions
CL000753
C15842
A procedure that includes screening, diet and behavioral adjustments to prevent and/or detect the transformation of normal cells into cancerous lesions.
Prevention, Early Detection of Premalignant Lesions
Prevention, Early Detection of Premalignant Lesions
Prevention, Early Detection of Premalignant Lesions
modulation, drug
Drug Modulation
C15488
CL029489
Therapeutic or Preventive Procedure
Drug Modulation
Drug Modulation
owl:Class
Drug Modulation
Drug Development
Protein or Enzyme Type Measurement
Apolipoprotein CIII Measurement
C82001
The determination of the amount of apolipoprotein CIII present in a sample.
Apolipoprotein CIII Measurement
owl:Class
Apolipoprotein CIII Measurement
Apolipoprotein CIII Measurement
In pediatrics (and some adult care), providing choices of treatment modalities, times of treatment, and other aspects of care within limits to give the patient a feeling of control and decreases feelings of helplessness associated with the treatment or care.
Choice and Control
owl:Class
Choice and Control
Choice and Control
Choice and Control
CL102863
C21000
Health Care Activity
Healthcare Activity
Total Thyroidectomy
C51762
CL354283
Procedure_Has_Completely_Excised_Anatomy only 'Thyroid Gland'
Surgery involving the complete excision of the thyroid gland.
Thyroidectomy
Total Thyroidectomy
Total Thyroidectomy
Total Thyroidectomy
Therapeutic or Preventive Procedure
owl:Class
Monoblast to Leukocyte Ratio Measurement
Blood Cell Count Ratio Measurement
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Laboratory Test Terminology by Name
owl:Class
Clinical Data Interchange Standards Consortium Terminology
CL384416
Monoblast to Leukocyte Ratio Measurement
Monoblast to Leukocyte Ratio Measurement
Laboratory Procedure
The determination of the ratio of monoblast cells compared to leukocytes present in a sample. The measurement may be expressed as a ratio or percentage.
Monoblasts/Leukocytes
CDISC SDTM Terminology
MONOBLLE
CDISC SEND Terminology
C74646
Monoblast to Leukocyte Ratio Measurement
CDISC
<def-definition>A relative measurement (ratio or percentage) of the monoblasts to leukocytes in a biological specimen.</def-definition><def-source>CDISC</def-source>
Digital Rectal Examination
An examination that checks for abnormalities of organs or other structures in the pelvis and lower abdomen. During a digital rectal exam, a health professional inserts a lubricated, gloved finger of one hand into the rectum and may use the other hand to press on the lower abdomen or pelvic area.
Digital Rectal Examination
<def-source>NCI-GLOSS</def-source><def-definition>Digital rectal examination. An examination in which a doctor inserts a lubricated, gloved finger into the rectum to feel for abnormalities.</def-definition>
Physical Examination
digital rectal examination
CL330222
Digital Rectal Examination
<def-source>NCI-GLOSS</def-source><def-definition>DRE. An examination in which a doctor inserts a lubricated, gloved finger into the rectum to feel for abnormalities.</def-definition>
DRE
owl:Class
C17631
Diagnostic Procedure
Digital Rectal Examination
Genotypic Risk Ratio
owl:Class
Risk Estimate
Genotypic Risk Ratio
Quantitative Concept
CL008151
Genotypic Risk Ratio
C19644
Genotypic Risk Ratio
Therapeutic or Preventive Procedure
High-Dose Rate Brachytherapy
High-Dose Rate Brachytherapy
High-Dose Rate Brachytherapy
owl:Class
High-Dose Rate Brachytherapy
Quantitative Concept
Radiation Brachytherapy
C0454270
C15651
C0042196
vaccination
Administration of vaccines to stimulate the host's immune response. This includes any preparation intended for active immunological prophylaxis or treatment.
Vaccination
C15346
<def-source>NCI-GLOSS</def-source><def-definition>Treatment with a vaccine.</def-definition>
Therapeutic or Preventive Procedure
owl:Class
Vaccination
Active Immunization
Vaccination
Vaccination
C15189
Procedure_Has_Excised_Anatomy only Organ
owl:Class
Biopsy
C0005558
Diagnostic Procedure
<def-source>NCI-GLOSS</def-source><def-definition>(BY-op-see) The removal of cells or tissues for examination under a microscope. When only a sample of tissue is removed, the procedure is called an incisional biopsy or core biopsy. When an entire lump or suspicious area is removed, the procedure is called an excisional biopsy. When a sample of tissue or fluid is removed with a needle, the procedure is called a needle biopsy or fine-needle aspiration.</def-definition>
Biopsy
Biopsy
The removal of tissue specimens or fluid from the living body for microscopic examination, performed to establish a diagnosis.
Diagnostic Procedure
biopsy
Biopsy
C16169
Prior Surgery
CL014623
Prior Surgery
Clinical Attribute
owl:Class
Prior Surgery
Prior Surgery
Prior Therapy
Therapeutic or Preventive Procedure
Abdominal Panniculectomy
Abdominal Panniculectomy
C51597
Abdominal Surgical Procedure
CL354874
Procedure_Has_Partially_Excised_Anatomy only 'Adipose Tissue'
Surgical removal of excess skin and adipose tissue from the abdomen.
owl:Class
Procedure_Has_Partially_Excised_Anatomy only Skin
Abdominal Panniculectomy
Abdominal Panniculectomy
Intervention Strategies
An activity that produces an effect, or that is intended to alter the course of a disease in a patient or population. This is a general term that encompasses the medical, social, behavioral, and environmental acts that can have preventive, therapeutic, or palliative effects.
Procedure
<def-source>CDISC</def-source><def-definition>A particular course of action intended to achieve a result. (NCI)</def-definition>
SURGICAL AND MEDICAL PROCEDURES
Intervention or Procedure
CDISC
Interventional
C0184661
Intervention
Intervention or Procedure
owl:Class
C25218
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Terminology
Clinical or Research Activity
CDISC SDTM System Organ Class Terminology
Intervention or Procedure
Health Care Activity
Intervention or Procedure
CL001009
Research Activity
owl:Class
Translational Science
Translational Research
Translational Research
Translational Research
Studies designed to translate basic science findings into clinically useful tools and applications.
C15862
Translational Research Enterprise
Translational Research
Research Activity
C15285
Nursing Research
Clinical research carried out by nurses.
C0028695
Research Activity
Nursing Research
Nursing Research
Clinical Study by Organizational Parameters
owl:Class
Nursing Research
Surgery involving partial excision of the tongue.
CL354138
Partial Glossectomy
Procedure_Has_Partially_Excised_Anatomy only Tongue
C51911
Therapeutic or Preventive Procedure
Partial Excision of Tongue
Partial Excision of Tongue
Partial Excision of Tongue
Glossectomy
owl:Class
Partial Excision of Tongue
CL000449
Health Promotion and Care-Work Site
Health Promotion and Care-Work Site
C18831
Health Promotion and Care
Health Promotion and Care-Work Site
Programs at the work site to promote health (e.g., anti-smoking).
Health Promotion and Care-Work Site
Health Care Activity
owl:Class
Statistical Distribution
A representation (usually a graph or plot) showing the likelihood that particular event will occur over a set of values. The representation may be defined by a mathematical function, the probability density function.
Statistical Distribution
Statistical Distribution
owl:Class
Statistical Distribution
C0038205
Quantitative Concept
Statistics Distributions
Statistical Technique
C53206
Activity
CL378206
Taper
C71482
Taper
Taper
To cease by degrees; decrease; diminish.
Taper Off
Action
owl:Class
Taper
CL355819
C53354
owl:Class
Trend in Rates
Trend in Rates
Trend in Rates
Trend in Rates
Population-Based Statistic
Quantitative Concept
CDISC SEND Terminology
<def-source>CDISC</def-source><def-definition>A measurement of the tropomyosin binding troponin in a biological specimen.</def-definition>
Troponin T Measurement
Clinical Data Interchange Standards Consortium Terminology
C1141947
owl:Class
Protein or Enzyme Type Measurement
Troponin T Measurement
CDISC
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Laboratory Test Terminology by Code
Laboratory Procedure
Troponin T
Troponin T Measurement
The determination of the amount of troponin T present in a blood sample.
CDISC SDTM Terminology
C74750
TROPONT
Troponin T Measurement
adjuvant therapy
owl:Class
Any therapy that is administered to augment or stimulate other treatment modalities or to minimize or prevent disease recurrence subsequent to the main treatment plan.
<def-source>NCI-GLOSS</def-source><def-definition>(AD-joo-vant) Treatment given after the primary treatment to increase the chances of a cure. Adjuvant therapy may include chemotherapy, radiation therapy, hormone therapy, or biological therapy.</def-definition>
Adjuvant Therapy
Therapeutic or Preventive Procedure
Adjuvant Therapy
Adjuvant Therapy
CL031797
C15675
Adjuvant Therapy
Cancer Therapeutic Procedure
Rat Transgene
Rat Transgene
Organism Modification
Rat Transgene
Rat Transgene
Rat Transgene
C22496
Modification of a rat by transgenic techniques.
CL100933
Research Activity
owl:Class
Infusion Procedure
Intracarotid Infusion Procedure
Intracarotid Infusion
Intracarotid Infusion Procedure
Intracarotid Infusion Procedure
owl:Class
Therapeutic or Preventive Procedure
CL032171
C15736
<def-source>NCI-GLOSS</def-source><def-definition>The introduction of fluids and drugs directly into the carotid artery, the main artery in the neck that carries blood from the heart to the brain.</def-definition>
Intracarotid Infusion Procedure
intracarotid infusion
Amniocentesis
Diagnostic Procedure
Paracentesis
owl:Class
C52009
Amniocentesis
Diagnostic Aspiration
Amniocentesis
A prenatal diagnostic procedure in which a small sample of amniotic fluid is removed from the uterus by a needle inserted into the abdomen. This procedure is used to detect various genetic abnormalities in the fetus and/or the sex of the fetus.
C0002627
Amniocentesis
Therapy Preparation
Therapeutic Procedure
owl:Class
CL369198
C64256
Therapy Preparation
Health Care Activity
Therapy Preparation
Therapy Preparation
CL323416
Active Funded Research Project
Active Funded Research Project
A research project that is in an active grant funding cycle.
C39303
Active Funded Research Project
Research Activity
owl:Class
Research Activity
Active Funded Research Project
Thyroid Antibody Measurement
The determination of the amount of thyroid antibodies present in a sample.
Thyroid Antibody Measurement
C81990
Immunology Test
Thyroid Antibody Measurement
Thyroid Antibody Measurement
owl:Class
owl:Class
HIV Measurement
Laboratory Procedure
C79102
HIV Measurement
HIV Measurement
CL387717
Immunology Test
HIV Measurement
Supportive Care
Drug Extravasation Therapy
owl:Class
CL029916
C15513
drug extravasation management
Therapeutic or Preventive Procedure
Drug Extravasation Therapy
Drug Extravasation Therapy
Drug Extravasation Therapy
Direct Fluorescent Antibody Test
Laboratory Procedure
DFA
An immunoassay in which a fluorescent-labeled antibody binds directly to a target antigen.
Direct Fluorescent Antibody Test
CL357470
Immunology Test
Direct Fluorescent Antibody Test
C53467
owl:Class
Direct Fluorescent Antibody Test
C0200591
Intra-Operative Blood Salvage Autotransfusion
Intra-Operative Blood Salvage Autotransfusion
intraoperative blood salvage
Intra-Operative Blood Salvage Autotransfusion
C15580
Autotransfusion Procedure
Intra-Operative Blood Salvage
Therapeutic or Preventive Procedure
Intra-Operative Blood Salvage Autotransfusion
owl:Class
Health Care Activity
Clinical Service
C15785
Clinical Service
Clinical Service
C0557854
owl:Class
Healthcare Activity
Clinical Service
Services
C68647
Dubois and Dubois Body Surface Area Formula
Dubois and Dubois Body Surface Area Formula
Dubois and Dubois Body Surface Area Formula
Dubois and Dubois BSA Formula
Body Surface Area Formula
Dubois and Dubois Body Surface Area Formula
owl:Class
CL374438
Occupational Activity
The formula to calculate body surface area as described by D and EF DuBois. It is mathematically defined as: BSA (m^2) = 0.20247 x [Height(m)^0.725] x [Weight(kg)^0.425]
Dubois and Dubois
C0014441
Laboratory Procedure
A highly sensitive technique for detecting and measuring antigens or antibodies in a solution; the solution is run over a surface to which immobilized antibodies specific to the substance have been attached, and if the substance is present, it will bind to the antibody layer, and its presence is verified and visualized with an application of antibodies that have been tagged in some way. (BioTech Life Science Dictionary)
ELISA
ELISA
ELISA
ELISA
Enzyme Immunoassay
<def-source>MSH2001</def-source><def-definition>An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.</def-definition>
owl:Class
Enzyme-linked Immunosorbent Assay
C16553
Biopsy of Parathyroid Gland
Biopsy of Parathyroid Gland
Biopsy
owl:Class
C51587
Removal of parathyroid tissue for microscopic examination.
Diagnostic Procedure
Biopsy of Parathyroid Gland
Biopsy of Parathyroid Gland
Parathyroid Biopsy
CL354445
Procedure_Has_Partially_Excised_Anatomy only 'Parathyroid Gland'
Diagnostic Procedure
C70945
Biospecimen Collection
Biospecimen Collection
Biospecimen Collection
owl:Class
Diagnostic Procedure
Biospecimen Collection
CL375938
The act or process of gathering biospecimens for testing, diagnostic, propagation, treatment or research purposes.
<def-source>NCI-GLOSS</def-source><def-definition>Surgery to remove both breasts in order to reduce the risk of developing breast cancer.</def-definition>
C1706504
Prophylactic Bilateral Mastectomy
Therapeutic or Preventive Procedure
C46072
BPM
owl:Class
Mastectomy
Procedure_Has_Completely_Excised_Anatomy only 'Left Breast'
Bilateral Prophylactic Mastectomy
bilateral prophylactic mastectomy
Surgical removal of both non-diseased breasts with the goal of preventing breast carcinoma.
Bilateral Prophylactic Mastectomy
Bilateral Prophylactic Mastectomy
Bilateral Prophylactic Mastectomy
Procedure_Has_Completely_Excised_Anatomy only 'Right Breast'
C75958
Action
CL386600
Transition
Transition
Transition
A change from one state or stage to another.
Activity
Transition
owl:Class
Total Nephrectomy
Nephrectomy
Therapeutic or Preventive Procedure
CL354282
C51632
Total Nephrectomy
Procedure_Has_Completely_Excised_Anatomy only Kidney
Total Nephrectomy
Total Nephrectomy
owl:Class
Risk Assessment
Risk Assessment
Risk Assessment
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (MeSH)
Health Care Activity
Risk Assessment
C0086930
C15367
owl:Class
Healthcare Activity
Partial Pharyngectomy
Partial Pharyngectomy
CL354142
Partial Pharyngectomy
Partial Pharyngectomy
owl:Class
Therapeutic or Preventive Procedure
Procedure_Has_Partially_Excised_Anatomy only Pharynx
C51609
Surgery involving the partial excision of the pharynx.
Pharyngectomy
<def-definition>A measurement of the Vitamin B17 in a serum specimen.</def-definition><def-source>CDISC</def-source>
C74897
VITB17
Vitamin B17 Measurement
Vitamin B17 Measurement
Vitamin B17 Measurement
Vitamin B17
The determination of the amount of Vitamin B17 present in a sample.
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Terminology
Vitamin B17 Measurement
CL384437
Amygdalin
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Laboratory Test Terminology by Code
owl:Class
CDISC SEND Terminology
Vitamin Measurement
Laboratory Procedure
in vitro-Treated Bone Marrow Transplantation
antibody treated bone marrow transplantation
antibody treated bone marrow transplant
in vitro-Treated Bone Marrow Transplantation
Therapeutic or Preventive Procedure
monoclonal antibody treated bone marrow transplant
Bone Marrow Transplantation
C15462
CL029161
owl:Class
monoclonal antibody treated bone marrow transplantation
in vitro-Treated Bone Marrow Transplantation
in vitro-Treated Bone Marrow Transplantation
in vitro-treated bone marrow transplant
owl:Class
C15955
Heart Research
Research Activity
Heart Research
Research Activity
Heart Research
Heart Research
CL003375
Birth Method of Delivery
C81300
Vacuum Assisted Vaginal Delivery
Therapeutic or Preventive Procedure
Vacuum Assisted Vaginal Delivery
The method referring to the delivery of a fetus through the vaginal canal with assistance of a vacuum extractor device.
Vacuum Assisted Vaginal Delivery
Vacuum Assisted Vaginal Delivery
owl:Class
Newborn Screening
Cardiac Therapeutic Procedure
Cardiovascular Surgical Procedure
Heart Valve Repair
Heart Valve Repair
owl:Class
Heart Valve Repair
Therapeutic or Preventive Procedure
Heart Valve Repair
C50818
Surgery performed for the purpose of repairing a degenerated, calcified, malformed, dysfunctional, etc. heart valve.
Procedure_Has_Target_Anatomy only 'Cardiac Valve'
C0190112
Spawning
owl:Class
Spawning
Spawning
Breeding
Spawning
SPAWNING
C82476
Organism Attributre
Computed Tomography
<def-source>NCI-GLOSS</def-source><def-definition>A computerized image of the metabolic activity of body tissues used to determine the presence of disease.</def-definition>
Positron Emission Tomography
C17007
positron emission tomography scan
FDG-PET
Medical Imaging, Positron Emission Tomography
Positron Emission Tomography Scan
Positron Emission Tomography
Positron Emission Tomography
Diagnostic Procedure
proton magnetic resonance spectroscopic imaging
owl:Class
A technique for measuring the gamma radiation produced by collisions of electrons and positrons (anti-electrons) within living tissue. In positron emission tomography (PET), a subject is given a dose of a positron-emitting radionuclide attached to a metabolically active substance (for example, 2-fluoro-2-deoxy-D-glucose (FDG), which is similar to a naturally occurring sugar, glucose, with the addition of a radioactive fluorine atom). When living tissue containing the positron emitter is bombarded by electrons, gamma radiation produced by collisions of electrons and positrons is detected by a scanner, revealing in fine detail the tissue location of the metabolically-active substance administered.
Positron Emission Tomography
C0032743
PET scan
PET Scan
PET
Positron-Emission Tomography
Round Epithelial Cells
EPIROCE
Round Epithelial Cell Count
<def-source>CDISC</def-source><def-definition>A measurement of the round epithelial cells present in a urine specimen.</def-definition>
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
CL384426
C74698
Round Epithelial Cell Count
Epithelial Cell Count
Laboratory Procedure
CDISC
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Name
Round Epithelial Cell Count
owl:Class
Round Epithelial Cell Count
Clinical Data Interchange Standards Consortium Terminology
The determination of the number of round epithelial cells present in a urine sample.
Block Dissection of Inguinal Lymph Nodes
owl:Class
Block Dissection of Inguinal Lymph Nodes
Diagnostic Procedure
Block Dissection of Inguinal Lymph Nodes
Therapeutic or Preventive Procedure
CL353704
Inguinal Lymphadenectomy
C51620
Surgical removal of multiple adjacent, frequently adherent, inguinal lymph nodes.
Block Dissection of Inguinal Lymph Nodes
in vitro fertilization
in vitro Fertilization
C16580
in vitro Fertilization
in vitro Fertilization
<def-source>NCI-GLOSS</def-source><def-definition>A procedure in which eggs are removed from a woman's ovary and combined with sperm outside the body to form embryos. The embryos are grown in the laboratory for several days and then either placed in a woman's uterus or cryopreserved (frozen) for future use.</def-definition>
C0015915
in vitro Fertilization
Artificial Fertilization
IVF
owl:Class
Therapeutic or Preventive Procedure
Reproductive Technique
Unilateral Thyroid Lobectomy
owl:Class
Thyroid Lobectomy
Thyroid Lobectomy
CL354823
Therapeutic or Preventive Procedure
Thyroidectomy
Lobectomy of Thyroid Gland
Thyroid Lobectomy
C51649
Thyroid Lobectomy
Surgery involving complete excision of a lobe of the thyroid gland.
Procedure_Has_Completely_Excised_Anatomy only 'Thyroid Gland Lobe'
Laboratory Procedure
Cytologic Test
Cytologic Test
C49132
Cytologic Test
A diagnostic test utilized to examine and define cellular anatomy or function. The test results are often used by a clinician to diagnose disease or disordered function.
Diagnostic Procedure
owl:Class
Cytologic Test
Cytological Procedure
C0010799
Gene Transfer
Gene Transfer
Gene Transfer
owl:Class
Gene Transfer
C20185
Incorporation of new DNA into an organism's cells, usually by a vector such as a modified virus. Used in gene therapy.(From Human Genome Project Information).
CL024555
Molecular Genetic Technique
Molecular Biology Research Technique
Therapeutic Surgical Procedure
Therapeutic Procedure
Therapeutic or Preventive Procedure
Surgical Procedure
CL370561
Therapeutic Surgical Procedure
C64982
Therapeutic Surgical Procedure
owl:Class
Therapeutic Surgical Procedure
Adjuvant Chemotherapy
Adjuvant Chemotherapy
Adjuvant Therapy
Adjuvant Chemotherapy
Adjuvant Chemotherapy
owl:Class
C15360
Chemotherapy that is administered subsequent to the main treatment plan to minimize or prevent disease recurrence.
Therapeutic or Preventive Procedure
C0085533
owl:Class
CL336748
Venous Sampling
Venous Sampling
Venous Sampling
Venous Sampling
Diagnostic Procedure
Diagnostic Imaging
C62664
Breast Cancer Education
CL000126
Breast Cancer, Education
Health Education
Programs or materials to provide information on breast cancer prevention, detection, or treatment to health professionals, patients and their families, the public, or high-risk groups.
Breast Cancer Education
C18662
owl:Class
Breast Cancer Education
Breast Cancer Education
Educational Activity
CL355981
Procedure_Has_Partially_Excised_Anatomy only 'Sternocleidomastoid Muscle'
Procedure_Has_Completely_Excised_Anatomy only 'Submandibular Gland'
Therapeutic or Preventive Procedure
Neck Dissection
C51759
Radical Neck Dissection
Procedure_Has_Partially_Excised_Anatomy only 'Internal Jugular Vein'
Radical Neck Dissection
Radical Neck Dissection
Radical Neck Dissection
owl:Class
An activity that attempts to find the best solution to a problem.
C78561
Optimization
Optimization
CL387564
Optimization
Optimization
Action
owl:Class
Activity
owl:Class
Serum Uric Acid Measurement
C61034
Serum Uric Acid Measurement
C0455272
Serum Uric Acid Measurement
Laboratory Procedure
Serum Chemistry Measurement
Serum Uric Acid Measurement
A quantitative measurement of the amount of uric acid present in a sample of serum.
C0027741
The use of anesthetics in the central or peripheral nervous system to diminish or eliminate the bombardment of the CNS with nociceptive input, which minimizes stress response, adverse spinal reflexes, and wind-up. It may be performed for temporary or permanent pain palliation. (from Rowlingson)
nerve block
Nerve Block
Therapeutic or Preventive Procedure
Neural Block
Neural Block
<def-source>NCI-GLOSS</def-source><def-definition>A procedure in which medicine is injected directly into or around a nerve or into the spine to block pain.</def-definition>
<def-source>MSH2002_06_01</def-source><def-definition>Interruption of the conduction of impulses in peripheral nerves or nerve trunks by the injection of a local anesthetic solution. (Stedman, 26th ed)</def-definition>
owl:Class
Neural Blockade
Neural Block
C21072
Neural Block
Regional Anesthesia Procedure
The measurement of radiation by photography, as in x-ray film and film badge, by Geiger-Mueller tube, and by scintillation counting.
dosimetry
owl:Class
C15312
Radiation Dosimetry
C0034603
Activity
Radiation Dosimetry
Radiation Dosimetry
Radiation Dosimetry
<def-source>NCI-GLOSS</def-source><def-definition>(doh-SIH-muh-tree) Measurement of radiation exposure from x-rays, gamma rays, or other types of radiation used in the treatment or detection of diseases, including cancer.</def-definition>
Dosimetry
Technique
CDISC SEND Terminology
CL384302
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
<def-definition>A measurement of the interleukin 24 in a biological specimen.</def-definition><def-source>CDISC</def-source>
The determination of the amount of interleukin 24 present in a sample.
Interleukin 24 Measurement
Laboratory Procedure
C74821
INTLK24
Interleukin 24 Measurement
Clinical Data Interchange Standards Consortium Terminology
Cytokine Measurement
CDISC SDTM Laboratory Test Terminology by Name
owl:Class
Interleukin 24 Measurement
Interleukin 24
Interleukin 24 Measurement
Respiratory Rate
Respiratory Rate
Quantitative Concept
CDISC
Clinical Data Interchange Standards Consortium Terminology
Respiratory Rate
C49678
CDISC SDTM Terminology
owl:Class
<def-source>CDISC</def-source><def-definition>The rate of breathing (inhalation and exhalation) measured within in a unit time, usually expressed as breaths per minute. (NCI)</def-definition>
CDISC SDTM Vital Sign Terminology by Code
Newborn Screening
Respiratory Rate
The rate of breathing (inhalation and exhalation) measured within in a unit time, usually expressed as breaths per minute.
CDISC SDTM Vital Sign Terminology by Name
Vital Signs
RESP
C0231832
The determination of the amount of cellular casts present in a urine sample.
C74764
Clinical Data Interchange Standards Consortium Terminology
Cellular Cast Measurement
CDISC SDTM Laboratory Test Terminology by Name
Cellular Cast Measurement
CDISC SDTM Laboratory Test Terminology by Code
CDISC
CDISC SEND Terminology
Laboratory Procedure
CDISC SDTM Terminology
Cellular Cast Measurement
Cellular Cast Measurement
Urine Sediment Analysis Measurement
Cellular Casts
CL384755
owl:Class
<def-source>CDISC</def-source><def-definition>A measurement of the cellular (white blood cell, red blood cell, epithelial and bacterial) casts present in a urine specimen.</def-definition>
CSCELL
C74607
CD3 Expressing T Cell Count
CL384375
CD3 Expressing T Cell Count
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
<def-source>CDISC</def-source><def-definition>A count of the CD3 T cells per unit of a biological specimen.</def-definition>
CD3
The determination of the number of CD3 expressing T cells present in a sample.
Laboratory Procedure
CDISC
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
Lymphocyte Count
owl:Class
CD3 Expressing T Cell Count
CD3 Expressing T Cell Count
Laboratory Procedure
Osmolarity Measurement
Chemistry Test
Osmolarity Measurement
Osmolarity Measurement
The determination of the osmoles of solute per liter of solution present in a sample.
Osmolarity Measurement
owl:Class
C0201804
C74802
A statistical distribution described by a function whose range may assume any value, typically any value in the set of real numbers.
owl:Class
CL356425
Continuous Distribution
Continuous Distribution
Continuous Distribution
C53213
Continuous Distribution
Statistical Distribution
Quantitative Concept
Analytical and separative procedures in which molecules, particularly proteins or nucleic acids, are separated by their different electrophoretic mobilities in a hydrated gel. The gel suppresses convective mixing of the fluid phase through which the electrophoresis takes place and contributes molecular sieving. For proteins, commonly carried out in the presence of the anionic detergent sodium dodecylsulphate (SDS). SDS denatures proteins so that noncovalently associating sub unit polypeptides migrate independently and by binding to the proteins confers a net negative charge roughly proportional to the chain weight.
Polyacrylamide Gel Electrophoresis
Fractionation, Polyacrylamide Gel
<def-source>MSH2001</def-source><def-definition>Electrophoresis in which a polyacrylamide gel is used as the diffusion medium.</def-definition>
C0013862
owl:Class
PAGE
Polyacrylamide Gel Electrophoresis
Gel Electrophoresis
Molecular Biology Research Technique
Polyacrylamide Gel Electrophoresis
Polyacrylamide Gel Electrophoresis
Laboratory Procedure
C16539
Electrophoresis, Polyacrylamide Gel
Gene Cloning
C0009017
Gene Cloning
C16443
Gene Cloning
Molecular Biology, Gene Cloning
The insertion of a DNA sequence into a vector that can then be propagated in a host organism, generating a large number of copies of the sequence.
Gene Cloning
Cloning
Molecular Biology Research Technique
owl:Class
Total Radical-Trap Antioxidant Potential Measurement
Total Radical-Trap Antioxidant Potential Measurement
Total Radical-Trap Antioxidant Potential Measurement
Total Radical-Trap Antioxidant Potential Measurement
The determination of the potential for the antioxidants contained in a biological specimen to buffer free radicals in a solution.
Laboratory Procedure
C80208
owl:Class
Serum Chemistry Measurement
Activity
Action
owl:Class
Centralized
Centralization
Centralization
C0680827
The act of consolidating power under a central control; the process by which the activities of an organization, particularly those regarding decision-making; become concentrated within a particular location and/or group.
Centralization
C53278
Centralization
owl:Class
Laboratory Procedure
<def-source>MSH2001</def-source><def-definition>Chromatography on non-ionic gels without regard to the mechanism of solute discrimination.</def-definition>
Column Chromatography
Gel Filtration Chromatography
Gel Filtration Chromatography
Gel permeation or sieve chromatography that is performed on porous gels that separate solutes on the basis of size. Smaller solutes are included within the particles of the gel matrix more frequently than larger solutes, thus affecting elution rates.
Gel Permeation Chromatography
Gel Filtration Chromatography
Size Exclusion Chromatography
C0008559
C16433
Gel Filtration Chromatography
<def-source>CDISC</def-source><def-definition>A measurement of the sulfa crystals present in a urine specimen.</def-definition>
CL384427
Crystal Growth Measurement
owl:Class
CDISC SDTM Laboratory Test Terminology by Name
Urine Chemistry Measurement
CDISC SDTM Terminology
Sulfa Crystal Measurement
Laboratory Procedure
Sulfa Crystals
C74755
CDISC SEND Terminology
Sulfa Crystal Measurement
The determination of the amount of sulfa crystals present in a urine sample.
CDISC
CYSULFA
CDISC SDTM Laboratory Test Terminology by Code
Sulfa Crystal Measurement
Sulfa Crystal Measurement
Clinical Data Interchange Standards Consortium Terminology
C54699
Market Withdrawal
Market Withdrawal
CL360674
Remedial Action
Market Withdrawal
owl:Class
Market Withdrawal
Activity
A removal or correction by manufacturer or owner of a marketed product that the FDA considers to be either no violation or in minor violation of the laws it administers, and against which the agency would not initiate legal action. The concept does not refer to redemption or liquidation of stocks issued by the company.
owl:Class
Shipping
Shipping
Action
Activity
CL337322
The act or business of transporting goods.
Shipping
C40353
Shipping
Quick Freeze
Freezing
Flash Freeze
Quick Freeze
Flash Frozen
Snap Frozen
CL366246
C63521
Quick Frozen
Snap Freeze
To freeze rapidly so as to preserve structure and prevent ice crystal formation.
Quick Freeze
owl:Class
Activity
Quick Freeze
Action
Activity
Deny
owl:Class
Deny
Denial
Denied
CL384447
Refuse to accept, recognize or acknowledge.
Deny
C74933
Deny
Population Distribution Characteristic
owl:Class
CL355785
Population Distribution Characteristic
Population Distribution Characteristic
C53314
Population Distribution Characteristic
Statistical Distribution Characteristic
Characteristic of Population Distribution
Quantitative Concept
Linker-Scanning Mutagenesis
Linker-Scanning Mutagenesis
Laboratory Procedure
Linker-Scanning Mutagenesis
owl:Class
In vitro mutagenesis procedure in which molecules containing 3' and 5' deletion mutations are combined to regenerate an entire DNA region, differing with the wild type molecule only at the junction of the molecules, which contains a linker DNA.
CL083942
Mutagenesis
C20627
Linker-Scanning Mutagenesis
Alpha Naphthyl Butyrate Esterase Stain
Alpha Naphthyl Butyrate Esterase Staining Method
Alpha Naphthyl Butyrate Esterase Staining Method
C28416
Alpha Naphthyl Butyrate Esterase Staining Method
Alpha Naphthyl Butyl Esterase Staining Method
owl:Class
A cytochemical staining technique used to detect esterase enzyme contained within monocytes and macrophages, which reacts strongly with the substrate alpha-naphthyl butyrate. Monoblastic [FAB M5a (without differentiation) or M5b (with differentiation)] and acute myelomonocytic (M4) leukemias blasts stain when the butyrate substrate is used. Myeloid cells (either malignant or non-malignant) do not stain with nonspecific esterase techniques.
Alpha Naphthyl Esterase Staining Method
Laboratory Procedure
Alpha Naphthyl Butyrate Esterase Staining Method
C1293962
Releasing
Released
owl:Class
C42882
Release
Qualitative Concept
Release
Release
Release
Action
C0391871
To make available; set free.
Clinical Trials: Cancer Treatment
owl:Class
Clinical Study by Targeted Disease or Condition
Clinical Trials: Cancer Treatment
Clinical Trials: Cancer Treatment
C16096
Research Activity
CL008686
Treatment Study
Clinical Trials: Cancer Treatment
Smooth Muscle Actin Staining Method
owl:Class
An immunohistochemical staining protocol for localization of actin. The antibody is specific for the alpha-smooth muscle actin present in smooth muscle cells.
Smooth Muscle Actin Staining Method
Smooth Muscle Actin Staining Method
CL100940
SMA
Smooth Muscle Actin Staining Method
Smooth Muscle Actin Staining Method
Laboratory Procedure
C23021
Smooth Muscle Actin
Special Histology Staining Method
Blood Cell Count
Plasmacytes
<def-source>CDISC</def-source><def-definition>A measurement of the mature plasma cells (plasmacytes) in a biological specimen.</def-definition>
CDISC SEND Terminology
CL384326
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Terminology
The determination of the number of mature plasma cells present in a sample.
Mature Plasma Cell Count
CDISC
owl:Class
Mature Plasma Cell Count
Mature Plasma Cell Count
Mature Plasma Cells
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
C74661
Mature Plasma Cell Count
PLSMCE
<def-source>CDISC</def-source><def-definition>A type of study protocol designed to evaluate intervention(s) aimed at identifying a disease or condition. (NCI)</def-definition>
Clinical Data Interchange Standards Consortium Terminology
Diagnosis Study
Diagnostic Study
Diagnosis Study
owl:Class
Trial Indication Type
CDISC SDTM Trial Indication Type Terminology
Diagnosis Study
CDISC
Research Activity
A type of study designed to evaluate method(s) aimed at identifying a disease or condition.
CDISC SDTM Terminology
Diagnosis Study
DIAGNOSIS
CL354488
C49653
<def-definition>A measurement of the interleukin 6 in a biological specimen.</def-definition><def-source>CDISC</def-source>
C74834
The determination of the amount of interleukin 6 present in a sample.
CDISC SDTM Laboratory Test Terminology by Code
Laboratory Procedure
Interleukin 6 Measurement
CL384316
CDISC SEND Terminology
Cytokine Measurement
owl:Class
Interleukin 6 Measurement
CDISC SDTM Terminology
Clinical Data Interchange Standards Consortium Terminology
INTLK6
Interleukin 6 Measurement
CDISC SDTM Laboratory Test Terminology by Name
Interleukin 6 Measurement
Interleukin 6
Diagnostics Research
Diagnostics Research
C15798
Research Activity
Diagnostics Research
owl:Class
Diagnostics Research
CL000306
Applied Research
Confinement to Bed
Bed Confinement
Bed Rest
Confinement of an individual to bed for therapeutic reasons.
C45985
Therapeutic Procedure
Bed Rest
Bed Rest
C0004910
owl:Class
Therapeutic or Preventive Procedure
Bed Rest
hyperfractionation
Fractionation
Hyperfractionation
Therapeutic or Preventive Procedure
Hyperfractionation
Hyperfractionation
Hyperfractionation
owl:Class
C15745
<def-source>NCI-GLOSS</def-source><def-definition>A way of giving radiation therapy in smaller-than-usual doses two or three times a day instead of once a day.</def-definition>
CL032281
Hyperfractionated Radiation
Action
Purified
The process of removing impurities.
Purification
Purification
Purifiy
owl:Class
Purification
Purification
Activity
C0243114
C68780
The act of making necessary corrections or modifications.
Adjustment
Adjusted
Activity
C0376209
Adjustment
C49157
Adjustment
owl:Class
Adjustment
Action
Exercise
Aerobic Exercise
Aerobic Exercise
C39774
Examples of aerobic exercise include running, swimming, and cycling.
Aerobic Exercise
owl:Class
Aerobic Activity
C0001701
Aerobic Exercise
Daily or Recreational Activity
Sustained exercise that places an increased oxygen demand on the cardiovascular system and promotes an increased efficiency of the body's use of oxygen.
Tumor-Targeted Bacterial Therapy
Tumor-Targeted Bacterial Therapy
C71728
Biological Therapy
Tumor-Targeted Bacterial Therapy
Tumor-Targeted Bacterial Therapy
owl:Class
CL378335
Therapeutic or Preventive Procedure
C0003611
Appendectomy
Therapeutic or Preventive Procedure
Surgical removal of the vermiform appendix.
Appendectomy
C51687
Procedure_Has_Excised_Anatomy only Appendix
Appendectomy
owl:Class
Appendectomy
Abdominal Surgical Procedure
owl:Class
C38040
The radiographic examination of the tracheobronchial tree following the injection of a radiopaque material.
Bronchography
Bronchography
Radiography
Bronchography
Diagnostic Procedure
Bronchography
C0006282
CL030700
Tumor-Draining Lymph Node Lymphocyte Therapy
Tumor-Draining Lymph Node Lymphocyte Therapy
Tumor-Draining Lymph Node Lymphocyte Therapy
C15573
owl:Class
Tumor-Draining Lymph Node Lymphocyte Therapy
Leukocyte Therapy
Therapeutic or Preventive Procedure
Isokinetic Exercise
C21059
The advantage of this exercise is that it stresses the muscle being used throughout the entire range.
Exercise
An exercise that involves movement at a constant rate with a variable force throughout a specified range of motion.
Daily or Recreational Activity
Isokinetic Exercise
Isokinetic Exercise
CL111104
Isokinetic Exercise
owl:Class
Isokinetics
C0524258
Hallucinogen Measurement
Psilocybine Measurement
Laboratory Procedure
C75356
Psilocybine Measurement
Psilocybine Measurement
owl:Class
Psilocybine Measurement
The determination of the amount of psilocybine present in a sample.
Wolfe Classification Mammography
A classification method according to Wolfe that assigns mammograms to four parenchynal patterns according to the distribution of fat and the prominence of the ducts. These patterns are again dichotomized into low-risk and high-risk patterns.
Mammography, Wolfe
CL322423
Wolfe Classification Mammography
owl:Class
Wolfe Classification Mammography
Mammography
Wolfe Classification Mammography
Diagnostic Procedure
C38072
Educational Activity
Cervical Cancer Education
C18692
Health Education
Cervical Cancer Education
Cervical Cancer Education
owl:Class
Programs or materials to provide information on cervical cancer prevention, detection, or treatment to health professionals, patients and their families, the public, or high-risk groups.
CL000198
Cervical Cancer Education
C18640
A laboratory test or analysis of the biological activity of a substance performed by studying its effect in an experimental situation outside the organism, e.g. in the test tube rather than in living systems.
Bioassay, in vitro
Laboratory Procedure
CL000091
Bioassay, in vitro
Bioassay
owl:Class
Bioassay, in vitro
Bioassay, in vitro
owl:Class
C67033
Music Therapy
Music Therapy
Music Therapy
Music Therapy
Mind-Body Intervention Procedure
C0026868
Mental Process
Immunoblot Analysis
Immunoblot Analysis
A technique for analyzing or identifying proteins immobilized on a filter by complementary reaction with specific antibodies.
Immunoblot Analysis
C0201773
Immunoblot Analysis
Laboratory Procedure
owl:Class
C17638
Immunology Test
One-Stage Cluster Random Sampling
One-Stage Cluster Random Sampling
One-Stage Cluster Random Sampling
Quantitative Concept
One-Stage Cluster Random Sampling
C71499
CL378127
owl:Class
Cluster Random Sampling
Computational Technique
Gjedde-Patlak Analysis
Patlak Plot
Activity
When the equilibrium is achieved, the plot becomes linear and the slope of the linear phase represents the net transfer rate, Ki (influx constant), the amount of accumulated tracer in relation to the amount of tracer that has been available in plasma.
A graphical analysis technique based on a two compartment model that uses linear regression to identify and analyze pharmacokinetics problems involving irreversible uptake in one compartment.
Patlak Plot
C80353
owl:Class
Gjedde-Patlak Plot
Patlak Plot
Patlak Plot
Patlak Analysis
CL051913
Assign
Assignment
C25426
An allotting or an appointment to a particular person or use, or for a particular time or object.
Conceptual Entity
Assignment
owl:Class
Assignment
Assigned
Action
Assignment
Freeze-Drying
<def-source>NCI-GLOSS</def-source><def-definition>A method used to dry substances, such as food, to make them last longer. The substance is frozen and then dried in a vacuum.</def-definition>
Freeze-Drying
Freeze-Drying
Biologic Sample Preservation Procedure
Freeze-Drying
owl:Class
A dehydration process typically used to preserve a perishable material. The specimen is frozen and then dehydrated at low temperature in a high vacuum.
Laboratory Procedure
C28150
freeze-dried
Lyophilization
C0016698
owl:Class
Breast Reconstruction
Breast Reconstruction
<def-source>MSH2001</def-source><def-definition>Surgical reconstruction of the breast including both augmentation and reduction.</def-definition>
Reconstruction
C0085076
<def-source>NCI-GLOSS</def-source><def-definition>Surgery to rebuild a breast's shape after a mastectomy.</def-definition>
Therapeutic or Preventive Procedure
Mammaplasty
C15354
Breast Reconstruction
Breast Reconstruction
breast reconstruction
Removal of tissue from the vagina or cervix by the use of a colposcope.
C15703
Colposcopic Biopsy
Procedure_Has_Partially_Excised_Anatomy only Vagina
Diagnostic Procedure
CL031904
Colposcopic Biopsy
Colposcopic Biopsy
Biopsy
owl:Class
Colposcopic Biopsy
CDISC SEND Terminology
C74653
CL384341
Blood Cell Count Ratio Measurement
Promyelocyte to Lymphocyte Ratio Measurement
Promyelocyte to Lymphocyte Ratio Measurement
Clinical Data Interchange Standards Consortium Terminology
<def-source>CDISC</def-source><def-definition>A relative measurement (ratio or percentage) of the promyelocytes (immature myelocytes) to all leukocytes in a biological specimen.</def-definition>
The determination of the ratio of promyelocytes compared to all lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
owl:Class
Promyelocyte to Lymphocyte Ratio Measurement
PROMYLE
Laboratory Procedure
Promyelocytes/Leukocytes
Promyelocyte to Lymphocyte Ratio Measurement
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
CDISC
owl:Class
C49686
<def-definition>A clinical research protocol generally referred to as a pilot or feasibility trial that aims to prove the concept of the new intervention in question. (NCI)</def-definition><def-source>CDISC</def-source>
Trial Phase IIA
Phase IIa Trial
CDISC SDTM Terminology
Phase II Trial
Trial Phase 2A
Research Activity
Phase IIa Trial
Phase IIa Trial
2A
CL356223
Clinical Data Interchange Standards Consortium Terminology
CDISC
A clinical research protocol generally referred to as a pilot or feasibility trial that aims to prove the concept of the new intervention in question.
CDISC SDTM Trial Phase Terminology
Phase IIa Trial
Diagnostic Procedure
Screening for Breast Cancer
Breast Cancer Screening
Breast Cancer Screening
owl:Class
Breast Cancer Screening
Breast Cancer Screening
Early detection of breast cancer involving asymptomatic women. Generally done in the population with higher risk, due to environmental or genetic factors.
C15546
C1536442
Cancer Screening
Activity
Translation
Action
Translation
C80450
Translation
The act or process of rendering from one language into another.
Translation
owl:Class
Procedure_Has_Target_Anatomy only Vagina
Endoscopic Procedure
Colposcopy
Colposcopy
Endoscopic examination of the uterine cervix and vagina.
C16451
colposcopy
owl:Class
Colposcopy
C0009417
Procedure_Has_Target_Anatomy only 'Cervix Uteri'
<def-source>NCI-GLOSS</def-source><def-definition>(kul-PAHS-ko-pee) Examination of the vagina and cervix using a lighted magnifying instrument called a colposcope.</def-definition>
Diagnostic Procedure
Colposcopy
C64216
Quantitative Concept
maxT
Statistical Test
maxT
maxT
maxT
A statisical test to adjust the p-value for multiple comparisons.
owl:Class
CL369218
maxT Test
Virtual Endoscopy
The use of 3D CT or MRI scans to construct a simulated visualization of patient specific organs similar or equivalent to those produced by standard endoscopic procedures. Virtual endoscopic visualization avoids the risks associated with real endoscopy. Additionally, there are many body regions not accessible to or compatible with real endoscopy that can be explored with virtual endoscopy. (from R. Robb presentation at Visible Human Project Conference)
Medical Imaging, Virtual Reality
Virtual Endoscopy
Diagnostic Procedure
owl:Class
C20097
Virtual Endoscopy
Virtual Endoscopy
CL017246
owl:Class
C64986
Therapeutic or Preventive Procedure
Vascular-Disruption Therapy
Biological Therapy
Vascular-Disruption Therapy
Vascular-Disruption Therapy
CL370370
Vascular-Disruption Therapy
C80172
Complement Bb Measurement
Laboratory Procedure
Complement Bb Measurement
Complement Measurement
Complement Bb Measurement
Complement Bb Measurement
The determination of the amount of complement Bb present in a sample.
owl:Class
owl:Class
CDISC SDTM Laboratory Test Terminology by Code
Creatine Kinase MM to Total Creatine Kinase Ratio Measurement
C79442
Creatine Kinase MM/Total Creatine Kinase
Creatine Kinase MM to Total Creatine Kinase Ratio Measurement
Laboratory Procedure
Urine Protein Measurement
CKMMCK
Clinical Data Interchange Standards Consortium Terminology
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Name
The determination of the ratio of creatine kinase MM compared to total creatine kinase present in a sample. The measurement may be expressed as a ratio or percentage.
Creatine Kinase MM to Total Creatine Kinase Ratio Measurement
<def-definition>A relative measurement (ratio or percentage) of the MM-type creatine kinase to total creatine kinase in a biological specimen.</def-definition><def-source>CDISC</def-source>
Creatine Kinase MM to Total Creatine Kinase Ratio Measurement
CDISC SDTM Terminology
CL003849
owl:Class
The growing of microbes in test tube or petri dish type environments
Culturing, in vitro Microbial
Culturing, in vitro Microbial
Culturing, in vitro Microbial
Tissue Culture
Laboratory Procedure
Culturing, in vitro Microbial
C19347
C19828
Metaphase Spread
Cytogenetic Analysis
Laboratory Procedure
Metaphase Spread
Analysis of chromosomes arrested during metaphase. The chromosomes are highly condensed at this stage of cell division and are visible under a light microscope. (From the journal Nature-Glossary).
Metaphase Spread
Metaphase Spread
CL008949
owl:Class
Screening for Neuroblastoma
neuroblastoma screening
CL031555
Screening for Neuroblastoma
early detection of neuroblastoma
Screening for Neuroblastoma
Cancer Screening
C15641
neuroblastoma early detection
owl:Class
Diagnostic Procedure
Screening for Neuroblastoma
INVESTIGATIONS
Investigation
Clinical Data Interchange Standards Consortium Terminology
Action
CDISC SDTM System Organ Class Terminology
Investigation
Investigation
The act or process of a systematic and thorough examination; research, study; the process of inquiring into or following up, intended to develop facts.
C41198
CDISC SDTM Terminology
owl:Class
CDISC
Activity
Investigation
<def-source>CDISC</def-source><def-definition>The act or process of a systematic and thorough examination; research, study; the process of inquiring into or following up, intended to develop facts. (NCI)</def-definition>
C0430007
Binomial Distribution
Quantitative Concept
Binomial Distribution
Discrete Distribution
owl:Class
Binomial Distribution
C53208
C0005463
A family of discreet probability density functions, which models systems that meet the following requirements: 1) the number of trials (n) is fixed; 2) there are only two outcomes for each trial, success or failure; 3) the outcome of each trial is independent; and 4) all trials have the same probability (p) of success. Binomial distributions show the likelihood of the number of successful trials versus the total number of trials.
Binomial Distribution
Pearson Correlation Coefficient
Statistical Technique
Pearson Correlation Coefficient
Pearson Product-moment Correlation Coefficient
CL369993
Pearson Correlation Coefficient
Activity
Pearson Correlation Coefficient
owl:Class
A measure of the correlation of two variables X and Y measured on the same object or organism, that is, a measure of the tendency of the variables to increase or decrease together. It is defined as the sum of the products of the standard scores of the two measures divided by the degrees of freedom.
C65172
C-Terminal Parathyroid Hormone Measurement
C81964
The determination of the amount of C-terminal parathyroid hormone present in a sample.
Hormone Measurement
C-Terminal Parathyroid Hormone Measurement
C-Terminal Parathyroid Hormone Measurement
C-Terminal Parathyroid Hormone Measurement
owl:Class
Therapeutic or Preventive Procedure
Local Therapy
Mixed High-Low LET Therapy
C15460
Mixed High-Low LET Therapy
Mixed High-Low LET Therapy
therapy, mixed high-low LET
Mixed High-Low LET Therapy
owl:Class
CL029158
Radiation Therapy
Diagnostic Videothoracoscopy
Diagnostic Thoracoscopy
Diagnostic Videothoracoscopy
Videothoracoscopy
owl:Class
CL370151
Diagnostic Procedure
C64949
Diagnostic Videothoracoscopy
Diagnostic Videothoracoscopy
The determination of the amount of protein present in a urine sample.
Urine Protein Measurement
Urine Chemistry Measurement
Urine Protein Measurement
Urine Protein Measurement
C74760
Laboratory Procedure
owl:Class
C0262923
Urine Protein Measurement
DNA Sequencing, Non-Human Gene Mapping
CL000413
Gene Mapping, Non-Human
Gene Mapping, Non-Human
Laboratory Procedure
Molecular Biology Research Technique
C18805
Gene Mapping, Non-Human
owl:Class
Determination of the relative positions of genes from non-human organisms on a DNA molecule (chromosome or plasmid) and of the distance, in linkage units or physical units, between them.
Gene Mapping, Non-Human
Gene Mapping
C18935
owl:Class
Phage Display
Phage Display
Phage Display
Molecular Biology Research Technique
Phage Display
CL000702
Expression Technologies for DNA and RNA
Molecular biology technique that facilitates cloning or identification of specific proteins or peptides with a specific antigenic, ligand or protein-binding, enzymatic, or other biological property. It is based on the cloning of DNA within a phage coat protein gene so that the resulting protein is expressed as a fusion expressed on the surface of the phage.
CL384284
Hormone Measurement
Growth Hormone Inhibiting Hormone Measurement
Somatostatin
GRWHIH
The determination of the amount of growth hormone inhibiting hormone present in a sample.
CDISC SEND Terminology
Growth Hormone Inhibiting Hormone
Clinical Data Interchange Standards Consortium Terminology
Growth Hormone Inhibiting Hormone Measurement
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
CDISC SDTM Terminology
Growth Hormone Inhibiting Hormone Measurement
owl:Class
Growth Hormone Inhibiting Hormone Measurement
CDISC SDTM Laboratory Test Terminology by Code
<def-definition>A measurement of the growth hormone inhibiting hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
C74861
Surgical removal of the entire liver.
Procedure_Has_Completely_Excised_Anatomy only 'Right Lobe of the Liver'
owl:Class
Hepatectomy
Total Hepatectomy
Total Hepatectomy
Therapeutic or Preventive Procedure
Procedure_Has_Completely_Excised_Anatomy only 'Left Lobe of the Liver'
Total Hepatectomy
CL354281
C51781
Procedure_Has_Completely_Excised_Anatomy only Liver
Total Hepatectomy
CDISC SDTM Laboratory Test Terminology by Code
HASAB
Laboratory Procedure
The determination of the surface antibody reaction of a sample to the Hepatitis A virus.
Hepatitis A Surface Antibody Measurement
Clinical Data Interchange Standards Consortium Terminology
<def-source>CDISC</def-source><def-definition>A measurement of the surface antibody reaction of a biological specimen to the Hepatitis A virus.</def-definition>
owl:Class
Hepatitis A Surface Antibody Measurement
CDISC SDTM Terminology
Hepatitis A Surface Antibody Measurement
C74710
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
CDISC
Hepatitis A Surface Antibody Measurement
Immunology Test
Hepatitis A Virus Surface Antibody
CL384396
Observed Survival
C53367
Survival
CL355780
Quantitative Concept
Observed Survival
Observed Survival
Observed Survival
owl:Class
Prior Therapy
An indicator that a person has been previously treated for the same condition or with the same therapy.
Prior Treatment
Prior Therapy
Prior Therapy
CL012942
C16124
owl:Class
Clinical Attribute
Clinical Trial Eligibility Criteria
Prior Therapy
Therapeutic or Preventive Procedure
Musculoskeletal Complications Management
C62744
Musculoskeletal Complications Management
owl:Class
CL365403
Musculoskeletal Complications Management
Supportive Care
Musculoskeletal Complications Management
C62674
Pharmacological Study
Pharmacological Study
owl:Class
Study
Laboratory Procedure
Pharmacological Study
Pharmacological Study
CL365423
Diaphanography
Passage of light through body tissues or cavities for examination of internal structures.
C0600353
Diaphanography
Diaphanography
Diaphanography
C18151
owl:Class
Imaging Technique
Diagnostic Procedure
Probe Correction Method
Probe Correction Method
CL369069
Probe Correction Method
C64230
A method for correcting perfect match (PM) probe expression levels. Defined in the documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html
Activity
Statistical Technique
owl:Class
Probe Correction Method
Cardiac Therapeutic Procedure
Therapeutic or Preventive Procedure
Percutaneous Transluminal Coronary Angioplasty
Percutaneous Transluminal Coronary Angioplasty
Percutaneous Transluminal Coronary Angioplasty
C0002997
A procedure to open an occluded coronary artery, performed by percutaneous introduction of a catheter into a peripheral (usually femoral) artery which is directed in a retrograde fashion to reach the diseased coronary artery.
Procedure_Has_Target_Anatomy only 'Coronary Artery'
Percutaneous Transluminal Coronary Angioplasty
C38078
owl:Class
Angioplasty
CL384360
<def-source>CDISC</def-source><def-definition>A relative measurement (ratio or percentage) of acanthocytes to all erythrocytes in a biological specimen.</def-definition>
Acanthocyte to Erythrocyte Ratio Measurement
Laboratory Procedure
The determination of the ratio of acanthocytes compared to erythrocytes present in a sample. The measurement may be expressed as a ratio or percentage.
C74633
CDISC
owl:Class
Acanthocyte to Erythrocyte Ratio Measurement
ACANTRBC
CDISC SDTM Laboratory Test Terminology by Code
CDISC SEND Terminology
CDISC SDTM Terminology
Acanthocyte to Erythrocyte Ratio Measurement
Blood Cell Count Ratio Measurement
CDISC SDTM Laboratory Test Terminology by Name
Acanthocyte to Erythrocyte Ratio Measurement
Clinical Data Interchange Standards Consortium Terminology
Acanthocytes/Erythrocytes
Pituitary Isograft
Pituitary Isograft
Pituitary Isograft
CL320068
Organism Modification
Grafting of pituitary tissue between genetically identical individuals.
Research Activity
C29898
Isogenic Pituitary Graft
owl:Class
Pituitary Isograft
Risk Estimate
Quantitative Concept
Risk Estimate
Statistical Technique
<def-source>MSH2001</def-source><def-definition>The probability that an event will occur. It encompasses a variety of measures of the probability of a generally unfavorable outcome.</def-definition>
CL000881
Compare with 'Risk'
C19015
Risk Estimate
owl:Class
Risk Estimate
Blood Cell Count Ratio Measurement
owl:Class
CL384408
The determination of the ratio of leukemic blasts compared to lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
CDISC SEND Terminology
Leukemic Blast to Lymphocyte Ratio Measurement
Leukemic Blast to Lymphocyte Ratio Measurement
CDISC SDTM Laboratory Test Terminology by Name
<def-source>CDISC</def-source><def-definition>A relative measurement (ratio or percentage) of the leukemic blasts (immature lymphoblasts) to mature lymphocytes in a biological specimen.</def-definition>
CDISC
Leukemic Blast to Lymphocyte Ratio Measurement
Leukemic Blasts/Lymphocytes
CDISC SDTM Laboratory Test Terminology by Code
BLSTLMLY
CDISC SDTM Terminology
Leukemic Blast to Lymphocyte Ratio Measurement
C74641
Laboratory Procedure
Clinical Data Interchange Standards Consortium Terminology
<def-source>MSH2001</def-source><def-definition>The preparation of leukocyte concentrates with the return of red cells and leukocyte-poor plasma to the donor.</def-definition>
Pheresis
Leukapheresis
C15269
owl:Class
Leukapheresis
Leukapheresis
C0023416
leukapheresis
Therapeutic or Preventive Procedure
<def-source>NCI-GLOSS</def-source><def-definition>Removal of the blood to collect specific blood cells; the remaining blood is returned to the body.</def-definition>
Leukapheresis
Therapeutic Leukopheresis
Leukocytopheresis
Do Not Substitute
C67004
Instruction Imperative
Do Not Substitute
CL385618
Do Not Substitute
owl:Class
Do Not Substitute
Activity
No Substitution
owl:Class
Carcinogenicity Test
Soft Agar Assay
C16215
Laboratory Procedure
Soft Agar Assay
Soft Agar Assay
Soft Agar Assay
Soft agar colony formation assay is performed to assay for anchorage independent growth.
CL026259
Tumor Replication Error Analysis
Tumor Replication Error Analysis
Tumor Replication Error Analysis
DNA Analysis
owl:Class
Molecular Biology Research Technique
Certain tumors contain widespread deletions within mono- and dinucleotide repeat sequences in their DNA, referred to as the replication error (RER+) phenotype. The RER+ status of tumors is usually determined by examining several dinucleotide and mononucleotide repeats for size variations when compared with the matching normal DNA.
Tumor Replication Error Analysis
CL032138
C18307
Laboratory Procedure
Enzyme Activation Therapy
Enzyme Activation Therapy
Therapeutic or Preventive Procedure
owl:Class
Enzyme Activation Therapy
Therapeutic Procedure
CL365572
C62719
Enzyme Activation Therapy
Clinical Data Interchange Standards Consortium Terminology
Phase V Trial
CDISC
Clinical Study by Phase
owl:Class
C47865
Postmarketing surveillance is sometimes referred to as Phase V. See outcomes research.
CL343038
Phase V Trial
<def-source>CDISC</def-source><def-definition>Postmarketing surveillance is sometimes referred to as Phase V.</def-definition>
5
CDISC SDTM Terminology
Phase V Trial
Research Activity
CDISC SDTM Trial Phase Terminology
Phase V Trial
Trial Phase 5
Vaccine Design
CL004296
owl:Class
Determining the antigens (whole virus, parts or crossreacting) to be incorporated in a vaccine
Vaccine Design
Vaccine Development
Vaccine Design
C16006
Health Care Activity
Vaccine Design
CL009734
Quadruple Phase Spiral CT
Quadruple Phase Helical CT
A type of computed tomography whereby images wihtin four separate phases following contrast medium administration are taken.
C19908
Phased Spiral CT
Quadruple Phase Spiral CT
Quadruple Phase Spiral CT
owl:Class
Diagnostic Procedure
Quadruple Phase Spiral CT
Palpation
C0030247
Physical Examination
palpation
Palpation
Diagnostic Procedure
<def-source>NCI-GLOSS</def-source><def-definition>Examination by pressing on the surface of the body to feel the organs or tissues underneath.</def-definition>
Palpation
C16950
A method of feeling with the hands during a physical examination. The health care provider touches and feels the patient's body to examine the size, consistency, texture, location and tenderness of an organ or body part.
owl:Class
Palpation
Bioassay
MGMT Methylation Assay
C79101
MGMT Methylation Assay
Laboratory Procedure
MGMT Methylation Assay
owl:Class
CL387625
MGMT Methylation Assay
Mucin-1 Staining Method
Mucin 1 Staining Method
Mucin 1
Mucin-1 Staining Method
An immunohistochemical technique used to detect the gene product of the MUC1 gene, using monoclonal antibodies directed against mucin-1 glycoprotein.
Special Histology Staining Method
Mucin-1 Staining Method
owl:Class
MUC1
CL100947
C23032
Mucin 1 Staining Method
Laboratory Procedure
Mucin-1 Staining Method
CL384434
Urine Ammonium Oxalate Crystal Measurement
CDISC SDTM Terminology
Urine Ammonium Oxalate Crystal Measurement
C74759
Laboratory Procedure
CDISC
Urine Ammonium Oxalate Crystal Measurement
CDISC SEND Terminology
Urine Chemistry Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the ammonium oxalate crystals present in a urine specimen.</def-definition>
Crystal Growth Measurement
owl:Class
Ammonium Oxalate Crystals
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
CYAMMOX
CDISC SDTM Laboratory Test Terminology by Name
The determination of the amount of ammonium oxalate crystals present in a urine sample.
Urine Ammonium Oxalate Crystal Measurement
Action
Anchorage
Activity
Anchorage
C82102
Anchorage
owl:Class
Anchorage
Resistance to activation force.
Thyrotropin Measurement
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Name
C64813
TSH
owl:Class
CDISC SEND Terminology
Thyrotropin Measurement
Thyrotropin Measurement
CDISC SDTM Terminology
Hormone Measurement
Laboratory Procedure
C0202230
CDISC
<def-source>CDISC</def-source><def-definition>A measurement of the thyrotropin in a biological specimen.</def-definition>
CDISC SDTM Laboratory Test Terminology by Code
Thyrotropin Measurement
Newborn Screening
Thyrotropin
A quantitative measurement of the amount of thyrotropin present in a sample.
C19232
Mixed Category Laboratory Procedure
Procedures utilized to save substances from decay. Some preservation procedures are meant to maintain cells, tissues, or organisms in a viable state.
Laboratory Procedure
Preservation Procedure
Preservation Procedure
Preservation Procedure
Preservation
owl:Class
C1514402
Preservation Procedure
The determination of the amount of 3,4-Methylenedioxyethamphetamine (MDEA) present in a sample.
MDEA Measurement
3,4-Methylenedioxyethamphetamine Measurement
owl:Class
3,4-Methylenedioxyethamphetamine Measurement
3,4-Methylenedioxyethamphetamine Measurement
Amphetamine Drug Class Measurement
Methylenedioxyethylamphetamine Measurement
Laboratory Procedure
CL384578
3,4-Methylenedioxyethamphetamine Measurement
C75358
The determination of the amount of unsaturated non-esterified fatty acids present in a sample.
Unsaturated Non-esterified Fatty Acids Measurement
Unsaturated Non-esterified Fatty Acids Measurement
C80209
Laboratory Procedure
owl:Class
Unsaturated Non-esterified Fatty Acids Measurement
Fatty Acid Measurement
Unsaturated Non-esterified Fatty Acids Measurement
Laminin Staining Method
Laminin Staining Method
This immunohistochemical technique is used to detect laminin, a large extracellular matrix glycoprotein, using antibody directed towards laminin. This may be useful as a marker for basement membrane integrity.
Laminin Staining Method
Laboratory Procedure
Laminin
LAM
Laminin Staining Method
Special Histology Staining Method
Laminin Staining Method
C23028
owl:Class
CL100945
Clinical Data Interchange Standards Consortium Terminology
CDISC
Large Unstained Cell Count
<def-source>CDISC</def-source><def-definition>A measurement of the large, peroxidase-negative cells which cannot be further characterized (i.e. as large lymphocytes, virocytes, or stem cells) present in a biological specimen.</def-definition>
C74659
CDISC SDTM Laboratory Test Terminology by Code
LGUNSCE
Laboratory Procedure
CDISC SDTM Terminology
Cell Count
The determination of the number of large unstained cells present in a sample.
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
Large Unstained Cell Count
C1443561
owl:Class
Large Unstained Cell Count
Large Unstained Cell Count
Large Unstained Cells
Research Activity
Cancer Control Research Program
C15952
CL003314
Cancer Research
Cancer Control Research Program
Cancer Control Research Program
owl:Class
Cancer Control Research Program
The act of validating; finding or testing the truth of something.
Validation
owl:Class
Validation
Validation
Research Activity
Clinical Testing
CL098503
Validation
C16237
Diagnostic Procedure
Intervention or Procedure
diagnostic procedure
Diagnostic Procedure
<def-source>CSP2000</def-source><def-definition>heading term for tests not treed elsewhere under DIAGNOSIS.</def-definition>
Diagnostic Procedure
<def-source>MSH2001</def-source><def-definition>Methods, procedures, and tests performed to diagnose disease, disordered function, or disability.</def-definition>
owl:Class
<def-source>NCI-GLOSS</def-source><def-definition>A method used to identify a disease.</def-definition>
Diagnostic Procedure
Diagnostic Method
C18020
Methods, procedures, and tests performed to diagnose disease, disordered function, or disability.
C0430022
Diagnostic Technique
Diagnostic Procedure
Diagnostic Test
owl:Class
Therapeutic or Preventive Procedure
Venipuncture
Patient Code (Appendix B)
Phlebotomy
<def-source>NCI-GLOSS</def-source><def-definition>The puncture of a vein with a needle for the purpose of drawing blood.</def-definition>
C0190979
Diagnostic Procedure
venipuncture
FDA
phlebotomy
Patient Problem Codes FDA CDRH
Phlebotomy
Phlebotomy
C28221
Phlebotomy
Technique used to draw blood from a vein for diagnostic purposes or for treatment of certain blood disorders. (From MSH 2002)
The joining together of two or more nucleic acid molecules by the action of ligase
DNA Ligation
Molecular Biology Research Technique
Molecular Genetic Technique
DNA Ligation
C19246
owl:Class
DNA Ligation
DNA Ligation
CL003209
Biopsy of Small Intestine
Endoscopic Biopsy
Removal of tissue from the small intestine for microscopic examination, using an endoscope.
owl:Class
C51600
Biopsy of Small Intestine
Diagnostic Procedure
Procedure_Has_Partially_Excised_Anatomy only 'Small Intestine'
Small Intestinal Biopsy
Biopsy of Small Intestine
Biopsy of Small Intestine
CL355002
Cardiac Resynchronization Therapy
Cardiac Resynchronization Therapy
C80436
Therapeutic or Preventive Procedure
Cardiac Resynchronization Therapy
owl:Class
Cardiac Resynchronization Therapy
Cardiac Therapeutic Procedure
A surgical procedure in which a pacemaker is implanted to re-coordinate the electrical activity of the right and left ventricles in patients with heart failure.
endometrial cancer early detection
Cancer Screening
Diagnostic Procedure
Screening for Endometrial Cancer
Screening for Endometrial Cancer
CL031751
early detection of endometrial cancer
owl:Class
endometrial cancer screening
C15671
Screening for Endometrial Cancer
Screening for Endometrial Cancer
owl:Class
C51784
Vaginal Hysterectomy
CL355579
Therapeutic or Preventive Procedure
Vaginal Hysterectomy
Vaginal Hysterectomy
Total Hysterectomy
A surgical procedure to remove the uterine body and cervix, via the vaginal approach.
Vaginal Hysterectomy
Procedure_Has_Target_Anatomy only Vagina
Hysterectomy, Vaginal
CAM Pharmacological or Biological Treatment
CAM Pharmacological or Biological Treatment
Pharmacological or Biological Treatment
CAM Pharmacological or Biological Treatment
owl:Class
CAM Pharmacological or Biological Treatment
Therapeutic or Preventive Procedure
Complementary or Alternative Medical Procedure
CL002439
C15906
C64805
International Normalized Ratio of Prothrombin Time
International Normalized Ratio of Prothrombin Time
International Normalized Ratio of Prothrombin Time
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Code
INR
Prothrombin Intl. Normalized Ratio
CL370441
CDISC SDTM Terminology
Laboratory Procedure
A measure of the extrinsic pathway of coagulation. The International Normalized Ratio of Prothrombin Time (INR) is the ratio of a patient prothrombin time to a normal (control) sample raised to the power of the International Sensitivity Index (ISI) with a range of 0.8 to 1.2 seconds.
Prothrombin Time
CDISC
CDISC SDTM Laboratory Test Terminology by Name
<def-source>CDISC</def-source><def-definition>A ratio that represents the prothrombin time for a plasma specimen, divided by the result for a control plasma specimen, further standardized for the International Sensitivity Index of the tissue factor (thromboplastin) used in the test.</def-definition>
owl:Class
Clinical Data Interchange Standards Consortium Terminology
International Normalized Ratio of Prothrombin Time
owl:Class
C0004400
C16314
Diagnostic Procedure
Autoradiography
Autoradiography
Autoradiography
A technique used to locate radioactively labeled molecules, or fragments of molecules, by recording on a photographic or sensor plate the radiation emitted by radioactive material within molecule.
Radiography
Autoradiography
Laboratory Procedure
Diagnostic or therapeutic use of non-ionizing radiation
Radiation Therapy
Radiation, Non-Ionizing DX or RX
Radiation, Non-Ionizing DX or RX
CL000816
C18984
Therapeutic or Preventive Procedure
Radiation, Non-Ionizing DX or RX
Radiation, Non-Ionizing DX or RX
owl:Class
Qualitative Evaluation
C49143
A type of evaluation that is primarily descriptive and interpretative, and may or may not lend itself to quantification. Mainly concerned with the properties, the state, and the character (i.e., the nature) of phenomena. It implies an emphasis on processes and meanings that are rigorously examined, but not measured in terms of quantity, amount, or frequency. (www.unfpa.org/monitoring/toolkit/glossary.pdf and Nonprofit Good Practice Guide Glossary)
CL355959
Activity
Qualitative Evaluation
Evaluation
Qualitative Evaluation
Qualitative Evaluation
owl:Class
Anti-HIV Therapy
AIDS anti-HIV therapy
C16118
owl:Class
Antiviral Therapy
therapy, anti-HIV
Anti-HIV Therapy
Treatment of human immunodeficiency virus (HIV) infections with medications that target the virus directly, limiting the ability of infected cells to produce new HIV particles.
Anti-HIV Therapy
Anti-HIV Therapy
therapy, AIDS anti-HIV
Therapeutic or Preventive Procedure
C1510425
C53196
Random Sampling
Simple Random Sampling
Simple Random Sampling
Simple Random Sampling
Quantitative Concept
C0681878
Simple Random Sampling
owl:Class
Differentiation Therapy
Therapeutic Procedure
Differentiation Therapy
Drug therapy aimed at forcing cancer cells to resume the process of maturation and therefore to induce tumor to a more differentiated, less aggressive state. Differentiation therapy restrains cancer cells growth and facilitates the application of more conventional therapies.
C15571
therapy, differentiation
Differentiation Therapy
CL030648
owl:Class
Therapeutic or Preventive Procedure
Differentiation Therapy
Coping
Personal Behavior
Coping
Risk Reduction
C0009967
The process of successfully managing difficult or challenging situations.
Coping
owl:Class
Individual Behavior
Coping
C78176
owl:Class
C62290
Hold
Hold
Hold
Activity
Contain; have within.
Instruction Imperative
CL365033
Action
Hold
Activity
C61570
owl:Class
Action
Deregulation
Deregulation
Deregulation
CL364670
The act or process of removing restrictions and controls.
Deregulation
Deregulated
A type of Magnetic Resonance Imaging that uses only one nuclear spin excitation per image and therefore can obtain images in a fraction of a second rather than the minutes required in traditional MRI techniques. It is used in a variety of medical and scientific applications.(From MSH 2001).
Echo-Planar Imaging
Echo-Planar Imaging
Echo-Planar Imaging
C0162734
Diagnostic Procedure
Medical Imaging, Planar
owl:Class
Echo-Planar Imaging
Magnetic Resonance Imaging
C17558
CL052553
Activity
C25625
owl:Class
The act or process of making something ready; also an anatomic or pathologic specimen made ready and preserved for study.
Instruction Imperative
Action
PREP
Preparation
Preparation
Prepare
Preparation
Preparation
Deploy
Action
Deployment
Activity
C81906
Deploy
Deploy
Deploy
owl:Class
To distribute systematically or strategically.
owl:Class
Molecular Analysis
Laboratory Procedure
Serial Analysis of Gene Expression
SAGE
Serial Analysis of Gene Expression
C18480
A method of assessing the variation in the type or amount of genes expressed in different tissues, at different times in development or in normal versus malignant cells.
C0876956
Serial Analysis of Gene Expression
Serial Analysis of Gene Expression
owl:Class
C0237935
Behavior
C71753
Behavior
Trust
Trust
Confidence in or reliance on a person or thing.
Trust
Trust
Cryo-Electron Microscopy
Laboratory Procedure
Electron microscopy involving an aqueous suspension of a sample which is applied in an extremely thin film to a grid, frozen in liquid nitrogen and maintained in this state by means of a special mount. The imaging of frozen-hydrated molecules and organelles permits the best possible resolution closest to the living state, free of chemical fixatives or stains.
C18113
Cryo-Electron Microscopy
Electron Microscopy
Cryo-Electron Microscopy
C0597705
owl:Class
Cryo-Electron Microscopy
Enzyme Therapy
C71592
Enzyme Therapy
Therapeutic Procedure
Enzyme Therapy
owl:Class
C0596530
Enzyme Therapy
Therapeutic or Preventive Procedure
owl:Class
CL100748
Computerized Thermal Imaging
CTI
Thermography
Computerized Thermal Imaging
Computerized Thermal Imaging
Computerized Thermal Imaging
A non-invasive imaging method that uses a thermal sensitive camera to capture a digital image based on heat radiating from the body. In trials for detection of breast cancer, computer-assisted interpretation of the digital image helps to determine whether a local abnormality in breast tissue temperature is present, which may indicate the presence of disease.
Diagnostic Procedure
C21328
Make
owl:Class
Make
C64661
Activity
Make
let it be made
fiat
Instruction Imperative
CL370259
Make
ft.
A quantitative measurement of the amount of lipids (cholesterol, lipoproteins, and triglycerides) present in a sample.
Lipid Measurement
Lipid Measurement
C74949
owl:Class
Lipid Measurement
Laboratory Procedure
Chemistry Test
Lipid Measurement
C0523744
Swallow Evaluation
Health Care Activity
CL343831
Evaluation of Risk Factors
Swallow Evaluation
The administration of liquids in assorted thicknesses to determine the ability of a patient to swallow without aspiration. Swallow evaluation involves a variety of approaches, but may be divided into endoscopic and non-endoscopic techniques.
Swallow Evaluation
C48874
owl:Class
Swallow Evaluation
<def-source>CDISC</def-source><def-definition>A quantitative measurement of the mean amount of hemoglobin per erythrocyte in a biological specimen.</def-definition>
The mean cell hemoglobin (MCH) , which is the average amount of hemoglobin in the average red cell. The MCH is a calculated value derived from the measurement of hemoglobin and the red cell count.
Ery. Mean Corpuscular Hemoglobin
CDISC SDTM Terminology
Erythrocyte Mean Corpuscular Hemoglobin
C64797
MCH
Erythrocyte Mean Corpuscular Hemoglobin
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Laboratory Test Terminology by Code
CDISC
Hematology Test
Erythrocyte Mean Corpuscular Hemoglobin
Clinical Data Interchange Standards Consortium Terminology
Laboratory Procedure
owl:Class
C0369183
Erythrocyte Mean Corpuscular Hemoglobin
Prior Radiation Therapy
Prior Limited Radiation
CL001444
Prior Limited Radiation
Clinical Attribute
Prior Limited Radiation
Prior Limited Radiation
Cancer therapy using ionizing radiation to a limited (&lt; 50%) portion of the body.
owl:Class
C15905
Therapeutic Cold
Pain Therapy
Therapeutic or Preventive Procedure
Cold Therapy
The application of cold to appropriate painful areas to reduce inflammation immediately after an injury.
Therapeutic Cold
owl:Class
C21118
Therapeutic Cold
Therapeutic Cold
CL335290
Patient Oriented Research
A study initiated in 1994 by researchers at the National Cancer Institute (NCI) to look at the impact that treatments for primary prostate cancer have on the quality of life of patients. PCOS is the first systematic evaluation of health-related quality-of-life issues for prostate cancer patients conducted on a multiregional scale.
CL014585
Prostate Cancer Outcomes Study
Cancer Research
PCOS
Prostate Cancer Outcomes Study
owl:Class
Prostate Cancer Outcomes Study
Research Activity
Prostate Cancer Outcomes Study
C16166
owl:Class
Therapeutic or Preventive Procedure
Protein Replacement Therapy
Replacement Therapy
C16221
CL026537
Protein Replacement Therapy
Administration of a protein to compensate for the loss, as from disease or surgery, of a gland or tissue that would normally produce the protein.
Protein Replacement Therapy
Protein Replacement Therapy
Enzyme Replacement Therapy
Amputation Above-Knee
Above-Knee Amputation
Above Knee Amputation
Amputation
Surgical removal of all or part of the leg, made at any point of the femur.
Above-Knee Amputation
Therapeutic or Preventive Procedure
Above-Knee Amputation
Above-Knee Amputation
C0002691
C51772
owl:Class
owl:Class
Two-Stage Cluster Random Sampling
Quantitative Concept
CL378068
Two-Stage Cluster Random Sampling
C71500
Two-Stage Cluster Random Sampling
Cluster Random Sampling
Two-Stage Cluster Random Sampling
Laboratory Procedure
Coagulation Study
owl:Class
Coagulation Study
C0005790
Coagulation Study
Coagulation Study
Hematology Test
C62662
Combinatorial Synthesis
Technique for making and testing many complex materials in parallel: computer guided synthesis in which all possible combinations are made. Combinatorial synthesis is not random, but systematic and repetitive, using sets of chemical "building blocks" to form a diverse set of molecular entities. Initial synthesis is usually made on a solid substrate. The technique lays down the materials in a checkerboard arrangement, as thin squares arranged in a grid. Scientists use combinatorial chemistry to create large populations of molecules, or libraries, that can be screened efficiently en masse.
Activity
C19321
Combinatorial Synthesis
owl:Class
Research Activity
Combinatorial Synthesis
CL003716
Combinatorial Synthesis
Premenopausal
Premenopausal
owl:Class
premenopausal
C15491
Menopausal Status
<def-source>NCI-GLOSS</def-source><def-definition>Refers to the time before menopause. Menopause is the time of life when a women's menstrual periods stop permanently; also called "change of life."</def-definition>
CL029630
Premenopausal
Clinical Attribute
Premenopausal
CL370730
External Radiation Therapy
C66890
Therapeutic or Preventive Procedure
External Radiation Therapy
External Radiation Therapy
External Radiation Therapy
Radiation Therapy
external radiation
owl:Class
C0599946
Action
Attenuation
Activity
A weakening in force or intensity.
Attenuation
Attenuation
C61471
owl:Class
Attenuation
Exogenous Hormone Therapy
Exogenous Hormone Therapy
owl:Class
C16093
Exogenous Hormone Therapy
Endocrine Drug Therapy
Exogenous Hormone Use
CL008673
Therapeutic or Preventive Procedure
Exogenous Hormone Therapy
Isodose
Isodose
A radiation dose of equal intensity applied to more than one body area; of or relating to points or zones in a medium that receive equal doses of radiation.
Isodose
Isodose
CL360673
C54654
Conceptual Entity
Dose
owl:Class
CD8 T Cell to Lymphocyte Ratio Measurement
<def-source>CDISC</def-source><def-definition>A relative measurement (ratio or percentage) of CD8 T cells to all lymphocytes in a biological specimen.</def-definition>
CDISC SDTM Terminology
CDISC
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Name
Blood Cell Count Ratio Measurement
The determination of the ratio of CD8 T cells compared to lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
C74639
CDISC SDTM Laboratory Test Terminology by Code
CD8 T Cell to Lymphocyte Ratio Measurement
owl:Class
Laboratory Procedure
CD8LY
CD8/Lymphocytes
CD8 T Cell to Lymphocyte Ratio Measurement
CL384378
CD8 T Cell to Lymphocyte Ratio Measurement
Clinical Data Interchange Standards Consortium Terminology
C82002
Apolipoprotein E Measurement
Apolipoprotein E Measurement
Apolipoprotein E Measurement
Apolipoprotein E Measurement
Protein or Enzyme Type Measurement
The determination of the amount of apolipoprotein E present in a sample.
owl:Class
Diagnostic Procedure
C0177804
owl:Class
Bone Density Test
Bone Mineral Density Test
A scanning procedure used to measure calcium and other minerals present in bone.
Bone Mineral Density Test
Bone Mineral Density Test
C61545
Bone Mineral Density Test
Diagnostic Procedure
Bone Mineral Density
BMD
CL356381
Quantitative Concept
Unpaired t-Test
Unpaired t-Test
C53233
owl:Class
Unpaired t-Test
Unpaired t-Test
t-Test
Wide Skin Excision
Excision
CL343280
Wide Skin Excision
Surgical excision of diseased skin tissue with a border of healthy tissue surrounding the lesion. It is often used as a treatment for skin cancers. The margin of the healthy tissue may range from a few millimeters for small cancers up to around 15 mm for larger cancers.
owl:Class
Wide Skin Excision
Therapeutic or Preventive Procedure
C48608
Wide Skin Excision
CDISC
C74679
IRON
Clinical Data Interchange Standards Consortium Terminology
FE
Iron Measurement
Iron
CDISC SDTM Terminology
CDISC SEND Terminology
C0337439
The determination of the amount of iron present in a sample.
Iron Measurement
Chemistry Test
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Laboratory Test Terminology by Code
Iron Measurement
owl:Class
Iron Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the iron in a biological specimen.</def-definition>
Clinical Study by Phase
C70820
Clinical Trial
Clinical Study by Phase
owl:Class
Research Activity
Clinical Study by Phase
Clinical Study by Phase
CL375965
<def-source>CSP2000</def-source><def-definition>surgical removal of the uterus.</def-definition>
C0020699
Procedure_Has_Excised_Anatomy only Uterus
Hysterectomy
<def-source>MSH2001</def-source><def-definition>Excision of the uterus.</def-definition>
Hysterectomy
Therapeutic or Preventive Procedure
Hysterectomy
Gynecological Surgical Procedure
owl:Class
hysterectomy
C15256
A surgical procedure to remove the uterine body (partial hysterectomy) or the uterine body and cervix (total hysterectomy). -- 2004
<def-source>NCI-GLOSS</def-source><def-definition>(hiss-ter-EK-toe-mee) An operation in which the uterus is removed.</def-definition>
Hysterectomy
Blood-Brain Barrier Disruption Chemotherapy
Blood-Brain Barrier Disruption Chemotherapy
Blood-Brain Barrier Disruption Chemotherapy
owl:Class
BBBD Chemotherapy
CL004783
Treatment modality used to increase the delivery of chemotherapeutic agents and monoclonal antibodies to the central nervous system tissue through temporal disruption of the blood brain barrier.
C16026
Blood-Brain Barrier Disruption Chemotherapy
Therapeutic or Preventive Procedure
Chemotherapy
Blood Brain Barrier Disruption Chemotherapy
RMS
Quadratic Mean
C73485
A statistical measure of the magnitude of a set of variable values. The root mean square is the square root of the mean value for the squares of the original values.
owl:Class
Quantitative Concept
CL383708
Root Mean Square
Root Mean Square
Root Mean Square
Dispersion
Root Mean Square
Leukocyte Count
owl:Class
Leukocyte Count
CL353522
Leukocyte Count
WBC
CDISC SDTM Terminology
C51948
<def-source>CDISC</def-source><def-definition>A count of the leukocytes per unit of a biological specimen.</def-definition>
Laboratory Procedure
Leukocyte Count
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
White Blood Cells
Leukocytes
A test to determine the number of leukocytes in a sample of blood.
CDISC SDTM Laboratory Test Terminology by Code
Blood Cell Count
CDISC
Clinical Data Interchange Standards Consortium Terminology
Representative
Representation
Representational
Representation
C67045
An activity that stands as an equivalent of something or results in an equivalent; typical of, or the same as, others in a larger group of people or things.
CL371555
Representation
Represent
Activity
Action
owl:Class
Representation
Culturing, in vitro Vertebrate, Cell
Culturing, in vitro Vertebrate, Cell
Cell Culture
Culturing, in vitro Vertebrate, Cell
Propagation of vertebrate animal cells in culture.
C19481
CL004386
owl:Class
Culturing, in vitro Vertebrate, Cell
Laboratory Procedure
Mutation Analysis
C18302
Mutation Analysis
Molecular Analysis
Laboratory Procedure
owl:Class
A procedure to test for the presence of a specific mutation or a set of mutations as opposed to complete gene sequencing or mutation scanning, which detect most, if not all, mutations in the tested region. (From GeneTests).
Mutation Analysis
Mutation Analysis
CL032114
Long-term Follow-up
Longterm Follow-up
Longterm Follow-up
Follow-up activities that continue beyond the active intervention period.
CL004807
owl:Class
Longterm Follow-up
Follow-up
Longterm Follow-up
Health Care Activity
C16032
VATS
Therapeutic or Preventive Procedure
Video-assisted Thoracic Surgery
Video-assisted Thoracic Surgery
Video-assisted Thoracic Surgery
Video-Assisted Surgery
owl:Class
Endoscopic surgery of the pleural cavity performed with visualization via video transmission.
C63704
C0752151
Video-assisted Thoracic Surgery
Spiral CT
C20094
Low-Dose Spiral CT
Low-Dose Spiral CT
Low-Dose Spiral CT
Low-Dose Spiral CT
Diagnostic Procedure
CL016114
owl:Class
A type of computed tomography whereby a low dose of X-ray modality is used to image certain organs i.e. the lungs.
C81301
The method referring to the use of medical devices such as vacuum extractor or forceps to assist with the delivery of a fetus.
Newborn Screening
Vaginal Assisted Delivery
Therapeutic or Preventive Procedure
Vaginal Assisted Delivery
owl:Class
Vaginal Assisted Delivery
Birth Method of Delivery
Vaginal Assisted Delivery
Stage Grouping
CL322400
owl:Class
Diagnostic Procedure
Stage Grouping
Stage Grouping
Staging
Stage Grouping
C38027
An assessment based on the combined evaluation of the patient's T stage, M stage, and N stage.
owl:Class
1A4; Basic Science Research (includes vaccine and chemotherapy development), Biomedical Research
C15797
Diagnostic Methods and Reagents
Diagnostic Methods and Reagents
Diagnostic Methods and Reagents
Diagnostics Research
Diagnostic Methods and Reagents
Conceptual Entity
CL000304
Radical Lymph Node Dissection
Diagnostic Procedure
Radical Lymph Node Dissection
Lymphadenectomy
Radical Lymph Node Dissection
C0193854
C48936
Radical Lymph Node Dissection
Therapeutic or Preventive Procedure
owl:Class
Partial Blind Study
CL371550
Partial Blind
Research Activity
A study in which the subject, the investigator, or anyone assessing the outcome is aware of the assignment in at least one treatment group but unaware of the treatment assignment(s) in one or more other treatment groups.
Partial Blind Study
Partial Blind Study
Partial Blind Study
C67020
Trial Blinding Schema
owl:Class
Southern Blotting
Southern Blot Hybridization
owl:Class
C0005862
A technique for the detection of specific DNA fragments that have been separated by polyacrylamide-gel electrophoresis, transferred to a nitrocellulose or other type of paper or nylon membrane, and detected by hybridization and visualization with a labeled probe.
Southern Blotting
Southern Blotting
Southern Blot
Laboratory Procedure
C16356
Southern Blotting
Blotting, Southern
DNA Analysis
Diagnostic Procedure
C49099
BOLD
Blood Oxygen Level Dependent Imaging
Blood Oxygen Level Dependent Functional Magnetic Resonance Imaging
owl:Class
Blood Oxygen Level Dependent Imaging
Blood Oxygen Level Dependent Imaging
Functional Magnetic Resonance Imaging
A magnetic resonance imaging technique that uses the difference between the magnetic signals of hemoglobin when it is carrying oxygen (oxyhemoglobin) and when it is not carrying oxygen (deoxyhemoglobin) to detect metabolic activity, and hence neurologic activity, in the brain.
BOLD fMRI
CL343608
Blood Oxygen Level Dependent Imaging
c-Myc Staining Method
owl:Class
Special Histology Staining Method
c-Myc Staining Method
cmyc
C23035
Laboratory Procedure
Cmyc Staining Method
C1522545
MYC
c-Myc Staining Method
Cmyc Staining Method
c-Myc staining is a sensitive immunohistochemical method for studying the tissue localization of c-Myc protein using antibody followed by a microscopic observation of the c-Myc staining distribution. The technique is used to detect overexpression of c-Myc oncogene which leads to cancer.
c-Myc Staining Method
Partial Thyroidectomy
CL354144
Thyroidectomy
owl:Class
Therapeutic or Preventive Procedure
Surgery involving partial excision of the thyroid gland.
C51921
Partial Thyroidectomy
Partial Thyroidectomy
Subtotal Thyroidectomy
Procedure_Has_Partially_Excised_Anatomy only 'Thyroid Gland'
Partial Thyroidectomy
CL319708
owl:Class
Therapeutic or Preventive Procedure
Dendritic Cell Therapy
C28976
Dendritic Cell Therapy
Dendritic Cell Therapy
Biological Cancer Immunotherapy
Dendritic Cell Therapy
Serum Total Bilirubin Measurement
C61031
owl:Class
Serum Chemistry Measurement
Laboratory Procedure
C1278039
A quantitative measurement of the total amount of bilirubin present in a sample of serum.
Serum Total Bilirubin Measurement
Total Bilirubin Measurement
Serum Total Bilirubin Measurement
Serum Total Bilirubin Measurement
Organism Attribute
C82474
LAYING
owl:Class
Breeding
Egg Laying
Egg Laying
Egg Laying
Egg Laying
Laboratory Procedure
Centrifugation
CL343092
Pellet Formation
Pellet Formation
Formation by cetrifugation of a tightly packed sample in the bottom of a tube.
C45813
Pellet Formation
Pellet Formation
Pellet
owl:Class
Laboratory Procedure
Electrolyte Measurement
CDISC SDTM Laboratory Test Terminology by Name
Potassium Measurement
A quantitative measurement of the amount of potassium present in a sample.
Potassium Measurement
owl:Class
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Code
C0202194
CDISC
Potassium Measurement
Potassium Measurement
CDISC SEND Terminology
CDISC SDTM Terminology
<def-source>CDISC</def-source><def-definition>A measurement of the potassium in a biological specimen.</def-definition>
Potassium
C64853
K
owl:Class
A procedure for critical evaluation; a means of determining the presence, quality, or truth of something.
Action
CL356878
C47891
Test
Activity
Test
Test
Test
Procedures utilized to save organic substances from decay. Some preservation procedures are meant to maintain cells, tissues, or organisms in a viable state.
CL369262
C64262
Biologic Sample Preservation Procedure
Laboratory Procedure
Preservation Procedure
Biologic Sample Preservation Procedure
owl:Class
Biologic Sample Preservation Procedure
Biologic Sample Preservation Procedure
Protein or Enzyme Type Measurement
Acid Phosphatase Measurement
owl:Class
Laboratory Procedure
Acid Phosphatase Measurement
Acid Phosphatase Measurement
The determination of the amount of acid phosphatase present in a sample.
Acid Phosphatase Measurement
C80163
CDISC SEND Terminology
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
C0474535
owl:Class
Clinical Data Interchange Standards Consortium Terminology
Erythrocyte Mean Corpuscular Hemoglobin Concentration
C64798
Ery. Mean Corpuscular HGB Concentration
Erythrocyte Mean Corpuscular Hemoglobin Concentration
CDISC
Hematology Test
CDISC SDTM Laboratory Test Terminology by Name
<def-source>CDISC</def-source><def-definition>A quantitative measurement of the mean amount of hemoglobin per erythrocytes in a specified volume of a biological specimen.</def-definition>
Erythrocyte Mean Corpuscular Hemoglobin Concentration
The mean cell hemoglobin concentration (MCHC), which is the average concentration of hemoglobin in a given volume of blood. The MCHC is a calculated value derived from the measurement of hemoglobin and the hematocrit.
Erythrocyte Mean Corpuscular Hemoglobin Concentration
MCHC
Laboratory Procedure
Research Activity
Magnetic Bead Separation
Magnetic Bead Separation
Magnetic Bead Technology
CL003638
Magnetic Bead Separation
C19304
A cell-separation technique where magnetizable microspheres or beads are first coated with monoclonal antibody, allowed to search and bind to target cells, and are then selectively removed when passed through a magnetic field. Among other applications, the technique is commonly used to remove tumor cells from the marrow of patients who are to undergo autologous bone marrow transplantation.
owl:Class
Magnetic Bead Separation
Research Technique
Hormone Receptor Test
Immunodiagnostic Procedure
Diagnostic Procedure
Laboratory Procedure
Hormone Receptor Test
Hormone Receptor Test
owl:Class
CL032282
<def-source>NCI-GLOSS</def-source><def-definition>A test to measure the amount of certain proteins, called hormone receptors, in cancer tissue. Hormones can attach to these proteins. A high level of hormone receptors may mean that hormones help the cancer grow.</def-definition>
C18313
hormone receptor test
A hormone receptor test measures the amount of certain hormone receptors proteins in cancer tissue. Hormones (such as estrogen and progesterone that naturally occur in the body) can attach to these proteins. If the test is positive, it indicates that the hormone is probably helping the cancer cells grow.
Hormone Receptor Test
Numeric Conversion
owl:Class
Phenomenon or Process
The process by which a value is assigned to represent another set of values for ease of evaluation within a particular process.
Numeric Conversion
Numeric Conversion
Numeric Conversion
CL384039
Calculation
C74552
Nicotine Nasal Spray
Nicotine Replacement
owl:Class
Nicotine Nasal Spray
A method for nicotine replacement.
Therapeutic or Preventive Procedure
C1249285
Nicotine Nasal Spray
Nicotine Nasal Spray
C16162
Nutritional Intervention
owl:Class
Nutritional Supplementation
C51983
Nutritional Supplementation
Nutritional Supplementation
Therapeutic or Preventive Procedure
Nutritional Supplementation
CL354747
Gene Targeting
A technique that involves integration of an exogenous DNA sequence encoding a specific gene into the genome of an organism by homologous recombination.
Gene Targeting
Molecular Biology Research Technique
Gene Targeting
owl:Class
Gene Targeting
C0242613
C17742
Molecular Genetic Technique
Continuous Distribution
Weibull Distribution
Quantitative Concept
C53226
Weibull Distribution
CL356586
owl:Class
Weibull Distribution
Weibull Distribution
CDISC SDTM Terminology
CDISC
owl:Class
CDISC SDTM Laboratory Test Terminology by Name
C0201836
A quantitative measurement of alanine aminotransferase present in a sample.
ALT
SGPT
Alanine Aminotransferase Measurement
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
CDISC SEND Terminology
Alanine Aminotransferase
Alanine Aminotransferase Measurement
Liver Function Test
Laboratory Procedure
C64433
Alanine Aminotransferase Measurement
Alanine Aminotransferase Measurement
Protein or Enzyme Type Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the alanine aminotransferase in a biological specimen.</def-definition>
A novel karyotyping procedure which is based on the simultaneous hybridization of 24 chromosome-specific painting probes labeled with different fluorochromes or fluorochrome combinations. The measurement of defined emission spectra by means of interferometer-based spectral imaging allows for the definitive discernment of all human chromosomes in different colors. (from Schrock et al., Hum Genet 1997:101:255-62)
Molecular Biology Research Technique
Spectral Karyotyping
Chromosome Painting
Laboratory Procedure
Color Karyotyping
C20068
Spectral Karyotyping
Spectral Karyotyping
owl:Class
Spectral Karyotype
CL015647
Spectral Karyotyping
Dental Protraction
owl:Class
C82128
Dental Protraction
Protraction
Therapeutic or Preventive Procedure
Dental Protraction
Dental Protraction
Anterior displacement of the teeth and/or bones of the face.
Orthodontic Treatment
Population Study
Research Activity
C0681876
Multidisciplinary study done at the population level or among the population groups, generally to find the cause, incidence or spread of the disease or to see the response to the treatment, nutrition or environment.
C15716
owl:Class
Population Study
Population Study
Research Activity
Population Study
Clinical Testing
Clinical Testing
Clinical Testing
CL000227
Testing
Health Care Activity
Small-scale testing (usually on SBIRs) of new technology in a small group of patients or normal volunteers. Does not meet the rigorous criteria of a clinical trial.
Clinical Testing
C15791
Clinical Evaluation
owl:Class
CL384772
Clinical Data Interchange Standards Consortium Terminology
Crystal Growth Measurement
The determination of the amount of cystine crystals present in a sample.
Cystine Crystal Measurement
CYCYSTIN
Laboratory Procedure
Cystine Crystals
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Name
owl:Class
CDISC
C74674
<def-source>CDISC</def-source><def-definition>A measurement of the cystine crystals present in a biological specimen.</def-definition>
CDISC SDTM Laboratory Test Terminology by Code
Cystine Crystal Measurement
CDISC SDTM Terminology
Cystine Crystal Measurement
Cystine Crystal Measurement
Quantitative Concept
Geographic Area Level Statistic
Statistical Technique
Geographic Area Level Statistic
Geographic Area Level Statistic
C53185
Geographic Area Level Statistic
CL356273
owl:Class
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Laboratory Test Terminology by Name
Promonocyte Count
CL384339
<def-source>CDISC</def-source><def-definition>A measurement of the promonocytes per unit of a biological specimen.</def-definition>
owl:Class
C74621
Promonocytes
CDISC
Promonocyte Count
Promonocyte Count
The determination of the number of promonocytes in a blood sample.
Clinical Data Interchange Standards Consortium Terminology
CDISC SEND Terminology
Leukocyte Count
PROMONO
Promonocyte Count
CDISC SDTM Terminology
Laboratory Procedure
Action
Report Nullification
Action(s) undertaken to indicate that a previously transmitted report should be considered completely void (nullified).
Activity
Report Nullification
owl:Class
NULLIFICATION
C68625
CL371957
Report Nullification
Report Nullification
Quantitative Concept
C53188
Census Tract Level Statistic
Census Tract Level Statistic
owl:Class
CL356251
Census Tract Level Statistic
Geographic Area Level Statistic
Census Tract Level Statistic
NMRI
owl:Class
Nuclear Magnetic Resonance Imaging
Magnetic Resonance Imaging
Diagnostic Imaging
Imaging that uses radiofrequency waves and a strong magnetic field rather than x-rays to provide amazingly clear and detailed pictures of internal organs and tissues. The technique is valuable for the diagnosis of many pathologic conditions, including cancer, heart and vascular disease, stroke, and joint and musculoskeletal disorders.
<def-source>NCI-GLOSS</def-source><def-definition>(mag-NET-ik REZ-o-nans IM-a-jing) MRI. A procedure in which a magnet linked to a computer is used to create detailed pictures of areas inside the body. Also called nuclear magnetic resonance imaging.</def-definition>
C16809
nuclear magnetic resonance imaging
Magnetic Resonance Imaging Scan
Diagnostic Procedure
C0024485
magnetic resonance imaging
NMR Imaging
Magnetic Resonance Imaging
MRI
Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance
Magnetic Resonance Imaging
Magnetic Resonance Imaging
An operation to create an opening from inside the body to the outside, making a new way to pass urine.
CL032832
owl:Class
Ostomy
Urostomy
urostomy
Urostomy
C15759
Therapeutic or Preventive Procedure
<def-source>NCI-GLOSS</def-source><def-definition>(yoo-RAHS-toe-mee) An operation to create an opening from inside the body to the outside, making a new way to pass urine.</def-definition>
Urologic Surgical Procedure
Urostomy
Urostomy
C17644
<def-source>NCI-GLOSS</def-source><def-definition>A procedure used to examine the vagina, uterus, fallopian tubes, and bladder. An instrument is inserted into the vagina, and sound waves bounce off organs inside the pelvic area. These sound waves create echoes, which a computer uses to create a picture called a sonogram.</def-definition>
TVS
Transvaginal Ultrasound
owl:Class
Transvaginal Ultrasound
transvaginal ultrasound
Transvaginal Ultrasound
C0203418
Transvaginal Ultrasound
TVU
Diagnostic Procedure
A technique in which sound waves are sent out by an ultrasound probe that has been inserted in the vagina and a computer uses the ultrasound echoes to create an image of the female genital tract. The test can be performed to evaluate women with infertility problems, abnormal bleeding, sources of unexplained pain, congenital malformations of the uterus and ovaries, and possible tumors and infection.
Ultrasound Imaging
Diagnostic Procedure
Cognitive Assessment
Cognitive Assessment
C62736
owl:Class
Cognitive Assessment
CL034372
Cognitive Assessment
Medical Examination
Left Hemihepatectomy
CL353511
Surgical removal of the left hemisphere of the liver.
C51571
owl:Class
Left Hemihepatectomy
Procedure_Has_Completely_Excised_Anatomy only 'Left Lobe of the Liver'
Left Hemihepatectomy
Left Hemihepatectomy
Therapeutic or Preventive Procedure
Partial Hepatectomy
Radionuclide Ventriculogram Scan
CL322424
Multi-Gated Acquisition Scan
owl:Class
Radionuclide Imaging
A multi-gated acquisition (MUGA) scan and a form of radionuclide imaging that provides a comprehensive look at blood flow and the function of the lower chambers of the heart ventricles.
Radionuclide Ventriculogram Scan
Radionuclide Ventriculogram Scan
MUGA
Diagnostic Procedure
C38073
Radionuclide Ventriculogram Scan
Urine Chemistry Measurement
C61044
Urinalysis
CL364262
A quantitative measurement of a particular substance present in a sample of urine.
owl:Class
Urine Chemistry Measurement
Urine Chemistry Measurement
Urine Chemistry Measurement
Laboratory Procedure
MYCN Messenger RNA Expression Measurement
MYCN Messenger RNA Expression Measurement
C79098
MYCN Messenger RNA Expression Measurement
MYCN Messenger RNA Expression Measurement
CL387626
owl:Class
RNA Analysis
Laboratory Procedure
Research Activity
Cancer Surveillance Research
owl:Class
Cancer Surveillance Research
CL007285
Cancer Surveillance Research
Cancer Research
Cancer Surveillance Research
C16053
Epidemiology Research
Retire
Withdraw
Withdraw
Withdraw
C38061
To cease active participation in; remove from active use.
CL387771
Retired
Functional Concept
Withdrawn
Withdrawal
owl:Class
Action
Withdraw
Light Scattering
Laboratory Procedure
Static Light Scattering
Static Light Scattering
Classical Light Scattering
The average scattering intensity as a function of both the angle and concentration of particles in dilute solutions.
C62325
owl:Class
Rayleigh Light Scattering
CL364965
Static Light Scattering
Static Light Scattering
Distance Learning
Educational Activity
Refers to the process by which students and teachers at different sites carry out learning and instruction via cable connection, conventional phone lines, or computer networks.
Distance Learning
Distance Learning
Distance Learning
C18157
C0600563
Educational Activity
owl:Class
C0454077
C15650
Electron Beam Therapy
Radiation therapy using electron beam
External Beam Radiation Therapy
Radiation Ionizing Radiotherapy
Electron Beam Therapy
owl:Class
Therapeutic or Preventive Procedure
Electron Beam Therapy
Electron Beam Therapy
owl:Class
CNS Affecting Drug Measurement
Hallucinogen Measurement
Hallucinogen Measurement
Hallucinogen Measurement
Laboratory Procedure
Hallucinogen Measurement
C75343
The determination of the amount of any hallucinogen present in a sample.
CL384639
C0031327
<def-source>NCI-GLOSS</def-source><def-definition>The activity of drugs in the body over a period of time, including the processes by which drugs are absorbed, distributed in the body, localized in the tissues, and excreted.</def-definition>
Research Activity
Pharmacokinetics
pharmacokinetics
Pharmacokinetics
PK
C15299
Pharmacokinetics
The characteristic movements of drugs within biological systems, as affected by absorption, distribution, binding, elimination, biotransformation, and excretion; particularly the rates of such movements.
owl:Class
Drug Development
Pharmacokinetics
CL323506
Research Activity
Field Survey
Field Survey
A descriptive or analytic study of risk factors or disease determinants in populations. Most epidemiologic and some genetic studies fit within this category.
C39404
owl:Class
Field Survey
Population Study
Field Survey
Wedge Excision
Wedge Excision
owl:Class
Wedge Excision
Therapeutic or Preventive Procedure
Excision
Wedge Excision
C51690
Wedge Resection
CL355603
Diazepam Measurement
Diazepam Measurement
owl:Class
C75372
Laboratory Procedure
Diazepam Measurement
C0202368
Benzodiazepine Measurement
The determination of the amount of diazepam present in a sample.
Diazepam Measurement
Renography
Radiography
Renography
Renography
C38086
Diagnostic Procedure
owl:Class
Renography
A nuclear imaging method that evaluates bilateral renal function including glomerular filtration, renal excretion and renal tubular cell uptake markers by using radionuclides.
C0205917
Plasmacytoid Lymphocyte to Lymphocyte Ratio Measurement
CDISC SDTM Laboratory Test Terminology by Code
<def-source>CDISC</def-source><def-definition>A relative measurement (ratio or percentage) of the plasmacytoid lymphocytes (lymphocytes with peripherally clumped chromatin and often deep blue cytoplasm, and that appear similar to plasma cells) to all lymphocytes in a biological specimen.</def-definition>
owl:Class
C74648
Clinical Data Interchange Standards Consortium Terminology
CL384422
The determination of the ratio of plasmacytoid lymphocytes compared to all lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
LYMPLLY
Plasmacytoid Lymphocyte to Lymphocyte Ratio Measurement
Plasmacytoid Lymphocyte to Lymphocyte Ratio Measurement
Plasmacytoid Lymphocytes/Lymphocytes
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
Laboratory Procedure
Plasmacytoid Lymphocyte to Lymphocyte Ratio Measurement
CDISC
Blood Cell Count Ratio Measurement
CL384322
Lactate Dehydrogenase Isoenzyme 2 Measurement
Protein or Enzyme Type Measurement
Lactate Dehydrogenase Isoenzyme 2 Measurement
<def-definition>A measurement of the lactate dehydrogenase isoenzyme 2 in a biological specimen.</def-definition><def-source>CDISC</def-source>
owl:Class
CDISC SEND Terminology
CDISC SDTM Terminology
Lactate Dehydrogenase Isoenzyme 2 Measurement
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Code
LDH2
C74888
Laboratory Procedure
The determination of the lactate dehydrogenase isoenzyme 2 present in a sample.
CDISC SDTM Laboratory Test Terminology by Name
LDH Isoenzyme 2
Lactate Dehydrogenase Isoenzyme 2 Measurement
Infusion Procedure
Therapeutic or Preventive Procedure
Infusion
Therapeutic Procedure
owl:Class
infusion
<def-source>NCI-GLOSS</def-source><def-definition>A method of putting fluids, including drugs, into the bloodstream. Also called intravenous infusion.</def-definition>
Infusion Procedure
C0574032
Infusion Procedure
C15388
Infusion Procedure
owl:Class
Electron Microprobe Analysis
C78873
Research Activity
Electron Microprobe Analysis
A technique that quantifies the x-rays emitted after ionization by a finely focused beam of electrons directed onto a flat polished specimen.
CL387706
Physical Chemical Technique
Laboratory Procedure
Electron Microprobe Analysis
EMPA
Electron Microprobe Analysis
C0010399
The shedding of tears associated with emotions, usually sadness but also joy or frustration.
Activity
Cry
Crying
Crying
C77963
Behavior
Crying
Crying
owl:Class
<def-source>NCI-GLOSS</def-source><def-definition>An imaging procedure in which antibodies labeled with radioactive substances are given to the person. A picture is taken of sites in the body where the antibody localizes.</def-definition>
Immunoscintigraphy
Radioimmunodetection
C17436
Immunoscintigraphy
An imaging procedure in which antibodies labeled with radioactive substances are injected into the patient. Images are obtained by a scintillation camera.
Immunoscintigraphy
immunoscintigraphy
Diagnostic Procedure
Radionuclide Imaging
C0085264
Immunoscintigraphy
owl:Class
Promyelocytes
CDISC SDTM Terminology
Promyelocyte Count
CDISC SEND Terminology
Leukocyte Count
C74622
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Code
C0455279
<def-source>CDISC</def-source><def-definition>A measurement of the promyelocytes (immature myelocytes) in a biological specimen.</def-definition>
Promyelocyte Count
CDISC SDTM Laboratory Test Terminology by Name
Promyelocyte Count
The determination of the number of promyelocytes present in a sample.
owl:Class
PROMY
Promyelocyte Count
Laboratory Procedure
CDISC
A dose at which an infectious organism can reproduce in the host or the system in which it has been inoculated and to produce measurable effect(s). This effect may not be limited to the display of symptoms, but may also include postconvalescence antibody titers, morphologic changes, development of cellular immunity, and presence of nucleic acid incorporation.
Infectious Dose
Infectious Dose
Conceptual Entity
Infectious Dose
CL371661
Infective Dose
Infection Dose
Dose
Infectious Dose
owl:Class
C67448
Therapeutic or Preventive Procedure
C0029340
Orthomolecular Therapy
Orthomolecular Therapy
Orthomolecular Therapy
Orthomolecular Therapy
Biologically Based Practices
owl:Class
C67024
C54069
CL357185
owl:Class
Take Place
Come to pass.
Occur
Happen
Occur
Happened
Conceptual Entity
Action
Took Place
Occurred
Occur
Occur
CDISC SDTM Laboratory Test Terminology by Name
C74765
Coarse Granular Cast Measurement
Coarse Granular Cast Measurement
Coarse Granular Cast Measurement
CDISC SDTM Terminology
CDISC SEND Terminology
owl:Class
Laboratory Procedure
CDISC
CSGRANC
<def-source>CDISC</def-source><def-definition>A measurement of the coarse granular casts present in a urine specimen.</def-definition>
Coarse Granular Cast Measurement
Urine Sediment Analysis Measurement
The determination of the amount of coarse granular casts present in a urine sample.
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
CL384756
Granular Coarse Casts
Baseline Removal Method
Pseudo Mean Baseline Removal Method
Pseudo Mean Baseline Removal Method
Pseudo Mean Baseline Removal Method
Pseudo Mean Baseline Removal Method
Activity
owl:Class
CL369338
Method for identifying invariant set normalization baseline using psuedo mean expression values. Defined in the documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html.
C64242
Action Taken with Study Treatment
Treatment Regimen
Action Taken with Study Treatment
Activity
C49499
CDISC Observation Class Terminology
owl:Class
Action Taken with Study Treatment
CL356217
The reason that changes were made to the specific therapy under study.
Action Taken with Study Treatment
ACN
Fixation
C25219
owl:Class
The chemical preservation of a substance to maintain structural and/or molecular features of that substance as they exist in the living entity.
Fixed
CL337400
Fixation
Laboratory Procedure
Fixation
Fixation
Tissue Processing Technique
Macrocyte Count
CDISC SDTM Terminology
Macrocyte Count
Laboratory Procedure
The determination of the number of macrocytes in a blood sample.
Macrocyte Count
CDISC SDTM Laboratory Test Terminology by Name
Clinical Data Interchange Standards Consortium Terminology
Erythrocyte Count
CDISC
MACROCY
CL370236
<def-definition>A measurement of the macrocytes per unit of a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SEND Terminology
Macrocyte Count
Macrocytes
owl:Class
C64821
CDISC SDTM Laboratory Test Terminology by Code
C62311
Nanoparticle-Mediated Drug Delivery
Activity
CL364922
Nanoparticle-Mediated Drug Delivery
Nano Drug Delivery
Nanoparticle-Mediated Drug Delivery
owl:Class
Nanoparticle Mediated Drug Delivery
This method entails the attachment of a drug to the surface of nanoparticles. The role of the nanoparticle is to facilitate delivery of the drug to a cellular target that it would not reach in its free form.
Nanoparticle-Mediated Drug Delivery
Clinical Nanoparticle Application
C16144
Combination Drug Therapy
Combination Drug Therapy
Therapeutic Procedure
owl:Class
Therapeutic or Preventive Procedure
Drug therapy with two or more drugs given separately or together for a combined effect.
Drug Therapy, Combination
C0013218
Combination Drug Therapy
Combination Drug Therapy
CL370476
Blood Cell Count Ratio Measurement
Laboratory Procedure
<def-definition>A relative measurement (ratio or percentage) of the monocytes to leukocytes in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SEND Terminology
Clinical Data Interchange Standards Consortium Terminology
CDISC
owl:Class
MONOLE
Monocyte to Leukocyte Ratio
Monocyte to Leukocyte Ratio
CDISC SDTM Laboratory Test Terminology by Name
Monocytes/Leukocytes
CDISC SDTM Laboratory Test Terminology by Code
C64824
Monocyte to Leukocyte Ratio
Monocyte to Leukocyte Ratio
CDISC SDTM Terminology
The determination of the ratio of monocytes compared to leukocytes in a blood sample. The measurement may be expressed as a ratio or percentage.
RNA Analysis
Differential Display
Differential Display
C18483
Variation of the polymerase chain reaction used to identify differentially expressed genes. mRNA from two different tissue samples is reverse transcribed, then amplified using short, intentionally nonspecific primers. The array of bands obtained from a series of such amplifications is run on a high resolution gel, and the array of bands compared with analogous arrays from different samples. Any bands unique to single samples are considered to be differentially expressed; they can be purified from the gel, and sequenced and used to clone the full-length cDNA. Similar in result to subtractive hybridization. (DCB-CB)
Differential Display
Differential Display
owl:Class
C0887824
Laboratory Procedure
Differential Display of mRNA
<def-source>MSH2001</def-source><def-definition>Analysis of differentially expressed RNA transcripts from different tissues, cells, strains, or conditions.</def-definition>
Cancer Immunotherapy
C15438
Cancer Immunotherapy
Cancer Immunotherapy
Cancer Immunotherapy
Use of techniques, biologically active substances, and procedures to enhance or restore the ability of the host immune system to fight cancer. Also used to lessen adverse effects that may be caused by some cancer treatments.
immunotherapy for cancer
Therapeutic or Preventive Procedure
Immunotherapy
Chemotherapy
Immunotherapy, Cancer, General
owl:Class
C0278348
Immuno-Chemotherapy
Diagnostic Procedure
A way of measuring performance of left ventricle. It measures and ratios the change in the diameter of the left ventricle between the contracted and relaxed states: the difference between LV end-diastolic diameter and LV end-systolic diameter over LV end-diastolic diameter.
Shortening Fraction
Shortening Fraction
Shortening Fraction
CL322398
Shortening Fraction
Diagnostic Procedure
C38020
owl:Class
Therapeutic or Preventive Procedure
C71322
Assessment of Therapy Complications
Assessment of Therapy Complications
owl:Class
Assessment of Therapy Complications
Supportive Care
Assessment of Therapy Complications
CL377529
owl:Class
CA-125 Measurement
C0201549
CA-125 Measurement
CA-125 Measurement
Laboratory Procedure
C79089
Immunology Test
CA-125 Measurement
Neurosurgical Procedures
Neurosurgical Procedure
owl:Class
Neurosurgery
<def-source>MSH2001</def-source><def-definition>Surgery performed on the nervous system or its parts.</def-definition>
Surgery, Neurological
C15656
Procedure_Has_Target_Anatomy only 'Nervous System'
Neurological Surgery
Therapeutic or Preventive Procedure
Surgical Procedure by Site or System
Neurosurgical Procedure
Neurosurgical Procedure
C0524850
<def-source>CSP2000</def-source><def-definition>see NTs for specifics.</def-definition>
Neurosurgical Procedure
Biomedical Occupation or Discipline
An area of medicine that seeks to identify and treat medical disorders in humans that result from improper or inadequate diet, or from diseases that make the body unable to handle the nutrients delivered to it in the normal diet. The usual treatment is dietary, but can be the delivery of nutrients by other means. (from University of Pittsburgh Medical Center glossary)
owl:Class
C15784
Clinical Nutrition
CL000223
Clinical Nutrition
Nutritional Study
Health Care Activity
Clinical Nutrition
Clinical Nutrition
Prevent Transmission of HIV/Safety Blood Supply
Prevent Transmission of HIV/Safety Blood Supply
Prevent Transmission of HIV/Safety Blood Supply
Develop and assess multiple and concurrent ethical intervention strategies to reduce or prevent HIV transmission in both domestic and international settings.
CL000747
owl:Class
Prevent Transmission of HIV/Safety Blood Supply
C15838
Therapeutic or Preventive Procedure
Preventive Intervention
C53332
Consistent Estimation
Statistical Estimation
owl:Class
Consistent Estimation
CL356424
Consistent Estimation
Consistent Estimation
Research Activity
Clinical Attribute
C15512
Prior Endocrine Therapy for Advanced Disease
Prior Endocrine Therapy for Advanced Disease
CL029906
Prior Endocrine Therapy for Advanced Disease
Prior Endocrine Therapy for Advanced Disease
owl:Class
Prior Hormone Therapy
Travel
The act of going from one place to another.
C53462
owl:Class
Action
Travel
C0040802
Travel
Activity
Travel
owl:Class
Beta-2 Microglobulin Measurement
Beta-2 Microglobulin Measurement
C81980
The determination of the amount of beta-2 microglobulin present in a sample.
Immunology Test
Beta-2 Microglobulin Measurement
Beta-2 Microglobulin Measurement
Laboratory Procedure
Serum Potassium Measurement
Serum Potassium Measurement
Serum Potassium Measurement
Serum Potassium Measurement
A quantitative measurement of the amount of potassium present in a sample of serum.
Potassium Measurement
Serum Chemistry Measurement
C61030
C0302353
owl:Class
Laboratory Procedure
The determination of the amount of mu glutathione-s-transferase present in a sample.
Mu Glutathione-S-Transferase Measurement
owl:Class
Clinical Data Interchange Standards Consortium Terminology
C79457
Mu Glutathione-S-Transferase
Mu Glutathione-S-Transferase Measurement
Mu Glutathione-S-Transferase Measurement
Mu Glutathione-S-Transferase Measurement
CDISC SDTM Laboratory Test Terminology by Code
<def-definition>A measurement of the mu form of glutathione S-transferase in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Laboratory Test Terminology by Name
Protein or Enzyme Type Measurement
CDISC SDTM Terminology
GSTMU
CDISC SEND Terminology
CDISC SEND Terminology
The determination of the ratio of gamma glutamyl transferase compared to creatinine present in a sample. The measurement may be expressed as a ratio or percentage.
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
<def-definition>A relative measurement (ratio or percentage) of the gamma glutamyl transferase to creatinine in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Laboratory Test Terminology by Code
Gamma Glutamyl Transferase to Creatinine Ratio Measurement
GGTCREAT
C79446
owl:Class
Clinical Data Interchange Standards Consortium Terminology
Urine Protein Measurement
Gamma Glutamyl Transferase to Creatinine Ratio Measurement
Gamma Glutamyl Transferase to Creatinine Ratio Measurement
CDISC SDTM Terminology
Gamma Glutamyl Transferase/Creatinine
Gamma Glutamyl Transferase to Creatinine Ratio Measurement
Health Care Activity
C16154
A specific stage of progression through a sequential treatment protocol.
Treatment Step
Treatment Step
Treatment Step
Step
owl:Class
CL347305
Clinical Trials Design
Treatment Step
Imaging Technique
Diagnostic Procedure
Any technology or method that aids in the visualization of any biological process, cell, tissue or organ for use in screening, diagnosis, surgical procedures or therapy.
Imaging
Imaging Technique
owl:Class
Imaging Technique
C17369
Imaging Technique
Diagnostic Imaging Technique
Diagnostic Procedure
imaging
<def-source>NCI-GLOSS</def-source><def-definition>Methods of producing pictures of areas inside the body.</def-definition>
Medical Imaging
<def-source>NCI-GLOSS</def-source><def-definition>Tests that produce pictures of areas inside the body.</def-definition>
C0079595
imaging procedures
Imaging Procedures
Laser Capture Microdissection
Laser Capture Microdissection
Laboratory Procedure
Laser Capture Microdissection
CL003289
owl:Class
C19263
Laser capture microdissection is a new technology developed in the Intramural Program to allow sampling of specific cells under direct microscopic visualization by a pathologist. A film is placed against the heterogeneous tissue and activated by a laser beam to capture only the cells of interest. Those cells are transferred to the film to provide a visual microscopic record of what was transferred, which can be analyzed for DNA, RNA, or protein. The film upon which the cells are transferred is incorporated into the cap of a vial so that, when the transfer is done under a routine microscopic visualization, the microdissected material can immediately be put into a vial for processing. The system is integrated into a pathologist's microscope so that the cells are microdissected, transferred to the cap, and then rotated into a vial by a rotating arm in a hands-off operation. (from Cancer Genome Anatomy Project (CGAP) Update)
Microdissection
Laser Capture Microdissection
Header_Concept
CL355527
Surgical Procedure
Surgical Procedure by Site or System
Surgical Procedure by Site or System
Surgical Procedure by Site or System
C49163
owl:Class
Classification
Surgical Procedure by Site or System
CDISC SEND Terminology
The determination of the amount of cortisol present in a sample.
owl:Class
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Terminology
Cortisol
Cortisol Measurement
C0201968
Cortisol Measurement
Clinical Data Interchange Standards Consortium Terminology
Hormone Measurement
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
Cortisol Measurement
CORTISOL
C74781
Cortisol Measurement
CDISC
<def-source>CDISC</def-source><def-definition>A measurement of the cortisol in a biological specimen.</def-definition>
Laboratory Procedure
C74773
The determination of the number of squamous epithelial cells present in a urine sample.
CDISC SEND Terminology
Epithelial Cell Count
CDISC SDTM Terminology
EPISQCE
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Laboratory Test Terminology by Name
Squamous Epithelial Cell Count
owl:Class
Clinical Data Interchange Standards Consortium Terminology
Squamous Epithelial Cell Count
Squamous Epithelial Cells
Urine Sediment Analysis Measurement
CDISC
CL384351
<def-source>CDISC</def-source><def-definition>A measurement of the squamous epithelial cells present in a urine specimen.</def-definition>
Squamous Epithelial Cell Count
Squamous Epithelial Cell Count
Research Activity
Absorption, Distribution, Metabolism, and Excretion Study
Pharmacokinetics
ADME Study
ADME Study
ADME Study
C15967
A group of pharmacokinetic parameters commonly investigated during preclinical drug development.
owl:Class
CL003680
ADME Study
Calculation
C54125
Instruction Imperative
Calculation
C1441506
Activity
Calculation
Calculation
owl:Class
Calculate
Action
Calculated
The procedure or activity of determining something by mathematical or logical methods.
owl:Class
Autologous Rescue
Autologous Stem Cell Rescue
Autologous Stem Cell Rescue
Autologous Stem Cell Rescue
Autologous Stem Cell Rescue
A type of autologous hematopoietic stem cell transplantation designed to promote recovery if a prior hematopoietic stem cell transplantation fails or is not adequate.
Autologous Hematopoietic Stem Cell Transplantation
C82054
Therapeutic or Preventive Procedure
Inject
Inject
C64978
owl:Class
Inject
CL370438
Activity
Instruction Imperative
Inject
C1516879
Health Care Activity
Administrative Activity
Enrollment
Enrollment
The act of registration, entering in a list, catalog, group, study; also, the number of subjects enrolled.
owl:Class
C37948
Enrollment
Enrollment
Toxicity Attenuation
Chemoprotection
Toxicity Attenuation
C16051
Toxicity Attenuation
owl:Class
Toxicity Attenuation
CL007138
Therapeutic or Preventive Procedure
Anesthesia Procedure
Regional Anesthesia Procedure
Regional Anesthesia
Therapeutic or Preventive Procedure
owl:Class
Regional Anesthesia Procedure
C64381
C0002911
Regional Anesthesia Procedure
Regional Anesthesia Procedure
Pharmacogenomic Test
Molecular Analysis
<def-source>FDA</def-source><def-definition>An assay intended to study interindividual variations in whole-genome or candidate gene, single-nucleotide polymorphism (SNP) maps, haplotype markers, or alterations in gene expression or inactivation that may be correlated with pharmacological function and therapeutic response. In some cases, the pattern or profile of change is the relevant biomarker, rather than changes in individual markers.</def-definition>
Pharmacogenomic Test
owl:Class
Pharmacogenomic Test
C68762
Pharmacogenomic Test
CL374484
Laboratory Procedure
Starve
To deprive an organism of food or nutrients.
owl:Class
Starve
CL374497
Activity
C68782
Starve
Starve
Action
Exploratory Laparotomy
C51779
Surgical examination of the contents of the abdominal cavity as a means of diagnosis.
Exploratory Laparotomy
CL353909
Laparotomy
Therapeutic or Preventive Procedure
Exploratory Laparotomy
Exploratory Laparotomy
owl:Class
C15694
phase II/III trial
Trial Phase 2/3
Clinical Study by Phase
Phase II/III Trial
Clinical Data Interchange Standards Consortium Terminology
CDISC
CDISC SDTM Trial Phase Terminology
<def-source>CDISC</def-source><def-definition>A class of clinical study that combines elements characteristic of traditional Phase II and Phase III trials.</def-definition>
Phase II/III Trial
owl:Class
2-3
Phase II/III Trial
Research Activity
A type of clinical study that combines elements characteristic of traditional Phase II and Phase III trials.
<def-source>NCI-GLOSS</def-source><def-definition>A trial to study response to a new treatment and the effectiveness of the treatment compared with the standard treatment regimen.</def-definition>
CL031848
CDISC SDTM Terminology
Phase II/III Trial
Trial Phase 2-3
C0202458
CDISC SEND Terminology
Propoxyphene Measurement
Opioid Measurement
Propoxyphene
CDISC SDTM Terminology
The determination of the amount of propoxyphene present in a sample.
Propoxyphene Measurement
PROPOX
CDISC SDTM Laboratory Test Terminology by Code
Laboratory Procedure
owl:Class
Propoxyphene Measurement
<def-definition>A measurement of the propoxyphene present in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Laboratory Test Terminology by Name
Propoxyphene Measurement
C74885
Clinical Data Interchange Standards Consortium Terminology
owl:Class
Needle Biopsy of Prostate
Biopsy of Prostate
CL354731
Needle Biopsy of Prostate
Diagnostic Procedure
C51694
Needle Biopsy of Prostate
Removal of tissue from the prostate for microscopic examination, using a needle.
Needle Biopsy of Prostate
Needle Biopsy
Dental Retraction
owl:Class
C82126
Therapeutic or Preventive Procedure
Dental Retraction
A posterior movement of teeth.
Orthodontic Treatment
Dental Retraction
Retraction
Dental Retraction
Cooking of meats over an open flame. A cooking practice associated with increased risk of breast cancer.
owl:Class
CL014433
C20026
Flame-Broiling
Flame-Broiling
Flame-Broiling
Cooking Practices
Human-caused Phenomenon or Process
Flame-Broiling
National Cancer Institute Cancer Imaging Program
Cancer Imaging Program
owl:Class
Cancer Imaging Program
CL343514
Cancer Imaging Program
CIP
Research Activity
Cancer Imaging Program
Cancer Research
The mission of the Cancer Imaging Program, National Cancer Institute, is to promote and support Cancer-related basic, translational and clinical research in imaging sciences and technology, and integration and application of these imaging discoveries and developments to the understanding of cancer biology and to the clinical management of cancer and cancer risk.
C49047
Research Activity
CL347278
Computational Technique
Computer Modeling
C16461
Mathematical Models and Simulations
Activity
Computer Modeling
Computer Modeling
simulation
Computer Modeling
owl:Class
A technique which attempts to provide an abstract model of a particular system. It utilizes a mathematical model, which attempts to predict the behavior of the system from a set of parameters and initial conditions.
<def-source>NCI-GLOSS</def-source><def-definition>In cancer treatment, a process used to plan radiation therapy so that the target area is precisely located and marked.</def-definition>
Simulation
Gastrointestinal Complications Management
Gastrointestinal Complications Management
C62740
Supportive Care
owl:Class
Gastrointestinal Complications Management
Gastrointestinal Complications Management
CL365349
Therapeutic or Preventive Procedure
owl:Class
Caries Removal
Caries Removal
Therapeutic or Preventive Procedure
C52571
Caries Removal
Dental Procedure
Caries Removal
CL356249
Any process by which decayed tooth material is removed from the tooth.
Releasing Factor Antagonist Therapy
Therapeutic or Preventive Procedure
CL365809
owl:Class
Releasing Hormone Antagonist Therapy
C62718
Releasing Hormone Antagonist Therapy
Endocrine Drug Therapy
Releasing Hormone Antagonist Therapy
Releasing Hormone Antagonist Therapy
Household Activity
Physical Activity
Household Activity
Those physical activities which are required for our daily existence. These include personal maintenance activities such as dressing and bathing and activities for maintenance of our living space such as cleaning.
Daily Activity
Household Activity
Daily or Recreational Activity
C53291
CL356285
Household Activity
owl:Class
C51672
Procedure_May_Have_Completely_Excised_Anatomy some 'Left Lung'
Procedure_May_Have_Completely_Excised_Anatomy some 'Right Lung'
Single Lung Transplantation
Single Lung Transplantation
Single Lung Transplantation
owl:Class
Lung Transplantation
CL353675
Single Lung Transplantation
Therapeutic or Preventive Procedure
Vibration Response Imaging
Diagnostic Imaging
Vibration Response Imaging
CL375920
owl:Class
Vibration Response Imaging
C70582
Diagnostic Procedure
Vibration Response Imaging
CAM Multimodality Therapy
Complementary or Alternative Medical Procedure
Therapeutic or Preventive Procedure
C67018
owl:Class
CAM Multimodality Therapy
CL371509
CAM Multimodality Therapy
CAM Multimodality Therapy
Isometric Exercise
Muscle-Setting Exercise
C0022206
C21057
Static Exercise
Daily or Recreational Activity
Isometric Exercise
Isometric Exercise
Exercise
Isometrics
An exercise that is performed by exerting force against an immovable object or by holding an object in a static position.
Isometric Exercise
owl:Class
owl:Class
Nutrition, Fats, Polyunsaturated
Nutrition, Fats, Polyunsaturated
CL008802
Research Activity
Nutrition, Fats, Polyunsaturated
Nutrition, Fats
Study of polyunsaturated fats in relation to cancer.
Nutrition, Fats, Polyunsaturated
C16111
Ribonucleotide Reductase Messenger RNA Expression Measurement
Ribonucleotide Reductase Messenger RNA Expression Measurement
Ribonucleotide Reductase Messenger RNA Expression Measurement
owl:Class
CL387639
C79096
Laboratory Procedure
Ribonucleotide Reductase Messenger RNA Expression Measurement
RNA Analysis
<def-source>CDISC</def-source><def-definition>A study of the degree to which or rate at which a drug or other substance is absorbed or becomes available at the site of physiological activity after administration. (NCI)</def-definition>
A study of the degree to which, or rate at which, a drug or other substance is absorbed or becomes available at the site of physiological activity after administration.
CDISC SDTM Terminology
CDISC SDTM Trial Type Terminology
owl:Class
Bioavailability Study
CDISC
Bioavailability Study
Research Activity
Human Pharmacology Study
BIO-AVAILABILITY
Bioavailability Study
C49664
CL354988
Bioavailability Study
Clinical Data Interchange Standards Consortium Terminology
Anion Gap
Anion Gap Measurement
Blood Chemistry Measurement
The determination of the concentrations of anions, such as chloride and bicarbonate, subtracted from the concentration of cations, such as sodium and potassium, present in a plasma or serum sample.
C74685
Laboratory Procedure
ANIONG
Clinical Data Interchange Standards Consortium Terminology
Anion Gap Measurement
CDISC
owl:Class
CDISC SDTM Terminology
Anion Gap Measurement
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Name
<def-source>CDISC</def-source><def-definition>A computed estimate of the unmeasured anions (those other than the chloride and bicarbonate anions) in a biological specimen.</def-definition>
CDISC SDTM Laboratory Test Terminology by Code
Anion Gap Measurement
C0201889
RETIRBC
Blood Cell Count Ratio Measurement
Clinical Data Interchange Standards Consortium Terminology
CDISC
CDISC SDTM Terminology
CDISC SEND Terminology
Reticulocyte to Erythrocyte Ratio
owl:Class
CDISC SDTM Laboratory Test Terminology by Code
C64828
Reticulocytes/Erythrocytes
CDISC SDTM Laboratory Test Terminology by Name
Reticulocyte to Erythrocyte Ratio
The determination of the ratio of reticulocytes compared to erythrocytes in a blood sample. The measurement may be expressed as a ratio or percentage.
Reticulocyte to Erythrocyte Ratio
CL370494
Laboratory Procedure
<def-definition>A relative measurement (ratio or percentage) of reticulocytes to erythrocytes in a biological specimen.</def-definition><def-source>CDISC</def-source>
Reticulocyte to Erythrocyte Ratio
C53312
Retrospective Study
owl:Class
Retrospective Study
Retrospective Study
Retrospective Study
C0035363
Research Activity
Longitudinal Study
Therapeutic Exploratory Study
Therapeutic Exploratory Study
owl:Class
C39538
CL323633
Research Activity
A study that explores the use of the particular medical technology for the targeted indication at the earliest stages of clinical development in well-defined patient populations. The exploratory study determines treatment regimen for subsequent studies, and provides basis for confirmatory study design, endpoints, and methodologies.
Therapeutic Exploratory Study
Therapeutic Exploratory Study
Therapeutic Clinical Trial
C0872152
Research Activity
Design, identification, synthesis, extraction, purification, modification, or characterization of potential anticancer agents; studies of their metabolism, distribution, excretion, physiological effects, molecular interactions, structural analysis, toxicity, mechanism of action, antitumor effects in vivo (nonhuman species) or in vitro (human or nonhuman), and phase I and phase II clinical trials.
Drug Development
C15760
Research Activity
owl:Class
Drug Development
Drug Development
Drug Development
Eye Examination
Eye Examination
owl:Class
C38060
C0200149
Diagnostic Procedure
A test performed by an ophthalmologist or optometrist assessing vision and ability to focus on and discern objects, as well as other tests and examinations pertaining to the eyes.
Eye Exam
Eye Examination
Eye Examination
Medical Examination
Proctoscopy with Biopsy
CL354190
Proctoscopy with Biopsy
Proctoscopy with Biopsy
Removal of anal tissue, for microscopic examination.
Procedure_Has_Partially_Excised_Anatomy only Anus
Diagnostic Procedure
C51670
Proctoscopy with Biopsy
owl:Class
Endoscopic Biopsy
Technology Development
Phenomenon or Process
C15434
C0242804
Technology Transfer
The process of converting scientific findings from research laboratories into useful products by the commercial sector.
Technology Transfer
owl:Class
Technology Transfer
Technology Transfer
Creatine Kinase MB Measurement
CDISC SEND Terminology
Creatine Kinase MB
CDISC SDTM Laboratory Test Terminology by Name
C64491
Creatine Kinase Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the heterozygous MB-type creatine kinase in a biological specimen.</def-definition>
C0523584
CDISC SDTM Terminology
Creatine Kinase MB Measurement
A quantitative measurement of the amount of heterozygous MB-type creatine kinase present in a sample.
Laboratory Procedure
owl:Class
Creatine Kinase MB Measurement
Clinical Data Interchange Standards Consortium Terminology
Creatine Kinase MB Measurement
CDISC
CKMB
CDISC SDTM Laboratory Test Terminology by Code
The determination of the amount of prothrombin fragments 1 and 2 present in a sample.
Prothrombin Fragments 1 and 2 Measurement
Protein or Enzyme Type Measurement
Prothrombin Fragments 1 and 2 Measurement
Prothrombin Fragments 1 and 2 Measurement
Prothrombin Fragments 1 and 2 Measurement
C82034
owl:Class
C0034020
Public Health Administration
<def-source>MSH2001</def-source><def-definition>Management of public health organizations or agencies.</def-definition>
Public Health Administration
Administrative Activity
Public Health Administration
Public Health Administration
owl:Class
C15309
Health Care Activity
Isolated Hepatic Perfusion
Isolated Hepatic Perfusion
Therapeutic or Preventive Procedure
isolated hepatic perfusion
Isolated Hepatic Perfusion
<def-source>NCI-GLOSS</def-source><def-definition>A procedure in which a catheter is placed into the artery that provides blood to the liver; another catheter is placed into the vein that takes blood away from the liver. This temporarily separates the liver's blood supply from blood circulating throughout the rest of the body and allows high doses of anticancer drugs to be directed to the liver only.</def-definition>
Isolated Perfusion
CL031826
C15686
Isolated Hepatic Perfusion
owl:Class
Interferon Alpha Measurement
Interferon Alpha Measurement
Interferon Alpha Measurement
Interferon Measurement
Interferon Alpha Measurement
C81994
owl:Class
The determination of the amount of interferon alpha present in a sample.
Cystectomy
Cystectomy
Therapeutic or Preventive Procedure
C15217
<def-source>MSH2001</def-source><def-definition>Used for excision of the urinary bladder.</def-definition>
owl:Class
C0010651
cystectomy
Urologic Surgical Procedure
<def-source>NCI-GLOSS</def-source><def-definition>(sis-TEK-toe-mee) Surgery to remove all or part of the bladder.</def-definition>
Cystectomy
Cystectomy
Procedure_Has_Excised_Anatomy only Bladder
CYTRPHOS
Crystal Growth Measurement
CL384773
The determination of the amount of triple phosphate crystals present in a urine sample.
owl:Class
CDISC SDTM Laboratory Test Terminology by Code
Urine Chemistry Measurement
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Name
Clinical Data Interchange Standards Consortium Terminology
Triple Phosphate Crystal Measurement
Triple Phosphate Crystal Measurement
CDISC SDTM Terminology
<def-source>CDISC</def-source><def-definition>A measurement of the triple phosphate crystals present in a urine specimen.</def-definition>
CDISC
Triple Phosphate Crystals
Triple Phosphate Crystal Measurement
Triple Phosphate Crystal Measurement
Laboratory Procedure
C74756
Risk-Adjusted Mortality Rate
Risk-Adjusted Mortality Rate
Death Rate
C53361
Risk-Adjusted Mortality Rate
owl:Class
CL356521
Risk-Adjusted Mortality Rate
Quantitative Concept
Removal of tissue from the anus for microscopic examination.
Biopsy of Anus
owl:Class
Biopsy of Anus
Biopsy of Anus
Biopsy of Anus
Biopsy
C0193114
C51586
Anal Biopsy
Diagnostic Procedure
Procedure_Has_Partially_Excised_Anatomy only Anus
Enlargement Of Surgical Incision
Enlargement Of Surgical Incision
CL354545
Enlargement Of Surgical Incision
Surgical Procedure
Therapeutic or Preventive Procedure
Enlargement Of Surgical Incision
C50835
owl:Class
Principal Component
owl:Class
Principal Component
Principal Component
CL360712
C60694
Quantitative Concept
Principle Component
Principal Component
Statistical Technique
One of the axes representing the projection of varience resulting from principal component analysis.
owl:Class
Hydromorphone Measurement
CDISC SDTM Terminology
Hydromorphone Measurement
CDISC SDTM Laboratory Test Terminology by Name
Opioid Measurement
CDISC SEND Terminology
C74880
C0524151
Clinical Data Interchange Standards Consortium Terminology
HYDMRPHN
Hydromorphone
Hydromorphone Measurement
CDISC SDTM Laboratory Test Terminology by Code
The determination of the amount of hydromorphone present in a sample.
Hydromorphone Measurement
Laboratory Procedure
<def-definition>A measurement of the hydromorphone present in a biological specimen.</def-definition><def-source>CDISC</def-source>
Clinical Study Safety Issue
Intellectual Product
Clinical Study Safety Issue
owl:Class
Clinical Study Safety Issue
Regulatory Assessment
Clinical Study Safety Issue
CLINICAL STUDY SAFETY ISSUE
C82454
Activity
The chemical elements of which a nanoparticle is composed.
Nanoparticle Chemical Characterization
Nanoparticle Functionality
owl:Class
Nanoparticle Functionality
C62335
CL364928
Nanoparticle Functionality
Nanoparticle Functionality
C48611
Elliptical Skin Excision
Elliptical Skin Excision
CL342171
Skin Excision
owl:Class
Elliptical Skin Excision
Therapeutic or Preventive Procedure
A surgical procedure in which the skin is cut in a geometrical fashion resembling an ellipse.
Elliptical Skin Excision
Red Reflex Vision Test
owl:Class
Red Reflex Vision Test
An optic examination in which an ophthalmoscope or retinoscope is placed approximately 30cm from the eye to visualize whether a reddish hue is reflected from the retina.
Red Reflex Vision Test
Diagnostic Procedure
Red Reflex Vision Test
C81283
Eye Examination
Newborn Screening
C0439805
Tumor Debulking
Tumor Debulking
C15749
tumor debulking
Tumor Debulking
<def-source>NCI-GLOSS</def-source><def-definition>Surgically removing as much of the tumor as possible.</def-definition>
Therapeutic or Preventive Procedure
Tumor Debulking
owl:Class
Debulking Procedure
Laser-Induced Fluorescence Endoscopy
Diagnostic Procedure
C20203
Laser-Induced Fluorescence Endoscopy
Endoscopic Procedure
LIFE
Laser-Induced Fluorescence Endoscopy
owl:Class
CL025943
Laser-Induced Fluorescence Endoscopy
Procedure_Has_Completely_Excised_Anatomy only 'Prostatic Urethra'
Radical Prostatectomy
Radical Prostatectomy
Procedure_Has_Completely_Excised_Anatomy only 'Prostate Gland'
owl:Class
Prostatectomy
Radical Prostatectomy
Procedure_Has_Partially_Excised_Anatomy only 'Seminal Vesicle'
Procedure_Has_Excised_Anatomy only 'Intra-Abdominal Lymph Node'
Radical Prostatectomy
radical prostatectomy
C0194810
Prostatovesiculectomy
C15399
Procedure_Has_Partially_Excised_Anatomy only 'Vas Deferens'
Therapeutic or Preventive Procedure
<def-source>NCI-GLOSS</def-source><def-definition>(RAD-ih-kal pros-ta-TEK-toe-mee) Surgery to remove the entire prostate. The two types of radical prostatectomy are retropubic prostatectomy and perineal prostatectomy.</def-definition>
Laboratory Procedure
CDISC
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
C64825
CDISC SDTM Terminology
Myeloblast to Leukocyte Ratio
The determination of the ratio of myeloblasts compared to leukocytes in a blood sample. The measurement may be expressed as a ratio or percentage.
Myeloblast to Leukocyte Ratio
MYBLALE
Clinical Data Interchange Standards Consortium Terminology
<def-definition>A relative measurement (ratio or percentage) of the myeloblasts to leukocytes in a biological specimen.</def-definition><def-source>CDISC</def-source>
Blood Cell Count Ratio Measurement
Myeloblast to Leukocyte Ratio
owl:Class
CL370260
Myeloblast to Leukocyte Ratio
Myeloblasts/Leukocytes
owl:Class
C15498
unknown status, progesterone receptor
Progesterone Receptor Status Unknown
Progesterone Receptor Status Unknown
Progesterone Receptor Status Unknown
Progesterone Receptor Status Unknown
Clinical Attribute
CL029644
Progesterone Receptor Status
C15490
Therapeutic or Preventive Procedure
CL029589
Monoclonal Antibody Therapy
Monoclonal Antibody Therapy
Monoclonal Antibody Therapy
Monoclonal Antibody Therapy
owl:Class
Antibody Therapy
Quantitative Concept
owl:Class
Population Frequency
Population Frequency
Statistical Technique
Population Frequency
C0017270
Allele Frequency
Gene Frequency
C45373
A description of the relative rate of occurrence of specific alleles, traits, or other factors within a population of organisms.
Population Frequency
total estrogen blockade
Antiestrogen Therapy
owl:Class
C15700
Total Estrogen Blockade
CL031873
Total Estrogen Blockade
Total Estrogen Blockade
Total Estrogen Blockade
Therapeutic or Preventive Procedure
<def-source>NCI-GLOSS</def-source><def-definition>Therapy used to eliminate estrogen in the body. This may be done with surgery, radiation therapy, chemotherapy, or a combination of these procedures.</def-definition>
Bowel Obstruction Management
Techniques and procedures for maintaining the health of patients with obstructive bowel disease.
Therapeutic or Preventive Procedure
owl:Class
Gastrointestinal Complications Management
Bowel Obstruction Management
Bowel Obstruction Management
C51995
CL353159
Bowel Obstruction Management
Conceptual Entity
Natural History and Cofactors
Natural History
2B2; Risk Assessment and Prevention; Population-Based research: Natural History, Transmission, Risk Factors; Transmission; Natural History and Cofactors
Elucidation and description of disease progress
C16136
Natural History and Cofactors
owl:Class
Natural History and Cofactors
Natural History and Cofactors
CL014076
owl:Class
Therapeutic or Preventive Procedure
C71727
CL378255
Breathing-Synchronized Delivery Tomotherapy
BSD Tomotherapy
Breathing-Synchronized Delivery Tomotherapy
Breathing-Synchronized Delivery Tomotherapy
Breathing-Synchronized Delivery Tomotherapy
Tomotherapy
Cancer Research
Self-identified projects in the Biochemistry and Pharmacology Cancer Activity.
Drug Discovery Groups
C15803
CL000335
Drug Discovery Groups
owl:Class
Drug Discovery Groups
Occupational Activity
Drug Discovery Groups
A technique using X-ray diffraction to characterize the crystallographic structure, size, and orientation in crystallized or powdered solid samples. It can be used to identify unknown substances or to determine the composition of a heterogeneous mixture of solids.
owl:Class
C1135961
Powder Diffraction
Laboratory Procedure
Powder Diffraction
X-Ray Crystallography
C78872
Powder Diffraction
Research Activity
Powder Diffraction
Visit
Personal Behavior
The act of going to see some person or place or thing; it can cover a short or long period but refers to a non-permanent arrangement.
Visits
Visit
Individual Behavior
C25716
CL052808
Visit
Visit
owl:Class
Zeta Potential Analysis
Laboratory Procedure
CL387723
Laser Doppler Velocimetry-Phase Analysis Light Scattering
Laser Doppler Velocimetry-Phase Analysis Light Scattering
owl:Class
A technique that combines laser Doppler velocimetry and phase analysis light scattering to determine the zeta potential of a sample.
Light Scattering
Research Activity
Laser Doppler Velocimetry-Phase Analysis Light Scattering
C78870
Laser Doppler Velocimetry-Phase Analysis Light Scattering
Inserted
The act of putting one thing into another.
C48685
Activity
Insertion
Instruction Imperative
Insert
C0441587
Insertion
Insertion
owl:Class
Action
Insertion
Procedure_Has_Partially_Excised_Anatomy only 'Left Breast'
Bilateral Reduction Mammoplasty
Bilateral Reduction Mammoplasty
Surgery to reduce the size of both breasts.
Therapeutic or Preventive Procedure
C51935
Bilateral Reduction Mammoplasty
Reduction Mammoplasty, Bilateral
Bilateral Reduction Mammoplasty
CL354431
Reduction Mammoplasty
Procedure_Has_Partially_Excised_Anatomy only 'Right Breast'
owl:Class
Activity
C64913
Instruction Imperative
Instruction Imperative
Action
Instruction Imperative
Instruction Imperative
CL370440
owl:Class
Instruction Imperative
Sniff
owl:Class
C65098
Sniff
CL370346
Activity
Sniff
Sniff
Special Diet Therapy
C0184626
Therapeutic or Preventive Procedure
Special Diet Therapy
Dietary Intervention
Special Diet Therapy
C15383
A form of therapy which includes dietary approaches and special diets that are applied as alternative therapies for risk factors or chronic disease in general.
owl:Class
Special Diet Therapy
Exponential Distribution
owl:Class
A family of continuous probability distribution functions, whose shape is determined by its rate parameter. It has been described as the continuous analog of the geometric distribution.
C53222
Exponential Distribution
Continuous Distribution
Quantitative Concept
CL356431
Exponential Distribution
Exponential Distribution
The act of carrying into effect.
CL342179
Action
Implementation
Implementation
Implementation
owl:Class
Activity
C47899
Implementation
CL355055
Double Lung Transplantation
Procedure_Has_Completely_Excised_Anatomy only 'Right Lung'
owl:Class
Double Lung Transplant
Double Lung Transplantation
Procedure_Has_Completely_Excised_Anatomy only 'Left Lung'
Therapeutic or Preventive Procedure
Double Lung Transplantation
C51790
Double Lung Transplantation
Lung Transplantation
Compression
Compression
owl:Class
Phenomenon or Process
Compression
Action
Compression
C41208
The act, process, or result of pressing together, flattening, or condensing, particularly, increasing an external physical pressure on a body structure. Also refers to the reduction in the volume of a body or substance and augmentation of its density due to pressure.
C0728907
owl:Class
Therapeutic or Preventive Procedure
Procedure_Has_Excised_Anatomy only 'Pelvic Lymph Node'
Pelvic Lymphadenectomy
Pelvic Lymphadenectomy
Diagnostic Procedure
Pelvic Lymphadenectomy
Lymphadenectomy
C51896
Surgical removal of one or more pelvic lymph nodes.
Pelvic Lymphadenectomy
Excision Pelvic Lymph Nodes
CL353592
owl:Class
C70819
CL375966
Clinical Study by Targeted Disease or Condition
Clinical Study by Targeted Disease or Condition
Research Activity
Clinical Study by Targeted Disease or Condition
Clinical Trial
Clinical Study by Targeted Disease or Condition
Digestion
Digestion Treatment
Protein Digestion
Protein Digestion
Protein Digestion
Research Technique
CL376084
Protein Digestion
Research Activity
A technique for proteolysis of proteins into peptides by treatment with any of various enzymes.
owl:Class
C70845
Flurazepam Measurement
C0202388
Flurazepam Measurement
The determination of the amount of flurazepam present in a sample.
Flurazepam Measurement
owl:Class
Flurazepam Measurement
C75373
Benzodiazepine Measurement
Laboratory Procedure
Endocervical Biopsy
owl:Class
CL355096
C51629
Cervical Biopsy
Removal of tissue from the endocervix for microscopic examination.
Procedure_Has_Partially_Excised_Anatomy only Endocervix
Endocervical Biopsy
Endocervical Biopsy
Diagnostic Procedure
Endocervical Biopsy
Procedure_Has_Target_Anatomy only Vein
Arteriovenous Shunt Procedure
Therapeutic or Preventive Procedure
Arteriovenous Shunt Procedure
Arteriovenous Shunt Procedure
Cardiovascular Surgical Procedure
owl:Class
Procedure_Has_Target_Anatomy only Artery
Arteriovenous Shunt Procedure
Surgical creation of a connection between an artery and a vein, often done for the purpose of hemodialysis.
C52000
CL354383
A clinical study that demonstrates or confirms therapy efficacy, establish regimen safety profile and dose-response relationship. The Confirmatory Study provides basis for assessing the risk-benefit relationship to support therapy licensing.
Therapeutic Confirmatory Study
CL323632
Therapeutic Confirmatory Study
owl:Class
C39537
Research Activity
Therapeutic Confirmatory Study
Therapeutic Clinical Trial
Therapeutic Confirmatory Study
OSMLTY
Osmolality Measurement
Osmolality Measurement
<def-definition>A measurement of the osmoles of solute per unit of biological specimen.</def-definition><def-source>CDISC</def-source>
Osmolality Measurement
CDISC SEND Terminology
Osmolality Measurement
CDISC SDTM Terminology
Clinical Data Interchange Standards Consortium Terminology
owl:Class
The determination of the osmoles of solute per kilogram of solvent present in a sample.
C0201803
C74801
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
Chemistry Test
Osmolality
C54657
Correction
The act of offering an improvement to replace a mistake; setting right; something substituted for an error.
Correction
CL360618
Correction
owl:Class
Qualitative Concept
Change
Correction
owl:Class
Cancer Prevention
Bone Metastases Prevention
CL030291
Bone Metastases Prevention
Methods used to prevent the spread of cancer from a primary tumor site to the bone.
Bone Metastases Prevention
Therapeutic or Preventive Procedure
Bone Metastases Prevention
C15529
Prevention of Bone Metastases
Health Care Activity
C51688
Colonoscopic Polypectomy
Colonoscopic Polypectomy
Colonoscopic Polypectomy
Polypectomy
Endoscopic Biopsy
owl:Class
Complete or partial removal of a polypoid lesion from the mucosal surface of the large intestine.
Procedure_Has_Partially_Excised_Anatomy only 'Large Intestinal Mucosa'
Colonic Polypectomy
CL353266
Colonoscopic Polypectomy
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Terminology
Prolymphocytes/Lymphocytes
CL384338
owl:Class
<def-source>CDISC</def-source><def-definition>A relative measurement (ratio or percentage) of the prolymphocytes to all lymphocytes in a biological specimen.</def-definition>
The determination of the ratio of prolymphocytes compared to all lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
CDISC SDTM Laboratory Test Terminology by Code
Prolymphocyte to Lymphocyte Ratio Measurement
Blood Cell Count Ratio Measurement
Prolymphocyte to Lymphocyte Ratio Measurement
Prolymphocyte to Lymphocyte Ratio Measurement
CDISC SEND Terminology
Prolymphocyte to Lymphocyte Ratio Measurement
Laboratory Procedure
CDISC
C74651
CDISC SDTM Laboratory Test Terminology by Name
PROLYMLY
The determination of the amount of Pi glutathione-s-transferase present in a sample.
Protein or Enzyme Type Measurement
C80203
Laboratory Procedure
Pi Glutathione S-Transferase Measurement
Pi Glutathione S-Transferase Measurement
Pi Glutathione S-Transferase Measurement
Pi Glutathione S-Transferase Measurement
owl:Class
Do Not Mix
Instruction Imperative
Do Not Mix
Activity
owl:Class
C67003
Do Not Mix
Do Not Mix
CL371415
owl:Class
Skinfold Thickness Analysis
Skinfold Thickness Analysis
Skinfold Thickness Analysis
Skinfold Test
Diagnostic Procedure
C77537
Diagnostic Procedure
Techniques for estimating body fat whereby a pinch of skin is precisely measured by calipers at several standardized points on the body to determine the subcutaneous fat layer thickness. These measurements are converted to an estimated body fat percentage by an equation.
Skinfold Thickness Analysis
CL387358
High-Intensity Focused Ultrasound Ablation
C68681
Focused Ultrasound Therapy
Therapeutic or Preventive Procedure
HIFU
High-Intensity Focused Ultrasound Ablation
owl:Class
High-Intensity Focused Ultrasound Ablation
CL374323
High-Intensity Focused Ultrasound Ablation
owl:Class
Splenectomy
Therapeutic or Preventive Procedure
Abdominal Surgical Procedure
Procedure_Has_Excised_Anatomy only Spleen
C15328
Splenectomy
Surgical removal of part or all of the spleen.
Splenectomy
splenectomy
<def-source>NCI-GLOSS</def-source><def-definition>(splen-EK-toe-mee) An operation to remove the spleen.</def-definition>
C0037995
Splenectomy
Elucidate the pathogenic mechanisms of HIV-related opportunistic infections. Enhance a bidirectional flow between basic and clinical observations and intervention programs on HIV-related complications and foster interdisciplinary collaborations.
Biomedical Occupation or Discipline
Pathobiology of Wasting and Growth Retardation
Pathobiology of Wasting and Growth Retardation
Pathobiology of Wasting and Growth Retardation
CL000677
Pathobiology of Wasting and Growth Retardation
Translational Research
C15831
owl:Class
C20206
A procedure that detects early metastases to the lymph nodes of the axilla. A radioactive tracer material is injected into the tissue prior to surgery and an X-ray picture is taken to visualize the lymph node system. The surgeon uses a small probe to find the lymph node and if the sentinel lymph node is free of cancer, the other lymph nodes in the axilla may not need to be removed. This minimizes the risks and side effects of a full lymph node dissection.
<def-source>NCI-GLOSS</def-source><def-definition>The use of dyes and radioactive substances to identify the first lymph node to which cancer is likely to spread from the primary tumor. Cancer cells may appear first in the sentinel node before spreading to other lymph nodes and other places in the body.</def-definition>
Lymph Node Mapping
Sentinel Lymph Node Mapping
Sentinel Lymph Node Mapping
sentinel lymph node mapping
Sentinel Lymph Node Mapping
owl:Class
Sentinel Lymph Node Mapping
Diagnostic Procedure
CL025946
Scanning
Diagnostic Imaging
Radionuclide Imaging
radionuclide scanning
C62667
owl:Class
<def-source>NCI-GLOSS</def-source><def-definition>A test that produces pictures (scans) of internal parts of the body. The person is given an injection or swallows a small amount of radioactive material; a machine called a scanner then measures the radioactivity in certain organs.</def-definition>
Scintigraphy
Radionuclide Imaging
Radionuclide Imaging
Diagnostic Procedure
Radionuclide Scanning
C0034606
Radionuclide Imaging
Scan
An imaging technique that uses a small dose of a radioactive chemical (isotope) called a tracer that can detect sites of cancer growth, trauma, infection or degenerative disorders. The tracer, which is either injected into a vein or swallowed, travels through the bloodstream to the target organ, and emits gamma rays, which are detected by a gamma camera and analyzed by a computer to form an image of the target organ.
Therapeutic or Preventive Procedure
Prevention of Lung Cancer
Cancer Prevention
Prevention of Lung Cancer
Lung Cancer Prevention
Prevention of Lung Cancer
C15558
Prevention of Lung Cancer
owl:Class
CL030500
Molecular Biology Research Technique
RT-PCR
owl:Class
Polymerase Chain Reaction
C18136
Reverse Transcriptase-Polymerase Chain Reaction
Reverse Transcriptase-Polymerase Chain Reaction
Reverse Transcriptase-Polymerase Chain Reaction
A laboratory procedure in which an RNA strand is first transcribed into a DNA complement and then subjected to PCR amplification. Transcribing an RNA strand into a DNA complement is termed reverse transcription and is done by the enzyme reverse transcriptase.
C0599161
Reverse Transcriptase-Polymerase Chain Reaction
Laboratory Procedure
Diagnostic Procedure
Microscopic Autoradiography
Laboratory Procedure
C18638
Autoradiography
CL000082
Microscopic Autoradiography
Microscopic Autoradiography
Autoradiography, Microscopic
owl:Class
Microscopic Autoradiography
Autoradiographic analysis performed by mounting the object for microscopy (e.g., on a glass slide) and bathing the object with a photographic emulsion that will record radioactive disintegrations occurring at close proximity.
Virtual Colonoscopy
Diagnostic Procedure
C28395
CTC
owl:Class
Computed Tomography Colonography
<def-source>NCI-GLOSS</def-source><def-definition>A procedure in which a detailed picture of the colon is created by an x-ray machine linked to a computer.</def-definition>
Computed Tomography Colonography
An imaging technique of the colon involving helical computed tomography and computer software to generate high-resolution 2-dimensional and 3-dimensional images of the inner surface of the colon. These images are then interpreted by a radiologist to determine the presence of several types of abnormalities of the colon.
C0935912
computed tomographic colonography
Computed Tomography Colonography
Computed Tomography Colonography
computed tomography colography
Computed Tomography
<def-source>NCI-GLOSS</def-source><def-definition>A method under study to examine the colon by taking a series of x-rays (called a CT scan) and then using a high-powered computer to reconstruct 2-D and 3-D pictures of the interior surfaces of the colon from these x-rays. The pictures can be saved, manipulated to better viewing angles, and reviewed after the procedure, even years later. Also called virtual colonoscopy.</def-definition>
Dilation and Curettage
C0012358
Dilation and Curettage of the Uterus
Dilation and Curettage
Dilation and Curettage
Therapeutic or Preventive Procedure
C15226
Diagnostic Procedure
owl:Class
D and C
D&amp;C
Dilation and Curettage
<def-source>MSH2001</def-source><def-definition>Dilatation of the cervix uteri followed by a scraping of the endometrium with a curette.</def-definition>
dilation and curettage
<def-source>NCI-GLOSS</def-source><def-definition>(dye-LAY-shun and kyoo-reh-TAHZH) D&amp;C. A minor operation in which the cervix is expanded enough (dilation) to permit the cervical canal and uterine lining to be scraped with a spoon-shaped instrument called a curette (curettage).</def-definition>
Curettage Procedure
Classification
Surgical Procedure
Surgical Procedure by Method
Surgical Procedure by Method
C49165
Surgical Procedure by Method
Header_Concept
owl:Class
Surgical Procedure by Method
CL356080
Blood Cell Count Ratio Measurement
C79467
Large Unstained Cells to Leukocytes Ratio Measurement
LGLUCLE
CDISC SDTM Laboratory Test Terminology by Name
Clinical Data Interchange Standards Consortium Terminology
Large Unstained Cells/Leukocytes
Large Unstained Cells to Leukocytes Ratio Measurement
<def-definition>A relative measure (ratio or percentage) of the large unstained cells to leukocytes in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SEND Terminology
CDISC SDTM Terminology
Large Unstained Cells to Leukocytes Ratio Measurement
owl:Class
The determination of the ratio of large unstained cells compared to leukocytes present in a sample. The measurement may be expressed as a ratio or percentage.
Large Unstained Cells to Leukocytes Ratio Measurement
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Code
<def-definition>A measurement of the Vitamin A in a biological specimen.</def-definition><def-source>CDISC</def-source>
Vitamin A Measurement
Vitamin A
Clinical Data Interchange Standards Consortium Terminology
Laboratory Procedure
Vitamin A Measurement
C0373745
Vitamin Measurement
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Code
VITA
Retinol
The determination of the amount of Vitamin A present in a sample.
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Terminology
Vitamin A Measurement
owl:Class
Vitamin A Measurement
C74895
Donor Lymphocyte Infusion
DLI
Therapeutic or Preventive Procedure
<def-source>NCI-GLOSS</def-source><def-definition>A type of therapy in which lymphocytes from the blood of a donor are given to a patient who has already received a stem cell transplant from the same donor. The donor lymphocytes may kill remaining cancer cells. Donor lymphocyte infusion is used to treat chronic myelogenous leukemia (CML) that has come back and myeloma. It is being studied in the treatment of other types of cancer.</def-definition>
Donor Cellular Infusion
Donor Lymphocyte Infusion
Donor Leukocyte Infusion
Donor Lymphocyte Infusion
C0919689
owl:Class
C16145
Donor Lymphocyte Infusion
Leukocyte Therapy
donor lymphocyte infusion
Phototherapy
Photoimmunotherapy
CL371246
owl:Class
C66919
Therapeutic or Preventive Procedure
Photoimmunotherapy
Immunotherapy
Photoimmunotherapy
Photoimmunotherapy
Therapeutic or Preventive Procedure
neutropenia attenuation
C15474
owl:Class
Toxicity Attenuation
Hematologic Toxicity Attenuation
Hematologic Toxicity Attenuation
CL029172
Hematologic Toxicity Attenuation
Hematologic Toxicity Attenuation
CL370436
Instruction Imperative
owl:Class
Inhale
Inhale
Inhale
Activity
C64980
Inhale
Laboratory Procedure
Protein or Enzyme Type Measurement
Galanin Measurement
owl:Class
C80182
Galanin Measurement
The determination of the amount of galanin present in a sample.
Galanin Measurement
Galanin Measurement
Lactoferrin Measurement
Lactoferrin Measurement
Lactoferrin Measurement
Lactoferrin Measurement
The determination of the amount of lactoferrin present in a sample.
C82021
Protein or Enzyme Type Measurement
owl:Class
Activity
An indication that a medication schedule was modified by temporarily terminating a prescribed regimen of medication.
C49501
<def-source>CDISC</def-source><def-definition>An indication that a medication schedule was modified by temporarily terminating a prescribed regimen of medication. (NCI)</def-definition>
CDISC SDTM Action Taken with Study Treatment Terminology
CL355058
owl:Class
Clinical Data Interchange Standards Consortium Terminology
Action Taken with Study Treatment
Drug Interrupted
CDISC SDTM Terminology
Drug Interrupted
Drug Interrupted
CDISC
Drug Interrupted
DRUG INTERRUPTED
Osteopontin Staining Method
Special Histology Staining Method
Osteopontin Staining Method
An immunohistochemical procedure for identification of osteopontin, a highly phosphorylated, calcium binding sialoprotein. Elevation in osteopontin levels are seen during sepsis and metastatic cancers. It is used as a tumor marker.
C23031
owl:Class
OPN
Osteopontin Staining Method
Osteopontin Staining Method
Osteopontin
CL347301
Laboratory Procedure
Osteopontin Staining Method
C0079278
Gastrointestinal Endoscopy
owl:Class
Gastrointestinal Endoscopy
Health Care Activity
Procedure_Has_Target_Anatomy some 'Gastrointestinal Tract'
Enteroscopy
Gastrointestinal Endoscopy
Any endoscopic procedure that visualizes a part of the gastrointestinal tract.
Endoscopic Procedure
C78162
Gastrointestinal Endoscopy
C53988
Statistical Technique
Statistical Frequency
The ratio of the number of observations in a statistical category to the total number of observations.
Statistical Frequency
Statistical Frequency
CL357360
Frequency
owl:Class
Statistical Frequency
Quantitative Concept
Warthin-Starry Staining Method
C0523216
Warthin-Starry Staining Method
Warthin-Starry Staining Method
C23040
Warthin-Starry Staining Method
Warthin-Starry Staining Method
Warthin-Starry Staining
Special Histology Staining Method
Laboratory Procedure
owl:Class
A histopathological technique for staining spirochetes and other microorganisms. Commonly used for identification of Helicobacter pylori in gastritis and peptic ulcer disease.
Metamyelocytes
METAMY
C74615
CDISC SDTM Laboratory Test Terminology by Name
Clinical Data Interchange Standards Consortium Terminology
Metamyelocyte Count
CDISC SDTM Terminology
Leukocyte Count
Metamyelocyte Count
<def-source>CDISC</def-source><def-definition>A measurement of the metamyelocytes (small, myelocytic neutrophils with an indented nucleus) in a biological specimen.</def-definition>
CDISC SDTM Laboratory Test Terminology by Code
Metamyelocyte Count
C0455285
CDISC
CDISC SEND Terminology
Laboratory Procedure
owl:Class
Metamyelocyte Count
The determination of the number of metamyelocytes present in a sample.
Defer
owl:Class
Deferred
Hold back to a later time.
Defer
Activity
Deferral
Defer
Defer
Action
C79754
Laboratory Procedure
Interleukin 4
CL384314
Interleukin 4 Measurement
CDISC SDTM Terminology
INTLK4
Interleukin 4 Measurement
The determination of the amount of interleukin 4 present in a sample.
Interleukin 4 Measurement
C74832
CDISC SDTM Laboratory Test Terminology by Code
owl:Class
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
Cytokine Measurement
<def-definition>A measurement of the interleukin 4 in a biological specimen.</def-definition><def-source>CDISC</def-source>
Interleukin 4 Measurement
owl:Class
Instruction Imperative
C65046
Put
Put
Put
Place
CL370090
Activity
Put
Bioconductor caAffy Q-Spline Normalization
Activity
CL369467
Statistical Technique
Bioconductor caAffy Q-Spline Normalization
owl:Class
C63934
A method to normalize Affymetrix arrays to each other or to a set of target intensities, as defined in documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html
Bioconductor caAffy Q-Spline Normalization
Bioconductor caAffy Q-Spline Normalization
C16001
CL004035
Pediatric Clinics and Services
Health Care Activity
Hospice Planning/Development
Hospice Planning/Development
Hospice Planning/Development
Hospice Planning/Development
owl:Class
Assay
C63851
Photostability Test
Photostability Test
An assay or diagnostic test utilized to measure the level of degradation of a drug or material in the presence of ultraviolet, visible or infrared light.
CL366420
Photostability Test
Laboratory Procedure
owl:Class
Photostability Test
owl:Class
Injection Procedure
injection
<def-source>NCI-GLOSS</def-source><def-definition>Use of a syringe and needle to push fluids or drugs into the body; often called a "shot."</def-definition>
C1533685
Injectable
Therapeutic or Preventive Procedure
Injection Procedure
Injection
C28160
Injection Procedure
Therapeutic Procedure
Injection Procedure
owl:Class
CNS Affecting Drug Measurement
The determination of the amount of any drug that stimulates the central nervous system (CNS) present in a sample.
Laboratory Procedure
CNS Stimulant Drug Measurement
CNS Stimulant Drug Measurement
CNS Stimulant Drug Measurement
CL384618
CNS Stimulant Drug Measurement
C75342
Cardiovascular Surgical Procedure
Aortic Valve Replacement
Surgery performed with the purpose of replacing a degenerated, calcified, malformed, dysfunctional, etc. aortic valve with a bioprosthetic, homograft, or autograft valve.
Cardiac Therapeutic Procedure
C0003506
C50815
Aortic Valve Replacement
Procedure_Has_Completely_Excised_Anatomy only 'Aortic Valve'
Aortic Valve Replacement
owl:Class
Aortic Valve Replacement
Therapeutic or Preventive Procedure
Debridement
owl:Class
Debridement
Therapeutic or Preventive Procedure
CL353871
Surgical Procedure by Method
Debridement
Debridement
C51682
Disroportional Stratified Sampling
CL378013
Stratified Random Sampling
C71497
Disroportional Stratified Sampling
Disroportional Stratified Sampling
Disroportional Stratified Sampling
owl:Class
Quantitative Concept
C64930
owl:Class
Dissolve under Tongue
C1636188
Dissolve
Dissolve under Tongue
Activity
Dissolve under Tongue
Dissolve under Tongue
Infrared Radiation Therapy
Infrared Radiation Therapy
Therapeutic or Preventive Procedure
C71590
Infrared Radiation Therapy
Radiation Therapy
C0204032
Infrared Radiation Therapy
owl:Class
Adjuvant Radiation Therapy
owl:Class
Radiation Therapy
Adjuvant Radiation Therapy
Therapeutic or Preventive Procedure
Adjuvant Radiation Therapy
CL354327
Radiation therapy that is administered subsequent to the main treatment plan to minimize or prevent disease recurrence.
Adjuvant Radiation Therapy
C51987
Intact Parathyroid Hormone Measurement
Hormone Measurement
Intact Parathyroid Hormone Measurement
CDISC SEND Terminology
Intact Parathyroid Hormone Measurement
Intact Parathyroid Hormone Measurement
PTHI
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
C74789
<def-source>CDISC</def-source><def-definition>A measurement of the intact parathyroid hormone in a biological specimen.</def-definition>
owl:Class
Parathyroid Hormone, Intact
CDISC
The determination of the amount of intact parathyroid hormone present in a sample.
CL384776
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Terminology
C15389
Endoscopic Biopsy
Diagnostic Procedure
Endoscopy and Biopsy
Biopsy
Endoscopic Biopsy
Endoscopic Biopsy
Procedure_Has_Excised_Anatomy only Organ
Endoscopic Biopsy
C0184980
owl:Class
The removal of tissue specimens or fluid from the living body for microscopic examination, performed to establish a diagnosis. In the case of an endoscopic biopsy, an endoscope is used to obtain the sample.
prostate cancer screening
Diagnostic Procedure
Cancer Screening
Screening for Prostate Cancer
C15550
early detection of prostate cancer
owl:Class
Screening for Prostate Cancer
CL030492
Screening for Prostate Cancer
prostate cancer early detection
Screening for Prostate Cancer
<def-source>FDA</def-source><def-definition>Recalls are regulatory actions that enable FDA to remove a hazardous, potentially hazardous, or a misbranded product from the marketplace. Recalls are also used to convey additional information to the user concerning the safe use of the product. Either FDA or the manufacturer can initiate recalls.</def-definition>
C53609
Type Of Remedial Action ICSR Terminology
Remedial Action
Individual Case Safety Report Terminology
owl:Class
FDA
Recall
Governmental or Regulatory Activity
Recall
C0034770
Recall
Recall
A removal or correction of a marketed product that the FDA considers to be in violation of the laws it administers and against which the agency would initiate legal action, such as seizure. A recall may be a voluntary action conducted by the manufacturer, by FDA request, or by FDA order under statutory authority.
owl:Class
Linear Amplification Technique
Various methods for amplification of nucleic acid sequences by making many copies off the same template.
Molecular Biology Research Technique
Linear Amplification Technique
Gene Amplification Technique
CL374464
Linear Amplification Technique
Linear Amplification Technique
C68778
The determination of the amount of mid-molecule parathyroid hormone present in a sample.
Hormone Measurement
Mid-Molecule Parathyroid Hormone Measurement
C81965
owl:Class
Mid-Molecule Parathyroid Hormone Measurement
Mid-Molecule Parathyroid Hormone Measurement
Mid-Molecule Parathyroid Hormone Measurement
Amphetamine Measurement
Laboratory Procedure
Amphetamine Drug Class Measurement
Amphetamine Measurement
C75347
C0428221
owl:Class
The determination of the amount of amphetamine present in a sample.
Amphetamine Measurement
Amphetamine Measurement
Colonoscopy
owl:Class
Therapeutic Colonoscopy
Therapeutic Colonoscopy
C0554063
Therapeutic or Preventive Procedure
Therapeutic Endoscopic Procedure
Therapeutic Colonoscopy
Therapeutic Colonoscopy
C64959
Blood Component Removal
C0005791
Pheresis
C15191
Hemapheresis
Pheresis
FDA
pheresis
Patient Problem Codes FDA CDRH
<def-source>NCI-GLOSS</def-source><def-definition>(fer-E-sis) A procedure in which blood is collected, part of the blood such as platelets or white blood cells is taken out, and the rest of the blood is returned to the donor.</def-definition>
Apheresis
Blood Treatment
apheresis
Patient Code (Appendix B)
owl:Class
Pheresis
Health Care Activity
Pheresis
CL376083
Fit
Satisfy a condition or restriction.
C70826
Activity
Action
Fit
Fit
Fit
owl:Class
Research Activity
Clinical Trials Design
Clinical Trials Design
The detailed planning of studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects.
Clinical Trials Design
Study Design
Clinical Trials Design
C15787
owl:Class
CL000229
Radiation Therapy
CL371302
Therapeutic or Preventive Procedure
Proton Beam Radiation Therapy
Proton Beam Radiation Therapy
owl:Class
Proton Beam Radiation Therapy
Proton Beam Radiation Therapy
C66897
CL383674
Dental Curing
Dental Curing
Dental Curing
C73513
Therapeutic or Preventive Procedure
The process by which resin-based materials are polymerized to become rigid.
Dental Curing
owl:Class
Dental Procedure
CL014337
owl:Class
Stratification Factors
C16153
Stratification Factors
Clinical Trials Design
Stratification Factors
Stratification Factors
Selected pre-treatment factors by which patients are segregated to assure equal balance of these factors before randomization to the intervention arms of a clinical protocol.
Health Care Activity
colorectal cancer screening
Diagnostic Procedure
Screening for Colorectal Cancer
colorectal cancer early detection
Cancer Screening
owl:Class
Screening for Colorectal Cancer
C15549
Screening for Colorectal Cancer
Screening for Colorectal Cancer
CL030491
early detection of colorectal cancer
The act of distributing or spreading or apportioning.
Distribution
owl:Class
Distribution
C0037775
C45273
Action
Distribution
Distributed
Activity
Distribution
owl:Class
Action
To transfer from a local area to an external or distant area; to move data out of one file or system with the purpose of importing it into another file or system.
Export
EXPORT
Structured Product Labeling Business Operation Terminology
CL378357
C71586
Export
Activity
Export
Exported
FDA
Export
Cytogenetic Analysis
Cytogenetic Techniques
Cytogenetic Analysis
<def-source>MSH2001</def-source><def-definition>Examination of chromosomes to diagnose, classify, screen for, or manage genetic diseases and abnormalities. Following preparation of the sample, KARYOTYPING is performed and/or the specific chromosomes are analyzed.</def-definition>
Molecular Analysis
C0752095
Cytogenetic Analysis
C18280
Cytogenetic Analysis
Techniques for analysis of chromosomal and subchromosomal properties and structures, such as those to diagnose, classify, screen for, or manage genetic diseases and abnormalities.
owl:Class
Laboratory Procedure
C70962
Agent Administration
The act of the dispensing, applying, or tendering of something to another, such as administration of a medicine.
Agent Administration
Agent Administration
owl:Class
CL375927
Administration
Activity
Agent Administration
CL371456
Macrobiotics Therapy
Therapeutic or Preventive Procedure
Macrobiotics Therapy
C67023
Biologically Based Practices
owl:Class
Macrobiotics Therapy
Macrobiotics Therapy
Hairy Cells/Lymphocytes
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
CL384394
CDISC SDTM Terminology
Hairy Cell to Lymphocyte Ratio Measurement
<def-source>CDISC</def-source><def-definition>A relative measurement (ratio or percentage) of the hairy cells (b-cell lymphocytes with hairy projections from the cytoplasm) to all lymphocytes in a biological specimen .</def-definition>
CDISC
Hairy Cell to Lymphocyte Ratio Measurement
owl:Class
HRYCELY
C74640
Blood Cell Count Ratio Measurement
Hairy Cell to Lymphocyte Ratio Measurement
Laboratory Procedure
Hairy Cell to Lymphocyte Ratio Measurement
The determination of the ratio of hairy cells compared to lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
CL003161
Molecular Biology Technique
Molecular Genetic Technique
The methods and tools used for DNA analysis and manipulation.
Molecular Genetic Technique
Molecular Genetic Technique
Research Technique
Molecular Genetic Technique
owl:Class
C19235
Molecular Biology Research Technique
Molecular Technique
<def-source>CSP2000</def-source><def-definition>general heading term for drug abuse and alcoholism, and covering all other unhealthful uses of substances associated with psychological or physical dependence.</def-definition>
Personal Behavior
Substance Abuse
Maladaptive pattern of drug or alcohol use that may lead to social, occupational, psychological, or physical problems.
Substance Abuse
Substance Abuse
C18272
C0740858
owl:Class
Individual Behavior
Substance Abuse
Ancillary Study
owl:Class
Companion Protocol
Ancillary Study
CL004903
Research Activity
Ancillary Study
Ancillary Study
Clinical Study by Organizational Parameters
Studies which are secondary to another study.
C16041
C15701
total hysterectomy
<def-source>NCI-GLOSS</def-source><def-definition>Surgery to remove the entire uterus, including the cervix. Sometimes, not all of the cervix is removed.</def-definition>
Total Hysterectomy
owl:Class
Hysterectomy
Total Hysterectomy
Therapeutic or Preventive Procedure
Total Hysterectomy
complete hysterectomy
A surgical procedure to remove the uterine body and cervix. -- 2004
Total Hysterectomy
Procedure_Has_Completely_Excised_Anatomy only Uterus
C0677962
Uncertain Risk
C19785
owl:Class
Uncertain Risk
Uncertain Risk
Risk Estimate
Quantitative Concept
Uncertain Risk
CL008806
Basic behavioral studies designed to strengthen the understanding of the determinants and processes that influence cancer-related risk behaviors.
CL003274
C15942
Research Activity
Basic Behavioral Studies in Cancer-Related Behaviors
Basic Behavioral and Social Science Research
owl:Class
Basic Behavioral Studies in Cancer-Related Behaviors
Basic Behavioral Studies in Cancer-Related Behaviors
Basic Behavioral Studies in Cancer-Related Behaviors
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Name
CSRBC
owl:Class
RBC Casts
CL384424
The determination of the amount of red blood cell casts present in a urine sample.
CDISC SDTM Laboratory Test Terminology by Code
Urine Sediment Analysis Measurement
Red Blood Cell Cast Measurement
Clinical Data Interchange Standards Consortium Terminology
Red Blood Cell Cast Measurement
Red Blood Cell Cast Measurement
CDISC
Red Blood Cell Cast Measurement
C74772
<def-source>CDISC</def-source><def-definition>A measurement of the red blood cell casts present in a urine specimen.</def-definition>
Laboratory Procedure
CDISC SDTM Terminology
Oral Cancer Prevention
Prevention of Oral Cancer
C15708
Cancer Prevention
Prevention of Oral Cancer
Therapeutic or Preventive Procedure
Prevention of Oral Cancer
CL031980
Prevention of Oral Cancer
owl:Class
owl:Class
C62717
Therapeutic or Preventive Procedure
CL365405
Natural Killer Cell Therapy
Natural Killer Cell Therapy
Leukocyte Therapy
Natural Killer Cell Therapy
Natural Killer Cell Therapy
Quality Assurance
C15311
owl:Class
Quality Control
Clinical Data Interchange Standards Consortium Glossary Terminology
CDISC
Quality Control
C0034378
Activity
Quality Control
Clinical Data Interchange Standards Consortium Terminology
quality control (QC)
Quality Control
<def-source>CDISC</def-source><def-definition>The operational techniques and activities undertaken within the quality assurance system to verify that the requirements for quality of the trial related activities have been fulfilled. [ICH]</def-definition>
<def-source>MSH2001</def-source><def-definition>A system for verifying and maintaining a desired level of quality in a product or process by careful planning, use of proper equipment, continued inspection, and corrective action as required. (Random House Unabridged Dictionary, 2d ed)</def-definition>
C74856
Estriol Measurement
Estriol Measurement
Hormone Measurement
C0337435
CDISC SEND Terminology
Clinical Data Interchange Standards Consortium Terminology
owl:Class
Estriol Measurement
The determination of the amount of estriol hormone present in a sample.
CDISC SDTM Terminology
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Name
Estriol Measurement
CDISC SDTM Laboratory Test Terminology by Code
Estriol
ESTRIOL
Oestriol
<def-definition>A measurement of the estriol hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
The exchange of spoken words.
Speech
Organism Function
Talk
owl:Class
Communication
Speech
Talking
Speech
C0037817
C38025
Speech
Therapeutic Equivalency Study
Therapeutic Clinical Trial
CL354260
Therapeutic Equivalency Study
A study most often used to compare the efficacy of different formulations to treat a given disease. It is the testing of an old versus a new formulation in healthy volunteers or subjects with the disease under study and usually in one dose.
owl:Class
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Trial Type Terminology
BIO-EQUIVALENCE
Therapeutic Equivalency Study
C49665
<def-source>CDISC</def-source><def-definition>A study most often used to compare the efficacy of different formulations to treat a given disease. It is the testing of an old versus a new formulation in healthy volunteers or subjects with the disease under study and usually in one dose. (NCI)</def-definition>
CDISC SDTM Terminology
CDISC
Therapeutic Equivalency Study
Research Activity
Decortication
<def-source>MSH2002_06_01</def-source><def-definition>Partial or total removal, ablation, or destruction of the cerebral cortex; may be chemical. It is not used with animals that do not possess a cortex, i.e., it is used only with mammals.</def-definition>
decortication
C0007778
Decortication
Therapeutic or Preventive Procedure
owl:Class
<def-source>NCI-GLOSS</def-source><def-definition>(de-KOR-tih-KAY-shun) Removal of part or all of the external surface of an organ.</def-definition>
C28139
Surgical Procedure by Method
Decortication
Decortication
Orthodontic Treatment
en masse Movement
Therapeutic or Preventive Procedure
en masse Movement
en masse Movement
en masse Movement
en masse
owl:Class
Movement of goups of teeth as a unit as opposed to individually.
C82104
Advanced Manufacturing Technology
owl:Class
Advanced Manufacturing Technology
C15763
Phenomenon or Process
CL000032
Advanced Manufacturing Technology
Advanced Manufacturing Technology
Activities, including research and development efforts, leading to new or improved manufacturing processes, equipment, or techniques, as well as related activities to manage and deploy manufacturing technologies.
Technology Development
Research Activity
Urine 5-HIAA Measurement
Urine 5-Hydroxyindoleacetic Acid Measurement
Urine 5-Hydroxyindoleacetic Acid Measurement
A laboratory chemistry procedure measuring the level of 5-hydroxyindoleacetic acid in a 24-hour urine sample.
Urine 5-Hydroxyindoleacetic Acid Measurement
Urine 5-Hydroxyindoleacetic Acid Measurement
Laboratory Procedure
owl:Class
Urine Chemistry Measurement
C82376
Acquisition
Acquire
owl:Class
Acquisition
Obtain
C43384
Acquisition
Action
CL333535
Acquisition
The process by which something is acquired or obtained.
Activity
owl:Class
Removal of degenerated and necrotic epithelium and underlying connective tissue of a periodontal pocket in an effort to convert a chronic ulcerated wound to an acute surgical wound, thereby insuring wound healing and attachment or epithelial adhesion, and shrinkage of the marginal gingiva.
C63713
Subgingival Curettage
Therapeutic or Preventive Procedure
Subgingival Curettage
Curettage Procedure
Subgingival Curettage
C0038544
Subgingival Curettage
CL370558
Therapeutic Lymphadenectomy
Therapeutic Lymphadenectomy
Therapeutic Lymphadenectomy
Therapeutic or Preventive Procedure
Therapeutic Lymphadenectomy
C65003
Therapeutic Surgical Procedure
owl:Class
Lymphadenectomy
Repeat
Instruction Imperative
Repeat
owl:Class
Action
Repeat
C47886
C0205341
Replicate
Repeatedly
Repeat
Make or do or perform again.
Activity
Procedure_Has_Excised_Anatomy only Omentum
Omentectomy
Omentectomy
C51787
Partial or complete resection of the omentum.
Epiploectomy
Resection of Omentum
Omentectomy
C0198614
owl:Class
Abdominal Surgical Procedure
Omentectomy
Therapeutic or Preventive Procedure
owl:Class
Prior Therapy
Prior Gene Therapy
CL014626
Prior Gene Therapy
C16170
Prior Gene Therapy
Prior Gene Therapy
Clinical Attribute
owl:Class
The determination of the number of malignant cells present in a sample.
Malignant Cell Count
CDISC SDTM Laboratory Test Terminology by Name
CDISC
<def-source>CDISC</def-source><def-definition>A measurement of the malignant cells of all types in a biological specimen.</def-definition>
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Code
MLIGCE
CDISC SEND Terminology
Malignant Cell Count
C74660
Laboratory Procedure
Malignant Cells, NOS
CL384411
Cell Count
Malignant Cell Count
CDISC SDTM Terminology
Malignant Cell Count
Non-Parametric Regression Method
C53239
Non-Parametric Regression Method
Quantitative Concept
Non-Parametric Regression Method
Nonparametric Regression Method
owl:Class
CL355776
Regression Method
Non-Parametric Regression Method
Non-parametric regression methods are aimed at describing a relationship between the dependent and independent variables without specifying the form of the relationship between them a priori.
Surgical Procedure by Site or System
CL353454
C51559
Integumentary System Surgery
Integumentary System Surgery
Surgery on the skin (integument).
Integumentary System Surgery
owl:Class
Procedure_Has_Excised_Anatomy only Skin
Integumentary System Surgery
Therapeutic or Preventive Procedure
A procedure that uses sound waves to create a video image of the prostate gland. A small, lubricated probe placed into the rectum releases sound waves, which create echoes as they enter the prostate. Prostate tumors sometimes create echoes that are different from normal prostate tissue. The echoes that bounce back are sent to a computer that translates the pattern of echoes into a picture of the prostate.
Transrectal Ultrasound
Transrectal Ultrasound
owl:Class
Transrectal Ultrasound
CL032290
transrectal ultrasound
C18315
Transrectal Ultrasound
Diagnostic Procedure
<def-source>NCI-GLOSS</def-source><def-definition>A procedure used to examine the prostate. An instrument is inserted into the rectum, and sound waves bounce off the prostate. These sound waves create echoes, which a computer uses to create a picture called a sonogram.</def-definition>
Ultrasound Imaging
A relaxation technique used in management of stress, pain, and blood pressure. Its focus is on spontaneous movement, concentration, visual and auditory objectivity, controlled self-consciousness, and responsiveness to interpersonal relationships. (from Fleming)
Fleming Method Relaxation
Fleming Method Relaxation
Fleming Method
C21037
Relaxation Therapy
Fleming Method Relaxation
Mental Process
Fleming Method Relaxation
CL100605
owl:Class
Primer Extension
owl:Class
Primer Extension
C20614
Primer Extension
Laboratory Procedure
A method to synthesize cDNA for determining the 5'-untranslated region of a specific mRNA molecule through reverse transcription reaction using complementary oligonucleotides as primers.
Primer Extension
RNA Analysis
CL078012
Extracorporeal Photopheresis
Extracorporeal Photopheresis
Extracorporeal Photophoresis
C62729
Extracorporeal Photopheresis
C0206373
Photophoresis
<def-source>NCI-GLOSS</def-source><def-definition>A procedure in which blood is removed from the body and treated with ultraviolet light and drugs that become active when exposed to light. The blood is then returned to the body. It is being studied in the treatment of some blood and bone marrow diseases and graft-vs-host disease (GVHD).</def-definition>
Phototherapy
owl:Class
Therapeutic or Preventive Procedure
extracorporeal photopheresis
Extracorporeal Photopheresis
Laboratory Procedure
CL000114
Biotechnology, Mass Cell Culture
Cell Culture
Biotechnology, Mass Cell Culture
owl:Class
Techniques using equipment such as a hollow fiber apparatus or roller bottles for high volume maintenance or growth of animal, plant, or insect cells in vitro.
C18657
Biotechnology, Mass Cell Culture
Biotechnology, Mass Cell Culture
owl:Class
INFOODS
Research Activity
INFOODS was established in 1984 on the basis of the recommendations of an international group convened under the auspices of the United Nations University (UNU). Its goal was to stimulate and coordinate efforts to improve the quality and availability of food analysis data worldwide and to ensure that anyone anywhere would be able to obtain adequate and reliable food composition data. The system contains reliable data on the nutrient composition of foods consumed by people; the data sets are applicable in many areas - health assessment, the formulation of appropriate institutional and therapeutic diets, nutrition education, food and nutrition training, epidemiological research on relationships between diet and disease, plant breeding, nutrition labeling, food regulations, consumer protection, and agricultural goods and products, as well as for a variety of applications in trade, research, development, and assistance. (from INFOODS)
International Network of Food Data Systems
Research Activity
International Network of Food Data Systems
C68656
International Network of Food Data Systems
International Network of Food Data Systems
CL371919
CL035532
owl:Class
Diagnostic Procedure
C62697
Study of High Risk Factors
Study of High Risk Factors
Disease Screening
Study of High Risk Factors
Study of High Risk Factors
informed consent
<def-source>NCI-GLOSS</def-source><def-definition>A process in which a person learns key facts about a clinical trial, including potential risks and benefits, before deciding whether or not to participate in a study. Informed consent continues throughout the trial.</def-definition>
Health Care Activity
Personal Behavior
C16735
Informed Consent
C0021430
Informed Consent
Informed Consent
owl:Class
Informed Consent
Consent by a patient to a surgical or medical procedure or participation in a clinical study after achieving an understanding of the relevant medical facts and the risks involved.
C51765
Bilateral Salpingectomy with Oophorectomy
Bilateral Salpingectomy with Oophorectomy
owl:Class
Therapeutic or Preventive Procedure
Procedure_Has_Completely_Excised_Anatomy only 'Right Ovary'
CL354432
Bilateral Salpingectomy with Oophorectomy
Bilateral Salpingectomy with Oophorectomy
Salpingo-Oophorectomy
Surgery to remove both fallopian tubes, as well as both ovaries.
Procedure_Has_Completely_Excised_Anatomy only 'Right Fallopian Tube'
Procedure_Has_Completely_Excised_Anatomy only 'Left Ovary'
Procedure_Has_Completely_Excised_Anatomy only 'Left Fallopian Tube'
The act of bending one's back forward from the waist on down.
Stooping
C81003
owl:Class
Daily or Recreational Activity
Stooping
Stoop
Physical Activity
Stooping
Stooping
CDISC SDTM Laboratory Test Terminology by Code
Prolymphocytes
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Name
The determination of the number of prolymphocytes in a blood sample.
<def-source>CDISC</def-source><def-definition>A measurement of the prolymphocytes in a biological specimen.</def-definition>
CL384337
Prolymphocyte Count
Prolymphocyte Count
Lymphocyte Count
CDISC
C74620
owl:Class
CDISC SDTM Terminology
Laboratory Procedure
Prolymphocyte Count
PROLYM
Clinical Data Interchange Standards Consortium Terminology
Prolymphocyte Count
Plasma Enhancement
owl:Class
Plasma Enhancement
Therapeutic or Preventive Procedure
CL004129
Plasma Enhancement
Blood Transfusion
Plasma Enhancement
C16004
CDISC
Bicarbonate Measurement
C0202059
Bicarbonate Measurement
HCO3
CDISC SDTM Terminology
Chemistry Test
BICARB
Clinical Data Interchange Standards Consortium Terminology
Bicarbonate
The determination of the amount of bicarbonate present in a sample.
Bicarbonate Measurement
Bicarbonate Measurement
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Name
<def-source>CDISC</def-source><def-definition>A measurement of the bicarbonate in a biological specimen</def-definition>
owl:Class
CDISC SEND Terminology
C74667
CDISC SDTM Laboratory Test Terminology by Code
C62544
Periodontal Probing
Periodontal Treatment
owl:Class
The act of inserting a periodontal probe between the gingival tissues and the tooth.
Periodontal Probing
Periodontal Probing
CL365144
Periodontal Probing
Therapeutic or Preventive Procedure
Surveillance
Surveillance
Health Care Activity
Observational Study
Surveillance
Surveillance
The systematic collection, analysis, and interpretation of health data on an ongoing basis.
C0684245
owl:Class
Epidemiology / Surveillance
C15719
Dental Restoration
Therapeutic or Preventive Procedure
owl:Class
Full Crown
A dental restoration completely covering the aspect of the tooth normally covered by enamel.
Full Crown
CL370812
Full Crown
C66855
Full Crown
Biopsy
owl:Class
Mucosal Biopsy
Diagnostic Procedure
Biopsy of Mucosa
C51922
Biopsy of Mucosa
Biopsy of Mucosa
Removal of mucosal tissue for microscopic examination.
Biopsy of Mucosa
CL354996
Procedure_Has_Partially_Excised_Anatomy only Mucosa
Surgical removal of all or part of the ureter.
Procedure_Has_Excised_Anatomy only Ureter
C51637
Ureterectomy
Ureterectomy
Ureterectomy
CL356122
owl:Class
Urologic Surgical Procedure
Ureterectomy
Therapeutic or Preventive Procedure
Action
Tracking
Tracking
owl:Class
CL334879
Activity
Tracking
Tracking
The act or process of following a person, animal, or object through space or time.
C45275
Tobacco Use Policy Research
owl:Class
Research Activity
Tobacco Use Policy Research
Tobacco Use Policy Research
C15993
Policy Research
CL003973
Research studies that assess the effect of policies, including worksite, community, state and Federal policies, on tobacco initiation and use. (NCI/TRIP)
Tobacco Use Policy Research
Regulatory Assessment
Intellectual Product
Clinical Study Lack of Effectiveness
owl:Class
CLINICAL STUDY LACK OF EFFECTIVENESS
Clinical Study Lack of Effectiveness
Clinical Study Lack of Effectiveness
C82453
Clinical Study Lack of Effectiveness
C64865
CL370127
Endoscopic Procedure
Balloon-Guided Endoscopy
An endoscopic technique that allows deep intubation of the small intestine while using a standard endoscope. An inflatable balloon attached to the endoscope's tip acts as a stabilizer and a second balloon that is advanced ahead of the endoscope acts as a pulling device.
Balloon-Guided Endoscopic Procedure
Diagnostic Procedure
Balloon-Guided Endoscopic Procedure
owl:Class
Balloon-Guided Endoscopic Procedure
Balloon-Guided Endoscopic Procedure
Cytotoxic
C15681
Therapeutic or Preventive Procedure
Cytotoxic Chemotherapy
Chemotherapy
owl:Class
Cytotoxic Therapy
Cytotoxic Chemotherapy
C0677881
Cytotoxic Chemotherapy
Cytotoxic Chemotherapy
cytotoxic chemotherapy
<def-source>NCI-GLOSS</def-source><def-definition>Anticancer drugs that kill cells, especially cancer cells.</def-definition>
Endothelin-1 Measurement
Endothelin-1 Measurement
Protein or Enzyme Type Measurement
The determination of the amount of endothelin-1 present in a sample.
Endothelin-1 Measurement
Endothelin-1 Measurement
owl:Class
C82008
Nested Case-control Study
Nested Case-control Study
Research Activity
C48202
Nested Case-control Study
A study in which a group or cohort of individuals is followed for a certain length of time or until a specific outcome is reached. Studies of this type incorporate the strengths of both cohort and case-control studies but eliminates a portion of the methodologic challenges inherent in both types of studies.
Case-Control Study
Cohort Study
C0027775
Nested Case-control Study
owl:Class
Adoptive Immunotherapy
C15351
The concept does not refer to anticancer vaccines and immune modulation through the therapeutic use of cytokines, cell receptors, or other substances.
C0079613
Adoptive Immunotherapy
owl:Class
Therapeutic or Preventive Procedure
adoptive cellular immunotherapy
A technique for enhancing cell-mediated immunity by: 1) artificially increasing the number of specific immunocompetent cells through inoculation of either ex-vivo expanded primarily activated cytotoxic lymphocytes or genetically engineered lymphocytes with enhanced cytotoxic ability or 2) by altering tumor cells to make them more immunogenic.
Adoptive Immunotherapy
Passive Immunization
Immunotherapy
Adoptive Cell Immunotherapy
Adoptive Immunotherapy
Dual X-ray Absorptometry
Dual Energy X-ray Absorptometry
Dual X-ray Absorptometry
Diagnostic Imaging
owl:Class
C48789
A technique for scanning bone and measuring bone mineral density (BMD). A DXA scanner produces 2 X-ray beams, each with different energy levels. One beam is high energy while the other is low energy. The amount of x-rays that pass through the bone is measured for each beam. This will vary depending on the thickness of the bone. Based on the difference between the 2 beams, the bone density can be measured.
DXA
Diagnostic Procedure
Dual X-Ray Absorptiometry
Dual X-ray Absorptometry
DEXA
C1510486
Dual X-ray Absorptometry
C80188
HDL-Cholesterol Subclass 3 Measurement
HDL-Cholesterol Subclass 3 Measurement
owl:Class
HDL-Cholesterol Subclass 3 Measurement
Laboratory Procedure
HDL-Cholesterol Subclass 3 Measurement
The determination of the amount of HDL-cholesterol subclass 3 present in a sample.
Lipid Measurement
Chew
Chew
CL370614
owl:Class
Instruction Imperative
Chew
Chew
Activity
C64926
Diagnostic Radioimmunoguided Surgery
C65016
Radioimmunoguided Surgery
CL370147
Diagnostic Radioimmunoguided Surgery
Diagnostic Surgical Procedure
Diagnostic Radioimmunoguided Surgery
Diagnostic Radioimmunoguided Surgery
Diagnostic Procedure
owl:Class
Stock Recovery
Activity
C54700
owl:Class
Stock Recovery
Removal or correction by the manufacturer company of a product that has not been marketed or that has not left the direct control of the firm, i.e., the product is located on premises owned by, or under the control of, the firm and no portion of the lot has been released for sale or use.
Stock Recovery
Remedial Action
Stock Recovery
CL360533
<def-source>NCI-GLOSS</def-source><def-definition>Surgery to remove all or part of the liver.</def-definition>
C15249
C0019144
Hepatectomy
owl:Class
hepatectomy
Hepatectomy
Hepatectomy
Digestive System Surgery
Abdominal Surgical Procedure
Hepatectomy
Therapeutic or Preventive Procedure
Surgical removal of all or part of the liver.
Procedure_Has_Excised_Anatomy only Liver
owl:Class
Worksite Health Service
Worksite Health Service
Worksite Health Service
CL001112
Community Health Service
Worksite Health Service
Clinical service at the physical site of employment.
Health Care Activity
C15877
Cell Count
Oval Fat Body Measurement
Oval Fat Body Measurement
C81947
Oval Fat Body Measurement
The determination of the amount of oval-shaped fat bodies present in a sample.
owl:Class
Oval Fat Body Measurement
Nutrition, Protein/Amino Acids
Research Activity
Protein/Amino Acid Nutrition, Animal
C15844
Protein/Amino Acid Nutrition, Animal
Protein/Amino Acid Nutrition, Animal
CL000787
Study of dietary animal protein/amino acids in relation to cancer.
owl:Class
Protein/Amino Acid Nutrition, Animal
Vaccine Related Development, Cancer
Research Activity
Vaccine Related Development, Cancer
C15869
Vaccine Related Development, Cancer
Vaccine Development
Vaccine Related Development, Cancer
owl:Class
CL001071
Health Care Activity
Frontoparietal Craniotomy
C51578
Surgical creation of an opening in the fronto-parietal region of the skull.
Frontoparietal Craniotomy
CL353965
Frontoparietal Craniotomy
Craniotomy
owl:Class
Therapeutic or Preventive Procedure
Frontoparietal Craniotomy
Chemistry Test
C80210
The determination of the amount of zinc present in a sample.
Zinc Measurement
Zinc Measurement
Laboratory Procedure
Zinc Measurement
Zinc Measurement
owl:Class
Action
C75946
Convergence
Converging
Convergence
Convergence
C0443193
Convergence
owl:Class
The act of coming together and especially moving toward union or uniformity.
Activity
Converge
Radiation Conformal Therapy
C16035
3D-CRT
3-Dimensional Conformal Radiation Therapy
CL004819
3-Dimensional Conformal Radiation Therapy
3-Dimensional Conformal Radiation Therapy
Conformal Therapy
Therapeutic or Preventive Procedure
A process by which a dose of radiation is automatically shaped to closely conform to the entire volume of the tumor, so that surrounding normal tissue is spared and treatment toxicity is decreased.
Radiation Therapy
owl:Class
3-Dimensional Conformal Radiation Therapy
Pharmacological Study
owl:Class
Antitumor Drug Screening Assay
Antitumor Drug Screening Assay
Laboratory Procedure
C0013207
Antitumor Drug Screening Assay
Antitumor Drug Screening Assay
Drug Screening Assays, Antitumor
<def-source>MSH2001</def-source><def-definition>Methods of investigating the effectiveness of anticancer cytotoxic drugs and biologic inhibitors. These include in vitro cell-kill models and cytostatic dye exclusion tests as well as in vivo measurement of tumor growth parameters in laboratory animals.</def-definition>
C15229
DNA Therapy
owl:Class
Molecular Biology, Gene Therapy
C0017296
C15238
Therapeutic or Preventive Procedure
Intervention, Genetic
Gene Therapy
Gene Transfer Procedure
Application of genetic material (usually DNA) into cells in order to permanently correct an inherited disease or an acquired disease such as cancer. The genetic material as 'naked' DNA can be delivered into the cells alone or can be delivered into cells by different types of vectors such as viruses which may contain DNA or RNA. Gene therapy techniques attempt to replace a faulty/missing gene associated with a particular disease, mediate localized delivery of a protein producing specified therapeutic effects, or introduce new cellular functions. Gene therapies are designed to deliver genetic material into somatic cells and not germ cells, so that only cells of patients and not those of their offspring contain and express the genetic material delivered. (NCI04)
Biological Therapy
<def-source>NCI-GLOSS</def-source><def-definition>Treatment that alters a gene. In studies of gene therapy for cancer, researchers are trying to improve the body's natural ability to fight the disease or to make the cancer cells more sensitive to other kinds of therapy.</def-definition>
gene therapy
Gene Therapy
Gene Therapy
Gene Therapy
Colony-Forming Unit-Granulocyte Macrophage Assay
A functional (qualitative) as well as quantitative assay that is utilized as an indicator of granulopoiesis reconstitution.
Colony Forming Unit Granulocyte Macrophage Assay
Colony-Forming Unit-Granulocyte Macrophage Assay
Cellular Assay
Research Activity
Colony-Forming Unit-Granulocyte Macrophage Assay
Colony-Forming Unit-Granulocyte Macrophage Assay
C0201610
owl:Class
CFU-GM Assay
Colony Forming Unit-Granulocyte Macrophage Assay
C63799
CDISC SDTM Terminology
<def-definition>A measurement of the interleukin 11 in a biological specimen.</def-definition><def-source>CDISC</def-source>
CL384288
Interleukin 11 Measurement
Clinical Data Interchange Standards Consortium Terminology
Cytokine Measurement
The determination of the amount of interleukin 11 present in a sample.
CDISC SDTM Laboratory Test Terminology by Name
owl:Class
INTLK11
Laboratory Procedure
Interleukin 11 Measurement
Interleukin 11 Measurement
CDISC SDTM Laboratory Test Terminology by Code
Interleukin 11
Interleukin 11 Measurement
C74807
CDISC SEND Terminology
cDNA Expression
Molecular Genetic Technique
CL000182
cDNA Expression
CDNA expressed as protein formation
cDNA Expression
owl:Class
Molecular Biology Research Technique
cDNA Expression
C18687
H and E
Hematoxylin and Eosin Staining Method
Hematoxylin and Eosin Staining Method
HE
Hematoxylin and Eosin Staining Method
Hematoxylin and Eosin Staining Method
Routine Histology Staining Method
Laboratory Procedure
Hematoxylin and Eosin
Hematoxylin-and-eosin, or H&amp;E, is a routine staining procedure of tissue sections. This staining method uses two separate dyes, one staining the nucleus and the other staining the cytoplasm and connective tissue. Hematoxylin is a dark purplish dye that stains the chromatin (nuclear material) within the nucleus. Eosin is an orangish-pink to red dye that stains the cytoplasmic material including connective tissue and collagen.
C23011
C0523207
Hematoxylin and Eosin Staining Method
owl:Class
Mediastinoscopy
<def-source>NCI-GLOSS</def-source><def-definition>(MEE-dee-a-stin-AHS-ko-pee) A procedure in which a tube is inserted into the chest to view the organs in the area between the lungs and nearby lymph nodes. The tube is inserted through an incision above the breastbone. This procedure is usually performed to get a tissue sample from the lymph nodes on the right side of the chest.</def-definition>
Procedure_Has_Target_Anatomy only Mediastinum
mediastinoscopy
Endoscopic examination of the mediastinum.
Mediastinoscopy
Diagnostic Procedure
Mediastinoscopy
Thoracoscopy
Endoscopic Exploration of Mediastinum
C16829
C0025065
owl:Class
Mediastinoscopy
Cytokeratin-14 Staining Method
Cytokeratin 14
Cytokeratin 14 Staining Method
Special Histology Staining Method
C23025
Cytokeratin-14 Staining Method
Cytokeratin-14 Staining Method
C1511612
Cytokeratin-14 Staining Method
An immunohistochemical technique to detect cytokeratin14,an intermediate filament protein, using monoclonal antibody to cytokeratin 14. The technique is used in diagnostic histopathology to identify early squamous metaplasia.
Cytokeratin 14 Staining Method
Laboratory Procedure
owl:Class
CK14
Monitoring
Action
Monitoring
The act of observing something (and sometimes keeping a record of it).
C0150369
Monitoring
owl:Class
Monitoring
Activity
C61256
Hydrocodone Measurement
CDISC SDTM Terminology
<def-definition>A measurement of the hydrocodone present in a biological specimen.</def-definition><def-source>CDISC</def-source>
owl:Class
Clinical Data Interchange Standards Consortium Terminology
Opioid Measurement
CDISC SEND Terminology
HYDCDN
Hydrocodone Measurement
The determination of the amount of hydrocodone present in a sample.
Hydrocodone Measurement
Hydrocodone Measurement
C0524150
CDISC SDTM Laboratory Test Terminology by Name
Hydrocodone
Laboratory Procedure
C74879
CDISC SDTM Laboratory Test Terminology by Code
Diagnostic Colonoscopy
Colonoscopy
Diagnostic Colonoscopy
Diagnostic Procedure
owl:Class
Diagnostic Colonoscopy
C64944
Diagnostic Colonoscopy
C0400018
Diagnostic Endoscopic Procedure
Monitoring for Recurrence
owl:Class
CL000562
Monitoring for Recurrence
Monitoring for Recurrence
C15815
Health Care Activity
Monitoring for Recurrence
Surveillance
Ascend
Ascending
To travel upward.
Action
C61465
owl:Class
Ascend
C0205385
Activity
Ascend
Ascend
Fluorescence in situ Hybridization
A physical mapping approach that uses fluorescent tags to detect hybridization of probes within metaphase chromosomes or less condensed somatic interphase chromatin. This technique can be used for identification of chromosomal abnormalities and for gene mapping.
C17563
Laboratory Procedure
C0162789
FISH
owl:Class
Fluorescence in situ Hybridization
Fluorescence in situ Hybridization
Molecular Biology Research Technique
in situ Hybridization
Fluorescence in situ Hybridization
<def-source>CDISC</def-source><def-definition>A measurement of the hyaline casts present in a urine specimen.</def-definition>
Hyaline Cast Measurement
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Terminology
Hyaline Cast Measurement
Hyaline Cast Measurement
C74770
CDISC
owl:Class
CSHYAL
CDISC SDTM Laboratory Test Terminology by Name
Hyaline Casts
Urine Sediment Analysis Measurement
CL384404
Laboratory Procedure
CDISC SEND Terminology
Hyaline Cast Measurement
CDISC SDTM Laboratory Test Terminology by Code
The determination of the amount of hyaline casts present in a urine sample.
C15786
Therapeutic Procedure
Therapeutic or Preventive Procedure
Clinical Treatment
Clinical Treatment
owl:Class
CL000228
Clinical Treatment
Clinical Treatment
Actual observation and treatment of disease in patients (including experimental treatment) as distinct from theoretical or experimental work.
Health Education
Health education aimed at the general public
Public Health Education
CL000795
Public Health Education
owl:Class
C18975
Public Health Education
Educational Activity
Public Health Education
Portal Venous Phase Spiral CT
Portal Venous Phase Spiral CT
Portal Venous Phase Spiral CT
Portal Venous Phase Spiral CT
Diagnostic Procedure
CL009735
owl:Class
C19909
Phased Spiral CT
A type of computed tomography (CT) whereby images are taken during the portal venous phase post contrast medium injection. The portal venous phase is defined as the time period in which the contrast medium has passed the heart and the arterial blood vessels and has entered the hepatic portal vein. This type of CT does only apply to liver imaging.
CDISC SDTM Laboratory Test Terminology by Code
Blood Urea Nitrogen To Creatinine Ratio Measurement
BUN/Creatinine
CDISC SDTM Terminology
C0201922
The determination of the ratio of blood urea nitrogen compared to creatinine present in a sample. The measurement may be expressed as a ratio or percentage.
CDISC
CDISC SEND Terminology
Clinical Data Interchange Standards Consortium Terminology
Blood Urea Nitrogen To Creatinine Ratio Measurement
owl:Class
CDISC SDTM Laboratory Test Terminology by Name
Blood Urea Nitrogen To Creatinine Ratio Measurement
<def-definition>A relative measurement (ratio or percentage) of the blood urea nitrogen (BUN) to the creatinine in a blood specimen.</def-definition><def-source>CDISC</def-source>
Laboratory Procedure
BUNCREAT
C74753
Renal Function Test
Blood Urea Nitrogen To Creatinine Ratio Measurement
Daily Dose
Daily Dose
Conceptual Entity
Total Daily Dose
Daily Dose
owl:Class
A specified quantity of a therapeutic agent to which an individual can be exposed to or was exposed to, during a one-day period. In the clinical study protocol, the label and other documentation the type of daily dose must be specified.
DOSTOT
C70888
CL375779
Daily Dose
Dose
CDISC Observation Class Terminology
Laboratory Procedure
Multispectral Digital Microscopy
Multispectral Digital Microscopy
Microscopy
Multispectral Digital Microscopy
Multispectral Digital Microscopy
CL371218
owl:Class
C65169
C0237825
Rehabilitation
C15423
Psychosocial Rehabilitation
owl:Class
Programs, techniques, or processes of treatment by which individuals acquire psychological and social skills and attitudes which facilitate community interaction. (from PSY94)
Psychosocial Rehabilitation
Psychosocial Rehabilitation
Psychosocial Assessment and Care
Therapeutic or Preventive Procedure
Psychosocial Rehabilitation
C15705
Transurethral Resection
Excision
Transurethral Resection
Transurethral Resection
CL031926
Therapeutic or Preventive Procedure
transurethral resection
<def-source>NCI-GLOSS</def-source><def-definition>(TRANZ-yoo-REE-thral ree-SEK-shun) Surgery performed with a special instrument inserted through the urethra.</def-definition>
owl:Class
Transurethral Resection
TUR
Lymphadenectomy
CL343800
owl:Class
Regional Lymph Node Dissection
Surgical removal of the lymph nodes located in a particular anatomic region. This procedure is commonly performed as a component of cancer staging.
Therapeutic or Preventive Procedure
Regional Lymph Node Dissection
Regional Lymph Node Dissection
C48935
Regional Lymph Node Dissection
Diagnostic Procedure
Macrophage Inflammatory Protein 1 Alpha Measurement
C82023
Macrophage Inflammatory Protein 1 Alpha Measurement
Macrophage Inflammatory Protein 1 Alpha Measurement
owl:Class
Macrophage Inflammatory Protein 1 Alpha Measurement
The determination of the amount of macrophage inflammatory protein 1 alpha present in a sample.
Protein or Enzyme Type Measurement
Therapeutic Procedure
Supportive Care
Therapeutic or Preventive Procedure
Supportive care is that which helps the patient and their family to cope with cancer and treatment of it from pre-diagnosis, through the process of diagnosis and treatment, to cure, continuing illness or death and into bereavement. It helps the patient to maximize the benefits of treatment and to live as well as possible with the effects of the disease. Supportive therapy may provide a patient with friendship, encouragement, practical advice such as access to community resources or how to develop a more active social life, vocational counseling, suggestions for minimizing friction with family members, and, above all, hope that the life of the patient may be improved. In all situations, supportive therapy involves the teaching of such life skills as managing medication, learning to socialize, handling finances, and getting a job.
supportive care
Therapy, Supportive
Symptom Management
Supportive Care
Supportive Care
owl:Class
Supportive Therapy
C0344211
C15747
Supportive Care
CL323621
owl:Class
The Technology Development Study is one that includes development and mechanistic testing of new diagnostic and therapeutic methods.
Technology Development Study
Technology Development Study
Technology Development Study
C39526
Research Activity
Technology Development Study
Research Activity
Scar Excision
Scar Excision
Excision, Scar
Excision
Patient Problem Codes FDA CDRH
Scar Excision
C50827
FDA
Scar Excision
CL038518
Patient Code (Appendix B)
Health Care Activity
owl:Class
Contribution
Contributing
CL364078
The part played by somebody or something in bringing about an end or result.
Contribute
Activity
Contribution
Contribution
Action
owl:Class
Contribution
C61412
Pediatric Clinics and Services
CL000691
Pediatric Clinics and Services
owl:Class
C15833
Health Care Activity
Pediatric Clinics and Services
Pediatric Clinics and Services
Clinical Service
CL030495
Cancer Prevention
Breast Cancer Prevention
Anything, such as drug administration or lifestyle changes, designed to inhibit the onset of breast cancer.
owl:Class
Prevention of Breast Cancer
Breast Cancer Prevention
Breast Cancer Prevention
Therapeutic or Preventive Procedure
C15553
Breast Cancer Prevention
Protein or Enzyme Type Measurement
5 Prime Nucleotidase Measurement
5'-Ribonucleotide Phosphohydrolase
5 Prime Nucleotidase
CDISC SDTM Terminology
CDISC SEND Terminology
<def-definition>A measurement of the 5'-nucleotidase in a biological specimen</def-definition><def-source>CDISC</def-source>
CDISC SDTM Laboratory Test Terminology by Name
NCTD5P
Laboratory Procedure
owl:Class
5 Prime Nucleotidase Measurement
The determination of the amount of 5 prime nucleotidase present in a sample.
5 Prime Nucleotidase Measurement
C79437
Clinical Data Interchange Standards Consortium Terminology
5 Prime Nucleotidase Measurement
CDISC SDTM Laboratory Test Terminology by Code
Histologic Test
Histologic Test
Histologic Test
C49131
Histologic Test
Diagnostic Procedure
Histological Procedure
A diagnostic test used to examine and define microscopic tissue structure, composition, or etiology. The test results are often used by a clinician to diagnose disease or disordered function.
CL343663
owl:Class
Laboratory Procedure
Relaxation Technique
Therapeutic or Preventive Procedure
Relaxation Technique
Palliative Therapy
<def-source>MSH2002_06_01</def-source><def-definition>The use of muscular relaxation techniques in treatment.</def-definition>
relaxation techniques
Relaxation Technique
C0035029
owl:Class
Relaxation Technique
<def-source>NCI-GLOSS</def-source><def-definition>Methods used to reduce tension and anxiety, and control pain.</def-definition>
C28184
The determination of the number of Auer rods present in a sample.
<def-source>CDISC</def-source><def-definition>A measurement of the Auer rods (elongated needle structures that are found in the cytoplasm of leukemic blasts and are formed by clumps of azurophilic granular material) in a biological specimen.</def-definition>
CDISC SEND Terminology
Auer Rod Measurement
Auer Rod Measurement
Auer Rod Measurement
Auer Rod Measurement
CL384372
CDISC SDTM Laboratory Test Terminology by Code
Laboratory Procedure
owl:Class
AUERRODS
CDISC
Auer Rods
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Terminology
C74657
Clinical Data Interchange Standards Consortium Terminology
Hematology Test
Research Activity
clinical trial
Study
Clinical Trial
Clinical Trial
owl:Class
A research study that prospectively assigns human participants or groups of humans to one or more health-related interventions to evaluate the effects on health outcomes. Interventions include but are not restricted to drugs, cells and other biological products, surgical procedures, radiologic procedures, devices, behavioral treatments, process-of-care changes, and preventive care.
Clinical Trial
C0008976
Clinical Trials, Unspecified
Trial
Clinical Trials
Clinical Trial
<def-source>NCI-GLOSS</def-source><def-definition>A type of research study that tests how well new medical treatments or other interventions work in people. Such studies test new methods of screening, prevention, diagnosis, or treatment of a disease. The study may be carried out in a clinic or other medical facility.</def-definition>
C71104
Clinical Study
Encode
Encode
To assign a code to represent data.
Encode
Activity
Action
C80216
owl:Class
Encode
The determination of the ratio of total protein compared to creatinine present in a sample. The measurement may be expressed as a ratio or percentage.
Protein to Creatinine Ratio Measurement
CDISC SEND Terminology
Protein to Creatinine Ratio Measurement
Protein/Creatinine
Laboratory Procedure
owl:Class
CDISC SDTM Terminology
PROTCRT
Protein to Creatinine Ratio Measurement
Protein to Creatinine Ratio Measurement
C79463
<def-definition>A relative measurement (ratio or percentage) of the protein to creatinine in a biological specimen.</def-definition><def-source>CDISC</def-source>
Urine Protein Measurement
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Laboratory Test Terminology by Name
Clinical Data Interchange Standards Consortium Terminology
BMSCT
Bone Marrow Stem Cell Transplantation
C25437
Bone Marrow Transplantation
Therapeutic or Preventive Procedure
owl:Class
CL051947
Bone Marrow Stem Cell Transplantation
A procedure to replace diseased or pathologic bone marrow with transplanted healthy bone marrow stem cells.
Bone Marrow Stem Cell Transplantation
Bone Marrow Stem Cell Transplantation
owl:Class
Wash
Clean
Activity
CL370582
Cleanse with a cleaning agent, such as soap, and water.
Wash
Wash
Wash
C65077
Absolute Neutrophil Count
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Laboratory Test Terminology by Name
Absolute Neutrophil Count
C63321
C0948762
Absolute Neutrophil Count
Neutrophil Count
NEUT
CDISC
CDISC SEND Terminology
Clinical Data Interchange Standards Consortium Terminology
Neutrophils
ANC
<def-definition>A measurement of the neutrophils per unit of a biological specimen.</def-definition><def-source>CDISC</def-source>
Absolute Neutrophil Count
owl:Class
Laboratory Procedure
The real number of white blood cells (WBC) that are neutrophils. It is derived by multiplying the WBC count by the percent of neutrophils in the differential WBC count. The normal range for ANC is 1.5 to 8.0 (1,500 to 8,000/mm3).
CDISC SDTM Terminology
CL384348
C74626
CDISC SDTM Laboratory Test Terminology by Name
CDISC
Sickle Cells
SCKLCE
<def-source>CDISC</def-source><def-definition>A measurement of the sickle cells (sickle shaped red blood cells) in a biological specimen.</def-definition>
CDISC SDTM Terminology
Erythrocyte Count
The determination of the number of sickle cells present in a sample.
CDISC SEND Terminology
Laboratory Procedure
Clinical Data Interchange Standards Consortium Terminology
Sickle Cell Count
CDISC SDTM Laboratory Test Terminology by Code
Sickle Cell Count
Sickle Cell Count
owl:Class
Sickle Cell Count
C0542495
C61037
Serum Chemistry Measurement
owl:Class
Serum Triglyceride Measurement
Serum Triglyceride Measurement
A quantitative measurement of the amount of triglycerides present in a sample of serum.
Laboratory Procedure
Triglyceride Measurement
Serum Triglyceride Measurement
Serum Triglyceride Measurement
CL356254
C53350
Quantitative Concept
Delay Adjusted Incidence
Delay Adjusted Incidence
Population-Based Statistic
Delay Adjusted Incidence
Delay Adjusted Incidence
owl:Class
C1524035
Cytology Specimen Collection Procedure
Cytology Specimen Collection Procedure
owl:Class
C38113
Cytology Specimen Collection Procedure
Cytological Procedure
Laboratory Procedure
Cytology Specimen Collection Procedure
Cytologic Sampling
Laboratory Procedure
owl:Class
Microarray Technology
Microarray Analysis
Analysis using microarray technology (e.g., cDNA arrays to see gene expression or protein microarrays to profile the pattern of proteins).
C18477
Microarray-Based Analysis
Microarray Analysis
Molecular Analysis
CL385096
Gene Expression Profiling
Microarray Analysis
Microarray Analysis
CDISC SDTM Terminology
<def-definition>A measurement of the odd-shaped erythrocytes in a whole blood specimen.</def-definition><def-source>CDISC</def-source>
Laboratory Procedure
owl:Class
The determination of the number of poikilocytes present in a sample.
CDISC
Poikilocytes
Erythrocyte Count
C79602
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
POIKILO
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Name
Poikilocyte Measurement
Poikilocyte Measurement
Poikilocyte Measurement
Poikilocyte Measurement
Clinical Data Interchange Standards Consortium Terminology
C64818
Laboratory Procedure
CDISC SDTM Terminology
The determination of the number of atypical lymphocytes in a blood sample.
Lymphocytes Atypical
CL385241
CDISC SDTM Laboratory Test Terminology by Name
Atypical Lymphocyte Count
Atypical Lymphocyte Count
LYMAT
Atypical Lymphocyte Count
CDISC SEND Terminology
Lymphocyte Count
CDISC
Atypical Lymphocyte Count
CDISC SDTM Laboratory Test Terminology by Code
owl:Class
<def-definition>A measurement of the atypical lymphocytes per unit of a biological specimen.</def-definition><def-source>CDISC</def-source>
Procedure_Has_Partially_Excised_Anatomy only 'Vocal Cord'
Vocal Cord Biopsy
Diagnostic Procedure
C51908
owl:Class
Vocal Cord Biopsy
Vocal Cord Biopsy
Biopsy of Vocal Cord
Biopsy of Larynx
Vocal Cord Biopsy
CL355595
Removal of tissue from the vocal cords for microscopic examination.
Urological Surgical Procedure
Therapeutic or Preventive Procedure
C15334
Urologic Surgical Procedure
<def-source>MSH2001</def-source><def-definition>Surgery performed on the urinary tract or its parts in the male or female. For surgery of the male genitalia, UROLOGIC SURGICAL PROCEDURES, MALE is available.</def-definition>
Urologic Surgical Procedure
Urologic Surgery
C0038913
Urologic Surgical Procedure
Procedure_Has_Target_Anatomy only 'Urinary System'
Urogenital Surgical Procedure
Urinary Tract Surgery
owl:Class
Urologic Surgical Procedure
Immunoprecipitation
Laboratory Procedure
Antigen aggregation with antibody, in the right ratios, to cause precipitation.
owl:Class
Immunoprecipitation
C0021069
IP
Immunoprecipitation
Immunology Test
Immunoprecipitation
C16724
Therapeutic Procedure
radiotherapy
radiation therapy
Treatment of a disease by means of exposure of the target or the whole body to radiation. Radiation therapy is often used as part of curative therapy and occasionally as a component of palliative treatment for cancer. Other uses include total body irradiation prior to transplantation.
Therapeutic or Preventive Procedure
Cancer Radiotherapy
owl:Class
C0034618
Radiotherapeutics
Radiation Therapy
Radiation
Radiotherapy
irradiation
RT
Radiation Therapy
Therapy, Radiation
Radiation Therapy
C15313
Irradiation
Radiation Therapy
<def-source>NCI-GLOSS</def-source><def-definition>(RAY-dee-AY-shun) The use of high-energy radiation from x-rays, gamma rays, neutrons, and other sources to kill cancer cells and shrink tumors. Radiation may come from a machine outside the body (external-beam radiation therapy) or from materials called radioisotopes. Radioisotopes produce radiation and can be placed in or near the tumor or in the area near cancer cells. This type of radiation treatment is called internal radiation therapy, implant radiation, interstitial radiation, or brachytherapy. Systemic radiation therapy uses a radioactive substance, such as a radiolabeled monoclonal antibody, that circulates throughout the body.</def-definition>
Partial Pressure of Oxygen Measurement
owl:Class
Partial Pressure O2
Measures the pressure of oxygen dissolved in the blood and how well oxygen is able to move from the airspace of the lungs into the blood.
C0483414
Partial Pressure of Oxygen Measurement
Partial Pressure of Oxygen Measurement
Laboratory Procedure
Partial Pressure of Oxygen
PaO2
C71251
Diagnostic Procedure
Arterial Blood Gas Measurement
pO2
Partial Pressure of Oxygen Measurement
Preventive Intervention
Prevention of High-Risk Behavior
Prevention of High-Risk Behavior
Prevention of High-Risk Behavior
C15841
Therapeutic or Preventive Procedure
Behavioral Intervention
Prevention of High-Risk Behavior
owl:Class
1C2; Basic Sciences Research (includes vaccine and chemotherapy development); Behavioral Research; Prevention of high-risk behaviors (behavioral and pharmacologic interventions)
CL000751
Factor III Measurement
C81959
owl:Class
Factor III Measurement
Factor III Measurement
The determination of the amount of factor III present in a sample.
Factor III Measurement
Coagulation Study
owl:Class
Immunoglobulin A Measurement
The determination of the amount of immunoglobulin A present in a sample.
C81969
Immunoglobulin A Measurement
Immunoglobulin A Measurement
Immunoglobulin Measurement
Immunoglobulin A Measurement
Treatment Referral Center Protocol
Treatment Referral Center Protocol
Treatment Referral Center Protocol
Treatment Referral Center Protocol
C15539
CL030438
Treatment Regimen
owl:Class
Health Care Activity
owl:Class
Therapeutic or Preventive Procedure
CL353905
Excision of Uvula
Excision of Uvula
Excision of Uvula
Procedure_Has_Completely_Excised_Anatomy some Uvula
Excision of Uvula
Surgery involving the complete removal of the uvula.
Partial Pharyngectomy
Uvulectomy
C51746
Vaccine Testing
Vaccine Testing
CL053956
Vaccine Testing
Vaccine Research
Vaccine Testing
C26031
Research Activity
owl:Class
Non-Clinical Nanoparticle Application
Nanofabricate
Nanofabrication
Nanofabrication
A method of engineering that focuses on the design and manufacture of devices with dimensions measured in nanometers.
owl:Class
Nanofabrication
Activity
C62314
CL364915
Nanofabrication
Activity
Filtration
owl:Class
Action
C0016107
The process of passing a liquid or gas through a filter.
Fractionation, Filtration
Filtration
<def-source>MSH2001</def-source><def-definition>A process of separating particulate matter from a fluid, such as air or a liquid, by passing the fluid carrier through a medium that will not pass the particulates. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)</def-definition>
Filtration
C16583
Filtration
CDISC
randomized
Randomization
Clinical Data Interchange Standards Consortium Terminology
Randomized
C25196
Randomization
<def-source>NCI-GLOSS</def-source><def-definition>Describes an experiment or clinical trial in which animal or human subjects are assigned by chance to separate groups that compare different treatments.</def-definition>
Trial is Randomized
CDISC SDTM Trial Summary Parameter Terminology by Code
CDISC SDTM Terminology
CDISC SDTM Trial Summary Parameter Terminology by Name
owl:Class
Randomization
RANDOM
<def-source>CDISC</def-source><def-definition>The process of assigning trial subjects to treatment or control groups using an element of chance to determine the assignments in order to reduce bias. NOTE: Unequal randomization is used to allocate subjects into groups at a differential rate; for example, three subjects may be assigned to a treatment group for every one assigned to the control group. [ICH E6 1.48] See also balanced study. (CDISC glossary)</def-definition>
The allocation of individuals to groups by chance, especially in order to control the variables in an experiment.
C0034656
Health Care Activity
Clinical Trials Design
Randomization
Low-Dose Treatment
Therapeutic Procedure
owl:Class
C49341
CL355223
A reduced quantity of a therapeutic agent prescribed to be taken at one time or at stated intervals.
Low-Dose Treatment
Conceptual Entity
Low-Dose Treatment
Low-Dose Treatment
Low-Dose
Healthcare Activity
The systemic measurement of the quality of health care that includes a broad set of perfomance measures such as the quality of services and the outcomes analysis for particular diseases and conditions, mortality and morbidity, patient safety, data on maternal and child health, as well as evaluation of quality of diagnosis, care excessability, implementation of proven evidence-based practices, quality of reporting systems for errors and adverse events, reliability and excessability of health and health care-related information, and health care organizations infrastructure.
Quality of Health Care Assessment
C0086887
owl:Class
Health Care Activity
Quality of Health Care Assessment
C41392
Quality of Health Care Assessment
Quality of Health Care Assessment
Antiangiogenesis Therapy
Antiangiogenesis Therapy
Antiangiogenesis Therapy
Therapeutic or Preventive Procedure
owl:Class
C15568
Anti-Angiogenesis
Growth Factor Antagonist Therapy
Antiangiogenesis
antiangiogenesis
Antiangiogenesis Therapy
<def-source>NCI-GLOSS</def-source><def-definition>Prevention of the growth of new blood vessels.</def-definition>
A therapeutic regimen that uses synthetic compounds or natural substances to prevent the development of new blood vessels.
C0281318
Angiogenesis Inhibition
Procedure_Has_Target_Anatomy only Colon
Colonoscopy
owl:Class
C16450
Diagnostic Procedure
Colonoscopy
Endoscopic examination of the luminal surface of the colon.
Colonoscopy
Gastrointestinal Endoscopy
colonoscopy
<def-source>NCI-GLOSS</def-source><def-definition>(ko-lun-AHS-ko-pee) An examination of the inside of the colon using a thin, lighted tube (called a colonoscope) inserted into the rectum. If abnormal areas are seen, tissue can be removed and examined under a microscope to determine whether disease is present.</def-definition>
C0009378
Colonoscopy
Therapeutic or Preventive Procedure
Therapeutic or Preventive Procedure
Transfer Factor Therapy
owl:Class
Transfer Factor Therapy
Cytokine Therapy
Transfer Factor Therapy
Transfer Factor Therapy
CL028795
therapy, transfer factor
C15435
Consolidation Therapy
Consolidation Therapy
owl:Class
consolidation therapy
Consolidation Therapy
<def-source>NCI-GLOSS</def-source><def-definition>Chemotherapy treatments given after induction chemotherapy to further reduce the number of cancer cells.</def-definition>
C15679
Consolidation Therapy
Chemotherapy
CL031814
Therapeutic or Preventive Procedure
C16071
Pharmacobehavioral Research
Behavioral Research
Pharmacobehavioral Research
Evaluates new pharmacologic agents and methods of behavior modification.
Pharmacobehavioral Research
Pharmacobehavioral Research
Research Activity
CL008230
owl:Class
C0030548
Total Parenteral Nutrition
C29484
TPN
Total Parenteral Nutrition
Therapeutic or Preventive Procedure
Total Parenteral Nutrition
owl:Class
Total parenteral nutrition formulated for intravenous administration in patients who cannot eat or cannot get enough nutrients from the foods they eat. It is a liquid mixture of proteins, carbohydrates, fats, vitamins, minerals and other nutrients.
Nutritional Intervention
Total Parenteral Nutrition
Isolated Perfusion
Isolated Limb Perfusion
Limb Perfusion
owl:Class
Isolated Limb Perfusion
C15393
<def-source>NCI-GLOSS</def-source><def-definition>(per-FYOO-zhun) A technique that may be used to deliver anticancer drugs directly to an arm or leg. The flow of blood to and from the limb is temporarily stopped with a tourniquet, and anticancer drugs are put directly into the blood of the limb. This allows the person to receive a high dose of drugs in the area where the cancer occurred. Also called isolated limb perfusion.</def-definition>
Isolated Limb Perfusion
limb perfusion
isolated limb perfusion
C0396670
Isolated Limb Perfusion
Therapeutic or Preventive Procedure
CL331985
Human Subject Research
Minimal Risk Study
Minimal Risk Study
Research Activity
Minimal Risk Study
The clinical research that involves testing an approved drug with a well-known adverse event profile, and includes physiologic measurements and procedures that carry little risk to the participant.
Minimal Risk Study
owl:Class
C41386
Quantitative Concept
Opportunistic Sampling
Opportunistic Sampling
owl:Class
Opportunistic Sampling
Matched Sampling
Opportunistic Sampling
C71512
CL378053
Macrophage Inflammatory Protein 1 Beta Measurement
Protein or Enzyme Type Measurement
Macrophage Inflammatory Protein 1 Beta Measurement
owl:Class
C82024
Macrophage Inflammatory Protein 1 Beta Measurement
Macrophage Inflammatory Protein 1 Beta Measurement
The determination of the amount of macrophage inflammatory protein 1 beta present in a sample.
C15941
Research Activity
CL003270
Collaborative and interdisciplinary genetic epidemiology investigations designed to identify and evaluate the interactions of genetic and epidemiologic risk factors leading to cancer susceptibility in individuals, families and populations, and factors influencing the rate of increase with age in cancer susceptibility. Emphasis on multi-site, cooperative research by multi- disciplinary teams of investigators wishing to collaborate within the common theme of the genetic epidemiology of cancer. Particular emphasis is placed on encouraging interdisciplinary, population-based research focusing on the etiologic mechanisms underlying the interaction of genetic and epidemiologic risk factors for cancer susceptibility. The effect on cancer susceptibility of age-related changes over the lifespan, and the genetic factors leading to older age at onset of cancer are also of interest.
Interdisciplinary Studies in the Genetic Epidemiology of Cancer
owl:Class
Interdisciplinary Studies in the Genetic Epidemiology of Cancer
Interdisciplinary Studies in the Genetic Epidemiology of Cancer
Interdisciplinary Studies in the Genetic Epidemiology of Cancer
Cancer Research
Individual Case Safety Report Terminology
Replacement
Governmental or Regulatory Activity
Replacement
C0559956
The act of removing one thing and putting another thing in its place.
Replaced
Replacement
C53610
Type Of Remedial Action ICSR Terminology
Remedial Action
FDA
owl:Class
Replacement
CDISC SDTM Laboratory Test Terminology by Name
Iron Binding Capacity
C1283048
CDISC SEND Terminology
CDISC
Total Iron Binding Capacity
Total Iron Binding Capacity
The determination of the saturation of iron binding sites on serum transferrin proteins.
IBCT
CDISC SDTM Terminology
Total Iron Binding Capacity
Clinical Data Interchange Standards Consortium Terminology
<def-source>CDISC</def-source><def-definition>A measurement of the amount of iron needed to fully saturate the transferrin in a serum specimen.</def-definition>
owl:Class
C74718
CDISC SDTM Laboratory Test Terminology by Code
Total Iron Binding Capacity
Laboratory Procedure
Parenteral Infusion Procedure
Parenteral Infusion Procedure
Therapeutic or Preventive Procedure
C21088
Intravenous Infusion
IV Infusion
Infusion Procedure
Parenteral Infusion Procedure
Parenteral Infusion Procedure
Administration of medications or nutrients directly into the venous system.
C0021441
Parenteral Infusion
owl:Class
No Repeatitions
Activity
C67011
No Repeats
Instruction Imperative
No Repeats
Non Repetatur
No Repeats
No Repeats
non rep.
owl:Class
CL371469
Bone Scan
Diagnostic Procedure
C0203668
Bone Scan
A nuclear imaging method used to evaluate pathological bone metabolism.
Bone Scan
Bone Scan
C17646
<def-source>NCI-GLOSS</def-source><def-definition>A technique to create images of bones on a computer screen or on film. A small amount of radioactive material is injected into a blood vessel and travels through the bloodstream; it collects in the bones and is detected by a scanner.</def-definition>
Radionuclide Imaging
bone scan
owl:Class
Bone Marrow Donation
Therapy Preparation
Health Care Activity
Bone Marrow Donation
Bone Marrow Donation
C64258
Bone Marrow Donation
Traditionally, minor surgery to draw marrow from the hipbones followed by collection of the stems cells from the donated marrow. Today the most common way of collecting the stem cells is by filtering them directly from the blood. Although this procedure is technically called peripheral blood stem cell donation, it is still commonly referred to as bone marrow donation.
owl:Class
C1305211
Staining of Sputum for Pneumocystis
Staining of Sputum for Pneumocystis
A simple and noninvasive procedure for Pneumocystis carinii pneumonia (PCP) diagnosis, in which the specimen used is induced sputum. The specimen is stained with either Giemsa, silver stain or toluidine blue. Alternatively, an indirect immunofluorescent stain using monoclonal antibodies can be used.
Staining of Sputum for Pneumocystis
Staining of Sputum for Pneumocystis
Laboratory Procedure
Staining of Sputum for Pneumocystis
C23039
owl:Class
Special Histology Staining Method
C0523198
C29900
Research Activity
Organism Modification
Mechanical Stimulation
Mechanical Stimulation
Mechanical Stimulation
C1285354
owl:Class
Mechanical Stimulation
Annual Percent Change
Measures the change in rate over time by taking the number of occurrences for the current year, subtracting the number of occurrences for the previous year, dividing the difference by the number of occurrences for the previous year, and then multiply the dividend by one hundred.
CL356603
Annual Percent Change
Trend in Rates
Annual Percent Change
owl:Class
Quantitative Concept
Annual Percent Change
C53355
<def-source>NCI-GLOSS</def-source><def-definition>A type of clinical trial in which only the doctor knows whether a patient is taking the standard treatment or the new treatment being tested. This helps prevent bias in treatment studies.</def-definition>
Single Blind Study
<def-source>CDISC</def-source><def-definition>A study in which one party, either the investigator or the subject, does not know which medication or placebo is administered to the subject; also called singlemasked study. (CDISC glossary)</def-definition>
Single Blind Study
CDISC
Single Blind Study
Clinical Data Interchange Standards Consortium Terminology
single blind study
Trial Blinding Schema
SINGLE BLIND
CDISC SDTM Trial Blinding Schema Terminology
Single Blind Study
C28233
A type of study that stipulates the subject to be unaware of the drug or treatment assignment.
CDISC SDTM Terminology
C0242570
owl:Class
Research Activity
Obtain
owl:Class
Instruction Imperative
C52349
Action
Activity
Obtain
To come into possession of something.
C1301820
Obtain
Obtain
Obtained
Pain Therapy
Intravenous Patient-Controlled Analgesia
Intravenous Patient-Controlled Analgesia
Intravenous Patient-Controlled Analgesia
C0078944
Therapeutic or Preventive Procedure
C21060
PCA
patient-controlled analgesia
A method of intravenous narcotic analgesic delivery that uses a pump or similar delivery system that allows the patient, or in the absence of the patient's ability to do so the patient's nurse or family members, to administer predetermined doses of analgesic as needed to maintain adequate pain control. This method allows the patient and/or family to have increased autonomy. Further, research has shown improved pain control and reductions in narcotics necessary to maintain pain control to be associated with this delivery method.
Intravenous Patient-Controlled Analgesia
Patient-Controlled Analgesia
owl:Class
<def-source>MSH2002_06_01</def-source><def-definition>Relief of pain, without loss of consciousness, through an analgesic agent administered by the patient. It has been used successfully to control postoperative pain, during labor, after burns, and in terminal care. The choice of agent, dose, and lockout interval greatly influence effectiveness. The potential for overdose can be minimized by combining small bolus doses with a mandatory interval between successive doses (lockout interval).</def-definition>
IV PCA
<def-source>NCI-GLOSS</def-source><def-definition>PCA. A method in which the patient controls the amount of pain medicine that is used. When pain relief is needed, the person can receive a preset dose of pain medicine by pressing a button on a computerized pump that is connected to a small tube in the body.</def-definition>
<def-source>NCI-GLOSS</def-source><def-definition>The destruction of bone marrow using radiation or drugs.</def-definition>
owl:Class
bone marrow ablation
CL030616
Therapeutic Bone Marrow Suppression
Bone Marrow Ablation
The destruction of bone marrow using radiation or drugs.
Bone Marrow Ablation
Bone Marrow Ablation
Therapeutic or Preventive Procedure
Bone Marrow Ablation
Ablation Therapy
C15569
Descending
Descend
Descend
Action
Descend
C61573
To travel downward.
C0205386
owl:Class
Descend
Activity
Average of Value Derivation Technique
Statistical Imputation
Average of Value Derivation Technique
owl:Class
Average of Value Derivation Technique
Average of Value Derivation Technique
Quantitative Concept
C81209
The substitution of missing data with a value that represents the average of a group of specified values.
CDISC
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Code
owl:Class
C0369738
CDISC SDTM Laboratory Test Terminology by Name
The determination of the number of band neutrophils in a blood sample.
Neutrophil Count
Neutrophil Band Form Count
Neutrophil Band Form Count
Neutrophils Band Form
<def-definition>A measurement of the banded neutrophils per unit of a biological specimen.</def-definition><def-source>CDISC</def-source>
Neutrophil Band Form Count
C64830
Clinical Data Interchange Standards Consortium Terminology
NEUTB
CDISC SEND Terminology
CDISC SDTM Terminology
Neutrophil Band Form Count
CDISC
C64858
Total Protein Measurement
Protein or Enzyme Type Measurement
CDISC SEND Terminology
A quantitative measurement of the amount of total protein present in a sample.
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
<def-source>CDISC</def-source><def-definition>A measurement of a group of complex organic macromolecules composed of one or more alpha-L-amino acid chains in a biological specimen.</def-definition>
Protein
PROT
Total Protein Measurement
Clinical Data Interchange Standards Consortium Terminology
Total Protein Measurement
C0555903
CDISC SDTM Laboratory Test Terminology by Code
Total Protein Measurement
owl:Class
CDISC SDTM Terminology
Laboratory Procedure
<def-definition>A measurement of the reactive lymphocytes (lymphocytes which have become large due to an antigen reaction) in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Laboratory Test Terminology by Code
C74629
Reactive Lymphocyte Count Measurement
Reactive Lymphocytes
Reactive Lymphocyte Count Measurement
Reactive Lymphocyte Count Measurement
CDISC SDTM Laboratory Test Terminology by Name
The determination of the number of reactive lymphocytes present in a blood sample.
Atypical Lymphocyte Count
Clinical Data Interchange Standards Consortium
Lymphocyte Count
CDISC SEND Terminology
owl:Class
LYMRCT
CDISC SDTM Terminology
Reactive Lymphocyte Count Measurement
CL384344
liver cancer, screening for
hepatocellular cancer, screening for
owl:Class
screening for liver cancer
Screening for Hepatocellular Cancer
CL032271
Screening for Hepatocellular Cancer
Screening for Hepatocellular Cancer
C15741
Diagnostic Procedure
Screening for Hepatocellular Cancer
Cancer Screening
Minority-Based Community Clinical Oncology Program
A system designed to ensure adequate representation of minority groups in clinical trials.
CL008238
owl:Class
Minority-Based Community Clinical Oncology Program
Minority-Based Community Clinical Oncology Program
C16074
Minority-Based Community Clinical Oncology Program
Community Clinical Oncology Program
Research Activity
Bone Marrow Flow Cytometry
Flow Cytometry
Bone Marrow Flow Cytometry
owl:Class
Bone Marrow Cytometry
CL322417
Bone Marrow Flow Cytometry
Hematology Test
Flow cytometry using cells derived from a bone marrow sample.
Laboratory Procedure
Bone Marrow Flow Cytometry
C38063
Molecular Epidemiology of Prostate Cancer
C19257
The objective is to examine the role of genes that regulate the metabolism of environmental carcinogens in prostate cancer etiology. These genes include cytochromes P450 (e.g. CYP1A1, CYP2D6, and CYP2E1) and the mu or theta classes of the glutathione-S-transferases. Three specific aims are proposed to accomplish this objective. In Specific Aim l, the relationship of each of the candidate genes and the occurrence or age of onset of prostate cancer will be examined. The relationship between multiple candidate genes and the occurrence or age of onset of prostate cancer will be examined in Specific Aim 2. The interactions of multiple candidate genes, environments, and exposures will be examined in Specific Aim 3. (from EGP Research Programs, PI: Timothy R. Rebbeck, University of Pennsylvania, R29_ES_08031_03)
Research Activity
owl:Class
Cancer Research
Molecular Epidemiology of Prostate Cancer
CL003271
Molecular Epidemiology of Prostate Cancer
Molecular Epidemiology of Prostate Cancer
Surgical removal of part of the uterus.
Hysterectomy
owl:Class
C40961
Therapeutic or Preventive Procedure
Partial Hysterectomy
Partial Hysterectomy
Procedure_Has_Partially_Excised_Anatomy only 'Corpus Uteri'
Partial Hysterectomy
Partial Hysterectomy
C1270947
Diagnostic Procedure
Diagnostic Bronchoscopy
Diagnostic Bronchoscopy
Diagnostic Bronchoscopy
Diagnostic Bronchoscopy
C64952
Diagnostic Endoscopic Procedure
owl:Class
C0585632
Bronchoscopy
Social Behavior
C0023676
C16795
A manner of living that reflects the person's values and attitudes.
Lifestyle
Lifestyle
owl:Class
Behavior
Lifestyle
Lifestyle
Prior Adjuvant Chemotherapy
CL030548
Prior Adjuvant Chemotherapy
Prior Biologic Therapy
Prior Adjuvant Chemotherapy
Prior Adjuvant Chemotherapy
Clinical Attribute
C15564
owl:Class
Metronomic Chemotherapy
Metronomic Chemotherapy
owl:Class
Therapeutic or Preventive Procedure
Metronomic Chemotherapy
CL365068
Chemotherapy
C62453
A chemotherapy regimen consisting of repetitive, low doses of chemotherapy drugs that are designed to minimize toxicity. This therapeutic treatment targets the endothelium or stroma as opposed to targeting the tumor or cancerous region.
Metronomic Chemotherapy
Pulmonary Valve Replacement
Pulmonic Valve Replacement
owl:Class
Procedure_Has_Completely_Excised_Anatomy only 'Pulmonary Valve'
Cardiac Therapeutic Procedure
Cardiovascular Surgical Procedure
Surgery performed with the purpose of replacing a degenerated, calcified, malformed, dysfunctional, etc. pulmonary valve with bioprosthetic, homograft or autograft valve.
Pulmonary Valve Replacement
C0190129
Valve Of Pulmonary Trunk Replacement
Pulmonary Valve Replacement
C50817
Therapeutic or Preventive Procedure
Pulmonary Valve Replacement
owl:Class
Radioisotopic Labeling
Research Technique
Radioisotopic Labeling
CL383738
Radioisotopic Labeling
Radioisotopic Labeling
Laboratory Procedure
Radiolabeling
A laboratory procedure that results in the incorporation of a radioactive isotope into a molecule of interest.
This procedure allows the labeled product to be tracked in laboratory assays.
C73481
C48292
Curation
Action
To organize and oversee.
owl:Class
Curate
Curation
Curation
CL341523
Activity
Curation
Therapeutic Clinical Trial
Therapeutic Clinical Trial
owl:Class
Research Activity
Therapeutic Clinical Trial
Clinical Trials, Therapy
A clinical study that involves administering of exposure to the agent/agents to subjects with particular disease to elucidate the most appropriate treatment for a specific medical condition, or to prolong or improve the patient's life.
Trial Type
CL323631
C39536
Therapeutic Trials
Therapeutic Clinical Trial
Case-Control Study
<def-source>MSH2001</def-source><def-definition>Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.</def-definition>
Study Design
Research Activity
owl:Class
C15197
C0007328
Case-Control Study
Case-Control Study
Case-Control Study
owl:Class
C16680
Histological Procedure
Histological Technique
Histological Techniques
Histological Procedure
Histological Procedure
Anatomic Pathology Procedure
Histologic Procedure
C0019637
Laboratory Procedure
Technique or procedure used for the study of the microanatomy of tissues and their cellular structure; usually involves microscopic examination of tissue slices.
Histological Procedure
CL355720
owl:Class
Activity
Graduation
Action
Graduation
C52581
Graduation
Conferral or receipt of an academic degree or diploma marking the completion of a defined set of coursework.
Graduation
Epididymectomy
Procedure_Has_Excised_Anatomy only Epididymis
CL354547
Epididymectomy
Urogenital Surgical Procedure
Epididymectomy
C51493
owl:Class
Epididymectomy
Therapeutic or Preventive Procedure
DOSADJ
Activity
C82495
An indication or description of a change in dosage.
Dose Adjustment
Adjustment
CDISC Observation Class Terminology
owl:Class
Dose Adjustment
Dose Adjustment
Dose Adjustment
Therapeutic or Preventive Procedure
Curative Surgery
Curative Surgery
CL322408
owl:Class
Curative Surgery
C38047
Surgical Procedure
Surgery which cures disease.
Curative Surgery
Therapeutic or Preventive Procedure
Cardiovascular Complications Management
Cardiovascular Complications Management
Cardiovascular Complications Management
Cardiovascular Complications Management
C64976
owl:Class
CL370133
Supportive Care
Therapeutic or Preventive Procedure
Ultrasonic Surgical Aspiration
owl:Class
Ultrasonic Surgical Aspiration
Aspiration
C64863
Diagnostic Procedure
A procedure in which tissue is broken up into small fragments by ultrasound and then removed by aspiration.
Ultrasonic Surgical Aspiration
CL370361
Ultrasonic Surgical Aspiration
owl:Class
Multivariate Normal Distribution
CL355760
Multivariate Normal Distribution
Normal Distribution
Quantitative Concept
C53218
A normal distribution which models more than one variable of interest. The parameters of the multivariate normal distribution include the mean and variance of each individual variable and the correlations between variables.
Multivariate Normal Distribution
Multivariate Normal Distribution
Activity
C65061
Push
Push
The act of applying force in order to move something away.
Push
Pushing
CL370577
Instruction Imperative
Push
owl:Class
Targeted Molecular Therapy
C76243
Targeted Molecular Therapy
Targeted Molecular Therapy
Cancer therapies designed to act upon specific molecules in metabolic pathways or processes involved in carcinogenesis, tumor growth, or tumor spread.
CL386389
Therapeutic or Preventive Procedure
owl:Class
Therapeutic Procedure
Targeted Molecular Therapy
Proportional Stratified Sampling
Probability Proportional to Size Sampling
Probability Proportional to Size Sampling
owl:Class
C53198
CL356342
Probability Proportional to Size Sampling
Probability Proportional to Size Sampling
Quantitative Concept
Abdominal Hysterectomy
C51660
Procedure_Has_Target_Anatomy only 'Abdominal Cavity'
owl:Class
Therapeutic or Preventive Procedure
Abdominal Hysterectomy
Abdominal Hysterectomy
Abdominal Hysterectomy
Hysterectomy
C0404077
Surgical removal of part or all of the uterus via an abdominal approach.
3,4-Methylenedioxymethamphetamine Measurement
Amphetamine Drug Class Measurement
C75359
Methylenedioxymethamphetamine Measurement
C1266617
3,4-Methylenedioxymethamphetamine Measurement
The determination of the amount of 3,4-methylenedioxymethamphetamine (MDMA) present in a sample.
MDMA Measurement
3,4-Methylenedioxymethamphetamine Measurement
owl:Class
3,4-Methylenedioxymethamphetamine Measurement
Laboratory Procedure
A quantitative measurement of the gas carbon dioxide present in a sample.
<def-source>CDISC</def-source><def-definition>A measurement of the carbon dioxide gas in a biological specimen.</def-definition>
Chemistry Test
CDISC SDTM Laboratory Test Terminology by Name
owl:Class
Clinical Data Interchange Standards Consortium Terminology
Carbon Dioxide
CDISC SDTM Terminology
Carbon Dioxide Measurement
CDISC SEND Terminology
CDISC
CDISC SDTM Laboratory Test Terminology by Code
CO2
C0201930
C64545
Carbon Dioxide Measurement
Carbon Dioxide Measurement
Carbon Dioxide Measurement
Laboratory Procedure
Molecular Profiling
owl:Class
Determining which genes are active and inactive and the level of specific proteins that are present in a particular tumor. (Bypass Budget)
Molecular Fingerprinting of Tumor
C19967
Molecular Fingerprinting of Tumor
Laboratory Procedure
Molecular Fingerprinting of Tumor
Molecular Fingerprinting of Tumor
CL014013
Corticotropin Releasing Hormone
Corticotropin Releasing Hormone Measurement
CDISC SDTM Laboratory Test Terminology by Name
Hormone Measurement
Laboratory Procedure
Corticotropin Releasing Hormone Measurement
C74851
<def-definition>A measurement of the corticotropin releasing hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
Corticotropin Releasing Hormone Measurement
C1295117
Corticotropin Releasing Hormone Measurement
Clinical Data Interchange Standards Consortium Terminology
CRH
The determination of the amount of corticotropin releasing hormone present in a sample.
owl:Class
Corticotropin Releasing Factor
CDISC SDTM Laboratory Test Terminology by Code
CDISC SEND Terminology
CDISC SDTM Terminology
owl:Class
CDISC SEND Terminology
CRTRONE
Corticosterone Measurement
Laboratory Procedure
C79434
Corticosterone Measurement
Corticosterone Measurement
Hormone Measurement
<def-definition>A measurement of corticosterone in a biological specimen.</def-definition><def-source>CDISC</def-source>
The determination of the amount of corticosterone present in a sample.
CDISC SDTM Laboratory Test Terminology by Name
Corticosterone Measurement
Clinical Data Interchange Standards Consortium Terminology
Corticosterone
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Terminology
Synaptophysin
Immunohistochemistry staining technique.
Laboratory Procedure
Synaptophysin Staining Method
Synaptophysin Staining Method
Synaptophysin Staining Method
Synaptophysin Staining Method
C23029
owl:Class
Synaptophysin Staining Method
SYNP
Special Histology Staining Method
This is an immunohistochemical technique utilizing antibody to synaptophysin, an integral membrane glycoprotein present in presynaptic vesicles in neurons. The antibody labels neuroendocrine cells and neurons of the brain, spinal cord and retina. Used to detect neuroendrocrine neoplasms including neuroblastomas, ganglioneuroblastomas, ganglioneuromas, pheochromocytomas, chromaffin, and non-chromaffin paragangliomas.
C0085255
Background Correction Method
owl:Class
CL369295
MAS Background Correction Method
MAS Background Correction Method
C64237
Activity
This is an implementation of the Affymetrix (2002) MAS algorithm for background correction, which divides each chip into regions, uses a threshold to identify a 'background' level of expression, and subtracts this from both MM and PM probes.
MAS Background Correction Method
MAS Background Correction Method
owl:Class
Nutrition, Fiber
Nutrition, Fiber
Nutrition, Fiber
Research Activity
Role of dietary fiber in cancer causation or prevention and in general health.
C15225
Nutrition, Fiber
C0012173
Nutrition, Dietary Components
Health Care Activity
Birth Method of Delivery
Birth Method of Delivery
Birth Method of Delivery
Newborn Screening
C81179
owl:Class
Description of the method by which a fetus is delivered.
Birth Method of Delivery
Technique
Panel Study
owl:Class
Panel Study
Study Design
C0681848
C53311
Research Activity
Panel Study
Panel Study
Procedure_May_Have_Excised_Anatomy some 'Left Lobe of the Liver'
Lobectomy of Liver
Lobectomy of Liver
Lobectomy of Liver
Procedure_May_Have_Excised_Anatomy some 'Right Lobe of the Liver'
Lobectomy of Liver
Lobectomy
Surgical removal of a lobe of the liver.
C51555
Therapeutic or Preventive Procedure
owl:Class
CL354085
Partial Hepatectomy
Animal Testing
Testing
CL008659
Animal Testing
C16087
The use of animals for testing the safety and efficacy of drugs or treatments.
owl:Class
Animal Testing
Animal Testing
Research Activity
RPLND
Therapeutic or Preventive Procedure
CL051237
Retroperitoneal Lymph Node Dissection
Diagnostic Procedure
Retroperitoneal Lymph Node Dissection
owl:Class
Retroperitoneal Lymph Node Dissection
C48184
Retroperitoneal Lymph Node Dissection
The surgical removal of retroperitoneal lymph nodes from the abdominal cavity. The surgery is a therapeutic treatment for testicular cancer, performed after (orchiectomy) or testicular removal. The surgery is recommended for men who are at an increased risk of metastasis, or who decline other treatment options such as radiation or chemotherapy.
Regional Lymph Node Dissection
Cancer Prevention
NIH Emphasis Area -- The term "prevention" refers to prophylactic and preventative efforts to achieve a significant reduction in cancer incidence, cancer mortality, and cancer morbidity. "Primary prevention" involves efforts to directly prevent and/or inhibit malignant transformation; to identify, characterize, and manipulate factors that might be effective in achieving that inhibition; and attempts to promote preventative measures, such as appropriate training of scientists and clinicians. Prevention and intervention efforts are biologic activities aimed at the cell - at the genetic and cellular changes that result in the transformation process and that define cancer development
C15777
Cancer Prevention, Primary
owl:Class
Primary Prevention
Cancer Prevention, Primary
Cancer Prevention, Primary
CL000154
Cancer Prevention, Primary
Therapeutic or Preventive Procedure
CL005630
Laboratory Procedure
C19590
WGA
Polymerase Chain Reaction
Whole Genome Amplification
Whole Genome PCR
Whole Genome Amplification
owl:Class
Whole Genome Amplification
Whole Genome Amplification
A PCR technique designed to amplify a limited genomic DNA sample so as to generate a new sample that is indistinguishable from the original but with a higher DNA concentration.
Molecular Biology Research Technique
Follow Directions
Follow Directions
Activity
CL370432
Follow
Follow Directions
owl:Class
Follow Directions
C64951
C80199
Neopterin Measurement
owl:Class
Neopterin Measurement
Laboratory Procedure
Neopterin Measurement
The determination of the amount of neopterin present in a sample.
Immunology Test
Neopterin Measurement
Linkage Disequilibrium Mapping
Linkage disequilibrium (LD) mapping is a procedure for determining the non-random association of alleles at two or more loci on a chromosome. It is based on the premise that regions adjacent to a gene of interest are transmitted through the generations along with that gene and can be identified by the specific pattern of markers (haplotypes) that they contain, so that detection of haplotypes that are shared more frequently among groups of individuals recruited for a disease or trait can be used to locate specific genes. Linkage-disequilibrium (LD) mapping is useful in identifying genes involved in complex diseases.
Linkage Disequilibrium Mapping
Laboratory Procedure
owl:Class
CL008157
Linkage Disequilibrium Mapping
Gene Mapping
C19647
Molecular Biology Research Technique
Linkage Disequilibrium Mapping
Plastic Surgery Procedure
Surgical Procedure by Method
C0677616
<def-source>NCI-GLOSS</def-source><def-definition>An operation that restores or improves the appearance of body structures.</def-definition>
Plastic Surgery Procedure
C39766
Therapeutic or Preventive Procedure
plastic surgery
owl:Class
Plastic Surgery Procedure
Plastic Surgery Procedure
Metabolic Abnormality Assessment
Metabolic Abnormality Assessment
Metabolism Studies
Physiologic Testing
Metabolic Studies
C17870
Metabolic Abnormality Assessment
owl:Class
Abnormal Assessment of Metabolism
Metabolic Assessment, Abnormality
Laboratory Procedure
Metabolic Abnormality Assessment
CL030094
LAK cell therapy
Lymphokine-Activated Killer Cell Therapy
Lymphokine-Activated Killer Cell Therapy
C15412
C0199976
Lymphokine-Activated Killer Cell Therapy
owl:Class
Lymphokine-Activated Killer Cell Therapy
Therapeutic or Preventive Procedure
Adoptive Immunotherapy
Surveillance Program
Surveillance Program
Cancer Control Research
C16050
Surveillance Program
Research Activity
CL007021
Surveillance Program
owl:Class
Karyometry
C82399
Karyometry
Digital Texture Analysis
Karyometry
Laboratory Procedure
Diagnostic Procedure
Video-microscopy procedure for the analysis of the nuclear chromatin organization status in neoplastic lesions and the detection of nuclear subpopulations on hematoxylin-eosin stained sections.
Light Microscopy
owl:Class
Karyometry
Computer Modeling
The computer simulation of chemical structures or processes; allows for the exploration, visualization, and manipulation of molecular structures and properties.
C0600115
Molecular Modeling
C18148
owl:Class
Molecular Modeling
Molecular Modeling
Protein/Amino Acid Biochemistry, Molecular Modeling
Nucleic Acid Biochemistry, Molecular Modeling
Molecular Modeling
Activity
Therapeutic Procedure
Salvage Therapy
<def-source>NCI-GLOSS</def-source><def-definition>Treatment that is given after the cancer has not responded to other treatments.</def-definition>
Salvage Therapy
Therapeutic or Preventive Procedure
salvage therapy
C0085405
Salvage Therapy
C15359
owl:Class
Salvage Therapy
Clinical Attribute
Prior Biologic Therapy
Prior Interferon Therapy
Prior Interferon Therapy
CL029118
Prior Interferon Therapy
Prior Interferon Therapy
C15453
owl:Class
Remission Induction Therapy
C15746
Remission Induction Therapy
CL032287
Remission Induction Therapy
<def-source>NCI-GLOSS</def-source><def-definition>The initial chemotherapy a person receives to bring about a remission.</def-definition>
Remission Induction Therapy
Therapeutic or Preventive Procedure
Chemotherapy
remission induction therapy
owl:Class
Prospective Cohort Study
CL355794
<def-source>NCI-GLOSS</def-source><def-definition>A research study that follows over time groups of individuals who are alike in many ways but differ by a certain characteristic (for example, female nurses who smoke and those who do not smoke) and compares them for a particular outcome (such as lung cancer).</def-definition>
C53308
Prospective Cohort Study
Research Activity
owl:Class
Cohort Study
Prospective Cohort Study
Prospective Cohort Study
prospective cohort study
Health Care Activity
owl:Class
Risk Factor Service
Risk Factor Service
Risk Factor Service
C15934
Clinical Service
Risk Factor Service
CL003231
Enzyme Immunoassay
Any of several immunoassay methods that use an enzyme covalently linked to an antigen or antibody as a label; the most common types are enzyme-linked immunosorbent assay (ELISA) and enzyme-multiplied immunoassay technique (EMIT).
Enzyme Immunoassay
owl:Class
Immunologic, Enzyme Linked Immunoassay
Laboratory Procedure
C17455
Enzyme Immunoassay
C0086231
Immunoenzyme Procedure
Enzyme Immunoassay
Conceptual Entity
Infectious Dose
A quantity of a pathogen required to infect a tissue culture with measurable cytopathic effects.
Tissue Culture Infection Dose
C67449
Tissue Culture Infection Dose
TCID
CL371803
Tissue Culture Infection Dose
Tissue Culture Infection Dose
owl:Class
CL322438
Diagnostic Procedure
C38094
owl:Class
Small Bowel Follow Through Procedure
Small Bowel Follow Through Procedure
Small Bowel Follow Through Procedure
A procedure that examines motility and mucosal pattern of the small intestine and involves the patient drinking barium as well as having X-rays of the abdomen taken at intermittent intervals.
Small Bowel Follow Through Procedure
Radiography
CL370563
Therapeutic Thoracoscopy
owl:Class
Therapeutic Endoscopic Procedure
Therapeutic Thoracoscopy
Therapeutic Thoracoscopy
Therapeutic Thoracoscopy
Therapeutic or Preventive Procedure
C64969
Thoracoscopy
owl:Class
The extent to which a patient conforms to medical advice regarding prescribed regimen, lifestyle, dietary changes, follow-up schedule and other recommendations.
Patient Compliance
C39490
Personal Behavior
C1321605
Individual Behavior
Compliance
Patient Compliance
Patient Compliance
Patient Compliance
Trial Screen Failure
Trial Screen Failure
SCREEN FAILURE
CDISC SDTM Reason for Non-Completion Terminology
Idea or Concept
Clinical Data Interchange Standards Consortium Terminology
Trial Screen Failure
The failure of a potential subject of meeting one or more criteria required for participation in a trial.
C49628
Trial Screen Failure
CDISC
Trial Screening
owl:Class
CDISC SDTM Terminology
CL354296
<def-source>CDISC</def-source><def-definition>The potential subject who does not meet one or more criteria required for participation in a trial. (NCI)</def-definition>
Therapeutic or Preventive Procedure
Antiprogesterone Therapy
Antiprogestational Therapy
owl:Class
Endocrine Drug Therapy
Drug treatment to block the action of the female hormone progesterone.
CL030067
C15521
Antiprogesterone Therapy
Antiprogesterone Therapy
Antiprogesterone Therapy
Bronchoscopy with Bronchoalveolar Lavage
Bronchoscopy with Bronchoalveolar Lavage
C38042
Bronchoscopy with Bronchoalveolar Lavage
owl:Class
C1527222
Diagnostic Procedure
Bronchoscopy with Bronchoalveolar Lavage
Bronchoscopy/Lavage
Bronchoscopy
CL384777
Clinical Data Interchange Standards Consortium Terminology
Free Carnitine Measurement
Vitamin Measurement
Free Carnitine Measurement
CDISC SDTM Laboratory Test Terminology by Name
Carnitine, Free
Free Carnitine Measurement
owl:Class
CDISC
The determination of the amount of free carnitine present in a sample.
Free Carnitine Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the free carnitine in a biological specimen.</def-definition>
CDISC SDTM Terminology
CARNITF
CDISC SDTM Laboratory Test Terminology by Code
C74677
CDISC SEND Terminology
Laboratory Procedure
Audiometry
Audiometric Test
owl:Class
C0004286
Diagnostic Procedure
Audiometric Test
Audiometric Test
Disease Screening
Newborn Screening
Testing conducted utilizing a manual or microprocessor audiometer to test for hearing loss.
Audiometric Test
C38036
Hearing Test
owl:Class
Reaching
Reach
Reaching
C81004
Physical Activity
The act of stretching out your arm in order to get or touch something.
Reaching
Reaching
Daily or Recreational Activity
Population Attributable Risk
C20038
Population Attributable Risk
Risk Estimate
That proportion of disease in the whole population that can be ascribed to the risk factor of concern.
owl:Class
Population-Attributable Risk
Population Attributable Risk
CL014534
Quantitative Concept
Population Attributable Risk
PAR
Treatment of Bacterial Infectious Disease
Infection Prophylaxis and Management
C0338237
owl:Class
Antibiotic Therapy
C15620
Antibiotic Therapy
Antibiotic Therapy
Therapeutic or Preventive Procedure
Antibiotic Therapy
Treatment of bacterial infections with antibiotics.
Pericardiectomy
C51643
Pericardiectomy
Pericardiectomy
Excision of Pericardium
Procedure_Has_Excised_Anatomy only Pericardium
Surgical removal of all or part of the pericardium.
C0031042
Cardiovascular Surgical Procedure
Therapeutic or Preventive Procedure
owl:Class
Pericardiectomy
Cardiac Therapeutic Procedure
Spectroscopy
Analysis of the absorption or transmittance of light in the visible region of the electromagnetic spectrum by a specific compound. By itself, this technique does not lead to the identification of a substance, but analysis of the spectrum (absorption versus wavelength) can help identify the presence of specific chromophores in the molecule. When the identity of the compound is known, determination of the absorbance at a specific wavelength yields quantitative information about the material analyzed.
Photometry/Spectrum Analysis, Visible Light
CL000710
Photometry/Spectrum Analysis, Visible Light
owl:Class
Photometry/Spectrum Analysis, Visible Light
Diagnostic Procedure
Laboratory Procedure
Photometry/Spectrum Analysis, Visible Light
C18938
Marriage Rate
Quantitative Concept
Marriage Rate
Population-Based Statistic
C53347
Marriage Rate
Marriage Rate
owl:Class
C0681672
Laboratory Procedure
Gene Expression Analysis
Gene Expression Analysis
Gene Expression Analysis
CL366363
owl:Class
C63479
Gene Expression Analysis
Molecular Analysis
Leukocyte Therapy
Vaccine-Draining Lymph Node Lymphocyte Therapy
Therapeutic or Preventive Procedure
C62735
Vaccine-Draining Lymph Node Lymphocyte Therapy
CL034741
Vaccine-Draining Lymph Node Lymphocyte Therapy
Vaccine-Draining Lymph Node Lymphocyte Therapy
owl:Class
Multiparametric Analysis
The fitting of data to multivariable deterministic or statistical models; extraction of the number of independent parameters that contribute to the observable value of a function; the execution of an experimental test or procedure in which multiple parameters are monitored simultaneously.
CL004156
Multiparametric Analysis
C19423
Research Activity
Multiparametric Analysis
Multiparametric Analysis
Statistical Technique
owl:Class
Dental Intrusion
Dental Intrusion
Orthodontic Treatment
A translational form of tooth movement directed apically and parallel to the long axis.
Intrusion
C82127
Dental Intrusion
Dental Intrusion
owl:Class
Therapeutic or Preventive Procedure
Biopsy of Breast
Excisional Biopsy of Breast
Excisional Biopsy
Excisional Biopsy of Breast
owl:Class
Removal of tissue from the breast for microscopic examination, involving surgical excision of a portion of the breast.
Excisional Biopsy of Breast
Excisional Biopsy of Breast
Diagnostic Procedure
C51633
CL353351
The determination of the amount of peptide YY present in a sample.
C80202
Protein or Enzyme Type Measurement
Peptide YY Measurement
Peptide YY Measurement
Peptide YY Measurement
Peptide YY Measurement
owl:Class
Laboratory Procedure
Laboratory Procedure
Urine N-Telopeptide Measurement
C81928
Urine N-Telopeptide Measurement
N-Telopeptide Measurement
Urine Chemistry Measurement
Urine N-Telopeptide Measurement
owl:Class
Urine N-Telopeptide Measurement
Surveillance, Epidemiology, and End Results Program
Cancer Surveillance Project
Governmental or Regulatory Activity
A cancer registry mandated under the National Cancer Act of 1971 to operate and maintain a population-based cancer reporting system, reporting periodically estimates of cancer incidence and mortality in the United States. The Surveillance, Epidemiology, and End Results (SEER) Program is a continuing project of the National Cancer Institute of the National Institutes of Health. Among its goals, in addition to assembling and reporting cancer statistics, are the monitoring of annual cancer incident trends and the promoting of studies designed to identify factors amenable to cancer control interventions. (From a brochure of the National Cancer Institute, NIH Publication No. 91-3074, October 1990)
Surveillance, Epidemiology, and End Results Program
SEER-Surveillance, Epidemiology, and End Results
Research Activity
Surveillance, Epidemiology, and End Results Program (SEER)
SEER
C0242638
Surveillance, Epidemiology, and End Results Program
C15432
Surveillance, Epidemiology, and End Results Program
owl:Class
Drug Abuse
Drug Abuse
C16522
Drug Abuse
Recreational Drug Use
The use of a drug for a reason other than which it was intended or in a manner or in quantities other than directed.
Substance Abuse
Drug Abuse
Individual Behavior
owl:Class
C0013146
Sampling Method
CL025354
Multistage Sampling
Multi-Stage Sampling
Quantitative Concept
Multi-Stage Sampling
C71515
Multi-Stage Sampling
owl:Class
Multi-Stage Sampling
Adjuvant Study
Neoadjuvant Study
Neoadjuvant Study
C15566
Neoadjuvant Study
study, neoadjuvant
Research Activity
owl:Class
CL030572
Neoadjuvant Study
CL384306
INTLK28
Interleukin 28 Measurement
CDISC SEND Terminology
Clinical Data Interchange Standards Consortium Terminology
Interleukin 28
CDISC SDTM Laboratory Test Terminology by Code
Interleukin 28 Measurement
Interleukin 28 Measurement
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Name
The determination of the amount of interleukin 28 present in a sample.
C74825
Laboratory Procedure
Interleukin 28 Measurement
<def-definition>A measurement of the interleukin 28 in a biological specimen.</def-definition><def-source>CDISC</def-source>
Cytokine Measurement
owl:Class
C61022
Laboratory Procedure
Serum Chemistry Measurement
Serum Bicarbonate Measurement
Serum Bicarbonate Measurement
Serum Bicarbonate Measurement
C0428301
owl:Class
A quantitative measurement of the amount of bicarbonate present in a sample of serum.
Serum Bicarbonate Measurement
SAFETY
CL355661
Safety Study
Safety Study
<def-source>CDISC</def-source><def-definition>A study of the relative safety of treatment of a disease. Usually this is a Phase I or II trial. (NCI)</def-definition>
A study of the relative safety of treatment of a disease. Usually this is a Phase I or II trial.
owl:Class
Safety Study
CDISC SDTM Terminology
C49667
CDISC
CDISC SDTM Trial Type Terminology
Safety Study
Clinical Data Interchange Standards Consortium Terminology
Research Activity
Trial Type
G-Banding
G-Banding
G-Banding
Laboratory Procedure
owl:Class
G-Banding
C19478
Chromosome Banding
Use of Giemsa stain to produce a characteristic staining pattern on chromosomes
CL004371
LDH Isoenzyme 1/LDH
Clinical Data Interchange Standards Consortium Terminology
C79451
LDH Isoenzyme 1 to LDH Ratio Measurement
<def-definition>A relative measurement (ratio or percentage) of the lactate dehydrogenase isoenzyme 1 to total lactate dehydrogenase in a biological specimen.</def-definition><def-source>CDISC</def-source>
LDH Isoenzyme 1 to LDH Ratio Measurement
LDH Isoenzyme 1 to LDH Ratio Measurement
owl:Class
Protein or Enzyme Type Measurement
The determination of the ratio of LDH isoenzyme 1 compared to total LDH present in a sample. The measurement may be expressed as a ratio or percentage.
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
LDH Isoenzyme 1 to LDH Ratio Measurement
CDISC SEND Terminology
Laboratory Procedure
LDH1LDH
CDISC SDTM Laboratory Test Terminology by Name
arteriography
owl:Class
Arteriography
C16308
Arteriography
The X-ray examination of the arterial blood vessels.
Angiography
Arteriography
<def-source>NCI-GLOSS</def-source><def-definition>(ar-TEE-ree-AH-gra-fee) A procedure to x-ray arteries. The arteries can be seen because of an injection of a dye that outlines the vessels on an x-ray.</def-definition>
Arteriography
Diagnostic Procedure
C0003844
CL356314
Quantitative Concept
Multinomial Distribution
A discreet probability distribution, which is a generalization of the binomial distribution. This distribution models systems in which each trial results in one of a finite set of outcomes with a fixed probability.
C53210
Discrete Distribution
owl:Class
Multinomial Distribution
Multinomial Distribution
Multinomial Distribution
Inguinofemoral Lymphadenectomy
owl:Class
Inguinofemoral Lymphadenectomy
C74540
C0398408
Lymphadenectomy
This surgery is used in the treatment of vulvar cancers.
Inguinofemoral Lymphadenectomy
Therapeutic or Preventive Procedure
The surgical removal of superficial inguinal lymph nodes and deep femoral lymph nodes.
Diagnostic Procedure
Inguinofemoral Lymphadenectomy
Treatment with injections of antibodies to directly destroy specific, usually cancerous, cells or to stimulate the immune system to destroy those cells.
C15542
Antibody Therapy
CL030484
<def-source>NCI-GLOSS</def-source><def-definition>Treatment with an antibody, a substance that can directly kill specific tumor cells or stimulate the immune system to kill tumor cells.</def-definition>
Antibody Therapy
owl:Class
Immunotherapy
antibody therapy
Antibody Therapy
Antibody Therapy
Therapeutic or Preventive Procedure
HER2/Neu Positive
CL374451
HER2/Neu Positive
HER2/Neu Positive
Her2/Neu Status
Clinical Attribute
owl:Class
HER2/Neu Positive
C68748
Isolated Perfusion
C15296
Isolated Perfusion
perfusion, isolated
<def-source>MSH2001</def-source><def-definition>Neoplasm drug therapy involving an extracorporeal circuit with temporary exclusion of the tumor-bearing area from the general circulation during which high concentrations of the drug are perfused to the isolated part.</def-definition>
Perfusion
Therapeutic or Preventive Procedure
owl:Class
C0031006
Isolated Perfusion
Isolated Perfusion
Unrehydrated GT
Unrehydrated Guaiac Test
CL384190
Unrehydrated Guaiac Test
Diagnostic Procedure
owl:Class
The assay slide or paper is coated with guaiac and a stool sample and hydrogen peroxide are applied. Fragmented hemoglobin has peroxidase activity and can oxidize the guaiac, which results in the development of blue color.
Unrehydrated Guaiac Test
A fecal occult blood test that uses a colorimetric assay to detect fragmented hemoglobin in stool. The assay slides or paper are not hydrated during sample processing.
C74539
Laboratory Procedure
Unrehydrated Guaiac Test
Fecal Occult Blood Test
Low-LET Electron Therapy
C15457
therapy, low-LET electron
Low-LET Electron Therapy
CL029155
Therapeutic or Preventive Procedure
Low-LET Electron Therapy
owl:Class
Radiation Therapy
Low-LET Electron Therapy
owl:Class
Electroencephalography
C0013819
Diagnostic Procedure
EEG
Diagnostic Procedure
The neurophysiologic exploration of the electrical activity of the brain by the application of electrodes to the scalp. The resulting traces are known as an electroencephalogram (EEG). This test is used to assess brain damage, epilepsy and other problems.
C38054
Electroencephalography
Electroencephalography
Electroencephalography
Infrared Photocoagulation Therapy
Infrared Photocoagulation Therapy
Infrared Photocoagulation Therapy
owl:Class
Phototherapy
C62730
CL336516
Infrared Photocoagulation Therapy
Therapeutic or Preventive Procedure
Research Activity
Diagnostic Procedure
Purdue Pegboard Test
C0204462
C33899
owl:Class
Purdue Pegboard Test
Purdue Pegboard Test
Purdue Pegboard Test
The Purdue Pegboard test measures finger dexterity and hand-eye coordination by testing an individual's ability to move hands, fingers, and arms (gross motor movement) and to control movements of small objects (fingertip dexterity). Measurements of the right hand, left hand, and both hands are part of the test.
CL355604
Wedge Resection of Lung
Wedge Resection of Lung
owl:Class
Wedge Excision of Lung
Therapeutic or Preventive Procedure
Procedure_Has_Partially_Excised_Anatomy only Lung
Wedge Resection of Lung
Thoracic Surgical Procedure
Wedge Resection of Lung
Surgical removal of a wedge-shaped section of lung.
C51625
Therapeutic Laparoscopic Surgery
Therapeutic or Preventive Procedure
Therapeutic Laparoscopic Surgery
CL370556
Therapeutic Laparoscopic Surgery
Therapeutic Surgical Procedure
Laparoscopic Surgery
Therapeutic Laparoscopic Surgery
owl:Class
C65014
Clinical Trial Eligibility Criteria
owl:Class
Estrogen Receptor Status
The estrogen receptor level measured in a primary tumor or in metastases. There are essentially two distinct forms of breast cancer, one that tends to have an early onset and is characterized by an ER- status, and one that tends to have a late onset and is characterized by an ER+ status. However, these two variants tend to overlap with respect to age, so it is possible for a young woman to have a "late-onset" form of breast cancer and for an older woman to have an "early-onset" variant of the disease.
Estrogen Receptor Status
C16150
ER Status
Estrogen Receptor Status
CL014332
Estrogen Receptor Status
Clinical Attribute
Prevention of Liver Cancer
Prevention of Liver Cancer
Prevention of Liver Cancer
CL031726
Prevention of Liver Cancer
Cancer Prevention
Therapeutic or Preventive Procedure
owl:Class
C15668
Liver Cancer Prevention
owl:Class
C64253
Questionnaire Administration
Informational Intervention
Questionnaire Administration
Questionnaire Administration
Questionnaire Administration
Health Care Activity
CL369341
Cancer Pain Management
Narcotic Rotation
Narcotic Substitution
Opioid Rotation
Narcotic Switching
Opioid Rotation
Opioid Rotation
Opioid Switching
Shifting from one opiate to another to maintain effectiveness in analgesia while minimizing the side-effect profile.
owl:Class
Therapeutic or Preventive Procedure
C21083
CL100624
Opioid Rotation
Pharmacologic Management
Opioid Substitution
Ovarian Implantation
Therapeutic or Preventive Procedure
Ovarian Implantation
owl:Class
Ovarian Implantation
Surgical Procedure by Method
Ovarian Implantation
CL320067
C29897
in vitro Sensitivity-Directed Chemotherapy
in vitro Sensitivity-Directed Chemotherapy
Therapeutic or Preventive Procedure
C15578
in vitro Sensitivity-Directed Chemotherapy
in vitro Sensitivity-Directed Chemotherapy
owl:Class
CL030742
Uses the results of a chemosensitivity testing assay to tailor the treatment to the individual.
Chemotherapy
CDISC
owl:Class
C64812
Lipid Measurement
Triglyceride Measurement
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
<def-source>CDISC</def-source><def-definition>A measurement of the triglycerides in a biological specimen.</def-definition>
Triglyceride Measurement
Triglyceride Measurement
Triglyceride Measurement
A quantitative measurement of the amount of triglyceride present in a sample.
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
TRIG
CDISC SDTM Terminology
C0202236
Triglycerides
CDISC SEND Terminology
Statistical Imputation
Screening Observation Carried Forward Imputation Technique
Screening Observation Carried Forward Imputation Technique
Screening Observation Carried Forward Imputation Technique
owl:Class
C81200
Screening Observation Carried Forward Imputation Technique
The substitution of missing data with the subject's screening observation values that are not missing.
Quantitative Concept
Culturing, in vitro Invertebrate
C19346
Tissue Culture
owl:Class
CL003848
Maintenance of invertebrate tissue after removal from the body, by placing in a vessel with a sterile nutritive medium.
Laboratory Procedure
Culturing, in vitro Invertebrate
Culturing, in vitro Invertebrate
Culturing, in vitro Invertebrate
Laboratory Procedure
Percent Hemoglobin S
The determination of the ratio of Hemoglobin S compared to total Hemoglobin present in a sample. The measurement may be expressed as a ratio or percentage.
Hemoglobin S to Total Hemoglobin Ratio Measurement
Hemoglobin S to Total Hemoglobin Ratio Measurement
Hemoglobin S to Total Hemoglobin Ratio Measurement
Hemoglobin S to Total Hemoglobin Ratio Measurement
Hemoglobin Measurement
owl:Class
Newborn Screening
C81279
Hyperbaric Treatment
Therapeutic Procedure
Hyperbaric Oxygen Therapy
Hyperbaric Oxygen Therapy
C0020431
Hyperbaric Therapy
Hyperbaric Oxygen Therapy
owl:Class
C38065
The use of a pressurized chamber for the delivery of oxygen in higher concentrations for therapeutic benefit. Useful in the treatment of severe burns, peripheral vascular disease, carbon monoxide poisoning and decompression illness.
Hyperbaric Oxygen Therapy
Therapeutic or Preventive Procedure
C1285573
C45447
Genotyping
owl:Class
The process of assessing genetic variation present in an individual.
Genotyping
Molecular Biology Research Technique
Genotyping
Genetic Technique
Genotyping
Radioisotope Therapy
Radioisotope Therapy
Treatment of a disease by means of exposure of the target or the whole body to radioisotopes.
Therapeutic or Preventive Procedure
C0203608
Radioisotope Therapy
C62728
owl:Class
Radiation Therapy
Radioisotope Therapy
Pseudoephedrine Measurement
The determination of the amount of pseudoephedrine present in a sample
Pseudoephedrine
<def-definition>A measurement of the pseudoephedrine present in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Laboratory Test Terminology by Name
Pseudoephedrine Measurement
CNS Stimulant Drug Measurement
owl:Class
CDISC SEND Terminology
C74696
C0524257
PSDEPHD
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Terminology
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Code
Pseudoephedrine Measurement
Pseudoephedrine Measurement
HDL-Cholesterol Subclass 2 Measurement
HDL-Cholesterol Subclass 2 Measurement
HDL-Cholesterol Subclass 2 Measurement
HDL-Cholesterol Subclass 2 Measurement
Lipid Measurement
C80187
The determination of the amount of HDL-cholesterol subclass 2 present in a sample.
Laboratory Procedure
owl:Class
Amputation of Toe
Amputation of Toe
Amputation of Toe
Amputation of Toe
The surgical removal of a toe.
C51622
Amputation
Therapeutic or Preventive Procedure
Procedure_Has_Excised_Anatomy only Toe
Orthopedic Surgical Procedure
owl:Class
C0188602
The determination of the amount of neuropeptide Y present in a sample.
C74892
Neuropeptide Y
<def-definition>A measurement of the neuropeptide Y in a biological specimen.</def-definition><def-source>CDISC</def-source>
NPY
Neuropeptide Y Measurement
CL384332
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
Protein or Enzyme Type Measurement
Neuropeptide Y Measurement
Clinical Data Interchange Standards Consortium Terminology
owl:Class
Neuropeptide Y Measurement
CDISC SEND Terminology
Neuropeptide Y Measurement
CDISC SDTM Laboratory Test Terminology by Code
Dehydroepiandrosterone Measurement
CDISC SDTM Terminology
Dehydroisoandrosterone
The determination of the amount of dehydroepiandrosterone hormone present in a sample.
C74852
C0373598
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Laboratory Test Terminology by Code
<def-definition>A measurement of the dehydroepiandrosterone hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
Clinical Data Interchange Standards Consortium Terminology
CDISC SEND Terminology
DHEA
Dehydroepiandrosterone Measurement
Dehydroepiandrosterone Measurement
Dehydroepiandrosterone Measurement
owl:Class
Hormone Measurement
Laboratory Procedure
Dehydroepiandrosterone
Multimodality Therapy
Therapeutic or Preventive Procedure
<def-source>NCI-GLOSS</def-source><def-definition>Therapy that combines more than one method of treatment.</def-definition>
Multimodality Therapy
multimodal treatment
multimodality treatment
combined modality treatment
Combined Treatment Modalities
C15212
combined treatment
combined modality therapy
C0009429
Multimodality Therapy
Multimodal Therapy
Multimodality Treatment
owl:Class
Use of two or more simultaneous or consecutive treatment modalities; e.g., surgery + radiation, or radiation + immunotherapy. Does not refer to use of two or more chemotherapeutic agents.
Therapeutic Procedure
Combination Therapy
Multimodality Therapy
Dental Procedure
C60713
Air-Drying
Therapeutic or Preventive Procedure
CL360573
Air-Drying
Air-Drying
Drying by exposure to forced air.
Air-Drying
owl:Class
The standard deviations of the sample in a frequency distribution, obtained by dividing the standard deviation by the square root of the total number of cases in the frequency distribution.
Quantitative Concept
C53323
Standard Error
Standard Error
CL355813
Dispersion
Standard Error
owl:Class
Standard Error
Electrophoretic Light Scattering
Light Scattering
Electrophoretic Light Scattering
CL387707
A technique for determining the zeta potential of a sample through the detection of the motion of dispersed particles relative to a fluid under the influence of an oscillating electric field.
Electrophoretic Light Scattering
C78868
Electrophoretic Light Scattering
Laboratory Procedure
Research Activity
owl:Class
Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry
Laboratory Procedure
In MALDI-TOF, a laser pulse is fired into a protein or peptide sample contained in a light-absorbing matrix. A small explosion vaporizes and ionizes the sample. In the presence of a high electric field, peptide ions are accelerated down an evacuated flight tube. Because large particles travel more slowly than small ones, the masses of the ionized particles are determined by measuring their arrival time at the end of the tube
Matrix-Assisted Laser Desorption Ionization Time-of-Flight MS
CL012515
owl:Class
Matrix-Assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry
Matrix-Assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry
C19935
MALDI-TOF Mass Spectrometry
Matrix-Assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry
Matrix-Assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry
Mass Spectrometry
Therapeutic or Preventive Procedure
Immunoaugmentative Therapy
CAM Pharmacological or Biological Treatment
Immunoaugmentative Therapy
C67029
owl:Class
Immunoaugmentative Therapy
CL371531
Immunoaugmentative Therapy
Ommaya Reservoir Tap
A procedure to remove cerebrospinal fluid from the reservoir to detect any abnormal cells.
Ommaya Reservoir Tap
Biospecimen Collection
C38077
Ommaya Reservoir Access
owl:Class
CL322427
Diagnostic Procedure
Ommaya Reservoir Tap
Ommaya Reservoir Tap
C15556
Prevention of Skin Cancer
owl:Class
Prevention of Skin Cancer
Skin Cancer Prevention
CL030498
Therapeutic or Preventive Procedure
Prevention of Skin Cancer
Cancer Prevention
Prevention of Skin Cancer
CL000456
Therapeutic or Preventive Procedure
High Dose Chemotherapy
Chemotherapy
owl:Class
High Dose Chemotherapy
High Dose Chemotherapy
High Dose Chemotherapy
C15807
Pavlovian Conditioning
Conditioning
Pavlovian Conditioning
Pavlovian Conditioning
owl:Class
Functional Concept
Pavlovian Conditioning
C41215
A classical conditioning procedures that present different stimuli in temporal proximity (contiguity), but where resulting responses have no reinforcing or aversive consequences. Named after the author of the experiments (Dr. I. Pavlov) in which dogs were conditioned to salivate at the sound of a tone.
C0009649
Embolization Therapy
Embolization Therapy
Embolization Therapy
embolization
therapy, embolization
Embolization Therapy
C0013931
<def-source>NCI-GLOSS</def-source><def-definition>(EM-bo-lih-ZAY-shun) The blocking of an artery by a clot or foreign material. Embolization can be done as treatment to block the flow of blood to a tumor.</def-definition>
C15230
<def-source>MSH2001</def-source><def-definition>A method of hemostasis utilizing various agents such as Gelfoam, silastic, metal, glass, or plastic pellets, autologous clot, fat, and muscle as emboli. It has been used in the treatment of spinal cord and INTRACRANIAL ARTERIOVENOUS MALFORMATIONS, renal arteriovenous fistulas, gastrointestinal bleeding, epistaxis, hypersplenism, certain highly vascular tumors, traumatic rupture of blood vessels, and control of operative hemorrhage.</def-definition>
owl:Class
Therapeutic Procedure
Therapeutic or Preventive Procedure
CLCTRIOL
Calcitriol Measurement
CDISC SDTM Laboratory Test Terminology by Name
Hormone Measurement
owl:Class
CL384379
CDISC SEND Terminology
Laboratory Procedure
<def-definition>A measurement of the calcitriol hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
Clinical Data Interchange Standards Consortium Terminology
C74849
Calcitriol
CDISC SDTM Laboratory Test Terminology by Code
Calcitriol Measurement
Calcitriol Measurement
CDISC SDTM Terminology
The determination of the amount of calcitriol hormone present in a sample.
Calcitriol Measurement
Therapeutic or Preventive Procedure
Arthrodesis
Arthrodesis
Surgical fixation or immobilization of a joint, performed to allow bones to fuse or join together.
Arthrodesis
C0003881
C52007
Arthrodesis
owl:Class
Orthopedic Surgical Procedure
Clinical Attribute
No Prior Therapy
owl:Class
No Prior Therapy
CL001439
No Prior Therapy
Prior Therapy
No Prior Therapy
C15903
No prior cancer treatment.
Head and Neck Surgery
CL354857
C51891
Tympanomastoidectomy
Procedure_Has_Excised_Anatomy only 'Tympanic Membrane'
Surgery involving the complete or partial excision of the typanic membrane, and complete or partial removal of the mastoid process.
owl:Class
Tympanomastoidectomy
Procedure_Has_Excised_Anatomy only 'Mastoid Process'
Tympanomastoidectomy
Tympanomastoidectomy
Therapeutic or Preventive Procedure
Therapeutic or Preventive Procedure
Bladder Irrigation
Bladder Irrigation
simple bladder irrigation
C15397
owl:Class
Therapeutic Procedure
Instillation of a solution into the bladder to provide cleansing or medication.
Bladder Irrigation
C0194423
Bladder Irrigation
irrigation of urinary bladder
Laser Interstitial Thermal Therapy
Laser Interstitial Thermal Therapy
owl:Class
Laser Interstitial Thermal Therapy
Thermal Ablation Therapy
CL374463
C68680
Therapeutic or Preventive Procedure
LITT
Laser Interstitial Thermal Therapy
Perimenopausal
Perimenopausal
Perimenopausal
Menopausal Status
C15692
<def-source>NCI-GLOSS</def-source><def-definition>The time of a woman's life when menstrual periods become irregular. Refers to the time near menopause.</def-definition>
perimenopausal
C0677925
owl:Class
Clinical Attribute
Perimenopausal
WHO Analgesic Method
WHO Analgesic Method
owl:Class
WHO Analgesic Method
CL100637
C21122
WHO Analgesic Method
Therapeutic or Preventive Procedure
Three-Step Analgesic Ladder
Pain Management Method
Developed to promote the sequential use of drugs to achieve effective pain relief. The first step is a non-opioid medication (such as aspirin, paracetamol, or ibuprofen). If this does not relieve the pain, an opioid for mild to moderate pain (such as codeine) should be added. When an opioid for mild to moderate pain in combination with a non-opioid medication does not provide effective analgesia, then an opioid for moderate to severe pain (such as morphine or one in the therapeutic group of morphine) should be substituted. Adjuvant drugs should be given at any point during drug treatment to relieve adverse effects of analgesics, to enhance pain relief, and to treat concomitant psychological disturbances such as insomnia, anxiety, and depression. (WHO)
Laboratory Procedure
Radioactive Sequencing
Radioactive Sequencing
Nucleic Acid Sequencing
Molecular Biology Research Technique
CL008177
owl:Class
Radioactive Sequencing
Classical technique for sequencing nucleic acids in which visualization of the bases in the sequence relies on the use of radioactive materials, either radiolabeled nucleic acid strands in the chemical degradation method (Maxam-Gilbert), or radiolabeled nucleotides in the dideoxy-termination method (Sanger).
Radioactive Sequencing
C19658
Esophageal Dilation
C70908
A technique to stretch or open a blocked or constricted portion of the esophagus.
Esophageal Dilation
Digestive System Surgery
owl:Class
C0740287
Esophageal Dilation
Therapeutic or Preventive Procedure
Esophageal Dilation
owl:Class
C51767
Excision
Excision, Skin
Excision of Skin
Skin Excision
CL354233
Skin Excision
Skin Excision
Therapeutic or Preventive Procedure
Skin Excision
Research Activity
CL004893
owl:Class
Investigation of Mechanisms of Drug Resistance
Basic Science Research
Investigation of Mechanisms of Drug Resistance
Basic research to understand the mechanisms that cells use to avoid being killed by cytotoxic drugs.
C16038
Investigation of Mechanisms of Drug Resistance
Investigation of Mechanisms of Drug Resistance
Therapy to cause release of stem cells from the bone marrow into the peripheral blood circulation for the purpose of leukapheresis, prior to stem cell transplantion. Hematopoietic growth factors or chemotherapeutic agents often are used to stimulate the mobilization.
Stem Cell Mobilization Therapy
CL365154
Stem Cell Mobilization Therapy
Mobilization Therapy
owl:Class
Therapeutic Procedure
Stem Cell Mobilization Therapy
C62604
Health Care Activity
Stem Cell Mobilization Therapy
owl:Class
Newborn Screening
C81302
VBAC
The method referring to the delivery of a fetus through the vaginal canal after the mother has had a cesarean delivery with a previous pregnancy.
Therapeutic or Preventive Procedure
Vaginal Birth after Cesarean
Vaginal Birth after Cesarean
Birth Method of Delivery
Vaginal Birth after Cesarean
Vaginal Birth after Cesarean
Liquid Chromatography Mass Spectrometry
Liquid Chromatography Mass Spectrometry
C18475
Liquid Chromatography-Mass Spectrometry
Liquid Chromatography Mass Spectrometry
Liquid Chromatography Mass Spectrometry
C0872318
owl:Class
LC/MS is a hyphenated technique, combining the separation power of liquid chromatography (LC), an analytical chromatographic technique for separating ions or molecules dissolved in a solvent, with the detection power of mass spectrometry(MS), a technique to separate gas phase ions according their m/z (mass to charge ratio) value. Used for drug screening, pharmacology studies, environmental analyses and forensics.
Laboratory Procedure
Liquid Chromatography
Mass Spectrometry
LC/MS
Natural History
Elucidate the progression of HIV infection, from its earliest stages through long-term sequelae.
Conceptual Entity
C15816
Natural History of Progression of HIV-related Diseases
CL000575
owl:Class
Natural History of Progression of HIV-related Diseases
Natural History of Progression of HIV-related Diseases
Natural History of Progression of HIV-related Diseases
Tumor Formation in Athymic Mice
Tumor Formation in Athymic Mice
Carcinogenicity Test
Laboratory Procedure
C16217
owl:Class
CL026261
Tumor Formation in Athymic Mice
Tumor Formation in Athymic Mice
Activity
Probe Correction Method
owl:Class
C64232
Make no adjustment to the perfect match (PM) probe levels. Defined in the documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html
PM Only Probe Correction Method
CL369336
PM Only Probe Correction Method
PM Only Probe Correction Method
PM Only Probe Correction Method
Sequestrectomy
Sequestrectomy
Procedure_Has_Partially_Excised_Anatomy only Bone
Sequestrectomy
Removal of a fragment of dead bone separated from healthy bone as a result of injury or disease.
C0185216
owl:Class
C63750
Therapeutic or Preventive Procedure
Orthopedic Surgical Procedure
Sequestrectomy
Surgery to remove a portion of the cranium.
C51791
Craniectomy
Therapeutic or Preventive Procedure
Craniectomy
owl:Class
Excision of Bone
Procedure_Has_Partially_Excised_Anatomy only Skull
Craniectomy
Head and Neck Surgery
CL353294
Craniectomy
C16291
Angiography, Digital Subtraction
Angiography
A technique which subtracts two images that are obtained before and after contrast media is administered to the patient for the purpose of studying blood vessels.
Diagnostic Procedure
owl:Class
<def-source>MSH2001</def-source><def-definition>A method of delineating blood vessels by subtracting a tissue background image from an image of tissue plus intravascular contrast material that attenuates the X-ray photons. The background image is determined from a digitized image taken a few moments before injection of the contrast material. The resulting angiogram is a high-contrast image of the vessel. This subtraction technique allows extraction of a high-intensity signal from the superimposed background information. The image is thus the result of the differential absorption of X-rays by different tissues.</def-definition>
Digital Subtraction Angiography
Digital Subtraction Angiography
Medical Imaging, Digital Subtraction Angiography
Digital Subtraction Angiography
C0002979
Digital Subtraction Angiography
Incremental Spiral CT
Spiral CT
Incremental Spiral CT
C19914
A type of computed tomography in which the patient is moved through the scanner in increments rather than in a continuous fashion.
owl:Class
Diagnostic Procedure
CL009740
Incremental Spiral CT
Incremental Spiral CT
CL365046
Inductively-Coupled Plasma Mass Spectrometry
Laboratory Procedure
Inductively Coupled Plasma Mass Spectrometry
Inductively-Coupled Plasma Mass Spectrometry
ICPMS
A mass spectrometry technique that uses inductively-coupled plasma generated from argon gas to atomize and ionize a sample. The resulting ions are separated and analyzed using a mass spectrometer.
ICP-MS
C62328
Inductively-Coupled Plasma Mass Spectrometry
owl:Class
Spectrometry
Inductively-Coupled Plasma Mass Spectrometry
C54153
Procurement
Procurement
owl:Class
Procurement
CL357845
The process of obtaining services, supplies, and equipment in conformance with applicable laws and regulations.
Action
Procurement
Activity
Qualitative Concept
The second significance level for the detection p-value in an absolute analysis.
Alpha2 Significance
Alpha2 Significance
C67051
Alpha2 Significance
Alpha2 Significance
CL371499
Alpha2
owl:Class
Statistical Significance
Therapeutic or Preventive Procedure
Bilateral Oophorectomy
owl:Class
Procedure_Has_Completely_Excised_Anatomy only 'Right Ovary'
Procedure_Has_Completely_Excised_Anatomy only 'Left Ovary'
C0278321
Surgery to remove both ovaries.
Bilateral Oophorectomy
Oophorectomy
Bilateral Oophorectomy
C51590
Bilateral Oophorectomy
<def-source>CDISC</def-source><def-definition>A measurement of the Vitamin B12 in a serum specimen.</def-definition>
Vitamin Measurement
A quantitative measurement of the amount of vitamin B12 present in a sample.
Vitamin B12 Measurement
VITB12
Vitamin B12 Measurement
Vitamin B12 Measurement
Vitamin B12 Measurement
CDISC
CDISC SEND Terminology
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
C64817
owl:Class
Vitamin B12
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
C0202252
C0860838
C67076
A diagnostic procedure in which a two-dimensional picture of all or part of the adrenal glands is obtained through the use of radioisotopes.
owl:Class
Adrenal Scintigraphy
Adrenal Scintigraphy
Adrenal Scintigraphy
Radionuclide Imaging
Diagnostic Procedure
Adrenal Scintigraphy
Molecular Genetic Technique
CL001113
Antisense Technology
The use of nucleic acid oligomers to bind to a specific mRNA to deter protein production.
Antisense Technology
Antisense Technology
C19128
owl:Class
Molecular Biology Research Technique
Antisense Technology
CL370565
Therapeutic Videothoracoscopy
owl:Class
Videothoracoscopy
C64970
Therapeutic Videothoracoscopy
Therapeutic Videothoracoscopy
Therapeutic Videothoracoscopy
Therapeutic Thoracoscopy
Therapeutic or Preventive Procedure
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Terminology
CD3 T Cell to Lymphocyte Ratio Measurement
Clinical Data Interchange Standards Consortium Terminology
<def-source>CDISC</def-source><def-definition>A relative measurement (ratio or percentage) of CD3 T cells to all lymphocytes in a biological specimen.</def-definition>
CD3/Lymphocytes
CD3 T Cell to Lymphocyte Ratio Measurement
CL384745
CD3 T Cell to Lymphocyte Ratio Measurement
CD3 T Cell to Lymphocyte Ratio Measurement
Blood Cell Count Ratio Measurement
The determination of the ratio of CD3 T cells compared to lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
CDISC SDTM Laboratory Test Terminology by Name
CDISC
CD3LY
CDISC SEND Terminology
Laboratory Procedure
C74636
owl:Class
CDISC SEND Terminology
MGB
owl:Class
Myoglobin Measurement
Myoglobin
<def-definition>A measurement of myoglobin in a biological specimen.</def-definition><def-source>CDISC</def-source>
C79436
Myoglobin Measurement
Myoglobin Measurement
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Laboratory Test Terminology by Name
Clinical Data Interchange Standards Consortium Terminology
Myoglobin Measurement
Laboratory Procedure
Protein or Enzyme Type Measurement
The determination of the amount of myoglobin present in a sample.
C74736
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Terminology
CDISC
Clinical Data Interchange Standards Consortium Terminology
C0202100
C-peptide
CPEPTIDE
owl:Class
C-peptide Measurement
CDISC SEND Terminology
C-peptide Measurement
The determination of the amount of C-peptide present in a sample.
C-peptide Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the C (connecting) peptide of insulin in a biological specimen.</def-definition>
Protein or Enzyme Type Measurement
C-peptide Measurement
Gas Chromatography
owl:Class
Gas Chromatography
C0008555
Gas Chromatography
Gas Chromatography
Laboratory Procedure
C30014
A chromatographic technique in which the stationary phase is solid while the mobile phase is gaseous samples. The gaseous samples are separated based on their different adsorption ability to the solid phase.
GC
Column Chromatography
C0026025
Polarization Microscopy
Microscopy, Polarized Light
Polarization Microscopy
Polarization Microscopy
Polarization Microscopy
owl:Class
C16858
<def-source>MSH2001</def-source><def-definition>Microscopy using polarized light in which phenomena due to the preferential orientation of optical properties with respect to the vibration plane of the polarized light are made visible and correlated parameters are made measurable.</def-definition>
Laboratory Procedure
Light Microscopy
Any form of microscopy capable of detecting birefringent objects. Usually performed with a polarizing element below the stage to produce plane polarized light and an analyzer that is set to give total extinction of the background and thus to detect any birefringence.
C81952
The determination of the amount of eotaxin-1 present in a sample.
Eotaxin-1 Measurement
owl:Class
Eotaxin-1 Measurement
Eotaxin-1 Measurement
Chemokine Measurement
Eotaxin-1 Measurement
Cellular Assay
Laboratory Procedure
owl:Class
C16116
C51 Cytotoxicity Assay
C51 Cytotoxicity Assay
C51 Cytotoxicity Assay
CL008897
C51 Cytotoxicity Assay
Research Activity
Physiologic Imaging
Diagnostic Procedure
Functional Imaging
Functional Imaging
Functional Imaging
owl:Class
C19609
Imaging Technique
CL006986
Functional Imaging
The visualization of physiological, cellular or molecular processes in living tissue in real time as they take place in cells, for example, blood flow, oxygen consumption or glucose metabolism. (Bypass Budget)
Activity
Abnormal Cell
Disease, Disorder or Finding
Diagnostic, Therapeutic, and Research Equipment
Chemotherapy Regimen or Agent Combination
Experimental Organism Anatomical Concept
Gene Product
Activity
C43431
Diagnostic or Prognostic Factor
NCI Administrative Concept
Activity
Conceptual Entity
Biochemical Pathway
Activity
Organism
Biological Process
Retired Concept
Anatomic Structure, System, or Substance
owl:Class
Experimental Organism Diagnosis
Molecular Abnormality
Drug, Food, Chemical or Biomedical Material
An action taken in pursuit of an objective; the state of being active.
Property or Attribute
C0441655
Gene
Activity
owl:Class
Umbilical Cord Blood-Derived Lymphocyte Therapy
C71689
Leukocyte Therapy
Umbilical Cord Blood-Derived Lymphocyte Therapy
Umbilical Cord Blood-Derived Lymphocyte Therapy
CL378336
Umbilical Cord Blood-Derived Lymphocyte Therapy
Therapeutic or Preventive Procedure
Chemokine Measurement
The determination of the amount of lymphotactin present in a sample.
Lymphotactin Measurement
owl:Class
Lymphotactin Measurement
Lymphotactin Measurement
Lymphotactin Measurement
C81955
Combinatorial Synthesis of Biomolecules
owl:Class
Combinatorial Synthesis of Biomolecules
C18713
Combinatorial Synthesis
Combinatorial Synthesis of Biomolecules
Combinatorial Synthesis of Biomolecules
Activity
CL000244
Technique for making and testing many complex materials in parallel: computer guided synthesis in which all possible combinations are made. Combinatorial synthesis is not random, but systematic and repetitive, using sets of chemical "building blocks" to form a diverse set of molecular entities. Initial synthesis is usually made on a solid substrate. The technique lays down the materials in a checkerboard arrangement, as thin squares arranged in a grid. Scientists use combinatorial chemistry to create large populations of molecules, or libraries, that can be screened efficiently en masse. (NCI/OSP)
TT
C80365
Thrombin Clotting Time
Thrombin Time
Coagulation Study
Thrombin Time
Thrombin Time
TCT
Thrombin Time
owl:Class
A measurement of the time it takes a plasma sample to clot after adding the active enzyme thrombin.
Laboratory Procedure
Toll-Like Receptor Agonist Therapy
Toll-Like Receptor Agonist Therapy
Toll-Like Receptor Agonist Therapy
Toll-Like Receptor Agonist Therapy
C66888
Immunopotentiation Therapy
Therapeutic or Preventive Procedure
CL371333
owl:Class
C67027
A complimentary/alternative cancer therapy that uses antineoplastons to protect the body from disease.
Antineoplastons Therapy
owl:Class
Antineoplastons Therapy
Therapeutic or Preventive Procedure
Antineoplastons Therapy
CL371396
Antineoplastons Therapy
CAM Pharmacological or Biological Treatment
C51576
owl:Class
CL354433
A surgical procedure performed on the biliary tract.
Therapeutic or Preventive Procedure
Procedure_Has_Target_Anatomy only 'Biliary Tract'
Digestive System Surgery
Biliary Tract Surgery
Biliary Tract Surgery
Biliary Tract Surgery
Biliary Tract Surgery
owl:Class
Reverse Triiodothyronine Measurement
Reverse Triiodothyronine Measurement
C81968
Reverse Triiodothyronine Measurement
Reverse Triiodothyronine Measurement
Hormone Measurement
A measurement of the reverse triiodothyronine in a biological specimen.
Molecular Analysis
C51961
Laboratory Procedure
CL354000
Gene Rearrangement Analysis
Gene Rearrangement Analysis
Gene Rearrangement Analysis
owl:Class
Gene Rearrangement Analysis
owl:Class
Background Correction Method
Background Correction Method
Background Correction Method
C64234
Activity
CL369064
Background Correction Method
A method to adjust probe intensities to correct for background variation in intensities.
Statistical Technique
C15866
Vaccine Development, AIDS
Vaccines or candidate vaccines containing inactivated HIV or some of its component antigens and designed to prevent AIDS. Some vaccines containing antigens are recombinantly produced.
Vaccine Development, AIDS
Vaccine Development, AIDS
Health Care Activity
owl:Class
Vaccine Development, AIDS
CL001068
Vaccine Development
CDISC SDTM Trial Type Terminology
C49661
Pharmacogenomic Study
<def-source>CDISC</def-source><def-definition>A study of identification and analysis of genomic variations that affect the efficacy of a drug. Pharmacogenomic studies can potentially be predictive of an individual's drug-response or adverse reactions or susceptibility to iatrogenic disorders, and may also reveal new targets that can help in the design of new drugs. (NCI)</def-definition>
CDISC
owl:Class
Pharmacogenomic Study
Pharmacogenomic Study
Clinical Data Interchange Standards Consortium Terminology
A study of identification and analysis of genomic variations that affect the efficacy of a drug. Pharmacogenomic studies can potentially be predictive of an individual's drug-response or adverse reactions or susceptibility to iatrogenic disorders, and may also reveal new targets that can help in the design of new drugs.
Pharmacogenomic Study
CDISC SDTM Terminology
CL353600
Research Activity
PHARMACOGENOMIC
Human Pharmacology Study
Therapeutic or Preventive Procedure
C51645
owl:Class
Myomectomy
Surgical removal of part of the uterine body, frequently performed as a treatment for leiomyomas.
Partial Hysterectomy
Myomectomy
CL353552
Myomectomy
Myomectomy
Diagnostic Procedure
C0598836
Therapeutic or Preventive Procedure
Checkup is a general examination or inspection, especially one carried out by a doctor or dentist.
Check-up
Checkup
Physical Examination
Checkup
Checkup
Checkup
owl:Class
C41383
Magnet Therapy
C67034
Electromagnetic-Based Therapy
Magnet Therapy
CL371457
Magnet Therapy
owl:Class
Magnet Therapy
Therapeutic or Preventive Procedure
Tobacco Use, Chemoprevention
Studies that assess the administration of specific and/or dietary modifications to reverse or suppress the carcinogenic effects of tobacco and prevent the development of invasive cancer. (NCI/TRIP)
C15989
owl:Class
Tobacco Use, Chemoprevention
CL003968
Chemoprevention
Tobacco Use, Chemoprevention
Tobacco Use, Chemoprevention
Therapeutic or Preventive Procedure
Expression Technologies for DNA and RNA
In molecular biology, refers to the transcriptional regulation of a chimeric gene by the prokaryotic repressor/operator system of the tetracycline operon, permitting the production of a specific gene product or protein in a cell culture or a transgenic animal at controlled times. The chimeric gene contains the regulatory promoter elements of the tetracycline gene, and is transcriptionally regulated by the binding of recombinant tet repressor to these promoter elements in the absence of soluble tetracycline.
C20173
Tetracycline Control
Tetracycline Control
owl:Class
Tetracycline Control
Molecular Biology Research Technique
Tetracycline Control
CL024264
Leukocyte Banking
Laboratory Procedure
Leukocyte Banking
Blood Banking, Leukocyte
owl:Class
The typing, separation, and storage of leukocytes for subsequent transfusion to recipients.
Leukocyte Banking
CL000119
Leukocyte Banking
C15773
Repository Operation
Calcium Measurement
Laboratory Procedure
owl:Class
A quantitative measurement of the amount of calcium present in a sample of serum.
Serum Calcium Measurement
Serum Calcium Measurement
C61020
Serum Calcium Measurement
Serum Chemistry Measurement
C0728876
Serum Calcium Measurement
C18799
Fractionation, Centrifugation, Preparative
Preparative Centrifugation
owl:Class
Preparative Centrifugation
Preparative Centrifugation
CL000402
Preparative Centrifugation
A type of centrifugation used to separate cell components. Consists of two basic procedures: differential centrifugation and density gradient centrifugation.
Centrifugation
Laboratory Procedure
owl:Class
Triphasic Spiral CT
Triple-Phase Spiral CT
C19907
Diagnostic Procedure
A type of computed tomography whereby images of three separate phases of contrast medium perfusion are taken. In general, the phases examined are the arterial, venous and exitatory phase.
Triple-Phase Spiral CT
CL009733
Triple-Phase Spiral CT
Triple-Phase Spiral CT
Phased Spiral CT
Bite Cell to Erythrocyte Ratio Measurement
Bite Cell to Erythrocyte Ratio Measurement
CDISC SEND Terminology
Bite Cell to Erythrocyte Ratio Measurement
CDISC
Laboratory Procedure
Bite Cells/Erythrocytes
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Laboratory Test Terminology by Name
Bite Cell to Erythrocyte Ratio Measurement
owl:Class
<def-definition>A relative measurement (ratio or percentage) of bite cells (erythrocytes with the appearance of a bite having been removed, due to oxidative hemolysis) to all erythrocytes in a biological specimen.</def-definition><def-source>CDISC</def-source>
The determination of the ratio of bite cells compared to erythrocytes present in a sample. The measurement may be expressed as a ratio or percentage.
CL384274
C74634
Clinical Data Interchange Standards Consortium Terminology
Blood Cell Count Ratio Measurement
BTECERBC
CL378052
Mixed Purposeful Sampling
owl:Class
Matched Sampling
Mixed Purposeful Sampling
Mixed Purposeful Sampling
Mixed Purposeful Sampling
C71513
Quantitative Concept
C15710
Nicotine Replacement
C1278444
Nicotine Replacement
Therapy to help control nicotine withdrawal symptoms during tobacco cessation
Therapeutic or Preventive Procedure
Nicotine Replacement
Biological Therapy
owl:Class
Nicotine Replacement
Nicotine Replacement Therapy
NRT
SSCP Analysis
Conformation Dependent Mutation Detection
SSCP Analysis
Single-Strand Conformation Polymorphism Analysis
A procedure used to demonstrate nucleotide sequence variations that occur in the same region of DNA between individuals within a species, or between alleles in an individual to detect mutations in various genes, such as oncogenes, tumor suppressor genes, or genes responsible for genetic diseases. The method detects different conformations adopted by partially denatured DNA fragments resulting from their specific nucleotide sequences under denaturing conditions. Denatured single-stranded DNA fragments are allowed to partially renature without formation of double-stranded DNA. The particular conformations adopted by each of the renatured fragments depend on each of their specific nucleotide sequences. The fragments are run on polyacrylamide gels to detect subtle changes in migration due to their particular secondary structures. Resulting fragment band in the gel will misalign if any point mutations are present to alter the conformation.
CL003144
SSCP Analysis
Laboratory Procedure
SSCP Analysis
owl:Class
C19229
Pulse Radiolysis
Photometry / Spectrum Analysis, Pulse Radiolysis
Research Activity
Physical Chemical Technique
Pulse Radiolysis
Pulse Radiolysis
owl:Class
Pulse Radiolysis is a technique of exposing a sample of material to a beam of highly accelerated electrons to initiate fast reaction events occurring between 10-11 and 102 s after energy absorption. The technique is used to study fast reactions of biologically important molecules, e.g. the kinetics and thermodynamics of redox processes and electron-transfer reactions, enzymatic processes and structural effects which are revealed by physical or kinetic properties.
C0034109
C17044
Laboratory Procedure
Pulse Radiolysis
Retreatment
C0376495
owl:Class
Reintroduction
Retreatment
Readministration
Retreatment
The repeated act of the dispensing, applying, or tendering of something to another after an initial treatment.
Action
C54055
Retreatment
Reapplication
Activity
Endocrine Test
Triiodothyronine Uptake Measurement
CL384428
T3UP
Triiodothyronine Uptake
CDISC SEND Terminology
CDISC
Triiodothyronine Uptake Measurement
CDISC SDTM Terminology
The determination of the binding of triiodothyonine to thyroxine binding globulin protein in a sample.
Triiodothyronine Uptake Measurement
owl:Class
Clinical Data Interchange Standards Consortium Terminology
Protein or Enzyme Type Measurement
C74748
CDISC SDTM Laboratory Test Terminology by Code
<def-source>CDISC</def-source><def-definition>A measurement of the binding of triiodothyonine to thyroxine binding globulin protein in a biological specimen.</def-definition>
Triiodothyronine Uptake Measurement
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Code
CDISC SEND Terminology
Mu Glutathione-S-Transferase to Creatinine Ratio Measurement
Mu Glutathione-S-Transferase to Creatinine Ratio Measurement
Laboratory Procedure
Mu Glutathione-S-Transferase/Creatinine
Urine Protein Measurement
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Terminology
C79458
The determination of the ratio of mu glutathione-s-transferase compared to creatinine present in a sample. The measurement may be expressed as a ratio or percentage.
Mu Glutathione-S-Transferase to Creatinine Ratio Measurement
Mu Glutathione-S-Transferase to Creatinine Ratio Measurement
<def-definition>A relative measurement (ratio or percentage) of the mu gamma glutamyl transpeptidase to creatinine in a biological specimen.</def-definition><def-source>CDISC</def-source>
owl:Class
GSTMUCRT
The determination of the amount of leptin hormone present in a sample.
CDISC SDTM Laboratory Test Terminology by Name
C1295176
Laboratory Procedure
Leptin Measurement
Leptin Measurement
C74866
Clinical Data Interchange Standards Consortium Terminology
CDISC SEND Terminology
LEPTIN
Leptin Measurement
CDISC SDTM Laboratory Test Terminology by Code
<def-definition>A measurement of the leptin hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Terminology
owl:Class
Hormone Measurement
Leptin Measurement
Leptin
Behavioral Treatment
C0004933
Behavioral Intervention
Behavioral Interventions
Behavioral Therapy
Behavior Therapy
Behavior Modification
The use of operant conditioning, including rewards and punishments, in helping a person create an atmosphere where he or she does not contribute to painful stimuli.
Behavioral Intervention
Behavior or Life Style Modifications
Behavior Conditioning Therapy
Behavioral Modification
Behavioral, Psychological or Informational Intervention
owl:Class
Behavioral Intervention
Behavioral Treatments
Behavioral Intervention
C15184
Therapeutic or Preventive Procedure
C81953
owl:Class
The determination of the amount of eotaxin-2 present in a sample.
Eotaxin-2 Measurement
Chemokine Measurement
Eotaxin-2 Measurement
Eotaxin-2 Measurement
Eotaxin-2 Measurement
<def-definition>A measurement of the methaqualone present in a biological specimen.</def-definition><def-source>CDISC</def-source>
Methaqualone Measurement
C0025628
Methaqualone Measurement
CDISC SDTM Terminology
Methaqualone
CNS Depressant Drug Measurement
Laboratory Procedure
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Code
Methaqualone Measurement
C74882
Methaqualone Measurement
CDISC SDTM Laboratory Test Terminology by Name
Clinical Data Interchange Standards Consortium Terminology
The determination of the amount of methaqualone present in a sample.
owl:Class
METHQLDN
Left Hemicolectomy
Surgical removal of the left part of the colon.
Left Colectomy
Left Colectomy
Partial Colectomy
Procedure_Has_Excised_Anatomy only 'Left Colon'
Therapeutic or Preventive Procedure
owl:Class
Left Colectomy
C51624
Left Colectomy
CL354065
Interquartile Range
Non-Parametric Test
CL356679
Interquartile Range
Interquartile Range
Interquartile Range
The difference between the 3d and 1st quartiles is called the interquartile range and it is used as a measure of variability (dispersion).
owl:Class
Quantitative Concept
C53245
Phosphate Measurement
PHOS
owl:Class
Laboratory Procedure
Phosphate Measurement
C64857
Electrolyte Measurement
Clinical Data Interchange Standards Consortium Terminology
Phosphorus
CDISC SDTM Terminology
C0523826
Phosphate Measurement
CDISC SDTM Laboratory Test Terminology by Name
Phosphate
A quantitative measurement of the amount of phosphate present in a sample.
Phosphate Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the phosphate in a biological specimen.</def-definition>
CDISC SDTM Laboratory Test Terminology by Code
CDISC
CDISC SEND Terminology
Absorbance at 280nm
The quantity of 280nm light that is not transmitted through a substance or solution.
Activity
A280
owl:Class
In nucleic acid chemistry, the ratio of absorbance of 280nm frequency light to the absorbance of 260nm frequency light is related to nucleic acid purity.
Molecular Genetic Technique
C48170
OD280
Absorbance at 280nm
Absorbance at 280nm
Absorbance at 280nm
CL342938
CL371685
C67286
Ultrasound-Guided Transbronchial Needle Aspiration
owl:Class
EBUS-TBNA
Ultrasound-Guided Transbronchial Needle Aspiration
Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration
Ultrasound-Guided Transbronchial Needle Aspiration
Ultrasound-Guided Transbronchial Needle Aspiration
Fine-Needle Aspiration
Diagnostic Procedure
Procedure_Has_Partially_Excised_Anatomy only Lung
Collecting
owl:Class
Collection
Collected
Activity
C1516695
C25453
The act of gathering things together; having been brought together in one place.
Action
Collection
Collection
Collection
CL360522
Registry Nomenclature Information System
C60711
owl:Class
An information system, RENI (REgistry Nomenclature Information System) is the extended electronic version of the publications 'International Classification of Rodent Tumours'. The system was initially developed to support the RITA (Registry of Industrial Toxicology Animal-data) project, however, since 1998 it is accessible via the Internet. Besides the nomenclature and diagnostic criteria, RENI contains more than 1,500 histopathological images and for most of the references direct links to the corresponding abstracts in PUBMED are provided. (from RITA)
Cancer Research
Registry Nomenclature Information System
Registry Nomenclature Information System
RENI
Registry Nomenclature Information System
Research Activity
CL001075
Select suitable vaccine candidates and support efficacy trials when appropriate criteria are met.
Phase III Trial
Phase III Large Scale Vaccine Trial
Vaccine Trial-Phase III Large Scale
Research Activity
C15873
Vaccine Clinical Trial
Phase III Large Scale Vaccine Trial
Phase III Large Scale Vaccine Trial
owl:Class
Phase III Large Scale Vaccine Trial
CDISC SDTM Laboratory Test Terminology by Name
The determination of the amount of interleukin 30 present in a sample.
C74828
<def-definition>A measurement of the interleukin 30 in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SEND Terminology
Interleukin 30 Measurement
Cytokine Measurement
Interleukin 30 Measurement
Clinical Data Interchange Standards Consortium Terminology
Laboratory Procedure
CDISC SDTM Terminology
Interleukin 30 Measurement
Interleukin 30 Measurement
CL384309
owl:Class
Interleukin 30
INTLK30
CDISC SDTM Laboratory Test Terminology by Code
Instruction Imperative
Instil
Instill
Instill
CL370439
C64981
Activity
Instill
Instill
owl:Class
soft diet
Diet
Soft Diet
Soft Diet
Soft Diet
C28238
owl:Class
Therapeutic or Preventive Procedure
Soft Diet
<def-source>NCI-GLOSS</def-source><def-definition>A diet consisting of bland foods that are softened by cooking, mashing, pureeing, or blending.</def-definition>
C0301569
Traction
C21119
Traction
Traction
C0040597
Therapeutic Procedure
owl:Class
Therapeutic or Preventive Procedure
Traction
The application of pulling forces to improve functional alignment.
Morphine
CDISC SEND Terminology
MORPHINE
CDISC SDTM Laboratory Test Terminology by Code
Opioid Measurement
CDISC SDTM Terminology
CL384417
Morphine Measurement
C74883
owl:Class
Morphine Measurement
The determination of the amount of morphine present in a sample.
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Name
Morphine Measurement
Laboratory Procedure
Morphine Measurement
<def-definition>A measurement of the morphine present in a biological specimen.</def-definition><def-source>CDISC</def-source>
Activity
Cancel
Cancelation
Cancel
Cancel
C0205544
Cancel
owl:Class
C63471
Canceled
Action
Postpone indefinitely or annul something that was scheduled.
C1135847
Thermal Field-Flow Fractionation
owl:Class
An analytical technique used to separate a multi-component sample by applying a retarding force or gradient to a sample in a solvent stream, which drives the sample toward a thin channel wall. The velocity at which a component leaves the center solvent stream is dependent on its physical characteristics.
FFF
Field Flow Fractionation
Physical Chemical Technique
Field Flow Fractionation
Asymmetrical Flow Field-Flow Fractionation
AFFF
Laboratory Procedure
Sedimentation Field-Flow Fractionation
Field Flow Fractionation
Field-Flow Fractionation
C62321
Field Flow Fractionation
Flow Field-Flow Fractionation
Electrical Field-Flow Fractionation
Structured Product Labeling Terminology
C54346
Dose Modification
owl:Class
Dose Modification
Functional Concept
Dose Modification
Limitation Of Use Structured Product Labeling Terminology
Treatment Regimen
FDA
Dose Modification
CL357252
Change, alteration, or adjustment of a dose specified in a treatment plan or/and administered to a patient.
owl:Class
Thoracic Surgical Procedures
Therapeutic or Preventive Procedure
<def-source>MSH2001</def-source><def-definition>Surgery performed on the thoracic organs, most commonly the lungs and the heart.</def-definition>
C15655
Thoracic Surgical Procedure
Surgical Procedure by Site or System
Thoracic Surgery
Thoracic Surgical Procedure
Procedure_Has_Target_Anatomy only 'Thoracic Cavity'
Chest Surgery
Thoracic Surgical Procedure
C0524832
Thoracic Surgical Procedure
Beta Catenin Staining Method
Beta Catenin Staining Method
Special Histology Staining Method
Beta Catenin Staining Method
BCAT
Beta Catenin
An immunohistochemical technique that uses an anti-beta-catenin monoclonal antibody and subsequent staining by an avidin-biotin complex to immunostain beta-catenin.
Beta Catenin Staining Method
Beta Catenin Staining Method
This technique is useful in detection of colorectal cancer, where beta-catenin is accumulated as a result of APC mutations.
C1527145
Laboratory Procedure
C23024
owl:Class
CL030485
Therapeutic or Preventive Procedure
Interleukin Therapy
Interleukin Therapy
owl:Class
Interleukin Therapy
Cytokine Therapy
C15543
Interleukin Therapy
Pulse Oximetry
Diagnostic Procedure
Pulse Oximetry
Pulse Oximetry
A non-invasive method that provides estimates of arterial oxyhemoglobin saturation by utilizing selected wavelengths of light to determine the saturation of oxyhemoglobin.
Pulse Oximetry
Oxygen Saturation Measurement
C38085
owl:Class
C0034108
Methandrostenolone Measurement
owl:Class
Methandrostenolone Measurement
Methandrostenolone Measurement
C75382
The determination of the amount of methandrostenolone present in a sample.
CL384499
Laboratory Procedure
Steroid Measurement
Methandrostenolone Measurement
Healthcare Activity
C16086
owl:Class
Cancer Intervention
CL008588
Cancer Intervention
Cancer Intervention
Cancer Intervention
Health Care Activity
C82025
Monocyte Chemotactic Protein 1 Measurement
Monocyte Chemotactic Protein 1 Measurement
Protein or Enzyme Type Measurement
Monocyte Chemotactic Protein 1 Measurement
The determination of the amount of monocyte chemotactic protein 1 present in a sample.
Monocyte Chemotactic Protein 1 Measurement
owl:Class
Procedure_Has_Excised_Anatomy only 'Cervical Lymph Node'
C0398395
Neck Dissection
Neck Dissection
Neck Dissection
Neck Dissection
Head and Neck Surgery
Regional Lymph Node Dissection
Therapeutic or Preventive Procedure
Procedure_Has_Target_Anatomy only Neck
<def-source>NCI-GLOSS</def-source><def-definition>(dye-SEK-shun) Surgery to remove lymph nodes and other tissues in the neck.</def-definition>
neck dissection
owl:Class
C15643
A statistical computation dervied by using the expected value and averaging the squared distance of all viable values.
owl:Class
variance
Qualitative Concept
Variance
<def-source>CDISC</def-source><def-definition>A measure of the variability in a sample or population. It is calculated as the mean squared deviation (MSD) of the individual values from their common mean. In calculating the MSD, the divisor n is commonly used for a population variance and the divisor n-1 for a sample variance.</def-definition>
Clinical Data Interchange Standards Consortium Glossary Terminology
Variance
Clinical Data Interchange Standards Consortium Terminology
Statistical Technique
Variance
CL343807
Variance
CDISC
C48918
Adjusted Bonferroni Correction
CL378532
Adjusted Bonferroni Correction
A multiple comparison adjustment method where the p-values are ranked in descending order. For the highest p-value, the critical p-value becomes (alpha/n), where n is the number of outcomes being tested; for the second-highest p-value, the critical p-value will be (alpha/n-1), and so on. The stringency of this correction falls somewhere between no correction and the Standard Bonferroni.
Adjusted Bonferroni
Adjusted Bonferroni Correction
Adjusted Bonferroni Adjustment
Multiple Comparison Adjustment
Adjusted Bonferroni Correction
Adjusted Bonferroni Method
owl:Class
Quantitative Concept
C72534
Laboratory Procedure
CD4LY
CD4/Lymphocytes
Blood Cell Count Ratio Measurement
<def-source>CDISC</def-source><def-definition>A relative measurement (ratio or percentage) of CD4 T cells to all lymphocytes in a biological specimen.</def-definition>
CDISC SDTM Laboratory Test Terminology by Code
CD4 T Cell to Lymphocyte Ratio Measurement
CDISC SDTM Laboratory Test Terminology by Name
Clinical Data Interchange Standards Consortium Terminology
CD4 T Cell to Lymphocyte Ratio Measurement
The determination of the ratio of CD4 T cells compared to lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
CL384377
CDISC
owl:Class
C74638
CD4 T Cell to Lymphocyte Ratio Measurement
CDISC SDTM Terminology
CD4 T Cell to Lymphocyte Ratio Measurement
CDISC SEND Terminology
Techniques and methods for separating cells (usually viable) based on a variety of criteria for separation, such as size or density, non-specific surface properties, or specific surface properties. Examples include cell affinity chromatography and centrifugation using density gradients.
<def-source>CSP2000</def-source><def-definition>applies only to artificial, usually extracorporeal techniques; for natural, in vivo processes, use CELL MIGRATION.</def-definition>
Cell Sorting
Cell Separation Technology
C0007616
Research Technique
Cell Sorting
C16406
Cell Sorting
Cell Sorting
Laboratory Procedure
owl:Class
Daily or Recreational Activity
Strenuous Exercise
C39773
Exercise
Strenuous exercises include jogging, swimming, bicycling, and brisk walking. Maximum heart rate is approximately 220 minus current age in years.
Strenuous Exercise
Strenuous Exercise
Strenuous Activity
20-60 minutes of exercise which elevates your heart rate to 80-90% of your maximum heart rate performed at least 3-4 times per week.
owl:Class
CL323824
Strenuous Exercise
Cancer therapy using ionizing radiation to &lt; 50% of the body.
Limited Radiation Therapy
C54225
Limited Radiation Therapy
CL357283
owl:Class
Radiation Therapy
Limited Radiation Therapy
Therapeutic or Preventive Procedure
Limited Radiation Therapy
Temazepam Measurement
The determination of the amount of temazepam present in a sample.
owl:Class
C1266744
Laboratory Procedure
Temazepam Measurement
Temazepam Measurement
C75376
Benzodiazepine Measurement
Temazepam Measurement
C71579
CL378355
Action
Debug
owl:Class
Activity
Debug
Locate and correct errors in a computer program code.
Debug
Debug
Pregnancy-Associated Plasma Protein-A Measurement
Pregnancy-Associated Plasma Protein-A Measurement
Pregnancy-Associated Plasma Protein-A Measurement
The determination of the amount of pregnancy-associated plasma protein-A present in a sample.
C82031
Protein or Enzyme Type Measurement
owl:Class
Pregnancy-Associated Plasma Protein-A Measurement
owl:Class
Dental Procedure
Pulpectomy
C62550
Pulpectomy
Pulpectomy
C0034102
The complete removal of the dental pulp.
Pulpectomy
Therapeutic or Preventive Procedure
owl:Class
C15765
AIDS, Clinical Trials on Minorities
AIDS, Clinical Trials on Minorities
AIDS Clinical Trial
AIDS clinical trials related to individuals of non-Caucasian descent.
Research Activity
AIDS, Clinical Trials on Minorities
CL000045
AIDS, Clinical Trials on Minorities
Spectroscopy
Fluorescence Spectroscopy
Fluorescence Spectroscopy
Laboratory Procedure
owl:Class
Fluorescence Spectroscopy
Diagnostic Procedure
Fluorescence Spectroscopy
Spectroscopy, Fluorescence
Fluorescent spectroscopy or fluorometry is a type of electromagnetic spectroscopy used for analyzing fluorescent spectra. It involves using a beam of light, usually ultraviolet light, that excites the electrons in molecules of certain compounds and causes them to emit light of a lower energy, typically, but not necessarily, visible light.
C17738
C0242506
CL384727
<def-source>CDISC</def-source><def-definition>A measurement of the blast cells in a biological specimen.</def-definition>
Blast Count
Blast Count
CDISC SEND Terminology
Blood Cell Count
owl:Class
Laboratory Procedure
Blast Count
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Terminology
CDISC
C74605
Blast Count
The determination of the number of blast cells present in a blood sample.
CDISC SDTM Laboratory Test Terminology by Code
Blasts
Clinical Data Interchange Standards Consortium Terminology
BLAST
Sacrifice
Activity
Destroy
C68781
owl:Class
Sacrifice
Action
Sacrifice
Sacrifice
To kill an experimental animal.
Kill
CL370083
Therapeutic or Preventive Procedure
Local Therapy
Low-LET Radiotherapy
Low-LET Radiotherapy
Radiotherapy, Low Linear Energy Transfer
C15850
Radiotherapy using radioactive particles that deposit a low amount of energy by radiation per unit length of travel.
CL000826
Low-LET Radiotherapy
Radiation Therapy
owl:Class
Radiotherapy, Low LET
Low-LET Radiotherapy
The act of increasing (something) in size or volume or quantity or scope.
Enlargement
owl:Class
Enlarged
Activity
C73432
Enlargement
Enlargement
CL383415
Enlargement
Action
Clinical Study by Phase
CDISC SDTM Terminology
owl:Class
1-2
CL031847
Research Activity
<def-source>NCI-GLOSS</def-source><def-definition>A trial to study the safety, dosage levels, and response to a new treatment.</def-definition>
Phase I/II Trial
CDISC
Phase I/II trial
Phase I/II Trial
A clinical research protocol designed to study the safety, dosage levels and response to new treatment. Phase I/II trials combine a Phase I and a Phase II trial of the same treatment into a single protocol.
Phase I/II Trial
CDISC SDTM Trial Phase Terminology
Phase I/II Trial
Trial Phase 1-2
C15693
Trial Phase 1/2
Clinical Data Interchange Standards Consortium Terminology
<def-source>CDISC</def-source><def-definition>A class of clinical study that combines elements characteristic of traditional Phase I and Phase II trials. See also Phase I, Phase II.</def-definition>
Take
Take
C65105
Take
C1515187
owl:Class
Activity
Take
Instruction Imperative
Diagnostic Endoscopic Procedure
C64940
Diagnostic Procedure
Diagnostic Endoscopic Procedure
CL370141
Diagnostic Endoscopic Procedure
owl:Class
Diagnostic Procedure
Endoscopic Procedure
Diagnostic Endoscopic Procedure
Mean Criterion
C64228
Method for removing extreme values from a set, based upon its deviation from the mean. Defined in documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html
owl:Class
Mean Criterion
Remove Extremes
Mean Criterion
Mean Criterion
CL369361
Activity
Synthetic
Synthesized
C61408
Synthesis
Synthesis
The process of producing a chemical compound, usually by the union of simpler chemical compounds.
Activity
CL364259
owl:Class
Synthesis
Synthesis
Action
Removal of tumor cells from the graft.
Tumor Purging
Tumor Purging
Health Care Activity
Tumor Purging
Tumor Purging
owl:Class
C70600
CL376060
Therapeutic Procedure
Therapeutic or Preventive Procedure
owl:Class
High-Dose Chemotherapy with Stem Cell Support
High-Dose Chemotherapy with Stem Cell Support
High-Dose Chemotherapy with Stem Cell Support
HDC/ASCT
High-Dose Chemotherapy with Autologous Stem Cell Transplant
C1512429
High Dose Chemotherapy
High-Dose Chemotherapy with Stem Cell Support
C38722
Mind-Body Intervention Procedure
CL353537
Complementary or Alternative Medical Procedure
Therapeutic or Preventive Procedure
owl:Class
Mind-Body Intervention Procedure
Mind-Body Interventions
Mind-Body Intervention Procedure
Mind-Body Intervention Procedure
Mind-Body Medicine
C15436
CL365137
C62606
Characterization
Characterized
Activity
Characterization
Action
Characterization
owl:Class
The act of describing distinctive characteristics or essential features.
Characterization
Bioconductor caAffy Loess Normalization
CL369466
A method to normalize Affymetrix arrays using loess, as defined in documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html
Statistical Technique
Activity
Bioconductor caAffy Loess Normalization
Bioconductor caAffy Loess Normalization
Bioconductor caAffy Loess Normalization
owl:Class
C63933
Prior Oophorectomy
Prior Oophorectomy
Prior Oophorectomy
C15499
Prior Therapy
CL029654
Prior Oophorectomy
owl:Class
Clinical Attribute
C82007
The determination of the amount of CD40 ligand present in a sample.
owl:Class
CD40 Ligand Measurement
CD40 Ligand Measurement
Protein or Enzyme Type Measurement
CD40 Ligand Measurement
CD40 Ligand Measurement
Whole-Body Scintigraphy
owl:Class
CL004833
Radionuclide Imaging
Diagnostic Procedure
Whole-Body Scintigraphy
Whole-Body Scintigraphy
A diagnostic technique which produces a two- dimensional image of a desired anatomical structure or region with the use of radionuclides.
C19565
Whole-Body Scintigraphy
Renal Function Test
owl:Class
Renal Function Test
Renal Function Test
A laboratory procedure that evaluates the kidney function.
C0022662
Chemistry Test
Renal Function Test
Laboratory Procedure
C74972
Write
CL384215
Write
owl:Class
Write
C73994
Communicate or express by means of letters or symbols written or imprinted on a surface to represent the sounds or words of a language; record data on a computer.
Write
Action
Activity
Tobacco Smoking
Individual Behavior
Inhaling smoke from tobacco in the form of a cigarette.
CL385081
Cigarette Smoking
owl:Class
Cigarette Smoking
Cigarette Smoking
C18270
Cigarette Smoking
C51680
Therapeutic or Preventive Procedure
Wedge Resection of Tongue
Partial Excision of Tongue
Wedge Resection of Tongue
owl:Class
CL356158
Wedge Resection of Tongue
Surgery involving removal of a wedge-shaped portion of the tongue.
Wedge Resection of Tongue
Behavioral Research
Behavioral Research
Research Activity
owl:Class
C0004939
Behavioral Research
C15185
Behavioral Research
Studies of the motivating factors that influence health practices as well as efforts to modify these practices.
Research Activity
CL008517
Marker Discovery
Marker Discovery
Marker Discovery
Biomedical Research
owl:Class
Activity
Marker Discovery
C16082
Strategies and technologies for molecular phenotyping and biological marker discovery to improve understanding of disease and aid the pharmaceutical industry's ability to develop new therapeutic products efficiently and cost effectively.
CL101511
C25598
Observation
Observation
Observational
owl:Class
Diagnostic Procedure
Observation
Observation
Watching something and taking note of what happens.
Activity
Electrocardiography
C0013798
A procedure which records the electrical current in the heart in the form of a continuous strip graph. The electrocardiography results may determine whether the heart is performing normally or suffering from abnormalities, may indicate coronary artery blockages, can be used for detecting calcium, magnesium and other electrolyte disturbances, allow the detection of conduction abnormalities, indicate the physical shape of a patient during stress test and provide information on the physical condition of the heart.
Electrocardiography
Electrocardiography
Cardiac Diagnostic Procedure
C38053
Electrocardiography
Diagnostic Procedure
owl:Class
ECG
EKG
CL356370
owl:Class
State Level Statistic
State Level Statistic
Quantitative Concept
State Level Statistic
Geographic Area Level Statistic
State Level Statistic
C53187
owl:Class
Nephrectomy
Partial Nephrectomy
Therapeutic or Preventive Procedure
<def-source>NCI-GLOSS</def-source><def-definition>Surgery to remove part of one kidney or a kidney tumor, but not an entire kidney.</def-definition>
Partial Nephrectomy
Procedure_Has_Partially_Excised_Anatomy only Kidney
Partial Nephrectomy
Partial Nephrectomy
C51928
partial nephrectomy
CL354140
Laboratory Procedure
Fiber FISH
Fiber FISH
C19573
owl:Class
Fiber FISH
CL004875
Molecular Biology Research Technique
Fluorescent in situ hybridization performed on uncondensed DNA strands. Due to the extended nature of the target DNA this procedure provides greater sensitivity for mapping closely situated markers.
Fluorescence in situ Hybridization
Fiber FISH
Head and Neck Surgery
owl:Class
Procedure_Has_Excised_Anatomy only Pharynx
Pharyngectomy
Surgery involving the complete or partial excision of the pharynx.
Pharyngectomy
Therapeutic or Preventive Procedure
Pharyngectomy
C51608
CL354157
Pharyngectomy
owl:Class
<def-source>NCI-GLOSS</def-source><def-definition>Treatment that affects cells in the tumor and the area close to it.</def-definition>
Localized Therapy
CL031829
C15687
Therapeutic Procedure
Local Therapy
Therapeutic or Preventive Procedure
Local Therapy
Local Therapy
local therapy
Local Therapy
C60719
Permanent Dental Restoration
Permanent Dental Restoration
Dental Restoration
C0011413
Final Dental Restoration
Permanent Dental Restoration
Therapeutic or Preventive Procedure
owl:Class
Permanent Dental Restoration
A replacement for a lost tooth structure designed for continued or prolonged use.
C51306
CL355082
Educational Activity
Activity
Educational Activity
Educational Activity
Educational Activity
Educational Activity
owl:Class
The activities of educating or instructing or teaching; activities that impart knowledge or skill.
CL356248
Research Activity
Biased Estimation
Statistical Estimation
Biased Estimation
owl:Class
C53328
Biased Estimation
Biased Estimation
Prior Biologic Therapy
C15452
owl:Class
Clinical Attribute
Prior Biologic Therapy
CL029116
Prior Biologic Therapy
Prior Biologic Therapy
Prior Therapy
C64831
Neutrophil Band Form to Leukocyte Ratio
CDISC SEND Terminology
CDISC SDTM Terminology
Neutrophils Band Form/Leukocytes
CDISC SDTM Laboratory Test Terminology by Name
Clinical Data Interchange Standards Consortium Terminology
Neutrophil Band Form to Leukocyte Ratio
CL370307
Blood Cell Count Ratio Measurement
Neutrophil Band Form to Leukocyte Ratio
The determination of the ratio of band neutrophils compared to leukocytes in a blood sample. The measurement may be expressed as a ratio or percentage.
owl:Class
<def-definition>A relative measurement (ratio or percentage) of the banded neutrophils to leukocytes in a biological specimen.</def-definition><def-source>CDISC</def-source>
Laboratory Procedure
NEUTBLE
CDISC SDTM Laboratory Test Terminology by Code
CDISC
Neutrophil Band Form to Leukocyte Ratio
Biopsy of Lip
Biopsy of Lip
Biopsy of Lip
Diagnostic Procedure
C51653
Procedure_Has_Partially_Excised_Anatomy only Lip
owl:Class
Removal of tissue from the lip for microscopic examination.
CL354995
Biopsy
Biopsy of Lip
EDDP Measurement
The determination of the amount of EDDP, the primary metabolite of methadone, present in a sample.
EDDP Measurement
owl:Class
Methadone Measurement
2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine Measurement
EDDP Measurement
EDDP Measurement
CL384485
Laboratory Procedure
C75353
CL370079
owl:Class
C76322
The process of applying a solvent (e.g., water) or a solution (e.g., SSC/SDS) to a biomaterial or an array to remove impurities or unwanted compounds.
Wash
Cell Wash
Cell Wash
Wash
Cell Wash
Cell Wash
Activity
Tumor Necrosis Factor Therapy
Tumor Necrosis Factor Therapy
owl:Class
Tumor Necrosis Factor Therapy
Therapeutic or Preventive Procedure
CL029723
Cytokine Therapy
C15507
Tumor Necrosis Factor Therapy
Sympathetic Block
Therapeutic or Preventive Procedure
Neural Block
Sympathetic Block
Sympathetic Block
C0039043
Sympathetic Neural Blockade
owl:Class
Sympathetic Block
Neural blockade of the sympathetic nerve roots.
Sympathetic Neural Block
C21110
Procedure_Has_Excised_Anatomy only 'Right Fallopian Tube'
Surgery to remove part or all of the right fallopian tube.
C51606
Therapeutic or Preventive Procedure
Right Salpingectomy
Right Salpingectomy
Right Salpingectomy
CL355473
owl:Class
Salpingectomy
Right Salpingectomy
CL375941
Bone Metastases Treatment
Therapeutic or Preventive Procedure
owl:Class
C70812
Cancer Therapeutic Procedure
Bone Metastases Treatment
Bone Metastases Treatment
Bone Metastases Treatment
owl:Class
Clinical Study by Design
Clinical Study by Design
CL375963
Clinical Study by Design
Clinical Study by Design
C70821
Clinical Trial
Research Activity
C25498
C0680844
Estimate
Estimation
Action
owl:Class
Activity
Estimated
Estimate
Estimate
To calculate approximately.
Estimate
C65076
Activity
Cleansed
Clean
Clean
CL370633
Clean
Instruction Imperative
Cleanse
The action of removing dirt, filth, or unwanted substances from.
owl:Class
Cleaned
Clean
Tobacco Use and Related Risk Factors, Surveillance
Tobacco Use and Related Risk Factors, Surveillance
Tobacco Use and Related Risk Factors, Surveillance
CL003966
Health Care Activity
Tobacco Use and Related Risk Factors, Surveillance
C15987
Cancer Surveillance Project
owl:Class
Research studies that assess trends in tobacco-related risk factors, behaviors and health services to determine changes over time and the influence of these trends on cancer incidence, morbidity, mortality and survival. (NCI/TRIP)
Cordectomy
C28353
cordectomy
owl:Class
Cordectomy
Cordectomy
CL074552
Therapeutic or Preventive Procedure
Cordectomy
Surgical Procedure by Method
<def-source>NCI-GLOSS</def-source><def-definition>(kor-DEK-tuh-mee) An operation on the vocal cords or on the spinal cord.</def-definition>
C64914
Instruction Imperative
Shift the position or location of; take out of.
owl:Class
Remove
CL370493
Activity
Remove
Remove
Remove
Research Activity
owl:Class
An assay based on Antibody-Dependent Cellular Cytotoxicity, which involves the killing of a target cell by a killer cell. This is accomplished via an antibody directed to the target by the antigen-binding arms and anchored to the killer cell via an Fc receptor.
ADCC Assay
Laboratory Procedure
ADCC Assay
C15414
ADCC Assay
C0201624
ADCC Assay
Cellular Assay
Preventive Intervention
CL000755
Preventive Intervention
Preventive Intervention
Prophylaxis
Prevention Measures
owl:Class
<def-source>NCI-GLOSS</def-source><def-definition>An attempt to prevent disease.</def-definition>
Therapeutic, nutritional, environmental, social and or behavioral interventions at the societal, community, organizational or individual levels to reduce, modify or stop the course of a disease.
prophylaxis
C15843
Preventive Intervention
Prevention
Therapeutic or Preventive Procedure
Intervention or Procedure
CDISC SEND Terminology
Laboratory Procedure
owl:Class
CDISC
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
Urine Sediment Analysis Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the bacterial casts present in a urine specimen.</def-definition>
C74762
Bacterial Casts
Bacterial Cast Measurement
Bacterial Cast Measurement
Bacterial Cast Measurement
CDISC SDTM Terminology
CSBACT
CL384754
CDISC SDTM Laboratory Test Terminology by Name
The determination of the amount of bacterial casts present in a urine sample.
Bacterial Cast Measurement
Disassembly
Disassembly
Activity
owl:Class
Disassembly
C52475
Action
Disassembly
Disassemble
The act of taking something apart; to come apart.
CL355704
C0376547
Aromatherapy and Essential Oils
Aromatherapy and Essential Oils
Mind-Body Intervention Procedure
Aromatherapy
owl:Class
Aromatherapy and Essential Oils
Therapeutic or Preventive Procedure
The use of fragrant essences or extracts from plants to treat a variety of health conditions and support and balance the mind, body, and spirit.
Aromatherapy and Essential Oils
C62681
C39564
<def-source>CDISC</def-source><def-definition>A clinical encounter that encompasses planned and unplanned trial interventions, procedures and assessments that may be performed on a subject. A visit has a start and an end, each described with a rule. NOTE: For many domains each visit results in one record per visit. [SDTM, Trial Design Model]</def-definition>
Health Care Visit
owl:Class
Health Care Visit
A visit by a patient or study participant to a medical professional.
Clinical Data Interchange Standards Consortium Glossary Terminology
Clinical Data Interchange Standards Consortium Terminology
Health Care Visit
Visit
Healthcare Visit
CL323657
CDISC
Individual Behavior
Health Care Visit
visit
Glycosylated Hemoglobin Measurement
CDISC SEND Terminology
Glycosylated Hemoglobin Measurement
Laboratory Procedure
Glycosylated Hemoglobin Measurement
HBA1C
<def-source>CDISC</def-source><def-definition>A measurement of the glycosylated hemoglobin in a biological specimen.</def-definition>
CDISC SDTM Laboratory Test Terminology by Code
C64849
CDISC
CDISC SDTM Laboratory Test Terminology by Name
A quantitative measurement of the amount of glycosylated hemoglobin present in a sample of blood.
Hemoglobin A1C
Glycosylated Hemoglobin Measurement
C0202054
owl:Class
Hemoglobin Measurement
CDISC SDTM Terminology
Clinical Data Interchange Standards Consortium Terminology
A difference cloning method and a technique for comparison of two closely related cell types, e.g. a differentiated or transformed cell (tester) and the undifferentiated or normal cell (driver). Driver RNA is converted to double-strand cDNA, usually with the incorporation of a tagged nucleotide, while the tester RNA is converted to first-strand cDNA (with no tag). The two preparations are mixed, melted and annealed to form, among other species, heteroduplexes composed of one strand from each of the different sources. The annealed heteroduplexes, as well as other driver species are captured by the tagged nucleotide and removed from the mixture. The resulting pool will be enriched for those cDNA species unique to the tester cells. Following second-strand synthesis, the double-stranded cDNAs are cloned. The resulting cDNA library will be enriched for sequences expressed only in the tester cells. cDNA subtraction can also be done by PCR. (NCI/OSP)
owl:Class
Molecular Genetic Technique
CL000181
cDNA Subtraction
Molecular Biology Research Technique
cDNA Subtraction
C18686
cDNA Subtraction
cDNA Subtraction
Ligation
Ligation
ligation
Closure by Ligation
<def-source>MSH2001</def-source><def-definition>Application of a ligature to tie a vessel or strangulate a part.</def-definition>
Therapeutic or Preventive Procedure
owl:Class
Surgical Procedure by Method
C15270
Ligation
<def-source>NCI-GLOSS</def-source><def-definition>(lye-GAY-shun) The process of tying off blood vessels so that blood cannot flow to a part of the body or to a tumor.</def-definition>
Ligation
C0023690
owl:Class
Serum Creatinine Measurement
Laboratory Procedure
Serum Creatinine Measurement
C0201976
Renal Function Test
A quantitative measurement of the amount of creatinine present in a sample of serum.
Serum Creatinine Measurement
Serum Chemistry Measurement
Serum Creatinine Measurement
C61023
A laboratory test of biological material such as blood, urine, hair, saliva or sweat, used to detect the presence of a drug or its metabolites with in the body.
Drug Test
owl:Class
Chemistry Test
Drug Test
Laboratory Procedure
Drug Test
C0373483
C78139
Drug Test
Drug Screen
Trace Element Nutrition, Selenium
Role of selenium in cancer causation or prevention and in general health.
Research Activity
Trace Element Nutrition, Selenium
C16017
Nutrition, Trace Elements
owl:Class
Trace Element Nutrition, Selenium
CL004460
Trace Element Nutrition, Selenium
Nutrition, Selenium
Locator Parameter
C53315
Locator Parameter
Locator Parameter
Quantitative Concept
Statistical Distribution Characteristic
owl:Class
Locator Parameter
CL356293
Neoplastic Disease and Pregnancy
Research Activity
CL010528
Neoplastic Disease and Pregnancy
Neoplastic Disease and Pregnancy
Maternal and Child Health Study
C16121
Neoplastic Disease and Pregnancy
owl:Class
CL354449
Biopsy of Palate
Procedure_Has_Partially_Excised_Anatomy only 'Soft Palate'
C51585
Diagnostic Procedure
Biopsy of Soft Palate
Biopsy of Soft Palate
Biopsy of Soft Palate
Biopsy of Soft Palate
owl:Class
Removal of tissue from the soft palate for microscopic examination.
The value which occurs most often in a set of values. If no value is repeated, there is no mode. If more than one value occurs with the same greatest frequency, each value is a mode.
CDISC
<def-source>CDISC</def-source><def-definition>The most frequently occurring value in a data set.</def-definition>
mode
Mode
Mode
Mode
Mode
Clinical Data Interchange Standards Consortium Glossary Terminology
C1513371
Statistical Mode
owl:Class
C53320
Quantitative Concept
Measure of Central Tendency
Marker Network for Bladder Cancer
Research Activity
Marker Network for Bladder Cancer
owl:Class
CL008235
Cancer Research
The goal of the network is to evaluate biochemical, immunologic, genetic, and other quantifiable markers for diagnosis and prognosis of urinary bladder cancer.
C16073
Marker Network for Bladder Cancer
Marker Network for Bladder Cancer
C49658
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Trial Summary Parameter Terminology by Name
Trial Blinding Schema
<def-source>CDISC</def-source><def-definition>The name of a code list that contains terms to define the type of blinding for the trial. (NCI)</def-definition>
owl:Class
Trial Blinding Schema
TBLIND
CDISC SDTM Terminology
Research Activity
CDISC
C1710473
Trial Blinding Schema
Study Design
Trial Blinding Schema
The name of a code list that contains terms to define the type of blinding that is used for the trial.
CDISC SDTM Trial Summary Parameter Terminology by Code
Blinding Schema
C0205540
Approval
Acceptance as satisfactory by an authoritative body; established by authority; given authoritative approval.
Action
Approved
Approval
Approve
Activity
Approval
C25425
owl:Class
Approval
Conduct clinical trials and develop new trial methodologies. Trials should be designed in order to rapidly develop new therapeutic strategies, optimize clinical efficacy and proper use of available modalities, define factors that affect the success of therapeutic strategies (including the role of resistance), and advance our understanding of disease pathogenesis and progression.
owl:Class
Activity
Conduct Clinical Trials
Conduct Clinical Trials
Conduct Clinical Trials
CL000258
Administrative Activity
C15793
Conduct Clinical Trials
Left Reduction Mammoplasty
CL353515
Left Reduction Mammoplasty
Therapeutic or Preventive Procedure
Surgery performed to reduce the size of the left breast.
owl:Class
Left Reduction Mammoplasty
Left Reduction Mammoplasty
Procedure_Has_Partially_Excised_Anatomy only 'Left Breast'
Reduction Mammoplasty
C51617
ER+
C15492
Estrogen Receptor Status
owl:Class
C0279754
Positive Estrogen Receptor
estrogen receptor positive
Estrogen Receptor Positive
Clinical Attribute
Estrogen Receptor Positive
Estrogen Receptor Positive
<def-source>NCI-GLOSS</def-source><def-definition>Breast cancer cells that have a protein (receptor molecule) to which estrogen will attach. Breast cancer cells that are ER+ need the hormone estrogen to grow and will usually respond to hormone (antiestrogen) therapy that blocks these receptor sites.</def-definition>
Estrogen Receptor Positive
Modified Radical Mastectomy
<def-source>NCI-GLOSS</def-source><def-definition>(mas-TEK-toe-mee) Surgery for breast cancer in which the breast, some of the lymph nodes under the arm, the lining over the chest muscles, and sometimes part of the chest wall muscles are removed.</def-definition>
Procedure_Has_Completely_Excised_Anatomy only Breast
Modified Mastectomy
Procedure_May_Have_Excised_Anatomy some 'Axillary Lymph Node'
modified radical mastectomy
Procedure_Has_Completely_Excised_Anatomy only Nipple
Procedure_Has_Completely_Excised_Anatomy only 'Mammary Gland'
Modified Radical Mastectomy
Modified Radical Mastectomy
owl:Class
C0024883
C15278
Procedure_Has_Completely_Excised_Anatomy only Areola
Mastectomy
Therapeutic or Preventive Procedure
Modified Radical Mastectomy
C15769
owl:Class
Basic Behavioral and Social Science Research
Basic social sciences and behavioral research designed to strengthen the understanding of (a) the determinants and processes that influence HIV-related risk behaviors and (b) the consequences of HIV disease.
Behavioral Research
Basic Behavioral and Social Science Research
Basic Behavioral and Social Science Research
Research Activity
Basic Behavioral and Social Science Research
CL000084
UVA Light Therapy
UVA Light Therapy
UVA Light Therapy
UVA Light Therapy
C0454529
C16228
owl:Class
Light therapy using ultraviolet radiation between 320 to 400 nm.
Therapeutic or Preventive Procedure
UV Light Therapy
Agent Dose Tapered
Agent Dose Tapered
Dose Modification
owl:Class
Functional Concept
C70891
Agent Dose Tapered
CL375930
Agent Dose Tapered
CL378121
owl:Class
Sampling Method
Independent Sampling
Independent Sampling
C71518
Independent Sampling
Quantitative Concept
Independent Sampling
owl:Class
CDISC SEND Terminology
CDISC SDTM Terminology
C74818
CDISC SDTM Laboratory Test Terminology by Name
Clinical Data Interchange Standards Consortium Terminology
The determination of the amount of interleukin 21 present in a sample.
INTLK21
Interleukin 21 Measurement
<def-definition>A measurement of the interleukin 21 in a biological specimen.</def-definition><def-source>CDISC</def-source>
Interleukin 21 Measurement
CL384299
Interleukin 21 Measurement
Cytokine Measurement
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Code
Interleukin 21
Interleukin 21 Measurement
C0202418
C74881
Methadone Measurement
owl:Class
Clinical Data Interchange Standards Consortium Terminology
<def-definition>A measurement of the methadone present in a biological specimen.</def-definition><def-source>CDISC</def-source>
Methadone Measurement
CDISC SDTM Terminology
Methadone
Laboratory Procedure
Opioid Measurement
Methadone Measurement
CDISC SDTM Laboratory Test Terminology by Code
METHDN
Methadone Measurement
CDISC SEND Terminology
The determination of the amount of methadone present in a sample.
CDISC SDTM Laboratory Test Terminology by Name
Glutamate Dehydrogenase
Glutamate Dehydrogenase Measurement
Laboratory Procedure
Clinical Data Interchange Standards Consortium Terminology
C79448
CDISC SEND Terminology
Glutamate Dehydrogenase Measurement
owl:Class
Protein or Enzyme Type Measurement
Glutamate Dehydrogenase Measurement
<def-definition>A measurement of the glutamate dehydrogenase in a biological specimen.</def-definition><def-source>CDISC</def-source>
The determination of the amount of glutamate dehydrogenase present in a sample.
CDISC SDTM Laboratory Test Terminology by Name
Glutamate Dehydrogenase Measurement
CDISC SDTM Laboratory Test Terminology by Code
GLDH
CDISC SDTM Terminology
DNA-Mediated Gene Transfer
CL005619
DNA-Mediated Gene Transfer
owl:Class
C19585
DNA-Mediated Gene Transfer
Gene Transfer
Molecular Biology Research Technique
Introduction of naked DNA into cells by various methods.
DNA-Mediated Gene Transfer
C16081
Laboratory Sensitivity
Qualitative Concept
CL102250
Laboratory Sensitivity
Clinical Testing
Laboratory Sensitivity
owl:Class
Laboratory Sensitivity
Carcinogenicity Test
<def-source>MSH2001</def-source><def-definition>Tests to experimentally measure the tumor-producing/cancer cell-producing potency of an agent by administering the agent (e.g., benzanthracenes) and observing the quantity of tumors or the cell transformation developed over a given period of time. The carcinogenicity value is usually measured as milligrams of agent administered per tumor developed. Though this test differs from the DNA-repair and bacterial microsome MUTAGENICITY TESTS, researchers often attempt to correlate the finding of carcinogenicity values and mutagenicity values.</def-definition>
Carcinogenicity Test
C15196
owl:Class
C0007089
Diagnostic Procedure
Carcinogen Screening
Carcinogenicity Test
Research Activity
Carcinogenicity Test
Manufacturing Product Defect Manufacturing Defect Safety
Manufacturing Product Defect Manufacturing Defect Safety
Regulatory Assessment
Intellectual Product
Manufacturing Product Defect Manufacturing Defect Safety
MANUFACTURING/PRODUCT DEFECT MANUFACTURING DEFECT (SAFETY)
owl:Class
C82459
Manufacturing Product Defect Manufacturing Defect Safety
Isotope-Coded Affinity Tag Analysis
Physical Chemical Technique
CL357697
ICAT
C54164
Isotope-Coded Affinity Tag Protein Analysis
Isotope-Coded Affinity Tag Protein Analysis
Isotope-Coded Affinity Tag Protein Analysis
owl:Class
ICAT Profiling
Isotope-Coded Affinity Tag Protein Analysis
Recognizing that only a single tryptic peptide is needed to quantify the expression of the corresponding parent protein, the ICAT reagent was designed to affinity isolate and quantify via the use of a stable isotope the relative concentrations of cysteine-containing tryptic peptides obtained from digests of control versus experimental samples. A feature of the ICAT approach is that the in vitro incorporation of a stable isotope into one of the two samples being compared obviates the need to analyze by mass spectrometry the control and experimental samples separately. ICAT data, which is analogous to that obtained via the use of two different fluorescent dyes in DNA microarray analysis of mRNA or DIGE analysis of protein expression, provides the corresponding ratio for the level of expression of the parent protein in the control versus experimental sample.
Research Activity
ICAT Analysis
CDISC
Fatty Cast Measurement
Urine Sediment Analysis Measurement
C74766
The determination of the amount of fatty casts present in a urine sample.
Fatty Cast Measurement
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
CL384389
Clinical Data Interchange Standards Consortium Terminology
Fatty Casts
owl:Class
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Terminology
Fatty Cast Measurement
CSFAT
<def-source>CDISC</def-source><def-definition>A measurement of the fatty casts present in a urine specimen.</def-definition>
Fatty Cast Measurement
C53199
Random Number Table Sampling
Random Sampling
Random Number Table Sampling
CL356365
Random Number Table Sampling
Random Number Table Sampling
owl:Class
Quantitative Concept
Benjamini and Hochberg Method
Benjamini-Hochberg Procedure
Benjamini-Hochberg Method
Benjamini-Hochberg Procedure
Benjamini-Hochberg Procedure
C61596
Benjamini-Hochberg Adjustment
Benjamini-Hochberg Procedure
owl:Class
Benjamini and Hochberg Adjustment
A sequential p-value procedure that controls expected false discovery rate.
Quantitative Concept
Benjamini and Hochberg Procedure
CL364477
Multiple Comparison Adjustment
C0202025
FRUCT
owl:Class
Clinical Data Interchange Standards Consortium Terminology
Fructosamine Measurement
Fructosamine Measurement
CDISC SEND Terminology
The determination of the amount of fructosamine present in a sample.
Chemistry Test
<def-source>CDISC</def-source><def-definition>A measurement of the fructosamine in a biological specimen.</def-definition>
CDISC
C74678
Fructosamine Measurement
CDISC SDTM Laboratory Test Terminology by Name
Fructosamine Measurement
Glycated Serum Protein
CDISC SDTM Terminology
Fructosamine
CDISC SDTM Laboratory Test Terminology by Code
Laboratory Procedure
C18881
Nucleic Acid Sequencing
Laboratory Procedure
Molecular Biology, Nucleic Acid Sequencing
owl:Class
Nucleic Acid Sequencing
Nucleic Acid Sequencing
Nucleic Acid Sequencing
C1294197
Gene Sequencing
DNA Analysis
Molecular Biology Research Technique
The process of determining the sequence of purines and pyrimidines in nucleic acids and polynucleotides.
Creatine Kinase BB Measurement
CDISC SDTM Laboratory Test Terminology by Code
CDISC
Laboratory Procedure
Creatine Kinase BB
C64490
CKBB
CDISC SDTM Terminology
Creatine Kinase BB Measurement
A quantitative measurement of the amount of homozygous B-type creatine kinase present in a sample.
Creatine Kinase BB Measurement
CDISC SEND Terminology
Creatine Kinase BB Measurement
Creatine Kinase Measurement
CDISC SDTM Laboratory Test Terminology by Name
CL370580
Clinical Data Interchange Standards Consortium Terminology
<def-source>CDISC</def-source><def-definition>A measurement of the homozygous B-type creatine kinase in a biological specimen.</def-definition>
owl:Class
CDISC SDTM Terminology
Vitamin K
CDISC SDTM Laboratory Test Terminology by Code
Vitamin K Measurement
VITK
Vitamin Measurement
C74907
Vitamin K Measurement
CDISC SEND Terminology
The determination of the amount of Vitamin K present in a sample.
Vitamin K Measurement
Clinical Data Interchange Standards Consortium Terminology
C0042879
Vitamin K Measurement
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Name
Naphthoquinone
<def-definition>A measurement of the Vitamin K in a biological specimen.</def-definition><def-source>CDISC</def-source>
owl:Class
C38082
owl:Class
Pulmonary Function Test
Inspired Oxygen Fraction Test
Pulmonary Function Test/ Inspired Oxygen Fraction
Inspired Oxygen Fraction Test
CL322430
Inspired Oxygen Fraction Test
PFT/FIO2
Diagnostic Procedure
A test to evaluate amount of oxygen taken up by arterial blood and expressed as a fraction of total oxygen of inspired air. This test may include other test such as pulse oximetry for the measurement of arterial blood oxygen levels.
Inspired Oxygen Fraction Test
Research Activity
C15802
Research Activity
Drug Discovery
CL000334
Drug Discovery
Drug Discovery
owl:Class
Drug Discovery
Therapeutic or Preventive Procedure
Complementary or Alternative Medical Procedure
C51976
CAM Therapy
Intervention or Procedure
Complementary and Alternative Medical Procedure
Complementary or Alternative Medical Procedure
CL353824
CAM Procedure
owl:Class
Complementary or Alternative Medical Procedure
Complementary and Alternative Medical Therapy
Complementary or Alternative Medical Procedure
Complementary or Alternative Medical Therapy
Total Hysterectomy
Total Abdominal Hysterectomy
Total Abdominal Hysterectomy
owl:Class
Therapeutic or Preventive Procedure
Abdominal Hysterectomy
Total Abdominal Hysterectomy
Surgical removal of all of the uterus, via an abdominal approach.
CL354832
Total Abdominal Hysterectomy
C51695
Liposome-Mediated Gene Transfer
Encapsulation of DNA within a lipid bilayer with subsequent introduction into a cell by fusion of the liposome with the cell membrane.
Liposome-Mediated Gene Transfer
owl:Class
Gene Transfer
Molecular Biology Research Technique
Liposome-Mediated Gene Transfer
Liposome-Mediated Gene Transfer
C19586
CL005620
C1295184
CDISC SDTM Laboratory Test Terminology by Name
Melatonin Measurement
Laboratory Procedure
Melatonin Measurement
owl:Class
Melatonin Measurement
MLATONIN
C74867
Clinical Data Interchange Standards Consortium Terminology
Melatonin Measurement
CDISC SDTM Laboratory Test Terminology by Code
<def-definition>A measurement of the melatonin hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SEND Terminology
Melatonin
Hormone Measurement
CDISC SDTM Terminology
The determination of the amount of melatonin hormone present in a sample.
Laboratory Procedure
owl:Class
Oncotype DX
A diagnostic assay that quantifies the likelihood of breast cancer recurrence in women with newly diagnosed, early stage breast cancer. In addition to predicting distant disease recurrence, Oncotype DX also assesses the benefit from certain types of chemotherapy. The assay, performed using formalin-fixed, paraffin-embedded tumor tissue, analyzes the expression of a panel of 21 genes and the results are provided as a Recurrence Score (0-100). The gene panel was selected and the Recurrence Score calculation was derived through extensive laboratory testing and multiple independent clinical development studies. Oncotype DX is validated for use in breast cancer patients whose disease is newly diagnosed, stage I or II, node-negative, estrogen receptor-positive and who will be treated with tamoxifen.
C52159
Oncotype DX Breast Cancer Assay
Diagnostic Procedure
Oncotype DX Breast Cancer Assay
Oncotype DX Breast Cancer Assay
CL354753
Histologic Test
Oncotype DX Breast Cancer Assay
TTA System
Expression Technologies for DNA and RNA
TTA System
Tetracycline controlled transactivator (tTA). The original description of a tetracycline-regulated gene expression system is based on two plasmids, one of which constitutively expresses a tetracycline-controlled transactivator protein (tTA), a fusion protein between the tetracycline repressor of E. coli and the transcriptional activation domain of the VP16 protein of herpes simplex virus. The second plasmid contains the gene to be regulated by tTA under the control of an inducible promoter which consists of seven copies of the tetracycline resistance operator (tetO). Since this original description, many modifications have been described. (from Gallia GL, Khalili K. Oncogene 1998. 16:1879-84)
C19092
Molecular Biology Research Technique
TTA System
CL001029
owl:Class
TTA System
Diagnostic Procedure
Screening for Oral Cancer
early detection for oral cancer
oral cancer screening
Screening for Oral Cancer
oral cancer early detection
owl:Class
C15548
Screening for Oral Cancer
Cancer Screening
CL030490
Screening for Oral Cancer
Dispense
Dispense
C64658
CL370152
Action
Dispense
Give or apply.
owl:Class
Dispense
disp.
Activity
Instruction Imperative
AIDS Clinical Trial
Research Activity
C51359
CL353147
owl:Class
AIDS Clinical Trial
Clinical Study by Targeted Disease or Condition
AIDS Clinical Trial
A clinical trial designed to evaluate the development, safety, and efficacy of vaccines and therapeutics directed against AIDS.
AIDS Clinical Trial
AIDS Study
Liver Transplantation
Therapeutic or Preventive Procedure
Orthotopic Liver Transplant
Orthotopic Liver Transplantation
Orthotopic Liver Transplantation
Orthotopic Liver Transplantation
owl:Class
C51696
Orthotopic Liver Transplantation
CL355314
CL356378
Unbiased Estimation
Statistical Estimation
Research Activity
owl:Class
Unbiased Estimation
Unbiased Estimation
C53329
Unbiased Estimation
Relabeling
FDA
Governmental or Regulatory Activity
Relabeling
Type Of Remedial Action ICSR Terminology
Remedial Action
Individual Case Safety Report Terminology
CL357572
C53608
owl:Class
Relabeling
Relabeling
Action
owl:Class
Recovery
C70827
C1555688
Activity
Recovery
Recovery
A getting back or regaining.
Recovery
Oxymetholone Measurement
Oxymetholone Measurement
Steroid Measurement
Laboratory Procedure
Oxymetholone Measurement
The determination of the amount of oxymetholone present in a sample.
owl:Class
Oxymetholone Measurement
C75388
C0524224
A radiographic examination of the vagina using the intravaginal injection of contrast medium.
Vaginography
owl:Class
Vaginography
C0203051
C38096
Radiography
Vaginography
Vaginography
Diagnostic Procedure
owl:Class
Network Analysis
CL004057
C19374
Research Technique
Pathway Analysis
Elucidation of anabolic and catabolic pathways using labelled molecules or precursors. (NCI/OSP)
Research Activity
Pathway Analysis
Pathway Analysis
Pathway Analysis
Biopsy of Duodenum
Duodenal Biopsy
owl:Class
Removal of tissue from the duodenum for microscopic examination, using an endoscope.
CL354993
Endoscopic Biopsy of Duodenum
Procedure_Has_Partially_Excised_Anatomy only Duodenum
C51683
Biopsy of Duodenum
Biopsy of Small Intestine
Diagnostic Procedure
Biopsy of Duodenum
Biopsy of Duodenum
C64430
CL370342
Protein or Enzyme Type Measurement
Protein or Enzyme Type Measurement
owl:Class
Laboratory Procedure
Protein or Enzyme Type Measurement
Chemistry Test
Protein or Enzyme Type Measurement
C74741
CDISC SDTM Terminology
Homocysteine Acid Measurement
HOMOCY
CDISC
Clinical Data Interchange Standards Consortium Terminology
<def-source>CDISC</def-source><def-definition>A measurement of the homocysteine amino acid in a biological specimen.</def-definition>
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Code
The determination of the amount of homocysteine amino acid present in a sample.
Homocysteine Acid Measurement
CL384720
Homocysteine Acid Measurement
Homocysteine
Laboratory Procedure
Homocysteine Acid Measurement
Protein or Enzyme Type Measurement
owl:Class
The determination of the number of stacking red blood cells present in a blood sample.
owl:Class
Rouleaux Formation Count
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Terminology
ROULEAUX
Laboratory Procedure
Erythrocyte Count
<def-source>CDISC</def-source><def-definition>A measurement of the number of stacking red blood cells within a biological specimen.</def-definition>
CL384747
Rouleaux Formation Count
CDISC SEND Terminology
Clinical Data Interchange Standards Consortium Terminology
C74624
Rouleaux Formation
Rouleaux Formation Count
Rouleaux Formation Count
CDISC
CL356060
Stereotactic Biopsy
Stereotactic Biopsy of Brain
Diagnostic Procedure
Stereotactic Biopsy of Brain
Stereotactic Biopsy of Brain
C51655
An X-ray procedure using multiple coordinates to precisely determine the location of a tumor or nodule in the brain so as to obtain a tissue sample.
owl:Class
Stereotactic Biopsy of Brain
Substance Abuse, Other
C0236935
Substance Abuse, Other
C17715
Substance Abuse, Other
Substance Abuse, Other
Substance Abuse
Individual Behavior
Mental or Behavioral Dysfunction
owl:Class
Action
Return
Return
To give something back, or the getting back thereof.
owl:Class
Return
Return
C71900
Activity
CL378681
Ablative Endocrine Surgery
CL029164
C15467
Ablation Therapy
Endocrine Surgical Procedure
Destructive or removal of any part of the endocrine system by surgical means, including the use of lasers or electrical current.
Ablative Endocrine Surgery
Ablative Endocrine Surgery
Ablative Endocrine Surgery
owl:Class
Therapeutic or Preventive Procedure
Drug Formulation Process
Drug Development
Formulation
owl:Class
The act or process of developing or preparing a mixture of ingredients to create a desired end drug product, such as a specific flavor, aroma, or polymer; or the desired final drug product itself; also, a listing of the ingredients and composition of the dosage form.
Drug Formulation
Drug Formulation Process
Drug Formulation Process
Drug Formulation Process
C0524527
C15653
Occupational Activity
CL370497
C64867
owl:Class
Selective External Radiation Therapy
Selective External Radiation Therapy
Selective External Radiation Therapy
Therapeutic or Preventive Procedure
Selective External Radiation Therapy
Radiation Therapy
Malignant Neoplasm Therapy
Cancer Therapeutic Procedure
owl:Class
CL025628
Cancer Treatment
Cancer Therapeutic Procedure
Cancer Diagnostic or Therapeutic Procedure
Cancer Therapeutic Procedure
Cancer Therapeutic Procedure
C16212
Any intervention for management of a malignant neoplasm.
Therapeutic Procedure
Cancer Therapy
Malignant Neoplasm Treatment
Therapeutic or Preventive Procedure
owl:Class
Therapeutic or Preventive Procedure
Gavage
C73430
Gavage
Administration of nutritional support by means of a tube passed into the stomach.
Gastrogavage
Nutritional Support
C0041281
Gavage
Gavage
Chemoprevention
Cancer Chemoprevention
<def-source>NCI-GLOSS</def-source><def-definition>(KEE-mo-pre-VEN-shun) The use of drugs, vitamins, or other agents to try to reduce the risk of, or delay the development or recurrence of, cancer.</def-definition>
C0282515
Cancer Prevention
Therapeutic or Preventive Procedure
chemoprevention
Chemoprevention of Cancer
Chemoprevention
Chemoprevention
C15604
The use of natural or synthetic substances (e.g., drugs, vitamins, hormones, plant products) or food supplements to reduce the risk of developing a disease, to reduce the chance that disease will recur, or to delay the recurrence.
owl:Class
Chemoprevention
Concept also refers to the studies related to the identification and evaluation of agents that may be used for chemoprevention, e.g. inhibit initiation, promotion, transformation, and/or progression of the malignant process.
esophagoscopy
Gastrointestinal Endoscopy
Esophagoscopy
Diagnostic Procedure
<def-source>NCI-GLOSS</def-source><def-definition>(eh-sof-a-GAHS-ko-pee) Examination of the esophagus using a thin, lighted tube.</def-definition>
Esophagoscopy
Therapeutic or Preventive Procedure
Esophagoscopy
Esophagoscopy
owl:Class
C16560
C0014873
Procedure_Has_Target_Anatomy only Esophagus
Endoscopic examination of the esophagus.
Laboratory Procedure
C48040
Matrix Assisted Laser Desorption Ionization Mass Spectrometry
Matrix-Assisted Laser Desorption Ionization Mass Spectrometry
Matrix-Assisted Laser Desorption Ionization Mass Spectrometry
MALDI
Matrix-Assisted Laser Desorption Ionization Mass Spectrometry
A mass spectrometric technique that is used for the analysis of large biomolecules. Analyte molecules are embedded in an excess matrix of small organic molecules that show a high resonant absorption at the laser wavelength used. The matrix absorbs the laser energy, thus inducing a soft disintegration of the sample- matrix mixture into free (gas phase) matrix and analyte molecules and molecular ions. In general, only molecular ions of the analyte molecules are produced and almost no fragmentation occurs. This makes the method well suited for molecular weight determinations and mixture analysis. (CHI)
Matrix-Assisted Laser Desorption Ionization Mass Spectrometry
C0282597
owl:Class
Mass Spectrometry
Incidence Rate
C53348
Incidence Rate
Population-Based Statistic
Incidence Rate
owl:Class
Quantitative Concept
Incidence Rate
CL356677
Therapeutic Procedure
CL377710
Pre-Procedure Preparation
owl:Class
Pre-Procedure Preparation
C71314
Therapeutic or Preventive Procedure
Pre-Procedure Preparation
Pre-Procedure Preparation
Neuroscience and Neuropsychiatric Research
Biomedical Occupation or Discipline
C15964
CL003621
Investigations in the disciplines concerned with the nervous system.
Neurosciences Research
Neurosciences Research
Neurosciences Research
Neurosciences Research
owl:Class
Dental Procedure
Orthodontic Treatment
Orthodon Procedure
A dental treatment to correct malocclusions of the teeth and their surrounding structures.
owl:Class
Orthodontic Treatment
Orthodontic Treatment
C0204193
C64248
Orthodontic Treatment
Therapeutic or Preventive Procedure
owl:Class
<def-source>MSH2001</def-source><def-definition>The use of ultraviolet electromagnetic radiation in the treatment of disease, usually of the skin. This is the part of the sun's spectrum that causes sunburn and tanning. Ultraviolet A, used in PUVA, is closer to visible light and less damaging than Ultraviolet B, which is ionizing.</def-definition>
Ultraviolet Radiation Therapy
ultraviolet radiation therapy
UV Light Therapy
Light Therapy, UV
C0041626
UV Light Therapy
C15344
Phototherapy
Therapy, UV Light
<def-source>NCI-GLOSS</def-source><def-definition>A form of radiation used in the treatment of cancer.</def-definition>
Therapeutic or Preventive Procedure
UV Light Therapy
UV Light Therapy
Removal of a portion of pleural tissue, for microscopic examination.
Pleural Biopsy
Biopsy
owl:Class
C51897
Procedure_Has_Partially_Excised_Anatomy only Pleura
Pleural Biopsy
Biopsy of Pleura
C0176531
Pleural Biopsy
Pleural Biopsy
Diagnostic Procedure
CL369832
To reduce in strength or concentration, especially by the addition of water.
owl:Class
Dilute
C64657
Dilute
dil.
Activity
Dilution
Dilute
Instruction Imperative
Dilute
Prostatectomy
Nerve-Sparing Prostatectomy
Procedure_May_Have_Partially_Excised_Anatomy some 'Seminal Vesicle'
A type of surgical prostatectomy which attempts to spare the nerves that control erection.
owl:Class
CL026431
Procedure_May_Have_Partially_Excised_Anatomy some 'Vas Deferens'
Nerve-Sparing Prostatectomy
Nerve-Sparing Prostatectomy
C16218
Therapeutic or Preventive Procedure
Nerve-Sparing Surgery
Nerve-Sparing Prostatectomy
Complement Measurement
C80178
The determination of the amount of complement C4a present in a sample.
Complement C4a Measurement
owl:Class
Complement C4a Measurement
Complement C4a Measurement
Complement C4a Measurement
Laboratory Procedure
C22493
Organism Modification
Radiation-Induced Change
Techniques used for altering the genetic material of an organism by exposure to ionizing radiation.
owl:Class
Research Activity
Radiation-Induced Change
Radiation
Radiation-Induced Change
Radiation-Induced Change
Radiation
CL100931
Any representation of the individual steps in a metabolic pathway of a cell.
Modeling of Cellular Pathways
Modeling of Cellular Pathways
CL015638
Modeling of Cellular Pathways
owl:Class
C20067
Modeling of Cellular Pathways
Activity
Computer Modeling
Acustimulation Therapy
CL032876
Acustimulation
owl:Class
acustimulation
C15761
Acustimulation Therapy
Acupuncture Therapy
Acustimulation Therapy
<def-source>NCI-GLOSS</def-source><def-definition>Mild electrical stimulation of acupuncture points to control symptoms such as nausea and vomiting.</def-definition>
Acustimulation Therapy
Therapeutic or Preventive Procedure
Use of a low intensity electrical current to provide mild stimulation of the body's acupuncture points in order to control symptoms such as nausea and vomiting.
C15429
Research Activity
owl:Class
Systematic investigation into a subject in order to discover facts, establish or revise a theory, or develop a plan of action based on the facts discovered.
Clinical or Research Activity
Research Activity
Research
Research Activity
C0242481
Research Activity
Research Activity
Screening Mammography
Diagnostic Procedure
C79417
Screening Method
Screening Mammography
Mammography
Screening Mammography
owl:Class
Screening Mammography
C1509144
Action
Pooling
Activity
Pool
owl:Class
Pool
Pool
Pool
Combine together into a single unit, group, or sample.
Pooled
C68779
owl:Class
CL384385
Crystal Growth Measurement
The determination of the amount of crystals present in a sample.
Chemistry Test
C74948
Crystal Growth Measurement
Crystal Growth Measurement
Crystal Growth Measurement
Laboratory Procedure
The determination of the amount of interleukin 15 present in a sample.
C74811
Interleukin 15 Measurement
CDISC SDTM Terminology
Interleukin 15 Measurement
CL384292
INTLK15
Clinical Data Interchange Standards Consortium Terminology
Cytokine Measurement
Interleukin 15 Measurement
<def-definition>A measurement of the interleukin 15 in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Laboratory Test Terminology by Code
owl:Class
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Name
Interleukin 15
Interleukin 15 Measurement
CDISC SEND Terminology
Action
Reposition
Repositioned
CL384225
Activity
Reposition
owl:Class
Repositioning
The act of placing in a new position.
Reposition
C73790
Reposition
Surveillance Modeling
Surveillance Modeling
C15935
Surveillance Modeling
Modeling
Surveillance Modeling
Research Activity
owl:Class
CL003234
Nephrectomy
C0027695
nephrectomy
Urologic Surgical Procedure
C15284
Nephrectomy
Procedure_Has_Excised_Anatomy only Kidney
<def-source>NCI-GLOSS</def-source><def-definition>(nef-REK-toe-mee) Surgery to remove a kidney. Radical nephrectomy removes the kidney, the adrenal gland, nearby lymph nodes, and other surrounding tissue. Simple nephrectomy removes only the kidney. Partial nephrectomy removes the tumor but not the entire kidney.</def-definition>
owl:Class
<def-source>MSH2001</def-source><def-definition>Excision of a kidney. (Dorland, 28th ed)</def-definition>
Nephrectomy
Therapeutic or Preventive Procedure
Nephrectomy
CL014345
Prior Therapy
Prior Adjuvant Other Therapy
Clinical Attribute
C16158
owl:Class
Prior Adjuvant Other Therapy
Prior Adjuvant Other Therapy
Prior Adjuvant Other Therapy
CDISC
owl:Class
CDISC SDTM Terminology
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Name
Iron Binding Capacity
Unsaturated Iron Binding Capacity Measurement
IBCU
Unsaturated Iron Binding Capacity
Unsaturated Iron Binding Capacity Measurement
Unsaturated Iron Binding Capacity Measurement
Clinical Data Interchange Standards Consortium Terminology
CDISC SEND Terminology
C74719
Unsaturated Iron Binding Capacity Measurement
C0202106
The determination of the binding capacity of unsaturated iron in a sample.
<def-source>CDISC</def-source><def-definition>A measurement of the binding capacity of unsaturated iron in a biological specimen.</def-definition>
CDISC SDTM Laboratory Test Terminology by Code
The observable response of a person.
C19683
Personal Behavior
Behavior
Individual Behavior
CL008501
Personal Conduct
Personal Behavior
Personal Behavior
owl:Class
Personal Behavior
Lysergide Measurement
The determination of the amount of lysergide (LSD) present in a sample.
owl:Class
Lysergic Acid Diethylamide Measurement
Lysergide Measurement
C0202406
Laboratory Procedure
Lysergide Measurement
LSD Measurement
Hallucinogen Measurement
C75354
Lysergide Measurement
Gingivectomy
Gingivectomy
C82090
owl:Class
Gingivectomy
A resective periodontal surgical procedure that removes gingival tissue.
Gingivectomy
Periodontal Treatment
Health Care Activity
Diagnostic Reagents and Test Kits
owl:Class
Conceptual Entity
Diagnostics, Cancer
Diagnostics, Cancer
C15799
Diagnostics, Cancer
CL000307
Diagnostics, Cancer
Reagents and techniques used for the diagnosis of cancer.
Crystallography
C16476
C0010424
Research Technique
Crystallography
Crystallography
Crystallography
Laboratory Procedure
owl:Class
Action
CL333215
Review
owl:Class
Review
The act of appraisal, evaluation, or analysis.
Review
Activity
C42729
Review
EGD
Esophagogastroduodenoscopy
C0079304
Esophagogastroduodenoscopy
C78144
Esophagogastroduodenoscopy
Health Care Activity
Procedure_Has_Target_Anatomy some Esophagus
owl:Class
Procedure_Has_Target_Anatomy some Stomach
Esophagogastroduodenoscopy
Diagnostic Procedure
An endoscopic procedure that visualizes the upper part of the gastrointestinal tract up to the duodenum.
Gastrointestinal Endoscopy
Procedure_Has_Target_Anatomy some Duodenum
C68790
Exenteration
Removal of internal organs and tissues, usually radical removal of the contents of a body cavity.
Therapeutic or Preventive Procedure
C0015258
Exenteration
Evisceration
owl:Class
Excision
Exenteration
Exenteration
Cardiovascular Surgical Procedure
Therapeutic or Preventive Procedure
Surgical Procedure by Site or System
Cardiovascular Surgical Procedure
owl:Class
Procedure_Has_Target_Anatomy some 'Cardiovascular System'
C49803
CL355008
Cardiovascular Surgical Procedure
Cardiovascular Surgical Procedure
Management of Therapy Complications
Therapeutic or Preventive Procedure
CL033463
C15476
Management of Therapy Complications
Supportive Care
Management of Therapy Complications
Management of Therapy Complications
owl:Class
CDISC SDTM Laboratory Test Terminology by Code
CD19
Lymphocyte Count
C74606
CDISC SEND Terminology
CDISC
Clinical Data Interchange Standards Consortium Terminology
CD19 Expressing B Cell Count
CL384374
owl:Class
The determination of the number of CD19 expressing B cells present in a sample.
CD19 Expressing B Cell Count
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Name
CD19 Expressing B Cell Count
Laboratory Procedure
CD19 Expressing B Cell Count
<def-source>CDISC</def-source><def-definition>A count of the CD19 B cells per unit of a biological specimen.</def-definition>
Sentinel Lymph Node Biopsy with Axillary Lymph Node Dissection
Sentinel Lymph Node Biopsy with Axillary Lymph Node Dissection
CL343344
Diagnostic Lymphadenectomy
Axillary Lymph Node Dissection
owl:Class
Diagnostic Procedure
Sentinel Lymph Node Biopsy with Axillary Lymph Node Dissection
C47854
Sentinel Lymph Node Biopsy with Axillary Lymph Node Dissection
A surgical procedure in which the sentinel node is removed followed by dissection and removal of the axillary node group.
One Sample t-Test
CL356336
C53240
owl:Class
One Sample t-Test
Quantitative Concept
One Sample t-Test
One Sample t-Test
t-Test
C16010
owl:Class
Research Activity
Scientist Exchange Program
Scientist Exchange Program
CL004329
Occupational Activity
Office of International Activities sponsors two international scientist exchange programs: Short-Term Scientist Exchange Program and Oncology Research Faculty Development Program
Scientist Exchange Program
Scientist Exchange Program
HercepTest
HercepTest
Diagnostic Procedure
HercepTest
C25524
owl:Class
Histologic Test
Laboratory Procedure
CL052235
An FDA approved test for the evaluation of HER2 protein overexpression in breast tumors. It provides semi-quantitative results of p185HER2 (HER2 gene) overexpression in Bouin or formalin-fixed, routinely processed, paraffin-embedded breast cancer tissues by light microscopy.
HercepTest
Boyd BSA Formula
owl:Class
Boyd Body Surface Area Formula
Occupational Activity
Boyd Body Surface Area Formula
Boyd Body Surface Area Formula
Boyd
Boyd Body Surface Area Formula
C68650
CL374288
The formula to calculate body surface area as described by E Boyd. It is mathematically defined as: BSA (m^2) = 0.0003207 x [Height(cm)^0.3] x [Weight(g)^(0.7285 - ( 0.0188 x LOG(g))]
Body Surface Area Formula
Biopsy of Breast
Biopsy of Breast
C51698
Removal of tissue from the breast for microscopic examination.
Diagnostic Procedure
CL354438
Biopsy
Breast Biopsy
Biopsy of Breast
Procedure_Has_Partially_Excised_Anatomy only Breast
Biopsy of Breast
owl:Class
Clinical Trials: Cancer Control
Clinical Trials: Cancer Control
Trial Indication Type
owl:Class
Clinical Study by Targeted Disease or Condition
CL008685
Research Activity
Clinical Trials: Cancer Control
C16095
Clinical Trials: Cancer Control
Bioassay, in vivo
A laboratory test or analysis of the biological properties or activities of a substance performed by testing its effect on an organism.
Bioassay, in vivo
Bioassay, in vivo
in vivo test
owl:Class
Bioassay, in vivo
Laboratory Procedure
C18641
CL000092
in vivo Bioassay
Bioassay
Procedure_Has_Target_Anatomy only 'Anterior Mediastinum'
Chamberlain procedure
Anterior Mediastinotomy
Anterior Mediastinotomy
Therapeutic or Preventive Procedure
Anterior Mediastinotomy
anterior mediastinotomy
Mediastinotomy
C0442952
Anterior Mediastinotomy
<def-source>NCI-GLOSS</def-source><def-definition>(MEE-dee-a-stin-AH-toe-mee) A procedure in which a tube is inserted into the chest to view the tissues and organs in the area between the lungs and between the breastbone and heart. The tube is inserted through an incision next to the breastbone. This procedure is usually used to get a tissue sample from the lymph nodes on the left side of the chest.</def-definition>
C15647
owl:Class
Surgical opening of the anterior mediastinum.
Laboratory Procedure
LC
Liquid Chromatography
C16435
Chromatography
Liquid Chromatography
A type of chromatography in which separation of a mixture is achieved by passing a sample in a stream of liquid solvent through some form of material that will provide resistance by virtue of chemical interactions between the components of the sample and the material.
<def-source>MSH2001</def-source><def-definition>Chromatographic techniques in which the mobile phase is a liquid.</def-definition>
Liquid Chromatography
owl:Class
Liquid Chromatography
C0008565
Amplification
This technique refers to selectively replicate DNA sequence of interest to multiple extra copies that meet the need of research or health care activity. Polymerase chain reaction (PCR), can be considered a type of man-made gene amplification process.
Gene Amplification Technique
Gene Amplification Technique
owl:Class
C20589
Molecular Genetic Technique
Gene Amplification Technique
C1517480
Gene Amplification Technique
Molecular Biology Research Technique
Correlation Test
Statistical Test
Correlation Test
Quantitative Concept
Correlation Test
C53236
Correlation Test
CL356426
owl:Class
Research Activity
Part of the National Surgical Adjuvant Breast and Bowel Project, the Breast Cancer Prevention Trial (BCPT) was a clinical trial designed to see whether taking the drug tamoxifen would prevent breast cancer in women who are at an increased risk of developing the disease. The BCPT also looked at whether taking tamoxifen would decrease the number of heart attacks and reduce the number of bone fractures in these women. The study began recruiting participants in April 1992 and closed enrollment in September 1997.
BCPT
Breast Cancer Prevention Trial
Breast Cancer Prevention Trial
CL008220
Breast Cancer Prevention Trial
Breast Cancer Prevention Trial
owl:Class
C16069
Cancer Prevention Trial
CL014341
Prior Adjuvant HDC/ASCT
Prior Adjuvant HDC/ASCT
Clinical Attribute
Prior Adjuvant HDC/ASCT
owl:Class
Prior Adjuvant High-Dose Chemotherapy with Stem Cell Support
Prior Adjuvant HDC/ASCT
C16155
Prior Chemotherapy
Behavioral Research
owl:Class
Research Activity
The assessment of basic principles of behavior, including both basic laboratory research and research directed at individuals.
Basic Biobehavioral Research
CL003982
Basic Biobehavioral Research
C15994
Basic Biobehavioral Research
Basic Biobehavioral Research
Radiography
owl:Class
Chest X-ray
Chest Radiography
Diagnostic Procedure
Chest Radiography
Chest Radiography
An x-ray examination of the chest.
C0039985
C38103
Chest Radiography
The measurement of radiation by photography, as in x-ray film and film badge, by Geiger-Mueller tube, and by scintillation counting.
Radiometry (Microwave)
C15980
Radiometry (Microwave)
Health Care Activity
Radiometry (Microwave)
CL003825
Radiation Dosimetry
Research Activity
Radiometry (Microwave)
owl:Class
C82392
owl:Class
Fluid Attenuated Inversion Recovery
Magnetic Resonance Imaging
FLAIR
A magnetic resonance imaging (MRI) pulse sequence that uses an inversion recovery technique to null fluids present in the imaging area, improving clarity of the object of interest.
Fluid Attenuated Inversion Recovery
Fluid Attenuated Inversion Recovery
Diagnostic Procedure
Fluid Attenuated Inversion Recovery
Cell Fusion
Cell Biology, Cell Fusion
Research Activity
Cell Fusion
Cell Fusion
Basic Science Research
owl:Class
C0007594
A technique to form a single hybrid cell, by fusion of two or more dissimilar cells, either spontaneously or by induced fusion. The cells fuse and coalesce, but their nuclei may remain separated. The cell fusion technique can be used as a method of assigning genes to specific chromosomes.
C16401
Cell Fusion
CL343647
CAM Multimodality Therapy
Gerson Therapy
Gerson Diet
owl:Class
C62680
Gerson Therapy
Therapeutic or Preventive Procedure
Gerson Therapy
Gerson Therapy
IMPORT
Imported
Import
Import
Activity
FDA
Importation
CL383726
Structured Product Labeling Business Operation Terminology
C73599
Import
An activity concerned with bringing any good, commodity, or service from a foreign source.
Import
owl:Class
Action
Plan
Activity
owl:Class
Plan
C1301732
Plan
Action
C25619
Planning
To devise, contrive, or formed in design.
Planned
Plan
C64547
CDISC SDTM Terminology
Protein or Enzyme Type Measurement
Creatinine Measurement
CDISC
CDISC SDTM Laboratory Test Terminology by Name
Creatinine Measurement
Creatinine
CREAT
C0201975
CDISC SEND Terminology
A quantitative measurement of the amount of creatinine present in a sample.
CDISC SDTM Laboratory Test Terminology by Code
Creatinine Measurement
Laboratory Procedure
<def-source>CDISC</def-source><def-definition>A measurement of the creatinine in a biological specimen.</def-definition>
Creatinine Measurement
owl:Class
Clinical Data Interchange Standards Consortium Terminology
Incisional Biopsy
Open Biopsy
Incisional Biopsy
<def-source>NCI-GLOSS</def-source><def-definition>(in-SI-zhun-al BY-op-see) A surgical procedure in which a portion of a lump or suspicious area is removed for diagnosis. The tissue is then examined under a microscope.</def-definition>
Incisional Biopsy
Biopsy
C15386
C0184922
A surgical procedure in which part of a lesion is removed for microscopic examination.
Diagnostic Procedure
owl:Class
incisional biopsy
Incisional Biopsy
Therapeutic or Preventive Procedure
owl:Class
Cancer Immunotherapy
Macrophage Colony-Stimulating Factor/Monoclonal Antibody R24
Macrophage Colony-Stimulating Factor/Monoclonal Antibody R24
CL030397
M-CSF/MOAB R24
Macrophage Colony-Stimulating Factor/Monoclonal Antibody R24
Macrophage Colony-Stimulating Factor/Monoclonal Antibody R24
C15537
Lung Biopsy
Procedure_Has_Partially_Excised_Anatomy only Lung
Removal of tissue from the lung, for microscopic examination.
Biopsy of Lung
CL355228
owl:Class
Lung Biopsy
C51748
Biopsy
Lung Biopsy
Lung Biopsy
Diagnostic Procedure
The utilization of small (&lt;100 nm), stable particles in a variety of technologies. Based on an understanding of chemical, biological and physical phenomena at the nanoscale level, processes are employed to create new nanoparticle technologies.
Non Clinical Nanoparticle Application
Activity
owl:Class
Non-Clinical Nanoparticle Application
CL364949
Non-Clinical Nanoparticle Application
Nanoparticle Application
C62313
Non-Clinical Nanoparticle Application
Non-Clinical Nanoparticle Application
Serum Sodium Measurement
Sodium Measurement
owl:Class
Serum Chemistry Measurement
A quantitative measurement of the amount of sodium present in a sample of serum.
Laboratory Procedure
C0523891
Serum Sodium Measurement
Serum Sodium Measurement
Serum Sodium Measurement
C61029
Amphetamine Drug Class Measurement
C74687
Clinical Data Interchange Standards Consortium Terminology
Amphetamine Drug Class Measurement
CL361081
CDISC SDTM Laboratory Test Terminology by Name
Amphetamine Drug Class Measurement
Laboratory Procedure
<def-source>CDISC</def-source><def-definition>A measurement of any amphetamine class drug present in a biological specimen.</def-definition>
AMPHET
CNS Stimulant Drug Measurement
CDISC SDTM Laboratory Test Terminology by Code
Amphetamine Drug Class Measurement
owl:Class
CDISC SEND Terminology
The determination of the amount of amphetamine present in a sample.
CDISC SDTM Terminology
Amphetamine
CDISC
Bootstrapping
Bootstrapping
CL387460
Statistical Technique
C78547
owl:Class
A method for estimating properties of a dataset by measuring those properties when sampling from an approximating distribution.
Bootstrapping
Quantitative Concept
Bootstrapping
C65017
C1258068
owl:Class
Nutritional Therapy
Nutritional Therapy
Nutritional Therapy
Therapeutic Procedure
Therapeutic or Preventive Procedure
Nutritional Therapy
Nutritional Intervention
Laboratory Procedure
Real Time PCR
C51962
Real Time Polymerase Chain Reaction
CL355432
Real Time PCR
Real Time PCR
owl:Class
Polymerase Chain Reaction
Molecular Biology Research Technique
Real Time PCR
Pain Management Method
Electroanalgesia
Electroanalgesia
Application of electrical stimulation to the spinal cord, deep brain, peripheral nerves, and Chinese acupoints in an effort to relieve pain. It is often used in place of or to augment the effectiveness of analgesics. There are many different types of electroanalgesia with varying levels of effectiveness and invasiveness. (White, Li, and Chiu)
owl:Class
Electroanalgesia
C21012
Therapeutic or Preventive Procedure
Neuroaugmentation Techniques
Electroanalgesia
CL055374
Action
Treatment
Administration
C25409
Activity
owl:Class
Administration
CL336466
Administration
The act of the dispensing, applying, or tendering of something to another, such as administration of a medicine.
Administration
Research Activity
Research Activity
Biomaterials Research
Biomaterials Research
C16122
CL012614
owl:Class
Research concerned with the application of biomaterials and the development of novel biomaterials.
Biomaterials Research
Biomaterials Research
Left Salpingectomy
CL354070
Salpingectomy
Left Salpingectomy
Therapeutic or Preventive Procedure
Left Salpingectomy
Left Salpingectomy
Surgery to remove part or all of the left fallopian tube.
owl:Class
Procedure_Has_Excised_Anatomy only 'Left Fallopian Tube'
C51607
Molecular Analysis
owl:Class
Analysis of protein components in a sample. The most basic analysis involves determination of the mass or concentration of protein by any of a number of quantitative assays. Increased level of detail in the analysis requires resolution of a mixture into its component proteins. The characterization of a pure protein includes the determination of a number of its properties, among these, the molecular weight, isoelectric point, subunit composition, tryptic map, amino acid composition, amino acid sequence, hydrodynamics (s value, frictional coefficient, shape, aggregation state), thermodynamics (melting, folding, protein-protein interactions), and atomic structure (NMR, diffraction).
Protein Analysis
C18962
Protein Analysis
Laboratory Procedure
CL000766
Protein Analysis
Protein Analysis
NO ASSESSMENT
No Assesment
Intellectual Product
C82477
owl:Class
Regulatory Assessment
No Assesment
No Assesment
No Assesment
C63341
CL365229
Anticoagulation Therapy
Anticoagulation Treatment
Supportive Care
Anticoagulation Therapy
owl:Class
Drug treatment to thin the blood in order to prevent or reduce blood clot formation.
Therapeutic or Preventive Procedure
Anticoagulation Therapy
Anticoagulation Therapy
Polyoma Virus Middle T
Polyoma Virus Middle T Staining Method
Polyoma Virus Middle T Staining Method
CL336295
C23034
Polyoma Virus Middle T Staining Method
PYMT
Polyoma Virus Middle T Staining Method
owl:Class
Special Histology Staining Method
Polyoma Virus Middle T Staining Method
Laboratory Procedure
Polyoma virus encodes three proteins, the large T (PyLT), middle T (PymT), and small T (Pyst) antigens, that bind p53 and thus block the function of p53. This immunohistochemical technique is used to identify metastasis-related genes using antibodies directed at Polyoma Virus Middle T antigen.
Ferritin Measurement
CDISC SEND Terminology
Protein or Enzyme Type Measurement
Laboratory Procedure
FERRITIN
Ferritin Measurement
C74737
<def-source>CDISC</def-source><def-definition>A measurement of the ferritin in a biological specimen.</def-definition>
CDISC SDTM Terminology
The determination of the amount of ferritin present in a sample.
Ferritin Measurement
Ferritin Measurement
C0373607
Ferritin
CDISC SDTM Laboratory Test Terminology by Name
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Code
CDISC
owl:Class
CL031783
Cytokine Therapy
Keratinocyte Growth Factor Therapy
C15673
Therapeutic or Preventive Procedure
Keratinocyte Growth Factor Therapy
owl:Class
Keratinocyte Growth Factor Therapy
Keratinocyte Growth Factor Therapy
Molecular Genetic Technique
Immortalized
Immortalization
C82424
owl:Class
Immortalization
Laboratory methods used to generate cells that are able to reproduce indefinitely.
Molecular Biology Research Technique
Immortalization
Immortalization
Internal Radiation Therapy
Radiation Therapy
CL054336
owl:Class
Internal Radiation Therapy
Internal Radiation
Therapeutic or Preventive Procedure
Internal Radiation Therapy
C28022
internal radiation
<def-source>NCI-GLOSS</def-source><def-definition>(ray-dee-AY-shun) A procedure in which radioactive material sealed in needles, seeds, wires, or catheters is placed directly into or near a tumor. Also called brachytherapy, implant radiation, or interstitial radiation therapy.</def-definition>
Internal Radiation Therapy
Reexcision
Re-Excision
C48600
Re-Excision
A surgical procedure to remove the remaining abnormal tissues from the body, not completely removed in an earlier attempt.
owl:Class
Re-Excision
Excision
Therapeutic or Preventive Procedure
Re-Excision
CL343028
Transanal Excision
Procedure_Has_Excised_Anatomy only Colon
Transanal Disc Excision
CL365104
Transanal Excision
Therapeutic or Preventive Procedure
C62398
Transanal Disk Excision
owl:Class
Transanal Excision
Digestive System Surgery
Transanal Excision
Surgery for rectal cancer that spares the anus and leaves the sphincter intact. Surgery is performed through the anus and removes only the rectal tumor and small amounts of surrounding tissue.
Genetic Testing for Cancer Risk
Laboratory Procedure
Genetic Testing for Cancer Risk
owl:Class
C15638
Genetic Testing
C0393006
Genetic Testing for Cancer Risk
Analyzing DNA to look for a genetic alteration that may indicate an increased risk for developing a cancer.
Diagnostic Procedure
Genetic Testing for Cancer Risk
electroacupuncture
<def-source>NCI-GLOSS</def-source><def-definition>A procedure in which pulses of weak electrical current are sent through acupuncture needles into acupuncture points in the skin. This procedure is being studied in the prevention of nausea and vomiting in patients undergoing chemotherapy.</def-definition>
Electroacupuncture Therapy
owl:Class
Acupuncture Therapy
Electroacupuncture Therapy
C0013794
Electroacupuncture
C28146
Electroacupuncture Therapy
Electroacupuncture Therapy
Therapeutic or Preventive Procedure
<def-source>MSH2002_06_01</def-source><def-definition>A form of acupuncture using low frequency electrically stimulated needles to produce analgesia and anesthesia and to treat disease.</def-definition>
owl:Class
Protein or Enzyme Type Measurement
Apolipoprotein AII Measurement
C82000
Apolipoprotein AII Measurement
Apolipoprotein AII Measurement
Apolipoprotein AII Measurement
The determination of the amount of apolipoprotein AII present in a sample.
Mutual Information Value
Mutual Information Value
C63898
Statistical Technique
Mutual Information Score
Expresses the extent to which the observed frequency of co-occurrence differs from that expected under the null hypothesis.
owl:Class
Mutual Information Value
CL366404
Mutual Information Value
Quantitative Concept
C15742
Post Remission Therapy
postremission therapy
Postremission Therapy
Postremission Therapy
CL032275
Chemotherapy
Therapeutic or Preventive Procedure
owl:Class
Postremission Therapy
Postremission Therapy
<def-source>NCI-GLOSS</def-source><def-definition>Anticancer drugs given to kill cancer cells that survive after remission induction therapy.</def-definition>
Excision of Soft Tissue
Excision of Soft Tissue
CL353350
owl:Class
C51757
Excision
Excision of Soft Tissue
Therapeutic or Preventive Procedure
Excision of Soft Tissue
Staining Method
Staining Method
Laboratory Procedure
Any of the various methods that use a dye, reagent, or other material for producing coloration in tissues or microorganisms for microscopic examination.
C0487602
Staining Method
owl:Class
C23010
Staining Methods
Histological Procedure
Staining
Staining Method
Staining Methods
monitoring
owl:Class
Clinical Trials Design
Clinical Trials, Monitoring
Clinical Data Interchange Standards Consortium Terminology
<def-source>CDISC</def-source><def-definition>The act of overseeing the progress of a clinical trial, and of ensuring that it is conducted, recorded, and reported in accordance with the protocol, standard operating procedures (SOPs), good clinical practice (GCP), and the applicable regulatory requirement(s). [ICH E6 Glossary]</def-definition>
Clinical Trials, Monitoring
CL000231
CDISC
Clinical Trials, Monitoring
Governmental or Regulatory Activity
For clinical decision-making, the purposeful and ongoing acquisition, interpretation, and synthesis of patient data obtained from clinical trials.
Clinical Trials, Monitoring
C15789
Clinical Data Interchange Standards Consortium Glossary Terminology
C0039989
Procedure_Has_Target_Anatomy only 'Thoracic Cavity'
Therapeutic or Preventive Procedure
thoracoscopy
Thoracoscopy
Endoscopic Procedure
Diagnostic Procedure
Thoracoscopy
owl:Class
C17196
Thoracoscopy
Thoracoscopy
<def-source>NCI-GLOSS</def-source><def-definition>The use of a thin, lighted tube (called an endoscope) to examine the inside of the chest.</def-definition>
Endoscopic examination of the thoracic cavity.
Thyrotropin Releasing Hormone
The determination of the amount of thyrotropin releasing hormone present in a sample.
C74874
Laboratory Procedure
CDISC SDTM Terminology
Thyrotropin Releasing Factor
Thyrotropin Releasing Hormone Measurement
CDISC SDTM Laboratory Test Terminology by Name
Thyrotropin Releasing Hormone Measurement
CDISC SDTM Laboratory Test Terminology by Code
CL384354
Thyrotropin Releasing Hormone Measurement
Thyrotropin Releasing Hormone Measurement
Hormone Measurement
CDISC SEND Terminology
owl:Class
TRH
Clinical Data Interchange Standards Consortium Terminology
<def-definition>A measurement of the thyrotropin releasing hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
Statistical Modeling
owl:Class
CL386503
Hidden Markov Model
Research Activity
C75940
Hidden Markov Model
HMM
Hidden Markov Model
A statistical model in which the system being modeled has unknown parameters, but the hidden parameters can be determined from the observable parameters. While the state is not directly visible, the variables influenced by the state are visible. Each state has a probability distribution over the possible output tokens. Therefore the sequence of tokens generated by a Hidden Markov Model (HMM) gives some information about the sequence of states.
Hidden Markov Model
Isotope Therapy
Isotope Therapy
Isotope Therapy
Therapeutic or Preventive Procedure
therapy, isotope, radioactive
Radioactive Isotope Therapy
C15470
owl:Class
Radiation Therapy
CL029167
Isotope Therapy
Therapeutic Use Study
owl:Class
Therapeutic Use Study
C39539
Therapeutic Use Study
Therapeutic Use Study
Therapeutic Clinical Trial
The Therapeutic Use Study is a clinical study that is conducted with the purpose to refine understanding of therapy risk-benefit relationship in general or special populations and/or environments; to identify less common adverse reactions, and to refine dosing/regimen/indications recommendations.
CL323634
Research Activity
Surgical Procedure by Site or System
C0024881
Mastectomy
mastectomy
Mastectomy
Mastectomy
Mammectomy
Surgical removal of the breast.
C15277
owl:Class
Procedure_Has_Excised_Anatomy only 'Mammary Gland'
Mastectomy
Therapeutic or Preventive Procedure
Breast Cancer Therapeutic Procedure
<def-source>NCI-GLOSS</def-source><def-definition>(mas-TEK-toe-mee) Surgery to remove the breast (or as much of the breast tissue as possible).</def-definition>
Procedure_Has_Excised_Anatomy only Breast
Replication Initiation Point Mapping
owl:Class
Gene Mapping
RIP Mapping
Replication Initiation Point Mapping
Laboratory Procedure
Molecular Biology Research Technique
Replication Initiation Point Mapping
Replication Initiation Point Mapping
Replication initiation point (RIP) mapping detects start sites for DNA synthesis at the nucleotide level and thus monitors replication initiation events at the origin very precisely. Beyond detecting the precise positions of start sites, the application of RIP mapping in yeast and human cells has revealed a single, defined start point at which replication initiates. (J Cell Sci 2001 Feb;114(Pt 4):643-51)
CL026368
C20320
Fatty Acid Binding Protein 1 Measurement
The determination of the amount of fatty acid binding protein-1 present in a sample.
C82012
Fatty Acid Binding Protein 1 Measurement
Protein or Enzyme Type Measurement
Fatty Acid Binding Protein 1 Measurement
Fatty Acid Binding Protein 1 Measurement
owl:Class
Activity
Tau
CL371503
Tau
Tau
Tau
The difference, alpha2 minus alpha1.
C67052
Statistical Technique
owl:Class
Lab Lupus Inhibitor Test
Assay
Laboratory Procedure
CL375817
Laboratory test to determine whether a lupus anticoagulant is present in the subject. Presence of a lupus inhibitor is most often detected by prolongation of the activated partial thromboplastin time. Presence of a lupus anticoagulant may actually increase risk for blood clots, and may indicate presence of systemic lupus. See definition of lupus anticoagulant for more details.
Lab Lupus Inhibitor Test
owl:Class
Lab Lupus Inhibitor Test
C70648
Lab Lupus Inhibitor
Lab Lupus Inhibitor Test
CDISC SEND Terminology
Epithelial Cells
EPIC
<def-source>CDISC</def-source><def-definition>A measurement of the epithelial cells in a biological specimen.</def-definition>
Clinical Data Interchange Standards Consortium Terminology
The determination of the number of epithelial cells in a sample.
CDISC SDTM Laboratory Test Terminology by Code
CDISC
Epithelial Cell Count
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Name
Epithelial Cell Count
Epithelial Cell Count
owl:Class
Epithelial Cell Count
CDISC SDTM Terminology
C64605
Cell Count
C1273342
CL008195
Black/White Cancer Survival Study
BWCSS
Cancer Surveillance Project
A study designed to investigate the significance of social, behavioral, lifestyle, biological, treatment, and health care factors in relation to the observed differences in cancer survival between African-Americans and white Americans. Data was collected on more than 3,400 patients, focusing on cancers of the breast, colon, uterus, and bladder.
Black/White Cancer Study
Research Activity
owl:Class
Black/White Cancer Survival Study
Black/White Cancer Survival Study
C16067
Black/White Cancer Survival Study
<def-source>CDISC</def-source><def-definition>A natural or surgically-induced connection between tubular structures in the body. (NCI)</def-definition>
Anastomosis
CDISC SDTM Anatomical Location Terminology
Anastomosis
Anastomosis
Anastomotic
C0677554
A natural or surgically-induced connection between tubular structures in the body.
<def-source>NCI-GLOSS</def-source><def-definition>(an-AS-ta-MO-sis) A procedure to connect healthy sections of tubular structures in the body after the diseased portion has been surgically removed.</def-definition>
Clinical Data Interchange Standards Consortium Terminology
CDISC
anastomosis
CDISC SDTM Terminology
Surgical Procedure by Method
Therapeutic or Preventive Procedure
Anastomosis
C15609
ANASTOMOSIS
owl:Class
Therapeutic or Preventive Procedure
C51991
Whole-Abdominal Irradiation
Whole-Abdominal Irradiation
owl:Class
Extensive Radiation
CL356160
Whole-Abdominal Irradiation
Whole-Abdominal Irradiation
Vitamin Measurement
Laboratory Procedure
C74803
Vitamin Measurement
The determination of the type and amount of vitamins in a sample.
Vitamin Measurement
Chemistry Test
Vitamin Measurement
owl:Class
C0428580
owl:Class
A medical inspection, qualified according to the methods employed, as physical examination, radiologic examination, diagnostic imaging examination, etc., performed under conditions of patient's complete or partial local or general insensibility to pain with or without the loss of consciousness, induced by an anesthetic agent or by non-pharmacological anesthesia technique.
Examination Under Anesthesia
C0558588
Examination Under Anesthesia
C40971
Examination Under Anesthesia
Diagnostic Procedure
Medical Examination
Examination Under Anesthesia
Urothelial Toxicity Attenuation
Therapeutic or Preventive Procedure
Toxicity Attenuation
Urothelial Toxicity Attenuation
C15535
Urothelial Toxicity Attenuation
Urothelial Toxicity Attenuation
owl:Class
CL030375
C15572
Prevention of Prostate Cancer
owl:Class
Cancer Prevention
CL030677
Prevention of Prostate Cancer
Prostate Cancer Prevention
Therapeutic or Preventive Procedure
Prevention of Prostate Cancer
Prevention of Prostate Cancer
Argon Plasma Coagulation
owl:Class
C66714
CL371046
Therapeutic or Preventive Procedure
Therapeutic Surgical Procedure
Argon Plasma Coagulation
Argon Plasma Coagulation
Argon Plasma Coagulation
A non-contact form of electrocoagulation in which high-frequency electric current is delivered via ionized argon gas to cause coagulation and destruction of tissue.
Non-esterified Fatty Acids Measurement
Non-esterified Fatty Acids Measurement
The determination of the amount of non-esterified fatty acids present in a sample.
Laboratory Procedure
Fatty Acid Measurement
Non-esterified Fatty Acids Measurement
Non-esterified Fatty Acids Measurement
C80200
owl:Class
C0373675
Magnesium Measurement
CDISC
<def-source>CDISC</def-source><def-definition>A measurement of the magnesium in a biological specimen.</def-definition>
Magnesium
owl:Class
C64840
Magnesium Measurement
Laboratory Procedure
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Terminology
A quantitative measurement of the amount of magnesium present in a sample.
Magnesium Measurement
Electrolyte Measurement
CDISC SDTM Laboratory Test Terminology by Code
MG
Magnesium Measurement
Clinical Data Interchange Standards Consortium Terminology
Role of Vitamin E (alpha-tocopherol), its precursons, and its analogs in cancer causation or prevention and in general health.
CL102258
Nutrition, Vitamins
Nutrition, Vitamin E
Nutrition, Vitamin E
Nutrition, Vitamin E
C15929
owl:Class
Nutrition, Vitamin E
Research Activity
C0005771
Blood Cell Count
Blood Cell Count
CBC
<def-source>NCI-GLOSS</def-source><def-definition>A test to check the number of red blood cells, white blood cells, and platelets in a sample of blood. Also called complete blood count (CBC).</def-definition>
FBC
blood cell count
The determination of the number of red blood cells, white blood cells, and platelets in a blood sample.
Cell Count
C28133
Laboratory Procedure
owl:Class
Complete Blood Count
Hematology Test
Full Blood Count
Blood Cell Count
Blood Cell Count
Clinical Attribute
Prior Hormone Therapy
owl:Class
Prior Adjuvant Hormonal Therapy
Prior Adjuvant Hormonal Therapy
CL014343
Prior Adjuvant Hormonal Therapy
Prior Adjuvant Hormonal Therapy
C16156
C74817
Interleukin 20 Measurement
<def-definition>A measurement of the interleukin 20 in a biological specimen.</def-definition><def-source>CDISC</def-source>
The determination of the amount of interleukin 20 present in a sample.
Interleukin 20 Measurement
CDISC SDTM Laboratory Test Terminology by Code
owl:Class
CDISC SDTM Terminology
CL384298
Cytokine Measurement
Interleukin 20 Measurement
Interleukin 20
Clinical Data Interchange Standards Consortium Terminology
INTLK20
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
Interleukin 20 Measurement
CDISC SEND Terminology
owl:Class
Therapeutic or Preventive Procedure
Hemimandibulectomy
Partial Mandibulectomy
Hemimandibulectomy
Hemimandibulectomy
C51669
CL355148
Hemimandibulectomy
Surgery to removeone half of the mandible.
C19655
Molecular Biology Research Technique
YAC Cloning
owl:Class
Cloning
YAC Cloning
CL100414
YAC Cloning
Yeast artificial chromosomes or YAC is a vector system for cloning genomic DNA for genomic map construction and can carry from 100 to >2000 kb of foreign DNA.
YAC Cloning System
YAC Cloning
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Laboratory Test Terminology by Name
CL384365
Albumin to Globulin Ratio Measurement
Albumin/Globulin
owl:Class
Serum Chemistry Measurement
<def-definition>The ratio of albumin to globulin in a blood specimen.</def-definition><def-source>CDISC</def-source>
CDISC SEND Terminology
Albumin to Globulin Ratio Measurement
Albumin to Globulin Ratio Measurement
Laboratory Procedure
Albumin to Globulin Ratio Measurement
The determination of the ratio of albumin compared to globulin in a blood sample. The measurement may be expressed as a ratio or percentage.
C74894
ALBGLOB
CDISC SDTM Terminology
C74656
Sickle Cells/Erythrocytes
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Code
<def-source>CDISC</def-source><def-definition>A relative measurement (ratio or percentage) of the sickle cells (sickle shaped red blood cells) to all erythrocytes in a biological specimen.</def-definition>
Sickle Cell to Erythrocyte Ratio Measurement
CDISC SDTM Laboratory Test Terminology by Name
The determination of the ratio of sickle cells compared to all erythrocytes present in a sample. The measurement may be expressed as a ratio or percentage.
Sickle Cell to Erythrocyte Ratio Measurement
Clinical Data Interchange Standards Consortium Terminology
Sickle Cell to Erythrocyte Ratio Measurement
owl:Class
CL384349
CDISC
Sickle Cell to Erythrocyte Ratio Measurement
Blood Cell Count Ratio Measurement
SCKCERBC
CDISC SEND Terminology
CDISC SEND Terminology
Cytokine Measurement
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Name
Interleukin 2 Measurement
CDISC SDTM Terminology
CL384308
Interleukin 2 Measurement
<def-definition>A measurement of the interleukin 2 in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Laboratory Test Terminology by Code
C74816
Interleukin 2 Measurement
Interleukin 2
owl:Class
Interleukin 2 Measurement
Laboratory Procedure
The determination of the amount of interleukin 2 present in a sample.
INTLK2
Assessment
owl:Class
A systemic evaluation of the body and it&apos;s functions using visual inspection, palpation, percussion and auscultation. The purpose is to determine the presence or absence of physical signs of disease or abnormality for an individual&apos;s health assessment.
C0031809
Physical Examination
Newborn Screening
Diagnostic Procedure
Physical Examination
Medical Examination
C20989
Physical Examination
Physical
Physical Exam
Physical Assessment
Physical Examination
Behavioral, Psychological or Informational Intervention
Behavioral, Psychological or Informational Intervention
The use of behavioral conditioning, counseling, and/or education to prevent or treat disease.
CL366152
owl:Class
Health Care Activity
Behavioral, Psychological or Informational Intervention
C63474
Behavioral, Psychological or Informational Intervention
Intervention or Procedure
Decision
owl:Class
C0679006
Decision
Decision
Decision
C53285
Action
A position, opinion, or judgment reached on an issue under consideration.
Call
Activity
Removal of tissue from the right ventricle for microscopic examination.
Biopsy of Heart
Biopsy of the Right Ventricle
Procedure_Has_Partially_Excised_Anatomy some 'Right Ventricle'
owl:Class
Diagnostic Procedure
Biopsy of the Right Ventricle
C80412
Biopsy of the Right Ventricle
Biopsy of the Right Ventricle
C74673
Crystals
CDISC SEND Terminology
owl:Class
CL384715
CDISC
The determination of the presence or absence of crystals in a sample.
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Laboratory Test Terminology by Name
CRYSTALS
Crystal Present Or Absent
Crystal Growth Measurement
Crystal Present Or Absent
Clinical Data Interchange Standards Consortium Terminology
Crystal Present Or Absent
Laboratory Procedure
Crystal Present Or Absent
<def-source>CDISC</def-source><def-definition>A statement that indicates crystals were looked for and not found in a biological specimen.</def-definition>
CDISC SDTM Terminology
HVA
Laboratory Procedure
CDISC SDTM Terminology
Homovanillic Acid Measurement
C74863
The determination of the amount of homovanillic acid metabolite present in a sample.
C0202071
Homovanillic Acid
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
Homovanillic Acid Measurement
<def-definition>A measurement of the homovanillic acid metabolite in a biological specimen.</def-definition><def-source>CDISC</def-source>
Hormone Measurement
Homovanillic Acid Measurement
owl:Class
Homovanillic Acid Measurement
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Laboratory Test Terminology by Code
The determination of the number of Pappenheimer bodies in a sample.
CDISC SDTM Terminology
Pappenheimer Body Count
CDISC SEND Terminology
Pappenheimer Bodies
Pappenheimer Body Count
Laboratory Procedure
CDISC
C74616
CDISC SDTM Laboratory Test Terminology by Name
Hematology Test
<def-source>CDISC</def-source><def-definition>A measurement of the Pappenheimer Bodies (violet or blue staining, ferritin granules usually found along the periphery of the red blood cells) in a biological specimen.</def-definition>
Pappenheimer Body Count
Clinical Data Interchange Standards Consortium Terminology
owl:Class
Pappenheimer Body Count
PAPPEN
CL384760
Lithotripsy
owl:Class
Therapeutic Procedure
C51994
Lithotripsy
Lithotripsy
Lithotripsy
A procedure to break a stone into small particles that can be more easily cleared from the body.
Therapeutic or Preventive Procedure
C0023878
C64469
The quantitative determination of bacterial populations. The two most widely used methods for determining bacterial numbers are: 1) the standard, or viable, plate count method and 2) spectrophotometric (turbidimetric) analysis.
BACT
Bacteria
Clinical Data Interchange Standards Consortium Terminology
Bacterial Count
CL384791
CDISC
CDISC SDTM Laboratory Test Terminology by Name
Bacterial Count
Microbial Colony Count
owl:Class
CDISC SDTM Terminology
CDISC SEND Terminology
Bacterial Count
CDISC SDTM Laboratory Test Terminology by Code
<def-source>CDISC</def-source><def-definition>A measurement of the bacteria in a biological specimen.</def-definition>
Laboratory Procedure
Bacterial Count
Tobacco Use Basic Biological Research
Tobacco Use Basic Biological Research
Basic Science Research
Tobacco Use Basic Biological Research
Tobacco Use Basic Biological Research
Research Activity
owl:Class
CL003967
Laboratory-based research studies that assess the effects of tobacco and tobacco products on cell biology and cellular mechanisms of action, including the role of tobacco and tobacco byproducts in the initiation and promotion of cancer and the biological. (NCI/TRIP)
C15988
ICT
CL100601
Inferential Current Treatment
Inferential Current Treatment
Electroanalgesia
A non-invasive form of electroanalgesia, based on TENS, that uses the principle of amplitude modulation to decrease the discomfort of stimulating deeper tissues when using transcutaneously applied electrical current. It is often used in physiotherapy and rehabilitation settings. (White, Li, and Chiu)
owl:Class
Inferential Current Treatment
Therapeutic or Preventive Procedure
Inferential Current Treatment
C21030
CDISC
Double-Blinded
CDISC SDTM Terminology
<def-source>CDISC</def-source><def-definition>A study in which neither the subject nor the investigator nor the research team interacting with the subject or data during the trial knows what treatment a subject is receiving. (CDISC glossary)</def-definition>
DOUBLE BLIND
Trial Blinding Schema
C0013072
<def-source>NCI-GLOSS</def-source><def-definition>A clinical trial in which neither the medical staff nor the person knows which of several possible therapies the person is receiving.</def-definition>
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment. (MSH2001)
double-blinded
Double Blind Study
Double Blind Study
Research Activity
Clinical Data Interchange Standards Consortium Terminology
Double Blind Study
Double Blind Study
owl:Class
CDISC SDTM Trial Blinding Schema Terminology
C15228
Quantitative Concept
Statistical Imputation
Worst Observation Carried Forward Imputation Technique
owl:Class
Worst Observation Carried Forward Imputation Technique
Worst Observation Carried Forward Imputation Technique
The substitution of missing data with the value the represents the worst-case value that is not missing.
C81199
Worst Observation Carried Forward Imputation Technique
C17348
Pap Smear
Papanicolaou Smear Procedure
Papanicolaou Smear Procedure
Cervical Smear Procedure
Papanicolaou Smear Procedure
Pap smear
Papanicolaou Smear Procedure
Cervical Smear Preparation
<def-source>NCI-GLOSS</def-source><def-definition>The collection of cells from the cervix for examination under a microscope. It is used to detect changes that may be cancer or may lead to cancer, and can show noncancerous conditions, such as infection or inflammation.</def-definition>
Vaginal Smears
owl:Class
Pap Smear Procedure
C0079104
Laboratory Procedure
Cytology Specimen Collection Procedure
Interaction
Interaction
Interaction
Action
C54216
CL357875
Conceptual Entity
The quality, state, or process of (two or more things) acting on each other.
Interaction
Interactive
owl:Class
immunosuppressive therapy
Immunosuppression
C0021079
<def-source>MSH2001</def-source><def-definition>Deliberate prevention or diminution of the host's immune response. It may be nonspecific as in the administration of immunosuppressive agents (drugs or radiation) or by lymphocyte depletion or may be specific as in desensitization or the simultaneous administration of antigen and immunosuppressive drugs.</def-definition>
<def-source>NCI-GLOSS</def-source><def-definition>Therapy used to decrease the body's immune response, such as drugs given to prevent transplant rejection.</def-definition>
C15261
<def-source>CSP2000</def-source><def-definition>deliberate suppression of immune system function for experimental or therapeutic purposes.</def-definition>
Immunosuppressive Therapy
Immunosuppressive Therapy
Immunosuppressive Therapy
Immunosuppressive Therapy
<def-source>NCI-GLOSS</def-source><def-definition>Suppression of the body's immune system and its ability to fight infections or disease. Immunosuppression may be deliberately induced with drugs, as in preparation for bone marrow or other organ transplantation to prevent rejection of the donor tissue. It may also result from certain diseases such as AIDS or lymphoma or from anticancer drugs.</def-definition>
Immunotherapy
Anti-Rejection Therapy
immunosuppression
owl:Class
Therapeutic or Preventive Procedure
owl:Class
Therapeutic or Preventive Procedure
Seed Implantation
C16219
CL026432
Seed Implantation
Seed Implantation
Seed Implantation
Radiation Brachytherapy
Activity
Sprinkle
Sprinkle
CL370352
Sprinkle
Instruction Imperative
Sprinkle
owl:Class
C65102
Screening Colonoscopy
owl:Class
Colonoscopy
CL371475
Screening Colonoscopy
Diagnostic Procedure
Screening Colonoscopy
Screening Colonoscopy
C67057
Screening Method
A laboratory test designed for the quantification of an organic or inorganic chemical within a biological specimen.
Clinical Pathology Procedure
Chemistry Test
Chemistry Technique
Chemistry Test
C49237
Newborn Screening
Laboratory Procedure
Chemistry Test
CL354471
owl:Class
Chemistry Test
Chemistry Measurement
Chemistry Procedure
CL003239
C15936
Qualitative Concept
Validity of Self Report
owl:Class
Validity of Self Report
Validity of Self Report
Validity of Self Report
Validation
FDR
Multiple Comparison Adjustment
False Discovery Rate
CL369085
A statistical method used for multiple testing corrections to control the expected proportion of false positives (Type I error) among rejected tests or hypotheses. It is less stringent than other mutiple testing corrections and thereby, will allow a percentage of false positives.
owl:Class
False Discovery Rate
C64214
False Discovery Rate
Quantitative Concept
False Discovery Rate
Box Plot
Box Plot Graph
Quantitative Concept
Box Plot
Dispersion
Box Plot
C53326
A graphical display of the distribution of a set of data using the median, quartiles, and the extremes of the data set. The box contains the values between the upper quartile and lower quartile, or 50% of the distribution.
CL355839
Box Plot
owl:Class
The determination of the amount of free triiodothyronine present in a sample.
Laboratory Procedure
<def-source>CDISC</def-source><def-definition>A measurement of the free triiodothyronine in a biological specimen.</def-definition>
CDISC SDTM Laboratory Test Terminology by Name
T3FR
CDISC SDTM Laboratory Test Terminology by Code
Free Triiodothyronine Measurement
C74787
Hormone Measurement
Free Triiodothyronine Measurement
Free T3
CDISC SEND Terminology
Free Triiodothyronine Measurement
CDISC SDTM Terminology
CDISC
C0519160
Clinical Data Interchange Standards Consortium Terminology
owl:Class
Free Triiodothyronine Measurement
Triiodothyronine, Free
Immunology Test
C74712
CDISC SDTM Laboratory Test Terminology by Name
CDISC
Hepatitis C Surface Antibody Measurement
Laboratory Procedure
CDISC SDTM Terminology
Clinical Data Interchange Standards Consortium Terminology
Hepatitis C Surface Antibody Measurement
Hepatitis C Virus Surface Antibody
HCSAB
<def-source>CDISC</def-source><def-definition>A measurement of the surface antibody reaction of a biological specimen to the Hepatitis C virus.</def-definition>
owl:Class
The determination of the surface antibody reaction of a sample to the Hepatitis C virus.
Hepatitis C Surface Antibody Measurement
CL384399
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Code
Hepatitis C Surface Antibody Measurement
Endoscopic Surgery
Surgical Procedure by Method
Endoscopic Surgery
Endoscopic Surgery
CL384965
owl:Class
Therapeutic or Preventive Procedure
C62734
Endoscopic Surgery
Diagnostic Procedure
Excision of Lesion of Skin
owl:Class
CL353903
Therapeutic or Preventive Procedure
Excision of Lesion of Skin
Excision of Lesion of Skin
C51892
Excision
Excision of Lesion of Skin
The act of working out the form of something (as by making a sketch or outline or plan) or the result of this activity.
Design
C43358
Design
Activity
Design
Action
CL333519
Design
owl:Class
Electromyography
Electromyography
EMG
Electromyography
Electromyography
Diagnostic Procedure
C0013839
C38056
owl:Class
A test that assesses the health of the muscles and the nerves controlling the muscles.
Diagnostic Procedure
CL364117
Serum Chemistry Measurement
Laboratory Procedure
Serum Aspartate Aminotransferase Measurement
Serum Aspartate Aminotransferase Measurement
Serum Aspartate Aminotransferase Measurement
Serum Aspartate Aminotransferase Measurement
Serum SGOT Measurement
Aspartate Aminotransferase Measurement
C61018
Serum Aspartate Transaminase Measurement
owl:Class
A quantitative measurement of the amount of aspartate aminotransferase present in a sample of serum.
Missed Dose
Patient Problem Codes FDA CDRH
owl:Class
C50429
Patient Code (Appendix B)
Missed Dose
Dose
CL354093
Missed Dose
Functional Concept
Dose, Missed
FDA
Missed Dose
Fluorescence Microscopy
Fluorescence Microscopy
Fluorescence Microscopy
owl:Class
Light Microscopy
Microscopy of specimens stained with fluorescent dye (usually fluorescein isothiocyanate) or of naturally fluorescent materials, which emit light when exposed to ultraviolet or blue light (From MSH 2001).
C16856
C0026022
Microscopy, Light, Fluorescence
Fluorescence Microscopy
Fluorescence Light Microscopy
Laboratory Procedure
C74906
Vitamin Measurement
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Terminology
C1142098
<def-definition>A measurement of the Vitamin E in a biological specimen.</def-definition><def-source>CDISC</def-source>
Tocopherol
Vitamin E
The determination of the amount of Vitamin E present in a sample.
Vitamin E Measurement
CDISC SDTM Laboratory Test Terminology by Name
Clinical Data Interchange Standards Consortium Terminology
CDISC SEND Terminology
Vitamin E Measurement
Laboratory Procedure
Vitamin E Measurement
owl:Class
VITE
Vitamin E Measurement
Dispersion
Quantitative Concept
The variation between data values in a sample.
Statistical Distribution Characteristic
Statistical Dispersion
Dispersion
Dispersion
CL356817
Dispersion
C53321
owl:Class
owl:Class
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Laboratory Test Terminology by Code
Insulin-like Growth Factor-2
Insulin Like Growth Factor-2 Measurement
CDISC SEND Terminology
Clinical Data Interchange Standards Consortium Terminology
Insulin Like Growth Factor-2 Measurement
CDISC SDTM Terminology
Hormone Measurement
Insulin Like Growth Factor-2 Measurement
CL384286
The determination of the amount of insulin-like growth factor-2 present in a sample.
Laboratory Procedure
Insulin Like Growth Factor-2 Measurement
<def-definition>A measurement of the insulin-like growth factor-2 in a biological specimen.</def-definition><def-source>CDISC</def-source>
C74865
IGF2
CL336723
Therapeutic or Preventive Procedure
Phytoestrogen Therapy
Phytoestrogen Therapy
Phytoestrogen Therapy
Phytoestrogen Therapy
owl:Class
Biologically Based Practices
C62679
Elastin
owl:Class
Elastin Staining Method
Elastin Staining Method
C1523989
Laboratory Procedure
Elastin Staining Method
ELAS
An immunohistochemical technique to detect elastin, a polymeric protein found in the connective tissue that imparts the property of elasticity to vertebrate elastic tissue.
Elastin Staining Method
Special Histology Staining Method
Elastin Staining Method
C23013
Promonocyte to Lymphocyte Ratio Measurement
Promonocyte to Lymphocyte Ratio Measurement
The determination of the ratio of promonocytes compared to all lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
owl:Class
PROMONLE
Promonocyte to Lymphocyte Ratio Measurement
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Laboratory Test Terminology by Name
Blood Cell Count Ratio Measurement
CDISC SDTM Terminology
<def-source>CDISC</def-source><def-definition>A relative measurement (ratio or percentage) of the promonocytes to all leukocytes in a biological specimen.</def-definition>
Laboratory Procedure
CL384340
CDISC
C74652
CDISC SEND Terminology
Promonocytes/Leukocytes
Promonocyte to Lymphocyte Ratio Measurement
Biphasic Helical CT
Phased Spiral CT
Two-Phase Spiral CT
Dual-Phase Spiral CT
Diagnostic Procedure
Two-Phase Spiral CT
Two-Phase Spiral CT
C19906
owl:Class
CL009732
Two-Phase Spiral CT
A type of computed tomography whereby images of two separate phases of contrast medium perfusion are taken.
<def-definition>A relative measurement (ratio or percentage) of the lactate dehydrogenase isoenzyme 5 to total lactate dehydrogenase in a biological specimen.</def-definition><def-source>CDISC</def-source>
LDH Isoenzyme 5 to LDH Ratio Measurement
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Code
LDH Isoenzyme 5 to LDH Ratio Measurement
LDH Isoenzyme 5/LDH
LDH5LDH
CDISC SEND Terminology
Protein or Enzyme Type Measurement
CDISC SDTM Terminology
The determination of the ratio of LDH isoenzyme 5 compared to total LDH present in a sample. The measurement may be expressed as a ratio or percentage.
Clinical Data Interchange Standards Consortium Terminology
owl:Class
LDH Isoenzyme 5 to LDH Ratio Measurement
CDISC SDTM Laboratory Test Terminology by Name
LDH Isoenzyme 5 to LDH Ratio Measurement
C79455
C15917
CL054252
Arterial Embolization
Therapeutic blockage of an artery by a clot of foreign material.
arterial embolization
owl:Class
Therapeutic Surgical Procedure
Arterial Embolization
<def-source>NCI-GLOSS</def-source><def-definition>(ar-TEE-ree-al EM-bo-lih-ZAY-shun) The blocking of an artery by a clot of foreign material. This can be done as treatment to block the flow of blood to a tumor.</def-definition>
Arterial Embolization
Arterial Embolization
Therapeutic or Preventive Procedure
Diagnostic Procedure
Frequency-Domain Photon Migration
FDPM
CL375799
C70940
Diagnostic Imaging
Frequency-Domain Photon Migration
Frequency-Domain Photon Migration
Frequency-Domain Photon Migration
owl:Class
Interpretive Therapy
Interpretive Therapy
C0679645
Interpretive Therapy
Therapeutic or Preventive Procedure
Interpretive Therapy
owl:Class
Psychotherapy of the Freudian school. In this form of psychotherapy, symbols from the patient's verbalizations, dreams, and interactions are interpreted for meaning in their everyday lives. Some mental health professionals find this very helpful in defining effective methods for treating chronic pain and pain syndromes.
Psychotherapy
C21056
Calibration
C69187
Calibration
owl:Class
The act of checking or adjusting (by comparison with a standard) the accuracy of a measuring instrument.
<def-source>DICOM</def-source><def-definition>Procedure used to calibrate measurements or measurement devices.</def-definition>
C0006751
Activity
Calibration
Calibration
Action
CD20 Antigen Status
Clinical Attribute
CD20 Antigen Status
CL383894
C74095
Clinical Trial Eligibility Criteria
CD20 Status
owl:Class
Determination of presence or absence of CD20 antigen.
CD20 Antigen Status
CD20 Antigen Status
owl:Class
Type II Collagen C-Telopeptide Measurement
The determination of the amount of the type II collagen C-telopeptide present in a sample.
Type II Collagen C-Telopeptide Measurement
C82040
Protein or Enzyme Type Measurement
Type II Collagen C-Telopeptide Measurement
Type II Collagen C-Telopeptide Measurement
dentur tales doses
Give of Such Doses
CL370174
Give of Such Doses
Give of Such Doses
owl:Class
d.t.d.
Activity
Instruction Imperative
Give of Such Doses
C64660
Papanicolaou Test
Pap test
Papanicolaou Test
Pap Test
Cytologic Test
Papanicolaou Test
Papanicolaou Test
Laboratory Procedure
CL354134
C51942
owl:Class
A sample of secretions and superficial cells of the body of uterus, cervix, and ovaries; examined with a microscope to detect any abnormal cells.
Diagnostic Procedure
Newborn Screening
C81278
Percent Hemoglobin C
Hemoglobin C to Total Hemoglobin Ratio Measurement
Hemoglobin C to Total Hemoglobin Ratio Measurement
Laboratory Procedure
The determination of the ratio of Hemoglobin C compared to total Hemoglobin present in a sample. The measurement may be expressed as a ratio or percentage.
Hemoglobin C to Total Hemoglobin Ratio Measurement
Hemoglobin Measurement
owl:Class
Hemoglobin C to Total Hemoglobin Ratio Measurement
CL371474
C67035
Pulsed Electromagnetic Fields Therapy
Electromagnetic-Based Therapy
Pulsed Electromagnetic Fields Therapy
owl:Class
Pulsed Electromagnetic Fields Therapy
Pulsed Electromagnetic Fields Therapy
Therapeutic or Preventive Procedure
C15868
Health Care Activity
Vaccine Development
Vaccine Related Development, AIDS
Vaccine Related Development, AIDS
Vaccine Related Development, AIDS
owl:Class
Research Activity
CL001070
Vaccine Related Development, AIDS
CDISC SEND Terminology
C74823
Interleukin 26 Measurement
owl:Class
Laboratory Procedure
Interleukin 26 Measurement
CL384304
CDISC SDTM Terminology
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Code
Cytokine Measurement
Interleukin 26 Measurement
The determination of the amount of interleukin 26 present in a sample.
Interleukin 26 Measurement
Interleukin 26
INTLK26
CDISC SDTM Laboratory Test Terminology by Name
<def-definition>A measurement of the interleukin 26 in a biological specimen.</def-definition><def-source>CDISC</def-source>
C25358
C0596130
Attributable
owl:Class
Attribution
Mental Process
Attribution
Attribution
To assign to a cause or source.
Action
Attribution
C60819
Assay
Assay
<def-source>NCI-GLOSS</def-source><def-definition>A laboratory test to find and measure the amount of a specific substance.</def-definition>
assay
owl:Class
A qualitative or quantitative analysis performed to determine the amount of a particular constituent in a sample or the biological or pharmacological potency of a drug.
Assay
Assay
Laboratory Procedure
C1510438
Mixed Category Laboratory Procedure
Liver Function Test
AST
CDISC SDTM Terminology
CDISC SEND Terminology
owl:Class
Aspartate Aminotransferase
SGOT
Laboratory Procedure
<def-source>CDISC</def-source><def-definition>A measurement of the aspartate aminotransferase in a biological specimen.</def-definition>
C64467
CDISC SDTM Laboratory Test Terminology by Name
Aspartate Aminotransferase Measurement
Aspartate Aminotransferase Measurement
A quantitative measurement of aspartate aminotransferase present in a sample.
CDISC SDTM Laboratory Test Terminology by Code
CDISC
Protein or Enzyme Type Measurement
Aspartate Aminotransferase Measurement
Aspartate Aminotransferase Measurement
Clinical Data Interchange Standards Consortium Terminology
C0201899
Method
Technique
Technique
Technique
C0449851
Technique
owl:Class
Activity
Activity
Methods
Methods and Techniques
Techniques
A practiced and regimented skill or series of actions.
C16847
Methods, Other
Technical
Myelosuppressive Therapy
Therapeutic or Preventive Procedure
Therapeutic Bone Marrow Suppression
Therapeutic Bone Marrow Suppression
Therapeutic Bone Marrow Suppression
Induction of bone marrow suppression for the treatment of disease, especially myeloproliferative disease.
CL384015
Therapeutic Bone Marrow Suppression
C15536
owl:Class
Cell Count
Cell Count
Clinical Pathology Procedure
Laboratory Procedure
C0007584
Cell Count
Cell Count
C48938
owl:Class
A procedure to determine the number of cells in a sample. Also used to mean the result of such a procedure.
Islet Cell 512 Antibody Measurement
The determination of the amount of islet cell 512 antibody present in a sample.
owl:Class
Islet Cell 512 Antibody Measurement
Islet Cell 512 Antibody Measurement
Islet Cell 512 Antibody Measurement
C81985
Immunology Test
owl:Class
Exertion or effort directed to produce or accomplish something.
Work
C0043227
Work
Occupational Activity
Labor
C74299
Work
Toil
Work
Action
CL374498
Validation of Clinical Utility of Markers
Surrogate Endpoint Validation
Surrogate Endpoint Validation
C68773
Surrogate Endpoint Validation
Health Care Activity
Surrogate Endpoint Validation
owl:Class
aerodigestive tract cancer prevention
Prevention of Aerodigestive Tract Cancer
CL030798
C15582
Prevention of Aerodigestive Tract Cancer
Prevention of Aerodigestive Tract Cancer
Cancer Prevention
owl:Class
Therapeutic or Preventive Procedure
Prevention of Aerodigestive Tract Cancer
owl:Class
Surgical removal of the fallopian tube(s) and ovary(ies).
C15323
Procedure_Has_Excised_Anatomy only 'Fallopian Tube'
salpingo-oophorectomy
Procedure_Has_Excised_Anatomy only Ovary
C0036132
Salpingo-Oophorectomy
Therapeutic or Preventive Procedure
Salpingo-Oophorectomy
Salpingo-Oophorectomy
Gynecological Surgical Procedure
<def-source>NCI-GLOSS</def-source><def-definition>(sal-PIN-go o-o-for-EK-toe-mee) Surgical removal of the fallopian tubes and ovaries.</def-definition>
Salpingo-Oophorectomy
Ovarian Ablation
Gastric Antrectomy
Gastric Antrectomy
Gastric Antrectomy
Surgical removal of the gastric antrum.
C51658
Subtotal Gastrectomy
Procedure_Has_Completely_Excised_Anatomy only 'Antrum Pylori'
Therapeutic or Preventive Procedure
owl:Class
Antrectomy
C0599482
Gastric Antrectomy
Pancreas Transplantation
Pancreas Transplantation
Pancreas Transplantation
C0030275
pancreas grafting
<def-source>MSH2001</def-source><def-definition>The transference of a pancreas from one human or animal to another.</def-definition>
owl:Class
Pancreas Transplantation
Therapeutic or Preventive Procedure
Organ Transplantation
C15293
CL032204
Dyspnea Management
Dyspnea Management
management of dyspnea
Therapeutic or Preventive Procedure
Dyspnea Management
Dyspnea Management
Treatment to manage or alleviate difficult or painful breathing or shortness of breath.
owl:Class
Supportive Care
C15738
Serum Chemistry Measurement
The capacity of iron-binding protein in serum (transferrin) to bind serum iron.
Laboratory Procedure
IBC
C25748
Iron Binding Capacity
Iron Binding Capacity
Iron Binding Capacity
C0373658
owl:Class
Iron Binding Capacity
Laboratory Procedure
Techniques based on the principles of physical and chemical science, for the study of biological problems.
C19236
owl:Class
Research Technique
CL003163
Physical Chemical Technique
Physical Chemical Technique
Physical Chemical Technique
Physical Chemical Technique
Factor VII Measurement
Factor VII Measurement
C81960
Factor VII Measurement
owl:Class
Factor VII Measurement
Coagulation Study
The determination of the amount of factor VII present in a sample.
Giant Platelet Count
C74728
CDISC SDTM Laboratory Test Terminology by Name
Clinical Data Interchange Standards Consortium Terminology
Giant Platelets
The determination of the number of giant platelets present in a sample.
CDISC SDTM Terminology
owl:Class
Laboratory Procedure
Giant Platelet Count
CDISC
CL384281
Giant Platelet Count
<def-source>CDISC</def-source><def-definition>A measurement of the giant (larger than 7um in diameter) platelets in a biological specimen.</def-definition>
Platelet Count
PLATGNT
CDISC SDTM Laboratory Test Terminology by Code
Giant Platelet Count
CDISC SEND Terminology
owl:Class
Procedure_Has_Target_Anatomy only Stomach
Procedure_Has_Target_Anatomy only Duodenum
C51758
Bypass Gastrojejunostomy
Surgical procedure in which the stomach is connected to the jejunum, bypassing the duodenum.
Bypass Gastrojejunostomy
CL353727
Bypass Gastrojejunostomy
Digestive System Surgery
Bypass Gastrojejunostomy
Therapeutic or Preventive Procedure
Bypass
Procedure_Has_Target_Anatomy only Jejunum
owl:Class
Baculovirus Expression System
An insect cell-infecting virus that is used extensively in expression systems for recombinant proteins that require eucaryotic processing systems.
Baculovirus Expression System
Molecular Biology Research Technique
CL004777
C19553
Expression Technologies for DNA and RNA
Baculovirus Expression System
Baculovirus Expression System
C64860
Electric Field Therapy
Electric Field Therapy
Electric Field Therapy
CL370162
Therapeutic or Preventive Procedure
owl:Class
Electric Field Therapy
Therapeutic Procedure
Calcium/Creatinine
owl:Class
Calcium to Creatinine Ratio Measurement
Calcium to Creatinine Ratio Measurement
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
The determination of the ratio of calcium compared to creatinine present in a sample. The measurement may be expressed as a ratio or percentage.
Laboratory Procedure
CDISC SDTM Terminology
CACREAT
CDISC SEND Terminology
Calcium to Creatinine Ratio Measurement
Calcium to Creatinine Ratio Measurement
<def-definition>A relative measurement (ratio or percentage) of the calcium to creatinine in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Laboratory Test Terminology by Name
Urine Protein Measurement
C79439
Upload
CL343784
Upload
Uploaded
owl:Class
Activity
Upload
To transfer a file or program to a central computer from a smaller computer or a computer at a remote location.
Upload
Action
C48914
C20645
helical computed tomography
Spiral CT
Spiral CT
<def-source>NCI-GLOSS</def-source><def-definition>A detailed picture of areas inside the body. The pictures are created by a computer linked to an x-ray machine that scans the body in a spiral path.</def-definition>
SCT
Helical CT
A method of computed tomography (CT) that uses continuous rotation of the X-ray tube and continuous transport of the patient through the scanning aperture that allows the rapid acquisition of a volume of CT data. Advantages over conventional CT include: rapid acquisition of a large volume of data within a single breath-hold, thus minimizing respiration artifact and misregistration between slices; the ability to reconstruct images retrospectively at any level within the scanned volume; optimization of intravenous contrast enhancement due to the short scan times; improved multi-planar and 3-D reconstruction; and the potential for radiation dose reduction. Same as helical computed tomography. (British Journal of Radiology 1994 May;67(797):436-44)
Spiral CT
spiral CT scan
Spiral Acquisition CT
Spiral CT
Diagnostic Procedure
C0860888
owl:Class
Spiral Computed Tomography
Computed Tomography
Spiral Volumetric CT
Volumetric CT
C18467
owl:Class
Digital Mammography
CL032837
Digital Mammography
Digital Mammography
Diagnostic Procedure
Digital mammography assists in the early detection of breast cancer by incorporating modern electronics and computers into x-ray mammography methods. Instead of acquiring an image on film, it is collected electronically and can be stored directly into a computer. Digital mammography is quick and has the potential to reduce patient anxiety and inconvenience. Moreover, digital mammograms are easily archived and electronically transferable, making them ideal for teaching purposes and for evaluation during long-distance telemedicine consultations.
Digital Mammography
Mammography
Cardiectomy of Stomach
Gastric Cardiectomy
CL353443
Cardiectomy
Therapeutic or Preventive Procedure
C51940
Gastric Cardiectomy
Gastric Cardiectomy
owl:Class
Subtotal Gastrectomy
Gastric Cardiectomy
Transmetatarsal Amputation of Foot
owl:Class
C51938
Amputation of Foot
Therapeutic or Preventive Procedure
Transmetatarsal Amputation of Foot
Transmetatarsal Amputation of Foot
Transmetatarsal Amputation of Foot
CL354845
owl:Class
Scanning Force Microscopy
C0242849
Atomic Force Microscopy
Atomic Force Microscopy
Laboratory Procedure
Atomic Force Microscopy
Atomic Resolution Microscopy
C17754
Atomic Force Microscopy
A technique utilizing a scanning probe to image and analyze the surface of a material with atomic-level resolution.
Laboratory Procedure
C47868
owl:Class
<def-source>NCI-GLOSS</def-source><def-definition>A procedure in which a sample of blood is examined to measure the amounts of certain substances made in the body. An abnormal amount of a substance can be a sign of disease in the organ or tissue that produces it.</def-definition>
Blood Chemistry Study
Blood Chemistry Measurement
CL341631
Blood Chemistry Measurement
Chemistry Test
Blood Chemistry Measurement
The determination of the measured concentrations of chemical constituents of the blood by assay in a clinical laboratory.
Blood Chemistry Test
Blood Chemistry Measurement
Blood Chemistry Evaluation
blood chemistry study
Dry
Action
To remove the moisture from something.
owl:Class
Dry
Dry
Activity
C80399
Dry
Biospecimen Collection Method
Method of Biospecimen Collection
Mixed Category Laboratory Procedure
C70700
owl:Class
Biospecimen Collection Method
A method or procedure by which biological material is obtained from a subject for testing, diagnostic, treatment, or research purposes.
Laboratory Procedure
CL375827
Biospecimen Collection Method
Biospecimen Collection Method
Manipulative and Body-Based Intervention Procedure
Manipulative and Body-Based Intervention Procedure
Manipulative and Body-Based Intervention Procedure
Manipulative and Body-Based Methods
C15907
Complementary or Alternative Medical Procedure
CL002440
Therapeutic or Preventive Procedure
Manipulative and Body-Based Intervention Procedure
owl:Class
Manipulative and Body-Based Systems
Manipulative and Body-Based Intervention
Procedures which rely upon movement and manipulation of the body.They focus primarily on the structures and systems of the body, including the bones and joints, the soft tissues, and the circulatory and lymphatic systems
Therapeutic Surgical Procedure
Endoscopic Surgery
Therapeutic Endoscopic Surgery
Therapeutic Endoscopic Surgery
owl:Class
CL370555
Therapeutic Endoscopic Surgery
Therapeutic or Preventive Procedure
Therapeutic Endoscopic Surgery
C65013
CL003970
Tobacco Use, Cessation Research
C15991
owl:Class
Tobacco Use, Cessation Research
Studies to test and implement interventions among groups of individuals that are designed to stop current use of tobacco. (NCI/TRIP)
Tobacco Use, Cessation Research
Tobacco Use, Cessation Research
Research Activity
Smoking and Health Research
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
C74604
Hairy Cell Count
Hairy Cells
<def-source>CDISC</def-source><def-definition>A measurement of the hairy cells (b-cell lymphocytes with hairy projections from the cytoplasm) in a biological specimen.</def-definition>
CL384393
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Code
Hairy Cell Count
Laboratory Procedure
owl:Class
Hairy Cell Count
CDISC
Atypical Lymphocyte Count
CDISC SDTM Terminology
Hairy Cell Count
The determination of the number of hairy cells present in a sample.
HAIRYCE
C16969
Laparoscopy
<def-source>NCI-GLOSS</def-source><def-definition>(lap-a-RAHS-ko-pee) The insertion of a thin, lighted tube (called a laparoscope) through the abdominal wall to inspect the inside of the abdomen and remove tissue samples.</def-definition>
owl:Class
<def-source>CSP2000</def-source><def-definition>examination of abdominal interior with a laparoscope.</def-definition>
laparoscopy
Laparoscopic
Procedure_Has_Target_Anatomy only 'Abdominal Cavity'
Laparoscopy
Diagnostic Procedure
C0031150
Laparoscopic examination of the abdominal cavity and its contents.
Laparoscopy
Therapeutic or Preventive Procedure
Laparoscopy
Endoscopic Procedure
CDISC
owl:Class
<def-source>CDISC</def-source><def-definition>A measurement of the total bilirubin in a biological specimen.</def-definition>
Total Bilirubin Measurement
CDISC SDTM Terminology
BILI
Total Bilirubin Measurement
Liver Function Test
CDISC SEND Terminology
Bilirubin is a breakdown product of hemoglobin. Total and direct bilirubin are usually measured to screen for or to monitor liver or gall bladder dysfunction. (from MedlinePlus Medical Encyclopedia)
Clinical Data Interchange Standards Consortium Terminology
Bilirubin
Total Bilirubin Measurement
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Laboratory Test Terminology by Name
C0201913
Laboratory Procedure
C38037
Total Bilirubin Measurement
Right Oophorectomy
owl:Class
CL356025
Unilateral Oophorectomy
Therapeutic or Preventive Procedure
Right Oophorectomy
Right Oophorectomy
C51602
Surgery to remove the right ovary.
Right Oophorectomy
Procedure_Has_Excised_Anatomy only 'Right Ovary'
A measurement of the range of platelet sizes in a blood specimen.
owl:Class
Platelet Distribution Width
Platelet Distribution Width
Platelet Distribution Width
Hematology Test
Platelet Distribution Width
C81962
Gold Measurement
Gold Measurement
Laboratory Procedure
Gold Measurement
owl:Class
Gold Measurement
The determination of the amount of gold present in a sample.
C80186
Chemistry Test
Scanning Tunneling Microscopy
Atomic Resolution Microscopy
C0079837
<def-definition>indirect, molecular-resolution imaging technique based on the surface tracings of a mobile probe; in contrast to AFM the probe is driven by ionic tunneling and the image therefore depends on the conductance properties of the specimen.</def-definition><def-source>CSP2000</def-source>
Laboratory Procedure
Scanning Tunneling Microscopy
STM
Microscopy, Electron Scanning Tunnel
C76127
Scanning Tunneling Microscopy
Scanning Tunneling Microscopy
owl:Class
An imaging technique that produces a view of the surface of a sample at the atomic level by detecting variations in the current between a conducting tip and the reactive elements within the sample.
<def-definition>A type of scanning probe microscopy in which a very sharp conducting needle is swept just a few angstroms above the surface of a sample. The tiny tunneling current that flows between the sample and the needle tip is measured, and from this are produced three-dimensional topographs. Due to the poor electron conductivity of most biological samples, thin metal coatings are deposited on the sample.</def-definition><def-source>MSH2001</def-source>
Shake
Instruction Imperative
Shake
Activity
Shake
Shake
owl:Class
C64646
CL370499
Image Guided Therapy
owl:Class
CL015635
Imaging Guided Therapy
Imaging Guided Therapy
Therapeutic or Preventive Procedure
Imaging Guided Therapy
C16185
Therapeutic Procedure
Imaging Guided Therapy
The use of imaging techniques to provide the basis for therapy. eg. commonly used for surgery, such tools enable surgeons to visualize internal structures through an automated overlay of 3D reconstructions of internal anatomy on top of live video views of a patient. Also used for guidance of biopsy needles. (NCI/OSP)
owl:Class
Estimation Method
Conceptual Entity
Estimation Method
Estimation Method
Newborn Screening
C81307
Statistical Technique
A description of the technique for the approximate calculation of a value.
Estimation Method
C71509
Typical-Case Sampling
CL378069
Quantitative Concept
Matched Sampling
Typical-Case Sampling
Typical-Case Sampling
Typical-Case Sampling
owl:Class
CL385079
Coefficient of Variance
Quantitative Concept
Coefficient of Variance
CV
Dispersion
The ratio of standard deviation to mean, expressed as a percentage.
Coefficient of Variation
Coefficient of Variance
C63904
owl:Class
Coefficient of Variance
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
Atriopeptin
ANP
C74886
owl:Class
CDISC SDTM Laboratory Test Terminology by Code
The determination of the amount of atrial-natriuretic peptide present in a sample.
CDISC SDTM Terminology
Atrial Natriuretic Peptide
Atrial Natriuretic Peptide Measurement
CL384371
Protein or Enzyme Type Measurement
<def-definition>A measurement of the atrial natriuretic peptide in a biological specimen.</def-definition><def-source>CDISC</def-source>
Atrial Natriuretic Peptide Measurement
Clinical Data Interchange Standards Consortium Terminology
CDISC SEND Terminology
Atrial Natriuretic Peptide Measurement
Atrial Natriuretic Peptide Measurement
owl:Class
CDISC SEND Terminology
Vitamin B6 Measurement
Vitamin Measurement
Vitamin B6 Measurement
The determination of the amount of Vitamin B6 present in a sample.
Vitamin B6
CDISC SDTM Terminology
Vitamin B6 Measurement
VITB6
C0202251
Vitamin B6 Measurement
C74901
CDISC SDTM Laboratory Test Terminology by Name
<def-definition>A measurement of the Vitamin B6 in a biological specimen.</def-definition><def-source>CDISC</def-source>
Pyridoxine
Clinical Data Interchange Standards Consortium Terminology
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Code
owl:Class
Washing out the bronchi and alveoli by flushing with a fluid.
Lavage
Diagnostic Procedure
Bronchoalveolar Lavage
C1535502
Bronchoalveolar Lavage
Bronchoalveolar Lavage
C51913
Bronchoalveolar Lavage
owl:Class
Laboratory Procedure
A centrifugation technique that utilizes photographic capability to determine the time it takes a particle to travel through a centrifuge cell under standard conditions.
Analytical Centrifugation
C18797
Fractionation, Centrifugation, Analytical
Analytical Centrifugation
Analytical Centrifugation
Analytical Centrifugation
Centrifugation
CL000400
Erythrocyte Count
C74707
Spherocyte Count
Spherocyte Count
Spherocyte Count
Spherocytes
CDISC SDTM Terminology
Laboratory Procedure
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Code
SPHERO
Clinical Data Interchange Standards Consortium Terminology
owl:Class
CDISC SDTM Laboratory Test Terminology by Name
<def-source>CDISC</def-source><def-definition>A measurement of the spherocytes (small, sphere-shaped red blood cells) in a biological specimen.</def-definition>
CDISC
The determination of the number of spherocytes present in a sample.
Spherocyte Count
CL384350
Tyrosine Crystal Measurement
CDISC SDTM Laboratory Test Terminology by Code
CL384774
C74683
Tyrosine Crystal Measurement
Tyrosine Crystal Measurement
CYTYRO
owl:Class
Crystal Growth Measurement
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
Tyrosine Crystal Measurement
Clinical Data Interchange Standards Consortium Terminology
The determination of the amount of tyrosine crystals present in a sample.
Laboratory Procedure
CDISC
Tyrosine Crystals
<def-source>CDISC</def-source><def-definition>A measurement of the triple phosphate crystals present in a biological specimen.</def-definition>
CDISC SDTM Terminology
CL384321
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
Lactate Dehydrogenase Isoenzyme 1 Measurement
Lactate Dehydrogenase Isoenzyme 1 Measurement
owl:Class
The determination of the lactate dehydrogenase isoenzyme 1 present in a sample.
Lactate Dehydrogenase Isoenzyme 1 Measurement
<def-definition>A measurement of the lactate dehydrogenase isoenzyme 1 in a biological specimen.</def-definition><def-source>CDISC</def-source>
Laboratory Procedure
CDISC SEND Terminology
C74887
LDH Isoenzyme 1
LDH1
CDISC SDTM Laboratory Test Terminology by Name
Protein or Enzyme Type Measurement
Lactate Dehydrogenase Isoenzyme 1 Measurement
CDISC SDTM Terminology
Sample Frame
Statistical Technique
Quantitative Concept
CL356540
Sampling Frame
owl:Class
Sample Frame
Sample Frame
C53192
Sample Frame
Therapeutic or Preventive Procedure
Sternotomy
Sternotomy
owl:Class
C25220
Procedure_Has_Target_Anatomy only Sternum
Incision into or through the sternum.
C0185792
Sternotomy
Thoracic Surgical Procedure
Sternotomy
C62327
Laboratory Procedure
GD-MS
GDMS
Glow Discharge Mass Spectrometry
Glow Discharge Mass Spectrometry
owl:Class
Glow Discharge Mass Spectrometry
CL364884
Spectrometry
Glow Discharge Mass Spectrometry
A mass spectrometry technique in which a solid sample is atomized and ionized by sputtering in low-pressure direct-current plasma prior to the separation and detection of the ions in a mass analyzer. This technique is utilized to analyze trace and ultra-trace elemental constituents of inorganic materials.
Laboratory Procedure
This in vitro invasion assay utilizes matrigel, a reconstituted basement membrane, to assess the ability of cells to degrade and cross tissue barriers. This "in-vitro angiogenesis assay" can be used to screen potential anti-angiogenic compounds as well as to study angiogenic pathways underlying neoplasia.
C16216
Matrigel Invasion Assay
Matrigel Invasion Assay
Carcinogenicity Test
Matirgel is considered as basement membrane and generated from EHS sarcoma. Matrigel contains not only basement membrane components (collagens, laminin, and proteoglycans) but also matrix degrading enzymes/their inhibitors and growth factors. Invasion of tumor cells into Matrigel has been used to characterize involvement of ECM receptors and matrix degrading enzymes which play roles in tumor progression. Matrix metalloproteinases (MMPs) are a family of enzymes known to degrade components of the extracellular matrix (ECM) and their activity and secretion have been implicated in tumor invasion.
CL026260
owl:Class
Matrigel Invasion Assay
Matrigel Invasion Assay
Image Guided Radiation Therapy
Imaging Guided Therapy
Radiation Therapy
owl:Class
Image Guided Radiation Therapy
Image Guided Radiation Therapy
Therapeutic or Preventive Procedure
Image Guided Radiation Therapy
CL365613
C62727
owl:Class
Parathyroid Hormone, Fragmented
CDISC SDTM Terminology
The determination of the amount of fragmented parathyroid hormone present in a sample.
<def-source>CDISC</def-source><def-definition>A measurement of the fragmented parathyroid hormone in a biological specimen.</def-definition>
Fragmented Parathyroid Hormone Measurement
Fragmented Parathyroid Hormone Measurement
CDISC SEND Terminology
CDISC
CDISC SDTM Laboratory Test Terminology by Name
Hormone Measurement
CL384279
PTHFG
Fragmented Parathyroid Hormone Measurement
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
Fragmented Parathyroid Hormone Measurement
C74784
Sleep Disorder Therapy
Therapeutic or Preventive Procedure
Supportive Care
C15541
CL030480
Sleep Disorder Therapy
Sleep Disorder Therapy
Sleep Disorder Therapy
owl:Class
Transcendental Meditation Therapy
Transcendental Meditation
<def-source>NCI-GLOSS</def-source><def-definition>A mental technique used to promote relaxation, reduce stress, and improve quality of life.</def-definition>
C15376
Transcendental Meditation Therapy
C0150814
Transcendental Meditation Therapy
Meditation Therapy
TM
Transcendental Meditation Therapy
transcendental meditation
Mental Process
owl:Class
owl:Class
Therapeutic Procedure
CL000168
Carcinogenesis, Reversion
Therapeutic or Preventive Procedure
Carcinogenesis Reversion
Carcinogenesis Reversion
C15781
Carcinogenesis Reversion
Carcinogenesis Reversion
Geometric Distribution
A discrete, statistical distribution which is described by the probability density function: p(k) = p (1-p)^(k-1). It is the discreet analog of the exponential distribution.
Geometric Distribution
Discrete Distribution
Geometric Distribution
owl:Class
C53211
Geometric Distribution
Quantitative Concept
CL355719
Osteotomy
Orthopedic Surgical Procedure
owl:Class
Therapeutic or Preventive Procedure
C51903
Osteotomy
Surgical cutting or removal of bone.
CL354764
Procedure_Has_Excised_Anatomy only Bone
Osteotomy
Osteotomy
CL030437
A specific treatment plan within a clinical trial that describes the activities a subject will be involved in as he or she progresses through the study.
Protocol Treatment Arm
owl:Class
Treatment Regimen
Protocol Treatment Arm
Research Activity
Protocol Treatment Arm
Treatment Arm
Arm
Protocol Arm
C15538
Protocol Treatment Arm
Radical Prostatectomy
CL355427
Radical Cystoprostatectomy
owl:Class
Radical Cystectomy
Therapeutic or Preventive Procedure
Radical Cystoprostatectomy
C51899
Radical Cystoprostatectomy
Radical Cystoprostatectomy
Cystoprostatectomy
Creation
C42620
Action
Creation
Created
Create
The process by which something is brought into existence; having been brought into existence.
owl:Class
Activity
C1706214
Creation
Creation
C15221
Therapeutic or Preventive Procedure
<def-source>NCI-GLOSS</def-source><def-definition>(dye-AL-ih-sis) The process of cleansing the blood when the kidneys are not able to filter the blood.</def-definition>
C0011946
dialysis
A procedure to remove toxic substances from the blood that is used in patients with end-stage chronic kidney disease or acute kidney failure.
owl:Class
Dialysis Therapy
Dialysis
Dialysis Procedure
Dialysis
Dialysis
Dialysis
Blood Treatment
Phosphate to Creatinine Ratio Measurement
Laboratory Procedure
Clinical Data Interchange Standards Consortium Terminology
<def-definition>A relative measurement (ratio or percentage) of the phosphate to creatinine in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Laboratory Test Terminology by Name
Phosphate/Creatinine
Phosphate to Creatinine Ratio Measurement
Urine Protein Measurement
C79461
The determination of the ratio of phosphate compared to creatinine present in a sample. The measurement may be expressed as a ratio or percentage.
CDISC SEND Terminology
CDISC SDTM Terminology
owl:Class
Phosphate to Creatinine Ratio Measurement
CDISC SDTM Laboratory Test Terminology by Code
Phosphate to Creatinine Ratio Measurement
PHOSCRT
C70617
Laboratory Procedure
Total Complement Assay
Total Complement Assay
Immunology Test
An assay to determine total complement levels as a measure of complement system activation. The complement system is a major component of innate immunity against microbes and a complement to humoral, antibody-triggered responses by the body.
owl:Class
CL376057
Total Complement Assay
Total Complement Assay
Compartmental Treatment
Therapeutic or Preventive Procedure
CL014940
owl:Class
Compartmental Treatment
Compartmental Treatment
C16174
Compartmental Treatment
Local Therapy
The process of formulating general concepts by abstracting common properties of instances; reasoning from detailed facts to general principles.
Generalization
C54202
Generalization
Generalization
owl:Class
Action
Activity
C0017324
Generalization
owl:Class
Gender/Minority Enrollment
Gender/Minority Enrollment
CL004472
Gender/Minority Enrollment
Governmental or Regulatory Activity
C19502
Gender/Minority Enrollment
Outreach programs for the recruitment of women and members of minority groups as subjects in projects of clinical research. (from NIH Guidelines on the Inclusion of Women and Minorities as Subjects in Clinical Research)
Administrative Activity
owl:Class
Cardiovascular Surgical Procedure
Cardiac Therapeutic Procedure
C50825
Procedure_Has_Completely_Excised_Anatomy only 'Mitral Valve'
Mitral Valve Replacement
Mitral Valve Replacement
Mitral Valve Replacement
Therapeutic or Preventive Procedure
Surgery performed with the purpose of replacing a degenerated, calcified, malformed, dysfunctional, etc. mitral valve with bioprosthetic, homograft or autograft valve.
C0026268
Mitral Valve Replacement
Craniospinal Axis Irradiation in Children
Clinical Attribute
Extensive Radiation
Craniospinal Axis Irradiation in Children
Craniospinal Axis Irradiation in Children
C16117
CL009504
Prior Extensive Radiation
owl:Class
Craniospinal Axis Irradiation in Children
in vitro Assay
CL003586
Basic Science Research
in vitro Assay
in vitro Assay
Laboratory Procedure
Research Activity
in vitro Assay
C15958
owl:Class
Assay conducted in an artificial environment, such as in a test tube, under a defined and controlled set of solvent and solute conditions.
NAG
N-Acetyl Glucosamide Measurement
CDISC SDTM Laboratory Test Terminology by Name
<def-definition>A measurement of N-acetyl glucosamide in a biological specimen.</def-definition><def-source>CDISC</def-source>
N-Acetyl Glucosamide Measurement
N-Acetyl Glucosamine
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Terminology
N-Acetyl Glucosamide
CDISC SDTM Laboratory Test Terminology by Code
Laboratory Procedure
N-Acetyl Glucosamide Measurement
The determination of the amount of N-acetyl glucosamide present in a sample.
C79459
owl:Class
Protein or Enzyme Type Measurement
CDISC SEND Terminology
N-Acetyl Glucosamide Measurement
Gel Shift Assay
C19362
A molecular biology technique used to detect the interaction of a DNA binding protein with its cognate binding sequence. Labeled DNAs were reacted with crude cell extracts and the complexes are run through a non-denaturing polyacrylamide gel. The migration of the labeled DNA through the gel will be slower by being bound. This shift in electrophoretic mobility indicates functional binding between the protein and the DNA.
Electrophoretic Mobility Shift Assay
Electrophoretic Mobility Shift Assay
Molecular Analysis
owl:Class
CL004022
EMSA
Laboratory Procedure
Electrophoretic Mobility Shift Assay
Electrophoretic Mobility Shift Assay
Complementary or Alternative Medical Procedure
Biologically Based Practices
Biologically Based Practices
CL001244
A major category of Complementary and Alternative Medicine (CAM), dealing with natural and biologically-based nutritional interventions and practices. These include, but is not limited to, botanicals, animal-derived extracts, vitamins, minerals, fatty acids, amino acids, proteins, prebiotics and probiotics (live bacteria (and sometimes yeasts) found in foods such as yogurt or in dietary supplements), whole diets, and functional foods.
Biologically Based Practices
Biologically Based Practices
C61370
Nutritional Therapy
Therapeutic or Preventive Procedure
CAM Nutritional Therapy
Biological Based Therapies (with ODS)
owl:Class
Biologically Based Therapy
CAM Biologically-Based Therapy
Biologically-Based Therapy
Energy Therapy
Energy Therapy
C16206
owl:Class
Energy Therapy
Energy Therapy
CL024615
Therapeutic or Preventive Procedure
Complementary or Alternative Medical Procedure
Theta Glutathione S-Transferase Measurement
Protein or Enzyme Type Measurement
owl:Class
C80207
Theta Glutathione S-Transferase Measurement
Theta Glutathione S-Transferase Measurement
Laboratory Procedure
Theta Glutathione S-Transferase Measurement
The determination of the amount of Theta glutathione-s-transferase present in a sample.
Dietary Macronutrients Therapy
owl:Class
Dietary Macronutrients Therapy
Dietary Macronutrients Therapy
Dietary Macronutrients Therapy
C67026
Therapeutic or Preventive Procedure
CL371411
Biologically Based Practices
Walking
owl:Class
Walking
C73554
Walking
The act of traveling by foot.
C0080331
Daily or Recreational Activity
Walking
Physical Activity
Chemosensitization/Potentiation Therapy
owl:Class
CL366165
Drug Modulation Therapy
Therapeutic or Preventive Procedure
Chemosensitization/Potentiation Therapy
Chemosensitization/Potentiation Therapy
Chemosensitization/Potentiation Therapy
C63493
Combinatorial Synthesis of Small Molecules
Activity
owl:Class
Combinatorial Synthesis
C20063
Technique for making and testing many complex materials in parallel: computer guided synthesis in which all possible combinations are made. Combinatorial synthesis is not random, but systematic and repetitive, using sets of chemical "building blocks" to form a diverse set of molecular entities. Initial synthesis is usually made on a solid substrate. The technique lays down the materials in a checkerboard arrangement, as thin squares arranged in a grid. Scientists use combinatorial chemistry to create large populations of molecules, or libraries, that can be screened efficiently en masse. (NCI/OSP)
Combinatorial Synthesis of Small Molecules
Combinatorial Synthesis of Small Molecules
CL015631
Combinatorial Synthesis of Small Molecules
Density Gradient Centrifugation
C16411
owl:Class
Fractionation, Density Gradient
Density Gradient Centrifugation
Centrifugation
Laboratory Procedure
A method of separating macromolecules by either their differential rate of sedimentation in a centrifugal gradient or their differential buoyancy in a density gradient. (from biology-text.com)
C0007704
Density Gradient Centrifugation
Density Gradient Centrifugation
owl:Class
Paired t-Test
Paired t-Test
C53232
Paired t-Test
Paired t-Test
Quantitative Concept
t-Test
CL356499
Excision of Bone
CL353348
Therapeutic or Preventive Procedure
Excision of Bone
Excision of Bone
owl:Class
C51917
Excision
Excision of Bone
GVHD prophylaxis/therapy
C15448
Immunotherapy
Graft Versus Host Disease Prophylaxis/Therapy
Therapeutic or Preventive Procedure
Graft Versus Host Disease Prophylaxis/Therapy
Graft Versus Host Disease Prophylaxis/Therapy
C0278845
Graft Versus Host Disease Prophylaxis/Therapy
owl:Class
C54536
Molecular Genetic Technique
Immunofixation
Molecular Biology Research Technique
Immunofixation
Immunofixation
Immunofixation
C0430292
owl:Class
An enhancement of immunoelectrophoresis in which a series of post-electrophoretic gel slabs are layered with cellulose-acetate gels saturated with specific antibodies. The resulting antigen-antibody complexes fixed on the second gel may then be stained, allowing sensitive and specific qualitative visual identification of paraproteins by electrophoretic position. It can be used to identify specific proteins in the blood or urine. It has greatest application in the identification and monitoring of monoclonal proteins that are produced in conditions like Waldenstom's macroglobulinaemia and multiple myeloma.
Fill
Fill
owl:Class
Activity
Filled
Execute or satisfy a request or order; supply or furnish.
Fill
CL357686
Fill
C54093
Action
Chemistry Test
owl:Class
Turbidity Measurement
CDISC
Turbidity Measurement
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
Turbidity Measurement
Turbidity Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the opacity of a biological specimen.</def-definition>
CDISC SEND Terminology
C74723
Turbidity
CDISC SDTM Terminology
CL384753
TURB
The determination of the opacity of a sample.
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
Statistical Modeling
C16869
Activity
Statistical Modeling
Statistical Modeling
<def-source>MSH2001</def-source><def-definition>Statistical formulations or analyses which, when applied to data and found to fit the data, are then used to verify the assumptions and parameters used in the analysis. Examples of statistical models are the linear model, binomial model, polynomial model, two-parameter model, etc.</def-definition>
Statistical formulations or analyses which, when applied to data and found to fit the data, are then used to verify the assumptions and parameters used in the analysis. Examples of statistical models are the linear model, binomial model, polynomial model, two-parameter model, etc.
owl:Class
Statistical Modeling
C0026348
Computer Modeling
owl:Class
intervention, dietary
CL029013
Nutritional Intervention
Dietary Modification
Nutritional Interventions
Nutrition Intervention
Nutrition Interventions
Dietary Intervention
Therapeutic or Preventive Procedure
Dietary Intervention
C15447
Dietary Intervention
Dietary Intervention
Myelosuppressive Therapy
Therapeutic or Preventive Procedure
myelosuppressive therapy
Myelosuppressive Therapy
Myelosuppressive Therapy
Myelosuppressive Therapy
Therapeutic Procedure
<def-source>NCI-GLOSS</def-source><def-definition>Treatment that inhibits blood cell production.</def-definition>
CL031837
C15690
owl:Class
Therapeutic or Preventive Procedure
owl:Class
Adenoidectomy
Head and Neck Surgery
Adenoidectomy
Excision of Pharyngeal Tonsil
C0001425
Adenoidectomy
Procedure_Has_Excised_Anatomy only 'Pharyngeal Tonsil'
Adenoidectomy
Surgical removal of the pharyngeal tonsils (adenoids).
C51697
Sex
Sexual
Individual Behavior
owl:Class
C0036864
Sexually
Sex Behavior
Personal Behavior
Sexual Behavior
Sex Behavior
Sex Behavior
C17127
Sex Behavior
A form of physical intimacy that can be directed to reproduction (one possible goal of sexual intercourse) and/or to enjoying the body of someone else; activities associated with sexual intercourse.
Action
Activity
Discipline
Discipline
Discipline
Activities designed to promote appropriate behavior, conduct, or action including time out, limits, and controls.
C0237070
owl:Class
Discipline
C17716
N-Terminal Parathyroid Hormone Measurement
N-Terminal Parathyroid Hormone Measurement
Hormone Measurement
The determination of the amount of N-terminal parathyroid hormone present in a sample.
C81966
N-Terminal Parathyroid Hormone Measurement
N-Terminal Parathyroid Hormone Measurement
owl:Class
C21026
Therapeutic or Preventive Procedure
owl:Class
Peripheral Electronic Nerve Stimulation
A minimally invasive form of electroanalgesia involving stimulation of the dermatomal bands proximal to the affected area. It is often used in the treatment of intractable chronic lower back pain, cancer pain, and other painful disorders. (from White, Li, and Chiu)
Peripheral Electronic Nerve Stimulation
Peripheral Electronic Nerve Stimulation
Peripheral Electronic Nerve Stimulation
CL100597
Electroanalgesia
PENS
Patient Care
Patient Care
Patient Care Delivery
Healthcare Activity
Patient Care
C0017313
Patient Care
The concept concerned with all aspects of providing and distributing health services to a patient population.
Health Care Activity
C15239
owl:Class
owl:Class
C0202616
Radiography
Skeletal Survey X-Ray
Diagnostic Procedure
Skeletal Survey
C38092
Skeletal Survey X-Ray
A procedure used to detect fractures, tumors, or degenerative conditions of the bone.
Skeletal Survey X-Ray
Skeletal Survey X-Ray
owl:Class
C80201
Laboratory Procedure
Pancreatic Polypeptide Measurement
Pancreatic Polypeptide Measurement
The determination of the amount of pancreatic polypeptide present in a sample.
Protein or Enzyme Type Measurement
Pancreatic Polypeptide Measurement
Pancreatic Polypeptide Measurement
Quantitative Concept
Judgement Sampling
owl:Class
C71503
Nonrandom Sampling
Judgement Sampling
CL378030
Judgement Sampling
Judgement Sampling
CAM Exercise Therapy
Therapeutic or Preventive Procedure
Exercise Therapy
CAM Exercise Therapy
owl:Class
CAM Exercise Therapy
Complementary or Alternative Medical Procedure
CAM Exercise Therapy
C64896
C0452240
DBS
owl:Class
Deep Brain Stimulation
Electroanalgesia
Deep Brain Stimulation
Therapeutic or Preventive Procedure
C21024
A highly invasive form of electroanalgesia mainly used in the management of debilitating chronic pain syndromes after all other less invasive therapeutic modalities (including SCS) have failed. (White, Li, and Chiu)
Deep Brain Stimulation
Deep Brain Stimulation
C0394162
Implanted Fiducial-Based Imaging System
Implanted Fiducial-Based Imaging System
C68948
CL374327
Health Care Activity
owl:Class
Implanted Fiducial-Based Imaging System
Diagnostic Imaging
Implanted Fiducial-Based Imaging System
Physical Chemical Technique
C62326
Laboratory Procedure
Spectrometry
A class of analytical techniques used to measure certain physical properties such as energy, mass and wavelength via the dispersion of radiant energy or particles into a spectrum.
Spectrometry
Spectrometry
owl:Class
Spectrometry
C0436196
CL008942
owl:Class
Short Oligonucleotide Mass Analysis
Short Oligonucleotide Mass Analysis
Polymorphism Analysis
Short Oligonucleotide Mass Analysis
C19826
Short Oligonucleotide Mass Analysis
Laboratory Procedure
A method to produce defined small DNA fragments from PCR products for analysis of DNA variations by mass spectrometry. (from 7th SPORE Investigators' Workshop)
Axillary Lymph Node Biopsy
Excisional Biopsy of Lymph Node
Axillary Lymph Node Biopsy
Axillary Lymph Node Biopsy
Axillary Lymph Node Biopsy
Diagnostic Procedure
owl:Class
Surgical removal of tissues from the lymph nodes located in the cavity beneath the junction of the arm and the thorax (armpit) so that a biopsy can be performed.
C62658
C0398434
Axillary Node Biopsy
C16013
CL004424
Nutrition, Dietary Components
Nutrition, Antioxidants
owl:Class
Nutrition, Antioxidants
Research Activity
Nutrition, Antioxidants
Nutrition, Antioxidants
Role of antioxidants in cancer causation or prevention and in general health.
Therapeutic or Preventive Procedure
Thrombolytic Therapy
Thrombolytic Therapy
C0040044
<def-source>MSH2001</def-source><def-definition>Use of infusions of fibrinolytic agents to destroy or dissolve thrombi in blood vessels or bypass grafts.</def-definition>
fibrinolytic therapy
Infusion Procedure
Thrombolytic Therapy
owl:Class
C15338
Thrombolytic Therapy
Large Platelets
The determination of the number of large platelets present in a sample.
CDISC
Large Platelet Count
Large Platelet Count
Laboratory Procedure
CL384749
PLATLRG
owl:Class
CDISC SDTM Terminology
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Name
Large Platelet Count
CDISC SEND Terminology
<def-source>CDISC</def-source><def-definition>A measurement of the large (between 4 um and 7um in diameter) platelets in a biological specimen.</def-definition>
Large Platelet Count
CDISC SDTM Laboratory Test Terminology by Code
C74729
Platelet Count
The radiographic examination of the bile ducts after a contrast medium has been injected.
Radiography
Cholangiography
C0008307
Diagnostic Procedure
Cholangiography
Cholangiography
C61508
owl:Class
Cholangiography
Thymectomy
owl:Class
C29894
Thymectomy
Thymectomy
Surgical removal of part or all of the thymus gland.
Thymectomy
Surgical Procedure by Site or System
Procedure_Has_Excised_Anatomy only 'Thymus Gland'
Therapeutic or Preventive Procedure
C0040071
Anesthesia Procedure
Therapeutic or Preventive Procedure
General Anesthesia Procedure
C0002915
owl:Class
Newborn Screening
C64380
General Anesthesia Procedure
General Anesthesia
General Anesthesia Procedure
General Anesthesia Procedure
Actions that render a patient unconscious for the purpose of performing a diagnostic or interventional procedure.
Activity
C1621583
Administer
owl:Class
Administer
Administer
C64912
Instruction Imperative
Administer
To dispense, apply, or tender something to another, such as administering a medicine.
CL370585
Activity
Add
owl:Class
Add
Instruction Imperative
C64911
Add
To join or unite with others so as to increase size, quantity, or scope.
Add
Addition
Health Care Delivery Study
The Health Care Delivery Study is one that focuses on economic and social effects of health care practice and delivery.
CL323517
Health Care Delivery Study
Health Care Delivery Study
C39416
Population Study
Health Care Delivery Study
Research Activity
owl:Class
Loss of Heterozygosity Analysis
Loss of Heterozygosity Analysis
C63330
Molecular Analysis
Laboratory Procedure
Loss of Heterozygosity Analysis
CL365382
Loss of Heterozygosity Analysis
owl:Class
TENS
Transcutaneous Electrical Nerve Stimulation
Transcutaneous Electrical Nerve Stimulation
<def-source>NCI-GLOSS</def-source><def-definition>TENS. A technique in which mild electric currents are applied to some areas of the skin by a small power pack connected to two electrodes.</def-definition>
C21032
<def-source>NCI-GLOSS</def-source><def-definition>Transcutaneous electric nerve stimulation. A technique in which mild electric currents are applied to some areas of the skin by a small power pack connected to two electrodes.</def-definition>
Electroanalgesia
C0040654
Transcutaneous Electrical Nerve Stimulation
A non-invasive form of electroanalgesia that uses conductive gel pads to transmit electrical energy from an external stimulator to peripheral nerves. There are two forms: low-intensity/high frequency and high-intensity/low frequency (dense disperse). The method of action is suspected to involve release of endogenous opioids. It is often used for peripheral neuropathic pain. (from White, Li, and Chiu)
Therapeutic or Preventive Procedure
owl:Class
transcutaneous electric nerve stimulation
Transcutaneous Electrical Nerve Stimulation
Egg Preservation
C18759
Biologic Sample Preservation Procedure
owl:Class
Laboratory Procedure
CL000340
Egg Preservation
Methods for preserving egg cells such as oocyte cryopreservation in liquid nitrogen.
Egg Preservation
Egg Preservation
C82029
Protein or Enzyme Type Measurement
Polymorphonuclear Pancreatic Elastase Measurement
owl:Class
Polymorphonuclear Pancreatic Elastase Measurement
Polymorphonuclear Pancreatic Elastase Measurement
Polymorphonuclear Pancreatic Elastase Measurement
The determination of the amount of polymorphonuclear pancreatic elastase present in a sample.
Replacement Of Lens
owl:Class
Replacement Of Lens
Replacement Of Lens
Procedure_Has_Completely_Excised_Anatomy only Lens
Therapeutic or Preventive Procedure
Replacement Of Lens
Ophthalmologic Surgical Procedure
C50836
CL355451
owl:Class
Endometrial Biopsy
Endometrial Biopsy
Endometrial Biopsy
C51920
Endometrial Biopsy
Removal of tissue from the endometrial cavity for microscopic examination.
C1510477
Diagnostic Procedure
Procedure_Has_Partially_Excised_Anatomy only Endometrium
Biopsy
C80171
Laboratory Procedure
Lipid Measurement
Cholesterol to HDL-Cholesterol Ratio Measurement
Cholesterol to HDL-Cholesterol Ratio Measurement
Cholesterol to HDL-Cholesterol Ratio Measurement
The determination of the ratio of total cholesterol compared to high-density lipoprotein type cholesterol present in a sample. The measurement may be expressed as a ratio or percentage.
Cholesterol to HDL-Cholesterol Ratio Measurement
owl:Class
C81961
owl:Class
Factor VIII Measurement
Factor VIII Measurement
The determination of the amount of factor VIII present in a sample.
Coagulation Study
Factor VIII Measurement
Factor VIII Measurement
CDISC SDTM Terminology
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Code
Somatotrophin Measurement
Somatotrophin Measurement
Clinical Data Interchange Standards Consortium Terminology
CDISC SEND Terminology
<def-definition>A measurement of the somatotrophin (growth) hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC
Somatotrophin Measurement
Somatotrophin Measurement
C80360
Growth Hormone
Growth Hormone Measurement
The determination of the amount of somatotrophin present in a sample.
Somatotrophin
CDISC SDTM Laboratory Test Terminology by Name
SOMATRO
owl:Class
owl:Class
Comparative Genomic Hybridization
<def-source>CSP2000</def-source><def-definition>technique which produces a map of DNA sequence copy number as a function of chromosomal location throughout the entire genetic genome, and allows the detection of genetic deletions, duplications, and amplifications.</def-definition>
Comparative Genome Hybridization
Comparative Genomic Analysis
Comparative Genomic Hybridization
Comparative Genomic Hybridization
CGH
Comparative genomic hybridization (CGH) is a technique that allows the detection of losses and gains in DNA copy number across the entire genome without prior knowledge of specific chromosomal abnormalities. Comparative genomic hybridization utilizes the hybridization of differentially labeled tumor and reference DNA to generate a map of DNA copy number changes in tumor genomes. Comparative genomic hybridization is an ideal tool for analyzing chromosomal imbalances in archived tumor material and for examining possible correlations between these findings and tumor phenotypes. (from Ried et al. J Mol Med 1997 75:801-14)
Laboratory Procedure
Cytogenetic Analysis
Comparative Genomic Hybridization
C0796358
C18084
DNase-I Footprinting
CL009610
DNA Footprinting
DNase-I Footprinting
Molecular Biology Research Technique
A DNA footprinting method which is commonly used for analyzing specific protein-DNA interactions. In this technique, a restriction fragment containing a specific binding site is labeled at one end and digested with DNAseI. The result is a ladder of bands, representing the various sites at which DNase I cuts. The distribution of radioactivity is visualized by autoradiography.
C19898
owl:Class
DNase-I Footprinting
DNase-I Footprinting
<def-definition>A measurement of the interleukin 5 in a biological specimen.</def-definition><def-source>CDISC</def-source>
Interleukin 5 Measurement
CDISC SDTM Terminology
CL384315
CDISC SDTM Laboratory Test Terminology by Code
Laboratory Procedure
INTLK5
The determination of the amount of interleukin 5 present in a sample.
Interleukin 5 Measurement
C74833
Interleukin 5
owl:Class
Interleukin 5 Measurement
Clinical Data Interchange Standards Consortium Terminology
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Name
Interleukin 5 Measurement
Cytokine Measurement
cauterization
Surgical Procedure by Method
Cauterization
owl:Class
C0007471
Cauterization
Cauterization
cauterize
cautery
Cauterization
Cauterize
<def-source>NCI-GLOSS</def-source><def-definition>(KAW-ter-ih-ZAY-shun) The destruction of tissue with a hot instrument, an electrical current, or a caustic substance.</def-definition>
Therapeutic or Preventive Procedure
C15199
Cooking Practices
Individual Behavior
owl:Class
CL008695
Cooking Practices
Cooking Practices
Personal Behavior
C19733
Methods of preparing foods and their role in health and disease.
Cooking Methods
Cooking Practices
Individual Behavior
C0085762
Alcohol Abuse
Alcohol Abuse
C20701
Alcohol Abuse
Substance Abuse
Alcohol Abuse
The use of alcoholic beverages to excess, either on individual occasions ("binge drinking") or as a regular practice.
owl:Class
Execution
Execution
Execution
C48293
Executed
owl:Class
Execution
Activity
Action
CL342787
The act of carrying out some order or instruction to accomplish an aim.
Execute
4A's Treatment Protocol
CL014527
4A's Treatment Strategy
4As Treatment Strategy
4A's Treatment Protocol
4A's Treatment Protocol
Therapeutic or Preventive Procedure
A smoking cessation strategy recommended by the National Cancer Institute. The first 'A' is to ask patients about their smoking status at every visit and record this information. The second 'A' is to advise smokers to quit. The third 'A' is to assist patients' cessation attempts where possible by helping them to set a quit date, providing self-help materials, prescribing pharmacological treatment, and recommending counseling. The final 'A' is to arrange follow-up contact. (from Medscape)
4A's Treatment Protocol
C16161
Smoking Cessation Intervention
4As Treatment Protocol
Treatment Regimen
owl:Class
Therapeutic or Preventive Procedure
C51754
End-to-Side Anastomosis
owl:Class
CL355095
End-to-Side Anastomosis
End-to-Side Anastomosis
Anastomosis
End-to-Side Anastomosis
Clinical trials related to the development of vaccines and therapeutics directed against AIDS-related malignancies. These trials include the following malignancies: Kaposi's sarcoma, non-Hodgkins lymphoma, other lymphomas, and lymphosarcomas.
AIDS, Clinical Trials on Patients with AIDS-Related Malignancies
AIDS, Clinical Trials on Patients with AIDS-Related Malignancies
AIDS, Clinical Trials on Patients with AIDS-Related Malignancies
C15764
CL000044
AIDS, Clinical Trials on Patients with AIDS-Related Malignancies
owl:Class
AIDS Clinical Trial
Research Activity
Management of the internal organization of the hospital.
Hospital Management
C15253
Hospital Administration
Hospital Administration
Administrative Activity
C0019948
Hospital Administration
Health Care Activity
Hospital Administration / HMO
owl:Class
Hospital Administration
Lung Perfusion Scan
C38090
Radionuclide Imaging
CL322435
owl:Class
A scan, whereby a radioactive tracer substance is injected into a vein in the arm, to highlight areas of the lungs that are not receiving enough blood. The tracer is absorbed evenly in areas of the lung where the blood flow is normal and these areas show up with the tracer distributed evenly. Areas that are not receiving enough blood show up as cold spots.
Lung Perfusion Scan
Lung Perfusion Scan
Diagnostic Procedure
Lung Perfusion Scan
Human Pharmacology Study
The Human Pharmacology Study is a clinical study that involves one or more of following activities: assesses tolerance to the agent, defines/describes pharmacokinetics and pharmacodynamics, explores drug metabolism, drugs interactions, and evaluates agent activity. The term usually refers to early clinical stages of drug development.
CL323521
Trial Type
C39421
Human Pharmacology Study
Research Activity
owl:Class
Human Pharmacology Study
Human Pharmacology Study
Prostaglandin Inhibition
CL029469
Prostaglandin Inhibition
owl:Class
Therapeutic or Preventive Procedure
Prostaglandin Inhibition
C15486
Biological Therapy
Prostaglandin Inhibition
Cystostomy
Urostomy
Therapeutic or Preventive Procedure
Vesicostomy
Procedure_Has_Target_Anatomy only Bladder
owl:Class
Cystostomy
Cystostomy
C15218
<def-source>MSH2001</def-source><def-definition>Surgical creation of an opening (stoma) for drainage of the urinary bladder.</def-definition>
C0010705
Cystostomy
Study Type
C15320
Study Design
C0035171
Research Activity
Study Design
owl:Class
Study Design
Research Activity
Study Design
Research Design
Experiment Design
A plan detailing how a study will be performed in order to represent the phenomenon under examination, to answer the research questions that have been asked, and defining the methods of data analysis. Study design is driven by research hypothesis being posed, study subject/population/sample available, logistics/resources: technology, support, networking, collaborative support, etc.
Experimental Design
C82009
Epidermal Growth Factor Measurement
Epidermal Growth Factor Measurement
Epidermal Growth Factor Measurement
The determination of the amount of epidermal growth factor present in a sample.
Protein or Enzyme Type Measurement
Epidermal Growth Factor Measurement
owl:Class
Action
Contain
Include or hold; have within or as a component.
Contain
Contain
owl:Class
Contained
C79873
Contains
Activity
Containing
Contain
C1511237
Bolus Infusion
Bolus Infusion Procedure
Bolus
owl:Class
Bolus Infusion Procedure
Bolus Infusion Procedure
Therapeutic or Preventive Procedure
bolus
A procedure in which a single dose of a pharmalogical substance is administered, generally via injection, over a short period of time.
Bolus Infusion Procedure
Infusion Technique
bolus infusion
<def-source>NCI-GLOSS</def-source><def-definition>A single dose of drug usually injected into a blood vessel over a short period of time.</def-definition>
C15678
ANDSTNDL
Laboratory Procedure
Androstenediol Metabolite Measurement
Hormone Measurement
Clinical Data Interchange Standards Consortium Terminology
Androstenediol Metabolite Measurement
Androstenediol Metabolite Measurement
Androstenediol
<def-definition>A measurement of the androstenediol metabolite in a biological specimen.</def-definition><def-source>CDISC</def-source>
owl:Class
CL384367
C74842
CDISC SDTM Laboratory Test Terminology by Name
The determination of the amount of androstenediol metabolite present in a sample.
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Code
Androstenediol Metabolite Measurement
CDISC SDTM Terminology
Her2/Neu Status
owl:Class
HER2/Neu Status Unknown
CL374452
HER2/Neu Status Unknown
Clinical Attribute
HER2/Neu Status Unknown
C68750
HER2/Neu Status Unknown
C0523498
CDISC SEND Terminology
C74844
Angiotensin I Measurement
<def-definition>A measurement of the angiotensin I hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
Clinical Data Interchange Standards Consortium Terminology
Hormone Measurement
Angiotensin I Measurement
CDISC SDTM Terminology
Angiotensin I Measurement
The determination of the amount of angiotensin I hormone present in a sample.
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Laboratory Test Terminology by Code
Laboratory Procedure
ANGTNS1
Angiotensin I Measurement
owl:Class
Angiotensin I
C52004
Brain Lobectomy
Lobectomy
Brain Lobectomy
Therapeutic or Preventive Procedure
Neurosurgical Procedure
owl:Class
CL353714
Surgical removal of a lobe of the brain.
Brain Lobectomy
Brain Lobectomy
Clinical Data Interchange Standards Consortium Terminology
CDISC SEND Terminology
Oxytocin
Oxytoxin
<def-definition>A measurement of the oxytocin hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
owl:Class
Oxytocin Measurement
Oxytocin Measurement
Hormone Measurement
C74869
CDISC SDTM Terminology
Laboratory Procedure
Oxytocin Measurement
CDISC SDTM Laboratory Test Terminology by Name
Oxytocin Measurement
CDISC SDTM Laboratory Test Terminology by Code
C0523809
OXYTOCIN
The determination of the amount of oxytocin hormone present in a sample.
Photon Correlation Spectroscopy
CL365078
Dynamic Light Scattering
PCS
A type of spectroscopy that utilizes a laser beam to irradiate a sample containing particles in suspension, resulting in light scattering. Rapid fluctuations in scattering intensity, around a mean value at a certain angle, occur because of particle diffusion and are dependent upon on particle size. The calculated correlation function yields a diffusion coefficient, for a given temperature and viscosity, which can be used to calculate particle size.
Quasi-Elastic Light Scattering
Spectroscopy
C62329
owl:Class
Photon Correlation Spectroscopy
Photon Correlation Spectroscopy
Laboratory Procedure
Photon Correlation Spectroscopy
DLS
Breast Cancer Rehabilitation
Rehabilitation
Therapeutic or Preventive Procedure
CL007255
Breast Cancer Rehabilitation
Any intervention to help breast cancer patients overcome the physical or psychological effects of their disease or its treatment.
owl:Class
Breast Cancer Rehabilitation
C16052
Breast Cancer Rehabilitation
Nutritional Assessment
Nutritional Assessment
Dietary Assessment
Healthcare Activity
C15286
Nutritional Assessment
owl:Class
Health Care Activity
C0028708
<def-source>MSH2001</def-source><def-definition>Evaluation and measurement of nutritional variables in order to assess the level of nutrition or the nutritional status of the individual. Nutrition surveys may be used in making the assessment.</def-definition>
Nutritional Assessment
<def-source>NCI-GLOSS</def-source><def-definition>A laboratory test to analyze the responsiveness of a tumor to a specific drug.</def-definition>
Assay
Chemosensitivity Assay
CL031927
A laboratory test to see how well a particular chemotherapy drug kills cancer cells. The test is done after the tumor cells are removed from the body. The assay may help in choosing the best drug or drugs for the cancer being treated.
Chemosensitivity Assay
chemosensitivity assay
Chemosensitivity Testing
C18215
Laboratory Procedure
Chemosensitivity Assay
Chemosensitivity Assay
owl:Class
Surgical removal of part or all of the vas deferens.
Therapeutic or Preventive Procedure
owl:Class
Procedure_Has_Excised_Anatomy only 'Vas Deferens'
C15348
Urogenital Surgical Procedure
vasectomy
Vasectomy
Vasectomy
<def-source>NCI-GLOSS</def-source><def-definition>(vas-EK-toe-mee) An operation to cut or tie off the two tubes that carry sperm out of the testicles.</def-definition>
Vasectomy
Vasectomy
C0042387
Brightfield Microscopy
Brightfield Analysis
Laboratory Procedure
Light Microscopy
Brightfield Microscopy
Brightfield Microscopy
Brightfield Microscopy
C19827
Brightfield microscopy is a type of light microscopy in which objects are seen against a bright background.
owl:Class
CL008945
Collaboration
Collaboration
Collaboration
owl:Class
Activity
Collaboration
C73529
Action
The process by which two or more parties work jointly towards a common goal.
C0282116
owl:Class
Therapeutic or Preventive Procedure
CL032076
peritoneal perfusion
Peritoneal Perfusion
Peritoneal Perfusion
Intraperitoneal Chemotherapy
<def-source>NCI-GLOSS</def-source><def-definition>A method of delivering fluids and drugs directly to tumors in the peritoneal cavity.</def-definition>
Peritoneal Perfusion
C15730
Perfusion
Peritoneal Perfusion
Aromatase Inhibition Therapy
aromatase inhibition
CL030149
Drug treatment to block the action of aromatases, thereby reducing estrogen biosynthesis.
Aromatase Inhibition Therapy
C15525
Aromatase Inhibition Therapy
Aromatase Inhibition Therapy
Therapeutic or Preventive Procedure
owl:Class
Aromatase Inhibition
<def-source>NCI-GLOSS</def-source><def-definition>(a-ROW-ma-tays in-hib-ISH-un) Prevention of the formation of estradiol, a female hormone, by interfering with an aromatase enzyme. Aromatase inhibition is a type of hormone therapy used in postmenopausal women who have hormone-dependent breast cancer.</def-definition>
Antiestrogen Therapy
Therapeutic Laparoscopy
Therapeutic or Preventive Procedure
Therapeutic Laparoscopy
Therapeutic Endoscopic Procedure
Therapeutic Laparoscopy
C64961
Therapeutic Laparoscopy
owl:Class
Laparoscopy
CL370557
Radical Cystectomy
C0194411
Procedure_Has_Partially_Excised_Anatomy only Urethra
Radical Cystectomy
Procedure_Has_Completely_Excised_Anatomy only Bladder
<def-source>NCI-GLOSS</def-source><def-definition>(RAD-ih-kal sis-TEK-toe-mee) Surgery to remove the bladder as well as nearby tissues and organs.</def-definition>
Radical Cystectomy
owl:Class
radical cystectomy
Complete Cystectomy
Procedure_Has_Partially_Excised_Anatomy only Ureter
C15396
Cystectomy
Therapeutic or Preventive Procedure
Radical Cystectomy
Molecular Biology Research Technique
Pulsed-Field Gel Electrophoresis
Pulsed-Field Gel Electrophoresis
Gel Electrophoresis
owl:Class
C17426
Pulsed-Field Gel Electrophoresis
Laboratory Procedure
Pulsed-field gel electrophoresis (PFGE) is a method used to separate high molecular weight linear DNA fragments that are greater than 50 kilobases (kb) in size. Fragments are separated by pulsing an electrical field across an agarose gel rather than applying the constant field used in conventional electrophoresis.
Fractionation, Pulse Field
Electrophoresis, Gel, Pulsed-Field
Pulsed-Field Gel Electrophoresis
C0085117
Performance
Action
Performance
An action that is carried out or accomplished.
Performance
CL360698
owl:Class
Performance
C60778
Activity
owl:Class
C48274
Cancer Molecular Analysis Project
Research Activity
Cancer Molecular Analysis Project
Cancer Molecular Analysis Project
Through the Cancer Molecular Analysis Project (CMAP), NCI facilitates the identification and evaluation of molecular targets by integrating comprehensive molecular characterizations of cancer and making the data and infrastructure publicly accessible. CMAP permits investigators to 1) Discover molecular targets, 2) Assess their validity and interaction with other targets, 3) Determine if there are therapeutic agents that can act on specific targets, 4) Screen for possible toxicity, and 5) Determine whether there are clinical trials evaluating these agents.
Cancer Molecular Analysis Project
CMAP
Cancer Research
CL341515
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Terminology
Partial Thromboplastin Time
Partial Thromboplastin Time
aPTT
CDISC SDTM Laboratory Test Terminology by Name
APTT
Laboratory Procedure
PTT
Activated Partial Thromboplastin Time
This is a measurement of the intrinsic pathway of coagulation. Significant deficiency in factors II, V, VIII, IX, X, XI, XII or anticoagulants will prolong PTT. (BioTech Life Science Dictionary)
Coagulation Study
CDISC SEND Terminology
Partial Thromboplastin Time
<def-source>CDISC</def-source><def-definition>A measurement of the length of time that it takes for clotting to occur when reagents are added to a plasma specimen. The test is partial due to the absence of tissue factor (Factor III) from the reaction mixture.</def-definition>
CDISC SDTM Laboratory Test Terminology by Code
owl:Class
C38462
CDISC
C0030605
Partial Thromboplastin Time
C81867
Chemokine Measurement
Chemokine Measurement
Cytokine Measurement
Chemokine Measurement
The determination of the amount of chemokine present in a sample.
Chemokine Measurement
owl:Class
Laboratory Procedure
Partial Colectomy
Partial Excision of Colon
Partial Colectomy
CL354137
Partial Resection of Colon
Surgical removal of part of the colon.
Therapeutic or Preventive Procedure
C51887
Partial Colectomy
Subtotoal Colectomy
Colectomy
Partial Colectomy
owl:Class
Procedure_Has_Partially_Excised_Anatomy only Colon
Pediatric Surgical Procedures
CL008273
Surgery performed on children.
Pediatric Surgical Procedures
Pediatric Surgical Procedures
C16078
Surgical Procedure
Pediatric Surgical Procedures
Pediatric Surgery
Therapeutic or Preventive Procedure
owl:Class
Dynamic Enhanced CT
Dynamic Enhanced CT
C19921
CL011877
owl:Class
Contrast-Enhanced Spiral CT
A type of computer tomography whereby a contrast medium is administered intravenously or orally prior to X-ray imaging.
Dynamic Contrast Material Enhanced CT
Enhanced Spiral CT
Diagnostic Procedure
Dynamic Enhanced Computed Tomography
Dynamic Enhanced CT
Spiral CT
Dynamic Contrast Enhanced Computed Tomography
Dynamic Enhanced CT
Dynamic Contrast Enhanced CT
Testing
Testing
owl:Class
Testing
C15336
Testing
A procedure for critical evaluation.
Occupational Activity
Research Activity
C0039593
The act of puffing and/or inhaling smoke from a lit cigarette, cigar, or pipe.
C0453996
Tobacco Smoking
Tobacco Smoking
Tobacco Smoking
Tobacco Smoking
Smoking
C17934
owl:Class
Individual Behavior
Smoking Behavior
Health Research Service
Health Research Service
CL003225
Health Research Service
C15933
Health Research Service
Clinical Service
Health Care Activity
owl:Class
Nutritional Study
CL331314
Diet and Nutrition
Research Activity
owl:Class
C16011
Diet and Nutrition
Epidemiology studies looking at the role of dietary patterns, foods, and nutrients or other dietary components in cancer incidence and prevention.
Diet and Nutrition
Diet and Nutrition
Cardiotoxicity Attenuation
Toxicity Attenuation
Cardiotoxicity Attenuation
CL030374
Cardiotoxicity Attenuation
Therapeutic or Preventive Procedure
owl:Class
Cardiotoxicity Attenuation
C15534
Single Agent Systemic Chemotherapy
owl:Class
CL032517
Chemotherapy Single Agent Systemic
Single Agent Systemic Chemotherapy
Clinical Attribute
Single Agent Systemic Chemotherapy
C15756
Single Agent Systemic Chemotherapy
Systemic chemotherapy with a single agent regimen. A regimen is described as a distinctive collection of agent(s) and/or modalities to be utilized together during a cycle or course of therapy. All routes of administration are acceptable as long as the agent is intended for systemic therapy.
Chemotherapy
Prior Chemotherapy
Introduction, application, and evaluation of effective and practical cancer prevention, control, and rehabilitation intervention programs in community settings.
Community Oncology and Rehabilitation
Community Oncology and Rehabilitation
CL006979
Community Oncology and Rehabilitation
Health Care Activity
Community Oncology and Rehabilitation
Community Health Service
C16047
owl:Class
Polypectomy
Complete or partial removal of a polypoid lesion from the mucosal surface.
Therapeutic or Preventive Procedure
owl:Class
Excision
Polypectomy
C0521210
Polypectomy
Polypectomy
C25349
Procedure_Has_Partially_Excised_Anatomy only Mucosa
CL000660
C15829
Outcomes and Health Services Research
Outcomes and Health Services Research
Research Activity
owl:Class
Outcomes and Health Services Research
Outcomes and Health Services Research
Research Activity
Removal of tissue from the stomach for microscopic examination, using an endoscope.
Endoscopic Biopsy
owl:Class
C51685
Procedure_Has_Partially_Excised_Anatomy only Stomach
Gastric Biopsy
Gastric Biopsy
C0192472
Diagnostic Procedure
Endoscopic Biopsy of Stomach
Gastric Biopsy
Gastric Biopsy
Biopsy of Stomach
owl:Class
CL371357
Research Activity
Nutrition, Water
Nutrition, Water
Nutrition, Dietary Components
C15349
Nutrition, Water
Nutrition, Water
Role of water in cancer causation or prevention and in general health.
owl:Class
Patient Observation
watchful waiting
C15722
Therapeutic or Preventive Procedure
C0700325
observation
<def-source>NCI-GLOSS</def-source><def-definition>The most conservative option for patient under the control of medical professional. The concept refers to the situation when patient's condition is closely monitored under assigned "precaution" level, but treatment is withheld until signs or symptoms of the disease appear or change.</def-definition>
Watchful Waiting
Observation
Healthcare Activity
Patient Observation
Patient Observation
Patient Observation
Active Surveillance
Therapeutic or Preventive Procedure
Administration of male hormones to produce a clinical effect.
owl:Class
Androgen Therapy
Androgen Therapy
C15482
Androgen Therapy
Androgen Therapy
CL029466
Endocrine Drug Therapy
CL000180
Molecular Biology Research Technique
cDNA Library Construction
owl:Class
Gene Cloning
cDNA Library Construction
cDNA Library Construction
C18685
cDNA Library Construction
Methods for building collections of cloned DNA consisting of DNA copies of all the mRNAs produced by a cell type. cDNAs are generated using reverse transcriptase and either an oligo-dT or random primer. The copies are inserted into a bacterial plasmid or bacteriophage vector. The library can be maintained as a pooled population or as an arrayed library.
Age-Adjusted Mortality Rate
C53360
Age-Adjusted Mortality Rate
CL356602
Quantitative Concept
owl:Class
The death rate, or proportion of a given population that dies, during a specified time period, statistically modified to eliminate the effect of the various age distributions.
Age-Adjusted Mortality Rate
Age-Adjusted Mortality Rate
Death Rate
owl:Class
Immunological Diagnostic Method
Method used to identify disease using laboratory techniques involving interaction of antigens with specific antibodies.
Immunological Diagnostic Method
CL031707
Immunodiagnostic Procedure
Immunological Diagnostic Method
C18193
Laboratory Procedure
Diagnostic Procedure
Immunological Diagnostic Method
owl:Class
High-Intensity Focused Ultrasound Ablation
MRI-Guided Focused Ultrasound Ablation
MRI-Guided Focused Ultrasound Ablation
Therapeutic or Preventive Procedure
MRI-Guided Focused Ultrasound Ablation
MRI-Guided Focused Ultrasound Ablation
CL365665
C62723
Quantitative Concept
C53369
CL356328
owl:Class
Net Survival
Survival
Net Survival
Net Survival
Net Survival
Stress Management Therapy
CL371560
C67032
Stress Management Therapy
owl:Class
Mind-Body Intervention Procedure
Stress Management Therapy
Stress Management Therapy
Mental Process
Phenobarbital Measurement
Phenobarbital Measurement
The determination of the amount of phenobarbital present in a sample.
owl:Class
Barbiturate Drug Class Measurement
Phenobarbital Measurement
Laboratory Procedure
C75368
C0524238
Phenobarbital Measurement
owl:Class
Social Health Service
C15854
Social Health Service
CL000920
Clinical Service
Social Health Service
Social Health Service
Health Care Activity
Scale Parameter
Statistical Distribution Characteristic
Scale Parameter
Quantitative Concept
owl:Class
Scale Parameter
CL356749
C53317
Scale Parameter
Level of Evidence
Level of Evidence
C15639
Level of Evidence
Quantitative Concept
CL031516
owl:Class
Level of Evidence
Clinical Testing
A formal ranking system of the strength of evidence linked to a reported result.
Conceptual Entity
A health/illness/pain management principle specifically directed at the management of pharmacologic agents in maximizing beneficial outcomes and minimizing unfavorable effects.
Medication Management
C0150270
Therapeutic Procedure
Analgesic Management
Therapeutic or Preventive Procedure
Pharmacologic Management
Pharmacologic Management
owl:Class
C21090
Pharmacologic Management
Pharmacologic Management
CL003603
The study in the field of restoring the ability to live and work as normally as possible after a disabling injury or illness including physical, speech, and occupational therapy. (OMS94)
owl:Class
Research Activity
Rehabilitation Study
Rehabilitation Study
Trial Indication Type
Rehabilitation Research
C15961
Rehabilitation Study
Rehabilitation Study
<def-source>MSH2001</def-source><def-definition>A coordinated international effort of researchers to map and sequence the human genome.</def-definition>
C0020125
Human Genome Project
Basic Science Research
Human Genome Project
Human Genome Project
Research Activity
Human Genome Project
owl:Class
C15254
Albumin Measurement
Laboratory Procedure
C61015
Serum Albumin Measurement
A quantitative measurement of the amount of albumin present in a sample of serum.
owl:Class
Serum Chemistry Measurement
Serum Albumin Measurement
Serum Albumin Measurement
C0523465
Serum Albumin Measurement
vid
Instruction Imperative
See
See
Perceive by sight.
See
Activity
CL370621
owl:Class
C64647
See
Abdominal Surgical Procedure
C16120
Abdominal Surgical Procedure
Surgery performed on any part of the abdominal region of the body.
Abdominal Surgical Procedure
owl:Class
Procedure_Has_Target_Anatomy only 'Abdominal Cavity'
Abdominal Surgical Procedure
CL009845
Therapeutic or Preventive Procedure
Surgical Procedure by Site or System
C51692
C0150866
Biopsy
Procedure_Has_Partially_Excised_Anatomy only Skin
owl:Class
Skin Biopsy
Removal of a portion of skin tissue, for microscopic examination.
Skin Biopsy
Biopsy of Skin
Skin Biopsy
Skin Biopsy
Diagnostic Procedure
Do Not Dilute
C66956
Do Not Dilute
Instruction Imperative
owl:Class
Activity
Do Not Dilute
CL371412
Do Not Dilute
Protein or Enzyme Type Measurement
Hydroxyproline Measurement
Laboratory Procedure
C80190
Hydroxyproline Measurement
owl:Class
Hydroxyproline Measurement
The determination of the amount of hydroxyproline present in a sample.
Hydroxyproline Measurement
Bone Alkaline Phosphatase Measurement
Laboratory Procedure
Bone Alkaline Phosphatase Measurement
Bone ALP Measurement
Bone Alkaline Phosphatase Measurement
owl:Class
Alkaline Phosphatase Measurement
C81927
Bone Alkaline Phosphatase Measurement
Tumor Cell-Derived Vaccine Therapy
Therapeutic or Preventive Procedure
Tumor Cell-Derived Vaccine Therapy
Tumor Cell-Derived Vaccine Therapy
CL365465
C63335
Vaccine Therapy
Tumor Cell-Derived Vaccine Therapy
owl:Class
Total Laryngectomy
Therapeutic or Preventive Procedure
Total Laryngectomy
Procedure_Has_Completely_Excised_Anatomy only Larynx
Laryngectomy
owl:Class
Total Laryngectomy
Surgery to completely remove the larynx.
Total Laryngectomy
CL354835
C51771
Annual Screening
C62682
Disease Screening
Annual Screening
owl:Class
Annual Screening
Diagnostic Procedure
A once yearly checking for disease in the absence of symptoms.
Annual Screening
CL035538
Laser Therapy
Phototherapy
owl:Class
C15466
Therapeutic or Preventive Procedure
Laser Therapy
<def-source>NCI-GLOSS</def-source><def-definition>The use of an intensely powerful beam of light to kill cancer cells.</def-definition>
Laser Therapy
C0279027
laser therapy
Therapy, Laser
Laser Therapy
Reprocess
Reprocess
Reprocess
To put a material that has been used through a process so that it can be used again.
owl:Class
Activity
Action
Reprocess
Reprocessed
C51989
CL356005
A phase III, randomized, placebo-controlled cancer prevention trial of >18,000 men coordinated by the Southwest Oncology Group. The trial will determine the effect of a daily dose of finasteride taken for seven years on the biopsy-proven prevalence of prostate cancer. It is scheduled to be completed in 2004.
Prostate Cancer Prevention Trial
Prostate Cancer Prevention Trial
Prostate Cancer Prevention Trial
Prostate Cancer Prevention Trial
PCPT
owl:Class
C16070
Research Activity
CL008221
Cancer Prevention Trial
Inguinal Lymphadenectomy
CL354003
Diagnostic Procedure
Therapeutic or Preventive Procedure
Surgical removal of one or more inguinal lymph nodes.
Regional Lymph Node Dissection
Inguinal Lymphadenectomy
owl:Class
Procedure_Has_Excised_Anatomy only 'Inguinal Lymph Node'
Inguinal Lymphadenectomy
Inguinal Lymphadenectomy
C51619
C82434
Structured Product Labeling Business Operation Terminology
Outsourcing Human Drug Compounding
Outsourcing Human Drug Compounding
Compounding drug dosage forms for human use under a contract by other source than the facilities that use the pharmaceutics.
Outsourcing Human Drug Compounding
Outsourcing Human Drug Compounding
Activity
OUTSOURCING HUMAN DRUG COMPOUNDING
FDA
Action
owl:Class
Cancer Prevention
C15778
owl:Class
Secondary Prevention
CL000155
Cancer Prevention, Secondary
Cancer Prevention, Secondary
Therapeutic or Preventive Procedure
Cancer Prevention, Secondary
Cancer Prevention, Secondary
Protonation
Laboratory Procedure
Protonation
The addition of a proton (H+) to an atom, molecule, or ion.
Protonation
Physical Chemical Technique
C54165
owl:Class
C0178812
Protonated
Protonation
owl:Class
Use of New Techniques
Use of New Techniques
Use of New Techniques
C15895
Occupational Activity
CL001229
Use of New Techniques
Technique Development
Record Linkage Study
Record Linkage Study
Research Activity
Record Linkage Study
A study in which data from different sources are "linked". Usually used to compile epidemiological data. The logic of record linkage is that two or more items of information about a person recorded at different times, and perhaps in different places, may be of greater value when considered together than when either is considered alone.
C15424
owl:Class
Record Linkage Study
C0242239
Data Linkage
Population Study
Computer-Aided Diagnosis
Diagnostic Procedure
CAD
The use of computers for the interpretation of medical images.
C0011905
Computer-Aided Diagnosis
Diagnosis
C63604
owl:Class
Computer-Aided Diagnosis
Computer-Aided Diagnosis
Wedge Biopsy of Liver
Wedge Biopsy
Removal of a wedge-shaped portion of theliver, for microscopic examination.
CL356156
Wedge Biopsy of Liver
Wedge Biopsy of Liver
owl:Class
Diagnostic Procedure
Wedge Biopsy of Liver
C51918
Biological Cancer Immunotherapy
Immunotherapy, Cancer, Biological
Biological Immunotherapy for Cancer
Therapeutic or Preventive Procedure
Biological Cancer Immunotherapy
Cancer Immunotherapy
Biological Cancer Immunotherapy
owl:Class
The use of biological agents to enhance the host immune system in the treatment of cancer.
Biological Cancer Immunotherapy
CL003750
C15974
Biological Immunotherapy
Follow-up
<def-source>NCI-GLOSS</def-source><def-definition>Monitoring a person's health over time after treatment. This includes keeping track of the health of people who participate in a clinical study or clinical trial for a period of time, both during the study and after the study ends.</def-definition>
CL004808
Health Care Activity
Follow-up
C16033
The process by which information about the health status of an individual is obtained after a study has officially closed; an activity that continues something that has already begun or that repeats something that has already been done.
Active Follow-up
follow-up
Follow-up
owl:Class
Healthcare Activity
Followup
Follow-up
Follow Up
Breast Cancer Detection Research
owl:Class
CL000131
Cancer Detection
Breast Cancer Detection Research
Research project involving detection of breast tumors (screening, diagnosis clinical trials), development or refinement of diagnostic techniques or devices, education or promotion of breast cancer detection.
Breast Cancer Detection Research
Diagnostic Procedure
Breast Cancer Detection
Breast Cancer Detection Research
C15775
Present
To show or display; the act of presenting something to sight or view: how something looks.
Presentation
Action
Presentation
Activity
CL385203
Presenting
Presentation
Presented
Presentation
owl:Class
C61388
CDISC SEND Terminology
owl:Class
CL384423
CDISC
POIKRBC
CDISC SDTM Laboratory Test Terminology by Name
<def-definition>A relative measurement (ratio or percentage) of the poikilocytes, or irregularly shaped erythrocytes, to all erythrocytes in a biological specimen.</def-definition><def-source>CDISC</def-source>
Poikilocyte to Erythrocyte Ratio Measurement
Poikilocyte to Erythrocyte Ratio Measurement
CDISC SDTM Terminology
Poikilocyte to Erythrocyte Ratio Measurement
The determination of the ratio of poikilocytes compared to all erythrocytes present in a sample. The measurement may be expressed as a ratio or percentage.
Poikilocytes/Erythrocytes
Blood Cell Count Ratio Measurement
C74649
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
Poikilocyte to Erythrocyte Ratio Measurement
Laboratory Procedure
CL094131
Tracheo-Esophageal Speech
Tracheoesophageal Speech
Tracheoesophageal Speech
C20681
Individual Behavior
Tracheoesophageal Speech
owl:Class
Alaryngeal Speech
Tracheoesophageal Speech
Debridement of Wound of Skin
Debridement of Ulcer
Debridement of Ulcer
Debridement of Ulcer
C51740
owl:Class
CL353317
Debridement of Ulcer
Therapeutic or Preventive Procedure
owl:Class
STAR
Study of Tamoxifen and Raloxifene
Study of Tamoxifen and Raloxifene
C16110
Study of Tamoxifen and Raloxifene
Cancer Prevention Trial
CL008799
Part of the National Surgical Adjuvant Breast and Bowel Project. A study to compare the efficacy of Tamoxifen to Raloxifene in prevention of primary breast cancer among women at high risk for the disease.
Study of Tamoxifen and Raloxifene
Research Activity
Activity
CL370156
Do Not Rinse
C65121
owl:Class
Do Not Rinse
Do Not Rinse
Instruction Imperative
Do Not Rinse
Gram Staining Method
Gram Staining Method
Gram Staining Method
C23014
C0061856
Gram Staining Method
This is a method (named after the Danish bacteriologist, Hans Christian Gram) for staining and identifying bacteria. It is based on the differential retention of a crystal violet-iodine complex within the cell membrane. Gram-positive organisms will appear blue-black or purple while Gram-negative organisms will appear red.
Laboratory Procedure
GRAM
Gram Staining Method
Special Histology Staining Method
Gram Stain
owl:Class
Exercise
C0015259
Daily or Recreational Activity
C16567
Exercise
Physical Activity
Exercise
Exercise
owl:Class
Activity that requires physical or mental exertion, especially when performed to develop or maintain fitness.
CL353582
Therapeutic or Preventive Procedure
owl:Class
Surgery involving complete or partial excision of the parotid gland.
Parotidectomy
Head and Neck Surgery
Parotidectomy
Parotidectomy
C51490
Procedure_Has_Excised_Anatomy only 'Parotid Gland'
Parotidectomy
Quantitation
The act of measuring or estimating a quantity.
owl:Class
Quantitation
CL343790
C48937
Action
Quantitation
Activity
Quantitation
Immunology Test
Antithrombin Antigen Measurement
Antithrombin Antigen Measurement
The determination of the amount of antithrombin antigen present in a sample.
Antithrombin Antigen Measurement
Antithrombin Antigen Measurement
C81977
owl:Class
owl:Class
CL356257
C53362
Direct Age Adjustment
Quantitative Concept
Direct Age Adjustment
Direct Age Adjustment
Direct Age Adjustment
Population-Based Statistic
Direct Method of Standardization
owl:Class
Combined Prevention/Cessation Research
Combined Prevention/Cessation Research
Combined Prevention/Cessation Research
Studies identifying, testing, and implementing interventions among groups of individuals that are designed to both prevent and stop current use of specific substances, such as tobacco or alcohol. (NCI/TRIP)
Research Activity
Prevention Research
Combined Prevention/Cessation Research
C15984
CL003962
KRAS Mutation Analysis
C79418
owl:Class
Mutation Analysis
KRAS Mutation Analysis
Laboratory Procedure
KRAS Mutation Analysis
KRAS Mutation Analysis
Dental Procedure
Occlusal Adjustment
Occlusal Adjustment
C62300
owl:Class
Reshaping a tooth surface to modify the dental occlusion.
Therapeutic or Preventive Procedure
Occlusal Adjustment
C0341000
Occlusal Adjustment
Laboratory Procedure
TdT-Mediated dUTP Nick End Labeling Assay
TUNEL Assay
TdT-Mediated dUTP Nick End Labeling Assay
TdT-Mediated dUTP Nick End Labeling Assay
CL008876
A method to detect apoptosis.
Molecular Analysis
C19815
owl:Class
TdT-Mediated dUTP Nick End Labeling Assay
CL369272
Discretize
C64270
Research Activity
Discretize
A method to normalize data. In this normalization process, each value subtracts the column mean and is divided by the column standard deviation.
Discretize
Discretize
owl:Class
Statistical Technique
<def-source>NCI-GLOSS</def-source><def-definition>The injection of a liquid through the anus into the large bowel.</def-definition>
Enema Administration
enema
C0014268
Enema Administration
Diagnostic Procedure
Enema
Therapeutic or Preventive Procedure
Diagnostic Procedure
Enema Injection
Enema Administration
Therapeutic Procedure
C28148
Enema Administration
owl:Class
The insertion or injection of a substance through the anus, usually for the purpose of stimulating evacuation of the bowels.
CL067621
UCB transplantation
Therapeutic or Preventive Procedure
Cord Blood Transplantation
Umbilical Cord Blood Transplantation
Hematopoietic Stem Cell Transplantation
owl:Class
<def-source>NCI-GLOSS</def-source><def-definition>The injection of umbilical cord blood to restore an individual's own blood production system suppressed by anticancer drugs, radiation therapy, or both. It is being studied in the treatment of cancer and severe blood disorders such as aplastic anemia. Cord blood contains high concentrations of stem cells needed to produce new blood cells.</def-definition>
C15640
Umbilical Cord Blood Transplantation
umbilical cord blood transplantation
Umbilical Cord Blood Transplantation
Umbilical Cord Blood Transplantation
C0422392
Screening Method
Screening Method
Screening Method
Screening Method
Disease Screening
Health Care Activity
C67056
owl:Class
Mind-Body Intervention Procedure
Mental Process
C0282333
C15316
Relaxation Therapy
Relaxation Therapy
A therapeutic regimen in which the patient is guided by the therapist into alternate relaxation and flexing of muscles throughout the body as a method of pain control. It is related to guided imagery and distraction and attention therapies.
Relaxation Therapy
owl:Class
Relaxation Therapy
Scanning Transmission Electron Microscopy
An electron microscopic technique for producing images of a surface by scanning an electron beam over the sample and measuring the electronic interactions at the interface. This technique provides highly magnified images of surface morphology.
Scanning Transmission Electron Microscopy
Laboratory Procedure
C21342
Scanning Transmission Electron Microscopy
STEM
Electron Microscopy
Scanning Transmission Electron Microscopy
owl:Class
C0162731
Bone marrow transplantation in which the donor and recipient are genetically identical.
Syngeneic Bone Marrow Transplantation
Syngeneic Bone Marrow Transplantation
owl:Class
Syngeneic Bone Marrow Transplantation
Syngeneic Bone Marrow Transplantation
C0279026
C15465
Therapeutic or Preventive Procedure
Bone Marrow Transplantation
Estrogen Receptor Status
CL029635
Unknown Status, Estrogen Receptor
owl:Class
Clinical Attribute
Estrogen Receptor Status Unknown
C15495
Estrogen Receptor Status Unknown
Estrogen Receptor Status Unknown
Estrogen Receptor Status Unknown
Promotion
Promotion
C0033414
Promotion
owl:Class
Promote
Action
Promoting
Promotion
Activity
Encouragement of the progress or growth or acceptance of something.
C61391
Baseline Removal Method
Activity
CL369065
Baseline Removal Method
Baseline Removal Method
A method which relies on identifying invariant sets of features across arrays, and using these to perform normalization.
owl:Class
Statistical Technique
Baseline Removal Method
C64238
Activity
CL370498
Send
Send
owl:Class
C64663
Instruction Imperative
Send
mitte
Send
Immunotherapy, Chemical
Chemical Immunotherapy
CL002945
Immunotherapy
Chemical Immunotherapy
Chemical Immunotherapy
Therapeutic or Preventive Procedure
owl:Class
The use of chemicals to enhance the immune system in treatment of cancer
C15918
Chemical Immunotherapy
Vegan Diet
Vegan Diet
Daily or Recreational Activity
C0344353
owl:Class
Vegan Diet
Men who eat a vegan diet have lower levels of IGF-I, a protein associated with prostate cancer. These findings suggest that a diet without meat or dairy products could reduce the risk of prostate cancer. (from Medscape)
C15630
Vegan Diet
Diet
Drug Development
Drug Development, Preclinical
Biomedical Occupation or Discipline
C15801
Drug Development, Preclinical
Drug Development, Preclinical
Drug Testing/Development, Preclinical
CL000333
Research Activity
Drug Development, Preclinical
owl:Class
Maxillectomy
Therapeutic or Preventive Procedure
C51656
Maxillectomy
Maxillectomy
Surgery to remove part or all of the maxilla.
Head and Neck Surgery
Procedure_Has_Excised_Anatomy only Maxilla
owl:Class
Maxillectomy
CL355272
Ethanol Ablation Therapy
owl:Class
C67444
Ethanol Ablation Therapy
CL371648
Ethanol Ablation Therapy
Therapeutic or Preventive Procedure
Ablation Therapy
Ethanol Ablation Therapy
Label as Such
C64662
Label as Such
Label as Such
Activity
Label as Such
owl:Class
CL370445
L.A.S.
Instruction Imperative
C15859
CL000998
Trace Element Nutrition, Fluorides
owl:Class
Trace Element Nutrition, Fluorides
Studies of the role of the trace element fluoride, obtained through diet, on general health
Research Activity
Nutrition, Trace Elements
Trace Element Nutrition, Fluorides
Trace Element Nutrition, Fluorides
Oxygen Saturation Measurement
C60832
Oxygen Content Measurement
Oxygen Saturation Measurement
Quantitative Concept
owl:Class
The determination of oxygen-hemoglobin saturation of blood either by withdrawing a sample and passing it through a classical photoelectric oximeter or by electrodes attached to some translucent part of the body like finger, earlobe, or skin fold. It includes non-invasive oxygen monitoring by pulse oximetry.
Oxygen Saturation Measurement
Hemoglobin Saturation Measurement
O2 Saturation
Oxygen Saturation
Hemoglobin Saturation
Diagnostic Procedure
Blood Oxygen Saturation
C0523807
Oxygen Saturation Measurement
Oximetry
C16781
Endoscopic examination of the larynx.
laryngoscopy
Diagnostic Procedure
Therapeutic or Preventive Procedure
<def-source>NCI-GLOSS</def-source><def-definition>(LAIR-in-GOSS-kuh-pee) Examination of the larynx (voice box) with a mirror (indirect laryngoscopy) or with a laryngoscope (direct laryngoscopy).</def-definition>
Laryngoscopy
owl:Class
Endoscopic Procedure
Procedure_Has_Target_Anatomy only Larynx
Laryngoscopy
Laryngoscopy
C0023072
Laryngoscopy
Activity
owl:Class
CL355683
Action
Allocation
Allocation
C52580
Allocation
Allocation
The distribution of resources over various time periods, products, operations, or investments.
Therapeutic Procedure
CL002476
owl:Class
Reproductive Technique
Reproductive Technique
C19166
Reproductive Technique
Techniques used in human and animal reproduction.
Therapeutic or Preventive Procedure
Reproductive Technique
<def-source>MSH2001</def-source><def-definition>Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA can be inserted into or adjacent to a cellular proto-oncogene. Insertion of the provirus can cause mutations by interrupting coding sequences or regulatory elements, or cause unregulated expression of the proto-oncogene resulting in tumor formation.</def-definition>
Insertional Mutagenesis
owl:Class
Laboratory Procedure
Insertional Mutagenesis
C17377
Mutagenesis
Insertional Mutagenesis
C0079868
Insertional Mutagenesis
Mutagenesis of DNA by the insertion of one or more bases.
Kidney Biopsy
Procedure_Has_Partially_Excised_Anatomy only Kidney
Diagnostic Procedure
Removal of tissue from the kidney, for microscopic examination.
Biopsy of Kidney
Renal Biopsy
owl:Class
C51699
Biopsy
Kidney Biopsy
CL354037
Kidney Biopsy
Kidney Biopsy
CDISC SDTM Terminology
C0524222
CDISC SEND Terminology
Oxycodone Measurement
Clinical Data Interchange Standards Consortium Terminology
C74884
Laboratory Procedure
Oxycontin
Opioid Measurement
The determination of the amount of oxycodone present in a sample.
owl:Class
CDISC SDTM Laboratory Test Terminology by Name
Oxycodone Measurement
Oxycodone Measurement
OXYCDN
CDISC SDTM Laboratory Test Terminology by Code
Oxycodone Measurement
Oxycodone
<def-definition>A measurement of the oxycodone present in a biological specimen.</def-definition><def-source>CDISC</def-source>
C51999
Angioplasty
Angioplasty
Angioplasty
Procedure_Has_Target_Anatomy only 'Blood Vessel'
Therapeutic or Preventive Procedure
Cardiovascular Surgical Procedure
An endovascular procedure used to widen diseased arteries resulting in increasing blood flow through the area.
C0162577
Angioplasty
owl:Class
CL100596
owl:Class
C21025
Peripheral Nerve Stimulation
Therapeutic or Preventive Procedure
Peripheral Nerve Stimulation
Peripheral Nerve Stimulation
PNS
A minimally invasive form of electroanalgesia often used in neuropathic pain. For best effect, the stimulation is applied proximally to the site of the nerve lesion. (from White, Li, and Chiu)
Electroanalgesia
Peripheral Nerve Stimulation
Vitamin D2 Measurement
Vitamin D2 Measurement
CDISC SDTM Terminology
Laboratory Procedure
VITD2
Vitamin D2 Measurement
CL384443
Clinical Data Interchange Standards Consortium Terminology
Vitamin Measurement
<def-definition>A measurement of the Vitamin D2 in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Code
C74904
Ergocalciferol
owl:Class
Vitamin D2
Vitamin D2 Measurement
The determination of the amount of Vitamin D2 present in a sample.
Macrophage Colony Stimulating Factor Measurement
Macrophage Colony Stimulating Factor Measurement
The determination of the amount of macrophage colony stimulating factor present in a sample.
C80191
Protein or Enzyme Type Measurement
Macrophage Colony Stimulating Factor Measurement
Laboratory Procedure
Macrophage Colony Stimulating Factor Measurement
owl:Class
owl:Class
Shaving Procedure
Shaving Procedure
Shaving Procedure
Shave Excision
Therapeutic or Preventive Procedure
C51885
Shaving Procedure
CL353668
Surgical Procedure by Method
CL370402
Instruction Imperative
Call
Call
Call
owl:Class
Send a message or attempt to reach someone by radio, phone, etc.
C64924
Call
Activity
Bypass
bypass
Surgical Procedure by Method
C15723
Bypass
owl:Class
C0185033
Bypass
Bypass
Therapeutic or Preventive Procedure
<def-source>NCI-GLOSS</def-source><def-definition>A surgical procedure in which the doctor creates a new pathway for the flow of body fluids.</def-definition>
Special Histology Staining Method
Chloroacetate Esterase Staining Method
Chloroacetate Esterase Stain
Chloroacetate Esterase Staining Method
Chloroacetate Esterase Staining Method
Chloroacetate Esterase Staining Method
C28409
Chloroacetate Esterase Staining Method
owl:Class
Chloroacetate esterase (CAE) is a cytochemical staining technique to specifically identify cells of the granulocyte lineage, from the early promyelocyte stage to mature neutrophils.
Leder Stain
C1318936
Laboratory Procedure
Choose
Choose
Choose
Activity
Chosen
Action
Choice
owl:Class
C48912
Pick
Select
Choose
CL343699
Select from a group.
Picked
Medical Castration
Endocrine Drug Therapy
Medical Castration
Therapeutic or Preventive Procedure
C15743
CL032276
owl:Class
Medical Castration
Medical Castration
<def-source>NCI-GLOSS</def-source><def-definition>Refers to the use of drugs to suppress the function of the ovaries or testicles.</def-definition>
medical castration
Reintroduction of previously withdrawn medical intervention in the same patient.
Action
C68621
CL371954
Rechallenge
Activity
Rechallenge
Rechallenge
owl:Class
Rechallenge
Bronchoscopy with Biopsy
Bronchoscopy with Biopsy
Bronchoscopy with Biopsy
Diagnostic Procedure
Procedure_Has_Partially_Excised_Anatomy only Bronchus
Removal bronchial tissue for microscopic examination, using an endoscope.
owl:Class
C51638
CL353720
Endoscopic Biopsy
Bronchoscopy with Biopsy
CL356422
owl:Class
Complete Method
C53374
Complete Method of Relative Survival Calculation
Complete Method of Relative Survival Calculation
Research Activity
Complete Method of Relative Survival Calculation
Complete Method of Relative Survival Calculation
Survival Analysis Technique
Buprenorphine Measurement
C0524040
owl:Class
C75352
Opioid Measurement
Buprenorphine Measurement
Buprenorphine Measurement
Laboratory Procedure
Buprenorphine Measurement
The determination of the amount of buprenorphine present in a sample.
Modest-Temperature Hyperthermia
Therapeutic or Preventive Procedure
CL004794
Modest-Temperature Hyperthermia
Heating of tumors to the 40.5-42.5C range. Increases the oxygenation of tumors thereby enhancing the effect of radiation therapy.
Modest-Temperature Hyperthermia
C16029
Modest-Temperature Hyperthermia
Hyperthermia Treatment
owl:Class
Mild-Temperature Hyperthermia
MTH
C16106
Nutrition, Fats, Monosaturated
Nutrition, Fats
Nutrition, Fats, Monosaturated
Nutrition, Fats, Monosaturated
owl:Class
CL008762
Nutrition, Fats, Monosaturated
Study of monosaturated fats in relation to cancer.
Research Activity
Cheilectomy
Cheilectomy
owl:Class
C51596
CL355024
Procedure_Has_Target_Anatomy only Joint
Orthopedic Surgical Procedure
Procedure_Has_Partially_Excised_Anatomy only Bone
Therapeutic or Preventive Procedure
Cheilectomy
Cheilectomy
CDISC SDTM Terminology
Choriogonadotropin Beta
Laboratory Procedure
owl:Class
Pregnancy Test
CDISC
HCG
CL370137
<def-source>CDISC</def-source><def-definition>A measurement of the Choriogonadotropin Beta in a biological specimen.</def-definition>
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
Choriogonadotropin Beta Measurement
C64851
Choriogonadotropin Beta Measurement
CDISC SDTM Laboratory Test Terminology by Code
Hormone Measurement
A determination of the presence of Choriogonadotropin Beta protein.
Choriogonadotropin Beta Measurement
Clinical Data Interchange Standards Consortium Terminology
Choriogonadotropin Beta Measurement
Supportive Care
Treatment to manage or alleviate the fatigue and weight loss often associated with cancer.
Anticachectic Therapy
owl:Class
Anticachectic Therapy
CL029687
Therapeutic or Preventive Procedure
C15506
Anticachectic Therapy
Anticachectic Therapy
CL353660
Segmental Mandibulectomy
Segmental Mandibulectomy
Therapeutic or Preventive Procedure
Surgery to remove a segment of the mandible.
Partial Mandibulectomy
C51665
Segmental Mandibulectomy
Segmental Mandibulectomy
owl:Class
owl:Class
Sonication
Laboratory Procedure
Sonication
Research Technique
A technique that uses sound energy to agitate or disrupt the components of a sample.
Sonication
Sonication
C81871
Qualitative Concept
<def-source>CDISC</def-source><def-definition>Remain in force or carry on without letup; keep or maintain in unaltered condition; exist in time or space without stop or interruption. (NCI)</def-definition>
CDISC
Clinical Data Interchange Standards Consortium Terminology
Continue
CDISC Observation Class Terminology
CDISC SDTM Terminology
CDISC SDTM Frequency Terminology
Instruction Imperative
C53279
Ongoing
ONGO
Continue
Action
C0750536
CDISC SEND Terminology
Remain in force or carry on without letup; keep or maintain in unaltered condition; exist in time or space without stop or interruption.
Continuous
Continue
owl:Class
Continue
CONTINUOUS
Continued
Continuing
Radical Nephrectomy
Radical Nephrectomy
C51778
Nephrectomy
owl:Class
C0401181
Procedure_Has_Partially_Excised_Anatomy only Ureter
Procedure_Has_Completely_Excised_Anatomy only Kidney
Procedure_May_Have_Excised_Anatomy some 'Intra-Abdominal Lymph Node'
Radical Nephrectomy
Procedure_May_Have_Excised_Anatomy some 'Adrenal Gland'
Radical Nephrectomy
Therapeutic or Preventive Procedure
Tobacco Use, Community and State Intervention Research
C15990
owl:Class
Research studies that test group and population-based interventions and the dissemination of group and population-based interventions to prevent and reduce tobacco use. (NCI/TRIP)
Tobacco Use, Community and State Intervention Research
CL003969
Tobacco Use, Community and State Intervention Research
Smoking and Health Research
Research Activity
Tobacco Use, Community and State Intervention Research
owl:Class
CL354828
Tissue Processing Technique
Laboratory Procedure
Tissue Processing Technique
C49337
Histological Procedure
Tissue Preparation
Tissue Processing Technique
Tissue Processing Technique
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
Leucine Crystal Measurement
CYLEUC
CL384750
CDISC SDTM Laboratory Test Terminology by Name
<def-source>CDISC</def-source><def-definition>A measurement of the leucine crystals present in a biological specimen.</def-definition>
CDISC
Leucine Crystal Measurement
CDISC SEND Terminology
Leucine Crystals
Crystal Growth Measurement
Laboratory Procedure
owl:Class
The determination of the amount of leucine crystals present in a sample.
Leucine Crystal Measurement
Clinical Data Interchange Standards Consortium Terminology
C74680
Leucine Crystal Measurement
Endoscopic Procedure
Endoscopic examination of the nasopharynx.
C0189025
Nasopharyngoscopy
Therapeutic or Preventive Procedure
Nasopharyngoscopy
C38075
Nasopharyngoscopy
Diagnostic Procedure
owl:Class
Procedure_Has_Target_Anatomy only Nasopharynx
Nasopharyngoscopy
Emergency Care
Emergency Care
Patient Care
C52641
C0013969
Care necessary to treat acute pain, infection, bleeding, or trauma.
Emergency Care
owl:Class
Emergency Care
Health Care Activity
C29884
owl:Class
Vaccinia Virus Study
Research Activity
Clinical Study
Vaccinia Virus Study
CL320057
Vaccinia Virus Study
Clinical Vaccinia Virus Studies employ vaccinia virus as an attenuated agent or as a vector for gene transfer. In attenuated form, Vaccinia virus can be used for protection against smallpox virus (variola) and is a highly effective immunizing agent. When genetically altered to contain human genes, Vaccinia virus can be used in cancer immunotherapy to induce immune protection against some forms of cancers. (NCI04)
Vaccinia Virus Study
The exchange of information between objects, people, or groups.
owl:Class
Communication
C16452
Behavior
Communication
C0009452
Communication
Communication
Social Behavior
Communicative
CL004044
C16003
Infectious Diseases Research
Infectious Diseases Research
Infectious Diseases Research
owl:Class
Research Activity
Infectious Diseases / Laboratory
The study of infectious diseases in the laboratory
Research Activity
Infectious Diseases Research
Technique
Technique used in the laboratory for scientific research.
CL026563
Laboratory Procedure
C20368
Research Technique
Research Technique
Research Technique
Research Technique
owl:Class
owl:Class
Disease Screening
C62693
Long-Term Screening
Long-Term Screening
Long-Term Screening
Long-Term Screening
Diagnostic Procedure
CL035537
second-look surgery
Second Look
Second-Look Surgery
Second-Look Surgery
Reoperation
owl:Class
Second-Look Surgery
<def-source>NCI-GLOSS</def-source><def-definition>Surgery performed after primary treatment to determine whether tumor cells remain.</def-definition>
Surgery performed after cancer treatment to assess the results of prior treatment and to plan possible future treatment.
Therapeutic or Preventive Procedure
Surgical Revision
Second-Look Surgery
C15317
Surgical Procedure
C0035110
Repeat Surgery
Cervical Papanicolaou Test
Cervical Papanicolaou Test
Cervical Papanicolaou Test
Cervical Pap Test
Diagnostic Procedure
C62670
Cervical Papanicolaou Test
Laboratory Procedure
CL365530
owl:Class
Papanicolaou Test
Activity
Method for identifying invariant set normalization baseline using median expression values. Defined in the documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html.
Median Baseline Removal Method
Median Baseline Removal Method
Median Baseline Removal Method
CL369327
owl:Class
Baseline Removal Method
Median Baseline Removal Method
C64240
Gynecological Surgical Procedure
gynecologic surgery
Gynecological Surgical Procedure
Therapeutic or Preventive Procedure
gynecologic surgical procedures
Procedure_Has_Target_Anatomy only 'Female Reproductive System'
Surgery performed on the female reproductive system.
owl:Class
Gynecological Surgical Procedure
Gynecological Surgical Procedure
Urogenital Surgical Procedure
C15332
C0038902
gynecological surgery
owl:Class
Intraoperative Radiation Therapy
C15623
Therapeutic or Preventive Procedure
radiotherapy, intraoperative
Intraoperative Radiation Therapy
Intraoperative Radiotherapy
Local Therapy
Radiation Therapy
<def-source>NCI-GLOSS</def-source><def-definition>Intraoperative radiation therapy. Radiation treatment aimed directly at a tumor during surgery.</def-definition>
<def-source>NCI-GLOSS</def-source><def-definition>IORT. Radiation treatment aimed directly at a tumor during surgery.</def-definition>
Intraoperative Radiation Therapy
IORT
intraoperative radiation therapy
Intraoperative Radiation Therapy
CL031293
owl:Class
Cardiac Diagnostic Procedure
A study using magnetic resonance to observe cardiac activity during the administration of pharmacologic stressors.
C80409
Stress Cardiac Magnetic Resonance Imaging
Stress Cardiac Magnetic Resonance Imaging
Magnetic Resonance Imaging
Stress Cardiac Magnetic Resonance Imaging
Diagnostic Procedure
Stress Cardiac Magnetic Resonance Imaging
Cancer Diagnostic Procedure
Cancer Diagnostic Procedure
owl:Class
C79428
Diagnostic Procedure
Cancer Diagnostic Procedure
Cancer Diagnostic Procedure
Cancer Diagnostic or Therapeutic Procedure
Diagnostic Procedure
C15861
Research Activity
Trace Element Nutrition, Other
owl:Class
Trace Element Nutrition, Other
Trace Element Nutrition, Other
Nutrition, Trace Elements
Trace Element Nutrition, Other
CL001000
C51982
CL355208
Action
Implantation
Implantation
Activity
A surgical procedure that places something in the human body.
Implantation
owl:Class
Implantation
<def-source>CDISC</def-source><def-definition>All those planned and systematic actions that are established to ensure that the trial is performed and the data are generated, documented (recorded), and reported in compliance with good clinical practice (GCP) and the applicable regulatory requirement(s). [ICH]</def-definition>
Clinical Data Interchange Standards Consortium Terminology
Quality Assurance
Programs of regular assessment of medical and nursing activities to evaluate the quality of medical care including all actions taken to ensure that standards and procedures are adhered to and that delivered products or services meet performance requirements.
Quality Assurance
owl:Class
Action
CDISC
Quality Assurance
QA
Activity
quality assurance (QA)
Clinical Data Interchange Standards Consortium Glossary Terminology
C15381
Quality Assurance
C0178932
Death Rate
Quantitative Concept
Standardized Mortality Ratio
Standardized Mortality Ratio
Standardized Mortality Ratio
C53363
owl:Class
Standardized Mortality Ratio
CL355815
The determination of the number of platelets in a blood sample, usually expressed as platelets per cubic millimeter (cmm) of whole blood.
CDISC SDTM Terminology
owl:Class
Platelet Count
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Code
Platelet
CDISC SDTM Laboratory Test Terminology by Name
<def-definition>A measurement of the platelets per unit of a biological specimen.</def-definition><def-source>CDISC</def-source>
Blood Cell Count
CDISC
C51951
PLAT
Platelet Count
Laboratory Procedure
Clinical Data Interchange Standards Consortium Terminology
CL353612
Platelet Count
Platelet Count
Code Translation
CL375970
C70898
An automated procedure that uses a specialized set of concept descriptors for conversion of the target concept descriptors into executable elements of other code systems with the equivalent semantics.
Machine Activity
owl:Class
Code Translation
Code Translation
Computational Technique
Code Translation
Support Group Therapy
CL371562
C67030
Mind-Body Intervention Procedure
Support Group Therapy
Support Group Therapy
Mental Process
Support Group Therapy
owl:Class
owl:Class
Disclosure
Action
C0012625
C51977
Disclosure
The making known of a fact that had previously been hidden; release of information.
Disclosure
Activity
Disclosure
C49663
Pharmacokinetic Study
Research Activity
PK Study
CL354156
CDISC SDTM Trial Type Terminology
Clinical Data Interchange Standards Consortium Terminology
PHARMACOKINETIC
CDISC SDTM Terminology
Pharmacokinetic Study
<def-source>CDISC</def-source><def-definition>A study of the process by which a drug is absorbed, distributed, metabolized, and eliminated by the body. (NCI)</def-definition>
Pharmacokinetic Study
CDISC
A study of the process by which a drug is absorbed, distributed, metabolized, and eliminated by the body.
Pharmacokinetic Study
Human Pharmacology Study
owl:Class
DNA Ploidy Analysis
C18303
DNA Analysis
DNA Ploidy Analysis
A test used to measure nuclear deoxyribonucleic acid content (ploidy or multiplicity of the basic number of chromosomes) in a cell.
DNA Ploidy Analysis
Molecular Biology Research Technique
owl:Class
CL032115
DNA Ploidy Analysis
Laboratory Procedure
Continuous Distribution
Chi-Square Distribution
C53225
Chi-Square Distribution
Chi-Square Distribution
C0008040
A mathematical distribution whose shape is determined by its one parameter, the degree(s) of freedom (df). This distribution is often used in inferential statistics in tests of significance.
Chi-Square Distribution
owl:Class
Quantitative Concept
Chi Square Distribution
Diagnostic Procedure
Proctoscopy
Gastrointestinal Endoscopy
owl:Class
Proctoscopy
C17012
Endoscopic examination of the rectum.
C0033251
proctoscopy
Procedure_Has_Target_Anatomy only Rectum
Proctoscopy
<def-source>NCI-GLOSS</def-source><def-definition>(prok-TOS -ko-pee) An examination of the rectum using a thin, lighted tube called a proctoscope.</def-definition>
Proctoscopy
Benzodiazepine Measurement
Benzodiazepine Measurement
C0373486
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Terminology
BNZDZPN
owl:Class
<def-definition>A measurement of any benzodiazepine class drug present in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Laboratory Test Terminology by Code
The determination of the amount of benzodiazepine class drug present in a sample.
CDISC SEND Terminology
Laboratory Procedure
Benzodiazepine Measurement
CDISC SDTM Laboratory Test Terminology by Name
Benzodiazepine
Benzodiazepine Measurement
CNS Depressant Drug Measurement
C74692
Diagnostic Procedure
Detection
Detection
Detection
C16210
C1511790
Detected
Detection
Diagnostic Procedure
The activity of perceiving, discerning, discovering or identifying.
owl:Class
Therapeutic or Preventive Procedure
owl:Class
CL371247
C66895
Physiological Support
Supportive Care
Physiological Support
Physiological Support
Physiological Support
Cardiac Therapeutic Procedure
Therapeutic or Preventive Procedure
Procedure_Has_Target_Anatomy only Pericardium
owl:Class
Pericardiostomy
Pericardial Window Procedure
Cardiovascular Surgical Procedure
Pericardial Window Procedure
Pericardial Window Procedure
Pericardial Window Procedure
C51618
CL353595
A procedure in which an opening is made in the pericardium.
Debulking
Debulking Procedure
Therapeutic or Preventive Procedure
Debulking Procedure
Debulking Procedure
Debulking Procedure
Surgical Procedure by Method
C51661
owl:Class
CL353318
Activity
owl:Class
Give
Give
Give
C64974
Give
Instruction Imperative
CL385615
Free Estriol Measurement
C81963
Free Estriol Measurement
owl:Class
Hormone Measurement
Free Estriol Measurement
Free Estriol Measurement
The determination of the amount of free estriol present in a sample.
Cancer Control Science
Cancer Control
Cancer Control
Integrated program having an objective of reducing risk, incidence, and mortality from cancer and to enhancing the quality of life for cancer survivors. Realized through an orderly sequence of measures from genetic, epidemiologic, behavioral, social, applied, and surveillance cancer research to the development and implementation of effective interventions, and monitor and analysis of cancer trends in all segments of the population.
C15971
Cancer Control
Cancer Intervention
Health Care Activity
owl:Class
Cancer Control
CL003737
incision of Chest Wall
C0039991
Surgical opening of the mediastinum.
Thoracotomy
Thoracotomy
Incision of Thorax
Procedure_Has_Target_Anatomy only 'Thoracic Cavity'
Thoracotomy
thoracotomy
Therapeutic or Preventive Procedure
C15337
owl:Class
Thoracotomy
Thoracic Surgical Procedure
<def-source>NCI-GLOSS</def-source><def-definition>(thor-a-KAH-toe-mee) An operation to open the chest.</def-definition>
Body Surface Area Calculation Formula
Occupational Activity
Body Surface Area Formula
Body Surface Area Formula
owl:Class
A mathematical formula for calculating the body surface area for an organism.
Body Surface Area Formula
C68645
Body Surface Area Formula
C0489452
Statistical Technique
Surgical removal of part or all of the terminal portion of the ileum.
Resection of Terminal Ileum
Ileectomy
CL354811
Therapeutic or Preventive Procedure
Terminal Ileum Resection
Terminal Ileum Resection
owl:Class
Terminal Ileum Resection
Procedure_Has_Excised_Anatomy only 'Terminal Ileum'
Terminal Ileum Resection
C51610
The procedure in which the exposed pulp is covered with a dressing that protects the pulp and promotes healing and repair.
Direct Pulp Cap
Dental Pulp Capping
Direct Capping
C52574
Direct Pulp Cap
Direct Pulp Capping
Direct Pulp Cap
CL355703
Direct Pulp Cap
Therapeutic or Preventive Procedure
owl:Class
Vapor Phase Cooling
Vapor Phase Cooling
A cryogenic process for the storage and/or shipping of biospecimens. The item to be frozen is placed above a shallow reservoir of cooling liquid in a storage vessel. A vertical temperature gradient is maintained throughout the vapor layer to ensure temperatures sufficiently low to maintain the integrity of the stored material.
CL387507
Freezing
C78211
Vapor Phase Cooling
Activity
Vapor Phase Cooling
Vapor Phase Storage
Vapor-Phase Cooling
owl:Class
Antisense Therapy
Treatment using nucleic acid oligomers to bind to specific mRNA to deter protein production and alter disease process.
Therapeutic or Preventive Procedure
Antisense Oligonucleotide Therapy
Biological Therapy
Antisense Therapy
Antisense Therapy
Antisense Therapy
C16236
CL096839
owl:Class
CDISC SEND Terminology
Schistocyte Count
owl:Class
C74706
Schistocyte Count
CDISC SDTM Terminology
Erythrocyte Count
SCHISTO
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Code
Schistocytes
Schistocyte Count
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
Schistocyte Count
<def-source>CDISC</def-source><def-definition>A measurement of the schistocytes (fragmented red blood cells) in a biological specimen.</def-definition>
The determination of the number of schistocytes present in a sample.
CL384711
CDISC
CL354446
Biopsy of Peritoneum
Procedure_Has_Partially_Excised_Anatomy only Peritoneum
Biopsy of Peritoneum
Peritoneal Biopsy
Removal of tissue from the peritoneum for microscopic examination.
Biopsy
owl:Class
Biopsy of Peritoneum
Diagnostic Procedure
C51627
Biopsy of Peritoneum
C71486
Supportive Care Trial
CL378067
Research Activity
Supportive Care Study
Supportive Care Study
Research Activity
owl:Class
Supportive Care Study
Clinical studies intended to improve the comfort and quality of life for the patient using drugs, nutritional, dietary, behavioral or other interventions.
Supportive Care Study
Extraction
Extraction
Action
Extracted
owl:Class
C61575
The act of pulling out, including the process of obtaining something from a mixture or compound by chemical or physical or mechanical means.
Extraction
Extraction
CL364830
Activity
Extreme Case Sampling
Quantitative Concept
C71508
Extreme Case Sampling
Matched Sampling
Extreme Case Sampling
owl:Class
CL378113
Extreme Case Sampling
ProB-Type Natriuretic Peptide Measurement
ProB-Type Natriuretic Peptide Measurement
ProB-Type Natriuretic Peptide Measurement
C82032
The determination of the amount of proB-type natriuretic peptide present in a sample.
ProB-Type Natriuretic Peptide Measurement
Protein or Enzyme Type Measurement
owl:Class
C15561
Cancer Prevention Intervention
owl:Class
CL030507
Therapeutic or Preventive Procedure
Cancer Prevention
Cancer Prevention Intervention
Cancer Prevention Intervention
Cancer Prevention Intervention
CL336480
owl:Class
Proteomic Profiling
C62669
Proteomic Profiling
Proteomic Profiling
Proteomic Profiling
Laboratory Procedure
Protein Expression Profiling
Molecular Analysis
Ultrasound Imaging
owl:Class
Diagnosis (US)
Diagnostic Ultrasound
Diagnostic Ultrasound
CL003814
Use of ultrasound for imaging or diagnostic purposes. Employs frequencies ranging from 1.6 to 10 megahertz. (DCTD-DIP)
Diagnosis, Ultrasound
C19337
Diagnostic Ultrasound
Diagnostic Ultrasound
Diagnostic Procedure
Biopsy
owl:Class
C51782
Biopsy of Bronchus
Bronchial Biopsy
Removal of tissue from the bronchus for microscopic examination.
Bronchial Biopsy
CL353719
Procedure_Has_Partially_Excised_Anatomy only Bronchus
Diagnostic Procedure
Bronchial Biopsy
Bronchial Biopsy
owl:Class
Personal Behavior
Fasting
Individual Behavior
Fasting
Fasting
Fast
C63663
Fasting
Abstaining from food.
C0015663
Cancer Prevention
CL030891
Ovarian Cancer Prevention
owl:Class
Therapeutic or Preventive Procedure
Prevention of Ovarian Cancer
Prevention of Ovarian Cancer
Prevention of Ovarian Cancer
C15591
Prevention of Ovarian Cancer
Laboratory Procedure
C74903
CDISC SDTM Laboratory Test Terminology by Name
Vitamin C Measurement
CDISC SDTM Terminology
Clinical Data Interchange Standards Consortium Terminology
Vitamin C Measurement
Vitamin C Measurement
The determination of the amount of Vitamin C present in a sample.
CDISC SEND Terminology
<def-definition>A measurement of the Vitamin C in a biological specimen.</def-definition><def-source>CDISC</def-source>
Ascorbic Acid
C0201898
owl:Class
VITC
Vitamin C Measurement
Vitamin C
Vitamin Measurement
CDISC SDTM Laboratory Test Terminology by Code
CL008168
Whole-Genome Shotgun Sequencing
Whole-Genome Shotgun Sequencing
Whole-Genome Shotgun Sequencing
Whole-Genome Shotgun Sequencing
C19653
Shotgun Sequencing
A DNA sequencing method, which involves random sequencing of tiny cloned pieces of the genome, with no foreknowledge of where on a chromosome the piece originally came from. The sequences obtained have a considerable overlap and by using appropriate computer software it is possible to compare sequences and align them to build larger units of genetic information. This sequencing strategy can be automated and leads to rapid sequencing information.
Laboratory Procedure
Molecular Biology Research Technique
owl:Class
FSH
Laboratory Procedure
CDISC SEND Terminology
owl:Class
Hormone Measurement
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Terminology
Follicle Stimulating Hormone Measurement
C74783
Follicle Stimulating Hormone Measurement
Follicle Stimulating Hormone Measurement
CDISC SDTM Laboratory Test Terminology by Code
C0202022
CDISC
Clinical Data Interchange Standards Consortium Terminology
<def-source>CDISC</def-source><def-definition>A measurement of the follicle stimulating hormone (FSH) in a biological specimen.</def-definition>
The determination of the amount of follicle stimulating hormone present in a sample.
Follicle Stimulating Hormone Measurement
Follicle Stimulating Hormone
Allelotype Analysis
owl:Class
CL008922
Allelotyping
Allelotype Analysis
Laboratory Procedure
DNA Analysis
The examination of the extent and variation of allelic loss in polymorphic DNA markers within a sample.
Allelotype Profiling
Allelotype Analysis
Allelotype Analysis
C19823
CL369927
Quantitative Concept
Manhattan Distance
Manhattan Distance Method
Manhattan Distance Metric
Manhattan Distance Method
The sum of the absolute differences between two variables (e.g. |A-B|). Unlike the euclidean distance this does not give an overemphasis to greater distances. This should generally be considered the default distance measure to be used in most operations.
Manhattan Distance Method
C72664
Statistical Technique
owl:Class
Manhattan Distance Method
Immunodiagnostics
owl:Class
Immunodiagnosis
Immunodiagnostic Procedure
C15260
Immunodiagnostic Procedure
Immunodiagnostic Procedure
Immunodiagnostic Procedure
C0021052
Laboratory Procedure
Immunology Test
owl:Class
Statistical Power
Statistical Power
C53191
C0814897
Quantitative Concept
Statistical Technique
Statistical Power
Statistical Power
owl:Class
Cranial Irradiation
CL353848
Cranial Irradiation
Local Therapy
Cranial Irradiation
Cranial Irradiation
Therapeutic or Preventive Procedure
Radiation Therapy
C51988
Diagnostic Endoscopic Surgery
C64992
Endoscopic Surgery
Diagnostic Endoscopic Surgery
Diagnostic Procedure
CL370142
Diagnostic Endoscopic Surgery
Diagnostic Endoscopic Surgery
Diagnostic Surgical Procedure
owl:Class
Transesophageal Echocardiography
A cardiac ultrasound performed by passing a specialized probe containing a transducer into the patient's esophagus.
Transesophageal Echocardiography
Echocardiography
Transesophageal Echocardiography
C80405
Diagnostic Procedure
Transesophageal Echocardiography
owl:Class
Therapeutic or Preventive Procedure
C49133
CL343573
Bilateral Oophorectomy
Surgical removal of both non-diseased ovaries with the goal of preventing ovarian carcinoma.
Bilateral Prophylactic Oophorectomy
Bilateral Prophylactic Oophorectomy
Bilateral Prophylactic Oophorectomy
Bilateral Prophylactic Oophorectomy
owl:Class
Xeroradiography
xeroradiography
Xeroradiography
<def-source>NCI-GLOSS</def-source><def-definition>(ZEE-ro-ray-dee-AH-gra-fee) A type of x-ray in which a picture of the body is recorded on paper rather than on film.</def-definition>
<def-source>MSH2001</def-source><def-definition>A photoelectric method of recording an X-ray image on a coated metal plate, using low-energy photon beams, long exposure time and dry chemical developers.</def-definition>
Diagnostic Procedure
Radiography
Xeroradiography
C17263
C0043350
owl:Class
A printing process of electrostatic electrophotography that uses a photoconductive insulating medium in conjunction with X-rays or gamma rays to produce latent electrostatic-charge patterns for achieving an observable pattern.
Xeroradiography
CTLL-2 Assay
CTLL-2 Assay
C19305
CTLL-2 Assay
A bioassay used in the detection of interleukin-2 (IL-2) or interleukin-4 (IL-4) in the supernatants of in vitro-stimulated cells. It relies on the IL-2- or IL-4-dependence of a cytotoxic cell line (CTLL-2) for in vitro proliferation, and the measurement of the growth of the these cells is usually determined by tritiated-thymidine incorporation pulsed into the CTLL-2 culture 8-12 hours immediately prior to harvesting the CTLL-2 cells.
Laboratory Procedure
Cytotoxic T Lymphocyte Line-2 Assay
owl:Class
IL-2 Assay
CTLL-2 Assay
Cytotoxic T-Lymphocyte Analysis
C0201584
MOP Photochemotherapy
PUVA Photochemotherapy
owl:Class
Therapeutic or Preventive Procedure
MOP Photochemotherapy
CL027221
C16227
MOP Photochemotherapy
MOP Photochemotherapy
Silver
Laboratory Procedure
Silver Staining Method
Silver Staining Method
owl:Class
Silver Staining Method
Silver Staining Method
SILV
C1293950
C23018
Special Histology Staining Method
Silver Staining Method
Silver Staining or GMS staining is a technique for demonstrating fungi in tissue sections. It is primarily based on staining the polysaccharides in fungal cell wall (From BioGenex).
markup
A process for detection and tagging of image features and areas of interest.
Markup
CDISC
Markup
CL366231
Clinical Data Interchange Standards Consortium Glossary Terminology
owl:Class
C63615
Clinical Data Interchange Standards Consortium Terminology
<def-source>CDISC</def-source><def-definition>Computer-processable annotations within a multimedia document. NOTE: In the context of the HL7 specification, markup syntax is according to the XML Specification. [HL7]</def-definition>
Markup
Action
Activity
Markup
Therapeutic or Preventive Procedure
owl:Class
CL031318
C15626
Neuroendocrine Therapy
Neuroendocrine Therapy
Neuroendocrine Therapy
Neuroendocrine Therapy
Endocrine Drug Therapy
Therapeutic or Preventive Procedure
Revision of Ileostomy
C51551
Ileostomy
Revision of Ileostomy
CL356019
Revision of Ileostomy
Revision of a surgical procedure performed to create an opening between the ileum and the outside of the body.
Revision of Ileostomy
owl:Class
Early Detection Study
owl:Class
Early Detection Study
Early Detection Study
Early Detection Study
Research Activity
Clinical studies testing the efficacy of devices, techniques, procedures, or tests for earlier diagnosis of disease.
C71484
Research Activity
Early Detection Trial
CL378108
The act of making something (a product) from raw materials.
FDA
owl:Class
Action
CL333521
MANUFACTURE
Manufacturing
Manufacture
Activity
C43360
Manufacture
Structured Product Labeling Business Operation Terminology
Manufacture
Manufacture
Estrogen Therapy
C15483
Endocrine Drug Therapy
Estrogen Therapy
CL029467
Therapeutic or Preventive Procedure
Estrogen Therapy
owl:Class
Estrogen Therapy
Prior Therapy
owl:Class
Prior Chemotherapy
Clinical Attribute
Prior Chemotherapy Regimens
Prior Chemotherapy
Previous chemotherapy administered as treatment for this cancer.
Prior Chemotherapy
CL014627
Prior Chemotherapy
C16171
Therapeutic or Preventive Procedure
C64895
Genetically Engineered Lymphocyte Therapy
Leukocyte Therapy
CL370173
Genetically Engineered Lymphocyte Therapy
Genetically Engineered Lymphocyte Therapy
owl:Class
Genetically Engineered Lymphocyte Therapy
Cancer Diagnostic or Therapeutic Procedure
C79426
owl:Class
Therapeutic or Preventive Procedure
Intervention or Procedure
Cancer Diagnostic or Therapeutic Procedure
Cancer Diagnostic or Therapeutic Procedure
Cancer Diagnostic or Therapeutic Procedure
owl:Class
Clinical Data Interchange Standards Consortium Terminology
Dohle Body Measurement
Dohle Body Measurement
CDISC SEND Terminology
Laboratory Procedure
Dohle Body Measurement
The determination of the number of Dohle bodies present in a sample.
C74610
<def-definition>A measurement of the Dohle bodies (blue-gray, basophilic, leukocyte inclusions located in the peripheral cytoplasm of neutrophils) in a biological specimen.</def-definition><def-source>CDISC</def-source>
Hematology Test
Dohle Body Measurement
CDISC SDTM Terminology
CL384757
Dohle Bodies
CDISC SDTM Laboratory Test Terminology by Code
DOHLE
CDISC SDTM Laboratory Test Terminology by Name
CDISC
C68775
owl:Class
Irradiate
Treatment with radiation, generally meaning exposure to ionizing radiation or radiation of wavelengths shorter than those of visible light.
C1282930
Irradiation
Radiation Therapy
Irradiation
Irradiation
Irradiation
Activity
C51905
Debridement of Wound of Skin
Debridement
CL353872
Debridement of Wound of Skin
Therapeutic or Preventive Procedure
owl:Class
Debridement of Wound of Skin
Debridement of Wound of Skin
C0003904
Arthroscopy
Arthroscopy
Endoscopic examination of a joint space.
Arthroscopy
owl:Class
Therapeutic or Preventive Procedure
Arthroscopy
Diagnostic Procedure
Procedure_Has_Target_Anatomy only Joint
Endoscopic Procedure
C38033
Hot Flashes Attenuation
CL031780
Hot Flashes Attenuation
Menopausal Symptoms Attenuation
owl:Class
Hot Flashes Attenuation
Hot Flashes Attenuation
Therapeutic or Preventive Procedure
C15672
C53372
Survival Analysis Technique
Survival Analysis Technique
Survival Analysis Technique
Research Activity
owl:Class
CL356549
Statistical Technique
Survival Analysis Technique
Therapeutic Procedure
C38097
Vascular Access Device Placement
Therapeutic or Preventive Procedure
Vascular Access Device Placement
owl:Class
CL322439
Vascular Access Device Placement
Vascular Access Device Placement
Right Colectomy
Right Colectomy
C51623
owl:Class
Right Colectomy
Surgical removal of the right part of the colon.
Right Colectomy
Procedure_Has_Excised_Anatomy only 'Right Colon'
Right Hemicolectomy
Partial Colectomy
CL355468
Therapeutic or Preventive Procedure
Negative-Case Sampling
Negative-Case Sampling
Quantitative Concept
C71511
Negative-Case Sampling
Negative-Case Sampling
Matched Sampling
CL378124
owl:Class
C66959
Triple Blind Study
Triple Blind Study
Research Activity
Triple Blind Study
CL371482
owl:Class
A study in which knowledge of the treatment assignments are concealed from the people who organize and analyze the data of a study as well as from subjects and investigators.
Triple-Blind Study
Triple-Blinded
Triple Blind Study
Trial Blinding Schema
Parotidectomy
Surgery involving complete excision of the parotid gland.
CL353826
Procedure_Has_Completely_Excised_Anatomy only 'Parotid Gland'
Therapeutic or Preventive Procedure
Complete Parotidectomy
Complete Parotidectomy
Complete Parotidectomy
C51491
Complete Parotidectomy
owl:Class
The determination of the amount of macrophage-derived chemokine present in a sample.
Chemokine Measurement
Macrophage-Derived Chemokine Measurement
Macrophage-Derived Chemokine Measurement
C81956
owl:Class
Macrophage-Derived Chemokine Measurement
Macrophage-Derived Chemokine Measurement
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
The determination of the amount of ammonia present in a sample.
Ammonia Measurement
Ammonia, NH3
CDISC SEND Terminology
Ammonia Measurement
C0201879
owl:Class
Laboratory Procedure
Ammonia Measurement
NH3
<def-definition>A measurement of the ammonia in a biological specimen</def-definition><def-source>CDISC</def-source>
C74799
CDISC SDTM Terminology
AMMONIA
CDISC SDTM Laboratory Test Terminology by Name
Chemistry Test
Ammonia Measurement
Ammonia
Cytokeratin-18 Staining Method
Cytokeratin-18 Staining Method
Cytokeratin-18 Staining Method
Special Histology Staining Method
owl:Class
Cytokeratin 18 Staining Method
Laboratory Procedure
Cytokeratin 18
C23027
An immunohistochemical technique to detect cytokeratin 18, an intermediate filament protein, using monoclonal antibody to cytokeratin 18. Specific combinations of cytokeratin peptides are associated with certain epithelial cells, and are therefore useful in the characterization of poorly differentiated carcinoma. The antibody reacts with a large number of epithelial cell types including many ductal and glandular epithelia. The test is used as a clinically significant indicator in distinguishing carcinoma from malignant tumors of non-epithelial origin, such as lymphoma, sarcoma, and melanoma.
Cytokeratin 18 Staining Method
Cytokeratin-18 Staining Method
CK18
C1527158
owl:Class
Inhibin A Measurement
C82020
Protein or Enzyme Type Measurement
Inhibin A Measurement
Inhibin A Measurement
Inhibin A Measurement
The determination of the amount of inhibin A present in a sample.
C74876
Opioid Measurement
Clinical Data Interchange Standards Consortium Terminology
6-Monoacetylmorphine Measurement
6-Monoacetylmorphine Measurement
The determination of the amount of 6-monoacetylmorphine present in a sample.
SIXMAM
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
6-Monoacetylmorphine
6-Monoacetylmorphine Measurement
C1266389
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
Laboratory Procedure
owl:Class
<def-definition>A measurement of the 6-monoacetylmorphine present in a biological specimen.</def-definition><def-source>CDISC</def-source>
6-Monoacetylmorphine Measurement
Rehabilitation
Therapeutic or Preventive Procedure
Rehabilitation
C0034991
rehabilitation therapy
C15315
Restoration of the ability to function in a normal or near normal manner following disease, illness, or injury.
Rehabilitation
Rehabilitation
Rehabilitation, Medical
Physical Health Services / Rehabilitation
Supportive Care
owl:Class
owl:Class
Therapeutic or Preventive Procedure
Amputation
Amputation
The surgical removal of all or part of a limb or other appendage.
C15179
Amputation
Severed Digit(s), (finger or toe)
<def-source>NCI-GLOSS</def-source><def-definition>(am-pyoo-TAY-shun) Surgery to remove part or all of a limb or appendage.</def-definition>
amputation
C0002688
Amputation
Surgical Procedure by Method
Toe or finger, severed
CL356941
Dynamic Optical Breast Imaging
Dynamic Optical Breast Imaging Scan
Breast Imaging Study
owl:Class
Dynamic Optical Breast Imaging
Dynamic Optical Breast Imaging
C53402
Dynamic Optical Breast Imaging
Diagnostic Procedure
A scan using red light instead of x-rays to differentiate between benign and malignant conditions. It measures physiological changes in the breast when the breast is gently squeezed by an air filled bag. It is relatively comfortable (compared to a mammogram).
DOBI
Drug Development, Experimental
Drug Development, Experimental
C15982
owl:Class
Drug Development, Experimental
Drug Development, Experimental
Drug Development
Research Activity
Drug Testing/Development, Experimental
CL003852
CL008938
A method for rapidly obtaining near-pure aggregates of epithelial cell populations. Smears are prepared, rapidly fixed in methanol and stained. Microscopic examination permits precise identification of epithelial cell aggregates for separation by laser capture microdissection.
Cytological Procedure
Laboratory Procedure
Epithelial Cell Aggregation and Separation
EASI
Epithelial Cell Aggregation and Separation
Epithelial Cell Aggregation and Separation
owl:Class
Epithelial Cell Aggregation and Separation
C19825
Validation of Technology
Validation
C15875
CL001078
Validation of Technology
Occupational Activity
Validation of Technology
Validation of Technology
owl:Class
Surgical removal and examination of the sentinel node, the lymph node which is first in receiving the lymphatic drainage of a specified anatomic location and is most likely to be affected by the lymphatic spread of cancer.
sentinel lymph node biopsy
Sentinel Node Biopsy
Sentinel Lymph Node Biopsy
Sentinel Lymph Node Biopsy
<def-source>NCI-GLOSS</def-source><def-definition>Removal and examination of the sentinel node(s) (the first lymph node(s) to which cancer cells are likely to spread from a primary tumor). To identify the sentinel lymph node(s), the surgeon injects a radioactive substance, blue dye, or both near the tumor. The surgeon then uses a scanner to find the sentinel lymph node(s) containing the radioactive substance or looks for the lymph node(s) stained with dye. The surgeon then removes the sentinel node(s) to check for the presence of cancer cells.</def-definition>
SNB
C0796693
Sentinel Lymph Node Biopsy
C15667
Sentinel Lymph Node Biopsy
owl:Class
Diagnostic Procedure
Lymph Node Biopsy
Interpolation Imputation Technique
Interpolation Imputation Technique
Quantitative Concept
C81208
Statistical Imputation
Interpolation Imputation Technique
Interpolation Imputation Technique
owl:Class
The substitution of missing data with an estimated value that falls between known data points.
Cross-Sectional Study
C0010362
owl:Class
Cross-Sectional Study
Cross-Sectional Study
Cross-Sectional Study
Research Activity
Study Design
C53310
owl:Class
C15644
C0398523
Bone Marrow Aspiration
<def-source>NCI-GLOSS</def-source><def-definition>(as-per-AY-shun) The removal of a small sample of bone marrow (usually from the hip) through a needle for examination under a microscope.</def-definition>
Diagnostic Procedure
Diagnostic Aspiration
bone marrow aspiration
Bone Marrow Aspiration
Bone Marrow Aspiration
Bone Marrow Aspiration
Aspiration of immature hematopoietic elements and blood from the bone marrow. It is done for the evaluation of hematopoietic disorders and for the evaluation of infectious diseases and cytogenetic studies.
A procedure performed to replace a narrowed and calcified aortic valve in patients unable to withstand open chest surgery. A bioprosthesis is advanced through the vessels with a catheter up to the diseased native aortic valve. Once the catheter is positioned in the opening of the aortic valve it releases the bioprosthesis at the mid part of the aortic valve.
Percutaneous Aortic Valve Replacement
Percutaneous Aortic Valve Replacement
Aortic Valve Replacement
owl:Class
Percutaneous Aortic Valve Replacement
C80448
Therapeutic or Preventive Procedure
Percutaneous Aortic Valve Replacement
owl:Class
Colostomy
Colostomy
The surgical creation of an opening between the colon and the surface of the body. (MeSH)
<def-source>NCI-GLOSS</def-source><def-definition>(ko-LAHS-toe-mee) An opening into the colon from the outside of the body. A colostomy provides a new path for waste material to leave the body after part of the colon has been removed.</def-definition>
C0009410
Therapeutic or Preventive Procedure
colostomy
Colostomy
C15211
Colon and Rectal Surgery
Colostomy
Procedure_Has_Target_Anatomy some Colon
Community Practice
CL003242
Community Practice
Community Practice
Healthcare services rendered within a given population or segment of a society.
Community Practice
C15937
owl:Class
Health Care Activity
Community Health Service
Attachment
CL364827
Attachment
The act of affixing one thing to another.
owl:Class
Action
C61470
Attachment
Activity
Attachment
owl:Class
Surgery to remove part of each of the fallopian tubes.
Bilateral Partial Salpingectomy
CL354984
Partial Salpingectomy
Procedure_Has_Partially_Excised_Anatomy only 'Left Fallopian Tube'
Bilateral Salpingectomy
C51668
Bilateral Partial Salpingectomy
Bilateral Partial Salpingectomy
Procedure_Has_Partially_Excised_Anatomy only 'Right Fallopian Tube'
Therapeutic or Preventive Procedure
Bilateral Partial Salpingectomy
Thyroid Antithyroglobulin Antibody Measurement
Thyroid Antithyroglobulin Antibody Measurement
owl:Class
C81992
Immunology Test
Thyroid Antithyroglobulin Antibody Measurement
Thyroid Antithyroglobulin Antibody Measurement
The determination of the amount of thyroid antithyroglobulin antibodies present in a sample.
Removal of tissue from the vagina for microscopic examination.
Vaginal Biopsy
Vaginal Biopsy
Diagnostic Procedure
owl:Class
Procedure_Has_Partially_Excised_Anatomy only Vagina
Biopsy
Vaginal Biopsy
Vaginal Biopsy
CL356131
C51595
Maximum Heart Rate
CDISC SDTM Terminology
Quantitative Concept
Maximum Heart Rate
The minimum time between successive cycles of contraction and subsequent relaxation of the heart, usually expressed as beats per minute, obtained from a set of measurements of the heart rate.
CDISC
<def-source>CDISC</def-source><def-definition>The minimum time between successive cycles of contraction and subsequent relaxation of the heart, usually expressed as beats per minute, obtained from a set of measurements of the heart rate. (NCI)</def-definition>
CDISC SDTM ECG Test Name Terminology
C0744679
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM ECG Test Terminology by Code
owl:Class
HRMAX
Heart Rate
Summary (Max) Heart Rate
Maximum Heart Rate
C39779
Maximum Heart Rate
HR-max
Sputum Cytology
CL016115
Sputum Cytology
Sputum Cytology Screening
Sputum Cytology
Sputum Cytology
Cytologic Test
A diagnostic technique for lung cancer detection. Looks for abnormal cell cytology in sputum.
Laboratory Procedure
owl:Class
C16192
Diagnostic Procedure
Immunology Test
C71329
Laboratory Procedure
HLA Testing
C0242318
A process in which blood or tissue samples are analyzed to determine their human leukocyte antigen (HLA) profiles.
HLA Typing
HLA Typing
HLA Typing
owl:Class
HLA Typing
TIL Research
Basic Cancer Research
TIL Research
owl:Class
C15962
TIL Research
Research on tumor-infiltrating lymphocytes and their use as a cancer treatment.
TIL Research
CL003604
Research Activity
Fluorophotometry
C0016353
Measurement of light given off by fluorescein in order to assess the integrity of various ocular barriers. The method is used to investigate the blood-aqueous barrier, blood-retinal barrier, aqueous flow measurements, corneal endothelial permeability, and tear flow dynamics (From MSH2001).
Fluorophotometry
Diagnostic Procedure
owl:Class
Fluorophotometry
C16587
Diagnostic Procedure
Fluorophotometry
C51910
Superficial Parotidectomy
CL356076
Surgery involving excision of the superficial portion of the parotid gland.
Partial Parotidectomy
Superficial Parotidectomy
owl:Class
Superficial Parotidectomy
Therapeutic or Preventive Procedure
Superficial Parotidectomy
Hematology Test
Sheep Red Blood Cell Rosetting
A technique for identifying and removing T lymphocytes based on their ability to form rosettes with untreated sheep erythrocytes.
Sheep Red Blood Cell Rosetting
Sheep Red Blood Cell Rosetting
C72897
CL383356
Laboratory Procedure
Sheep Red Blood Cell Rosetting
owl:Class
C50428
FDA
Dose
Functional Concept
Underdose
Patient Problem Codes FDA CDRH
Underdose
Underdose
Underdose
owl:Class
CL354861
Aldolase Measurement
Protein or Enzyme Type Measurement
Aldolase Measurement
Laboratory Procedure
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
Aldolase
The determination of the amount of aldolase present in a sample.
Aldolase Measurement
Aldolase Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the aldolase enzyme in a biological specimen.</def-definition>
C0201839
ALDOLASE
owl:Class
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Name
C74731
CDISC SEND Terminology
CDISC
Direct Laryngoscopy with Biopsy
owl:Class
C51659
Direct Laryngoscopy with Biopsy
CL354493
Direct Laryngoscopy with Biopsy
Removal of laryngeal tissue under direct visualization for microscopic examination.
Diagnostic Procedure
Procedure_Has_Partially_Excised_Anatomy only Larynx
Biopsy
Direct Laryngoscopy with Biopsy
DNA Stability Analysis
DNA Stability Analysis
Laboratory Procedure
C63329
DNA Stability Analysis
DNA Stability Analysis
CL365248
Molecular Analysis
owl:Class
owl:Class
Nutrition Research, Basic Non-Clinical Trials
Research Activity
Nutrition Research, Basic Non-Clinical Trials
CL000602
Nutrition Research, Basic Non-Clinical Trials
Basic Science Research
C15823
Nutrition Research, Basic Non-Clinical Trials
C15570
CL030647
Pressor Support
Therapeutic or Preventive Procedure
owl:Class
Pressor Support
Supportive Care
Pressor Support
Pressor Support
Targeted Protein Toxin Therapy
Targeted Protein Toxin Therapy
Therapeutic or Preventive Procedure
C64864
CL370549
owl:Class
Targeted Protein Toxin Therapy
Biological Therapy
Targeted Protein Toxin Therapy
owl:Class
Removal of tissue from the salivary gland for microscopic examination.
Biopsy of Salivary Gland
CL354448
Biopsy
C51488
Biopsy of Salivary Gland
Biopsy of Salivary Gland
Diagnostic Procedure
Biopsy of Salivary Gland
Procedure_Has_Partially_Excised_Anatomy only 'Salivary Gland'
Oophorectomy
Partial or complete removal of one or both of the ovaries.
Oophorectomy
Ovariectomy
C0029936
owl:Class
Gynecological Surgical Procedure
<def-source>NCI-GLOSS</def-source><def-definition>(o-o-for-EK-toe-mee) Surgery to remove one or both ovaries.</def-definition>
Oophorectomy
Surgical Castration
Female Castration
Ovarian Ablation
Oophorectomy
Procedure_Has_Excised_Anatomy only Ovary
Therapeutic or Preventive Procedure
C15291
oophorectomy
CDISC SDTM Terminology
C0202001
Erythropoietin Measurement
Erythropoietin Measurement
The determination of the amount of erythropoietin hormone present in a sample.
owl:Class
EPO
Hormone Measurement
C74855
Erythropoietin Measurement
CDISC SDTM Laboratory Test Terminology by Code
<def-definition>A measurement of the erythropoietin hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Name
Erythropoietin Measurement
Erythropoietin
Laboratory Procedure
Hematopoietin
Clinical Data Interchange Standards Consortium Terminology
owl:Class
Inguinal Orchiectomy
Procedure_Has_Target_Anatomy only 'Inguinal Region'
C0747053
Therapeutic or Preventive Procedure
Inguinal Orchiectomy
Inguinal Orchiectomy
inguinal orchiectomy
Surgical removal of a testis through an inguinal approach.
<def-source>NCI-GLOSS</def-source><def-definition>(IN-gwin-al or-kee-EK-toe-mee) An operation in which the testicle is removed through an incision in the groin.</def-definition>
Inguinal Orchiectomy
C15724
Orchiectomy
Procedure_Has_Completely_Excised_Anatomy only Testis
C67359
Therapeutic or Preventive Procedure
End-of-Life Treatment Management
End-of-Life Treatment Management
End-of-Life Treatment Management
owl:Class
Supportive Care
End-of-Life Treatment Management
CL371747
C38067
Therapeutic Procedure
Incision and Drainage
Incision &amp; Drainage
owl:Class
C0152277
Incision and Drainage
Incision and Drainage
Incision and Drainage
Therapeutic or Preventive Procedure
owl:Class
C15352
islets of Langerhans transplantation
<def-source>MSH2001</def-source><def-definition>The transference of pancreatic islets within an individual, between individuals of the same species, or between individuals of different species.</def-definition>
Pancreatic Islet Transplantation
C0079646
Pancreatic Islet Transplantation
Therapeutic or Preventive Procedure
Organ Transplantation
Pancreatic Islet Transplantation
Pancreatic Islet Transplantation
The separation of specific cells or cell populations from a heterogeneous mixture. Specifically it refers to the selective removal of a population of undesired cells through recognition and elimination of cells bearing the specified characteristics.
Negative Selection
C70599
Mixed Category Laboratory Procedure
CL376013
Negative Selection
Negative Selection
owl:Class
Negative Selection
Laboratory Procedure
Child Development Study
Research Activity
Child Development Study
Child Development Study
C15202
CL355027
Child Health Study
owl:Class
Child Development Study
Conventional Surgery
Conventional Surgery
owl:Class
Surgery using a scalpel. As opposed to laser surgery, cryosurgery, etc
C1521745
Surgical Procedure by Method
Therapeutic or Preventive Procedure
Conventional Surgery
Conventional Surgery
C16079
Surgery, Digestive System
Surgical Procedure by Site or System
Digestive System Surgery
owl:Class
Digestive System Surgery
Surgery performed on any part of the digestive system.
Digestive System Surgery
digestive system surgical procedure
operative procedure on the gastrointestinal system
C15330
Digestive System Surgery
Therapeutic or Preventive Procedure
C0038898
Procedure_Has_Target_Anatomy only 'Gastrointestinal System'
gastrointestinal system operative procedure
digestive system operative procedure
Surgery, Gastrointestinal
<def-source>MSH2001</def-source><def-definition>Surgery performed on the digestive system or its parts.</def-definition>
gastrointestinal surgical procedure
operative procedure on the digestive system
C0500222
Cellular Therapy
owl:Class
C70601
Cellular Therapy
Cellular Therapy
Therapeutic or Preventive Procedure
Cellular Therapy
Therapeutic Procedure
Utilization of specific cells modified or not for treatment of diseases. Donor lymphocyte infusion is a type of cellular therapy.
Castration
Surgical Castration
Procedure_Has_Excised_Anatomy only Gonad
Surgical Castration
Surgical Castration
Surgical removal of the ovaries or testes.
castration
C0007344
Ablative Endocrine Surgery
<def-source>NCI-GLOSS</def-source><def-definition>Removal or destruction of the testicles or ovaries using radiation, surgery, or drugs. Medical castration refers to the use of drugs to suppress the function of the ovaries or testicles.</def-definition>
C15198
surgical castration
<def-source>NCI-GLOSS</def-source><def-definition>Surgical removal of the testicles (orchiectomy) or ovaries (oophorectomy) to stop the production of sex hormones. Decreasing the levels of hormones may stop the growth of certain cancers.</def-definition>
<def-source>MSH2001</def-source><def-definition>Surgical removal or artificial destruction of gonads.</def-definition>
Surgical Castration
Therapeutic or Preventive Procedure
Urogenital Surgical Procedure
owl:Class
CDISC SDTM Action Taken with Study Treatment Terminology
CDISC SDTM Terminology
CL354505
DRUG WITHDRAWN
Activity
Clinical Data Interchange Standards Consortium Terminology
An indication that a medication schedule was modified through termination of a prescribed regimen of medication.
owl:Class
CDISC
<def-source>CDISC</def-source><def-definition>An indication that a medication schedule was modified through termination of a prescribed regimen of medication. (NCI)</def-definition>
Drug Withdrawn
Drug Withdrawn
Drug Withdrawn
Drug Withdrawn
C49502
Action Taken with Study Treatment
Thyroid Antimicrosomal Antibody Measurement
The determination of the amount of thyroid antimicrosomal antibodies present in a sample.
Thyroid Antimicrosomal Antibody Measurement
owl:Class
Thyroid Antimicrosomal Antibody Measurement
C81991
Immunology Test
Thyroid Antimicrosomal Antibody Measurement
Family Study
Family Study
Family Study
Family Study
owl:Class
Population Study
C0199236
C15407
Research Activity
Focused Ultrasound Therapy
Focused Ultrasound Therapy
Focused Ultrasound Therapy
Therapy (Focused US)
C15979
Focused Ultrasound Therapy
Therapy, Focused Ultrasound
owl:Class
Therapeutic or Preventive Procedure
Thermal Ablation Therapy
High Power Focused Ultrasound
Focused Ultrasound
CL003815
Minimally invasive procedure for ablating tumors. The primary mechanism of tissue damage is thermal.
Research Activity
Stem Cell Research
Stem Cell Research
Biomedical Occupation or Discipline
C16200
Stem Cell Research
owl:Class
CL024201
Stem Cell Research
Nutrition, Fats, Saturated
Nutrition, Fats, Saturated
owl:Class
Nutrition, Fats, Saturated
Nutrition, Fats
Role of saturated fats in cancer causation or prevention and in general health.
C15825
CL000605
Lipid Nutrition, Saturated
Nutrition, Fats, Saturated
Research Activity
CDISC SEND Terminology
Laboratory Procedure
Blood Cell Count Ratio Measurement
CDISC SDTM Laboratory Test Terminology by Code
Reactive Lymphocyte to Lymphocyte Ratio Measurement
CDISC SDTM Terminology
CL384345
CDISC
<def-definition>A relative measurement (ratio or percentage) of the reactive lymphocytes (lymphocytes which have become large due to an antigen reaction) to all lymphocytes in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Laboratory Test Terminology by Name
C74654
Reactive Lymphocytes/Lymphocytes
LYMRCTLY
Clinical Data Interchange Standards Consortium Terminology
Reactive Lymphocyte to Lymphocyte Ratio Measurement
The determination of the ratio of reactive lymphocytes compared to all lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
owl:Class
Reactive Lymphocyte to Lymphocyte Ratio Measurement
Reactive Lymphocyte to Lymphocyte Ratio Measurement
C16141
Pain Research
Research Activity
Pain Research
Research Activity
CL014173
Pain Research
owl:Class
Research as to the cause of pain and the treatment thereof
Pain Research
Challenge to research community to revolutionize the classification of human tumors, away from classification based on morphology, toward a more clinically predictive and useful classification system based on molecular characterization of tumors. (Bypass Budget)
Director's Challenge
C16090
Molecular Classification of Tumors
Molecular Fingerprinting Initiative
Molecular Classification of Tumors
Molecular Profiling Initiative
Intellectual Product
CL008665
Extraordinary Opportunities: the Director's Challenge: Toward a Molecular Classification of Tumors
Molecular Classification of Tumors
Director's Challenge: Towards a Molecular Classification of Tumors
Molecular Classification of Tumors
owl:Class
Extraordinary Opportunity: Defining the Signatures of Cancer Cells: Detection and Diagnosis
Extraordinary Opportunities for Investment
Releasing Hormone Agonist Therapy
C15489
Releasing Hormone Agonist Therapy
CL029587
Therapeutic or Preventive Procedure
owl:Class
Releasing Hormone Agonist Therapy
Releasing Factor Agonist Therapy
Endocrine Drug Therapy
Releasing Hormone Agonist Therapy
CL378319
Balloon Brachytherapy
Therapeutic or Preventive Procedure
Intracavitary Balloon Brachytherapy
Intracavitary Radiation Therapy
Intracavitary Balloon Brachytherapy
owl:Class
Intracavitary Balloon Brachytherapy
C71736
Intracavitary Balloon Brachytherapy
Activity
The final result of a determination of the value, significance, or extent of.
Assess
Assessment
Assessment
Assessment
Assessed
C1516048
Action
owl:Class
C25217
Intellectual Product
Assessment
Laboratory Procedure
Serotonin Measurement
owl:Class
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Terminology
CDISC SEND Terminology
Hormone Measurement
<def-definition>A measurement of the serotonin hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
Serotonin Measurement
SRTONIN
Serotonin Measurement
C0202217
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Laboratory Test Terminology by Code
Serotonin Measurement
C74872
The determination of the amount of serotonin hormone present in a sample.
Serotonin
Community Clinical Oncology Program
Community Oncology
Health Care Activity
CL008689
Cancer Research
owl:Class
Community Clinical Oncology Program
C16097
Community Clinical Oncology Program
The Community Clinical Oncology Program (CCOP) was established by the National Cancer Institute (NCI) in 1983. Through this program, community physicians work with scientists conducting NCI-supported clinical trials.
CCOP
Oncology Programs
Community Clinical Oncology Program
Cytogenetic Analysis
Chromosome 5q31-33 Deletion Measurement
Chromosome 5q31-33 Deletion Measurement
C79613
owl:Class
Laboratory Procedure
Chromosome 5q31-33 Deletion Measurement
Chromosome 5q31-33 Deletion Measurement
C0014392
Therapeutic or Preventive Procedure
Enucleation
Enucleation
Excision
A surgical procedure by which tissue or an organ (usually containing a tumor) is removed without rupture from a specific anatomic site.
Enucleation
Enucleation
C48601
owl:Class
owl:Class
Clinical Trials Design
CL378264
A portion of a study containing one or more study segments with a consistent objective such as screening subjects or treating disease.
Clinical Trial Epoch
Clinical Trial Epoch
Research Activity
Clinical Trial Epoch
Epoch
C71738
Clinical Trial Epoch
CL031799
C15676
Androgen Suppression
Androgen Suppression
androgen suppression
Endocrine Drug Therapy
Androgen Suppression
Therapeutic or Preventive Procedure
<def-source>NCI-GLOSS</def-source><def-definition>Treatment to suppress or block the production of male hormones. Androgen suppression is achieved by surgical removal of the testicles, by taking female sex hormones, or by taking other drugs, antiandrogens. Also called androgen ablation.</def-definition>
Androgen Ablation
owl:Class
Blockage of the production of male hormones.
Androgen Suppression
C71137
CL377575
Functional Concept
A treatment plan that specifies the amount, schedule, and the duration of intervention(s).
Dose Regimen
Dose Regimen
DOSRGM
owl:Class
CDISC Observation Class Terminology
Dose Regimen
Treatment Regimen
Dose Regimen
CDISC SDTM Terminology
Antinuclear Antibody Measurement
CDISC SDTM Laboratory Test Terminology by Name
Clinical Data Interchange Standards Consortium Terminology
CDISC SEND Terminology
<def-source>CDISC</def-source><def-definition>A measurement of the antinuclear antibodies (antibodies that attack the body's own tissue) in a biological specimen.</def-definition>
Laboratory Procedure
Immunology Test
Antinuclear Antibody Measurement
Antinuclear Antibody Measurement
CDISC SDTM Laboratory Test Terminology by Code
C0702121
The determination of the amount of antinuclear antibodies present in a sample.
ANA
owl:Class
Antinuclear Antibody Measurement
C74916
CDISC
Antinuclear Antibodies
Supportive Care
CL032252
C15740
Menopausal Symptoms Attenuation
Menopausal Symptoms Attenuation
Menopausal Symptoms Attenuation
Therapy to reduce the effects of menopausal symptoms. May also be necessary in order to counteract the effect of various chemotherapy treatments.
Therapeutic or Preventive Procedure
Menopausal Symptoms Attenuation
owl:Class
Fibroblast Growth Factor Basic Form Measurement
C82014
owl:Class
Fibroblast Growth Factor Basic Form Measurement
Protein or Enzyme Type Measurement
Fibroblast Growth Factor Basic Form Measurement
Fibroblast Growth Factor Basic Form Measurement
The determination of the amount of fibroblast growth factor basic form present in a sample.
Energy Therapy
Therapeutic or Preventive Procedure
Electromagnetic-Based Therapy
CL024616
Bioelectro-Magnetics
Electromagnetic-Based Therapy
The unconventional use of electromagnetic fields for medical or therapeutic purposes.
owl:Class
Bioelectromagnetics
Bioelectromagnetic Therapies
Electromagnetic-Based Therapy
C16207
Bioelectromagnetic-Based Therapy
Electromagnetic-Based Therapy
PSA Velocity
CL017743
A type of PSA assay which compares changes in PSA levels over time. A sharp rise in the PSA level raises the suspicion of cancer. (from Cancer Information Service)
PSA Velocity
C20119
Prostate Specific Antigen Velocity
Quantitative Concept
owl:Class
Prostate Specific Antigen Measurement
PSA Velocity
PSA Velocity
C82045
Segmented Neutrophil to Leukocyte Ratio Measurement
The determination of the ratio of segmented neutrophils compared to leukocytes present in a sample. The measurement may be expressed as a ratio or percentage.
Blood Cell Count Ratio Measurement
Segmented Neutrophil to Leukocyte Ratio Measurement
Laboratory Procedure
owl:Class
Segmented Neutrophil to Leukocyte Ratio Measurement
Segmented Neutrophil to Leukocyte Ratio Measurement
Forced Expiratory Volume 1 Test
C38084
Diagnostic Procedure
Forced Expiratory Volume in 1 Second
FEV1%VC
PFT/FEV1
A test of lung function, the FEV1 is the volume exhaled during the first second of a forced expiratory maneuver started from the level of total lung capacity. It is the most frequently used index for assessing bronchoconstriction or bronchodilatation.
FEV1
Pulmonary Function Test
Pulmonary Function Test/Forced Expiratory Volume 1
Forced Expiratory Volume in 1 Second
owl:Class
Forced Expiratory Volume in 1 Second
Forced Expiratory Volume in 1 Second
CL322432
Protein or Enzyme Type Measurement
Plasminogen Activator Inhibitor-1 Measurement
C82030
Plasminogen Activator Inhibitor-1 Measurement
Plasminogen Activator Inhibitor-1 Measurement
The determination of the amount of plasminogen activator inhibitor-1 present in a sample.
Plasminogen Activator Inhibitor-1 Measurement
owl:Class
Diagnostic Procedure
Breast Cancer Diagnostic Procedure
Breast Cancer Diagnostic Procedure
Cancer Diagnostic Procedure
owl:Class
Breast Cancer Diagnostic Procedure
C79430
Breast Cancer Diagnostic Procedure
Breast Cancer Diagnostic or Therapeutic Procedure
CL384431
CDISC
Unclassified Crystal Measurement
C74757
CDISC SDTM Laboratory Test Terminology by Code
Crystal Growth Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the unclassifiable crystals present in a urine specimen.</def-definition>
owl:Class
CDISC SDTM Terminology
The determination of the amount of unclassified crystals present in a urine sample.
CDISC SDTM Laboratory Test Terminology by Name
Unclassified Crystal Measurement
Urine Chemistry Measurement
Unclassified Crystal Measurement
CYUNCLA
Unclassified Crystals
Clinical Data Interchange Standards Consortium Terminology
CDISC SEND Terminology
Unclassified Crystal Measurement
Laboratory Procedure
Transplantation
C15431
Therapeutic or Preventive Procedure
Stem Cell Transplantation
Hematopoietic Stem Cell Transplantation
Hematopoietic Stem Cell Transplantation
Hematopoietic Stem Cell Transplantation
A method of replacing the immature blood-forming cells lost due to high-dose chemotherapy, and possibly radiation therapy, used to destroy leukemia cells. The stem cells are given to the patient after treatment to help the bone marrow recover and continue producing healthy blood cells.
Hematopoietic Stem Cell Transplantation
C0242603
owl:Class
stem cell transplantation
Run-On Assays
CL005598
A method to determine the constellation of sequences being actively transcribed at a given moment. Cell nuclei are harvested, and then supplied with a pulse of radioactive nucleotides. Transcription is allowed to proceed to an end, but additional initiations are inhibited. RNAs are then extracted and separated by gel electrophoresis.
Run-On Assays
C19582
Run-On Assays
owl:Class
Laboratory Procedure
RNA Analysis
Run-On Assays
An ultrasound of cardiac activity during or immediately following stress or exercise.
Stress Echocardiography
Stress Echocardiography
C80407
owl:Class
Stress Echo
Stress Echocardiography
Echocardiography
Stress Echocardiography
Diagnostic Procedure
Bi-variate Normal Distribution
Bivariate Normal Distribution
CL356393
Bivariate Normal Distribution
Quantitative Concept
C53217
Bivariate Normal Distribution
A normal distribution which models two variables of interest. The parameters of the bivariate normal distribution include the mean and variance of each individual variable and the correlations between variables.
Normal Distribution
owl:Class
Bivariate Normal Distribution
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Terminology
C1266501
CDISC SDTM Laboratory Test Terminology by Name
C74878
Dihydrocodeine
Dihydrocodeine Measurement
Dihydrocodeine Measurement
Dihydrocodeine Measurement
DIHYDCDN
CDISC SEND Terminology
<def-definition>A measurement of the dihydrocodeine present in a biological specimen.</def-definition><def-source>CDISC</def-source>
Laboratory Procedure
owl:Class
Dihydrocodeine Measurement
The determination of the amount of dihydrocodeine present in a sample.
Opioid Measurement
Therapeutic or Preventive Procedure
Smoking Prevention
Preventive Intervention
owl:Class
CL008833
Smoking Prevention
C16114
Smoking Prevention
Smoking Prevention
Laboratory Procedure
Mescaline Measurement
C75355
C1266590
Mescaline Measurement
Mescaline Measurement
owl:Class
The determination of the amount of cocaine present in a sample.
Hallucinogen Measurement
Mescaline Measurement
White Blood Cell Cast Measurement
Clinical Data Interchange Standards Consortium Terminology
CSWBC
<def-source>CDISC</def-source><def-definition>A measurement of the white blood cell casts present in a urine specimen.</def-definition>
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
CDISC
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Name
White Blood Cell Cast Measurement
Urine Sediment Analysis Measurement
WBC Casts
CL384446
White Blood Cell Cast Measurement
Laboratory Procedure
owl:Class
White Blood Cell Cast Measurement
The determination of the number of white blood cell casts present in a sample.
C74778
A procedure, also known as sonohysterography or saline infusion sonography, using a minimally invasive ultrasound technique to view the inside of the uterus. Sterile saline is injected into the endometrial cavity thereby distending the endometrial cavity, providing good visualization of the anatomic structures within.
Saline Infusion Sonography
Diagnostic Procedure
Hysterosonography
C38066
Hysterosonography
Hysterosonography
owl:Class
Ultrasound Imaging
CL322419
Hysterosonography
Sonohysterography
CL370579
Indirect Bilirubin Measurement
Liver Function Test
Indirect Bilirubin Measurement
Laboratory Procedure
Indirect Bilirubin Measurement
Bilirubin is in the insoluble form, unconjugated bilirubin (indirect bilirubin).The non-water soluble, free bilirubin does not react with sulfanilic acid at acidic pH to produce a red colored complex until an accelearator, alcohol, is added to the solution to perform a quantitative measurement of unconjugated bilirubin levels.
CDISC SDTM Laboratory Test Terminology by Name
<def-source>CDISC</def-source><def-definition>A measurement of the unconjugated or non-water-soluble bilirubin in a biological specimen.</def-definition>
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
Indirect Bilirubin Measurement
BILIND
owl:Class
CDISC SDTM Terminology
C64483
Indirect Bilirubin
CDISC
Interleukin 33 Measurement
CL384312
Interleukin 33
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Code
INTLK33
Interleukin 33 Measurement
Laboratory Procedure
Cytokine Measurement
CDISC SDTM Laboratory Test Terminology by Name
C74831
owl:Class
<def-definition>A measurement of the interleukin 33 in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Terminology
Interleukin 33 Measurement
The determination of the amount of interleukin 33 present in a sample.
CDISC SEND Terminology
Interleukin 33 Measurement
Challenge
owl:Class
Challenge
C0805586
Challenge
Action
C78166
The administration of a substance in order to assess for a response.
Activity
Challenge
Circular dichroism (CD), optical rotatory dispersion (ORD). Linearly polarized light can be thought of as a combination of right and left-handed circularly polarized light of equal phase and amplitude. ORD is the phenomenon observed when a substance exhibits a difference in the index of refraction of the right vs. left circularly polarized components, resulting in a change in the plane of polarization. When an optically active substance contains a chromophore that absorbs in the optically active region of the spectrum, CD is observed, which involves the preferential absorbance of right or left-handed circular polarized light. Both ORD and CD depend on the wavelength of the radiation and the structure of the molecule. Structural elements of proteins that exhibit differences in CD/ORD include the alpha helix, the beta sheet, and random coil segments.
Spectroscopy
Research Activity
Spectroscopy, CD/ORD
owl:Class
Spectroscopy, Circular Dichroism
C19041
CL000929
Spectroscopy, Circular Dichroism
Spectroscopy, Circular Dichroism
Spectroscopy, Circular Dichroism
Vaccine Clinical Trial
C15864
owl:Class
Vaccine Clinical Trial
Clinical Trial
Vaccine Clinical Trial
Vaccine Clinical Trial
CL001064
Research Activity
owl:Class
Urea Measurement
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Code
Laboratory Procedure
<def-source>CDISC</def-source><def-definition>A measurement of the urea nitrogen in a blood specimen.</def-definition>
C0005845
Blood Urea Nitrogen Measurement
Blood Urea Nitrogen
CDISC
Clinical Data Interchange Standards Consortium Terminology
Blood Urea Nitrogen Measurement
Blood Urea Nitrogen Measurement
C61019
BUN
Blood Urea Nitrogen Measurement
CDISC SDTM Laboratory Test Terminology by Name
A quantitative measurement of the amount of urea nitrogen present in a serum sample.
CDISC SDTM Terminology
Clinical or Research Activity
Clinical or Research Activity
CL024545
owl:Class
Activity
Any specific activity undertaken during the course of a clinical study or research protocol.
Clinical or Research Activity
Activity
C16203
Clinical or Research Activity
Heart Valve Repair
Mitral Valve Repair
Mitral Valve Repair
Mitral Valve Repair
C80449
Surgery performed for the purpose of repairing stenosis or regurgitation of the mitral valve.
Therapeutic or Preventive Procedure
owl:Class
Mitral Valve Repair
CDISC SDTM Terminology
OPIATE
CDISC
The determination of the amount of opiates present in a sample.
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
The determination of the amount of any opiate present in a sample.
C0242401
C74796
Laboratory Procedure
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Code
<def-source>CDISC</def-source><def-definition>A measurement of any opiate class drug present in a biological specimen.</def-definition>
Opioid Measurement
Opiate Measurement
owl:Class
Opiate Measurement
Opiate Measurement
Opiate
Opiate Measurement
Preventive Intervention
Improve understanding of the biology of opportunistic pathogens, identify potential molecular targets for effective therapies, and discover and delineate the structure and function of potential agents for prevention and treatment of HIV-associated OIs and other infections that are modified by HIV infection.
Prevention and Treatment of Opportunistic Infection
owl:Class
Prevention and Treatment of Opportunistic Infection
Therapeutic or Preventive Procedure
Prevention and Treatment of Opportunistic Infection
C15840
Improve understanding of the biology of opportunistic pathogens, identify potential molecular targets for effective therapies, and discover and delineate the structure and function of potential agents for prevention and treatment of HIV-associated OIs and other infections that are modified by HIV infection. (FMB)
Prevention and Treatment of Opportunistic Infection
CL000749
The determination of the amount of any opioid, including any of the naturally occurring and semi-synthetic opiates, fully synthetic opioids and their metabolites, present in a sample.
Opioid Measurement
Opioid Measurement
owl:Class
Laboratory Procedure
CL386353
Opioid Measurement
C74697
Opioid Measurement
CNS Depressant Drug Measurement
C74859
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Laboratory Test Terminology by Name
Glucagon Measurement
C0337437
Clinical Data Interchange Standards Consortium Terminology
GLUCAGON
CDISC SDTM Terminology
Hormone Measurement
Glucagon Measurement
Glucagon Measurement
owl:Class
The determination of the amount of glucagon hormone present in a sample.
CDISC SEND Terminology
Glucagon Measurement
Glucagon
Laboratory Procedure
<def-definition>A measurement of the glucagon hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
Random Sampling
Sampling Method
C53194
C0150105
Random Sampling
Quantitative Concept
owl:Class
Random Sampling
Random Sampling
Cardiac Therapeutic Procedure
owl:Class
C80435
A surgical procedure in which a small, battery-powered device is placed in the chest wall to detect arrhythmias and correct them by delivering a jolt of electricity.
Implantable Cardioverter-Defibrillator Placement
Therapeutic or Preventive Procedure
Implantable Cardioverter-Defibrillator Placement
Implantable Cardioverter-Defibrillator Placement
Implantable Cardioverter-Defibrillator Placement
Instruction Imperative
Dissolve
owl:Class
C64929
Dissolve
CL370154
Dissolve
Activity
Dissolve
Biopsy
Procedure_Has_Partially_Excised_Anatomy only Trachea
Biopsy of Trachea
Diagnostic Procedure
Biopsy of Trachea
C51631
Biopsy of Trachea
owl:Class
Removal of tissue from the trachea for microscopic examination.
CL355005
Biopsy of Trachea
Chemoprevention, Clinical
Clinical Chemoprevention
Chemoprevention
owl:Class
Therapeutic or Preventive Procedure
CL000203
Clinical Chemoprevention
Clinical Chemoprevention
Clinical Chemoprevention
C15782
Chemoprevention use in a clinical setting.
Diagnostic Procedure
C0037296
Diagnostic Procedure
<def-source>NCI-GLOSS</def-source><def-definition>A test for an immune response to a compound by placing it on or under the skin.</def-definition>
skin test
owl:Class
Skin Test
Skin Test
A preparation of an antigenic component of an infectious agent that is administered to a patient in order to determine whether previous exposure to the agent has occurred, and/or to assess the integrity of the patient's cellular immune system. Depending on the clinical situation, the appearance of a delayed (cellular) hypersensitivity response, which manifests as an area of induration and erythema at the injection site, i.e. a positive test result, may indicate previous exposure to a particular infectious agent. (NCI04)
Skin Test
C17137
Skin Test
Phase I and II Vaccine Trials
Select candidate vaccines or concepts suitable for Phase I and Phase II trials and conduct these trials.
Phase I/II Trial
CL000707
Phase I and II Vaccine Trials
Vaccine Clinical Trial
Phase I and II Vaccine Trials
Phase I and II Vaccine Trials
C15835
Research Activity
owl:Class
Nutritional Support
Therapeutic or Preventive Procedure
Supportive Care
Nutritional Support
C0242739
Nutrition Therapy
Nutritional Support
Nutritional Therapy
Nutritional Care
owl:Class
Administration of essential nutrients to a patient utilizing methods other than oral feedings.
C15433
Nutritional Support
Cauchy Distribution
owl:Class
Cauchy Distribution
Cauchy Distribution
C53219
A continuous probability density distribution which models resonance behavior. It is also known as the Lorentz distribution. Its shape is dependent on a location parameter, which specifies the peak of the curve, and a scale parameter which specifies the half-width at half-maximum.
Cauchy Distribution
Continuous Distribution
CL356250
Lorentz Distribution
Quantitative Concept
C16084
observational study
Studies among cancer patients and healthy populations that involve no intervention or alteration in the status of the participants.
Research Activity
<def-source>NCI-GLOSS</def-source><def-definition>A type of study in which individuals are observed or certain outcomes are measured. No attempt is made to affect the outcome (for example, no treatment is given).</def-definition>
Observational Trial
CL008533
Observational Study
Research Activity
Observational Study
Observational Study
owl:Class
Observational Study
Segmental Mastectomy
Procedure_Has_Partially_Excised_Anatomy only Breast
C20749
Mastectomy
Segmental Mastectomy
owl:Class
Segmental Mastectomy
C0024885
Segmental Mastectomy
Therapeutic or Preventive Procedure
Procedure_Has_Partially_Excised_Anatomy only 'Mammary Gland'
The removal of a cancer as well as some of the breast tissue around the tumor and the lining over the chest muscles below the tumor. Usually some of the lymph nodes under the arm are also taken out. Also called partial mastectomy. (Cancer.gov)
segmental mastectomy
Breast Conservation Treatment
<def-source>NCI-GLOSS</def-source><def-definition>(mas-TEK-toe-mee) The removal of a cancer as well as some of the breast tissue around the tumor and the lining over the chest muscles below the tumor. Usually some of the lymph nodes under the arm are also taken out. Also called partial mastectomy.</def-definition>
C45971
C0009219
Administrative Activity
Coding
Coding
Coding
Occupational Activity
Coding
The activity of implementing rules that are used to map the elements of one set onto the elements of another set, usually on a one-to-one basis.
owl:Class
Suction Procedure
Suction Procedure
Surgical Procedure by Method
C0038638
C51939
owl:Class
Suction
Therapeutic or Preventive Procedure
Suction Procedure
Suction Procedure
<def-source>NCI-GLOSS</def-source><def-definition>Surgical removal of the region of the breast (approximately one quarter) containing cancer.</def-definition>
Quadrantectomy
Therapeutic or Preventive Procedure
Breast Conservation Treatment
Quadrantectomy
C15695
owl:Class
Quadrantectomy
CL031852
quadrantectomy
Quadrantectomy
Radioprotection
C15475
Radioprotection
owl:Class
Radioprotection
Therapeutic or Preventive Procedure
Radioprotection
Therapeutic Procedure
CL029173
C0033284
owl:Class
Professional Practice
Professional Practice
Health care professional business directed towards treatment and care of patients.
Professional Practice
Health Care Activity
C52673
Professional Practice
Healthcare Activity
An act or ministration that produces an effect to alter the course of a pathologic process through the use of a variety of media, i.e., CD-ROM, Web application, video, telephone.
owl:Class
Media Intervention
Activity
Media Intervention
Behavioral, Psychological or Informational Intervention
C15813
Media Intervention
Media Intervention
CL000525
C62152
<def-source>CDISC</def-source><def-definition>The average (mean) number of cycles of contraction and subsequent relaxation of the ventricles, usually expressed as beats per minute, obtained from a set of measurements of the ventricular rate. (NCI)</def-definition>
Ventricular Heart Rate
Quantitative Concept
CDISC SDTM Terminology
CDISC SDTM ECG Test Name Terminology
Mean Ventricular Heart Rate
Mean Ventricular Heart Rate
Mean Ventricular Heart Rate
owl:Class
Summary (Mean) Ventricular Rate
The average (mean) number of cycles of contraction and subsequent relaxation of the ventricles, usually expressed as beats per minute, obtained from a set of measurements of the ventricular rate.
CL365064
CDISC
Mean Ventricular Heart Rate
Clinical Data Interchange Standards Consortium Terminology
VRMEAN
CDISC SDTM ECG Test Terminology by Code
C53230
Statistical Test
Quantitative Concept
Parametric Test
CL356710
Parametric Test
Parametric Test
owl:Class
Parametric Test
In statistical inference procedures (hypothesis tests and confidence intervals), parametric procedures are those that incorporate assumptions about population parameters.
Procedure_Has_Excised_Anatomy only Esophagus
owl:Class
Procedure_Has_Excised_Anatomy only Stomach
Therapeutic or Preventive Procedure
Esophagogastrectomy
Esophagogastrectomy
Esophagogastrectomy
Surgical removal of part or all of the esophagus, and part or all of the stomach.
Abdominal Surgical Procedure
Esophagogastrectomy
C51907
CL354552
Cardiac Therapeutic Procedure
Procedure_Has_Completely_Excised_Anatomy only 'Tricuspid Valve'
Cardiovascular Surgical Procedure
Tricuspid Valve Replacement
Tricuspid Valve Replacement
C50816
Therapeutic or Preventive Procedure
Tricuspid Valve Replacement
Tricuspid Valve Replacement
Surgery performed with the purpose of replacing a degenerated, calcified, malformed, dysfunctional, etc. tricuspid valve with bioprosthetic, homograft or autograft valve.
owl:Class
C0190119
Pelvic Examination
owl:Class
Diagnostic Procedure
Pelvic Examination
Pelvic Examination
C38104
Pelvic Examination
Physical Examination
A complete physical examination of a woman's external and internal reproductive organs by a health professional.
Pelvic Exam
C0200045
Quantitative Concept
A probability distribution that arises in the problem of estimating the mean of a normally distributed population when the sample size is small.
t-Distribution
owl:Class
CL356799
C53220
t Distribution
Continuous Distribution
t-Distribution
t-Distribution
t-Distribution
Longitudinal Study
Research Activity
<def-source>MSH2001</def-source><def-definition>Studies in which variables relating to an individual or group of individuals are assessed over a period of time.</def-definition>
<def-source>CDISC</def-source><def-definition>Investigation in which data are collected from a number of subjects over a long period of time (a well-known example is the Framingham Study).</def-definition>
Longitudinal Study
owl:Class
C0023981
<def-source>NCI-GLOSS</def-source><def-definition>In medicine, a study or clinical trial in which participants are identified and then followed forward in time.</def-definition>
CDISC
prospective
C15273
Clinical Data Interchange Standards Consortium Terminology
longitudinal study
Longitudinal Study
Clinical Data Interchange Standards Consortium Glossary Terminology
Longitudinal Study
Study Design
Research Activity
CL004006
Research Activity
Research studies assessing the effect of policies, including worksite, community, state and Federal policies as related to a variety of health issues.
Policy Research
Policy Research
Policy Research
owl:Class
Policy Research
C15999
Laboratory Procedure
Clinical Data Interchange Standards Consortium Terminology
The determination of the ratio of CD19 B cells compared to lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
CDISC SDTM Laboratory Test Terminology by Code
C74635
Blood Cell Count Ratio Measurement
CDISC
CD19 B Cell to Lymphocyte Ratio Measurement
CL384744
CDISC SDTM Terminology
CDISC SEND Terminology
<def-source>CDISC</def-source><def-definition>A relative measurement (ratio or percentage) of CD19 B cells to all lymphocytes in a biological specimen.</def-definition>
CD19 B Cell to Lymphocyte Ratio Measurement
CD19 B Cell to Lymphocyte Ratio Measurement
CD19 B Cell to Lymphocyte Ratio Measurement
CDISC SDTM Laboratory Test Terminology by Name
owl:Class
CD19/Lymphocytes
CD19LY
Arterial Blood Gas Measurement
C0150411
Arterial Blood Gas Measurement
ABG
Blood Gas Measurement
C71252
Blood Chemistry Measurement
Arterial Blood Gas Measurement
Measures the acidity (pH) and the levels of oxygen, carbon dioxide, and bicarbonate in the blood.
Diagnostic Procedure
Blood Gas Analysis
Arterial Blood Gas Measurement
owl:Class
Laboratory Procedure
<def-source>CSP2000</def-source><def-definition>PCR-based method for isolating unique sequences; also, used for comparing differences between two complex genomes.</def-definition>
DNA Analysis
Molecular Biology Research Technique
Representational Difference Analysis
C18114
This PCR technique enables researchers to compare the DNA of normal and afflicted tissue to isolate the DNA regions gained or lost in disease carriers. The essence of the technique is to compare two regions of DNA, one with a "target sequence" and one without. The target sequence may be either DNA added to the genome, by a virus or by genetic amplification, or DNA deleted from a normal chromosome, as in many cancers. Pairing DNA fragments from healthy and diseased tissue allows researchers to quickly identify missing or added DNA sequence and thereby pinpoint genetic alterations that may be involved in disease. (from Cold Spring Harbor)
Representational Difference Analysis
Laboratory Procedure
Representational Difference Analysis
C0597707
owl:Class
Representational Difference Analysis
RDA
Echocardiography
Diagnostic Procedure
<def-source>NCI-GLOSS</def-source><def-definition>A procedure that uses ultrasonic waves directed over the chest wall to obtain a graphic record of the heart's position, motion of the walls, or internal parts such as the valves.</def-definition>
Echocardiography
echocardiography
Echocardiography
C16525
<def-source>MSH2001</def-source><def-definition>Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.</def-definition>
Echocardiography
C0013516
A test that uses high-frequency sound waves (ultrasound) to create an image of the heart.
Cardiac Diagnostic Procedure
owl:Class
Clinical Management
C15931
Clinical Management
Clinical Management
Administrative Activity
Activity
Clinical Management
owl:Class
CL003213
Therapeutic or Preventive Procedure
Acupuncture Therapy
acupuncture
Acupuncture Therapy
<def-source>NCI-GLOSS</def-source><def-definition>The technique of inserting thin needles through the skin at specific points on the body to control pain and other symptoms.</def-definition>
Acupuncture Therapy
C0394664
Acupuncture Therapy
Alternative Medical Procedure
The practice of piercing specific points on the body with very thin sterile needles in order to relieve pain or induce regional anesthesia.
owl:Class
Acupuncture
C15176
C80165
Protein or Enzyme Type Measurement
The determination of the amount of alpha glucuronidase present in a sample.
Alpha Glucuronidase Measurement
Alpha Glucuronidase Measurement
owl:Class
Laboratory Procedure
Alpha Glucuronidase Measurement
Alpha Glucuronidase Measurement
C51486
Biopsy of Conjunctiva
Biopsy of Conjunctiva
CL354439
Biopsy of Conjunctiva
Biopsy
Procedure_Has_Partially_Excised_Anatomy only Conjunctiva
owl:Class
Removal of conjunctival tissue for microscopic examination.
Biopsy of Conjunctiva
Conjunctival Biopsy
Diagnostic Procedure
Cholesterol Crystals
CDISC SDTM Laboratory Test Terminology by Name
owl:Class
CDISC
Cholesterol Crystal Measurement
Crystal Growth Measurement
CDISC SEND Terminology
Laboratory Procedure
CL384771
Clinical Data Interchange Standards Consortium Terminology
Cholesterol Crystal Measurement
The determination of the amount of cholesterol crystals present in a sample.
Cholesterol Crystal Measurement
C74672
CDISC SDTM Terminology
CYCHOL
<def-source>CDISC</def-source><def-definition>A measurement of the cholesterol crystals present in a biological specimen.</def-definition>
CDISC SDTM Laboratory Test Terminology by Code
Cholesterol Crystal Measurement
owl:Class
C0009542
C70611
Total Hemolytic Complement Assay
Complement Hemolytic Activity Assay
Complement Hemolytic Activity Assay
Laboratory Procedure
A screening assay for circulating complement proteins in which diluted serum samples are added to antibody-coated erythrocytes and the percentage of cell lysis is measured. The values are expressed in hemolytic complement units per milliliter (CH50), the dilution of serum required to lyse 50 percent of the erythrocytes in the assay.
Diagnostic Procedure
Complement Hemolytic Activity Assay
Hematology Test
Complement Hemolytic Activity Assay
CH50
CL052669
Send
Send
C25672
Action
owl:Class
Functional Concept
Sent
Cause or enable to go or be conveyed or transmitted.
Send
Send
owl:Class
Cancer Screening
Cancer Screening
The use of any device, marker, or other means for the purpose of detecting the presence of a tumor, usually before there are any symptoms.
C0199230
Diagnostic Procedure
Early Cancer Detection
Disease Screening
Cancer Screening
C15406
Cancer Screening
Screening of Cancer
Cancer Screening for Patients
Raman Spectroscopy
Spectroscopy, IR/UV/Raman
Spectroscopy, Raman
Spectroscopy
Emission of electromagnetic energy with a shorter frequency (longer wavelength) than that of the incident monochromatic light. Arises from the low probability absorption of quanta with a higher energy than that required for a transition: the difference in energy is emitted as a lower frequency (energy) photon. Allows analysis of vibrational and rotational energy levels using visible incident light.
Raman Spectroscopy
C17157
<def-source>MSH2001</def-source><def-definition>Analysis of the intensity of Raman scattering of monochromatic light as a function of frequency of the scattered light.</def-definition>
Raman Spectroscopy
Laboratory Procedure
Raman Spectroscopy
C0037815
owl:Class
The determination of the amount of neutrophil elastase present in a sample.
Neutrophil Elastase Measurement
Neutrophil Elastase Measurement
C82026
owl:Class
Neutrophil Elastase Measurement
Protein or Enzyme Type Measurement
Neutrophil Elastase Measurement
Mental Process
Imagery Therapy
A therapeutic exercise used in treatment of pain, hyperventilation, panic, and other conditions. The practitioner guides the patient into a semi-hypnotic state by verbally introducing positive and soothing images. It is as a form of distraction and attention therapy.
imagery
<def-source>NCI-GLOSS</def-source><def-definition>A technique in which the person focuses on positive images in his or her mind.</def-definition>
C15375
C0150627
Guided Imagery
Imagery Therapy
Imagery
Imagery Therapy
Mind-Body Intervention Procedure
owl:Class
Imagery Therapy
Cholecystectomy
Surgical removal of the gallbladder.
Procedure_Has_Excised_Anatomy only Gallbladder
C51676
Cholecystectomy
CL355030
Cholecystectomy
Abdominal Surgical Procedure
Cholecystectomy
Therapeutic or Preventive Procedure
owl:Class
Continuum Modeling
Continuum Modeling
Research Activity
Continuum Modeling
CL384622
C75361
Modeling
owl:Class
Continuum Modeling
The mathematical practice of applying a model to continuous data which has a potentially infinite number, and divisibility, of attributes.
Substitution
Qualitative Concept
The act of putting one thing or person in the place of another.
Substitution
owl:Class
Substitution
C54071
Substitution
C1555721
Change
C0086750
Outcomes Research
Outcomes Research
owl:Class
Health Care Activity
Outcomes and Health Services Research
Research Activity
Outcomes Research
C15365
<def-source>CSP2000</def-source><def-definition>research aimed at assessing the quality and effectiveness of health care as measured by the attainment of a specified end result or outcome; for complete retrieval include RTs.</def-definition>
Outcomes Research
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
CDISC
Leukocyte Esterase Measurement
Laboratory Procedure
LEUKASE
<def-source>CDISC</def-source><def-definition>A measurement of the enzyme which indicates the presence of white blood cells in a biological specimen.</def-definition>
Leukocyte Esterase Measurement
CDISC SDTM Terminology
C0427760
Leukocyte Esterase
Leukocyte Esterase Measurement
C64856
Leukocyte Esterase Measurement
Protein or Enzyme Type Measurement
owl:Class
CDISC SEND Terminology
A quantitative measurement of the amount of leukocyte esterase present in a sample.
C74668
<def-source>CDISC</def-source><def-definition>A measurement of the bilirubin crystals present in a biological specimen.</def-definition>
CL384767
CDISC SDTM Terminology
CDISC SEND Terminology
Bilirubin Crystal Measurement
CDISC SDTM Laboratory Test Terminology by Code
Bilirubin Crystal Measurement
CDISC
owl:Class
Crystal Growth Measurement
The determination of the amount of bilirubin crystals present in a sample.
CYBILI
Laboratory Procedure
Clinical Data Interchange Standards Consortium Terminology
Bilirubin Crystal Measurement
Bilirubin Crystal Measurement
Bilirubin Crystals
CDISC SDTM Laboratory Test Terminology by Name
C0007703
Centrifugation
owl:Class
C16410
Fractionation, Centrifugation
Centrifugation
Centrifugation
Process of using a rotating machine to generate centrifugal force to separate substances of different densities, remove moisture, or simulate gravitational effects. It employs a large motor-driven apparatus with a long arm, at the end of which human and animal subjects, biological specimens, or equipment can be revolved and rotated at various speeds to study gravitational effects. (From Websters, 10th ed; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Biomolecule Separations Technology
Laboratory Procedure
Centrifugation
owl:Class
Therapeutic or Preventive Procedure
Myeloablative Chemotherapy
Myeloablative Chemotherapy
C16231
The administration of high-dose chemotherapy, with or without total body irradiation, to eradicate the underlying disease and/or ablate the immune system of the patient.
Myeloablative Chemotherapy
CL027666
Myeloablative Chemotherapy
Bone Marrow Ablation
C64868
Animal-Assisted Therapy
Health Care Activity
Animal-Assisted Therapy
Pet Therapy
Pet-Facilitated Therapy
owl:Class
CL370492
Animal-Assisted Therapy
Animal-Assisted Therapy
Mind-Body Intervention Procedure
Behavioral, Psychological or Informational Intervention
Informational Intervention
Informational Intervention
C64255
owl:Class
CL369091
Informational Intervention
Health Care Activity
Informational Intervention
Reintubation Procedure
Reintubation Procedure
Reintubation Procedure
owl:Class
CL355446
Therapeutic or Preventive Procedure
Reintubation Procedure
Intubation Procedure
C50828
Reintubation
Research Technique
Biomolecule Separations Technology
C18653
owl:Class
CL000108
Biomolecule Separations Technology
Techniques for separating biomolecules from suspensions or mixtures, based on physical and chemical properties. Such techniques include ion exchange columns, gel filtration methods, affinity chromatography, HPLC, aqueous two phase partitioning, and membrane separation.
Biomolecule Separations Technology
Biomolecule Separations Technology
Laboratory Procedure
The act of altering the size of an object.
Scaling
Scaling
C67036
Scaling
Action
owl:Class
Scale
CL371589
Scaling
Activity
Mass Spectrometry
CL336491
Surface-Enhanced Laser Desorption/Ionization-Time of Flight Mass Spectrometry
Surface-Enhanced Laser Desorption/Ionization-Time of Flight Mass Spectrometry
owl:Class
SELDI-TOF-MS
Laboratory Procedure
Surface-Enhanced Laser Desorption/Ionization-Time of Flight Mass Spectrometry
Surface-Enhanced Laser Desorption/Ionization-Time of Flight Mass Spectrometry
C62672
SELDI-TOF
Idea or Concept
Clinical Diagnosis
Clinical Diagnosis
C0332140
C15607
owl:Class
Diagnosis
Clinical Diagnosis
A diagnosis made from a study of the signs and symptoms of a disease.
Clinical Diagnosis
Cytokine Measurement
CDISC SDTM Laboratory Test Terminology by Name
CL384301
INTLK23
Laboratory Procedure
owl:Class
<def-definition>A measurement of the interleukin 23 in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SEND Terminology
The determination of the amount of interleukin 23 present in a sample.
Interleukin 23 Measurement
C74820
Interleukin 23 Measurement
CDISC SDTM Terminology
Clinical Data Interchange Standards Consortium Terminology
Interleukin 23 Measurement
Interleukin 23 Measurement
Interleukin 23
CDISC SDTM Laboratory Test Terminology by Code
Action Taken with Pharmacological Treatment
Activity
The reason that changes were made to the specific pharmacologic therapy under study.
Pharmacotherapy
Action Taken with Pharmacological Treatment
CL354879
C49500
Action Taken with Pharmacological Treatment
Action Taken with Pharmacological Treatment
owl:Class
Statistical Imputation
Mean Observed Value in a Group Imputation Technique
Quantitative Concept
The substitution of missing data with the mean value from a group of subjects.
Mean Observed Value in a Group Imputation Technique
C81207
owl:Class
Mean Observed Value in a Group Imputation Technique
Mean Observed Value in a Group Imputation Technique
C82036
owl:Class
Tissue Inhibitor of Metalloproteinase 1 Measurement
Protein or Enzyme Type Measurement
Tissue Inhibitor of Metalloproteinase 1 Measurement
Tissue Inhibitor of Metalloproteinase 1 Measurement
The determination of the amount of tissue inhibitor of metalloproteinase 1 present in a sample.
Tissue Inhibitor of Metalloproteinase 1 Measurement
Sigmoidoscopy with Biopsy
Endoscopic Biopsy
Sigmoidoscopy with Biopsy
Sigmoidoscopy with Biopsy
C51592
Sigmoidoscopy with Biopsy
Procedure_Has_Partially_Excised_Anatomy only 'Sigmoid Colon'
Removal of tissue from the sigmoid colon for microscopic examination, using an endoscope.
CL354227
Diagnostic Procedure
owl:Class
Biomedical Research
Biomedical Research
Biomedical Research
Research Activity
Biomedical Research
C15188
owl:Class
Research Activity
Research concerned with the application of biological and physiological principles to clinical medicine.
C0005540
Dietary Practices
Dietary Practices
Personal Behavior
Dietary Practices refers to a person's choices in food consumption.
C19706
Individual Behavior
Dietary Practices
owl:Class
Dietary Practices
CL008603
CL001074
C15872
Health Care Activity
Vaccine Related Non-Development, Non-AIDS
owl:Class
Vaccine Related Non-Development, Non-AIDS
Vaccine Related Non-Development, Non-AIDS
Vaccine Development
Vaccine Related Non-Development, Non-AIDS
CL052268
Clinical Trial Eligibility Criteria
<def-source>CDISC</def-source><def-definition>The criteria in a protocol that prospective subjects must meet to be eligible for participation in a study. NOTE: Exclusion and inclusion criteria define the study population. See also exclusion criteria. (CDISC glossary)</def-definition>
C25532
Inclusion Criteria
CDISC
CDISC SDTM Terminology
Inclusion Criteria
Inclusion Criteria
Medical and/or social characteristics which are necessary for a subject to be allowed to participate in a clinical study, as outlined in the study protocol. Meeting inclusion criteria is not a sufficient condition for entry or recruitment of a subject into the study. Characteristics limiting the eligibility of a subject for the clinical study must be considered.
INCLUSION
CDISC SDTM Category for Inclusion And Or Exclusion Terminology
Inclusion Criteria
Functional Concept
Clinical Data Interchange Standards Consortium Terminology
owl:Class
C16326
Behavior
Behavior
Behavior
Behavior
Behavioral
Conduct
owl:Class
Behavior
The actions or reactions of an object or organism, usually in relation to the environment or surrounding world of stimuli.
Activity
C0004927
Clinical Attribute
C15500
owl:Class
Prior Hormone Therapy
Prior Estrogen Therapy
CL029655
Prior Estrogen Therapy
Prior Estrogen Therapy
Prior Estrogen Therapy
Research Activity
Smoking and Health Research
Smoking and Health Research
Smoking and Health Research
Smoking and Health
C15922
Research Activity
Research focusing on all activities associated with tobacco smoking; concerns factors that influence individuals to start or stop smoking, how these factors differ by age, sex, ethnic group, educational or socioeconomic level, etc.
CL003092
owl:Class
Smoking and Health Research
Shopping
Physical Activity
C81006
Shopping
Shop
The act of searching for or buying goods or services.
owl:Class
Shopping
Shopping
Daily or Recreational Activity
Ketone Measurement
Ketone Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the ketones in a biological specimen.</def-definition>
CDISC SEND Terminology
C64854
CL035884
Clinical Data Interchange Standards Consortium Terminology
Ketone Measurement
KETONES
CDISC
Ketones
Chemistry Test
A quantitative measurement of the amount of ketones present in a sample.
CDISC SDTM Terminology
owl:Class
CDISC SDTM Laboratory Test Terminology by Code
Ketone Measurement
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
Synchrotron X-Ray Diffraction
Synchrotron X-Ray Diffraction
Research Technique
Synchrotron X-Ray Diffraction
Laboratory Procedure
CL370988
Synchrotron X-Ray Diffraction
owl:Class
C66898
Laboratory Procedure
owl:Class
Antipsychotic Measurement
The determination of the amount of any antipsychotic drug present in a sample.
CL384605
Antipsychotic Measurement
Antipsychotic Measurement
C75344
CNS Affecting Drug Measurement
Antipsychotic Measurement
Procedure_Has_Target_Anatomy only Stomach
Roux-en-Y Anastomosis
Roux-en-Y
owl:Class
Therapeutic or Preventive Procedure
Roux-en-Y Anastomosis
Roux-en-Y Anastomosis
Procedure_Has_Target_Anatomy only 'Small Intestine'
CL355479
C51756
Gastric bypass procedure in which part of the stomach is closed off with staples, and part of the small intestine is bypassed. This procedure is performed in severely obese patients, for permanent weight loss.
Roux-en-Y Anastomosis
End-to-Side Anastomosis
C15649
Diet Research
owl:Class
Research Activity
Diet Research
Nutritional Study
Diet Research
Diet Research
CL111076
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Name
Barbiturate Drug Class Measurement
Barbiturate Drug Class Measurement
owl:Class
C0391936
CDISC SEND Terminology
Barbiturates
Barbiturate Drug Class Measurement
Clinical Data Interchange Standards Consortium Terminology
CDISC
C74688
Barbiturate Drug Class Measurement
BARB
<def-source>CDISC</def-source><def-definition>A measurement of any barbiturate class drug present in a biological specimen.</def-definition>
CDISC SDTM Terminology
CNS Depressant Drug Measurement
CDISC SDTM Laboratory Test Terminology by Code
The determination of the amount of barbiturate class agents present in a sample.
CL378512
Action
Sweep
C72075
Activity
owl:Class
A movement in an arc over a specified body part or area.
Sweep
Sweep
Sweep
Disposal
Disposal Technique
C48166
owl:Class
Disposal
Activity
Action
Disposal
Disposal
CL342957
The act or means of getting rid of something.
CL035543
Bronchoscopic and Lung Imaging Study
Bronchoscopic and Lung Imaging Study
Bronchoscopic and Lung Imaging Studies
Bronchoscopic and Lung Imaging Study
Diagnostic Procedure
Bronchoscopic and Lung Imaging Study
C62684
owl:Class
Image Study
The determination of the amount of interferon beta present in a sample.
Interferon Beta Measurement
Interferon Beta Measurement
Interferon Measurement
Interferon Beta Measurement
C81995
owl:Class
Interferon Beta Measurement
Plasminogen Activator Inhibitor-1 Antigen Measurement
Immunology Test
The determination of the amount of plasminogen activator inhibitor-1 antigen present in a sample.
Plasminogen Activator Inhibitor-1 Antigen Measurement
Plasminogen Activator Inhibitor-1 Antigen Measurement
Plasminogen Activator Inhibitor-1 Antigen Measurement
C81989
owl:Class
Large-Scale Sequencing
C19645
Molecular Biology Research Technique
Nucleic Acid Sequencing
Large-Scale Sequencing
CL008155
Laboratory Procedure
Large-Scale Sequencing
owl:Class
The process of determining of the precise sequence of nucleotides over a very large piece of DNA, possibly the entire genome of an organism.
Large-Scale Sequencing
CDISC SDTM Terminology
Granular Cast Measurement
Laboratory Procedure
C74768
Granular Cast Measurement
Clinical Data Interchange Standards Consortium Terminology
CL384283
CDISC SDTM Laboratory Test Terminology by Name
CDISC
CDISC SEND Terminology
The determination of the amount of granular casts present in a urine sample.
CSGRAN
Urine Sediment Analysis Measurement
Granular Casts
<def-definition>A measurement of the granular (coarse and fine) casts present in a urine specimen.</def-definition><def-source>CDISC</def-source>
Granular Cast Measurement
owl:Class
CDISC SDTM Laboratory Test Terminology by Code
Granular Cast Measurement
Unilateral Ovariectomy
Surgery to remove one ovary.
Therapeutic or Preventive Procedure
ovariectomy - unilateral
C29892
C0041687
Unilateral Oophorectomy
Unilateral Oophorectomy
Unilateral Oophorectomy
owl:Class
Unilateral Oophorectomy
Oophorectomy
Marsupialization
Epithelial Marsupialization
Epithelial Marsupialization
Epithelial Marsupialization
Therapeutic or Preventive Procedure
C50829
Surgical Procedure by Method
Epithelial Marsupialization
owl:Class
CL355101
Periodontal Treatment
Periodontal Treatment
C63747
Therapeutic or Preventive Procedure
Dental Procedure
Periodontal Treatment
Periodontal Procedure
Periodontal Treatment
Treatment of the gums, soft tissues, and bones that support the teeth.
CL366418
owl:Class
HIV DRP
Research Activity
HDRP
HIV Drug Resistance Program
C16101
CL008714
HIV Drug Resistance Program
HIV Drug Resistance Program
Infectious Diseases Research
HIV Drug Resistance Program
This HIV initiative will create a center for retrovirology research, with emphasis on basic and translational research related to viral evolution and resistance biology. Scientific issues to be addressed in solving the problem of HIV drug resistance will require the coordinated efforts of experts in structural biology and biochemistry, molecular and clinical or in vivo virology, epidemiology, and chemistry. The new program also will include animal model studies of population dynamics and population genetics of HIV, mathematical modeling of virus populations and evolution, and, ultimately, translation of the findings into drug development.
owl:Class
owl:Class
Pulpotomy
C0034104
C62549
Pulpotomy
Pulpotomy
Pulpotomy
Therapeutic or Preventive Procedure
Dental Procedure
Surgical amputation of the coronal portion of the dental pulp.
Thoracic Surgical Procedure
C51651
Pleurectomy
owl:Class
Therapeutic or Preventive Procedure
Pleurectomy
C0152463
Excision of Pleura
Pleurectomy
Procedure_Has_Excised_Anatomy only Pleura
Pleurectomy
The determination of the amount of dihydrotestosterone hormone present in a sample.
Dihydrotestosterone Measurement
Hormone Measurement
CDISC SDTM Laboratory Test Terminology by Code
Dihydrotestosterone Measurement
C74853
Dihydrotestosterone Measurement
CDISC SEND Terminology
Androstanalone
DHT
Dihydrotestosterone
<def-definition>A measurement of the dihydrotestosterone hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
Laboratory Procedure
Clinical Data Interchange Standards Consortium Terminology
owl:Class
CDISC SDTM Terminology
C0373601
Dihydrotestosterone Measurement
CDISC SDTM Laboratory Test Terminology by Name
C54178
C0597428
Sedimentation
Biomolecule Separations Technology
Sedimentation
Sedimentation
Laboratory Procedure
Sedimentation
owl:Class
The act or process of settling particles by mechanical means from a state of suspension in air or water.
CL014622
Originally, therapeutic administration of serum or gamma globulin containing preformed antibodies produced by another individual; currently, immunotherapy includes nonspecific systemic stimulation, adjuvants, active specific immunotherapy, and adoptive immunotherapy. New forms of immunotherapy include the use of monoclonal antibodies. This approach has been widely adopted by cancer specialists, often in cases which fail to respond to other treatment. Immunotherapy aims to boost immune system function, as with the administration of interferons and interleukin-2, or to attack cancerous cells directly, as with the injection of monoclonal antibodies. Various immunotherapeutic techniques have also been employed among AIDS patients. In addition, a number of alternative medical practices are claimed to enhance immune function, and various over-the-counter substances (e.g., goldenseal, lysine have gained popularity for this supposed property.
Prior Immunotherapy
Prior Therapy
owl:Class
Prior Immunotherapy
Prior Immunotherapy
Clinical Attribute
Prior Immunotherapy
C16168
CL383361
Soybean Lectin Agglutination
Soybean Lectin Agglutination
C72902
Laboratory Procedure
Soybean Lectin Agglutination
A technique for removing T lymphocytes based on differential agglutination with soybean lectin.
owl:Class
Soybean Lectin Agglutination
Hematology Test
C74848
Calcitonin Measurement
C0201924
Calcitonin
Clinical Data Interchange Standards Consortium Terminology
CDISC SEND Terminology
Calcitonin Measurement
The determination of the amount of calcitonin hormone present in a sample.
CDISC SDTM Laboratory Test Terminology by Code
owl:Class
Hormone Measurement
CDISC SDTM Terminology
CLCTONN
Calcitonin Measurement
CDISC SDTM Laboratory Test Terminology by Name
<def-definition>A measurement of the calcitonin hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
Calcitonin Measurement
Laboratory Procedure
The determination of the amount of complement C3a present in a sample.
Complement C3a Measurement
Laboratory Procedure
Complement C3a Measurement
owl:Class
Complement C3a Measurement
Complement Measurement
Complement C3a Measurement
C80175
Phospho-AKT Immunohistochemical Expression Analysis
C80276
Laboratory Procedure
Phospho-AKT Immunohistochemical Expression Analysis
Phospho-AKT Immunohistochemical Expression Analysis
Immunohistochemical Test
Phospho-AKT Immunohistochemical Expression Analysis
owl:Class
pAKT Immunohistochemical Expression Analysis
Bioconductor caAffy Quantiles Robust Normalization
Statistical Technique
Bioconductor caAffy Quantiles Robust Normalization
Bioconductor caAffy Quantiles Robust Normalization
CL369469
C63936
owl:Class
A method for normalization based upon the concept of a quantile-quantile plot extended to n dimensions. Defined in documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html
Bioconductor caAffy Quantiles Robust Normalization
Activity
Diagnostic Procedure
Medical Imaging, Virtual Reality
owl:Class
Medical Imaging, Virtual Reality
Virtual reality in Medical Imaging is the technique of combining 3D DICOM image data sets produced by medical imaging equipment with extremely high-powered computer capabilities. Virtual reality employs medical images as a foundation to create innovative methods of reviewing and analyzing the data they produce.
CL000529
Medical Imaging, Virtual Reality
C18869
Medical Imaging, Virtual Reality
Imaging Technique
Lobectomy
Lobectomy
C15272
Therapeutic or Preventive Procedure
owl:Class
Lobectomy
Surgical removal of a lobe of an organ.
C0023928
lobectomy
Excision
Lobectomy
<def-source>NCI-GLOSS</def-source><def-definition>(lo-BEK-toe-mee) The removal of a lobe.</def-definition>
Gene Amplification or Deletion Detection
Gene Amplification Deletion and Detection
owl:Class
Molecular Biology Research Technique
Gene Amplification or Deletion Detection
Laboratory Procedure
C19133
DNA Analysis
CL001120
Gene Amplification or Deletion Detection
Gene Amplification or Deletion Detection
Typically, the use of hybridization techniques to detect amplification or deletion of specific DNA sequences. The hybridization signal of a specific sequence is compared to that of a reference sequence, usually one known to be present once per haploid genome.
CL323827
Light exercise for less than 20 minutes, 20-60 minutes of exercise which elevates your heart rate to less than 35% of your maximum heart rate, or light exercise less than 3 times per week.
Daily or Recreational Activity
Very Light Exercise
Exercise
owl:Class
Very Light Activity
Very Light Exercise
Very Light Exercise
Maximum heart rate is approximately 220 minus current age in years.
Very Light Exercise
Sedentary Exercise
C39777
Urine Magnesium Measurement
Urine Magnesium Measurement
C0428308
C61049
Laboratory Procedure
Urine Magnesium Measurement
owl:Class
Urine Magnesium Measurement
A quantitative measurement of the total amount of magnesium present in a sample of urine.
Urine Chemistry Measurement
Magnesium Measurement
C1511524
Correlative Study
Correlative
C16100
Correlative Study
Research Activity
Correlative Study
A type of study that tests for a relationship between a condition and a potential causal factor of the condition.
owl:Class
Translational Research
Correlative Study
incision of the mediastinum
Mediastinotomy
Surgical opening of the mediastinum.
Thoracotomy
Mediastinotomy
Therapeutic or Preventive Procedure
owl:Class
Mediastinotomy
Mediastinotomy
C0198402
Procedure_Has_Target_Anatomy only Mediastinum
C15404
Blinded Clinical Study
Blinded Clinical Study
CL375940
Blinded Clinical Trial
Masked Clinical Study
Clinical Study by Design
Research Activity
Blinded Clinical Study
C70840
Blind Clinical Study
A clinical study that is designed using a procedure in which one or more parties to the study [subject(s), investigator(s), monitor, or/and data analyst(s)] are kept unaware of the treatment assignment(s).
Blinded Clinical Study
owl:Class
CL356795
Quantitative Concept
Wilcoxon Signed Rank Test
Non-Parametric Test
Wilcoxon Signed Rank Test
Wilcoxon Signed Rank Test
Wilcoxon Signed Rank Test
owl:Class
Wilcoxon Test
The Wilcoxon signed ranks test is aimed at testing a null hypothesis from paired replicates data - that both treatments are equivalent. This test is based on one of the two Wilcoxon rank sums as the test statistic. The Wilcoxon signed ranks test allows you to utilize information about order (rank) of the magnitude of the difference between two replicated measurements. In other words, this test gives more weight to the pairs of measurements which show higher difference. Note that this test does not use the absolute magnitude of the difference, just its rank. In other words, a difference of 4 is considered larger than a difference of 2, but not twice as large, nor 2 units larger. This is a nonparametric test.
C53246
Childhood Cancer Survivor Study
Research Activity
Childhood Cancer Survivor Study
An NCI-funded multi-institution project designed to better understand late effects of cancer upon cancer survivors
Cancer Survivorship Research
Childhood Cancer Survivor Study
owl:Class
Outcomes Research
Childhood Cancer Survivor Study
CL008241
CCSS
C16076
Urine Potassium Measurement
A quantitative measurement of the total amount of potassium present in a sample of urine.
Urine Potassium Measurement
C61047
Urine Chemistry Measurement
Urine Potassium Measurement
Potassium Measurement
Urine Potassium Measurement
owl:Class
Laboratory Procedure
C0202195
A preliminary test for cancer of the uterine cervix in which the cervix is painted with an aqueous solution of iodine and potassium iodide and which shows up healthy tissue by staining it brown and possibly cancerous tissue as white or yellow due to its failure to take up the stain because of a deficiency of glycogen in the cells. It was introduced by Walter Schiller, an american pathologist, in 1933. (from fasthealth.com)
Schiller's Test
<def-source>NCI-GLOSS</def-source><def-definition>(SHIL-er) A test in which iodine is applied to the cervix. The iodine colors healthy cells brown; abnormal cells remain unstained, usually appearing white or yellow.</def-definition>
Diagnostic Procedure
Schiller Test
Schiller Test
Schiller test
Schiller Test
Schiller Test
owl:Class
C20643
CL096590
Diagnostic Procedure
Multicenter Hemophilia Cohort Study
CL000535
Infectious Diseases Research
Multicenter Hemophilia Cohort Study
MHCS-I
Multicenter Hemophilia Cohort Study
owl:Class
Health Care Activity
Multicenter Hemophilia Cohort Study
MHCS
C15814
A multi-center study of HIV disease progression and heterosexual transmission begun in 1982.
Radiation Therapy
therapy, neutron
neutron therapy
Therapeutic or Preventive Procedure
owl:Class
CL028895
High-LET Neutron Therapy
therapy, high-LET neutron
High-LET Neutron Therapy
C15440
High-LET Neutron Therapy
High-LET Neutron Therapy
C16205
Healthcare Activity
Clinical or Research Activity
Healthcare Activity
Healthcare
Healthcare Activity
Health Care Activity
Health Care Activity
CL024569
The actions of prevention, treatment, and management of illness and the preservation of mental and physical well-being through the services offered by the medical and allied health professions.
Healthcare Activity
owl:Class
Preventive Intervention
owl:Class
Preventative Dietary Intervention
Preventative Dietary Intervention
CL370339
Therapeutic or Preventive Procedure
Preventative Dietary Intervention
Preventative Dietary Intervention
C64891
Dietary Intervention
Therapeutic or Preventive Procedure
Laparoscopic Appendectomy
CL353500
Laparoscopic Appendectomy
owl:Class
Laparoscopic Appendectomy
Appendectomy
Surgical removal of the vermiform appendix, using a laparoscope.
Laparoscopic Appendectomy
Therapeutic Laparoscopic Surgery
C51893
cDNA Microarray Analysis
Laboratory Procedure
Complementary DNA (cDNA) clone inserts robotically printed onto a glass slide and subsequently hybridized to two differentially fluorescently labeled probes. The probes are pools of cDNAs, which are generated after isolating mRNA from cells or tissues in two states that one wishes to compare.
cDNA Microarray
cDNA Microarray Analysis
cDNA Microarray Analysis
cDNA Microarray Analysis
CL102006
owl:Class
C25866
DNA Microarray Analysis
Amino Acid Injection
owl:Class
C0280081
Therapeutic or Preventive Procedure
Amino Acid Injection
C15509
A type of nutritional support consisting of a mixture of various animo acids in solution.
Amino Acid Injection
Nutritional Support
Amino Acid Injection
CL343425
Therapeutic or Preventive Procedure
Pulmonary Complications Management
Supportive Care
C62746
Pulmonary Complications Management
owl:Class
Pulmonary Complications Management
Pulmonary Complications Management
owl:Class
Health Care Activity
Eligibility Determination
Eligibility Determination
Protocol Screening
Eligibility
C25171
C0013893
Eligibility Determination
The act of determining if a subject is suitable for enrollment in a study according specific protocol criteria and procedures.
Clinical Trials Design
Eligibility Determination
In Situ Photoimmunotherapy
In Situ Photoimmunotherapy
CL370840
In Situ Photoimmunotherapy
C66920
Therapeutic or Preventive Procedure
In Situ Photoimmunotherapy
Photoimmunotherapy
owl:Class
Molecular Biology Research Technique
Electrophoresis
Immunoelectrophoresis
Immunoelectrophoresis
owl:Class
CL355205
Immunoelectrophoresis
Immunoelectrophoresis
C51958
CDISC
Laboratory Procedure
Yeast Cell Measurement
Cell Count
CDISC SDTM Terminology
Yeast Cell Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the yeast cells present in a biological specimen.</def-definition>
Yeast Cell Measurement
YEAST
CL384355
CDISC SDTM Laboratory Test Terminology by Name
Yeast Cells
CDISC SEND Terminology
owl:Class
Yeast Cell Measurement
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
The determination of the number of yeast cells present in a sample.
C74664
CL003631
FTOC
Fetal Thymic Organ Culture
Fetal Thymic Organ Culture
Organ Culture
Fetal Thymic Organ Culture. A cell culture system where fetal thymic cells are grown in vitro.
Laboratory Procedure
Fetal Thymic Organ Culture
owl:Class
C19299
Fetal Thymic Organ Culture
CL378118
Homogeneous Sample Selection
C71507
Homogeneous Sample Selection
Matched Sampling
Homogeneous Sample Selection
Homogeneous Sample Selection
Quantitative Concept
owl:Class
C68769
Decontamination
To rid of contamination.
Decontamination
Decontamination
Decontaminate
owl:Class
Action
Decontamination
Activity
C0011121
Dental Impression
CL383675
Dental Impression
owl:Class
Dental Impression
Dental Impression
C73514
Dental Procedure
A procedure used to acquire a negative reproduction of an oral structure for the purpose of producing a positive model or cast of the structure upon which restorations, prostheses, and dentures are fabricated.
Therapeutic or Preventive Procedure
Chromosomal Translocation Analysis
C80147
owl:Class
t(14;18) Status Analysis
t(14;18) Status Analysis
Laboratory Procedure
t(14;18) Status Analysis
t(14;18) Status Determination
t(14;18) Status Analysis
CL356027
Surgical removal of the right fallopian tube and right ovary.
Right Salpingo-Oophorectomy
Procedure_Has_Excised_Anatomy only 'Right Fallopian Tube'
owl:Class
C51926
Procedure_Has_Excised_Anatomy only 'Right Ovary'
Right Salpingo-Oophorectomy
Therapeutic or Preventive Procedure
Right Salpingo-Oophorectomy
Right Salpingo-Oophorectomy
Salpingo-Oophorectomy
owl:Class
Beta Glucuronidase Measurement
Beta Glucuronidase Measurement
Beta Glucuronidase Measurement
The determination of the amount of beta glucuronidase present in a sample.
Protein or Enzyme Type Measurement
C80170
Beta Glucuronidase Measurement
Laboratory Procedure
owl:Class
C0029216
organ grafting
Organ Transplantation
Organ Transplantation
Clinical, Transplantation, Organ
Procedure_Has_Target_Anatomy only Organ
Therapeutic Surgical Procedure
Organ Transplantation
Surgical Procedure by Site or System
The transfer of an organ (or part of one) from one body to another, for the purpose of replacing the recipient's damaged or failing organ with a working one from the donor. Donors can be living, or cadaveric (dead).
C15289
Organ Transplantation
Transplantation
Therapeutic or Preventive Procedure
Organ Transplants
Thymidylate Synthase Measurement
owl:Class
Thymidylate Synthase Measurement
Laboratory Procedure
Thymidylate Synthase Measurement
Chemistry Test
Thymidylate Synthase Measurement
C81727
Interleukin 16 Measurement
CDISC SDTM Laboratory Test Terminology by Name
Interleukin 16 Measurement
CDISC SDTM Laboratory Test Terminology by Code
Interleukin 16 Measurement
Laboratory Procedure
The determination of the amount of interleukin 16 present in a sample.
C74812
Cytokine Measurement
Interleukin 16
CDISC SDTM Terminology
owl:Class
CL384293
Clinical Data Interchange Standards Consortium Terminology
<def-definition>A measurement of the interleukin 16 in a biological specimen.</def-definition><def-source>CDISC</def-source>
Interleukin 16 Measurement
INTLK16
CDISC SEND Terminology
Urine Chemistry Measurement
CDISC SDTM Laboratory Test Terminology by Code
Hippuric Acid Crystal Measurement
CYHIPPAC
The determination of the amount of hippuric acid crystals present in a urine sample.
Laboratory Procedure
CDISC
Crystal Growth Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the hippuric acid crystals present in a urine specimen.</def-definition>
CDISC SDTM Terminology
owl:Class
Hippuric Acid Crystal Measurement
CDISC SDTM Laboratory Test Terminology by Name
Hippuric Acid Crystal Measurement
Clinical Data Interchange Standards Consortium Terminology
Hippuric Acid Crystal Measurement
CL384401
C74754
CDISC SEND Terminology
Hippuric Acid Crystals
Urine Calcium Measurement
Urine Calcium Measurement
Urine Chemistry Measurement
C61046
Urine Calcium Measurement
Calcium Measurement
A quantitative measurement of the total amount of calcium present in a sample of urine.
owl:Class
Laboratory Procedure
C0428303
Urine Calcium Measurement
Special Populations Research
Population Study
CL014096
C16137
Special Populations Research
Research Activity
owl:Class
Special Populations Research
Multidisciplinary research aimed at addressing and modifying the excessive cancer incidence and/or mortality rates, the lower cancer survival rates, or the inadequate cancer prevention and control services for special populations. The term "special populations" refers to those population segments that may experience, or are known to experience, high cancer rates and/or are underserved in terms of cancer prevention and control programs. Special populations include Alaskan natives, American Indians, Hispanics, Asian- Americans, Blacks, blue-collar groups, the elderly, lower-income groups, native Hawaiians, and American Samoans. (DEA-CAACT)
Special Populations Research
C62745
Osteoporosis Management
CL365791
Osteoporosis Management
Therapeutic or Preventive Procedure
owl:Class
Osteoporosis Management
Osteoporosis Management
Musculoskeletal Complications Management
Stereotactic Radiation Therapy
Therapeutic or Preventive Procedure
C67225
Radiation Therapy
Stereotactic Radiation Therapy
Stereotactic Radiation Therapy
Stereotactic Radiotherapy
owl:Class
Stereotactic Radiation Therapy
C1273404
owl:Class
Pain Therapy
C0002766
Pain Control
Pain Therapy
(i) the systematic study of clinical and basic science and its application for the reduction of pain and suffering; (ii) the blending of tools, techniques and principles taken from the discrete healing art disciplines and reformulated as a holistic application for the reduction of pain and suffering; and (iii) a newly emerging discipline emphasizing an interdisciplinary approach with a goal of reduction of pain and suffering. (AAPM)
Pain Therapy
Supportive Care
Therapeutic or Preventive Procedure
C15180
Pain Therapy
Pain, Pain Management
Analgesia
Pain Management
owl:Class
Liver Function Test
C74954
Laboratory Procedure
Liver Function Test
LFT
Chemistry Test
C0023901
Liver Function Test
The quantitative measurement of liver enzymes in the blood, which is useful in assessing the functional state of a patient's liver. Liver function tests include the measurement of albumin, alanine transaminase, aspartate transaminase, alkaline phosphatase, bilirubin, and gamma glutamyl transferase.
Liver Function Test
Subsecond Spiral CT
owl:Class
Spiral CT
Subsecond Spiral CT
C19912
Subsecond Spiral CT
Diagnostic Procedure
A type of computer tomography that allows a full rotation of the X-ray tube around the patient in less than 1 second.
CL009738
Subsecond Spiral CT
Total Thyroxine Measurement
CDISC SDTM Laboratory Test Terminology by Name
CDISC
CDISC SEND Terminology
T4
Total Thyroxine Measurement
Hormone Measurement
CDISC SDTM Laboratory Test Terminology by Code
<def-source>CDISC</def-source><def-definition>A measurement of the total (free and bound) thyroxine in a biological specimen.</def-definition>
Laboratory Procedure
Clinical Data Interchange Standards Consortium Terminology
Total Thyroxine Measurement
C74794
Total Thyroxine Measurement
CDISC SDTM Terminology
Newborn Screening
owl:Class
Thyroxine
C1281902
The determination of the amount of free and bound thyroxine present in a sample.
Laboratory Procedure
C78179
owl:Class
Hematology Test
C0034554
RAST
Radioallergosorbent Test
A type of blood test used to test for allergies.
Radioallergosorbent Test
Radioallergosorbent Test
Radioallergosorbent Test
C80406
Stress Electrocardiography
Electrocardiography
owl:Class
Stress Electrocardiography
Stress Test
Stress Electrocardiography
Diagnostic Procedure
A recording of cardiac electrical activity during stress or exercise.
Stress Electrocardiography
Dose Modification
Agent Dose Increased
Functional Concept
Agent Dose Increased
C70890
Agent Dose Increased
CL375929
Agent Dose Increased
owl:Class
An area of interest or recreational activity that someone pursues outside their occupational duties.
C0019826
Hobby
Behavior
Hobby
C73426
Daily or Recreational Activity
Hobby
Hobby
owl:Class
C80181
owl:Class
Free Non-esterified Fatty Acids Measurement
Free Non-esterified Fatty Acids Measurement
Free Non-esterified Fatty Acids Measurement
The determination of the amount of free non-esterified fatty acids present in a sample.
Laboratory Procedure
Fatty Acid Measurement
Free Non-esterified Fatty Acids Measurement
Regression analysis provides a "best-fit" mathematical equation for the relationship between the dependent variable (response) and independent variable(s) (covariates). There are two major classes of regression - parametric and non-parametric. Parametric regression requires choice of the regression equation with one or a greater number of unknown parameters. Linear regression, in which a linear relationship between the dependent variable and independent variables is posited, is an example. The aim of parametric regression is to find the values of these parameters which provide the best fit to the data. The number of parameters is usually much smaller than the number of data points. In contrast, the non-parametric regression requires no such a choice of the regression equation.
Regression Method
Quantitative Concept
Statistical Test
Regression Method
Regression Method
Regression Method
C0034980
owl:Class
Regression Analysis
C53237
Fluorescence Activated Cell Sorting
Fractionation, Fluorescence Activated Cell Sorting
owl:Class
Laboratory Procedure
Fluorescence Activated Cell Sorting
Fluorescence Activated Cell Sorting
C0079366
C17353
Selection and deposition of individual cells of a particular phenotype from a mixed population into a separate tube or tissue culture plate by the use of a fluorescence-activated cell sorter (FACS) and fluorescently-labeled antibodies specific for surface molecules on the cells to be sorted.
Fluorescence Activated Cell Sorting
Cell Sorting
FACS
Diagnostic Procedure
Biopsy of Pharyngeal Tonsil
Biopsy of Pharyngeal Tonsil
Removal of tissue from the pharyngeal tonsil for microscopic examination.
Biopsy of Adenoids
owl:Class
Biopsy
CL355000
C51487
Procedure_Has_Partially_Excised_Anatomy only 'Pharyngeal Tonsil'
Biopsy of Pharyngeal Tonsil
Biopsy of Pharyngeal Tonsil
Diagnostic Procedure
Excisional Biopsy
owl:Class
Excisional Biopsy
<def-source>NCI-GLOSS</def-source><def-definition>(ek-SI-zhun-al BY-op-see) A surgical procedure in which an entire lump or suspicious area is removed for diagnosis. The tissue is then examined under a microscope.</def-definition>
excisional biopsy
Biopsy
Excisional Biopsy
C0184921
Excision
A surgical procedure in which an entire lesion is removed for microscopic examination.
Excisional Biopsy
Procedure_Has_Partially_Excised_Anatomy only Organ
C15385
CL384616
Drug Class Measurement
CNS Affecting Drug Measurement
CNS Affecting Drug Measurement
Laboratory Procedure
owl:Class
CNS Affecting Drug Measurement
The determination of the amount of any drug that affects the central nervous system (CNS) present in a sample.
C75340
CNS Affecting Drug Measurement
Synaptophysin and Hematoxylin Staining Method
Synaptophysin Immunohistochemistry counterstained with Hematoxylin.
CL101869
Laboratory Procedure
Special Histology Staining Method
Synaptophysin and Hematoxylin Staining Method
Samples counterstained with hematoxylin following Synaptophysin staining.
Synaptophysin
Synaptophysin and Hematoxylin Staining Method
Synaptophysin and Hematoxylin
Synaptophysin and Hematoxylin Staining Method
C28415
owl:Class
Synaptophysin and Hematoxylin Staining Method
The addition of energy to a system, thereby transferring it from its ground state to an excited state.
Excitation
C70662
C0549255
Excitation
Activity
Action
Excite
Excited
Excitation
Excitation
owl:Class
YAC-Based STS-Content Mapping
YAC-Based STS-Content Mapping
YAC-Based STS-Content Mapping
Molecular Biology Research Technique
C19654
Clone-Based Physical Mapping
owl:Class
YAC-Based STS-Content Mapping
YAC based content mapping is a clone-based physical genome mapping strategy. Content mapping is done by ordering sequence tagged sites (STS), regions of the genome which can be uniquely identified, and YAC (Yeast Artificial Chromosome) clone ends along the chromosome, based on the STS content of each clone, for constructing a composite map that represents the linear order and position of mapping landmarks along the genome.
Laboratory Procedure
CL008169
Komogorov-Smirnov Test
Komogorov-Smirnov Test
Komogorov-Smirnov Test
Quantitative Concept
Komogorov-Smirnov Test
Non-Parametric Test
CL356685
C53250
Either the Kolmogorov-Smirnov one-sample test, a goodness-of-fit test, that tests whether an observed dataset is consistent with an hypothesized theoretical distribution or the Kolmogorov-Smirnov two-sample test, a test of the null hypothesis that two independent samples have been drawn from the same population (or from populations with the same distribution).
owl:Class
Hydration Therapy
Hydration Therapy
Physiological Support
Therapeutic or Preventive Procedure
Hydration Therapy
Hydration Therapy
CL371173
C66896
owl:Class
CL378151
Simple Random Sampling with Replacement
owl:Class
Simple Random Sampling with Replacement
C71495
Simple Random Sampling
Simple Random Sampling with Replacement
Simple Random Sampling with Replacement
Quantitative Concept
ISH
in situ Hybridization Staining Method
owl:Class
In Situ Hybridization Staining Method
Special Histology Staining Method
in situ Hybridization Staining Method
in situ Hybridization Staining Method
in situ Hybridization Staining Method
Laboratory Procedure
CL100941
In Situ Hybridization Staining Method
In Situ Hybridization
C23022
In Situ Hybridization staining is an immunohistochemistry staining procedure which allows the demonstration of specific nucleic acid sequences (genes) in their cellular environment. The DNA sequence in the host cell is detected by hybridization with a biotin-labeled cDNA probe. Used for detecting protein and gene expression, determining tissue specificity, and localizing genes and proteins within tissue samples.
Individual Behavior
owl:Class
The act of sexual procreation between a man and a woman; the man's penis is inserted into the woman's vagina and excited until orgasm and ejaculation occur.
C0009253
Sexual Intercourse
Sexual Intercourse
Intercourse
C72881
Sexual Intercourse
Personal Behavior
Sexual Intercourse
Suck
owl:Class
Suck
C65117
Activity
C1638402
Suck
Instruction Imperative
Suck
Genetic Annotation Initiative
C15954
CL003371
CGAP-GAI
Genetic Annotation Initiative
Genetic Annotation Initiative (GAI)
GAI
NCI initiate to explore, develop and then apply technology for identification and characterization of genes important in cancer. Based on gene discovery program in CGAP, the GAI is currently exploring the application of multiple technological approaches to searching the 3'UTR of genes for sequence variation. Once identified and confirmed, these variants will be put into public databases maintained by NCIBI's dbSNP and CGAP web resources. See also Cancer Genome Anatomy Project.
Research Activity
CGAP Genetic Annotation Initiative
Cancer Genome Anatomy Project
owl:Class
Genetic Annotation Initiative
Genetic Annotation Initiative
CL370146
Diagnostic Lymphadenectomy
owl:Class
Diagnostic Procedure
Lymphadenectomy
Diagnostic Lymphadenectomy
Diagnostic Surgical Procedure
Diagnostic Lymphadenectomy
Diagnostic Lymphadenectomy
C64983
Phase III Trial
Phase III Trial
phase III trial
Clinical Trials, Phase III
Research Activity
<def-source>CDISC</def-source><def-definition>Phase 3. Studies are expanded controlled and uncontrolled trials. They are performed after preliminary evidence suggesting effectiveness of the drug has been obtained, and are intended to gather the additional information about effectiveness and safety that is needed to confirm efficacy and evaluate the overall benefit-risk relationship of the drug and to provide an adequate basis for physician labeling. NOTE: Phase 3 studies usually include from several hundred to several thousand subjects. [After FDA CDER Handbook, ICH E8] (CDISC glossary)</def-definition>
owl:Class
Phase III Trial
Phase III Study
Phase 3 Study
CDISC SDTM Trial Phase Terminology
Clinical Data Interchange Standards Consortium Terminology
Phase III Trials
Phase III Clinical Trial
A clinical research protocol designed to investigate the efficacy of the biomedical or behavioral intervention in large groups of human subjects (from several hundred to several thousand), to confirm efficacy, to monitor adverse reactions to the new medication or treatment regimen with respect to long-term use and by comparing the intervention to other standard or experimental interventions as well as to a placebo.
<def-source>NCI-GLOSS</def-source><def-definition>A study to compare the results of people taking a new treatment with the results of people taking the standard treatment (for example, which group has better survival rates or fewer side effects). In most cases, studies move into phase III only after a treatment seems to work in phases I and II. Phase III trials may include hundreds of people.</def-definition>
C15602
CDISC SDTM Terminology
C0282461
CDISC
Clinical Study by Phase
Phase III Trial
3
Trial Phase 3
Phase III Protocol
DNA Resequencing
DNA Resequencing
DNA Resequencing
owl:Class
CL331946
Resequencing
C41254
A specific application of gene sequencing that precisely determines the sequence of bases in DNA. Resequencing is used to identify single nucleotide polymorphisms (SNPs).
DNA Resequencing
Laboratory Procedure
Molecular Biology Research Technique
Nucleic Acid Sequencing
Erythrocyte Sedimentation Rate Measurement
ESR
CDISC SDTM Laboratory Test Terminology by Name
A quantitative measurement of the distance that red blood cells travel in one hour in a sample of unclotted blood.
<def-source>CDISC</def-source><def-definition>The distance (e.g. millimeters) that red blood cells settle in unclotted blood over a specified unit of time (e.g. one hour).</def-definition>
Erythrocyte Sedimentation Rate Measurement
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Code
C74611
CDISC
CDISC SEND Terminology
owl:Class
Clinical Data Interchange Standards Consortium Terminology
Erythrocyte Sedimentation Rate Measurement
Blood Chemistry Measurement
CDISC SDTM Terminology
Erythrocyte Sedimentation Rate
Erythrocyte Sedimentation Rate Measurement
C1176468
CL375928
Functional Concept
Agent Dose Decreased
Agent Dose Decreased
Agent Dose Decreased
C70889
Agent Dose Decreased
Dose Modification
owl:Class
LED therapy
LED Therapy
LED Therapy
CL371757
C67341
The use of LED light or radiation for treatment of various conditions including skin treatments and chemotherapy.
LED Therapy
owl:Class
<def-source>NCI-GLOSS</def-source><def-definition>Treatment with drugs that become active and may kill cancer cells when exposed to light. LED therapy is a type of photodynamic therapy, which uses a special type of light to activate the drug.</def-definition>
Therapeutic Procedure
LED Therapy
Therapeutic or Preventive Procedure
Light-Emitting Diode Therapy
Colon Imaging Study
Image Study
Colon Imaging Study
Diagnostic Procedure
Colon Imaging Study
owl:Class
CL365547
C62687
Colon Imaging Study
Doppler Ultrasound
Doppler Ultrasound
Diagnostic Procedure
Diagnostic imaging that uses sound waves (ultrasound) applying the Doppler effect, with frequency-shifted ultrasound reflections produced by moving targets (usually red blood cells) in the bloodstream along the ultrasound axis in direct proportion to the velocity of movement of the targets, to determine both direction and velocity of blood flow.
Doppler Ultrasound
Ultrasound Imaging
owl:Class
C62781
Doppler Ultrasound
C0162481
Mosteller Body Surface Area Formula
owl:Class
Mosteller BSA Formula
CL374479
Mosteller Body Surface Area Formula
Mosteller Body Surface Area Formula
C68646
Mosteller Body Surface Area Formula
Occupational Activity
Body Surface Area Formula
The formula to calculate body surface area as described by RD Mosteller. It is mathematically defined as: BSA (m^2) = ([Height(cm) x Weight(kg)]/3600)^0.5; e.g. BSA = SQRT((cm x kg)/3600)
Mosteller
Supplementation
Therapeutic or Preventive Procedure
<def-source>NCI-GLOSS</def-source><def-definition>Adding nutrients to the diet.</def-definition>
supplementation
C15425
C0242297
Supplementation
Supplementation
Supplementation
owl:Class
Nutritional Support
CL354717
Mastoidectomy
Total or partial excision of the mastoid process.
Mastoidectomy
C51751
Mastoidectomy
Therapeutic or Preventive Procedure
Procedure_Has_Excised_Anatomy only 'Mastoid Process'
Head and Neck Surgery
owl:Class
Mastoidectomy
Ultrasound Therapy
Therapeutic or Preventive Procedure
Ultrasound Therapy
Ultrasound Therapy
<def-source>NCI-GLOSS</def-source><def-definition>A form of therapy being studied as an anticancer treatment. Intensified ultrasound energy can be directed at cancer cells to heat them and kill them.</def-definition>
owl:Class
Ultrasound Therapy
C0041620
Hyperthermia Treatment
ultrasound energy
C28003
Bacteriolytic Therapy
owl:Class
Bacteriolytic Therapy
Biological Therapy
Therapy that uses anaerobic bacterium, particularly Clostridium novyi-NT, to kill cancer cells within the hypoxic regions of tumors.
Therapeutic or Preventive Procedure
CL365519
Bacteriolytic Therapy
Bacteriolytic Therapy
C62711
owl:Class
Assessment of Gonadal Function
Diagnostic Procedure
Diagnostic Procedure
C17869
Assessment of Gonadal Function
Testing to determining the function of testes and ovaries, frequently performed as part of a fertility assessment.
Assessment of Gonadal Function
Assessment of Gonadal Function
CL030005
Mouse Cancer Genome Anatomy Project
A component of CGAP.
C15976
Intellectual Product
Mouse Tumor Gene Index
Mouse Tumor Gene Index
Mouse Tumor Gene Index
Research Activity
Mouse Tumor Gene Index
owl:Class
CL003771
Systemic Therapy
C15698
<def-source>NCI-GLOSS</def-source><def-definition>(sis-TEM-ik THER-a-pee) Treatment using substances that travel through the bloodstream, reaching and affecting cells all over the body.</def-definition>
Systemic Therapy
CL031872
systemic therapy
Therapeutic Procedure
owl:Class
Systemic Therapy
Systemic Therapy
Therapeutic or Preventive Procedure
CL000686
C15832
owl:Class
Patient Oriented Research
Research Activity
Patient Oriented Research
Patient Oriented Research
Patient Oriented Research
Human Subject Research
Studies of living individuals or groups of subjects (such as families, communities, or populations defined geographically or demographically), or material of human origin (such as tissues, specimens, and cognitive phenomena, etc.), for understanding of their physiologic and pathophysiologic characteristics, mechanisms of human diseases and development of approaches to diseases treatment and prevention. Includes the laboratory-based development of new forms of technology, studies of health-related professions, institutions, and systems, excludes disease-oriented studies of material, obtained from patients who were unknown to investigators.
<def-definition>A relative measurement (ratio or percentage) of the lactate dehydrogenase isoenzyme 4 to total lactate dehydrogenase in a biological specimen.</def-definition><def-source>CDISC</def-source>
C79454
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Terminology
LDH Isoenzyme 4 to LDH Ratio Measurement
The determination of the ratio of LDH isoenzyme 4 compared to total LDH present in a sample. The measurement may be expressed as a ratio or percentage.
Clinical Data Interchange Standards Consortium Terminology
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Code
LDH4LDH
LDH Isoenzyme 4 to LDH Ratio Measurement
Protein or Enzyme Type Measurement
CDISC SEND Terminology
LDH Isoenzyme 4/LDH
LDH Isoenzyme 4 to LDH Ratio Measurement
LDH Isoenzyme 4 to LDH Ratio Measurement
owl:Class
Nude Mouse Assay
Basic Science Research
Nude Mouse Assay
Nude Mouse Assay
Research Activity
Any bioassay using a nude mouse.
C19351
Nude Mouse Assay
CL003879
owl:Class
Patient-Centered Outcomes
Patient-Focused Outcomes
C16075
Traditional methods for evaluating treatment outcome focus on disease state. Patient-Focused Outcomes places a greater emphasis on quality of life issues.
Research Activity
Patient-Focused Outcomes
Patient-Focused Outcomes
CL008240
Patient-Focused Outcomes
owl:Class
Outcomes Research
Patient Oriented Research
Atomic Resolution X-Ray Crystallography
Laboratory Procedure
Atomic Resolution X-Ray Crystallography
A method of crystallography for the elucidation of protein structure with ultra-high resolution (&lt; 1.2 Angstrom). X-rays are passed through crystals and the subsequent diffraction pattern is analyzed. The position of the atoms can be reconstructed using computerized analysis of the diffraction pattern. The atomic positions are accurately defined and fine details in the electron density become visible, which reveal small but significant structural changes.
Atomic Resolution X-Ray Crystallography
owl:Class
C19588
CL005625
Atomic Resolution X-Ray Crystallography
X-Ray Crystallography
C64236
RMA2 Background Correction Method
Background Correction Method
RMA2 Background Correction Method
Perform a modified version of RMA background correction. Defined in the documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html.
Activity
CL369342
RMA2 Background Correction Method
owl:Class
RMA2 Background Correction Method
C79433
Clinical Data Interchange Standards Consortium Terminology
Alpha Glutathione-S-Transferase Measurement
CDISC SDTM Terminology
<def-definition>A measurement of the alpha form of glutathione S-transferase in a biological specimen.</def-definition><def-source>CDISC</def-source>
Alpha Glutathione-S-Transferase
Laboratory Procedure
owl:Class
Alpha Glutathione-S-Transferase Measurement
Alpha Glutathione-S-Transferase Measurement
GSTAL
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Laboratory Test Terminology by Code
Protein or Enzyme Type Measurement
Alpha Glutathione-S-Transferase Measurement
The determination of the amount of alpha glutathione-s-transferase present in a sample.
Clinical Data Interchange Standards Consortium Terminology
owl:Class
C0523565
CDISC SDTM Laboratory Test Terminology by Code
Laboratory Procedure
The determination of the amount of cholecystokinin hormone present in a sample.
Cholecystokinin Measurement
Cholecystokinin
CDISC SDTM Terminology
CCK
Cholecystokinin Measurement
CDISC SDTM Laboratory Test Terminology by Name
Cholecystokinin Measurement
Hormone Measurement
<def-definition>A measurement of the cholecystokinin hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
C74850
Pancreozymin
Cholecystokinin Measurement
CDISC SEND Terminology
Protein Expression Analysis
CL366423
C63480
Laboratory Procedure
Protein Analysis
Protein Expression Analysis
owl:Class
Protein Expression Analysis
Protein Expression Analysis
owl:Class
Refers to a step in the process of in vitro fertilization (IVF) whereby one or several embryos are removed from an embryo culture and placed into the uterus of the female with the intent to establish a pregnancy.
Embryo Transfer
Embryo Transfer
C16541
Therapeutic or Preventive Procedure
Embryo Transfer
C0013938
Reproductive Technique
Embryo Transfer
div.
Activity
Divide
Divide
CL370155
Instruction Imperative
Divide
C64659
owl:Class
Divide
C74846
Angiotensinogen
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Terminology
Angiotensinogen Measurement
owl:Class
Laboratory Procedure
CDISC SEND Terminology
Angiotensin Precursor
Clinical Data Interchange Standards Consortium Terminology
Angiotensinogen Measurement
CDISC SDTM Laboratory Test Terminology by Code
<def-definition>A measurement of the angiotensinogen hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
C0523500
Angiotensinogen Measurement
Hormone Measurement
ANGTNSGN
Angiotensinogen Measurement
The determination of the amount of angiotensinogen hormone present in a sample.
Cardiac Diagnostic Procedure
Cardiac Event Monitor
Diagnostic Procedure
Cardiac Event Monitor
C80401
owl:Class
A medical device used to record the electrical activity of the heart. Often, the wearer will input a signal which is used as an event marker when they feel symptoms such as tachycardia, as the device continuously records cardiac activity.
Cardiac Event Monitor
Cardiac Event Monitor
Spiral CT
Dynamic Spiral CT
owl:Class
A type of computed tomography in which the patient is moved through the scanner continuously rather than in increments, so that the path of the beam through the patient is a continuous spiral.
Diagnostic Procedure
CL009739
C19913
Dynamic Spiral CT
Dynamic Spiral CT
Dynamic Spiral CT
A training technique in which various bodily functions, such as heart rate, skin temperature, muscle tension, and brain activity are monitored so that people can learn to control them voluntarily so as to improve their health and physical performance.
Mind-Body Intervention Procedure
Mental Process
Biofeedback
Biofeedback
Biofeedback
Biofeedback
owl:Class
biofeedback
C0005491
C15186
owl:Class
An x-ray examination of the esophagus, stomach and first part of the small intestine following coating with barium solution via ingestion.
Upper Gastrointestinal Series
Diagnostic Procedure
Upper Gastrointestinal Series
C17639
Barium-Swallow X-ray
C0203057
upper GI series
Upper GI
Upper Gastrointestinal Series
<def-source>NCI-GLOSS</def-source><def-definition>A series of x-rays of the upper digestive (gastrointestinal, or GI) system that are taken after a person drinks a barium solution, which outlines the digestive organs on the x-rays.</def-definition>
Radiography
Upper GI Series
Upper Gastrointestinal Series
Upper Gastrointestinal Tract Radiography
Blocking
Action
Blocked
owl:Class
Blockade
Interrupt the normal function of; hinder or prevent the progress or accomplishment of; stop from happening or developing; interfere with or prevent the reception of signals; impede the movement of.
C61286
Block
Block
Block
Activity
Block
C0332206
Constant Normalization
Bioconductor caAffy Constant Normalization
A method to scale Affymetrix arrays, as defined in documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html
Activity
CL369463
Bioconductor caAffy Constant Normalization
Bioconductor caAffy Constant Normalization
C63930
Bioconductor caAffy Constant Normalization
owl:Class
STOMCY
Erythrocyte Count
CDISC SDTM Laboratory Test Terminology by Code
C74708
Stomatocyte Count
CDISC SDTM Terminology
Laboratory Procedure
Stomatocyte Count
CDISC
CDISC SDTM Laboratory Test Terminology by Name
Stomatocyte Count
owl:Class
The determination of the number of stomatocytes present in a sample.
CL384748
CDISC SEND Terminology
Stomatocytes
Stomatocyte Count
Clinical Data Interchange Standards Consortium Terminology
<def-source>CDISC</def-source><def-definition>A measurement of the stomatocytes (red blood cells with an oval or rectangular area of central pallor, producing the appearance of a cell mouth) in a biological specimen.</def-definition>
Quantitative Concept
CL356712
Parametric Test
C53244
Pearson Correlation Test
Correlation Test
Pearson Correlation Test
Pearson Correlation
Pearson Correlation Test
owl:Class
Pearson Correlation Test
CDISC SDTM Laboratory Test Terminology by Code
The determination of the number of elliptocytes in a blood sample.
owl:Class
CDISC SDTM Laboratory Test Terminology by Name
Ovalocytes
Elliptocyte Count
Elliptocyte Count
<def-definition>A measurement of the elliptically shaped erythrocytes in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SEND Terminology
C64549
Clinical Data Interchange Standards Consortium Terminology
CL370574
Elliptocytes
CDISC SDTM Terminology
CDISC
Erythrocyte Count
Elliptocyte Count
Laboratory Procedure
Elliptocyte Count
ELLIPCY
CDISC SDTM Trial Summary Parameter Terminology by Name
Trial Indication Type
Trial Indication Type
owl:Class
Trial Indication Type
Clinical Study Intent
CDISC SDTM Trial Summary Parameter Terminology by Code
The name of a code list that contains terms to define the type of trial, e.g. cure or prevention.
CDISC SDTM Terminology
CDISC
C1710474
TINDTP
Study Intent
Research Activity
<def-source>CDISC</def-source><def-definition>The name of a code list that contains terms to define the type of trial, e.g. cure or prevention. (NCI)</def-definition>
Trial Indication Type
C49652
Clinical Trial
Clinical Study by Intent
Clinical Data Interchange Standards Consortium Terminology
Free T4
Free Thyroxine Measurement
Laboratory Procedure
Free Thyroxine Measurement
Thyroxine, Free
Free Thyroxine Measurement
The determination of the amount of free thyroxine present in a sample.
Free Thyroxine Measurement
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Name
CDISC
CDISC SEND Terminology
C74786
CDISC SDTM Laboratory Test Terminology by Code
Hormone Measurement
C0202225
owl:Class
CDISC SDTM Terminology
T4FR
<def-source>CDISC</def-source><def-definition>A measurement of the free thyroxine in a biological specimen.</def-definition>
owl:Class
Cancer Burden
A measure of the incidence of cancer within the population and an estimate of the financial, emotional, or social impact it creates. The burden of disease is not borne equally by all population groups in the United State.
Population-Based Statistic
CL008187
Cancer Burden
Quantitative Concept
C16064
Cancer Burden
National Cancer Burden
Cancer Burden
Extensive Radiation
Extensive Radiation
Extensive Radiation
CL027517
Cancer therapy using ionizing radiation to a significant (>50%) portion of the body, e.g. craniospinal, total body irradiation, or pelvic radiation.
Extensive Radiation
Radiation Therapy
Therapeutic or Preventive Procedure
owl:Class
C16230
Pyridinoline Measurement
Pyridinoline Measurement
owl:Class
The determination of the amount of pyridinoline present in a sample.
Pyridinoline Measurement
Laboratory Procedure
Chemistry Test
C80211
Pyridinoline Measurement
Statistical Confidence
The statistical calculation of the percentage likelihood for a given set of data to have a given statistical value.
Statistical Confidence
CL353064
Confidence
owl:Class
Statistical Confidence
Statistical Confidence
Qualitative Concept
C49020
Statistical Technique
Haycock Body Surface Area Formula
Haycock BSA Formula
Body Surface Area Formula
Haycock Body Surface Area Formula
CL374456
C68648
The formula to calculate body surface area as described by D and EF DuBois D. It is mathematically defined as: BSA (m^2) = 0.024265 x [Height(cm)^0.3964] x [Weight(kg)^0.5378]
owl:Class
Haycock Body Surface Area Formula
Haycock
Occupational Activity
Haycock Body Surface Area Formula
CDISC SDTM Laboratory Test Terminology by Name
Interleukin 10 Measurement
Interleukin 10 Measurement
CL384287
CDISC SDTM Laboratory Test Terminology by Code
Interleukin 10 Measurement
Clinical Data Interchange Standards Consortium Terminology
Interleukin 10 Measurement
Laboratory Procedure
CDISC SDTM Terminology
Interleukin 10
Cytokine Measurement
The determination of the amount of interleukin 10 present in a sample.
<def-definition>A measurement of the interleukin 10 in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SEND Terminology
owl:Class
C74806
INTLK10
Ectocervical Biopsy
Ectocervical Biopsy
Exocervical Biopsy
Diagnostic Procedure
Procedure_Has_Partially_Excised_Anatomy only Ectocervix
CL354528
Removal of tissue from the ectocervix for microscopic examination.
Cervical Biopsy
Ectocervical Biopsy
Ectocervical Biopsy
owl:Class
C51630
C18091
Gel Electrophoresis
Gel Electrophoresis
Electrophoresis
C0596607
owl:Class
Laboratory Procedure
Gel electrophoresis is a method of separating large molecules (such as DNA fragments or proteins) from a mixture of similar molecules by electrophoretic filtration through a gelatinous matrix. Subject to an electric field, each molecule in the sample mixture migrates through the matrix at a different rate, depending mainly on electrical charge and size, resulting in spatial separation within the matrix of each molecular species in the sample mixture. Agarose and acrylamide in a cylindrical tube or slab gel are commonly used media for electrophoresis of proteins and nucleic acids.
Molecular Biology Research Technique
Molecular Analysis
Gel Electrophoresis
Gel Electrophoresis
Pentobarbital Measurement
Laboratory Procedure
Barbiturate Drug Class Measurement
The determination of the amount of pentobarbital present in a sample.
C0202444
Pentobarbital Measurement
owl:Class
Pentobarbital Measurement
Pentobarbital Measurement
C75367
Column Chromatography
Affinity Chromatography
C0008551
A chromatographic separation technique based on the ability of proteins to bind specific ligands reversibly.
C16432
owl:Class
Affinity Chromatography
Affinity Chromatography
Laboratory Procedure
Affinity Chromatography
CL024187
Cancer Research
Cancer Research
Cancer Research
Research Activity
Cancer Research Programs
Cancer Research
Cancer Research Project
owl:Class
Research Activity
C16199
High Vegetable Diet
Dietary Practices
C20048
High Vegetable Diet
High consumption of vegetables and related micronutrients; exerts a moderate protective effect on the risk of developing breast cancer. (from Medscape)
CL014762
Individual Behavior
High Vegetable Diet
High Vegetable Diet
owl:Class
Vanilmandelic Acid
<def-definition>A measurement of the vanillyl mandelic acid metabolite in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Terminology
owl:Class
Clinical Data Interchange Standards Consortium Terminology
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Code
VMA
CL384436
Hormone Measurement
Vanillyl Mandelic Acid Measurement
Vanillyl Mandelic Acid Measurement
C74875
CDISC SDTM Laboratory Test Terminology by Name
Vanillyl Mandelic Acid Measurement
CDISC SEND Terminology
The determination of the amount of vanillyl mandelic acid metabolite present in a sample.
Vanillyl Mandelic Acid Measurement
Vanillyl Mandelic Acid
Prior Androgen Therapy
Prior Androgen Therapy
Prior Hormone Therapy
Clinical Attribute
Prior Androgen Therapy
C15504
owl:Class
Prior Androgen Therapy
CL029672
Analysis
C0002778
Activity
owl:Class
Analysis
Analyzed
Examination and interpretation; the process of identifying an issue to be understood and addressed, modelling the issue, investigating the model results, interpreting the results, and possibly making a recommendation. The concept also refers to the examination and study of a whole in terms of the parts composing it.
Analysis
Analytical
Action
Analysis
C25391
Phase I Trial
CDISC SDTM Terminology
C0920321
<def-source>NCI-GLOSS</def-source><def-definition>The first step in testing a new treatment in humans. These studies test the best way to give a new treatment (for example, by mouth, intravenous infusion, or injection) and the best dose. The dose is usually increased a little at a time in order to find the highest dose that does not cause harmful side effects. Because little is known about the possible risks and benefits of the treatments being tested, phase I trials usually include only a small number of patients who have not been helped by other treatments.</def-definition>
Phase I Clinical Trials
A clinical research protocol designed to test a new biomedical intervention in a small group of people for the first time. A Phase I trial can be to establish the toxicity of a new treatment with escalating intensity of the treatment administered and/or to determine the side effects of a new treatment for a particular indication in subjects.
Phase I Trial
Phase 1 Study
Clinical Study by Phase
CDISC SDTM Trial Phase Terminology
Clinical Trials, Phase I
Clinical Data Interchange Standards Consortium Terminology
Phase I Protocol
Trial Phase 1
Early-Stage Clinical Trials
1
CDISC
C15600
Phase I Trial
Phase I Study
Research Activity
<def-source>CDISC</def-source><def-definition>The initial introduction of an investigational new drug into humans. Phase 1 studies are typically closely monitored and may be conducted in patients or normal volunteer subjects. NOTE: These studies are designed to determine the metabolism and pharmacologic actions of the drug in humans, the side effects associated with increasing doses, and, if possible, to gain early evidence on effectiveness. During Phase 1, sufficient information about the drug's pharmacokinetics and pharmacological effects should be obtained to permit the design of well-controlled, scientifically valid, Phase 2 studies. The total number of subjects and patients included in Phase I studies varies with the drug, but is generally in the range of 20 to 80. Phase 1 studies also include studies of drug metabolism, structure-activity relationships, and mechanism of action in humans, as well as studies in which investigational drugs are used as research tools to explore biological phenomena or disease processes. [After FDA CDER Handbook, ICH E8] (CDISC glossary)</def-definition>
Phase I Trial
phase I trial
owl:Class
Radiation Therapy
Tomotherapy
Tomotherapy
CL365464
owl:Class
Tomotherapy
Tomotherapy
C62731
Therapeutic or Preventive Procedure
Biochemistry, Manometry
<def-source>MSH2001</def-source><def-definition>Measurement of the pressure or tension of liquids or gases. (From Dorland, 27th ed)</def-definition>
Manometry
C0024751
owl:Class
Laboratory Procedure
C16820
Manometry
Measurement of the pressure or tension of liquids or gases.
Manometry
Manometry
Physical Chemical Technique
C71292
Transmission
Action
owl:Class
Transmittal
Activity
Transmission
The act of sending a message; causing a message to be transmitted.
Transmission
CL377744
Transmitted
Transmission
CL008675
Educational Activity
Cancer Genetics Education Program
owl:Class
Health Education
C19719
Cancer Genetics Education Program
Cancer Genetics Education Program
Cancer Genetics Education Program
CDISC SDTM Terminology
CDISC SEND Terminology
May-Hegglin Anomaly Measurement
Laboratory Procedure
MAYHEG
Clinical Data Interchange Standards Consortium Terminology
May-Hegglin Anomaly Measurement
CDISC SDTM Laboratory Test Terminology by Name
<def-definition>A measurement of the May-Hegglin anomaly in a blood sample. This anomaly is characterized by large, misshapen platelets and the presence of Dohle bodies in leukocytes.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Laboratory Test Terminology by Code
Hematology Test
The determination of the amount of May-Hegglin anomaly present in a blood sample.
May-Hegglin Anomaly
May-Hegglin Anomaly Measurement
May-Hegglin Anomaly Measurement
owl:Class
CL384759
CDISC
C74614
C15485
CL029468
Therapeutic or Preventive Procedure
Neurotoxicity Attenuation
owl:Class
Toxicity Attenuation
Neurotoxicity Attenuation
Neurotoxicity Attenuation
Neurotoxicity Attenuation
Autologous Hematopoietic Stem Cell Transplantation
Hematopoietic Stem Cell Transplantation
Autologous Hematopoietic Stem Cell Transplantation
CL004894
C16039
Autologous Hematopoietic Stem Cell Transplantation
Therapeutic or Preventive Procedure
Autologous Stem Cell Transplantation
Stem cell transfer or transplantation in which the patient is his own donor.
Autologous Hematopoietic Stem Cell Transplantation
owl:Class
C80204
Protein or Enzyme Type Measurement
Prostatic Acid Phosphatase Measurement
owl:Class
Prostatic Acid Phosphatase Measurement
Prostatic Acid Phosphatase Measurement
Laboratory Procedure
The determination of the amount of prostatic acid phosphatase present in a sample.
Prostatic Acid Phosphatase Measurement
sigmoidoscopy
Therapeutic or Preventive Procedure
Sigmoidoscopy
owl:Class
Procedure_Has_Target_Anatomy only 'Sigmoid Colon'
Diagnostic Procedure
Proctosigmoidoscopy
Sigmoidoscopy
<def-source>NCI-GLOSS</def-source><def-definition>(sig-moid-OSS-ko-pee) Inspection of the lower colon using a thin, lighted tube called a sigmoidoscope. Samples of tissue or cells may be collected for examination under a microscope. Also called proctosigmoidoscopy.</def-definition>
Sigmoidoscopy
C0037075
proctosigmoidoscopy
Sigmoidoscopy
C17131
<def-source>NCI-GLOSS</def-source><def-definition>(PROK-toe-sig-moid-OSS-ko-pee) An examination of the rectum and the lower part of the colon using a thin, lighted tube called a sigmoidoscope.</def-definition>
Colonoscopy
Endoscopic examination of the luminal surface of the sigmoid colon.
Therapeutic or Preventive Procedure
The application of heat to appropriate painful areas to improve blood flow and function and to reduce pain. It can be applied though many methods, using convection, conduction, or radiation. Conduction uses hydrocollator, paraffin, or other similar methods. Convection uses immersion hydrotherapy, immersion, forced fluidotherapy, and radiant heat. Radiation uses laser.
Heat Therapy
Therapeutic Heat
C0150611
Therapeutic Heat
Therapeutic Heat
owl:Class
Pain Therapy
Therapeutic Heat
C21117
C29899
owl:Class
Male Gonadal Ridge Implantation
A technique for transplantation of stem cells, derived from embryonic gonadal ridge (embryonic germ cells), which are pluripotent and capable of self-renewal for long periods. The technique has a wide potential to cure diseases by repairing or replacing damaged cells and tissues as well as in gene therapy.
Surgical Procedure by Method
Therapeutic or Preventive Procedure
Male Gonadal Ridge Implantation
Male Gonadal Ridge Implantation
CL320069
Male Gonadal Ridge Implantation
<def-source>NCI-GLOSS</def-source><def-definition>Continuous hyperthermic peritoneal perfusion. A procedure that bathes the abdominal cavity in fluid that contains anticancer drugs. This fluid is warmer than body temperature. This procedure appears to kill cancer cells without harming normal cells.</def-definition>
C15732
Continuous Hyperthermic Peritoneal Perfusion
owl:Class
Therapeutic or Preventive Procedure
CL032078
Continuous Hyperthermic Peritoneal Perfusion
continuous hyperthermic peritoneal perfusion
CHPP
<def-source>NCI-GLOSS</def-source><def-definition>CHPP. A procedure that bathes the abdominal cavity in fluid that contains anticancer drugs. This fluid is warmer than body temperature. This procedure appears to kill cancer cells without harming normal cells.</def-definition>
Continuous Hyperthermic Peritoneal Perfusion
Hyperthermic Perfusion
Continuous Hyperthermic Peritoneal Perfusion
Peritoneal Perfusion
Educational Activity
<def-source>MSH2001</def-source><def-definition>The teaching or training of patients concerning their own health needs.</def-definition>
Patient Education
C16959
owl:Class
Patient Education
Health Education
Patient Education
C0030688
Patient Education
Extraordinary Opportunity: Imaging Technologies
C16091
Extraordinary Opportunity: Imaging Technologies
CL008666
owl:Class
Extraordinary Opportunity: Imaging Technologies
Goal: to develop a comprehensive imaging research program to fit the development of imaging technology with medical needs to create a system to evaluate new imaging technologies rapidly and effectively. (NCI Web)
Extraordinary Opportunity: Imaging Technologies
Research Activity
Extraordinary Opportunities for Investment
Extensive Radiation
Clinical Attribute
<def-source>NCI-GLOSS</def-source><def-definition>Radiation therapy to the mantle field, the spleen, the lymph nodes in the upper abdomen, and the lymph nodes in the pelvic area.</def-definition>
Total Nodal Irradiation
CL032289
Total Nodal Irradiation
Prior Extensive Radiation
C15748
total nodal irradiation
Total Nodal Irradiation
owl:Class
Total Nodal Irradiation
owl:Class
LYM
CDISC SDTM Laboratory Test Terminology by Code
CDISC
CDISC SDTM Laboratory Test Terminology by Name
Lymphocyte Count
CDISC SDTM Terminology
Clinical Data Interchange Standards Consortium Terminology
Lymphocytes
Lymphocyte Count
CDISC SEND Terminology
Leukocyte Count
<def-definition>A measurement of the lymphocytes per unit of a biological specimen.</def-definition><def-source>CDISC</def-source>
Lymphocyte Count
Laboratory Procedure
The determination of the number of lymphocytes in a blood sample.
Lymphocyte Count
CL354678
C51949
owl:Class
Myelography
<def-source>MSH2001</def-source><def-definition>X-ray visualization of the spinal cord following injection of contrast medium into the spinal arachnoid space.</def-definition>
C0026995
Myelography
C20175
The radiographic examination of the spinal cord and nerve roots following the injection of a contrast medium into the spinal subarachnoid space. The X-rays taken may highlight conditions such as spinal tumors, spinal cord swelling and herniated discs.
Diagnostic Procedure
Myelography
Radiography
Myelography
Snowball Sampling
Quantitative Concept
Nonrandom Sampling
Snowball Sampling
C71514
owl:Class
Snowball Sampling
Snowball Sampling
CL378153
Laboratory Procedure
C19575
Random Peptide Synthesis
Random Peptide Synthesis
owl:Class
Generation of peptide libraries by random incorporation of all 20 amino acids.
Random Peptide Synthesis
Peptide Synthesis
CL004883
Random Peptide Synthesis
C51593
Procedure_Has_Excised_Anatomy only 'Parathyroid Gland'
owl:Class
Parathyroidectomy
Parathyroidectomy
Parathyroidectomy
Therapeutic or Preventive Procedure
Parathyroidectomy
CL354135
Head and Neck Surgery
Surgery to remove part or all of the parathyroid gland (s)
Laboratory Procedure
Frozen Section Diagnosis
C49338
Histologic Test
CL353411
Frozen Section Diagnosis
A method for rapid diagnosis that uses a frozen tissue sample rather than a chemically fixed sample.
Frozen Section
Diagnostic Procedure
Frozen Section Diagnosis
Frozen Section Diagnosis
owl:Class
Surveillance Methods
owl:Class
C19252
Surveillance Methods
CL003235
Surveillance Methods
Research Technique
Surveillance Methods
Health Care Activity
Methods used for potential identification of emerging disease threats and/or outbreaks so that public health personnel can take protective measures and minimize their impact on the health and economy of the world's population.
An arithmetic operation by which the product of two numbers is computed; the inverse of division.
Multiplication
Multiplication
owl:Class
Multiplication
Multiply
C65000
CL370477
Instruction Imperative
Action
Activity
Multiplication
Excision of the apical portion of a tooth root through an opening made in the overlying labial, buccal, lingual, or palatal alveolar bone.
owl:Class
Root Resection
Apicoectomy
Therapeutic or Preventive Procedure
C63716
Apicoectomy
C0003571
Dental Procedure
Apicoectomy
Apicoectomy
Cancer Prevention
C15780
Carcinogenesis Inhibition
CL000167
Suppression or prevention of the carcinogenic process/development of cancer.
Carcinogenesis Inhibition
Therapeutic or Preventive Procedure
owl:Class
Carcinogenesis, Inhibition
Carcinogenesis Inhibition
Carcinogenesis Inhibition
A laboratory procedure for the detection or identification of proteins or peptides that have been separated by gel electrophoresis and transferred onto nitrocellulose or other type of paper or nylon membrane. The proteins are then detected by reaction with enzymatically labeled or radiolabeled antibody probes.
Western Blotting
Blotting, Western
Protein Analysis
Western Blotting
Western Blotting
C0005863
owl:Class
Laboratory Procedure
Western Blotting
Western Blot
C16357
owl:Class
Fasting Blood Sugar Measurement
Fasting Blood Sugar Measurement
C80400
Laboratory Procedure
Blood Chemistry Measurement
Fasting Blood Sugar Measurement
Fasting Blood Sugar Measurement
Fasting Blood Sugar
A quantitative measurement of the amount of glucose present in a sample of blood, obtained from a source that has abstained from nutrition, typically at least 8 hours prior to the sample collection time.
FBS
CL004799
Cocrystallography
Cocrystallography
Cocrystallization
owl:Class
Crystallography
C19558
Laboratory Procedure
A protein crystallographic technique, which utilizes a unique quality filter to create crystal structures which show both the target protein fold and the part of the scaffold that binds to it. The technique is used for scaffold-based drug design.
Cocrystallography
Cocrystallography
Urine Sediment Analysis Measurement
CL384435
Urine Chemistry Measurement
owl:Class
Urine Sediment Analysis Measurement
Urine Sediment Analysis Measurement
The determination of the type and amount of particulate matter in a urine sample.
Urine Sediment Analysis Measurement
Laboratory Procedure
C74722
Heterophile Antibody Measurement
Immunology Test
Heterophile Antibody Measurement
Heterophile Antibody Measurement
Heterophile Antibody Measurement
C81984
owl:Class
The determination of the amount of heterophile antibodies present in a sample.
The determination of the amount of angiotensin converting enzyme present in a sample.
Protein or Enzyme Type Measurement
Angiotensin Converting Enzyme Measurement
owl:Class
Angiotensin Converting Enzyme Measurement
C80169
Angiotensin Converting Enzyme Measurement
Angiotensin Converting Enzyme Measurement
Laboratory Procedure
Summary (Mean) Heart Rate
CDISC SDTM ECG Test Terminology by Code
Quantitative Concept
HRMEAN
Mean Heart Rate
C62095
Mean Heart Rate
CDISC SDTM ECG Test Name Terminology
Clinical Data Interchange Standards Consortium Terminology
Mean Heart Rate
The average (mean) number of cycles of contraction and subsequent relaxation of the heart, usually expressed as beats per minute, obtained from a set of measurements of the heart rate.
CL364565
CDISC
Heart Rate
CDISC SDTM Terminology
owl:Class
<def-source>CDISC</def-source><def-definition>The average (mean) number of cycles of contraction and subsequent relaxation of the heart, usually expressed as beats per minute, obtained from a set of measurements of the heart rate. (NCI)</def-definition>
Mean Heart Rate
Activity
Reuse
Reuse
owl:Class
C79891
To use again.
Reuse
Action
Reuse
Meta-Analysis
C17886
<def-source>CDISC</def-source><def-definition>The formal evaluation of the quantitative evidence from two or more trials bearing on the same question. NOTE: This most commonly involves the statistical combination of summary statistics from the various trials, but the term is sometimes also used to refer to the combination of the raw data. [from ICH E9 Glossary]</def-definition>
Research Activity
owl:Class
meta-analysis
C0920317
Meta-Analysis
CDISC
A set of statistical procedures designed to accumulate experimental and correlational results across independent studies that address a related set of research questions.
Meta-Analysis
Meta-Analysis
Clinical Data Interchange Standards Consortium Glossary Terminology
Statistical Technique
Clinical Data Interchange Standards Consortium Terminology
Individual Case Safety Report Terminology
owl:Class
Hospitalization
Hospitalization
C25179
The condition of being treated as a patient in a hospital.
Health Care Activity
Adverse Event Outcome ICSR Terminology
FDA
Hospitalization
Healthcare Activity
C0019993
Hospitalization
CL364723
owl:Class
Statistical Technique
Multiple Comparison Adjustment
Multiple Comparison Adjustment
Multiple Comparison Adjustment
A procedure used for correction of p-value due to multiple testing.
Quantitative Concept
Multiple Comparison Adjustment
C61601
SHBG
Protein or Enzyme Type Measurement
The determination of the amount of sex hormone binding protein present in a sample.
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Code
Laboratory Procedure
Endocrine Test
CDISC SDTM Laboratory Test Terminology by Name
C0202218
Clinical Data Interchange Standards Consortium Terminology
Sex Hormone Binding Globulin
Sex Hormone Binding Protein Measurement
owl:Class
Sex Hormone Binding Protein Measurement
Sex Hormone Binding Protein Measurement
Sex Hormone Binding Protein Measurement
CDISC
<def-source>CDISC</def-source><def-definition>A measurement of the sex hormone binding (globulin) protein in a biological specimen.</def-definition>
CDISC SDTM Terminology
C74745
Sex Hormone Binding Protein
epidural block
Regional Anesthesia Procedure
An anesthetic procedure that involves administering pharmaceutical agents into the epidural space of the spinal canal. Frequently administered agents include local anesthetics and analgesics.
<def-source>NCI-GLOSS</def-source><def-definition>An injection of an anesthetic drug into the space between the wall of the spinal canal and the covering of the spinal cord.</def-definition>
Newborn Screening
owl:Class
Therapeutic or Preventive Procedure
Epidural Block
C15642
Epidural Block
Epidural Block
C0002913
Epidural Block
Antibody-Directed Enzyme Prodrug Therapy
Antibody-Directed Enzyme Prodrug Therapy
ADEPT
C16022
Antibody-Directed Enzyme Prodrug Therapy
CL004769
owl:Class
Therapeutic or Preventive Procedure
Antibody-Directed Enzyme Prodrug Therapy
A systemic therapy which ensures that a specific prodrug is not converted into the active moiety anywhere but at the sites where the enzyme-linked, tumor-specific antibodies have localized.
Biological Immunotherapy
Diagnostic Procedure
High Resolution Computed Tomography
High Resolution Computed Tomography
owl:Class
High Resolution Computed Tomography
Defined as thin section (1-2 mm collimation) CT optimized by using a high-spatial-frequency (bone) algorithm. (from Radiol Clin North Am 1991;29:1043-9)
High Resolution Computed Tomography
C20644
CL097194
Computed Tomography
C15830
Palliative Care, Other Than Pain and Hospice
owl:Class
CL000671
Supportive care that is not hospice or pain relief
Palliative Care, Other Than Pain and Hospice
Health Care Activity
Palliative Therapy
Palliative Care, Other Than Pain and Hospice
Palliative Care, Other Than Pain and Hospice
C53325
Confidence Limit
owl:Class
Either of the two numbers that specify the endpoints of a confidence interval.
Confidence Limit
Dispersion
Confidence Limit
Quantitative Concept
Confidence Limit
C0237530
Confidence Limits
C18001
C0442015
Digital X-Ray
Digital X-Ray
Digital X-Ray
Diagnostic Procedure
owl:Class
Digital X-Ray
Acquisition or display of radiographic images using digital techniques; includes digital video fluoroscopy, scan-projection radiography (SPR), digital subtraction and angiography (DSA), digital intravenous angiography (DIVA), and computed tomography. (CRC Dictionary and Handbook of Nuclear Medicine and Clinical Imaging, 1990)
Imaging Technique
Radical Retropubic Prostatectomy
Radical Retropubic Prostatectomy
Retropubic Prostatectomy
CL355428
Radical Retropubic Prostatectomy
Radical Retropubic Prostatectomy
Therapeutic or Preventive Procedure
owl:Class
C51884
Radical Prostatectomy
C15836
The Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial, or PLCO Trial, is a large-scale study to determine if certain tests will reduce the number of deaths from these cancers. Sponsored by the National Cancer Institute (NCI), the study will involve 148,000 men and women ages 55 through 74 at medical facilities in 9 geographic areas across the United States. (Cancer Facts Screening: Questions and Answers About the PLCO Cancer Screening Trial)
Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
CL000727
Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PLCO
Cancer Research
Research Activity
owl:Class
Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
Blood Cell Count Ratio Measurement
CL371508
C67208
Blood Cell Count Ratio Measurement
Blood Cell Count
Laboratory Procedure
The determination of the ratio of one blood cell component lto another in a blood sample. The measurement may be expressed as either a ratio or a percentage.
Blood Cell Count Ratio Measurement
owl:Class
Blood Cell Count Ratio Measurement
C71313
Health Care Activity
Screening Questionnaire Administration
Questionnaire Administration
Screening Questionnaire Administration
Screening Questionnaire Administration
CL376105
owl:Class
Disease Screening
Screening Questionnaire Administration
Lipoprotein a Measurement
C82022
owl:Class
The determination of the amount of lipoprotein a present in a sample.
Lipoprotein a Measurement
Lipoprotein a Measurement
Lipoprotein a Measurement
Protein or Enzyme Type Measurement
owl:Class
PR-
Progesterone Receptor Negative
Progesterone Receptor Negative
Progesterone Receptor Negative
Clinical Attribute
negative progesterone receptor
<def-source>NCI-GLOSS</def-source><def-definition>Breast cancer cells that do not have a protein (receptor molecule) to which progesterone will attach. Breast cancer cells that are PR- do not need the hormone progesterone to grow and usually do not respond to hormonal therapy.</def-definition>
Progesterone Receptor Negative
progesterone receptor negative
C15497
Progesterone Receptor Status
CL054783
C0162801
Molecular Analysis
Sequence Analysis
C17565
owl:Class
Sequence Analysis
Sequence Analysis
Laboratory Procedure
The determination of the sequence of component residues in a macromolecule, e.g. amino acids in a protein or nucleotide bases in DNA/RNA or the computational analysis performed to determine the similarities between nonidentical proteins or molecules of DNA or RNA.
Sequence Analysis
C0522536
C51673
Allografting
Grafting or transplanting cells, tissues, or organs between genetically non-identical individuals.
owl:Class
Allografting
Allografting
Surgical Procedure by Method
Therapeutic or Preventive Procedure
Allografting
Her2/Neu Status
owl:Class
C16152
The presence or absence of Her2/Neu on a tissue sample.
Her2/Neu Value
Clinical Attribute
CL014336
Her2/Neu Status
Her2/Neu Status
Her2/Neu Status
Clinical Trial Eligibility Criteria
Neoadjuvant
<def-source>NCI-GLOSS</def-source><def-definition>Treatment given before the primary treatment. Examples of neoadjuvant therapy include chemotherapy, radiation therapy, and hormone therapy.</def-definition>
owl:Class
C0600558
Neoadjuvant Therapy
Neoadjuvant Therapy
induction therapy
Preoperative Therapy
Therapeutic Procedure
Therapeutic or Preventive Procedure
neoadjuvant therapy
Neoadjuvant Therapy
C15665
Induction Therapy
Neoadjuvant Therapy
<def-source>NCI-GLOSS</def-source><def-definition>Treatment designed to be used as a first step toward shrinking the cancer and in evaluating response to drugs and other agents. Induction therapy is followed by additional therapy to eliminate whatever cancer remains.</def-definition>
Crystal Growth Measurement
CDISC SEND Terminology
CDISC
owl:Class
CDISC SDTM Terminology
Amorphous Crystal Measurement
CYAMORPH
Amorphous Crystals
CDISC SDTM Laboratory Test Terminology by Code
Laboratory Procedure
Amorphous Crystal Measurement
Amorphous Crystal Measurement
C74665
Clinical Data Interchange Standards Consortium Terminology
Amorphous Crystal Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the amorphous (Note: phosphate or urate, depending on pH) crystals present in a biological specimen.</def-definition>
The determination of the amount of amorphous crystals present in a sample.
CL384363
CDISC SDTM Laboratory Test Terminology by Name
Edit
Edit
Activity
C70595
owl:Class
Instruction Imperative
Edit
CL375796
The act of preparing by correcting, revising, or adapting.
Edit
Clinical Study by Phase
C54721
Phase 0 Trial
owl:Class
Phase 0 Trial
Research Activity
Phase 0
Phase 0 Trial
CL360700
Pre-Clinical Trial
A clinical trial that uses an investigational agent that is available only in very limited quantities and which has never previously given to humans or for which there is extremely limited human experience. Phase 0 clinical trials are intended to enable researchers to understand the path of the drug in the body and its efficacy. Adverse event reporting in Phase 0 trials is expedited.
Phase 0 Trial
<def-source>MSH2001</def-source><def-definition>The attitude that grants freedom of expression and activity to another individual, but not necessarily with sanction or approval.</def-definition>
Permissiveness, Behavior
Permissiveness, Behavior
C0031166
Permissiveness, Behavior
Personal Behavior
owl:Class
Individual Behavior
Permissiveness, Behavior
C16971
Administrative Activity
C49235
Administrative Activity
Activity
owl:Class
Activities involved in the performance of executive, supervisory, or managerial duties.
CL354881
Activity
Administrative Activity
Administrative Activity
Fundamental research designed to obtain or increase general knowledge about cancer, performed without the goal of solving or addressing a specific cancer-related issue or condition.
C16085
Research Activity
Basic Cancer Research
Basic Cancer Research
owl:Class
Basic Science Research
Basic Cancer Research
Basic Cancer Research
CL008571
Laboratory Procedure
CDISC SEND Terminology
Reticulocyte Count
CL356014
CDISC SDTM Laboratory Test Terminology by Code
RETI
Reticulocyte Count
Clinical Data Interchange Standards Consortium Terminology
CDISC
Reticulocytes
Reticulocyte Count
<def-definition>A measurement of the reticulocytes per unit of a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Terminology
Reticulocyte Count
Erythrocyte Count
owl:Class
The determination of the number of reticulocytes in a blood sample.
C51947
CDISC SDTM Laboratory Test Terminology by Name
owl:Class
CL375837
Therapeutic or Preventive Procedure
Myringotomy with Ear Tube Placement
Myringotomy
Myringotomy with Ear Tube Placement
C70906
Myringotomy with Ear Tube Placement
Myringotomy with Ear Tube Placement
A surgical procedure where an incision is made through the eardrum, and a plastic or metal tube is inserted.
Booster
booster
CL042544
Vaccine Therapy
Therapeutic or Preventive Procedure
Booster
A second or later vaccine dose, separated from the first by time, to increase, extend, or maintain the immune response of the previous vaccination.
<def-source>NCI-GLOSS</def-source><def-definition>In medicine, refers to a vaccination given after a previous vaccination. A booster helps maintain or increase a protective immune response.</def-definition>
owl:Class
Booster
C28320
Booster
Right Hemihepatectomy
Right Hemihepatectomy
owl:Class
Surgical removal of the right hemisphere of the liver.
Therapeutic or Preventive Procedure
Right Hemihepatectomy
Partial Hepatectomy
C51569
Right Hemihepatectomy
Procedure_Has_Completely_Excised_Anatomy only 'Right Lobe of the Liver'
CL356022
Professional or Occupational Group
Action
C67226
Software Development
Computer Software Development
owl:Class
Software Development
Software Development
The design and writing of computer programs. Software development includes the design of the user interface and the program architecture as well as programming the source code. A somewhat broader scope of computer programming or a specialty of project managing.
Software Development
C0872272
in vitro-treated PBPC transplantation
in vitro-Treated Peripheral Blood Stem Cell Transplantation
in vitro-Treated Peripheral Blood Stem Cell Transplantation
CL034166
in vitro-treated peripheral blood progenitor cell transplantation
C15532
in vitro-Treated Peripheral Blood Stem Cell Transplantation
Peripheral Blood Stem Cell Transplantation
owl:Class
Therapeutic or Preventive Procedure
in vitro-Treated Peripheral Blood Stem Cell Transplantation
Molecular Biology Research Technique
Laboratory Procedure
Dideoxy Chain Termination DNA Sequencing
Dideoxy Chain Termination DNA Sequencing
owl:Class
Nucleic Acid Sequencing
DNA sequencing in which chain termination is caused by incorporation of a dideoxynucleotide into a growing DNA strand.
Dideoxy Chain Termination DNA Sequencing
C19641
Dideoxy Chain Termination DNA Sequencing
CL008142
Sanger Sequencing
owl:Class
Vital Signs Test
Newborn Screening
Observation
Vital Signs
C49672
Vital Signs
Vital Signs
The name given to the test that analyzes a particular set of vital signs including temperature, respiratory rate, heart beat (pulse), and blood pressure.
VS
Vital Signs
Quantitative Concept
CL356147
Drug Modulation Therapy
Therapeutic or Preventive Procedure
CL366196
C63492
Drug Modulation Therapy
Drug Modulation Therapy
Drug Modulation Therapy
owl:Class
Therapeutic Procedure
Replacement Therapy
C15471
Administration of a body substance to compensate for the loss, as from disease or surgery, of a gland or tissue that would normally produce the substance.
Therapeutic or Preventive Procedure
Biological Therapy
Replacement Therapy
owl:Class
Replacement Therapy
C0279033
Replacement Therapy
Regional Chemotherapy
Therapeutic or Preventive Procedure
CL002741
owl:Class
Topical Chemotherapy
Topical Chemotherapy
topical chemotherapy
Topical Chemotherapy
Topical Chemotherapy
C15914
<def-source>NCI-GLOSS</def-source><def-definition>(kee-mo-THER-a-pee) Treatment with anticancer drugs in a lotion or cream applied to the skin.</def-definition>
Urate Measurement
Urate Measurement
owl:Class
C64814
CL385676
CDISC SDTM Laboratory Test Terminology by Name
Urate
Urate Measurement
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Terminology
Urate Measurement
Clinical Data Interchange Standards Consortium Terminology
A quantitative measurement of the amount of urate present in a sample.
<def-source>CDISC</def-source><def-definition>A measurement of the urate in a biological specimen.</def-definition>
URATE
CDISC
CDISC SEND Terminology
Uric Acid
Chemistry Test
Laboratory Procedure
Anisocyte Measurement
Anisocyte Measurement
Anisocyte Measurement
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Laboratory Test Terminology by Code
Anisocyte Measurement
Clinical Data Interchange Standards Consortium Terminology
The determination of the number of anisocytes present in a sample.
C74797
Laboratory Procedure
Anisocytes
ANISO
Erythrocyte Count
owl:Class
CDISC SDTM Terminology
CDISC
<def-definition>A measurement of the inequality in the size of the red blood cells in a whole blood specimen.</def-definition><def-source>CDISC</def-source>
CL384368
CDISC SEND Terminology
stereotaxis
CL094812
<def-source>NCI-GLOSS</def-source><def-definition>(stair-ee-o-TAK-sis) Use of a computer and scanning devices to create three-dimensional pictures. This method can be used to direct a biopsy, external radiation, or the insertion of radiation implants.</def-definition>
Diagnostic Procedure
Stereotaxis
owl:Class
C20642
Stereotaxis
A minimally-invasive form of surgical intervention which makes use of a three-dimensional frame of reference usually based on the Cartesian coordinate system, to locate small targets inside the body and to perform on them some action such as ablation (removal), biopsy, lesion, injection, stimulation, implantation, etc.
Stereotaxis
Three Dimensional Imaging
Stereotaxis
owl:Class
Tooth Extraction
C51770
Extraction of Tooth
Extraction of Tooth
Extraction of Tooth
C0040440
Extraction of Tooth
Therapeutic or Preventive Procedure
Dental Procedure
Family-Wise Error Rate
C64215
owl:Class
Quantitative Concept
FWER
Multiple Comparison Adjustment
CL369086
Family-Wise Error Rate
Family-Wise Error Rate
Family-Wise Error Rate
A statistical method used for multiple testing corrections to control the expected proportion of false positives (Type I eror) among rejected tests or hypotheses. It is more stringent than other mutiple testing corrections and thereby, will allow very few false positives.
Glucagon-like Peptide-1 Measurement
owl:Class
Glucagon-like Peptide-1 Measurement
Glucagon-like Peptide-1 Measurement
Glucagon-like Peptide-1 Measurement
The determination of the amount of glucagon-like peptide-1 present in a sample.
C80183
Laboratory Procedure
Protein or Enzyme Type Measurement
C15369
Therapeutic or Preventive Procedure
Bone Marrow Transplantation
Allogeneic Bone Marrow Transplantation
Allo BMT
Allogeneic Bone Marrow Transplantation
Allogeneic BMT
owl:Class
A clinical treatment in which a patient receives bone marrow from a compatible, but not genetically identical, donor.
allogeneic bone marrow transplantation
Allogeneic Bone Marrow Transplantation
<def-source>NCI-GLOSS</def-source><def-definition>(AL-o-jen-AY-ik) A procedure in which a person receives stem cells, the cells from which all blood cells develop, from a compatible, though not genetically identical, donor.</def-definition>
C0149615
Allogeneic Bone Marrow Transplantation
Complete removal of the fallopian tube(s).
Complete Salpingectomy
CL353272
Therapeutic or Preventive Procedure
Complete Salpingectomy
Complete Salpingectomy
Salpingectomy
owl:Class
Complete Salpingectomy
Procedure_Has_Completely_Excised_Anatomy only 'Fallopian Tube'
C51941
Aging and Nutrition
owl:Class
Occupation or Discipline
Aging and Nutrition
C15659
C0597119
Aging and Nutrition
Nutritional Study
Aging and Nutrition
Functional Concept
The study of how nutritional needs change with aging.
Detection and measurement of the resonant spectra of molecular species in a tissue or sample.
<def-source>MSH2001</def-source><def-definition>Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).</def-definition>
Magnetic Resonance Spectroscopy
C16810
Magnetic Resonance Spectroscopy
C0024487
<def-source>NCI-GLOSS</def-source><def-definition>Magnetic resonance spectroscopic imaging. A noninvasive imaging method that provides information about cellular activity (metabolic information). It is used along with magnetic resonance imaging (MRI) which provides information about the shape and size of the tumor (spatial information).</def-definition>
Spectroscopy, NMR
Diagnostic Procedure
Spectroscopy, Nuclear Magnetic Resonance
Magnetic Resonance Spectroscopy
Magnetic Resonance Spectroscopy
Spectroscopy, MR
MRSI
Spectroscopy
owl:Class
<def-source>CDISC</def-source><def-definition>A measurement of the hepatitis A viral load in a biological specimen using polymerase chain reaction.</def-definition>
The determination of the hepatitis A viral load present in a sample using polymerase chain reaction.
CDISC SDTM Terminology
Hepatitis A Viral Load PCR Measurement
CDISC
C74724
CL384397
owl:Class
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Name
HAVPCR
Polymerase Chain Reaction
Hepatitis A Viral Load PCR Measurement
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Code
Hepatitis A Viral Load PCR Measurement
Hepatitis A Viral Load PCR Measurement
Laboratory Procedure
HAV PCR Viral Load
Therapeutic or Preventive Procedure
Videothoracoscopy
Videothoracoscopy
C18306
Thoracoscopy
Videothoracoscopy
Videothoracoscopy
CL032128
Diagnostic Procedure
owl:Class
Endoscopic examination of the thoracic cavity, with a camera or similar device attached to an endoscope for viewing or recording the images generated during the procedure.
Aspiration
Aspiration
Procedure using suction, usually with a thin needle and syringe, to removal bodily fluid or tissue.
<def-source>NCI-GLOSS</def-source><def-definition>(as-per-AY-shun) Removal of fluid from a lump, often a cyst, with a needle and a syringe.</def-definition>
Therapeutic or Preventive Procedure
Aspiration
Diagnostic Procedure
C0349707
owl:Class
Aspiration
aspiration
Surgical Procedure by Method
C15631
Age-adjusted PSA
Age-adjusted PSA
C20120
Prostate Specific Antigen Measurement
Age-adjusted PSA
Age-adjusted PSA
Classification
owl:Class
CL017744
Prostate-specific antigen (PSA) level defined according to specific age groups or ranges, which takes into account the natural increase of PSA levels with increased age.
tomography
<def-source>NCI-GLOSS</def-source><def-definition>A series of detailed pictures of areas inside the body; the pictures are created by a computer linked to an x-ray machine.</def-definition>
computed tomography
CT
Computerized Tomography
Computed Tomography
Diagnostic Procedure
Computerized Axial Tomography
Computed Tomography
owl:Class
Computed Tomography
computerized axial tomography
C17204
C0040405
CAT
A method of examining body organs by scanning them with X rays and using a computer to construct a series of cross-sectional scans along a single axis.
computerized tomography
CAT Scan
Computed Tomography
CAT scan
Diagnostic Imaging
CT scan
Matrix Metalloproteinase 1 Measurement
Protein or Enzyme Type Measurement
Matrix Metalloproteinase 1 Measurement
Matrix Metalloproteinase 1 Measurement
The determination of the amount of matrix metalloproteinase 1 present in a sample.
Matrix Metalloproteinase 1 Measurement
C80192
Laboratory Procedure
owl:Class
Genetic Counseling
owl:Class
Counseling
The process whereby an expert in hereditary disorders provides information about risk and clinical burden of a disorder or disorders to patients or relatives in families with genetic disorders as an aid to making informed and responsible decisions about marriage, children, early diagnosis, and handling disability.
Genetic Counseling
Genetic Counseling
Genetic Counseling
C15240
<def-source>NCI-GLOSS</def-source><def-definition>A communication process between a specially trained health professional and a person concerned about the genetic risk of disease. The person's family and personal medical history may be discussed, and counseling may lead to genetic testing.</def-definition>
genetic counseling
Health Care Activity
C0017382
Biopsy of Pylorus
CL355001
Pyloric Biopsy
C51584
Biopsy of Pylorus
Removal of tissue from the pylorus for microscopic examination, using an endoscope.
Procedure_Has_Partially_Excised_Anatomy only Pylorus
Biopsy of Pylorus
Biopsy of Pylorus
owl:Class
Diagnostic Procedure
Endoscopic Biopsy
Therapeutic or Preventive Procedure
C68770
Preoperative Chemotherapy
Preoperative Chemotherapy
The use of a chemotherapy agent that is administered to a patient prior to the surgical removal of a tumor.
owl:Class
Chemotherapy
Preoperative Chemotherapy
Preoperative Chemotherapy
CL374347
Complement C4 Measurement
C80177
The determination of the amount of complement C4 present in a sample.
Complement C4 Measurement
Complement C4 Measurement
Complement Measurement
Complement C4 Measurement
owl:Class
Laboratory Procedure
CDISC
<def-source>CDISC</def-source><def-definition>The maximum time between successive cycles of contraction and subsequent relaxation of the ventricles, usually expressed as beats per minute, obtained from a set of measurements of the ventricular rate. (NCI)</def-definition>
Maximum Ventricular Heart Rate
VRMAX
The maximum time between successive cycles of contraction and subsequent relaxation of the ventricles, usually expressed as beats per minute, obtained from a set of measurements of the ventricular rate.
Ventricular Heart Rate
CL365063
Maximum Ventricular Heart Rate
Maximum Ventricular Heart Rate
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM ECG Test Terminology by Code
C62154
Quantitative Concept
CDISC SDTM Terminology
Maximum Ventricular Heart Rate
CDISC SDTM ECG Test Name Terminology
Summary (Max) Ventricular Rate
owl:Class
CDISC
Statistical Median
<def-source>CDISC</def-source><def-definition>The middle value in a data set; that is, just as many values are greater than the median and lower than the median value. (With an even number of values, the conventional median is halfway between the two middle values.)</def-definition>
Median
Median
Qualitative Concept
Median
Median
Clinical Data Interchange Standards Consortium Terminology
Measure of Central Tendency
The value which has an equal number of values greater and less than it.
Clinical Data Interchange Standards Consortium Glossary Terminology
C28007
CL034939
median
<def-source>NCI-GLOSS</def-source><def-definition>A statistics term. The middle value in a set of measurements.</def-definition>
owl:Class
Fracture Fixation
Fracture Fixation
Therapeutic or Preventive Procedure
Fracture Fixation
C0016641
Orthopedic Surgical Procedure
Procedure_Has_Target_Anatomy only Bone
owl:Class
C52008
Fracture Fixation
Fatigue Assessment and Management
Fatigue Assessment and Management
CL029634
Health Care Activity
Supportive Care
owl:Class
C15494
Fatigue Assessment and Management
Fatigue Assessment and Management
Mind-Body Intervention Procedure
C0679674
Spiritual Therapy
Spiritual Therapy
Spiritual Therapy
C51972
owl:Class
Spiritual Therapy
Mental Process
CL000912
Site Visit
Visit
owl:Class
Governmental or Regulatory Activity
Occupational Activity
C19032
Site Visit
Site Visit
Site Visit
A visit from an oversite group to a site of a study or research for fact gathering, peer review, or compliance with regulations.
Artificial Kidney Dialysis
Renal Dialysis
C15248
owl:Class
C0019004
Therapeutic or Preventive Procedure
Kidney Dialysis
Hemodialysis
Dialysis
Hemodialysis
Extracorporeal Dialysis
Hemodialysis
Hemodialysis
Health Care Activity
C15870
Vaccine Related Development, Non-Cancer; Non-AIDS
Vaccine Related Development, Non-Cancer; Non-AIDS
CL001072
Vaccine Related Development, Non-Cancer; Non-AIDS
Vaccine Related Development, Non-Cancer; Non-AIDS
Vaccine Development
owl:Class
FDA
Ophthalmologic Surgical Procedure
Vitrectomy
Patient Code (Appendix B)
owl:Class
Vitrectomy
Vitrectomy
Vitrectomy
Therapeutic or Preventive Procedure
Procedure_Has_Excised_Anatomy only 'Vitreous Body'
CL355594
C50837
Patient Problem Codes FDA CDRH
Assessment of individual responses to age appropriate stimuli.
owl:Class
Diagnostic Procedure
Behavioral Assessment
Behavioral Assessment
C81234
Diagnostic Procedure
Newborn Screening
Behavioral Assessment
Behavioral Assessment
CL004426
Nutrition, Caffeine
Nutrition, Caffeine
Nutrition, Caffeine
Nutrition, Caffeine
Role of caffeine in cancer causation or prevention and in general health.
C16014
Nutrition, Dietary Components
Research Activity
owl:Class
Healthcare Activity
Remedial Action
Remedial Action
Remedial Activity
An action taken in order to cure or restore to health.
CL357043
C53605
Remedial Action
Remedial Action
Occupational Activity
<def-source>FDA</def-source><def-definition>Any action, other than routine maintenance or servicing of a device, necessary to prevent recurrence of a reportable event.</def-definition>
owl:Class
Interferon Measurement
The determination of the amount of interferon present in a sample.
C81868
Interferon Measurement
Interferon Measurement
Laboratory Procedure
Interferon Measurement
Cytokine Measurement
owl:Class
Statistical Imputation
C81201
Baseline Observation Carried Forward Imputation Technique
owl:Class
Baseline Observation Carried Forward Imputation Technique
Quantitative Concept
Baseline Observation Carried Forward Imputation Technique
The substitution of a missing data point with the value from the subject's baseline observation that is not missing.
Baseline Observation Carried Forward Imputation Technique
Photodynamic Therapy
C0031740
PDT
Photodynamic Therapy
Photoradiation Therapy
Use of light activated drugs (photosensitizing agents) to kill cancer cells.
Photodynamic Therapy
<def-source>NCI-GLOSS</def-source><def-definition>(foe-toe-dye-NAM-ik) Treatment with drugs that become active when exposed to light. These drugs kill cancer cells.</def-definition>
Chemotherapy
C15300
photodynamic therapy
owl:Class
Photodynamic Therapy
Therapeutic or Preventive Procedure
Echocardiography
A procedure that uses sound waves to measure characteristics of disturbed bood flow, such as direction, velocity and turbulence. This enables the examiner to differentiate between normal and abnormal flow patterns and, in some cases, to quantitate those characteristics that are helpful in determining the severity of abnormal flow states.
Doppler Echocardiography
Doppler Study
Doppler Echocardiography
C0013520
Doppler Echocardiography
C38634
Doppler Echocardiography
Diagnostic Procedure
owl:Class
CDISC
Haptoglobin Protein Measurement
Haptoglobin Protein Measurement
CDISC SDTM Laboratory Test Terminology by Code
<def-source>CDISC</def-source><def-definition>A measurement of the haptoglobin protein in a biological specimen.</def-definition>
Clinical Data Interchange Standards Consortium Terminology
owl:Class
CDISC SDTM Terminology
HAPTOG
The determination of the amount of haptoglobin protein present in a sample.
Haptoglobin Protein Measurement
Haptoglobin
Laboratory Procedure
C74740
Haptoglobin Protein Measurement
CDISC SDTM Laboratory Test Terminology by Name
Protein or Enzyme Type Measurement
C0919773
CDISC SEND Terminology
Glutathione-S-Transferase Measurement
The determination of the amount of glutathione-s-transferase present in a sample.
Glutathione-S-Transferase Measurement
Protein or Enzyme Type Measurement
Laboratory Procedure
C80185
Glutathione-S-Transferase Measurement
Glutathione-S-Transferase Measurement
owl:Class
Breast Conservation Treatment
<def-source>MSH2001</def-source><def-definition>Removal of only enough breast tissue to ensure that the margins of the resected surgical specimen are free of tumor.</def-definition>
Breast Conservation Treatment
Breast conservation treatment is defined as excision of the primary tumor and adjacent breast tissue, followed by radiation therapy. This procedure is also referred to as lumpectomy, segmental mastectomy, or partial mastectomy. (from Consensus Statements: Treatment of Early-stage Breast Cancer, 1990)
Breast-Conserving Surgery
breast-conserving surgery
BCT
C0917927
Breast Conservation Treatment
C15280
Therapeutic or Preventive Procedure
Breast Cancer Therapeutic Procedure
<def-source>NCI-GLOSS</def-source><def-definition>An operation to remove the breast cancer but not the breast itself. Types of breast-conserving surgery include lumpectomy (removal of the lump), quadrantectomy (removal of one quarter of the breast), and segmental mastectomy (removal of the cancer as well as some of the breast tissue around the tumor and the lining over the chest muscles below the tumor).</def-definition>
Breast Conservation Treatment
owl:Class
Revision of Total Knee Arthroplasty
C51567
Therapeutic or Preventive Procedure
Revision of Total Knee Arthroplasty
Orthopedic Surgical Procedure
owl:Class
Revision of Total Knee Arthroplasty
CL355466
Procedure_Has_Target_Anatomy only 'Knee Joint'
Revision of Total Knee Arthroplasty
Pancreatic Elastase Measurement
Pancreatic Elastase Measurement
Pancreatic Elastase Measurement
owl:Class
C82028
Protein or Enzyme Type Measurement
Pancreatic Elastase Measurement
The determination of the amount of pancreatic elastase present in a sample.
C53227
owl:Class
Beta Distribution
Continuous Distribution
Beta Distribution
CL355693
A unimodal distribution with confined lower and upper bounds.
Quantitative Concept
Beta Distribution
Beta Distribution
CDISC SDTM Laboratory Test Terminology by Code
Spermatozoa Cell Count
Spermatozoa Cell Count
The determination of the number of spermatozoa cells present in a sample.
CDISC
CDISC SDTM Terminology
Spermatozoa Cell Count
Spermatozoa Cell Count
CDISC SEND Terminology
owl:Class
<def-source>CDISC</def-source><def-definition>A measurement of the spermatozoa cells present in a biological specimen.</def-definition>
SPERM
C74663
CL384704
Cell Count
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
Spermatozoa
Clinical Data Interchange Standards Consortium Terminology
Tumor Necrosis Factor Assay
C0201595
owl:Class
Tumor Necrosis Factor Assay
An immunoassay to detect Tumor Necrosis Factor (TNF), which is a potent lymphoid factor, and exerts cytotoxic effects on a wide range of tumor cells and other target cells. Utilizes monoclonal antibody to TNF immobilized on microtitre plate.
C17635
Tumor Necrosis Factor Assay
Bioassay, in vitro
TNF Assay
Tumor Necrosis Factor Assay
Laboratory Procedure
C0700287
C25651
Action
Reporting
The act of providing a short account.
owl:Class
Reporting
Reporting
Reporting
Activity
owl:Class
Biostatistical Methods
Biostatistical Methods
Statistical Technique
C19680
Techniques used to statistically analyze biological data.
Biostatistical Methods
Biostatistical Methods
CL008497
Research Activity
Transmission Electron Microscopy
C78874
A transmission electron microscopy-based imaging technique in which the transmitted and diffracted beams are allowed to interfere, creating phase contrast that allows atomic columns to be documented.
owl:Class
Electron Phase Contrast Imaging
HRTEM
High Resolution Transmission Electron Microscopy
CL387718
Laboratory Procedure
High Resolution Transmission Electron Microscopy
High Resolution Transmission Electron Microscopy
Research Activity
High Resolution Transmission Electron Microscopy
Gas Sorption
owl:Class
A technique where a sample is heated and degassed to remove contaminants, followed by exposure to doses of an inert gas. The adsorption of the gas is measured and, subsequently, the gas is withdrawn while the desorption is measured. The profile of adsorption and desorption of the gas at various vacuum pressures can be used to determine the surface area of the sample.
Gas Sorption
Gas Sorption
C78875
CL387713
Gas Sorption
Physical Chemical Technique
Laboratory Procedure
Research Activity
Provided
Provide
Supplied
owl:Class
Supply what is desired or needed.
Activity
Supply
C80514
Provide
Provide
Provide
Action
The method referring to the delivery of a fetus through the vaginal canal with assistance of obstetrical forceps.
Forceps Delivery
Birth Method of Delivery
owl:Class
C81248
Forceps Delivery
Newborn Screening
Therapeutic or Preventive Procedure
Forceps Delivery
Forceps Delivery
Laboratory Procedure
The process of experimentally manipulating the immune response in order to redirect its specificity and intensity by developing novel molecular, chemical, and cellular procedures to alter the outcome of immune reactions.
Immunology Test
Immune Targeting
Immune Targeting
CL007309
C19631
owl:Class
Immune Targeting
Immune Targeting
CDISC SEND Terminology
C74647
Laboratory Procedure
The determination of the ratio of nucleated red blood cells compared to erythrocytes present in a sample. The measurement may be expressed as a ratio or percentage.
<def-source>CDISC</def-source><def-definition>A relative measurement (ratio or percentage) of the nucleated erythrocytes (large, immature nucleated erythrocytes) to all erythrocytes in a biological specimen.</def-definition>
Nucleated Erythrocytes/Erythrocytes
CDISC SDTM Laboratory Test Terminology by Code
Nucleated Red Blood Cell to Erythrocyte Ratio Measurement
RBCNURBC
CDISC SDTM Terminology
Nucleated Red Blood Cell to Erythrocyte Ratio Measurement
CDISC SDTM Laboratory Test Terminology by Name
Nucleated Red Blood Cell to Erythrocyte Ratio Measurement
Nucleated Red Blood Cell to Erythrocyte Ratio Measurement
CDISC
Clinical Data Interchange Standards Consortium Terminology
Blood Cell Count Ratio Measurement
Nucleated Red Blood Cells/Erythrocytes
CL384333
owl:Class
Surgical Procedures
Surgical
Surgery
Operation
Surgically
Intervention or Procedure
Surgical Procedure
C15329
owl:Class
Therapeutic or Preventive Procedure
Surgical Procedure
C0543467
Surgical Interventions
A diagnostic or treatment procedure performed by manual and/or instrumental means, often involving an incision and the removal or replacement of a diseased organ or tissue; of or relating to or involving or used in surgery or requiring or amenable to treatment by surgery.
<def-source>NCI-GLOSS</def-source><def-definition>(SERJ-uh-ree) A procedure to remove or repair a part of the body or to find out whether disease is present. An operation.</def-definition>
Surgical Procedure
Surgical Procedure
surgery
Diagnostic Procedure
Cutaneous Oximetry
Cutaneous Oximetry
Cutaneous Oximetry
Diagnostic Procedure
owl:Class
C41375
C0040656
Cutaneous Oximetry
Noninvasive measurement or determination of the partial pressure of oxygen and carbon dioxide locally in the capillaries of a tissue by the application to the skin of a special set of electrodes. These electrodes contain photoelectric sensors capable to detect the specific wavelengths of radiation emitted by oxygenated versus reduced hemoglobin. Tissue oxygenation measurement is a useful tool for appropriate patient selection for HBO therapy and for choosing strategies for management of peripheral vascular diseases, chronic nonhealing wounds and other conditions.
Diagnostic Procedure
Activity
Use of robots and other automated techniques to screen large numbers of samples.
High Throughput Assay
C18472
owl:Class
Disease Screening
High Throughput Screening
C0872187
High Throughput Screening
High Throughput Screening
High Throughput Screening
Kidney Transplantation
kidney grafting
Procedure_Has_Target_Anatomy only Kidney
Urologic Surgical Procedure
Organ Transplantation
Kidney Transplantation
<def-source>MSH2001</def-source><def-definition>The transference of a kidney from one human or animal to another.</def-definition>
Kidney Transplantation
renal transplantation
C0022671
Therapeutic or Preventive Procedure
Kidney Transplantation
owl:Class
C15265
Excision of Bile Duct
Excision of Bile Duct
Excision of Bile Duct
owl:Class
Procedure_Has_Excised_Anatomy only 'Bile Duct'
CL353902
Surgical removal of part or all of the bile duct.
Biliary Tract Surgery
Excision
C51577
Excision of Bile Duct
Therapeutic or Preventive Procedure
Occupational Activity
Repair
C0374711
FDA
Repair
C53611
Type Of Remedial Action ICSR Terminology
Repair
Repair
Individual Case Safety Report Terminology
Remedial Action
owl:Class
Apoptosis Induction Therapy
Therapeutic or Preventive Procedure
Apoptosis Induction Therapy
owl:Class
C69413
Apoptosis Induction Therapy
CL375548
Apoptosis Induction Therapy
Cancer Therapeutic Procedure
Kruskal-Wallis Test
Kruskal-Wallis Test
C53248
Kruskal-Wallis Test
owl:Class
Non-Parametric Test
Kruskal-Wallis Test
CL356477
Quantitative Concept
A nonparametric test for finding if three or more independent samples come from populations having the same distribution. It is a nonparametric version of ANOVA.
CL384433
CYAMMBIU
CDISC SDTM Laboratory Test Terminology by Code
CDISC
The determination of the amount of ammonium biurate crystals present in a urine sample.
CDISC SDTM Terminology
Ammonium Biurate Crystals
owl:Class
Urine Ammonium Biurate Crystal Measurement
Crystal Growth Measurement
C74758
Urine Ammonium Biurate Crystal Measurement
Urine Chemistry Measurement
Laboratory Procedure
<def-source>CDISC</def-source><def-definition>A measurement of the ammonium biurate crystals present in a biological specimen.</def-definition>
Urine Ammonium Biurate Crystal Measurement
CDISC SDTM Laboratory Test Terminology by Name
Urine Ammonium Biurate Crystal Measurement
Clinical Data Interchange Standards Consortium Terminology
CDISC SEND Terminology
Mutagenesis where the mutation is caused by the loss of DNA sequences within a gene. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro.
Laboratory Procedure
owl:Class
Deletion Mutagenesis
CL003194
Deletion Mutagenesis
Mutagenesis
Deletion Mutagenesis
Deletion Mutagenesis
C19240
Hepatitis C Viral Load PCR Measurement
CDISC SDTM Terminology
The determination of the hepatitis C viral load in a sample using polymerase chain reaction.
HCV PCR Viral Load
Hepatitis C Viral Load PCR Measurement
Hepatitis C Viral Load PCR Measurement
Clinical Data Interchange Standards Consortium Terminology
C74726
HCVPCR
CDISC SDTM Laboratory Test Terminology by Code
Hepatitis C Viral Load PCR Measurement
CDISC SEND Terminology
<def-source>CDISC</def-source><def-definition>A measurement of the hepatitis C viral load in a sample using polymerase chain reaction.</def-definition>
owl:Class
CDISC
Laboratory Procedure
Polymerase Chain Reaction
CL384400
CDISC SDTM Laboratory Test Terminology by Name
owl:Class
C15790
Cancer Prevention Trial
Clinical Trials, Prevention
Prevention Study
Cancer Prevention Trial
CL000232
Clinical trials that study ways of reducing the risk of getting cancer.
Clinical Study by Targeted Disease or Condition
Research Activity
Cancer Prevention Trial
Cancer Prevention Trial
There are two types of prevention clinical trials: 1) Action studies (doing something) and 2) Agent studies (taking something) to prevent cancer.
owl:Class
Conditions Affecting Unborn Children
CL053945
Child Health Study
Conditions Affecting Unborn Children
Research Activity
Conditions Affecting Unborn Children
Conditions Affecting Unborn Children
C26038
FDA
Patient Monitoring
Remedial Action
Individual Case Safety Report Terminology
C53607
Type Of Remedial Action ICSR Terminology
Health Care Activity
Patient Monitoring
owl:Class
C0030695
Patient Monitoring
Patient Monitoring
Meditation Therapy
C51975
Meditation Therapy
Meditation Therapy
Meditation
owl:Class
Mental Process
C0814263
Mind-Body Intervention Procedure
Meditation Therapy
Continuous and profound contemplation or musing on a subject or series of subjects of a deep or abstruse nature; contemplation of spiritual matters
Nucleated Red Blood Cell Count
CDISC
Nucleated Red Blood Cell Count
Laboratory Procedure
CDISC SEND Terminology
Nucleated Red Blood Cells
C74705
Erythrocyte Count
Clinical Data Interchange Standards Consortium Terminology
C0455282
CDISC SDTM Terminology
owl:Class
Nucleated Erythrocytes
The determination of the number of nucleated red blood cells present in a sample.
CDISC SDTM Laboratory Test Terminology by Code
Nucleated Red Blood Cell Count
Nucleated Red Blood Cell Count
<def-source>CDISC</def-source><def-definition>A measurement of the nucleated erythrocytes (large, immature nucleated erythrocytes) in a biological specimen.</def-definition>
RBCNUC
CDISC SDTM Laboratory Test Terminology by Name
Action
Processing Technique
Processing
The act of preparing or putting through a prescribed procedure.
Processing
Processing
Research Activity
owl:Class
CL343292
Processing
C48177
Research Technique
owl:Class
Cellular Compartment Analysis
Cellular Compartment Analysis
Cell Compartment Analysis
Cell partitioning techniques used to determine the subcellular distribution of molecules of interest.
C20062
CL015630
Cellular Compartment Analysis
Laboratory Procedure
Cellular Compartment Analysis
owl:Class
Hypnotherapy
Mind-Body Intervention Procedure
C0020587
Hypnotherapy
<def-source>NCI-GLOSS</def-source><def-definition>A trance-like state in which a person becomes more aware and focused and is more open to suggestion.</def-definition>
Mental Process
Hypnotherapy
Hypnosis
hypnosis
C15420
Hypnotherapy
Therapeutic use of hypnotism. It has been used to treat phobias and anxiety, to manage pain, and to extinguish habits and addictions. (Taber's)
CL354497
Distal Pancreatectomy
C51647
Partial Pancreatectomy
Therapeutic or Preventive Procedure
Distal Pancreatectomy
Distal Pancreatectomy
Distal Pancreatectomy
owl:Class
Surgical removal of the distal part of the pancreas.
Biopsy of Mouth
owl:Class
C51650
Diagnostic Procedure
Biopsy of Mouth
CL354442
Biopsy
Biopsy of Mouth
Biopsy of Mouth
Procedure_Has_Partially_Excised_Anatomy only 'Oral Cavity'
Removal of tissue from the oral cavity for microscopic examination.
CL000748
C15839
Prevention and Treatment Evaluation
Research Activity
Prevention and Treatment Evaluation
Therapy Evaluation
Prevention and Treatment Evaluation
owl:Class
Prevention and Treatment Evaluation
Research Activity
owl:Class
Intervention Community Trial
CL323534
Intervention Community Trial
Intervention Community Trial
The Intervention Community Trial is a controlled study that involves modification of causal or conjectural causal factors in a population to test a cause-effect relationship.
Community Trial
Intervention Community Trial
C39435
Vertebroplasty
A nonsurgical method for the repair of vertebral fractures and compression due to osteoporosis in which a glue-like material is inserted into the center of the collapsed spinal vertebra in order to stabilize and strengthen the crushed bone.
owl:Class
Orthopedic Surgical Procedure
Procedure_Has_Target_Anatomy only 'Vertebral Column'
Vertebroplasty
C62752
C1303192
Therapeutic or Preventive Procedure
Vertebroplasty
Vertebroplasty
CDISC SEND Terminology
Clinical Data Interchange Standards Consortium Terminology
Protein or Enzyme Type Measurement
Triacylglycerol Lipase Measurement
Triacylglycerol Lipase Measurement
C64807
CDISC SDTM Laboratory Test Terminology by Code
A quantitative measurement of the amount of triacylglycerol lipase present in a sample.
CDISC SDTM Laboratory Test Terminology by Name
Triacylglycerol Lipase
CDISC
Triacylglycerol Lipase Measurement
Laboratory Procedure
<def-source>CDISC</def-source><def-definition>A measurement of the pancreatic lipase in a biological specimen.</def-definition>
CL385185
owl:Class
Triacylglycerol Lipase Measurement
LIPASE
CDISC SDTM Terminology
Clamping Activity
Clamping
C63659
Clamping
CL366462
Clamping
owl:Class
Clamping
Action
To fasten, grip, or support with or as if with a clamp.
Activity
Fractionation, Centrifugation, Equilibrium
Equilibrium Centrifugation
Equilibrium Centrifugation
owl:Class
Laboratory Procedure
Centrifuge through a gradient until a substance reaches equilibrium
Centrifugation
CL004095
Equilibrium Centrifugation
C19396
Equilibrium Centrifugation
Diagnostic Procedure
C43545
Bioelectric Impedance Test
owl:Class
Bioelectric Impedance Analysis
Bioelectric Impedance
Bioimpedance Analysis
A method to assess body composition, i.e., the relative percentages of body weight comprised of fat tissue and lean body mass. It is based on the principle that the resistance to an applied electric current is inversely related to the amount of lean body mass within the body. Impedance is greatest in fat tissue, which contains only 10-20% water, while lean body mass, which contains 70-75% water, allows the signal to pass much more easily.
Bioelectric Impedance Analysis
Bioelectric Impedance Analysis
Bioelectric Impedance Analysis
BIA
Diagnostic Procedure
Bioelectrical Impedance Analysis
CL333610
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Terminology
Bile Acids
<def-definition>A measurement of the total bile acids in a biological specimen</def-definition><def-source>CDISC</def-source>
Bile Acid Measurement
Bile Salt
Chemistry Test
owl:Class
Bile Acid
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Laboratory Test Terminology by Code
Bile Acid Measurement
The determination of the amount of bile acids present in a sample.
BILEAC
C74800
Laboratory Procedure
Bile Acid Measurement
Bile Salts
Bile Acid Measurement
C0523530
CDISC SEND Terminology
HER2/Neu Negative
HER2/Neu Negative
HER2/Neu Negative
owl:Class
Her2/Neu Status
HER2/Neu Negative
C68749
Clinical Attribute
CL374450
Diagnostic Procedure
Colonoscopic Biopsy
Removal of tissue from the colon for microscopic examination, using an endoscope.
owl:Class
C51678
Biopsy of Colon
Biopsy of Colon
Procedure_Has_Partially_Excised_Anatomy only Colon
Biopsy of Colon
Colonoscopy and Biopsy
CL354992
Biopsy of Colon
Endoscopic Biopsy
owl:Class
Chemistry Test
Ionized Calcium Measurement
C81948
The determination of the amount of ionized calcium present in a sample.
Ionized Calcium Measurement
Ionized Calcium Measurement
Ionized Calcium Measurement
Lavage
owl:Class
Irrigation
Lavage
Lavage
Diagnostic Procedure
C38068
Lavage
Diagnostic Procedure
C0022100
Washing out a hollow organ (especially the stomach) by flushing with a fluid.
C15762
Surgical removal of part or all of the colon, using a laparoscope.
Laparoscopic-Assisted Colectomy
<def-source>NCI-GLOSS</def-source><def-definition>Surgery done with the aid of a laparoscope (a thin, lighted tube) to remove part or all of the colon through small incisions made in the wall of the abdomen.</def-definition>
laparoscopic-assisted colectomy
Laparoscopic Colectomy
Laparoscopic Colectomy
Therapeutic or Preventive Procedure
Laparoscopic Colectomy
Laparoscopy-Assisted Colectomy
Colectomy
Therapeutic Laparoscopic Surgery
owl:Class
Laparoscopic Colectomy
CL032899
Activity
CL342356
C48174
Loading
Action
The act of adding a substance or object into something.
owl:Class
Loading
Loading Technique
Loading
Loading
Research Activity
Basic Cancer Research
Breast Cancer-Basic
owl:Class
Breast Cancer, Basic Research
CL003563
Breast Cancer, Basic Research
Breast Cancer, Basic Research
C15957
Research on the molecular, genetic, biochemical, cellular, structural, immunological, pharmacological mechanisms and factors as they relate to the causation, progression, diagnosis, and treatment of breast cancer.
Breast Cancer, Basic Research
Therapeutic or Preventive Procedure
Bronchoscopy
Bronchoscopy
Procedure_Has_Target_Anatomy only Bronchus
C16366
Bronchoscopy
<def-source>NCI-GLOSS</def-source><def-definition>(bron-KOS-ko-pee) A procedure in which a thin, lighted tube is inserted through the nose or mouth. This allows examination of the inside of the trachea and bronchi (air passages that lead to the lung), as well as the lung. Bronchoscopy may be used to detect cancer or to perform some treatment procedures.</def-definition>
C0006290
Endoscopic examination of the tracheobronchial tree.
Diagnostic Procedure
owl:Class
Bronchoscopy
bronchoscopy
Endoscopic Procedure
CL008112
owl:Class
Gene Mapping
A procedure for determining the specific physical locations of genes and markers on each chromosome, using an ordered library of cloned DNA fragments according to their position in the genome, typically with some physically measurable metric, eg, base pairs, kilobases, and megabases.
Laboratory Procedure
Molecular Biology Research Technique
Clone-Based Physical Mapping
Clone-Based Physical Mapping
Clone-Based Physical Mapping
Clone-Based Physical Mapping
C19639
Development and Application of Imaging in Therapeutic Studies
C15946
owl:Class
Technology Development
Development and Application of Imaging in Therapeutic Studies
Development and Application of Imaging in Therapeutic Studies
CL003284
Research Activity
This initiative will encourage applications that apply imaging technologies in the assessment of investigational cancer therapeutic agents. The proposed research projects will focus on the development and application of non-invasive tools for the functional or quantitative assessment of biochemical, genetic, or pharmacologic activity of specific therapeutic agents, or the defined biochemical pathway(s) in which they act. (from an RFA description)
Development and Application of Imaging in Therapeutic Studies
CL384673
Stanazolol Measurement
Stanazolol Measurement
Steroid Measurement
The determination of the amount of stanazolol present in a sample.
Stanazolol Measurement
owl:Class
Laboratory Procedure
C75379
Stanazolol Measurement
Total Pancreatectomy
C15340
Pancreatectomy
C0040511
Total Pancreatectomy
Procedure_Has_Completely_Excised_Anatomy only Pancreas
<def-source>NCI-GLOSS</def-source><def-definition>Surgery to remove the entire pancreas. Part of the stomach, part of the small intestine, the common bile duct, gallbladder, spleen, and nearby lymph nodes also are removed.</def-definition>
Total Pancreatectomy
Therapeutic or Preventive Procedure
Surgical removal of the entire pancreas.
owl:Class
total pancreatectomy
Total Excision of the Pancreas
Total Pancreatectomy
S1 Protection
S1 Protection
owl:Class
C19241
Laboratory Procedure
CL003197
S1 Protection
S1 Protection
RNA Analysis
Molecular biology procedure used to determine the 5' end or 3' end of a nucleic acid molecule, or the location of the junction between spliced molecules. Used most commonly to determine the 5' end of RNA transcripts. Based on the protection afforded an end-labeled DNA probe from nuclease S1 digestion after hybridization with a target molecule. The length of the protected probe indicates the end or molecular junction of the target nucleic acid sequence.
CL322421
Lymphocyte Harvest
Health Care Activity
Lymphocyte Harvest Procedure
Lymphocyte Harvest Procedure
Lymphocyte Harvest Procedure
Harvest Procedure
owl:Class
C38070
Lymphocyte Harvest Procedure
Lymphocyte Harvest; remove lymphocytes from a culture or a living or dead body, as for the purposes of transplantation.
Laboratory Procedure
Quantitative Microscopy
Quantitative Microscopy
C18878
Quantitative Microscopy
owl:Class
Microscopy, Quantitative
Light Microscopy
A microscopy technique comprised of light microscopy coupled with modern microscope optics and use of algorithms for the restoration, segmentation, and analysis of digital images for the quantitative analysis of specimens in order to achieve the accurate measurement of "analog" quantities of a digital representation of an image.
Quantitative Microscopy
CL000548
C51785
CL355291
Excision
owl:Class
Excision of Nerve
Neurectomy
Neurectomy
Therapeutic or Preventive Procedure
Neurectomy
Neurectomy
owl:Class
Diaphranography
Imaging Technique
CL102468
Diaphranography (transillumination light scanning) is a non-invasive imaging procedure for the detection and evaluation of breast disease, by visualizing lesions through a television camera sensitive to infrared light. Diaphranography has been demonstrated to be a useful adjunct to mammography.
Diagnostic Procedure
Diaphranography
C20366
Diaphranography
Diaphranography
C15585
CL030828
Therapeutic or Preventive Procedure
Drug therapy in which the drug is a fusion protein generated by molecular biology procedures. The fusion protein combines a cell targeting moiety, such as an antibody fragment, with an effector moiety, like a bacterial toxin.
Targeted Fusion Protein Therapy
Targeted Fusion Protein Therapy
owl:Class
Targeted Fusion Protein Therapy
Targeted Fusion Protein Therapy
Biological Therapy
owl:Class
Resection of Rectum
Proctectomy
Colon and Rectal Surgery
Procedure_Has_Excised_Anatomy only Rectum
Resection of Rectum
Surgical removal of the rectum.
C51783
Resection of Rectum
Resection of Rectum
Therapeutic or Preventive Procedure
CL356007
CL334080
Data Extraction
A process whereby specific data is taken out of a larger set of data and presented in a usable format.
Activity
Data Extraction
Data Extraction
owl:Class
Data Extraction
C44285
Action
Intubation Procedure
Therapeutic Procedure
Intubation Procedure
owl:Class
C37981
C0021925
The insertion of a cannula or tube into a hollow body organ.
Intubation Procedure
Intubation
Intubation Procedure
Health Care Activity
Display
Instruction Imperative
C25485
Exhibit, present, or demonstrate for viewing.
owl:Class
CL052094
Display
Displayable
Display
Display
Activity
Action
Case Series
owl:Class
Case Series
Case Series
Research Activity
C16229
case series
Case Series
Study Design
CL027394
<def-source>NCI-GLOSS</def-source><def-definition>A group or series of case reports involving patients who were given similar treatment. Reports of case series usually contain detailed information about the individual patients. This includes demographic information (for example, age, gender, ethnic origin) and information on diagnosis, treatment, response to treatment, and follow-up after treatment.</def-definition>
Goal: identify and characterize every major human gene that predisposes people to cancer; begin to apply these discoveries through clinical practice to help patients at risk; address the psychosocial, ethical, and legal issues associated with inherited cancer susceptibility (NCI Web)
Extraordinary Opportunity: Genes and the Environment
C16132
From NCI Priorities Web page: Opportunities now exist to determine how variations in our genes combine with environmental factors to cause cancer.
Extraordinary Opportunity: Genes and the Environment
Research Activity
owl:Class
Extraordinary Opportunity: Genes and the Environment
CL014045
Extraordinary Opportunities for Investment
Extraordinary Opportunity: Genes and the Environment
Vitamin D3 Measurement
Laboratory Procedure
C74905
Vitamin D3 Measurement
Vitamin D3 Measurement
VITD3
<def-definition>A measurement of the Vitamin D3 in a biological specimen.</def-definition><def-source>CDISC</def-source>
The determination of the amount of Vitamin D3 present in a sample.
owl:Class
CDISC SDTM Terminology
Vitamin D3 Measurement
Cholecalciferol
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
Vitamin D3
Vitamin Measurement
C0523979
Therapeutic or Preventive Procedure
CL038722
PUVA Photochemotherapy
PUVA Photochemotherapy
C29973
UVA Light Therapy
owl:Class
PUVA Photochemotherapy
PUVA
PUVA Photochemotherapy
Therapeutic or Preventive Procedure
owl:Class
therapy, high-LET pion
High-LET Pion Therapy
High-LET Pion Therapy
Radiation Therapy
High-LET Pion Therapy
C15459
CL029157
High-LET Pion Therapy
owl:Class
Moderate Exercise
Moderate Exercise
Moderate Exercise
Moderate exercises include basketball, singles tennis, downhill skiing, and moderate walking. Maximum heart rate is approximately 220 minus current age in years.
Moderate Exercise
Exercise
C39772
Daily or Recreational Activity
CL323823
Moderate Activity
20-60 minutes of exercise which elevates your heart rate to 60-80% of your maximum heart rate performed at least 3-4 times per week.
Laboratory Procedure
Drug Class Measurement
Drug Class Measurement
C74675
CL384278
Chemistry Test
Drug Class Measurement
Drug Class Measurement
The determination of the levels of all members of a specific drug class present in a sample.
owl:Class
Individual Behavior
C16575
Ingestive Behavior
Ingestive Behavior
Ingestive Behavior
C0015745
Behavior
<def-source>MSH2001</def-source><def-definition>Behavioral responses or sequences associated with eating including modes of feeding, rhythmic patterns of eating, and time intervals.</def-definition>
Eating habits and their role in human disease
Ingestive Behavior
owl:Class
Diagnostic Procedure
Clinical Breast Examination
Screening Method
An exam of the breast performed by a health care provider to check for lumps or other changes.
owl:Class
Clinical Breast Examination
C0199850
Clinical Breast Examination
Clinical Breast Examination
C70552
Health Care Activity
Group Therapy
Group Therapy
C0033971
Group Therapy
owl:Class
A form of psychiatric treatment in which six to eight patients meet a specific number of times with a therapist. The value of this type of therapy is the opportunity for gaining insight from others into one's life experience. (Taber's)
Group Therapy
C21042
Psychotherapy
owl:Class
Vascular Epithelial Growth Factor Measurement
Vascular Epithelial Growth Factor Measurement
C82043
The determination of the amount of vascular epithelial growth factor present in a sample.
Vascular Epithelial Growth Factor Measurement
Protein or Enzyme Type Measurement
Vascular Epithelial Growth Factor Measurement
Diagnostic Procedure
Intervention or Procedure
endoscopy
Endoscopic Procedure
<def-source>NCI-GLOSS</def-source><def-definition>(en-DAHS-ko-pee) The use of a thin, lighted tube (called an endoscope) to examine the inside of the body.</def-definition>
Therapeutic or Preventive Procedure
C16546
C0014245
Endoscopic Procedure
Endoscopic
<def-source>MSH2001</def-source><def-definition>Endoscopic examination, therapy or surgery performed on interior parts of the body.</def-definition>
Endoscopic Examination
Endoscopy
Endoscopic Procedure
owl:Class
Endoscopic Procedure
Procedure_Has_Target_Anatomy only Organ
Underdose, Radiation
C52354
Radiation Underdose
CL355810
Patient Problem Codes FDA CDRH
Functional Concept
Radiation Underdose
Patient Code (Appendix B)
Radiation Underdose
Underdose
Radiation Underdose
owl:Class
FDA
Fibrinogen Measurement
C64606
CDISC SDTM Laboratory Test Terminology by Name
owl:Class
CDISC SDTM Terminology
CDISC
Fibrinogen
FIBRINO
A quantitative measurement of the amount of fibrinogen present in a sample.
Clinical Data Interchange Standards Consortium Terminology
Fibrinogen Measurement
CDISC SEND Terminology
Fibrinogen Measurement
CDISC SDTM Laboratory Test Terminology by Code
C0337428
Protein or Enzyme Type Measurement
Laboratory Procedure
<def-source>CDISC</def-source><def-definition>A measurement of the fibrinogen in a biological specimen.</def-definition>
Fibrinogen Measurement
C71504
Quantitative Concept
CL378139
Nonrandom Sampling
Quota Sampling
Quota Sampling
Quota Sampling
Quota Sampling
owl:Class
owl:Class
Electroporation Therapy
Therapeutic or Preventive Procedure
<def-source>NCI-GLOSS</def-source><def-definition>Treatment that generates electrical pulses through an electrode placed in a tumor to enhance the ability of anticancer drugs to enter tumor cells.</def-definition>
electroporation therapy
C15707
C0678054
Electroporation Therapy
Electroporation Therapy
EPT
Electroporation Therapy
Therapeutic Procedure
Dental Restoration
Partial Crown
Partial Crown
A dental restoration incompletely covering the aspect of the tooth normally covered by enamel.
Partial Crown
owl:Class
Therapeutic or Preventive Procedure
C66859
CL370963
Partial Crown
RMA Background Correction Method
RMA Background Correction Method
Background Correction Method
Perform RMA background correction. Defined in the documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html.
RMA Background Correction Method
CL369343
Activity
owl:Class
RMA Background Correction Method
C64235
C65170
owl:Class
Statistical Technique
2-norm Distance
Euclidean Distance Measurement
Activity
CL369682
Euclidean Distance
Euclidean Distance Measurement
Euclidean Distance Measurement
A generalization of the Pythagorean theorem to more than two coordinates. It is what would be obtained if the distance between two points were measured with a ruler: the "intuitive" idea of distance.
Euclidean Distance Measurement
Procedure_Has_Target_Anatomy only 'Small Intestine'
Therapeutic or Preventive Procedure
Surgical creation of an external opening into the jejunum.
owl:Class
C79978
Jejunostomy
Procedure_Has_Target_Anatomy only Jejunum
Jejunostomy
Enterostomy
Jejunostomy
Jejunostomy
Endoscopic Retrograde Cholangiopancreatography
C16430
C0008310
Therapeutic or Preventive Procedure
Endoscopic Retrograde Cholangiopancreatography
endoscopic retrograde cholangiopancreatography
Endoscopic Procedure
owl:Class
Endoscopic Retrograde Cholangiopancreatography
Endoscopic Retrograde Cholangiopancreatography
Procedure_Has_Target_Anatomy only 'Pancreatic Duct'
<def-source>NCI-GLOSS</def-source><def-definition>(en-dah-SKAH-pik RET-ro-grade ko-LAN-jee-o-PAN-kree-a-TOG-ra-fee) ERCP. A procedure to x-ray the pancreatic duct, hepatic duct, common bile duct, duodenal papilla, and gallbladder. In this procedure, a thin, lighted tube (endoscope) is passed through the mouth and down into the first part of the small intestine (duodenum). A smaller tube (catheter) is then inserted through the endoscope into the bile and pancreatic ducts. A dye is injected through the catheter into the ducts, and an x-ray is taken.</def-definition>
<def-source>MSH2001</def-source><def-definition>Fiberoptic endoscopy designed for duodenal observation and cannulation of VATER'S AMPULLA, in order to visualize the pancreatic and biliary duct system by retrograde injection of contrast media. Endoscopic (Vater) papillotomy (SPHINCTEROTOMY, ENDOSCOPIC) may be performed during this procedure.</def-definition>
Procedure_Has_Target_Anatomy only 'Bile Duct'
<def-source>NCI-GLOSS</def-source><def-definition>Endoscopic retrograde cholangiopancreatography (en-do-SKAH-pik RET-ro-grade ko-LAN-jee-o-PAN-kree-a-TAW-gra-fee). A procedure to x-ray the pancreatic duct, hepatic duct, common bile duct, duodenal papilla, and gallbladder. In this procedure, a thin, lighted tube (endoscope) is passed through the mouth and down into the first part of the small intestine (duodenum). A smaller tube (catheter) is then inserted through the endoscope into the bile and pancreatic ducts. A dye is injected through the catheter into the ducts, and an x-ray is taken.</def-definition>
ERCP
Diagnostic Procedure
Bioassay, in vitro
Migration Assay
Migration Assays
Migration Assay
Migration Assay
Migration Assay
owl:Class
C19425
An in vitro assay in which cultured cells are monitored and analyzed for their ability to move into an acellular area of a culture material.
Laboratory Procedure
CL004162
Cell Migration Assay
C70824
Clinical Study by Organizational Parameters
Clinical Study by Organizational Parameters
Clinical Study by Organizational Parameters
Clinical Study by Organizational Parameters
Research Activity
Clinical Study
owl:Class
CL375964
Follow-up Study
Follow-up Study
C0016441
Study in which persons exposed to risk or given a designated preventive or therapeutic regimen are observed over a period or at intervals to determine the outcome of the exposure or regimen.
Follow-up Study
Follow-up Study
Research Activity
owl:Class
Clinical Study by Design
C15234
owl:Class
Report Source ICSR Terminology
clinical study
Individual Case Safety Report Terminology
Clinical Study
FDA
Clinical Research
Clinical Study
Research conducted with human subjects or on material of human origin in which an investigator directly interacts with human subjects; includes development of new technologies, study of mechanisms of human diseases, therapy, clinical trials, epidemiologic, behavior, and health services research.
Study
Research Activity
Clinical Study
Clinical Study
C0008972
C15206
Study
Clinical Studies
Alpha Naphthyl Esterase Staining Method
Alpha Naphthyl Acetate Esterase Staining Method
Alpha Naphthyl Acetate Esterase Stain
Alpha Naphthyl Acetate Esterase Staining Method
Alpha Naphthyl Acetate Esterase Staining Method
Laboratory Procedure
A cytochemical staining technique used to detect alpha-naphthyl acetate esterase (ANAE) activity. Nonspecific esterase stains with acetate substrate and is mainly used in the determination of lineage in acute myelogenous leukemia. Acute megakaryoblastic leukemia (M7) blasts stain strongly when the acetate substrate is used.
C28417
Alpha Naphthyl Acetate Esterase Staining Method
Alpha Naphthyl Acetate Esterase Staining Method
owl:Class
C1294078
owl:Class
Experimental Method
Experimental Method
C43622
CL333674
Research Technique
Experimental Method
Experimental Method
The use of controlled observations and measurements to test hypotheses.
Research Activity
C15997
Cessation Research
Cessation Research
Cessation Research
Research Activity
Smoking and Health Research
CL003986
Cessation Research
owl:Class
Sclerotherapy
Sclerotherapy
Sclerotherapy
Therapeutic or Preventive Procedure
Therapeutic Procedure
owl:Class
C0036435
Sclerotherapy
C62732
C64201
To analyze computer data such as control statements embedded in a program, and take appropriate action before processing the data.
Preprocess
Preprocess
Preprocess
Computational Technique
CL369123
owl:Class
Machine Activity
Preprocess
Trichrome
owl:Class
Masson trichrome, a mixture of three dyes, is used to differentiate between collagen and smooth muscle in tumors, and increases in collagen in cirrhosis. The three dyes used are aniline blue that stains collagen and mucus to blue or blue green, the cytoplasm and muscle and keratin are stained red by Beibrich Scarlet and nuclei are stained blue to black with Weigert's Iron hematoxylin (From BioGenex).
TRIC
C1318478
Laboratory Procedure
Special Histology Staining Method
Trichrome Staining Method
Trichrome Staining Method
Trichrome Staining Method
Trichrome Staining Method
Trichrome Staining Method
C23012
C16092
Research Activity
Goal: refine current models, create models that more closely parallel human cancers, devise efficient procedures that will make models available to all researchers who need them. (NCI Web)
Extraordinary Opportunity: Preclinical Models of Cancer
owl:Class
CL008667
Extraordinary Opportunities for Investment
Extraordinary Opportunity: Preclinical Models of Cancer
Extraordinary Opportunity: Preclinical Models of Cancer
Extraordinary Opportunity: Preclinical Models of Cancer
C0024671
C16818
A type of radiography used specifically to examine breast tissue. The procedure utilizes a low-dose of x-rays or radiation to generate an image. A mammography exam or mammogram, is used as a screening tool to detect early breast cancer in women experiencing no symptoms and to detect and diagnose breast disease.
Diagnostic Procedure
Mammography
<def-source>NCI-GLOSS</def-source><def-definition>(mam-OG-ra-fee) The use of x-rays to create a picture of the breast.</def-definition>
Radiography
owl:Class
Mammography
mammography
Mammography
Mammography
Laboratory Procedure
Radioimmunoassay (RIA) is an immunological technique, which quantitatively determines antigen and antibody concentrations, using a radioactively labeled substance (radioligand), either directly or indirectly.
Immunologic, Radioimmunoassay
Immunology Test
C17057
Radioimmunoassay
Radioimmunoassay
C0034580
Radioimmunoassay
Radioimmunoassay
owl:Class
C53349
CL356334
owl:Class
Population-Based Statistic
Observed Incidence
Observed Incidence
Quantitative Concept
Observed Incidence
Observed Incidence
owl:Class
C53238
Parametric Regression Method
CL356501
Parametric Regression Method
Regression analysis provides a "best-fit" mathematical equation for the relationship between the dependent variable (response) and independent variable(s) (covariates). Parametric regression requires choice of the regression equation with one or a greater number of unknown parameters. The aim of parametric regression is to find the values of these parameters which provide the best fit to the data. The number of parameters is usually much smaller than the number of data points.
Parametric Regression Method
Parametric Regression Method
Quantitative Concept
Regression Method
Supportive Care
C62738
Dermatologic Complications Management
Therapeutic or Preventive Procedure
Dermatologic Complications Management
Dermatologic Complications Management
CL035528
Dermatologic Complications Management
owl:Class
Anatomic Pathology Procedure
Laboratory Procedure
Laboratory Procedure
Anatomic Pathology Procedure
Anatomic Pathology Procedure
C74942
C0200712
A laboratory procedure that involves the examination of tissues or cells for diagnostic or research purposes.
owl:Class
Anatomic Pathology Procedure
Image Guided Biopsy
Mammotome
A minimally invasive biopsy system that uses either sterotactic mammography or ultrasound for precise positioning of a vacuum-assisted biopsy probe.
C47949
Diagnostic Procedure
Vacuum-Assisted Biopsy
Vacuum-Assisted Biopsy
CL343206
Vacuum-Assisted Biopsy
owl:Class
Vacuum-Assisted Biopsy
Needle Biopsy
The use of molecular tools and techniques, especially gene and protein expression profiles, to diagnose disease.
owl:Class
C20826
Molecular Diagnosis
Diagnosis
Molecular Diagnosis
CL028309
Diagnostic Procedure
Molecular Diagnosis
Molecular Diagnosis
owl:Class
Therapeutic or Preventive Procedure
<def-source>NCI-GLOSS</def-source><def-definition>(an-es-THEE-zha) Drugs or substances that cause loss of feeling or awareness. Local anesthetics cause loss of feeling in a part of the body. General anesthetics put the person to sleep.</def-definition>
C0002903
C15181
Treatment with a pharmacological substance that produces a loss of feeling.
Anesthesia Procedure
Newborn Screening
Pre-Procedure Preparation
Anesthesia Procedure
Anesthesia Procedure
Anesthesia
Anesthesia Procedure
anesthesia
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Name
C74612
Hypersegmented Neutrophil Measurement
owl:Class
<def-source>CDISC</def-source><def-definition>A measurement of the hypersegmented (more than five lobes) neutrophils in a biological specimen.</def-definition>
Hypersegmented Cells
HYPSEGCE
CDISC SDTM Laboratory Test Terminology by Code
CL384405
Laboratory Procedure
Hypersegmented Neutrophil Measurement
CDISC
Clinical Data Interchange Standards Consortium Terminology
Neutrophil Count
Hypersegmented Neutrophil Measurement
Hypersegmented Neutrophil Measurement
The determination of the number of hypersegmented neutrophils present in a sample.
CDISC SDTM Terminology
CL354500
C49503
owl:Class
CDISC SDTM Terminology
Activity
CDISC SDTM Action Taken with Study Treatment Terminology
Dose Increased
<def-source>CDISC</def-source><def-definition>An indication that a medication schedule was modified by addition; either by changing the frequency, strength or amount. (NCI)</def-definition>
CDISC
Action Taken with Study Treatment
Dose Increased
DOSE INCREASED
An indication that a medication schedule was modified by addition; either by changing the frequency, strength or amount.
Dose Increased
Dose Increased
Clinical Data Interchange Standards Consortium Terminology
Immunohistochemistry Staining Method
Cell/Tissue, Immunohistochemistry
Immunohistochemistry Staining Method
C23020
CL100939
Immunohistochemistry Staining Method
Immunohistochemical staining techniques allow for the visualization of antigens via the sequential application of a specific antibody to the antigen (primary antibody), a secondary antibody to the primary antibody and an enzyme complex with a chromogenic substrate. The enzymatic activation of the chromogen results in a visible reaction product at the antigen site. The specimen may then be counterstained and coverslipped. Results are interpreted using a light microscope and aid in the differential diagnosis of pathophysiological processes, which may or may not be associated with a particular antigen.
Laboratory Procedure
Immunohistochemistry Staining Method
Immunohistochemistry Staining Method
IHC
owl:Class
Special Histology Staining Method
Immunohistochemistry
Pharmacotherapy
Preemptive Analgesia
Preemptive Analgesia
C21093
Preemptive Analgesia
Preemptive Analgesia
Treatment with analgesics on a schedule or in advance of the return of pain in an attempt to minimize peaks in the pain cycle.
owl:Class
Therapeutic or Preventive Procedure
CL102846
<def-source>CDISC</def-source><def-definition>A measurement of the fine granular casts present in a urine specimen.</def-definition>
The determination of the amount of fine granular casts present in a urine sample.
Granular Fine Cast Measurement
Clinical Data Interchange Standards Consortium Terminology
owl:Class
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Laboratory Test Terminology by Code
Laboratory Procedure
Granular Fine Cast Measurement
Granular Fine Casts
Urine Sediment Analysis Measurement
Granular Fine Cast Measurement
CDISC SDTM Terminology
C74769
CSGRANF
Granular Fine Cast Measurement
CL384718
CDISC
Fine Granular Cast Measurement
Personal Communication
C0086792
Personal Communication
Social Behavior
Personal Communication
Interpersonal Communication
The exchange of information between people. Often used as a citation when information is passed from one researcher to another, but is not published.
Communication
Personal Communication
owl:Class
C17465
CL029091
Somatostatin Analog Therapy
C15449
Somatostatin Analog Therapy
Endocrine Drug Therapy
Somatostatin Analog Therapy
Therapeutic or Preventive Procedure
Somatostatin Analog Therapy
Somatostatin Analogue Therapy
owl:Class
Expression Technologies for DNA and RNA
C19132
Expression Technologies for DNA and RNA
CL001119
owl:Class
Molecular Biology Research Technique
Molecular Genetic Technique
Expression Technologies for DNA and RNA
Technologies to induce the process of transcription of specific information embodied in the DNA into mRNA (messenger RNA), which is then translated into proteins.
Expression Technologies for DNA and RNA
Smoking Cessation Intervention
owl:Class
Smoking Cessation Intervention
Preventive Intervention
Smoking and Tobacco Use Cessation Interventions
C15372
C1273715
Behavioral Intervention
Therapeutic or Preventive Procedure
Smoking Cessation Intervention
Smoking Cessation Intervention
Carcinoembryonic Antigen Measurement
Immunology Test
C81983
The determination of the amount of carcinoembryonic antigen present in a sample.
Carcinoembryonic Antigen Measurement
Carcinoembryonic Antigen Measurement
owl:Class
Carcinoembryonic Antigen Measurement
Therapeutic or Preventive Procedure
Radiation Therapy
High-LET Heavy Ion Therapy
High-LET Heavy Ion Therapy
High-LET Heavy Ion Therapy
High-LET Heavy Ion Therapy
Therapy, High-LET Heavy Ion
C0279017
owl:Class
Heavy Ion Radiation
C15458
C15210
owl:Class
colon and rectum surgery
Colon and Rectal Surgery
Colon and Rectal Surgery
C0009369
Colon and Rectal Surgery
Colon and Rectal Surgery
colorectal surgery
Abdominal Surgical Procedure
Intestine Resection
Therapeutic or Preventive Procedure
Low-LET Photon Therapy
Therapeutic or Preventive Procedure
owl:Class
Low-LET Photon Therapy
C15444
Low-LET Photon Therapy
therapy, low-LET photon
Low-LET Photon Therapy
CL029005
Radiation Therapy
Cryopreservation
Cryopreserved
C0010405
Cryopreservation
C16475
owl:Class
Biologic Sample Preservation Procedure
Cryopreservation
Laboratory Procedure
Preservation of cells, tissues, organs, or embryos by storage at low temperatures.
Cryopreservation
Activity
Li Wong Probe Summary Method
Bioconductor caAffy Li Wong Probe Summary Method
Probe Summary Method
Bioconductor caAffy Li Wong Probe Summary Method
C64223
Summarizes probe sets using the model described in Li and Wong (2001) to a probe set with I chips and J probes. Defined in the documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html
CL369066
Bioconductor caAffy Li Wong Probe Summary Method
Li Wong
Bioconductor caAffy Li Wong Probe Summary Method
owl:Class
C80205
Resistin Measurement
Resistin Measurement
owl:Class
Laboratory Procedure
Protein or Enzyme Type Measurement
The determination of the amount of resistin present in a sample.
Resistin Measurement
Resistin Measurement
CL102257
Finding
owl:Class
Effectiveness of Interventions
Clinical Testing
Effectiveness of Interventions
Effectiveness of Interventions
Effectiveness of Interventions
C15932
Activity
CL371414
Do Not Interchange
Do Not Interchange
owl:Class
Instruction Imperative
Do Not Interchange
C67007
Do Not Interchange
C20698
Early Detection
Breast Cancer Early Detection
Breast Cancer Early Detection
Diagnostic Procedure
CL027942
Breast Cancer Early Detection
owl:Class
Early Detection of Breast Cancer
Breast Cancer Early Detection
Use of a device, marker, or other means for the purpose of detecting the presence of a breast tumor early in its development.
CEA Assay
owl:Class
Carcinoembryonic Antigen Assay
Diagnostic Procedure
<def-source>NCI-GLOSS</def-source><def-definition>A laboratory test to measure carcinoembryonic antigen (CEA), a substance that is sometimes found in an increased amount in the blood of people who have certain cancers.</def-definition>
CEA assay
CEA Assay
A laboratory blood test to measure carcinoembryonic antigen (CEA), a protein found in many types of cells, but is associated with tumors. Used as a tumor marker.
CEA Assay
CL017831
C20127
Laboratory Procedure
CEA Assay
Protein or Enzyme Type Measurement
Regional Lymph Node Dissection
owl:Class
CL031805
Procedure_Has_Excised_Anatomy only 'Axillary Lymph Node'
Axillary Node Dissection
Axillary Lymph Node Dissection
Axillary Lymph Node Dissection
Axillary Lymph Node Dissection
C15677
axillary dissection
Axillary Lymphadenectomy
Axillary Lymph Node Dissection
Axillary Dissection
Diagnostic Procedure
axillary lymph node dissection
Surgical removal of the lymph nodes located in the cavity beneath the junction of the arm and the thorax, or axilla (armpit). This procedure is commonly performed as a component of cancer staging.
<def-source>NCI-GLOSS</def-source><def-definition>(AK-sil-air-ee) Surgery to remove lymph nodes found in the armpit region.</def-definition>
Therapeutic or Preventive Procedure
Excision Axillary Lymph Nodes
Preventative Nutritional Supplementation
Preventive Intervention
Preventative Nutritional Supplementation
C64894
Therapeutic or Preventive Procedure
owl:Class
Nutritional Supplementation
Preventative Nutritional Supplementation
CL370340
Preventative Nutritional Supplementation
C70911
The conversion of one cardiac rhythm or electrical pattern to another, almost always from an abnormal to a normal one, by pharmacologic means using medications or by electrical cardioversion using a defibrillator.
Cardioversion
owl:Class
C0013778
Therapeutic or Preventive Procedure
Cardiac Therapeutic Procedure
Cardioversion
Cardioversion
Cardioversion
Barbiturate Drug Class Measurement
Secobarbital Measurement
C0202464
The determination of the amount of secobarbital present in a sample.
Laboratory Procedure
C75369
Secobarbital Measurement
Secobarbital Measurement
Secobarbital Measurement
owl:Class
Infusion Technique
Continuous Infusion Procedure
Continuous Infusion Procedure
C15648
<def-source>NCI-GLOSS</def-source><def-definition>The administration of a fluid into a blood vessel, usually over a prolonged period of time.</def-definition>
Continuous Infusion Procedure
Therapeutic or Preventive Procedure
Continuous Infusion
Continuous Infusion Procedure
C0444889
owl:Class
continuous infusion
CDISC SDTM Terminology
2B
<def-definition>A clinical research protocol generally referred to as a well-controlled and pivotal trial that aims to prove the mechanism of action of the new intervention in question. A pivotal study will generally be well-controlled, randomized, of adequate size, and whenever possible, double-blind. (NCI)</def-definition><def-source>CDISC</def-source>
Trial Phase IIB
Phase IIb Trial
Clinical Data Interchange Standards Consortium Terminology
Trial Phase 2B
Phase IIb Trial
CL356224
Phase IIb Trial
Research Activity
Phase II Trial
owl:Class
CDISC SDTM Trial Phase Terminology
Phase IIb Trial
C49688
CDISC
A clinical research protocol generally referred to as a well-controlled and pivotal trial that aims to prove the mechanism of action of the new intervention in question. A pivotal study will generally be well-controlled, randomized, of adequate size, and whenever possible, double-blind.
owl:Class
A standardized series of measurements that assesses the cognitive, motor, and behavioral development in infants and babies from one to twenty-four months of age.
C81232
Bayley Scales of Infant Development
Bayley Scales of Infant Development
Bayley Scales of Infant Development
Infant Screening
Newborn Screening
Bayley Scales of Infant Development
Diagnostic Procedure
Growth Hormone Measurement
Growth Hormone Measurement
CL384636
Laboratory Procedure
Growth Hormone Measurement
C75386
Growth Hormone Measurement
owl:Class
Peptide Hormone Measurement
The determination of the amount of growth hormone (GH) present in a sample.
Reiki Therapy
Health Care Activity
owl:Class
Reiki Therapy
Reiki Therapy
An alternative medical practice. The practitioners of reiki believe that health and disease are a matter of the life force being disrupted. Reiki healers claim to channel reiki into "diseased" individuals for "rebalancing." (from Skeptic's Dictionary)
Biofield Therapy
C15728
Reiki
Reiki Therapy
C0751715
Supraglottic Laryngectomy
Supraglottic Laryngectomy
Procedure_Has_Partially_Excised_Anatomy only Larynx
C51889
owl:Class
CL356077
Surgical removal of the portion of the larynx superior to the true vocal cords.
Therapeutic or Preventive Procedure
Supraglottic Laryngectomy
Supraglottic Laryngectomy
Laryngectomy
owl:Class
Laboratory Procedure
Molecular Biology Research Technique
Chromosome Painting
Refers to the hybridization of fluorescently labeled, chromosome-specific, composite probe pools to cytological preparations. It allows the visualization of individual chromosomes in metaphase or interphase cells and the identification of both numerical and structural chromosomal aberrations with high sensitivity and specificity. Chromosome painting can be applied to cross-species comparisons as well as to the study of chromosomal rearrangements. The simultaneous hybridization of multiple chromosome painting probes, each tagged with a specific fluorochrome or fluorochrome combination, has resulted in the differential color display of chromosomes, i.e. spectral or color karyotyping. (From Ried et al 1998 Hum Mol Genet 7:1619)
Chromosome Painting
C0600509
Fluorescence in situ Hybridization
Chromosome Painting
C18154
Chromosome Painting
Simple Excision of Nasal Polyps
Therapeutic or Preventive Procedure
Simple Excision of Nasal Polyps
Excision
owl:Class
Simple Excision of Nasal Polyps
C51890
CL353674
Simple Excision of Nasal Polyps
Hemoglobin
CDISC SDTM Laboratory Test Terminology by Code
Hemoglobin Measurement
Hemoglobin Measurement
Laboratory Procedure
Newborn Screening
HGB
owl:Class
CDISC SEND Terminology
Clinical Data Interchange Standards Consortium Terminology
Hemoglobin Measurement
CDISC SDTM Laboratory Test Terminology by Name
CDISC
Hemoglobin Measurement
CDISC SDTM Terminology
C0518015
Hematology Test
Protein or Enzyme Type Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the hemoglobin in a biological specimen.</def-definition>
A quantitative measurement of the amount of hemoglobin present in a sample.
C64848
Lumpectomy
Therapeutic or Preventive Procedure
Partial Mastectomy
<def-source>NCI-GLOSS</def-source><def-definition>The removal of a cancer as well as some of the breast tissue around the tumor and the lining over the chest muscles below the tumor. Usually some of the lymph nodes under the arm are also taken out. Also called segmental mastectomy.</def-definition>
lumpectomy
Breast Conservation Treatment
<def-source>NCI-GLOSS</def-source><def-definition>(lump-EK-toe-mee) Surgery to remove the tumor and a small amount of normal tissue around it.</def-definition>
C0851238
Lumpectomy
Lumpectomy
C15755
Lumpectomy
partial mastectomy
Lumpectomy of Breast
owl:Class
Plasma Cell Labeling Index
CL384421
Plasma Cell Labeling Index
Diagnostic Procedure
Plasma Cell Labeling Index
PCLI
Hematology Test
Plasma Cell Labeling Index
Labeling Index
owl:Class
Any of various techniques for determining the s-phase fraction of bone marrow plasma cells. Traditionally, this test has been performed as a two color immunofluorescent microscope technique.
C74934
Laboratory Procedure
Population Based Study
CL356339
Research Activity
Population Based Study
Population Based Study
Study Design
owl:Class
Population Based Study
C53307
Transurethral Prostatectomy
Procedure_Has_Completely_Excised_Anatomy only 'Prostatic Urethra'
TURP
Transurethral Resection
Therapeutic or Preventive Procedure
C0040771
Transurethral Prostatic Resection
Prostate Transurethral Resection
Resection of the prostate using a cystoscope passed through the urethra.
Transurethral Prostatic Resection
Procedure_Has_Partially_Excised_Anatomy only 'Prostate Gland'
Transurethral Prostatic Resection
owl:Class
C15343
<def-source>NCI-GLOSS</def-source><def-definition>(TRANZ-yoo-REE-thral ree-SEK-shun) Surgical procedure to remove tissue from the prostate using an instrument inserted through the urethra.</def-definition>
Transurethral Resection of the Prostate
Prostatectomy
Transurethral Resection of Prostate
transurethral resection of the prostate
Transurethral Prostatic Resection
Gynecological Surgical Procedure
Salpingectomy
C51605
Surgery to remove part or all of the fallopian tube(s).
Salpingectomy
CL354207
Salpingectomy
owl:Class
Procedure_Has_Excised_Anatomy only 'Fallopian Tube'
Therapeutic or Preventive Procedure
Tubal Excision
Salpingectomy
owl:Class
The determination of the amount of antithrombin present in a sample.
Antithrombin Measurement
C81958
Coagulation Study
Antithrombin Measurement
Antithrombin Measurement
Antithrombin Measurement
CL319746
Id MM Vaccine Test
Id MM Skin Test
Id MM Vaccine Test
Skin Test
Id MM Vaccine Test
Diagnostic Procedure
A test consisting of a myeloma idiotype (Id)-specific protein conjugated to the immunogen keyhole limpet hemocyanin (KLH). As a test of innate host delayed-type hypersensitivity (DTH) and host DTH in response to therapeutic vaccination, Id MM vaccine test is performed intradermally before and after therapeutic vaccination in multiple myeloma patients treated with Id-specific vaccines. (NCI04)
C29111
659643
owl:Class
Id MM Vaccine Test
Therapeutic or Preventive Procedure
Procedure_Has_Target_Anatomy only Trachea
CL054755
owl:Class
Tracheoesophageal Puncture
Tracheoesophageal Puncture
Tracheoesophageal Puncture
Procedure_Has_Target_Anatomy only Esophagus
Tracheoesophageal Puncture
tracheoesophageal puncture
C15915
Digestive System Surgery
<def-source>NCI-GLOSS</def-source><def-definition>(TRAY-kee-o-eh-SOF-uh-JEE-al PUNK-chur) A small opening made by a surgeon between the esophagus and the trachea. A valve keeps food out of the trachea but lets air into the esophagus for esophageal speech.</def-definition>
Amputation of Penis
Urogenital Surgical Procedure
Amputation of Penis
The surgical removal of the penis.
Penectomy
C0194708
Procedure_Has_Excised_Anatomy only Penis
Amputation of Penis
C51621
Amputation
owl:Class
Amputation of Penis
Therapeutic or Preventive Procedure
Health Care Activity
Therapy Preparation
Harvest Procedure
Harvest
CL322379
Harvest Procedure
owl:Class
Remove from a culture or a living or dead body, as for the purposes of transplantation.
C37963
Harvest Procedure
Harvest Procedure
Special Histology Staining Method
owl:Class
C1512414
Her2/erbb2/neu Staining Method
C23036
Neu Staining Method
her2/erbb2/neu
A immunohistochemical technique to identify ErbB2/Neu gene, which encodes for 185-kDa member of the ErbB family of cell surface receptor tyrosine kinases. This family of growth factor receptors is comprised of four members: epidermal growth factor receptor (also termed ErbB1/HER1), ErbB2/Neu/HER2/p185, ErbB3/HER3, and ErbB4/HER4. Activation of the ErbB family of growth factor receptors and subsequent stimulation of their associated intracellular signaling pathways is a significant factor in the genesis of several human cancers. The technique is used in diagnostic histopathology to identify breast cancer.
Laboratory Procedure
Her2/erbb2/neu Staining Method
Her2/erbb2/neu Staining Method
neu
Her2/erbb2/neu Staining Method
Her2/erbb2/neu Staining Method
CNEU
ERBB
Arterial Phase Spiral CT
Diagnostic Procedure
C19910
owl:Class
CL009736
A type of computed tomography in which images are taken during the time when the contrast medium has passed the heart and entered the arteries.
Arterial Phase Spiral CT
Arterial Phase Spiral CT
Arterial Phase Spiral CT
Phased Spiral CT
Normalized Quotient
Normalized Quotient
CL357310
Normalized Quotient
Laboratory Procedure
Normalized Quotient
C54569
Following amplification of reverse transcriptase polymerase chain reaction assay, the quantified amount of the target gene divided by the quantified amount of housekeeping gene.
DNA Analysis
owl:Class
C69308
owl:Class
Therapeutic or Preventive Procedure
Therapeutic Procedure
Receptor Antagonist Therapy
Receptor Antagonist Therapy
CL375407
Receptor Antagonist Therapy
Receptor Antagonist Therapy
Biopsy
Bladder Biopsy
Biopsy of Bladder
Diagnostic Procedure
Biopsy of Bladder
Biopsy of Bladder
Biopsy of Bladder
C51700
owl:Class
Procedure_Has_Partially_Excised_Anatomy only Bladder
Removal of tissue from the bladder for microscopic examination.
CL354990
The use of drugs to protect nerve cells from damage by cancer therapy agents.
Chemoprotection
C15662
Therapeutic or Preventive Procedure
C0598958
owl:Class
Neuroprotection
Neuroprotection
Neuroprotection
Neuroprotection
Molecular Function
<def-source>NCI-GLOSS</def-source><def-definition>(trans-plan-TAY-shun) A procedure to replace bone marrow destroyed by treatment with high doses of anticancer drugs or radiation.</def-definition>
Bone Marrow Transplantation
Bone Marrow Grafting
Bone Marrow Transplantation
Marrow Transplantation
Bone Marrow Transplantation
Transplantation
BMT
C15194
C0005961
owl:Class
Bone Marrow Transplant
bone marrow transplantation
Therapeutic or Preventive Procedure
A procedure to replace diseased or pathologic bone marrow with transplanted healthy bone marrow cells.
Bone Marrow Transplantation
A technique that uses X-ray film to visualize gross anatomical structures that have been radioactively labeled.
owl:Class
Autoradiography, Gross
Autoradiography
Autoradiography, Gross
Autoradiography, Gross
C19231
Autoradiography, Gross
CL003146
Gross Autoradiography
Diagnostic Procedure
Diagnostic Surgical Procedure
Surgical Procedure
owl:Class
C64979
Diagnostic Surgical Procedure
Diagnostic Procedure
C0522769
Diagnostic Surgical Procedure
Diagnostic Surgical Procedure
Diagnostic Procedure
owl:Class
Instruction Imperative
Mix
CL370473
Mix
C64925
Activity
To bring or combine together or with something else; add as an additional element or part.
Mix
Mix
owl:Class
Risk Reduction
Individual Behavior
C19694
Risk Reduction
Risk Reduction
Risk Reduction
CL008530
Personal Behavior
Calcium Phosphate Crystal Measurement
Crystal Growth Measurement
CDISC
Laboratory Procedure
<def-source>CDISC</def-source><def-definition>A measurement of the calcium phosphate crystals present in a biological specimen.</def-definition>
C74671
Calcium Phosphate Crystals
CDISC SDTM Laboratory Test Terminology by Code
CDISC SEND Terminology
Calcium Phosphate Crystal Measurement
The determination of the amount of calcium phosphate crystals present in a sample.
CL384770
Calcium Phosphate Crystal Measurement
Calcium Phosphate Crystal Measurement
owl:Class
CDISC SDTM Laboratory Test Terminology by Name
CYCAPHOS
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
The determination of the amount of amorphous sediment present in a sample.
Amorphous Sediment Measurement
AMORPHSD
Clinical Data Interchange Standards Consortium Terminology
Amorphous Sediment Measurement
Amorphous Sediment Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the amorphous sediment present in a biological specimen.</def-definition>
CDISC SDTM Terminology
Chemistry Test
Laboratory Procedure
CDISC SEND Terminology
Amorphous Sediment
Amorphous Sediment Measurement
owl:Class
C74666
CL384271
CDISC
CDISC SDTM Laboratory Test Terminology by Name
General term for hemodialysis, plasmapheresis, blood transfusions, and related procedures involving autologous removal, alteration, and replacement of patients' blood or blood components.
Blood Treatment
Blood Treatment
Blood Treatment
C0596197
Therapeutic Procedure
Therapeutic or Preventive Procedure
C15657
Blood Treatment
owl:Class
Vitamin B7 Measurement
C74902
Vitamin B7 Measurement
The determination of the amount of Vitamin B7 present in a sample.
<def-definition>A measurement of the Vitamin B7 in a biological specimen.</def-definition><def-source>CDISC</def-source>
Vitamin B7 Measurement
Laboratory Procedure
CDISC SDTM Terminology
Biotin
Vitamin Measurement
VITB7
Clinical Data Interchange Standards Consortium Terminology
Vitamin B7 Measurement
CDISC SEND Terminology
CL384442
CDISC SDTM Laboratory Test Terminology by Code
owl:Class
Vitamin B7
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
C80273
Mutation Analysis
BRAF V600E Mutation Analysis
owl:Class
BRAF V600E Mutation Analysis
BRAF V600E Mutation Analysis
BRAF V600E Mutation Analysis
CL369326
Baseline Removal Method
Mean Baseline Removal Method
owl:Class
C64239
Mean Baseline Removal Method
Method for identifying invariant set normalization baseline using mean expression values. Defined in the documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html.
Activity
Mean Baseline Removal Method
Mean Baseline Removal Method
Deoxypyridinoline Measurement
owl:Class
Protein or Enzyme Type Measurement
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
Laboratory Procedure
Deoxypyridinoline Measurement
Deoxypyridinoline Measurement
Deoxypyridinoline
<def-definition>A measurement of the deoxypyridinoline in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Laboratory Test Terminology by Code
C79443
Deoxypyridinoline Measurement
Clinical Data Interchange Standards Consortium Terminology
DPD
CDISC SDTM Terminology
The determination of the amount of deoxypyridinoline present in a sample.
CL374330
Inoculation
Action
To implant microbes or infective materials, introduce immune serum, vaccines of various kinds, and other antigenic materials for preventive, curative, or experimental purposes.
owl:Class
Inoculation
Inoculation
C68774
Activity
Inoculation
Immunoenzyme Procedure
Immunoenzyme Procedure
Immunoenzyme Procedure
Immunoenzyme Procedure
Immunology Test
C16714
An immunological procedure used for the microscopic examination of tissues. It involves the usage of enzyme-antibody or enzyme-antigen conjugates, antienzyme antibodies, or enzyme-antienzyme complexes.
Laboratory Procedure
CL384406
Diagnostic Procedure
owl:Class
Glucose Tolerance Test
Diagnostic Procedure
C0017741
Glucose Tolerance Test
C45946
Glucose Tolerance Test
Laboratory Procedure
Glucose Tolerance Test
owl:Class
A test that involves administration of a know quantity of glucose as a means of screening for glucose intolerance or diabetes mellitus. Typically a baseline (fasting plasma or serum glucose) is drawn prior to the administration of the glucose bolus. Serial plasma glucose levels are obtained (e.g. 30min, 1hr, 2hr, 3hr) and a plot of plasma glucose versus time is created. Comparison of these values against standardized results can be used in establishing the diagnosis of glucose intolerance or diabetes mellitus.
Laboratory Procedure
CNS Depressant Drug Measurement
Ethanol Measurement
Clinical Data Interchange Standards Consortium Terminology
CDISC SEND Terminology
Ethanol Measurement
CDISC SDTM Laboratory Test Terminology by Name
Ethanol Measurement
C74693
C0202304
Ethanol Measurement
The determination of the amount of ethanol present in a sample.
Alcohol
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Terminology
owl:Class
Ethanol
<def-definition>A measurement of the ethanol present in a biological specimen.</def-definition><def-source>CDISC</def-source>
ETHANOL
Nonrandom Sampling
owl:Class
C71502
Nonrandom Sampling
Sampling Method
Nonrandom Sampling
CL378126
Nonrandom Sampling
Quantitative Concept
Vascular Cell Adhesion Molecule 1 Measurement
owl:Class
The determination of the amount of vascular cell adhesion molecule 1 present in a sample.
Vascular Cell Adhesion Molecule 1 Measurement
Protein or Enzyme Type Measurement
Vascular Cell Adhesion Molecule 1 Measurement
Vascular Cell Adhesion Molecule 1 Measurement
C82042
owl:Class
C0009586
Planned, non-emergency care that includes prevention and maintance and restoration of health.
Patient Care
Comprehensive Care
Health Care Activity
Comprehensive Care
C52640
Comprehensive Care
Comprehensive Care
C16109
Preclinical Testing
CL102247
Preclinical Testing
Research Activity
Preclinical Testing
Preclinical Testing
Testing
owl:Class
Wilcoxon-Mann-Whitney U Test
Mann-Whitney Test
Wilcoxon Ranked Sum Test
CL356689
Non-Parametric Test
Mann-Whitney Test
The Wilcoxon-Mann-Whitney test uses the ranks of data to test the hypothesis that two samples of sizes m and n might come from the same population.
Quantitative Concept
owl:Class
Mann-Whitney Test
Mann-Whitney Test
C53247
owl:Class
Douche
Therapeutic or Preventive Procedure
Douche
C15374
CL330103
Therapeutic Procedure
Douche
douche
Douche
<def-source>NCI-GLOSS</def-source><def-definition>(DOOSH) A procedure in which water or a medicated solution is used to clean the vagina and cervix.</def-definition>
owl:Class
CL353067
C48906
The act of requesting that person, business, or organization supply something in return for payment.
Order
Ordered
Activity
Order
Order
Action
Order
Spearman Rank-Order Correlation
A distribution-free analog of correlation analysis. Like regression, it can be applied to compare two independent random variables, each at several levels (which may be discrete or continuous). Unlike regression, Spearman's rank correlation works on ranked (relative) data, rather than directly on the data itself.
Spearman Rank-Order Correlation
Activity
owl:Class
Statistical Technique
C65171
CL371319
Spearman Rank-Order Correlation
Spearman Rank-Order Correlation
Matrix Metalloproteinase 3 Measurement
The determination of the amount of matrix metalloproteinase 3 present in a sample.
Protein or Enzyme Type Measurement
owl:Class
C80194
Laboratory Procedure
Matrix Metalloproteinase 3 Measurement
Matrix Metalloproteinase 3 Measurement
Matrix Metalloproteinase 3 Measurement
CL356073
owl:Class
Subtotal Gastrectomy
Surgical removal of part of the stomach.
Therapeutic or Preventive Procedure
Subtotal Gastrectomy
Procedure_Has_Partially_Excised_Anatomy only Stomach
Subtotal Gastrectomy
Gastrectomy
Subtotal Gastrectomy
C51583
Osteocalcin Measurement
Laboratory Procedure
<def-source>CDISC</def-source><def-definition>A measurement of the osteocalcin in a biological specimen.</def-definition>
CDISC SEND Terminology
CDISC SDTM Terminology
OSTEOC
Osteocalcin Measurement
Osteocalcin Measurement
Protein or Enzyme Type Measurement
CDISC SDTM Laboratory Test Terminology by Name
Osteocalcin Measurement
CDISC
C74744
The determination of the amount of osteocalcin present in a sample.
C0373691
Osteocalcin
owl:Class
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
owl:Class
Granulocyte Macrophage Colony Stm Factor Measurement
Granulocyte Macrophage Colony Stm Factor Measurement
The determination of the amount of granulocyte macrophage colony stimulating factor present in a sample.
Granulocyte Macrophage Colony Stm Factor Measurement
C82019
Protein or Enzyme Type Measurement
Granulocyte Macrophage Colony Stm Factor Measurement
Therapeutic or Preventive Procedure
Lateral Condensation
Lateral Condensation
CL371183
Endodontic Treatment
C66856
Lateral Condensation
Lateral Condensation
An endodontic filling technique which compresses the filling material, gutta percha, parallel to the long tooth axis in the root canal.
owl:Class
owl:Class
Administration of an agent within 30 days of a specified date.
CL357660
Agent Given Within 30 Days
C54063
Agent Given Within 30 Days
Prior Therapy
Agent Given Within 30 Days
Agent Given Within 30 Days
Clinical Attribute
Therapeutic or Preventive Procedure
Neck Dissection
Modified Radical Neck Dissection
Modified Radical Neck Dissection
Modified Radical Neck Dissection
Procedure_May_Have_Partially_Excised_Anatomy some 'Sternocleidomastoid Muscle'
C51904
CL354098
Procedure_May_Have_Completely_Excised_Anatomy some 'Submandibular Gland'
Procedure_May_Have_Partially_Excised_Anatomy some 'Internal Jugular Vein'
owl:Class
Modified Radical Neck Dissection
owl:Class
Laparoscopic Cholecystectomy
C0162522
Laparoscopic Cholecystectomy
C51681
Cholecystectomy
Surgical removal of the gallbladder,using a laparoscope.
Therapeutic or Preventive Procedure
Therapeutic Laparoscopic Surgery
Laparoscopic Cholecystectomy
Laparoscopic Cholecystectomy
C75387
owl:Class
Human Chorionic Gonadotropin Measurement
C0428402
Human Chorionic Gonadotropin Measurement
Human Chorionic Gonadotropin Measurement
Laboratory Procedure
Human Chorionic Gonadotropin Measurement
Peptide Hormone Measurement
Stereotactic Biopsy
C51654
CL355506
Stereotactic Biopsy
owl:Class
Stereotactic Biopsy
Diagnostic Procedure
Stereotactic Biopsy
An X-ray procedure using multiple coordinates to precisely determine the location of a tumor or nodule so as to obtain a tissue sample.
Biopsy
Medical Inspection
Medical Examination
Medical Assessment
Medical Examination
C0582103
An appraisal or evaluation of a patient's condition by a physician or registered nurse, based on clinical and laboratory data, medical history, and the patient's account of symptoms.
Medical Exam
Examination
Diagnostic Procedure
Medical Examination
C25305
owl:Class
Medical Examination
Diagnostic Procedure
Exam
Protein or Enzyme Type Measurement
Amyloid P Measurement
owl:Class
C81998
Amyloid P Measurement
Amyloid P Measurement
The determination of the amount of amyloid P present in a sample.
Amyloid P Measurement
Publication
Published
C0034037
Publication
Publication
Publication
owl:Class
C48669
The act of issuing printed materials.
Activity
Action
Lymphoma Cell Count
CDISC
CDISC SDTM Terminology
CDISC SEND Terminology
Sezary Cell Count
C74625
Laboratory Procedure
<def-source>CDISC</def-source><def-definition>A measurement of the Sezary cells (atypical lymphocytes with cerebriform nuclei) in a biological specimen.</def-definition>
CL384346
Sezary Cell Count
SEZCE
Clinical Data Interchange Standards Consortium Terminology
Sezary Cells
CDISC SDTM Laboratory Test Terminology by Name
Sezary Cell Count
owl:Class
Sezary Cell Count
CDISC SDTM Laboratory Test Terminology by Code
The determination of the number of Sezary cells present in a sample.
owl:Class
Clinical Pathology Procedure
Laboratory Procedure
Clinical Pathology Procedure
C74944
Laboratory Procedure
A laboratory procedure that involves the examination of blood, urine, other fluids, and stool for diagnostic or research purposes.
Clinical Pathology Procedure
CL384277
Clinical Pathology Procedure
Conditioning
C41258
Physiologic Function
Conditioned
Action
C0009647
owl:Class
Conditioning
Conditioning
Conditioning
Functional Concept
Generally refers to relative simple learning situations in which a stimulus initially incapable of evoking a certain response acquires the ability to do so by repeated pairing with another stimulus that does elicit the response.
Nitrite Measurement
CDISC
A quantitative measurement of the amount of nitrite present in a sample.
Nitrite Measurement
C64810
Laboratory Procedure
NITRITE
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Laboratory Test Terminology by Code
Nitrite Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the nitrite in a urine specimen.</def-definition>
CL385497
Chemistry Test
CDISC SEND Terminology
Nitrite Measurement
CDISC SDTM Terminology
Nitrite
owl:Class
Clinical Data Interchange Standards Consortium Terminology
Arrest
C61462
Arrest
Activity
Action
Arrest
Arrest
owl:Class
Cause to stop.
Arrested
C0237477
owl:Class
Partial Hepatectomy
partial excision of liver
Therapeutic or Preventive Procedure
C15394
Partial Hepatectomy
C0193398
Partial Hepatectomy
subtotal hepatectomy
Partial Hepatectomy
Excision
Hepatectomy
Procedure_Has_Partially_Excised_Anatomy only Liver
Partial removal of the liver
Laser Lithotripsy
Lithotripsy
Laser Therapy
Laser Lithotripsy
CL353503
C51986
Therapeutic or Preventive Procedure
Laser Lithotripsy
owl:Class
Laser Lithotripsy
Clinical Data Interchange Standards Consortium Terminology
Adiponectin Measurement
CL384361
Adiponectin Measurement
CDISC SDTM Laboratory Test Terminology by Code
The determination of the amount of adiponectin hormone present in a sample.
Adiponectin Measurement
Hormone Measurement
CDISC SEND Terminology
Laboratory Procedure
Adiponectin Measurement
C74839
owl:Class
Adiponectin
<def-definition>A measurement of the adiponectin hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Terminology
ADPNCTN
LDH Isoenzyme 3 to LDH Ratio Measurement
CDISC SDTM Terminology
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Code
<def-definition>A relative measurement (ratio or percentage) of the lactate dehydrogenase isoenzyme 3 to total lactate dehydrogenase in a biological specimen.</def-definition><def-source>CDISC</def-source>
LDH Isoenzyme 3/LDH
CDISC SDTM Laboratory Test Terminology by Name
owl:Class
LDH Isoenzyme 3 to LDH Ratio Measurement
LDH3LDH
C79453
Laboratory Procedure
Protein or Enzyme Type Measurement
The determination of the ratio of LDH isoenzyme 3 compared to total LDH present in a sample. The measurement may be expressed as a ratio or percentage.
Clinical Data Interchange Standards Consortium Terminology
LDH Isoenzyme 3 to LDH Ratio Measurement
LDH Isoenzyme 3 to LDH Ratio Measurement
CDISC SDTM Laboratory Test Terminology by Name
C0014772
<def-definition>A measurement of the total erythrocytes per unit of a biological specimen.</def-definition><def-source>CDISC</def-source>
RBC
Laboratory Procedure
Red Blood Cell Count
The determination of the number of erythrocytes in a blood sample.
CDISC
Erythrocyte Count
Erythrocytes
Erythrocyte Count
CDISC SEND Terminology
C51946
owl:Class
Erythrocyte Count
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
Red Cell Count
Red Blood Cells
CDISC SDTM Terminology
Blood Cell Count
Erythrocyte Count
Wedge Biopsy
Wedge Biopsy
Biopsy
Wedge Biopsy
owl:Class
CL355602
Removal of a wedge-shaped portion of tissue, for microscopic examinaton.
Diagnostic Procedure
Wedge Biopsy
C51916
CL354554
Surgery involving partial or complete excision of the tongue.
Glossectomy
Procedure_Has_Excised_Anatomy only Tongue
Therapeutic or Preventive Procedure
Head and Neck Surgery
owl:Class
C51604
Excision of Tongue
Resection of Tongue
Glossectomy
Glossectomy
Glossectomy
owl:Class
A statistical technique used to determine which variables discriminate between two or more naturally groups and to determine whether groups differ with regard to the mean of a variable.
Discriminant Function
Discriminant Function Analysis
Discriminant Function Analysis
C0012630
Research Activity
Statistical Technique
C68834
Discriminant Function Analysis
Discriminant Function Analysis
A radiographic technique used to evaluate a specific anatomic location for a specific purpose.
Image Study
Diagnostic Procedure
Image Study
owl:Class
Image Study
Image Study
CL366218
Diagnostic Imaging
Imaging Study
C63859
Diagnostic Procedure
C0376335
The principle of functional MRI imaging is to take a series of images of an organ in quick succession and to statistically analyze the images for differences among them. Most commonly used in studies of brain function.
functional magnetic resonance imaging
Functional Imaging
Functional Magnetic Resonance Imaging
C17958
Functional Magnetic Resonance Imaging
owl:Class
<def-source>NCI-GLOSS</def-source><def-definition>A noninvasive tool used to observe functioning in the brain or other organs by detecting changes in chemical composition, blood flow, or both.</def-definition>
Functional Magnetic Resonance Imaging
Magnetic Resonance Imaging
Functional MRI
fMRI
Functional Magnetic Resonance Imaging
owl:Class
CDISC SDTM Terminology
Clinical Data Interchange Standards Consortium Terminology
Epinephrine
Adrenaline
CDISC SDTM Laboratory Test Terminology by Code
The determination of the amount of epinephrine present in a sample.
Epinephrine Measurement
CDISC SEND Terminology
EPIN
<def-definition>A measurement of the epinephrine hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
Epinephrine Measurement
C79445
Epinephrine Measurement
Hormone Measurement
Epinephrine Measurement
Laboratory Procedure
Adrenaline Measurement
CDISC SDTM Laboratory Test Terminology by Name
C1608241
Ganglionectomy
C51931
owl:Class
Ganglionectomy
Excision
Ganglionectomy
Ganglionectomy
Therapeutic or Preventive Procedure
Vaccine Development
Vaccine Development
C15660
C0597634
Vaccine Research
Vaccine Development
Suspensions of killed or attenuated microorganisms (bacteria, viruses, or rickettsiae), or of antigenic proteins derived from them, administered for the prevention, amelioration, or treatment of infectious diseases or cancer. Any aspect of vaccine research, development, testing, etc., for diseases other than AIDS. A vaccine must involve the administration of an antigen to induce an active and specific immune response. Induction of passive immunity does not constitute a vaccine although the term is sometimes misused for this process.
Vaccine Development
Health Care Activity
owl:Class
CL322428
Peritoneoscopy
Peritoneoscopy
Peritoneoscopy
C38079
Endoscopic Procedure
Procedure_Has_Target_Anatomy only Peritoneum
Endoscopic examination of peritoneum.
owl:Class
Diagnostic Procedure
Peritoneoscopy
<def-source>CDISC</def-source><def-definition>A measurement of the low density lipoprotein cholesterol in a biological specimen.</def-definition>
CDISC SDTM Terminology
CDISC
CDISC SDTM Laboratory Test Terminology by Code
owl:Class
Serum LDL Cholesterol
Laboratory Procedure
Serum LDL Cholesterol Measurement
Clinical Data Interchange Standards Consortium Terminology
Serum LDL Cholesterol Measurement
Serum LDL Cholesterol Measurement
LDL Cholesterol
CDISC SEND Terminology
A quantitative measurement of the amount of LDL cholesterol present in a sample of serum.
C61042
Serum LDL Cholesterol Measurement
CDISC SDTM Laboratory Test Terminology by Name
Lipid Measurement
LDL
C0428474
Serum Chemistry Measurement
CL014976
C20055
Nucleic Acid Amplification Test
Nucleic Acid Amplification Test
NAT
owl:Class
Nucleic Acid Amplification Test
Laboratory Procedure
Nucleic Acid Testing
Nucleic Acid Amplification Test
Molecular Analysis
Any of various amplification and detection strategies applied to detection of virus contamination in donor blood. Specifically designed to detect recently infected individuals during the latency period before seroconversion.
owl:Class
Diagnostic Procedure
Venography
Venography
Angiography
C38099
C0031545
Venography
A type of X-ray in which contrast medium is injected into a vein to show the details of its structure and any associated abnormalities.
Venography
C0036836
Serum Total Protein Measurement
Laboratory Procedure
Serum Total Protein Measurement
Serum Total Protein Measurement
Serum Chemistry Measurement
C61033
owl:Class
Serum Total Protein Measurement
A quantitative measurement of the total amount of protein present in a sample of serum.
Therapeutic or Preventive Procedure
owl:Class
C15972
Biological Immunotherapy
Biological Immunotherapy
The use of biological agents to enhance the host immune system.
CL003748
Biological Immunotherapy
Biological Immunotherapy
Immunotherapy-Biological
Immunotherapy
Culturing, in vitro Vertebrate, Tissue
CL004381
Culturing, in vitro Vertebrate, Tissue
Tissue Culture
C19480
Culturing, in vitro Vertebrate, Tissue
Laboratory Procedure
Culturing, in vitro Vertebrate, Tissue
owl:Class
Maintenance of vertebrate tissue after removal from the body, by placing in a vessel with a sterile nutritive medium.
Variance Criterion
Variance Criterion
Variance Criterion
Variance Criterion
Method for removing extreme values from a set, based upon its variance. Defined in documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html
Activity
CL369362
Remove Extremes
C64229
owl:Class
CL001096
Experimental or epidemiological studies of viruses as carcinogens or co-carcinogens.
C15876
owl:Class
Virus Cancer Research
Virus Cancer Research
Cancer Research
Research Activity
Virus Cancer Research
Virus Cancer Research
C0040399
owl:Class
SPECT imaging
A type of tomography in which gamma photon-emitting radionuclides are administered to the patient and then detected by one or more gamma cameras rotated around the patient. From the series of two-dimensional images produced, a three-dimensional image can be created by computer reconstruction.
tomography, emission computed, single photon
C17203
Single Photon Emission Computed Tomography
Single Photon Emission Computed Tomography
Tomography, Emission-Computed, Single-Photon
Computed Tomography
Diagnostic Procedure
Single Photon Emission Computed Tomography
Medical Imaging, Single Photon Emission Computed Tomography
Single Photon Emission Computed Tomography
<def-source>MSH2001</def-source><def-definition>A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image.</def-definition>
SPECT
Hypercalcemia Therapy
Therapeutic or Preventive Procedure
C15487
Hypercalcemia Therapy
hypercalcemia control/bone resorption
bone resorption/hypercalcemia control
Supportive Care
CL029488
Hypercalcemia Therapy
owl:Class
Hypercalcemia Therapy
Hierarchical Clustering
C63919
Cluster Analysis
Hierarchical Cluster Analysis
Cluster analysis that uses stepwise partitioning of objects.
Hierarchical Clustering
Hierarchical Clustering
Research Activity
CL366209
Hierarchical Clustering
owl:Class
CL353514
Surgery to remove the left ovary.
Left Oophorectomy
Left Oophorectomy
Left Oophorectomy
Unilateral Oophorectomy
Therapeutic or Preventive Procedure
owl:Class
C51601
Left Oophorectomy
Procedure_Has_Excised_Anatomy only 'Left Ovary'
C0030279
Pancreas Excision
<def-source>NCI-GLOSS</def-source><def-definition>(pan-kree-a-TEK-toe-mee) Surgery to remove all or part of the pancreas. In a total pancreatectomy, part of the stomach, part of the small intestine, the common bile duct, gallbladder, spleen, and nearby lymph nodes also are removed.</def-definition>
Abdominal Surgical Procedure
Digestive System Surgery
Pancreatectomy
C15294
Excision of the Pancreas
Pancreatectomy
pancreatectomy
Therapeutic or Preventive Procedure
Surgical removal of part or all of the pancreas.
Procedure_Has_Excised_Anatomy only Pancreas
owl:Class
Pancreatectomy
Pancreatectomy
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Laboratory Test Terminology by Code
Alpha-fetoprotein Measurement
Clinical Data Interchange Standards Consortium Terminology
Alpha-fetoprotein Measurement
Alpha-fetoprotein Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the alpha fetoprotein in a biological specimen.</def-definition>
The determination of the amount of alpha-fetoprotein present in a sample.
CDISC SEND Terminology
Protein or Enzyme Type Measurement
AFP
owl:Class
Alpha Fetoprotein
CDISC
C74732
C0201539
Alpha-fetoprotein Measurement
Laboratory Procedure
X-Ray Crystallography
C17672
X-Ray Crystallography
owl:Class
A technique in crystallography in which the pattern produced by the diffraction of x-rays through the closely spaced lattice of atoms in a crystal is recorded and then analyzed to reveal the nature of that lattice.
Single Crystal Diffraction
Crystallography
C0206755
Laboratory Procedure
X-Ray Crystallography
X-Ray Crystallography
Crystallography, X-Ray Diffraction
Crystallography, X-Ray/Neutron
CL000046
owl:Class
Clinical trials related to the development of vaccines and therapeutics directed against opportunistic infections associated with HIV infection. These trials include the following opportunistic infections: pneumocystosis, toxoplasmosis, cryptosporidiosis, candidacies, cryptococcosis, mycobacteriosis, cytomegalovirus, papillomavirus, herpes simplex, JC virus, coccidioides, hairy leukoplakia, and HIV-related periodontal disease.
AIDS Clinical Trial
C15766
AIDS, Clinical Trials on Patients with Opportunistic Infections
AIDS, Clinical Trials on Patients with Opportunistic Infections
Research Activity
AIDS, Clinical Trials on Patients with Opportunistic Infections
AIDS, Clinical Trials on Patients with Opportunistic Infections
Equal Probability Sampling Method
CL378109
Equal Probability Sampling Method
owl:Class
Equal Probability Sampling Method
Equal Probability Sampling Method
Quantitative Concept
C71517
Sampling Method
Deafferentation
Therapeutic or Preventive Procedure
Cutting off the afferent nerve supply. Often performed to relieve pain. (Taber's).
owl:Class
Deafferentation
Neurosurgical Procedure
Deafferentation
Denervation
C0011307
Deafferentation
C21002
Nanoparticle Physical Characterization
Nanoparticle Physical Characterization
Nanoparticle Physical Characterization
CL364929
Nanoparticle Physical Characterization
Physical Chemical Technique
The measurement and description of information pertaining to the determination of the physical properties of nanoparticles. These analyses enable the quantification of thermal, electrical and mechanical parameters of these entities.
C62362
Activity
owl:Class
Pacemaker Placement
Pacemaker Placement
Pacemaker Placement
Cardiac Therapeutic Procedure
owl:Class
Therapeutic or Preventive Procedure
C80434
Pacemaker Placement
A surgical procedure in which a small, battery-powered device is placed in the chest wall to transmit electrical impulses to the heart muscles to stimulate contraction.
C64542
Targeting
CL385045
The process of directing an agent to a specific anatomic location.
owl:Class
Activity
Action
Targeting
Targeted
Targeting
Targeting
Population Research
CL001114
owl:Class
C15878
Population Research
Research on fertility, contraceptives, transplacental carcinogenesis or other in utero or pre-conception disease induction.
Research Activity
Population Research
Population Study
Population Research
Diuretic Measurement
Diuretic Measurement
owl:Class
Laboratory Procedure
Drug Class Measurement
C75384
The determination of the amount of any diuretic present in a sample.
CL384483
Diuretic Measurement
Diuretic Measurement
Microbial Sensitivity Test
Microbiology Test
Microbial Sensitivity Test
Microbial Sensitivity Test
Microbial Sensitivity Test
Laboratory Procedure
owl:Class
CL353533
C51954
Molecular Genetic Technique
<def-source>NCI-GLOSS</def-source><def-definition>A laboratory method used to make many copies of a specific DNA sequence.</def-definition>
Polymerase Chain Reaction
Polymerase Chain Reaction
PCR
polymerase chain reaction
A method for amplifying a DNA base sequence using multiple rounds of heat denaturation of the DNA and annealing of oligonucleotide primers complementary to flanking regions in the presence of a heat-stable polymerase. This results in duplication of the targeted DNA region. Newly synthesized DNA strands can subsequently serve as additional templates for the same primer sequences, so that successive rounds of primer annealing, strand elongation, and dissociation produce rapid and highly specific amplification of the desired sequence. PCR also can be used to detect the existence of the defined sequence in a DNA sample.
owl:Class
Polymerase Chain Reaction
Molecular Analysis
C17003
C0032520
Polymerase Chain Reaction
Molecular Biology Research Technique
Laboratory Procedure
C16226
Research into the combination of knowledge, practices, and attitudes that motivate the actions we take regarding health.
CL027069
Health and Behavior
Research Activity
Behavioral Research
Health and Behavior
Health and Behavior
Health and Behavior
owl:Class
<def-source>NCI-GLOSS</def-source><def-definition>(ful-gyoor-AY-shun) Destroying tissue using an electric current.</def-definition>
Fulguration
Fulguration
C0013804
Fulguration
Therapeutic or Preventive Procedure
Surgical Procedure by Method
owl:Class
fulguration
Fulguration
C15390
owl:Class
estrogen replacement therapy
C15231
Postmenopausal Hormone Replacement Therapy
Estrogen Replacement Therapy
<def-source>NCI-GLOSS</def-source><def-definition>Hormones (estrogen, progesterone, or both) given to postmenopausal women or to women who have had their ovaries surgically removed. Hormones are given to replace the estrogen no longer produced by the ovaries.</def-definition>
Estrogen Replacement
Estrogen Replacement Therapy
Estrogen Therapy
Therapeutic or Preventive Procedure
C0014935
ERT
The administration of estrogen, especially in postmenopausal women, to relieve menopausal symptoms and to protect against osteoporosis and heart disease. (Bartleby.com)
<def-source>MSH2001</def-source><def-definition>The use of hormonal agents with estrogen-like activity in postmenopausal or other estrogen-deficient women to alleviate effects of hormone deficiency, such as vasomotor symptoms, dyspareunia, and progressive development of osteoporosis. This may also include the use of progestational agents in combination therapy.</def-definition>
Estrogen Replacement Therapy
Estrogen Replacement Therapy
Survival
Quantitative Concept
Relative Survival
Relative Survival
Relative Survival
owl:Class
C53370
Relative Survival
CL356720
Molecular Profiling
Molecular Analysis
owl:Class
Molecular Profiling
Expression Signature
Laboratory Procedure
Molecular Profiling
Molecular Profiling
Expression Profiling
CL008760
C19771
Molecular Fingerprinting
Molecular profiling studies utilize measurement of global mRNA and protein patterns towards identification of the individual genes and collections of genes that mediate particular aspects of cellular physiology and pathology.
CDISC SDTM Laboratory Test Terminology by Code
C74858
Gastrin Measurement
GASTRIN
CDISC SEND Terminology
owl:Class
CDISC SDTM Terminology
Hormone Measurement
Laboratory Procedure
Gastrin
Gastrin Measurement
Gastrin Measurement
The determination of the amount of gastrin hormone present in a sample.
Gastrin Measurement
<def-definition>A measurement of the gastrin hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Laboratory Test Terminology by Name
C0202036
Clinical Data Interchange Standards Consortium Terminology
F-Test
F Test
Quantitative Concept
F-Test
CL355879
F-Test
A test of the hypothesis that the standard deviations of two normally distributed populations are equal, and thus that they are of comparable origin.
C53234
owl:Class
Parametric Test
F-Test
Laboratory Procedure
owl:Class
Complement C1q Antibody Measurement
The determination of the amount of complement C1q antibody present in a sample.
Complement C1q Antibody Measurement
Complement C1q Antibody Measurement
Complement C1q Antibody Measurement
C80173
Complement Measurement
barium swallow
Esophagography
Esophagography
Barium Swallow
Procedure_Has_Imaged_Anatomy only Esophagus
Radiography
Diagnostic Procedure
Esophagography
The process of obtaining contrast esophagrams.
Esophagography
Contrast Esophagraphy
owl:Class
C38112
C0203065
Laboratory Procedure
Mutagenicity Test
Mutagenicity Test
owl:Class
C16214
CL026257
Diagnostic Procedure
Carcinogen Screening
Research Activity
Mutagenicity Test
Mutagenicity Test
Abdominal X-Ray
C38102
Abdominal Radiography
Abdominal Radiography
C0034573
Abdominal Radiography
Diagnostic Procedure
Abdominal Radiography
owl:Class
A radiographic procedure to form an image of the abdomen.
Radiography
A non-invasive cardiac ultrasound performed by placing the transducer on the chest.
Echocardiography
owl:Class
Transthoracic Echocardiography
Transthoracic Echocardiography
Transthoracic Echocardiography
C80404
Diagnostic Procedure
Transthoracic Echocardiography
Magnetic Resonance Elastography
C19338
Magnetic Resonance Elastography
This imaging technique returns information about the mechanical properties (feel) of tissues by combining MRI with ultrasound. A properly equipped MRI machine captures a cross sectional image of the sound waves, produced by ultrasound techniques, which are then processed by computer to produce an image showing the hardness or elasticity of tissues within the cross section.
Magnetic Resonance Spectroscopic Imaging
owl:Class
CL003817
Magnetic Resonance Elastography
Diagnostic Procedure
Magnetic Resonance Elastography
Gonzalez Regimen
Therapeutic or Preventive Procedure
Gonzalez Regimen
CL343563
Gonzalez Regimen
Gonzalez Regimen
CAM Multimodality Therapy
C62678
owl:Class
Bioconductor caAffy Quantiles Normalization
C63935
CL369468
Bioconductor caAffy Quantiles Normalization
owl:Class
Bioconductor caAffy Quantiles Normalization
A method for normalization based upon quantiles. This function normalizes a matrix of probe level intensities. Defined in documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html
Statistical Technique
Activity
Bioconductor caAffy Quantiles Normalization
Internal Radiation Brachytherapy
CL370849
C66889
Internal Radiation Brachytherapy
Radiation Brachytherapy
Internal Radiation Brachytherapy
Therapeutic or Preventive Procedure
Internal Radiation Therapy
Internal Radiation Brachytherapy
owl:Class
Lymph Node Mapping
Lymph Node Mapping
CL031832
Lymph Node Mapping
Diagnostic Procedure
<def-source>NCI-GLOSS</def-source><def-definition>The use of dyes and radioactive substances to identify lymph nodes that contain tumor cells.</def-definition>
Lymph Node mapping, also known as sentinel lymph node (SLN) mapping is a procedure in which a radioactive tracer and a blue dye is injected around the tumor site. These two substances travel from the tumor and drain into the sentinel, or main, lymph node. Together they provide a marker for the location and presence of a sentinel lymph node, allowing discovery of minute metastases areas.
owl:Class
Diagnostic Procedure
lymph node mapping
Lymph Node Mapping
C18210
Lactation / Infant Nutrition
Infant Nutrition
Nutritional Study
C15264
Infant Nutrition
Nutritional studies with a focus on the specific nutritional needs of children under the age of 2.
<def-source>MSH2001</def-source><def-definition>Nutrition of children from birth to 2 years of age.</def-definition>
owl:Class
Dietary Intervention
Infant Nutrition
Organism Function
C0021279
Infant Nutrition
Elutriative Centrifugation
Fractionation, Centrifugation, Elutriation
Elutriative Centrifugation
Elutriative Centrifugation
Elutriative Centrifugation
C18798
Centrifugation
owl:Class
CL000401
Laboratory Procedure
Separation of particles on the basis of their differential sedimentation rate.
Pelger Huet Anomaly Measurement
CDISC
The determination of the amount of Pelger Huet anomaly present in a sample.
owl:Class
Pelger Huet Anomaly Measurement
Pelger Huet Anomaly Measurement
Pelger Huet Anomaly Measurement
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Terminology
Laboratory Procedure
PELGERH
CDISC SDTM Laboratory Test Terminology by Name
Clinical Data Interchange Standards Consortium Terminology
CL384761
<def-definition>A measurement of the Pelger Huet Anomaly (nuclei of neutrophils and eosinophils appear rod-like, spherical or dumbbell shaped) in a biological specimen.</def-definition><def-source>CDISC</def-source>
C74617
Hematology Test
Pelger Huet Anomaly
owl:Class
Case Report
Case Study
Case Study
Study Design
An uncontrolled observational study containing a detailed report of the diagnosis, treatment, and follow-up of an individual patient. Case reports also contain some demographic information about the patient (for example, age, gender, ethnic origin).
Case Study
Research Activity
C0085973
Case Study
case report
C15362
<def-source>NCI-GLOSS</def-source><def-definition>A detailed report of the diagnosis, treatment, and follow-up of an individual patient. Case reports also contain some demographic information about the patient (for example, age, gender, ethnic origin).</def-definition>
Diagnostic Procedure
Venacavography
owl:Class
Venacavography
Venacavography
Venacavography
A type of X-ray in which contrast medium is injected into a vein to show the details of the structure of the vena cava and any associated abnormalities.
C38098
CL322440
Angiography
paracentesis
C15310
Paracentesis
<def-source>NCI-GLOSS</def-source><def-definition>Insertion of a thin needle or tube into the abdomen to remove fluid from the peritoneal cavity.</def-definition>
C0034115
Aspiration
Paracentesis
Paracentesis
owl:Class
Paracentesis
Diagnostic Procedure
<def-source>MSH2001</def-source><def-definition>A procedure in which fluid is withdrawn from a body cavity via a trocar and cannula, needle, or other hollow instrument.</def-definition>
Therapeutic or Preventive Procedure
Aspiration of Breast
Procedure using a thin needle and syringe to remove bodily fluid or tissue from the breast.
C51634
Aspiration of Breast
Diagnostic Procedure
Aspiration of Breast
C0191846
owl:Class
Aspiration of Breast
Aspiration
Procedure_Has_Completely_Excised_Anatomy some 'Small Intestine'
C51515
Total Small Bowel Resection
Total Small Intestine Resection
Total Small Intestine Resection
Total Small Intestine Resection
Small Intestine Resection
Therapeutic or Preventive Procedure
CL354836
Total Small Intestine Resection
Complete Small Intestine Resection
Surgical removal of the entire small intestine.
owl:Class
Breast Cancer Prevention, Education, and Diagnosis Program Initiative
Breast Cancer Prevention, Education, and Diagnosis Program Initiative
Breast Cancer Prevention
Health Care Activity
owl:Class
Breast Cancer Prevention, Education, and Diagnosis Program Initiative
Breast Cancer Prevention, Education, and Diagnosis Program Initiative
CL004503
C16020
Diagnostic Procedure
owl:Class
C81177
Infant Screening
Infant Screening
Infant Screening
Infant Assessment
Age Appropriate Screening
Infant Screening
Diagnostic tests performed on infants to assess overall health and identify potential areas of concern.
C21063
Low Emission Laser Therapy
Low-Emission Laser Therapy
CL100616
Use of low-emission laser therapy has been shown to reduce pain when applied directly to the painful area or to acupuncture points. The mechanism is unknown. It has also been shown to postpone post-traumatic neural degeneration. (from Kanner)
Low Level Laser Therapy
Cold Laser Therapy
Therapeutic or Preventive Procedure
Low Emission Laser Therapy
Pain Therapy
Low Emission Laser Therapy
owl:Class
Low Emission Laser Therapy
Faith Healing
C51973
Mental Process
Spiritual Therapy
Faith Healing
owl:Class
Faith Healing
CL353392
Faith Healing
Therapeutic or Preventive Procedure
Fertility Preservation
Fertility Preservation
Fertility Preservation
owl:Class
C1171194
C71326
Fertility Preservation
Therapeutic Procedure
Methods that focus on the retention of a woman's reproductive capability.
C0079603
C17370
Immunologic, Immunofluorescence
owl:Class
Fluorescent Antibody Procedure
Immunofluorescence
Fluorescent Antibody Procedure
Fluorescent Antibody Procedure
Immunology Test
An immunological procedure in which the antibodies are coupled with molecules which fluoresce under ultra violet (UV) light. This makes them particularly suitable for detection of specific antigens in tissues or on cells.
Laboratory Procedure
Fluorescent Antibody Procedure
Role of Vitamin A, its precursons, and its analogs in cancer causation or prevention and in general health.
Nutrition, Vitamin A
Nutrition, Vitamin A
Nutrition, Vitamins
owl:Class
CL102252
Nutrition, Vitamin A
Nutrition, Vitamin A
C16015
Research Activity
Unconventional Physical Therapy
Unconventional Physical Therapy
Therapeutic or Preventive Procedure
Unconventional Physical Therapy
Manipulative and Body-Based Intervention Procedure
C15909
CL002442
owl:Class
Unconventional Physical Therapy
Immunology Test
Cancer Antigen 125 Measurement
Cancer Antigen 125 Measurement
owl:Class
The determination of the amount of cancer antigen 125 present in a sample.
C81981
Cancer Antigen 125 Measurement
Cancer Antigen 125 Measurement
Ambulatory Surgical Procedure
C0002428
Ambulatory Surgical Procedure
Ambulatory Surgical Procedure
owl:Class
Surgical Procedure
Therapeutic or Preventive Procedure
Ambulatory Surgical Procedure
A surgical procedure performed on an outpatient basis. It may be hospital-based or performed in an office or surgicenter.
C51997
Stem Cell Factor Measurement
C82035
Stem Cell Factor Measurement
Stem Cell Factor Measurement
Protein or Enzyme Type Measurement
Stem Cell Factor Measurement
The determination of the amount of stem cell factor present in a sample.
owl:Class
Desensitization, Immunologic
Immunologic Desensitization
<def-source>MSH2001</def-source><def-definition>Immunosuppression by the administration of increasing doses of antigen. Though the exact mechanism is not clear, the therapy results in an increase in serum levels of allergen-specific IgG, suppression of specific IgE, and an increase in suppressor T-cell activity.</def-definition>
Immunologic Desensitization
Immunologic Desensitization
C15377
owl:Class
Immunologic Desensitization
Therapeutic or Preventive Procedure
C0162352
Treatment or therapy to reduce or eliminate a patient's allergic response to an allergen (NCI/OSP)
Desensitization
Hyposensitization Therapy
Immunotherapy
Birth Method of Delivery
C81303
Vaginal Delivery
Vaginal Delivery
owl:Class
The method referring to the delivery of a fetus through the vaginal canal.
Vaginal Delivery
Vaginal Delivery
Newborn Screening
Therapeutic or Preventive Procedure
<def-source>CDISC</def-source><def-definition>A measurement of the leukemic blasts (lymphoblasts that remain in an immature state even when outside the bone marrow) in a biological specimen.</def-definition>
BLASTLM
Lymphoblasts
Leukemic Blast Count
CDISC SDTM Laboratory Test Terminology by Code
C74630
Clinical Data Interchange Standards Consortium Terminology
Leukemic Blast Count
Leukemic Blasts
Leukemic Blast Count
CDISC SEND Terminology
owl:Class
Leukemic Blast Count
CL384700
Blast Count
Lymphocytes
Laboratory Procedure
CDISC
CDISC SDTM Laboratory Test Terminology by Name
Immunoblastic
CDISC SDTM Terminology
The determination of the number of leukemic blasts present in a sample.
CL053953
Research Activity
Pediatric Research
Pediatric Research
Human Subject Research
Pediatric Research
Pediatric Research
C26026
owl:Class
Crystal Growth Measurement
CDISC SDTM Terminology
CDISC SEND Terminology
Clinical Data Interchange Standards Consortium Terminology
CL384751
CDISC SDTM Laboratory Test Terminology by Name
The determination of the amount of monosodium urate crystals present in a sample.
CDISC
Monosodium Urate Crystal Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the monosodium urate crystals present in a biological specimen.</def-definition>
owl:Class
Monosodium Urate Crystal Measurement
C74681
CDISC SDTM Laboratory Test Terminology by Code
Laboratory Procedure
CYMSU
Monosodium Urate Crystals
Monosodium Urate Crystal Measurement
Monosodium Urate Crystal Measurement
Micronutrients
Nutrition, Trace Elements
C15605
Trace Element Nutrition
Research Activity
owl:Class
Nutrition, Trace Elements
Nutrition, Dietary Components
CL372155
Trace Nutrients
Nutrition, Trace Elements
Role of trace elements in cancer causation or prevention and in general health.
Nutrition, Trace Elements
C0002692
Procedure_Has_Partially_Excised_Anatomy only 'Lower Extremity'
Below-Knee Amputation
Amputation of Leg Through Tibia and Fibula
Procedure_Has_Partially_Excised_Anatomy only Leg
Procedure_Has_Completely_Excised_Anatomy only Foot
Therapeutic or Preventive Procedure
Amputation of Leg Through Tibia and Fibula
Amputation of Leg Through Tibia and Fibula
Amputation of Leg Through Tibia and Fibula
C51702
The surgical removal of part or all of leg that is below the knee.
owl:Class
Amputation
Procedure_Has_Partially_Excised_Anatomy only Tibia
Procedure_Has_Partially_Excised_Anatomy only Fibula
Orthopedic Surgical Procedure
urinalysis
Urinalysis
Laboratory analysis of urine, commonly used to aid in the diagnosis of disease or to detect the presence of a specific substance. It involves examination of the urine by physical or chemical means as well as microscopic examination that helps to screen for urinary tract infections, renal disease, and diseases of other organs, that result in abnormal metabolites (break-down products) appearing in the urine.
C17241
<def-source>NCI-GLOSS</def-source><def-definition>A test that determines the content of the urine.</def-definition>
Urinalysis
owl:Class
Urinalysis
C0042014
Laboratory Procedure
Urinalysis
Chemistry Test
Mental Process
Biofield Therapy
Distance Healing
owl:Class
C51974
Distance Healing
CL355051
Distance Healing
Distance Healing
owl:Class
Diagnostic or Prognostic Test
A test perfomed to identify a disease or make a prediction of the course of the disease.
CL102823
Diagnostic Procedure
Diagnostic or Prognostic Test
Health Care Activity
Diagnostic or Prognostic Test
Diagnostic or Prognostic Test
C18742
Therapeutic or Preventive Procedure
CL370850
Interstitial Radiation Therapy
Interstitial Radiation Therapy
Internal Radiation Therapy
C66891
owl:Class
Interstitial Radiation Therapy
Interstitial Radiation Therapy
Second Line Treatment
Second Line Treatment
FDA
Treatment Regimen
CL357204
owl:Class
Limitation Of Use Structured Product Labeling Terminology
Therapeutic or Preventive Procedure
Second Line Treatment
Second Line Treatment
C54350
Structured Product Labeling Terminology
Second Line Therapy
Confidence Interval
C53324
Confidence Interval
Confidence Interval
Confidence Interval
owl:Class
C0009667
A range of values for a parameter that may contain the parameter and the degree of confidence that it is in fact there.
Quantitative Concept
Dispersion
Surgical reconstruction of the breast.
C51614
owl:Class
Procedure_Has_Target_Anatomy only 'Mammary Gland'
Mammoplasty
CL355267
Mammoplasty
Procedure_Has_Target_Anatomy only Breast
Therapeutic or Preventive Procedure
Mammoplasty
Mammoplasty
Surgical Procedure by Site or System
C72662
Cosine Distance Method
Quantitative Concept
A type of pearson measure, which considers the relative differences (e.g. A*B/|A|.|B|) assuming that the scale is uniform (that the distance from zero is relative). In some cases this can give better results, particularly where the data is not 'normally' distributed.
Cosine Distance Method
Cosine Distance Method
CL369818
owl:Class
Cosine Distance
Statistical Technique
Cosine Distance Method
<def-source>DICOM</def-source><def-definition>Image where signals are identified and separated according to their frequencies, e.g., to identify individual chemicals, or individual nuclei in a chemical compound.</def-definition>
C17155
Spectroscopy
C0037812
Spectroscopy
The technique of measuring the emission and absorption of different wavelengths (spectra) of visible and non-visible light. This can be done via a spectroscope, which consists of a slit, prism, collimator lens, object lens, and a grating.
Diagnostic Imaging
Diagnostic Procedure
Spectroscopy
Physical Chemical Technique
Spectroscopy
owl:Class
Laboratory Procedure
N-Acetyl Glucosamide to Creatinine Ratio Measurement
N-Acetyl Glucosamide to Creatinine Ratio Measurement
CDISC SDTM Laboratory Test Terminology by Name
<def-definition>A relative measurement (ratio or percentage) of the N-acetyl glucosamide to creatinine in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Terminology
N-Acetyl Glucosamide to Creatinine Ratio Measurement
owl:Class
CDISC SDTM Laboratory Test Terminology by Code
N-Acetyl Glucosamide/Creatinine
NAGCREAT
Clinical Data Interchange Standards Consortium Terminology
C79460
CDISC SEND Terminology
Laboratory Procedure
The determination of the ratio of N-acetyl glucosamide compared to creatinine present in a sample. The measurement may be expressed as a ratio or percentage.
N-Acetyl Glucosamide to Creatinine Ratio Measurement
Urine Protein Measurement
Septal Ablation
owl:Class
Therapeutic or Preventive Procedure
C80439
Cardiac Therapeutic Procedure
A cardiac catheterization procedure to relieve symptoms in patients with severe obstructive hypertrophic cardiomyopathy. A catheter is used to localize the septal artery that carries blood to the hypertrophic muscle responsible for the obstruction. A small amount of alcohol is subsequently injected into the catheter to destroy the hypertrophic muscle.
Septal Ablation
Septal Ablation
Septal Ablation
Ablation Therapy
CL374286
The formula to calculate body surface area in cats. It is mathematically defined as: BSA (m^2) = (10.1 x Weight(g)^2/3)/1000
Body Surface Area Formula
Felis domesticus BSA Formula
Occupational Activity
Feline
BSA Formula for Cats
Body Surface Area Formula for Cats
Body Surface Area Formula for Cats
owl:Class
Body Surface Area Formula for Cats
C68653
Body Surface Area Formula for Cats
Quantitative Concept
owl:Class
CL356542
C53203
Sequential Sampling
Sequential Sampling
Sequential Sampling
Nonrandom Sampling
Sequential Sampling
C53214
CL356379
Continuous Distribution
owl:Class
Quantitative Concept
Uniform Distribution
Uniform Distribution
Uniform Distribution
Uniform Distribution
A continuous statistical distribution whose variable of interest has a single probability of occurrence over all possible values.
Procedure_Has_Excised_Anatomy only 'Left Fallopian Tube'
Surgery to remove part or all of both fallopian tubes.
Bilateral Salpingectomy
Bilateral Salpingectomy
Therapeutic or Preventive Procedure
CL354985
Salpingectomy
C51667
Procedure_Has_Excised_Anatomy only 'Right Fallopian Tube'
owl:Class
Bilateral Salpingectomy
Bilateral Salpingectomy
Cell-free System
<def-source>CSP2000</def-source><def-definition>experimental condition created by disrupting cells with homogenization, sonication, detergents, or other treatment, leaving intracellular components exposed to controlled manipulation of the medium.</def-definition>
owl:Class
Cell-free System
C15201
C0007625
Cell-free System
in vitro Assay
Research Device
<def-source>MSH2001</def-source><def-definition>A fractionated cell extract that maintains a biological function. A subcellular fraction isolated by ultracentrifugation or other separation techniques must first be isolated so that a process can be studied free from all of the complex side reactions that occur in a cell. The cell-free system is therefore widely used in cell biology. (From Alberts et al., Molecular Biology of the Cell, 2d ed, p166)</def-definition>
Cell-free System
CDISC SEND Terminology
Mean Platelet Volume Measurement
CDISC SDTM Laboratory Test Terminology by Code
Hematology Test
C0200665
CDISC
Mean Platelet Volume Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the average size of the platelets present in a blood sample.</def-definition>
C74730
MPV
Mean Platelet Volume Measurement
CDISC SDTM Terminology
Mean Platelet Volume
Laboratory Procedure
Clinical Data Interchange Standards Consortium Terminology
The determination of the average size of the platelets present in a blood sample.
owl:Class
CDISC SDTM Laboratory Test Terminology by Name
Mean Platelet Volume Measurement
Quantitative Concept
The minimum time between successive cycles of contraction and subsequent relaxation of the ventricles, usually expressed as beats per minute, obtained from a set of measurements of the ventricular rate.
Clinical Data Interchange Standards Consortium Terminology
Minimum Ventricular Heart Rate
Minimum Ventricular Heart Rate
<def-source>CDISC</def-source><def-definition>The minimum time between successive cycles of contraction and subsequent relaxation of the ventricles, usually expressed as beats per minute, obtained from a set of measurements of the ventricular rate. (NCI)</def-definition>
Ventricular Heart Rate
CDISC SDTM ECG Test Name Terminology
Minimum Ventricular Heart Rate
Minimum Ventricular Heart Rate
Summary (Min) Ventricular Rate
owl:Class
C62153
CDISC SDTM Terminology
CDISC SDTM ECG Test Terminology by Code
CL365071
CDISC
VRMIN
Laboratory Procedure
Trichrome Staining Method
C78218
Sudan IV Staining Method
Sudan IV Staining Method
Sudan IV Staining
Special Histology Staining Method
Sudan IV Staining Method
The use of Sudan IV, a lysochrome (fat soluble dye) diazo dye, for the staining of lipids, triglycerides and lipoproteins on frozen paraffin sections.
Sudan IV Staining Method
C1294075
owl:Class
C51684
Therapeutic or Preventive Procedure
Procedure_Has_Excised_Anatomy only 'Pharyngeal Tonsil'
Tonsillectomy with Adenoidectomy
Tonsillectomy with Adenoidectomy
Tonsillectomy with Adenoidectomy
Procedure_Has_Excised_Anatomy only Tonsil
owl:Class
CL354831
Surgical removal of the tonsils and adenoids.
Tonsillectomy with Adenoidectomy
Head and Neck Surgery
Penultimate Observation Carried Forward Imputation Technique
Quantitative Concept
The substitution of missing data with the next-to-last value that is not missing.
Penultimate Observation Carried Forward Imputation Technique
Penultimate Observation Carried Forward Imputation Technique
C81205
owl:Class
Penultimate Observation Carried Forward Imputation Technique
Statistical Imputation
Serum Alanine Aminotransferase Measurement
Serum Alanine Aminotransferase Measurement
Serum Chemistry Measurement
A quantitative measurement of the amount of alanine aminotransferase present in a sample of serum.
C61017
CL364116
Alanine Aminotransferase Measurement
owl:Class
Laboratory Procedure
Serum Alanine Transaminase Measurement
Serum Alanine Aminotransferase Measurement
Serum Alanine Aminotransferase Measurement
Serum SGPT Measurement
Microbiology Test
Microbiology Test
Microbiology Test
Clinical Pathology Procedure
Microbiology Test
Laboratory Procedure
A laboratory procedure to detect microorganisms in a sample.
C0085672
owl:Class
C49188
Deletion
C61330
Elimination, especially by blotting out, cutting out, or erasing.
owl:Class
Activity
Deletion
Deletion
CL364165
Deletion
Action
Deleted
Class I Restoration
Class I Restoration
Class I Restoration
Class I Restoration
Therapeutic or Preventive Procedure
C52572
Dental Restoration
CL356252
Reconstruction of the occlusal surface of a tooth.
owl:Class
Erythrocyte Distribution Width Measurement
owl:Class
CDISC SDTM Laboratory Test Terminology by Code
Erythrocytes Distribution Width
CDISC
Clinical Data Interchange Standards Consortium Terminology
C0427460
An index of the variation in the size of the red cells and can be used to detect subtle degress of anisocytosis. It is computed directly from the RBC histogram and is calculated as a standard statictical value, the coefficient of variation of the red cell volume ditribution (ratio of standard deviation and mean copuscular volume).
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Name
<def-source>CDISC</def-source><def-definition>A value derived from mean corpuscular volume and the standard deviation of the red blood cell volume in a whole blood specimen.</def-definition>
Erythrocyte Distribution Width Measurement
Hematology Test
Erythrocyte Distribution Width Measurement
CDISC SEND Terminology
Laboratory Procedure
Erythrocyte Distribution Width Measurement
C64800
RDW
Ventricular Heart Rate
C62151
Ventricular Heart Rate
CL364971
Heart Rate
Quantitative Concept
Ventricular Heart Rate
owl:Class
Ventricular Heart Rate
DIGE
C70654
Differential In-Gel Electrophoresis
Differential In-Gel Electrophoresis
Laboratory Procedure
owl:Class
Gel Electrophoresis
CL375786
Differential In-Gel Electrophoresis
Difference Gel Electrophoresis
Molecular Biology Research Technique
A form of gel electrophoresis where up to three different protein samples can be labeled with fluorescent dyes prior to two-dimensional electrophoresis in the same gel. After the gel electrophoresis, the gel is scanned with the excitation wavelength of each dye and the imges are superimposed, allowing detection of changes in protein abundance between samples.
Differential In-Gel Electrophoresis
Alpha Naphthyl Esterase Stain
Alpha Naphthyl Esterase Staining Method
C28441
Laboratory Procedure
Alpha Naphthyl Esterase Staining Method
Alpha Naphthyl Esterase Staining Method
Alpha Naphthyl Esterase Staining Method
owl:Class
A cytochemical staining technique using the alpha-naphthyl esterase staining method or a nonspecific esterase staining method to identify and quantify monoblasts and monocytes and to detect esterase activity. The esterase enzyme contained within monocytes and macrophages reacts strongly with the substrate alpha-naphthyl butyrate. The test is useful in diagnosis of acute leukemias. It marks immature monocytes, and thus is useful in the diagnosis of acute myelogenous leukemia of monocytic type.
Special Histology Staining Method
Alpha Naphthyl Butyrate Esterase Stain
Alpha Naphthyl Esterase Staining Method
CL101881
Aspiration
Diagnostic Aspiration
Diagnostic Aspiration
Diagnostic Aspiration
C0558581
Diagnostic Procedure
Diagnostic Aspiration
C64989
Diagnostic Surgical Procedure
owl:Class
Lactate Dehydrogenase Measurement
Protein or Enzyme Type Measurement
CDISC
C64855
Lactate Dehydrogenase Measurement
CDISC SDTM Laboratory Test Terminology by Code
A quantitative measurement of the amount of lactate dehydrogenase present in a sample.
Clinical Data Interchange Standards Consortium Terminology
Lactate Dehydrogenase Measurement
Lactate Dehydrogenase Measurement
Lactate Dehydrogenase
CDISC SEND Terminology
CDISC SDTM Terminology
<def-source>CDISC</def-source><def-definition>A measurement of the lactate dehydrogenase in a biological specimen.</def-definition>
C0202113
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Name
owl:Class
LDH
Punch Biopsy
owl:Class
Punch Biopsy of Skin
Diagnostic Procedure
C0184924
Punch Biopsy
Punch Biopsy
C28743
Punch Biopsy
Removal of a disk of skin tissue, for microscopic examination, using a punch.
Skin Biopsy
Galactose Measurement
Newborn Screening
Galactose Measurement
The measurement of the amount of galactose in a biologic specimen.
Chemistry Test
C81308
Laboratory Procedure
owl:Class
Galactose Measurement
Galactose Measurement
Biopsy of Thyroid Gland
Biopsy of Thyroid Gland
CL355004
owl:Class
Biopsy
Biopsy of Thyroid Gland
Removal of tissue from the thyroid gland for microscopic examination.
C51613
Biopsy of Thyroid Gland
Diagnostic Procedure
Procedure_Has_Partially_Excised_Anatomy only 'Thyroid Gland'
Peripheral Blood Lymphocyte Therapy
Peripheral Blood Lymphocyte Therapy
C15505
Leukocyte Therapy
peripheral blood lymphocyte therapy
<def-source>NCI-GLOSS</def-source><def-definition>A treatment for Epstein-Barr virus infection or overgrowth of white blood cells (lymphocytes) after an organ or bone marrow transplant. Specific lymphocytes from a sibling donor are infused into the patient to try and reverse these conditions.</def-definition>
Peripheral Blood Lymphocyte Therapy
CL029680
owl:Class
Peripheral Blood Lymphocyte Therapy
Therapeutic or Preventive Procedure
Polyp Prevention Trial
CL014530
Research Activity
Clinical Study by Targeted Disease or Condition
Investigated low fat, high fiber diets in preventing recurrence of colorectal polyps
Polyp Prevention Trial
owl:Class
Polyp Prevention Trial
C16163
Prevention Study
Polyp Prevention Trial
Breast Implant Procedure
Breast Prosthesis Implantation
Surgical implantation of a breast prosthesis.
owl:Class
Breast Prosthesis Implantation
Breast Prosthesis Implantation
C0178391
Breast Prosthesis Implantation
Breast Reconstruction
Therapeutic or Preventive Procedure
C28336
Myringotomy
Myringotomy
CL375742
Myringotomy
Head and Neck Surgery
Myringotomy
Incision of Eardrum
owl:Class
Therapeutic or Preventive Procedure
C70905
Surgical incision into the eardrum.
Therapeutic or Preventive Procedure
Pain Management Method
C26387
A pain management technique based on improvement of functional ability, strengthening, and maintenance of range of motion. It is believed that endorphin release during exercise minimizes pain and improves effectiveness of analgesics.
Exercise Pain Management
Exercise Pain Management
Exercise Pain Management
C1522704
Exercise
Exercise Pain Management
owl:Class
owl:Class
Administrative Activity
Dental Recall
C52573
Dental Recall
CL356256
A routine dental appointment for a patient of record that includes diagnostic procedures and preventive care.
Activity
Dental Recall
Dental Recall
Research that focuses on food, the nutrients and other substances contained therein, their action, interaction, and balance in relation to health and disease.
Nutritional Study
owl:Class
Nutritional Study
CL000599
C15820
Study
Nutritional Study
Research Activity
Nutritional Study
Nutrition
Nutrition Research
owl:Class
Health Behavior
Health Behavior
C16663
Personal Behavior
Health and Behavior
<def-source>CSP2000</def-source><def-definition>human attitudes and behaviors related to health; e.g., diet, exercise, care-seeking, substance avoidance, therapy compliance, etc.</def-definition>
Health Behavior
C0018687
<def-source>MSH2001</def-source><def-definition>Behaviors expressed by individuals to protect, maintain or promote their health status. For example, proper diet, and appropriate exercise are activities perceived to influence health status. Life style is closely associated with health behavior and factors influencing life style are socioeconomic, educational, and cultural.</def-definition>
Health Behavior
Individual Behavior
Alcohol Consumption
Consumption of liquids containing ethanol, including the behaviors associated with drinking the alcohol.
Alcohol Consumption
Individual Behavior
Personal Behavior
C0001948
Alcohol Consumption
owl:Class
C16273
Alcohol Consumption
Heart Rate
CDISC SDTM Terminology
C62096
HRMIN
Quantitative Concept
Minimum Heart Rate
Minimum Heart Rate
CDISC SDTM ECG Test Terminology by Code
<def-source>CDISC</def-source><def-definition>The maximum time between successive cycles of contraction and subsequent relaxation of the heart, usually expressed as beats per minute, obtained from a set of measurements of the heart rate. (NCI)</def-definition>
The maximum time between successive cycles of contraction and subsequent relaxation of the heart, usually expressed as beats per minute, obtained from a set of measurements of the heart rate.
Summary (Min) Heart Rate
owl:Class
CL364576
CDISC SDTM ECG Test Name Terminology
Clinical Data Interchange Standards Consortium Terminology
CDISC
Minimum Heart Rate
Minimum Heart Rate
C41604
Specimen Processing
Specimen Processing
owl:Class
Specimen Processing
The process of preparing a sample or portion of a sample for storage, preservation, or further analysis.
Activity
C0037793
Specimen Processing
Action
C18883
Protein Sequencing
CL000556
Protein Sequencing
Molecular Biology, Protein Sequencing
The process of determining the sequence of amino acids within a protein molecule.
Protein Sequencing
owl:Class
Laboratory Procedure
Protein Analysis
Protein Sequencing
The formula to calculate body surface area as described by EA Gehan and SL George. It is mathematically defined as: BSA (m^2) = 0.0235 x Height(cm)^0.42246 x Weight(kg)^0.51456
Body Surface Area Formula
owl:Class
Gehan and George Body Surface Area Formula
C68649
Occupational Activity
Gehan and George Body Surface Area Formula
Gehan and George Body Surface Area Formula
Gehan and George
CL374442
Gehan and George BSA Formula
Gehan and George Body Surface Area Formula
Therapeutic or Preventive Procedure
Procedure_Has_Completely_Excised_Anatomy only Nipple
C0024884
Radical Mastectomy
Procedure_Has_Excised_Anatomy only 'Pectoralis Major'
Procedure_Has_Excised_Anatomy only 'Pectoralis Muscle'
Procedure_Has_Excised_Anatomy only 'Pectoralis Minor'
Radical Mastectomy
Procedure_Has_Completely_Excised_Anatomy only Breast
<def-source>NCI-GLOSS</def-source><def-definition>(RAD-ih-kal mas-TEK-toe-mee) Surgery for breast cancer in which the breast, chest muscles, and all of the lymph nodes under the arm are removed. For many years, this was the operation most used, but it is used now only when the tumor has spread to the chest muscles. Also called the Halsted radical mastectomy.</def-definition>
Procedure_May_Have_Excised_Anatomy some 'Axillary Lymph Node'
Mastectomy
owl:Class
Procedure_Has_Completely_Excised_Anatomy only 'Mammary Gland'
C15279
Removal of the breast, pectoral muscles, axillary lymph nodes, and associated skin and subcutaneous tissue (from MeSH).
radical mastectomy
Radical Mastectomy
Halsted Radical Mastectomy
Procedure_Has_Completely_Excised_Anatomy only Areola
Radical Mastectomy
Electron Microscopy
Microscopy
Electron Microscopy
C16854
C0026019
owl:Class
Electron Microscopy
Electron Microscopy
Laboratory Procedure
Any form of microscopy in which the interactions of electrons with the specimens are used to provide information about the final structure of that specimen.
CL378249
Nutrition, Calories
calorie
Role of caloric intake in cancer causation or prevention and in general health.
C15646
Nutrition, Calories
Nutrition, Dietary Components
Nutrition, Calories
Nutrition, Calories
Research Activity
owl:Class
<def-source>NCI-GLOSS</def-source><def-definition>A measurement of the energy content of food. The body needs calories as "fuel" to perform all of its functions, such as breathing, circulating the blood, and physical activity. When a person is sick, their body may need extra calories to fight fever or other problems.</def-definition>
Aspiration Biopsy
owl:Class
Diagnostic Procedure
Needle Biopsy
Biopsy
Needle Biopsy
C0005560
needle biopsy
C15190
Puncture Biopsy
<def-source>NCI-GLOSS</def-source><def-definition>The removal of tissue or fluid with a needle for examination under a microscope.</def-definition>
Needle Biopsy
The removal of a tissue sample using a needle, for microscopic examination.
Needle Biopsy
Loop Electrosurgical Excision
Loop Electrosurgical Excision
Loop Electrosurgical Excision
owl:Class
Uses a thin, low-voltage electrified wire loop to cut out a thin layer of abnormal tissue; generally used to remove abnormal cells on the surface of the cervix.
Excision
Loop Electrosurgical Excision
LEEP
Therapeutic or Preventive Procedure
C51760
Loop Electrosurgical Excision Procedure
CL355220
C53327
Estimation
owl:Class
Research Activity
Statistical Estimation
C0681916
Statistical Estimation
A statistical procedure for assigning a plausable value to a parameter based on measured/empirical data.
Statistical Technique
Statistical Estimation
Statistical Estimation
<def-source>NCI-GLOSS</def-source><def-definition>(plas-ma-fer-EE-sis) The process of separating certain cells from the plasma in the blood by a machine; only the cells are returned to the person. Plasmapheresis can be used to remove excess antibodies from the blood.</def-definition>
Plasmapheresis
C0032113
Therapeutic Plasma Exchange
Plasmapheresis
Pheresis
Plasmapheresis
Therapeutic or Preventive Procedure
<def-source>MSH2001</def-source><def-definition>Removal of plasma and replacement with various fluids, e.g., fresh frozen plasma, plasma protein fractions (PPF), albumin preparations, dextran solutions, saline. Used in treatment of autoimmune diseases, immune complex diseases, diseases of excess plasma factors, and other conditions.</def-definition>
Plasma Exchange
owl:Class
plasmapheresis
Therapeutic Plasmapheresis
C15304
Plasmapheresis
Ileectomy
CL354650
Ileectomy
Procedure_Has_Excised_Anatomy only Ileum
Ileectomy
Ileectomy
Therapeutic or Preventive Procedure
owl:Class
Surgical removal of part or all of the ileum.
Partial Small Intestine Resection
Excision of Ileum
Resection of Ileum
C51780
CDISC SDTM Laboratory Test Terminology by Name
The determination of the amount of aldosterone hormone present in a sample.
Aldosterone Measurement
C74841
Aldosterone Measurement
Aldosterone Measurement
CDISC SDTM Terminology
Aldosterone Measurement
owl:Class
Clinical Data Interchange Standards Consortium Terminology
<def-definition>A measurement of the aldosterone hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SEND Terminology
Aldosterone
ALDSTRN
Laboratory Procedure
C0373535
Hormone Measurement
CDISC SDTM Laboratory Test Terminology by Code
Fixed Beam
Fixed Beam Radiation
Therapeutic or Preventive Procedure
Stationary Beam Radiation Therapy
Stationary Beam Radiation Therapy
Stationary Beam Radiation Therapy
C60646
Electron Beam Therapy
Radiation therapy without displacement of one or more mechanical axes relative to the patient during irradiation.
Fixed Beam Radiation Therapy
Stationary Beam Radiation
owl:Class
Stationary Beam Radiation Therapy
CL360532
Hybrid Modeling
C75362
Hybrid Modeling
CL384641
Hybrid Modeling
owl:Class
Hybrid Modeling
Research Activity
Modeling
The integration of both discrete and continuum modeling techniques in representing distinct dynamics and topographic regions of a system.
Medical Examination
Pain Assessment
The evaluation of pain complaints. Measurements should be objective on the part of the practitioner, based on subjective information from the patient. Measurements may also be indirect, by such assessments as respiratory rate and effort, withdrawal, guarding, or other appropriate assessment techniques.
Pain Assessment
Diagnostic Procedure
Pain Assessment
Pain Measurement
C0030198
Pain Assessment
owl:Class
C20992
Matrix Metalloproteinase 8 Measurement
C80196
Matrix Metalloproteinase 8 Measurement
Matrix Metalloproteinase 8 Measurement
Laboratory Procedure
owl:Class
The determination of the amount of matrix metalloproteinase 8 present in a sample.
Matrix Metalloproteinase 8 Measurement
Protein or Enzyme Type Measurement
Red Meat Consumption
C20046
Red Meat Consumption
A risk factor for colorectal, stomach, and pancreatic cancer.
Red Meat Consumption
CL014704
Red Meat Consumption
owl:Class
Dietary Practices
Individual Behavior
An immunohistochemical staining method to identify copper deposits in the liver, such as in Wilson's Disease, which is a genetic disorder of copper overload.
CL101868
Wison's Stain
Special Histology Staining Method
Wilson's Staining Method
Wilson's Staining Method
Laboratory Procedure
Wilson's Staining Method
C28414
Wilson's Staining Method
owl:Class
Wilson's Staining Method
Wison's Staining Method
Wilson's Stain
Modified Wright Stain
Direct Antiglobulin Test
Direct Antiglobulin Test
owl:Class
Immunology Test
Direct Antiglobulin Test
C81974
A measurement of the antibody or complement-coated erythrocytes in a blood specimen in vivo.
Direct Antiglobulin Test
First Line Treatment
First-Line Treatment
First Line Therapy
owl:Class
First-Line Therapy
Therapeutic Procedure
CL335260
Therapeutic or Preventive Procedure
C45792
First-Line Therapy
The preferred standard treatment for a particular condition.
First-Line Therapy
First-Line Therapy
Extraordinary Opportunities for Investment
owl:Class
Extraordinary Opportunities for Investment
Extraordinary Opportunities for Investment
Research areas of exceptional promise in the cancer field. To qualify as extraordinary opportunities these research initiatives must: Respond to important recent developments in knowledge and technology; Offer approaches to cancer research beyond the size, scope, and funding of our current research activities; Be implemented with specific, defined investments; Be described in terms of achievable milestones, with clear consequences for not investing; and Promise advances for making progress against all cancers. (from 2001 Bypass Budget)
Extraordinary Opportunities in Cancer Research
CL008663
Research Activity
Extraordinary Opportunities for Investment
Cancer Research
C16088
C15684
Hyperthermic Perfusion
Hyperthermic Perfusion
Perfusion
owl:Class
hyperthermic perfusion
CL031822
Therapeutic or Preventive Procedure
Hyperthermic Perfusion
<def-source>NCI-GLOSS</def-source><def-definition>A procedure in which a warmed solution containing anticancer drugs is used to bathe, or is passed through the blood vessels of, the tissue or organ containing the tumor.</def-definition>
Hyperthermic Perfusion
CL000735
Population Intervention
Population Intervention
Population Intervention
Health Care Activity
Population Intervention
Behavioral, Psychological or Informational Intervention
C15837
owl:Class
C18796
CL000397
Five-A-Day Program
Health Care Activity
Educational Intervention
A national initiative to increase consumption of fruits and vegetables by all Americans to 5 to 9 servings a day. The program seeks to do this by increasing public awareness of the importance of eating 5 to 9 servings of fruits and vegetables every day for better health,providing consumers with specific information about how to include more servings of fruits and vegetables into their daily routines, and increasing the availability of fruits and vegetables at home, school, work, and other places where food is served. Founded in 1991 as a partnership between the National Cancer Institute (NCI) and the Produce for Better Health Foundation, 5 A Day is the nation's largest public/private partnership for nutrition.
Five-A-Day Program
Five-A-Day Program
owl:Class
Five-A-Day Program
5-A-Day Program
Chromosome 5q31.1 Deletion Measurement
Chromosome 5q31.1 Deletion Measurement
Chromosome 5q31.1 Deletion Measurement
Cytogenetic Analysis
C79612
owl:Class
Laboratory Procedure
Chromosome 5q31.1 Deletion Measurement
Chiropractic Therapy
Chiropractic Medicine
C0008138
owl:Class
C15204
An alternative medical system that focuses on the relationship between bodily structure (primarily that of the spine) and function, and how that relationship affects the preservation and restoration of health. Chiropractors use manipulative therapy as an integral treatment tool.
Therapeutic or Preventive Procedure
Chiropractic Therapy
Massage and Body Work
Chiropractic Therapy
Chiropractic Therapy
Chiropractic
Rheumatoid Factor
Laboratory Procedure
CDISC SDTM Terminology
The determination of the amount of rheumatoid factor antibody present in a sample.
RF
CDISC SDTM Laboratory Test Terminology by Name
Clinical Data Interchange Standards Consortium Terminology
Rheumatoid Factor Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the rheumatoid factor antibody in a biological specimen.</def-definition>
CDISC SDTM Laboratory Test Terminology by Code
Immunology Test
CDISC SEND Terminology
Rheumatoid Factor Measurement
Rheumatoid Factor Measurement
C0553736
Rheumatoid Factor Measurement
CDISC
C74717
owl:Class
Microscopy, Phase-Contrast
A simple non-quantitative form of interference microscopy of great utility in visualising live cells. Small differences in optical path length due to differences in refractive index and thickness of structures are visualised as differences in light intensity.
Phase-Contrast Microscopy
C0026024
Phase-Contrast Microscopy
C16857
Light Microscopy
Phase-Contrast Microscopy
Laboratory Procedure
Phase-Contrast Microscopy
owl:Class
Radiotherapy using radioactive particles that deposit a high amount of energy by radiation per unit length of travel.
owl:Class
Radiotherapy-High LET
Radiotherapy, High Linear Energy Transfer
Local Therapy
CL000825
Radiation Therapy
High-LET Radiotherapy
High-LET Radiotherapy
High-LET Radiotherapy
Therapeutic or Preventive Procedure
C15849
High-LET Radiotherapy
Update
CL052785
owl:Class
Make current; supply with recent information or technology.
Update
Occupational Activity
Action
Update
Update
C25710
lymph node excision
excision of the lymph node
<def-source>NCI-GLOSS</def-source><def-definition>A surgical procedure in which the lymph nodes are removed and examined to see whether they contain cancer. For a regional lymph node dissection, some of the lymph nodes in the tumor area are removed; for a radical lymph node dissection, most or all of the lymph nodes in the tumor area are removed. Also called lymph node dissection.</def-definition>
lymphadenectomy
<def-source>NCI-GLOSS</def-source><def-definition>(limf node dis-EK-shun) A surgical procedure in which lymph nodes are removed and examined to see whether they contain cancer. Also called lymphadenectomy.</def-definition>
Procedure_Has_Excised_Anatomy only 'Lymph Node'
Surgical Procedure by Site or System
Diagnostic Procedure
owl:Class
lymph node dissection
Lymphadenectomy
Lymphadenectomy
Dissection
C0024203
Lymph Node Dissection
Therapeutic or Preventive Procedure
Lymphadenectomy
C15275
Surgical removal of lymph nodes, usually done to assess the spread of cancer.
Lymphadenectomy
Immunopotentiation Therapy
Therapeutic or Preventive Procedure
CL370836
Immunopotentiation Therapy
Immunopotentiation Therapy
owl:Class
Immunotherapy
Immunopotentiation Therapy
C66887
Functional Concept
The act of taking part in an activity.
Participation
Participation
Participating
Participation
C25608
owl:Class
C0679823
Participation
Action
The commercial processes involved in promoting and selling and distributing a product or service.
Marketing
owl:Class
C53292
Activity
Action
Marketing
Marketing
Marketing
C0024826
CL016064
Health Care Related Organization
Cancer Care Outcomes Research and Surveillance Consortium
A funding project supporting research towards measuring the quality of cancer care in the United States. It is to be a five-year project (starting which will support prospective cohort studies on 10,000 patients with newly diagnosed lung or colorectal cancers. The project is designed to increase the knowledge of the relationship between cancer care practices in the general population and patient outcomes including survival and quality of life.
C16190
Cancer Care Outcomes Research and Surveillance Consortium
CanCORS
Cancer Care Outcomes Research and Surveillance Consortium
Cancer Surveillance Project
owl:Class
Cancer Care Outcomes Research and Surveillance Consortium
<def-source>CDISC</def-source><def-definition>A measurement of the antibody reaction of a biological specimen to the either the HIV-1 or HIV-2 virus.</def-definition>
HIV Measurement
CDISC SEND Terminology
HIV-1 HIV-2 Antibody Measurement
CDISC
Laboratory Procedure
owl:Class
CDISC SDTM Laboratory Test Terminology by Name
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Terminology
HIV-1 HIV-2 Antibody Measurement
CDISC SDTM Laboratory Test Terminology by Code
HIV-1 HIV-2 Antibody Measurement
HIV-1/2 Antibody
HIV-1 HIV-2 Antibody Measurement
HIV12AB
CL384390
The determination of the antibody reaction of a sample to the HIV-1 or HIV-2 virus.
C74714
CDISC SDTM Laboratory Test Terminology by Name
The determination of the ratio of lymphocytes compared to leukocytes in a blood sample. The measurement may be expressed as a ratio or percentage.
Clinical Data Interchange Standards Consortium Terminology
LYMLE
Lymphocytes/Leukocytes
owl:Class
Laboratory Procedure
Lymphocyte to Leukocyte Ratio
CDISC SDTM Laboratory Test Terminology by Code
Blood Cell Count Ratio Measurement
Lymphocyte to Leukocyte Ratio
Lymphocyte to Leukocyte Ratio
<def-definition>A relative measurement (ratio or percentage) of the lymphocytes to leukocytes in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC
Lymphocyte to Leukocyte Ratio
CL370231
CDISC SEND Terminology
CDISC SDTM Terminology
C64820
Pain Management Method
Pain Management Method
Pain Management Method
owl:Class
Therapeutic Procedure
C21123
CL102835
Pain Management Method
Therapeutic or Preventive Procedure
Artificial Insemination
Reproductive Technique
Therapeutic or Preventive Procedure
Artificial Insemination
Introduction of sperm into the female reproductive tract by artificial means in order to achieve fertilization.
C16739
Artificial Insemination
Artificial Insemination
C0021587
owl:Class
owl:Class
Newborn Behavioral Examination
The assessment of behavior in neonates.
C81314
Newborn Behavioral Examination
Newborn Screening
Newborn Behavioral Examination
Diagnostic Procedure
Newborn Behavioral Examination
Medical Examination
Classification
Other Imaging Modalities
Medical Imaging, Other
owl:Class
Other Imaging Modalities
Imaging methods not listed.
CL003824
Imaging Technique
Other Imaging Modalities
Other Imaging Modalities
C19343
Therapeutic or Preventive Procedure
Procedure_Has_Target_Anatomy only Perineum
Perineal Prostatectomy
C0194818
Prostatectomy
Procedure_May_Have_Partially_Excised_Anatomy some 'Vas Deferens'
Perineal Prostatectomy
owl:Class
perineal prostatectomy
<def-source>NCI-GLOSS</def-source><def-definition>(peh-rih-NEE-al pros-ta-TEK-toe-mee) Surgery to remove the prostate through an incision made between the scrotum and the anus.</def-definition>
Perineal Prostatectomy
C15400
Perineal Prostatectomy
Procedure_May_Have_Partially_Excised_Anatomy some 'Seminal Vesicle'
Fluoroscopy
Diagnostic Procedure
fluoroscopy
<def-source>NCI-GLOSS</def-source><def-definition>(floor-AHS-ko-pee) An x-ray procedure that makes it possible to see internal organs in motion.</def-definition>
Fluoroscopy
Examination of the tissues and deep structures of the body by x-ray, using the fluoroscope, a device that produces an image when x-rays strike a fluorescent screen.
Fluoroscopy
Radiography
Fluoroscopy
<def-source>MSH2001</def-source><def-definition>Production of an image when x-rays strike a fluorescent screen.</def-definition>
C0016356
owl:Class
C16588
A staining procedure to detect viral inclusion bodies, which are virus particles inside host cells. Orcein stains are used to detect the inclusion bodies, giving a "ground glass" appearance, and are visible with light microscopy.
Staining for Viral Inclusions, NOS
Staining for Viral Inclusions
Laboratory Procedure
Special Histology Staining Method
C23038
Staining for Viral Inclusions
owl:Class
Staining for Viral Inclusions
Staining for Viral Inclusions
C0200967
Stain for Viral Inclusions
Intellectual Product
C82458
Manufacturing Product Defect Manufacturing Defect LOEE
Regulatory Assessment
Manufacturing Product Defect Manufacturing Defect LOEE
Manufacturing Product Defect Manufacturing Defect LOEE
MANUFACTURING/PRODUCT DEFECT MANUFACTURING DEFECT (LOEE)
owl:Class
Manufacturing Product Defect Manufacturing Defect LOEE
Troponin I Measurement
owl:Class
Troponin I Measurement
CDISC SDTM Terminology
C0920210
Laboratory Procedure
CDISC
Protein or Enzyme Type Measurement
CDISC SEND Terminology
Clinical Data Interchange Standards Consortium Terminology
<def-source>CDISC</def-source><def-definition>A measurement of the actin binding troponin in a biological specimen.</def-definition>
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Laboratory Test Terminology by Code
TROPONI
Troponin I Measurement
Troponin I Measurement
Troponin I
C74749
The determination of the amount of troponin I present in a blood sample.
owl:Class
Idea or Concept
C50839
Diagnosis
Established Diagnosis
Established Diagnosis
Established Diagnosis
CL354553
The identification of a disease by its signs, symptoms and results of various diagnostic procedures. The final conclusion reached through this process is called an established diagnosis.
Established Diagnosis
Steroid Measurement
Nandrolone Measurement
C0524199
Nandrolone Measurement
Laboratory Procedure
owl:Class
Nandrolone Measurement
Nandrolone Measurement
The determination of the amount of nandrolone present in a sample.
C75377
<def-source>NCI-GLOSS</def-source><def-definition>(LAIR-in-JEK-tuh-mee) An operation to remove all or part of the larynx (voice box).</def-definition>
Laryngectomy
Therapeutic or Preventive Procedure
Head and Neck Surgery
laryngectomy
Laryngectomy
Surgery to remove part or all of the larynx.
Procedure_Has_Excised_Anatomy only Larynx
Laryngectomy
owl:Class
C15267
C0023065
Laryngectomy
Peptide Synthesis
CL330064
Molecular Analysis
Laboratory Procedure
owl:Class
Peptide Synthesis
C16966
Peptide Synthesis
The sequential formation of peptide bonds between amino acids
Peptide Synthesis
owl:Class
Transplant Conditioning
Transplant Conditioning
Administration of high doses of chemotherapy or radiation therapy, as well as immunosuppressive therapy, to a transplant recipient prior to a bone marrow or hematopoietic stem cell transplant. Conditioning destroys the patient's abnormal blood cells or cancer, as well as slows the patient's immune response against the donor bone marrow (graft rejection).
Transplant Conditioning
Transplant Conditioning
Therapeutic or Preventive Procedure
C64468
Therapeutic Procedure
CL370356
C21107
Previous Pain Treatment Assessment
Diagnostic Procedure
Previous Pain Treatment
Previous Pain Treatment Assessment
owl:Class
CL100630
Previous Pain Treatment Assessment
Pain Assessment
The extent to which previous pain treatments were successful and the treatment regimens used, including narcotics, alternative/complimentary treatments, etc.
Previous Pain Treatment Assessment
Management
owl:Class
The act of conducting, controlling or supervising something.
Management
C61372
Managing
Action
Managed
Activity
Management
Management
CL364094
owl:Class
Therapeutic or Preventive Procedure
Minimal Contact Treatment
Minimal interventions directed at individuals that do not involve a health care provider, such as self-help and telephone counseling.
Therapeutic Procedure
CL004002
Minimal Contact Treatment
Minimal Contact Treatment
C15998
Minimal Contact Treatment
pilot study
<def-source>NCI-GLOSS</def-source><def-definition>The initial study examining a new method or treatment.</def-definition>
C0031928
Research Activity
Pilot Study
Study
C15303
Pilot Study
owl:Class
Pilot Study
Pilot Study
<def-source>MSH2001</def-source><def-definition>Small-scale tests of methods and procedures to be used on a larger scale if the pilot study demonstrates that these methods and procedures can work.</def-definition>
Research Activity
C16012
owl:Class
Nutrition, Artificial Sweeteners
Nutrition, Artificial Sweeteners
Nutrition, Dietary Components
Nutrition, Artificial Sweeteners
CL004421
Study of artificial sweeteners as potential carcinogens and in relation to general health.
Nutrition, Artificial Sweeteners
Turbinectomy
CL354855
Turbinectomy
C51750
owl:Class
Turbinectomy
Total or partial excision of the turbinates.
Head and Neck Surgery
Therapeutic or Preventive Procedure
Turbinectomy
Procedure_Has_Target_Anatomy only 'Paranasal Sinus'
Age-Adjusted Incidence Rate
CL356810
Incidence Rate
Age-Adjusted Incidence Rate
owl:Class
Quantitative Concept
Age-Adjusted Incidence Rate
Age-Adjusted Incidence Rate
The rate of disease occurrence, or proportion of disease occurrences in a given population, during a specified time period, statistically modified to eliminate the effect of the various age distributions.
C53352
CL000378
Experimental Nutrition
Experimental Nutrition
C15805
Experimental Nutrition
owl:Class
Research Activity
Nutritional Study
Experimental Nutrition
owl:Class
C51499
CL355472
Right Radical Mastectomy
Procedure_Has_Completely_Excised_Anatomy only 'Right Breast'
Right Radical Mastectomy
Therapeutic or Preventive Procedure
Right Radical Mastectomy
Radical Mastectomy
Right Radical Mastectomy
Sampling
Sampling
Sampling
Action
The selection and obtaining of small representative quantities of biological material for the purpose of analysis; also, in biomedical statistics, sampling is the selection and implementation of statistical observations in order to estimate properties of an underlying population; also, in environmental science, the collection of representative specimens analyzed to characterize site conditions.
Sampling
owl:Class
C0870078
C25662
Activity
Diagnostic Procedure
APGAR Test
APGAR Test
owl:Class
Newborn Screening
APGAR Test
A test devised by Dr. Virginia Apgar to assess the overall health of a newborn upon birth. The test is administered at one and five minutes after birth and allows for the assignation of numerical values between zero and two for specific observations regarding skin color, pulse rate, reflex irritability, muscle tone and breathing.
C81230
Newborn Screening
APGAR Test
C81185
owl:Class
Amino Acid Ratio Measurement
Amino Acid Ratio Measurement
Amino Acid Ratio Measurement
The determination of the ratio of one amino acid compared to another amino acid present in a sample. The measurement may be expressed as a ratio or percentage.
Amino Acid Ratio Measurement
Laboratory Procedure
Amino Acid Measurement
Temproal Artery Biopsy
owl:Class
Biopsy of Temporal Artery
Biopsy of Temporal Artery
Procedure_Has_Partially_Excised_Anatomy only 'Temporal Artery'
Biopsy of Temporal Artery
C51932
Diagnostic Procedure
Removal of a portion of the temporal artery for microscopic examination.
Biopsy of Temporal Artery
CL355003
Biopsy
Research Activity
Nutrition, Alcohol
Nutrition, Alcohol
Nutrition, Alcohol
Nutrition, Alcohol
C15925
Role of alcoholic beverages in cancer causation or prevention and in general health.
Nutrition, Dietary Components
CL003174
owl:Class
Small Bowel Excision
C51510
owl:Class
Small Intestine: Excisions
Small Intestine Resection
Procedure_Has_Excised_Anatomy only 'Small Intestine'
Surgical removal of part or all of the small intestine.
CL354236
Small Bowel Resection
Small Intestine: Excision
Small Intestine Resection
Small Intestine Resection
Small Intestine Resection
Intestine Resection
Therapeutic or Preventive Procedure
Allergy Shot
Allergy Shot
C28814
Allergy Shot
owl:Class
Immunologic Desensitization
The injection of an allergen extract intended to increase resistance, tolerance, or immunity to the given allergens. When the allergen extract is administered in a series of increasing amounts the process is referred to as allergy therapy, immunotherapy or desensitization.
Allergy Shot
CL319671
Therapeutic or Preventive Procedure
C51581
C0192440
Therapeutic or Preventive Procedure
Billroth I Procedure
Billroth I Procedure
Procedure_Has_Target_Anatomy some Duodenum
owl:Class
Surgical removal of the lower part of the stomach with end-to-end anastomosis of the remaining segment of the stomach with the duodenum.
Subtotal Gastrectomy
Procedure_Has_Completely_Excised_Anatomy only 'Antrum Pylori'
Procedure_Has_Partially_Excised_Anatomy only Stomach
Procedure_Has_Completely_Excised_Anatomy only 'Pyloric Sphincter'
Billroth I Procedure
Billroth I Procedure
The science of simulating the motions of a system of particles. (Karplus and Petsko)
<def-source>CSP2000</def-source><def-definition>computer technique for predicting conformation of protein or other macromolecule by rotating all bonds so as to minimize free energy; in looser parlance, term may refer to intramolecular motion.</def-definition>
C0596957
Molecular Dynamics
C18097
owl:Class
Molecular Dynamics (MD) Simulation
Molecular Dynamics
Molecular Dynamics
Computer Modeling
Molecular Dynamics
Activity
Thaw
Laboratory Procedure
C48165
Action
Thaw
Thaw
CL343203
Thaw
The process whereby heat changes something from a solid to a liquid.
Thaw Technique
owl:Class
Linear Regression Body Surface Area Formula for Infants and Children
Linear Regression Body Surface Area Formula for Infants and Children
C0023733
C68651
Body Surface Area Formula
Linear Regression Body Surface Area Formula for Infants and Children
owl:Class
Linear Regression BSA Formula for Infants and Children
Linear Regression
Occupational Activity
The formula to calculate body surface area as described by John D. Current. It is mathematically defined as: BSA (m^2) = 1321 + 0.3433 x Weight(g)
Linear Regression Body Surface Area Formula for Infants and Children
CL032519
Central Line Management
management of central line
owl:Class
Central Line Management
Catheter Management
C15758
Central Line Management
Central Line Management
Therapeutic or Preventive Procedure
Fatty Acid Measurement
C80157
Laboratory Procedure
Fatty Acid Measurement
owl:Class
The determination of the amount of fatty acids present in a sample.
Fatty Acid Measurement
Chemistry Test
Fatty Acid Measurement
CL387712
Excision Repair Cross-Complementing 1 Messenger RNA Expression Measurement
Excision Repair Cross-Complementing 1 Messenger RNA Expression Measurement
owl:Class
C79093
Laboratory Procedure
ERCC1 Messenger RNA Expression Measurement
Excision Repair Cross-Complementing 1 Messenger RNA Expression Measurement
Excision Repair Cross-Complementing 1 Messenger RNA Expression Measurement
RNA Analysis
Reduction Mammoplasty
CL356026
Therapeutic or Preventive Procedure
Right Reduction Mammoplasty
Right Reduction Mammoplasty
Right Reduction Mammoplasty
C51616
Right Reduction Mammoplasty
Procedure_Has_Partially_Excised_Anatomy only 'Right Breast'
Surgery performed to reduce the size of the right breast.
owl:Class
Terrorism Research
Terrorism Research
Research Activity
owl:Class
Terrorism Research
Research Activity
CL053947
C26020
Terrorism Research
Sestamibi Scan
CL322436
Sestamibi Scan
owl:Class
Diagnostic Procedure
Sestamibi Scan
A nuclear imaging procedure which is performed to identify hyperparathyroidism. Sestamibi is a nuclear radiopharmaceutical which is bound to the radioactive isotope Tc99m. Tc99m-Sestamibi is taken up by both the thyroid gland and the parathyroid gland, and is also used in Nuclear Myocardial Perfusion Imaging.
Sestamibi Scan
Radionuclide Imaging
C38091
owl:Class
Cerebral Edema Management
management of cerebral edema
Cerebral Edema Management
C15371
Cerebral Edema Management
Cerebral Edema Management
Supportive Care
Therapeutic or Preventive Procedure
C0150165
Gastroscopy
Gastroscopy
Diagnostic Procedure
Gastroscopy
owl:Class
Endoscopic examination of the stomach.
Procedure_Has_Target_Anatomy only Stomach
Gastroscopy
Gastrointestinal Endoscopy
gastroscopy
C0017195
Therapeutic or Preventive Procedure
C16604
<def-source>NCI-GLOSS</def-source><def-definition>(gas-TRAHS-ko-pee) An examination of the inside of the stomach using a thin, lighted tube (called a gastroscope) passed through the mouth and esophagus.</def-definition>
owl:Class
Laboratory Procedure
Endocrine Test
CL105007
Chemistry Test
Endocrine Test
C74971
Endocrine Test
A laboratory procedure that tests the function of an endocrine organ and measures the amount of a hormone present in a sample.
Endocrine Test
owl:Class
Therapeutic or Preventive Procedure
Portacath Placement
Port-a-cath Placement
Portacath Placement
Portacath Placement
CL322429
Surgical Procedure by Method
C38080
Portacath Placement
Light Microscopy
Diagnostic Procedure
Microscopy
owl:Class
Light Microscopy
Light Microscopy
C0430389
Laboratory Procedure
Light Microscopy is a technique for producing visible images of structures or details which are too small to be otherwise seen by the human eye. It involves passing light transmitted through or reflected from the subject through a series of lenses to be detected directly by the eye, imaged on a photographic plate, or captured digitally.
Light Microscopy
C17995
owl:Class
C20828
Optical Coherence Tomography
Optical Coherence Tomography
Optical Coherence Tomography (OCT) combines the principles of ultrasound with the imaging performance of a microscope. OCT uses infrared light waves that reflect off the internal microstructure within the biological tissues. The frequencies and bandwidths of infrared light are orders of magnitude higher than medical ultrasound signals, resulting in greatly increased image resolution, 8-25 times greater than any existing modality. In addition to providing high-level resolutions for the evaluation of microanatomic structures OCT is also able to provide information regarding tissue composition.
Optical Coherence Tomography
Diagnostic Procedure
Optical Coherence Tomography
Diagnostic Imaging
C0920367
Organism Modification
Chemical-Induced Change
Research Activity
C22494
Chemical-Induced Change
Chemical
Chemically-Induced Change
Chemical-Induced Change
Chemical
Chemical-Induced Change
C1527218
owl:Class
Glutamic Acid Decarboxylase 2 Measurement
Glutamic Acid Decarboxylase 2 Measurement
The determination of the amount of glutamic acid decarboxylase 2 present in a sample.
C82016
Glutamic Acid Decarboxylase 2 Measurement
Protein or Enzyme Type Measurement
owl:Class
Glutamic Acid Decarboxylase 2 Measurement
Endomyocardial Biopsy
CL355097
owl:Class
Procedure_Has_Partially_Excised_Anatomy only Myocardium
Biopsy
Endomyocardial Biopsy
Endomyocardial Biopsy
Removal of myocardial tissue for microscopic examination, usually taken from the right heart using a transvenous approach.
Endomyocardial Biopsy
C51674
Diagnostic Procedure
C71584
Action
Load
Load
Activity
To fill or to place an object onto or into a structure or conveyence; in computer terms, to copy data into memory.
Load
CL378281
Load
Loading
Loaded
owl:Class
Gene Mapping, Human
CL000412
Molecular Biology Research Technique
Gene Mapping, Human
owl:Class
DNA Sequencing, Human Gene Mapping
Gene Mapping
Gene Mapping, Human
DNA Sequencing, Gene Mapping, Human
Gene Mapping, Human
Laboratory Procedure
Determination of the relative positions of human genes on a DNA molecule (chromosome or plasmid) and of the distance, in linkage units or physical units, between them.
C18804
CL000921
owl:Class
Establishing relationships with individuals who have similar social or professional interests for the purposes of expanding knowledge and professional/social interaction. (Glanz et al: Heath Behavior &amp; Health Education, 1990)
Social Networking
Social Behavior
Personal Behavior
Social Networking
Social Networking
C19035
Social Networking
MODIFY
Instruction Imperative
The act of alteration or modification; changed or altered in form or character.
CDISC Observation Class Terminology
Change
Modified
Action
Change
Change
Modification
C0392747
owl:Class
Qualitative Concept
Change
C25446
Changed
owl:Class
Removal of tissue from the palate for microscopic examination.
Biopsy of Mouth
Biopsy of Palate
Diagnostic Procedure
CL354444
C51639
Biopsy of Palate
Procedure_Has_Partially_Excised_Anatomy only Palate
Biopsy of Palate
Biopsy of Palate
Spiral CT
CL009731
C19905
Diagnostic Procedure
A type of computed tomography whereby images are taken at certain time points post contrast medium injection.
Phased Spiral CT
Phased Spiral CT
owl:Class
Phased Spiral CT
Phased Spiral CT
CL027933
Other Evaluation of Risk Factors
owl:Class
Other Evaluation of Risk Factors
Other Evaluation of Risk Factors
C20696
Health Care Activity
Evaluation of Risk Factors
Other Evaluation of Risk Factors
<def-source>CDISC</def-source><def-definition>A measurement of the glucose in a biological specimen.</def-definition>
C0202042
Glucose Plasma Concentration (GPC) measurement is an essential diagnostic modality for different types of carbohydrate metabolism derangements including diabetes mellitus. The disordered carbohydrate metabolism that underlies diabetes manifests as hyperglycemia. Plasma glucose concentrations in healthy individuals vary with age. Normal fasting plasma glucose intervals (in the morning after an overnight fast) in children are 3.3 - 5.6 mmol/L (60-100 mg/dL); adult range - 4.1- 5.9 mmol/L (74-106 mg/dL). GPCs are approximately 11% higher than whole blood if the hematocrit is normal. Glucose concentrations in heparinized plasma are reported to be 5% lower than in serum.
C41376
Glucose
Plasma Glucose Measurement
GLUC
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Code
CDISC
CDISC SDTM Terminology
Blood Chemistry Measurement
Laboratory Procedure
Plasma Glucose Measurement
CDISC SEND Terminology
owl:Class
Plasma Glucose Measurement
Plasma Glucose Measurement
CDISC SDTM Laboratory Test Terminology by Name
Therapeutic or Preventive Procedure
Therapeutic Thoracoscopic Surgery
Therapeutic Thoracoscopic Surgery
Therapeutic Thoracoscopic Surgery
C65004
Therapeutic Surgical Procedure
Therapeutic Thoracoscopic Surgery
owl:Class
CL370562
Thoracoscopic Surgery
Diagnostic Procedure
An ambulatory electrocardiography technique that records a continuous electrocardiographic rhythm pattern for 24 hours or more to detect heart arrhythmias.
owl:Class
C0013801
Holter Monitoring
Holter Monitor
Electrocardiography
Holter Electrocardiography
Holter Monitoring
C38064
Holter Monitoring
Holter Monitoring
owl:Class
C15575
Diagnostic Procedure
Screening for Lung Cancer
Screening for Lung Cancer
C0281477
Cancer Screening
lung cancer screening
lung cancer early detection
early detection of lung cancer
Screening for Lung Cancer
Screening for Lung Cancer
Hemipelvectomy
Therapeutic or Preventive Procedure
Hemipelvectomy
Orthopedic Surgical Procedure
Procedure_Has_Partially_Excised_Anatomy only Pelvis
C51580
owl:Class
CL354595
Hemipelvectomy
Hemipelvectomy
Laparoscopic Surgery
Diagnostic Laparoscopic Surgery
Diagnostic Laparoscopic Surgery
Diagnostic Surgical Procedure
CL370144
C64994
Diagnostic Procedure
owl:Class
Diagnostic Laparoscopic Surgery
Diagnostic Laparoscopic Surgery
Molecular Analysis
C19770
Molecular Analysis
A laboratory procedure that involves the study of tissues, cells, and fluids using DNA/RNA analysis techniques for the identification of characteristics and abnormalities at the molecular level.
Molecular Genetic Procedure
Molecular Genetic Analysis
Laboratory Procedure
CL008759
owl:Class
Molecular Analysis
Laboratory Procedure
Molecular Procedure
Molecular Analysis
Ureterostomy
C0041963
Procedure_Has_Target_Anatomy only Ureter
C15345
owl:Class
Ureterostomy
Ureterostomy
Ureterostomy
Therapeutic or Preventive Procedure
Urostomy
<def-source>MSH2001</def-source><def-definition>Surgical formation of an opening in the ureter for external drainage of the urine; cutaneous route utilizes a ureteral orifice emerging through the skin.</def-definition>
Ultrasound Imaging
A method of ultrasound imaging in which the ultrasound probe is pressed against the skin of the abdomen in order to create an image of the abdominal organs.
<def-source>NCI-GLOSS</def-source><def-definition>A procedure used to examine the organs in the abdomen. The ultrasound device is pressed firmly against the skin of the abdomen. Sound waves from the device bounce off tissues and create echoes. A computer uses the echoes to make a picture called a sonogram.</def-definition>
Diagnostic Procedure
Transabdominal Ultrasound
Transabdominal Ultrasound
Transabdominal Ultrasound
owl:Class
Transabdominal Ultrasound
transabdominal ultrasound
C71375
CL378173
TUS
Brain-Derived Neurotrophic Factor Measurement
Protein or Enzyme Type Measurement
The determination of the amount of brain-derived neurotrophic factor present in a sample.
C82004
Brain-Derived Neurotrophic Factor Measurement
owl:Class
Brain-Derived Neurotrophic Factor Measurement
Brain-Derived Neurotrophic Factor Measurement
Exclusion Criteria
C0680251
Exclusion Criteria
Medical and/or social characteristics that prevent a subject from being allowed to participate in a clinical study, as outlined in the study protocol.
CDISC SDTM Terminology
CDISC
Exclusion Criteria
C25370
CDISC SDTM Category for Inclusion And Or Exclusion Terminology
Functional Concept
<def-source>CDISC</def-source><def-definition>List of characteristics in a protocol, any one of which may exclude a potential subject from participation in a study. (CDISC glossary)</def-definition>
Clinical Data Interchange Standards Consortium Terminology
Exclusion Criteria
owl:Class
Clinical Trial Eligibility Criteria
EXCLUSION
owl:Class
Hepatitis B Surface Antibody Measurement
Immunology Test
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
Hepatitis B Surface Antibody Measurement
C0201478
C74711
The determination of the surface antibody reaction of a sample to the Hepatitis B virus.
CDISC
CDISC SDTM Laboratory Test Terminology by Code
HBSAB
<def-source>CDISC</def-source><def-definition>A measurement of the surface antibody reaction of a biological specimen to the Hepatitis B virus.</def-definition>
Hepatitis B Surface Antibody Measurement
Hepatitis B Surface Antibody Measurement
Laboratory Procedure
Hepatitis B Virus Surface Antibody
CDISC SDTM Terminology
CDISC
CDISC SDTM Terminology
Triiodothyronine Measurement
Triiodothyronine Measurement
Triiodothyronine
Laboratory Procedure
Triiodothyronine Measurement
The determination of the amount of free and bound triiodothyronine present in a sample.
Clinical Data Interchange Standards Consortium Terminology
T3
C74747
C0428419
owl:Class
CDISC SDTM Laboratory Test Terminology by Name
Hormone Measurement
CDISC SEND Terminology
Triiodothyronine Measurement
CDISC SDTM Laboratory Test Terminology by Code
<def-source>CDISC</def-source><def-definition>A measurement of the total (free and bound) triiodothyronine in a biological specimen.</def-definition>
Therapeutic Procedure
Enzyme Inhibitor Therapy
owl:Class
Therapeutic or Preventive Procedure
CL034871
Enzyme Inhibitor Therapy
C62720
Enzyme Inhibitor Therapy
Enzyme Inhibitor Therapy
owl:Class
Infrared Thermography
C62663
Diagnostic Imaging
Infrared Thermography
Infrared Thermography
CL365654
Infrared Thermography
Diagnostic Procedure
Research Activity
C53357
owl:Class
Statistical Modeling
CL356475
Joinpoint Model
Joinpoint Model
Joinpoint Model
Joinpoint Model
Whole Organism Analysis
C19125
CL001108
Whole Organism Analysis
Laboratory Procedure
Whole Organism Analysis
owl:Class
Histological techniques in which thin sections through the entire animal are used.
Whole Organism Analysis
Histological Procedure
Prosthetics Intervention
Supportive Care
owl:Class
C71315
Therapeutic or Preventive Procedure
Prosthetics Intervention
Prosthetics Intervention
Prosthetics Intervention
CL377713
Drainage
owl:Class
Drainage
Drainage
C0013103
Therapeutic Procedure
Drainage
C50434
Conceptual Entity
The systematic withdrawal of fluids and discharges from a wound, sore or cavity.
CDISC
Clinical Data Interchange Standards Consortium Terminology
<def-source>CDISC</def-source><def-definition>A subcategory of Phase III trials done near the time of approval to elicit additional findings. NOTE: Dossier review may continue while associated Phase IIIB trials are conducted. These trials may be required as a condition of regulatory authority approval.</def-definition>
Research Activity
CDISC SDTM Trial Phase Terminology
CDISC SDTM Terminology
Phase IIIb Trial
A type of Phase III trial executed near the time of approval to elicit additional findings. This type of trial may be required as a condition of regulatory authority approval.
owl:Class
Phase III Trial
Phase IIIb Trial
C49689
Phase IIIb Trial
3B
Phase IIIb Trial
Trial Phase IIIB
Trial Phase 3B
CL355670
Chemotherapy
Nucleotide Analog Chemotherapy
owl:Class
C15956
Therapeutic or Preventive Procedure
Nucleotide Analog Chemotherapy
Use of nucleotide analogs in cancer treatment.
Nucleotide Analog Chemotherapy
Nucleotide Analog Chemotherapy
CL003488
Clinical Data Interchange Standards Consortium Terminology
<def-source>CDISC</def-source><def-definition>A type of study designed to identify actions necessary to eliminate or reduce the risk to human life or well-being as a result of a particular medication or treatment regimen. (NCI)</def-definition>
CL354918
Adverse Effect Mitigation Study
owl:Class
CDISC
A type of study designed to identify actions necessary to eliminate or reduce the risk to human life or well-being as a result of a particular medication, treatment regimen, procedure, or any other medical intervention.
CDISC SDTM Terminology
Adverse Effect Mitigation Study
Adverse Effect Mitigation Study
Trial Indication Type
Research Activity
CDISC SDTM Trial Indication Type Terminology
C49655
MITIGATION
Adverse Effect Mitigation Study
<def-source>CDISC</def-source><def-definition>A measurement of the glutamate in a biological specimen.</def-definition>
CDISC
CDISC SEND Terminology
owl:Class
Protein or Enzyme Type Measurement
Glutamate Measurement
Clinical Data Interchange Standards Consortium Terminology
Glutamate
Glutamate Measurement
C74739
Glutamate Measurement
Laboratory Procedure
Glutamic Acid
CDISC SDTM Terminology
The determination of the amount of glutamate present in a sample.
GLUTAM
Glutamate Measurement
C0523665
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Laboratory Test Terminology by Code
Diagnostic Procedure
Removal of tissue from the pericardium for microscopic examination.
Biopsy of Pericardium
C51568
Biopsy of Pericardium
Pericardial Biopsy
CL354999
owl:Class
Procedure_Has_Partially_Excised_Anatomy only Pericardium
Biopsy
Biopsy of Pericardium
Biopsy of Pericardium
C15912
regional chemotherapy
CL002587
<def-source>NCI-GLOSS</def-source><def-definition>(kee-mo-THER-a-pee) Treatment with anticancer drugs directed to a specific area of the body.</def-definition>
Chemotherapy
Regional Chemotherapy
owl:Class
Regional Chemotherapy
Regional Chemotherapy
Regional Chemotherapy
Therapeutic or Preventive Procedure
Local Therapy
The determination of the ratio of creatine kinase MB compared to total creatine kinase present in a sample. The measurement may be expressed as a ratio or percentage.
C79441
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Name
Clinical Data Interchange Standards Consortium Terminology
Urine Protein Measurement
owl:Class
Creatine Kinase MB to Total Creatine Kinase Ratio Measurement
Creatine Kinase MB to Total Creatine Kinase Ratio Measurement
Laboratory Procedure
Creatine Kinase MB/Total Creatine Kinase
<def-definition>A relative measurement (ratio or percentage) of the MB-type creatine kinase to total creatine kinase in a biological specimen.</def-definition><def-source>CDISC</def-source>
Creatine Kinase MB to Total Creatine Kinase Ratio Measurement
CKMBCK
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
Creatine Kinase MB to Total Creatine Kinase Ratio Measurement
Anti-Saccharomyces cerevisiae Antibody Measurement
Anti-Saccharomyces cerevisiae Antibody Measurement
The determination of the amount of anti-Saccharomyces cerevisiae antibody present in a sample.
owl:Class
Anti-Saccharomyces cerevisiae Antibody Measurement
Anti-Saccharomyces cerevisiae Antibody Measurement
C81976
Immunology Test
C20035
CL014473
owl:Class
Diagnostic Procedure
Fluorescence Bronchoscopy
Fluorescence bronchoscopy is based on the fact that normal tissue fluoresces differently than abnormal tissue when exposed to an appropriate wavelength of light and that this difference can be detected.
Fluorescence Bronchoscopy
Bronchoscopy
Fluorescence Bronchoscopy
Fluorescence Bronchoscopy
C65185
Complete Linkage Cluster Analysis
Complete Linkage Cluster Analysis
Complete Linkage Clustering
owl:Class
Complete Linkage
CL370685
Complete Linkage Cluster Analysis
Complete Linkage Cluster Analysis
Furthest Neighbor
Research Activity
A clustering method in which the distance between two clusters is determined by the greatest distance between any two objects in the different clusters (furthest neighbors).
Hierarchical Clustering
C61028
Serum Phosphate Measurement
Serum Phosphate Measurement
Phosphate Measurement
Serum Chemistry Measurement
Laboratory Procedure
A quantitative measurement of the amount of phosphate present in a sample of serum.
owl:Class
Serum Phosphate Measurement
Serum Phosphate Measurement
CL364121
Lab Tests
Tests
Laboratory Procedure
Laboratory Test
Any procedure that involves testing or manipulating a sample of blood, urine, or other body substance in a laboratory setting.
laboratory test
Newborn Screening
<def-source>NCI-GLOSS</def-source><def-definition>A medical procedure that involves testing a sample of blood, urine, or other substance from the body. Tests can help determine a diagnosis, plan treatment, check to see if treatment is working, or monitor the disease over time.</def-definition>
Intervention or Procedure
C25294
Test
Laboratory Procedure
Laboratory Procedure
Laboratory Procedure
C0022885
owl:Class
Lab Test
Laboratory Procedure
Work
Service
Work, or a product of that work, done by one person or group that benefits another.
Activity
CL343367
Service
Service
Service
C47920
owl:Class
Health Care Activity
Counseling
C61547
C0010210
Counseling
counseling
Counseling
The act of receiving professional guidance in resolving personal conflicts and emotional problems.
owl:Class
Behavioral, Psychological or Informational Intervention
Counseling
<def-source>NCI-GLOSS</def-source><def-definition>(KOWN-suh-ling) The process by which a professional counselor helps a person cope with mental or emotional distress, and understand and solve personal problems.</def-definition>
Smear
Smear
CL370610
Activity
C65126
Instruction Imperative
Smear
owl:Class
Spread
Smear
Molecular Biology Research Technique
CDR3 Spectratyping
A laboratory procedure that analyzes the genetic profile of the T-cell receptor variable complementary determining region 3 (CDR3) for an individual. The genetic sequence for CDR3 is amplified using the polymerase chain reaction and specific primers.
owl:Class
Laboratory Procedure
CDR3 Spectratyping
Complementary Determining Region 3 Spectratyping
CDR3 Spectratyping
C74541
CDR3 spectratyping can be used to both determine the extent of a patient's immune system disorder or analyze immune reconstitution for a patient following a transplant or chemotherapy.
CDR3 Spectratyping
Polymerase Chain Reaction
CL384131
Creatine Kinase Measurement
Protein or Enzyme Type Measurement
C0201973
Clinical Data Interchange Standards Consortium Terminology
CK
Creatine Kinase
Creatine Kinase Measurement
Creatine Kinase Measurement
CDISC
<def-source>CDISC</def-source><def-definition>A measurement of the total creatine kinase in a biological specimen.</def-definition>
C64489
A quantitative measurement of the amount of creatine kinase present in a sample.
CDISC SDTM Laboratory Test Terminology by Name
owl:Class
Creatine Kinase Measurement
CDISC SEND Terminology
CDISC SDTM Terminology
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Code
Cystoscopy
Cystoscopy
Cystoscopy
C0010702
C16482
Endoscopic examination of the urinary bladder or urethra.
Diagnostic Procedure
Endoscopic Procedure
cystoscopy
Procedure_Has_Target_Anatomy only Bladder
Therapeutic or Preventive Procedure
<def-source>NCI-GLOSS</def-source><def-definition>(sist-OSS-ko-pee) Examination of the bladder and urethra using a thin, lighted instrument (called a cystoscope) inserted into the urethra. Tissue samples can be removed and examined under a microscope to determine whether disease is present.</def-definition>
owl:Class
Cystoscopy
Real-Time Contrast-Enhanced Ultrasonography
CL370345
Real-Time Contrast-Enhanced Ultrasonography
C64866
Diagnostic Procedure
owl:Class
Real-Time Contrast-Enhanced Ultrasonography
Ultrasound Imaging
Real-Time Contrast-Enhanced Ultrasonography
C74790
CDISC SDTM Terminology
Luteinizing Hormone Measurement
CDISC SDTM Laboratory Test Terminology by Code
LH
CDISC SEND Terminology
Luteinizing Hormone
owl:Class
Clinical Data Interchange Standards Consortium Terminology
C0202123
Laboratory Procedure
Luteinizing Hormone Measurement
Luteinizing Hormone Measurement
CDISC
Luteinizing Hormone Measurement
Hormone Measurement
The determination of the amount of luteinizing hormone present in a sample.
<def-source>CDISC</def-source><def-definition>A measurement of the luteinizing hormone in a biological specimen.</def-definition>
CDISC SDTM Laboratory Test Terminology by Name
Laboratory Procedure
Conformation Dependent Mutation Detection
CL015632
Polymorphism, single-stranded conformational, detection. Altered migration of single-stranded DNA molecules in non-denaturing gels based upon 3-D conformation. Uses PCR and/or restriction enzymes to generate short dsDNA molecules spanning a sequence of interest. The dsDNA molecules are heat denatured, and then quickly cooled. Each ssDNA molecule will assume a secondary structure (conformation) dependent upon its unique sequence. Base mutations will often result in altered conformations, with altered mobilities, which can be visualized following separation in non-denaturing gels. (NCI/OSP)
Conformation Dependent Mutation Detection
Conformation Dependent Mutation Detection
C20064
Conformation Dependent Mutation Detection
Polymorphism Analysis
owl:Class
CL336541
Renal Complications Management
C62747
Renal Complications Management
Supportive Care
owl:Class
Renal Complications Management
Therapeutic or Preventive Procedure
Renal Complications Management
C16054
Drug Synthesis and Chemistry
Drug Synthesis and Chemistry
Drug Synthesis and Chemistry
Drug Synthesis and Chemistry
owl:Class
CL007298
Drug Synthesis
Drug Development
Occupation or Discipline
Activity
Action
CL360571
C60731
Advising
Advising
The act of giving information, suggestion, or recommendation to a group or individual.
Advising
owl:Class
Advising
Bonferroni Adjustment
Bonferroni Adjustment
Bonferroni Adjustment
Multiple Comparison Adjustment
owl:Class
CL364642
Quantitative Concept
C61594
Bonferroni Adjustment
Used in multiple comparison procedures to calculate an adjusted probability, alpha (a), of comparison-wise type I error from the desired probability aFW0 of family-wise type I error. The calculation guarantees that the use of the adjusted a in pairwise comparisons keeps the actual probability aFW of family-wise type I errors not higher than the desired level, as specified by aFW0.
C15378
Boron Neutron Capture Therapy
Boron Neutron Capture Therapy
Boron Neutron Capture Therapy
owl:Class
Therapeutic or Preventive Procedure
Boron Neutron Capture Therapy
Radiation Therapy
A type of radiation therapy in which the patient is given an intravenous boron infusion that is absorbed by tumor cells. Radiation is then directed at the boron, killing the tumor cells but not the surrounding normal tissue.
<def-source>NCI-GLOSS</def-source><def-definition>A type of radiation therapy. The person is given an intravenous infusion containing the element boron, which concentrates in the tumor cells. The person then receives radiation therapy with atomic particles called neutrons from a small research nuclear reactor. The radiation is absorbed by the boron, killing the tumor cells without harming normal cells.</def-definition>
C0162505
boron neutron capture therapy
Survivorship
C17177
Population-Based Statistic
Survival
Survival
owl:Class
Continuance of life or existence especially under adverse conditions; includes methods and philosophy of survival.
C0038952
Survivorship Issues
Conceptual Entity
Survival
Survival
Bite Cells
Bite Cell Count
owl:Class
Bite Cell Count
C74700
CDISC SDTM Laboratory Test Terminology by Code
Laboratory Procedure
Erythrocyte Count
<def-definition>A measurement of the bite cells (erythrocytes with the appearance of a bite having been removed, due to oxidative hemolysis) in a biological specimen.</def-definition><def-source>CDISC</def-source>
BITECE
CDISC SEND Terminology
CL384725
CDISC SDTM Laboratory Test Terminology by Name
Bite Cell Count
Bite Cell Count
CDISC SDTM Terminology
The determination of the number of bite cells present in a sample.
Clinical Data Interchange Standards Consortium Terminology
CDISC
Cytokeratin-8 Staining Method
An immunohistochemical technique to detect cytokeratin 8, an intermediate filament protein, using monoclonal antibody to cytokeratin 8. The antibody is useful in the detection of adenocarcinomas, mesotheliomas, and certain squamous epithelia-derived carcinomas. Specific combinations of cytokeratin peptides are associated with certain epithelial cells, and are therefore useful in the characterization of poorly differentiated carcinoma. The test is used as a clinically significant indicator in distinguishing carcinoma from malignant tumors of non-epithelial origin, such as lymphoma, sarcoma, and melanoma.
Cytokeratin 8 Staining Method
Special Histology Staining Method
CK8
C1527157
Laboratory Procedure
Cytokeratin-8 Staining Method
Cytokeratin-8 Staining Method
owl:Class
Cytokeratin-8 Staining Method
Cytokeratin 8
Cytokeratin 8 Staining Method
C23026
CL378592
C72648
A mathematical method for calculating a relatedness score for genes.
Gene Distance Metric
Gene Distance Metric
Distance Metric
Statistical Technique
Gene Distance Metric
owl:Class
Gene Distance Metric
Quantitative Concept
C15599
Hormone Replacement Therapy
Therapeutic or Preventive Procedure
In women, treatment with sex hormones is indicated for a number of reasons, including menopause, partial or full hysterectomy, or amenorrhea. NHLBI of NIH stopped early a major clinical trial of the risks and benefits of combined estrogen and progestin in healthy menopausal women due to an increased risk of invasive breast cancer and lack of overall benefit. Though with fewer cases of hip fractures and colon cancer, combined estrogen and progestin leads to an increased risk of invasive breast cancer, coronary heart disease, stroke, and pulmonary embolism in healthy menopausal women on estrogen plus progestin compared to those taking placebo pills. However, a separate study of estrogen alone in women who had a hysterectomy before receiving therapy continues unchanged because, at this point, the balance of risks and benefits of estrogen alone is still uncertain. (http://www.nhlbi.nih.gov/new/press/02-07-09.htm and NCI)
C0282402
Hormone Replacement Therapy
Treatment with estrogens or estrogen/progesterone after menopause or ovariectomy to prevent pathological effects of decreased estrogen production.
Hormone Replacement Therapy
Endocrine Drug Therapy
Hormone Replacement Rx
Replacement Therapy
<def-source>NCI-GLOSS</def-source><def-definition>Hormones (estrogen, progesterone, or both) given to postmenopausal women or women who have had their ovaries surgically removed, to replace the estrogen no longer produced by the ovaries.</def-definition>
HRT
Hormone Replacement Therapy
owl:Class
hormone replacement therapy
Research Activity
LIBCSP
Long Island Breast Cancer Study
CL013992
owl:Class
Epidemiology Research
Long Island Breast Cancer Study Project
Health Care Activity
Long Island Breast Cancer Study
C16127
Long Island Breast Cancer Study
Long Island Breast Cancer Study
Cancer Causation Research
A study designed to conduct epidemiologic research on the role of environmental factors in the etiology of breast cancer in women who live in Nassau and Suffolk counties, New York. The US Congress has mandated the use of a case-control study and the Geographic Information System (GIS) database to study a list of environmental factors, including water quality, air pollution, electromagnetic fields, pesticides and other toxic chemicals, and hazardous and municipal waste. (from NIEHS Long Island Breast Cancer Study Project)
The multistudy effort to investigate whether exposure to certain environmental factors (water quality, air pollution, electromagnetic fields, pesticides and other toxic chemicals, hazardous and municipal waste, etc.) contribute to the increased risk of breast cancer. Project started in 1993 under Public Law 103-43 and is funded and coordinated by the National Cancer Institute and the National Institute of Environmental Health Sciences. The study is conducted in Suffolk, Nassau, and Schoharie counties in New York and in Tolland County, Conn. It includes more than 10 studies: epidemiologic studies, family breast and ovarian cancer registry, laboratory research, and the creation of a new research tool, a Geographic Information System.
Growth Hormone Measurement
Somatotropin Measurement
C0202056
Laboratory Procedure
C74792
The determination of the amount of somatotropin hormone present in a sample.
Somatotropin Measurement
owl:Class
Somatotropin Measurement
Somatotropin Measurement
C0018810
The number of heartbeats per unit of time, usually expressed as beats per minute.
Clinical Data Interchange Standards Consortium Terminology
Heart Rate
C49677
CDISC SDTM Vital Sign Terminology by Name
CDISC SDTM Terminology
Quantitative Concept
HR
CDISC SDTM Vital Sign Terminology by Code
Newborn Screening
owl:Class
Heart Rate
Vital Signs
Heart Rate
CDISC
<def-source>CDISC</def-source><def-definition>The number of heartbeats per unit of time, usually expressed as beats per minute. (NCI)</def-definition>
Heart Rate
Laboratory Procedure
Cellular Physiologic Testing
Physiologic Testing
owl:Class
Cellular Physiologic Testing
CL377548
Cellular Physiologic Testing
C71318
Cellular Physiologic Testing
Sperm Preservation
owl:Class
Sperm Preservation
Biologic Sample Preservation Procedure
Sperm Preservation
C17737
C0242500
Sperm Preservation
Laboratory Procedure
Methods for short or long term preservation of sperm cells, such as cryopreservation in liquid nitrogen. (NCI/OSP)
C16030
Carbogen Breathing
Carbogen Breathing
Therapeutic or Preventive Procedure
Increases the oxygenation of tumors thereby enhancing the effect of radiation therapy.
Biological Therapy
CL004795
owl:Class
Carbogen Breathing
Carbogen Breathing
Nipple Suction Aspiration
Nipple Discharge Aspiration
Nipple Discharge Aspiration
CL322426
Nipple Discharge Aspiration
An aspiration of nipple discharge using a fine needle to investigate the presence of disease.
C38076
Diagnostic Procedure
Diagnostic Procedure
Nipple Discharge Aspiration
owl:Class
Hematopoietic Stem Cell Mobilization
Hematopoietic Stem Cell Mobilization
C63494
Therapeutic or Preventive Procedure
Therapy Preparation
Hematopoietic Stem Cell Mobilization
owl:Class
Hematopoietic Stem Cell Mobilization
C0524864
CDISC Observation Class Terminology
Concomitant Therapy
Therapeutic Procedure
CONTRT
owl:Class
Concomitant Therapy
Concomitant Therapy
Concomitant Therapy
CL356999
Therapeutic or Preventive Procedure
C53630
FDA
C61012
Fluorescence-Guided Surgery
Surgical Procedure by Method
Fluorescence-Guided Surgical Procedure
CL364082
Fluorescence-Guided Surgery
Fluorescence-Guided Surgery
Fluorescence-Guided Surgery
owl:Class
Therapeutic or Preventive Procedure
Receptor-Targeted Chemotherapy
Receptor-Targeted Chemotherapy
Chemotherapy
Receptor-Targeted Chemotherapy
Receptor-Targeted Chemotherapy
Therapeutic or Preventive Procedure
C71589
owl:Class
CL378323
Slit-lamp Examination
Diagnostic Procedure
Slit-lamp Examination
Slit-lamp Examination
owl:Class
Eye Examination
C75583
Slit-lamp Examination
Examination of the anterior segment of the eye using a medical instrument called a slit lamp.
C0419360
Cabot Ring Count
C74702
<def-source>CDISC</def-source><def-definition>A measurement of the Cabot rings (red-purple staining, threadlike, ring or figure 8 shaped filaments in an erythrocyte) in a biological specimen.</def-definition>
Erythrocyte Count
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
CABOT
Clinical Data Interchange Standards Consortium Terminology
Cabot Ring Count
Cabot Ring Count
Cabot Ring Count
CDISC SEND Terminology
Cabot Rings
Laboratory Procedure
CL384746
The determination of the number of Cabot rings present in a sample.
CDISC
owl:Class
Therapeutic or Preventive Procedure
Surgical removal of part or all of the colon, part or all of the anus, and all of the rectum.
CL353635
owl:Class
Proctocolectomy
Proctocolectomy
Procedure_Has_Completely_Excised_Anatomy only Rectum
Proctocolectomy
Procedure_Has_Excised_Anatomy only Colon
Procedure_Has_Excised_Anatomy only Anus
Proctocolectomy
Digestive System Surgery
C51635
Iron stain is the classic method for demonstrating iron in tissues. Hemosiderin (storage iron granules) may be present in areas of old hemorrhage or be deposited in tissues with iron overload. Prussian blue stain is used for the demonstration of ferric iron in the tissue sections. This stain can aid in identifying hemochromatosis and hemosederosis where abnormal large deposits of iron may be seen. In the prussian blue staining, the sections are treated with an acidic solution of potassium ferrocyanide and any ferric iron present reacts to form an insoluble bright blue pigment called Prussian blue.
Iron Staining Method
CL100937
Iron
Special Histology Staining Method
Iron Staining Method
Iron Staining Method
C23016
owl:Class
Laboratory Procedure
Iron Staining Method
Iron Staining Method
Usually Prussian blue
CDISC SEND Terminology
C64495
Chloride Measurement
CDISC SDTM Laboratory Test Terminology by Code
Laboratory Procedure
A quantitative measurement of the amount of chloride present in a sample.
owl:Class
Electrolyte Measurement
Chloride
Chloride Measurement
CDISC SDTM Terminology
Chloride Measurement
Clinical Data Interchange Standards Consortium Terminology
C0201952
Chloride Measurement
CDISC SDTM Laboratory Test Terminology by Name
<def-source>CDISC</def-source><def-definition>A measurement of the chloride in a biological specimen.</def-definition>
CDISC
CL
Protein or Enzyme Type Measurement
Glucose-6-Phosphate Dehydrogenase Measurement
C80184
Glucose-6-Phosphate Dehydrogenase Measurement
Glucose-6-Phosphate Dehydrogenase Measurement
The determination of the amount of glucose-6-phosphate dehydrogenase present in a sample.
Laboratory Procedure
owl:Class
Glucose-6-Phosphate Dehydrogenase Measurement
owl:Class
Non-Invasive Cancer Detection
Cancer Detection
C16107
Non-Invasive Cancer Detection
Non-Invasive Detection
Non-Invasive Cancer Detection
CL008767
Non-Invasive Cancer Detection
Methods of detection which do not require penetration of the body or body openings.
Diagnostic Procedure
Research Technique
Microtechnique
CL026564
owl:Class
Laboratory techniques required for preparation of tissues for light microscopy/histological analysis to study the microscopic structure of animal tissues, including their cellular composition, origin, differentiation, function and arrangement into organs.
C20369
Microtechnique
Microtechnique
Microtechnique
Laboratory Procedure
Dental Prophylaxis
Dental Prophylaxis
owl:Class
Treatment for the prevention of periodontal diseases or other dental diseases by the cleaning of the teeth in the dental office using the procedures of dental scaling and dental polishing.
Dental Prophylaxis
Therapeutic or Preventive Procedure
C0011393
Dental Procedure
C62548
Dental Prophylaxis
Magnetic Resonance Spectroscopic Imaging
Magnetic Resonance Spectroscopic Imaging
Magnetic Resonance Spectroscopic Imaging
<def-source>NCI-GLOSS</def-source><def-definition>MRSI. A noninvasive imaging method that provides information about cellular activity (metabolic information). It is used along with magnetic resonance imaging (MRI) which provides information about the shape and size of the tumor (spatial information). Also called 1H-nuclear magnetic resonance spectroscopic imaging and proton magnetic resonance spectroscopic imaging.</def-definition>
Magnetic resonance spectroscopy is a noninvasive imaging technique that acts as a complement to conventional imaging of brain tumors in order to improve the sensitivity and specificity of the diagnostic process. This technique operates by exciting and recording signals from a range of magnetic resonance frequencies, allowing the identification and quantification of several biologically significant molecules containing proton groups that resonate in the appropriate frequency range. The technique facilitates observation of the spatial distribution of metabolic patterns over a region of interest and surrounding tissue at a high spatial resolution.
C29934
magnetic resonance spectroscopic imaging
Proton Magnetic Resonance Spectroscopic Imaging
1H- Nuclear Magnetic Resonance Spectroscopic Imaging
CL320096
owl:Class
Magnetic Resonance Imaging
Diagnostic Procedure
Magnetic Resonance Spectroscopic Imaging
owl:Class
Health Care Delivery
The provision of medical care.
Health Care Delivery
Care Delivery
Health Care Delivery
Healthcare Activity
Health Services Delivery, Other
Health Care Delivery
C0011211
Healthcare Delivery
Health Care Activity
C15219
Validation of Clinical Utility of Markers
C15874
Validation of Clinical Utility of Markers
Validation of Clinical Utility of Markers
Health Care Activity
Validation
Validation of Clinical Utility of Markers
owl:Class
CL001077
Diagnostic Procedure
C19341
Imaging Technique
Multimodal Imaging
Multimodal Imaging
owl:Class
Multimodal Imaging
CL003822
Multimodal Imaging
Multimodality
Simultaneous use of more than one imaging technique.
C51603
Removal of tissue from the mediastinum for microscopic examination, using an endoscope.
Mediastinal Biopsy
Procedure_Has_Partially_Excised_Anatomy only Mediastinum
Diagnostic Procedure
Mediastinal Biopsy
Endoscopic Biopsy
CL354720
Mediastinal Biopsy
Mediastinal Biopsy
owl:Class
Methoxsalen With Ultraviolet A Therapy
Phototherapy
Strong evidences have indicated causal association between 8-methoxypsoralen with UVA (PUVA) treatment and non-melanocytic skin patients with psoriasis. 8-Methoxypsoralen alone did not alter the incidence of new skin cancer development in a 2-year study. In a large number of studies, 8-Methoxypsoralen in combination with ultraviolet A radiation induced chromosomal aberrations, sister chromatid exchanges, mutation, DNA damage and DNA cross-links in human cells in vitro. This treatment is classified as carcinogenic to Human by IARC. (NCI05)
Therapeutic or Preventive Procedure
8-Methoxypsoralen Plus Ultraviolet Radiation
Methoxsalen With Ultraviolet A Therapy
Ultraviolet Light Therapy Using Methoxsalen
Methoxsalen With Ultraviolet A Therapy
Methoxsalen With Ultraviolet A Therapy
CL334109
owl:Class
PUVA
C44398
<def-source>NCI-GLOSS</def-source><def-definition>Any method that uses cold temperature to treat disease.</def-definition>
Therapeutic Procedure
C40030
Cryotherapy
The therapeutic use of cold or refrigeration in medicine.
Cryotherapy
Therapeutic or Preventive Procedure
Cryotherapy
C0010412
Cryotherapy
cryotherapy
owl:Class
Laboratory Procedure
Hormone Measurement
Endocrine Test
The determination of the amount of hormone present in a sample.
Hormone Measurement
Protein or Enzyme Type Measurement
C0441683
C74742
Hormone Measurement
Hormone Measurement
owl:Class
Radiation Therapy
Radiation Non-Ionizing, Radiotherapy
C15847
Local Therapy
Radiation Non-Ionizing, Radiotherapy
Radiation Non-Ionizing, Radiotherapy
CL000812
owl:Class
Therapeutic or Preventive Procedure
Radiation Non-Ionizing, Radiotherapy
Gel Dosimetry
Gel Dosimetry
owl:Class
CL015041
Radiation Dosimetry
C16184
Gel Dosimetry
Laboratory Procedure
Gel Dosimetry
Gel dosimetry involves filling a model of a body part, such as the head, neck or breast, with a gel mixture. The gel-filled model (phantom) then undergoes MRI, CT, ultrasound, or radiation therapy, to gauge how effective the same procedure might be for the patient. Radiation alters the chemical structure of the gel, and the changes appear when scientists view a cross-section of the phantom on the computer screen. (from Medscape)
owl:Class
CL370847
Laser Therapy
C66918
Infrared Laser Therapy
Therapeutic or Preventive Procedure
Infrared Laser Therapy
Infrared Laser Therapy
Infrared Laser Therapy
owl:Class
CL370353
Titrate
C64630
Titrate
Titrate
Titrate
Activity
Instruction Imperative
Chemotherapy
C15981
Supportive Cancer Chemotherapy
Supportive Cancer Chemotherapy
Chemotherapy, Cancer, Supportive
Therapeutic or Preventive Procedure
Treatment designed to improve the health of a chemotherapy patient but that does not directly affect the tumor.
owl:Class
CL003836
Supportive Cancer Chemotherapy
Supportive Cancer Chemotherapy
<def-source>MSH2001</def-source><def-definition>Endoscopic surgical procedures performed with visualization via video transmission.</def-definition>
Video-Assisted Surgery
Imaging Guided Therapy
owl:Class
Video-Assisted Surgery
video-assisted surgery
video-assisted resection
Video-Assisted Surgery
C0677965
Video-Assisted Surgery
<def-source>NCI-GLOSS</def-source><def-definition>Surgery that is aided by the use of a video camera that projects and enlarges the image on a television screen.</def-definition>
C15702
Therapeutic or Preventive Procedure
The determination of the amount of apolipoprotein H present in a sample.
Apolipoprotein H Measurement
Apolipoprotein H Measurement
C82003
owl:Class
Apolipoprotein H Measurement
Apolipoprotein H Measurement
Protein or Enzyme Type Measurement
Organ Culture
Organ Culture
owl:Class
Organ Culture
Tissue Culture
Laboratory Procedure
Culturing, in vitro Vertebrate, Organ
C16941
C0029205
Organ Culture
The maintenance or growth of tissues, organ primordia, or the parts or whole of an organ in vitro in such a way as to allow differentiation or preservation of the architecture or function.
<def-source>MSH2001</def-source><def-definition>A technique for maintenance or growth of animal organs in vitro. It refers to three-dimensional cultures of undisaggregated tissue retaining some or all of the histological features of the tissue in vivo. (Freshney, Culture of Animal Cells, 3d ed, p1)</def-definition>
Culturing, in vitro Organ
Blood Screening
Diagnostic Procedure
CL003591
C15960
Blood Screening
Blood Screening
Blood Screening
owl:Class
Examination of the blood from a group of usually asymptomatic individuals to detect those with a high probability of having a given disease, typically by means of inexpensive diagnostic tests.
Disease Screening
CDISC SDTM Laboratory Test Terminology by Code
CL384369
Laboratory Procedure
Anti-Double Stranded DNA Measurement
C74913
The determination of the amount of anti-double stranded DNA present in a sample.
CDISC SDTM Laboratory Test Terminology by Name
DNA Analysis
Anti-Double Stranded DNA Measurement
CDISC
CDISC SEND Terminology
owl:Class
Clinical Data Interchange Standards Consortium Terminology
Anti-Double Stranded DNA Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the anti-double stranded DNA antibody in a biological specimen.</def-definition>
ADSDNA
Anti-Double Stranded DNA Measurement
CDISC SDTM Terminology
Anti-Double Stranded DNA
owl:Class
Sodium Measurement
Urine Sodium Measurement
Laboratory Procedure
Urine Sodium Measurement
C1256585
A quantitative measurement of the total amount of sodium present in a sample of urine.
Urine Sodium Measurement
C61045
Urine Sodium Measurement
Urine Chemistry Measurement
Treatment Study
<def-source>CDISC</def-source><def-definition>A type of study protocol designed to evaluate intervention(s) for treatment of disease, syndrome or condition.</def-definition>
owl:Class
Research Activity
Treatment Study
CDISC SDTM Trial Indication Type Terminology
Clinical Data Interchange Standards Consortium Terminology
Treatment Study
TREATMENT
CDISC SDTM Terminology
Trial Indication Type
CL354847
A type of study protocol designed to evaluate intervention(s) for disease treatment.
C49656
CDISC
Treatment Study
owl:Class
Nutritional Biochemistry
Nutritional Biochemistry
CL000608
Nutritional Biochemistry
Nutritional Study
The study of the biochemistry of foods and vitamins as they affect the body
C15827
Nutritional Biochemistry
Research Activity
Community Trial
CL323470
Research Activity
owl:Class
C39365
The Community Trial is a planned experiment that involves administering an exposure within a community in order to elucidate its impact on the incidence of a specific disease in that community. The community trial is a choice when exposure cannot be prevented among control group.
Community Trial
Community Trial
Community Trial
Research Activity
C15584
Quality-of-Life Assessment
owl:Class
Quality of Life Assessment
Quality-of-Life Assessment
Quality-of-Life Assessment
CL030827
Quality-of-Life Assessment
Health Care Activity
Supportive Care
C75341
The determination of the amount of any drug that depresses the central nervous system (CNS) present in a sample.
CNS Depressant Drug Measurement
CNS Affecting Drug Measurement
Laboratory Procedure
CNS Depressant Drug Measurement
owl:Class
CNS Depressant Drug Measurement
CNS Depressant Drug Measurement
CL384617
The determination of the amount of interleukin 25 present in a sample.
Cytokine Measurement
Laboratory Procedure
CL384303
CDISC SDTM Laboratory Test Terminology by Name
Interleukin 25 Measurement
Interleukin 25 Measurement
Clinical Data Interchange Standards Consortium Terminology
Interleukin 25 Measurement
CDISC SDTM Terminology
CDISC SEND Terminology
Interleukin 25 Measurement
CDISC SDTM Laboratory Test Terminology by Code
owl:Class
C74822
INTLK25
Interleukin 25
<def-definition>A measurement of the interleukin 25 in a biological specimen.</def-definition><def-source>CDISC</def-source>
CL369068
Bioconductor caAffy Player Out Probe Summary Method
Bioconductor caAffy Player Out Probe Summary Method
Probe Summary Method
C64226
Bioconductor caAffy Player Out Probe Summary Method
Activity
Player Out
Bioconductor caAffy Player Out Probe Summary Method
Summarizes probe sets using the 'player out' statistical algorithm. Defined in the documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html.
Player Out Probe Summary Method
owl:Class
Therapeutic or Preventive Procedure
Physical Medicine Procedure
Physical Therapy
Physiatric Procedure
PT
Physical Therapy
<def-source>MSH2001</def-source><def-definition>The restoration of function and the prevention of disability following disease or injury with the use of light, heat, cold, water, electricity, ultrasound, and exercise.</def-definition>
Physical Therapeutics
C0949766
Physical Therapy Procedure
C15302
<def-source>NCI-GLOSS</def-source><def-definition>The use of exercises and physical activities to help condition muscles and restore strength and movement. For example, physical therapy can be used to restore arm and shoulder movement and build back strength after breast cancer surgery.</def-definition>
Supportive Care
Physical Therapy
Physiotherapy
Physiotherapy Procedure
Physical Therapy
owl:Class
physical therapy
owl:Class
Bone marrow ablation followed by replacement of stem cells in the circulating blood to help the bone marrow recover and continue producing healthy blood cells.
Bone Marrow Ablation with Stem Cell Support
C15587
Bone Marrow Ablation
Bone Marrow Ablation with Stem Cell Support
CL030842
Therapeutic or Preventive Procedure
Bone Marrow Ablation with Stem Cell Support
Bone Marrow Ablation with Stem Cell Support
Microarray Analysis
DNA Microarray Analysis
C0600596
DNA Microarray Analysis
Laboratory Procedure
DNA Microarray Analysis
owl:Class
Gene Microarray
DNA Microarray Analysis
C25922
DNA Microarray
This term describes an experiment in which probes representing genes that one wants to study are affixed to a substrate (e.g., a glass slide) and then exposed to target molecules (sometimes referred to as the sample). The level of hybridization between a specific probe and a target (typically indicated through fluorescence and measured through image analysis) indicates the level of the gene corresponding to that probe in a test solution.
CDISC SEND Terminology
CL384391
HIV-2 Antibody Measurement
HIV-2 Antibody Measurement
HIV-2 Antibody Measurement
HIV2AB
HIV-2 Antibody
<def-source>CDISC</def-source><def-definition>A measurement of the antibody reaction of a biological specimen to the HIV-2 virus.</def-definition>
Clinical Data Interchange Standards Consortium Terminology
The determination of the antibody reaction of a sample to the HIV-2 virus.
owl:Class
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
HIV Measurement
HIV-2 Antibody Measurement
C74715
Laboratory Procedure
CDISC
Postoperative care of surgery patients.
Surgical Management
Surgical Management
Surgical Management
Surgical Management
Supportive Care
C16080
owl:Class
Therapeutic or Preventive Procedure
CL008504
The determination of the number of unclassified casts present in a urine sample.
C74776
<def-source>CDISC</def-source><def-definition>A measurement of the unclassifiable casts present in a urine specimen.</def-definition>
CL384430
Clinical Data Interchange Standards Consortium Terminology
owl:Class
Unclassified Cast Measurement
CSUNCLA
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Laboratory Test Terminology by Code
Unclassified Casts
CDISC SDTM Terminology
Unclassified Cast Measurement
Unclassified Cast Measurement
Laboratory Procedure
Urine Sediment Analysis Measurement
Unclassified Cast Measurement
CDISC
owl:Class
Indium Scan
Diagnostic Procedure
C38089
An imaging procedure using Indium-111 labeled leukocytes to detect sites of infection and/or inflammation.
Indium Scan
Indium Scan
Radionuclide Imaging
Indium Scan
CL322434
CDISC SEND Terminology
The determination of the amount of noradrenaline hormone present in a sample.
CDISC SDTM Terminology
Clinical Data Interchange Standards Consortium Terminology
Noradrenaline Measurement
Noradrenaline Measurement
Noradrenaline Measurement
<def-definition>A measurement of the norepinephrine hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
Norepinephrine
owl:Class
Hormone Measurement
Noradrenaline Measurement
Noradrenaline
CDISC SDTM Laboratory Test Terminology by Code
Laboratory Procedure
NOREPIN
C0202145
C74868
CDISC SDTM Laboratory Test Terminology by Name
The act or an instance of returning from one location or situation to the previous one. Concept also refers to a return telephone or radio call, particularly when a survey is conducted; and to a recall of a recently sold product (e.g. pharmaceutical) by the manufacturer.
Action
Conceptual Entity
owl:Class
C37922
Callback
C1516151
Callback
Callback
Callback
Clinical Data Interchange Standards Consortium Terminology
Monoblasts
CDISC SDTM Terminology
The determination of the number of monoblast cells present in a sample.
Laboratory Procedure
<def-source>CDISC</def-source><def-definition>A measurement of the monoblast cells per unit of a biological specimen.</def-definition>
Monoblast Count
MONOBL
C74631
CDISC SDTM Laboratory Test Terminology by Name
Blast Count
Monoblast Count
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Code
CL104324
Monoblast Count
CDISC
owl:Class
Monoblast Count
Put an end to a state or an activity.
Stop
Activity
Instruction Imperative
Stop
Stop
Cease
Finish
owl:Class
Event
C65125
C1706059
Stop
Mucin-2 Staining Method
Mucin 2 Staining Method
owl:Class
C23033
Mucin-2 Staining Method
Mucin-2 Staining Method
An immunohistochemical technique used to detect the gene product of the MUC2 gene, using monoclonal antibodies directed against mucin-2 glycoprotein.
Mucin 2
Laboratory Procedure
MUC2
CL100948
Special Histology Staining Method
Mucin-2 Staining Method
Mucin 2 Staining Method
CL378385
Bronchial Artery Infusion Procedure
C72143
Infusion Procedure
owl:Class
Bronchial Artery Infusion Procedure
Bronchial Artery Infusion Procedure
Bronchial Artery Infusion Procedure
Therapeutic or Preventive Procedure
owl:Class
This initiative is intended to advance the state-of-the-art in digital mammography displays and workstation design to facilitate clinical acceptance and implementation of digital mammography for improved breast cancer diagnosis. This PA will solicit research and development in three critical areas in digital mammography: 1) Softcopy Display Hardware; 2) Workstation Software and Design; and 3) Image Perception.
CL003287
Research Activity
Development and Testing of Digital Mammography Displays and Workstations
Development and Testing of Digital Mammography Displays and Workstations
C15948
Technology Development
Development and Testing of Digital Mammography Displays and Workstations
Development and Testing of Digital Mammography Displays and Workstations
C0201215
Bacterial Typing Procedure
owl:Class
A procedure for identifying types and strains of bacteria. The most frequently used typing systems are bacteriophage typing, serotyping, bacteriocin typing, and biotyping.
Bacterial Typing Procedure
Laboratory Procedure
Bacterial Typing Procedure
C51955
Culture Procedure
Bacterial Typing Procedure
Atrial Ablation
A invasive therapeutic procedure in which a catheter is threaded through veins into the cardiac atria to destroy the tissue that is the source of an arrhythmia.
Cardiac Therapeutic Procedure
Ablation Therapy
Atrial Ablation
owl:Class
Atrial Ablation
Atrial Ablation
C80432
Therapeutic or Preventive Procedure
C62683
Breast Imaging Study
Breast Imaging Study
Breast Imaging Study
Image Study
owl:Class
Breast Imaging Study
CL035539
Diagnostic Procedure
The concept encompasses various treatment modalities including active and passive immunization, treatment with immunopotentiators, immunosuppressants and nonspecific systemic immunostimulators and adjuvants, desensitization to any allergens, bone marrow transplantation, thymus implantation.
Immunotherapy
<def-source>NCI-GLOSS</def-source><def-definition>(IM-yoo-no-THER-a-pee) Treatment to stimulate or restore the ability of the immune system to fight infections and other diseases. Also used to lessen side effects that may be caused by some cancer treatments.</def-definition>
Immunotherapy
C15262
Immunologically Directed Therapy
owl:Class
Therapeutic or Preventive Procedure
immunotherapy
Therapy designed to induce changes in a patient's immune status in order to treat disease.
C0021083
Immunotherapy
Biological Therapy
Immunotherapy
Research Activity
owl:Class
The Selenium and Vitamin E Efficacy Trial (SELECT) will provide more definitive evidence of the efficacy of these drugs in preventing prostate cancer. (from The NCI Strategic Plan to Reduce Health Disparities)
C16179
Selenium and Vitamin E Efficacy Trial
CL014993
Selenium and Vitamin E Efficacy Trial
SELECT
Selenium and Vitamin E Efficacy Trial
Selenium and Vitamin E Efficacy Trial
Selenium and Vitamin E Cancer Prevention Trial
Prostate Cancer Prevention Trial
owl:Class
<def-source>CDISC</def-source><def-definition>A count of the CD8 T cells per unit of a biological specimen.</def-definition>
CDISC SEND Terminology
C74609
CDISC SDTM Laboratory Test Terminology by Name
CD8 Expressing T Cell Count
CL384724
CD8 Expressing T Cell Count
CDISC SDTM Laboratory Test Terminology by Code
CD8
Laboratory Procedure
CD8 Expressing T Cell Count
Lymphocyte Count
CDISC
The determination of the number of CD8 expressing T cells present in a sample.
Clinical Data Interchange Standards Consortium Terminology
CD8 Expressing T Cell Count
CDISC SDTM Terminology
Lead Extraction
The removal of one or more lead wires from the heart in a patient with pacemaker or implantable defibrillator.
Therapeutic or Preventive Procedure
C80437
Lead Extraction
Cardiac Therapeutic Procedure
Lead Extraction
owl:Class
Lead Extraction
The transmission or conveying of something through a medium or passage, especially the transmission of heat or electricity or sound.
Conduction
Conduction
Conduction
owl:Class
C61530
C0457405
Conduction
Activity
Action
C15860
Nutrition, Trace Elements
Studies of the role of the trace element mercury, obtained through diet, on general health
owl:Class
Trace Element Nutrition, Mercury
Trace Element Nutrition, Mercury
Trace Element Nutrition, Mercury
Trace Element Nutrition, Mercury
Research Activity
CL000999
<def-source>NCI-GLOSS</def-source><def-definition>Bathing an organ or tissue with a fluid. In regional perfusion, a specific area of the body (usually an arm or a leg) receives high doses of anticancer drugs through a blood vessel. Such a procedure is performed to treat cancer that has not spread.</def-definition>
C15295
C0031001
Perfusion
Therapeutic or Preventive Procedure
perfusion
Perfusion
The process of flooding fluid through the artery to saturate the surrounding tissue. In regional perfusion, a specific area of the body (usually an arm or a leg) is targeted and high doses of anticancer drugs are flooded through the artery to reach the surrounding tissue and kill as many cancer cells as possible. Such a procedure is performed in cases where the cancer is not thought to have spread past a localized area.
owl:Class
Regional Chemotherapy
Perfusion
Perfusion
C16209
Use of a device, marker, or other means for the purpose of detecting the presence of a tumor early in its development.
Early Detection
Early Detection
owl:Class
Diagnostic Procedure
Early Detection
CL024896
Detection
Early Detection
Exercise Thallium
Thallium Myocardial Perfusion Imaging Stress Test
Thallium Myocardial Perfusion Imaging Stress Test
Stress Thallium Test
Nuclear Stress Test
Thallium Myocardial Perfusion Imaging Stress Test
C0743636
owl:Class
A nuclear imaging procedure, using the radionuclide Thallium, that shows whether the heart muscle is receiving adequate blood supply under stress and/or rest conditions.
Diagnostic Procedure
Thallium Myocardial Perfusion Imaging Stress Test
C38058
Diagnostic Imaging
E-Cadherin Staining Method
Ecadherin Staining Method
E-Cadherin Staining Method
E-Cadherin Staining Method
Special Histology Staining Method
owl:Class
E-Cadherin Staining Method
Laboratory Procedure
An immunohistochemical technique to detect E-Cadherin, a transmembrane glycoprotein that is localized in the adherens junctions of epithelial cells, using antibody to E-Cadherin . The loss of expression or function of E-Cadherin appears to be an important step in tumorigenic progression.
C23023
Ecadherin Staining Method
CL319117
ECAD
Ecadherin
C62713
Oncolytic Virus Therapy
owl:Class
Oncolytic Virus Therapy
Therapeutic or Preventive Procedure
Oncolytic Virus Therapy
Oncolytic Virus Therapy
Biological Therapy
C1563738
Hormone Measurement
CL384282
Gonadotropin Releasing Hormone Measurement
Luteinising Hormone Releasing Hormone
CDISC SDTM Terminology
Gonadotropin Releasing Hormone Measurement
C74860
Laboratory Procedure
Gonadotropin Releasing Hormone Measurement
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Code
Gonadotropin Releasing Hormone
owl:Class
CDISC SDTM Laboratory Test Terminology by Name
The determination of the amount of gonadotropin releasing hormone present in a sample.
<def-definition>A measurement of the gonadotropin releasing hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
GNRH
Gonadotropin Releasing Hormone Measurement
Clinical Data Interchange Standards Consortium Terminology
R-Banding
Chromosome Banding
R-Banding
R-Banding
CL004374
R-Banding
Using acridine orange, this technique produces a chromosomal staining pattern which is the reverse of G-banding.
owl:Class
C19479
Laboratory Procedure
Patellectomy
Patellectomy
CL354145
Surgical removal of part or all of the patella.
C51641
owl:Class
Orthopedic Surgical Procedure
Patellectomy
Patellectomy
Therapeutic or Preventive Procedure
Procedure_Has_Excised_Anatomy only Patella
Stenting
Therapeutic or Preventive Procedure
C62741
Biliary Stenting
Biliary Stenting
CL365522
Biliary Stenting
owl:Class
Surgical placement of a plastic or metal tube into the bile duct to treat bile duct stricture.
Biliary Stenting
Biliary Tract Surgery
Reservation
Reserve
Activity
Reservation
C71729
owl:Class
Reservation
Reservation
CL378333
Action
The act of keeping back or setting aside for some future occasion.
Sodium Dodecylsulfate-Polyacrylamide Gel Electrophoresis
Sodium Dodecylsulfate-Polyacrylamide Gel Electrophoresis
C18150
Sodium Dodecylsulfate-Polyacrylamide Gel Electrophoresis
Sodium dodecyl sulfate (SDS) polyacrylamide gel electrophoresis is a procedure for estimating molecular weights of polypeptides, and uses SDS, a detergent that dissociates and unfolds oligomeric proteins into its subunits. The SDS binds to the polypeptides to form complexes with fairly constant charge to mass ratios. The electrophoretic migration rate through a gel is therefore determined only by the size of the complexes.
Sodium Dodecylsulfate-Polyacrylamide Gel Electrophoresis
Laboratory Procedure
Polyacrylamide Gel Electrophoresis
owl:Class
SDS-PAGE
Molecular Biology Research Technique
C0600209
Mixed Category Laboratory Procedure
owl:Class
A laboratory procedure that is performed in more than one of these laboratory specializations: anatomic pathology, clinical pathology, or molecular pathology.
C74957
Laboratory Procedure
Laboratory Procedure
Mixed Category Laboratory Procedure
Mixed Category Laboratory Procedure
Mixed Category Laboratory Procedure
CL384517
owl:Class
Urine Creatinine Measurement
A quantitative measurement of the total amount of creatinine present in a sample of urine.
Laboratory Procedure
Urine Chemistry Measurement
Urine Creatinine Measurement
Urine Creatinine Measurement
C61048
C1318439
Urine Creatinine Measurement
Methamphetamine Measurement
Amphetamine Drug Class Measurement
Methamphetamine Measurement
Methamphetamine Measurement
The determination of the amount of methamphetamine present in a sample.
Methamphetamine Measurement
owl:Class
C0202419
Laboratory Procedure
C75348
C53241
owl:Class
Quantitative Concept
Analysis of Variance
Parametric Regression Method
Analysis of Variance
Analysis of Variance
C0002780
Analysis of Variance
ANOVA
A statistical technique which helps in making inference whether three or more samples might come from populations having the same mean; specifically, whether the differences among the samples might be caused by chance variation.
owl:Class
C0344093
Therapeutic Procedure
Interventional Radiology Procedure
Interventional Radiology Procedure
Interventional Radiology Procedure
Therapeutic or Preventive Procedure
Interventional Radiology Procedure
C63334
CD4 T Cell to CD8 T Cell Ratio Measurement
CDISC SDTM Terminology
CD4 T Cell to CD8 T Cell Ratio Measurement
C74637
CDISC SDTM Laboratory Test Terminology by Name
The determination of the ratio of CD4 T cells compared to CD8 T cells present in a sample. The measurement may be expressed as a ratio or percentage.
owl:Class
<def-source>CDISC</def-source><def-definition>A relative measurement (ratio or percentage) of CD4 T cells to the CD8 T cells in a biological specimen.</def-definition>
CD4 T Cell to CD8 T Cell Ratio Measurement
CDISC SDTM Laboratory Test Terminology by Code
CDISC SEND Terminology
CDISC
CD4CD8
Blood Cell Count Ratio Measurement
CD4 T Cell to CD8 T Cell Ratio Measurement
Clinical Data Interchange Standards Consortium Terminology
CL384270
Laboratory Procedure
CD4/CD8
Other Prior Therapy
Other Prior Therapy
Other Prior Therapy
Prior Therapy
CL014628
Clinical Attribute
owl:Class
Other Prior Therapy
C16172
CL083039
Research Activity
Organism Modification
Knock-in
Knock-in
Knock-in
C22492
Replacement of a gene by an altered version of the same gene using homologous recombination resulting in a gain of function. One example of a knock-in is deletion of a coding sequence of a gene in a mouse and then replacing it with human coding sequences.
Mouse Model Model
Knock-in
Knock-in
owl:Class
Deoxypyridinoline to Creatinine Ratio Measurement
CDISC SEND Terminology
Deoxypyridinoline to Creatinine Ratio Measurement
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Name
<def-definition>A relative measurement (ratio or percentage) of the deoxypyridinoline to creatinine in a biological specimen.</def-definition><def-source>CDISC</def-source>
C79444
Deoxypyridinoline to Creatinine Ratio Measurement
Laboratory Procedure
The determination of the ratio of deoxypyridinoline compared to creatinine present in a sample. The measurement may be expressed as a ratio or percentage.
CDISC SDTM Terminology
DPDCREAT
Deoxypyridinoline to Creatinine Ratio Measurement
owl:Class
Urine Protein Measurement
CDISC SDTM Laboratory Test Terminology by Code
Deoxypyridinoline/Creatinine
Agarose Gel Fractionation
Agarose Gel Electrophoresis
Agarose Gel Electrophoresis
A type of electrophoresis that uses a matrix of highly purified agar to separate large molecules.
Fractionation, Agarose Gel
Gel Electrophoresis
C16537
Agarose Gel Electrophoresis
Laboratory Procedure
C0013856
Agarose Gel Electrophoresis
owl:Class
Molecular Biology Research Technique
owl:Class
Unit Dose
Unit Dose
Conceptual Entity
Unit Dose
Dose
Unit Dose
C0869039
C65135
Kyphoplasty
Orthopedic Surgical Procedure
owl:Class
C1455863
Therapeutic or Preventive Procedure
C62742
Procedure_Has_Target_Anatomy only 'Vertebral Column'
Kyphoplasty
Kyphoplasty
Kyphoplasty
A procedure with the intent of expanding a collapsed vertebra. A surgical instrument is introduced into the spine with a balloon that is inflated to expand the bone. Once this instrument is withdrawn, the space created is then filled with bone cement mixture.
Homeopathy Therapy
Therapeutic or Preventive Procedure
Homeopathic Remedy
owl:Class
Homeopathic
Homeopathy Therapy
Homeopathy Therapy
Homeopathy
Alternative Medical Procedure
Biomedical Occupation or Discipline
Homeopathy Therapy
homeopathic remedies
C15718
A method of treating disease with small amounts of remedies that, in large amounts in healthy people, produce symptoms similar to those being treated. Homeopathy seeks to stimulate the body's defense mechanisms and processes so as to prevent or treat illness.
<def-source>NCI-GLOSS</def-source><def-definition>Small doses of medicines, herbs, or both that are believed to stimulate the immune system.</def-definition>
C0684199
Procedure_May_Have_Completely_Excised_Anatomy some Gallbladder
Abdominal Surgical Procedure
Procedure_Has_Partially_Excised_Anatomy only Duodenum
Surgical removal of part of the pancreas, duodenum, and distal part of the bile duct. Sometimes, the lower portion of the stomach and the gallbladder are also removed. This procedure is performed for pancreatic, ampullary, duodenal and distal bile duct cancers.
Therapeutic or Preventive Procedure
Procedure_Has_Completely_Excised_Anatomy only 'Ampulla of Vater'
Procedure_Has_Partially_Excised_Anatomy only 'Bile Duct'
Whipple Procedure
Procedure_May_Have_Partially_Excised_Anatomy some Stomach
Whipple Procedure
Procedure_Has_Partially_Excised_Anatomy only Pancreas
Whipple Procedure
owl:Class
Whipple procedure
C15356
Digestive System Surgery
Whipple Procedure
C0085162
Isoelectric Focusing
Fractionation, Isoelectric Focusing
A type of gel electrophoresis in which charged molecules travel through a pH gradient. The molecules will come to stop at the point where the net charge on the molecule is equal to that of the surrounding gel.
Isoelectric Focusing
C0022169
Isoelectric Focusing
Molecular Biology Research Technique
<def-source>MSH2001</def-source><def-definition>Electrophoresis in which a pH gradient is established in a gel medium and proteins migrate until they reach the site (or focus) at which the pH is equal to their isoelectric point.</def-definition>
Isoelectric Focusing
C16758
Laboratory Procedure
owl:Class
Gel Electrophoresis
C63918
owl:Class
Cluster Analysis
Research Activity
Cluster Analysis
Cluster Analysis
Clustering
C0009085
Statistical Technique
Clustering Analysis
Cluster Analysis
Methods for grouping objects into subsets such that those within each cluster are more closely related to one another than objects assigned to different clusters.
Management
Performing or possessing executive duties; acting as a supervisor or manager.
Administration
Administration, Management
Administration, Management
Administrative Activity
C0001554
C48905
Activity
owl:Class
Administration, Management
Administration, Management
A quantitative measurement of the amount of lactate dehydrogenase present in a sample of serum.
C61026
Serum Lactate Dehydrogenase Measurement
owl:Class
Serum Lactate Dehydrogenase Measurement
Serum Lactate Dehydrogenase Measurement
Laboratory Procedure
C1278052
Serum Lactate Dehydrogenase Measurement
Serum Chemistry Measurement
C0598304
owl:Class
A laboratory method in which the tissue from a histology slide is dissected under a microscope to procure specific cells or cell populations.
Microdissection
Microtechnique
Microdissection
Histological Procedure
Microdissection
Microdissection
C18124
Laboratory Procedure
Instruction Imperative
C48167
Activity
The act of moving something from one location to another.
Delivered
Transfer Technique
Conceptual Entity
Transfer
Transport
CL343303
Action
Transfer
owl:Class
Delivery
Deliver
CL106613
Transfer
Transfer
The act of conveying or transporting from one place to another.
C38083
DLCO
A measurement of carbon monoxide (CO) transfer from inspired gas to pulmonary capillary blood. During the test, the subject inspires a gas containing CO and one or more tracer gases to allow determination of the gas exchanging capability of the lungs.
Carbon Monoxide Diffusing Capability Test
Diagnostic Procedure
CL322431
owl:Class
Pulmonary Function Test/Carbon Monoxide Diffusing Capability
Carbon Monoxide Diffusing Capability Test
Carbon Monoxide Diffusing Capability Test
PFT/DLCO
Diffusion Capacity of the Lung for Carbon Monoxide
Carbon Monoxide Diffusing Capability Test
Pulmonary Function Test
Behavioral Research
owl:Class
Behavioral Mechanisms
CL003984
Research Activity
Studies that develop and test specific interventions aimed at changing negative health behaviors.
Behavioral Mechanisms
Behavioral Mechanisms
C15996
Mechanisms of Behavior and Behavior Change
Behavioral Mechanisms
Laboratory Procedure
Myeloperoxidase Measurement
The determination of the amount of myeloperoxidase present in a sample.
owl:Class
Myeloperoxidase Measurement
Protein or Enzyme Type Measurement
Myeloperoxidase Measurement
Myeloperoxidase Measurement
C80198
Whey Acidic Protein Staining Method
Whey Acidic Protein
WAP
Whey Acidic Protein Staining Method
CL100946
Laboratory Procedure
Whey Acidic Protein Staining Method
Whey Acidic Protein Staining Method
Special Histology Staining Method
An immunohistochemical technique to identify whey acidic protein (WAP), a major whey protein secreted in rodent's milk. WAP promoter has been used for targeting heterologous genes to the mammary gland. The technique is used in diagnostic histopathology to identify breast cancer.
C23030
Whey Acidic Protein Staining Method
owl:Class
Type I Collagen N-Telopeptide Measurement
Type I Collagen N-Telopeptide Measurement
C82039
Protein or Enzyme Type Measurement
owl:Class
Type I Collagen N-Telopeptide Measurement
The determination of the amount of the type I collagen N-telopeptide present in a sample.
Type I Collagen N-Telopeptide Measurement
C64927
owl:Class
Swallow
Activity
Swallow
Instruction Imperative
Swallow
Swallow
CL370601
Laboratory Procedure
A technique for quantitation of cell DNA content.
C20098
CL017657
DNA Image Cytometry
DNA Image Cytometry
Diagnostic Procedure
DNA Image Cytometry
DNA ICM
DNA Image Cytometry
owl:Class
Flow Cytometry
<def-source>NCI-GLOSS</def-source><def-definition>(UL-tra-son-OG-ra-fee) A procedure in which sound waves (called ultrasound) are bounced off tissues and the echoes produce a picture (sonogram).</def-definition>
US
A technique in which high-frequency sound waves are bounced off internal organs and the echo pattern is converted into a 2 dimensional picture of the structures beneath the transducer.
C0041618
Ultrasound
Ultrasound Imaging
Ultrasound, Medical
Diagnostic Procedure
Newborn Screening
Ultrasound Imaging
Diagnostic Imaging
ultrasonography
owl:Class
Medical Imaging, Ultrasound
Ultrasonography
Ultrasound Imaging
C17230
Ultrasound Imaging
ultrasound test
Ultrasound Test
Experiment
Experiment
owl:Class
Research Activity
C42790
Experiment
A set of actions and observations, performed to verify or falsify a hypothesis or research a causal relationship between phenomena.
Research Activity
C0681814
Experiment
Lactic Acid Measurement
CDISC SDTM Laboratory Test Terminology by Code
Lactic Acid Measurement
Clinical Data Interchange Standards Consortium Terminology
C79450
CDISC SDTM Laboratory Test Terminology by Name
Lactic Acid Measurement
CDISC SEND Terminology
Lactate
<def-definition>A measurement of the lactic acid in a biological specimen</def-definition><def-source>CDISC</def-source>
Lactic Acid Measurement
2-hydroxypropanoic acid
CDISC SDTM Terminology
owl:Class
Laboratory Procedure
Chemistry Test
LACTICAC
Lactic Acid
The determination of the amount of lactic acid present in a sample.
Hematopoietic Stem Cell Research
Hematopoietic Stem Cell Research
Hematopoietic Stem Cell Research
C16201
owl:Class
CL024202
Biomedical Occupation or Discipline
Stem Cell Research
Hematopoietic Stem Cell Research
Laboratory Procedure
CDISC SDTM Terminology
Potassium to Creatinine Ratio Measurement
C79462
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
Potassium to Creatinine Ratio Measurement
Potassium/Creatinine
KCREAT
Potassium to Creatinine Ratio Measurement
owl:Class
Urine Protein Measurement
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Code
<def-definition>A relative measurement (ratio or percentage) of the potassium to creatinine in a biological specimen.</def-definition><def-source>CDISC</def-source>
Potassium to Creatinine Ratio Measurement
The determination of the ratio of potassium compared to creatinine present in a sample. The measurement may be expressed as a ratio or percentage.
Behavioral, Psychological or Informational Intervention
C62739
CL365581
Exercise Intervention
Therapeutic or Preventive Procedure
Preventive Intervention
owl:Class
Exercise Intervention
Exercise Intervention
Exercise Intervention
Activity
C0009830
owl:Class
Action
The using or using up of goods and services, especially the rate at which they are used.
Consumption of Goods
Consumption of Goods
Consumption of Goods
Consumption
Consumption of Goods
C66716
Clinical Data Interchange Standards Consortium Terminology
PROGEST
Progesterone Measurement
Progesterone Measurement
Progesterone
CDISC SDTM Laboratory Test Terminology by Code
Laboratory Procedure
C74791
CDISC
CDISC SDTM Laboratory Test Terminology by Name
The determination of the amount of progesterone present in a sample.
CDISC SEND Terminology
<def-source>CDISC</def-source><def-definition>A measurement of the progesterone hormone in a biological specimen.</def-definition>
CDISC SDTM Terminology
C0373705
Progesterone Measurement
Hormone Measurement
owl:Class
Progesterone Measurement
C15945
Small Animal Imaging Resource Programs
owl:Class
Small Animal Imaging Resource Programs (SAIRPs)
Small Animal Imaging Resource Programs
A program to improve access to researchers testing new approaches to diagnosis, treatment and prevention in animal models of cancer. Focus will be on functional, quantitative imaging. (Bypass Budget)
CL003283
Small Animal Imaging Resource Programs
Diagnostic Imaging Program
Research Activity
Small Animal Imaging Resource Programs
SAIRP
Surveillance projects which focus on issues of cancer
Cancer Research
Research Activity
owl:Class
Cancer Surveillance Project
Cancer Surveillance Project
Cancer Surveillance Project
C16068
Cancer Surveillance Project
CL008196
Serum Chloride Measurement
C1317978
Serum Chloride Measurement
Serum Chemistry Measurement
C61021
Chloride Measurement
Serum Chloride Measurement
Laboratory Procedure
Serum Chloride Measurement
A quantitative measurement of the amount of chloride present in a sample of serum.
owl:Class
CL375865
Activity
Regulatory Assessment
Regulatory Assessment
Regulatory Assessment
C70887
owl:Class
Administrative Activity
Regulatory Assessment
A regulatory action or inaction undertaken by the regulatory authority as a result of a submission analysis and evaluation.
Receive
C25639
CL052596
Receive
Action
Qualitative Concept
Received
Receive
To take, accept, or got something offered.
owl:Class
Receive
Health Service Region Level Statistic
Health Service Region Level Statistic
Health Service Region Level Statistic
CL355730
Geographic Area Level Statistic
owl:Class
Health Service Region Level Statistic
Quantitative Concept
C53189
Biochemistry and Pharmacology Cancer Activity
Biochemistry and Pharmacology Cancer Activity
CL003322
Biochemistry and Pharmacology Cancer Activity
owl:Class
C19267
Research Activity
Biochemistry and Pharmacology Cancer Activity
Cancer Research
Preclinical studies designed to improve cancer treatment, with an emphasis on the discovery of new drugs and treatment strategies, selective targeting, development of new preclinical models, and understanding, preventing, and overcoming drug resistance.
Biochemistry and Pharmacology
CDISC
Clinical Study by Product, Procedure, or Method Tested
CL353683
Trial Type
Clinical Data Interchange Standards Consortium Terminology
owl:Class
<def-source>CDISC</def-source><def-definition>The type of clinical trial performed e.g. efficacy, safety. (NCI)</def-definition>
CDISC SDTM Trial Summary Parameter Terminology by Code
Study Design
CDISC SDTM Terminology
Trial Type
CDISC SDTM Trial Summary Parameter Terminology by Name
Trial Type
The type of clinical trial performed e.g. efficacy, safety.
TTYPE
Trial Type
C49660
Research Activity
Quantile
Statistical Technique
C48920
Qualitative Concept
owl:Class
Quantile
Quantile
Division of a distribution into equal, ordered subgroups; a set of 'cut points' that divide a sample of data into groups containing (as far as possible) equal numbers of observations.
Quantile
CL343848
Health Care Activity
Therapy Evaluation
owl:Class
CL102419
Clinical Testing
Therapy Evaluation
C15857
Determining the efficacy of a particular therapy or treatment
Therapy Evaluation
Therapy Evaluation
CL365545
C63327
Clonality Analysis
Laboratory Procedure
Clonality Analysis
Molecular Analysis
Clonality Analysis
Clonality Analysis
owl:Class
Laminectomy
Laminectomy
The excision of the vertebral posterior arch.
Procedure_Has_Excised_Anatomy only 'Vertebral Bone'
Head and Neck Surgery
C0022983
owl:Class
Therapeutic or Preventive Procedure
Laminectomy
Laminectomy
C21061
C28031
owl:Class
Mutate
CL054517
Mutate
Mutate
Mutate
Genetic Function
mutate
Action
<def-source>NCI-GLOSS</def-source><def-definition>To change the genetic material of a cell. The changes (mutations) can be harmful, beneficial, or have no effect.</def-definition>
To undergo or cause genetic mutation.
RNA Analysis
RNA Analysis
Molecular biology procedures, including Northern Blot, Differential display, RT-PCR, and RNase protection for qualifying or quantifying RNA. (NCI/OSP)
RNA Analysis
Molecular Analysis
C18473
Laboratory Procedure
C0872262
owl:Class
RNA Analysis
<def-source>MSH2001</def-source><def-definition>In information retrieval, machine-sensing or identification of visible patterns (shapes, forms, and configurations). (Harrod's Librarians' Glossary, 7th ed)</def-definition>
Pattern Recognition/Display/Analysis
A branch of artificial intelligence concerned with the identification of visual or audio patterns by computers.For the computer to recognize the patterns, the patterns must be converted into digital signals and compared with patterns already stored in memory.Some uses of this technology are in character recognition, voice recognition, handwriting recognition, and robotics. (High-Tech Dictionary)
Computational Technique
Mental Process
Pattern Recognition
C1448473
Pattern Recognition
owl:Class
C16961
Pattern Recognition
Pattern Recognition
C40346
Laboratory Procedure
Culture Setup
Culture Setup
Culture Setup
Culture Setup
Culture Procedure
owl:Class
CL324330
The preparation work required for doing cell or tissue culture. This includes preparation of the medium and of the growth support material or growth chamber.
Matrix Metalloproteinase 7 Measurement
Laboratory Procedure
C80195
Matrix Metalloproteinase 7 Measurement
Matrix Metalloproteinase 7 Measurement
Protein or Enzyme Type Measurement
Matrix Metalloproteinase 7 Measurement
The determination of the amount of matrix metalloproteinase 7 present in a sample.
owl:Class
Therapeutic or Preventive Procedure
Therapeutic Procedure
owl:Class
Antineoplastic Drug/Agent Therapy
Antineoplastic Drug/Agent Therapy
C71593
Antineoplastic Drug/Agent Therapy
CL378288
Antineoplastic Drug/Agent Therapy
Research Activity
Cancer Control Research
owl:Class
Cancer Control Research
Cancer Control Research
CL003608
C15963
Cancer Research
Cancer Control Research
C1526986
C15683
owl:Class
epidural
<def-source>NCI-GLOSS</def-source><def-definition>Having to do with the space between the wall of the spinal canal and the covering of the spinal cord. An epidural injection is given into this space.</def-definition>
Epidural Chemotherapy
Epidural Chemotherapy
Epidural Chemotherapy
Intrathecal Chemotherapy
Therapeutic or Preventive Procedure
Epidural Chemotherapy
owl:Class
CL354652
Immunohistochemical Test
Immunohistochemical Test
Laboratory Procedure
Immunohistochemical Test
Diagnostic Procedure
Immunohistochemical Test
C51944
A diagnostic test in which an antibody is used to link a cellular antigen specifically to a stain that can be seen with a microscope.
Histologic Test
C0681935
Quantitative Concept
Cross Validation
Statistical Technique
Cross Validation
Cross Validation
A statistical method of partitioning a sample of data into subsets such that the analysis is initially performed on a single subset, while the other subsets are retained for subsequent use in confirming and validating the initial analysis.
C78545
Cross Validation
owl:Class
To lay on a substance or preparation.
Apply
Instruction Imperative
C1632850
C64915
Apply
Apply
Activity
owl:Class
Apply
Both Safety and Lack of Expected Effectiveness
Both Safety and Lack of Expected Effectiveness
BOTH SAFETY AND LACK OF EXPECTED EFFECTIVENESS
owl:Class
C82452
Regulatory Assessment
Both Safety and Lack of Expected Effectiveness
Intellectual Product
Both Safety and Lack of Expected Effectiveness
Therapeutic or Preventive Procedure
Dietary Intervention
Behavioral Dietary Intervention
owl:Class
CL371404
Behavioral Intervention
Behavioral Dietary Intervention
The use of operant conditioning to alter a person's dietary choices and behaviors.
C67021
Behavioral Dietary Intervention
Behavioral Dietary Intervention
Action
C73624
Sharing
Use or hold jointly or in common.
CL383698
Share
owl:Class
Share
Activity
Share
Share
C0027646
staging
Staging
owl:Class
The process of defining at what point in the natural history of a malignant disease a patient is when a diagnosis is made.
Staging
C15608
Healthcare Activity
Staging
<def-source>NCI-GLOSS</def-source><def-definition>(STAY-jing) Performing exams and tests to learn the extent of the cancer within the body, especially whether the disease has spread from the original site to other parts of the body. It is important to know the stage of the disease in order to plan the best treatment.</def-definition>
Staging
Diagnostic Procedure
CL387557
Histamine Challenge Test
C78164
Histamine Challenge Test
Histamine Challenge Test
Pulmonary Function Test
Diagnostic Procedure
A test to determine if a patient has hyper-responsive airways.
Histamine Challenge Test
owl:Class
Vaccine Related Non-Development, AIDS
Vaccine Development
Vaccine Related Non-Development, AIDS
Vaccine Related Non-Development, AIDS
CL001073
Vaccine Related Non-Development, AIDS
Health Care Activity
C15871
owl:Class
C0009472
Community Health Service
Community Health Service
Diagnostic, therapeutic and preventive health service provided for individuals in the community.
C15213
Clinical Service
Community Health Service
Health Care Activity
Community Health Service
owl:Class
Activity
Attach
Cause to be firmly attached; stick or hold together and resist separation.
Fix
Immobile
Adhere
Fix
owl:Class
Fix
Attached
Fix
Action
C52253
C0443218
Adhered
Fixed
owl:Class
Suspension Culture
Suspension Culture
Cell Culture
C20217
Suspension Culture
Suspension Culture
Laboratory Procedure
CL026135
A type of culture in which cells, or aggregates of cells, multiply while suspended in liquid medium.
Three Dimensional Imaging
Three Dimensional Imaging
owl:Class
Three Dimensional Imaging
C18485
Technique to produce 3D images to provide the ability to visualize important structures in great detail. Traditionally CT and MRI scans produced static output on film. To produce 3D images, many scans are made, and then combined by computers to produce a 3D model, which can then be manipulated by the physician. 3D ultrasounds are produced using a somewhat similar technique.
Diagnostic Procedure
Medical Imaging, Three Dimensional
3-D Imaging
Three Dimensional Imaging
C0887832
Imaging Technique
A measure of how much blood the left ventricle of the heart pumps out with each contraction. With each beat, a normal heart ejects about one-half to two-thirds of the blood in its left chamber.
C0428772
Measurement of Left Ventricular Ejection Fraction
C37946
Cardiac Diagnostic Procedure
Measurement of Left Ventricular Ejection Fraction
Measurement of Left Ventricular Ejection Fraction
Measurement of Left Ventricular Ejection Fraction
owl:Class
Diagnostic Procedure
Nucleic Acid Hybridization
Molecular Analysis
C0028602
Laboratory procedure in which single stranded nucleic acids are allowed to interact so that complexes, or hybrids, are formed by molecules with sufficiently similar, complementary sequences. By this means the degree of sequence identity can be assessed and specific sequences detected. (From Biology-online)
Molecular Biology, Molecular Hybridization
Molecular Genetic Technique
Laboratory Procedure
Hybridization
Nucleic Acid Hybridization
Nucleic Acid Hybridization
Molecular Biology Research Technique
owl:Class
Nucleic Acid Hybridization
C16924
C65177
Single Linkage
Single Linkage Cluster Analysis
CL371310
Single Linkage Cluster Analysis
A clustering method in which the distance between two clusters is determined by the distance of the two closest objects (nearest neighbors) in the different clusters.
Single Linkage Clustering
Single Linkage Cluster Analysis
Nearest Neighbor
Single Linkage Cluster Analysis
Hierarchical Clustering
owl:Class
Research Activity
Action
CL383625
Phenomenon or Process
Encapsulation
Encapsulation
C73476
Activity
Encapsulation
The process or condition of being enclosed.
owl:Class
Encapsulation
CL364118
Blood Chemistry Measurement
Serum Chemistry Measurement
A quantitative measurement of a particular substance present in a sample of serum.
Serum Chemistry Measurement
owl:Class
Serum Chemistry Measurement
Laboratory Procedure
C61014
Serum Chemistry Measurement
Hirudotherapy
Therapeutic or Preventive Procedure
Leech Anticoagulant Therapy
Hirudotherapy
owl:Class
The use of leeches for medical therapy. From hirudin, the active principle in the salivary secretion of leeches that acts as a potent anticoagulant (bloodthinner). Hirudotherapy is mainly used in trauma and plastic and reconstructive surgery to salvage tissue flaps and skin grafts whose viability is threatened by venous congestion.
Therapeutic Procedure
C0262711
Hirudotherapy
Leech Therapy
C53582
Hirudotherapy
Postmenopausal Hormone Replacement Therapy
Postmenopausal Hormone Replacement Therapy
Postmenopausal Hormone Replacement Therapy
owl:Class
C15251
Therapeutic or Preventive Procedure
Postmenopausal Hormone Replacement Therapy
Hormone Replacement Therapy
C0019930
owl:Class
C51642
Procedure_Has_Partially_Excised_Anatomy only 'Bile Duct'
Removal of tissue from the bile duct for microscopic examination.
CL354436
Diagnostic Procedure
Biopsy of Bile Duct
Biopsy of Bile Duct
Biopsy
Biopsy of Bile Duct
Biopsy of Bile Duct
Immunohistochemical Test
Cytokeratin 5/6 Immunohistochemical Expression
CK 5/6 Immunohistochemical Expression
Cytokeratin 5/6 Expression
Cytokeratin 5/6 Immunohistochemical Expression
Cytokeratin 5/6 Immunohistochemical Expression
Laboratory Procedure
CK 5/6 Expression
C80497
Cytokeratin 5/6 Immunohistochemical Expression
owl:Class
owl:Class
Protein/Amino Acid Nutrition
CL002954
Nutrition, Protein/Amino Acids
Nutrition, Dietary Components
Nutrition, Protein/Amino Acids
Role of proteins and amino acids in cancer causation or prevention and in general health.
C15920
Nutrition, Protein/Amino Acids
Research Activity
Nutrition, Protein/Amino Acids
Phylogenetic Analysis
Research Technique
CL000713
C18940
Phylogenetic analysis is the study of evolutionary relationships among the many different kinds of life on earth, both living (extant) and dead (extinct). It includes creating evolutionary trees using computer programs.
Phylogenetic Analysis
Phylogenetic Analysis
owl:Class
Phylogenetics
Research Activity
Phylogenetic Analysis
CDISC
Blast to Leukocyte Ratio
Blast to Leukocyte Ratio
Blasts/Leukocytes
CL370391
BLASTLE
Laboratory Procedure
The determination of the ratio of blasts compared to leukocytes in a blood sample. The result may be expressed as either a ratio or a percentage.
CDISC SEND Terminology
Blood Cell Count Ratio Measurement
owl:Class
Clinical Data Interchange Standards Consortium Terminology
Blast to Leukocyte Ratio
Blast to Leukocyte Ratio
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Name
C64487
CDISC SDTM Laboratory Test Terminology by Code
<def-definition>A relative measurement (ratio or percentage) of the blasts to leukocytes in a biological specimen.</def-definition><def-source>CDISC</def-source>
C60718
Dental Restoration
owl:Class
Dental Procedure
CL360061
Therapeutic or Preventive Procedure
Dental Restoration
Dental Restoration
Dental Restoration
Replacement or reconstruction of a lost tooth structure.
Retrieval
Action
Retrieval
owl:Class
CL052639
C25659
Activity
Retrieval
The operation of accessing information or removing an item from storage.
Retrieval
CDISC SEND Terminology
CDISC
C0523961
Urea
Urea Measurement
owl:Class
Clinical Data Interchange Standards Consortium Terminology
A quantitative measurement of the amount of urea present in a sample.
CDISC SDTM Laboratory Test Terminology by Name
UREA
<def-source>CDISC</def-source><def-definition>A measurement of the urea in a biological specimen.</def-definition>
Urea Measurement
C64815
Renal Function Test
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
Urea Measurement
Laboratory Procedure
Urea Measurement
owl:Class
Photometry/Spectrum Analysis, X-ray/Neutron
Photometry/Spectrum Analysis, X-ray/Neutron
Laboratory Procedure
Photometry/Spectrum Analysis, X-ray/Neutron
Photometry/Spectrum Analysis, X-ray/Neutron
Spectroscopy
C18939
CL000711
Precursor Plasma Cell Count
owl:Class
PLSPCE
CDISC SDTM Laboratory Test Terminology by Name
CL384726
Blood Cell Count
Laboratory Procedure
Clinical Data Interchange Standards Consortium Terminology
CDISC SEND Terminology
Precursor Plasma Cell Count
Precursor Plasma Cell Count
C74619
Precursor Plasma Cell Count
CDISC
Plasmablast
CDISC SDTM Terminology
<def-source>CDISC</def-source><def-definition>A measurement of the precursor (blast stage) plasma cells (antibody secreting cells derived from B cells via antigen stimulation) in a biological specimen.</def-definition>
CDISC SDTM Laboratory Test Terminology by Code
The determination of the number of precursor plasma cells present in a sample.
Precursor Plasma Cells
owl:Class
C80413
Health Care Activity
Left Heart Catheterization
Left Heart Catheterization
Cardiac Catheterization
Left Heart Catheterization
Left Heart Catheterization
A diagnostic procedure in which a catheter is guided into the left heart, where pressures may be measured and radiocontrast material may be injected to visualize blood flow in and around the left heart.
Passive Immunization
Passive Immunization
Passive Immunization
owl:Class
<def-source>CSP2000</def-source><def-definition>use of antibodies or primed lymphocytes from an immune donor to produce immunity against an antigenic substance or organism in a nonimmune host.</def-definition>
C15259
<def-source>MSH2001</def-source><def-definition>Transfer of immunity from immunized to non-immune host by administration of serum antibodies, or transplantation of lymphocytes (ADOPTIVE TRANSFER).</def-definition>
Therapeutic or Preventive Procedure
Immunization
Passive Immunization
Adoptive Transfer
C0020974
Climbing
Climbing
Climbing
Physical Activity
Climb
owl:Class
The act of rising to a higher point.
Daily or Recreational Activity
Climbing
C81002
A quantitative measurement of the amount of conjugated or water-soluble bilirubin present in a sample of serum.
C0201916
Laboratory Procedure
Serum Chemistry Measurement
Serum Direct Bilirubin Measurement
Serum Direct Bilirubin Measurement
owl:Class
Serum Direct Bilirubin Measurement
C61024
Serum Direct Bilirubin Measurement
Direct Bilirubin Measurement
C63786
CL366190
Constant Normalization
Activity
Constant Normalization
Constant Normalization
Statistical Technique
Normalization to a Constant
owl:Class
Comparison of a variable factor to one with a fixed value (e.g., comparison of gene expression to a gene with constant expression).
Constant Normalization
Research Activity
Population Research
Maternal and Child Health Study
Maternal and Child Health Study
Maternal and Child Health Study
Studies focusing on the involvement of maternal factors (and efforts to modify these factors) that may affect the health of the child or fetus: smoking or exposure to drugs or toxic chemicals during pregnancy, maternal/fetal immunologic interactions.
CL000521
Maternal and Child Health Study
C15812
owl:Class
DNA Methylation Analysis
CL365247
Laboratory Procedure
owl:Class
DNA Methylation Analysis
DNA Methylation Analysis
Molecular Analysis
C63328
DNA Methylation Analysis
C64267
Two-Sided Test
Research Activity
Two-Sided Test
Two-Sided Test
Statistical Technique
2-Sided Test
Two-Sided Test
A statistical hypothesis test that controls directional errors if rejection of a hypothesis is the result of a directional decision. The two-sided test has less statistical power than the one-sided test.
owl:Class
CL369369
owl:Class
Similar to the human CGAP. The overall goals of the m-CGAP are: a comparative assessment of mouse cancer stages with those of cognate human cancers, both to validate the mouse models and to promote crossfeeding in the identification of genes that characterize those cancers; the discovery of new genes and gene pathways involved in the stages of carcinogenesis.
Research Activity
Mouse Cancer Genome Anatomy Project
Cancer Genome Anatomy Project
CL003276
Mouse CGAP
Mouse Cancer Genome Anatomy Project
Mouse Cancer Genome Anatomy Project
C15944
Mouse Cancer Genome Anatomy Project
Quantitative Concept
owl:Class
Negative Binomial Distribution
C0027558
C53209
A discrete statistical distribution whose variable has two possible values, "success" and "failure," and which describes the number of trials necessary to reach a predefined number of "successful" trials. The negative binomial distribution assumes that the trials are independent and that the probability of success does not vary from trial to trial.
Binomial Distribution
Negative Binomial Distribution
Negative Binomial Distribution
Negative Binomial Distribution
Intellectual Product
Media Campaign
owl:Class
C18227
Media Campaign
Media Campaign
Media Campaign
Public communication via television, radio, newspapers, pamphlets, telephone, and other media to influence health or social behaviors.
C0679720
Patient or Public Education
owl:Class
Multitest CMI is a diagnostic technique for detection of anergy (nonresponsiveness to antigens) by means of delayed hypersensitivity skin testing. This test uses seven antigens: tuberculin, tetanus, diphtheria, Streptococcus, Candida, Trichophyton, and Proteus to test for cutaneous delayed-type hypersensitivity responses in humans. The test is administered by pressing the antigen heads of the Multitest applicator firmly onto the volar surface of the lower arm. A positive reaction to an antigen is manifest as an inflammatory response at the site of administration.
Cell-Mediated Immunity Multitest
Immunology Test
CL110437
Cell-Mediated Immunity Multitest
C17996
Laboratory Procedure
Cell-Mediated Immunity Multitest
Cell-Mediated Immunity Multitest
Health Care Activity
Health Communication
Health Communication
Health Communication
owl:Class
Patient or Public Education
Health Communication
CL003997
C19355
CL066999
owl:Class
A surgical procedure to treat and correct deformities, diseases, and injuries to the skeletal system, its articulations, and associated structures.
Procedure_Has_Target_Anatomy only 'Skeletal System'
Orthopedic Surgical Procedures
Orthopedic Surgical Procedure
Therapeutic Surgical Procedure
Orthopedic Surgical Procedure
Surgical Procedure by Site or System
Orthopedic Surgical Procedure
Therapeutic or Preventive Procedure
C16186
Orthopedic Surgical Procedure
Diagnostic Procedure
Biopsy of Urethra
owl:Class
Removal of tissue from the urethra for microscopic examination.
Biopsy of Urethra
Biopsy
Procedure_Has_Partially_Excised_Anatomy only Urethra
CL354452
Biopsy of Urethra
Biopsy of Urethra
C51640
C81869
Immunoglobulin Measurement
Laboratory Procedure
Immunoglobulin Measurement
Immunoglobulin Measurement
Immunology Test
Immunoglobulin Measurement
The determination of the amount of immunoglobulin present in a sample.
owl:Class
Serum Glucose Measurement
Serum Chemistry Measurement
Serum Glucose Measurement
Serum Glucose Measurement
C0202041
A quantitative measurement of the amount of glucose present in a sample of serum.
C61027
Laboratory Procedure
Serum Glucose Measurement
owl:Class
owl:Class
Research Activity
A classification typically assigned retrospectively to a Phase III trial after regulatory authorities determined the need for a Phase III B trial.
CL355669
Trial Phase IIIA
Phase IIIa Trial
Clinical Data Interchange Standards Consortium Terminology
Phase IIIa Trial
Phase IIIa Trial
C49687
CDISC SDTM Trial Phase Terminology
Phase III Trial
3A
<def-source>CDISC</def-source><def-definition>A classification typically assigned retrospectively to a Phase III trial upon determination by regulatory authorities of a need for a Phase III B trial. (NCI)</def-definition>
CDISC SDTM Terminology
Phase IIIa Trial
Trial Phase 3A
CDISC
Immunology Test
Antigen Proliferation Assay
Antigen Proliferation Assay
An in vitro test to assess the ability of peripheral blood mononuclear cells to proliferate in response to specific antigen stimulus.
C17636
Antigen Proliferation Assay
Laboratory Procedure
Antigen Proliferation Assay
C0201614
owl:Class
Lymphocyte Proliferation Assay
An estimate of cumulative risk calculated over a lifetime.
Lifetime Risk
owl:Class
Risk Estimate
Lifetime Risk
Lifetime Risk
C19662
Clinical Attribute
Lifetime Risk
CL008202
Highly Active Antiretroviral Therapy
Drug therapy which targets retrovirus function by multiple mechanisms.
Antiviral Therapy
Highly Active Antiretroviral Therapy
C16165
HAART
Highly Active Antiretroviral Therapy
C0887947
Therapeutic or Preventive Procedure
Highly Active Antiretroviral Therapy
owl:Class
The determination of the amount of dronabinol present in a sample.
Laboratory Procedure
C75351
Dronabinol Measurement
Dronabinol Measurement
CL384484
owl:Class
Dronabinol Measurement
Cannabinoid Drug Class Measurement
Dronabinol Measurement
owl:Class
Creation of a visual window of the apex of the root that includes retrofilling the apical portion of the root canal.
CL371044
Apical Endodontic Surgery
Apical Endodontic Surgery
Apical Endodontic Surgery
Endodontic Treatment
Apical Endodontic Surgery
C66854
Tooth Extraction
Therapeutic or Preventive Procedure
Volume Measurement
Mixed Category Laboratory Procedure
CL384444
C74720
<def-definition>A measurement of the volume of a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
VOLUME
CDISC SDTM Laboratory Test Terminology by Name
The determination of the volume of a sample.
Volume
owl:Class
Volume Measurement
Volume Measurement
Volume Measurement
CDISC SDTM Terminology
Laboratory Procedure
CDISC SEND Terminology
Venous Phase Spiral CT
C19926
A type of computed tomography whereby images are taken at the venous phase post contrast medium injection. The venous phase is defined as the time period in which the contrast medium has passed the heart and the arterial blood vessels and has entered the venous blood vessel system.
Diagnostic Procedure
Venous Phase Spiral CT
CL012004
owl:Class
Venous Phase Spiral CT
Phased Spiral CT
Venous Phase Spiral CT
C67019
Parenteral Therapeutic Nutritional Supplementation
owl:Class
Parenteral Therapeutic Nutritional Supplementation
Therapeutic Nutritional Supplementation
Parenteral Therapeutic Nutritional Supplementation
Therapeutic or Preventive Procedure
CL371549
Parenteral Therapeutic Nutritional Supplementation
An estimate of serum calcium, corrected for the amount of albumin-bound calcium, used when albumin levels are not within normal ranges. It uses the formula: Corrected calcium (mg/dL) = measured total Ca (mg/dL) + 0.8 (4.0 - serum albumin [g/dL]), where 4.0 represents the average albumin level.
owl:Class
Corrected Serum Calcium Measurement
Corrected Serum Calcium Measurement
Corrected Serum Calcium
C74950
Serum Calcium Measurement
Corrected Serum Calcium Measurement
Laboratory Procedure
Corrected Serum Calcium Measurement
C0455288
The work of attending to someone or something.
C61488
Action
Care
Activity
Care
owl:Class
CL364826
Care
Care
The ratio of the odds of an event occurring in one group to the odds of it occurring in another group, or to a sample-based estimate of that ratio.
Risk Estimate
C0028873
An odds ratio of 1 indicates that the condition or event under study is equally likely in both groups. An odds ratio greater than 1 indicates that the condition or event is more likely in the first group. And an odds ratio less than 1 indicates that the condition or event is less likely in the first group.
Quantitative Concept
Odds Ratio
Odds Ratio
owl:Class
Odds Ratio
C16932
Odds Ratio
Protein or Enzyme Type Measurement
Sorbitol Dehydrogenase Measurement
C79465
<def-definition>A measurement of the sorbitol dehydrogenase in a biological specimen.</def-definition><def-source>CDISC</def-source>
Laboratory Procedure
SDH
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Laboratory Test Terminology by Code
The determination of the amount of sorbitol dehydrogenase present in a sample.
Clinical Data Interchange Standards Consortium Terminology
Sorbitol Dehydrogenase
CDISC SDTM Terminology
owl:Class
Sorbitol Dehydrogenase Measurement
Sorbitol Dehydrogenase Measurement
CDISC SEND Terminology
Sorbitol Dehydrogenase Measurement
Surgical Procedure by Method
Central Venous Cannula Insertion
Central Venous Cannula Insertion
C0398275
Central Venous Cannula Insertion
A procedure of surgical placement of a catheter, which lumen is usually occupied by a trocar, into the central vein (internal jugular, subclavian, and femoral often used) or veins, to provide vascular access for measurement of hemodynamic variables that cannot be measured accurately by noninvasive means. It also can be used to deliver medications that were too potent or too toxic to be administered through peripheral access, for parenteral nutrition delivery; and for placing wires and pulmonary artery catheters. Central veins are usually cannulated percutaneously. The procedure is associated with many adverse events and has to be performed or supervised by an experienced physician.
owl:Class
Therapeutic or Preventive Procedure
Central Venous Cannula Insertion
C40972
CL378230
Intravenous Pyelography
The creation of an image of the kidneys and urinary system using an intravenously administered contrast medium. By taking several X-rays over a short period of time, it is possible to check for the proper functioning of both kidneys and the urinary system.
Intravenous Pyelography
IVP
C20177
Intravenous Pyelography
<def-source>NCI-GLOSS</def-source><def-definition>(in-tra-VEE-nus pye-LAH-gra-fee) IVP. X-ray study of the kidneys, ureters, and bladder. The x-rays are taken after a dye is injected into a blood vessel. The dye is concentrated in the urine, which outlines the kidneys, ureters, and bladder on the x-rays.</def-definition>
intravenous pyelography
Diagnostic Procedure
Radiography
owl:Class
Intravenous Pyelography
owl:Class
C71494
Simple Random Sampling without Replacement
Simple Random Sampling without Replacement
Simple Random Sampling
CL378152
Quantitative Concept
Simple Random Sampling without Replacement
Simple Random Sampling without Replacement
Radioimmunoguided Surgery
Radioguided surgery is an innovative means by which a radionuclide is used to preoperatively image and intraoperatively visualize a structure of interest to the surgeon for excisional biopsy. This technology has allowed a cost-effective, highly specific means by which to locate a structure (usually a lymph node) and access it for pathologic analysis. The result of radioguided surgery is increased specificity in tissue obtained for biopsy, minimal access incisions, and the reduction of inpatient hospital utilization. (from Medscape)
Imaging Guided Therapy
owl:Class
CL031292
C15622
Radioguided Surgery
<def-source>NCI-GLOSS</def-source><def-definition>A procedure that uses radiolabeled substances to detect tumors for surgical removal.</def-definition>
Radioimmunoguided Surgery
Diagnostic Procedure
Surgical Procedure by Method
Therapeutic or Preventive Procedure
Radioimmunoguided Surgery
Radioimmunoguided Surgery
radioimmunoguided surgery
Light Scattering
Physical Chemical Technique
Light Scattering
Light Scattering
CL365208
Light Scattering
owl:Class
Dispersal of a beam of light into a range of directions as a result of physical interactions.
LS
Laboratory Procedure
C62323
DIP
Biomedical Imaging Program
Research Activity
Diagnostic Imaging Program
Diagnostic Imaging Program
C16046
Diagnostic Imaging Program
owl:Class
(1) Plans and coordinates the development; (2) coordinates the clinical testing of new approaches in academia, industry, or in other parts of the federal government; (3) coordinates the development targeted to specific biochemical or physiological processes in cancer cells for better biologic insight into the physiology of human tumors; (4) encourages industrial commitment to the development and ultimate clinical testing relevant to cancer; (5) coordinates activities with other programs of the Institute, other federal agencies, and outside organizations; (6) coordinates the activities of the branches within the Program for productive interactions and effective technology transfer; and (7) assesses the activities of the Program and advises the Division Director regarding scientific opportunities for the development of new approaches to the diagnosis and treatment of cancer.
C1511878
Cancer Research
Diagnostic Imaging Program
C0015252
Excision
The act of cutting out; the surgical removal of part or all of a structure or organ.
owl:Class
Extirpation
Diagnostic Procedure
C15232
Therapeutic or Preventive Procedure
Resection
Excision
Surgical Procedure by Method
resection
Surgical Removal
Removal
Abscission
<def-source>NCI-GLOSS</def-source><def-definition>(ree-SEK-shun) Removal of tissue or part or all of an organ by surgery.</def-definition>
excision
Excisional
Excision
Excision
The examination of the lymph nodes and lymphatic vessels following the injection of a radiopaque substance.
C0024219
Lymphangiography
Diagnostic Procedure
<def-source>NCI-GLOSS</def-source><def-definition>An x-ray study of lymph nodes and lymphatic vessels made visible by the injection of a special dye.</def-definition>
Angiography
lymphography
C38069
owl:Class
Lymphangiography
Lymphography
Lymphangiography
Lymphangiography
C0009244
C64345
CT
Psychotherapy
Therapeutic or Preventive Procedure
Cognitive Behavior Therapy
CBT
Cognitive Behavior Therapy
A type of psychotherapy utilized to treat different forms of mental disorders.The treatment involves the identification of unhelpful or destructive patterns of thinking and behaviors and the subsequent replacement with behaviors that are beneficial and constructive.
Cognitive Behavior Therapy
owl:Class
Cognitive Behavior Therapy
C52566
Conversion
Action
Conversion
Conversion
owl:Class
The act of changing the nature, form, function, or purpose of something to another.
C0439836
Activity
Conversion
conversion
Tissue Recombination
owl:Class
Research Activity
Tissue Recombination
A technique used in developmental biology to investigate the effects of one tissue upon another in induction of differentiation and tissue and organ formation. Basically, a piece of tissue is transplanted from its normal location to a new location. This helps to distinguish between intrinsic and extrinsic influences in organ formation.
C19831
Research Technique
CL008954
Tissue Recombination
Tissue Recombination
A type of nuclear test of the thyroid that measures how much radioactive iodine is taken up by the thyroid gland in a given time period. This test is performed to evaluate thyroid function, particularly when blood tests of thyroid function (for example, T3 or T4 levels) have abnormal results. (from Medline Plus Medical Encyclopedia)
I-131 Uptake Test
CL322433
I-131 Uptake Test
owl:Class
Radionuclide Imaging
I-131 Uptake Test
I 131 Uptake
Diagnostic Procedure
I-131 Uptake Test
Radioactive Iodine Uptake
C38088
I-131 Uptake and Scan
Biopsy
CL354466
Procedure_Has_Partially_Excised_Anatomy only 'Cervix Uteri'
Cervical Biopsy
Cervical Biopsy
C51628
Cervical Biopsy
owl:Class
Diagnostic Procedure
Removal of tissue from the cervix for microscopic examination.
Cervical Biopsy
Biopsy of Prostate
Removal of tissue from the prostate for microscopic examination.
Biopsy of Prostate
Biopsy of Prostate
Prostatic Biopsy
Biopsy
Diagnostic Procedure
owl:Class
CL354447
Biopsy of Prostate
Procedure_Has_Partially_Excised_Anatomy only 'Prostate Gland'
C51701
C53318
owl:Class
Measure of Central Tendency
Statistical Distribution Characteristic
CL356690
Quantitative Concept
Measure of Central Tendency
Measure of Central Tendency
Measure of Central Tendency
CL337398
Medical Imaging, X-Ray
owl:Class
Diagnostic Imaging
Radiography
X-Ray Imaging
Diagnostic Procedure
Conventional X-Ray
A radiographic procedure using the emission of x-rays to form an image of the structure penetrated by the radiation.
Radiography
C38101
X-Ray
Radiography
Diagnostic Radiology
Radiography
CL014098
Extraordinary Opportunities for Investment
Goal: we now have very focused targets against which to direct prevention and therapy efforts. The Molecular Targets Initiative will seek to discover and develop novel prevention, therapeutic, diagnostic, and imaging agents based on our understanding of these targets. (NCI Web)
Extraordinary Opportunity: Molecular Targets of Prevention and Treatment
C16138
Extraordinary Opportunity: Molecular Targets of Prevention and Treatment
Extraordinary Opportunity: Molecular Targets of Prevention and Treatment
From NCI Priority Web page: Identifying molecular differences between normal cells and cancer cells will enable us to develop a whole new generation of treatments and preventives that affect only cancer cells.
owl:Class
Extraordinary Opportunity: Molecular Targets of Prevention and Treatment
Research Activity
Thrombopoietin
Hormone Measurement
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Terminology
Laboratory Procedure
Clinical Data Interchange Standards Consortium Terminology
C74873
Thrombopoietin Measurement
The determination of the amount of thrombopoietin hormone present in a sample.
Thrombopoietin Measurement
owl:Class
Thrombopoietin Measurement
CDISC SEND Terminology
THRMPTN
CL384353
Thrombopoietin Measurement
CDISC SDTM Laboratory Test Terminology by Name
<def-definition>A measurement of the thrombopoietin hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
owl:Class
<def-definition>A relative measurement (ratio or percentage) of the eosinophils to leukocytes in a biological specimen.</def-definition><def-source>CDISC</def-source>
EOSLE
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Code
Eosinophil to Leukocyte Ratio
The determination of the ratio of eosinophils compared to leukocytes in a blood sample. The measurement may be expressed as a ratio or percentage.
Eosinophil to Leukocyte Ratio
Blood Cell Count Ratio Measurement
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Name
Eosinophil to Leukocyte Ratio
CDISC
CL370166
C64604
CDISC SDTM Terminology
Eosinophils/Leukocytes
Eosinophil to Leukocyte Ratio
Laboratory Procedure
Community Health Education
Draws on social relationships and organizations to reach large populations through media and interpersonal strategies that deliver messages and mechanisms to reduce chronic diseases.
C0009470
Community Health Education
Health Education
Community Education
Community Health Education
Health Care Activity
Community Health Education
owl:Class
C16455
Occult Blood
CDISC SEND Terminology
The determination of the amount of blood in body products such as a stool sample, that are not detectable on gross examination.
CDISC SDTM Laboratory Test Terminology by Name
C0028792
Occult Blood Measurement
Chemistry Test
Clinical Data Interchange Standards Consortium Terminology
CDISC
CDISC SDTM Laboratory Test Terminology by Code
C74686
CDISC SDTM Terminology
OCCBLD
owl:Class
Occult Blood Measurement
Laboratory Procedure
<def-source>CDISC</def-source><def-definition>A measurement of the blood in body products such as a stool sample, not detectable on gross examination.</def-definition>
Occult Blood Measurement
Occult Blood Measurement
Drug Therapy, Combination
owl:Class
combination chemotherapy
Chemotherapy, Combination
Therapeutic or Preventive Procedure
Combination Chemotherapy
Combination Chemotherapy
Combination Drug Therapy
Chemotherapy
C1521750
<def-source>NCI-GLOSS</def-source><def-definition>Treatment using more than one anticancer drug.</def-definition>
Combination Chemotherapy
C191
Combination Chemotherapy
FOBT
Screening Method
Hemoccult
Fecal Occult Blood Test
Stool guaiac test
owl:Class
Laboratory Procedure
Diagnostic Procedure
Fecal Occult Blood Test
A noninvasive test that detects the presence of hidden (occult) blood in the stool. This is commonly performed to screen for colon cancer.
Guaiac Smear Test
<def-source>NCI-GLOSS</def-source><def-definition>(FEE-kul o-KULT) A test to check for blood in stool. (Fecal refers to stool; occult means hidden.)</def-definition>
fecal occult blood test
C0201811
Fecal Occult Blood Test
Fecal Occult Blood Test
C18014
Diagnostic Procedure
Adrenal Blockade
owl:Class
Therapeutic or Preventive Procedure
C15472
Adrenal Blockade
CL029169
Adrenal Blockade
Endocrine Drug Therapy
Adrenal Blockade
Treatment to block production of adrenal hormones.
3C; Product Evaluation, Research, and Monitoring; Diagnostic Reagents and Test Kits (FMB)
Diagnostic Reagents and Test Kits
<def-source>MSH2001</def-source><def-definition>Commercially prepared reagent sets, with accessory devices, containing all of the major components and literature necessary to perform one or more designated diagnostic tests or procedures. They may be for laboratory or personal use.</def-definition>
Diagnostic Methods and Reagents
Medical Device
Diagnostic Reagents and Test Kits
C0034758
Diagnostic Reagents and Test Kits
Diagnostic Reagents and Test Kits
C15314
owl:Class
Indicator, Reagent, or Diagnostic Aid
Eigenvalue
Statistical Technique
Eigenvalue
A series of float values each of which represents proportion of variance for each principal component.
owl:Class
CL364531
Eigenvalue
C61068
Eigenvalue
Eigen Value
Quantitative Concept
Investigation of the component parts of a whole and the relationship between the parts, frequently using statistical methods, of a defined set of individuals or items (population).
owl:Class
Statistical Technique
Population Analysis
Population Analysis
CL000734
Population Analysis
Research Activity
Population Analysis
C18949
Research Activity
Maximum Likelihood Estimation
CL356481
Maximum Likelihood Estimation
Statistical Estimation
C53331
A method for estimating population characteristics based on limited data by choosing the sample values that make the data most likely to represent the general population.
owl:Class
Maximum Likelihood Estimation
Maximum Likelihood Estimation
Gamma-Hydroxybutyrate Measurement
The determination of the amount of gamma-hydroxybutyrate (GHB) present in a sample.
CL384497
CNS Depressant Drug Measurement
owl:Class
Laboratory Procedure
GHB Measurement
Gamma-Hydroxybutyrate Measurement
Gamma-Hydroxybutyrate Measurement
C75357
Gamma-Hydroxybutyrate Measurement
Organism Modification
owl:Class
Retrovirus
Retrovirus Insertion Modification
Research Activity
Retrovirus Insertion Modification
Retrovirus
C22495
CL331328
Retrovirus Insertion Modification
Retrovirus Insertion Modification
Organism modification caused by change in its genetic material brought about by retrovirus. The retrovirus constructs a DNA version of its genes using a special enzyme called reverse transcriptase and this DNA then becomes part of the cell's genetic material.
C80166
Laboratory Procedure
Alpha Glutathione-S-Transferase to Creatinine Ratio Measurement
The determination of the ratio of alpha glutathione-s-transferase compared to creatinine present in a sample. The measurement may be expressed as a ratio or percentage.
Alpha Glutathione-S-Transferase to Creatinine Ratio Measurement
Alpha Glutathione-S-Transferase to Creatinine Ratio Measurement
Protein or Enzyme Type Measurement
owl:Class
Alpha Glutathione-S-Transferase to Creatinine Ratio Measurement
Therapeutic or Preventive Procedure
Biologically Based Practices
C15250
Phytotherapy or Herbalism
Herbal Therapy
Botanical Therapy
Therapy based on plant-derived preparations which include the following: Individual herbs - Ginkgo biloba, Hypericum, Garlic, Ginseng, Echinacea, Saw palmetto, Urtica diocia (nettle), Kava kava, Hawthorne, Witch Hazel, Bilberry, Ginger, Aloe vera, Capsicum, Feverfew, Green tea, Tee Tree oil, Licorice root, Yohimbe, Valerian, Bee Pollen, Cat's Claw, Evening Primrose, Dong Quai, Fenugreek, Marshmallow, Psyllium, Turmeric. Combinations include: Padma 28, Hoxey, Essiac, Saw palmetto, Pygeum africanum.
Botanical Therapy
Botanical Therapy
C0019234
Herbal Medicine / Botanical Therapy
owl:Class
Botanical Therapy
Physiologic Testing
Physiologic Testing
Newborn Screening
Physiologic Testing
Study of Physiologic Variables
CL035533
owl:Class
C63481
Laboratory Procedure
Physiologic Test
Mixed Category Laboratory Procedure
Physiologic Testing
The determination of the amount of interleukin 32 present in a sample.
Interleukin 32 Measurement
CDISC SDTM Terminology
INTLK32
owl:Class
CL384311
C74830
Interleukin 32 Measurement
CDISC SDTM Laboratory Test Terminology by Name
Interleukin 32
Interleukin 32 Measurement
<def-definition>A measurement of the interleukin 32 in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SEND Terminology
Interleukin 32 Measurement
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Code
Laboratory Procedure
Cytokine Measurement
Tumor Necrosis Factor Measurement
Tumor Necrosis Factor Measurement
Tumor Necrosis Factor Measurement
Protein or Enzyme Type Measurement
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Code
C74751
CDISC
Clinical Data Interchange Standards Consortium Terminology
TNF
CL384717
CDISC SDTM Laboratory Test Terminology by Name
The determination of the amount of tumor necrosis factor present in a sample.
<def-source>CDISC</def-source><def-definition>A measurement of the total tumor necrosis factor (cachexin) cytokine in a biological specimen.</def-definition>
owl:Class
Tumor Necrosis Factor
Laboratory Procedure
Tumor Necrosis Factor Measurement
CDISC SDTM Terminology
Prevention Study
Prevention Study
Trial Indication Type
Research Activity
Prevention Study
CDISC
Preventive Clinical Trial
owl:Class
CDISC SDTM Trial Indication Type Terminology
Clinical Data Interchange Standards Consortium Terminology
CL355660
<def-source>CDISC</def-source><def-definition>A type of study designed to identify actions necessary to permanently eliminate or reduce the long-term risk to human life as a result of a particular medication or treatment regimen.</def-definition>
PREVENTION
A type of study protocol designed to evaluate intervention(s) for disease prevention.
CDISC SDTM Terminology
Prevention Study
C49657
C16233
CL084340
owl:Class
Macronutrients
Nutrition, Dietary Components
Nutrition, Macronutrients
Nutrition, Macronutrients
Nutrition, Macronutrients
Research Activity
Nutrition, Macronutrients
Therapeutic or Preventive Procedure
Pleurodesis
Therapeutic Surgical Procedure
Pleurodesis
Thoracic Surgical Procedure
owl:Class
Pleurodesis
Pleurodesis
C0189557
C66899
Dose Reduced
<def-source>CDISC</def-source><def-definition>An indication that a medication schedule was modified by subtraction, either by changing the frequency, strength or amount. (NCI)</def-definition>
Activity
owl:Class
CL354501
Clinical Data Interchange Standards Consortium Terminology
Action Taken with Study Treatment
Dose Reduced
Dose Reduced
Dose Reduced
An indication that a medication schedule was modified by subtraction, either by changing the frequency, strength or amount.
CDISC SDTM Terminology
CDISC SDTM Action Taken with Study Treatment Terminology
C49505
DOSE REDUCED
CDISC
CL387503
Support Vector Machine
owl:Class
Support Vector Machine
Support Vector Machine
Support Vector Machine
A classification method that will construct a hyperplane between two sets of data such that it maximizes the margin between the hyperplane and the nearest samples.
Statistical Technique
Quantitative Concept
C78542
Pulse Rate
Pulse Rate
Pulse Rate
Newborn Screening
CDISC SDTM Vital Sign Terminology by Code
C49676
CDISC SDTM Vital Sign Terminology by Name
CDISC SDTM Terminology
The rate of the pulse as observed in an artery, expressed as beats per minute. It can be measured at several anatomical sites, including the wrist, neck, temple, groin, behind the knees, or on top of the foot.
Quantitative Concept
Vital Signs
CDISC
C0232117
Clinical Data Interchange Standards Consortium Terminology
Pulse Rate
owl:Class
<def-source>CDISC</def-source><def-definition>The rate of the pulse as observed in an artery, expressed as beats per minute. It can be measured at several anatomical sites, including the wrist, neck, temple, groin, behind the knees, or on top of the foot. (NCI)</def-definition>
PULSE
<def-source>CDISC</def-source><def-definition>A type of study protocol designed to evaluate intervention(s) aimed to cure a disease or condition. (NCI)</def-definition>
CDISC
owl:Class
A type of study protocol designed to evaluate intervention(s) aimed to cure a disease or condition.
Trial Indication Type
CDISC SDTM Terminology
C49654
Cure Study
Cure Study
CL353297
CDISC SDTM Trial Indication Type Terminology
Cure Study
Clinical Data Interchange Standards Consortium Terminology
Cure Study
Research Activity
CURE
owl:Class
The activities of educating or instructing or teaching that are directed towards a patient or the general public.
Patient/Public Education About Cancer
Educational Activity
Patient or Public Education
Patient or Public Education
C19141
Patient or Public Education
Educational Activity
Patient or Public Education
CL001147
A technique for the separation of complex mixtures that relys on the differential affinities of substances for a gas or liquid mobile medium and for a stationary adsorbing medium through which they pass.
C0008550
C16431
Chromatography / Separation Science
Research Technique
owl:Class
<def-source>MSH2001</def-source><def-definition>Any of a diverse group of techniques used to separate mixtures of substances based on differences in the relative affinities of the substances for two different media, one (the mobile phase) a moving fluid and the other (the stationary phase or sorbent) a porous solid or gel or a liquid coated on a solid support. The speed at which each substance is carried along by the mobile phase depends on its solubility (in a liquid mobile phase) or vapor pressure (in a gas mobile phase) and on its affinity for the sorbent. (Dorland, 27th ed)</def-definition>
Chromatography
Chromatography
Chromatography
Laboratory Procedure
Chromatography
Dispense as Written
CL370153
C64648
D.A.W.
Activity
owl:Class
Dispense as Written
Dispense as Written
Dispense as Written
Dispense
The distribution of the ratio of two independent quantities each of which is distributed like a variance in a normally distributed sample.
CL356433
Continuous Distribution
F-Distribution
F-Distribution
F Distribution
F-Distribution
C53221
Quantitative Concept
owl:Class
F-Distribution
Immunoglobulin E Measurement
Immunoglobulin Measurement
Immunoglobulin E Measurement
Immunoglobulin E Measurement
owl:Class
Immunoglobulin E Measurement
The determination of the amount of immunoglobulin E present in a sample.
C81970
CL322425
Nasopharyngeal Laryngoscopy
Nasopharyngeal Laryngoscopy
Nasopharyngeal Laryngoscopy
Nasopharyngeal Laryngoscopy
owl:Class
Laryngoscopy
Endoscopic examination of the larynx, via the nasopharynx.
Diagnostic Procedure
C38074
CL360086
Laser Fluorescence
A method used to aid in the detection of tooth decay by measuring fluorescence using a laser.
Therapeutic or Preventive Procedure
owl:Class
Dental Procedure
Laser Fluorescence
Laser Fluorescence
Laser Fluorescence
C60724
Standard Deviation
A measure of the range of values in a set of numbers. Standard deviation is a statistic used as a measure of the dispersion or variation in a distribution, equal to the square root of the arithmetic mean of the squares of the deviations from the arithmetic mean.
SD
Standard Deviation
owl:Class
Dispersion
Quantitative Concept
C53322
Standard Deviation
CL385535
Standard Deviation
owl:Class
Prevention of Gastric Cancer
Cancer Prevention
C15734
Prevention of Gastric Cancer
Prevention of Gastric Cancer
Therapeutic or Preventive Procedure
CL032136
Prevention of Gastric Cancer
Percent Free Prostate-Specific Antigen
owl:Class
CL014594
Quantitative Concept
Percent Free Prostate-Specific Antigen
C20042
Prostate Specific Antigen Measurement
Percent Free Prostate-Specific Antigen
Percent Free Prostate-Specific Antigen
PSA circulates in the blood in two forms: free or attached to a protein molecule. With benign prostate conditions, there is more free PSA, while cancer produces more of the attached form. A more accurate predictor of cancer than either a patient's age or his total PSA level. (from Cancer Information Service)
C74798
Macrophage Measurement
owl:Class
Cell Count
Macrophage Measurement
Macrophage Measurement
Macrophage Measurement
The determination of the number of macrophages present in a sample.
CL384410
Laboratory Procedure
C17160
<def-source>NCI-GLOSS</def-source><def-definition>(eh-SOF-a-JEE-al) Speech produced by trapping air in the esophagus and forcing it out again. It is used after removal of a person's larynx (voice box).</def-definition>
Esophageal Speech
C0037834
Esophageal Speech
Esophageal Speech
Speech, Esophageal
Esophageal Speech
Individual Behavior
esophageal speech
Alaryngeal Speech
owl:Class
owl:Class
Clinical Attribute
Prior Hormone Therapy
CL014948
Prior Hormone Therapy
Prior Hormone Therapy
Prior Hormone Therapy
Prior Therapy
prior hormonal therapy
C16175
Total Marrow Irradiation
Total Marrow Irradiation
owl:Class
Therapeutic or Preventive Procedure
Bone Marrow Ablation
Total Marrow Irradiation
CL378646
C72183
Total Marrow Irradiation
Prostatectomy
C15307
C0033573
Therapeutic or Preventive Procedure
Surgical removal of part or all of the prostate.
Prostatectomy
Prostatectomy
Prostatectomy
<def-source>NCI-GLOSS</def-source><def-definition>(pros-ta-TEK-toe-mee) An operation to remove part or all of the prostate. Radical (or total) prostatectomy is the removal of the entire prostate and some of the tissue around it.</def-definition>
owl:Class
Procedure_Has_Excised_Anatomy only 'Prostate Gland'
Urologic Surgical Procedure
prostatectomy
owl:Class
Efficacy Study
Trial Type
Efficacy Study
CDISC SDTM Terminology
A study of the relative therapeutic efficacy of treatment of a disease. Usually this is a Phase II or III study.
CDISC
C49666
Efficacy Study
Research Activity
Clinical Data Interchange Standards Consortium Terminology
<def-source>CDISC</def-source><def-definition>A study of the relative therapeutic efficacy of treatment of a disease. Usually this is a Phase II or III study. (NCI)</def-definition>
CDISC SDTM Trial Type Terminology
EFFICACY
CL354530
Efficacy Study
owl:Class
C15496
positive progesterone receptor
<def-source>NCI-GLOSS</def-source><def-definition>Progesterone receptor positive. Breast cancer cells that have a protein (receptor molecule) to which progesterone will attach. Breast cancer cells that are PR+ need the hormone progesterone to grow and will usually respond to hormonal therapy.</def-definition>
Progesterone Receptor Positive
progesterone receptor positive
Progesterone Receptor Status
Progesterone Receptor Positive
PR+
Clinical Attribute
Progesterone Receptor Positive
<def-source>NCI-GLOSS</def-source><def-definition>(PR+) PR+. Breast cancer cells that have a protein (receptor molecule) to which progesterone will attach. Breast cancer cells that are PR+ need the hormone progesterone to grow and will usually respond to hormonal therapy.</def-definition>
CL054583
Progesterone Receptor Positive
Dental Procedure
owl:Class
Any of the dental diagnostic, preventive, and restorative services provided to meet the needs of a patient.
Therapeutic Procedure
C38052
C0011331
Health Care Activity
Dental Procedure
Dental Procedure
Dental Procedure
C1522643
Acid Fast Bacillae
The use of acid-fast stain to examine a specimen for the presence of acid-fast microorganisms, specifically mycobacteria.
Acid Fast Bacillae Staining Method
AFB
C23015
Acid-fast bacteria resist decoloration with acid-alcohol and will stain red, while other bacteria in the specimen will stain blue.
Acid Fast Bacillae Staining Method
Acid Fast Bacillae Staining Method
Acid Fast Bacillae Staining Method
Laboratory Procedure
Special Histology Staining Method
owl:Class
Acid Fast
Acid Fast Bacillae Staining Method
Clinical Attribute
CL029665
Prior Hormone Therapy
Prior Progestin Therapy
owl:Class
Prior Progestin Therapy
Prior Progestin Therapy
Prior Progestin Therapy
C15502
C48310
Manipulation
owl:Class
Manipulation
Activity
Manipulate
Action
Manipulative
Move, treat, or operate with the hands or by mechanical means, especially in a skillful manner.
C0947647
Manipulation
Manipulation
Vasopressin
Clinical Data Interchange Standards Consortium Terminology
C0201849
owl:Class
CDISC SEND Terminology
Antidiuretic Hormone Measurement
C74847
Antidiuretic Hormone Measurement
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Terminology
Hormone Measurement
The determination of the amount of antidiuretic hormone present in a sample.
Antidiuretic Hormone
Antidiuretic Hormone Measurement
<def-definition>A measurement of the antidiuretic hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
ADH
Antidiuretic Hormone Measurement
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Name
C0599772
Gene Knockout
Refers to the targeted disruption of a gene within its normal biological context. Utilized to examine the involvement of a gene in a complex biological process.
owl:Class
Gene Knockout
Molecular Biology Research Technique
C18143
Molecular Genetic Technique
Gene Knockout
Gene Knockout
Probe Correction Method
C64231
MAS Probe Correction Method
Activity
CL369296
MAS Probe Correction Method
MAS Probe Correction Method
owl:Class
MAS Probe Correction Method
Correct perfect match (PM) probe levels using the ideal mismatch algorithm. Defined in the documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html.
owl:Class
C15533
Chemoprotection
Chemoprotection
The use of drugs to protect normal tissue from damage by cancer therapy agents.
Chemoprotection
CL030373
Therapeutic Procedure
Chemoprotection
Therapeutic or Preventive Procedure
Air Blast
Dental Procedure
Health Care Activity
owl:Class
Air Blast
A short burst of air.
Air Blast
Air Blast
C82101
Radioisotope Therapy
C15355
Radioimmunotherapy
<def-source>NCI-GLOSS</def-source><def-definition>Treatment with a radioactive substance that is linked to an antibody that will attach to the tumor when injected into the body.</def-definition>
Immunotherapy, Cancer, Radioisotope
<def-source>MSH2001</def-source><def-definition>Radiotherapy where cytotoxic radionuclides are linked to antibodies in order to deliver toxins directly to tumor targets. Therapy with targeted radiation rather than antibody-targeted toxins (IMMUNOTOXINS) has the advantage that adjacent tumor cells, which lack the appropriate antigenic determinants, can be destroyed by radiation cross-fire. Radioimmunotherapy is sometimes called targeted radiotherapy, but this latter term can also refer to radionuclides linked to non-immune molecules (see RADIOTHERAPY).</def-definition>
Immunoradiotherapy
radioimmunotherapy
Therapeutic or Preventive Procedure
Radioimmunotherapy
Treatment with a radioactive substance that is linked to an antibody so that it will attach to a tumor when injected into the body.
owl:Class
Radioimmunotherapy
Radioimmunotherapy
C0085101
Cancer Immunotherapy
Antibody Therapy
Quantitative Concept
Birth Rate
Birth Rate
The ratio of live births in an area to the population of that area, expressed per 1000 people in the population per year.
Population-Based Statistic
owl:Class
Birth Rate
C53345
Birth Rate
C0005608
Sort
Sorting
C62803
Action
Activity
An operation that segregates items into groups according to a specified criterion.
owl:Class
Sorting
Sorting
Sorting
Sorted
CL365885
C61367
Induction
Action
Inducible
Induced
Induction
Induction
owl:Class
The act of bringing about something.
Inducing
Induce
Induction
CL385249
Activity
Action
Instruction Imperative
Individual Case Safety Report Terminology
Type Of Remedial Action ICSR Terminology
Notification
FDA
owl:Class
C25297
Notification
Activity
Notification
Informing by words.
Notification
Notify
C0422202
Submission
Submission
The act of referring for judgment or consideration by others; the act of handing over something.
CL052725
Functional Concept
Submission
C25695
Action
Submission
owl:Class
Submitted
Urogenital Surgical Procedure
Genitourinary System Surgical Procedure
Urogenital Surgical Procedure
Surgical Procedure by Site or System
Urogenital Surgical Procedure
Urogenital Surgery
C15333
Therapeutic or Preventive Procedure
Any surgery to the urinary system or its parts.
owl:Class
Procedure_Has_Target_Anatomy only 'Genitourinary System'
C0038912
Surgery, Genitourinary
Urogenital Surgical Procedure
Study
Research Activity
Study
Study
C0947630
owl:Class
Study
Research Activity
A detailed examination, analysis, or critical inspection of a subject designed to discover facts about it.
C63536
Transplantation of Liver
Hepatic Transplantation
Therapeutic or Preventive Procedure
<def-source>MSH2001</def-source><def-definition>The transference of a part of or an entire liver from one human or animal to another.</def-definition>
owl:Class
Liver Transplantation
Liver Transplantation
Digestive System Surgery
Liver Grafting
Liver Transplantation
C15271
C0023911
Liver Transplantation
Procedure_Has_Target_Anatomy only Liver
Organ Transplantation
CL000585
1B; Basic Science Research (includes vaccine and chemotherapy development), Neuroscience And Neuropsychiatric Research
C15817
Neuroscience and Neuropsychiatric Research
Basic Science Research
Neuroscience and Neuropsychiatric Research
Research Activity
owl:Class
Neuroscience and Neuropsychiatric Research
Neuroscience and Neuropsychiatric Research
Steroid Measurement
Steroid Measurement
Laboratory Procedure
Steroid Measurement
C75345
The determination of the amount of any steroid present in a sample.
C1295084
Steroid Measurement
owl:Class
Drug Class Measurement
Ventricular Ablation
Ventricular Ablation
Ventricular Ablation
owl:Class
Ventricular Ablation
Therapeutic or Preventive Procedure
Cardiac Therapeutic Procedure
C80433
Ablation Therapy
A invasive therapeutic procedure in which a catheter is threaded through veins into the cardiac ventricles to destroy the tissue that is the source of an arrhythmia.
Smoking Cessation
Smoking Cessation
Individual Behavior
C17427
Smoking Cessation
owl:Class
Discontinuation of the habit of smoking.
Smoking Cessation
C0085134
Smoking Behavior
Endocrine Therapy
Chemotherapy-Hormones/Steroids
Hormonal Therapy
Hormone Therapy
Endocrine Therapy
Therapeutic or Preventive Procedure
endocrine therapy
Endocrine Therapy
Therapeutic Procedure
Endocrine Therapy
hormone therapy
The concept covers but is not limited to: intermittent or permanent hormone suppression or ablation in treatment of hormone-dependent tumors, hormone replacement therapy of any kind, hormonal component of gender reassignment therapy, hormonal contraception, surgical and radiation castration.
hormonal therapy
Various treatment modalities that produce the desired therapeutic effect by means of change of hormone/hormones level. The treatment may include administration of hormones or hormone analogs to the patient, or decreasing the level of hormones in the body by using hormone antagonists, or hormone ablation therapy.
<def-source>NCI-GLOSS</def-source><def-definition>Treatment that adds, blocks, or removes hormones. For certain conditions (such as diabetes or menopause), hormones are given to adjust low hormone levels. To slow or stop the growth of certain cancers (such as prostate and breast cancer), hormones may be given to block the body's natural hormones. Sometimes surgery is needed to remove the source of hormones.</def-definition>
owl:Class
C0279025
C15445
owl:Class
Clinical Trials, Other
CL012657
Clinical Trial, Other
Other Clinical Trial
C16123
Clinical Trial
Clinical Trial, Other
A clinical trial that is not therapeutic, preventive or diagnostic.
Research Activity
Clinical Trial, Other
Clinical Trial, Other
Action
Feed
To move something gradually into or through.
Feed
owl:Class
Activity
CL375672
Feed
C69427
Feed
Lithography that is performed on a nanoscale. Examples of this technique include etching, writing and printing on nanoscale surfaces.
CL364919
Non-Clinical Nanoparticle Application
Nanolithography
C62316
Nanolithography
owl:Class
Activity
Nanolithography
Nanolithography
Therapeutic or Preventive Procedure
C15752
Chemoembolization
Chemoembolization
<def-source>NCI-GLOSS</def-source><def-definition>A procedure in which the blood supply to the tumor is blocked surgically or mechanically and anticancer drugs are administered directly into the tumor. This permits a higher concentration of drug to be in contact with the tumor for a longer period of time.</def-definition>
C0796679
chemoembolization
Chemotherapy
owl:Class
Embolization Therapy
Chemoembolization
TACE
Chemotherapy Embolization
Chemoembolization
Protein or Enzyme Type Measurement
Newborn Screening
The measurement of the galactose-1-phosphate uridyltransferase in a biologic specimen.
Galactose-1-Phosphate Uridyltransferase Measurement
Galactose-1-Phosphate Uridyltransferase Measurement
Laboratory Procedure
owl:Class
C81251
Galactose-1-Phosphate Uridyltransferase Measurement
Galactose-1-Phosphate Uridyltransferase Measurement
Breast Self-Examination
Breast Self-Examination
Procedure where the individual examines their own breasts for lumps and other changes.
C70551
Breast Self-Examination
Breast Self-Surveillance
C0085105
owl:Class
Breast Self-Examination
Self-Examination
Individual Behavior
Median Polish
Bioconductor caAffy Median Polish Probe Summary Method
C64225
Probe Summary Method
CL369067
Bioconductor caAffy Median Polish Probe Summary Method
Bioconductor caAffy Median Polish Probe Summary Method
Median Polish Probe Summary Method
Summarizes probe sets using Tukey's median polish procedure. Defined in the documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html.
Activity
owl:Class
Bioconductor caAffy Median Polish Probe Summary Method
Stratified Simple Random Sampling
Stratified Simple Random Sampling
Simple Random Sampling
Stratified Simple Random Sampling
CL356548
C53197
Stratified Simple Random Sampling
Stratified Random Sampling
owl:Class
Quantitative Concept
Maximum Variation Sampling
Matched Sampling
Quantitative Concept
Maximum Variation Sampling
Maximum Variation Sampling
C71506
owl:Class
Maximum Variation Sampling
CL378048
Infection Prophylaxis and Management
infectious diseases treatment
Infection Prophylaxis and Management
C15511
Infectious Diseases / Treatment, General
Therapeutic or Preventive Procedure
management, infection prophylaxis
Infection Prophylaxis and Management
Treat infections with antibacterial, antifungal, antiparasite or antiviral drugs
Treatment of Infectious Disease
Health Care Activity
owl:Class
Supportive Care
CL029832
Infection Prophylaxis and Management
Laboratory Procedure
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Name
Liver Function Test
Protein or Enzyme Type Measurement
Gamma Glutamyl Transferase
owl:Class
CDISC
A quantitative measurement of the amount of gamma glutamyl transpeptidase present in a sample.
CDISC SDTM Laboratory Test Terminology by Code
Gamma Glutamyl Transpeptidase Measurement
C64847
Gamma Glutamyl Transpeptidase Measurement
CDISC SEND Terminology
Gamma Glutamyl Transpeptidase Measurement
GGT
GGTP
Gamma Glutamyl Transpeptidase Measurement
Clinical Data Interchange Standards Consortium Terminology
<def-definition>A measurement of the gamma glutamyl transferase in a biological specimen.</def-definition><def-source>CDISC</def-source>
C0202035
Activity
Cover
owl:Class
Coverage
Action
Span a region or interval of distance, space or time.
C0439844
Cover
C68811
Cover
Cover
Covered
C15776
Cancer Detection
The act of discovery of a malignant neoplasm, and after treatment, the discovery of minimal residual disease.
owl:Class
Diagnostic Procedure
Cancer Detection
Cancer Detection
Cancer Detection
CL000144
Detection
owl:Class
Medical or surgical interventions to eradicate breast tumors and/or their metastases.
Breast Cancer Treatment
Breast Cancer, Treatment
Cancer Therapeutic Procedure
Breast Cancer Therapeutic Procedure
CL000129
Breast Cancer Therapeutic Procedure
Breast Cancer Therapeutic Procedure
C15774
Breast Cancer Diagnostic or Therapeutic Procedure
Breast Cancer Therapeutic Procedure
Therapeutic or Preventive Procedure
BRCA1 Mutation Analysis
BRCA1 Mutation Analysis
BRCA1 Status Determination
Laboratory Procedure
C80498
owl:Class
Mutation Analysis
BRCA1 Mutation Analysis
BRCA1 Mutation Analysis
CL354288
Removal of tissue through the bronchial wall, for microscopic examination.
Transbronchial Lung Biopsy
Transbronchial Lung Biopsy
C51749
Diagnostic Procedure
Lung Biopsy
owl:Class
Transbronchial Lung Biopsy
Transbronchial Lung Biopsy
Procedure_Has_Partially_Excised_Anatomy only Bronchus
C0031765
<def-source>MSH2001</def-source><def-definition>Treatment of disease by exposure to light, especially by variously concentrated light rays or specific wavelengths.</def-definition>
Phototherapy
The treatment of a disorder by exposure to light, including ultraviolet and infrared radiation. (Bartleby.com)
Therapeutic or Preventive Procedure
owl:Class
Phototherapy
Actinotherapy
C15301
Therapeutic Procedure
Phototherapy
Phototherapy
Procedure_May_Have_Completely_Excised_Anatomy some 'Left Breast'
Mastectomy
Contralateral Prophylactic Mastectomy
Contralateral Prophylactic Mastectomy
Contralateral Prophylactic Mastectomy
Surgical removal of a non-diseased breast along with a cancerous one to reduce the risk of future breast carcinoma.
Procedure_May_Have_Completely_Excised_Anatomy some 'Right Breast'
C46070
Therapeutic or Preventive Procedure
CL342949
owl:Class
Contralateral Prophylactic Mastectomy
CPM
Calcium Oxalate Crystal Measurement
C74670
CYCAOXA
CDISC SDTM Laboratory Test Terminology by Code
owl:Class
Calcium Oxalate Crystals
CDISC SEND Terminology
CDISC
CDISC SDTM Terminology
<def-source>CDISC</def-source><def-definition>A measurement of the calcium oxalate crystals present in a biological specimen.</def-definition>
CL384769
Calcium Oxalate Crystal Measurement
Clinical Data Interchange Standards Consortium Terminology
Crystal Growth Measurement
Calcium Oxalate Crystal Measurement
The determination of the amount of calcium oxalate crystals present in a sample.
CDISC SDTM Laboratory Test Terminology by Name
Calcium Oxalate Crystal Measurement
Laboratory Procedure
owl:Class
Activity
Action
Treat
Subject to a process with the aim of readying for some purpose, improving, or remedying a condition.
Treatment
Treat
C70742
Treated
Treat
Treat
CL376088
C81295
Laboratory Procedure
Thyroid Stimulating Hormone Measurement
Thyroid Stimulating Hormone Measurement
Newborn Screening
Thyroid Stimulating Hormone Measurement
Thyroid Stimulating Hormone Measurement
Hormone Measurement
The determination of the amount of thyroid stimulating hormone (TSH) present in a sample.
owl:Class
H-Wave Therapy
H-Wave Therapy
A non-invasive form of electroanalgesia produces a direct, localized effect on the conduction of underlying peripheral nerves. It is often used for dental analgesia, treatment of acute musculoskeletal injuries, postoperative pain, local analgesia, and in treatment of diabetic patients with peripheral neuropathic pain. (from White, Li, and Chiu)
HWT
CL100600
Therapeutic or Preventive Procedure
owl:Class
H-Wave Therapy
H-Wave Therapy
C21029
Electroanalgesia
Coagulation Study
Reptilase Time
Reptilase Time
C80366
owl:Class
Laboratory Procedure
Reptilase Time
Reptilase Time
A measurement of the time it takes a plasma sample to clot after adding the snake venom enzyme batroxobin (reptilase). This procedure can be used to detect deficiencies or abnormalities in fibrinogen and this enzyme is resistant to both endogenous thrombin inhibitors and heparin.
Inferred
Inference
Action
C0679201
Inference
Inference
Inference
Activity
owl:Class
C75591
The process by which conclusions are derived from stated facts by the application of logical rules.
Radionuclide Imaging
Gallium Scan
A nuclear imaging procedure in which gallium-67 is used as the radiopharmaceutical. Gallium binds to transferrin, leukocyte lactoferrin, bacterial siderophores and inflammatory proteins and thereby can be used to localize foci of infection. It is also taken up by several tumors, thus gallium scintigraphy can be used for the staging of tumors.
Gallium Scan
Gallium Scan
C0521316
Diagnostic Procedure
C38087
owl:Class
Gallium Scan
Research Activity
Technique
Modeling
CL008180
Modeling
Modeling
Modeling
C16063
owl:Class
The use of statistical analysis, computer analysis, or model organisms to predict outcomes of research. (doegenomes.org)
Organ Transplantation
Skin Transplantation
C15325
Skin Transplantation
Therapeutic or Preventive Procedure
C0037297
owl:Class
skin grafting
dermatoplasty
<def-source>MSH2001</def-source><def-definition>The grafting of skin in humans or animals from one site to another to replace a lost portion of the body surface skin.</def-definition>
Skin Transplantation
Skin Transplantation
Mixed Category Laboratory Procedure
C0026018
The application of microscope magnification to the study of materials that cannot be properly seen by the unaided eye.
Microscopy
Microscopy
C16853
<def-source>MSH2001</def-source><def-definition>The application of microscope magnification to the study of materials that cannot be properly seen by the unaided eye.</def-definition>
Microscopy
Microscopy
Laboratory Procedure
owl:Class
C22491
Mouse Model Model
CL324534
Research Activity
Knock-out
Knock-out
Inactivation of specific genes by homologous recombination. Knockouts are often created in laboratory organisms such as yeast or mice so that scientists can study the knockout organism as a model for a particular disease.
Knock-out
Knockout
Knock-out
Knock-out
owl:Class
Organism Modification
Central Nervous System Prophylaxis
Therapeutic Procedure
<def-source>NCI-GLOSS</def-source><def-definition>(pro-fih-LAK-sis) Chemotherapy or radiation therapy given to the central nervous system (CNS) as a preventive treatment. It is given to kill cancer cells that may be in the brain and spinal cord, even though no cancer has been detected there.</def-definition>
CL002844
Central Nervous System Prophylaxis
Central Nervous System Prophylaxis
Therapeutic or Preventive Procedure
CNS prophylaxis
Central Nervous System Prophylaxis
CNS Prophylaxis
owl:Class
C15916
Occupational Activity
C64202
Smoothing
owl:Class
Smoothing
Smoothed
Statistical Technique
CL369375
The modification of a set of data to make it smooth and nearly continuous and remove or diminish outlying points.
Smoothing
Smoothing
owl:Class
Instruction Imperative
Stir
Stir
Stir
C64645
Activity
Stir
CL370500
Immunoprecipitation
Laboratory Procedure
Co-Immunoprecipitation
CL008952
C19830
Co-immunoprecipitation (Co-IP) is a popular technique for protein interaction discovery. In a co-IP the target antigen precipitated by the antibody "co-precipitates" a binding partner/protein complex from a lysate. It is assumed that these proteins are related to the function of the target antigen at the cellular level.
Co-Immunoprecipitation
owl:Class
Co-Immunoprecipitation
Co-Immunoprecipitation
Depigmentation Therapy
Therapeutic Procedure
CL029165
C15468
Depigmentation Therapy
Depigmentation Therapy
Depigmentation Therapy
owl:Class
Therapeutic or Preventive Procedure
owl:Class
Total Colectomy
C51924
Therapeutic or Preventive Procedure
Total Colectomy
CL354280
Procedure_Has_Completely_Excised_Anatomy only Colon
Surgical removal of the entire colon.
Complete Excisioin of Colon
Total Colectomy
Colectomy
Total Colectomy
Laboratory test involving interaction of antigens with specific antibodies.
C0021060
C16723
Immunology Test
Immunological Laboratory Method
owl:Class
Immunology Test
Immunology Test
Clinical Pathology Procedure
Laboratory Procedure
Immunology Test
Therapeutic or Preventive Procedure
C0547070
Removal, separation, detachment, extirpation, or eradication of a body part, pathway, or function by surgery, chemical destruction, morbid process, or noxious substance.
Therapeutic Procedure
owl:Class
Ablation
Ablation Therapy
Ablation Therapy
Ablation Therapy
Ablation Therapy
C20985
CL369366
Systemic Chemotherapy
Systemic Chemotherapy
Therapeutic or Preventive Procedure
Systemic Chemotherapy
C64261
Chemotherapy
owl:Class
Systemic Chemotherapy
Local Anesthesia Procedure
Local Anesthesia Procedure
Anesthesia Procedure
Local Anesthesia
Local Anesthesia Procedure
C81260
Local Anesthesia Procedure
Newborn Screening
The temporary suppression of sensation at a specific region of the body by pharmacological intervention. This type of anesthesia does not induce unconsciousness in the patient.
Therapeutic or Preventive Procedure
owl:Class
Food Patterns
Nutritional Study
Investigations into the link between food choices and disease. Similar to dietary history.
C16045
Research Activity
Food Patterns
owl:Class
Food Patterns
CL006266
Food Patterns
Psychosocial Studies
C1455743
C15514
Psychosocial Support
owl:Class
Psychosocial Care/Assessment
Psychosocial Assessment and Care
Health Care Activity
Psychosocial Care
Psychosocial Assessment and Care
Psychosocial Assessment and Care
Supportive Care
Psychosocial Assessment
Psychosocial Assessment and Care
The average cell intensity for the sense probe cells used in the grid alignment process.
Corner Plus
Activity
Corner +
owl:Class
C67053
CL371502
Statistical Technique
Corner Plus
Corner P
Corner Plus
Corner Plus
Cohort Study
owl:Class
Cohort Study
Cohort Study
C0009247
Cohort Study
Research Activity
C15208
Longitudinal Study
<def-source>MSH2001</def-source><def-definition>Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.</def-definition>
Immunosuppressive Therapy
C1171324
C70546
owl:Class
B-Cell Depletion Therapy
B-Cell Depletion Therapy
B-Cell Depletion Therapy
B-Lymphocyte Depletion Therapy
B-Cell Depletion Therapy
Therapeutic or Preventive Procedure
C80189
Histamine Measurement
The determination of the amount of histamine present in a sample.
Laboratory Procedure
Histamine Measurement
Histamine Measurement
Protein or Enzyme Type Measurement
Histamine Measurement
owl:Class
Prior Immunotherapy
CL014344
Clinical Attribute
owl:Class
Prior Adjuvant Immunotherapy
Prior Adjuvant Immunotherapy
C16157
Prior Adjuvant Immunotherapy
Prior Adjuvant Immunotherapy
C16065
Cancer Surveillance Research Program
CSRP
Cancer Surveillance Research Program
C1516230
Research Activity
The Surveillance Research Program (SRP) directs a program of cancer surveillance involving the collection and analysis of pertinent data in order to answer key questions about cancer incidence, morbidity, mortality, and cancer-related health status in diverse regions and in general and specific populations of the U.S. defined by sociodemographic measures.
Cancer Surveillance Research Program
Cancer Surveillance Research Program
Surveillance Research Program
owl:Class
Cancer Surveillance Research
owl:Class
Study of Socioeconomic and Demographic Variables
Diagnostic Procedure
Study of Socioeconomic and Demographic Variables
CL035534
Disease Screening
Study of Socioeconomic and Demographic Variables
C62699
Study of Socioeconomic and Demographic Variables
Somatocrinin
Laboratory Procedure
C74862
Hormone Measurement
CL384285
Growth Hormone Releasing Hormone Measurement
Growth Hormone Releasing Hormone Measurement
The determination of the amount of growth hormone releasing hormone present in a sample.
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
GRWHRH
Growth Hormone Releasing Hormone Measurement
Growth Hormone Releasing Hormone Measurement
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
owl:Class
<def-definition>A measurement of the growth hormone releasing hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
Growth Hormone Releasing Hormone
Total-Body Irradiation
Total-Body Irradiation
Total-Body Irradiation
<def-source>NCI-GLOSS</def-source><def-definition>Radiation therapy to the entire body. Usually followed by bone marrow or peripheral stem cell transplantation.</def-definition>
Extensive Radiation
Bone Marrow Ablation
Total-Body Irradiation
total-body irradiation
C0043162
Total Body Irradiation
owl:Class
Therapeutic or Preventive Procedure
Whole-Body Irradiation
<def-source>MSH2001</def-source><def-definition>Irradiation of the whole body with ionizing or non-ionizing radiation. It is applicable to humans or animals but not to microorganisms.</def-definition>
C15350
C64221
Probe Summary Method
owl:Class
Probe Summary Method
Probe Summary Method
CL369124
Probe Summary Method
Statistical Technique
Method for summarizing expression values of all probes in a probe set. Defined in the documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html
Activity
CDISC SDTM Laboratory Test Terminology by Code
Lactate Dehydrogenase to Creatinine Ratio Measurement
Lactate Dehydrogenase to Creatinine Ratio Measurement
Lactate Dehydrogenase/Creatinine
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Name
LDHCREAT
<def-definition>A relative measurement (ratio or percentage) of the lactate dehydrogenase to creatinine in a biological specimen.</def-definition><def-source>CDISC</def-source>
Lactate Dehydrogenase to Creatinine Ratio Measurement
CDISC SDTM Terminology
C79449
The determination of the ratio of lactate dehydrogenase compared to creatinine present in a sample. The measurement may be expressed as a ratio or percentage.
Lactate Dehydrogenase to Creatinine Ratio Measurement
Laboratory Procedure
owl:Class
CDISC SEND Terminology
Urine Protein Measurement
Prior Chemotherapy for Advanced Disease
Clinical Attribute
Prior Chemotherapy for Advanced Disease
CL029114
Prior Chemotherapy for Advanced Disease
Prior Chemotherapy for Advanced Disease
owl:Class
C15450
Prior Chemotherapy
ACANT
Acanthocyte Count
CL384359
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Laboratory Test Terminology by Name
Acanthocyte Count
The determination of the number of acanthocytes present in a sample.
Erythrocyte Count
Acanthocyte Count
CDISC SDTM Terminology
Acanthocytes
owl:Class
<def-source>CDISC</def-source><def-definition>A measurement of the acanthocytes per unit of a biological specimen.</def-definition>
C74699
Laboratory Procedure
Acanthocyte Count
CDISC SEND Terminology
Clinical Data Interchange Standards Consortium Terminology
CDISC
Assembly
CL356238
Assembly
Action
C52474
Instruction Imperative
The act of constructing something.
Assembly
Activity
Assemble
owl:Class
Assembly
Lymph Node Biopsy
C51900
Biopsy
Biopsy of Lymph Node
Lymph Node Biopsy
owl:Class
CL355229
A test in which a lymph node or a piece of a lymph node is removed for examination under a microscope for signs of infection or disease such as cancer.
Lymph Node Biopsy
Diagnostic Procedure
Procedure_Has_Excised_Anatomy some 'Lymph Node'
Lymph Node Biopsy
radiofrequency ablation
Radiofrequency Ablation
Ablation Therapy
Local Therapy
owl:Class
Radiofrequency Ablation
C15666
C0850292
<def-source>NCI-GLOSS</def-source><def-definition>The use of electrodes to heat and destroy abnormal tissue.</def-definition>
A therapeutic procedure to eradicate or reduce small tumors using radiowaves to generate heat. The procedure is performed by the insertion of a thin needle through the skin and into a tumor, which is guided by computed tomography (CT) or ultrasound. Electrical energy delivered through this needle (electrode) heats and destroys the tumor. This therapeutic option is widely utilized by patients that have inoperable cancers, or are unsuitable chemotherapy candidates.
Therapeutic or Preventive Procedure
Radiofrequency Ablation
Radiofrequency Interstitial Ablation
Radiofrequency Ablation
Laparotomy
Diagnostic Procedure
<def-source>NCI-GLOSS</def-source><def-definition>(lap-a-RAH-toe-mee) A surgical incision made in the wall of the abdomen.</def-definition>
C0023038
Therapeutic or Preventive Procedure
owl:Class
Laparotomy
Laparotomy
Laparotomy
laparotomy
Abdominal Surgical Procedure
C15266
Creation of a surgical opening into the abdominal cavity.
Change-Point Analysis
Change-Point Analysis
Statistical Technique
C64211
Change-Point Analysis
Change-Point Analysis
Occupational Activity
owl:Class
CL369265
Methods for determining whether a change has taken place, when it has taken place, the confidence level indicating the likelihood that a change occurred, and the confidence interval indicating when the change occurred.
Circumscribe
Circumscribe
To draw a geometric figure around another figure so that the two are in contact but do not intersect.
Action
Circumscribed
Activity
CL378292
Circumscribe
Circumscribe
owl:Class
C71614
Extraordinary Opportunity: Cancer Communications
Extraordinary Opportunities for Investment
Extraordinary Opportunity: Cancer Communications
Extraordinary Opportunity: Cancer Communications
C16133
Extraordinary Opportunity: Cancer Communications
owl:Class
Research Activity
CL014047
Research Activity
Extraordinary Opportunity: Cancer Genetics
Extraordinary Opportunity: Cancer Genetics
Extraordinary Opportunities for Investment
owl:Class
C16089
Extraordinary Opportunity: Cancer Genetics
CL008664
Extraordinary Opportunity: Cancer Genetics
Laboratory Procedure
Nucleated Erythrocyte to Leukocyte Ratio Measurement
Blood Cell Count Ratio Measurement
The determination of the ratio of nucleated erythrocytes compared to leukocytes present in a sample. The measurement may be expressed as a ratio or percentage.
Nucleated Erythrocyte to Leukocyte Ratio Measurement
C82046
owl:Class
Nucleated Erythrocyte to Leukocyte Ratio Measurement
Nucleated Erythrocyte to Leukocyte Ratio Measurement
owl:Class
Population Based Sampling
Population Based Sampling
Statistical Technique
Population Based Sampling
Population Based Sampling
Quantitative Concept
C53201
CL355784
Draw
Draw
Draw
Represent by making a drawing of, as with pencil, chalk, etc. on a surface; make a mark or lines on a surface.
Draw
Activity
owl:Class
CL357365
C54353
Action
To make according to individual requirements or specifications; to make more personalized or tailored for a specific need.
Activity
Customize
CL384895
Custom
Customize
Customized
Action
Customize
owl:Class
C65167
Customize
Preparative Regimen
Therapeutic or Preventive Procedure
Preparative Regimen
owl:Class
Therapeutic Bone Marrow Suppression
Preparative Regimen
Preparative Regimen
C61155
The chemotherapy and/or radiation given to bone marrow transplant patients prior to transplant to kill diseased cells and/or make space for healthy new marrow and/or suppress the immune system so graft rejection does not occur.
CL364108
<def-source>NCI-GLOSS</def-source><def-definition>(BY-ahp-see) A procedure in which the parts of a mole that are above and just below the surface of the skin are removed with a small blade. There is no need for stitches with this procedure.</def-definition>
Shave Biopsy
Removal skin tissue, for microscopic examination, using a blade oriented in the horizontal plane of the skin surface.
Diagnostic Procedure
Shave Biopsy
owl:Class
shave biopsy
Shave Biopsy
Skin Biopsy
C0184923
Shave Biopsy
C15387
The determination of the number of crenated red blood cells present in a sample.
<def-source>CDISC</def-source><def-definition>A measurement of the Burr cells (erythrocytes characterized by the presence of multiple small, sharp projections evenly distributed across the cell surface) in a biological specimen.</def-definition>
Crenated Cell Measurement
Crenated Cell Measurement
Crenated Cell Measurement
CRENCE
CDISC SDTM Laboratory Test Terminology by Name
CL384384
Clinical Data Interchange Standards Consortium Terminology
CDISC
Echinocytes
Crenated Cells
CDISC SEND Terminology
Laboratory Procedure
Crenated Cell Measurement
Erythrocyte Count
owl:Class
C74703
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Terminology
Palliative Surgery
Palliative Surgery
Palliative Surgery
Palliative Surgery
Therapeutic or Preventive Procedure
C0282282
C17883
Surgical Procedure
Surgery that does not alter the course of a disease, but improves the quality of life.
owl:Class
Partial Small Intestine Resection
Partial Small Bowel Resection
Partial Small Intestine Resection
owl:Class
Partial Small Intestine Resection
C51512
Therapeutic or Preventive Procedure
Partial Small Intestine Resection
Procedure_Has_Partially_Excised_Anatomy only 'Small Intestine'
Small Intestine Resection
CL353589
Partial Small Bowel Excision
Surgical removal of part of the small intestine.
Barbiturate Drug Class Measurement
owl:Class
C75363
Laboratory Procedure
Amobarbital Measurement
Amobarbital Measurement
C0524013
Amobarbital Measurement
The determination of the amount of amobarbital present in a sample.
Amobarbital Measurement
owl:Class
Intercept Vertical Transmission-Perinatal Transmission of HIV
C15808
Intercept Vertical Transmission-Perinatal Transmission of HIV
Research Activity
CL000494
Intercept Vertical Transmission-Perinatal Transmission of HIV
Preventive Intervention
Develop, evaluate, and implement strategies for interrupting vertical transmission of HIV from mother to child and extend our understanding of perinatal transmission and the pathogenesis of early infection (treatment of children will be addressed in other objectives). (Note: The OAR Coordinating Committee on Therapeutics feels scientific objectives 3E through 3G are of equal weight in terms of scientific priorities.)
Intercept Vertical Transmission-Perinatal Transmission of HIV
Therapeutic or Preventive Procedure
Individual Behavior
C63735
Flossing
Flossing
owl:Class
CL366355
Flossing
Health Behavior
Flossing
Using dental floss, a string-like device, to remove plaque and food particles from between the teeth.
Therapeutic or Preventive Procedure
Radiosensitization
radiosensitization
owl:Class
Radiosensitization
CL029163
Radiosensitization
C15464
Radiosensitization
Therapeutic Procedure
<def-source>NCI-GLOSS</def-source><def-definition>The use of a drug that makes tumor cells more sensitive to radiation therapy.</def-definition>
A quantitative measurement of amylase present in a sample.
Laboratory Procedure
Amylase Measurement
Clinical Data Interchange Standards Consortium Terminology
Amylase Measurement
<def-source>CDISC</def-source><def-definition>A measurement of the pancreatic enzyme amylase in a biological specimen.</def-definition>
CDISC SDTM Laboratory Test Terminology by Name
Amylase Measurement
CDISC SDTM Terminology
owl:Class
Protein or Enzyme Type Measurement
Amylase
CDISC SDTM Laboratory Test Terminology by Code
CDISC
AMYLASE
C64434
C0201883
CDISC SEND Terminology
Amylase Measurement
CSMIX
Mixed Casts
Clinical Data Interchange Standards Consortium Terminology
Mixed Cast Count
CL384415
CDISC
Mixed Cast Count
CDISC SDTM Terminology
Laboratory Procedure
Mixed Cast Count
The determination of the number of mixed casts present in a urine sample.
CDISC SDTM Laboratory Test Terminology by Code
Urine Sediment Analysis Measurement
CDISC SDTM Laboratory Test Terminology by Name
owl:Class
Mixed Cast Count
CDISC SEND Terminology
C74771
<def-source>CDISC</def-source><def-definition>A measurement of the mixed (the cast contains a mixture of cell types) casts present in a urine specimen.</def-definition>
Basophils/Leukocytes
Basophil to Leukocyte Ratio
CDISC SDTM Laboratory Test Terminology by Name
C64471
Clinical Data Interchange Standards Consortium Terminology
Basophil to Leukocyte Ratio
The determination of the ratio of basophils to leukocytes in a blood sample. The measurement may be expressed as a ratio or percentage.
Basophil to Leukocyte Ratio
CDISC SDTM Laboratory Test Terminology by Code
Blood Cell Count Ratio Measurement
Laboratory Procedure
CDISC SDTM Terminology
owl:Class
CDISC
CL370128
Basophil to Leukocyte Ratio
<def-definition>A relative measurement (ratio or percentage) of the basophils to leukocytes in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SEND Terminology
BASOLE
Preventive Intervention
C15669
Cancer Prevention
owl:Class
All methods of preventing cancer including limit of exposure to carcinogens and infectious agents, diet, education, etc
CL034431
Cancer Prevention
Cancer Prevention
Therapeutic or Preventive Procedure
Cancer Prevention
CDISC SDTM Laboratory Test Terminology by Code
Laboratory Procedure
CDISC SDTM Terminology
<def-source>CDISC</def-source><def-definition>The percentage of a whole blood specimen that is composed of red blood cells (erythrocytes).</def-definition>
CDISC SDTM Laboratory Test Terminology by Name
C64796
Hematology Test
C0018935
Hematocrit Measurement
Clinical Data Interchange Standards Consortium Terminology
Hematocrit Measurement
CDISC SEND Terminology
owl:Class
HCT
A measure of the volume of red blood cells expressed as a percentage of the total blood volume. Normal in males is 43-49%, in females 37-43%.
Hematocrit
Hematocrit Measurement
CDISC
Hematocrit Measurement
Include
Include
C0332257
Activity
Include
Add as part of something else; put in as part of a set, group, or category.
Include
C74521
owl:Class
Action
owl:Class
CDISC SEND Terminology
Laboratory Procedure
Cannabinoid Drug Class Measurement
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Terminology
CDISC SDTM Laboratory Test Terminology by Name
The determination of the amount of cannabinoid class agents present in a sample.
Cannabinoid Drug Class Measurement
<def-source>CDISC</def-source><def-definition>A measurement of any cannabinoid class drug present in a biological specimen.</def-definition>
CNS Depressant Drug Measurement
CANNAB
Cannabinoids
CDISC
Cannabinoid Drug Class Measurement
Cannabinoid Drug Class Measurement
C0202349
CDISC SDTM Laboratory Test Terminology by Code
C74689
Butcher
Action
C53477
CL357373
owl:Class
Butchered
Activity
Butcher
Butcher
Butcher
Butchering
To slaughter or prepare an animal for market.
A quantitative measurement of the amount of sodium present in a sample.
Electrolyte Measurement
CDISC SEND Terminology
CDISC
SODIUM
C64809
Sodium Measurement
owl:Class
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
Sodium Measurement
CDISC SDTM Terminology
Laboratory Procedure
<def-source>CDISC</def-source><def-definition>A measurement of the sodium in a biological specimen.</def-definition>
Sodium Measurement
Sodium Measurement
C0337443
Sodium
CDISC SDTM Laboratory Test Terminology by Name
owl:Class
Procedure_Has_Excised_Anatomy only 'Thyroid Gland'
C51648
Surgery to remover part or all of the thyroid gland.
Thyroidectomy
Thyroidectomy
C0040145
Therapeutic or Preventive Procedure
Thyroidectomy
Thyroidectomy
Head and Neck Surgery
owl:Class
Excision of the apex of the petrous portion of the temporal bone.
Apicectomy
FDA
Excision of Bone
Apicectomy
Procedure_Has_Excised_Anatomy only 'Temporal Bone'
Apicectomy
Patient Problem Codes FDA CDRH
Patient Code (Appendix B)
CL354378
Head and Neck Surgery
Therapeutic or Preventive Procedure
Apicectomy
C50824
Orthopedic Surgical Procedure
C21009
Discectomy
Procedure_Has_Excised_Anatomy only 'Intervertebral Disc'
owl:Class
Discectomy
C0206078
Discectomy
Surgical excision of an intervertebral disc. Often performed for pain relief.
Discectomy
Therapeutic or Preventive Procedure
<def-source>NCI-GLOSS</def-source><def-definition>Care that prevents or relieves the symptoms of disease or the side effects of treatment. Palliative care does not alter the course of a disease but can improve the quality of life. It attempts to meet the physical, emotional, spiritual, and practical needs of patients by helping to relieve pain, depression, or other problems.</def-definition>
The patient- and family-centered active holistic care of patients with advanced, progressive disease. Essential components of palliative care are: pain and symptom control, communication regarding treatment and alternatives, prognosis, and available services, rehabilitation services, care that addresses treatment and palliative concerns, intellectual, emotional, social, and spiritual needs, terminal care, support in bereavement. The goal of palliative care is an achievement of the best quality of life for patients and their families.
Symptom Management
owl:Class
Palliative Therapy
Palliative Care
symptom management
C0030231
Comfort Care
comfort care
Supportive Care
palliative care
Therapeutic or Preventive Procedure
Palliative Therapy
Symptoms Management
palliative therapy
Palliative Therapy
C15292
Palliative Therapy
Palliative Treatment
TCID50
Tissue Culture Infection Dose
Tissue Culture Infection Dose 50
Structured Product Labeling Potency Terminology
A quantity of a pathogen required to infect 50% of the tissue cultures inoculated.
FDA
UCUM Terminology
Conceptual Entity
Tissue Culture Infection Dose 50
Potency (C-DRG-00501)
UCUM
owl:Class
C67450
Tissue Culture Infection Dose 50
Tissue Culture Infection Dose 50
TCID 50
{TCID50}
TISSUE CULTURE INFECTIOUS DOSE 50%
CL371804
[TCID_50]
tissue culture infection dose 50
Procedure_Has_Target_Anatomy only Joint
Arthroplasty
Arthroplasty
Orthopedic Surgical Procedure
C51691
Arthroplasty
owl:Class
Arthroplasty
C0003893
Therapeutic or Preventive Procedure
Surgical reconstruction or replacement of all or part of a malformed, diseased, degenerated, or otherwise damaged joint.
Clinical Testing
Clinical Sensitivity
Clinical Sensitivity
CL093278
Clinical Sensitivity
Qualitative Concept
owl:Class
Clinical Sensitivity
C16234
owl:Class
C74780
Adrenocorticotropic Hormone Measurement
Hormone Measurement
Adrenocorticotropic Hormone Measurement
CDISC
CDISC SEND Terminology
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Name
Adrenocorticotropic Hormone Measurement
Adrenocorticotropic Hormone Measurement
C0201835
ACTH
CDISC SDTM Terminology
The determination of the amount of adrenocorticotropic hormone present in a sample.
CDISC SDTM Laboratory Test Terminology by Code
Adrenocorticotropic Hormone
<def-source>CDISC</def-source><def-definition>A measurement of the adrenocorticotropic hormone in a biological specimen.</def-definition>
Laboratory Procedure
C25214
Systematic, objective appraisal of the significance, effectiveness, and impact of activities or condition according to specified objectives and criteria.
Evaluation
Activity
C0220825
Evaluated
owl:Class
Action
Evaluation
Evaluation
Evaluate
Evaluation
Alprazolam Measurement
owl:Class
Alprazolam Measurement
C75370
Alprazolam Measurement
Alprazolam Measurement
Benzodiazepine Measurement
Laboratory Procedure
The determination of the amount of alprazolam present in a sample.
C0524002
Socializing
Socialize
Socializing
Socializing
owl:Class
Taking part in social activities; interacting with others.
Physical Activity
Socializing
Daily or Recreational Activity
C81007
Research Activity
Tryptic Digestion
Tryptic Digestion
Trypsin Digestion
A technique for proteolysis of proteins into peptides at lysine or arginine by treatment with the pancreatic enzyme trypsin.
owl:Class
Tryptic Digestion
Tryptic Digestion
Protein Digestion
C68835
CL374366
The determination of the amount of secretin hormone present in a sample.
Secretin
CDISC SDTM Laboratory Test Terminology by Name
Hormone Measurement
CDISC SDTM Terminology
Secretin Measurement
Laboratory Procedure
C0523887
Secretin Measurement
<def-definition>A measurement of the secretin hormone in a biological specimen.</def-definition><def-source>CDISC</def-source>
owl:Class
Clinical Data Interchange Standards Consortium Terminology
Secretin Measurement
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Code
C74871
Secretin Measurement
SECRETIN
Laboratory Procedure
owl:Class
C80180
F2 Isoprostane Measurement
Urine Chemistry Measurement
F2 Isoprostane Measurement
F2 Isoprostane Measurement
The determination of the amount of F2 isoprostane present in a urine sample.
F2 Isoprostane Measurement
Amphetamine Drug Class Measurement
Laboratory Procedure
C75349
CL384548
The determination of the amount of tenamfetamine (MDA) present in a sample.
Tenamfetamine Measurement
Tenamfetamine Measurement
owl:Class
Tenamfetamine Measurement
Tenamfetamine Measurement
owl:Class
Nanoparticle Application
Nanoparticle Application
CL364923
Nanoparticle Application
Nanoparticle Application
The utilization of small (&lt;100 nm), stable particles in a variety of technologies. Based on an understanding of chemical, biological and physical phenomena at the nanoscale level, processes are employed to create new nanoparticle technologies.
C62309
Activity
Research Technique
Vitamin Measurement
owl:Class
Vitamin B2 Measurement
Vitamin B2 Measurement
Laboratory Procedure
The determination of the amount of Vitamin B2 present in a sample.
Clinical Data Interchange Standards Consortium Terminology
Vitamin B2 Measurement
CDISC SDTM Laboratory Test Terminology by Code
VITB2
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
Vitamin B2
C74898
<def-definition>A measurement of the riboflavin in a biological specimen.</def-definition><def-source>CDISC</def-source>
Vitamin B2 Measurement
CDISC SDTM Terminology
Riboflavin
CL384439
biological therapy
Biological Therapy
owl:Class
A form of treatment that implies the administration of substances which produce a biological reaction in the organism thus enhancing or restoring the host immune response, modifying the behavior of cancer cells, blocking the pathways of cell neoplastic transformation and tumor ability to metastasize, or facilitating the repair of cells damaged by aggressive forms of cancer treatment. It includes the use of sera, antitoxins, vaccines, genes, cells, tissues, and organs.
Biotherapy
biotherapy
Biological Therapy
Biologics Therapies
C15187
Biological Therapy
Biological Therapy
Therapeutic Procedure
<def-source>NCI-GLOSS</def-source><def-definition>(by-o-LAHJ-i-kul...)Treatment to stimulate or restore the ability of the immune system to fight infections and other diseases. Also used to lessen side effects that may be caused by some cancer treatments.</def-definition>
Therapeutic or Preventive Procedure
C0005527
Biological Response Modifier Therapy
Biological Response Modifiers Therapy
Flow Cytometry
C0016263
A technique for counting, examining and sorting microscopic particles suspended in a stream of fluid.
Flow Cytometry
Laboratory Procedure
Immunology Test
Flow Cytometry
Flow Cytometry
C16585
owl:Class
CL366201
Endocrine Drug Therapy
Endocrine Therapy
C63475
owl:Class
Endocrine Drug Therapy
Therapeutic or Preventive Procedure
Endocrine Drug Therapy
Endocrine Drug Therapy
Total Abdominal Hysterectomy with Bilateral Salpingo-Oophorectomy
Total Abdominal Hysterectomy
Procedure_Has_Completely_Excised_Anatomy only 'Left Fallopian Tube'
Procedure_Has_Completely_Excised_Anatomy only 'Right Ovary'
CL354279
Total Abdominal Hysterectomy with Bilateral Salpingo-Oophorectomy
Total Abdominal Hysterectomy with Bilateral Salpingo-Oophorectomy
Therapeutic or Preventive Procedure
Total Abdominal Hysterectomy with Bilateral Salpingo-Oophorectomy
Procedure_Has_Completely_Excised_Anatomy only 'Left Ovary'
owl:Class
Procedure_Has_Completely_Excised_Anatomy only 'Right Fallopian Tube'
C51761
Surgical removal of all of the uterus, and the right and left fallopian tubes, and the right and left ovaries.
Salpingo-Oophorectomy
Use of optical coherence tomography to capture ulta-high resolution images of tissue surfaces which can be used to identify cancerous legions.
CL028311
Diagnostic Procedure
Optical Biopsy
Imaging Technique
C20827
Optical Biopsy
owl:Class
Optical Biopsy
Optical Biopsy
CDISC SDTM Laboratory Test Terminology by Code
Interleukin 3 Measurement
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Name
Clinical Data Interchange Standards Consortium Terminology
INTLK3
The determination of the amount of interleukin 3 present in a sample.
owl:Class
CL384313
CDISC SEND Terminology
Interleukin 3 Measurement
CDISC SDTM Terminology
C74827
Interleukin 3
Cytokine Measurement
<def-definition>A measurement of the interleukin 3 in a biological specimen.</def-definition><def-source>CDISC</def-source>
Interleukin 3 Measurement
Interleukin 3 Measurement
C81957
owl:Class
Reg upon Act Normal T-cell Exprd Secrtd Measurement
Reg upon Act Normal T-cell Exprd Secrtd Measurement
The determination of the amount of the RANTES (regulated on activation, normally, T-cell expressed, and secreted) chemokine present in a sample.
Reg upon Act Normal T-cell Exprd Secrtd Measurement
Reg upon Act Normal T-cell Exprd Secrtd Measurement
Chemokine Measurement
Surgical Procedure by Method
Limb Salvage Procedure
Limb Salvage Procedures
CL005581
owl:Class
Limb Salvage Procedure
Limb Salvage Procedure
Limb Salvage Procedure
C16042
Methods to avoid amputation of an arm or leg
Therapeutic or Preventive Procedure
ANTIDPRS
CL384370
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
owl:Class
Antidepressants
Antidepressant Measurement
CNS Affecting Drug Measurement
<def-definition>A measurement of any antidepressant class drug present in a biological specimen.</def-definition><def-source>CDISC</def-source>
Laboratory Procedure
C74691
Antidepressant Measurement
Antidepressant Measurement
CDISC SDTM Laboratory Test Terminology by Name
CDISC SEND Terminology
CDISC SDTM Terminology
Antidepressant Measurement
The determination of the amount of antidepressant class drug present in a sample.
Biological Testing
Laboratory Procedure
C18649
Biological Testing
Biological Testing
Testing performed to determine the effects of substances upon living organisms.
CL102890
Mixed Category Laboratory Procedure
Biological Testing
owl:Class
Glucose to Creatinine Ratio Measurement
<def-definition>A relative measurement (ratio or percentage) of the glucose to creatinine in a biological specimen.</def-definition><def-source>CDISC</def-source>
Glucose to Creatinine Ratio Measurement
The determination of the ratio of glucose compared to creatinine present in a sample. The measurement may be expressed as a ratio or percentage.
C79447
CDISC SEND Terminology
Glucose to Creatinine Ratio Measurement
Glucose/Creatinine
Urine Protein Measurement
Glucose to Creatinine Ratio Measurement
CDISC SDTM Terminology
Clinical Data Interchange Standards Consortium Terminology
GLUCCRT
Laboratory Procedure
CDISC SDTM Laboratory Test Terminology by Code
owl:Class
CDISC SDTM Laboratory Test Terminology by Name
Hemoglobin A2 to Total Hemoglobin Ratio Measurement
Hemoglobin A2 to Total Hemoglobin Ratio Measurement
Hemoglobin A2 to Total Hemoglobin Ratio Measurement
Laboratory Procedure
Hemoglobin Measurement
Percent Hemoglobin A2
The determination of the ratio of Hemoglobin A2 compared to total Hemoglobin present in a sample. The measurement may be expressed as a ratio or percentage.
Hemoglobin A2 to Total Hemoglobin Ratio Measurement
C81277
owl:Class
Newborn Screening
CL355284
C51675
Needle Biopsy of Liver
Needle Biopsy
owl:Class
Needle Biopsy of Liver
Liver Biopsy
Needle Biopsy of Liver
Removal of tissue from the liver for microscopic examination, using a needle.
Needle Biopsy of Liver
Diagnostic Procedure
Glossectomy
Total Excision of Tongue
Surgery involving complete excision of the tongue.
Procedure_Has_Completely_Excised_Anatomy only Tongue
Total Excision of Tongue
Therapeutic or Preventive Procedure
Total Excision of Tongue
CL354834
Total Glossectomy
Total Excision of Tongue
C51598
owl:Class
Dental Procedure
Therapeutic or Preventive Procedure
owl:Class
C52570
CL355681
Acid Etching
Acid Etching
Acid Etching
Acid Etching
The use of an acid to condition tooth structure, resulting in a superficial demineralization.
C65123
Do Not Chew
Do Not Chew
Instruction Imperative
owl:Class
C0566342
Activity
Do Not Chew
Do Not Chew
Percutaneous Neuromodulation Therapy
Percutaneous Neuromodulation Therapy
PNT
CL100598
A minimally invasive form of electroanalgesia, similar to PENS but using deeper needles depths, that is used to treat intractable chronic lower back pain, cancer pain, and other painful disorders. (from White, Li, and Chiu)
Electroanalgesia
Therapeutic or Preventive Procedure
owl:Class
Percutaneous Neuromodulation Therapy
Percutaneous Neuromodulation Therapy
C21027
Antifungal Therapy
Antifungal Therapy
Therapeutic or Preventive Procedure
owl:Class
Antifungal Therapy
Antifungal Therapy
CL031924
Treatment of Fungal Infectious Disease
C15704
Infection Prophylaxis and Management
Drug treatment to destroy or inhibit the growth or multiplication of fungi.
C0029164
Oral Hygiene
Personal Behavior
Oral Hygiene
Oral Hygiene
Dental Hygiene
owl:Class
C60725
The practice of keeping the mouth, teeth, and gums clean and healthy to prevent disease, as by regular brushing and flossing and visits to a dentist.
Health Care Activity
Oral Hygiene
CDISC SEND Terminology
Laboratory Procedure
<def-definition>A measurement of the insulin-like growth factor-1 in a biological specimen.</def-definition><def-source>CDISC</def-source>
IGF1
CDISC SDTM Laboratory Test Terminology by Name
Insulin Like Growth Factor-1 Measurement
CDISC SDTM Laboratory Test Terminology by Code
owl:Class
Insulin Like Growth Factor-1 Measurement
Hormone Measurement
CDISC SDTM Terminology
C0202220
C74864
Clinical Data Interchange Standards Consortium Terminology
The determination of the amount of insulin-like growth factor-1 present in a sample.
Insulin Like Growth Factor-1 Measurement
Insulin-like Growth Factor-1
Insulin Like Growth Factor-1 Measurement
owl:Class
CL014057
IMRT
Intensity-Modulated Radiation Therapy
Intensity-Modulated Radiation Therapy
C16135
Intensity-Modulated Radiation Therapy
An advanced form of 3-Dimensional Conformal Radiation Therapy that involves the use of varying intensities of small radiation beams to produce dosage distributions that are more precise than those possible with 3-D CRT.
Intensity-Modulated Radiation Therapy
Intensity-Modulated Radiotherapy
Therapeutic or Preventive Procedure
Intensity Modulated RT
3-Dimensional Conformal Radiation Therapy
Use of a DNA or RNA probe to detect the presence of complementary sequences in chromosomes, cells, or tissues
Laboratory Procedure
in situ Hybridization
Genetics, in situ Hybridization
<def-source>MSH2001</def-source><def-definition>A technique that localizes specific nucleic acid sequences within intact chromosomes, eukaryotic cells, or bacterial cells through the use of specific nucleic acid-labeled probes.</def-definition>
in situ Hybridization
C17562
C0162788
Molecular Biology Research Technique
Nucleic Acid Hybridization
in situ Hybridization
owl:Class
in situ Hybridization
A process of active consideration of potential subjects for enrollment in a trial.
Trial Screening
Trial Screening
CL343304
C48262
Research Activity
owl:Class
Trial Screening
Trial Screening
Disease Screening
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Terminology
CDISC
CL370308
C64827
CDISC SDTM Laboratory Test Terminology by Code
owl:Class
CDISC SDTM Laboratory Test Terminology by Name
Neutrophil to Leukocyte Ratio
<def-definition>A relative measurement (ratio or percentage) of the neutrophils to leukocytes in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SEND Terminology
Blood Cell Count Ratio Measurement
Neutrophil to Leukocyte Ratio
Neutrophils/Leukocytes
Neutrophil to Leukocyte Ratio
Prior to ingestion of food.
NEUTLE
Laboratory Procedure
Neutrophil to Leukocyte Ratio
C15565
owl:Class
Prior Hormone Therapy
Prior Adjuvant Endocrine/Hormonal Therapy
Clinical Attribute
CL030549
Prior Adjuvant Endocrine/Hormonal Therapy
Prior Adjuvant Endocrine/Hormonal Therapy
Prior Adjuvant Endocrine/Hormonal Therapy
stereotaxic radiosurgery
Stereotactic Radiosurgery
owl:Class
Stereotactic Radiosurgery
Stereotactic Radiosurgery
<def-source>NCI-GLOSS</def-source><def-definition>(STAIR-ee-o-TAK-tik...) A radiation therapy technique involving a rigid head frame that is attached to the skull; high-dose radiation is administered through openings in the head frame to the tumor while decreasing the amount of radiation given to normal brain tissue. This procedure does not involve surgery.</def-definition>
Stereotactic Radiosurgery
C15358
stereotactic radiosurgery
Radiosurgery
C0085203
Therapeutic or Preventive Procedure
Molecular Diagnostic Method
Molecular Diagnostic Method
C0949688
Diagnostic Procedure
Molecular Diagnostic Method
Laboratory Procedure
Molecular Analysis
Methods for diagnosis or monitoring of disease predisposition by translation and validation of molecular discoveries in medicine into the clinical diagnostic setting.
C18194
Molecular Diagnostic Method
owl:Class
Chlordiazepoxide Measurement
Laboratory Procedure
Chlordiazepoxide Measurement
Benzodiazepine Measurement
The determination of the amount of chlordiazepoxide present in a sample.
owl:Class
Chlordiazepoxide Measurement
C0202356
C75371
Chlordiazepoxide Measurement
owl:Class
The determination of the ratio of metamyelocytes compared to leukocytes present in a sample. The measurement may be expressed as a ratio or percentage.
CDISC
CDISC SDTM Laboratory Test Terminology by Name
CL384328
Metamyelocyte to Leukocyte Ratio Measurement
C74645
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Terminology
<def-source>CDISC</def-source><def-definition>A relative measurement (ratio or percentage) of the metamyelocytes (small, myelocytic neutrophils with an indented nucleus) to all leukocytes in a biological specimen.</def-definition>
Metamyelocyte to Leukocyte Ratio Measurement
Metamyelocytes/Leukocytes
Metamyelocyte to Leukocyte Ratio Measurement
Blood Cell Count Ratio Measurement
METAMYLE
Metamyelocyte to Leukocyte Ratio Measurement
CDISC SEND Terminology
Laboratory Procedure
Clinical Data Interchange Standards Consortium Terminology
C0203126
Cystography
Cystography
C38049
Cystography
Cystography
owl:Class
Radiography
A radiographic procedure to obtain an image of the urinary bladder by filling the bladder with contrast medium.
Diagnostic Procedure
C15411
C0199974
Cytokine Therapy
owl:Class
Cytokine Therapy
Therapeutic or Preventive Procedure
Cytokine Therapy
Immunotherapy
Cytokine Therapy
Embolectomy
Cardiovascular Surgical Procedure
Procedure_Has_Target_Anatomy only Artery
Therapeutic or Preventive Procedure
Surgery performed with the purpose of removing an embolus.
Embolectomy
owl:Class
CL355091
Procedure_Has_Target_Anatomy only Blood
Embolectomy
Embolectomy
C52001
Genetic Modification
Research Activity
owl:Class
CL100929
Organism Modification
Techniques used for deliberately altering the genetic material of an organism in order to make them capable of making new substances or performing new or different functions.
Organism Modification
Research Activity
Organism Modification
C22489
Organism Modification
Organism Modification
Research Activity
Randomized Clinical Trial
owl:Class
Randomized Clinical Trials
C15417
Randomized Clinical Trial
Randomized Clinical Trial
<def-source>NCI-GLOSS</def-source><def-definition>A study in which the participants are assigned by chance to separate groups that compare different treatments; neither the researchers nor the participants can choose which group. Using chance to assign people to groups means that the groups will be similar and that the treatments they receive can be compared objectively. At the time of the trial, it is not known which treatment is best. It is the patient's choice to be in a randomized trial.</def-definition>
C0206034
Clinical Study by Design
Randomized Clinical Trial
randomized clinical trial
CL003285
Cooperative Trial in Diagnostic Imaging
C15947
A single national Network of investigators that will perform multi-institutional clinical trials in diagnostic imaging related to cancer. The Network will have the capability to conduct a broad spectrum of clinical trials in imaging. This Network will generate new trials in areas of high scientific opportunity. The Network will consist of a Headquarters office that coordinates operations, a Biostatistics and Data Management Center (BDMC), and a number of participating institutions in which the studies are performed. Participating institutions will be selected by the Network's scientific leadership for their ability to contribute to the particular trials in the Network's research repertoire.
owl:Class
Cooperative Trial in Diagnostic Imaging
Cooperative Trial in Diagnostic Imaging
Diagnostic Imaging Program
Cooperative Trial in Diagnostic Imaging
Research Activity
Activity
Rated
C1521828
C77538
Rating
Rate
Rating
Rating
owl:Class
Action
Rating
The act of ascertaining or fixing the value or worth of something.
Alveoloplasty
Surgical preparation of the alveolar ridges, commonly used for the reception of dentures.
Alveoloplasty
Dental Procedure
owl:Class
Alveoloplasty
C0002393
Therapeutic or Preventive Procedure
Alveoloplasty
C63753
A method of treating disease, esp. psychic disorders, by mental rather than pharmacological means (e.g., suggestion, re-education, hypnotism, and psychoanalysis). (Taber's)
Psychotherapy
Psychotherapy
Therapeutic Procedure
<def-source>CSP2000</def-source><def-definition>any form of treatment for mental illness or emotional disturbance primarily by communicating with a trained individual.</def-definition>
Therapeutic or Preventive Procedure
Psychotherapy
<def-source>MSH2001</def-source><def-definition>A generic term for the treatment of mental illness or emotional disturbances primarily by verbal or nonverbal communication.</def-definition>
owl:Class
C0033968
Psychotherapy
C15308
Apply
Putting something to a special use or purpose; the act of laying on a substance or preparation.
Application
APPLICATION
Application
UCUM
UCUM Terminology
owl:Class
Action
C25397
application
{Application}
Application
Activity
Applied
Application
CL025718
Long Term Survivorship
The situation where a person has survived a disease for years
Long Term Survivorship
C19312
Long Term Survivorship
Survival
owl:Class
Long Term Survivorship
CL003658
Finding
Decalcification
Decalcification
Laboratory Procedure
C51943
Tissue Processing Technique
Decalcification
Decalcification
owl:Class
CL353873
Tomography
Diagnostic Procedure
Tomography
C38093
Imaging Technique
C0040395
Tomography
Imaging by sections or sectioning.
owl:Class
Tomography
C16341
Bioassay
owl:Class
Assay
Bioassay
A laboratory test or analysis of the biological activity of a substance performed by studying its effect on an organism or in a test tube under controlled conditions.
Assay
Laboratory Procedure
C0005507
Bioassay
Bioassay
C0010408
cryosurgery
Cryosurgery
Surgical Procedure by Method
The removal of a body part, pathway, or function by freezing the desired entity. The procedure is performed using small cryogenic probes during surgery, and has recently been applied to solitary sporadic renal tumor lesions.
<def-source>NCI-GLOSS</def-source><def-definition>(KRYE-o-SIR-jer-ee) Treatment performed with an instrument that freezes and destroys abnormal tissues.</def-definition>
Cryosurgery
Cryosurgery
Ablation Therapy
Therapeutic or Preventive Procedure
owl:Class
Cryoablation
The use of extreme cold (usually liquid nitrogen) to destroy unwanted tissue (e.g., warts, cataracts, or skin cancers).
Therapeutic Surgical Procedure
Cryosurgery
C15215
<def-source>MSH2001</def-source><def-definition>The use of freezing as a special surgical technique to destroy or excise tissue.</def-definition>
owl:Class
Chromosome Rearrangement Detection
Chromosome Rearrangement Detection
Molecular Biology Research Technique
Chromosome Rearrangement Detection
Chromosome Rearrangement Detection
C18697
Staining of metaphase spreads for crossovers, inversions, and translocations. Includes karyotyping, fluorescence in situ hybridization, and chromosome painting. (NCI/OSP)
Genetic Technique
CL000211
Regulatory Assessment
Safety Issue
owl:Class
Safety Issue
SAFETY ISSUE
Safety Issue
Safety Issue
Intellectual Product
C82461
Clinical Data Interchange Standards Consortium Terminology
Leukocyte Count
CDISC SDTM Terminology
C64823
MONO
CDISC
Monocytes
CDISC SDTM Laboratory Test Terminology by Name
Monocyte Count
Monocyte Count
Monocyte Count
Monocyte Count
C0200637
Laboratory Procedure
CDISC SEND Terminology
CDISC SDTM Laboratory Test Terminology by Code
The determination of the number of monocytes in a blood sample.
<def-definition>A measurement of the monocytes per unit of a biological specimen.</def-definition><def-source>CDISC</def-source>
owl:Class
Method for identifying invariant set normalization baseline using psuedo median expression values. Defined in the documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html.
Pseudo Median Baseline Removal Method
Pseudo Median Baseline Removal Method
Pseudo Median Baseline Removal Method
owl:Class
CL369339
Baseline Removal Method
Pseudo Median Baseline Removal Method
C64241
Activity
Technology Assessment
Occupational Activity
C15335
Research Activity
Technology Assessment
Technology Assessment
C0039422
Technology assessment (TA) arose in the mid-1960s from an appreciation of the critical role of technology in modern society and its potential for unintended, and sometimes harmful, consequences. TA was conceived as a way to identify the desirable first-order, intended effects of technologies as well as the higher-order, unintended social, economic and environmental effects. TA methodology draws upon a variety of analytical, evaluative and planning techniques. Among these are systems analysis, cost-benefit analysis, consensus methods (e.g., Delphi method), engineering feasibility studies, clinical trials, market research, technological forecasting, and others. TA practitioners and policy makers recognized that TA is evolving, flexible, and should be tailored to the task (Brooks and Bowers 1970 and U.S. Congress, Office of Technology Assessment 1977).
owl:Class
Technology Assessment
Clinical Attribute
Prior LHRH Agonist Therapy
Releasing Hormone Agonist Therapy
C15503
Prior LHRH Agonist Therapy
Prior LHRH Agonist Therapy
owl:Class
Prior LHRH Agonist Therapy
CL029669
C15446
Adjuvant Trials
Adjuvant Trial
CL029011
Adjuvant Study
Adjuvant Study
Research Activity
Adjuvant Study
A study performed secondary to and in support of a primary or base study in order to support, enhance, or expand upon its results or findings.
Clinical Trial
Adjuvant Study
Adjuvant Protocol
owl:Class
Quantitative Concept
Transition Zone PSA Density
Transition Zone PSA Density
CL014595
The ratio of serum PSA to transition zone volume. Takes into account the size of the prostate in determining the significance of an elevated PSA level.
Transition Zone PSA Density
owl:Class
Transition Zone Prostate Specific Antigen Density
Transition Zone PSA Density
Prostate Specific Antigen Measurement
C20043
<def-definition>Describes a mathematical measure of difference between groups. The difference is said to be statistically significant if it is greater than what might be expected to happen by chance alone.</def-definition><def-source>NCI-GLOSS</def-source>
Statistical Significance
CL384928
Statistical Technique
Statistical Significance
Qualitative Concept
Statistical Significance
Statistically Significant
C61040
statistically significant
Statistical Significance
owl:Class
Significance
In statistics, a number that expresses the probability that the result of a given experiment or study could have occurred purely by chance. This number can be a margin of error or it can indicate a confidence level.
C82091
owl:Class
Any orthodontic procedure that is done as part of another dental procedure.
Adjunctive Orthodontic Procedure
Therapeutic or Preventive Procedure
Adjunctive Orthodontic Procedure
Orthodontic Treatment
Adjunctive Orthodontic Procedure
Adjunctive Orthodontic Procedure
Adjunctive
A type of culture in which cells grow as a monolayer that is attached to the culture substrate.
Monolayer culture
Laboratory Procedure
C20216
Adherent Culture
Cell Culture
Adherent Culture
Adherent Culture
owl:Class
Adherent Culture
CL026134
A form of therapy that involves systems using "subtle energy" fields in and around the body for medical/therapeutic purposes. Examples include Therapeutic Touch, Reiki, Huna, laying-on-of-hands, external Qi-Gong, Healing Science, Healing touch, Natural healing, Specific Human Energy Nexus (SHEN), and Bio-Relaxation.
Therapeutic or Preventive Procedure
Energy Therapy
Biofield Therapy
Biofield Therapy
owl:Class
C15910
Biofields
CL002443
Biofield Therapy
Biofield Medicine
Biofield Therapy
Anti-DNA Antibody Measurement
Immunology Test
The determination of the amount of anti-DNA antibodies present in a sample.
Anti-DNA Antibody Measurement
C81973
Anti-DNA Antibody Measurement
Anti-DNA Antibody Measurement
owl:Class
Peripheral Stem Cell Support
Peripheral Blood Stem Cell Transplantation
A method of replacing blood-forming cells destroyed by cancer treatment. Certain cells (stem cells) in the blood that are similar to those in the bone marrow are removed from the patient's blood before treatment. The cells are given back to the patient after treatment.
peripheral stem cell transplantation
Peripheral Blood Stem Cell Transplantation
Similar to bone marrow transplantation, peripheral stem cell transplantation is a method of replacing the blood-forming cells lost due to high-dose chemotherapy, and possibly radiation therapy, used to destroy leukemia cells. Certain immature circulating blood cells, similar to stem cells in the bone marrow, are removed before treatment. The cells are then given to the patient after treatment to help the bone marrow recover and continue producing healthy blood cells. Transplantation may be autologous (the patient's own blood cells are used), allogeneic (blood cells are donated by someone else), or syngeneic (blood cells are donated by an identical twin). The method is also called peripheral stem cell support.
Peripheral Blood Stem Cell Transplantation
C15430
Peripheral Stem Cell Transplantation
Hematopoietic Stem Cell Transplantation
peripheral stem cell support
A procedure that is similar to bone marrow transplantation. Doctors remove healthy immature cells (stem cells) from a patient's blood and store them before the patient receives high-dose chemotherapy and possibly radiation therapy to destroy the leukemia cells. The stem cells are then returned to the patient, where they can produce new blood cells to replace cells destroyed by the treatment.
<def-source>NCI-GLOSS</def-source><def-definition>(per-IF-er-al) A method of replacing blood-forming cells destroyed by cancer treatment. Immature blood cells (stem cells) in the circulating blood that are similar to those in the bone marrow are given after treatment to help the bone marrow recover and continue producing healthy blood cells. Transplantation may be autologous (an individual's own blood cells saved earlier), allogeneic (blood cells donated by someone else), or syngeneic (blood cells donated by an identical twin).</def-definition>
Peripheral Blood Progenitor Cell Transplantation
C0242602
Peripheral Blood Stem Cell Transplantation
Therapeutic or Preventive Procedure
PBPC transplantation
owl:Class
owl:Class
Dietary Intervention
Therapeutic Dietary Intervention
Therapeutic Dietary Intervention
Therapeutic or Preventive Procedure
Therapeutic Dietary Intervention
C64892
CL370554
Nutritional Therapy
Therapeutic Dietary Intervention
<def-definition>A measurement of the interleukin 8 in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SDTM Laboratory Test Terminology by Name
CDISC SDTM Terminology
Laboratory Procedure
Interleukin 8
CDISC SDTM Laboratory Test Terminology by Code
INTLK8
CL384318
Cytokine Measurement
Interleukin 8 Measurement
Interleukin 8 Measurement
C74836
Interleukin 8 Measurement
owl:Class
Clinical Data Interchange Standards Consortium Terminology
The determination of the amount of interleukin 8 present in a sample.
Interleukin 8 Measurement
CDISC SEND Terminology
C50834
Closed Capsulotomy
Patient Problem Codes FDA CDRH
Closed Capsulotomy
Therapeutic Procedure
Closed Capsulotomy
Therapeutic or Preventive Procedure
Patient Code (Appendix B)
FDA
CL355037
Closed Capsulotomy
owl:Class
Unadjusted Incidence Rate
CL356377
Incidence Rate
C53351
Quantitative Concept
owl:Class
Unadjusted Incidence Rate
Unadjusted Incidence Rate
Unadjusted Incidence Rate
Preventive Community Trial
owl:Class
C39497
Community Trial
Preventive Community Trial
The Preventive Community Trial is a controlled study that involves administration of preventive program or/and preventive treatments in community.
Preventive Community Trial
Research Activity
Preventive Community Trial
CL323594
C82455
Clinical Study Safety Issue and Lack of Effectiveness
owl:Class
Clinical Study Safety Issue and Lack of Effectiveness
Clinical Study Safety Issue and Lack of Effectiveness
Intellectual Product
CLINICAL STUDY SAFETY ISSUE AND LACK OF EFFECTIVENESS
Clinical Study Safety Issue and Lack of Effectiveness
Regulatory Assessment
Albumin Measurement
Protein or Enzyme Type Measurement
CDISC SDTM Laboratory Test Terminology by Code
Laboratory Procedure
CDISC
CDISC SDTM Terminology
ALB
Albumin
<def-source>CDISC</def-source><def-definition>A measurement of the albumin protein in a biological specimen.</def-definition>
Liver Function Test
owl:Class
C0201838
C64431
Albumin Measurement
Albumin Measurement
A quantitative measurement of albumin present in a sample.
CDISC SEND Terminology
Clinical Data Interchange Standards Consortium Terminology
Albumin Measurement
CDISC SDTM Laboratory Test Terminology by Name
Therapeutic Massage
Massage and Body Work
owl:Class
Massage and Body Work
Therapeutic or Preventive Procedure
CL002441
Manipulative and Body-Based Intervention Procedure
Massage and Body Work
Massage and Body Therapeutic Techniques
C15908
Massage and Body Work
Massage Therapy
CL370495
Rinse
Rinse
Rinse
Rinse
owl:Class
Clean
C65120
Activity
Any of several methods used to create alterations in a gene at a specific location.
Site-Directed Mutagenesis
Laboratory Procedure
Site-Directed Mutagenesis
Targeted Modification
owl:Class
C17378
Mutagenesis
C0079870
Site-Directed Mutagenesis
Targeted DNA Modification
Site-Directed Mutagenesis
Breast Cancer Diagnostic or Therapeutic Procedure
Breast Cancer Diagnostic or Therapeutic Procedure
Cancer Diagnostic or Therapeutic Procedure
Breast Cancer Diagnostic or Therapeutic Procedure
Breast Cancer Diagnostic or Therapeutic Procedure
owl:Class
C79427
Therapeutic or Preventive Procedure
owl:Class
Biopsy of Nose
Biopsy
Biopsy of Nose
Biopsy of Nose
CL354997
C51626
Removal of tissue from the nose for microscopic examination.
Diagnostic Procedure
Biopsy of Nose
Procedure_Has_Partially_Excised_Anatomy only Nose
CL017656
Genoplasty
Molecular Biology Research Technique
Genoplasty
Genoplasty
An alternative to traditional gene therapy, genoplasty is a repair technology that uses short DNA fragments to induce a cell to repair its genome.
Genoplasty
Gene Therapy
C16193
owl:Class
C51666
Partial Excision of Pancreas
Partial Pancreatectomy
owl:Class
Partial Pancreatectomy
Partial Pancreatectomy
CL354141
Procedure_Has_Partially_Excised_Anatomy only Pancreas
Surgical removal of part of the pancreas.
Pancreatectomy
Therapeutic or Preventive Procedure
Partial Pancreatectomy
LDH Isoenzyme 2/LDH
Laboratory Procedure
<def-definition>A relative measurement (ratio or percentage) of the lactate dehydrogenase isoenzyme 2 to total lactate dehydrogenase in a biological specimen.</def-definition><def-source>CDISC</def-source>
LDH Isoenzyme 2 to LDH Ratio Measurement
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Name
C79452
CDISC SEND Terminology
owl:Class
The determination of the ratio of LDH isoenzyme 2 compared to total LDH present in a sample. The measurement may be expressed as a ratio or percentage.
LDH Isoenzyme 2 to LDH Ratio Measurement
Protein or Enzyme Type Measurement
CDISC SDTM Terminology
LDH2LDH
CDISC SDTM Laboratory Test Terminology by Code
LDH Isoenzyme 2 to LDH Ratio Measurement
LDH Isoenzyme 2 to LDH Ratio Measurement
Diff-Quik Staining Method
Special Histology Staining Method
Diff-quik Staining Method
C23042
Diff-quik Staining Method
Diff-Quik Staining Method
Diff-Quik Staining Method
Laboratory Procedure
C0200973
Diff-quik Stain
owl:Class
Diff-Quik Staining Method
Diff-Quick is an alcoholic, quick staining method for cytology. It consists of two solutions: an eosinophilic (red) solution and a basophilic (blue) stain. It is used for identifying squamous epithelial cells, inflammatory cells, yeast, bacteria, etc.
Uric Acid Crystal Measurement
owl:Class
Uric Acid Crystal Measurement
CL384752
C74684
<def-source>CDISC</def-source><def-definition>A measurement of the uric acid crystals present in a biological specimen.</def-definition>
Uric Acid Crystal Measurement
Uric Acid Crystal Measurement
Laboratory Procedure
Crystal Growth Measurement
CDISC SEND Terminology
The determination of the amount of uric acid crystals present in a sample.
Uric Acid Crystals
CDISC SDTM Laboratory Test Terminology by Code
CDISC
CDISC SDTM Terminology
CYURIAC
CDISC SDTM Laboratory Test Terminology by Name
Clinical Data Interchange Standards Consortium Terminology
C71320
Videocapsule Endoscopy
CL371842
Videocapsule Endoscopy
owl:Class
Diagnostic Procedure
Videocapsule Endoscopy
Videocapsule Endoscopy
Diagnostic Endoscopic Procedure
Nuclear Transfer
Nuclear Transfer
Research Technique
Transfer of a nucleus from one cell to another.
C19562
owl:Class
Laboratory Procedure
CL004816
Nuclear Transfer
Nuclear Transfer
Saturated Non-esterified Fatty Acids Measurement
Laboratory Procedure
Saturated Non-esterified Fatty Acids Measurement
C80206
owl:Class
Saturated Non-esterified Fatty Acids Measurement
Fatty Acid Measurement
Saturated Non-esterified Fatty Acids Measurement
The determination of the amount of saturated non-esterified fatty acids present in a sample.
Prior Hormone Therapy
C15501
CL029664
Prior Antiestrogen Therapy
Prior Antiestrogen Therapy
Clinical Attribute
Prior Antiestrogen Therapy
Prior Antiestrogen Therapy
owl:Class
Laboratory Procedure
Eosinophil Count
Eosinophil Count
C64550
CDISC SDTM Laboratory Test Terminology by Name
Eosinophil Count
CDISC SEND Terminology
Clinical Data Interchange Standards Consortium Terminology
owl:Class
Eosinophil Count
<def-definition>A measurement of the eosinophils per unit of a biological specimen.</def-definition><def-source>CDISC</def-source>
Leukocyte Count
CDISC SDTM Terminology
C0200638
CDISC
Eosinophils
The determination of the number of eosinophils in a blood sample.
EOS
CDISC SDTM Laboratory Test Terminology by Code
DNA Analysis
owl:Class
Laboratory Procedure
Molecular Analysis
Any DNA based laboratory tests.
DNA Analysis
Diagnostic Procedure
DNA Analysis
C17632
C0200898
DNA Analysis
Hematopoietic Stem Cell Transplantation
Alternative Hematopoietic Cell Transplantation
CL375931
Alternative Hematopoietic Cell Transplantation
Therapeutic or Preventive Procedure
Alternative Hematopoietic Cell Transplantation
Alternative HCT
C70632
A procedure in which hematopoietic stem cells are given for another reason, not to reconstitute the patient's immune system.
owl:Class
Alternative Hematopoietic Cell Transplantation
C53463
Action
CL357384
The act of reaching a destination.
Arrival
Arrived
Arrival
Arrival
Activity
owl:Class
Arrival
Therapeutic or Preventive Procedure
pneumonectomy
Pneumonectomy
Pneumonectomy
The excision of part or all of a lung.
C0032284
<def-source>NCI-GLOSS</def-source><def-definition>(noo-mo-NEK-toe-mee) An operation to remove an entire lung.</def-definition>
Thoracic Surgical Procedure
Procedure_Has_Excised_Anatomy only Lung
Pneumonectomy
owl:Class
Pneumonectomy
C15305
Class Comparison
Class Comparison
CL364491
A type of analysis that determine the significance and/or magnitude of the difference between groups.
Class Comparison
owl:Class
Comparison
Activity
Class Comparison
C61038
C20080
angiography
Radiography
owl:Class
Angiography
CL378222
Diagnostic Procedure
Angiography
The X-ray examination of the blood vessels or chambers of the heart.
Angiography
<def-source>NCI-GLOSS</def-source><def-definition>(an-jee-AH-gra-fee) A procedure to x-ray blood vessels. The blood vessels can be seen because of an injection of a dye that shows up in the x-ray pictures.</def-definition>
Angiography
Cancer Antigen 19-9 Measurement
Cancer Antigen 19-9 Measurement
Cancer Antigen 19-9 Measurement
The determination of the amount of cancer antigen 19-9 present in a sample.
C81982
Cancer Antigen 19-9 Measurement
Immunology Test
owl:Class
C0038901
ophthalmological surgical procedure
Therapeutic or Preventive Procedure
owl:Class
Ophthalmologic Surgical Procedure
C15331
Ophthalmologic Surgical Procedure
Surgical Procedure by Site or System
eye surgery
Ophthalmologic Surgical Procedure
Surgery involving the eyes.
Procedure_Has_Target_Anatomy only Eye
Surgery, Ophthalmological
Ophthalmologic Surgical Procedure
Applied Research
Applied Research
C0681834
Applied Science
Applied Research
C15715
Research Activity
Applied Research
Research Activity
Research directed toward solving a specific problem.
owl:Class
Contrast with Basic Science
PHENTHZ
Phenothiazine Measurement
CDISC SDTM Laboratory Test Terminology by Code
Dibenzothiazine
C0202449
owl:Class
Phenothiazine Measurement
Phenothiazine Measurement
CDISC SEND Terminology
The determination of the amount of phenothiazine present in a sample.
Laboratory Procedure
Antipsychotic Measurement
<def-definition>A measurement of the phenothiazine present in a biological specimen.</def-definition><def-source>CDISC</def-source>
C74695
Phenothiazine Measurement
CDISC SDTM Terminology
Phenothiazine
Clinical Data Interchange Standards Consortium Terminology
CDISC SDTM Laboratory Test Terminology by Name
Smoking Cessation Intervention
Therapeutic or Preventive Procedure
CL000919
American Stop Smoking Intervention for Cancer Prevention
owl:Class
American Stop Smoking Intervention for Cancer Prevention
ASSIST
American Stop Smoking Intervention for Cancer Prevention
C19034
American Stop Smoking Intervention for Cancer Prevention
Smoking, Tobacco, and Cancer-ASSIST
A tobacco control trial conducted over the 7-year period from 1991-1998. It focused on helping smokers who want to quit, protecting nonsmokers from tobacco smoke, and discouraging the use of tobacco products among children.
Karyotyping
Cytogenetic Analysis
Karyotyping
Genetics, Karyotyping
<def-source>MSH2001</def-source><def-definition>Mapping of the full chromosome set of the nucleus of a cell. The chromosome characteristics of an individual or a cell line are usually presented as a systematized array of metaphase chromosomes from a photomicrograph of a single cell nucleus arranged in pairs in descending order of size and according to the position of the centromere. (From Stedman, 25th ed)</def-definition>
owl:Class
Karyotyping
C0022526
Karyotyping
The preparation, analysis, and interpretation of a karyotype, the representation of the chromosome set of a cell.
C16768
Laboratory Procedure
Swish
Swish
Swish
Instruction Imperative
Activity
owl:Class
C65124
Swish
CL370548
Peritoneal Dialysis
Peritoneal Dialysis
Dialysis
C0031139
Peritoneal Dialysis
Therapeutic or Preventive Procedure
C15297
<def-source>MSH2001</def-source><def-definition>Dialysis fluid being introduced into and removed from the peritoneal cavity as either a continuous or an intermittent procedure.</def-definition>
Peritoneal Dialysis
owl:Class
owl:Class
Interleukin 22 Measurement
CDISC SDTM Terminology
INTLK22
C74819
The determination of the amount of interleukin 22 present in a sample.
Interleukin 22 Measurement
Laboratory Procedure
<def-definition>A measurement of the interleukin 22 in a biological specimen.</def-definition><def-source>CDISC</def-source>
CDISC SEND Terminology
CL384300
Interleukin 22 Measurement
Cytokine Measurement
CDISC SDTM Laboratory Test Terminology by Name
Interleukin 22
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
Interleukin 22 Measurement
Culture Procedure
Culture
Culture Procedure
Microbiology Test
owl:Class
Culture Procedure
Culture Procedure
Any laboratory procedure for growing microorganisms.
C0430400
C25300
Laboratory Procedure
Cause Specific Survival
C53371
CL355696
owl:Class
Survival
Quantitative Concept
Cause Specific Survival
Cause Specific Survival
Cause Specific Survival
Study of Disease Mechanisms
owl:Class
Research Activity
Study of Disease Mechanisms
Study of Disease Mechanisms
Research Activity
The Study of Disease Mechanisms is either descriptive or analytic study that requires laboratory methods and clinical observations under controlled conditions to investigate disease etiology and/or pathogenesis, e.g. metabolic and pharmacologic studies.
CL323617
C39521
Study of Disease Mechanisms
Diagnostic Cystoscopy
Diagnostic Procedure
Diagnostic Endoscopic Procedure
Diagnostic Cystoscopy
Diagnostic Cystoscopy
owl:Class
Cystoscopy
Diagnostic Cystoscopy
C64945
C0401483
Exploratory Surgery
Exploratory Surgery
CL370729
owl:Class
<def-source>NCI-GLOSS</def-source><def-definition>(ek-SPLOR-uh-TOR-ee SER-juh-ree) Surgery to look inside the body to help make a diagnosis.</def-definition>
Diagnostic Procedure
Therapeutic or Preventive Procedure
Exploratory Surgery
C66747
Exploratory Surgery
Surgical Procedure
exploratory surgery
CDISC SDTM Laboratory Test Terminology by Name
Howell-Jolly Body Measurement
Howell-Jolly Bodies
Howell-Jolly Body Measurement
Laboratory Procedure
CDISC
CL384758
Howell-Jolly Body Measurement
CDISC SDTM Terminology
Howell-Jolly Body Measurement
The determination of the number of Howell-Jolly bodies present in a sample.
C74704
CDISC SDTM Laboratory Test Terminology by Code
Clinical Data Interchange Standards Consortium Terminology
owl:Class
CDISC SEND Terminology
<def-source>CDISC</def-source><def-definition>A measurement of the Howell-Jolly bodies (spherical, blue-black condensed DNA inclusions within the body of a red blood cell that appear under Wright-stain) in a biological specimen.</def-definition>
HOWJOL
Hematology Test
Tissue Plasminogen Activator Antigen Measurement
The determination of the amount of tissue plasminogen activator antigen present in a sample.
Immunology Test
owl:Class
Tissue Plasminogen Activator Antigen Measurement
Tissue Plasminogen Activator Antigen Measurement
Tissue Plasminogen Activator Antigen Measurement
C81993
The determination of the number of smudge cells present in a sample.
Smudge Cell Count
CDISC
C74627
Smudge Cell Count
Smudge Cell Count
Clinical Data Interchange Standards Consortium Terminology
Leukocyte Count
Smudge Cells
<def-source>CDISC</def-source><def-definition>A measurement of the smudge cells (the nuclear remnant of a ruptured white blood cell) in a biological specimen.</def-definition>
SMDGCE
CDISC SEND Terminology
owl:Class
Laboratory Procedure
Smudge Cell Count
CDISC SDTM Terminology
CL387840
Basket Cells
CDISC SDTM Laboratory Test Terminology by Code
CDISC SDTM Laboratory Test Terminology by Name
Aptamer Technology
Aptamer Technology
Aptamer Technology
Molecular Biology Research Technique
CL016926
owl:Class
Technologies that utilize aptamers for biosensors, diagnostic assays, therapeutics, etc.
Aptamer Technology
Molecular Genetic Technique
C20096
Biomarker Analysis
Health Care Activity
Intervention or Procedure
Biomarker Analysis
owl:Class
CL106534
Biomarker Analysis
C63333
Biomarker Analysis
Pre-Registration
Activity
C60537
Provisional Registration
owl:Class
Provisional Registration
The act of enrolling, contingent upon satisfactory results obtained from additional screening.
Registration
Provisional Registration
Provisional Registration
CL360177
Diagnostic Procedure
<def-source>NCI-GLOSS</def-source><def-definition>(BY-op-see) The removal of a sample of tissue from the bone marrow with a needle for examination under a microscope.</def-definition>
bone marrow biopsy
Bone Marrow Biopsy
Bone Marrow Biopsy
C15193
Biopsy of Bone Marrow
C0005954
Procedure_Has_Partially_Excised_Anatomy only 'Bone Marrow'
Bone Marrow Biopsy
Bone Marrow Biopsy
Biopsy
Biopsy, Bone Marrow
owl:Class
A biopsy involving the removal of a core tissue containing bone spicules and hematopoietic elements embedded in the marrow stroma. This procedure is done in the hip area mainly for the diagnosis and evaluation of neoplastic and non-neoplastic hematopoietic disorders (e.g. anemias, leukemias, lymphomas) and the evaluation of the spread of solid tumors (e.g. carcinomas, sarcomas) and lymphomas for therapeutic purposes.
owl:Class
Intellectual Product
LACK OF EXPECTED EFFECTIVENESS
Lack of Expected Effectiveness
C82456
Lack of Expected Effectiveness
Regulatory Assessment
Lack of Expected Effectiveness
Lack of Expected Effectiveness
Type Of Remedial Action ICSR Terminology
Inspection
Individual Case Safety Report Terminology
FDA
owl:Class
Inspection
Governmental or Regulatory Activity
Inspection
Inspection
C53604
CL357898
Remedial Action
Laboratory Procedure
owl:Class
CL365394
Microsatellite Instability Analysis
C63331
Microsatellite Instability Analysis
Molecular Analysis
Microsatellite Instability Analysis
Microsatellite Instability Analysis
Endarterectomy
Procedure_Has_Excised_Anatomy only 'Tunica Intima'
C52002
C0014098
Therapeutic or Preventive Procedure
Excision of an atheromatous plaque.
Endarterectomy
Endarterectomy
Cardiovascular Surgical Procedure
owl:Class
Endarterectomy
Gastrostomy
Gastrostomy
Digestive System Surgery
Ostomy
Creation of an opening between the stomach and the outside of the body.
C0017196
C52006
Gastrostomy
owl:Class
Procedure_Has_Target_Anatomy only Stomach
Gastrostomy
Therapeutic or Preventive Procedure
owl:Class
Research Activity
C0018757
Health Services Research
Outcomes and Health Services Research
Health Services Research
Health Services Research
The integration of epidemiologic, sociological, economic, and other analytic sciences in the study of health services. Health services research is usually concerned with relationships between need, demand, supply, use, and outcome of health services. The aim of the research is evaluation, particularly in terms of structure, process, output, and outcome. (From Last, Dictionary of Epidemiology, 2d ed)
C15245
Health Services Research
Therapeutic or Preventive Procedure
Infection Prophylaxis and Management
Antiviral Therapy
owl:Class
Infectious Diseases / Treatment, Viral
treatment of viral infectious disease
C0280274
Treatment of viral infections with agents that prevent viral replication in infected cells without impairing the host cell function.
Antiviral Therapy
Treatment of Infectious Diseases, Viral
Antiviral Therapy
Antiviral Therapy
C16119
Periodic Acid Schiff Staining Method
Periodic Acid Schiff Staining Method
C23019
Periodic Acid Schiff Staining Method
Periodic Acid Schiff
Laboratory Procedure
Periodic Acid Schiff Staining Method
Periodic Acid Schiff Staining Method
C0523213
PAS
Special Histology Staining Method
owl:Class
This is an all-round useful stain for many things, including glycogen, mucin, mucoprotein, glycoprotein, as well as fungi. The reaction is based on the oxidation of glycol group to aldehydes by periodate. The schiff's reagent selectively stains the aldehydes to a rose pink color. PAS is useful for outlining tissue structures--basement membranes, capsules, blood vessels, etc.
CL081088
Laboratory Procedure
Somatic Cell Hybridization
Somatic Cell Hybridization
Somatic Cell Hybridization
Research Activity
Fusion of 2 somatic cells to form a heterokaryon.
owl:Class
Somatic Cell Hybridization
Cell Fusion
C20622
Antibody-Drug Conjugate Therapy
C15508
CL375167
Treatment with injections of therapeutic substances linked with specific antibodies in order to directly destroy specific, usually cancerous, cells or to stimulate the immune system to destroy those cells.
Antibody-Drug Conjugate Therapy
Antibody-Drug Conjugate Therapy
Therapeutic or Preventive Procedure
Antibody-Drug Conjugate Therapy
Immunotherapy
owl:Class
Laboratory Procedure
C19651
owl:Class
CL008164
Shotgun Sequence Assembly
The assembly of a complete stretch of DNA sequence from a set of sub-sequences whose order in the longer stretch is unknown. Requires the use of computerized sequence analyses to determine the correct order of fragments in order to assemble to entire stretch of DNA sequence.
Shotgun Sequence Assembly
Shotgun Sequence Assembly
Molecular Analysis
Shotgun Sequence Assembly
A broad range of tests that are performed to assess how well lungs inhale and exhale air and how efficiently they transfer oxygen into the blood.
owl:Class
Pulmonary Function Test
Pulmonary Function Test
Diagnostic Procedure
C38081
Pulmonary Function Test
C0024119
Diagnostic Procedure
Pulmonary Function Test
Laboratory Procedure
Opioid Measurement
Opiod Metabolite Measurement
C74795
Opiod Metabolite Measurement
Opiod Metabolite Measurement
owl:Class
Opiod Metabolite Measurement
CL384335
The determination of the amount of any opioid metabolite present in a sample.
Renal Clearance
Renal Clearance
C0699829
The rate at which a substance is removed from the blood via the kidneys.
Renal Clearance
Renal Function Test
Laboratory Procedure
C75913
Renal Clearance
owl:Class
Drug Development
Drug Testing/Development, Clinical
Drug Development, Clinical
Research Activity
C15800
CL000332
Drug Development, Clinical
Drug Development, Clinical
owl:Class
Drug Development, Clinical
Training
owl:Class
Training
Educational Activity
To teach with hands-on experience
Educational Activity
Training
C17705
C0220931
Training
Training Programs
owl:Class
Therapeutic or Preventive Procedure
Helium-Ion Radiation
Radiation Ionizing Radiotherapy
Helium-Ion Radiation
Helium-Ion Radiation
C16098
CL008700
Helium-Ion Radiation
Linkage Analysis
Genetic Linkage Analysis
Genetic Linkage Analysis
Genetic Linkage Analysis
Molecular Analysis
Genetic Linkage
owl:Class
Laboratory Procedure
Genetic Linkage Analysis
The process of measuring the extent of crossovers between chromosomes as a gauge of the distance between genes.
C0796345
C16797
<def-source>MSH2001</def-source><def-definition>The association in inheritance of two or more non-allelic genes due to their being located more or less closely on the same chromosome.</def-definition>
Nutrition, Fats, Unsaturated
Role of unsaturated fats in cancer causation or prevention and in general health.
Nutrition, Fats, Unsaturated
C15233
owl:Class
Nutrition, Fats, Unsaturated
Lipid Nutrition, Unsaturated
Nutrition, Fats
C0015678
Nutrition, Fats, Unsaturated
Research Activity
Laboratory Procedure
Optical Trap
Nanotechnology Techniques
A method utilized for the non-mechanical manipulation of nanoparticles. Small transparent objects can be isolated or fixed using focused laser light. The optical trap is based on the concept of photon momentum transfer and has many applications.
Optical Trap
C62319
Optical Trap
C0872203
Optical Trap
owl:Class
C51794
Cardiac Diagnostic Procedure
Procedure_Has_Partially_Excised_Anatomy only Heart
Removal of tissue from the heart for microscopic examination.
owl:Class
Biopsy of Heart
Biopsy of Heart
Biopsy
Biopsy of Heart
Biopsy of Heart
Diagnostic Procedure
Cardiac Biopsy
CL354440
owl:Class
Production of genetic alterations by any technique, including chemicals, radiation, recombination, or other molecular biology methods.
Mutagenesis
Mutagenesis
Molecular Analysis
Mutagenesis
Molecular Biology, Mutagenesis
C17376
Laboratory Procedure
Mutagenesis
C0079866
Genetics-Mutagenesis
CL032196
Laboratory Procedure
Polymorphism Analysis
Polymorphism Detection
Polymorphism Analysis
Diagnostic Procedure
C18309
Mutation Detection
owl:Class
Polymorphism Analysis
Chemical or physical tests to determine DNA sequence variation
Polymorphism Analysis
DEFINITION
Display_Name
Concept_In_Subset
RdfType
ChildCount
FULL_SYN
FDA_Table
owl:disjointWith
code
ALT_DEFINITION
Contributing_Source
rdfs:subClassOf
DesignNote
Semantic_Type
Use_For
NSC_Number
BP_Synonym
UMLS_CUI
NCI_META_CUI
Concept_Status
Subsource
Preferred_Name
rdf:type
rdfs:label