Dennis G. Thomas
NanoParticle Ontology (NPO) represents the knowledge underlying the description, synthesis and characterization of nanoparticle formulations. The NPO provides the knowledge framework to support the annotation and semantic integration of data related to nanoparticles formulated in nanomedicine and nanotoxicology research. The NPO uses the Basic Formal Ontology (BFO) as its upper-level ontology and also uses terms from other biomedical ontologies to achieve interoperability with the other ontologies and to facilitate its expansion.
http://purl.bioontology.org/ontology/npo
The NPO was primarily developed by Dennis G. Thomas in collaboration with Nathan A. Baker and Rohit V. Pappu. This development was supported by the NIH through grants U54 CA119342 and U54 HG004028.
Currently, the NCI caBIG Nanotechnology Working Group (Nano WG) supports the use and development of the NPO.
NPO JIRA Tracker: https://tracker.nci.nih.gov/browse/NPO
2011-12-08 (yyyy-mm-dd)
Relation between a continuant and an occurrent in which the continuant participates in and causes the occurrence of that occurrent.
agent in
This relation is taken from the Ontology for Biomedical Investigations (OBI: Version 2009-11-06 Philly (aka version 1.0) Release Candidate)
A relation that indicates the process or property or substance analyzed in an assay.
analyze
A relation between an entity and a dependent continuant.
bearer of
A relation between a material continuant and an immaterial continuant, when the material continuant at any given time is located in but shares no parts in common with the immaterial continuant at the same time.
contained in
(source): OBO Relation Ontology (release version 0.99, date 07:14:2006); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005)
C contained_in C1; Cs are material continuants, C1s are immaterial continuants (holes, cavities): Every C at any given time is located in but shares no parts in common with C1 at the same time.
A reciprocal relation of contained_in, where given an immaterial continuant at some time, there is a material continuant contained in the immaterial continuant at the same time.
contains
(source): OBO Relation Ontology (release version 0.99, date 07:14:2006); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005)
C contains C1; Cs are immaterial continuants, C1s are material continuants: for all C, t, , if c is an instance of C at time t, then there is some c1 such that c1 is an instance of C1 and c1 contained_in c at t.
A relation which indicates the symbol that denotes something.
denoted by
A relation between distinct material continuants when one succeeds the other across a temporal divide in such a way that at least a significant portion of the matter of the earlier continuant is inherited by the later.
derives from
The temporal relation of derivation is more complex. Transformation, on the instance level, is just the relation of identity: each adult is identical to some child existing at some earlier time. Deri- vation on the instance-level is a relation holding between non-identicals. More precisely, it holds between distinct material continuants when one succeeds the other across a temporal divide in such a way that at least a biologically significant portion of the matter of the earlier continuant is inherited by the later. Thus we will have axioms to the effect that from c derives_from c1 we can infer that c and c1 are not identical and that there is some instant of time t such that c1 exists only prior to and c only subsequent to t. We will also be able to infer that the spatial region occupied by c as it begins to exist at t overlaps with the spatial region occupied by c1 as it ceases to exist in the same instant.
[source]:OBO Relation Ontology (release version 0.99, date 07:14:2006); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005)
A relation which indicates the property determined by a characterization.
determines property
document attribute
A relationship that indicates the bearer inhering a function.
function of
has Abstract
has Author
has DOI
has Journal Name
has PubMedID
has Publication Year
has Title
A relation which is between a process, a continuant and a time whenever the continuant is a participant in the process and is at the same time directly causally responsible for its occurrence.
has agent
(source): OBO Relation Ontology (release version 0.99, date 07:14:2006); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005)
Only material continuants can fill the agent role, that if c fills the agent role at t, then c must have existed at times earlier than t, that it must exercise its agent role for an interval of time including t, and so on.
P has_agent C; Ps are processes, Cs are material continuants.
Every P involves some C as agent (the C is involved in and is causally responsible for the P)
A relation which indicates the application or use of an entity.
has application
A relationship to indicate that one atom has a covalent bond with another atom.
has bond with
A relation used between material continuants where one is composed of the other. In the NPO, this relation is used mostly for representing the composition of nanoparticle formulations or nanoparticles.
has component part
is composed of
C has_component_part C1, means that every instance c of C is prepared from some instances c1 of C1 and a significant material portion of c1 becomes part of the constituting material of c when c begins to exist.
A has_component_part type of relation, which is used to infer that a particular component in a nanoparticle formulation is attached or chemically conjugated to some other chemical components of the same nanoparticle formulation by a method of attachment.
has conjugated component part
has attached component part
A relation which indicates the value of a property that can be quanitfied.
has datum value
A relationship to indicate that one atom has a double covalent bond with another atom.
has double bond with
A has_component_part type of relation, which is used to infer that a particular component (molecular structure or nanostructure) becomes encapsulated - due to non-covalent interactions - in a nanoparticle by a method of encapsulation.
has encapsulated component part
A relation that indicates the endpoint measured by an assay.
has endpoint of measurement
A has_component_part type of relation, which is used to infer that a particular component (molecular structure or nanostructure) is entrapped - due to non-covalent interactions - in a nanoparticle by a method of entrapment.
has entrapped component part
A relationship that indicates the function inhering in an entity.
has function
A relation which indicates the name of the type of identification, as well as other attributes of an entity.
has identification type
A relationship between a continuant and an occurrent that has other participating continuants, which holds iff at every time t an instance of the occurrent is created, there is at least one instance of the continuant participating in it at time t1 > t, and it is formed / derived from the instances of those continuants that participate at time t.
has output participant
Transitive parthood relation in which one entity has itself, or another entity as a part, and the relation is valid for use only between continuants or between occurrents but not between a continuant and an occurrent.
has part
(source): OBO Relation Ontology (release version 0.99, date 07:14:2006); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005)
If C and C1 are continuant classes, then C has_part C1 means that every instance of C at any time has part some instances of C1 at the same time.
[formal definition]: C has_part C1 holds true if and only if every continuant c that instantiates C at some time t, there is some continuant c1 that instantiates C1 at t such that c1 is part of c at t.
Examples:
fluorescein isothiocyanate has_part isothiocyanate group
gold quantum dot has_part gold
core-shell nanoparticle has_part core
core-shell nanoparticle has_part shell
If P and P1 are occurrent classes, then P has_part P1 means that every instance of P has part some instances of P1.
[formal definition]:P has_part P1 if and only if every occurrent p that instantiates P there is some occurrent p1 that instantiates P1 such that p1 is part of p.
Examples:
covalent linkage has_part covalent interaction
visualization of cellular uptake of nanoparticles has_part imaging of nanoparticles
A relationship between a continuant and an occurrent, which holds iff at every time an instance of the occurrent is created, it has atleast one instance of the continuant participating in it at the same time.
has participant
(source): OBO Relation Ontology (release version 0.99, date 07:14:2006); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005)
Examples:
nanoparticle-mediated drug delivery has_participant drug-loaded nanoparticle
If P is an occurrent class and C a continuant class, then P has_participant C means that every instance of P involves some instances of C as participants.
[formal definition]: P has_participant C hold true, if and only if every occurrent p that instantiates P there is some continuant c, and some time t, such that c instantiates C at t and p has participant c at t.
A relation between an entity and a specifically dependent continuant.
has property
A relation which indicates the quality inhering in an entity. It is a general relation between any class and subclasses of Quality.
has quality
A relationship to indicate that a class is related to another class.
has relation to
Relation between an independent continuant and a role.
has role
If C is an independent continuant and C1 a role continuant class, then C has_role R1 means that every instance of C fills some instances of role C1 everytime the role is realized in a particular context.
[source]: OBO Relation Ontology (release version 0.99, date 07:14:2006)
e.g., X (molecular entity) has_role Y (role), i.e, X fills the role of Y
A relationship to indicate tnat one atom has a single covalent bond with another atom.
has single bond with
A relation that indicates the temperature at which a process is performed.
has temperature condition
A relation that indicates the duration for a process to occur.
has time period
A relationship to indicate that one atom has a triple covalent bond with another atom.
has triple bond with
A relation which indicates the unit of a measured quantity.
has unit of measure
has unit
A relation that indicates the process or phenomenon signified by a measured endpoint of an assay.
indicator of
A relation between a dependent continuant D and an entity E. D inheres_in E iff: given any d that instantiates D at t, there exists some e that instantiates E at t and d *inheres_in* e at t. Here *inheres_in* is the primitive instance level relation. [source: OBI]
inheres in
A parthood relation that holds when C is part of C and C1 has part C, where C and C1 are continuant classes.
is integral part of
[source]: OBO Relation Ontology (release version 0.99); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005)
e.g.,carbon atom is_integral_part_of carbon (carbon is_a element)
A relationship between a realizable entity and an occurrent.
is realized in
executed during
has realization
is realized as
is realized by
This relation is taken from the Ontology for Biomedical Investigations (OBI: Version 2009-11-06 Philly (aka version 1.0) Release Candidate)
A relation which indicates a qualitative or quantitative measure (estimate) of an entity based on measurement, calculation, or counting.
measure of
A relation between two occurrents where one negatively regulates the other.
negatively regulates
blocks
inhibits
A relation which indicates the type of process that determines the value of a parameter.
parameter determined from
Transitive parthood relation in which one entity is part of another entity, and the relation is valid for use between continuants or between occurrents but not between a continuant and an occurrent.
part of
is part of
If C and C1 are continuant classes, then C part_of C1 means that every instance of C (c) at any time is part of some instances of C1 (c1) at the same time []. Note that whenever we read "some instances" it should be understood as reading "one or more instances".
[formal definition]: C part_of C1 holds true if and only if every continuant c that instantiates C at some time t, there is some continuant c1 that instantiates C1 at t such that c is part of c1 at t.
Examples:
carboxyl group part_of carboxylic acid
dendrimer generation layer part_of dendrimer
hydrophobic core of lipid bilayer part_of lipid bilayer
hollow core of nanocage part_of nanocage
If P and P1 are occurrent classes, then P part_of P1 means that every instance of P is part of some instances of P1.
[formal definition]: P part_of P1 holds true if and only if every occurrent p that instantiates P there is some process p1 that instantiates P1 such that p is part of p1.
Examples:
drug release from nanoparticle during systemic circulation part_of systemic circulation of drug-loaded nanoparticle
[source]: OBO Relation Ontology (release version 0.99, date 07:14:2006); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005)
A relationship between a continuant and an occurrent, which holds iff at every time an instance of the continuant is created, it participates in atleast one instance of the occurrent at the same time.
participates in
is_participant_of
Example:
catalyst participates_in catalytic reaction
fluorometer participates_in measurement of fluorescence intensity
If C is a continuant class and P an occurrent class, then C participates_in P means that every instance of C participates in some instances of P.
[formal definition]: C participates_in P if and only if every continuant c that instantiates C there is some occurrent p, and some time t, such that p instantiates P and c participates in p at t.
[source]: OBO Relation Ontology (release version 0.99, date 07:14:2006)
A relation between two occurrents where one positively regulates the other.
positively regulates
A relation which indicates the type of process that determines a qualitative or quantitative measure of the property.
property determined from
A relation which indicates the entity which bears a property.
property of
A relation between a quality and its bearer.
quality of
quality inheres in
A relation between an occurrent to a realizable entity.
realizes
is realization of
A relationship between two occurrents where one regulates the other.
regulates
A relationship indicating the bearer inhering a role.
role of
A relationship that indicates the response caused by a stimulus. (e.g., the response caused by the action of a stimulus on a nanoparticle)
stimulus causes response
A relationship which indicates the principle based on which a technique is used.
technique is based on
A relation which indicates the process for which the technique is used.
technique used for
A relation that indicates the quantity associated with a unit of measure. It is an inverse relation of "has unit of measure".
unit of
A relation which indicates that the type of instrument used in a process.
uses instrument
A relation which indicates the reagent used in an assay.
uses reagent
A relation which indicates the technique used for accomplishing a purpose.
uses technique
This relation is used to indicate other datum values that have to be specified/recorded when a particular datum value is recorded.
value specified at
Used to support NCI Edit tab
Concept_Status
Used to support Merge and Retire
OLD_CHILD
Used to support Merge and Retire
OLD_PARENT
Used to support Merge and Retire
OLD_ROLE
Used to support Split
Split_From
The number of protons in an atom.
atomic number
npo:GO_0007596
NPO_1988
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>For definition, please refer to Gene Ontology (v. 1.1.2341)</ncicp:def-definition><ncicp:attr>Gene Ontology (v. 1.1.2341)</ncicp:attr></ncicp:ComplexDefinition>
blood coagulation
blood coagulation
npo:NPO_100
NPO_100
NCIT:C63806
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shape formed by the surface of a 3-dimensional object, where points on the surface are at a fixed distance from a given straight line (axis of the cylinder).</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
cylindrical shape
cylindrical
cylindrical shape
npo:NPO_1002
NPO_1002
<ncicp:ComplexDefinition><ncicp:def-definition>A nucleic acid composed of nucleotides containing deoxyribose sugar and linked by phosphodiester bonds. DNA contains the genetic information of organisms.</ncicp:def-definition></ncicp:ComplexDefinition>
deoxyribonucleic acid
DNA
deoxyribonucleic acid
npo:NPO_101
NPO_101
<ncicp:ComplexDefinition><ncicp:def-definition>A non-metal which is any of the following elements: astatine, bromine, chlorine, fluorine, iodine.</ncicp:def-definition></ncicp:ComplexDefinition>
halogen
halogen
npo:NPO_1018
NPO_1018
<ncicp:ComplexDefinition><ncicp:def-definition>A nanomaterial which has one, two, or three external dimensions in the nanoscale size range.</ncicp:def-definition></ncicp:ComplexDefinition>
nano-object
nano-object
npo:NPO_1019
NPO_1019
<ncicp:ComplexDefinition><ncicp:def-definition>A quality inhering in a molecular entity because it consists of one or more atoms of the same element.</ncicp:def-definition></ncicp:ComplexDefinition>
homoatomic
homoatomic
npo:NPO_102
NPO_102
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spheroidal shape, which is generated by half-revolution of an ellipse around its major axis.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
prolate spheroidal shape
prolate spheroidal shape
npo:NPO_1020
NPO_1020
<ncicp:ComplexDefinition><ncicp:def-definition>A quality inhering in a molecular entity because it consists of more than one atom.</ncicp:def-definition></ncicp:ComplexDefinition>
polyatomic
polyatomic
npo:NPO_1021
NPO_1021
<ncicp:ComplexDefinition><ncicp:def-definition>A quality inhering in a molecular entity because it consists of only one atom.</ncicp:def-definition></ncicp:ComplexDefinition>
monoatomic
monoatomic
npo:NPO_1022
NPO_1022
<ncicp:ComplexDefinition><ncicp:def-definition>A quality inhering in a molecular entity because it consists of two or more chemical elements.</ncicp:def-definition></ncicp:ComplexDefinition>
heteroatomic
heteroatomic
13
npo:NPO_103
NPO_103
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 13.</ncicp:def-definition></ncicp:ComplexDefinition>
aluminium atom
aluminium atom
npo:NPO_104
NPO_104
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which is loaded with methotrexate.</ncicp:def-definition></ncicp:ComplexDefinition>
methotrexate-loaded nanoparticle
methotrexate-loaded nanoparticle
npo:NPO_105
NPO_105
<ncicp:ComplexDefinition><ncicp:def-definition>An element of Group 16 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
Group 16 Element
chalogen
Group 16 Element
npo:NPO_106
NPO_106
<ncicp:ComplexDefinition><ncicp:def-definition>The aqueous space enclosed by lipid bilayer of a liposome.</ncicp:def-definition></ncicp:ComplexDefinition>
hydrophilic core of liposome
hydrophilic core of liposome
npo:NPO_107
NPO_107
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 38.</ncicp:def-definition></ncicp:ComplexDefinition>
strontium
strontium
107
npo:NPO_108
NPO_108
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 107.</ncicp:def-definition></ncicp:ComplexDefinition>
bohrium atom
bohrium atom
npo:NPO_109
NPO_109
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which has a coating agent composed of a lipid.</ncicp:def-definition></ncicp:ComplexDefinition>
lipid-coated nanoparticle
lipid-coated nanoparticle
npo:NPO_110
NPO_110
<ncicp:ComplexDefinition><ncicp:def-definition>A carboxylate is an organic compound which is characterized by the presence of a carboxylate group. It has the structure R-C(=O)-[O-], where 'R' denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
carboxylate
carboxylate
npo:NPO_111
NPO_111
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 87.</ncicp:def-definition></ncicp:ComplexDefinition>
francium
francium
npo:NPO_1113
NPO_1113
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of carbon.</ncicp:def-definition></ncicp:ComplexDefinition>
carbon molecular entity
carbon molecular entity
npo:NPO_112
NPO_112
<ncicp:ComplexDefinition><ncicp:def-definition>A nanotube which consists of multiple layers or sheets of hexagonal arrays of an element or molecule, rolled in on themselves to form concentric seamless cylinders with a diameter close to 1 nanometer.</ncicp:def-definition></ncicp:ComplexDefinition>
multi-walled nanotube
multi-walled nanotube
npo:NPO_113
NPO_113
<ncicp:ComplexDefinition><ncicp:def-definition>An acyl halide group in which the halogen atom is a chlorine atom.</ncicp:def-definition></ncicp:ComplexDefinition>
acyl chloride group
acyl chloride group
npo:NPO_114
NPO_114
<ncicp:ComplexDefinition><ncicp:def-definition>A hydrophobic property by virtue of which the molecule is able to combine with or dissolve in lipids or fats.</ncicp:def-definition></ncicp:ComplexDefinition>
lipophilic
lipophilicity
lipophilic
npo:NPO_115
NPO_115
<ncicp:ComplexDefinition><ncicp:def-definition>An engineered nanomaterial which has an end-directed activity/function.</ncicp:def-definition></ncicp:ComplexDefinition>
nanodevice
nanodevice
npo:NPO_1155
NPO_1155
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative measure of polydispersity. It is a measure of the distribution of molecular mass in a given polymer sample or the distribution of particle sizes in a particulate sample. In polymeric samples, the polydispersity index is calculated as the weight average molecular weight divided by the number average molecular weight.</ncicp:def-definition><ncicp:Definition_Review_Date>100727</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
polydispersity index
PDI
polydispersity index
npo:NPO_1156
NPO_1156
<ncicp:ComplexDefinition><ncicp:def-definition>A dimensionless unit which denotes the ratio of weights.</ncicp:def-definition></ncicp:ComplexDefinition>
weight ratio
weight ratio
npo:NPO_1158
NPO_1158
<ncicp:ComplexDefinition><ncicp:def-definition>A quantitative measure of magnetism, which is a measure of the strength of a magnetic field over a given area.</ncicp:def-definition></ncicp:ComplexDefinition>
magnetic flux
magnetic flux
npo:NPO_1159
NPO_1159
<ncicp:ComplexDefinition><ncicp:def-definition>A unit of measurement for magnetic flux.</ncicp:def-definition></ncicp:ComplexDefinition>
magnetic flux unit
unit of magnetic flux
magnetic flux unit
npo:NPO_1163
NPO_1163
<ncicp:ComplexDefinition><ncicp:def-definition>The amount of magnetic flux in a unit area perpendicular to the direction of magnetic flow.</ncicp:def-definition></ncicp:ComplexDefinition>
magnetic flux density
magnetic flux density
npo:NPO_1164
NPO_1164
<ncicp:ComplexDefinition><ncicp:def-definition>A unit of measurement for magnetic flux density.</ncicp:def-definition></ncicp:ComplexDefinition>
magnetic flux density unit
unit of magnetic flux density
magnetic flux density unit
npo:NPO_1167
NPO_1167
PATO:0000033
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a substance by virtue of the amount of it there is mixed with another substance.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
concentration
concentration
npo:NPO_117
NPO_117
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which is derived by the removal of one chlorine atom from chlorosulfuric acid, and has the structure -S(=O)(=O)-Cl. The group is characteristic of sulfonyl chloride derivatives.</ncicp:def-definition></ncicp:ComplexDefinition>
sulfonyl chloride group
sulfonyl chloride group
npo:NPO_1171
NPO_1171
<ncicp:ComplexDefinition><ncicp:def-definition>The sum of the relative atomic masses of the constituent atoms of a molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
molecular weight
MW
molecular weight
npo:NPO_119
NPO_119
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A force of interaction between atoms, ions, molecules or groups.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
chemical interaction
chemical bonding
chemical interaction
npo:NPO_1190
NPO_1190
<ncicp:ComplexDefinition><ncicp:def-definition>The number of moles of a solute dissolved in a liter of solution.</ncicp:def-definition></ncicp:ComplexDefinition>
molarity
molar concentration
molarity
npo:NPO_1191
NPO_1191
<ncicp:ComplexDefinition><ncicp:def-definition>The number of moles of solute dissolved in one kilogram of solvent.</ncicp:def-definition></ncicp:ComplexDefinition>
molality
molal concentration
molality
npo:NPO_1192
NPO_1192
<ncicp:ComplexDefinition><ncicp:def-definition>Concentration of a solution expressed in gram equivalents of solute per liter.</ncicp:def-definition></ncicp:ComplexDefinition>
normality
normal concentration
normality
npo:NPO_1193
NPO_1193
<ncicp:ComplexDefinition><ncicp:def-definition>Concentration, which is the amount of cells in a medium.</ncicp:def-definition></ncicp:ComplexDefinition>
cell concentration
cell concentration
npo:NPO_1195
NPO_1195
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of toxicity which is the concentration of a drug or inhibitor that is required to inhibit a biological process or a participant's activity in that process by half. The realization of this realiable entity is the 50% inhibition of a biological process or the activity (molecular function) of a biological occurring chemical entity (e.g., gene, gene product)</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
IC50
half maximal inhibitory concentration
IC50
npo:NPO_1196
NPO_1196
NCIT:C16788
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of toxicity which is the concentration of a chemical or biologic preparation that is likely to cause death in 50% of animals or cells being tested. The realization of this realizable entity is the death of 50% of animals or cells.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
LC-50
LD-50
lethal concentration - 50%
lethal dose - 50%
LC-50
npo:NPO_1199
NPO_1199
<ncicp:ComplexDefinition><ncicp:def-definition>pH of value between 7 and 14.</ncicp:def-definition></ncicp:ComplexDefinition>
basic pH
alkaline pH
basic pH
npo:NPO_120
NPO_120
<ncicp:ComplexDefinition><ncicp:def-definition>An aminoacid which is polar in nature.</ncicp:def-definition></ncicp:ComplexDefinition>
polar aminoacid
polar aminoacid
npo:NPO_1200
NPO_1200
<ncicp:ComplexDefinition><ncicp:def-definition>pH of value between 0 and 7.</ncicp:def-definition></ncicp:ComplexDefinition>
acidic pH
acidic pH
npo:NPO_1201
NPO_1201
<ncicp:ComplexDefinition><ncicp:def-definition>pH of value equal to 7.</ncicp:def-definition></ncicp:ComplexDefinition>
neutral pH
neutral pH
npo:NPO_1202
NPO_1202
<ncicp:ComplexDefinition><ncicp:def-definition>A qualitative measure of acidity in the basic pH range.</ncicp:def-definition></ncicp:ComplexDefinition>
alkaline
basic
alkaline
npo:NPO_1203
NPO_1203
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A qualitative measure of acidity in the acidic pH range.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
acidic
acidic
npo:NPO_1204
NPO_1204
<ncicp:ComplexDefinition><ncicp:def-definition>The pH at which a particular molecule or surface carries no net electrical charge.</ncicp:def-definition></ncicp:ComplexDefinition>
isoelectric point
isoelectric point
npo:NPO_1206
NPO_1206
NCIT:C67242
<ncicp:ComplexDefinition><ncicp:def-definition>A unit of cell concentration which is equal to one cell in a volume of 1 microliter.</ncicp:def-definition></ncicp:ComplexDefinition>
cells per microliter
cells/µL
cells per microliter
npo:NPO_121
NPO_121
<ncicp:ComplexDefinition><ncicp:def-definition>An element of Group 2 (IUPAC style) of the periodic table: beryllium (Be), magnesium (Mg), calcium (Ca), strontium (Sr), barium (Ba) and radium (Ra).</ncicp:def-definition></ncicp:ComplexDefinition>
alkali earth metal
alkaline earth metal
alkali earth metal
npo:NPO_1217
NPO_1217
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality which denotes the amount of substance (matter).</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
amount of substance
amount of substance
npo:NPO_1219
NPO_1219
<ncicp:ComplexDefinition><ncicp:def-definition>Weight inhering in the body of an animal species.</ncicp:def-definition></ncicp:ComplexDefinition>
body weight
body weight
npo:NPO_122
NPO_122
NCIT: C62373
<ncicp:ComplexDefinition><ncicp:def-definition>A two-dimensional nanoparticle which is shaped like a long dowel and has diameter measured in the nanoscale.</ncicp:def-definition></ncicp:ComplexDefinition>
nanorod
[NCI_Thesaurus definition]: Nanoscale structures that are shaped like long dowels. The structures have a diameter that is measured in the nanoscale with an extended length parameter.
nanorod
npo:NPO_1220
NPO_1220
<ncicp:ComplexDefinition><ncicp:def-definition>Weight inhering in a tumor.</ncicp:def-definition></ncicp:ComplexDefinition>
tumor weight
tumor weight
npo:NPO_1235
NPO_1235
<ncicp:ComplexDefinition><ncicp:def-definition>Area of an object's surface.</ncicp:def-definition></ncicp:ComplexDefinition>
surface area
surface area
npo:NPO_124
NPO_124
NCIT:C2197
<ncicp:ComplexDefinition><ncicp:def-definition>An antimetastic agent, which prevents metastasis by interfering with the aggregation of tumor cells.</ncicp:def-definition></ncicp:ComplexDefinition>
anti-adhesion agent
anti-adhesion agent
npo:NPO_125
NPO_125
<ncicp:ComplexDefinition><ncicp:def-definition>An inner transition element which is any element in the series of 15 radioactive metallic elements with atomic numbers 89 (actinium) to 103 (lawrencium).</ncicp:def-definition></ncicp:ComplexDefinition>
Actinide
Actinide
npo:NPO_1252
NPO_1252
<ncicp:ComplexDefinition><ncicp:def-definition>An area unit which is equal to 10^[-18] m^[2].</ncicp:def-definition></ncicp:ComplexDefinition>
square nanometer
nm^[2]
square nanometer
npo:NPO_126
NPO_126
NCIT: C73455
<ncicp:ComplexDefinition><ncicp:def-definition>A two-dimensional nanoparticle which consists of one or more sheets of hexagonal arrays of an element or molecule, rolled into seamless cylinders with capped ends.</ncicp:def-definition></ncicp:ComplexDefinition>
nanotube
nanotube
npo:NPO_1267
NPO_1267
<ncicp:ComplexDefinition><ncicp:def-definition>A mass density unit which is equal to mass of an object in micrograms divided by the volume in milliliters.</ncicp:def-definition></ncicp:ComplexDefinition>
microgram per milliliter
µg/mL
micrograms per milliliter
microgram per milliliter
npo:NPO_1268
NPO_1268
<ncicp:ComplexDefinition><ncicp:def-definition>A mass density unit which is equal to mass of an object in micrograms divided by the volume in microliters.</ncicp:def-definition></ncicp:ComplexDefinition>
microgram per microliter
µg/µL
micrograms per microliter
microgram per microliter
npo:NPO_127
NPO_127
<ncicp:ComplexDefinition><ncicp:def-definition>Role of a surface modifying agent that is attached to the surface of a nanoparticle in a nanoparticle formulation.</ncicp:def-definition></ncicp:ComplexDefinition>
nanoparticle surface modifying role
nanoparticle surface modifying role
npo:NPO_128
NPO_128
<ncicp:ComplexDefinition><ncicp:def-definition>An iodoacetyl group is an organic group which has the structure -C(=O)-CH2-I. The group is characteristic of an iodoacetyl molecule in which it is attached either to a hydrogen atom or a carbon atom via single covalent bond.</ncicp:def-definition></ncicp:ComplexDefinition>
iodoacetyl group
iodoacetyl group
npo:NPO_1285
NPO_1285
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a continuant bearer by virtue of its relation to time during its existence.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
time quality
time quality
npo:NPO_1286
NPO_1286
PATO:0000011
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A time quality inhering in a bearer by virtue of how long it has existed.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
age
age
npo:NPO_129
NPO_129
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 17.</ncicp:def-definition></ncicp:ComplexDefinition>
chlorine
chlorine
npo:NPO_1292
NPO_1292
<ncicp:ComplexDefinition><ncicp:def-definition>A property of matter responsible for electrical phenomena.</ncicp:def-definition></ncicp:ComplexDefinition>
electric charge
charge
electric charge
npo:NPO_1293
NPO_1293
<ncicp:ComplexDefinition><ncicp:def-definition>A unit which is a measure of the quantity of charge.</ncicp:def-definition></ncicp:ComplexDefinition>
electric charge unit
charge unit
electric charge unit
npo:NPO_130
NPO_130
NCIT:C1821
<ncicp:ComplexDefinition><ncicp:def-definition>An anticancer drug that acts like estrogen on some tissues but blocks the effect of estrogen on other tissues.</ncicp:def-definition></ncicp:ComplexDefinition>
selective estrogen receptor modulator
selective estrogen receptor modulator
npo:NPO_1302
NPO_1302
NCIT:C62354
<ncicp:ComplexDefinition><ncicp:def-definition>The potential difference between the bulk dispersion medium (liquid) and the stationary layer of liquid near the surface of the dispersed particulate.</ncicp:def-definition></ncicp:ComplexDefinition>
zeta potential
zeta potential
npo:NPO_1303
NPO_1303
<ncicp:ComplexDefinition><ncicp:def-definition>An electric charge unit which which is approximately equal to 3.33564 × 10^[?10] C.</ncicp:def-definition></ncicp:ComplexDefinition>
statcoulomb
Fr
statC
Franklin
e.s.u.
electrostatic unit of charge
statcoulomb
npo:NPO_1304
NPO_1304
<ncicp:ComplexDefinition><ncicp:def-definition>A unit of electric charge where one ampere-hour is equal to 3600 coulombs.</ncicp:def-definition></ncicp:ComplexDefinition>
ampere hour
Ah
amp hour
ampere hour
npo:NPO_1305
NPO_1305
<ncicp:ComplexDefinition><ncicp:def-definition>An electric charge quality which signifies a deficiency of electrons in the bearer.</ncicp:def-definition></ncicp:ComplexDefinition>
positive charge
positively charged
positive charge
npo:NPO_1306
NPO_1306
<ncicp:ComplexDefinition><ncicp:def-definition>An electric charge quality which signifies a surplus of electrons in the bearer.</ncicp:def-definition></ncicp:ComplexDefinition>
negative charge
negatively charged
negative charge
npo:NPO_1307
NPO_1307
<ncicp:ComplexDefinition><ncicp:def-definition>An electric charge quality which signifies zero net charge in the bearer.</ncicp:def-definition></ncicp:ComplexDefinition>
neutral charge
neutrally charged
neutral charge
npo:NPO_1308
NPO_1308
PATO:0000161
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity which inheres in a continuant or a group of continuants under certain conditions, and it is realized through the occurrence of a process, activity or interaction per unit time.</ncicp:def-definition><ncicp:Definition_Review_Date>100429</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
rate
rate
npo:NPO_1309
NPO_1309
<ncicp:ComplexDefinition><ncicp:def-definition>The rate of suppression in tumor growth.</ncicp:def-definition></ncicp:ComplexDefinition>
tumor suppression rate
rate of tumor suppression
tumor suppression rate
npo:NPO_131
NPO_131
<ncicp:ComplexDefinition><ncicp:def-definition>An element in the first row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition>
Period 1 Element
Period 1 Element
npo:NPO_1310
NPO_1310
<ncicp:ComplexDefinition><ncicp:def-definition>The rate of change or movement in the mass (amount of matter) of a physical object.</ncicp:def-definition></ncicp:ComplexDefinition>
mass rate
mass rate
npo:NPO_1311
NPO_1311
<ncicp:ComplexDefinition><ncicp:def-definition>A measure of the change or movement of mass per unit time.</ncicp:def-definition></ncicp:ComplexDefinition>
mass rate unit
unit of mass rate
mass rate unit
npo:NPO_1312
NPO_1312
<ncicp:ComplexDefinition><ncicp:def-definition>A unit of mass rate expressed as kilograms per day.</ncicp:def-definition></ncicp:ComplexDefinition>
kilogram per day
kg/day
kilograms per day
kilogram per day
npo:NPO_1315
NPO_1315
<ncicp:ComplexDefinition><ncicp:def-definition>Mobility of a charged particle in electrophoresis, measured as the rate of migration (usually in cm/s) per unit electric field strength (usually V/cm) of the charged particle.</ncicp:def-definition></ncicp:ComplexDefinition>
electrophoretic mobility
electrophoretic mobility
npo:NPO_1317
NPO_1317
<ncicp:ComplexDefinition><ncicp:def-definition>A unit of measure of electrophoretic mobility.</ncicp:def-definition></ncicp:ComplexDefinition>
unit of electrophoretic mobility
unit of electrophoretic mobility
npo:NPO_1318
NPO_1318
<ncicp:ComplexDefinition><ncicp:def-definition>A unit of electrophoretic mobility of a charged particle moving with a velocity of 1cm/s in an electric field of strength equal to 1 volt/s.</ncicp:def-definition></ncicp:ComplexDefinition>
square centimeter per volt per second
cm^[2]/(V s)
square centimeter per volt per second
npo:NPO_132
NPO_132
<ncicp:ComplexDefinition><ncicp:def-definition>A sulfonyl chloride derivative is an organic compound which is characterized by the presence of a sulfonyl chloride group. It has the structure R-S(=O)(=O)-Cl, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
sulfonyl chloride derivative
sulfonyl chloride derivative
npo:NPO_1327
NPO_1327
<ncicp:ComplexDefinition><ncicp:def-definition>A percentage unit of molar concentration which is equal to 100 times the mole fraction (number of moles of solute in proportion to the total number of moles in a solution.</ncicp:def-definition></ncicp:ComplexDefinition>
mole percentage
% mol
mol %
percent of total moles
mole percentage
npo:NPO_133
NPO_133
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 106.</ncicp:def-definition></ncicp:ComplexDefinition>
seaborgium
seaborgium
npo:NPO_1333
NPO_1333
PATO:0001029
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity inhering in a bearer by virtue of ratio of the bearer's output to the bearer's input.</ncicp:def-definition><ncicp:Definition_Review_Date>100429</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
efficiency
efficiency
npo:NPO_1334
NPO_1334
<ncicp:ComplexDefinition><ncicp:def-definition>A quality inhering in a material entity by virtue of it having the capacity to carry an amount of another material entity.</ncicp:def-definition></ncicp:ComplexDefinition>
loading efficiency
loading efficiency
npo:NPO_1335
NPO_1335
<ncicp:ComplexDefinition><ncicp:def-definition>The efficiency inhering in a bearer's ability to facilitate transfection.</ncicp:def-definition></ncicp:ComplexDefinition>
transfection efficiency
transfection efficiency
npo:NPO_1336
NPO_1336
<ncicp:ComplexDefinition><ncicp:def-definition>The efficiency inhering in a nanomaterial or supramolecular structure by virtue of its capacity to encapsulate an amount of molecular entity, isotope or nanomaterial.</ncicp:def-definition></ncicp:ComplexDefinition>
encapsulation efficiency
encapsulation efficiency
npo:NPO_1337
NPO_1337
<ncicp:ComplexDefinition><ncicp:def-definition>A 3-D extent quality of the amount of 3-dimensional space a tumor occupies.</ncicp:def-definition></ncicp:ComplexDefinition>
tumor volume
tumor volume
npo:NPO_1338
NPO_1338
NCIT:C27990
<ncicp:ComplexDefinition><ncicp:def-definition>A realizable entity inhering in a bearer which causes harm to the growth and functioning of cells, tissues, organs and the body.</ncicp:def-definition></ncicp:ComplexDefinition>
toxicity
toxicity
npo:NPO_1339
NPO_1339
NCIT:C63814
<ncicp:ComplexDefinition><ncicp:def-definition>Toxicity that impairs or damages the immune system.</ncicp:def-definition></ncicp:ComplexDefinition>
immunotoxicity
immunotoxicity
npo:NPO_1340
NPO_1340
NCIT:C27988
<ncicp:ComplexDefinition><ncicp:def-definition>Toxicity that impairs or damages cells, and it is a desired property for the killing of growing tumor cells.</ncicp:def-definition></ncicp:ComplexDefinition>
cytotoxicity
cytotoxicity
npo:NPO_1341
NPO_1341
NCIT:C27955
<ncicp:ComplexDefinition><ncicp:def-definition>Toxicity that inheres in a drug which causes adverse effects, when the drug is used therapeutically or diagnostically.</ncicp:def-definition></ncicp:ComplexDefinition>
drug toxicity
drug toxicity
npo:NPO_1343
NPO_1343
<ncicp:ComplexDefinition><ncicp:def-definition>Viability of a cell to proliferate, grow, divide, or repair damaged cell components.</ncicp:def-definition></ncicp:ComplexDefinition>
cell viability
cell viability
npo:NPO_1344
NPO_1344
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in an object by virtue of the type, quantities or relative ratios of chemical components of the inhering entity.</ncicp:def-definition><ncicp:Definition_Review_Date>100701</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO:0000025 (composition)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
chemical composition
chemical composition
npo:NPO_1345
NPO_1345
<ncicp:ComplexDefinition><ncicp:def-definition>A composition quality which is the degree to which an object bearer is free of contaminants or heterogeneous components.</ncicp:def-definition></ncicp:ComplexDefinition>
purity
purity
npo:NPO_1351
NPO_1351
PATO:0001521
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>The maximum magnitude (value without regard to sign) of the disturbance of a sound wave.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
amplitude of sound wave
amplitude of sound
sound amplitude
amplitude of sound wave
npo:NPO_1355
NPO_1355
<ncicp:ComplexDefinition><ncicp:def-definition>An experiment performed to determine the distinctive characteristics (property / behavior) or essential features of a material entity.</ncicp:def-definition></ncicp:ComplexDefinition>
characterization
characterization
npo:NPO_1356
NPO_1356
<ncicp:ComplexDefinition><ncicp:def-definition>A type of characterization, which is performed to determine the physicochemical (material and structural) properties of an object.</ncicp:def-definition></ncicp:ComplexDefinition>
physicochemical characterization
physicochemical characterization
npo:NPO_1357
NPO_1357
<ncicp:ComplexDefinition><ncicp:def-definition>A type of characterization, which is performed to determine a property/quality that indicates the behavior of a material entity in vitro.</ncicp:def-definition></ncicp:ComplexDefinition>
in vitro characterization
in vitro characterization
npo:NPO_1358
NPO_1358
<ncicp:ComplexDefinition><ncicp:def-definition>A type of characterization, which is performed to determine a property/quality that indicates the behavior of a material entity in vivo.</ncicp:def-definition></ncicp:ComplexDefinition>
in vivo characterization
in vivo characterization
npo:NPO_1359
NPO_1359
<ncicp:ComplexDefinition><ncicp:def-definition>A type of physical characterization, which is performed to determine the molecular weight of a molecular entity.</ncicp:def-definition></ncicp:ComplexDefinition>
molecular weight characterization
molecular weight characterization
npo:NPO_136
NPO_136
MESH: D050256
NCIT: C273
<ncicp:ComplexDefinition><ncicp:def-definition>Antineoplastic agent that kills cancer cells by interfering with mitosis.</ncicp:def-definition></ncicp:ComplexDefinition>
antimitotic agent
antimitotic agent
npo:NPO_1360
NPO_1360
<ncicp:ComplexDefinition><ncicp:def-definition>A type of physical characterization, which is performed to determine the purity of a chemical substance.</ncicp:def-definition></ncicp:ComplexDefinition>
purity characterization
purity characterization
npo:NPO_1361
NPO_1361
<ncicp:ComplexDefinition><ncicp:def-definition>A type of physical characterization, which is performed to determine the shape of an object.</ncicp:def-definition></ncicp:ComplexDefinition>
shape characterization
shape characterization
npo:NPO_1362
NPO_1362
<ncicp:ComplexDefinition><ncicp:def-definition>A type of physical characterization, which is performed to determine the size of an object.</ncicp:def-definition></ncicp:ComplexDefinition>
size characterization
size characterization
npo:NPO_1363
NPO_1363
<ncicp:ComplexDefinition><ncicp:def-definition>A type of physical characterization, which is performed to determine the surface property of an object.</ncicp:def-definition></ncicp:ComplexDefinition>
surface characterization
surface characterization
npo:NPO_1364
NPO_1364
<ncicp:ComplexDefinition><ncicp:def-definition>A property inhering in the surface of an object.</ncicp:def-definition></ncicp:ComplexDefinition>
surface property
surface property
npo:NPO_1365
NPO_1365
<ncicp:ComplexDefinition><ncicp:def-definition>A dimensionless unit which denotes the ratio of longest and shortest dimensions of an object.</ncicp:def-definition></ncicp:ComplexDefinition>
aspect ratio
aspect ratio
npo:NPO_1366
NPO_1366
<ncicp:ComplexDefinition><ncicp:def-definition>A measure of diameter obtained by dividng a sum of several diameter values by the total number of values.</ncicp:def-definition></ncicp:ComplexDefinition>
average diameter
mean diameter
average diameter
npo:NPO_1367
NPO_1367
<ncicp:ComplexDefinition><ncicp:def-definition>A fiat material part which is a thin outer layer or film of material covering the surface of an object (e.g., a nanoparticle).</ncicp:def-definition></ncicp:ComplexDefinition>
coat
coating
surface coating
coat
npo:NPO_1370
NPO_1370
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which has magnetic property.</ncicp:def-definition></ncicp:ComplexDefinition>
magnetic nanoparticle
magnetic nanoparticle
npo:NPO_1373
NPO_1373
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which is bascially composed of silicon dioxide.</ncicp:def-definition></ncicp:ComplexDefinition>
silica nanoparticle
silicon dioxide nanoparticle
silica nanoparticle
npo:NPO_1374
NPO_1374
<ncicp:ComplexDefinition><ncicp:def-definition>An iron oxide nanoparticle which has superparamagnetic property.</ncicp:def-definition></ncicp:ComplexDefinition>
superparamagnetic iron oxide nanoparticle
SPIO nanoparticle
superparamagnetic iron oxide nanoparticle
npo:NPO_1375
NPO_1375
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which is basically composed of polymer.</ncicp:def-definition></ncicp:ComplexDefinition>
polymeric nanoparticle
polymer nanoparticle
polymeric nanoparticle
npo:NPO_1376
NPO_1376
PATO:0000018
<ncicp:ComplexDefinition><ncicp:def-definition>A disposition inhering in a bearer which emits light of longer wavelength during absorption of radiation of shorter (invisible) wavelength.</ncicp:def-definition></ncicp:ComplexDefinition>
fluorescent
fluorescence property
fluorescent
npo:NPO_1377
NPO_1377
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which has fluorescence property.</ncicp:def-definition></ncicp:ComplexDefinition>
fluorescent nanoparticle
fluorescent nanoparticle
npo:NPO_1378
NPO_1378
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which exists while dispersed in a hydrogel.</ncicp:def-definition></ncicp:ComplexDefinition>
hydrogel nanoparticle
hydrogel nanoparticle
npo:NPO_1379
NPO_1379
<ncicp:ComplexDefinition><ncicp:def-definition>The surface of a nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
surface of nanoparticle
nanoparticle surface
surface of nanoparticle
npo:NPO_138
NPO_138
<ncicp:ComplexDefinition><ncicp:def-definition>A linkage in which a molecular entity or nanostructure becomes enclosed due to non-covalent interactions, in a nanoparticle's material site that is fully bounded by the particle's constituting material.</ncicp:def-definition></ncicp:ComplexDefinition>
encapsulation
encapsulation
npo:NPO_1380
NPO_1380
NCIT:C799
<ncicp:ComplexDefinition><ncicp:def-definition>An isotope which releases radiation as it breaks down.</ncicp:def-definition></ncicp:ComplexDefinition>
radioisotope
radionuclide
radioisotope
npo:NPO_1382
NPO_1382
<ncicp:ComplexDefinition><ncicp:def-definition>Emission of particles or electromagnetic radiation caused by the spontaneous disintegration of atoms of unstable nuclei in order to form atoms with stable nuclei.</ncicp:def-definition></ncicp:ComplexDefinition>
radioactivity
radioactive decay
radioactivity
npo:NPO_1383
NPO_1383
PATO:0001741
<ncicp:ComplexDefinition><ncicp:def-definition>A disposition inhering in the bearer by virtue of it exhibiting or causing radioactivity.</ncicp:def-definition></ncicp:ComplexDefinition>
radioactive
radioactive
npo:NPO_1384
NPO_1384
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which is basically composed of a metal.</ncicp:def-definition></ncicp:ComplexDefinition>
metal nanoparticle
metallic nanoparticle
metal nanoparticle
npo:NPO_1388
NPO_1388
NCIT:C572
<ncicp:ComplexDefinition><ncicp:def-definition>An antibody which has molecular mass of 150-950 kDa, and consists of one or more basic units of four polypeptide chains comprising of two heavy chains and two light chains held together by disulphide links.</ncicp:def-definition></ncicp:ComplexDefinition>
immunoglobulin
Ig
immunoglobulin
npo:NPO_1389
NPO_1389
NCIT:C565
<ncicp:ComplexDefinition><ncicp:def-definition>An immunoglobulin isotype which is associated with antibody-mediated mucosal immunity. It is secreted as dimers into the mucosa and is the most effective isotype at fixing complement by the alternative pathway, even though it lacks the ability to fix complement by the classical pathway. There are two subtypes in the human - IgA1 and IgA2. [Source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
immunoglobulin A
IgA
immunoglobulin A
npo:NPO_1390
NPO_1390
NCIT:C566
<ncicp:ComplexDefinition><ncicp:def-definition>An immunoglobulin isotype, which is expressed on naive B cells along with IgM.[Source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
immunoglobulin D
IgD
immunoglobulin D
npo:NPO_1391
NPO_1391
NCIT:C567
<ncicp:ComplexDefinition><ncicp:def-definition>An immunoglobulin isotype, which has the unique ability to bind with high affinity to IgE receptors (FceRI) on mast cells and basophils and induce degranulation and cytokine production by these cells when they are crosslinked by antigen. In addition to a central role in atopy and allergic responses, it has been speculated that IgE-mediated mast cell degranulation, by its release of mediators that increase vascular permeability, has an important role in the initiation of immune response in general. [Source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
immunoglobulin E
IgE
immunoglobulin E
npo:NPO_1392
NPO_1392
NCIT:C568
<ncicp:ComplexDefinition><ncicp:def-definition>An immunoglobulin isotype, which characterizes secondary immune responses. This isotype is further broken down into several smaller subclasses (IgG1, IgG2a, IgG2b, IgG3 in the mouse; IgG1-4 in the human), and each subclass is differentially synthesized and secreted into the serum upon differential immune stimuli.[Source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
immunoglobulin G
IgG
immunoglobulin G
npo:NPO_1393
NPO_1393
NCIT:C569
<ncicp:ComplexDefinition><ncicp:def-definition>A main immunoglobulin isotype which is secreted during a primary immune response. IgM binds with low affinity but high avidity (multiple binding sites) because it not only occurs as monomers but also as pentamers and hexamers.[Source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
immunoglobulin M
IgM
immunoglobulin M
npo:NPO_1394
NPO_1394
<ncicp:ComplexDefinition><ncicp:def-definition>A class of immunoglobulins, which refers to genetic variations or differences in the constant region of the heavy chain of the Ig</ncicp:def-definition></ncicp:ComplexDefinition>
immunoglobulin isotype
immunoglobulin class
isotype
immunoglobulin isotype
npo:NPO_1395
NPO_1395
<ncicp:ComplexDefinition><ncicp:def-definition>A function which inheres in a material entity, and is realized in a process in which the material entity is used to target another material entity.</ncicp:def-definition></ncicp:ComplexDefinition>
targeting function
targeting function
npo:NPO_1396
NPO_1396
<ncicp:ComplexDefinition><ncicp:def-definition>A function inhering in a material entity by virtue of its use for imaging purposes.</ncicp:def-definition></ncicp:ComplexDefinition>
imaging function
imaging function
npo:NPO_1397
NPO_1397
<ncicp:ComplexDefinition><ncicp:def-definition>A function inhering in a material entity by virtue of its use for therapeutic purposes.</ncicp:def-definition></ncicp:ComplexDefinition>
therapeutic function
therapeutic function
npo:NPO_140
NPO_140
<ncicp:ComplexDefinition><ncicp:def-definition>An acyl halide compound is an acyl compound which is characterized by the presence of acyl halide group. It has the structure R-(C=O)-X, where 'R' denotes an organic group and X denotes a halogen atom (F, Cl, Br or I).</ncicp:def-definition></ncicp:ComplexDefinition>
acyl halide
acid halide
acyl halide
npo:NPO_1403
NPO_1403
<ncicp:ComplexDefinition><ncicp:def-definition>Chemiluminescence produced by living systems.</ncicp:def-definition></ncicp:ComplexDefinition>
bioluminescence
bioluminescence
npo:NPO_1404
NPO_1404
<ncicp:ComplexDefinition><ncicp:def-definition>A small representative portion of a nanoparticle formulation.</ncicp:def-definition></ncicp:ComplexDefinition>
nanoparticle sample
nanoparticle sample
npo:NPO_1405
[DGT, June 10, 2010]: Description for a specific type of technique could contain the following types of information: 1) principle used in the technique (e.g. NMR for NMR spectroscopy), 2) description of the principle if the term that describes the principle is not represented in the ontology, 3) tool used in a technique (e.g., scanning electron microscope in scanning electron miroscopy), 4) applications of the technique, and 5) information on how to use the technique for each type of application.
NPO_1405
<ncicp:ComplexDefinition><ncicp:def-definition>A systematic procedure or a practical method which is used for accomplishing a task.</ncicp:def-definition></ncicp:ComplexDefinition>
technique
technique
npo:NPO_1406
NPO_1406
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A process which is an established way of doing something.</ncicp:def-definition></ncicp:ComplexDefinition>
procedure
method
procedure
npo:NPO_1407
NPO_1407
<ncicp:ComplexDefinition><ncicp:def-definition>A scientific procedure which is a process of conducting a test under controlled conditions to make a discovery, test a hypothesis, or demonstrate a known fact.</ncicp:def-definition></ncicp:ComplexDefinition>
experiment
experiment
npo:NPO_1408
NPO_1408
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An experiment which is used to 1) analyze or measure (qualitatively/quantitatively) the composition and property of a substance; or, 2) to analyze a process or activity.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
assay
assay
npo:NPO_1409
NPO_1409
NCIT:C15958
<ncicp:ComplexDefinition><ncicp:def-definition>A bioassay conducted in an artificial environment (e.g., test tube) outside the body of a living organism, under controlled conditions.</ncicp:def-definition></ncicp:ComplexDefinition>
in vitro assay
in vitro bioassay
in vitro assay
npo:NPO_141
NPO_141
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which has the structure -S-. The group is characteristic of thioether wherein the sulfur atom is attached to two carbon atoms via single covalent bonds.</ncicp:def-definition></ncicp:ComplexDefinition>
thioether group
thioether group
npo:NPO_1410
NPO_1410
<ncicp:ComplexDefinition><ncicp:def-definition>A bioassay conducted inside the body of a living organism.</ncicp:def-definition></ncicp:ComplexDefinition>
in vivo assay
in vivo bioassay
in vivo assay
npo:NPO_1411
NPO_1411
<ncicp:ComplexDefinition><ncicp:def-definition>An assay which is used to test or analyse the biological activity of a substance, and which is performed by studying its effect on an organism or in a test tube under controlled conditions.</ncicp:def-definition></ncicp:ComplexDefinition>
bioassay
bioassay
npo:NPO_1412
NPO_1412
<ncicp:ComplexDefinition><ncicp:def-definition>An assay for evaluating the physical properties of a sample.</ncicp:def-definition></ncicp:ComplexDefinition>
physical assay
physical assay
npo:NPO_1413
NPO_1413
<ncicp:ComplexDefinition><ncicp:def-definition>Characterization of nanoparticles or nanoparticle formulations.</ncicp:def-definition></ncicp:ComplexDefinition>
nanoparticle characterization
characterization of nanoparticle
nanoparticle characterization
npo:NPO_1414
NPO_1414
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A compound or molecule used for stabilizing an emulsion.</ncicp:def-definition></ncicp:ComplexDefinition>
emulsifier
emulsifying agent
emulsifier
npo:NPO_1415
NPO_1415
<ncicp:ComplexDefinition><ncicp:def-definition>A technique which uses a microscope to study a material object or a process that cannot be seen by the naked eye.</ncicp:def-definition></ncicp:ComplexDefinition>
microscopy
microscopy technique
microscopy
npo:NPO_1416
NPO_1416
<ncicp:ComplexDefinition><ncicp:def-definition>A technique which is used to separate substances from mixtures.</ncicp:def-definition></ncicp:ComplexDefinition>
separation technique
separation method
separation technique
npo:NPO_1417
NPO_1417
<ncicp:ComplexDefinition><ncicp:def-definition>A separation technique which uses a centrifuge to generate a centrifugal force for separating fluids of different densities from mixtures or for separating liquids from solids.</ncicp:def-definition></ncicp:ComplexDefinition>
centrifugation
centrifugation
npo:NPO_1418
NPO_1418
<ncicp:ComplexDefinition><ncicp:def-definition>A separation technique used for separating charged particles in a fluid or gel under the action of an electric field. The electric field causes the movement of charged particles.</ncicp:def-definition></ncicp:ComplexDefinition>
electrophoresis
electrophoresis
npo:NPO_1419
NPO_1419
NCIT:C18091
<ncicp:ComplexDefinition><ncicp:def-definition>Electrophoresis method used for separating molecules of proteins and nucleic acids from a sample mixture of similar molecules through a gelatinous matrix. Subject to an electric field, each molecule in the sample mixture migrates through the matrix at a different rate, depending mainly on electrical charge and size, resulting in spatial separation within the matrix of each molecular species in the sample mixture. Agarose and acrylamide in a cylindrical tube or slab gel are commonly used media for electrophoresis of proteins and nucleic acids.</ncicp:def-definition></ncicp:ComplexDefinition>
gel electrophoresis
gel electrophoresis
npo:NPO_1420
NPO_1420
NCIT:C16537
<ncicp:ComplexDefinition><ncicp:def-definition>Gel electrophoresis in which highly purified agar is used as the diffusion medium.</ncicp:def-definition></ncicp:ComplexDefinition>
agarose gel electrophoresis
agarose gel electrophoresis
npo:NPO_1421
NPO_1421
NCIT:C16539
<ncicp:ComplexDefinition><ncicp:def-definition>Gel electrophoresis technique in which a polyacrylamide gel is used as the diffusion medium.</ncicp:def-definition></ncicp:ComplexDefinition>
polyacrylamide gel electrophoresis
polyacrylamide gel electrophoresis
npo:NPO_1422
NPO_1422
<ncicp:ComplexDefinition><ncicp:def-definition>A process of examining the component parts of a whole and their relations in making up the whole [source: WordNet]. e.g., the identification and measurement of chemical constituents of a substance or specimen.</ncicp:def-definition></ncicp:ComplexDefinition>
analysis
analysis
npo:NPO_1423
NPO_1423
<ncicp:ComplexDefinition><ncicp:def-definition>Analysis of protein components in a sample.</ncicp:def-definition></ncicp:ComplexDefinition>
protein analysis
analysis of proteins
protein analysis
npo:NPO_1424
NPO_1424
NCIT:C16357
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A technique which is used for the detection or identification of proteins or peptides that have been separated by gel electrophoresis and transferred onto nitrocellulose or other type of paper or nylon membrane. The proteins are then detected by reaction with enzymatically labeled or radiolabeled antibody probes.</ncicp:def-definition><ncicp:Definition_Review_Date>100614</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
western blot analysis
western blot
western blotting
western blotting technique
western blot analysis
npo:NPO_1425
NPO_1425
<ncicp:ComplexDefinition><ncicp:def-definition>A process or action of identifying the presence of something.</ncicp:def-definition></ncicp:ComplexDefinition>
detection
detection
npo:NPO_1426
NPO_1426
<ncicp:ComplexDefinition><ncicp:def-definition>Detection of proteins or a protein components in a sample.</ncicp:def-definition></ncicp:ComplexDefinition>
detection of proteins
protein detection
detection of proteins
npo:NPO_1427
NPO_1427
<ncicp:ComplexDefinition><ncicp:def-definition>A polyacrylamide gel electrophoresis technique for separating proteins in a sample which is prepared with sodium dodecyl sulfate (SDS) as a buffer that maintains the proteins in their denatured states.</ncicp:def-definition></ncicp:ComplexDefinition>
SDS polyacrylamide gel electrophoresis
SDS-PAGE
sodium dodecyl sulfate - polyacrylamide gel electrophoresis
SDS polyacrylamide gel electrophoresis
npo:NPO_1428
NPO_1428
<ncicp:ComplexDefinition><ncicp:def-definition>A microscopy technique based on the use of electron microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
electron microscopy
electron microscopy
npo:NPO_1429
NPO_1429
<ncicp:ComplexDefinition><ncicp:def-definition>An electron microscopy technique based on the use of scanning electron microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
scanning electron microscopy
SEM technique
scanning electron microscopy
npo:NPO_1430
NPO_1430
<ncicp:ComplexDefinition><ncicp:def-definition>An electron microscopy technique based on the use of transmission electron microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
transmission electron microscopy
TEM technique
A light source at the top of the TEM emits the electrons that travel through vacuum in the column of the microscope. Instead of glass lenses focusing the light in the light microscope, the TEM uses electromagnetic lenses to focus the electrons into a very thin beam. The electron beam then travels through the specimen you want to study. Depending on the density of the material present, some of the electrons are scattered and disappear from the beam. At the bottom of the microscope the unscattered electrons hit a fluorescent screen, which gives rise to a shadow image of the specimen with its different parts displayed in varied darkness according to their density. The image can be studied directly by the operator or photographed with a camera. [source: http://Nobelprize.org]
transmission electron microscopy
npo:NPO_1431
NPO_1431
<ncicp:ComplexDefinition><ncicp:def-definition>A microscopy technique based on the use of optical microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
optical microscopy
light microscopy
optical microscopy
npo:NPO_1432
NPO_1432
<ncicp:ComplexDefinition><ncicp:def-definition>An optical microscopy technique based on the use of fluorescence microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
fluorescence microscopy
fluorescence microscopy
npo:NPO_1433
NPO_1433
NCIT:C20346
<ncicp:ComplexDefinition><ncicp:def-definition>A microscopy technique based on the use of scanning probe microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
scanning probe microscopy
scanning probe microscopy
npo:NPO_1434
NPO_1434
<ncicp:ComplexDefinition><ncicp:def-definition>A scanning probe microscopy technique based on the use of atomic force microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
atomic force microscopy
scanning force microscopy
atomic force microscopy
npo:NPO_1435
NPO_1435
<ncicp:ComplexDefinition><ncicp:def-definition>A scanning probe microscopy technique based on the use of scanning tunneling microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
scanning tunneling microscopy
scanning tunneling microscopy
npo:NPO_1436
NPO_1436
<ncicp:ComplexDefinition><ncicp:def-definition>A device or tool that requires skill for proper use, and it is intended for a purpose.</ncicp:def-definition></ncicp:ComplexDefinition>
instrument
equipment
instrument
npo:NPO_1437
NPO_1437
NCIT:C20677
<ncicp:ComplexDefinition><ncicp:def-definition>An instrument which is used for magnifying and viewing images of objects that are too small to be seen by the naked or unaided eye. [source:http://encyclopedia.thefreedictionary.com/microscope]</ncicp:def-definition></ncicp:ComplexDefinition>
microscope
microscope
npo:NPO_1438
NPO_1438
NCIT:C28219
<ncicp:ComplexDefinition><ncicp:def-definition>A microscope that is similar in purpose to a light microscope but achieves much greater resolving power by using a parallel beam of electrons to illuminate the object instead of a beam of light. [source:WordNet 3.0]</ncicp:def-definition></ncicp:ComplexDefinition>
electron microscope
Electron Microscopes(EMs) function exactly as their optical counterparts except that they use a focused beam of electrons instead of light to "image" the specimen and gain information as to its structure and composition. The basic steps involved in all EMs: 1. A stream of electrons is formed (by the Electron Source) and accelerated toward the specimen using a positive electrical potential 2. This stream is confined and focused using metal apertures and magnetic lenses into a thin, focused, monochromatic beam. 3. This beam is focused onto the sample using a magnetic lens 4. Interactions occur inside the irradiated sample, affecting the electron beam These interactions and effects are detected and transformed into an image The above steps are carried out in all EMs regardless of type. [source: http://unl.edu/CMRAcfem/em.htm]
electron microscope
npo:NPO_1439
NPO_1439
NCIT:C28265
<ncicp:ComplexDefinition><ncicp:def-definition>A microscope which uses visible light and a system of lenses to magnify images of small objects.[source: http://encyclopedia.thefreedictionary.com]</ncicp:def-definition></ncicp:ComplexDefinition>
optical microscope
light microscope
optical microscope
53
npo:NPO_144
NPO_144
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 53.</ncicp:def-definition></ncicp:ComplexDefinition>
iodine atom
iodine atom
npo:NPO_1440
NPO_1440
NCIT:C78814
<ncicp:ComplexDefinition><ncicp:def-definition>An electron microscope which scans the surface of a sample with a beam of electrons and detects the interaction of the electrons with the atoms on the surface to produce a topographical image of the sample.</ncicp:def-definition></ncicp:ComplexDefinition>
scanning electron microscope
SEM
scanning electron microscope
npo:NPO_1441
NPO_1441
NCIT: C78813
<ncicp:ComplexDefinition><ncicp:def-definition>An electron microscope which transmits a beam of electrons through a finely sliced section of a specimen/sample and creates an image of the specimen/sample based on its effect on the phase of the electrons that pass through.</ncicp:def-definition></ncicp:ComplexDefinition>
transmission electron microscope
TEM
TEMs use electrons as light source and their much lower wavelength makes it possible to get a resolution a thousand times better than with a light microscope.[source: http://Nobelprize.org]
transmission electron microscope
npo:NPO_1442
NPO_1442
NCIT:C78803
<ncicp:ComplexDefinition><ncicp:def-definition>A microscope which forms images of surfaces using a physical probe that scans the specimen and records the probe-surface interaction as a function of position.</ncicp:def-definition></ncicp:ComplexDefinition>
scanning probe microsope
SPM
scanning probe microsope
npo:NPO_1443
NPO_1443
<ncicp:ComplexDefinition><ncicp:def-definition>An optical microscope which is used to study the properties of a specimen or sample based on the phenomena of fluorescence and phosphorescence. The microscope has a filter which allows radiation of a specific wavelength of light to pass through.The specimen or the sample contains components labeled with a fluorescent molecule which absorbs this light, and then emits light of a longer wavelength. A second filter of the microscope separates the emitted light from the brighter excitation light (shorter wavelength). As a result, the fluorescing regions of the sample shine out against a dark background with high contrast, when observed through the microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
fluorescence microscope
[definition: adapted from http://nobelprize.org; http://en.wikipedia.org/wiki/Fluorescence_microscope ]
fluorescence microscope
npo:NPO_1445
NPO_1445
NCIT:C78804
<ncicp:ComplexDefinition><ncicp:def-definition>A scanning probe microscope which consists of a microscale cantilever with a sharp tip (probe) at its end that is used to scan the specimen surface. The probe is extremely close to - but does not touch-the surface. As the probe traverses the surface, attractive and repulsive forces arising between it and the atoms on the surface induce forces on the probe that bend the cantilever. The amount of bending is measured and recorded, providing a map of the atoms on the surface. Atomic force microscopes can achieve magnification of a factor of 5 × 10^6, with a resolution of 2 angstroms, sufficient to resolve individual carbon atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
atomic force microscope
AFM
SFM
scanning force microscope
[definition: adapted from NCIT, http://www.thefreedictionary.com, http://en.wikipedia.org]
atomic force microscope
npo:NPO_1446
NPO_1446
NCIT:C17374
<ncicp:ComplexDefinition><ncicp:def-definition>A scanning probe microscope which consists of a probe with a small voltage applied to it ending in a tiny sharp electrically conducting tip (ideally consisting of one atom) that is moved close the material's surface. It scans the surface of a sample with a beam of electrons, causing a narrow channel of tunneling electrons to flow between the sample and the beam, and producing three-dimensional images of atomic topography and structure.</ncicp:def-definition></ncicp:ComplexDefinition>
scanning tunneling microscope
STM
[definition: adapted from http://www.thefreedictionary.com]
scanning tunneling microscope
npo:NPO_1447
NPO_1447
<ncicp:ComplexDefinition><ncicp:def-definition>A scanning probe microscope which is derived from atomic force microscope, having a magnetized tip that map the spatial distribution of magnetism by measuring the magnetic interactions between the sample and the tip. It is used to study magnetic materials.</ncicp:def-definition></ncicp:ComplexDefinition>
magnetic force microscope
MFM
[definition: adapted from http://encyclopedia.thefreedictionary.com]
magnetic force microscope
npo:NPO_145
NPO_145
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which is loaded with doxorubicin.</ncicp:def-definition></ncicp:ComplexDefinition>
doxorubicin-loaded nanoparticle
adriamycin-loaded nanoparticle
doxorubicin-loaded nanoparticle
npo:NPO_1451
NPO_1451
<ncicp:ComplexDefinition><ncicp:def-definition>A transmission electron microscopy technique based on the use of high resolution transmission electron microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
high resolution transmission electron microscopy
high resolution transmission electron microscopy
npo:NPO_1452
NPO_1452
<ncicp:ComplexDefinition><ncicp:def-definition>A transmission electron microscope which operates at an imaging mode that allows the imaging of the crystallographic structure of a sample at an atomic scale. In this mode, the transmitted and the diffracted beams of electrons are allowed to interfere to produce phase-contrast images.</ncicp:def-definition></ncicp:ComplexDefinition>
high resolution transmission electron microscope
HRTEM
[definition source]: http://en.wikipedia.org
high resolution transmission electron microscope
npo:NPO_1453
NPO_1453
<ncicp:ComplexDefinition><ncicp:def-definition>A transmission electron microscope with which a beam of electrons pass through the specimen, where the beam is focused into a narrow spot that is scanned over the sample specimen in a raster.</ncicp:def-definition></ncicp:ComplexDefinition>
scanning transmission electron microscope
STEM
scanning transmission electron microscope
npo:NPO_1454
NPO_1454
<ncicp:ComplexDefinition><ncicp:def-definition>A transmission electron microscopy technique based on the use of scanning transmission electron microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
scanning transmission electron microscopy
scanning transmission electron microscopy
npo:NPO_1455
NPO_1455
<ncicp:ComplexDefinition><ncicp:def-definition>An optical microscope which generates contrast within the specimen by exploiting phase differences between a specimen (sample) light ray and a reference ray. The sample and reference rays are created after the ray traverses, and is phase-distorted by, the sample. The phased ray then is split into two equally phased, but spatially separated ("sheared") rays by the action of a Wollaston prism. Finally, the ray-pairs pass through a polarizing filter where they are vibrationally recombined and interact at the image plane. It is the wave interference of these two rays that creates contrast.</ncicp:def-definition></ncicp:ComplexDefinition>
differential interference contrast microscope
DIC microscope
DIC microscope is based on interferometry, which is the technique of superposing (interfering) two or more waves, to detect differences between them. In interferometry, a single ray of light is split into two rays, one traversing and the other missing the specimen but interacting with the background. The rays are then recombined at the image plane, where wave interference may occur. Image contrast can be modified by altering the phase difference between the reference and specimen rays. [source: http://encyclopedia.thefreedictionary.com]
differential interference contrast microscope
npo:NPO_1456
NPO_1456
<ncicp:ComplexDefinition><ncicp:def-definition>An optical microscopy based on the use of differential interference contrast microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
differential interference contrast microscopy
differential interference contrast microscopy
npo:NPO_146
NPO_146
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle response to stimulus, which occurs in response to the external stimulus acting on the nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
nanoparticle response to external stimulus
nanoparticle response to external stimulus
npo:NPO_1465
NPO_1465
NCIT:C16585
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A technique for counting, examining and sorting microscopic particles (e.g., single cells) suspended in a stream of fluid that passes through a beam of light. It allows for multiple analyses of the physical and chemical characteristics of single cells flowing through an optical and/or electrical detection apparatus.</ncicp:def-definition><ncicp:Definition_Review_Date>100617</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
flow cytometry
[definition: adapted from NCIT, http://encyclopedia.thefreedictionary.com]
flow cytometry
npo:NPO_1467
NPO_1467
<ncicp:ComplexDefinition><ncicp:def-definition>A light scattering technique for measuring the electrophoretic mobilities of charged particles suspended in nonpolar media (i.e. solvents with much lower relative permittivities than water).</ncicp:def-definition></ncicp:ComplexDefinition>
phase analysis light scattering
PALS
[definition: adapted from http://www.unisa.edu.au/laser/Research/PALS.asp]
phase analysis light scattering
npo:NPO_1468
NPO_1468
NCIT: C17155
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A technique which is used for measuring the intensity of electromagnetic radiation that is absorbed, emitted (radiated), or scattered at different wavelengths or frequencies by a molecular entity or substance. This technique is used in studying the interaction of electromagnetic radiation with matter.</ncicp:def-definition><ncicp:Definition_Review_Date>100611</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
spectroscopy
spectroscopic technique
spectroscopy
npo:NPO_1469
NPO_1469
NCIT:C62329
<ncicp:ComplexDefinition><ncicp:def-definition>A spectroscopic technique which utilizes a laser beam to irradiate a sample containing particles in suspension, resulting in light scattering.When the scattered light is collected over a small solid angle, the light will exhibit intensity fluctuations. This is because the Brownian motion of the scatterers causes the phase of the light scattered from each particle to change with time, hence the total scattered intensity also fluctuates with time. The rapid fluctuations in scattering intensity, collected around a mean value at a certain angle, will depend on the particle diffusion and on the particle size. For a given temperature and viscosity, a calculated correlation function yields a diffusion coefficient, which can be used to calculate particle size.</ncicp:def-definition></ncicp:ComplexDefinition>
dynamic light scattering
DLS
PCS
QELS
Quasi-Elastic Light Scattering
photon correlation spectroscopy
[definition source: NCI]
dynamic light scattering
npo:NPO_147
NPO_147
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A pure substance which is made up of more than one type of atom, and can be decomposed into its elements by chemical methods. This class includes terms that can be used to describe molecules or compounds. A molecule is a group of atoms bonded together, representing the smallest fundamental unit of a chemical compound that can take part in a chemical reaction.</ncicp:def-definition></ncicp:ComplexDefinition>
compound or molecule
compound or molecule
npo:NPO_1470
NPO_1470
NCIT:C16810
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An absorption spectroscopic technique which uses NMR (nuclear magnetic resonance) to basically measure the frequency (resonant frequency) of vibrating nuclei (having non-zero spin) of a given type in the presence of a magnetic field. When placed in a magnetic field, nuclei that have non-zero spins absorb frequency characteristic of the isotope. The frequency (resonant frequency), the energy of absorption, and the intensity of measured NMR signal are proportional to the strength of the magnetic field. Nuclei of different isotopes in a substance resonate at different frequencies depending upon the local molecular geometry (bond lengths, bond angles, bonded atoms, etc.) and the local magnetic field at each nucleus. Nuclei of the same type can have slightly different resonant frequencies depending on the chemical environment. The difference between the frequency of the measured signal (NMR signal) from nuclei (in a molecule) in one sample and that (reference resonant frequency) from the same type of nuclei in a reference substance is used to obtain structural information of the molecule in a sample, or the chemical composition of the sample. This technique has applications in the study of the physical, chemical, and biological properties of matter.</ncicp:def-definition><ncicp:Definition_Review_Date>100610</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.answers.com/topic/nmr-spectroscopy (June 10, 2010), http://www.cis.rit.edu/htbooks/nmr/inside.htm (June 10, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
nuclear magnetic resonance spectroscopy
NMR spectroscopy
magnetic resonance spectroscopy
Depending on the local chemical environment, different protons in a molecule resonate at slightly different frequencies. Since this frequency shift is proportional to the strength of the magnetic field, it is converted into a field-independent dimensionless value known as the chemical shift. The chemical shift is reported as a relative measure from some reference resonance frequency. (For the nuclei1H, 13C, and 29Si, TMS (tetramethylsilane) is commonly used as a reference.) This difference between the frequency of the signal and the frequency of the reference is divided by frequency of the reference signal to give the chemical shift. The frequency shifts are extremely small in comparison to the fundamental NMR frequency. A typical frequency shift might be 100 Hz, compared to a fundamental NMR frequency of 100 MHz, so the chemical shift is generally expressed in parts per million (ppm).
By understanding different chemical environments, the chemical shift can be used to obtain some structural information about the molecule in a sample. The conversion of the raw data to this information is called assigning the spectrum. [source: http://encyclopedia.thefreedictionary.com]
When placed in a magnetic field, NMR active nuclei (such as 1H or 13C) absorb at a frequency characteristic of the isotope. The resonant frequency, energy of the absorption and the intensity of the signal are proportional to the strength of the magnetic field.
nuclear magnetic resonance spectroscopy
npo:NPO_1476
NPO_1476
NCIT:C17738
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectroscopic technique which analyzes fluorescence spectra from a sample. It involves using a beam of light, usually ultraviolet light, that excites the electrons in molecules of certain compounds and causes them to emit light of a lower energy, typically, but not necessarily, visible light.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
fluorescence spectroscopy
fluorometry
spectrofluorometry
fluorescence spectroscopy
npo:NPO_1477
NPO_1477
NCIT:C17369
<ncicp:ComplexDefinition><ncicp:def-definition>A technique to obtain the image (appearance or form) of the whole or part of a material object.</ncicp:def-definition></ncicp:ComplexDefinition>
imaging technique
imaging method
imaging technique
npo:NPO_1478
NPO_1478
NCIT:C16502
<ncicp:ComplexDefinition><ncicp:def-definition>Imaging of structural or functional patterns of organs or tissues for the purpose of diagnostic evaluation.</ncicp:def-definition></ncicp:ComplexDefinition>
diagnostic imaging
diagnostic imaging
npo:NPO_1479
NPO_1479
<ncicp:ComplexDefinition><ncicp:def-definition>An imaging technique in which waves of energy are passed through the sections of a solid object to obtain images of the internal structures of the object.</ncicp:def-definition></ncicp:ComplexDefinition>
tomography
tomography
npo:NPO_148
NPO_148
<ncicp:ComplexDefinition><ncicp:def-definition>A qualitative measure of "ionizability" which indicates that the bearer cannot be ionized to gain negative or positive charges.</ncicp:def-definition></ncicp:ComplexDefinition>
non-ionizable
non-ionizable
npo:NPO_1480
NPO_1480
NCIT:C17204
<ncicp:ComplexDefinition><ncicp:def-definition>A medical tomographic technique which uses computer to construct a three-dimensional image of the internal structures of an object from a large series of two-dimensional cross-sectional X-ray images of the object, taken around a single axis of rotation.</ncicp:def-definition></ncicp:ComplexDefinition>
computed tomography
CT
computed tomography
npo:NPO_1481
NPO_1481
NCIT:C17203
<ncicp:ComplexDefinition><ncicp:def-definition>A tomographic technique which uses radionuclides that emit single photons in the gamma energy range. The radionuclides are administered into a patient's body and the gamma rays produced by these radionuclides pass through the patient's body, which are then detected by one or more gamma cameras rotated around the patient's body. Series of two-dimensional cross-sectional images of the body, produced by this technique, can be used to create three-dimensional images by computer reconstruction.</ncicp:def-definition></ncicp:ComplexDefinition>
single photon emission computed tomography
SPECT
single photon emission computed tomography
npo:NPO_1482
NPO_1482
NCIT:C17007
<ncicp:ComplexDefinition><ncicp:def-definition>A tomography technique for measuring the gamma radiation produced by collisions of electrons and positrons (anti-electrons) within living tissue. In positron emission tomography (PET), a subject is given a dose of a positron-emitting radionuclide attached to a metabolically active substance (for example, 2-fluoro-2-deoxy-D-glucose (FDG), which is similar to a naturally occurring sugar, glucose, with the addition of a radioactive fluorine atom). When living tissue containing the positron emitter is bombarded by electrons, gamma radiation produced by collisions of electrons and positrons is detected by a scanner, revealing in fine detail the tissue location of the metabolically-active substance administered.</ncicp:def-definition></ncicp:ComplexDefinition>
positron emission tomography
PET
[definition source: NCI]
positron emission tomography
npo:NPO_1483
NPO_1483
MeSH:D008279
NCIT:C16809
<ncicp:ComplexDefinition><ncicp:def-definition>A non-invasive imaging method of creating images of internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images.</ncicp:def-definition></ncicp:ComplexDefinition>
magnetic resonance imaging
MRI
[definition: adapted from MeSH]
magnetic resonance imaging
npo:NPO_1484
NPO_1484
NCIT:C17230
<ncicp:ComplexDefinition><ncicp:def-definition>An imaging technique in which ultrasound (sound waves with frequency above the human hearing range) waves are bounced off tissues and the echoes produce a picture (sonogram).</ncicp:def-definition></ncicp:ComplexDefinition>
ultrasound imaging
ultrasound imaging
npo:NPO_1485
NPO_1485
<ncicp:ComplexDefinition><ncicp:def-definition>An oxide of titanium consisting of two oxygen atoms bonded to one titanium atom via double bonds.</ncicp:def-definition></ncicp:ComplexDefinition>
titanium dioxide
TiO2
titanium oxide
titanium(IV) oxide
titanium dioxide
npo:NPO_1486
NPO_1486
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle, which is basically composed of titanium dioxide.</ncicp:def-definition></ncicp:ComplexDefinition>
titanium oxide nanoparticle
TiO2 nanoparticle
titanium oxide nanoparticle
npo:NPO_1487
NPO_1487
<ncicp:ComplexDefinition><ncicp:def-definition>A substance which is a small representative portion of a whole material entity.</ncicp:def-definition></ncicp:ComplexDefinition>
sample
sample
npo:NPO_1488
NPO_1488
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Chemical composition of a sample determined by the type and amount of the chemical components of a sample.</ncicp:def-definition><ncicp:Definition_Review_Date>100727</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
sample composition
sample composition
npo:NPO_1489
NPO_1489
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A process which is the synthesis or preparation of a sample for analysis, testing or characterization.</ncicp:def-definition></ncicp:ComplexDefinition>
sample preparation
sample preparation
npo:NPO_149
NPO_149
<ncicp:ComplexDefinition><ncicp:def-definition>An intramolecular interaction in which two atoms share one or more electron pairs.</ncicp:def-definition></ncicp:ComplexDefinition>
covalent interaction
covalent bonding
covalent interaction
npo:NPO_1490
NPO_1490
<ncicp:ComplexDefinition><ncicp:def-definition>A property which inheres in or borne by a nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
nanoparticle property
property of nanoparticle
nanoparticle property
npo:NPO_1491
NPO_1491
<ncicp:ComplexDefinition><ncicp:def-definition>A chemical component which is identified by virtue of its molecular structure in a nanoparticle formulation.</ncicp:def-definition></ncicp:ComplexDefinition>
molecular component in nanoparticle formulation
molecular component in nanoparticle formulation
npo:NPO_1492
NPO_1492
<ncicp:ComplexDefinition><ncicp:def-definition>A role which inheres in a material entity by virtue of its ability to add/modify the properties or functions of another material entity by being associated to the latter.</ncicp:def-definition></ncicp:ComplexDefinition>
functionalizing role
functionalizing role
npo:NPO_1493
NPO_1493
<ncicp:ComplexDefinition><ncicp:def-definition>A chemical component in a nanoparticle formulation which adds/modifies functional properties or function of a nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
functionalizing agent
functionalizing agent
npo:NPO_1494
NPO_1494
<ncicp:ComplexDefinition><ncicp:def-definition>A chemical component which is identified as part of a nanoparticle formulation.</ncicp:def-definition></ncicp:ComplexDefinition>
chemical component in nanoparticle formulation
chemical component in nanoparticle formulation
npo:NPO_1495
NPO_1495
<ncicp:ComplexDefinition><ncicp:def-definition>A chemical component which is identified by virtue of its molecular structure that forms part of the basic chemical make up of a nanoparticle in a nanoparticle formulation.</ncicp:def-definition></ncicp:ComplexDefinition>
molecular component in nanoparticle
molecular component in nanoparticle
npo:NPO_1496
NPO_1496
<ncicp:ComplexDefinition><ncicp:def-definition>A chemical component which is identified as a nanoparticle based on its structure, chemical composition or function.</ncicp:def-definition></ncicp:ComplexDefinition>
nanoparticle component
nanoparticle component
npo:NPO_1497
NPO_1497
<ncicp:ComplexDefinition><ncicp:def-definition>A fiat material part identified as being the chemical make up of a material entity.</ncicp:def-definition></ncicp:ComplexDefinition>
chemical component
chemical component
npo:NPO_1498
NPO_1498
<ncicp:ComplexDefinition><ncicp:def-definition>A small organic molecule which is bonded to other similar molecules to form a polymer.</ncicp:def-definition></ncicp:ComplexDefinition>
monomer
monomer
npo:NPO_1499
NPO_1499
<ncicp:ComplexDefinition><ncicp:def-definition>A chemical component which occurs as repeated units linked together in a polymer chain.</ncicp:def-definition></ncicp:ComplexDefinition>
repeat unit
repeat unit
npo:NPO_150
NPO_150
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 77.</ncicp:def-definition></ncicp:ComplexDefinition>
iridium
iridium
npo:NPO_1500
NPO_1500
NCIT:C45306
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material entity which exists in some physical state that is identifiable as a whole at continuum length scales.</ncicp:def-definition><ncicp:Definition_Review_Date>100727</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
chemical substance by physical state
chemical substance by physical state
npo:NPO_1501
NPO_1501
<ncicp:ComplexDefinition><ncicp:def-definition>Physical state which is characteristic of a fluid.</ncicp:def-definition></ncicp:ComplexDefinition>
fluid state
fluid state
npo:NPO_1502
NPO_1502
<ncicp:ComplexDefinition><ncicp:def-definition>Physical state which is characteristic of a gas.</ncicp:def-definition></ncicp:ComplexDefinition>
gaseous state
gaseous state
npo:NPO_1503
NPO_1503
<ncicp:ComplexDefinition><ncicp:def-definition>Physical state which is characteristic of a vapor.</ncicp:def-definition></ncicp:ComplexDefinition>
vapor state
vapor state
npo:NPO_1504
NPO_1504
<ncicp:ComplexDefinition><ncicp:def-definition>Physical state which is characteristic of a liquid.</ncicp:def-definition></ncicp:ComplexDefinition>
liquid state
liquid state
npo:NPO_1505
NPO_1505
<ncicp:ComplexDefinition><ncicp:def-definition>Physical state which is characteristic of a mixture.</ncicp:def-definition></ncicp:ComplexDefinition>
state of mixture
state of mixture
npo:NPO_1506
NPO_1506
<ncicp:ComplexDefinition><ncicp:def-definition>Physical state which is characteristic of a suspension.</ncicp:def-definition></ncicp:ComplexDefinition>
state of suspension
state of suspension
npo:NPO_1507
NPO_1507
<ncicp:ComplexDefinition><ncicp:def-definition>Physical state which is characteristic of a colloid.</ncicp:def-definition></ncicp:ComplexDefinition>
colloidal state
colloidal state
npo:NPO_1508
NPO_1508
<ncicp:ComplexDefinition><ncicp:def-definition>Physical state which is characteristic of an emulsion.</ncicp:def-definition></ncicp:ComplexDefinition>
state of emulsion
state of emulsion
npo:NPO_1509
NPO_1509
<ncicp:ComplexDefinition><ncicp:def-definition>Physical state which is characteristic of a gel.</ncicp:def-definition></ncicp:ComplexDefinition>
gel state
gel state
npo:NPO_151
NPO_151
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 98.</ncicp:def-definition></ncicp:ComplexDefinition>
californium
californium
npo:NPO_1510
NPO_1510
<ncicp:ComplexDefinition><ncicp:def-definition>Physical state which is characteristic of a sol.</ncicp:def-definition></ncicp:ComplexDefinition>
state of sol
state of sol
npo:NPO_1511
NPO_1511
<ncicp:ComplexDefinition><ncicp:def-definition>Physical state which is characteristic of a sold.</ncicp:def-definition></ncicp:ComplexDefinition>
solid state
solid state
npo:NPO_1512
NPO_1512
<ncicp:ComplexDefinition><ncicp:def-definition>Physical state which is characteristic of a crystal.</ncicp:def-definition></ncicp:ComplexDefinition>
crystalline state
crystalline state
npo:NPO_1513
NPO_1513
<ncicp:ComplexDefinition><ncicp:def-definition>Physical state which is characteristic of a glass.</ncicp:def-definition></ncicp:ComplexDefinition>
glassy state
glassy state
npo:NPO_1514
NPO_1514
<ncicp:ComplexDefinition><ncicp:def-definition>Physical state which is characteristic of a granule.</ncicp:def-definition></ncicp:ComplexDefinition>
granular state
granular state
npo:NPO_1515
NPO_1515
<ncicp:ComplexDefinition><ncicp:def-definition>Physical state which is characteristic of a powder.</ncicp:def-definition></ncicp:ComplexDefinition>
powdered state
powdered state
npo:NPO_1516
NPO_1516
<ncicp:ComplexDefinition><ncicp:def-definition>A process of capturing, storing, manipulating, and displaying of images.</ncicp:def-definition></ncicp:ComplexDefinition>
imaging
imaging
npo:NPO_1517
NPO_1517
NCIT:C63536
<ncicp:ComplexDefinition><ncicp:def-definition>A process which is a detailed examination, analysis, or critical inspection of a subject designed to discover facts about it.[source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
study
study
npo:NPO_1518
NPO_1518
NCIT:C49663
<ncicp:ComplexDefinition><ncicp:def-definition>Pharmacological study of the process by which a drug (or drug-containing material) is absorbed, distributed, metabolized, and eliminated by the body.</ncicp:def-definition></ncicp:ComplexDefinition>
pharmacokinetics study
PK Study
pharmacokinetic study
pharmacokinetics
A study of what the body does to a drug or a drug-containing material (e.g., drug-loaded nanoparticle).
pharmacokinetics study
npo:NPO_1519
NPO_1519
<ncicp:ComplexDefinition><ncicp:def-definition>Study of the characteristics, effects, and uses of drugs and their interactions with living organisms.</ncicp:def-definition></ncicp:ComplexDefinition>
pharmacological study
pharmacology
pharmacological study
npo:NPO_152
NPO_152
<ncicp:ComplexDefinition><ncicp:def-definition>An element of the periodic table for which, in the atomic ground state, the highest-energy electrons occupy d-orbitals.</ncicp:def-definition></ncicp:ComplexDefinition>
d-block element
d-block element
npo:NPO_1520
NPO_1520
<ncicp:ComplexDefinition><ncicp:def-definition>Pharmacological study of the toxicity effects of a drug or drug-containing material.</ncicp:def-definition></ncicp:ComplexDefinition>
toxicology study
toxicology study
npo:NPO_1521
NPO_1521
<ncicp:ComplexDefinition><ncicp:def-definition>A property that is characteristic of the absorption, distribution, metabolism and elimination of a drug by the body.</ncicp:def-definition></ncicp:ComplexDefinition>
pharmacokinetic property
pharmacokinetic property
npo:NPO_1522
NPO_1522
NCIT:C70915
<ncicp:ComplexDefinition><ncicp:def-definition>The time required for half of an exogenous substance to be removed from either the plasma or whole or part of the body.</ncicp:def-definition></ncicp:ComplexDefinition>
elimination half life
biological half life
elimination half life
npo:NPO_1523
NPO_1523
<ncicp:ComplexDefinition><ncicp:def-definition>The area under the curve in a plot of concentration of a drug in plasma against time</ncicp:def-definition></ncicp:ComplexDefinition>
area under the plasma concentration time curve
AUC
area under curve
area under the plasma concentration time curve
npo:NPO_1524
NPO_1524
<ncicp:ComplexDefinition><ncicp:def-definition>The amount of drug in the body divided by its concentration in the blood.</ncicp:def-definition></ncicp:ComplexDefinition>
volume of distribution
Vd
volume of distribution
npo:NPO_1525
NPO_1525
<ncicp:ComplexDefinition><ncicp:def-definition>The volume of plasma from which the drug is completely removed per unit time</ncicp:def-definition></ncicp:ComplexDefinition>
drug clearance
CI
clearance
drug clearance
npo:NPO_1526
NPO_1526
<ncicp:ComplexDefinition><ncicp:def-definition>A first-order rate constant that determines the rate at which drugs are eliminated from the body.</ncicp:def-definition></ncicp:ComplexDefinition>
elimination rate constant
kel
elimination rate constant
npo:NPO_1527
NPO_1527
NCIT:C70918
<ncicp:ComplexDefinition><ncicp:def-definition>The maximum concentration of an experimental substance or drug in the plasma or a target organ after dose administration. [source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
Cmax
maximum concentration
peak concentration
Cmax
npo:NPO_1528
NPO_1528
NCIT:C70919
<ncicp:ComplexDefinition><ncicp:def-definition>The length of time it takes to reach the maximum concentration (Cmax) of an exogenous compound or drug in the plasma or a tissue after a dose is administered.[source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
Tmax
time to maximum concentration
time to peak concentation
Tmax
npo:NPO_1529
NPO_1529
<ncicp:ComplexDefinition><ncicp:def-definition>Fraction of the administered dose which reaches the systemic circulation and is available at the site of action.</ncicp:def-definition></ncicp:ComplexDefinition>
bioavailability
bioavailability
npo:NPO_153
NPO_153
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle response to external stimulus, which occurs in response to ultrasound.</ncicp:def-definition></ncicp:ComplexDefinition>
nanoparticle response to magnetic field
nanoparticle response to magnetic field
npo:NPO_1530
NPO_1530
<ncicp:ComplexDefinition><ncicp:def-definition>A parameter measured or calculated in a pharmacokinetic study.</ncicp:def-definition></ncicp:ComplexDefinition>
pharmacokinetic parameter
pharmacokinetic parameter
npo:NPO_1531
NPO_1531
<ncicp:ComplexDefinition><ncicp:def-definition>Imaging the size, shape, surface and structural properties of tumors.</ncicp:def-definition></ncicp:ComplexDefinition>
tumor imaging
imaging of tumors
tumor imaging
npo:NPO_1532
NPO_1532
<ncicp:ComplexDefinition><ncicp:def-definition>Detection of the presence or growth of tumors in the body of a human or an animal model.</ncicp:def-definition></ncicp:ComplexDefinition>
detection of tumors
tumor detection
detection of tumors
npo:NPO_1533
NPO_1533
<ncicp:ComplexDefinition><ncicp:def-definition>A chemical component in a nanoparticle formulation that is a bearer of imaging function and has payload agent role.</ncicp:def-definition></ncicp:ComplexDefinition>
therapeutic payload agent
therapeutic payload agent
npo:NPO_1534
NPO_1534
<ncicp:ComplexDefinition><ncicp:def-definition>A chemical component in a nanoparticle formulation that is a bearer of imaging function and payload agent role.</ncicp:def-definition></ncicp:ComplexDefinition>
imaging payload agent
imaging payload agent
npo:NPO_1535
NPO_1535
NCIT:C19361
<ncicp:ComplexDefinition><ncicp:def-definition>Angiogenesis which is the formation of new blood vessels that supply oxygen and nutrients to a tumor for its growth and maintenance.</ncicp:def-definition></ncicp:ComplexDefinition>
tumor angiogenesis
tumor angiogenesis
npo:NPO_1536
NPO_1536
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which is basically composed of inorganic molecular entities.</ncicp:def-definition></ncicp:ComplexDefinition>
inorganic nanoparticle
inorganic nanoparticle
npo:NPO_1537
NPO_1537
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which has superparamagnetic properties.</ncicp:def-definition></ncicp:ComplexDefinition>
superparamagnetic nanoparticle
superparamagnetic nanoparticle
npo:NPO_1538
NPO_1538
<ncicp:ComplexDefinition><ncicp:def-definition>A polymeric nanoparticle which consists of molecular components that are pH-sensitive.</ncicp:def-definition></ncicp:ComplexDefinition>
pH-sensitive polymeric nanoparticle
pH-sensitive polymeric nanoparticle
npo:NPO_1539
NPO_1539
<ncicp:ComplexDefinition><ncicp:def-definition>Diameter which inheres in a particle.</ncicp:def-definition></ncicp:ComplexDefinition>
particle diameter
particle diameter
npo:NPO_154
NPO_154
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 45.</ncicp:def-definition></ncicp:ComplexDefinition>
rhodium
rhodium
npo:NPO_1540
NPO_1540
<ncicp:ComplexDefinition><ncicp:def-definition>An oxide of metal.</ncicp:def-definition></ncicp:ComplexDefinition>
metal oxide
metal oxide
npo:NPO_1541
NPO_1541
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which is basically composed of a metal oxide.</ncicp:def-definition></ncicp:ComplexDefinition>
metal oxide nanoparticle
metal oxide nanoparticle
npo:NPO_1542
NPO_1542
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which is basically composed of zinc oxide.</ncicp:def-definition></ncicp:ComplexDefinition>
zinc oxide nanoparticle
ZnO nanoparticle
zinc oxide nanoparticle
npo:NPO_1543
NPO_1543
<ncicp:ComplexDefinition><ncicp:def-definition>An oxide of zinc.</ncicp:def-definition></ncicp:ComplexDefinition>
zinc oxide
ZnO
zinc oxide
npo:NPO_1544
NPO_1544
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which is basically composed of copper oxide.</ncicp:def-definition></ncicp:ComplexDefinition>
copper oxide nanoparticle
copper oxide nanoparticle
npo:NPO_1545
NPO_1545
<ncicp:ComplexDefinition><ncicp:def-definition>An oxide of copper.</ncicp:def-definition></ncicp:ComplexDefinition>
copper oxide
copper oxide
npo:NPO_1546
NPO_1546
<ncicp:ComplexDefinition><ncicp:def-definition>An oxide of copper having the chemical formula Cu2O.</ncicp:def-definition></ncicp:ComplexDefinition>
copper (I) oxide
Cu2O
cuprous oxide
copper (I) oxide
npo:NPO_1547
NPO_1547
<ncicp:ComplexDefinition><ncicp:def-definition>An oxide of copper having the chemical formula CuO.</ncicp:def-definition></ncicp:ComplexDefinition>
copper (II) oxide
CuO
cupric oxide
copper (II) oxide
npo:NPO_1548
NPO_1548
<ncicp:ComplexDefinition><ncicp:def-definition>An iron oxide nanoparticle which is basically composed of iron(II,III) oxide.</ncicp:def-definition></ncicp:ComplexDefinition>
iron (II,III) oxide nanoparticle
Fe3O4 nanoparticle
iron (II,III) oxide nanoparticle
npo:NPO_1549
NPO_1549
<ncicp:ComplexDefinition><ncicp:def-definition>An iron oxide nanoparticle coated with dextran.</ncicp:def-definition></ncicp:ComplexDefinition>
dextran-coated iron oxide nanoparticle
iron oxide nanoparticle coated with dextran
dextran-coated iron oxide nanoparticle
npo:NPO_1550
NPO_1550
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which is basically composed of iron (III) oxide.</ncicp:def-definition></ncicp:ComplexDefinition>
iron (III) oxide nanoparticle
Fe2O3 nanoparticle
iron (III) oxide nanoparticle
npo:NPO_1551
NPO_1551
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which has spherical shape.</ncicp:def-definition></ncicp:ComplexDefinition>
spherical nanoparticle
spherical nanoparticle
npo:NPO_1552
NPO_1552
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which is basically composed of lipid molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
lipid nanoparticle
lipid nanoparticle
npo:NPO_1553
NPO_1553
<ncicp:ComplexDefinition><ncicp:def-definition>A silica nanoparticle which has fluorescent property.</ncicp:def-definition></ncicp:ComplexDefinition>
fluorescent silica nanoparticle
fluorescent silica nanoparticle
npo:NPO_1554
NPO_1554
<ncicp:ComplexDefinition><ncicp:def-definition>A colorless water-soluble glutinous protein obtained from animal tissues such as bone and skin. (source: Word Net)</ncicp:def-definition></ncicp:ComplexDefinition>
gelatin
gelatin
npo:NPO_1555
NPO_1555
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which is basically composed of gelatin.</ncicp:def-definition></ncicp:ComplexDefinition>
gelatin nanoparticle
gelatin nanoparticle
npo:NPO_1556
NPO_1556
<ncicp:ComplexDefinition><ncicp:def-definition>A synthetic copolymer of lactic acid and glycolic acid.</ncicp:def-definition></ncicp:ComplexDefinition>
Poly(lactic-co-glycolic acid)
PLGA
PLGA polymer
drug targeted against protein of tumor cell
Poly(lactic-co-glycolic acid)
npo:NPO_1559
NPO_1559
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which is basically composed of poly(lactic-co-glycolic acid) polymer.</ncicp:def-definition></ncicp:ComplexDefinition>
PLGA nanoparticle
poly(lactic-co-glycolic acid) nanoparticle
PLGA nanoparticle
npo:NPO_156
NPO_156
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shape formed by the surface of a 3-dimensional object, having elliptical or circular plane sections.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
ellipsoidal shape
ellipsoidal
ellipsoidal shape
npo:NPO_1562
NPO_1562
<ncicp:ComplexDefinition><ncicp:def-definition>A fluorescent silica nanoparticle which has a core-shell structure.</ncicp:def-definition></ncicp:ComplexDefinition>
fluorescent core-shell silica nanoparticle
fluorescent core-shell silica nanoparticle
npo:NPO_1568
NPO_1568
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which is basically composed of hydroxyapatite.</ncicp:def-definition></ncicp:ComplexDefinition>
hydroxyapatite nanoparticle
hydroxyapatite nanoparticle
npo:NPO_1569
NPO_1569
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which is loaded with gadolinium ions.</ncicp:def-definition></ncicp:ComplexDefinition>
gadolinium-loaded nanoparticle
gadolinium-loaded nanoparticle
npo:NPO_157
NPO_157
<ncicp:ComplexDefinition><ncicp:def-definition>A nanotube which consists of a single layer or sheet of hexagonal arrays of an element or molecule, rolled into a seamless cylinder with a diameter close to 1 nanometer.</ncicp:def-definition></ncicp:ComplexDefinition>
single-walled nanotube
single-walled nanotube
npo:NPO_1570
NPO_1570
<ncicp:ComplexDefinition><ncicp:def-definition>An ion of gadolinium.</ncicp:def-definition></ncicp:ComplexDefinition>
gadolinium ion
gadolinium ion
npo:NPO_1571
NPO_1571
<ncicp:ComplexDefinition><ncicp:def-definition>A magnetic nanoparticle which consists of a coating agent composed of chitosan.</ncicp:def-definition></ncicp:ComplexDefinition>
chitosan-coated magnetic nanoparticle
chitosan-coated magnetic nanoparticle
npo:NPO_1572
NPO_1572
<ncicp:ComplexDefinition><ncicp:def-definition>A silica nanoparticle which has a core-shell structure.</ncicp:def-definition></ncicp:ComplexDefinition>
core-shell silica nanoparticle
core-shell silica nanoparticle
npo:NPO_1573
NPO_1573
NCIT:C3262
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An abnormal mass of tissue that results from uncontrolled proliferation of cells. It performs no bodily function. It may be benign (non-cancerous) or malignant (cancerous).</ncicp:def-definition></ncicp:ComplexDefinition>
tumor
neoplasm
tumor
npo:NPO_1574
NPO_1574
NCIT:C9292
<ncicp:ComplexDefinition><ncicp:def-definition>A benign or malignant tumor arising from tissues that do not include fluid areas.</ncicp:def-definition></ncicp:ComplexDefinition>
solid tumor
solid neoplasm
solid tumor
npo:NPO_1575
NPO_1575
<ncicp:ComplexDefinition><ncicp:def-definition>The pH inhering in a tumor.</ncicp:def-definition></ncicp:ComplexDefinition>
tumor pH
tumor pH
npo:NPO_1576
NPO_1576
<ncicp:ComplexDefinition><ncicp:def-definition>pH of the intracellular fluid in a cell.</ncicp:def-definition></ncicp:ComplexDefinition>
intracellular pH
pHi
intracellular pH
npo:NPO_1577
NPO_1577
MeSH: D007424
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>The fluid inside cells.</ncicp:def-definition></ncicp:ComplexDefinition>
intracellular fluid
intracellular fluid
npo:NPO_1578
NPO_1578
MeSH: D045604
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>The body fluid outside of cells.</ncicp:def-definition></ncicp:ComplexDefinition>
extracellular fluid
intercellular fluid
extracellular fluid
npo:NPO_1579
NPO_1579
<ncicp:ComplexDefinition><ncicp:def-definition>pH of the extracellular fluid.</ncicp:def-definition></ncicp:ComplexDefinition>
extracellular pH
pHe
extracellular pH
npo:NPO_1581
NPO_1581
MeSH:D042541
<ncicp:ComplexDefinition><ncicp:def-definition>The space within a cell, which contains the intracellular fluid.</ncicp:def-definition></ncicp:ComplexDefinition>
intracellular space
intracellular space
npo:NPO_1582
NPO_1582
<ncicp:ComplexDefinition><ncicp:def-definition>pH of the extracellular fluid in a tumor.</ncicp:def-definition></ncicp:ComplexDefinition>
tumor extracellular pH
tumor extracellular pH
npo:NPO_1583
NPO_1583
<ncicp:ComplexDefinition><ncicp:def-definition>Extracellular space in a tumor, which contains the tumor extracellular fluid.</ncicp:def-definition></ncicp:ComplexDefinition>
tumor extracellular space
extracellular space in tumor
extracellular space of tumor
tumor extracellular space
npo:NPO_1584
NPO_1584
<ncicp:ComplexDefinition><ncicp:def-definition>Cell of, or derived from, a tumor.</ncicp:def-definition></ncicp:ComplexDefinition>
tumor cell
tumor cell
npo:NPO_1585
NPO_1585
<ncicp:ComplexDefinition><ncicp:def-definition>Intracellular fluid inside tumor cells.</ncicp:def-definition></ncicp:ComplexDefinition>
intracellular fluid in a tumor cell
intracellular fluid in tumor cells
intracellular fluid of tumor cells
intracellular fluid in a tumor cell
npo:NPO_1586
NPO_1586
<ncicp:ComplexDefinition><ncicp:def-definition>Extracellular fluid inside a tumor.</ncicp:def-definition></ncicp:ComplexDefinition>
tumor extracellular fluid
tumor extracellular fluid
npo:NPO_1587
NPO_1587
<ncicp:ComplexDefinition><ncicp:def-definition>Intracellular space within a tumor cell.</ncicp:def-definition></ncicp:ComplexDefinition>
intracellular space of tumor cell
intracellular space of tumor cells
intracellular space of tumor cell
npo:NPO_1588
NPO_1588
<ncicp:ComplexDefinition><ncicp:def-definition>pH of the intracellular fluid in a tumor cell.</ncicp:def-definition></ncicp:ComplexDefinition>
tumor intracellular pH
tumor intracellular pH
npo:NPO_1589
NPO_1589
<ncicp:ComplexDefinition><ncicp:def-definition>The time taken for the concentration of an exogenous substance in the blood plasma to reduce by 50%</ncicp:def-definition></ncicp:ComplexDefinition>
cirulating half life
circulation half life
plasma half life
cirulating half life
npo:NPO_159
NPO_159
<ncicp:ComplexDefinition><ncicp:def-definition>A thioether linkage which is formed between a thiol and a maleimide derivative, through the covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
thioether linkage between thiol and maleimide derivative
thioether linkage between thiol and maleimide derivative
npo:NPO_1590
NPO_1590
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A circulating half life inhering in an exogenous substance (drug, nanoparticle, imaging agent) and is exhibited when it circulates in the blood plasma for a longer time compared to a reference.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
long circulating half life
long circulation half-life
long circulating half life
npo:NPO_1591
NPO_1591
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which has a circulating half life longer than that of a reference substance.</ncicp:def-definition></ncicp:ComplexDefinition>
long circulating nanoparticle
long circulating nanoparticle
npo:NPO_1592
NPO_1592
NCIT:C17067
<ncicp:ComplexDefinition><ncicp:def-definition>A receptor that is localized to the plasma membrane and may have exposure to the extracellular milieu. [source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
cell surface receptor
cell surface receptor
npo:NPO_1594
NPO_1594
<ncicp:ComplexDefinition><ncicp:def-definition>A cell surface receptor that binds to folic acid and reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells..</ncicp:def-definition></ncicp:ComplexDefinition>
folate receptor
folate-binding protein
folate receptor
npo:NPO_1595
NPO_1595
NCIT:C17664
<ncicp:ComplexDefinition><ncicp:def-definition>A cell surface receptor which binds to extracellular polypeptide molecules triggering intracellular signaling pathways that activate various cellular responses such as cell proliferation and/or differentiation. (source:NCI)</ncicp:def-definition></ncicp:ComplexDefinition>
growth factor receptor
growth factor receptor
npo:NPO_1597
NPO_1597
<ncicp:ComplexDefinition><ncicp:def-definition>A material entity [npo:MaterialEntity] that is part of a material entity but is not demarcated by any physical discontinuities.</ncicp:def-definition></ncicp:ComplexDefinition>
fiat material part
fiat material part
npo:NPO_1598
NPO_1598
<ncicp:ComplexDefinition><ncicp:def-definition>An optical imaging technique in which images are captured based on contrast provided by the fluorescence emitted from a fluorescent molecule when excited by a light of certain wavelength.</ncicp:def-definition></ncicp:ComplexDefinition>
fluorescence imaging
fluorescence imaging
npo:NPO_1599
NPO_1599
<ncicp:ComplexDefinition><ncicp:def-definition>An imaging technique, which encompasses many different techniques that use light of the UV to the NIR spectral region to visualize tissue optical characteristics imparted through absorption and scattering of light, as well as emission of fluorescence. [source: abstract from book chapter " Kai Licha, Contast Agents for Optical Imaging, vol. 222/2002, Contast Agents II, 2002."]</ncicp:def-definition></ncicp:ComplexDefinition>
optical imaging
optical imaging
npo:NPO_160
NPO_160
<ncicp:ComplexDefinition><ncicp:def-definition>A quantum dot composed of cadmium selenide.</ncicp:def-definition></ncicp:ComplexDefinition>
cadmium selenide quantum dot
CdSe quantum dot
cadmium selenide quantum dot
npo:NPO_1602
NPO_1602
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A compound or molecule which is used to label a chemical entity for purposes of identification or detection.</ncicp:def-definition></ncicp:ComplexDefinition>
labeling molecule
molecular label
labeling molecule
npo:NPO_1603
NPO_1603
<ncicp:ComplexDefinition><ncicp:def-definition>A labeling molecule or substance that is used to stain and color other material entities.</ncicp:def-definition></ncicp:ComplexDefinition>
dye
dye
npo:NPO_1604
NPO_1604
A dye which has the property to shine or glow brightly due to fluorescence.
fluorescent dye
fluorescent dye
npo:NPO_1605
NPO_1605
<ncicp:ComplexDefinition><ncicp:def-definition>A labeling role played by a molecular entity when it is used for dyeing another material entity.</ncicp:def-definition></ncicp:ComplexDefinition>
dye role
dye role
npo:NPO_1606
NPO_1606
<ncicp:ComplexDefinition><ncicp:def-definition>A material entity which is targeted by another material entity during the process of targeting.</ncicp:def-definition></ncicp:ComplexDefinition>
target
target
npo:NPO_1607
NPO_1607
<ncicp:ComplexDefinition><ncicp:def-definition>The process of directing a material entity to another material entity at a specific location.</ncicp:def-definition></ncicp:ComplexDefinition>
targeting
targeting
npo:NPO_1608
NPO_1608
<ncicp:ComplexDefinition><ncicp:def-definition>An agent role which inheres in a molecule or compound that causes the stabilization of or formation of an emulsion during the process of emulsification.</ncicp:def-definition></ncicp:ComplexDefinition>
emulsifying role
emulsifying role
npo:NPO_1609
NPO_1609
<ncicp:ComplexDefinition><ncicp:def-definition>A process in which two immiscible liquids are mixed to form an emulsion.</ncicp:def-definition></ncicp:ComplexDefinition>
emulsification
emulsification
npo:NPO_161
NPO_161
<ncicp:ComplexDefinition><ncicp:def-definition>Drug that crosses the tumor cell membrane and blocks the intracellular domain of a membrane receptor.</ncicp:def-definition></ncicp:ComplexDefinition>
drug directed against intracellular domain of membrane receptor
drug directed against intracellular domain of membrane receptor
npo:NPO_1610
NPO_1610
<ncicp:ComplexDefinition><ncicp:def-definition>A substance or a portion of a substance, which has uniform physical and chemical properties.</ncicp:def-definition></ncicp:ComplexDefinition>
phase
phase
npo:NPO_1611
NPO_1611
<ncicp:ComplexDefinition><ncicp:def-definition>A phase which is in the solid state.</ncicp:def-definition></ncicp:ComplexDefinition>
solid phase
solid phase
npo:NPO_1612
NPO_1612
<ncicp:ComplexDefinition><ncicp:def-definition>A phase which is in the liquid state.</ncicp:def-definition></ncicp:ComplexDefinition>
liquid phase
liquid phase
npo:NPO_1613
NPO_1613
<ncicp:ComplexDefinition><ncicp:def-definition>A phase which is in the gaseous state.</ncicp:def-definition></ncicp:ComplexDefinition>
gas phase
gas phase
npo:NPO_1614
NPO_1614
<ncicp:ComplexDefinition><ncicp:def-definition>A phase which is dispersed in a colloidal system.</ncicp:def-definition></ncicp:ComplexDefinition>
dispersed phase
dispersed phase
npo:NPO_1615
NPO_1615
<ncicp:ComplexDefinition><ncicp:def-definition>A phase which is medium of dispersion for the dispersed phase in a colloid.</ncicp:def-definition></ncicp:ComplexDefinition>
continuous phase
continuous phase
npo:NPO_1616
NPO_1616
<ncicp:ComplexDefinition><ncicp:def-definition>A process in which a nanoparticle is functionalized by linking it to a molecular entity that adds or modifies the properties or functions of the nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
functionalization of nanoparticle
functionalization of nanoparticle
npo:NPO_1617
NPO_1617
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A fiat material part which forms the basic structure or central part of an object.</ncicp:def-definition><ncicp:Definition_Review_Date>100610</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
core
core
npo:NPO_1618
NPO_1618
<ncicp:ComplexDefinition><ncicp:def-definition>An inhibitor role borne by a molecule produced by, and obtained from, certain living cells (especially bacteria, yeasts and moulds), or an equivalent synthetic molecule, which is biostatic or biocidal at low concentrations to some other form of life, especially pathogenic or noxious organisms.</ncicp:def-definition></ncicp:ComplexDefinition>
antibiotic role
definition based on CHEBI:22582 [antibiotic]
antibiotic role
npo:NPO_1619
NPO_1619
<ncicp:ComplexDefinition><ncicp:def-definition>A molecule role inhering in molecule, which is structurally similar to a metabolite, which competes with it or replaces it, and so prevents or reduces its normal utilization.</ncicp:def-definition></ncicp:ComplexDefinition>
antimetabolite role
definition based on CHEBI:35221 [antimetabolite]
antimetabolite role
npo:NPO_162
NPO_162
<ncicp:ComplexDefinition><ncicp:def-definition>An element of Group 1 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
Group 1 Element
Group 1 Element
npo:NPO_1622
NPO_1622
<ncicp:ComplexDefinition><ncicp:def-definition>A function inherining in a molecule that has an essential end-directed activity to bind to other molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
binding function
binding function
npo:NPO_1623
NPO_1623
NCIT:C25827
<ncicp:ComplexDefinition><ncicp:def-definition>A process which involves the formation of a covalent bond between two bases on DNA. (NCI)</ncicp:def-definition></ncicp:ComplexDefinition>
DNA crosslinking
crosslinking of DNA
DNA crosslinking
npo:NPO_1626
NPO_1626
<ncicp:ComplexDefinition><ncicp:def-definition>A function inhering in a molecule that has the end-directed activity to introduce its one or more alkyl groups to another molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
alkylating function
alkylating function
npo:NPO_1627
NPO_1627
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular role inhering in a molecule and is realized during the reversible inclusion of the molecule (or group) between the base pairs of a DNA strand.</ncicp:def-definition></ncicp:ComplexDefinition>
DNA intercalator role
DNA intercalator role
npo:NPO_1628
NPO_1628
NCIT:C40492
<ncicp:ComplexDefinition><ncicp:def-definition>DNA binding which involves insertion by covalent linkage of a molecule into the double-stranded deoxyribonucleotide polymer between the internal purine and pyrimidine base pairs stacked one on another perpendicular to the double helix axis.</ncicp:def-definition></ncicp:ComplexDefinition>
DNA intercalation
DNA intercalation
npo:NPO_163
NPO_163
<ncicp:ComplexDefinition><ncicp:def-definition>A protein that yields only amino acids when hydrolyzed. It does not contain a prosthetic group.</ncicp:def-definition></ncicp:ComplexDefinition>
simple protein
[definition source]: http://www.thefreedictionary.com, L. G. Wade Jr. Organic Chemistry 3rd Edition
simple protein
npo:NPO_1630
NPO_1630
<ncicp:ComplexDefinition><ncicp:def-definition>An inhibitor role inhering in a molecule that inhibits the metabolism or activity of a molecule that initiates a physiological response when combined with a receptor.</ncicp:def-definition></ncicp:ComplexDefinition>
antagonist role
antagonist role
npo:NPO_1633
NPO_1633
NCIT:C40643
<ncicp:ComplexDefinition><ncicp:def-definition>An inhibition which involves interference with, or restraint of, the activities of enzymatic biotransforming chemical modifications of folic acid.</ncicp:def-definition></ncicp:ComplexDefinition>
inhibition of folic acid metabolism
folic acid metabolism inhibition
inhibition of folate metabolism
inhibition of folic acid metabolism
npo:NPO_1634
NPO_1634
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that stops or reduces the activity of dihydrofolate reductase.</ncicp:def-definition></ncicp:ComplexDefinition>
inhibition of dihydrofolate reductase activity
inhibition of dihydrofolate reductase activity
npo:NPO_164
NPO_164
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 32.</ncicp:def-definition></ncicp:ComplexDefinition>
germanium
germanium
npo:NPO_1641
NPO_1641
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular role inhering in a molecule that causes the regulation of a process or the activity of another molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
regulator role
regulator role
npo:NPO_1642
NPO_1642
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A process which is performed to modify the surface of a nanoparticle using surface modifying agents.</ncicp:def-definition></ncicp:ComplexDefinition>
surface modification of nanoparticle
surface modification of nanoparticle
npo:NPO_1649
NPO_1649
<ncicp:ComplexDefinition><ncicp:def-definition>An antitumor activity which inhibits or blocks metastasis.</ncicp:def-definition></ncicp:ComplexDefinition>
inhibition of metastasis
inhibition of metastasis
npo:NPO_1656
NPO_1656
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that stops or reduces the activity of topoisomerase type I</ncicp:def-definition></ncicp:ComplexDefinition>
inhibition of DNA topoisomerase type I activity
inhibition of DNA topoisomerase type I activity
npo:NPO_1657
NPO_1657
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that stops or reduces the activity of topoisomerase type II</ncicp:def-definition></ncicp:ComplexDefinition>
inhibition of DNA topoisomerase type II activity
inhibition of DNA topoisomerase type II activity
npo:NPO_1658
NPO_1658
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that stops or reduces the activity of DNA topoisomerase.</ncicp:def-definition></ncicp:ComplexDefinition>
inhibition of DNA topoisomerase activity
inhibition of DNA topoisomerase activity
npo:NPO_1659
NPO_1659
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that stops or reduces the activity of thymidylate synthase.</ncicp:def-definition></ncicp:ComplexDefinition>
inhibition of thymidylate synthase activity
inhibition of thymidylate synthase activity
npo:NPO_166
NPO_166
<ncicp:ComplexDefinition><ncicp:def-definition>An optical imaging contrast agent, which is fluorescent, and provides contrast in images captured using fluorescence imaging techniques.</ncicp:def-definition></ncicp:ComplexDefinition>
fluorescence imaging contrast agent
contrast agent in fluorescence imaging
fluorescence imaging contrast agent
npo:NPO_1660
NPO_1660
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that stops or reduces the activity of protein kinase</ncicp:def-definition></ncicp:ComplexDefinition>
inhibition of protein kinase activity
inhibition of protein kinase activity
npo:NPO_1661
NPO_1661
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that stops or reduces the activity of protein tyrosine kinase.</ncicp:def-definition></ncicp:ComplexDefinition>
inhibition of protein tyrosine kinase activity
inhibition of protein tyrosine kinase activity
npo:NPO_1663
NPO_1663
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular role inhering in a molecule that causes the occurrence of a process.</ncicp:def-definition></ncicp:ComplexDefinition>
agent role
agent role
npo:NPO_167
NPO_167
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 101.</ncicp:def-definition></ncicp:ComplexDefinition>
mendelevium
mendelevium
npo:NPO_1680
NPO_1680
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A generically dependent continuant [snap:GenericallyDependentContinuant] which is 1) a constant in the equation of a curve that can be varied to yield a family of similar curves; or 2) any factor that defines a system and determines (or limits) its performance; or 3) a quantity (such as mean or variance) that characterizes a statistical population and that can be estimated by calculations from sample data.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>WordNet</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
parameter
parameter
npo:NPO_1681
NPO_1681
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A parameter which characterizes a wave pattern.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
wave parameter
wave parameter
npo:NPO_1682
NPO_1682
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>Amplitude of a wave pattern.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
wave amplitude
wave amplitude
npo:NPO_1683
NPO_1683
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>Frequency of a wave pattern</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
wave frequency
wave frequency
npo:NPO_1684
NPO_1684
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>Speed of a wave pattern</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
wave speed
wave speed
npo:NPO_1685
NPO_1685
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a group (whole) of multiple bearers of the same or different kinds. Two or more bearers should exist together for this quality to exist. This quality derives from an individual quality common to all the bearers in the group.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
collective quality
collective quality
npo:NPO_1686
NPO_1686
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a single bearer as a whole.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
individual quality
individual quality
npo:NPO_1687
NPO_1687
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An individual quality which inheres in a single bearer AND NOT specific to the type of bearer AND inheres in other single bearers existing by themselves independently of each other. Therefore, this quality can inhere in more than one type of single bearers.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
general individual quality
general individual quality
npo:NPO_1688
NPO_1688
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An individual quallity which inheres in a single bearer AND specific to the type of bearer.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
specific individual quality
specific individual quality
npo:NPO_1689
NPO_1689
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A general individual quality which inheres in a single bearer AND NOT specific to the type of single bearer AND the bearer needs other entities (bearers or non-bearers) to exist along with it or within it to have this quality; therefore, dependent. This quality inheres in the bearer in relation to other entities.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
dependent general individual quality
dependent general individual quality
npo:NPO_169
NPO_169
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 53.</ncicp:def-definition></ncicp:ComplexDefinition>
iodine
iodine
npo:NPO_1690
NPO_1690
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A general individual quality which inheres in a single bearer AND NOT specific to the type of single bearer AND the bearer do not need other entities (bearers or non-bearers) to exist along with it to have this quality; therefore independent.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
independent general individual quality
independent general individual quality
npo:NPO_1691
NPO_1691
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A specific individual quality which inheres in a single bearer AND specific to the type of the single bearer.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
dependent specific individual quality
dependent specific individual quality
npo:NPO_1692
NPO_1692
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A specific individual quality which inheres in a single bearer AND specific to the type of the single bearer AND the bearer do not need other entities (bearers or non-bearers) to exist along with it to have this quality; therefore, independent.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
independent specific individual quality
independent specific individual quality
npo:NPO_1693
NPO_1693
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Size of a tumor.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
tumor size
size of tumor
tumor size
npo:NPO_1694
NPO_1694
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Size of a particle.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
particle size
size of particle
particle size
npo:NPO_1695
NPO_1695
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A specific collective quality which inheres in a group of multiple bearers AND specific only to the type of bearers in the group, AND the group does not need other entities (non-bearers) to exist along with it as a whole to bear this quality.</ncicp:def-definition><ncicp:Definition_Review_Date>101029</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
independent specific collective quality
independent specific collective quality
npo:NPO_1696
NPO_1696
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A specific collective quality which inheres in a group of multiple bearers, AND specific only to the type of bearers in the group, AND the group needs other bearers to exist along with it as a whole to bear this quality.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
dependent specific collective quality
dependent specific collective quality
npo:NPO_1697
NPO_1697
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A polydispersity inhering in a collection of objects based on size.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
size distribution
size distribution
npo:NPO_1698
NPO_1698
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A polydispersity inhering in polymers based on molecular weight.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
molecular weight distribution
molecular weight distribution
npo:NPO_1699
NPO_1699
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A size distribution inhering in particles.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
particle size distribution
particle size distribution
npo:NPO_1700
NPO_1700
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An in vitro assay performed to analyze the effect of a nanoparticle formulation or other substance on plasma coagulation.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>NCL assay protocol - ITA-12 (v 1.0)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
coagulation assay
blood clotting assay
blood coagulation assay
coagulation assay
npo:NPO_1701
NPO_1701
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A coagulation assay which is performed to measure the time it takes for the blood plasma to coagulate in a sample when the coagulation is activated by prothrombin.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
prothrombin time assay
PT assay
prothrombin time assay
npo:NPO_1702
NPO_1702
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A coagulation assay which is performed to measure the time it takes for the blood plasma to coagulate when the coagulation is activated by thrombin.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
thrombin time assay
TCT assay
TT assay
thrombin assay
thrombin clotting time assay
thrombin time assay
npo:NPO_1703
NPO_1703
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A coagulation assay which is performed to measure the time it takes for the plasma to coagulate when the coagulation is activated by partial thromboplastin.</ncicp:def-definition></ncicp:ComplexDefinition>
activated partial thromboplastin time assay
APTT assay
activated partial thromboplastin time assay
npo:NPO_1704
NPO_1704
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A coagulation assay which is performed to measure the time taken for the plasma to coagulate in a sample when the coagulation is activated by reptilase.</ncicp:def-definition></ncicp:ComplexDefinition>
reptilase time assay
RT assay
reptilase time assay
npo:NPO_1705
NPO_1705
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An in vitro assay which is performed using purified or crude biochemical reagents in the absence of cells.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>NCGC assay guidelines (http://ncgc.nih.gov/guidance/glossary.html)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
biochemical assay
biochemical assay
npo:NPO_1706
NPO_1706
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An in vitro assay in which the analyzed sample contains live cells.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>NCGC assay guidelines (http://www.ncgc.nih.gov/guidance/glossary.html)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
cell-based assay
cell-based assay
npo:NPO_1707
NPO_1707
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A cell-based assay which is performed to test the cytotoxic effects of a nanoparticle formulation or other substance.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
cytoxicity assay
cytoxicity assay
npo:NPO_1708
NPO_1708
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A cytotoxicity assay which is performed to study the cytoxic effects of nanoparticle formulation or other substance on cell viability.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
cell viability assay
cell viability assay
npo:NPO_1709
NPO_1709
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A cell viability assay which is performed by assessing the activity of lactate dehydrogenase (a cytoplasmic enzyme) released into the cell culture supernatant, when the plasma membrane is damaged. LDH release is used as a marker of dead cells.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
LDH release assay
LDH assay
lactate dehydrogenase assay
LDH release assay
25
npo:NPO_171
NPO_171
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 25.</ncicp:def-definition></ncicp:ComplexDefinition>
manganese atom
manganese atom
npo:NPO_1710
NPO_1710
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectroscopic technique which measures the intensity of electromagnetic radiation absorbed by a molecular entity or a substance at different wavelengths or frequencies.</ncicp:def-definition><ncicp:Definition_Review_Date>100610</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
absorption spectroscopy
absorption spectroscopy
npo:NPO_1711
NPO_1711
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectroscopic technique which measures the intensity of electromagnetic radiation emitted by a molecular entity or a substance at different wavelengths or frequencies.</ncicp:def-definition><ncicp:Definition_Review_Date>100610</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
emission spectroscopy
emission spectroscopy
npo:NPO_1712
NPO_1712
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectroscopic technique which measures the intensity of light scattered from a substance at certain wavelengths, incident angles, and polarization angles.</ncicp:def-definition><ncicp:Definition_Review_Date>100527</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
light scattering spectroscopy
light scattering spectroscopy
npo:NPO_1713
NPO_1713
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A disturbance which carries energy radiated from a source and which propagates through space (vacuum or space occupied by a medium) and time.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>wikipedia (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
wave
wave
npo:NPO_1714
NPO_1714
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A wave which does not require a medium to travel, and hence can travel through vacuum. The wave consists of vibrating electric and magnetic fields that move at right angles to each other and to the direction of wave motion. The electric and magnetic fields are produced by the acceleration of charged particles.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://library.thinkquest.org/10796/ch8/ch8.htm (June 3, 2010), http://www.physicsclassroom.com/Class/waves/u10l1c.cfm (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
electromagnetic wave
E-M wave
EM wave
Electromagnetic waves are characterized by any of the three physical properties: frequency, wavelength or quantum (photon) energy. Frequency of a wave is defined as the ratio of the speed of light (in vacuum) to wavelength of the wave. The quantum energy is defined as the product of the Planck's constant and the wave frequency. The range of all possible frequencies or wavelengths or energies of an electromagnetic wave is called the electromagnetic spectrum. (reference: wikipedia)
electromagnetic wave
npo:NPO_1715
NPO_1715
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A wave which requires a medium (e.g., air, water, solid) to travel for transmitting energy from one location to another, with no net displacement of the particles in the medium.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://library.thinkquest.org/10796/ch8/ch8.htm (June 3, 2010); http://www.visionlearning.com (June 8, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
mechanical wave
mechanical wave
npo:NPO_1716
NPO_1716
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths shorter than 0.001 nm, frequencies greater than 100 EHz (1 EHz = 10^18 Hz), and energies greater than 1.24 MeV.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://hyperphysics.phy-astr.gsu.edu/hbase/ems3.html#c5 (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
gamma-ray wave
gamma-ray wave
npo:NPO_1717
NPO_1717
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths between 10 nm and 0.001 nm, frequencies between 30 PHz and 100 EHz (1 PHz - 10^15 Hz, 1 EHz = 10^18 Hz), and energies between 124 eV and 1.24 MeV. An X-ray wave has wavelength shorter than that of an ultraviolet wave and longer than that of a gamma-ray wave</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://hyperphysics.phy-astr.gsu.edu/hbase/ems3.html#c4 (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
x-ray wave
x-ray wave
npo:NPO_1718
NPO_1718
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths between 400 nm and 10 nm, frequencies between 300 THz and 750 THz (1 THz = 10^12 Hz), and energies between 3.1 eV and 124 eV. An ultraviolet wave has a wavelength shorter than that of a visible light wave, but longer than that of an x-ray wave.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://hyperphysics.phy-astr.gsu.edu/hbase/ems3.html#c4 (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
ultraviolet wave
UV wave
ultraviolet wave
npo:NPO_1719
NPO_1719
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths between 750 nm and 400 nm, frequencies between 400 THz and 750 THz (1 THz = 10^12 Hz), and energies between 1.65 eV and 3.1 eV. A visible light wave has a wavelength longer than that of an ultraviolet wave, and shorter than that of an infrared wave.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://hyperphysics.phy-astr.gsu.edu/hbase/ems3.html#c2 (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
visible light wave
visible light wave
npo:NPO_1720
NPO_1720
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths between 1 mm and 750 nm, frequencies between 300 GHz and 40 THz (1 GHz = 10^9 Hz, 1 THz = 10^12 Hz), and energies between 0.00124 eV and 1.65 eV. An infrared wave has a wavelength longer than that of a visible light wave, and shorter than that of a microwave.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://hyperphysics.phy-astr.gsu.edu/hbase/ems3.html#c1 (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
infrared wave
IR wave
infrared wave
npo:NPO_1721
NPO_1721
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An infrared wave which has wavelengths between 1 mm and 10 um, frequencies between 300 GHz and 30 THz (1 GHz = 10^9 Hz, 1 THz = 10^12 Hz), and energies between 0.00124 eV and 0.124 eV.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
far-infrared wave
FIR wave
far-infrared wave
npo:NPO_1722
NPO_1722
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An infrared wave which has wavelengths between 10 um and 2.5 um, frequencies between 30 THz and 120 THz (1 THz = 10^12 Hz), and energies between 0.124 eV and 0.5 eV.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
mid-infrared wave
MIR wave
mid-infrared wave
npo:NPO_1723
NPO_1723
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An infrared wave which has wavelengths between 2.5 um and 750 nm, frequencies between 120 THz and 400 THz (1 THz = 10^12 Hz), and energies between 0.5 eV and 1.65 eV.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
near-infrared wave
NIR wave
near-infrared wave
npo:NPO_1724
NPO_1724
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths between 30 cm and 1 mm, frequencies between 1 GHz and 300 GHz (1 GHz = 10^9 Hz), and energies between 4.1 ueV and 1.24 meV. A microwave has a wavelength longer than that of an infrared wave, but shorter than that of a radiowave.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://physics.info/em-spectrum (June 3, 2010), wikipedia (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
microwave
microwave
npo:NPO_1725
NPO_1725
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths longer than 30 cm, frequencies less than 1 GHz (1 GHz = 10^9 Hz). and energies less than 4.1 ueV.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
radiowave
radiowave
npo:NPO_1726
NPO_1726
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A mechanical wave in which the particles of the medium move back and forth in a direction perpendicular to the direction in which the wave moves and transports energy.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
transverse wave
transverse wave
npo:NPO_1727
NPO_1727
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A mechanical wave in which particles of the medium move back and forth in a direction parallel to the direction in which the wave moves and transports energy.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
longitudinal wave
longitudinal wave
npo:NPO_1728
NPO_1728
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A longitudinal wave which transports energy (sound energy) produced by a vibrating object through a medium in which the back and forth motions of the particles result in regions of high (compression) and low pressure (rarefactions) in the medium.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
sound wave
accoustic wave
sound wave
npo:NPO_1729
NPO_1729
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A sound wave which is transmitted through air causing a sinusoidal pressure variation in the air at a frequency within the human audible range, i.e., approximately between 20 Hz and 20 kHz.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
audible sound wave
audible sound wave
npo:NPO_173
NPO_173
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 7.</ncicp:def-definition></ncicp:ComplexDefinition>
nitrogen
nitrogen
npo:NPO_1730
NPO_1730
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A sound wave which has frequencies above 20 kHz (upper limit of the human audible frequency range).</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
ultrasound wave
ultrasonic wave
ultrasound wave
npo:NPO_1731
NPO_1731
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A process in which energy emitted by a material source travels in the form of waves, rays, or sub-atomic particles, through a material medium or through vacuum, to be ultimately absorbed by another material.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
radiation
radiation
npo:NPO_1732
NPO_1732
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A radiation which consists of waves of energy associated with electric and magnetic fields produced by the acceleration of electric charges.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
electromagnetic radiation
E-M radiation
EMR
electromagnetic radiation
npo:NPO_1733
NPO_1733
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which consists of waves with frequencies greater than 100 EHz (1 EHz = 10^18 Hz), and with wavelengths shorter than 0.001 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
gamma radiation
gamma ray
gamma ray radiation
gamma radiation
npo:NPO_1734
NPO_1734
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which consists of waves with frequencies between 30 PHz and 100 EHz (1 PHz = 10^15 Hz, 1 EHz = 10^18 Hz), and with wavelengths between 10 nm and 0.001 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
x-ray radiation
x-ray
x-ray radiation
npo:NPO_1735
NPO_1735
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which consists of waves with frequencies between 300 THz and 750 THz (1 THz = 10^12 Hz), and with wavelengths between 400 nm and 10 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
ultraviolet radiation
UV radiation
ultraviolet radiation
npo:NPO_1736
NPO_1736
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which can be detected by the human eye, and it consists of waves with frequencies between 400 THz and 750 THz (1 THz = 10^12 Hz), and with wavelengths between 750 nm and 400 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
visible light radiation
visible light radiation
npo:NPO_1737
NPO_1737
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which consists of waves with frequencies between 300 GHz and 400 THz (1 GHz = 10^9 Hz, 1 THz = 10^12 Hz), and with wavelengths between 1 mm and 750 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
infrared radation
infrared radation
npo:NPO_1738
NPO_1738
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An infrared radiation which consists of waves with frequencies between 300 GHz and 30 THz (1 GHz = 10^9 Hz, 1 THz = 10^12 Hz), and with wavelengths between 1 mm and 10 um.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
far-infrared radiation
FIR radiation
far-infrared radiation
npo:NPO_1739
NPO_1739
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An infrared radiation which consists of waves with frequencies between 30 THz and 120 THz (1THz = 10^12 Hz ), and with wavelengths between 10 um and 2.5 um.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
mid-infrared radiation
MIR radiation
mid-infrared radiation
npo:NPO_174
NPO_174
<ncicp:ComplexDefinition><ncicp:def-definition>A group which is a specific atom or group of atoms attached to the carbon backbone of an organic molecule, and it is responsible for characteristic reactions of the molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
functional group
characteristic group
Each functional group has its characteristic reactivity, which may be modified by its position within the molecule or by the presence of other neighbouring functional groups. (source: Functional Group Chemistry by James R. Hanson and Eddie Abel, published by Wiley, John & Sons, Incorporate 2002)
functional group
npo:NPO_1740
NPO_1740
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An infrared radiation which consists of waves with frequencies between 120 THz and 400 THz (1 THz = 10^12 Hz), and with wavelengths between 2.5 um and 750 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
near-infrared radiation
NIR radiation
near-infrared radiation
npo:NPO_1741
NPO_1741
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which consists of waves with frequencies between 1 GHz and 300 GHz (1 GHz = 10^9 Hz), and with wavelengths between 30 cm and 1 mm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
microwave radiation
microwave radiation
npo:NPO_1742
NPO_1742
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which consists of waves with frequencies less than 1 GHz (1 GHz = 10^9 Hz), and with wavelengths longer than 30 cm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
radiowave radiation
radiowave radiation
npo:NPO_1743
NPO_1743
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A radiation which consists of waves that transmit sound energy produced from a source, and the waves travel through a medium.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
sound radiation
sound radiation
npo:NPO_1744
NPO_1744
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A sound radiation which consists of waves that transmit sound energy at frequencies above 20 kHz (upper limit of the human audible frequency range)</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
ultrasound radiation
ultrasound radiation
npo:NPO_1745
NPO_1745
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity which is the capacity to do work or to exert force over a distance.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
energy
energy
npo:NPO_1746
NPO_1746
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Energy associated with a moving object by virtue of its motion.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
kinetic energy
kinetic energy
npo:NPO_1747
NPO_1747
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Energy which is stored in an object, and that can be converted into some form of kinetic energy.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
potential energy
stored energy
potential energy
npo:NPO_1748
NPO_1748
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Kinetic energy which is associated with moving electrons.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
electrical energy
electricity
electrical energy
npo:NPO_1749
NPO_1749
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Kinetic energy which is associated with randomnly moving atoms or molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
heat energy
heat
thermal energy
heat energy
npo:NPO_175
NPO_175
<ncicp:ComplexDefinition><ncicp:def-definition>An arylthioether linkage which is formed between a thiol and a fluorobenzene derivative, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
arylthioether linkage between thiol and fluorobenzene derivative
arylthioether linkage between thiol and fluorobenzene derivative
npo:NPO_1750
NPO_1750
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Kinetic energy which is associated with the motion of electromagnetic waves produced by the acceleration of electric charges.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
light energy
electromagnetic energy
light
light energy
npo:NPO_1751
NPO_1751
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Light energy which is associated with the motion of infrared waves.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
infrared light energy
infrared light
infrared light energy
npo:NPO_1752
NPO_1752
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Light energy which is associated with the motion of far-infrared waves.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
far-infrared light energy
far-infrared light
far-infrared light energy
npo:NPO_1753
NPO_1753
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Infrared light energy which is asscoated with the motion of mid-infrared waves.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
mid-infrared light energy
mid-infrared light
mid-infrared light energy
npo:NPO_1754
NPO_1754
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Infrared light energy which is associated with the motion of near-infrared light waves.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
near-infrared light energy
near-infrared light
near-infrared light energy
npo:NPO_1755
NPO_1755
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Light energy which is associated with the motion of ultraviolet waves.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
ultraviolet light energy
UV light
ultraviolet light
ultraviolet light energy
npo:NPO_1756
NPO_1756
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Light energy which is associated with the motion of visible light waves.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
visible light energy
visible light
visible light energy
npo:NPO_1757
NPO_1757
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Kinetic energy which is produced by the vibrations of an object, and transported by disturbances (sound waves) traveling through a medium.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
sound energy
sound
sound energy
npo:NPO_1758
NPO_1758
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Sound energy which is carried by waves (audible sound waves) traveling at frequencies (between 20 Hz and 20 kHz) that can be detected by the human ear.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
audible sound energy
audible sound
audible sound energy
npo:NPO_1759
NPO_1759
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Sound energy which is carried by waves (ultrasound waves) that travel at frequencies above the human audible range (above 20 kHz).</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
ultrasound energy
ultrasonic sound
ultrasound
ultrasound energy
npo:NPO_176
NPO_176
<ncicp:ComplexDefinition><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by near-infrared light.</ncicp:def-definition></ncicp:ComplexDefinition>
stimulus of near-infrared light
stimulus of near-infrared light
npo:NPO_1760
NPO_1760
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Potential energy which is stored in the chemical bonds of molecules, and which is released as heat energy in a chemical reaction.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
chemical energy
chemical energy
npo:NPO_1761
NPO_1761
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Potential energy which is stored in interactions between the particles in the atomic nucleus.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
nuclear energy
nuclear energy
npo:NPO_1762
NPO_1762
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A technique which is used for counting cells.</ncicp:def-definition><ncicp:Definition_Review_Date>100614</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
cell counting technique
cell counting technique
npo:NPO_1763
NPO_1763
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A cell counting technique which uses fluorescence for counting the cells.</ncicp:def-definition><ncicp:Definition_Review_Date>100614</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
fluorescent cell counting technique
fluorescent cell counting technique
npo:NPO_1764
NPO_1764
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A fluorescence microscopic technique which uses scanning laser light to excite fluorescent dyes within a thick sample, such as a biofilm. The image is collected in two dimensions and several images can be combined in an image stack to produce a cross sectional image through a sample or to create a three-dimensional rendering of the sample. This technique is particularly useful for imaging the positioning of biological structures within a three-dimensional space.</ncicp:def-definition><ncicp:Definition_Review_Date>100614</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.nature.com/nrd/journal/v2/n2/glossary/nrd1008_glossary.html</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
confocal laser scanning microscopy
CLSM
confocal laser scanning microscopy
npo:NPO_1765
NPO_1765
NCIT: C78807
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which consists of a thick glass slide that has a chamber with a defined volume, etched with a precisely ruled grid and is used to quantify cells or cell-sized particles in suspension.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>NCI Thesaurus</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
hemocytometer
hemocytometer
npo:NPO_1766
NPO_1766
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is used to perform dynamic light scattering technique.</ncicp:def-definition><ncicp:Definition_Review_Date>100616</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
dynamic light scattering instrument
DLS instrument
dynamic light scattering instrument
npo:NPO_1767
NPO_1767
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is used to perform phase analysis light scattering technique.</ncicp:def-definition><ncicp:Definition_Review_Date>100617</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
phase analysis light scattering instrument
PALS instrument
phase analysis light scattering instrument
npo:NPO_1768
NPO_1768
NCIT: C78860
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A transmission electron microscope which is designed to allow the scientist to both introduce various gases into and change the temperature of the specimen/sample environment. Reactions of the sample with its environment can then be directly recorded.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:def-source>NCI</ncicp:def-source><ncicp:attr>NCIT</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
environmental transmission electron microscope
EC-TEM
ETEM
environmental cell-transmission electron microscope
environmental transmission electron microscope
npo:NPO_1769
NPO_1769
NCIT: C78806
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is used to count and sort microscopic particles suspended in a buffer. This instrument consists of a flow cell, at least one lamp or laser, a variable number of emission detectors or photomultipliers, a system that converts analog signals to digital, and a computer to run the system and collect and analyze the data output.</ncicp:def-definition><ncicp:Definition_Review_Date>100616</ncicp:Definition_Review_Date><ncicp:def-source>NCI</ncicp:def-source><ncicp:attr>NCIT</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
flow cytometer
flow cytometer
npo:NPO_177
NPO_177
<ncicp:ComplexDefinition><ncicp:def-definition>An element whose physical and chemical characteristics vary progressively within a series.</ncicp:def-definition></ncicp:ComplexDefinition>
series element
series element
npo:NPO_1770
NPO_1770
NCIT: C80370
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is used to determine the mass of a sample with a high degree of precision.</ncicp:def-definition><ncicp:Definition_Review_Date>100616</ncicp:Definition_Review_Date><ncicp:def-source>NCI</ncicp:def-source><ncicp:attr>NCIT</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
analytical balance
analytical balance
npo:NPO_1771
NPO_1771
NCIT: C62330
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>An instrument which is used to measure changes in the electrical resistance of an electrolyte solution produced by suspended nonconductive particles. Changes in resistance determine both the concentraion and size distribution of the particles.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
coulter counter
particle count analyzer
particle count and size analyzer
particle counter
particle size analyzer
coulter counter
npo:NPO_1772
NPO_1772
NCIT:C80371
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is used to measure the intensity of visible light.</ncicp:def-definition><ncicp:Definition_Review_Date>100617</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>NCIT</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
photometer
photometer
npo:NPO_1773
NPO_1773
NCIT: C62333
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A photometer which measures the intensity of visible light as a function of wavelength.</ncicp:def-definition><ncicp:Definition_Review_Date>100617</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
spectrophotometer
spectrometer
spectrophotometer
npo:NPO_1774
NPO_1774
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectrometer which is used to determine the energy of photoelectrons emitted from the core orbitals of the elements within a few nm from the surface of a material, by irradiating the material surface with soft monochromatic X-rays.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
X-ray photoelectron spectrometer
X-ray photoelectron spectrometer
npo:NPO_1775
NPO_1775
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>An instrument which is used to measure zeta potential.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
zeta potential analyzer
zeta potential analyzer
npo:NPO_1776
NPO_1776
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is used to perform capillary electrophoresis.</ncicp:def-definition><ncicp:Definition_Review_Date>100617</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
capillary electrophoresis instrument
capillary electrophoresis instrument
npo:NPO_1777
NPO_1777
NCIT: C78805
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A spectrometer which focuss high energy electromagnetic radiation toward a sample and measures the X-rays emitted from the sample.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
energy dispersive spectrometer
EDS
EDX
energy dispersive X-ray spectrometer
energy dispersive spectrometer
npo:NPO_1778
NPO_1778
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is a column in which gel particles in bead form are packed to form a separation bed through which a solution containing molecules /particles and an eluant (a buffer solution) are passed for separating the molecules/particles according to differences in their sizes.</ncicp:def-definition><ncicp:Definition_Review_Date>100616</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.scribd.com/doc/6941835/gel-filtration (June 16, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
gel filtration column
gel filtration column
npo:NPO_1779
NPO_1779
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A value which is given for a variable or parameter in a data record.</ncicp:def-definition><ncicp:Definition_Review_Date>100618</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
datum value
datum value
npo:NPO_178
NPO_178
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 109.</ncicp:def-definition></ncicp:ComplexDefinition>
meitnerium
meitnerium
npo:NPO_1780
NPO_1780
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A generically dependent continuant which can be represented using different types of numerals, and which is used for counting, measuring or computing a quantity, or for identification.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
number
number
npo:NPO_1781
NPO_1781
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A generically dependent continuant which is used for or regarded as representing something else.</ncicp:def-definition><ncicp:Definition_Review_Date>100618</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://dictionary.reference.com/browse/symbol (June 18, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
symbol
symbol
npo:NPO_1782
NPO_1782
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A symbol which represents a string of letters and numbers.</ncicp:def-definition><ncicp:Definition_Review_Date>100618</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
alphanumeral
alphanumeral
npo:NPO_1783
NPO_1783
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A symbol which denotes or represents a number in a language.</ncicp:def-definition><ncicp:Definition_Review_Date>100618</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
numeral
numeral
npo:NPO_1784
NPO_1784
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A numeral which is one of the following: 1, 2, 3, 4, 5, 6, 7, 8, 9, and 0.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
arabic numeral
arabic numeral
npo:NPO_1785
NPO_1785
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A numeral which denotes numbers as words used in the english language.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
english numeral
english numeral
npo:NPO_1786
NPO_1786
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An english numeral which is basic in form, and which is used in counting and expressing how many objects are referred to. (Examples: one, two, three, one hundred, etc.)</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.sil.org/linguistics/GlossaryOfLinguisticTerms/WhatIsACardinalNumeral.htm (June 21, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
cardinal numeral
cardinal numeral
npo:NPO_1787
NPO_1787
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An english numeral which expresses a group of the number specified. (examples: by the dozen, in pairs)</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.sil.org/linguistics/GlossaryOfLinguisticTerms/WhatIsADistributiveNumeral.htm (June 21, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
distributive numeral
distributive numeral
npo:NPO_1788
NPO_1788
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An english numeral which expresses how many fold or how many times. (Examples: once, twice, thrice, ...)</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.sil.org/linguistics/GlossaryOfLinguisticTerms/WhatIsMultiplicativeNumeral.htm (June 21, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
multiplicative numeral
multiplicative numeral
npo:NPO_1789
NPO_1789
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An english numeral which is used to designate positions in a sequence. (Examples: first, second, third, etc.)</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
ordinal numeral
ordinal numeral
npo:NPO_179
NPO_179
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An atom is the smallest particle that retains all the chemical properties of a given element.</ncicp:def-definition></ncicp:ComplexDefinition>
atom
atom
npo:NPO_1790
NPO_1790
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An english numeral which is used to express a fraction. (Examples: one-half, one-third, etc.)</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
partitive numeral
partitive numeral
npo:NPO_1791
NPO_1791
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A number which is denoted by alphanumerals.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
alphanumeric number
alphanumeric number
npo:NPO_1792
NPO_1792
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A number which is denoted by arabic numerals.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
numeric number
numeric number
npo:NPO_1793
NPO_1793
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A datum value which is expressed in numbers, and which is measured, assigned, or computed.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
quantitative value
quantitative value
npo:NPO_1794
NPO_1794
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A datum value which is non-numerical measure or estimate of something.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
qualitative value
qualitative value
npo:NPO_1795
NPO_1795
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value which is obtained by computations or calculations.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
computed value
calculated value
computed value
npo:NPO_1796
NPO_1796
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value which is obtained by counting.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
counted value
counted value
npo:NPO_1797
NPO_1797
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A computed value which is a summary of the individual quantitative variable values for the statistical units in a specific group (study domains).</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://stats.oecd.org/glossary</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
statistical measure
statistical measure
npo:NPO_1798
NPO_1798
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A statistical measure which describes the spread in a data set of numerical values for a quantitative variable.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
measure of variability
measure of variability
npo:NPO_1799
NPO_1799
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A statistical measure which is a meaure of the middle or expected value of a data set.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
measure of central tendency
measure of central tendency
npo:NPO_180
NPO_180
<ncicp:ComplexDefinition><ncicp:def-definition>A fiat part of a dendrimer.</ncicp:def-definition></ncicp:ComplexDefinition>
fiat dendrimer part
fiat dendrimer part
npo:NPO_1800
NPO_1800
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of central tendency which is the sum of all the numerical values in a data set divided by the numer of numerical values.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
mean
average
average value
mean value
mean
npo:NPO_1801
NPO_1801
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of central tendency which is the middle value of a distribution of numerical values.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
median
median
npo:NPO_1802
NPO_1802
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of central tendency which is the most frequently occurring value in a set of numerical values.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
mode
mode
npo:NPO_1803
NPO_1803
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of variability which is the average of the square of the difference between the numerical values and the mean in a data set.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
variance
variance
npo:NPO_1804
NPO_1804
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of variability which is the square root of variance.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
standard deviation
standard deviation
npo:NPO_1805
NPO_1805
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value which is measured using an instrument.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
measured value
measured value
npo:NPO_1806
NPO_1806
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of temperature which is measured or calculated.</ncicp:def-definition><ncicp:Definition_Review_Date>100622</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
temperature value
temperature value
npo:NPO_1807
NPO_1807
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of size which is measured or calculated.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
size value
size value
npo:NPO_1808
NPO_1808
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Composition which refers to the types and amounts of chemical components in the core of a material entity.</ncicp:def-definition><ncicp:Definition_Review_Date>100624</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
core composition
core composition
npo:NPO_1809
NPO_1809
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A solid substance which has a conductivity between that of an insulator and that of a conductor.</ncicp:def-definition><ncicp:Definition_Review_Date>100622</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
semiconductor
semiconductor
npo:NPO_181
NPO_181
<ncicp:ComplexDefinition><ncicp:def-definition>A heterobifunctional crosslinker, which has a carbonyl-reactive group at one end and a sulfhydryl-reactive group at the other end.</ncicp:def-definition></ncicp:ComplexDefinition>
carbonyl-reactive and sulfhydryl-reactive crosslinker
carbonyl-reactive and sulfhydryl-reactive crosslinker
npo:NPO_1810
NPO_1810
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality which indicates the presence of a hole or empty space within a material entity.</ncicp:def-definition><ncicp:Definition_Review_Date>100624</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
hollow
hollow
npo:NPO_1811
NPO_1811
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Composition which refers to the types and amounts of chemical components on the surface of a material entity.</ncicp:def-definition><ncicp:Definition_Review_Date>100624</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
surface composition
surface composition
npo:NPO_1812
NPO_1812
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electric charge which is the net charge present on the surface of a material entity.</ncicp:def-definition><ncicp:Definition_Review_Date>100624</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
surface charge
surface charge
npo:NPO_1813
NPO_1813
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of body weight which is measured.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
body weight value
body weight value
npo:NPO_1814
NPO_1814
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A quantitative value of pH which is measured or calculated.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
pH value
pH value
npo:NPO_1815
NPO_1815
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of zeta potential which is measured or calculated.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
zeta potential value
zeta potential value
npo:NPO_1816
NPO_1816
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of cell viability which is measured or calculated in percentage units.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
percent cell viability
percent cell viability
npo:NPO_1817
NPO_1817
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of time which is measured or calculated.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
time value
time value
npo:NPO_1818
NPO_1818
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A temporal interval which is the time during which a process continues to occur.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
duration
duration
npo:NPO_1819
NPO_1819
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>Duration in which a material entity is in contact with or exposed to something.</ncicp:def-definition><ncicp:Definition_Review_Date>100624</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
time of exposure
time of exposure
npo:NPO_182
NPO_182
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 103.</ncicp:def-definition></ncicp:ComplexDefinition>
lawrencium
lawrencium
npo:NPO_1820
NPO_1820
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A dimensionless concentration notation which denotes the amount of a given substance in a total amount of 1000, 000,000 regardless of the units of measure used as long as they are the same or 1 part in10^[9].</ncicp:def-definition><ncicp:Definition_Review_Date>100625</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
parts per billion
ppb
parts per billion
npo:NPO_1821
NPO_1821
CHEBI:226739
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A carboxylic acid which is composed of six carbon atoms and a sulfhydryl group at the sixth carbon atom.</ncicp:def-definition><ncicp:Definition_Review_Date>100625</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
6-mercapto-hexanoic acid
OC(=O)CCCCCS
6-MHA
6-mercaptohexanoic acid
?-mercaptohexonic acid
6-mercapto-hexanoic acid
npo:NPO_1822
NPO_1822
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A mean of all the individual particle size values in a collection of particles.</ncicp:def-definition><ncicp:Definition_Review_Date>100702</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
mean particle size
average particle size
mean particle size
npo:NPO_1823
NPO_1823
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>Chemical composition of a coating layer on a material surface.</ncicp:def-definition><ncicp:Definition_Review_Date>100702</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
coat composition
coating composition
coat composition
npo:NPO_1824
NPO_1824
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Chemical composition of a material layer surrounding the core.</ncicp:def-definition><ncicp:Definition_Review_Date>100702</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
shell composition
shell composition
npo:NPO_1825
NPO_1825
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A sample which is tested for determining its physical, chemical, and functional properties in an experiment.</ncicp:def-definition><ncicp:Definition_Review_Date>100714</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
test sample
experimental sample
test sample
npo:NPO_1826
NPO_1826
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical component in a nanoparticle formulation, which is a nanoparticle or a molecule that is conjugated to another nanoparticle or molecule in the same formulation.</ncicp:def-definition><ncicp:Definition_Review_Date>100714</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
conjugated component
conjugated component
npo:NPO_1827
NPO_1827
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical component in nanoparticle formulation which is a nanoparticle or a molecule that is fully enclosed within a nanoparticle's site that is fully bounded by the particle's constituting material.</ncicp:def-definition><ncicp:Definition_Review_Date>100714</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
encapsulated component
encapsulated component
npo:NPO_1828
NPO_1828
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical component in nanoparticle formulation, which is a molecule or a nanoparticle that is trapped due to non-covalent interactions in a nanoparticle's site that is partially bounded by the particle's constituting material.</ncicp:def-definition><ncicp:Definition_Review_Date>100714</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
entrapped component
entrapped component
npo:NPO_1829
NPO_1829
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A mean value calculated from the polydispersity indices of particle or polymeric samples of the same type.</ncicp:def-definition><ncicp:Definition_Review_Date>100727</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
mean polydispersity index
mean polydispersity index
npo:NPO_183
NPO_183
<ncicp:ComplexDefinition><ncicp:def-definition>A nanosensor which is defined as a nanometer-scale measurement device that consists of a biologically or chemically sensitive layer, such as an immobilized receptor, antibody, or nucleic acid, that is covalently attached to an optical transducer. In the case of a receptor-based nanosensor, an interaction between the immobilized receptor and its substrate - the molecule it binds to - produces a perturbation that the optical transducer converts to an electrical signal via laser-induced fluorescence.</ncicp:def-definition></ncicp:ComplexDefinition>
fiber-optic nanosensor
fiber-optic nanosensor
npo:NPO_1830
NPO_1830
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Concentration of particles dispersed in a medium or in solution.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
particle concentration
particle concentration
npo:NPO_1832
NPO_1832
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A substance which dissolves in another substance (solvent) to form a solution.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
solute
solute
npo:NPO_1833
NPO_1833
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A role inhering in a certain amount of a compound, which is realized when it is dissolved in a solvent.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
solute role
solute role
npo:NPO_1834
NPO_1834
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A role which inheres in a liquid compound, and it is realized when the liquid dissolves another substance (solute).</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
solvent role
solvent role
npo:NPO_1835
NPO_1835
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A liquid mixture which is a homogenous mixture formed by dissolving a substance (solute) in a liquid (solvent).</ncicp:def-definition></ncicp:ComplexDefinition>
solution
solution
npo:NPO_1836
NPO_1836
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An aqueous solution which consists of a weak acid and its conjugate base or a weak base and its conjugate acid; and which resists any changes in its pH when a small amount of strong acid or base is added to it.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://en.wikipedia.org/wiki/Buffer_solution ( July 28, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
buffer solution
buffer solution
npo:NPO_1837
NPO_1837
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A solution which contains water as the solvent.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
aqueous solution
aqueous solution
npo:NPO_1838
NPO_1838
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality which inheres in a substance by virtue of it containing water as a solvent or a medium.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
aqueous
aqueous
npo:NPO_1839
NPO_1839
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A substance which is added to an acidic or basic solution, and then modifies its pH value to a new one and then maintains that pH.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
buffer
buffer
npo:NPO_184
NPO_184
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 99.</ncicp:def-definition></ncicp:ComplexDefinition>
einsteinium
einsteinium
npo:NPO_1840
NPO_1840
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>An aqueous solution which contains more hydrogen ions than hydroxyl ions.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
acid solution
acidic solution
acid solution
npo:NPO_1841
NPO_1841
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An aqueous solution which contains more hydroxyl ions than hydrogen ions.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
alkaline solution
basic solution
alkaline solution
npo:NPO_1842
NPO_1842
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An aqueous solution of sodium chloride.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
saline
saline solution
saline
npo:NPO_1843
NPO_1843
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A salt whcih is composed of sodium and chloride ions.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
sodium chloride
NaCl
sodium chloride
npo:NPO_1844
NPO_1844
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a solution by virtue of it having the same solute concentration as another solution.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
isotonic
isotonic
npo:NPO_1845
NPO_1845
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A saline solution which has the same NaCl concentration as blood.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
isotonic saline
isotonic saline solution
isotonic saline
npo:NPO_1846
NPO_1846
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An isotonic saline solution which contains phosphate buffer.</ncicp:def-definition></ncicp:ComplexDefinition>
phosphate buffer saline
PBS
phosphate buffer saline solution
phosphate buffer saline
npo:NPO_1847
NPO_1847
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Water which has been purified by distillation.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://encyclopedia.thefreedictionary.com (July 28, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
distilled water
distilled water
npo:NPO_1848
NPO_1848
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Water which has been purified by ion exchange process, and lacks cations from sodium, calcium, iron, copper and anions such as chloride and bromide.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://encyclopedia.thefreedictionary.com (July 28, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
deionized water
deionized water
npo:NPO_1849
NPO_1849
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of polydispersity index, which is calculated.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
polydispersity index value
PDI value
polydispersity index value
npo:NPO_185
NPO_185
<ncicp:ComplexDefinition><ncicp:def-definition>An iodoacetyl compound is an organic compound which is characterized by the presence of an iodoacetyl group. It has the structure R-C(=O)-CH2-I, where R denotes an organic group or hydrogen atom.</ncicp:def-definition></ncicp:ComplexDefinition>
iodoacetyl compound
iodoacetyl derivative
iodoacetyl compound
npo:NPO_1850
NPO_1850
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity which is defined as the ratio of the speed of light in vacuum to that in a substance. It is a measure of the speed of light in the substance.</ncicp:def-definition></ncicp:ComplexDefinition>
refractive index
index of refraction
refractive index
npo:NPO_1851
NPO_1851
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of refractive index.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
refractive index value
refractive index value
npo:NPO_1852
NPO_1852
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity inhering in a fluid, which is defined as the fluid's resistance to flow.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
viscosity
viscosity
npo:NPO_1853
NPO_1853
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A fluid which can hold other substances in solution or in suspension.</ncicp:def-definition><ncicp:Definition_Review_Date>100729</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
medium
medium
npo:NPO_1854
NPO_1854
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A medium which contains water.</ncicp:def-definition><ncicp:Definition_Review_Date>100729</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
aqueous medum
aqueous medum
npo:NPO_1855
NPO_1855
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A medium which is used as a solvent to form a solution.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
solvent medium
solvent medium
npo:NPO_1856
NPO_1856
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A liquid medium which is used to suspend particles.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
suspending medium
dispersing medium
suspending medium
npo:NPO_1857
NPO_1857
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of viscosity, which is measured or calculatd.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
viscosity value
viscosity value
npo:NPO_1858
NPO_1858
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A unit of measure, which is a standard measure of the resistance of a fluid to deformation.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
viscosity unit
viscosity unit
npo:NPO_1859
NPO_1859
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A viscosity unit in standard international system, which is equal to 1 pascal second</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
pascal second
N s/m^[2]
Pa s
kg / (m s)
pascal second
npo:NPO_186
NPO_186
<ncicp:ComplexDefinition><ncicp:def-definition>A quantum dot composed of gold element</ncicp:def-definition></ncicp:ComplexDefinition>
gold quantum dot
Au quantum dot
gold quantum dot
npo:NPO_1860
NPO_1860
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A core which is composed of organic molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>100817</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
organic core
organic core
npo:NPO_1861
NPO_1861
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A core which is composed of inorganic molecular entities.</ncicp:def-definition><ncicp:Definition_Review_Date>100817</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
inorganic core
inorganic core
npo:NPO_1862
NPO_1862
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An organic core which is composed of polymers.</ncicp:def-definition><ncicp:Definition_Review_Date>100817</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
polymeric core
polymer core
polymeric core
npo:NPO_1863
NPO_1863
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An inorganic core which is composed of one or more metals.</ncicp:def-definition><ncicp:Definition_Review_Date>100817</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
metallic core
metal core
metallic core
npo:NPO_1864
NPO_1864
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An inorganic core which is composed of metal oxide.</ncicp:def-definition><ncicp:Definition_Review_Date>100817</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
metal oxide core
metal oxide core
npo:NPO_1865
NPO_1865
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An inorganic core which is composed of silica (silicon dioxide).</ncicp:def-definition><ncicp:Definition_Review_Date>100817</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
silica core
silica core
npo:NPO_1866
NPO_1866
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An inorganic core which has semiconducting property.</ncicp:def-definition><ncicp:Definition_Review_Date>101007</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
semiconducting core
semiconducting core
npo:NPO_1867
NPO_1867
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>An electrical conductivity which is intermediate between that of an insulator and a conductor.</ncicp:def-definition><ncicp:Definition_Review_Date>101007</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
semiconductivity
semiconductivity
npo:NPO_1868
NPO_1868
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A shell which is made of inorganic material.</ncicp:def-definition><ncicp:Definition_Review_Date>101007</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
inorganic shell
inorganic shell
npo:NPO_1869
NPO_1869
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shell which is made of organic material.</ncicp:def-definition><ncicp:Definition_Review_Date>101007</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
organic shell
organic shell
11
npo:NPO_187
NPO_187
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 11.</ncicp:def-definition></ncicp:ComplexDefinition>
sodium atom
sodium atom
npo:NPO_1870
NPO_1870
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shell which is composed of a polymer.</ncicp:def-definition><ncicp:Definition_Review_Date>101010</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
polymeric shell
polymeric shell
npo:NPO_1871
NPO_1871
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shell which is composed of a metal or a metal-based compound.</ncicp:def-definition><ncicp:Definition_Review_Date>101010</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
metallic shell
metallic shell
npo:NPO_1872
NPO_1872
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shell which is composed of metal oxide.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
metal oxide shell
metal oxide shell
npo:NPO_1873
NPO_1873
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shel which is composed of silica.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
silica shell
silica shell
npo:NPO_1874
NPO_1874
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shell which exhibits semiconductivity.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
semiconductive shell
semiconducting shell
semiconductive shell
npo:NPO_1875
NPO_1875
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An inorganic core which exhibits superparamagnetism.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
superparamagnetic core
superparamagnetic core
npo:NPO_1876
NPO_1876
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A superparamagnetic core which is composed of iron oxide.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
superparamagnetic iron oxide core
superparamagnetic iron oxide core
npo:NPO_1877
NPO_1877
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material boundary which is positively charged due to the presence of cations on the material boundary.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
cationic surface
cationic surface
npo:NPO_1878
NPO_1878
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material boundary which is negatively charged due to the presence of anions on the material boundary.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
anionic surface
anionic surface
npo:NPO_1879
NPO_1879
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material boundary which exhibits affinity towards water molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
hydrophilic surface
hydrophilic surface
npo:NPO_188
NPO_188
<ncicp:ComplexDefinition><ncicp:def-definition>Drug affecting the structure, function and synthesis of DNA in tumor cells</ncicp:def-definition></ncicp:ComplexDefinition>
drug directed against tumor DNA
drug directed against tumor DNA
npo:NPO_1880
NPO_1880
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material boundary which exhibits poor affinity to water molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
hydrophobic surface
hydrophobic surface
npo:NPO_1881
NPO_1881
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a molecule that is covalently attached to the surfce of the nanoparticle and that adds a functionality to the nanoparticle.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
surface-functionalized nanoparticle
surface-functionalized nanoparticle
npo:NPO_1882
NPO_1882
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A functionalizing role which inheres in a material entity that is covalently attached to the surface of a nanoparticle.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
surface functionalizing role
nanoparticle surface functionalizing role
surface functionalizing role
npo:NPO_1883
NPO_1883
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A functionalization of nanoparticle which is performed on the surface of the nanoparticle.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
surface functionalization of nanoparticle
functionalization of nanoparticle surface
surface functionalization of nanoparticle
npo:NPO_1884
NPO_1884
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A chemical component in nanoparticle formulation which is used to functionalize the surface of a nanoparticle.</ncicp:def-definition><ncicp:Definition_Review_Date>101027</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
surface functionalizing agent
surface functionalizing agent
npo:NPO_1885
NPO_1885
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A nanoparticle which has a surface that is chemically modified by the attachment of a small molecule or by the replacement of a surface functional group with a different type of functional group.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
surface modified nanoparticle
surface modified nanoparticle
npo:NPO_1886
NPO_1886
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A nanoparticle which dissolves in water.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
water-soluble nanoparticle
water soluble nanoparticle
water-soluble nanoparticle
npo:NPO_1887
NPO_1887
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A coat which has affinity to water molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
hydrophilic coat
water-soluble coat
hydrophilic coat
npo:NPO_1888
NPO_1888
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A molecular component in a nanoparticle, which forms part or whole of nanoparticle's core.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
core component
core component
npo:NPO_1889
NPO_1889
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A molecular component in a nanoparticle, which forms part or whole of the nanoparticle's shell.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
shell component
shell component
57
npo:NPO_189
NPO_189
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 57.</ncicp:def-definition></ncicp:ComplexDefinition>
lanthanum atom
lanthanum atom
npo:NPO_1890
NPO_1890
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A molecular component in a nanoparticle, which forms part or whole of the coat on a nanoparticle.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
coat component
coat component
npo:NPO_1891
NPO_1891
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A lipid membrane which is one (lipid) molecule thick.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
lipid monolayer
lipid monolayer
npo:NPO_1892
NPO_1892
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A nanoparticle which is basically composed of silver element.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
silver nanoparticle
Ag nanoparticle
silver nanoparticle
npo:NPO_1893
NPO_1893
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A metal nanoparticle which is composed of two types of metals.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
bimetallic nanoparticle
bimetallic nanoparticle
npo:NPO_1894
NPO_1894
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A functional group which is located on the surface of an object (.e.g., nanoparticle).</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
surface group
surface group
npo:NPO_1895
NPO_1895
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material entity which is a minute portion of matter.</ncicp:def-definition></ncicp:ComplexDefinition>
particle
particle
npo:NPO_1896
NPO_1896
<ncicp:ComplexDefinition><ncicp:def-definition>A particle which is originally obtained from its source.</ncicp:def-definition><ncicp:attr>PAS71 (draft 2.0) 2010-09-21</ncicp:attr></ncicp:ComplexDefinition>
primary particle
primary particle
npo:NPO_1897
NPO_1897
<ncicp:ComplexDefinition><ncicp:def-definition>A particle which is composed of two or more primary particles held together by covalent bonds or by weak forces like Van der Waals forces or by simply physical entanglements.</ncicp:def-definition><ncicp:attr>PAS 71 (draft 2.0) 2010-09-21</ncicp:attr></ncicp:ComplexDefinition>
secondary particle
secondary particle
npo:NPO_1898
NPO_1898
<ncicp:ComplexDefinition><ncicp:def-definition>A level of measureable information about a variable.</ncicp:def-definition></ncicp:ComplexDefinition>
scale of measurement
measurement scale
scale of measurement
npo:NPO_1899
NPO_1899
<ncicp:ComplexDefinition><ncicp:def-definition>An interval scale is a measurement scale in which a certain distance along the scale means the same thing no matter where on the scale you are, but where "0" on the scale does not represent the absence of the thing being measured.</ncicp:def-definition><ncicp:attr>http://www.statistics.com/resources/glossary/i/intscale.php (</ncicp:attr></ncicp:ComplexDefinition>
interval scale of measurement
interval measurement scale
interval scale
interval scale of measurement
npo:NPO_190
NPO_190
<ncicp:ComplexDefinition><ncicp:def-definition>An element of the periodic table for which, in the atomic ground state, the highest-energy electrons occupy g-orbitals.</ncicp:def-definition></ncicp:ComplexDefinition>
g-block element
g-block element
npo:NPO_1900
NPO_1900
<ncicp:ComplexDefinition><ncicp:def-definition>An interval scale of measurement which provides numerical values for temperature in the range, 0 to 100, where a value of zero corresponds to the melting point of water, while a value of 100 corresponds to the boiling point of water.</ncicp:def-definition></ncicp:ComplexDefinition>
Celsius scale
Celsius scale
npo:NPO_1901
NPO_1901
<ncicp:ComplexDefinition><ncicp:def-definition>An interval scale of measurement, which provides numerical values for temperature in the range, 32 to 212, where a value of 32 corresponds to the melting point of water, while a value of 100 corresponds to the boiling point of water.</ncicp:def-definition></ncicp:ComplexDefinition>
Fahrenheit scale
Fahrenheit scale
npo:NPO_1902
NPO_1902
<ncicp:ComplexDefinition><ncicp:def-definition>A ratio scale of measurement, which provides numerical values for temperature starting from the lowest attainable value equal to zero (absolute zero).</ncicp:def-definition></ncicp:ComplexDefinition>
Kelvin scale
Kelvin scale
npo:NPO_1903
NPO_1903
<ncicp:ComplexDefinition><ncicp:def-definition>A scale of measurement in which a certain distance along the scale means the same thing no matter where on the scale you are, and where "0" on the scale represents the absence of the thing being measured.</ncicp:def-definition><ncicp:attr>http://www.statistics.com/resources/glossary/r/ratioscale.php (Dec. 6, 2010)</ncicp:attr></ncicp:ComplexDefinition>
ratio scale of measurement
ratio measurement scale
ratio scale
ratio scale of measurement
npo:NPO_1904
NPO_1904
<ncicp:ComplexDefinition><ncicp:def-definition>A scale of measurement, which provides a list of categories to which objects can be classified. The data so classified are termed categorical data.</ncicp:def-definition><ncicp:attr>http://www.statistics.com/resources/glossary/n/nomscale.php (Dec. 6, 2010)</ncicp:attr></ncicp:ComplexDefinition>
nominal scale of measurement
nominal measurement scale
nominal scale
nominal scale of measurement
npo:NPO_1905
NPO_1905
<ncicp:ComplexDefinition><ncicp:def-definition>A scale of measurement, which assigns values to objects based on their ranking with respect to one another.</ncicp:def-definition><ncicp:attr>http://www.statistics.com/resources/glossary/o/ordscale.php (Dec. 6, 2010)</ncicp:attr></ncicp:ComplexDefinition>
ordinal scale of measurement
ordinal measurement scale
ordinal scale
ordinal scale of measurement
npo:NPO_1906
NPO_1906
<ncicp:ComplexDefinition><ncicp:def-definition>An interval scale of measurement, which provides log transformed values of a measured variable.</ncicp:def-definition></ncicp:ComplexDefinition>
logarithmic scale
logarithmic scale
npo:NPO_1907
NPO_1907
<ncicp:ComplexDefinition><ncicp:def-definition>A logarithmic scale which represents log (to the base 10) values of the concentration of hydrogen ions in aqueous solutions.</ncicp:def-definition></ncicp:ComplexDefinition>
pH scale
pH scale
npo:NPO_1908
NPO_1908
<ncicp:ComplexDefinition><ncicp:def-definition>An interval scale of measurement which provides a range of values between 1 nm and a few hundred nm.</ncicp:def-definition></ncicp:ComplexDefinition>
nanoscale
nanoscale
npo:NPO_1909
NPO_1909
<ncicp:ComplexDefinition><ncicp:def-definition>A nanomaterial which is designed for a specific purpose or function.</ncicp:def-definition><ncicp:attr>ISO/TS 80004-1</ncicp:attr></ncicp:ComplexDefinition>
engineered nanomaterial
engineered nanomaterial
npo:NPO_191
NPO_191
<ncicp:ComplexDefinition><ncicp:def-definition>A disposition which inheres in a material entity that can be decomposed by living organisms.</ncicp:def-definition></ncicp:ComplexDefinition>
biodegradable
e.g., biodegradable nanoparticle
biodegradable
npo:NPO_1910
NPO_1910
<ncicp:ComplexDefinition><ncicp:def-definition>A nanomaterial which has an internal nanostructure or surface nanostructure.</ncicp:def-definition><ncicp:attr>ISO/TS 80004-1</ncicp:attr></ncicp:ComplexDefinition>
nanostructured material
nanostructured material
npo:NPO_1911
NPO_1911
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>defintion</ncicp:def-definition></ncicp:ComplexDefinition>
MTT assay
MTT cytoxicity assay
MTT assay
npo:NPO_1912
NPO_1912
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A physical assay which is used to measure the size of a particle or molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
size assay
size assay
npo:NPO_1913
NPO_1913
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>The generation number of a dendrimer.</ncicp:def-definition></ncicp:ComplexDefinition>
dendrimer generation
generation number
dendrimer generation
npo:NPO_1914
NPO_1914
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>The size of a particle or molecule in an aqueous solution.</ncicp:def-definition></ncicp:ComplexDefinition>
hydrodynamic size
hydrodynamic size
npo:NPO_1915
NPO_1915
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>The hydrodynamic size which is the diameter of a particle or molecule (approximated as a sphere) in an aqueous solution.</ncicp:def-definition></ncicp:ComplexDefinition>
hydrodynamic diameter
hydrodynamic diameter
npo:NPO_1916
NPO_1916
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition to be added</ncicp:def-definition></ncicp:ComplexDefinition>
z-average
z-average
npo:NPO_1917
NPO_1917
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition to be added</ncicp:def-definition></ncicp:ComplexDefinition>
diaminobutane
diaminobutane
npo:NPO_1918
NPO_1918
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition to be added.</ncicp:def-definition></ncicp:ComplexDefinition>
tris(hydroxymethyl)aminomethane
tris(hydroxymethyl)aminomethane
npo:NPO_1919
NPO_1919
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition to be added.</ncicp:def-definition></ncicp:ComplexDefinition>
poly(amidoamine)
poly(amidoamine)
npo:NPO_192
NPO_192
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular role inhering in a protein molecule by virtue of the protein's function.</ncicp:def-definition></ncicp:ComplexDefinition>
protein role
protein role
npo:NPO_1920
NPO_1920
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition to be entered.</ncicp:def-definition></ncicp:ComplexDefinition>
magnevist
magnevist
npo:NPO_1921
NPO_1921
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A technique which describes the way how a material is synthesized.</ncicp:def-definition></ncicp:ComplexDefinition>
material synthesis technique
method of synthesis
synthesis method
synthesis technique
material synthesis technique
npo:NPO_1922
NPO_1922
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material synthesis technique in which chemical reactions require the use of a solution.</ncicp:def-definition></ncicp:ComplexDefinition>
solution-based chemistry technique
solution based chemistry method
solution-based chemistry
solution-based chemistry technique
npo:NPO_1923
NPO_1923
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A solution-based chemistry technique in which substances are crystallized from high temperature aqueous solutions at high vapor pressures.</ncicp:def-definition><ncicp:attr>http://en.wikipedia.org/wiki/Hydrothermal_synthesis</ncicp:attr></ncicp:ComplexDefinition>
hydrothermal method
hydrothermal technique
hydrothermal method
npo:NPO_1924
NPO_1924
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A solution-based chemistry technique for dispersing two or more immiscible liquids as micron-sized droplets by shaking, stirring or homogenising the mixture.</ncicp:def-definition><ncicp:attr>http://www.rsc.org/publishing/journals/prospect/ontology.asp?id=CMO:0.0002150$MSID=b916837k</ncicp:attr></ncicp:ComplexDefinition>
micro-emulsion method
micro-emulsion technique
micro-emulsion method
npo:NPO_1925
NPO_1925
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A solution-based chemical technique which is used to synthesize a semi-solid material (gel) from a stable suspension of colloidal solid particles or polymers in a liquid (sol).</ncicp:def-definition><ncicp:attr>http://cheminfo.chemi.muni.cz/materials/InorgMater/sol_gel.pdf</ncicp:attr></ncicp:ComplexDefinition>
sol-gel chemical process
sol-gel chemical process
npo:NPO_1926
NPO_1926
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Solvent displacement method is a solution-based chemistry technique in which a polymer (and drug) is first dissolved in a water-miscible solvent of intermediate polarity to form an organic solution that is then slowly added drop wise into a stirred aqueous solution containing a stabilizer or surfactant. As a result, the solvent diffuses between the water interface and organic solvent leading to instantaneous formation of colloidal nanoparticles. After the solvent is evaporated, the colloidal nanoparticles solidify to form nanoparticles of small sizes with narrow size distribution.</ncicp:def-definition><ncicp:attr>Handbook of materials for nanomedicine. Vladimir Torchilin, Mansoor M. Amiji</ncicp:attr></ncicp:ComplexDefinition>
solvent displacement method
solvent displacement method
npo:NPO_1927
NPO_1927
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition [to do]</ncicp:def-definition></ncicp:ComplexDefinition>
sonochemical method
sonochemical method
npo:NPO_1928
NPO_1928
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition [to do]</ncicp:def-definition></ncicp:ComplexDefinition>
template-assisted solution-based synthesis
template-assisted solution-based synthesis
npo:NPO_1929
NPO_1929
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A synthesis technique which involves the layer-by-layer deposition of individual atoms from a material source (solid, liquid, vapor or gas), onto the surface of a material (substrate).</ncicp:def-definition></ncicp:ComplexDefinition>
thin film deposition technique
thin film deposition technique
npo:NPO_193
NPO_193
<ncicp:ComplexDefinition><ncicp:def-definition>A quantum dot composed of zinc sulfide.</ncicp:def-definition></ncicp:ComplexDefinition>
zinc sulfide quantum dot
ZnS quantum dot
zinc sulfide quantum dot
npo:NPO_1930
NPO_1930
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A thin film deposition technique in which one or more volatile precursors react and/or decompose on the surface of the substrate.</ncicp:def-definition></ncicp:ComplexDefinition>
chemical vapor deposition
CVD
CVD technique
chemical vapor deposition technique
chemical vapor deposition
npo:NPO_1931
NPO_1931
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical vapor deposition technique in which gaseous precursors chemically react with a surface in a sequential manner.</ncicp:def-definition></ncicp:ComplexDefinition>
atomic layer deposition
atomic layer deposition technique
atomic layer deposition
npo:NPO_1932
NPO_1932
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical vapor deposition technique in which metal organic compounds in gas phase (at moderate pressures) react to form epitaxial layers of material on the surface of the substrate.</ncicp:def-definition></ncicp:ComplexDefinition>
metal-organic chemical vapor deposition
MOCVD
MOVPE
OMVPE
metalorganic vapor phase epitaxy
organometallic vapor phase epitaxy
metal-organic chemical vapor deposition
npo:NPO_1933
NPO_1933
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical vapor deposition technique in which gaseous precursors react when a plasma of the gases is created by RF (radio frequency) or DC discharge between two electrodes.</ncicp:def-definition></ncicp:ComplexDefinition>
plasma-enhanced chemical vapor deposition
PECVD
plasma-enhanced chemical vapor deposition
npo:NPO_1934
NPO_1934
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical vapor deposition in which the substrate is heated.</ncicp:def-definition></ncicp:ComplexDefinition>
thermal chemical vapor deposition
TCVD
rapid thermal CVD
rapid thermal chemical vapor deposition
thermal CVD
thermal chemical vapor deposition
npo:NPO_1935
NPO_1935
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A thin film deposition technique in which atoms from the surface of a solid material are vaporized by physical methods (e.g. by bombarding the solid surface with an energetic ion beam, laser beam, or electron beam), and then transported for deposition on the surface of the substrate. The deposition process takes place in under low pressure or vacuum conditions.</ncicp:def-definition></ncicp:ComplexDefinition>
physical vapor deposition
PVD
physical vapor deposition technique
physical vapor deposition
npo:NPO_1936
NPO_1936
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A physical vapor deposition technique in whcih the source material is vaporized by irradiating the target surface of the source material by a pulsed laser beam.</ncicp:def-definition></ncicp:ComplexDefinition>
pulsed laser deposition
pulsed laser deposition technique
pulsed laser deposition
npo:NPO_1937
NPO_1937
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A physical vapor deposition technique in which atoms from the surface of a solid material are vaporized by bombarding the surface with energetic particles (e.g., accelerated ions).</ncicp:def-definition></ncicp:ComplexDefinition>
sputter deposition
sputter deposition technique
sputter deposition
npo:NPO_1938
NPO_1938
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A type of sputter deposition where a magnetron is used to direct the flow of high energy electrons for the sputtering process. A magnetron is a vacuum tube in which the electrons generated from a heated cathode flows under the control of an applied magnetic field.</ncicp:def-definition></ncicp:ComplexDefinition>
magnetron sputtering
magnetron sputtering
npo:NPO_1939
NPO_1939
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A physical vapor deposition technique in which the source material is evaporated in vacuum, and the vaporized material condenses on the surface of the substrate.</ncicp:def-definition></ncicp:ComplexDefinition>
thermal evaporation
thermal evaporation method
thermal evaporation technique
thermal evaporation
npo:NPO_1940
NPO_1940
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A physical vapor deposition in which a target anode is bombarded with an electron beam given off by a charged tungsten filament under high vacuum.</ncicp:def-definition><ncicp:attr>http://en.wikipedia.org/wiki/Electron_beam_physical_vapor_deposition</ncicp:attr></ncicp:ComplexDefinition>
electron beam physical vapor deposition
EBPVD
electron beam physical vapor deposition
npo:NPO_1941
NPO_1941
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A thermal evaporation technique in which the evaporated atoms in high or ultra-high vacuum do not interact with each other until they reach the surface of the substrate. The deposition occurs at a slow rate to allow controlled growth of a monocrystalline film on a monocrystalline substrate.</ncicp:def-definition></ncicp:ComplexDefinition>
molecular beam epitaxy
molecular beam epitaxy
npo:NPO_1942
NPO_1942
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A thermal evaporation technique in which heat is generated using electric conductors carrying current.</ncicp:def-definition></ncicp:ComplexDefinition>
resistive heating
resistive heating
npo:NPO_1943
NPO_1943
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A thermal evaporation technique in which the target surface of the source material is heated by an electromagnetic field induced by a RF (radio frequency) signal.</ncicp:def-definition></ncicp:ComplexDefinition>
RF-induction technique
RF-induction technique
npo:NPO_1944
NPO_1944
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A process which is conducted or occurs during the synthesis of a material.</ncicp:def-definition></ncicp:ComplexDefinition>
synthesis part
synthesis part
npo:NPO_1945
NPO_1945
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A process which is conducted during synthesis.</ncicp:def-definition></ncicp:ComplexDefinition>
macroscopic synthesis part
macroscopic synthesis part
npo:NPO_1946
NPO_1946
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition: To Do</ncicp:def-definition></ncicp:ComplexDefinition>
precipitation
precipitation
npo:NPO_1947
NPO_1947
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A solution-based chemistry technique which enables the precipitation of soluble substances.</ncicp:def-definition></ncicp:ComplexDefinition>
co-precipitation
co-precipitation
npo:NPO_1948
NPO_1948
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition: To Do</ncicp:def-definition></ncicp:ComplexDefinition>
purification
purification
npo:NPO_1949
NPO_1949
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition: To Do</ncicp:def-definition></ncicp:ComplexDefinition>
quenching
quenching
npo:NPO_195
NPO_195
<ncicp:ComplexDefinition><ncicp:def-definition>A fiat material part formed by chemically linking or associating two or more material entities (molecular entities, groups, nanomaterials) or parts thereof by molecular forces.</ncicp:def-definition></ncicp:ComplexDefinition>
linkage
association
chemical association
linkage
npo:NPO_1950
NPO_1950
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition: To Do</ncicp:def-definition></ncicp:ComplexDefinition>
rinsing
rinsing
npo:NPO_1951
NPO_1951
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition: To Do</ncicp:def-definition></ncicp:ComplexDefinition>
shaking
shaking
npo:NPO_1952
NPO_1952
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition: To Do</ncicp:def-definition></ncicp:ComplexDefinition>
vortex shaking
vortex shaking
npo:NPO_1953
NPO_1953
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition: To Do</ncicp:def-definition></ncicp:ComplexDefinition>
centrifugation
centrifugation
npo:NPO_1954
NPO_1954
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition: To Do</ncicp:def-definition></ncicp:ComplexDefinition>
cooling
cooling
npo:NPO_1955
NPO_1955
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition: To Do</ncicp:def-definition></ncicp:ComplexDefinition>
dissolution
dissolution
npo:NPO_1956
NPO_1956
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition: To Do</ncicp:def-definition></ncicp:ComplexDefinition>
drying
drying
npo:NPO_1957
NPO_1957
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition: To Do</ncicp:def-definition></ncicp:ComplexDefinition>
freeze-drying
freeze-drying
npo:NPO_1958
NPO_1958
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition: To Do</ncicp:def-definition></ncicp:ComplexDefinition>
heating
heating
npo:NPO_1959
NPO_1959
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition: To Do</ncicp:def-definition></ncicp:ComplexDefinition>
homogenization
homogenization
npo:NPO_196
NPO_196
<ncicp:ComplexDefinition><ncicp:def-definition>An element of Group 5 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
Group 5 Element
vanadium group element
Group 5 Element
npo:NPO_1960
NPO_1960
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition: To Do</ncicp:def-definition></ncicp:ComplexDefinition>
mixing
mixing
npo:NPO_1961
NPO_1961
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition: To Do</ncicp:def-definition></ncicp:ComplexDefinition>
sonication
sonication
npo:NPO_1962
NPO_1962
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A process in which the surface of a material is coated.</ncicp:def-definition></ncicp:ComplexDefinition>
surface coating
surface coating
npo:NPO_1963
NPO_1963
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition: To Do</ncicp:def-definition></ncicp:ComplexDefinition>
washing
washing
npo:NPO_1964
NPO_1964
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A process which takes place during synthesis of a sample at the microscopic level.</ncicp:def-definition></ncicp:ComplexDefinition>
microscopic synthesis part
microscopic synthesis part
npo:NPO_1965
NPO_1965
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A process in which the surface of a particle is coated using polyethylene glycol (PEG).</ncicp:def-definition></ncicp:ComplexDefinition>
PEGylation
PEGylation
npo:NPO_1966
NPO_1966
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition: To Do</ncicp:def-definition></ncicp:ComplexDefinition>
agglomeration
agglomeration
npo:NPO_1967
NPO_1967
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition: To Do</ncicp:def-definition></ncicp:ComplexDefinition>
aggregation
aggregation
npo:NPO_1968
NPO_1968
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition: To Do</ncicp:def-definition></ncicp:ComplexDefinition>
crosslinking
crosslinking
npo:NPO_1969
NPO_1969
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition: To Do</ncicp:def-definition></ncicp:ComplexDefinition>
dispersion
dispersion
npo:NPO_197
NPO_197
<ncicp:ComplexDefinition><ncicp:def-definition>A nanocage composed of gold element.</ncicp:def-definition></ncicp:ComplexDefinition>
gold nanocage
Gold nanocages, some 40 nanometers in diameter can be made by replacing the silver atoms of silver nanotubes.
gold nanocage
npo:NPO_1970
NPO_1970
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>definition: To Do</ncicp:def-definition></ncicp:ComplexDefinition>
self-assembly
self-assembly
npo:NPO_1971
NPO_1971
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material entity which occurs exclusively in microorganisms, plants, animals, and human beings.</ncicp:def-definition></ncicp:ComplexDefinition>
biological material entity
biological material entity
npo:NPO_1972
NPO_1972
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material entity which can be identified as an atom, ion, isotope, molecule/compound or particle.</ncicp:def-definition></ncicp:ComplexDefinition>
chemical entity
chemical entity
npo:NPO_1973
NPO_1973
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical entity which can be identified based on its physical state, chemical composition or molecular structure.</ncicp:def-definition></ncicp:ComplexDefinition>
chemical substance
chemical substance
npo:NPO_1974
NPO_1974
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical substance which as a constant, defined composition and cannot be separated into simpler substances by physical methods.</ncicp:def-definition><ncicp:attr>http://www.teacherbridge.org/public/bhs/teachers/Dana/Matter.html</ncicp:attr></ncicp:ComplexDefinition>
pure substance
pure substance
npo:NPO_1975
NPO_1975
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A biological material entity which is fluid-like.</ncicp:def-definition></ncicp:ComplexDefinition>
biological fluid
biological fluid
npo:NPO_1976
NPO_1976
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A biological material entity which is a small molecule or a macromolecule.</ncicp:def-definition></ncicp:ComplexDefinition>
biological molecule
biological molecule
npo:NPO_1977
NPO_1977
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A compound or molecule which is identified based on its application.</ncicp:def-definition></ncicp:ComplexDefinition>
compound by application
compound by application
npo:NPO_1978
NPO_1978
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A compound or molecule which is identified based on its chemical composition.</ncicp:def-definition></ncicp:ComplexDefinition>
compound by chemical composition
compound by chemical composition
npo:NPO_1979
NPO_1979
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A compound or molecule which has specific properties that makes it useful for imaging applications.</ncicp:def-definition></ncicp:ComplexDefinition>
compound for imaging
compound for imaging
npo:NPO_198
NPO_198
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 4.</ncicp:def-definition></ncicp:ComplexDefinition>
beryllium
beryllium
npo:NPO_1980
NPO_1980
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A compound or molecule which plays a role in a reaction or material synthesis.</ncicp:def-definition></ncicp:ComplexDefinition>
compound for material synthesis
compound for material synthesis
npo:NPO_1981
NPO_1981
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A compound or molecule which is used for targeting other molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
compound for targeting
compound for targeting
npo:NPO_1982
NPO_1982
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A compound or molecule which is used for therapeutic applications.</ncicp:def-definition></ncicp:ComplexDefinition>
compound for therapy
compound for therapy
npo:NPO_1983
NPO_1983
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>journal article [to be defined]</ncicp:def-definition></ncicp:ComplexDefinition>
journal article
journal article
npo:NPO_1984
NPO_1984
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>datatye [definition to be added]</ncicp:def-definition></ncicp:ComplexDefinition>
datatype
datatype
npo:NPO_1985
NPO_1985
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>string datatype</ncicp:def-definition></ncicp:ComplexDefinition>
string
string
npo:NPO_1986
NPO_1986
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>integer datatype</ncicp:def-definition></ncicp:ComplexDefinition>
integer
integer
npo:NPO_1987
NPO_1987
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>floating point datatype</ncicp:def-definition></ncicp:ComplexDefinition>
floating point
floating point
npo:NPO_1989
NPO_1989
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A collection of processes that leads the way for blood coagulation to take place.</ncicp:def-definition></ncicp:ComplexDefinition>
blood coagulation pathway
blood coagulation pathway
npo:NPO_199
NPO_199
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical substance which has atleast one external dimension or internal structure or surface structure in the nanoscale size range.</ncicp:def-definition><ncicp:attr>ISO/TS 80004-1</ncicp:attr></ncicp:ComplexDefinition>
nanomaterial
nanomaterial
npo:NPO_1990
NPO_1990
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>[definition to be entered]</ncicp:def-definition></ncicp:ComplexDefinition>
intrinsic pathway of blood coagulation
intrinsic pathway of blood coagulation
npo:NPO_1991
NPO_1991
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>[definition to be entered]</ncicp:def-definition></ncicp:ComplexDefinition>
extrinsic pathway of blood coagulation
extrinsic pathway of blood coagulation
npo:NPO_1992
NPO_1992
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>[definition to be entered]</ncicp:def-definition></ncicp:ComplexDefinition>
final common pathway of blood coagulation
final common pathway of blood coagulation
npo:NPO_1993
NPO_1993
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Time needed for blood coagulation to occur.</ncicp:def-definition></ncicp:ComplexDefinition>
blood coagulation time
blood coagulation time
npo:NPO_1994
NPO_1994
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>[definition to be entered]</ncicp:def-definition></ncicp:ComplexDefinition>
activated partial thromboplastin time
APTT
activated partial thromboplastin time
npo:NPO_1995
NPO_1995
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>[definition to be entered]</ncicp:def-definition></ncicp:ComplexDefinition>
prothrombin time
PT
prothrombin time
npo:NPO_1996
NPO_1996
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>[definition to be entered]</ncicp:def-definition></ncicp:ComplexDefinition>
thrombin time
TT
thrombin time
npo:NPO_1997
NPO_1997
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is used to measure the time required for a sample of fluid (blood) to coagulate.</ncicp:def-definition></ncicp:ComplexDefinition>
coagulometer
coagulometer
npo:NPO_1998
NPO_1998
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A biological material entity that is analyzed in a bioassay.</ncicp:def-definition></ncicp:ComplexDefinition>
biological specimen
biospecimen
biological specimen
npo:NPO_1999
NPO_1999
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is a machine that uses centrifugal force to separate substances of different densities or to remove moisture.</ncicp:def-definition><ncicp:attr>http://www.merriam-webster.com (last accessed: November 6, 2011)</ncicp:attr></ncicp:ComplexDefinition>
centrifuge
centrifuge
npo:NPO_200
NPO_200
<ncicp:ComplexDefinition><ncicp:def-definition>A disposition, inhering in any material entity, whose structure or function can be altered by changes in pH of the medium containing it.</ncicp:def-definition></ncicp:ComplexDefinition>
pH-sensitive
sensitive to pH Change
pH-sensitive
npo:NPO_2000
NPO_2000
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A technique used for incubating mixtures in an assay.</ncicp:def-definition></ncicp:ComplexDefinition>
incubation
incubation
npo:NPO_203
NPO_203
<ncicp:ComplexDefinition><ncicp:def-definition>Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.</ncicp:def-definition></ncicp:ComplexDefinition>
DNA topoisomerase type I activity
DNA topoisomerase type I activity
87
npo:NPO_205
NPO_205
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 87.</ncicp:def-definition></ncicp:ComplexDefinition>
francium atom
francium atom
npo:NPO_206
NPO_206
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular role which inheres specifically in a a chemical component of a nanoparticle formulation with respect to its use in the formulation of nanoparticles.</ncicp:def-definition></ncicp:ComplexDefinition>
component role in nanoparticle
component role in nanoparticle
npo:NPO_207
NPO_207
<ncicp:ComplexDefinition><ncicp:def-definition>The hydrophobic space within the lipid bilayer.</ncicp:def-definition></ncicp:ComplexDefinition>
hydrophobic core of lipid bilayer
hydrophobic core of lipid bilayer
npo:NPO_208
NPO_208
<ncicp:ComplexDefinition><ncicp:def-definition>An aryl halide group containing an aromatic benzene ring attached to one or more fluorine atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
fluorobenzene group
fluorobenzene group
55
npo:NPO_209
NPO_209
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 55.</ncicp:def-definition></ncicp:ComplexDefinition>
caesium atom
caesium atom
npo:NPO_210
NPO_210
<ncicp:ComplexDefinition><ncicp:def-definition>A series element which is an alkali earth metal or alkali metal or inner transition element or transition element or other metal.</ncicp:def-definition></ncicp:ComplexDefinition>
metal
metal
npo:NPO_211
NPO_211
<ncicp:ComplexDefinition><ncicp:def-definition>A linkage in which two molecular entities or parts thereof are joined to form a chemically conjugated molecular entity.</ncicp:def-definition></ncicp:ComplexDefinition>
attachment
chemical conjugation
attachment
npo:NPO_212
NPO_212
<ncicp:ComplexDefinition><ncicp:def-definition>A covalent linkage where a sulfonamide group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
sulfonamide linkage
sulfonamide linkage
28
npo:NPO_213
NPO_213
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 28.</ncicp:def-definition></ncicp:ComplexDefinition>
nickel atom
nickel atom
npo:NPO_214
NPO_214
<ncicp:ComplexDefinition><ncicp:def-definition>An independent continuant which describes a 2-dimensional, inner/outer surface of a material entity. The material boundary separates a material entity in its identity from other surrounding material entities.</ncicp:def-definition></ncicp:ComplexDefinition>
material boundary
material surface
surface
material boundary
npo:NPO_216
NPO_216
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 80.</ncicp:def-definition></ncicp:ComplexDefinition>
mercury
mercury
npo:NPO_218
NPO_218
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which has a coating agent composed of polymer.</ncicp:def-definition></ncicp:ComplexDefinition>
polymer-coated nanoparticle
polymer-coated nanoparticle
npo:NPO_219
NPO_219
<ncicp:ComplexDefinition><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by electric field.</ncicp:def-definition></ncicp:ComplexDefinition>
stimulus of electric field
stimulus of electric field
npo:NPO_220
NPO_220
<ncicp:ComplexDefinition><ncicp:def-definition>A non-metal which is any of the following elements: carbon, nitrogen, oxygen, phosphorus, selenium, sulfur.</ncicp:def-definition></ncicp:ComplexDefinition>
other non-metal
other non-metal
npo:NPO_221
NPO_221
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which has the structure N#C-S-. The group is characteristic of a thiocyanate organic molecule wherein it is attached to an organic group via a single covalent bond.</ncicp:def-definition></ncicp:ComplexDefinition>
thiocyanate group
thiocyanate group
9
npo:NPO_222
NPO_222
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 9.</ncicp:def-definition></ncicp:ComplexDefinition>
fluorine atom
fluorine atom
npo:NPO_223
NPO_223
<ncicp:ComplexDefinition><ncicp:def-definition>A permanent dipole-dipole interaction between a hydrogen atom of -OH or -NH part of a molecule and a small, highly electronegative atom of the other polar molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
hydrogen bonding
hydrogen bonding
npo:NPO_224
NPO_224
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular structure which describes an interior layer, formed around the dendrimer core by the addition of dendrimer branches.</ncicp:def-definition></ncicp:ComplexDefinition>
dendrimer generation layer
dendrimer generation layer
41
npo:NPO_225
NPO_225
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 41.</ncicp:def-definition></ncicp:ComplexDefinition>
niobium atom
niobium atom
npo:NPO_226
NPO_226
<ncicp:ComplexDefinition><ncicp:def-definition>A nano-object which has two external dimensions in the nanoscale (between 1 and 1000 nm) range.</ncicp:def-definition></ncicp:ComplexDefinition>
two-dimensional nano-object
2-D nano-object
two-dimensional nano-object
npo:NPO_227
NPO_227
<ncicp:ComplexDefinition><ncicp:def-definition>A targeting agent, which is a ligand or small molecule that binds to larger molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
targeting ligand
targeting ligand
npo:NPO_228
NPO_228
<ncicp:ComplexDefinition><ncicp:def-definition>An inorganic compound or molecule which is composed of cadmium and selenium.</ncicp:def-definition></ncicp:ComplexDefinition>
cadmium selenide
CdSe
cadmium selenide
npo:NPO_229
NPO_229
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which has the structure -E(=O)-NH2 or -E(=O)-NH- or -E(=O)-N(-)-, where E could denote one of the following atoms: carbon (C), sulfur (S) or phosphorus (P). The group is characteristic of an amide compound wherein it is attached to organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
amide group
amide group
npo:NPO_231
NPO_231
<ncicp:ComplexDefinition><ncicp:def-definition>A covalent linkage where an isothiourea group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
isothiourea linkage
isothiourea linkage
npo:NPO_233
NPO_233
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 5.</ncicp:def-definition></ncicp:ComplexDefinition>
boron
boron
npo:NPO_234
NPO_234
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group, the structure of which consists of a saturated cyclic ring made up of four carbon atoms and one nitrogen atom; and each of the two carbon atoms, adjacent to the nitrogen atom, are bonded to an oxygen atom via a double bond, while the nitrogen atom is bonded to one oxygen atom of the carbonate group.</ncicp:def-definition></ncicp:ComplexDefinition>
succinimidyl carbonate group
succinimidyl carbonate group
npo:NPO_235
NPO_235
<ncicp:ComplexDefinition><ncicp:def-definition>DNA crosslinking agent, which alkylates DNA.</ncicp:def-definition></ncicp:ComplexDefinition>
DNA alkylating agent
antineoplastic alkylating agent
DNA alkylating agent
npo:NPO_236
NPO_236
<ncicp:ComplexDefinition><ncicp:def-definition>A carbamate ester linkage which is formed between a primary amine and a carbonate ester, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
carbamate ester linkage between primary amine and carbonate ester
carbamate ester linkage between primary amine and carbonate ester
npo:NPO_238
NPO_238
<ncicp:ComplexDefinition><ncicp:def-definition>A covalent linkage where an amidine group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
amidine linkage
amidine linkage
npo:NPO_239
NPO_239
NCIT: C62367
<ncicp:ComplexDefinition><ncicp:def-definition>A nanodevice which has the end-directed activity/function to serve as an explosive device.</ncicp:def-definition></ncicp:ComplexDefinition>
nanobomb
An explosive device comprised of carbon nanotubes. These nanoscale devices have desirable optical and thermal properties that can be exploited for novel cancer therapeutics. The ability to manipulate these properties facilitates a controlled, localized activation and clearance mechanism of diseased or abnormal cells.
nanobomb
npo:NPO_240
NPO_240
<ncicp:ComplexDefinition><ncicp:def-definition>A covalent linkage where an isourea group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
isourea linkage
isourea linkage
npo:NPO_241
NPO_241
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spheroidal shape, which is generated by half-revolution of an ellipse around its minor axis.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
oblate spheroidal shape
oblate spheroidal shape
npo:NPO_242
NPO_242
<ncicp:ComplexDefinition><ncicp:def-definition>An aminoacid which can become ionized.</ncicp:def-definition></ncicp:ComplexDefinition>
ionizable aminoacid
ionizable aminoacid
npo:NPO_243
NPO_243
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 66.</ncicp:def-definition></ncicp:ComplexDefinition>
dysprosium
dysprosium
npo:NPO_244
NPO_244
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 86.</ncicp:def-definition></ncicp:ComplexDefinition>
radon
radon
npo:NPO_245
NPO_245
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Outer surface of a liposome vesicle, formed by the polar head groups of lipid molecules that compose the lipid bilayer.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
outer hydrophilic surface of liposome
outer hydrophilic surface of liposome
10
npo:NPO_246
NPO_246
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 10.</ncicp:def-definition></ncicp:ComplexDefinition>
neon atom
neon atom
npo:NPO_247
NPO_247
<ncicp:ComplexDefinition><ncicp:def-definition>A covalent linkage where an imide group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
imide linkage
imide linkage
61
npo:NPO_248
NPO_248
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 61.</ncicp:def-definition></ncicp:ComplexDefinition>
promethium atom
promethium atom
npo:NPO_249
NPO_249
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 12.</ncicp:def-definition></ncicp:ComplexDefinition>
magnesium
magnesium
npo:NPO_251
NPO_251
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 20.</ncicp:def-definition></ncicp:ComplexDefinition>
calcium
calcium
npo:NPO_252
NPO_252
<ncicp:ComplexDefinition><ncicp:def-definition>An organic compound of biological origin, which contains hydrocarbons and it is insoluble in water but soluble in non-polar solvents.</ncicp:def-definition></ncicp:ComplexDefinition>
lipid
[ChEBI definition]: A loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids.
[NCI_Thesaurus definition]: A class of hydrocarbon-containing organic compounds. Lipids are insoluble in water but soluble in nonpolar solvents and play important roles in living organisms: these roles include functioning as energy storage molecules, serving as structural components of cell membranes, and constituting important signaling molecules. Lipids can be subdivided into 2 groups: fatty acids and glycerides.
lipid
npo:NPO_253
NPO_253
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 91.</ncicp:def-definition></ncicp:ComplexDefinition>
protactinium
protactinium
npo:NPO_255
NPO_255
<ncicp:ComplexDefinition><ncicp:def-definition>A series element which is not a metal.</ncicp:def-definition></ncicp:ComplexDefinition>
non-metal
non-metal
npo:NPO_256
NPO_256
NCIT: C1748
<ncicp:ComplexDefinition><ncicp:def-definition>Enzyme inhibitor that inhibits the enzymatic activity of topoisomerases.</ncicp:def-definition></ncicp:ComplexDefinition>
topoisomerase inhibitor
topoisomerase inhibitor
npo:NPO_257
NPO_257
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 9.</ncicp:def-definition></ncicp:ComplexDefinition>
fluorine
fluorine
npo:NPO_260
NPO_260
<ncicp:ComplexDefinition><ncicp:def-definition>The aqueous space between lipid bilayers (e.g, in a multilamellar vesicle).</ncicp:def-definition></ncicp:ComplexDefinition>
hydrophilic space between lipid bilayers
hydrophilic space between lipid bilayers
npo:NPO_261
NPO_261
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which is basically composed of chitosan</ncicp:def-definition></ncicp:ComplexDefinition>
chitosan nanoparticle
chitosan nanoparticle
npo:NPO_262
NPO_262
<ncicp:ComplexDefinition><ncicp:def-definition>Magnetic property exhibited in materials where the magnetic moments of adjacent atoms align in opposite directions, and this quality exists only below the Neel temperature.</ncicp:def-definition></ncicp:ComplexDefinition>
antiferromagnetic
(definition source): http://dictionary.reference.com/browse/antiferromagnetic
antiferromagnetic
npo:NPO_263
NPO_263
<ncicp:ComplexDefinition><ncicp:def-definition>A brittle transparent solid substance with irregular atomic structure.</ncicp:def-definition></ncicp:ComplexDefinition>
glass
glass
npo:NPO_264
NPO_264
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which has the structure -C(=O)-N(-)-N(-)-. The group is characteristic of a carbohydrazide compound.</ncicp:def-definition></ncicp:ComplexDefinition>
carbohydrazide group
carbohydrazide group
npo:NPO_266
NPO_266
<ncicp:ComplexDefinition><ncicp:def-definition>An element of Group 13 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
Group 13 Element
boron group element
Group 13 Element
npo:NPO_267
NPO_267
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 60.</ncicp:def-definition></ncicp:ComplexDefinition>
neodymium
neodymium
npo:NPO_268
NPO_268
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which has the structure -O-. The group is characteristic of an ether in which the oxygen atom is attached to two carbon atoms via single covalent bonds.</ncicp:def-definition></ncicp:ComplexDefinition>
ether group
ether group
npo:NPO_270
NPO_270
<ncicp:ComplexDefinition><ncicp:def-definition>A three-dimensional nanoparticle which is composed of a spherical core surrounded by a shell of a few nanometer in thickness. If the shell is made of metal particles, then it is called a metallic nanoshell (e.g. Gold nanoshell).</ncicp:def-definition></ncicp:ComplexDefinition>
nanoshell
nanoshell
npo:NPO_271
NPO_271
<ncicp:ComplexDefinition><ncicp:def-definition>An element of Group 6 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
Group 6 Element
chromium group element
Group 6 Element
npo:NPO_272
NPO_272
<ncicp:ComplexDefinition><ncicp:def-definition>A nano-object which has all three external dimensions in the nanoscale (between 1 and 1000 nm) range.</ncicp:def-definition></ncicp:ComplexDefinition>
three-dimensional nano-object
3-D nano-object
three-dimensional nano-object
npo:NPO_273
NPO_273
<ncicp:ComplexDefinition><ncicp:def-definition>An oxide of iron.</ncicp:def-definition></ncicp:ComplexDefinition>
iron oxide
iron oxide
npo:NPO_274
NPO_274
<ncicp:ComplexDefinition><ncicp:def-definition>Quality which exactly or approximately describes the external form or outline of something as distinct from its substance.</ncicp:def-definition></ncicp:ComplexDefinition>
shape
The spatial arrangement of something as distinct from its substance. [source: NCI, WordNet]
shape
npo:NPO_275
NPO_275
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 55.</ncicp:def-definition></ncicp:ComplexDefinition>
caesium
caesium
npo:NPO_276
NPO_276
<ncicp:ComplexDefinition><ncicp:def-definition>A quality inhering in a chemical substance due to the presence of a cyclically conjugated molecular entity , with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure.</ncicp:def-definition></ncicp:ComplexDefinition>
aromatic
Definition of aromatic is based on that of an aromatic compound (CHEBI:33655)
[definition source]: ChEBI
aromatic
80
npo:NPO_277
NPO_277
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 80.</ncicp:def-definition></ncicp:ComplexDefinition>
mercury atom
mercury atom
npo:NPO_278
NPO_278
<ncicp:ComplexDefinition><ncicp:def-definition>A covalent linkage where a secondary amine group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
secondary amine linkage
secondary amine linkage
npo:NPO_279
NPO_279
<ncicp:ComplexDefinition><ncicp:def-definition>The core part of a dendrimer, which is formed by the core initiator group [npo:NPO_803].</ncicp:def-definition></ncicp:ComplexDefinition>
dendrimer core
dendrimer core
npo:NPO_280
NPO_280
<ncicp:ComplexDefinition><ncicp:def-definition>An element of Group 14 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
Group 14 Element
carbon group element
Group 14 Element
npo:NPO_281
NPO_281
<ncicp:ComplexDefinition><ncicp:def-definition>Role of a molecular entity, which brings about an end therapeutic result in cancer therapy.</ncicp:def-definition></ncicp:ComplexDefinition>
anticancer drug role
anticancer drug role
npo:NPO_282
NPO_282
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 105.</ncicp:def-definition></ncicp:ComplexDefinition>
dubnium
dubnium
npo:NPO_283
NPO_283
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical substance which is composed of two or more substances (with variable composition) that are not chemically combined with each other and are capable of being separated hy physical means.</ncicp:def-definition></ncicp:ComplexDefinition>
mixture
mixture
npo:NPO_284
NPO_284
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which has two external dimensions in the nanoscale size range.</ncicp:def-definition></ncicp:ComplexDefinition>
two-dimensional nanoparticle
2-D nanoparticle
two-dimensional nanoparticle
npo:NPO_286
NPO_286
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An ellipsoidal shape inhering in 3-dimensional object, where every point on the surface is equidistant from the center of the object.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
spherical shape
spherical
spherical shape
npo:NPO_287
NPO_287
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 31.</ncicp:def-definition></ncicp:ComplexDefinition>
gallium
gallium
npo:NPO_288
NPO_288
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 73.</ncicp:def-definition></ncicp:ComplexDefinition>
tantalum
tantalum
npo:NPO_290
NPO_290
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A substance or compound, which is used to produce a chemical reaction, to detect, measure, or produce other substances; or to convert one substance into another by chemical reaction.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
reagent
reagent
npo:NPO_291
NPO_291
<ncicp:ComplexDefinition><ncicp:def-definition>A hydrazone linkage which is formed between a carbohydrazide and an aldehyde, through covalent interactions between atoms of respective functional groups..</ncicp:def-definition></ncicp:ComplexDefinition>
hydrazone linkage between carbohydrazide and aldehyde
hydrazone linkage between carbohydrazide and aldehyde
npo:NPO_292
NPO_292
obo:OBI_0000086
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Role played by a substance or compound used to produce a chemical reaction to detect, measure, or produce other substances.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
reagent role
reagent role
npo:NPO_294
NPO_294
<ncicp:ComplexDefinition><ncicp:def-definition>Drug that is directed against a tumor cell to inhibit a protein activity related to the synthesis of DNA.</ncicp:def-definition></ncicp:ComplexDefinition>
drug that affects protein activity related to DNA synthesis
drug that affects protein activity related to DNA synthesis
npo:NPO_295
NPO_295
<ncicp:ComplexDefinition><ncicp:def-definition>A sulfonamide linkage which is formed between a primary amine and a suflonyl chloride derivative, through the covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
sulfonamide linkage between primary amine and sulfonyl chloride derivative
sulfonamide linkage between primary amine and sulfonyl chloride derivative
npo:NPO_296
NPO_296
<ncicp:ComplexDefinition><ncicp:def-definition>A biological process or mechanism by which extracellular materials are taken up by a cell.</ncicp:def-definition></ncicp:ComplexDefinition>
cellular uptake of extracellular material
cellular uptake of extracellular material
30
npo:NPO_298
NPO_298
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 30.</ncicp:def-definition></ncicp:ComplexDefinition>
zinc atom
zinc atom
19
npo:NPO_300
NPO_300
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 19.</ncicp:def-definition></ncicp:ComplexDefinition>
potassium atom
potassium atom
npo:NPO_301
NPO_301
<ncicp:ComplexDefinition><ncicp:def-definition>A double-walled nanotube which consists of two graphite layers or sheets of hexagonal arrays of carbon, rolled into two concentric seamless cylinders with a diameter close to 1 nanometer.</ncicp:def-definition></ncicp:ComplexDefinition>
double-walled carbon nanotube
double-walled carbon nanotube
93
npo:NPO_304
NPO_304
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 93.</ncicp:def-definition></ncicp:ComplexDefinition>
neptunium atom
neptunium atom
17
npo:NPO_305
NPO_305
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 17.</ncicp:def-definition></ncicp:ComplexDefinition>
chlorine atom
chlorine atom
npo:NPO_306
NPO_306
<ncicp:ComplexDefinition><ncicp:def-definition>An inorganic compound or molecule which is composed of zinc and sulfur.</ncicp:def-definition></ncicp:ComplexDefinition>
zinc sulfide
zinc sulfide
npo:NPO_307
NPO_307
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A cylindrical shape inhering in 3-dimensional object with height smaller than the cross-sectional diameter.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
disc-shaped
disclike
disk-shaped
disklike
disc-shaped
npo:NPO_308
NPO_308
<ncicp:ComplexDefinition><ncicp:def-definition>Drug that is directed to affect the synthesis and function of endothelial growth factor.</ncicp:def-definition></ncicp:ComplexDefinition>
anticancer drug directed against endothelial growth factor
anticancer drug directed against endothelial growth factor
npo:NPO_310
NPO_310
<ncicp:ComplexDefinition><ncicp:def-definition>An element that has the same number of electron shells as other elements of a horizontal row in the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
period element
period element
npo:NPO_311
NPO_311
<ncicp:ComplexDefinition><ncicp:def-definition>An amide linkage which is formed between a primary amine and an acid anhydride.</ncicp:def-definition></ncicp:ComplexDefinition>
amide linkage between primary amine and acid anhydride
amide linkage between primary amine and acid anhydride
npo:NPO_312
NPO_312
NCIT: C1909
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A compound or molecule which has the intended function to furnish pharmacological activity or other direct effect in the cure, mitigation, treatment or prevention of cancer.</ncicp:def-definition></ncicp:ComplexDefinition>
anticancer drug
chemotherapeutic agent
drug
therapeutic agent
anticancer drug
npo:NPO_313
NPO_313
<ncicp:ComplexDefinition><ncicp:def-definition>An attractive type of chemical interaction that holds atoms together in a molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
intramolecular interaction
intramolecular interaction
npo:NPO_314
NPO_314
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 13.</ncicp:def-definition></ncicp:ComplexDefinition>
aluminium
aluminium
npo:NPO_315
NPO_315
NCIT:C25974
<ncicp:ComplexDefinition><ncicp:def-definition>An antimitotic agent, which binds to tubulin and inhibits its action.</ncicp:def-definition></ncicp:ComplexDefinition>
tubulin binding agent
tubulin binding agent
npo:NPO_317
NPO_317
<ncicp:ComplexDefinition><ncicp:def-definition>The hollow core region of a nanocapsule.</ncicp:def-definition></ncicp:ComplexDefinition>
hollow core of nanocapsule
hollow core of nanocapsule
npo:NPO_318
NPO_318
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 84.</ncicp:def-definition></ncicp:ComplexDefinition>
polonium
polonium
npo:NPO_319
NPO_319
NCIT:C19151
<ncicp:ComplexDefinition><ncicp:def-definition>Metastasis is the spread or migration of cancer cells from one part of the body (the organ in which it first appeared) to another. The secondary tumor contains cells that are like those in the original (primary) tumor. For example, breast cancer cells may spread (metastasize) to the lungs and cause the growth of a new tumor. When this happens, the disease is called metastatic breast cancer. (NCI)</ncicp:def-definition></ncicp:ComplexDefinition>
metastasis
tumor cell migration
metastasis
npo:NPO_320
NPO_320
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An ellipsoidal shape, which is generated by half-revolution of an ellipse around its major axis or minor axis.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
spheroidal shape
spheroidal shape
npo:NPO_321
NPO_321
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which has the structure -N=C=O. The group is characteristic of a isocyanate compounds wherein it is attached to an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
isocyanate group
isocyanate group
npo:NPO_322
NPO_322
<ncicp:ComplexDefinition><ncicp:def-definition>A supramolecular structure which is a membrane composed of lipid molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
lipid membrane
lipid membrane
105
npo:NPO_323
NPO_323
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 105.</ncicp:def-definition></ncicp:ComplexDefinition>
dubnium atom
dubnium atom
npo:NPO_324
NPO_324
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 25.</ncicp:def-definition></ncicp:ComplexDefinition>
manganese
manganese
npo:NPO_325
NPO_325
NCIT: C390
<ncicp:ComplexDefinition><ncicp:def-definition>A diagnostic imaging agent, which is used during an imaging procedure to allow the delineation of biological structures in their images. Contrast agents appear opaque due to the difference in absorption of X-rays or other electromagnetic waves and surrounding tissue.</ncicp:def-definition></ncicp:ComplexDefinition>
contrast agent
contrast agent
npo:NPO_326
NPO_326
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which has the structure -[N+]#N. The group is characteristic of diazonium compounds.</ncicp:def-definition></ncicp:ComplexDefinition>
diazonium group
diazonium group
npo:NPO_327
NPO_327
<ncicp:ComplexDefinition><ncicp:def-definition>Antineoplastic agent,which regulates DNA-dependent transcription.</ncicp:def-definition></ncicp:ComplexDefinition>
DNA-RNA transcription regulator
DNA-RNA transcription regulator
npo:NPO_328
NPO_328
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 10.</ncicp:def-definition></ncicp:ComplexDefinition>
neon
neon
npo:NPO_330
NPO_330
<ncicp:ComplexDefinition><ncicp:def-definition>A diazonium compound is an organic compound which is characterized by the presence of a diazonium group. It has the structure R-[N+]#N, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
diazonium compound
diazonium compound
npo:NPO_331
NPO_331
<ncicp:ComplexDefinition><ncicp:def-definition>Magnetic property exhibited by materials in presence of an external magnetic field and in these materials the magnetic moment of the atoms on different sublattices are opposed, and the opposing magnetic moments are unequal, and therefore, a spontaneous magnetization remains. This property exists below the Curie temperature.</ncicp:def-definition></ncicp:ComplexDefinition>
ferrimagnetic
ferrimagnetic
npo:NPO_332
NPO_332
<ncicp:ComplexDefinition><ncicp:def-definition>An inner transition element which is any element with atomic numbers 57 (lanthanum) to 71 (Lutetium).</ncicp:def-definition></ncicp:ComplexDefinition>
Lanthanide
Lanthanide
88
npo:NPO_333
NPO_333
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 88.</ncicp:def-definition></ncicp:ComplexDefinition>
radium atom
radium atom
npo:NPO_334
NPO_334
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 24.</ncicp:def-definition></ncicp:ComplexDefinition>
chromium
chromium
92
npo:NPO_335
NPO_335
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 92.</ncicp:def-definition></ncicp:ComplexDefinition>
uranium atom
uranium atom
npo:NPO_337
NPO_337
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which is formed and held together by non-covalent interactions of molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
supramolecular entity
supramolecular entity
npo:NPO_338
NPO_338
MESH: D008051
<ncicp:ComplexDefinition><ncicp:def-definition>A lipid membrane which is two (lipid) molecules thick.</ncicp:def-definition></ncicp:ComplexDefinition>
lipid bilayer
lipid bilayer
npo:NPO_339
NPO_339
<ncicp:ComplexDefinition><ncicp:def-definition>A halo group in which the halogen atom is a bromine atom.</ncicp:def-definition></ncicp:ComplexDefinition>
bromo group
bromo group
npo:NPO_340
NPO_340
<ncicp:ComplexDefinition><ncicp:def-definition>An imidoester compound is an organic compound which is characterized by the presence of an imidoester group. It has the structure R-C(=[NH2]+)-O-CH3, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
imidoester compound
imidoester compound
40
npo:NPO_341
NPO_341
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 40.</ncicp:def-definition></ncicp:ComplexDefinition>
zirconium atom
zirconium atom
npo:NPO_342
NPO_342
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An elliptical shape in which the two foci are coincident that it is formed by a closed curve that is the path, traced by a point moving in a plane so that its distance from a fixed point (the circle's center) is a constant.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
circular shape
circular
[definition based on source]:http://www.cycfoundation.org, http://www.thefreedictionary.com, NCI
circular shape
npo:NPO_343
NPO_343
<ncicp:ComplexDefinition><ncicp:def-definition>A dipole-dipole interaction between a polar molecule and a non-polar molecule due to attraction between permanent dipole on the polar molecule and temporary dipole on the non-polar molecule; the temporary dipole on the non-polar molecule is induced by the permanent dipole on the polar molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
dipole-induced dipole interaction
It occurs when a non-polar molecule dissolves in a polar or a dipolar solvent under the assumption that the solute dissolves because the attractive force between the solvent and solute are stronger than the intermolecular forces, holding the non-polar solute molecules together.
dipole-induced dipole interaction
npo:NPO_344
NPO_344
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which consists of an aromatic ring bonded to one or more halogen atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
aryl halide group
aryl halide group
npo:NPO_345
NPO_345
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which consists of a nitrogen atom bonded to two adjacent carbon atoms in the form of a 3-membered saturated ring structure; it has the structure C1-C-N1. And the group is characteristic of any aziridine derivative.</ncicp:def-definition></ncicp:ComplexDefinition>
aziridine group
aziridine group
37
npo:NPO_347
NPO_347
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 37.</ncicp:def-definition></ncicp:ComplexDefinition>
rubidium atom
rubidium atom
npo:NPO_348
NPO_348
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 62.</ncicp:def-definition></ncicp:ComplexDefinition>
samarium
samarium
76
npo:NPO_349
NPO_349
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 76.</ncicp:def-definition></ncicp:ComplexDefinition>
osmium atom
osmium atom
npo:NPO_350
NPO_350
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 37.</ncicp:def-definition></ncicp:ComplexDefinition>
rubidium
rubidium
npo:NPO_351
NPO_351
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A compound or molecule, in which carbon is not the principal element.</ncicp:def-definition></ncicp:ComplexDefinition>
inorganic compound or molecule
inorganic compound
inorganic molecule
inorganic compound or molecule
101
npo:NPO_353
NPO_353
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 101.</ncicp:def-definition></ncicp:ComplexDefinition>
mendelevium atom
mendelevium atom
npo:NPO_354
NPO_354
<ncicp:ComplexDefinition><ncicp:def-definition>A multi-walled nanotube which consists of multiple graphite layers or sheets of hexagonal arrays of carbon, rolled in on themselves to form concentric seamless cylinders with a diameter close to 1 nanometer.</ncicp:def-definition></ncicp:ComplexDefinition>
multi-walled carbon nanotube
MWCNT
multi-walled carbon nanotube
npo:NPO_356
NPO_356
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle response to external stimulus, which occurs in response to ultrasound.</ncicp:def-definition></ncicp:ComplexDefinition>
nanoparticle response to ultrasound
nanoparticle response to ultrasound
npo:NPO_357
NPO_357
<ncicp:ComplexDefinition><ncicp:def-definition>A group that forms the sidechain of an alpha-aminoacid.</ncicp:def-definition></ncicp:ComplexDefinition>
alpha-aminoacid sidechain
alpha-aminoacid sidechain
npo:NPO_358
NPO_358
<ncicp:ComplexDefinition><ncicp:def-definition>An element of Group 4 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
Group 4 Element
titanium group element
Group 4 Element
npo:NPO_359
NPO_359
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 97.</ncicp:def-definition></ncicp:ComplexDefinition>
berkelium
berkelium
npo:NPO_360
NPO_360
NCIT:C32345
<ncicp:ComplexDefinition><ncicp:def-definition>A suspension of particles (dispersed phase) in a liquid medium (dispersion medium or continuous phase).</ncicp:def-definition></ncicp:ComplexDefinition>
colloid
colloid
npo:NPO_363
NPO_363
<ncicp:ComplexDefinition><ncicp:def-definition>A material site which is in the core of a material entity; which is hollow or a void space, into which molecular agents like drugs, imaging agents, etc. can be placed.</ncicp:def-definition></ncicp:ComplexDefinition>
core site
core site
59
npo:NPO_366
NPO_366
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 59.</ncicp:def-definition></ncicp:ComplexDefinition>
praseodymium atom
praseodymium atom
72
npo:NPO_367
NPO_367
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 72.</ncicp:def-definition></ncicp:ComplexDefinition>
hafnium atom
hafnium atom
npo:NPO_368
NPO_368
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 107.</ncicp:def-definition></ncicp:ComplexDefinition>
bohrium
bohrium
83
npo:NPO_369
NPO_369
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 83.</ncicp:def-definition></ncicp:ComplexDefinition>
bismuth atom
bismuth atom
npo:NPO_370
NPO_370
<ncicp:ComplexDefinition><ncicp:def-definition>An aziridine derivative is an organic compound which is characterized by the presence of an aziridine group. It has the structure R-C1H-CH2-C1H, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
aziridine derivative
aziridine derivative
npo:NPO_371
NPO_371
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 15.</ncicp:def-definition></ncicp:ComplexDefinition>
phosphorus
phosphorus
npo:NPO_372
NPO_372
<ncicp:ComplexDefinition><ncicp:def-definition>An isothiourea linkage which is formed between a primary amine and an isothiocyanate, through covalent interactions between atoms of respective functional groups..</ncicp:def-definition></ncicp:ComplexDefinition>
linkage between primary amine and isothiocyanate
linkage between primary amine and isothiocyanate
38
npo:NPO_374
NPO_374
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 38.</ncicp:def-definition></ncicp:ComplexDefinition>
strontium atom
strontium atom
npo:NPO_375
NPO_375
<ncicp:ComplexDefinition><ncicp:def-definition>An element of Group 15 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
Group 15 Element
pnictogen
Group 15 Element
npo:NPO_376
NPO_376
<ncicp:ComplexDefinition><ncicp:def-definition>An isourea linkage which is formed between a primary amine and an isocyanate, through the covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
isourea linkage between primary amine and isocyanate
isourea linkage between primary amine and isocyanate
50
npo:NPO_377
NPO_377
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 50.</ncicp:def-definition></ncicp:ComplexDefinition>
tin atom
tin atom
45
npo:NPO_378
NPO_378
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 45.</ncicp:def-definition></ncicp:ComplexDefinition>
rhodium atom
rhodium atom
npo:NPO_379
NPO_379
<ncicp:ComplexDefinition><ncicp:def-definition>A contrast agent, which has optical properties, and provides contrast in images captured using optical imaging techniques.</ncicp:def-definition></ncicp:ComplexDefinition>
optical imaging contrast agent
optical imaging contrast agent
npo:NPO_380
NPO_380
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 64.</ncicp:def-definition></ncicp:ComplexDefinition>
gadolinium
gadolinium
44
npo:NPO_382
NPO_382
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 44.</ncicp:def-definition></ncicp:ComplexDefinition>
ruthenium atom
ruthenium atom
npo:NPO_383
NPO_383
NCIT: C62376
<ncicp:ComplexDefinition><ncicp:def-definition>A two-dimensional nano-object which has a wire-like structure made of materials that exhibit unique electrical and optical properties.</ncicp:def-definition></ncicp:ComplexDefinition>
nanowire
nanowire
npo:NPO_385
NPO_385
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 67.</ncicp:def-definition></ncicp:ComplexDefinition>
holmium
holmium
npo:NPO_388
NPO_388
<ncicp:ComplexDefinition><ncicp:def-definition>A non-covalent interaction which is a repulsive interaction between hydrophobic molecule or hydrophobic part of an amphiphilic molecule and water molecules in aqueous solutions. It results from energetically favorable interactions between hydrophilic molecules or parts there of and water molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
hydrophobic interaction
hydrophobic interaction
npo:NPO_389
NPO_389
<ncicp:ComplexDefinition><ncicp:def-definition>An arylamine linkage which is formed between a primary amine and a fluorobenzene derivative, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
arylamine linkage between primary amine and fluorobenzene derivative
arylamine linkage between primary amine and fluorobenzene derivative
npo:NPO_390
NPO_390
NCIT: C1557
<ncicp:ComplexDefinition><ncicp:def-definition>Antineoplastic antimetabolite which affects the metabolism and utilization of pyrimidines.</ncicp:def-definition></ncicp:ComplexDefinition>
pyrimidine antagonist
pyrimidine antagonist
npo:NPO_391
NPO_391
<ncicp:ComplexDefinition><ncicp:def-definition>An amidine group which has the structure -C(=N-)-NH2. It is characteristic of a carboxamidine compound.</ncicp:def-definition></ncicp:ComplexDefinition>
carboxamidine group
carboxamidine group
npo:NPO_393
NPO_393
NCIT: C62369
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle formulation which exists as an emulsion and contains nanoparticles as the dispersed phase.</ncicp:def-definition></ncicp:ComplexDefinition>
nanoemulsion
nanoparticle emulsion
nanoemulsion
npo:NPO_394
NPO_394
<ncicp:ComplexDefinition><ncicp:def-definition>An amide group which has the structure -C(=O)-N(-[*])-C(=O)-. The group is characteristic of an imide compound.</ncicp:def-definition></ncicp:ComplexDefinition>
imide group
imide group
npo:NPO_395
NPO_395
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which is loaded with a drug.</ncicp:def-definition></ncicp:ComplexDefinition>
drug-loaded nanoparticle
drug-loaded nanoparticle
103
npo:NPO_396
NPO_396
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 103.</ncicp:def-definition></ncicp:ComplexDefinition>
lawrencium atom
lawrencium atom
npo:NPO_398
NPO_398
<ncicp:ComplexDefinition><ncicp:def-definition>A nanotube which consists of two layers or sheets of hexagonal arrays of an element or molecule, rolled into two concentric seamless cylinders with a diameter close to 1 nanometer.</ncicp:def-definition></ncicp:ComplexDefinition>
double-walled nanotube
double-walled nanotube
3
npo:NPO_400
NPO_400
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 3.</ncicp:def-definition></ncicp:ComplexDefinition>
lithium atom
lithium atom
npo:NPO_401
NPO_401
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which is basically composed of gold element.</ncicp:def-definition></ncicp:ComplexDefinition>
gold nanoparticle
Au nanoparticle
gold nanoparticle
npo:NPO_402
NPO_402
<ncicp:ComplexDefinition><ncicp:def-definition>A cyanate is an organic compound which is characterized by the presence of a cyanate group. It has the structure R-O-C#N, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
cyanate
cyanate
5
npo:NPO_403
NPO_403
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 5.</ncicp:def-definition></ncicp:ComplexDefinition>
boron atom
boron atom
39
npo:NPO_404
NPO_404
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 39.</ncicp:def-definition></ncicp:ComplexDefinition>
yttrium atom
yttrium atom
npo:NPO_405
NPO_405
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which has the structure R-C(=O)-[N+]#N, where R denotes any organic group. The group is characteristic of acyl azide compounds.</ncicp:def-definition></ncicp:ComplexDefinition>
acyl azide group
The structure of an acyl azide is R-C(=O)-[N+]#N, in which an acyl group is bound to a diazonium group.
acyl azide group
npo:NPO_407
NPO_407
<ncicp:ComplexDefinition><ncicp:def-definition>The central part of a nanocell.</ncicp:def-definition></ncicp:ComplexDefinition>
nuclear core of nanocell
nuclear core of nanocell
npo:NPO_408
NPO_408
<ncicp:ComplexDefinition><ncicp:def-definition>An element of the periodic table for which, in the atomic ground state, the highest-energy electrons occupy f-orbitals.</ncicp:def-definition></ncicp:ComplexDefinition>
f-block element
f-block element
npo:NPO_409
NPO_409
NCIT: C2167
<ncicp:ComplexDefinition><ncicp:def-definition>Tyrosine kinase inhibitor, which inhibits Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase, involved with signal transduction pathways, and may be useful in treating tumors that over express EGFR. [source:NCI_Thesaurus]</ncicp:def-definition></ncicp:ComplexDefinition>
epidermal growth factor receptor tyrosine kinase inhibitor
EGFR-TK inhibitor
epidermal growth factor receptor tyrosine kinase inhibitor
npo:NPO_410
NPO_410
<ncicp:ComplexDefinition><ncicp:def-definition>A quality that inheres in a molecule or chemical bond due to the presence of dipole moments.</ncicp:def-definition></ncicp:ComplexDefinition>
polar
polar
npo:NPO_411
NPO_411
<ncicp:ComplexDefinition><ncicp:def-definition>A nano-object which has only one external dimension in the nanoscale (between 1 and 1000 nm) range.</ncicp:def-definition></ncicp:ComplexDefinition>
one-dimensional nano-object
1-D nano-object
one-dimensional nano-object
npo:NPO_412
NPO_412
<ncicp:ComplexDefinition><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by light.</ncicp:def-definition></ncicp:ComplexDefinition>
stimulus of light
stimulus of electromagnetic radiation
stimulus of light
npo:NPO_413
NPO_413
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 56.</ncicp:def-definition></ncicp:ComplexDefinition>
barium
barium
npo:NPO_414
NPO_414
<ncicp:ComplexDefinition><ncicp:def-definition>A thioether linkage which is formed between a thiol and an acryloyl compound, through the covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
thioether linkage between thiol and acryloyl compound
thioether linkage between thiol and acryloyl compound
npo:NPO_416
NPO_416
<ncicp:ComplexDefinition><ncicp:def-definition>A hydrazone linkage which is formed between a carbohydrazide and a ketone, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
hydrazone linkage between carbohydrazide and ketone
hydrazone linkage between carbohydrazide and ketone
1
npo:NPO_418
NPO_418
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 1.</ncicp:def-definition></ncicp:ComplexDefinition>
hydrogen atom
hydrogen atom
npo:NPO_419
NPO_419
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 29.</ncicp:def-definition></ncicp:ComplexDefinition>
copper
copper
npo:NPO_420
NPO_420
<ncicp:ComplexDefinition><ncicp:def-definition>A metal which is either an actinide or a lanthanide.</ncicp:def-definition></ncicp:ComplexDefinition>
inner transition element
inner transition element
npo:NPO_421
NPO_421
<ncicp:ComplexDefinition><ncicp:def-definition>A realizable entity that describes the ability of an atom in a molecule to draw bonding electrons to itself.</ncicp:def-definition></ncicp:ComplexDefinition>
electronegativity
[definition source]: http://hyperphysics.phy-astr.gsu.edu/Hbase/hframe.html
electronegativity
npo:NPO_424
NPO_424
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 51.</ncicp:def-definition></ncicp:ComplexDefinition>
lead
lead
npo:NPO_425
NPO_425
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 75.</ncicp:def-definition></ncicp:ComplexDefinition>
rhenium
rhenium
npo:NPO_426
NPO_426
<ncicp:ComplexDefinition><ncicp:def-definition>A halo group in which the halogen atom is a iodine atom.</ncicp:def-definition></ncicp:ComplexDefinition>
iodo group
iodo group
npo:NPO_428
NPO_428
<ncicp:ComplexDefinition><ncicp:def-definition>A qualitative measure of "ionizability" which indicates that the bearer can be ionized to gain negative or positive charges.</ncicp:def-definition></ncicp:ComplexDefinition>
ionizable
ionizable
npo:NPO_429
NPO_429
<ncicp:ComplexDefinition><ncicp:def-definition>A carbonate ester is an organic compound which is a diester derivative of carbonate and it is characterized by the presence of a "carbonate ester group." It has the structure R-O-C(=O)-O-R', where R, R' denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
carbonate ester
carbonate compound
carbonate ester
npo:NPO_430
NPO_430
<ncicp:ComplexDefinition><ncicp:def-definition>A covalent linkage where a hydrazone group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
hydrazone linkage
hydrazone linkage
npo:NPO_431
NPO_431
<ncicp:ComplexDefinition><ncicp:def-definition>An imide group derived from maleimide by the removal of a hydrogen atom that was attached to nitrogen atom of the parent maleimide. The group is characteristic of any maleimide derivative.</ncicp:def-definition></ncicp:ComplexDefinition>
maleimide group
maleimide group
npo:NPO_432
NPO_432
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 49.</ncicp:def-definition></ncicp:ComplexDefinition>
indium
indium
npo:NPO_433
NPO_433
<ncicp:ComplexDefinition><ncicp:def-definition>A liposome vesicle that has more than one lipid bilayer, and the bilayers are separated by hydrophilic spaces.</ncicp:def-definition></ncicp:ComplexDefinition>
multilamellar vesicle
multilamellar vesicle
npo:NPO_434
NPO_434
NCIT: C870
<ncicp:ComplexDefinition><ncicp:def-definition>A synthetic derivative of glutamic acid (alpha-phthalimido-glutarimide) with teratogenic, immunomodulatory, anti-inflammatory and anti-angiogenic properties. Thalidomide acts primarily by inhibiting both the production of tumor necrosis factor alpha (TNF-alpha) in stimulated peripheral monocytes and the activities of interleukins and interferons. This agent also inhibits polymorphonuclear chemotaxis and monocyte phagocytosis. In addition, thalidomide inhibits pro-angiogenic factors such as vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), thereby inhibiting angiogenesis.</ncicp:def-definition></ncicp:ComplexDefinition>
thalidomide
2-(2,6-dioxopiperidin-3-yl) isoindoline-1,3-dione [source: IUPAC]
Anticancer Drug Directed Against Endothelial Growth Factor Receptor
thalidomide
npo:NPO_435
NPO_435
<ncicp:ComplexDefinition><ncicp:def-definition>An enzyme inhibitor, which inhibits thymidylate synthase, an enzyme that catalyses the de novo synthesis of deoxythymidylate and acts as a key rate-limiting enzyme of DNA synthesis.</ncicp:def-definition></ncicp:ComplexDefinition>
thymidylate synthase inhibitor
thymidylate synthetase inhibitor
thymidylate synthase inhibitor
npo:NPO_437
NPO_437
<ncicp:ComplexDefinition><ncicp:def-definition>Drug that is directed against a tumor cell to modify the expression of specific genes.</ncicp:def-definition></ncicp:ComplexDefinition>
Anticancer drug that modifies expression of specific genes
anticancer drug that modifies expression of specific genes
2
npo:NPO_438
NPO_438
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 2.</ncicp:def-definition></ncicp:ComplexDefinition>
helium atom
helium atom
npo:NPO_439
NPO_439
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 14.</ncicp:def-definition></ncicp:ComplexDefinition>
silicon
silicon
npo:NPO_440
NPO_440
NCIT:C2120
<ncicp:ComplexDefinition><ncicp:def-definition>An anti-adhesion agent, which inhibits lectin, a protein that binds carbohydrate on cell surfaces and causes cell agglutination.</ncicp:def-definition></ncicp:ComplexDefinition>
lectin inhibitor
lectin inhibitor
npo:NPO_441
NPO_441
<ncicp:ComplexDefinition><ncicp:def-definition>An aryl halide derived from fluorobenzene.</ncicp:def-definition></ncicp:ComplexDefinition>
fluorobenzene derivative
fluorobenzene derivative
npo:NPO_442
NPO_442
MESH: D004791
NCIT: C471
<ncicp:ComplexDefinition><ncicp:def-definition>Antineoplastic agent, which binds to an enzyme and decreases or blocks the enzyme's activity by hindering the normal substrate-enzyme combination and the catalytic reaction.</ncicp:def-definition></ncicp:ComplexDefinition>
enzyme inhibitor drug
enzyme antagonist
enzyme inhibitor
Only those enzyme inhibitors that are used as cancer drugs should be included under this class.
enzyme inhibitor drug
36
npo:NPO_443
NPO_443
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 36.</ncicp:def-definition></ncicp:ComplexDefinition>
krypton atom
krypton atom
npo:NPO_446
NPO_446
<ncicp:ComplexDefinition><ncicp:def-definition>An element of Group 17 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
Group 17 Element
halogen
Group 17 Element
npo:NPO_447
NPO_447
<ncicp:ComplexDefinition><ncicp:def-definition>A two-dimensional nano-object which is a capillary tube with diameter in the nanometer range. Nanopipettes made from standard quartz capillary tubes are known to detect single molecules which are labeled with gold nanoparticles.</ncicp:def-definition></ncicp:ComplexDefinition>
nanopipette
nanopipette
npo:NPO_448
NPO_448
<ncicp:ComplexDefinition><ncicp:def-definition>An element of group 1 (IUPAC style) of the periodic table: lithium (Li), sodium (Na), potassium (K), rubidium (Rb), caesium (Cs), and francium (Fr).</ncicp:def-definition></ncicp:ComplexDefinition>
alkali metal
alkali metal
npo:NPO_449
NPO_449
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which has the structure -N=C=S. The group is characteristic of an isothiocyanate compound wherein it is attached to an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
isothiocyanate group
isothiocyanate group
npo:NPO_451
NPO_451
<ncicp:ComplexDefinition><ncicp:def-definition>A covalent linkage where a thioester group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
thioester linkage
thioester linkage
npo:NPO_453
NPO_453
<ncicp:ComplexDefinition><ncicp:def-definition>A nanocantilever which is composed of gold.</ncicp:def-definition></ncicp:ComplexDefinition>
gold nanocantilever
gold nanocantilever
npo:NPO_455
NPO_455
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 46.</ncicp:def-definition></ncicp:ComplexDefinition>
palladium
palladium
npo:NPO_456
NPO_456
<ncicp:ComplexDefinition><ncicp:def-definition>A covalent linkage where a carbamate ester group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
carbamate ester linkage
carbamate linkage
carbamate ester linkage
npo:NPO_457
NPO_457
NCIT: C62386
<ncicp:ComplexDefinition><ncicp:def-definition>A two-dimensional nanoparticle which resembles a fullerene-like nanostructure and exhibits an irregular horn-like shape.</ncicp:def-definition></ncicp:ComplexDefinition>
nanohorn
[NCI_Thesaurus definition]: A fullerene-like nanostructure that consists of graphene cylinders and exhibits an irregular horn-like shape.
nanohorn
70
npo:NPO_458
NPO_458
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 70.</ncicp:def-definition></ncicp:ComplexDefinition>
ytterbium atom
ytterbium atom
npo:NPO_459
NPO_459
<ncicp:ComplexDefinition><ncicp:def-definition>A metal which is any of the following elements: aluminium, bismuth, gallium, indium, lead, hallium, tin.</ncicp:def-definition></ncicp:ComplexDefinition>
other metal
poor metal
other metal
npo:NPO_460
NPO_460
NCIT: C511
<ncicp:ComplexDefinition><ncicp:def-definition>Antineoplastic antimetabolite which interferes with folic acid metabolism by inhibiting one or more folate-dependent enzymes, resulting in decreased DNA, RNA and protein synthesis. It has a chemical structure similar to folic acid, a key component in cell proliferation,</ncicp:def-definition></ncicp:ComplexDefinition>
folate antagonist
antifolate
folate inhibitor
folic acid antagonist
folic acid inhibitor
folate antagonist
npo:NPO_461
NPO_461
NCIT:C64352
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A cylindrical shape inhering in a 3-dimensional object having height greater than the cross-sectional diameter.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
rod-shaped
rodlike
rod-shaped
npo:NPO_463
NPO_463
<ncicp:ComplexDefinition><ncicp:def-definition>An element of Group 18 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
Group 18 Element
noble gas
Group 18 Element
npo:NPO_464
NPO_464
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which is loaded with etoposide.</ncicp:def-definition></ncicp:ComplexDefinition>
etoposide-loaded nanoparticle
etoposide-loaded nanoparticle
npo:NPO_466
NPO_466
<ncicp:ComplexDefinition><ncicp:def-definition>A carboxylic ester linkage which is formed between an organo hydroxy compound and an acid anhydride, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
carboxylic ester linkage between organo hydroxy compound and acid anhydride
carboxylic ester linkage between organo hydroxy compound and acid anhydride
62
npo:NPO_467
NPO_467
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 62.</ncicp:def-definition></ncicp:ComplexDefinition>
samarium atom
samarium atom
npo:NPO_468
NPO_468
<ncicp:ComplexDefinition><ncicp:def-definition>Role that inheres in or borne by an independent continuant at the molecular level in a particular context.</ncicp:def-definition></ncicp:ComplexDefinition>
molecular role
molecular role
npo:NPO_469
NPO_469
<ncicp:ComplexDefinition><ncicp:def-definition>An organic molecule or compound, which consists of two or more amino acids linked by covalent bonding between the amino group of one aminoacid and the carboxyl group of the other.</ncicp:def-definition></ncicp:ComplexDefinition>
peptide
peptide
npo:NPO_470
NPO_470
<ncicp:ComplexDefinition><ncicp:def-definition>Drug that acts in the extracellular matrix</ncicp:def-definition></ncicp:ComplexDefinition>
anticancer drug acting in extracellular matrix
anticancer drug acting in extracellular matrix
npo:NPO_471
NPO_471
<ncicp:ComplexDefinition><ncicp:def-definition>A linkage in which a molecular structure or nanostructure becomes trapped due to non-covalent interactions, in a nanoparticle's material site that is partially bounded by the particle's constituting material.</ncicp:def-definition></ncicp:ComplexDefinition>
entrapment
entrapment
npo:NPO_472
NPO_472
<ncicp:ComplexDefinition><ncicp:def-definition>The hollow core of a nanoshell</ncicp:def-definition></ncicp:ComplexDefinition>
hollow core of nanoshell
hollow core of nanoshell
npo:NPO_473
NPO_473
<ncicp:ComplexDefinition><ncicp:def-definition>Drug that is directed to interfere with the activity of a protein located at the tumor cell.</ncicp:def-definition></ncicp:ComplexDefinition>
drug directed against protein of tumor cell
drug directed against protein of tumor cell
60
npo:NPO_474
NPO_474
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 60.</ncicp:def-definition></ncicp:ComplexDefinition>
neodymium atom
neodymium atom
npo:NPO_475
NPO_475
<ncicp:ComplexDefinition><ncicp:def-definition>An element of a group of elements in the periodic table, which have similar outer shell electronic configurations of their respective atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
group element
group element
npo:NPO_476
NPO_476
NCIT: C582
<ncicp:ComplexDefinition><ncicp:def-definition>A DNA binding agent that is capable of inserting itself between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore preventing its proper functioning.</ncicp:def-definition></ncicp:ComplexDefinition>
DNA intercalating agent
DNA intercalator
DNA intercalating agent
npo:NPO_477
NPO_477
<ncicp:ComplexDefinition><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by ultrasound.</ncicp:def-definition></ncicp:ComplexDefinition>
stimulus of ultrasound
stimulus of ultrasound
npo:NPO_478
NPO_478
<ncicp:ComplexDefinition><ncicp:def-definition>An element in the third row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition>
Period 3 Element
Period 3 Element
109
npo:NPO_480
NPO_480
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 109.</ncicp:def-definition></ncicp:ComplexDefinition>
meitnerium atom
meitnerium atom
npo:NPO_481
NPO_481
<ncicp:ComplexDefinition><ncicp:def-definition>A unilamellar vesicle, which has size less than 100 nm.</ncicp:def-definition></ncicp:ComplexDefinition>
small unilamellar vesicle
small unilamellar vesicle
31
npo:NPO_483
NPO_483
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 31.</ncicp:def-definition></ncicp:ComplexDefinition>
gallium atom
gallium atom
npo:NPO_484
NPO_484
<ncicp:ComplexDefinition><ncicp:def-definition>Surface of a micelle formed from polar head groups of constituting amphiphilic molecules in a polar solvent.</ncicp:def-definition></ncicp:ComplexDefinition>
surface of micelle
surface of micelle
npo:NPO_485
NPO_485
<ncicp:ComplexDefinition><ncicp:def-definition>A flexible molecular part that connects two other parts of the same molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
spacer
spacer arm
[definition source]: Wikipedia
spacer
npo:NPO_486
NPO_486
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 23.</ncicp:def-definition></ncicp:ComplexDefinition>
vanadium
vanadium
npo:NPO_487
NPO_487
MESH:D000964
NCIT:C272
<ncicp:ComplexDefinition><ncicp:def-definition>Antineoplastic agent that inhibits the biosynthesis of pyrimidine or purine nucleotides or mimic natural nucleotides so they interfere with their synthesis or function and subsequently interrupt DNA, RNA, and/or protein synthesis.</ncicp:def-definition></ncicp:ComplexDefinition>
antineoplastic antimetabolite
antimetabolite
antineoplastic antimetabolite
npo:NPO_488
NPO_488
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 110.</ncicp:def-definition></ncicp:ComplexDefinition>
darmstadtium
darmstadtium
npo:NPO_489
NPO_489
PATO:0001536
<ncicp:ComplexDefinition><ncicp:def-definition>A realizable property which inheres in a solid, liquid, or gaseous chemical substance by virtue of a certain amount of the bearer to have the ability to dissolve or not in a certain volume of a liquid solvent to form a homogeneous solution.</ncicp:def-definition></ncicp:ComplexDefinition>
solubility
solubility
npo:NPO_490
NPO_490
<ncicp:ComplexDefinition><ncicp:def-definition>A realizable entity that inheres in a material entity and indicates that the bearer has the ability to produce or elicit an immune response.</ncicp:def-definition></ncicp:ComplexDefinition>
immunogenic
immunogenic
npo:NPO_491
NPO_491
<ncicp:ComplexDefinition><ncicp:def-definition>An intramolecular interaction between positive and negative ions which are formed by the transfer of one or more valence electrons from one atom to another atom.</ncicp:def-definition></ncicp:ComplexDefinition>
ionic bonding
ionic bonding
74
npo:NPO_492
NPO_492
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 74.</ncicp:def-definition></ncicp:ComplexDefinition>
tungsten atom
tungsten atom
npo:NPO_493
NPO_493
NCIT:C18106
<ncicp:ComplexDefinition><ncicp:def-definition>A protein that is located on the cell surface, or in the cytoplasm, and which binds to, or responds to, a ligand with high specificity. [based on source: UniProtKB]</ncicp:def-definition></ncicp:ComplexDefinition>
receptor
receptor
npo:NPO_495
NPO_495
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 81.</ncicp:def-definition></ncicp:ComplexDefinition>
thallium
thallium
npo:NPO_496
NPO_496
<ncicp:ComplexDefinition><ncicp:def-definition>Drug that is directed to interfere with the activity of a protein located in the tumor cell cytoplasm</ncicp:def-definition></ncicp:ComplexDefinition>
drug directed against protein in cytoplasm
drug directed against protein in cytoplasm
73
npo:NPO_497
NPO_497
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 73.</ncicp:def-definition></ncicp:ComplexDefinition>
tantalum atom
tantalum atom
npo:NPO_498
NPO_498
<ncicp:ComplexDefinition><ncicp:def-definition>Magnetic property exhibited in a material only when the material is kept in the presence of an externally applied magnetic field, and the magnetism disappears when the magnetic field is removed. The magnetic moments of the atoms are not aligned, and the behavior causes the material to be attracted to external magnetic fields. This behavior exists only above the Curie or Neel Temperature.</ncicp:def-definition></ncicp:ComplexDefinition>
paramagnetic
paramagnetic
npo:NPO_500
NPO_500
<ncicp:ComplexDefinition><ncicp:def-definition>Solubility which describes the ability of a certain amount of solid, liquid or gaseous chemical substance to dissolve in a certain volume of water solvent.</ncicp:def-definition></ncicp:ComplexDefinition>
solubility in water
water solubility
solubility in water
51
npo:NPO_501
NPO_501
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 51.</ncicp:def-definition></ncicp:ComplexDefinition>
antimony atom
antimony atom
npo:NPO_502
NPO_502
<ncicp:ComplexDefinition><ncicp:def-definition>An amine group which is formally derived by the removal of one hydrogen atom from ammonia, by virtue of which it has the structure -NH2. The group is characteristic of a primary amine molecule wherein it is attached to hydrocarbyl groups.</ncicp:def-definition></ncicp:ComplexDefinition>
primary amine group
primary amine group
npo:NPO_504
NPO_504
<ncicp:ComplexDefinition><ncicp:def-definition>A covalent linkage where a thioether group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
thioether linkage
thioether linkage
npo:NPO_505
NPO_505
<ncicp:ComplexDefinition><ncicp:def-definition>An acyl halide group in which the halogen atom is a fluorine atom.</ncicp:def-definition></ncicp:ComplexDefinition>
acyl fluoride group
acyl fluoride group
npo:NPO_507
NPO_507
<ncicp:ComplexDefinition><ncicp:def-definition>An imine linkage which is formed between a primary amine and an aldehyde, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
imine linkage between primary amine and aldehyde
imine linkage between primary amine and aldehyde
npo:NPO_508
NPO_508
<ncicp:ComplexDefinition><ncicp:def-definition>An amine group which is formally derived by the removal of three hydrogen atoms from ammonia, by virtue of which it has the structure -N(-)-. The group is characteristic of a tertiary amine molecule wherein it is attached to hydrocarbyl groups.</ncicp:def-definition></ncicp:ComplexDefinition>
tertiary amine group
tertiary amine group
npo:NPO_509
NPO_509
<ncicp:ComplexDefinition><ncicp:def-definition>Drug that is directed to affect the tumor endothelial cells.</ncicp:def-definition></ncicp:ComplexDefinition>
anticancer drug directed against endothelium
anticancer drug directed against endothelium
npo:NPO_510
NPO_510
NCIT: C2050
<ncicp:ComplexDefinition><ncicp:def-definition>An endothelial-specific integrin inhibitor that acts by blocking the action of an endothelial cell-surface expressed alpha (v) integrin, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.</ncicp:def-definition></ncicp:ComplexDefinition>
alpha V beta inhibitor
alpha V beta inhibitor
npo:NPO_511
NPO_511
<ncicp:ComplexDefinition><ncicp:def-definition>An acyl compound is an organic compound which is characterized by the presence of an acyl group R-C(=O)-, where R denotes an organic group and the carbon atom is not bonded to a hydrogen atom or oxygen atom.</ncicp:def-definition></ncicp:ComplexDefinition>
acyl compound
acyl compound
96
npo:NPO_513
NPO_513
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 96.</ncicp:def-definition></ncicp:ComplexDefinition>
curium atom
curium atom
npo:NPO_514
NPO_514
<ncicp:ComplexDefinition><ncicp:def-definition>A qualitative measure of solubility in water which indicates that the chemical substance dissolves in water under specific conditions.</ncicp:def-definition></ncicp:ComplexDefinition>
soluble in water
water-soluble
soluble in water
npo:NPO_515
NPO_515
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shape formed by the surface of a 3-dimensional object that tapers from a circular base.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
conical shape
conical
conical shape
npo:NPO_516
NPO_516
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 63.</ncicp:def-definition></ncicp:ComplexDefinition>
europium
europium
npo:NPO_518
NPO_518
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 79.</ncicp:def-definition></ncicp:ComplexDefinition>
gold
Au
gold
npo:NPO_519
NPO_519
<ncicp:ComplexDefinition><ncicp:def-definition>An isocyanate is an organic compound characterized by the presence of isocyanate group. It has the structure R-N=C=O, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
isocyanate compound
isocyanate compound
npo:NPO_520
NPO_520
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 1.</ncicp:def-definition></ncicp:ComplexDefinition>
hydrogen
hydrogen
84
npo:NPO_521
NPO_521
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 84.</ncicp:def-definition></ncicp:ComplexDefinition>
polonium atom
polonium atom
npo:NPO_522
NPO_522
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 51.</ncicp:def-definition></ncicp:ComplexDefinition>
antimony
antimony
npo:NPO_523
NPO_523
<ncicp:ComplexDefinition><ncicp:def-definition>Drug that blocks the extracellular domain of the membrane receptor.</ncicp:def-definition></ncicp:ComplexDefinition>
drug directed against extracellular domain of membrane receptor
drug directed against extracellular domain of membrane receptor
npo:NPO_524
NPO_524
<ncicp:ComplexDefinition><ncicp:def-definition>The shell of a nanocapsule.</ncicp:def-definition></ncicp:ComplexDefinition>
shell of nanocapsule
shell of nanocapsule
77
npo:NPO_525
NPO_525
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 77.</ncicp:def-definition></ncicp:ComplexDefinition>
iridium atom
iridium atom
npo:NPO_526
NPO_526
<ncicp:ComplexDefinition><ncicp:def-definition>A covalent linkage where an imine group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
imine linkage
imine linkage
npo:NPO_528
NPO_528
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle response to internal stimulus, which occurs in response to a change in pH.</ncicp:def-definition></ncicp:ComplexDefinition>
nanoparticle response to pH change
nanoparticle response to pH change
npo:NPO_529
NPO_529
<ncicp:ComplexDefinition><ncicp:def-definition>A metal which is any of the following elements: d-block element or one of the elements in groups 4, 5, 6, 10, 11, 12.</ncicp:def-definition></ncicp:ComplexDefinition>
transition element
transition element
npo:NPO_530
NPO_530
<ncicp:ComplexDefinition><ncicp:def-definition>A maleimide derivative is an imide derived from maleimide by replacing the hydrogen atom bonded to nitrogen in maleimide by an organic group. It is characterized by the presence of a maleimide group.</ncicp:def-definition></ncicp:ComplexDefinition>
maleimide derivative
maleimide derivative
86
npo:NPO_531
NPO_531
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 86.</ncicp:def-definition></ncicp:ComplexDefinition>
radon atom
radon atom
npo:NPO_532
NPO_532
NCIT:C45304
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A mixture in which fine particles are suspended in a fluid where they are supported by buoyancy.</ncicp:def-definition><ncicp:attr>WordNet</ncicp:attr></ncicp:ComplexDefinition>
suspension
suspension
111
npo:NPO_533
NPO_533
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 111.</ncicp:def-definition></ncicp:ComplexDefinition>
roentgenium atom
roentgenium atom
85
npo:NPO_534
NPO_534
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 85.</ncicp:def-definition></ncicp:ComplexDefinition>
astatine atom
astatine atom
34
npo:NPO_535
NPO_535
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 34.</ncicp:def-definition></ncicp:ComplexDefinition>
selenium atom
selenium atom
npo:NPO_536
NPO_536
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which has the structure -C(=N-)-. The group is the characteristic of an imine.</ncicp:def-definition></ncicp:ComplexDefinition>
imine group
imine group
npo:NPO_537
NPO_537
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which has a coating agent composed of a carbohydrate.</ncicp:def-definition></ncicp:ComplexDefinition>
carbohydrate-coated nanoparticle
carbohydrate-coated nanoparticle
66
npo:NPO_538
NPO_538
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 66.</ncicp:def-definition></ncicp:ComplexDefinition>
dysprosium atom
dysprosium atom
14
npo:NPO_541
NPO_541
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 14.</ncicp:def-definition></ncicp:ComplexDefinition>
silicon atom
silicon atom
npo:NPO_542
NPO_542
<ncicp:ComplexDefinition><ncicp:def-definition>Role played by a molecular entity that is used to target a material entity, and the role is realized during the process of molecular targeting.</ncicp:def-definition></ncicp:ComplexDefinition>
targeting role
targeting role
npo:NPO_543
NPO_543
<ncicp:ComplexDefinition><ncicp:def-definition>A unilamellar vesicle, which has size greater than 100 nm.</ncicp:def-definition></ncicp:ComplexDefinition>
large unilamellar vesicle
large unilamellar vesicle
npo:NPO_544
NPO_544
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which has the structure C(=[NH2+])-O-CH3. The group is characteristic of an imidoester compound.</ncicp:def-definition></ncicp:ComplexDefinition>
imidoester group
imidoester group
npo:NPO_549
NPO_549
<ncicp:ComplexDefinition><ncicp:def-definition>Drug directed against a tumor cell to affect its division and function.</ncicp:def-definition></ncicp:ComplexDefinition>
anticancer drug directed against tumor cell
anticancer drug directed against tumor cell
npo:NPO_551
NPO_551
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which is basically composed of poly(amidoamine) dendrimer in which gold quantum dots are entrapped.</ncicp:def-definition></ncicp:ComplexDefinition>
gold quantum dot-entrapped poly(amidoamine) dendrimer nanoparticle
gold quantum dot-entrapped poly(amidoamine) dendrimer nanoparticle
npo:NPO_552
NPO_552
MESH:D000906
NCIT: C16295
<ncicp:ComplexDefinition><ncicp:def-definition>A type of protein made by B lymphocytes in response to a foreign substance (antigen). Each antibody only binds to a specific antigen, helping to destroy the antigen directly or by assisting white blood cells to destroy the antigen.[source: NCI_Thesaurus]</ncicp:def-definition></ncicp:ComplexDefinition>
antibody
antibody
npo:NPO_553
NPO_553
<ncicp:ComplexDefinition><ncicp:def-definition>Magnetic property exhibited in materials which create a weak magnetic field in opposition to an externally applied magnetic field; thus, causing repulsion of the material in a magnetic field.</ncicp:def-definition></ncicp:ComplexDefinition>
diamagnetic
diamagnetic
100
npo:NPO_554
NPO_554
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 100.</ncicp:def-definition></ncicp:ComplexDefinition>
fermium atom
fermium atom
npo:NPO_555
NPO_555
<ncicp:ComplexDefinition><ncicp:def-definition>An element of the periodic table for which, in the atomic ground state, the highest-energy electrons occupy some orbital.</ncicp:def-definition></ncicp:ComplexDefinition>
block element
block element
npo:NPO_556
NPO_556
NCIT:C67437
<ncicp:ComplexDefinition><ncicp:def-definition>Tubulin binding agent that binds to the taxane site of the beta-tubulin subunit, a region described as a binding pocket located within the middle domain and corresponding to an approximate residue sequence of 217-231. Specifically, these agents bind to a cysteine residue within the pocket, which is also the binding site for GTP. Agents binding at the taxane site promote the polymerization of dimers to form a very rigid and stable microtubule structure which is not readily disassembled. Interfering with microtubule dynamics, these agents inhibit the normal turnover process essential during mitosis, thereby causing cell-cycle arrest and/or apoptosis. [source: NCIT]</ncicp:def-definition></ncicp:ComplexDefinition>
taxane-pocket binding agent
taxane-pocket binding agent
49
npo:NPO_557
NPO_557
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 49.</ncicp:def-definition></ncicp:ComplexDefinition>
indium atom
indium atom
npo:NPO_558
NPO_558
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 41.</ncicp:def-definition></ncicp:ComplexDefinition>
niobium
niobium
npo:NPO_560
NPO_560
<ncicp:ComplexDefinition><ncicp:def-definition>A thioyanate compound is an organic compound which is characterized by the presence of a thiocyanate group. It has the structure R-S-C#N, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
thiocyanate compound
thiocyanate
thiocyanate compound
78
npo:NPO_561
NPO_561
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 78.</ncicp:def-definition></ncicp:ComplexDefinition>
platinum atom
platinum atom
npo:NPO_562
NPO_562
<ncicp:ComplexDefinition><ncicp:def-definition>Drug that is directed to affect the synthesis and function of a receptor of an endothelial growth factor.</ncicp:def-definition></ncicp:ComplexDefinition>
anticancer drug directed against endothelial growth factor receptor
anticancer drug directed against endothelial growth factor receptor
npo:NPO_563
NPO_563
<ncicp:ComplexDefinition><ncicp:def-definition>An attachment formed via covalent bonding between chemical groups of molecular entities.</ncicp:def-definition></ncicp:ComplexDefinition>
covalent linkage
covalent attachment
covalent conjugation
covalent linkage
npo:NPO_564
NPO_564
<ncicp:ComplexDefinition><ncicp:def-definition>A process that prevents or inhibits the maturation ,growth or spread of tumor cells.</ncicp:def-definition></ncicp:ComplexDefinition>
antineoplastic activity
antineoplastic activity
npo:NPO_565
NPO_565
<ncicp:ComplexDefinition><ncicp:def-definition>A process, which describes the function or activity of a nanoparticle, occurring in response to a stimulus acting on the nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
nanoparticle response to stimulus
nanoparticle response to stimulus
npo:NPO_566
NPO_566
<ncicp:ComplexDefinition><ncicp:def-definition>An ionizable property inhering in a chemical substance by virtue of having the ability to be ionized and gain a positive charge.</ncicp:def-definition></ncicp:ComplexDefinition>
ionizable to gain positive charge
ionizable to gain positive charge
npo:NPO_567
NPO_567
NCIT:C1967
<ncicp:ComplexDefinition><ncicp:def-definition>A protein kinase inhibitor, which inhibits tyrosine kinase enzyme, involved with the transduction and processing of many extracellular and intracellular signals including cell proliferation.</ncicp:def-definition></ncicp:ComplexDefinition>
tyrosine kinase inhibitor
tyrosine kinase inhibitor
npo:NPO_568
NPO_568
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 26.</ncicp:def-definition></ncicp:ComplexDefinition>
iron
iron
npo:NPO_570
NPO_570
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 111.</ncicp:def-definition></ncicp:ComplexDefinition>
roentgenium
roentgenium
23
npo:NPO_571
NPO_571
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 23.</ncicp:def-definition></ncicp:ComplexDefinition>
vanadium atom
vanadium atom
npo:NPO_572
NPO_572
<ncicp:ComplexDefinition><ncicp:def-definition>Anticancer drug which is directed to interfere with the synthesis, function or activity of mRNA.</ncicp:def-definition></ncicp:ComplexDefinition>
drug directed against tumor RNA
drug directed against tumor RNA
npo:NPO_576
NPO_576
<ncicp:ComplexDefinition><ncicp:def-definition>Role borne by a molecular entity which prevents or slows down an activity or process; or that reduces the activity of another molecular entity.</ncicp:def-definition></ncicp:ComplexDefinition>
inhibitor role
inhibitor role
npo:NPO_577
NPO_577
NCIT:C1723
<ncicp:ComplexDefinition><ncicp:def-definition>A recombinant, chimeric monoclonal antibody directed against the epidermal growth factor receptor (EGFR) with antineoplastic activity. Cetuximab binds to the extracellular domain of the EGFR, thereby preventing the activation and subsequent dimerization of the receptor; the decrease in receptor activation and dimerization may result in an inhibition in signal transduction and anti-proliferative effects. This agent may inhibit EGFR-dependent primary tumor growth and metastasis. EGFR is overexpressed on the cell surfaces of various solid tumors.[source: NCI_Thesaurus]</ncicp:def-definition></ncicp:ComplexDefinition>
cetuximab
Erbitux
drug directed against extracellular domain of membrane receptor
cetuximab
npo:NPO_579
NPO_579
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 59.</ncicp:def-definition></ncicp:ComplexDefinition>
praseodymium
praseodymium
npo:NPO_580
NPO_580
<ncicp:ComplexDefinition><ncicp:def-definition>An imine linkage which is formed between a secondary amine and an aldehyde, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
imine linkage between secondary amine and aldehyde
imine linkage between secondary amine and aldehyde
npo:NPO_582
NPO_582
<ncicp:ComplexDefinition><ncicp:def-definition>An intermolecular interaction between molecules (polar or non-polar) due to attraction between permanent or temporary molecular dipoles.</ncicp:def-definition></ncicp:ComplexDefinition>
dipole-dipole interaction
Van Der Waals Interaction
dipole-dipole interaction
npo:NPO_585
NPO_585
<ncicp:ComplexDefinition><ncicp:def-definition>A polypeptide, which is part of some protein molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
polypeptide chain
polypeptide chain
npo:NPO_586
NPO_586
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 108.</ncicp:def-definition></ncicp:ComplexDefinition>
hassium
hassium
71
npo:NPO_587
NPO_587
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 71.</ncicp:def-definition></ncicp:ComplexDefinition>
lutetium atom
lutetium atom
npo:NPO_589
NPO_589
<ncicp:ComplexDefinition><ncicp:def-definition>A three-dimensional nanoparticle which is made of material that exhibits quantum effects.</ncicp:def-definition></ncicp:ComplexDefinition>
quantum dot
QD
(NCI_Thesaurus definition): Nanometer-sized semiconductor particles, made of cadmium selenide (CdSe), cadmium sulfide (CdS) or cadmium telluride (CdTe) with an inert polymer coating. The semiconductor material used for the core is chosen based upon the emission wavelength range being targeted: CdS for UV-blue, CdSe for the bulk of the visible spectrum, and CdTe for far red and near-infrared. The size of the particle determines the exact color of a given quantum dot. The polymer coating protects cells from cadmium toxicity but also facilitates the attachment of a variety of targeting molecules, including monoclonal antibodies directed to tumor-specific biomarkers. Because of their small size, quantum dots can function as cell- and even molecule-specific markers that will not interfere with the normal cellular functions.
quantum dot
79
npo:NPO_591
NPO_591
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 79.</ncicp:def-definition></ncicp:ComplexDefinition>
gold atom
gold atom
65
npo:NPO_592
NPO_592
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 65.</ncicp:def-definition></ncicp:ComplexDefinition>
terbium atom
terbium atom
npo:NPO_594
NPO_594
<ncicp:ComplexDefinition><ncicp:def-definition>An antineoplastic agent, which inhibits the synthesis of DNA.</ncicp:def-definition></ncicp:ComplexDefinition>
DNA synthesis inhibitor
DNA synthesis inhibitor
npo:NPO_596
NPO_596
MESH: D017319
NCIT: C1420
<ncicp:ComplexDefinition><ncicp:def-definition>An anticancer drug that is pharmacologically inactive but when exposed to ultraviolet light or sunlight, it is converted to its pharmacologically active metabolite.</ncicp:def-definition></ncicp:ComplexDefinition>
photosensitizing agent
photosensitizer
photosensitizing agent
npo:NPO_597
NPO_597
NCIT:C62050
<ncicp:ComplexDefinition><ncicp:def-definition>An organic compound which functions as a topoisomerase-II inhibitor and an antineoplastic antibiotic.</ncicp:def-definition></ncicp:ComplexDefinition>
mitroxantrone
anticancer drug that inhibits protein activity related to DNA synthesis
mitroxantrone
npo:NPO_598
NPO_598
<ncicp:ComplexDefinition><ncicp:def-definition>A qualitative measure of "solubility in water" which indicates the poor ability of the chemical substance to dissolve in water under specific conditions.</ncicp:def-definition></ncicp:ComplexDefinition>
insoluble in water
water-insoluble
insoluble in water
npo:NPO_599
NPO_599
<ncicp:ComplexDefinition><ncicp:def-definition>Role played by a material entity when it is used for labeling another material entity.</ncicp:def-definition></ncicp:ComplexDefinition>
labeling role
labeling role
npo:NPO_601
NPO_601
<ncicp:ComplexDefinition><ncicp:def-definition>A colloid, which is a semi-solid or jelly like material formed by the coagulation of a colloidal liquid.</ncicp:def-definition></ncicp:ComplexDefinition>
gel
gel
npo:NPO_602
NPO_602
<ncicp:ComplexDefinition><ncicp:def-definition>A nanofiber which is composed of graphene layers arranged as stacked cones, cups or plates. Carbon nanofibers with graphene layers wrapped into perfect cylinders are called carbon nanotubes.</ncicp:def-definition></ncicp:ComplexDefinition>
carbon nanofiber
carbon nanofiber
75
npo:NPO_604
NPO_604
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 75.</ncicp:def-definition></ncicp:ComplexDefinition>
rhenium atom
rhenium atom
npo:NPO_605
NPO_605
<ncicp:ComplexDefinition><ncicp:def-definition>The process of directing a molecule or a particle to a specific location in a tumor.</ncicp:def-definition></ncicp:ComplexDefinition>
tumor targeting
tumor targeting
npo:NPO_606
NPO_606
<ncicp:ComplexDefinition><ncicp:def-definition>A nanotube which consists of one or more graphite sheets (graphene) of hexagonal arrays of carbon rolled into seamless cylinders with capped ends.</ncicp:def-definition></ncicp:ComplexDefinition>
carbon nanotube
carbon nanotube
32
npo:NPO_609
NPO_609
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 32.</ncicp:def-definition></ncicp:ComplexDefinition>
germanium atom
germanium atom
18
npo:NPO_610
NPO_610
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 18.</ncicp:def-definition></ncicp:ComplexDefinition>
argon atom
argon atom
npo:NPO_611
NPO_611
<ncicp:ComplexDefinition><ncicp:def-definition>An element of Group 10 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
Group 10 Element
nickel group element
Group 10 Element
npo:NPO_612
NPO_612
<ncicp:ComplexDefinition><ncicp:def-definition>The hollow core region of a nanocage.</ncicp:def-definition></ncicp:ComplexDefinition>
hollow core of nanocage
hollow core of nanocage
51
npo:NPO_613
NPO_613
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 51.</ncicp:def-definition></ncicp:ComplexDefinition>
lead atom
lead atom
npo:NPO_614
NPO_614
<ncicp:ComplexDefinition><ncicp:def-definition>A carbonyl group which is characteristic of a ketone wherein it is attached to two carbon atoms via covalent bonds.</ncicp:def-definition></ncicp:ComplexDefinition>
ketone group
ketone group
npo:NPO_615
NPO_615
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 8.</ncicp:def-definition></ncicp:ComplexDefinition>
oxygen
oxygen
npo:NPO_616
NPO_616
NCIT: C2144
<ncicp:ComplexDefinition><ncicp:def-definition>An angiogenesis inhibitor that acts by blocking the action of endothelial integrins. An endothelial-specific integrin/survival signaling inhibitor binds to and blocks the activity of endothelial-specific integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.</ncicp:def-definition></ncicp:ComplexDefinition>
endothelial-specific integrin inhibitor
survival signaling inhibitor
[definition source]: NCI_Thesaurus
endothelial-specific integrin inhibitor
npo:NPO_617
NPO_617
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle response to stimulus, which occurs in response to the internal stimulus acting on the nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
nanoparticle response to internal stimulus
nanoparticle response to internal stimulus
npo:NPO_618
NPO_618
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which is loaded with paclitaxel.</ncicp:def-definition></ncicp:ComplexDefinition>
paclitaxel-loaded nanoparticle
paclitaxel-loaded nanoparticle
npo:NPO_619
NPO_619
<ncicp:ComplexDefinition><ncicp:def-definition>A three-dimensional nanoparticle with a hollow core and a porous wall or shell. It's structure resembles that of a hollow cage, that is similar to a fullerene type of nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
nanocage
nanocage
npo:NPO_620
NPO_620
NCIT:C25760
<ncicp:ComplexDefinition><ncicp:def-definition>DNA binding agent that is able to covalently bind to DNA causing inter- or intra-stranded cross-linking of DNA. The cross-linking results in misreading of the DNA code and inhibition of DNA synthesis.</ncicp:def-definition></ncicp:ComplexDefinition>
DNA crosslinking agent
DNA crosslinking agent
npo:NPO_621
NPO_621
<ncicp:ComplexDefinition><ncicp:def-definition>A molecule component in dendrimer which repeats to form the branches of a dendrimer.</ncicp:def-definition></ncicp:ComplexDefinition>
dendrimer repeat unit
dendrimer repeat unit
108
npo:NPO_622
NPO_622
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 108.</ncicp:def-definition></ncicp:ComplexDefinition>
hassium atom
hassium atom
7
npo:NPO_623
NPO_623
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 7.</ncicp:def-definition></ncicp:ComplexDefinition>
nitrogen atom
nitrogen atom
npo:NPO_625
NPO_625
<ncicp:ComplexDefinition><ncicp:def-definition>An element of Group 2 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
Group 2 Element
Group 2 Element
npo:NPO_626
NPO_626
<ncicp:ComplexDefinition><ncicp:def-definition>A covalent linkage where an amide group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
amide linkage
amide bond
amide linkage
npo:NPO_627
NPO_627
<ncicp:ComplexDefinition><ncicp:def-definition>A disposition, inhering in any material entity, whose structure or function can be altered by sound.</ncicp:def-definition></ncicp:ComplexDefinition>
acoustic-sensitive
acoustic-sensitive
npo:NPO_628
NPO_628
<ncicp:ComplexDefinition><ncicp:def-definition>A realizable entity that inheres in a molecular entity or group, and that describes the ability of the bearer to be ionized.</ncicp:def-definition></ncicp:ComplexDefinition>
ionizability
ionizability
npo:NPO_630
NPO_630
<ncicp:ComplexDefinition><ncicp:def-definition>An element of Group 9 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
Group 9 Element
cobalt group element
Group 9 Element
npo:NPO_631
NPO_631
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle whuch is basically composed of solidified lipid molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
solid lipid nanoparticle
solid lipid nanoparticle
npo:NPO_633
NPO_633
<ncicp:ComplexDefinition><ncicp:def-definition>Anticancer drug, which is the role of a molecular entity, realized from the kind of biological target where the molecular entity is primarily intended or directed to act.</ncicp:def-definition></ncicp:ComplexDefinition>
anticancer drug based on target
[classification source]: E. Espinosa, P. Zamora, J. Feliu and M. G. Baron, Classification of anticancer drugs-a new system based on therapeutic targets, Cancer Treatment Reviews, 29: 515-523 (2003).
anticancer drug based on target
npo:NPO_634
NPO_634
<ncicp:ComplexDefinition><ncicp:def-definition>Magnetic property exhibited by materials in presence of an external magnetic field and the magnetism is retained for a period even after the magnetic field is removed (magnetic moments of the adjacent atoms are aligned in the same direction at temperatures below the Curie temperature).</ncicp:def-definition></ncicp:ComplexDefinition>
ferromagnetic
ferromagnetic
npo:NPO_635
NPO_635
<ncicp:ComplexDefinition><ncicp:def-definition>A molecule role in nanoparticle, which inheres in a molecular entity that has active end-directed functions/activities and is transported and delivered by the nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
payload agent role
payload agent role
npo:NPO_636
NPO_636
<ncicp:ComplexDefinition><ncicp:def-definition>A three-dimensional nanoparticle which is spherical, porous or non-porous and its diameter is measured in nanometers.</ncicp:def-definition></ncicp:ComplexDefinition>
nanosphere
nanosphere
npo:NPO_637
NPO_637
<ncicp:ComplexDefinition><ncicp:def-definition>An amidine linkage which occurs between a primary amine and an imidoester, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
amidine linkage between primary amine and imidoester
amidine linkage between primary amine and imidoester
npo:NPO_638
NPO_638
<ncicp:ComplexDefinition><ncicp:def-definition>A disposition, inhering in any material entity, whose structure or function can be altered by a stimulus.</ncicp:def-definition></ncicp:ComplexDefinition>
sensitivity to stimulus
sensitivity to stimulus
npo:NPO_639
NPO_639
NCIT:C63807
<ncicp:ComplexDefinition><ncicp:def-definition>A colloid in which both phases are liquids that are immiscible with each other.[source: WordNet 3.0]</ncicp:def-definition></ncicp:ComplexDefinition>
emulsion
[source]: http://www.thefreedictionary.com
emulsion
npo:NPO_640
NPO_640
<ncicp:ComplexDefinition><ncicp:def-definition>An imide is an amide which is characterized by the presence of an imide group. It has the structure R-C(=O)-N(-R')-C(=O)-R", where R, R" denote organic groups, and R' stands for organic group or hydrogen atom.</ncicp:def-definition></ncicp:ComplexDefinition>
imide
imide
npo:NPO_641
NPO_641
<ncicp:ComplexDefinition><ncicp:def-definition>An independent continuant [snap:IndependentContinuant] consisting of a characteristic spatial shape in relation to some arrangement of material entities and of the medium which is enclosed in whole or in part by this characteristic spatial shape. Material site entities are entities that can be occupied by other material entities.</ncicp:def-definition></ncicp:ComplexDefinition>
material site
definition of material site is based on the definition of snap:Site
material site
npo:NPO_642
NPO_642
<ncicp:ComplexDefinition><ncicp:def-definition>A material site which is a cavity or space formed within the core and generation layer (between branches) of a dendrimer. It can be occupied by molecules other than those which chemically make up the dendrimer.</ncicp:def-definition></ncicp:ComplexDefinition>
dendrimer cavity
dendrimer cavity
npo:NPO_643
NPO_643
NCIT:C503
<ncicp:ComplexDefinition><ncicp:def-definition>A fluorescent dye which is used to stain a specimen or a sample in fluorescence microscopy.</ncicp:def-definition></ncicp:ComplexDefinition>
fluorochrome
fluorochrome
npo:NPO_644
NPO_644
<ncicp:ComplexDefinition><ncicp:def-definition>A thioether linkage which occurs between a thiol and an iodoacetyl derivative, through the covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
thioether linkage between thiol and iodoacetyl derivative
thioether linkage between thiol and iodoacetyl derivative
npo:NPO_645
NPO_645
<ncicp:ComplexDefinition><ncicp:def-definition>A semisynthetic derivative of camptothecin, a cytotoxic, quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata.</ncicp:def-definition></ncicp:ComplexDefinition>
topotecan
topotecan
npo:NPO_646
NPO_646
<ncicp:ComplexDefinition><ncicp:def-definition>An atom of fluorine or chlorine or bromine or iodine or astatine.</ncicp:def-definition></ncicp:ComplexDefinition>
halogen atom
halogen atom
npo:NPO_648
NPO_648
<ncicp:ComplexDefinition><ncicp:def-definition>A covalent linkage where an arylthioether group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
arylthioether linkage
arylthioether linkage
npo:NPO_649
NPO_649
<ncicp:ComplexDefinition><ncicp:def-definition>A crosslinking agent which contains two different end reactive groups connected by a spacer, and the two reactive groups can couple to two different functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
heterobifunctional crosslinker
heterobifunctional crosslinker
npo:NPO_650
NPO_650
<ncicp:ComplexDefinition><ncicp:def-definition>An organic compound which is characterized by the presence of a succinimidyl carbonate group.</ncicp:def-definition></ncicp:ComplexDefinition>
succinimidyl carbonate compound
succinimidyl carbonate compound
npo:NPO_651
NPO_651
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 88.</ncicp:def-definition></ncicp:ComplexDefinition>
radium
radium
npo:NPO_652
NPO_652
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 90.</ncicp:def-definition></ncicp:ComplexDefinition>
thorium
thorium
npo:NPO_653
NPO_653
<ncicp:ComplexDefinition><ncicp:def-definition>An internal stimulus for nanoparticle function, which is caused by a change in pH of the medium.</ncicp:def-definition></ncicp:ComplexDefinition>
stimulus of pH change
stimulus of pH change
99
npo:NPO_654
NPO_654
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 99.</ncicp:def-definition></ncicp:ComplexDefinition>
einsteinium atom
einsteinium atom
npo:NPO_655
NPO_655
<ncicp:ComplexDefinition><ncicp:def-definition>An attractive non-covalent interaction between two or more (otherwise non-associated) molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
intermolecular interaction
intermolecular interaction
npo:NPO_656
NPO_656
<ncicp:ComplexDefinition><ncicp:def-definition>An element in the fifth row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition>
Period 5 Element
Period 5 Element
16
npo:NPO_658
NPO_658
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 16.</ncicp:def-definition></ncicp:ComplexDefinition>
sufur atom
sufur atom
npo:NPO_660
NPO_660
<ncicp:ComplexDefinition><ncicp:def-definition>A non-metal which is any of the following elements: argon, helium, krypton, neon, radon, xenon.</ncicp:def-definition></ncicp:ComplexDefinition>
noble gas
inert element
noble gas
npo:NPO_661
NPO_661
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which has a core part and a shell part, and both the core and shell are distinguished by their respective material content.</ncicp:def-definition></ncicp:ComplexDefinition>
core-shell nanoparticle
core-shell nanoparticle
npo:NPO_662
NPO_662
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle response to magnetic field, which involves the release of drugs from a drug-loaded nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
drug release from nanoparticle in response to magnetic field
drug release from nanoparticle in response to magnetic field
npo:NPO_663
NPO_663
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 85.</ncicp:def-definition></ncicp:ComplexDefinition>
astatine
astatine
npo:NPO_664
NPO_664
<ncicp:ComplexDefinition><ncicp:def-definition>An element of Group 8 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
Group 8 Element
iron group element
Group 8 Element
npo:NPO_665
NPO_665
<ncicp:ComplexDefinition><ncicp:def-definition>A nanodevice which has the end-directed activity/function to serve as the simplest micro-electro-mechanical system (MEMS) that is easily machined and mass-produced for probing nanoscale specimens.</ncicp:def-definition></ncicp:ComplexDefinition>
nanocantilever
Nanocantilevers are often used to explore and characterize the surfaces of biological systems. The motion of the device is recorded and transformed mathematically to provide information about these surface characteristics.
nanocantilever
npo:NPO_666
NPO_666
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A polyhedral shape that inheres in a 3-dimensional object having six plane faces.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
hexahedral shape
hexahedral
[source]: WordNet
hexahedral shape
npo:NPO_667
NPO_667
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which has only one external dimension in the nanoscale size range.</ncicp:def-definition></ncicp:ComplexDefinition>
one-dimensional nanoparticle
1-D nanoparticle
one-dimensional nanoparticle
npo:NPO_668
NPO_668
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 52.</ncicp:def-definition></ncicp:ComplexDefinition>
tellurium
tellurium
npo:NPO_669
NPO_669
NCIT: C66829
<ncicp:ComplexDefinition><ncicp:def-definition>A quality that inheres in a molecular entity which does not contain carbon as a principal element (some exceptions exist, e.g., carbon dioxide).</ncicp:def-definition></ncicp:ComplexDefinition>
inorganic
inorganic
npo:NPO_670
NPO_670
NCIT:C45298
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A fluid state of matter having no fixed shape but a fixed volume.</ncicp:def-definition></ncicp:ComplexDefinition>
liquid
liquid
npo:NPO_671
NPO_671
<ncicp:ComplexDefinition><ncicp:def-definition>The exterior surface of a dendrimer formed by the dendrimer's end/surface groups.</ncicp:def-definition></ncicp:ComplexDefinition>
exterior surface of dendrimer
exterior surface of dendrimer
npo:NPO_672
NPO_672
snap:MaterialEntity
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An independent continuant [snap:IndependentContinuant] which is spatially extended and composed of matter. The identity of material entities is independent of that of other entities and can be maintained through time.</ncicp:def-definition></ncicp:ComplexDefinition>
material entity
Matter is any physical substance that has mass and occupies space.
material entity
npo:NPO_673
NPO_673
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 33.</ncicp:def-definition></ncicp:ComplexDefinition>
arsenic
arsenic
npo:NPO_674
NPO_674
<ncicp:ComplexDefinition><ncicp:def-definition>An element in the second row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition>
Period 2 Element
Period 2 Element
npo:NPO_675
NPO_675
<ncicp:ComplexDefinition><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by magnetic field.</ncicp:def-definition></ncicp:ComplexDefinition>
stimulus of magnetic field
stimulus of magnetic field
npo:NPO_677
NPO_677
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which has a coating agent composed of a biopolymer.</ncicp:def-definition></ncicp:ComplexDefinition>
biopolymer-coated nanoparticle
biopolymer-coated nanoparticle
npo:NPO_678
NPO_678
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 78.</ncicp:def-definition></ncicp:ComplexDefinition>
platinum
platinum
43
npo:NPO_679
NPO_679
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 43.</ncicp:def-definition></ncicp:ComplexDefinition>
technetium atom
technetium atom
npo:NPO_682
NPO_682
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which has the structure -C(=O)-O- and it is formally derived from carboxylic acid and organic hydroxy compound. The group is characteristic of a carboxylic ester compound wherein it is attached to two carbon atoms via single covalent bonds.</ncicp:def-definition></ncicp:ComplexDefinition>
carboxylic ester group
carboxylic ester group
npo:NPO_683
NPO_683
<ncicp:ComplexDefinition><ncicp:def-definition>A covalent bonding in which the sharing of electron pair is unequal due to difference in the electronegativities of atoms that share the electron pair.</ncicp:def-definition></ncicp:ComplexDefinition>
polar covalent bonding
polar covalent bonding
npo:NPO_684
NPO_684
NCIT: C62372
<ncicp:ComplexDefinition><ncicp:def-definition>A nanodevice which has the end-directed activity/function to serve as a probing tool of nanometer-size, and combined with a nanosensor, is useful for subcellular detection of activity or phenomenon (e.g. biological phenomenon or process).</ncicp:def-definition></ncicp:ComplexDefinition>
nanoprobe
nanoprobe
npo:NPO_685
NPO_685
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A molecule which is used for targeting other molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
targeting agent
targeting agent
npo:NPO_686
NPO_686
<ncicp:ComplexDefinition><ncicp:def-definition>A fullerene refers to any cagelike, hollow molecule composed of hexagonal and/or pentagonal groups of carbon atoms , and it is regarded as the third form of carbon after diamond and graphite.</ncicp:def-definition></ncicp:ComplexDefinition>
fullerene
fullerene
npo:NPO_687
NPO_687
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which has the structure -O-C(=O)-O-. The group is characteristic of a carbonate ester molecule wherein it is attached to two carbon atoms via single covalent bonds.</ncicp:def-definition></ncicp:ComplexDefinition>
carbonate ester group
carbonate ester group
npo:NPO_688
NPO_688
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 83.</ncicp:def-definition></ncicp:ComplexDefinition>
bismuth
bismuth
npo:NPO_689
NPO_689
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality which inheres in a group of multiple bearers AND specific only to the type of bearers in the group.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
specific collective quality
specific collective quality
26
npo:NPO_690
NPO_690
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 26.</ncicp:def-definition></ncicp:ComplexDefinition>
iron atom
iron atom
npo:NPO_691
NPO_691
NCIT:C62340
<ncicp:ComplexDefinition><ncicp:def-definition>A nanodevice which has the end-directed activity/function to serve as a template consisting of two-dimensional patterning of biological molecules on a surface for biological analysis.</ncicp:def-definition></ncicp:ComplexDefinition>
nanoarray
nanoarray
npo:NPO_694
NPO_694
<ncicp:ComplexDefinition><ncicp:def-definition>An element of Group 3 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
Group 3 Element
scandium group element
Group 3 Element
npo:NPO_695
NPO_695
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular component which is a functional group that is part of a dendrimer and it is located at the surface of a dendrimer.</ncicp:def-definition></ncicp:ComplexDefinition>
dendrimer end group
terminal group
dendrimer end group
npo:NPO_696
NPO_696
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which is formally derived by the removal of one or more hydrogen atoms from ammonia, by virtue of which it has the structure -NH2 or -NH- or -N(-)-. The group is characteristic of an amine molecule wherein it is attached to hydrocarbyl groups.</ncicp:def-definition></ncicp:ComplexDefinition>
amine group
amino group
amine group
npo:NPO_697
NPO_697
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 58.</ncicp:def-definition></ncicp:ComplexDefinition>
cerium
cerium
npo:NPO_699
NPO_699
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle loaded with tamoxifen.</ncicp:def-definition></ncicp:ComplexDefinition>
tamoxifen-loaded nanoparticle
tamoxifen-loaded nanoparticle
npo:NPO_701
NPO_701
<ncicp:ComplexDefinition><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by sound.</ncicp:def-definition></ncicp:ComplexDefinition>
stimulus of sound
stimulus of sound
npo:NPO_702
NPO_702
<ncicp:ComplexDefinition><ncicp:def-definition>An element of Group 12 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
Group 12 Element
zinc group element
Group 12 Element
95
npo:NPO_704
NPO_704
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 95.</ncicp:def-definition></ncicp:ComplexDefinition>
americium atom
americium atom
npo:NPO_705
NPO_705
<ncicp:ComplexDefinition><ncicp:def-definition>A nanodevice which has the end-directed activity/function to serve as an in vivo implantable device, designed to deliver drugs under zero order rate kinetics at high local drug concentrations to non-resectable tumor lesions.</ncicp:def-definition></ncicp:ComplexDefinition>
nanochannel
[definition source]: Lesinski et al, Biomedical Microdevices, vol 7, number 1, 71-79, 2005
nanochannel
20
npo:NPO_706
NPO_706
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 20.</ncicp:def-definition></ncicp:ComplexDefinition>
calcium atom
calcium atom
npo:NPO_707
NPO_707
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A primary particle which has an average size in the nanoscale range; which has an identifiable and definite chemical composition, property or function that uniquely define the nanoparticle's type as known; and, which may or may not exhibit a size-intensive property.</ncicp:def-definition></ncicp:ComplexDefinition>
nanoparticle
Definition is partly based on ASTM E 2456-06 (Terminology for Nanotechnology).
nanoparticle
npo:NPO_708
NPO_708
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 19.</ncicp:def-definition></ncicp:ComplexDefinition>
potassium
potassium
89
npo:NPO_709
NPO_709
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 89.</ncicp:def-definition></ncicp:ComplexDefinition>
actinium atom
actinium atom
15
npo:NPO_710
NPO_710
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 15.</ncicp:def-definition></ncicp:ComplexDefinition>
phosphorus atom
phosphorus atom
npo:NPO_711
NPO_711
<ncicp:ComplexDefinition><ncicp:def-definition>A nanostructured material which is formed by the combination of single-walled carbon nanotubes and fullerenes wherein the fullerenes are covalently bonded to the outer surface of the nanotubes.</ncicp:def-definition></ncicp:ComplexDefinition>
nanobud
[definition source]: Nasibulin, A. G., Peter. V. Pikhitsa, Hua. Jiang, David. P. Brown, A. V. Krasheninnikov, Anton S. Anisimov, Paula Queipo, Anna Moisala, David Gonzalez, Gunther Lientschnig, Abdou Hassanien, Sergey D. Shandakov, Giulio Lolli, Daniel E. Resasco, Mansoo Choi, David Tománek, and Esko I. Kauppinen "A Novel Hybrid Carbon Nanomaterial". Nature Nanotechnology 2(3), 156-161 (2007).
nanobud
npo:NPO_713
NPO_713
<ncicp:ComplexDefinition><ncicp:def-definition>A crosslinker which has two identical reactive ends connected by a carbon chain spacer and are used mostly to crosslink molecules or parts of molecules in a one-step chemical crosslinking procedure.</ncicp:def-definition></ncicp:ComplexDefinition>
homobifunctional crosslinker
homobifunctional crosslinker
npo:NPO_714
NPO_714
<ncicp:ComplexDefinition><ncicp:def-definition>An element of the periodic table of elements.</ncicp:def-definition></ncicp:ComplexDefinition>
periodic table element
periodic table element
npo:NPO_715
NPO_715
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle response to ultrasound, which involves the release of drugs from a drug-loaded nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
drug release from nanoparticle in response to ultrasound
drug release from nanoparticle in response to ultrasound
90
npo:NPO_716
NPO_716
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 90.</ncicp:def-definition></ncicp:ComplexDefinition>
thorium atom
thorium atom
npo:NPO_717
NPO_717
<ncicp:ComplexDefinition><ncicp:def-definition>A stimulus for nanoparticle function, which originates from a source that is outside of the the medium in which the nanoparticle is located.</ncicp:def-definition></ncicp:ComplexDefinition>
external stimulus for nanoparticle function
external stimulus for nanoparticle function
npo:NPO_718
NPO_718
<ncicp:ComplexDefinition><ncicp:def-definition>An element of the periodic table for which, in the atomic ground state, the highest-energy electron is in an s-orbital.</ncicp:def-definition></ncicp:ComplexDefinition>
s-block element
s-block element
npo:NPO_719
NPO_719
<ncicp:ComplexDefinition><ncicp:def-definition>A supramolecular structure which is a closed vesicle that forms on hydration of dry phospholipids above its transition temperature.</ncicp:def-definition></ncicp:ComplexDefinition>
liposome
liposome vesicle
liposome
npo:NPO_720
NPO_720
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which has the structure N#C-O-. The group is characteristic of a cyanate molecule wherein it is attached to an organic group via a single covalent bond.</ncicp:def-definition></ncicp:ComplexDefinition>
cyanate group
cyanate group
npo:NPO_721
NPO_721
MESH:D048271
<ncicp:ComplexDefinition><ncicp:def-definition>A linear polysaccharide of deacetylated beta-1,4-D-glucosamine; deacetylated chitin.</ncicp:def-definition></ncicp:ComplexDefinition>
chitosan
chitosan
46
npo:NPO_722
NPO_722
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 46.</ncicp:def-definition></ncicp:ComplexDefinition>
palladium atom
palladium atom
npo:NPO_723
NPO_723
<ncicp:ComplexDefinition><ncicp:def-definition>A three-dimensional nanoparticle which consists of a nuclear core surrounded by a lighter lipid membrane.</ncicp:def-definition></ncicp:ComplexDefinition>
nanocell
Nanocell was first used for sequential delivery of anti-angiogenesis and chemotherapeutic agent to solid tumors.The chemotherapeutic agent can be conjugated to a nanoparticle in the core, while the anti-angiogenesis agent can be encapsulated in the lipid membrane.It was designed to first cause membrane disruption for release of anti-angiogenesis agent, which causes tumor vascular collapse, and finally cause intra-tumoral trapping of the core chemotherapeutic drug-conjugated nanoparticles.
[definition source]: Sengupta et al, Nature Letters, vol 436, 2005
nanocell
npo:NPO_724
NPO_724
<ncicp:ComplexDefinition><ncicp:def-definition>A three-dimensional nanoparticle which consists of a shell and a space, in which desired substances may be placed. It can be cylindrical or spherical in shape.</ncicp:def-definition></ncicp:ComplexDefinition>
nanocapsule
Nanocapsule
npo:NPO_725
NPO_725
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which has the structure -E(=N-)-NH2, where E could denote carbon (C) or (Sulfur). The group is characteristic of an amidine compound.</ncicp:def-definition></ncicp:ComplexDefinition>
amidine group
amidine group
npo:NPO_726
NPO_726
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 43.</ncicp:def-definition></ncicp:ComplexDefinition>
technetium
technetium
npo:NPO_727
NPO_727
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 93.</ncicp:def-definition></ncicp:ComplexDefinition>
neptunium
neptunium
npo:NPO_728
NPO_728
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality which inheres in a group of multiple bearers AND NOT specific only to the type of bearers in the group.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
general collective quality
general collective quality
npo:NPO_729
NPO_729
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which is basically composed of iron oxide.</ncicp:def-definition></ncicp:ComplexDefinition>
iron oxide nanoparticle
iron oxide nanoparticle
npo:NPO_730
NPO_730
<ncicp:ComplexDefinition><ncicp:def-definition>Buckyball (C60) or Buckministerfullerene, is a type of fullerene which comprises of 60 carbon atoms arranged in interlocking hexagons and pentagons, like the patches on a soccer ball. Its geometry is roughly spherical and it has a hollow interior.</ncicp:def-definition></ncicp:ComplexDefinition>
buckyball
buckyball
npo:NPO_731
NPO_731
<ncicp:ComplexDefinition><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by heat.</ncicp:def-definition></ncicp:ComplexDefinition>
stimulus of heat
stimulus of heat
npo:NPO_732
NPO_732
<ncicp:ComplexDefinition><ncicp:def-definition>A realizable property which inheres in a molecule that has both hydrophobic and hydrophilic parts.</ncicp:def-definition></ncicp:ComplexDefinition>
amphiphilic
amphipathic
amphiphilic
npo:NPO_733
NPO_733
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A pure substance which is made up of one type of atom, and it cannot be decomposed or transformed by a chemical reaction into a different substance, although it can be transmutated into an isotope through a nuclear reaction.</ncicp:def-definition></ncicp:ComplexDefinition>
element
element
npo:NPO_735
NPO_735
MESH:D050091
<ncicp:ComplexDefinition><ncicp:def-definition>A polymeric molecule which has a highly-branched, three-dimensional tree-like architecture, synthesized from monomers where shells of branched molecules are added in discrete steps to a central core.</ncicp:def-definition></ncicp:ComplexDefinition>
dendrimer
[MeSH definition]: Tree-like, highly branched, polymeric compounds. They grow three-dimensionally by the addition of shells of branched molecules to a central core. The overall globular shape and presence of cavities gives potential as drug carriers and CONTRAST AGENTS.
[NCI_THESAURUS definition]: A polymeric molecule which has a highly-branched, three-dimensional architecture. Dendrimers are synthesized from monomers and new branches are added in discrete steps to form a tree-like architecture. A high level of synthetic control is achieved through step-wise reactions and purification at each step to regulate the size, architecture, functionality and monodispersity of the molecules. These polymers have desirable pharmacokinetic properties and a polyvalent array of surface groups that make them potential drug delivery vesicles.
dendrimer
npo:NPO_736
NPO_736
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 47.</ncicp:def-definition></ncicp:ComplexDefinition>
silver
silver
npo:NPO_737
NPO_737
NCIT: C259
<ncicp:ComplexDefinition><ncicp:def-definition>An antineoplastic agent isolated naturally from microorganisms or synthesized chemically that kills or inhibits the growth of tumor cells. Antineoplastic antibiotics can interfere with the normal function of cellular nucleic acids and proteins.</ncicp:def-definition></ncicp:ComplexDefinition>
antineoplastic antibiotic
anticancer antibiotic
antitumor antibiotic
antineoplastic antibiotic
npo:NPO_738
NPO_738
<ncicp:ComplexDefinition><ncicp:def-definition>An amide linkage which is formed between a primary amine and a carboxylic ester.</ncicp:def-definition></ncicp:ComplexDefinition>
amide linkage between primary amine and carboxylic ester
amide linkage between primary amine and carboxylic ester
npo:NPO_739
NPO_739
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 39.</ncicp:def-definition></ncicp:ComplexDefinition>
yttrium
yttrium
npo:NPO_740
NPO_740
<ncicp:ComplexDefinition><ncicp:def-definition>An acyl halide group in which the halogen atom is a "bromine atom."</ncicp:def-definition></ncicp:ComplexDefinition>
acyl bromide group
acyl bromide group
npo:NPO_742
NPO_742
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 50.</ncicp:def-definition></ncicp:ComplexDefinition>
tin
tin
npo:NPO_743
NPO_743
<ncicp:ComplexDefinition><ncicp:def-definition>A dipole-dipole interaction between non-polar molecules due to attraction between an instantaneous dipole on one non-polar molecule and an induced dipole on the other non-polar molecule; the temporary dipole on the latter molecule is induced by the randomly occurring (temporary) instantaneous dipole of the former molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
instantaneous dipole-induced dipole interaction
induced dipole-induced dipole interaction
london force
instantaneous dipole-induced dipole interaction
npo:NPO_744
NPO_744
<ncicp:ComplexDefinition><ncicp:def-definition>An element of Group 11 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
Group 11 Element
copper group element
Group 11 Element
npo:NPO_745
NPO_745
<ncicp:ComplexDefinition><ncicp:def-definition>A covalent linkage where a carboxylic ester group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
carboxylic ester linkage
ester linkage
carboxylic ester linkage
npo:NPO_746
NPO_746
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 54.</ncicp:def-definition></ncicp:ComplexDefinition>
xenon
xenon
npo:NPO_747
NPO_747
<ncicp:ComplexDefinition><ncicp:def-definition>An amide group which has the structure -S(=O)-NH2 or -S(=O)-NH- or -S(=O)-N(-)-. The group is characteristic of a sulfonamide wherein it is attached to organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
sulfonamide group
sulfonamide group
npo:NPO_748
NPO_748
<ncicp:ComplexDefinition><ncicp:def-definition>A covalent linkage where a diazo group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
diazo linkage
diazo linkage
npo:NPO_751
NPO_751
<ncicp:ComplexDefinition><ncicp:def-definition>A process which describes an action or event that triggers a specific function of a nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
stimulus for nanoparticle function
stimulus for nanoparticle function
npo:NPO_752
NPO_752
<ncicp:ComplexDefinition><ncicp:def-definition>A stimulus for nanoparticle function, which originates from a source that is inside the medium in which the nanoparticle is located.</ncicp:def-definition></ncicp:ComplexDefinition>
internal stimulus for nanoparticle function
internal stimulus for nanoparticle function
64
npo:NPO_753
NPO_753
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 64.</ncicp:def-definition></ncicp:ComplexDefinition>
gadolinium atom
gadolinium atom
npo:NPO_754
NPO_754
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 76.</ncicp:def-definition></ncicp:ComplexDefinition>
osmium
osmium
npo:NPO_755
NPO_755
<ncicp:ComplexDefinition><ncicp:def-definition>An element with properties between a metal and a non-metal.</ncicp:def-definition></ncicp:ComplexDefinition>
metalloid
metalloid
npo:NPO_756
NPO_756
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle response to external stimulus, which occurs in response to infrared light.</ncicp:def-definition></ncicp:ComplexDefinition>
nanoparticle response to infrared light
nanoparticle response to infrared light
58
npo:NPO_757
NPO_757
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 58.</ncicp:def-definition></ncicp:ComplexDefinition>
cerium atom
cerium atom
npo:NPO_758
NPO_758
<ncicp:ComplexDefinition><ncicp:def-definition>A halo group in which the halogen atom is a chlorine atom.</ncicp:def-definition></ncicp:ComplexDefinition>
chloro group
chloro group
npo:NPO_759
NPO_759
<ncicp:ComplexDefinition><ncicp:def-definition>A thin layer of nanostructured material.</ncicp:def-definition></ncicp:ComplexDefinition>
nanofilm
nanofilm
npo:NPO_760
NPO_760
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A fiat material part which is a material layer surrounding the core.</ncicp:def-definition><ncicp:Definition_Review_Date>100624</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
shell
shell
48
npo:NPO_761
NPO_761
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 48.</ncicp:def-definition></ncicp:ComplexDefinition>
cadmium atom
cadmium atom
npo:NPO_762
NPO_762
<ncicp:ComplexDefinition><ncicp:def-definition>A nanotube which consists of one or more sheets of hexagonal arrays of silicon rolled into seamless cylinders with capped ends.</ncicp:def-definition></ncicp:ComplexDefinition>
silicon nanotube
silicon nanotube
npo:NPO_763
NPO_763
<ncicp:ComplexDefinition><ncicp:def-definition>A realizable entity inhering in particles (e.g, nanoparticles), which gives the bearer the ability to disperse in an aqueous medium.</ncicp:def-definition></ncicp:ComplexDefinition>
water-dispersible
water-dispersible
npo:NPO_764
NPO_764
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A compound or molecule, in which carbon is the principal element.</ncicp:def-definition></ncicp:ComplexDefinition>
organic compound or molecule
organic compound
organic molecule
organic compound or molecule
npo:NPO_765
NPO_765
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 40.</ncicp:def-definition></ncicp:ComplexDefinition>
zirconium
zirconium
npo:NPO_766
NPO_766
<ncicp:ComplexDefinition><ncicp:def-definition>An intermolecular interaction between an ion and a polar molecule by virtue of an attraction between the ionic charge and a permanent dipole on the polar molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
charge-dipole interaction
the polar molecule has permanent molecular dipole moment.
charge-dipole interaction
npo:NPO_767
NPO_767
<ncicp:ComplexDefinition><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by ultraviolet light.</ncicp:def-definition></ncicp:ComplexDefinition>
stimulus of ultraviolet light
stimulus of ultraviolet light
npo:NPO_768
NPO_768
NCIT:C62343
<ncicp:ComplexDefinition><ncicp:def-definition>A material site which is a nanoscale cavity or channel confined within a membrane or solid matter.</ncicp:def-definition></ncicp:ComplexDefinition>
nanopore
[NCI_Thesaurus definition]: A nanoscale cavity or channel confined within a membrane or solid matter.
nanopore
47
npo:NPO_770
NPO_770
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 47.</ncicp:def-definition></ncicp:ComplexDefinition>
silver atom
silver atom
npo:NPO_771
NPO_771
<ncicp:ComplexDefinition><ncicp:def-definition>A colloidal gel in which water is the dispersion medium.[source: WordNet 2008]</ncicp:def-definition></ncicp:ComplexDefinition>
hydrogel
hydrogel
42
npo:NPO_772
NPO_772
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 42.</ncicp:def-definition></ncicp:ComplexDefinition>
molybdenum atom
molybdenum atom
npo:NPO_773
NPO_773
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 61.</ncicp:def-definition></ncicp:ComplexDefinition>
promethium
promethium
npo:NPO_775
NPO_775
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 65.</ncicp:def-definition></ncicp:ComplexDefinition>
terbium
terbium
npo:NPO_776
NPO_776
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular structure which is a branch of a dendrimer, formed by the dendrimer's repeating units.</ncicp:def-definition></ncicp:ComplexDefinition>
dendrimer branch
dendrimer branch
npo:NPO_778
NPO_778
NCIT: C26044
<ncicp:ComplexDefinition><ncicp:def-definition>A process or mechanism which inhibits tumor angiogenesis.</ncicp:def-definition></ncicp:ComplexDefinition>
tumor angiogenesis inhibition
inhibition of tumor angiogenesis
tumor angiogenic inhibition
tumor angiogenesis inhibition
npo:NPO_779
NPO_779
NCIT: C62374
<ncicp:ComplexDefinition><ncicp:def-definition>A nanodevice which has the end-directed activity/function to serve as a sensor/detector of any activity, phenomenon or molecule, within a nanometer-range resolution; it responds to a stimulus by sending a signal that can be measured.</ncicp:def-definition></ncicp:ComplexDefinition>
nanosensor
nanosensor
npo:NPO_781
NPO_781
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 89.</ncicp:def-definition></ncicp:ComplexDefinition>
actinium
actinium
npo:NPO_782
NPO_782
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 3.</ncicp:def-definition></ncicp:ComplexDefinition>
lithium
lithium
npo:NPO_784
NPO_784
NCIT: C1968
<ncicp:ComplexDefinition><ncicp:def-definition>Topoisomerase inhibitor which either stabilizes DNA-protein complexes damaging DNA (e g., teniposide), or inhibits the catalytic activity of the topoisomerase (e.g., merbarone).</ncicp:def-definition></ncicp:ComplexDefinition>
topoisomerase-II inhibitor
type II topoisomerase inhibitor
topoisomerase-II inhibitor
npo:NPO_785
NPO_785
NCIT:C45299
<ncicp:ComplexDefinition><ncicp:def-definition>A fluid having neither independent shape nor volume and being able to expand indefinitely.[source:NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
gas
gas
npo:NPO_786
NPO_786
<ncicp:ComplexDefinition><ncicp:def-definition>A quality that inheres in a molecule or chemical bond due to the absence of dipole moments.</ncicp:def-definition></ncicp:ComplexDefinition>
non-polar
non-polar
21
npo:NPO_787
NPO_787
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 21.</ncicp:def-definition></ncicp:ComplexDefinition>
scandium atom
scandium atom
npo:NPO_791
NPO_791
<ncicp:ComplexDefinition><ncicp:def-definition>An aminoacid which is aromatic in nature.</ncicp:def-definition></ncicp:ComplexDefinition>
aromatic aminoacid
aromatic aminoacid
npo:NPO_792
NPO_792
<ncicp:ComplexDefinition><ncicp:def-definition>The outer surface of a nanotube to which other molecular entities can be attached. (For example, attachment of fullerene on the surface of carbon nanotube.)</ncicp:def-definition></ncicp:ComplexDefinition>
outer surface of nanotube
outer surface of nanotube
npo:NPO_794
NPO_794
<ncicp:ComplexDefinition><ncicp:def-definition>A cross-linking agent for mediating the conjugation of two molecules by forming a bond between functional groups of the molecule while containing no additional atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
zero-length crosslinker
zero-length crosslinker
npo:NPO_795
NPO_795
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 27.</ncicp:def-definition></ncicp:ComplexDefinition>
cobalt
cobalt
npo:NPO_796
NPO_796
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 16.</ncicp:def-definition></ncicp:ComplexDefinition>
sulfur
sulfur
npo:NPO_797
NPO_797
<ncicp:ComplexDefinition><ncicp:def-definition>A thioether is an organic compound which is characterized by the presence of a thioether group. It has the structure R-S-R', where R, R' denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
thioether
thioether
npo:NPO_799
NPO_799
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 74.</ncicp:def-definition></ncicp:ComplexDefinition>
tungsten
tungsten
npo:NPO_801
NPO_801
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which has a coating agent composed of polyethylene glycol.</ncicp:def-definition></ncicp:ComplexDefinition>
PEGylated nanoparticle
PEG-coated nanoparticle
PEG-modified nanoparticle
poly(ethylene) glycol-coated nanoparticle
PEGylated nanoparticle
npo:NPO_802
NPO_802
NCIT: C63848
<ncicp:ComplexDefinition><ncicp:def-definition>A quality that inheres in a molecular entity which contains carbon as a principal element.</ncicp:def-definition></ncicp:ComplexDefinition>
organic
definition for organic is based on the CHEBI definition for organic compounds (CHEBI:25700)
organic
npo:NPO_803
NPO_803
<ncicp:ComplexDefinition><ncicp:def-definition>A molecule component in dendrimer which forms the core of a dendrimer.</ncicp:def-definition></ncicp:ComplexDefinition>
dendrimer core molecule
core initiator group
dendrimer core molecule
npo:NPO_804
NPO_804
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 28.</ncicp:def-definition></ncicp:ComplexDefinition>
nickel
nickel
69
npo:NPO_806
NPO_806
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 69.</ncicp:def-definition></ncicp:ComplexDefinition>
thulium atom
thulium atom
npo:NPO_807
NPO_807
<ncicp:ComplexDefinition><ncicp:def-definition>An amide linkage which is formed between a primary amine and a carboxylic acid.</ncicp:def-definition></ncicp:ComplexDefinition>
amide linkage between primary amine and carboxylic acid
amide linkage between primary amine and carboxylic acid
33
npo:NPO_808
NPO_808
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 33.</ncicp:def-definition></ncicp:ComplexDefinition>
arsenic atom
arsenic atom
npo:NPO_809
NPO_809
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 104.</ncicp:def-definition></ncicp:ComplexDefinition>
rutherfordium
rutherfordium
22
npo:NPO_810
NPO_810
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 22.</ncicp:def-definition></ncicp:ComplexDefinition>
titanium atom
titanium atom
npo:NPO_811
NPO_811
<ncicp:ComplexDefinition><ncicp:def-definition>An internal stimulus for nanoparticle function, which is caused by a change in temperature.</ncicp:def-definition></ncicp:ComplexDefinition>
stimulus of temperature change
stimulus of temperature change
35
npo:NPO_812
NPO_812
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 35.</ncicp:def-definition></ncicp:ComplexDefinition>
bromine atom
bromine atom
52
npo:NPO_813
NPO_813
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 52.</ncicp:def-definition></ncicp:ComplexDefinition>
tellurium atom
tellurium atom
npo:NPO_815
NPO_815
NCIT:C25278
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical substance which deforms under an applied stress, and conforms to the outline of its container.</ncicp:def-definition></ncicp:ComplexDefinition>
fluid
fluid
npo:NPO_816
NPO_816
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 44.</ncicp:def-definition></ncicp:ComplexDefinition>
ruthenium
ruthenium
npo:NPO_818
NPO_818
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 30.</ncicp:def-definition></ncicp:ComplexDefinition>
zinc
zinc
110
npo:NPO_819
NPO_819
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 110.</ncicp:def-definition></ncicp:ComplexDefinition>
darmstadtium atom
darmstadtium atom
npo:NPO_821
NPO_821
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a collection of objects based on size or molecular weights (e.g., particles, polymers).</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
polydispersity
polydispersity
npo:NPO_822
NPO_822
<ncicp:ComplexDefinition><ncicp:def-definition>An amide group which has the structure -P(=O)-NH2 or -P(=O)-NH- or -P(=O)-N(-)-. The group is characteristic of a phosphoramide wherein it is attached to organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
phosphoramide group
phosphoramide group
npo:NPO_823
NPO_823
NCIT:C20401
<ncicp:ComplexDefinition><ncicp:def-definition>An antibody produced by a clone or genetically homogenous fast-growing cells i.e., hybridoma. Hybridoma cells are cloned to establish cell lines producing a specific antibody that is chemically and immunologically homogeneous.[source: NCI_Thesaurus]</ncicp:def-definition></ncicp:ComplexDefinition>
monoclonal antibody
MAb
monoclonal antibody
npo:NPO_824
NPO_824
<ncicp:ComplexDefinition><ncicp:def-definition>A amide group which has the structure -C(=O)-NH2 or -C(=O)-NH- or -C(=O)-N(-)-. The group is characteristic of a carboxamide wherein it is attached to organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
carboxamide group
carboxamide group
npo:NPO_825
NPO_825
<ncicp:ComplexDefinition><ncicp:def-definition>A halo group in which the halogen atom is a fluorine atom.</ncicp:def-definition></ncicp:ComplexDefinition>
fluoro group
fluoro group
npo:NPO_827
NPO_827
<ncicp:ComplexDefinition><ncicp:def-definition>A chemical component in a nanoparticle formulation, which is there to modify the nanoparticle's surface properties like surface charge or surface hydrophilicity; or 2) to which other molecular entities can be attached for facilitating linkage between the molecular entities and the nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
nanoparticle surface modifying agent
coating agent
surface modifying agent
npo:NPO_829
NPO_829
<ncicp:ComplexDefinition><ncicp:def-definition>A supramolecular structure which is an aggregate of amphiphilic molecules in a polar solvent.</ncicp:def-definition></ncicp:ComplexDefinition>
micelle
micelle
npo:NPO_830
NPO_830
<ncicp:ComplexDefinition><ncicp:def-definition>Role played by a material entity that serves as the target for a targeting agent in a targeting process.</ncicp:def-definition></ncicp:ComplexDefinition>
target role
role of a target
target role
npo:NPO_831
NPO_831
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group derived by the removal of a hydrogen atom from a carboxylic acid, by virtue of which it has structure -C(=O)-[O-]. The group is characteristic of a carboxylate compound wherein it is attached to the remaining part of the molecule via a covalent bond between the oxygen atom and a carbon atom.</ncicp:def-definition></ncicp:ComplexDefinition>
carboxylate group
carboxylate group
npo:NPO_833
NPO_833
<ncicp:ComplexDefinition><ncicp:def-definition>The porous shell of a nanocage.</ncicp:def-definition></ncicp:ComplexDefinition>
porous shell of nanocage
porous shell of nanocage
npo:NPO_834
NPO_834
<ncicp:ComplexDefinition><ncicp:def-definition>A substance which has an ordered 3-dimensional structure due to the closely packed arrangement of constituting atoms, molecules or ions. As a result, the substance has a definite shape and volume, and the shape can be modified under application of a force.</ncicp:def-definition></ncicp:ComplexDefinition>
solid
solid
npo:NPO_835
NPO_835
NCIT:C73489
<ncicp:ComplexDefinition><ncicp:def-definition>A colloid that has a continuous liquid phase in which a solid is suspended in a liquid.[source: WordNet 2008]</ncicp:def-definition></ncicp:ComplexDefinition>
sol
sol
npo:NPO_836
NPO_836
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which has a biodegradable property.</ncicp:def-definition></ncicp:ComplexDefinition>
biodegradable nanoparticle
biodegradable nanoparticle
npo:NPO_837
NPO_837
<ncicp:ComplexDefinition><ncicp:def-definition>A passive targeting process, which results in the accumulation of particulate substances in angiogenic tumors due to enhanced permeability of particles across leaky tumor endothelium and retention of the particles inside the tumor due to its defective lymphatic drainage system.</ncicp:def-definition></ncicp:ComplexDefinition>
enhanced permeability and retention effect
EPR
targeting of cancer cells via EPR
[definition source]: Y. Matsumur and H. Maeda, A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent Smancs, Cancer Research, 46, 6387-6392 (1986).
enhanced permeability and retention effect
npo:NPO_841
NPO_841
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 18.</ncicp:def-definition></ncicp:ComplexDefinition>
argon
argon
npo:NPO_842
NPO_842
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 95.</ncicp:def-definition></ncicp:ComplexDefinition>
americium
americium
npo:NPO_843
NPO_843
<ncicp:ComplexDefinition><ncicp:def-definition>A covalent linkage where an arylamine group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
arylamine linkage
arylamine linkage
npo:NPO_844
NPO_844
<ncicp:ComplexDefinition><ncicp:def-definition>An isothiocyanate is an organic compound which is characterized by the presence of an isothiocyanate group. It has the structure R-N=C=S, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
isothiocyanate
isothiocyanate
npo:NPO_845
NPO_845
<ncicp:ComplexDefinition><ncicp:def-definition>An element of the periodic table for which, in the atomic ground state, the highest-energy electrons occupy p-orbitals.</ncicp:def-definition></ncicp:ComplexDefinition>
p-block element
p-block element
npo:NPO_846
NPO_846
MESH:D003911
<ncicp:ComplexDefinition><ncicp:def-definition>A glucan which is a high-molecular-weight polymer of d-glucose, produced by enzymes on the cell surface of certain lactic acid bacteria.</ncicp:def-definition></ncicp:ComplexDefinition>
dextran
dextran
npo:NPO_847
NPO_847
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 94.</ncicp:def-definition></ncicp:ComplexDefinition>
plutonium
plutonium
npo:NPO_848
NPO_848
<ncicp:ComplexDefinition><ncicp:def-definition>A peptide which consists of several aminoacids .</ncicp:def-definition></ncicp:ComplexDefinition>
polypeptide
polypeptide
npo:NPO_849
NPO_849
<ncicp:ComplexDefinition><ncicp:def-definition>An element in the seventh row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition>
Period 7 Element
Period 7 Element
npo:NPO_850
NPO_850
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shape formed by a closed, curve whose path is traced by a point moving in a plane such that the sum of its respective distances from two fixed points (the ellipse's foci) is constant.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
elliptical shape
elliptical
[definition based on source]:http://www.cycfoundation.org, http://www.thefreedictionary.com, NCI
elliptical shape
npo:NPO_851
NPO_851
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 100.</ncicp:def-definition></ncicp:ComplexDefinition>
fermium
fermium
npo:NPO_852
NPO_852
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A rod shape inhering in a long and slender rod, which resembles a needle.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
needle shape
needle shape
npo:NPO_854
NPO_854
NCIT:C63390
<ncicp:ComplexDefinition><ncicp:def-definition>A gas that is a solid or liquid at normal room temperature. [source:NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
vapor
vapor
npo:NPO_855
NPO_855
<ncicp:ComplexDefinition><ncicp:def-definition>An aminoacid which is aliphatic in nature.</ncicp:def-definition></ncicp:ComplexDefinition>
aliphatic aminoacid
aliphatic aminoacid
97
npo:NPO_856
NPO_856
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 97.</ncicp:def-definition></ncicp:ComplexDefinition>
berkelium atom
berkelium atom
npo:NPO_857
NPO_857
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 6.</ncicp:def-definition></ncicp:ComplexDefinition>
carbon
carbon
npo:NPO_858
NPO_858
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shape inhering in a 3-dimensional object that resembles a solid figure bounded by plane polyons or faces.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
polyhedral shape
polyhedral
[source]: WordNet
polyhedral shape
npo:NPO_859
NPO_859
<ncicp:ComplexDefinition><ncicp:def-definition>Magnetic property -similar to paramagnetism - which is exhibited in materials when the temperature of the material is below the Curie temperature.</ncicp:def-definition></ncicp:ComplexDefinition>
superparamagnetic
superparamagnetic
npo:NPO_861
NPO_861
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A regular hexahedral shape that inheres in a 3-dimensional object having six equal squares as faces.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
cubical shape
cubical
[source]:WordNet
cubical shape
54
npo:NPO_862
NPO_862
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 54.</ncicp:def-definition></ncicp:ComplexDefinition>
xenon atom
xenon atom
67
npo:NPO_863
NPO_863
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 67.</ncicp:def-definition></ncicp:ComplexDefinition>
holmium atom
holmium atom
npo:NPO_864
NPO_864
<ncicp:ComplexDefinition><ncicp:def-definition>Topoisomerase inhibitor which inhibits the action of topoisomerase I.</ncicp:def-definition></ncicp:ComplexDefinition>
topoisomerase-I inhibitor
topoisomerase-I inhibitor
29
npo:NPO_865
NPO_865
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 29.</ncicp:def-definition></ncicp:ComplexDefinition>
copper atom
copper atom
npo:NPO_866
NPO_866
<ncicp:ComplexDefinition><ncicp:def-definition>An acryloyl compound is an "organic compound" which is characterized by the presence of an "acryloyl group". It has the structure R-C(=O)-CH=CH2, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
acryloyl compound
acryloyl derivative
acryloyl compound
npo:NPO_867
NPO_867
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A qualitative measure of polydispersity, inhering in a collection of particles that are of different sizes or of polymers that have varying molecular weights.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
polydisperse
polydisperse
npo:NPO_868
NPO_868
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A nanomaterial which is a particulate chemical substance that is formulated systematically using nanotechnology, and it contains nanoparticles and active chemical components/ingredients.</ncicp:def-definition></ncicp:ComplexDefinition>
nanoparticle formulation
Nanotechnology involves the application of scientific knowledge from multidisciplinary fields of science and engineering, towards understanding, manipulating and controlling the properties of matter at the nanoscale (1-100 nm) size dimensions.
nanoparticle formulation
4
npo:NPO_869
NPO_869
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 4.</ncicp:def-definition></ncicp:ComplexDefinition>
beryllium atom
beryllium atom
npo:NPO_870
NPO_870
NCIT: C62387
<ncicp:ComplexDefinition><ncicp:def-definition>A nanohorn that is comprised of a single layer of graphitic carbon and exhibits an irregular horn-like shape. One of the primary characteristics of carbon nanohorns is their ability to aggregate. This aggregation is advantageous because of the resulting enhanced permeability in both gases and liquids.</ncicp:def-definition></ncicp:ComplexDefinition>
single-walled nanohorn
[definition source]: NCI_Thesaurus
single-walled nanohorn
npo:NPO_871
NPO_871
<ncicp:ComplexDefinition><ncicp:def-definition>An element in the fourth row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition>
Period 4 Element
Period 4 Element
98
npo:NPO_872
NPO_872
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 98.</ncicp:def-definition></ncicp:ComplexDefinition>
californium atom
californium atom
npo:NPO_873
NPO_873
NCIT:C2196
<ncicp:ComplexDefinition><ncicp:def-definition>An antineoplastic agent, which prevents or impairs tumor metastasis.</ncicp:def-definition></ncicp:ComplexDefinition>
antimetastatic agent
antimetastatic agent
npo:NPO_874
NPO_874
NCIT:C633
<ncicp:ComplexDefinition><ncicp:def-definition>An L-phenylalanine nitrogen mustard.</ncicp:def-definition></ncicp:ComplexDefinition>
melphalan
anticancer drug that induces breakage of DNA helix
melphalan
npo:NPO_876
NPO_876
NCIT:C2153
<ncicp:ComplexDefinition><ncicp:def-definition>Enzyme inhibitor that inhibits dihydrofolate reductase by interfering with the conversion of Dihydrofolate to Tetrahydrofolate, causing inhibition of nucleotide biosynthesis and protein synthesis.</ncicp:def-definition></ncicp:ComplexDefinition>
dihydrofolate reductase inhibitor
dihydrofolate reductase inhibitor
6
npo:NPO_877
NPO_877
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 6.</ncicp:def-definition></ncicp:ComplexDefinition>
carbon atom
carbon atom
npo:NPO_878
NPO_878
<ncicp:ComplexDefinition><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by visible light.</ncicp:def-definition></ncicp:ComplexDefinition>
stimulus of visible light
stimulus of visible light
npo:NPO_880
NPO_880
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 42.</ncicp:def-definition></ncicp:ComplexDefinition>
molybdenum
molybdenum
npo:NPO_881
NPO_881
<ncicp:ComplexDefinition><ncicp:def-definition>Core part of a micelle formed by hydrophobic (non-polar) tails of individual amphiphilic molecules that form the whole micelle in a polar solvent, which has void spaces to include other hydrophobic molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
hydrophobic core of micelle
hydrophobic core of micelle
106
npo:NPO_885
NPO_885
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 106.</ncicp:def-definition></ncicp:ComplexDefinition>
seaborgium atom
seaborgium atom
npo:NPO_886
NPO_886
<ncicp:ComplexDefinition><ncicp:def-definition>An dipole-dipole interaction between two polar molecules due to attraction between their permanent dipoles.</ncicp:def-definition></ncicp:ComplexDefinition>
permanent dipole-dipole interaction
permanent dipole-dipole interaction
npo:NPO_887
NPO_887
<ncicp:ComplexDefinition><ncicp:def-definition>A disulfide linkage which is formed between two thiol compounds, through covalent interactions between atoms of respective sulfhydryl groups.</ncicp:def-definition></ncicp:ComplexDefinition>
disulfide linkage between two thiols
disulfide linkage between two thiols
npo:NPO_888
NPO_888
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality, which is the physical condition of a material entity, based on its chemical composition and structure.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
physical state
state of matter
physical state
npo:NPO_889
NPO_889
<ncicp:ComplexDefinition><ncicp:def-definition>An amine group which is formally derived by the removal of two hydrogen atoms from ammonia, by virtue of which it has the structure -NH-. The group is characteristic of a secondary amine molecule wherein it is attached to hydrocarbyl groups.</ncicp:def-definition></ncicp:ComplexDefinition>
secondary amine group
secondary amine group
npo:NPO_891
NPO_891
<ncicp:ComplexDefinition><ncicp:def-definition>An amide linkage which is formed between a primary amine and an acyl azide.</ncicp:def-definition></ncicp:ComplexDefinition>
amide linkage between primary amine and acyl azide
amide linkage between primary amine and acyl azide
npo:NPO_892
NPO_892
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A qualitative measure of polydispersity, inhering in a collection of particles that are of the same size or of polymers that have uniform distribution of molecular weights.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
monodisperse
monodisperse
npo:NPO_893
NPO_893
<ncicp:ComplexDefinition><ncicp:def-definition>A two-dimensional nano-object which is an elongated fiber of diameter less than 100 nm.</ncicp:def-definition></ncicp:ComplexDefinition>
nanofiber
nanofiber
npo:NPO_894
NPO_894
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which has the structure -C(=O)-O-C(=O)-. The group is characteristic of acid anhydrides.</ncicp:def-definition></ncicp:ComplexDefinition>
acid anhydride group
The structure of an acid anhydride is R-C(=O)-O-C(=O)-R', in which two acyl groups are bonded to the same oxygen atom; and , R,R' denote hydrogen atoms or organic groups.
acid anhydride group
npo:NPO_895
NPO_895
NCIT:C61303
<ncicp:ComplexDefinition><ncicp:def-definition>A solid which is formed by the solidification of a chemical and having a highly regular atomic structure.</ncicp:def-definition></ncicp:ComplexDefinition>
crystal
crystalline solid
crystal
56
npo:NPO_897
NPO_897
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 56.</ncicp:def-definition></ncicp:ComplexDefinition>
barium atom
barium atom
npo:NPO_898
NPO_898
<ncicp:ComplexDefinition><ncicp:def-definition>An organic compound in which a halogen atom is bonded to a carbon atom that is part of an aromatic ring. It is characterized by the presence of aryl halide groups.</ncicp:def-definition></ncicp:ComplexDefinition>
aryl halide
aryl halide
npo:NPO_899
NPO_899
NCIT:C16956
<ncicp:ComplexDefinition><ncicp:def-definition>A biological process having an abnormal or deleterious effect at the subcellular, cellular, multicellular, or organismal level. (NCI)</ncicp:def-definition></ncicp:ComplexDefinition>
pathologic process
pathologic process
npo:NPO_901
NPO_901
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 2.</ncicp:def-definition></ncicp:ComplexDefinition>
helium
helium
npo:NPO_903
NPO_903
<ncicp:ComplexDefinition><ncicp:def-definition>The process in which material entities (e.g., nanoparticles) are targeted to tumor sites, cancer cells or intracellular organelles in cancer cells, with the help of molecular agents (conjugated to the material entities) that recognize and bind to specific biological molecules at the target location.</ncicp:def-definition></ncicp:ComplexDefinition>
active targeting
active targeting
npo:NPO_904
NPO_904
<ncicp:ComplexDefinition><ncicp:def-definition>Receptor mediated endocytosis, which is the process by which cells internalize folate molecules that specifically bind to folate receptors.</ncicp:def-definition></ncicp:ComplexDefinition>
folate receptor mediated endocytosis
folate receptor mediated endocytosis
npo:NPO_905
NPO_905
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which has all three external dimensions in the nanoscale size range.</ncicp:def-definition></ncicp:ComplexDefinition>
three-dimensional nanoparticle
3-D nanoparticle
three-dimensional nanoparticle
npo:NPO_907
NPO_907
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 11.</ncicp:def-definition></ncicp:ComplexDefinition>
sodium
sodium
npo:NPO_909
NPO_909
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which has a three-membered cyclic ether structure, where an oxygen atom is attached to two carbon atoms and the carbon atoms are bonded to each other via single covalent bond.</ncicp:def-definition></ncicp:ComplexDefinition>
epoxide group
oxirane group
epoxide group
npo:NPO_911
NPO_911
<ncicp:ComplexDefinition><ncicp:def-definition>An element in the sixth row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition>
Period 6 Element
Period 6 Element
npo:NPO_914
NPO_914
NCIT: C29895
<ncicp:ComplexDefinition><ncicp:def-definition>A process which inhibits or blocks the induction, promotion, maintenance, or completion of cell division in cancer cells.</ncicp:def-definition></ncicp:ComplexDefinition>
inhibition of cancer cell growth
inhibition of cancer cell growth
npo:NPO_915
NPO_915
NCIT:C45302
<ncicp:ComplexDefinition><ncicp:def-definition>A solid which corresponds to tiny loose particles, produced by pulverization.</ncicp:def-definition></ncicp:ComplexDefinition>
powder
powder
npo:NPO_916
NPO_916
<ncicp:ComplexDefinition><ncicp:def-definition>A liposome vesicle that has a single lipid bilayer.</ncicp:def-definition></ncicp:ComplexDefinition>
unilamellar vesicle
unilamellar vesicle
npo:NPO_917
NPO_917
<ncicp:ComplexDefinition><ncicp:def-definition>Drug directed to interfere with the activity of a membrane protein receptor of the tumor cell.</ncicp:def-definition></ncicp:ComplexDefinition>
drug directed against membrane receptor
drug directed against membrane receptor
npo:NPO_918
NPO_918
<ncicp:ComplexDefinition><ncicp:def-definition>A contrast agent, which provides contrast in images captured using acoustic imaging techniques.</ncicp:def-definition></ncicp:ComplexDefinition>
acoustic imaging contrast agent
acoustic imaging contrast agent
npo:NPO_919
NPO_919
<ncicp:ComplexDefinition><ncicp:def-definition>An activity, which involves the killing of tumor cells; or which causes reduction of tumor size.</ncicp:def-definition></ncicp:ComplexDefinition>
antitumor activity
antitumor activity
npo:NPO_920
NPO_920
NCIT:C1556
<ncicp:ComplexDefinition><ncicp:def-definition>Antineoplastic antimetabolite which affects the metabolism and utilization of purines.</ncicp:def-definition></ncicp:ComplexDefinition>
purine antagonist
purine inhibitor
purine antagonist
npo:NPO_921
NPO_921
<ncicp:ComplexDefinition><ncicp:def-definition>A process by which cells internalize molecules by the inward budding of plasma membrane vesicles containing proteins with receptor sites specific to the molecules being internalized.</ncicp:def-definition></ncicp:ComplexDefinition>
receptor mediated endocytosis
receptor mediated endocytosis
npo:NPO_922
NPO_922
<ncicp:ComplexDefinition><ncicp:def-definition>A reagent containing ends reactive to specific functional groups on molecules for modifying and linking molecules together.</ncicp:def-definition></ncicp:ComplexDefinition>
crosslinking reagent
crosslinker
crosslinking agent
crosslinking reagent
npo:NPO_924
NPO_924
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 22.</ncicp:def-definition></ncicp:ComplexDefinition>
titanium
titanium
npo:NPO_925
NPO_925
NCIT:C61363
<ncicp:ComplexDefinition><ncicp:def-definition>A solid which corresponds to any small grainlike particle.</ncicp:def-definition></ncicp:ComplexDefinition>
granule
granule
npo:NPO_926
NPO_926
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle response to infrared light, which involves the generation of heat.</ncicp:def-definition></ncicp:ComplexDefinition>
heat generation in response to stimulus of infrared light
heat generation in response to stimulus of infrared light
npo:NPO_927
NPO_927
<ncicp:ComplexDefinition><ncicp:def-definition>An acyl azide is an acyl compound which is characterized by the presence of acyl azide group. It has the structure R-C(=O)-[N+]#N, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
acyl azide
acyl azide derivative
acyl azide
npo:NPO_928
NPO_928
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 68.</ncicp:def-definition></ncicp:ComplexDefinition>
erbium
erbium
npo:NPO_929
NPO_929
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 21.</ncicp:def-definition></ncicp:ComplexDefinition>
scandium
scandium
npo:NPO_932
NPO_932
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 70.</ncicp:def-definition></ncicp:ComplexDefinition>
ytterbium
ytterbium
npo:NPO_933
NPO_933
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 36.</ncicp:def-definition></ncicp:ComplexDefinition>
krypton
krypton
24
npo:NPO_934
NPO_934
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 24.</ncicp:def-definition></ncicp:ComplexDefinition>
chromium atom
chromium atom
27
npo:NPO_935
NPO_935
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 27.</ncicp:def-definition></ncicp:ComplexDefinition>
cobalt atom
cobalt atom
npo:NPO_936
NPO_936
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 57.</ncicp:def-definition></ncicp:ComplexDefinition>
lanthanum
lanthanum
npo:NPO_937
NPO_937
<ncicp:ComplexDefinition><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by infrared light.</ncicp:def-definition></ncicp:ComplexDefinition>
stimulus of infrared light
stimulus of infrared light
npo:NPO_938
NPO_938
<ncicp:ComplexDefinition><ncicp:def-definition>A realizable entity that inheres in a material entity and indicates that the bearer has the ability to be harmless to biological systems.</ncicp:def-definition></ncicp:ComplexDefinition>
biocompatible
biocompatible
npo:NPO_939
NPO_939
NCIT: C2842
<ncicp:ComplexDefinition><ncicp:def-definition>Antineoplastic agent that binds to DNA to regulate mechanisms central to cellular function, including DNA replication and gene expression.</ncicp:def-definition></ncicp:ComplexDefinition>
DNA binding agent
DNA binding agent
npo:NPO_940
NPO_940
<ncicp:ComplexDefinition><ncicp:def-definition>A chemical interaction which is non-covalent in nature and provides the force to hold molecules or parts of molecules together.</ncicp:def-definition></ncicp:ComplexDefinition>
non-covalent interaction
non-covalent bonding
non-covalent interaction
npo:NPO_942
NPO_942
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 102.</ncicp:def-definition></ncicp:ComplexDefinition>
nobelium
nobelium
npo:NPO_943
NPO_943
<ncicp:ComplexDefinition><ncicp:def-definition>A single-walled nanotube which consists of a single graphite layer or sheet of hexagonal arrays of carbon, rolled into a seamless cylinder with a diameter close to 1 nanometer.</ncicp:def-definition></ncicp:ComplexDefinition>
single-walled carbon nanotube
SWCNT
single-walled carbon nanotube
npo:NPO_944
NPO_944
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which has the structure R-C(=O)-X, where R denotes an organic group and X, a halogen atom. The group is characteristic of an acyl halide.</ncicp:def-definition></ncicp:ComplexDefinition>
acyl halide group
Prefix: haloformyl- ; Suffix: -oyl halide
acyl halide group
npo:NPO_945
NPO_945
<ncicp:ComplexDefinition><ncicp:def-definition>A physiologically-dependent process by which a material entity reaches tumor sites, cancer cells or intracellular organelles in cancer cells.</ncicp:def-definition></ncicp:ComplexDefinition>
passive targeting
passive targeting
91
npo:NPO_946
NPO_946
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 91.</ncicp:def-definition></ncicp:ComplexDefinition>
protactinium atom
protactinium atom
npo:NPO_948
NPO_948
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 34.</ncicp:def-definition></ncicp:ComplexDefinition>
selenium
selenium
npo:NPO_949
NPO_949
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which has a coating agent composed of dextran.</ncicp:def-definition></ncicp:ComplexDefinition>
dextran-coated nanoparticle
dextran-coated nanoparticle
npo:NPO_950
NPO_950
<ncicp:ComplexDefinition><ncicp:def-definition>An organic quality inhering in a chemical substance due to the presence of cyclic or acyclic, saturated or unsaturated carbon compounds, but with the exclusion of aromatic quality.</ncicp:def-definition></ncicp:ComplexDefinition>
aliphatic
Definition of aliphatic is based on the CHEBI definition for aliphatic compounds (CHEBI:33653)
aliphatic
npo:NPO_951
NPO_951
<ncicp:ComplexDefinition><ncicp:def-definition>A quality that inheres in a molecule or chemical bond due to the presence or absence of dipole moments.</ncicp:def-definition></ncicp:ComplexDefinition>
polarity
polarity
npo:NPO_952
NPO_952
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 92.</ncicp:def-definition></ncicp:ComplexDefinition>
uranium
uranium
npo:NPO_954
NPO_954
<ncicp:ComplexDefinition><ncicp:def-definition>An ionizable property inhering in a chemical substance by virtue of having the ability to be ionized and gain a negative charge.</ncicp:def-definition></ncicp:ComplexDefinition>
ionizable to gain negative charge
ionizable to gain negative charge
81
npo:NPO_955
NPO_955
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 81.</ncicp:def-definition></ncicp:ComplexDefinition>
thalium atom
thalium atom
npo:NPO_956
NPO_956
<ncicp:ComplexDefinition><ncicp:def-definition>An epoxide compound is an organic compound which is characterized by the presence of an epoxide group. It has the structure R-C1H-CH2-O1, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
epoxide compound
epoxide derivative
epoxide compound
npo:NPO_957
NPO_957
<ncicp:ComplexDefinition><ncicp:def-definition>An internal stimulus for nanoparticle function, which is caused by a change in pO2.</ncicp:def-definition></ncicp:ComplexDefinition>
stimulus of pO2 change
stimulus of pO2 change
102
npo:NPO_960
NPO_960
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 102.</ncicp:def-definition></ncicp:ComplexDefinition>
nobelium atom
nobelium atom
npo:NPO_961
NPO_961
<ncicp:ComplexDefinition><ncicp:def-definition>Drug directed against the DNA in a tumor cell to inhibit DNA replication.</ncicp:def-definition></ncicp:ComplexDefinition>
anticancer drug that induces breakage of DNA helix
anticancer drug that induces breakage of DNA helix
npo:NPO_962
NPO_962
<ncicp:ComplexDefinition><ncicp:def-definition>A covalent bonding in which the sharing of electron pair is equal.</ncicp:def-definition></ncicp:ComplexDefinition>
non-polar covalent bonding
occurs for covalent bond between similar types of atoms or between atoms that have almost zero electronegativity difference.
non-polar covalent bonding
npo:NPO_963
NPO_963
<ncicp:ComplexDefinition><ncicp:def-definition>A spacer, which can be cleaved in response to a change in pH of the solution containing that spacer.</ncicp:def-definition></ncicp:ComplexDefinition>
pH-sensitive linker
pH-sensitive spacer
pH-sensitive linker
npo:NPO_965
NPO_965
<ncicp:ComplexDefinition><ncicp:def-definition>A dendrimer which contains amide molecules as branches; tertiary amines as branching points and primary amine groups as the terminal or end groups.</ncicp:def-definition></ncicp:ComplexDefinition>
poly(amidoamine) dendrimer
PAMAM dendrimer
poly(amidoamine) dendrimer
94
npo:NPO_966
NPO_966
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 94.</ncicp:def-definition></ncicp:ComplexDefinition>
plutonium atom
plutonium atom
68
npo:NPO_967
NPO_967
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 68.</ncicp:def-definition></ncicp:ComplexDefinition>
erbium atom
erbium atom
8
npo:NPO_968
NPO_968
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 8.</ncicp:def-definition></ncicp:ComplexDefinition>
oxygen atom
oxygen atom
npo:NPO_969
NPO_969
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group derived by replacing the =O of an aldehyde or a ketone group with =N-NH2 or =N-NH-R'. It has the structure -C(=N-NH2)- or -C(=N-NH-)-, and the group is characteristic of a hydrazone.</ncicp:def-definition></ncicp:ComplexDefinition>
hydrazone group
hydrazone group
npo:NPO_970
NPO_970
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 96.</ncicp:def-definition></ncicp:ComplexDefinition>
curium
curium
npo:NPO_972
NPO_972
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 69.</ncicp:def-definition></ncicp:ComplexDefinition>
thulium
thulium
npo:NPO_973
NPO_973
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material entity which is one of two or more forms of atoms - of a chemical element-that contain the same number of protons but different number of neutrons in their nuclei. Hence an isotope differs from an atom in relative atomic mass and physical properties but not in chemical properties; an isotope is a radioactive form of element.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
isotope
isotope
npo:NPO_975
NPO_975
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle response to pH change, which involves the release of drugs from a drug-loaded nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
drug release from nanoparticle in response to pH change
drug release from nanoparticle in response to pH change
npo:NPO_976
NPO_976
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 48.</ncicp:def-definition></ncicp:ComplexDefinition>
cadmium
cadmium
12
npo:NPO_977
NPO_977
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 12.</ncicp:def-definition></ncicp:ComplexDefinition>
magnesium atom
magnesium atom
63
npo:NPO_978
NPO_978
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 63.</ncicp:def-definition></ncicp:ComplexDefinition>
europium atom
europium atom
npo:NPO_979
NPO_979
<ncicp:ComplexDefinition><ncicp:def-definition>An element of Group 7 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
Group 7 Element
manganese group element
Group 7 Element
104
npo:NPO_980
NPO_980
<ncicp:ComplexDefinition><ncicp:def-definition>An atom with atomic number 104.</ncicp:def-definition></ncicp:ComplexDefinition>
rutherfordium atom
rutherfordium atom
npo:NPO_981
NPO_981
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 71.</ncicp:def-definition></ncicp:ComplexDefinition>
lutetium
lutetium
npo:NPO_983
NPO_983
<ncicp:ComplexDefinition><ncicp:def-definition>A heterobifunctional crosslinker, which has an amine-reactive group at one end and a sulfhydryl-reactive group at the other end.</ncicp:def-definition></ncicp:ComplexDefinition>
amine-reactive and sulfhydryl-reactive crosslinker
amine-reactive and sulfhydryl-reactive crosslinker
npo:NPO_985
NPO_985
<ncicp:ComplexDefinition><ncicp:def-definition>A disposition inhering in any material entity, whose structure or function can be altered by changes in temperature.</ncicp:def-definition></ncicp:ComplexDefinition>
temperature-sensitive
temperature-sensitive
npo:NPO_986
NPO_986
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which contains a carboxylic ester bound to a primary or secondary or tertiary amine group. The group is characteristic of a carbamate ester compound.</ncicp:def-definition></ncicp:ComplexDefinition>
carbamate ester group
carbamate ester group
npo:NPO_987
NPO_987
<ncicp:ComplexDefinition><ncicp:def-definition>A covalent linkage where a disulfide group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
disulfide linkage
disulfide linkage
npo:NPO_988
NPO_988
<ncicp:ComplexDefinition><ncicp:def-definition>A thioether linkage which occurs between a thiol and an aziridine derivative, through the covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
thioether linkage between thiol and aziridine derivative
thioether linkage between thiol and aziridine derivative
npo:NPO_989
NPO_989
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 35.</ncicp:def-definition></ncicp:ComplexDefinition>
bromine
bromine
npo:NPO_990
NPO_990
<ncicp:ComplexDefinition><ncicp:def-definition>An acyl halide group in which the halogen atom is an iodine atom.</ncicp:def-definition></ncicp:ComplexDefinition>
acyl iodide group
acyl iodide group
npo:NPO_991
NPO_991
<ncicp:ComplexDefinition><ncicp:def-definition>An element with atomic number 72.</ncicp:def-definition></ncicp:ComplexDefinition>
hafnium
hafnium
npo:Retired_Concept_Current_Year
NHC50003
Retired_Concept_Current_Year
This is in support of the NCI Edit Tab Retired and Preretire functions
Retired_Concept_Current_Year
npo:Retired_Concepts
NHC50002
Retired_Concepts
This is in support of the NCI Edit Tab Retired and Preretire functions
Retired_Concepts
CHEBI:CHEBI_15356
NPO_384
CHEBI:15356
<ncicp:ComplexDefinition><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-SH)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
cysteine
2-amino-3-sulfanylpropanoic acid
Cys
cysteine
CHEBI:CHEBI_15377
NPO_1561
CHEBI:15377
<ncicp:ComplexDefinition><ncicp:def-definition>An oxygen hydride which is a liquid and has the chemical formula H2O</ncicp:def-definition></ncicp:ComplexDefinition>
water
water
CHEBI:CHEBI_15428
NPO_800
CHEBI:15428
<ncicp:ComplexDefinition><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH2-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
glycine
Gln
aminoacetic acid
glycine
CHEBI:CHEBI_15858
NPO_1046
CHEBI:15858
<ncicp:ComplexDefinition><ncicp:def-definition>An anion of bromine.</ncicp:def-definition></ncicp:ComplexDefinition>
bromide
bromide
CHEBI:CHEBI_15986
NPO_1000
CHEBI:15986
<ncicp:ComplexDefinition><ncicp:def-definition>A biopolymer composed of nucleotide monomers which are covalently bonded in a long chain.</ncicp:def-definition></ncicp:ComplexDefinition>
polynucleotide
polynucleotide
CHEBI:CHEBI_16042
NPO_1045
CHEBI:16042
<ncicp:ComplexDefinition><ncicp:def-definition>An anion of halogen element.</ncicp:def-definition></ncicp:ComplexDefinition>
halide anion
halide anion
CHEBI:CHEBI_16382
NPO_1049
CHEBI:16382
<ncicp:ComplexDefinition><ncicp:def-definition>An anion of iodine.</ncicp:def-definition></ncicp:ComplexDefinition>
iodide
iodide
CHEBI:CHEBI_16449
NPO_540
CHEBI:16449
<ncicp:ComplexDefinition><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH3)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
alanine
2-aminopropanoic acid
Ala
alanine
CHEBI:CHEBI_16811
NPO_158
CHEBI:16811
<ncicp:ComplexDefinition><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-CH2-S-CH3)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
methionine
Met
methionine
CHEBI:CHEBI_17051
NPO_1048
CHEBI:17051
<ncicp:ComplexDefinition><ncicp:def-definition>An anion of fluorine.</ncicp:def-definition></ncicp:ComplexDefinition>
fluoride
fluoride
CHEBI:CHEBI_17087
NPO_879
CHEBI:17087
<ncicp:ComplexDefinition><ncicp:def-definition>A ketone is a carbonyl compound wherein the carbonyl group is bonded to two carbon atoms. It is characterized by the presence of a ketone group, and therefore, has the structure R-C(=O)-R', where R,R' stand for organic groups and not hydrogen atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
ketone
ketone
CHEBI:CHEBI_17102
NPO_116
CHEBI:17102
<ncicp:ComplexDefinition><ncicp:def-definition>A phosphoramide is an amide characterized by the presence of a phosphoramide group. It has the structure R-P(=O)-NH2, R-P(=O)-NH-R' or R-P(=O)-N(-R")-R', where R,R',R" denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
phosphoramide
phosphoramide
CHEBI:CHEBI_17478
NPO_415
CHEBI:17478
<ncicp:ComplexDefinition><ncicp:def-definition>An aldehyde is a carbonyl compound wherein the carbonyl group is bonded to one hydrogen atom, and one organic group or another hydrogen atom. It is characterized by the presence of an aldehyde group, and has the structure R-C(=O)H, where R denotes an organic group or a hydrogen atom.</ncicp:def-definition></ncicp:ComplexDefinition>
aldehyde
prefix: aldo-
suffix: -al
aldehyde
CHEBI:CHEBI_17497
NPO_1558
CHEBI:17497
<ncicp:ComplexDefinition><ncicp:def-definition>An organic compound which has the formula (OH)CH2-C(OH)=O.</ncicp:def-definition></ncicp:ComplexDefinition>
glycolic acid
glycolic acid
CHEBI:CHEBI_17822
NPO_494
CHEBI:17822
<ncicp:ComplexDefinition><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-OH)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
serine
2-amino-3-hydroxypropanoic acid
Ser
serine
CHEBI:CHEBI_17996
NPO_1047
CHEBI:17996
<ncicp:ComplexDefinition><ncicp:def-definition>An anion of chlorine.</ncicp:def-definition></ncicp:ComplexDefinition>
chloride
chloride
CHEBI:CHEBI_18154
NPO_912
CHEBI:18154
<ncicp:ComplexDefinition><ncicp:def-definition>A biopolymer which consists of large numbers of monosaccharide residues linked glycosidically.</ncicp:def-definition></ncicp:ComplexDefinition>
polysaccharide
glycan
This term is commonly used only for those polysaccharides that contain more than ten monosaccharide residues.
[definition source]: CHEBI
polysaccharide
CHEBI:CHEBI_18186
NPO_906
CHEBI:18186
<ncicp:ComplexDefinition><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(Cc1ccc(O)cc1)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
tyrosine
Try
tyrosine
CHEBI:CHEBI_18237
NPO_974
CHEBI:18237
<ncicp:ComplexDefinition><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2CH2C(OH)=O)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
glutamic acid
2-aminopentanedioic acid
Glu
glutamic acid
CHEBI:CHEBI_18420
NPO_1056
CHEBI:18420
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic dication of magnesium.</ncicp:def-definition></ncicp:ComplexDefinition>
magnesium (2+) ion
magnesium (2+) ion
CHEBI:CHEBI_22221
NPO_302
CHEBI:22221
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which is derived by the removal of one or more hydroxyl groups from an oxoacid. It has the structure R-C(=O)-, where R denotes an organic substituent from the oxoacid.</ncicp:def-definition></ncicp:ComplexDefinition>
acyl group
alkanoyl group
acyl group
CHEBI:CHEBI_22323
NPO_931
CHEBI:22323
<ncicp:ComplexDefinition><ncicp:def-definition>A hydrocarbyl group which is derived from an alkane by removal of a hydrogen atom from any carbon atom.</ncicp:def-definition></ncicp:ComplexDefinition>
alkyl group
Alkyl group is a substituent group from alkane.
alkyl group
CHEBI:CHEBI_22563
NPO_1030
CHEBI:22563
<ncicp:ComplexDefinition><ncicp:def-definition>An ion which is negatively charged.</ncicp:def-definition></ncicp:ComplexDefinition>
anion
anion
CHEBI:CHEBI_22632
NPO_1094
CHEBI:22632
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of arsenic.</ncicp:def-definition></ncicp:ComplexDefinition>
arsenic molecular entity
arsenic molecular entity
CHEBI:CHEBI_22653
NPO_452
CHEBI:22653
<ncicp:ComplexDefinition><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2CH(NH)=O)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
asparagine
2,4-diamino-4-oxobutanoic acid
Asn
asparagine
CHEBI:CHEBI_22660
NPO_853
CHEBI:22660
<ncicp:ComplexDefinition><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2CH(OH)=O)-C(OH)=OH</ncicp:def-definition></ncicp:ComplexDefinition>
aspartic acid
2-aminobutanedioic acid
Asp
aspartic acid
CHEBI:CHEBI_22907
NPO_839
CHEBI:22907
<ncicp:ComplexDefinition><ncicp:def-definition>A glycopeptide, which is isolated from fungus; and with iron, it forms complexes that reduce molecular oxygen to superoxide.</ncicp:def-definition></ncicp:ComplexDefinition>
bleomycin
drug targeted against tumor DNA
bleomycin
CHEBI:CHEBI_22916
NPO_1104
CHEBI:22916
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of boron.</ncicp:def-definition></ncicp:ComplexDefinition>
boron molecular entity
boron molecular entity
CHEBI:CHEBI_22928
NPO_1089
CHEBI:22928
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of bromine.</ncicp:def-definition></ncicp:ComplexDefinition>
bromine molecular entity
bromine molecular entity
CHEBI:CHEBI_22978
NPO_1124
CHEBI:22978
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of cadmium.</ncicp:def-definition></ncicp:ComplexDefinition>
cadmium molecular entity
cadmium molecular entity
CHEBI:CHEBI_23003
NPO_828
CHEBI:23003
<ncicp:ComplexDefinition><ncicp:def-definition>A carbamate ester is an organic compound which is characterized by the presence of a carbamate ester group. It has the structure R-O-C(=O)-NH2 or R-O-C(=O)-NH-R' or R-O-C(=O)-N(-R")-R', where R, R', R" denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
carbamate ester
carbamate ester
CHEBI:CHEBI_23008
NPO_423
CHEBI:23008
MESH: D002241
NCIT: C344
<ncicp:ComplexDefinition><ncicp:def-definition>The generic term 'carbohydrate' includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more terminal groups to carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom, an amino group, a thiol group or similar heteroatomic groups. It also includes derivatives of these compounds. The term 'sugar' is frequently applied to monosaccharides and lower oligosaccharides. Cyclitols are generally not regarded as carbohydrates.</ncicp:def-definition></ncicp:ComplexDefinition>
carbohydrate
[definition source]: CHEBI
carbohydrate
CHEBI:CHEBI_23019
NPO_750
CHEBI:23019
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which has the structure -C(=O)-. The group is characteristic of a carbonyl compound wherein it is attached to the remaining part of the molecule via single covalent bonds.</ncicp:def-definition></ncicp:ComplexDefinition>
carbonyl group
carbonyl group
CHEBI:CHEBI_23117
NPO_1090
CHEBI:23117
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of chlorine.</ncicp:def-definition></ncicp:ComplexDefinition>
chlorine molecular entity
chlorine molecular entity
CHEBI:CHEBI_23237
NPO_1126
CHEBI:23237
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of chromium.</ncicp:def-definition></ncicp:ComplexDefinition>
chromium molecular entity
chromium molecular entity
CHEBI:CHEBI_23367
NPO_355
CHEBI:23367
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A molecular entity is any molecule, ion, ion pair, radical ion, complex, conformer,etc., identifiable as a separately distinguishable entity.</ncicp:def-definition></ncicp:ComplexDefinition>
molecular entity
molecular entity
CHEBI:CHEBI_23377
NPO_1131
CHEBI:23377
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of copper.</ncicp:def-definition></ncicp:ComplexDefinition>
copper molecular entity
copper molecular entity
CHEBI:CHEBI_23849
NPO_659
CHEBI:23849
<ncicp:ComplexDefinition><ncicp:def-definition>A terpenoid which has a C20 skeleton.</ncicp:def-definition></ncicp:ComplexDefinition>
diterpenoid
diterpenoid
CHEBI:CHEBI_23905
NPO_1035
CHEBI:23905
<ncicp:ComplexDefinition><ncicp:def-definition>An anion which consists of a single atom.</ncicp:def-definition></ncicp:ComplexDefinition>
monoatomic anion
monoatomic anion
CHEBI:CHEBI_23906
NPO_1039
CHEBI:23906
<ncicp:ComplexDefinition><ncicp:def-definition>A cation which consists of a single atom.</ncicp:def-definition></ncicp:ComplexDefinition>
monoatomic cation
monoatomic cation
CHEBI:CHEBI_24062
NPO_1091
CHEBI:24062
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of fluorine.</ncicp:def-definition></ncicp:ComplexDefinition>
fluorine molecular entity
fluorine molecular entity
CHEBI:CHEBI_24396
NPO_482
CHEBI:24396
<ncicp:ComplexDefinition><ncicp:def-definition>A peptide compound in which a carbohydrate component is linked to a peptide component.</ncicp:def-definition></ncicp:ComplexDefinition>
glycopeptide
glycopeptide
CHEBI:CHEBI_24431
NPO_392
CHEBI:24431
<ncicp:ComplexDefinition><ncicp:def-definition>A quality inhering in a molecular entity or part thereof, by virtue of its chemical composition and/or connectivity between its constituent atoms; or a complex composition of other molecular entities.</ncicp:def-definition></ncicp:ComplexDefinition>
molecular structure
molecular structure
CHEBI:CHEBI_24433
NPO_303
CHEBI:24433
<ncicp:ComplexDefinition><ncicp:def-definition>A group is a defined linked collection of atoms or a single atom within a molecular entity.</ncicp:def-definition></ncicp:ComplexDefinition>
group
group
CHEBI:CHEBI_24471
NPO_1084
CHEBI:24471
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of a halogen (Group-17) element.</ncicp:def-definition></ncicp:ComplexDefinition>
halogen molecular entity
halogen molecular entity
CHEBI:CHEBI_24532
NPO_692
CHEBI:24532
<ncicp:ComplexDefinition><ncicp:def-definition>A cyclic organic compound, which has ring members that are atoms of carbon and at least of one other element such as sulfur, oxygen or nitrogen.</ncicp:def-definition></ncicp:ComplexDefinition>
organic heterocyclic compound
organic heterocyclic compound
CHEBI:CHEBI_24651
NPO_1145
CHEBI:24651
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A compound which contains a hydroxy group or salts containing hydroxide (OH(-)).</ncicp:def-definition></ncicp:ComplexDefinition>
hydroxide
hydroxide
CHEBI:CHEBI_24783
NPO_734
CHEBI:24783
<ncicp:ComplexDefinition><ncicp:def-definition>An imine is an organic compound which is characterized by the presence of a carbon-nitrogen double bond, and has the structure R-C(=N-R")-R', where at least one of R,R',R" is a hydrocarbyl group while the remaining being hydrogen atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
imine
imine
CHEBI:CHEBI_24834
NPO_1036
CHEBI:24834
<ncicp:ComplexDefinition><ncicp:def-definition>An anion which is inorganic.</ncicp:def-definition></ncicp:ComplexDefinition>
inorganic anion
inorganic anion
CHEBI:CHEBI_24835
NPO_1027
CHEBI:24835
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains no carbon.</ncicp:def-definition></ncicp:ComplexDefinition>
inorganic molecular entity
inorganic molecular entity
CHEBI:CHEBI_24860
NPO_1092
CHEBI:24860
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of iodine.</ncicp:def-definition></ncicp:ComplexDefinition>
iodine molecular entity
iodine molecular entity
CHEBI:CHEBI_24866
NPO_1146
CHEBI:24866
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical compound which is formed by ionic interactions between cations and anions.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
salt
ionic compound
salt
CHEBI:CHEBI_24867
NPO_1034
CHEBI:24867
<ncicp:ComplexDefinition><ncicp:def-definition>An ion which consists of a single atom.</ncicp:def-definition></ncicp:ComplexDefinition>
monoatomic ion
monoatomic ion
CHEBI:CHEBI_24870
NPO_546
CHEBI:24870
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical entity which carries a net electric charge.</ncicp:def-definition></ncicp:ComplexDefinition>
ion
[definition source]: ChEBI
ion
CHEBI:CHEBI_24873
NPO_1134
CHEBI:24873
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of iron.</ncicp:def-definition></ncicp:ComplexDefinition>
iron molecular entity
iron molecular entity
CHEBI:CHEBI_24898
NPO_902
CHEBI:24898
<ncicp:ComplexDefinition><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH(CH3)-CH2-CH3)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
isoleucine
Ile
isoleucine
CHEBI:CHEBI_24913
NPO_387
CHEBI:24913
<ncicp:ComplexDefinition><ncicp:def-definition>Any lipid which is formally derived from isoprene (2-methylbuta-1,3-diene), the skeleton of which can generally be discerned in repeated occurrence in the molecule. The skeleton of isoprenoids may differ from strict additivity of isoprene units by loss or shift of a fragment, commonly a methyl group. The class includes both hydrocarbons and oxygenated derivatives.</ncicp:def-definition></ncicp:ComplexDefinition>
isoprenoid
isoprenoid
CHEBI:CHEBI_25017
NPO_285
CHEBI:25017
<ncicp:ComplexDefinition><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-CH(CH3)-CH3)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
leucine
2-amino-4-methylpentanoic acid
Leu
leucine
CHEBI:CHEBI_25094
NPO_265
CHEBI:25094
<ncicp:ComplexDefinition><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-CH2-CH2-CH2-NH2)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
lysine
2,6-diaminohexanoic acid
Lys
lysine
CHEBI:CHEBI_25154
NPO_1136
CHEBI:25154
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of manganese.</ncicp:def-definition></ncicp:ComplexDefinition>
manganese molecular entity
manganese molecular entity
CHEBI:CHEBI_25196
NPO_1125
CHEBI:25196
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of mercury.</ncicp:def-definition></ncicp:ComplexDefinition>
mercury molecular entity
mercury molecular entity
CHEBI:CHEBI_25213
NPO_1052
CHEBI:25213
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic cation of a metal.</ncicp:def-definition></ncicp:ComplexDefinition>
metal cation
metal cation
CHEBI:CHEBI_25357
NPO_352
CHEBI:25357
<ncicp:ComplexDefinition><ncicp:def-definition>A quinone which is an aziridine-containing compound isolated from Streptomyces lavendulae.</ncicp:def-definition></ncicp:ComplexDefinition>
mitomycin
mitomycin
CHEBI:CHEBI_25362
NPO_1028
CHEBI:25362
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A molecule which consists of atoms of the same element.</ncicp:def-definition></ncicp:ComplexDefinition>
homoatomic molecule
homoatomic molecule
CHEBI:CHEBI_25370
NPO_1127
CHEBI:25370
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of molybdenum.</ncicp:def-definition></ncicp:ComplexDefinition>
molybdenum molecular entity
molybdenum molecular entity
CHEBI:CHEBI_25414
NPO_1054
CHEBI:25414
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic cation which has ionic charge 1+.</ncicp:def-definition></ncicp:ComplexDefinition>
monoatomic monocation
monoatomic monocation
CHEBI:CHEBI_25430
NPO_1063
CHEBI:25430
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic cation which has ionic charge greater than 2+.</ncicp:def-definition></ncicp:ComplexDefinition>
monoatomic polycation
monoatomic polycation
CHEBI:CHEBI_25679
NPO_680
CHEBI:25679
<ncicp:ComplexDefinition><ncicp:def-definition>A compound in which monosaccharide units are joined by glycosidic linkages. The term is commonly used to refer to a defined structure as opposed to a polymer of unspecified length or a homologous mixture. When the linkages are of other types the compounds are regarded as oligosaccharide analogues.</ncicp:def-definition></ncicp:ComplexDefinition>
oligosaccharide
[definition source]: CHEBI
oligosaccharide
CHEBI:CHEBI_25696
NPO_1037
CHEBI:25696
<ncicp:ComplexDefinition><ncicp:def-definition>An anion which is organic.</ncicp:def-definition></ncicp:ComplexDefinition>
organic anion
organic anion
CHEBI:CHEBI_25697
NPO_1041
CHEBI:25697
<ncicp:ComplexDefinition><ncicp:def-definition>A cation which is organic.</ncicp:def-definition></ncicp:ComplexDefinition>
organic cation
organic cation
CHEBI:CHEBI_25698
NPO_230
CHEBI:25698
<ncicp:ComplexDefinition><ncicp:def-definition>An ether is an organic compound in which an oxygen atom is covalently bound to two carbon atoms. It has the structure R-O-R', where R, R' denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
ether
ether
CHEBI:CHEBI_25699
NPO_1031
CHEBI:25699
<ncicp:ComplexDefinition><ncicp:def-definition>An ion which is organic.</ncicp:def-definition></ncicp:ComplexDefinition>
organic ion
organic ion
CHEBI:CHEBI_25741
NPO_1147
CHEBI:25741
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical compound of oxygen with other chemical elements.</ncicp:def-definition></ncicp:ComplexDefinition>
oxide
oxide
CHEBI:CHEBI_25806
NPO_1099
CHEBI:25806
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of oxygen.</ncicp:def-definition></ncicp:ComplexDefinition>
oxygen molecular entity
oxygen molecular entity
CHEBI:CHEBI_26082
NPO_1095
CHEBI:26082
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of phosphorus.</ncicp:def-definition></ncicp:ComplexDefinition>
phosphorus molecular entity
phosphorus molecular entity
CHEBI:CHEBI_26188
NPO_789
CHEBI:26188
<ncicp:ComplexDefinition><ncicp:def-definition>A ketone which is a natural compound containing alternating carbonyl and methylene groups ('?-polyketones'), biogenetically derived from repeated condensation of acetyl coenzyme A (via malonyl coenzyme A); or another compound derived from it by further condensations.</ncicp:def-definition></ncicp:ComplexDefinition>
polyketide
polyketide
CHEBI:CHEBI_2634
NPO_309
CHEBI:2634
<ncicp:ComplexDefinition><ncicp:def-definition>An amidine is an organic compound which is derived from an oxoacid RnE(=O)OH by replacing the hydroxyl group by an amino group and the oxo group by =NR. R stands for a hydrogen atom or organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
amidine
amidine
CHEBI:CHEBI_26373
NPO_900
CHEBI:26373
<ncicp:ComplexDefinition><ncicp:def-definition>An organic heterobicyclic compound which is composed partly or wholly of a pteridine ring system (a pyrimidine ring fused with a pyrazine ring).</ncicp:def-definition></ncicp:ComplexDefinition>
pteridine compound
pteridine compound
CHEBI:CHEBI_26374
NPO_550
CHEBI:26374
<ncicp:ComplexDefinition><ncicp:def-definition>A pterin compound which is wholly composed of a pteridine ring system, in which the pyrimidine ring has a carbonyl oxygen and an amino group.</ncicp:def-definition></ncicp:ComplexDefinition>
pterin
pterin
CHEBI:CHEBI_26375
NPO_693
CHEBI:26375
<ncicp:ComplexDefinition><ncicp:def-definition>A pteridine compound which is wholly or partly composed of a pteridine ring system in which the pyrimidine ring has a carbonyl oxygen and an amino group.</ncicp:def-definition></ncicp:ComplexDefinition>
pterin compound
pterin compound
CHEBI:CHEBI_26628
NPO_1100
CHEBI:26628
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of selenium.</ncicp:def-definition></ncicp:ComplexDefinition>
selenium molecular entity
selenium molecular entity
CHEBI:CHEBI_26677
NPO_1109
CHEBI:26677
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of silicon.</ncicp:def-definition></ncicp:ComplexDefinition>
silicon molecular entity
silicon molecular entity
CHEBI:CHEBI_26835
NPO_1101
CHEBI:26835
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of sulfur.</ncicp:def-definition></ncicp:ComplexDefinition>
sulfur molecular entity
sulfur molecular entity
CHEBI:CHEBI_26865
NPO_1137
CHEBI:26865
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of technetium.</ncicp:def-definition></ncicp:ComplexDefinition>
technetium molecular entity
technetium molecular entity
CHEBI:CHEBI_26873
NPO_381
CHEBI:26873
<ncicp:ComplexDefinition><ncicp:def-definition>Any natural product and related compound formally derived from isoprene units. They may contain oxygen in various functional groups. This class is subdivided according to the number of carbon atoms in the same manner as are terpenes. The skeleton of terpenoids may differ from strict additivity of isoprene units by the loss or shift of a fragment, generally a methyl group.</ncicp:def-definition></ncicp:ComplexDefinition>
terpenoid
terpenoid
CHEBI:CHEBI_26937
NPO_1065
CHEBI:26937
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic polycation which has ionic charge 4+.</ncicp:def-definition></ncicp:ComplexDefinition>
monoatomic tetracation
monoatomic tetracation
CHEBI:CHEBI_26986
NPO_913
CHEBI:26986
<ncicp:ComplexDefinition><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH(OH)-CH3)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
threonine
Thr
threonine
CHEBI:CHEBI_27008
NPO_1110
CHEBI:27008
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of tin.</ncicp:def-definition></ncicp:ComplexDefinition>
tin molecular entity
tin molecular entity
CHEBI:CHEBI_27153
NPO_1064
CHEBI:27153
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic polycation which has ionic charge 3+.</ncicp:def-definition></ncicp:ComplexDefinition>
monoatomic trication
monoatomic trication
CHEBI:CHEBI_27171
NPO_454
CHEBI:27171
<ncicp:ComplexDefinition><ncicp:def-definition>An organic heterocyclic compound, which has two rings.</ncicp:def-definition></ncicp:ComplexDefinition>
organic heterobicyclic compound
organic heterobicyclic compound
CHEBI:CHEBI_27266
NPO_964
CHEBI:27266
<ncicp:ComplexDefinition><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2(CH3)-CH3)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
valine
2-amino-3-methylbutanoic acid
Val
valine
CHEBI:CHEBI_27275
NPO_1144
CHEBI:27275
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of vanadium.</ncicp:def-definition></ncicp:ComplexDefinition>
vanadium molecular entity
vanadium molecular entity
CHEBI:CHEBI_27364
NPO_1123
CHEBI:27364
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of zinc.</ncicp:def-definition></ncicp:ComplexDefinition>
zinc molecular entity
zinc molecular entity
CHEBI:CHEBI_27470
NPO_422
CHEBI:27470
<ncicp:ComplexDefinition><ncicp:def-definition>A pterin compound which contains para-aminobenzoic acid and L-glutamate unit conjugated with the pterin structure.</ncicp:def-definition></ncicp:ComplexDefinition>
folic acid
folic acid
CHEBI:CHEBI_27570
NPO_329
CHEBI:27570
<ncicp:ComplexDefinition><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2c1c[nH]cn1)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
histidine
2-amino-3-(1H-imidazol-4-yl)propanoic acid
His
histidine
CHEBI:CHEBI_27601
NPO_289
CHEBI:27601
<ncicp:ComplexDefinition><ncicp:def-definition>A pteridine compound in which a pyrimidine ring is fused with a pyrazine ring. It has the structure c1cnc2ncncc2n1.</ncicp:def-definition></ncicp:ComplexDefinition>
pteridine
pteridine
CHEBI:CHEBI_27897
NPO_783
CHEBI:27897
<ncicp:ComplexDefinition><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(Cc1c[nH]c2ccccc12)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
tryptophan
Trp
tryptophan
CHEBI:CHEBI_27899
NPO_608
CHEBI:27899
<ncicp:ComplexDefinition><ncicp:def-definition>A platinum compound in which the platinum atom is complexed with two ammonia groups and two chlorine atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
cisplatin
anticancer drug that induces breakage of DNA helix
cisplatin
CHEBI:CHEBI_28044
NPO_139
CHEBI:28044
<ncicp:ComplexDefinition><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-c1ccccc1)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
phenylalanine
2-amino-3-phenylpropanoic acid
Phe
phenylalanine
CHEBI:CHEBI_28300
NPO_930
CHEBI:28300
<ncicp:ComplexDefinition><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2CH2C(NH2)=O)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
glutamine
2,5-diamino-5-oxopentanoic acid
glutamine
CHEBI:CHEBI_28358
NPO_1557
CHEBI:28358
<ncicp:ComplexDefinition><ncicp:def-definition>An organic compound which has the formula CH3CH(OH)C(OH)=O.</ncicp:def-definition></ncicp:ComplexDefinition>
lactic acid
2-hydroxypropanoic acid
alpha-hydroxypropanoic acid
lactic acid
CHEBI:CHEBI_28748
NPO_788
CHEBI:28748
<ncicp:ComplexDefinition><ncicp:def-definition>An anthracycline which is (1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-?-L-lyxo-hexopyranoside. It has a parent hydride, tetracene, and has substructures that classify it as a deoxy hexoside, and a quinone.</ncicp:def-definition></ncicp:ComplexDefinition>
doxorubicin
14-hydroxydaunorubicine
adriamycin
anticancer drug that inhibits protein activity related to DNA synthesis
doxorubicin
1
CHEBI:CHEBI_28830
NPO_346
CHEBI:28830
<ncicp:ComplexDefinition><ncicp:def-definition>A type of nitrogen mustard and an organochlorine compound.</ncicp:def-definition></ncicp:ComplexDefinition>
chlorambucil
anticancer drug that induces breakage of DNA helix
chlorambucil
CHEBI:CHEBI_29016
NPO_875
CHEBI:29016
<ncicp:ComplexDefinition><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-CH2-CH2-NH-C(NH2)=NH)-C(OH)=OH</ncicp:def-definition></ncicp:ComplexDefinition>
arginine
2-amino-5-(carbamimidamido)pentanoic acid
Arg
arginine
CHEBI:CHEBI_29033
NPO_1057
CHEBI:29033
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic dication of iron.</ncicp:def-definition></ncicp:ComplexDefinition>
iron (2+) ion
iron (2+) ion
CHEBI:CHEBI_29034
NPO_1069
CHEBI:29034
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic trication of iron.</ncicp:def-definition></ncicp:ComplexDefinition>
iron (3+) ion
iron (3+) ion
CHEBI:CHEBI_29105
NPO_1053
CHEBI:29105
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic dication of zinc.</ncicp:def-definition></ncicp:ComplexDefinition>
zinc (2+) ion
zinc (2+) ion
CHEBI:CHEBI_29256
NPO_465
CHEBI:29256
<ncicp:ComplexDefinition><ncicp:def-definition>A thiol is an organic compound which is characterized by the presence of a sulfhydryl group. It has the structure R-SH, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
thiol
mercaptan
sulfhydryl compound
thiol
CHEBI:CHEBI_29826
NPO_884
CHEBI:29826
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which has the structure -S-S-. The group is characteristic of an organic disulfide molecule wherein it is attached to organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
disulfanedyl group
disulfanedyl group
CHEBI:CHEBI_29917
NPO_910
CHEBI:29917
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which has the structure -SH. The group is characteristic of a thiol molecule wherein it is attached to an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
sulfhydryl group
thiol group
It is a substituent group from hydrogen sulfide.
sulfhydryl group
CHEBI:CHEBI_30105
NPO_462
CHEBI:30105
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which is a substituent group from diazene, and has the structure =[N+]=[N-]. The group is characteristic of a diazo compound wherein it is attached to an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
diazo group
diazo group
CHEBI:CHEBI_30412
NPO_1055
CHEBI:30412
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic cation which has ionic charge 2+.</ncicp:def-definition></ncicp:ComplexDefinition>
monoatomic dication
monoatomic dication
CHEBI:CHEBI_30417
NPO_1050
CHEBI:30417
<ncicp:ComplexDefinition><ncicp:def-definition>An anion of astatine.</ncicp:def-definition></ncicp:ComplexDefinition>
astatide
astatide
CHEBI:CHEBI_30511
NPO_1073
CHEBI:30511
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic pentacation of molybdenum.</ncicp:def-definition></ncicp:ComplexDefinition>
molybdenum (5+) ion
molybdenum (5+) ion
CHEBI:CHEBI_30563
NPO_1372
CHEBI:30563
<ncicp:ComplexDefinition><ncicp:def-definition>An oxide of silicon in which a silicon atom covalently bonded (double bond) with two oxygen atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
silicon dioxide
silica
silicon dioxide
CHEBI:CHEBI_30584
NPO_1070
CHEBI:30584
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic tetracation of silicon.</ncicp:def-definition></ncicp:ComplexDefinition>
silicon (4+) ion
silicon (4+) ion
CHEBI:CHEBI_30879
NPO_624
CHEBI:30879
<ncicp:ComplexDefinition><ncicp:def-definition>An alcohol is an organic hydroxy compound in which a hydroxyl group is attached to a saturated carbon atom. It has the general structure OH-C-([*])([*])[*].</ncicp:def-definition></ncicp:ComplexDefinition>
alcohol
alcohol
CHEBI:CHEBI_31355
NPO_603
CHEBI:31355
NCIT: C1282
<ncicp:ComplexDefinition><ncicp:def-definition>A platinum compound in which the platinum atom is complexed with two ammonia groups and a cyclobutane-dicarboxyl residue.</ncicp:def-definition></ncicp:ComplexDefinition>
carboplatin
anticancer drug that induces breakage of DNA helix
carboplatin
CHEBI:CHEBI_31941
NPO_749
CHEBI:31941
NCIT:C1181
<ncicp:ComplexDefinition><ncicp:def-definition>A platinum compound in which the platinum atom is complexed with 1,2-diaminocyclohexane (DACH) and with an oxalate bidentate ligand.</ncicp:def-definition></ncicp:ComplexDefinition>
oxaliplatin
anticancer drug that induces breakage of DNA helix
oxaliplatin
CHEBI:CHEBI_32863
NPO_805
CHEBI:32863
<ncicp:ComplexDefinition><ncicp:def-definition>A secondary amine is an amine which is formally derived from ammonia by replacing two hydrogen atoms by hydrocarbyl groups, and it is characterized by the presence of a secondary amine group. It has the structure R-NH-R', where R,R' denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
secondary amine
secondary amine
CHEBI:CHEBI_32876
NPO_832
CHEBI:32876
<ncicp:ComplexDefinition><ncicp:def-definition>A tertiary amine is an amine which is formally derived from ammonia by replacing three hydrogen atoms by hydrocarbyl groups, and it is characterized by the presence of a tertiary amine group. It has the structure R-N(-R")-R', where R,R' and R" denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
tertiary amine
tertiary amine
CHEBI:CHEBI_32877
NPO_947
CHEBI:32877
<ncicp:ComplexDefinition><ncicp:def-definition>A primary amine is an amine which is formally derived from ammonia by replacing one hydrogen atom by a hydrocarbyl group, and it is characterized by the presence of a primary amine group. It has the structure R-NH2, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
primary amine
primary amine
CHEBI:CHEBI_32952
NPO_143
CHEBI:32952
<ncicp:ComplexDefinition><ncicp:def-definition>An amine is an organic compound which is formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups, and it is thus characterized by the presence of a primary or secondary or tertiary amine groups. It has the structure R-NH2 or R-NH-R' or R-N(-R")-R', where R, R' and R" denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
amine
amine
CHEBI:CHEBI_32988
NPO_769
CHEBI:32988
<ncicp:ComplexDefinition><ncicp:def-definition>An amide is an organic compound formally derived from an oxoacid by replacing an acidic hydroxyl group of the oxoacid by an amino or substituted amino group. It is characterized by the presence of an "amide group."</ncicp:def-definition></ncicp:ComplexDefinition>
amide
amide
CHEBI:CHEBI_33003
NPO_1072
CHEBI:33003
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic pentacation of vanadium.</ncicp:def-definition></ncicp:ComplexDefinition>
vanadium 5(+) ion
vanadium 5(+) ion
CHEBI:CHEBI_33238
NPO_1026
CHEBI:33238
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which consists of a single atom.</ncicp:def-definition></ncicp:ComplexDefinition>
monoatomic entity
monoatomic entity
CHEBI:CHEBI_33240
NPO_1139
CHEBI:33240
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A compound which consists of a central atom (usually metallic) to which is attached a surrounding array of other groups of atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
coordination compound
coordination compound
CHEBI:CHEBI_33244
NPO_202
CHEBI:33244
<ncicp:ComplexDefinition><ncicp:def-definition>An organic compound or molecule which is characterized by the presence of a functional group.</ncicp:def-definition></ncicp:ComplexDefinition>
organic functional class
organic functional class
CHEBI:CHEBI_33246
NPO_1567
CHEBI:33246
<ncicp:ComplexDefinition><ncicp:def-definition>Any substituent group which does not contain carbon.</ncicp:def-definition></ncicp:ComplexDefinition>
inorganic group
inorganic group
CHEBI:CHEBI_33248
NPO_559
CHEBI:33248
<ncicp:ComplexDefinition><ncicp:def-definition>A hydrocarbyl group is a univalent substituent group formed by removing a hydrogen atom from a hydrocarbon.</ncicp:def-definition></ncicp:ComplexDefinition>
hydrocarbyl group
hydrocarbyl group
CHEBI:CHEBI_33259
NPO_1025
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A polyatomic entity which consists of a single element.</ncicp:def-definition></ncicp:ComplexDefinition>
homoatomic molecular entity
homoatomic molecular entity
CHEBI:CHEBI_33273
NPO_1038
CHEBI:33273
<ncicp:ComplexDefinition><ncicp:def-definition>An anion which consists of more than one atom.</ncicp:def-definition></ncicp:ComplexDefinition>
polyatomic anion
polyatomic anion
CHEBI:CHEBI_33285
NPO_293
CHEBI:33285
<ncicp:ComplexDefinition><ncicp:def-definition>A heteroorganic compound is an organic compound in which carbon atoms or organic groups are bonded directly to one or more heteroatoms.</ncicp:def-definition></ncicp:ComplexDefinition>
heteroorganic compound
heteroorganic entity
heteroorganic molecule
heteroorganic compound
CHEBI:CHEBI_33296
NPO_1081
CHEBI:33296
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of an alkali metal.</ncicp:def-definition></ncicp:ComplexDefinition>
alkali metal molecular entity
alkali metal molecular entity
CHEBI:CHEBI_33299
NPO_1080
CHEBI:33299
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of an alkaline earth metal.</ncicp:def-definition></ncicp:ComplexDefinition>
alkaline earth molecular entity
alkaline earth molecular entity
CHEBI:CHEBI_33302
NPO_1085
CHEBI:33302
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of a Group-15 element.</ncicp:def-definition></ncicp:ComplexDefinition>
pnictogen molecular entity
pnictogen molecular entity
CHEBI:CHEBI_33304
NPO_1086
CHEBI:33304
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of a Group-16 element.</ncicp:def-definition></ncicp:ComplexDefinition>
chalogen molecular entity
chalogen molecular entity
CHEBI:CHEBI_33305
NPO_1102
CHEBI:33305
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of tellurium.</ncicp:def-definition></ncicp:ComplexDefinition>
tellurium molecular entity
tellurium molecular entity
CHEBI:CHEBI_33308
NPO_790
CHEBI:33308
<ncicp:ComplexDefinition><ncicp:def-definition>A carboxylic ester is an organic compound which is characterized by the presence of an carboxylic ester group. It has the structure R-C(=O)-O-R', where R,R' denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
carboxylic ester
carboxylic ester
CHEBI:CHEBI_33327
NPO_1371
CHEBI:33327
<ncicp:ComplexDefinition><ncicp:def-definition>An oxide of silicon.</ncicp:def-definition></ncicp:ComplexDefinition>
silicon oxide
silicon oxide
CHEBI:CHEBI_33338
NPO_826
CHEBI:33338
<ncicp:ComplexDefinition><ncicp:def-definition>A hydrocarbyl group which is derived from an arene by removal of a hydrogen atom from a ring carbon atom.</ncicp:def-definition></ncicp:ComplexDefinition>
aryl group
aryl group
CHEBI:CHEBI_33422
NPO_1066
CHEBI:33422
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic polycation which has ionic charge 5+.</ncicp:def-definition></ncicp:ComplexDefinition>
monoatomic pentacation
monoatomic pentacation
CHEBI:CHEBI_33423
NPO_1067
CHEBI:33423
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic polycation which has ionic charge 6+.</ncicp:def-definition></ncicp:ComplexDefinition>
monoatomic hexacation
monoatomic hexacation
CHEBI:CHEBI_33429
NPO_1043
CHEBI:33429
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic anion which has ionic charge 1-.</ncicp:def-definition></ncicp:ComplexDefinition>
monoatomic monoanion
monoatomic monoanion
CHEBI:CHEBI_33496
NPO_1051
CHEBI:33496
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic monanion of rubidide.</ncicp:def-definition></ncicp:ComplexDefinition>
rubidide
rubidide
CHEBI:CHEBI_33504
NPO_1076
CHEBI:33504
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic cation of alkali metal.</ncicp:def-definition></ncicp:ComplexDefinition>
alkali metal cation
alkali metal cation
CHEBI:CHEBI_33513
NPO_1077
CHEBI:33513
<ncicp:ComplexDefinition><ncicp:def-definition>A monatomic cation of an alkaline earth metal.</ncicp:def-definition></ncicp:ComplexDefinition>
alkaline earth metal cation
alkaline earth metal cation
CHEBI:CHEBI_33575
NPO_574
CHEBI:33575
<ncicp:ComplexDefinition><ncicp:def-definition>A carboxylic acid is an organic acid compound which is characterized by the presence of a carboxyl group. It has the structure R-C(=O)-OH, where R denotes an organic group or a hydrogen atom.</ncicp:def-definition></ncicp:ComplexDefinition>
carboxylic acid
carboxyl compound
prefix: Carboxy-
suffix: -oic acid
carboxylic acid
CHEBI:CHEBI_33581
NPO_1087
CHEBI:33581
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of a Group-13 element.</ncicp:def-definition></ncicp:ComplexDefinition>
boron group molecular entity
boron group molecular entity
CHEBI:CHEBI_33582
NPO_1088
CHEBI:33582
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of a Group-14 element.</ncicp:def-definition></ncicp:ComplexDefinition>
carbon group molecular entity
carbon group molecular entity
CHEBI:CHEBI_33583
NPO_1079
CHEBI:33583
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of a noble gas.</ncicp:def-definition></ncicp:ComplexDefinition>
noble gas molecular entity
noble gas compound
noble gas molecular entity
CHEBI:CHEBI_33584
NPO_1111
CHEBI:33584
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of germanium.</ncicp:def-definition></ncicp:ComplexDefinition>
germanium molecular entity
germanium molecular entity
CHEBI:CHEBI_33585
NPO_1112
CHEBI:33585
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of lead.</ncicp:def-definition></ncicp:ComplexDefinition>
lead molecular entity
lead molecular entity
CHEBI:CHEBI_33620
NPO_1105
CHEBI:33620
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of aluminum.</ncicp:def-definition></ncicp:ComplexDefinition>
aluminum molecular entity
aluminum molecular entity
CHEBI:CHEBI_33673
NPO_1114
CHEBI:33673
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of a zinc group (Group-12) element.</ncicp:def-definition></ncicp:ComplexDefinition>
zinc group molecular entity
zinc group molecular entity
CHEBI:CHEBI_33674
NPO_1082
CHEBI:33674
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of a s-block element.</ncicp:def-definition></ncicp:ComplexDefinition>
s-block molecular entity
s-block molecular entity
CHEBI:CHEBI_33675
NPO_1078
CHEBI:33675
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of a p-block element.</ncicp:def-definition></ncicp:ComplexDefinition>
p-block molecular entity
p-block molecular entity
CHEBI:CHEBI_33676
NPO_1083
CHEBI:33676
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of a d-block element.</ncicp:def-definition></ncicp:ComplexDefinition>
d-block molecular entity
d-block molecular entity
CHEBI:CHEBI_33692
NPO_1148
CHEBI:33692
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A compound of hydrogen with other chemical elements.</ncicp:def-definition></ncicp:ComplexDefinition>
hydride
hydride
CHEBI:CHEBI_33693
NPO_1560
CHEBI:33693
<ncicp:ComplexDefinition><ncicp:def-definition>A hydride containing one or more oxygen atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
oxygen hydride
oxygen hydride
CHEBI:CHEBI_33694
NPO_882
CHEBI:33694
MESH: D001704
<ncicp:ComplexDefinition><ncicp:def-definition>A polymer formed by living organisms.</ncicp:def-definition></ncicp:ComplexDefinition>
biopolymer
biomacromolecule
biopolymer
CHEBI:CHEBI_33696
NPO_1001
CHEBI:33696
<ncicp:ComplexDefinition><ncicp:def-definition>A polynucleotide which is present in living cells.</ncicp:def-definition></ncicp:ComplexDefinition>
nucleic acid
nucleic acid
CHEBI:CHEBI_33697
NPO_1003
CHEBI:33697
<ncicp:ComplexDefinition><ncicp:def-definition>A nucleic acid which is a derivative of DNA having ribose in place of deoxyribose, and uracil in place of thymine.</ncicp:def-definition></ncicp:ComplexDefinition>
ribonucleic acid
RNA
ribonucleic acid
CHEBI:CHEBI_33702
NPO_1040
CHEBI:33702
<ncicp:ComplexDefinition><ncicp:def-definition>A cation which consists of more than one atom.</ncicp:def-definition></ncicp:ComplexDefinition>
polyatomic cation
polyatomic cation
CHEBI:CHEBI_33704
NPO_632
CHEBI:33704
<ncicp:ComplexDefinition><ncicp:def-definition>An aminoacid in which a primary amine group and a carboxyl group are attached to the same carbon atom, which is called the alpha?carbon..</ncicp:def-definition></ncicp:ComplexDefinition>
alpha-aminoacid
alpha-aminoacid
CHEBI:CHEBI_33709
NPO_506
CHEBI:33709
<ncicp:ComplexDefinition><ncicp:def-definition>A carboxylic acid containing one or more amine groups.</ncicp:def-definition></ncicp:ComplexDefinition>
aminoacid
aminoacid
CHEBI:CHEBI_33741
NPO_1115
CHEBI:33741
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of a chromium group (Group-6) element.</ncicp:def-definition></ncicp:ComplexDefinition>
chromium group molecular entity
chromium group molecular entity
CHEBI:CHEBI_33742
NPO_1128
CHEBI:33742
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of tungsten.</ncicp:def-definition></ncicp:ComplexDefinition>
tungsten molecular entity
tungsten molecular entity
CHEBI:CHEBI_33743
NPO_1116
CHEBI:33743
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of a manganese group (Group-7) element.</ncicp:def-definition></ncicp:ComplexDefinition>
manganese group molecular entity
manganese group molecular entity
CHEBI:CHEBI_33744
NPO_1117
CHEBI:33744
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of a iron group (Group-8) element.</ncicp:def-definition></ncicp:ComplexDefinition>
iron group molecular entity
iron group molecular entity
CHEBI:CHEBI_33745
NPO_1118
CHEBI:33745
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of a copper group (Group-11) element.</ncicp:def-definition></ncicp:ComplexDefinition>
copper group molecular entity
copper group molecular entity
CHEBI:CHEBI_33746
NPO_1119
CHEBI:33746
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of a vanadium group (Group-5) element.</ncicp:def-definition></ncicp:ComplexDefinition>
vanadium group molecular entity
vanadium group molecular entity
CHEBI:CHEBI_33747
NPO_1120
CHEBI:33747
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of a nickel group (Group-10) element.</ncicp:def-definition></ncicp:ComplexDefinition>
nickel group molecular entity
nickel group molecular entity
CHEBI:CHEBI_33748
NPO_1138
CHEBI:33748
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of nickel.</ncicp:def-definition></ncicp:ComplexDefinition>
nickel molecular entity
nickel molecular entity
CHEBI:CHEBI_33749
NPO_1140
CHEBI:33749
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of platinum.</ncicp:def-definition></ncicp:ComplexDefinition>
platinum molecular entity
platinum molecular entity
CHEBI:CHEBI_33767
NPO_1121
CHEBI:33767
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of a cobalt group (Group-9) element.</ncicp:def-definition></ncicp:ComplexDefinition>
cobalt group molecular entity
cobalt group molecular entity
CHEBI:CHEBI_33768
NPO_1122
CHEBI:33768
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of a titanium group (Group-4) element.</ncicp:def-definition></ncicp:ComplexDefinition>
titanium group molecular entity
titanium group molecular entity
CHEBI:CHEBI_33822
NPO_201
CHEBI:33822
<ncicp:ComplexDefinition><ncicp:def-definition>An organic compound which is characterized by the presence of one or more hydroxyl groups attached to carbon atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
organic hydroxy compound
hydroxy compound
organic hydroxy compound
CHEBI:CHEBI_33839
NPO_364
CHEBI:33839
MESH:D011108
<ncicp:ComplexDefinition><ncicp:def-definition>A polymer is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.</ncicp:def-definition></ncicp:ComplexDefinition>
polymer
macromolecule
polymer molecule
[definition source]: CHEBI
polymer
CHEBI:CHEBI_33862
NPO_297
CHEBI:33862
<ncicp:ComplexDefinition><ncicp:def-definition>A coordination compound which contains platinum as the central atom.</ncicp:def-definition></ncicp:ComplexDefinition>
platinum coordination compound
platinum coordination compound
CHEBI:CHEBI_33887
NPO_1129
CHEBI:33887
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of rhodium.</ncicp:def-definition></ncicp:ComplexDefinition>
rhodium molecular entity
rhodium molecular entity
CHEBI:CHEBI_33888
NPO_1130
CHEBI:33888
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of cobalt.</ncicp:def-definition></ncicp:ComplexDefinition>
cobalt molecular entity
cobalt molecular entity
CHEBI:CHEBI_33964
NPO_1133
CHEBI:33964
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of silver.</ncicp:def-definition></ncicp:ComplexDefinition>
silver molecular entity
silver molecular entity
CHEBI:CHEBI_33969
NPO_1132
CHEBI:33969
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of gold.</ncicp:def-definition></ncicp:ComplexDefinition>
gold molecular entity
gold molecular entity
CHEBI:CHEBI_35352
NPO_503
CHEBI:35352
<ncicp:ComplexDefinition><ncicp:def-definition>An organonitrogen compound is a heteroorganic compound containing at least one carbon-nitrogen bond.</ncicp:def-definition></ncicp:ComplexDefinition>
organonitrogen compound
organonitrogen compound
CHEBI:CHEBI_35358
NPO_908
CHEBI:35358
<ncicp:ComplexDefinition><ncicp:def-definition>A sulfonamide is an amide derived from sulfonic acids, and thus characterized by the presence of a sulfonamide group. It has the structure R-S(=O)-NH2, R-S(=O)-NH-R' or R-S(=O)-N(-R")-R', where R,R',R" denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
sulfonamide
sulfonamide
CHEBI:CHEBI_35359
NPO_232
CHEBI:35359
<ncicp:ComplexDefinition><ncicp:def-definition>An amidine is an organic compound which is a derivative of a carboxylic acid, in which the hydroxy group is replaced by an amino group and the oxo group is replaced by =NR, and therefore, it has the structure R'-C(=N-R)-NH2, where R' denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
carboxamidine
carboxamidine
CHEBI:CHEBI_35362
NPO_583
CHEBI:35362
<ncicp:ComplexDefinition><ncicp:def-definition>A hydrazide is an organic compound or molecule which is derived from an oxoacid RkE(=O)l(OH)m (l ? 0) by replacing ?OH by ?N(-R)-N(-R')-R" (R,R',R" groups commonly denote H).</ncicp:def-definition></ncicp:ComplexDefinition>
hydrazide
hydrazide
CHEBI:CHEBI_35363
NPO_629
CHEBI:35363
<ncicp:ComplexDefinition><ncicp:def-definition>A carbohydrazide is a hyrazide derived from a carboxylic acid, and therefore has the structure R""-(C=O)-N(-R)-N(-R')-R", where R"" denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
carbohydrazide
carbohydrazide
CHEBI:CHEBI_35489
NPO_573
CHEBI:35489
<ncicp:ComplexDefinition><ncicp:def-definition>An organic disulfide is an organic compound which is characterized by the presence of a disulfanedyl group / disulfide bond. It has the structure R-S-S-R', where R,R' denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
organic disulfide
organic disulfide
CHEBI:CHEBI_35610
NPO_777
CHEBI:35610
NCIT: C274
<ncicp:ComplexDefinition><ncicp:def-definition>Anticancer drug, which brings about a cancer therapeutic effect by inhibiting or preventing the proliferation of neoplasms; i.e., it inhibits the maturation ,growth or spread of tumor cells.</ncicp:def-definition></ncicp:ComplexDefinition>
antineoplastic agent
antineoplastic drug
antineoplastic agent
CHEBI:CHEBI_35734
NPO_1135
CHEBI:35734
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of ruthenium.</ncicp:def-definition></ncicp:ComplexDefinition>
ruthenium molecular entity
ruthenium molecular entity
CHEBI:CHEBI_36080
NPO_982
CHEBI:36080
<ncicp:ComplexDefinition><ncicp:def-definition>A biopolymer which is genetically encoded, the structure of which essentially consists of long chains of amino acid residues (derived from alpha aminoacids) connected by peptide bonds and have distinct and varied three-dimensional structures, usually containing alpha helices and beta sheets as well as looping and folded chains.</ncicp:def-definition></ncicp:ComplexDefinition>
protein
protein
CHEBI:CHEBI_36141
NPO_774
CHEBI:36141
<ncicp:ComplexDefinition><ncicp:def-definition>Cyclic ketone having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of ?CH= groups into ?C(=O)? groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included).</ncicp:def-definition></ncicp:ComplexDefinition>
quinone
quinone
CHEBI:CHEBI_36357
NPO_1023
CHEBI:36357
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which consists of more than one atom.</ncicp:def-definition></ncicp:ComplexDefinition>
polyatomic entity
polyatomic entity
CHEBI:CHEBI_36358
NPO_1033
CHEBI:36358
<ncicp:ComplexDefinition><ncicp:def-definition>An ion which consists of more than one atom.</ncicp:def-definition></ncicp:ComplexDefinition>
polyatomic ion
polyatomic ion
CHEBI:CHEBI_36586
NPO_527
CHEBI:36586
<ncicp:ComplexDefinition><ncicp:def-definition>A carbonyl compound is an organic compound which is characterized by the presence of a carbonyl group, and therefore, has the structure R-(C=O)-R', where R, R" are organic groups or hydrogen atom.</ncicp:def-definition></ncicp:ComplexDefinition>
carbonyl compound
carbonyl compound
CHEBI:CHEBI_36606
NPO_883
CHEBI:36606
<ncicp:ComplexDefinition><ncicp:def-definition>An acid anhydride is an organic compound which is characterized by the presence of an acid anhydride group. It has the structure R-C(=O)-O-C(=O)-R', where R, R' stand for organic groups or hydrogen atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
acid anhydride
acid anhydride
CHEBI:CHEBI_36683
NPO_194
CHEBI:36683
<ncicp:ComplexDefinition><ncicp:def-definition>An organochlorine compound is a compound containing at least one carbon-chlorine bond.</ncicp:def-definition></ncicp:ComplexDefinition>
organochlorine compound
organochlorine compound
CHEBI:CHEBI_36914
NPO_1032
CHEBI:36914
<ncicp:ComplexDefinition><ncicp:def-definition>An ion which is inorganic.</ncicp:def-definition></ncicp:ComplexDefinition>
inorganic ion
inorganic ion
CHEBI:CHEBI_36915
NPO_1042
CHEBI:36915
<ncicp:ComplexDefinition><ncicp:def-definition>A cation which is inorganic.</ncicp:def-definition></ncicp:ComplexDefinition>
inorganic cation
inorganic cation
CHEBI:CHEBI_36916
NPO_1029
CHEBI:36916
<ncicp:ComplexDefinition><ncicp:def-definition>An ion which is positively charged.</ncicp:def-definition></ncicp:ComplexDefinition>
cation
cation
CHEBI:CHEBI_36917
NPO_1103
CHEBI:36917
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of polonium.</ncicp:def-definition></ncicp:ComplexDefinition>
polonium molecular entity
polonium molecular entity
CHEBI:CHEBI_36919
NPO_1096
CHEBI:36919
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of antimony.</ncicp:def-definition></ncicp:ComplexDefinition>
antimony molecular entity
antimony molecular entity
CHEBI:CHEBI_37110
NPO_1106
CHEBI:37110
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of thallum.</ncicp:def-definition></ncicp:ComplexDefinition>
thallium molecular entity
thallium molecular entity
CHEBI:CHEBI_37111
NPO_1107
CHEBI:37111
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of gallium.</ncicp:def-definition></ncicp:ComplexDefinition>
gallium molecular entity
gallium molecular entity
CHEBI:CHEBI_37112
NPO_1108
CHEBI:37112
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of indium.</ncicp:def-definition></ncicp:ComplexDefinition>
indium molecular entity
indium molecular entity
CHEBI:CHEBI_37138
NPO_1093
CHEBI:37138
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of astatine.</ncicp:def-definition></ncicp:ComplexDefinition>
astatine molecular entity
astatine molecular entity
CHEBI:CHEBI_37143
NPO_698
CHEBI:37143
<ncicp:ComplexDefinition><ncicp:def-definition>An organofluorine compound is a compound containing at least one carbon-fluorine bond.</ncicp:def-definition></ncicp:ComplexDefinition>
organofluorine compound
organofluorine compound
CHEBI:CHEBI_37163
NPO_676
CHEBI:37163
MESH:D005936
<ncicp:ComplexDefinition><ncicp:def-definition>A homopolysaccharide which is composed of glucose residues.</ncicp:def-definition></ncicp:ComplexDefinition>
glucan
glucan
CHEBI:CHEBI_37164
NPO_896
CHEBI:37164
<ncicp:ComplexDefinition><ncicp:def-definition>A polysaccharide, which is composed of a single type of monosaccharide residue. They are named by replacing the ending '-ose' of the sugar by '-an'.</ncicp:def-definition></ncicp:ComplexDefinition>
homopolysaccharide
homoglycan
[definition source]: CHEBI
homopolysaccharide
CHEBI:CHEBI_37196
NPO_1098
CHEBI:37196
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of bismuth.</ncicp:def-definition></ncicp:ComplexDefinition>
bismuth molecular entity
bismuth molecular entity
CHEBI:CHEBI_37217
NPO_1142
CHEBI:37217
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of titanium.</ncicp:def-definition></ncicp:ComplexDefinition>
titanium molecular entity
titanium molecular entity
CHEBI:CHEBI_37218
NPO_1143
CHEBI:37218
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of zirconium.</ncicp:def-definition></ncicp:ComplexDefinition>
zirconium molecular entity
zirconium molecular entity
CHEBI:CHEBI_37230
NPO_1141
CHEBI:37230
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of palladium.</ncicp:def-definition></ncicp:ComplexDefinition>
palladium molecular entity
palladium molecular entity
CHEBI:CHEBI_37286
NPO_1060
CHEBI:37286
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic dication of gadolinium.</ncicp:def-definition></ncicp:ComplexDefinition>
gadolinium (2+) ion
gadolinium (2+) ion
CHEBI:CHEBI_37294
NPO_1071
CHEBI:37294
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic tetracation of gadolinium.</ncicp:def-definition></ncicp:ComplexDefinition>
gadolinium (4+) ion
gadolinium (4+) ion
CHEBI:CHEBI_37334
NPO_681
CHEBI:37334
NCIT:C1966
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A compound or molecule which is used to enhance image formation of biological structures and functions for the detection and diagnosis of disease.</ncicp:def-definition></ncicp:ComplexDefinition>
diagnostic imaging agent
image enhancement agent
diagnostic imaging agent
CHEBI:CHEBI_37335
NPO_581
CHEBI:37335
<ncicp:ComplexDefinition><ncicp:def-definition>A contrast agent, which has magnetic properties and provides contrast in images captured using MRI.</ncicp:def-definition></ncicp:ComplexDefinition>
MRI contrast agent
contrast agent in magnetic resonance imaging
MRI contrast agent
CHEBI:CHEBI_37336
NPO_361
CHEBI:37336
<ncicp:ComplexDefinition><ncicp:def-definition>A contrast agent, which provides contrast in images captured using radioactive imaging techniques.</ncicp:def-definition></ncicp:ComplexDefinition>
radioactive imaging agent
radioactive imaging agent
CHEBI:CHEBI_37337
NPO_250
CHEBI:37337
<ncicp:ComplexDefinition><ncicp:def-definition>A contrast agent, which provides contrast in images captured using ultrasound imaging techniques.</ncicp:def-definition></ncicp:ComplexDefinition>
ultrasound contrast agent
contrast agent in ultrasound imaging
ultrasound imaging contrast agent
ultrasound contrast agent
CHEBI:CHEBI_37577
NPO_1024
CHEBI:37577
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A polyatomic entity which consists of two or more chemical elements.</ncicp:def-definition></ncicp:ComplexDefinition>
heteroatomic molecular entity
heteroatomic molecular entity
CHEBI:CHEBI_37598
NPO_172
CHEBI:37598
<ncicp:ComplexDefinition><ncicp:def-definition>A type of organonitrogen compound, which has two ?-haloalkyl groups bound to a nitrogen atom, as in (X?C2H2?C2H2)2NR.</ncicp:def-definition></ncicp:ComplexDefinition>
nitrogen mustard
nitrogen mustard
CHEBI:CHEBI_37622
NPO_269
CHEBI:37622
<ncicp:ComplexDefinition><ncicp:def-definition>A carboxamide is an amide derived from carboxylic acids. It is characterized by the presence of a carboxamide group. It has the structure R-C(=O)-NH2, R-C(=O)-NH-R' or R-C(=O)-N(-R")-R', where R,R',R" stands for organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
carboxamide
carboxamide
CHEBI:CHEBI_37699
NPO_436
CHEBI:37699
NCIT: C1404
<ncicp:ComplexDefinition><ncicp:def-definition>An enzyme inhibitor, which inhibits the activity of protein kinase.</ncicp:def-definition></ncicp:ComplexDefinition>
protein kinase inhibitor
inhibits phosphorylation in the signaling pathway, which regulates a variety of fundamental processes, such as cell growth, mitogenesis, metabolism, gene transcription, cell cycle control, and the immune response.
protein kinase inhibitor
CHEBI:CHEBI_37926
NPO_134
CHEBI:37926
<ncicp:ComplexDefinition><ncicp:def-definition>An organic compound which is derived from fluorescein by replacing a hydrogen atom of the benzene ring (the one that does not contain the hydroxyl groups), with an amine-reactive isothiocyanate group.</ncicp:def-definition></ncicp:ComplexDefinition>
fluorescein isothiocyanate
FITC
fluorescein isothiocyanate
CHEBI:CHEBI_38530
NPO_386
CHEBI:38530
<ncicp:ComplexDefinition><ncicp:def-definition>A quinazoline compound is a derivative of quinazoline.</ncicp:def-definition></ncicp:ComplexDefinition>
quinazoline compound
quinazoline compound
CHEBI:CHEBI_38532
NPO_971
CHEBI:38532
<ncicp:ComplexDefinition><ncicp:def-definition>A hydrazone is an organic compound which is formally derived from aldehydes or ketones by replacing =O by =N-NH2 or =N-NH-R', and thus, characterized by a "hydrazone group." It has the structure R-C(=N-NH2)-R" or R-C(=N-NH-R')-R".</ncicp:def-definition></ncicp:ComplexDefinition>
hydrazone
hydrazone
CHEBI:CHEBI_38560
NPO_578
CHEBI:38560
<ncicp:ComplexDefinition><ncicp:def-definition>A protein that contains a non-protein prosthetic group such as sugar, nucleic acid, lipid, or metal ion.</ncicp:def-definition></ncicp:ComplexDefinition>
conjugated protein
[definition source]: L. G. Wade Jr. Organic Chemistry 3rd Edition
conjugated protein
CHEBI:CHEBI_39444
NPO_569
CHEBI:39444
<ncicp:ComplexDefinition><ncicp:def-definition>A diazo compound is an organic compound which is characterized by the presence of a diazo group. It has the structure R=[N+]=[N-], where R denotes an organic group..</ncicp:def-definition></ncicp:ComplexDefinition>
diazo compound
diazo compound
CHEBI:CHEBI_3992
NPO_373
CHEBI:3992
<ncicp:ComplexDefinition><ncicp:def-definition>A ketone which is a cyclic compound containing one or more ketone groups.</ncicp:def-definition></ncicp:ComplexDefinition>
cyclic ketone
cyclic ketone
CHEBI:CHEBI_4027
NPO_890
CHEBI:4027
<ncicp:ComplexDefinition><ncicp:def-definition>A type of nitrogen mustard.</ncicp:def-definition></ncicp:ComplexDefinition>
cyclophosphamide
anticancer drug that induces breakage of DNA helix
cyclophosphamide
CHEBI:CHEBI_41774
NPO_254
CHEBI:41774
<ncicp:ComplexDefinition><ncicp:def-definition>Tamoxifen is an organic compound, which has a parent hydride, stilbin; and which blocks the effects of the hormone estrogen in the body. It is used to prevent or delay the return of breast cancer or to control its spread.</ncicp:def-definition></ncicp:ComplexDefinition>
tamoxifen
modifies expression of specific genes
tamoxifen
CHEBI:CHEBI_42068
NPO_817
CHEBI:42068
<ncicp:ComplexDefinition><ncicp:def-definition>An anthracycline which is (1S,3S)-3-acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-?-L-lyxo-hexopyranoside.</ncicp:def-definition></ncicp:ComplexDefinition>
idarubicin
4-Demethoxydaunorubicin
anticancer drug that inhibits protein activity related to DNA synthesis
idarubicin
CHEBI:CHEBI_42485
NPO_590
CHEBI:42485
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which has the structure -C(=O)H. The group is characteristic of an aldehyde wherein it is attached to the remaining part of the molecule via covalent bond with hydrogen or carbon atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
aldehyde group
formyl group
aldehyde group
CHEBI:CHEBI_43176
NPO_941
CHEBI:43176
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group, in which an oxygen atom is bonded to a hydrogen atom, and has the structure -OH. The group is characteristic of an organic hydroxy molecule wherein it is attached to a carbon atom via a single covalent bond.</ncicp:def-definition></ncicp:ComplexDefinition>
hydroxyl group
hydroxy group
prefix: hydroxy
suffix: -ol
hydroxyl group
CHEBI:CHEBI_44185
NPO_741
CHEBI:44185
NCIT:C642
<ncicp:ComplexDefinition><ncicp:def-definition>A pteridine compound has a pteridine substructure; which has functional parent, L-glutamic acid; which has other substructures that classify it a monocarboxylic acid amide and a dicarboxylic acid.</ncicp:def-definition></ncicp:ComplexDefinition>
methotrexate
An antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities. Methotrexate binds to and inhibits the enzyme dihydrofolate reductase, resulting in inhibition of purine nucleotide and thymidylate synthesis and, subsequently, inhibition of DNA and RNA syntheses. Methotrexate also exhibits potent immunosuppressant activity although the mechanism(s) of actions is unclear.
methotrexate
CHEBI:CHEBI_45863
NPO_860
CHEBI:45863
MESH: D017239
NCIT:C1411
<ncicp:ComplexDefinition><ncicp:def-definition>A diterpenoid, which consists of a tetracyclic core called baccatin III, and an amide tail.</ncicp:def-definition></ncicp:ComplexDefinition>
paclitaxel
Paclitaxel is isolated from the bark of the Pacific yew tree.
paclitaxel
CHEBI:CHEBI_46345
NPO_365
CHEBI:46345
<ncicp:ComplexDefinition><ncicp:def-definition>An organofluorine compound, which has uracil as the funcitonal parent.</ncicp:def-definition></ncicp:ComplexDefinition>
5-fluorouracil
anticancer drug that inhibits protein activity related to DNA synthesis
5-fluorouracil
CHEBI:CHEBI_46662
NPO_1563
CHEBI:46662
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A mineral is a naturally occurring chemical substance formed through geological processes that has a characteristic chemical composition, a highly ordered atomic structure and specific physical properties.</ncicp:def-definition></ncicp:ComplexDefinition>
mineral
mineral
CHEBI:CHEBI_46723
NPO_1564
CHEBI:46723
<ncicp:ComplexDefinition><ncicp:def-definition>A mineral which contains phosphate anions.</ncicp:def-definition></ncicp:ComplexDefinition>
phosphate mineral
phosphate mineral
CHEBI:CHEBI_46787
NPO_1831
CHEBI:46787
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A liquid which can dissolve other substancees (solutes) without any change in their chemical composition.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>CHEBI</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
solvent
solvent
CHEBI:CHEBI_46793
NPO_444
CHEBI:46793
<ncicp:ComplexDefinition><ncicp:def-definition>A polymer made by the polymerization of ethylene oxide.</ncicp:def-definition></ncicp:ComplexDefinition>
poly(ethylene glycol)
PEG
poly(ethylene glycol)
CHEBI:CHEBI_46883
NPO_838
CHEBI:46883
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which has the structure -C(=O)-OH. The group is characteristic of carboxylic acid compounds, wherein it is attached to a hydrogen atom or a carbon atom by a single covalent bond.</ncicp:def-definition></ncicp:ComplexDefinition>
carboxyl group
carboxyl group
CHEBI:CHEBI_47854
NPO_135
CHEBI:47854
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which has the structure -X, where 'X' denotes a halogen atom.</ncicp:def-definition></ncicp:ComplexDefinition>
halo group
halo group
CHEBI:CHEBI_48077
NPO_215
CHEBI:48077
<ncicp:ComplexDefinition><ncicp:def-definition>A functional group which has the structure -C(=O)-CH=CH2, and the group is characteristic of acryloyl compounds.</ncicp:def-definition></ncicp:ComplexDefinition>
acryloyl group
acryloyl group
CHEBI:CHEBI_48120
NPO_539
CHEBI:48120
<ncicp:ComplexDefinition><ncicp:def-definition>A polyketide which has a tetrahydronaphthacenedione ring structure attached by a glycosidic linkage to the amino sugar daunosamine.</ncicp:def-definition></ncicp:ComplexDefinition>
anthracycline
anthracycline
CHEBI:CHEBI_48422
NPO_595
CHEBI:48422
MESH: D020533
NCIT: C1742
<ncicp:ComplexDefinition><ncicp:def-definition>An antineoplastic agent that slows down or prevents the formation and growth of blood or lymphatic vessels. In cancer therapy, angiogenesis inhibitors target blood vessels that supply tumors, thereby inhibiting tumor growth.</ncicp:def-definition></ncicp:ComplexDefinition>
angiogenesis inhibitor
angiogenesis antagonist
angiogenesis inhibitor
CHEBI:CHEBI_48819
NPO_588
CHEBI:48819
<ncicp:ComplexDefinition><ncicp:def-definition>A cyano group is a substituent group from hydrogen cyanide, and has the structure -C#N.</ncicp:def-definition></ncicp:ComplexDefinition>
cyano group
cyano group
CHEBI:CHEBI_48828
NPO_1059
CHEBI:48828
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic dication of cobalt.</ncicp:def-definition></ncicp:ComplexDefinition>
cobalt (2+) ion
cobalt (2+) ion
CHEBI:CHEBI_4911
NPO_168
CHEBI:4911
<ncicp:ComplexDefinition><ncicp:def-definition>An organic compound or molecule, which has a functional parent, podophyllotoxin; which has substructure that classifies it as a beta-D-glucoside.</ncicp:def-definition></ncicp:ComplexDefinition>
etoposide
(5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-?-D-glucopyranoside
etoposide
CHEBI:CHEBI_49446
NPO_1074
CHEBI:49446
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic hexacation of molybdenum.</ncicp:def-definition></ncicp:ComplexDefinition>
molybdenum (6+) ion
molybdenum (6+) ion
CHEBI:CHEBI_49468
NPO_1062
CHEBI:49468
<ncicp:ComplexDefinition><ncicp:def-definition>A monatomic monocation of silver.</ncicp:def-definition></ncicp:ComplexDefinition>
silver (1+) ion
silver (1+) ion
CHEBI:CHEBI_49482
NPO_1061
CHEBI:49482
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic monocation of gold.</ncicp:def-definition></ncicp:ComplexDefinition>
gold (1+) ion
gold (1+) ion
CHEBI:CHEBI_49588
NPO_1058
CHEBI:49588
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic dication of europium.</ncicp:def-definition></ncicp:ComplexDefinition>
europium (2+) ion
europium (2+) ion
CHEBI:CHEBI_49618
NPO_1068
CHEBI:49618
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic trication of gadolinium.</ncicp:def-definition></ncicp:ComplexDefinition>
gadolinium (3+) ion
gadolinium (3+) ion
CHEBI:CHEBI_49668
NPO_123
CHEBI:49668
<ncicp:ComplexDefinition><ncicp:def-definition>A type of quinazoline compound.</ncicp:def-definition></ncicp:ComplexDefinition>
gefitinib
Iressa
ZD-1839
drug directed against intracellular domain of membrane receptor
removed 'has_role some epidermal growth factor receptor tyrosine kinase inhibitor'
gefitinib
CHEBI:CHEBI_49955
NPO_1075
CHEBI:49955
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic hexacation of tungsten.</ncicp:def-definition></ncicp:ComplexDefinition>
tungsten (6+) ion
tungsten (6+) ion
CHEBI:CHEBI_50086
NPO_1044
CHEBI:50086
<ncicp:ComplexDefinition><ncicp:def-definition>A monoatomic anion which has ionic charge -4.</ncicp:def-definition></ncicp:ComplexDefinition>
monoatomic tetraanion
monoatomic tetraanion
CHEBI:CHEBI_50819
NPO_1149
CHEBI:50819
<ncicp:ComplexDefinition><ncicp:def-definition>An iron oxide with the chemical formula Fe2O3.</ncicp:def-definition></ncicp:ComplexDefinition>
iron (III) oxide
ferric oxide
iron (III) oxide
CHEBI:CHEBI_50820
NPO_1150
CHEBI:50820
<ncicp:ComplexDefinition><ncicp:def-definition>An iron oxide with the chemical formula FeO.</ncicp:def-definition></ncicp:ComplexDefinition>
iron (II) oxide
ferrous oxide
iron (II) oxide
CHEBI:CHEBI_50821
NPO_1151
CHEBI:50821
<ncicp:ComplexDefinition><ncicp:def-definition>An iron oxide with the chemical formula Fe3O4.</ncicp:def-definition></ncicp:ComplexDefinition>
iron (II,III) oxide
ferrosoferric oxide
iron (II,III) oxide
CHEBI:CHEBI_51143
NPO_1097
CHEBI:51143
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity which contains one or more atoms of nitrogen.</ncicp:def-definition></ncicp:ComplexDefinition>
nitrogen molecular entity
nitrogen molecular entity
CHEBI:CHEBI_52254
NPO_1565
CHEBI:52254
<ncicp:ComplexDefinition><ncicp:def-definition>A phosphate mineral with the general formula Ca5(PO4)3X where X = OH, F or Cl.</ncicp:def-definition></ncicp:ComplexDefinition>
apatite
apatite
CHEBI:CHEBI_52255
NPO_1566
CHEBI:52255
<ncicp:ComplexDefinition><ncicp:def-definition>A phosphate mineral with the formula Ca5(PO4)3(OH).</ncicp:def-definition></ncicp:ComplexDefinition>
hydroxyapatite
hydroxylapatite
hydroxyapatite
FIX:FIX_0000015
NPO_1473
FIX:0000015
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An absorption spectroscopic technique in which a beam of infrared light is used to irradiate a sample. The IR absorption spectra obtained with this technique, is used to identify compounds or investigate sample composition based on the correlation of absorption bands in the spectrum of the unknown compound with known absorption frequencies for specific types of bonds.</ncicp:def-definition><ncicp:Definition_Review_Date>100611</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
infrared spectroscopy
IR spectroscopy
The technique is based on the fact that molecules have specific frequencies at which they rotate or vibrate corresponding to discrete energy levels (vibrational modes).
infrared spectroscopy
FIX:FIX_0000016
NPO_1475
FIX:0000016
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An absorption spectroscopic technique in which the irradiating light has wavelengths within the ultraviolet and visible regions of the electromagnetic spectrum.</ncicp:def-definition><ncicp:Definition_Review_Date>100614</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
ultraviolet/visible spectroscopy
UV-Vis spectroscopy
ultraviolet/visible spectroscopy
FIX:FIX_0000041
NPO_1471
FIX:0000041
NCIT:C78871
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectroscopic technique which is carried out in vaccum, and is used to estimate the elemental composition and chemical state of the elements on the surface of a material by irradiating the material surface with a beam of soft monochromatic (magnesium/aluminum) X-rays and measuring the kinetic energy of photoelectrons emitted from the core orbitals of the surface elements within a few nm from the material surface.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
x-ray photoelectron spectroscopy
ESCA
Electron Spectroscopy for Chemical Analysis
XPS
Photoelectrons are collected and analyzed by the XPS instrument to produce a spectrum of emission intensity versus electron binding energy. Since each element has a unique set of binding energies, XPS can be used to identify the elements on the surface. Also, peak areas at nominal binding energies can be used to quantify concentration of the elements. Small shifts in these binding energies (chemical shifts) provide powerful information about sample chemical states and short-range chemistry .
[definition: based on NCIT, http://encyclopedia.thefreedictionary.com, http://www.chem.umd.edu/facility/xps.php]
x-ray photoelectron spectroscopy
FIX:FIX_0000053
NPO_1458
FIX:0000053
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A separation technique for separation of mixtures, in which a mixture dissolved in a mobile liquid or gas medium, is passed through a stationary adsorbing medium to separate the components based on differential affinities of the components for the mobile medium and for the stationary medium.</ncicp:def-definition><ncicp:Definition_Review_Date>100616</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
chromatography
[definition adapted from NCIT, WordNet, http://encyclopedia.thefreedictionary.com/chromatography]
chromatography
FIX:FIX_0000058
NPO_1472
FIX:0000058
NCIT:C17157
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectroscopic technique which is based on the detection of inelastically scattered monochromatic light from a laser in the visible, near infrared, or near ultraviolet range, by a substance (or sample under investigation). A laser beam of a given wavelength is used to irradiate a spot on the sample under investigation. The inelastically scattered light ( photons scattered at lower frequencies or higher wavelengths compared to that of the incident photons (Raman effect)), contains information about the energies of molecular vibrations and rotations, and these depend on the particular atoms or ions that comprise the molecule, the chemical bonds connect them, the symmetry of their molecule structure, and the physico-chemical environment where they reside.</ncicp:def-definition><ncicp:Definition_Review_Date>100527</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
Raman spectroscopy
[definition: adapted from http://epsc.wustl.edu/haskin-group/Raman/faqs.htm, http://encyclopedia.thefreedictionary.com]
Raman spectroscopy
FIX:FIX_0000098
NPO_1460
FIX:0000098
<ncicp:ComplexDefinition><ncicp:def-definition>A chromatography technique in which the mobile phase is a gas.</ncicp:def-definition></ncicp:ComplexDefinition>
gas chromatography
gas chromatography
FIX:FIX_0000116
NPO_1448
FIX:0000116
<ncicp:ComplexDefinition><ncicp:def-definition>An atomic force microscopy technique in which the tip of the cantilever is in contact with the sample's surface. In the contact mode, the overall force between the tip and the surface is repulsive and it is kept constant during scanning by maintaining a constant deflection, and therefore constant height above the surface.</ncicp:def-definition></ncicp:ComplexDefinition>
contact atomic force microscopy
contact AFM
[definition: adapted from http://en.wikipedia.org, http://www.nanoscience.com/education/AFM.html]
contact atomic force microscopy
FIX:FIX_0000117
NPO_1449
FIX:0000117
<ncicp:ComplexDefinition><ncicp:def-definition>An atomic force microscopy technique in which the tip of the cantilever is not in contact with sample's surface. In non contact mode, the overall force between the tip and the surface is attractive. The cantilever is oscillated at a frequency slightly above its resonance frequency where the amplitude of oscillation is typically a few nanometers (<10 nm). The van der Waals forces, which are strongest from 1 nm to 10 nm above the surface, or any other long range force which extends above the surface acts to decrease the resonance frequency of the cantilever. This decrease in resonance frequency combined with the feedback loop system maintains a constant oscillation amplitude or frequency by adjusting the average tip-to-sample distance. Measuring the tip-to-sample distance at each (x,y) data point allows the scanning software to construct a topographic image of the sample surface.</ncicp:def-definition></ncicp:ComplexDefinition>
non contact atomic force micrsocopy
NC-AFM
non contact atomic force micrsocopy
FIX:FIX_0000118
NPO_1450
FIX:0000118
<ncicp:ComplexDefinition><ncicp:def-definition>A non contact atomic force microscopy technique based on the use of magnetic force microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
magnetic force microscopy
magnetic force microscopy
FIX:FIX_0000321
NPO_1474
FIX:0000321
<ncicp:ComplexDefinition><ncicp:def-definition>An infrared spectroscopy where the beam of light that irradiates the sample has wavelengths within the near-infrared region of the electromagnetic spectrum.</ncicp:def-definition></ncicp:ComplexDefinition>
near-infrared spectroscopy
NIR spectroscopy
near-infrared spectroscopy
FIX:FIX_0000402
NPO_1466
FIX:0000402
NCIT:C62323
<ncicp:ComplexDefinition><ncicp:def-definition>A technique based on the disperson of light or electromagnetic radiation into a range of directions by virtue of its interaction with a material medium through which it passes.</ncicp:def-definition></ncicp:ComplexDefinition>
light scattering
light scattering technique
[definition: adapted from NCIT]
light scattering
FIX:FIX_0000607
NPO_1459
FIX:0000607
<ncicp:ComplexDefinition><ncicp:def-definition>A chromatography technique classified based on the phase of the mobile medium.</ncicp:def-definition></ncicp:ComplexDefinition>
chromatography by mobile phase state
chromatography by physical state of the mobile phase
chromatography by mobile phase state
FIX:FIX_0000608
NPO_1461
FIX:0000608
<ncicp:ComplexDefinition><ncicp:def-definition>A chromatography technique in which the mobile phase is a liquid.</ncicp:def-definition></ncicp:ComplexDefinition>
liquid chromatography
LC
liquid chromatography
FIX:FIX_0000610
NPO_1463
FIX:0000610
<ncicp:ComplexDefinition><ncicp:def-definition>A chromatography technique classified based on the mechanism of separation.</ncicp:def-definition></ncicp:ComplexDefinition>
chromatography by separation mechanism
chromatography by separation mechanism
FIX:FIX_0000626
NPO_1464
FIX:0000626
NCIT:C16433
<ncicp:ComplexDefinition><ncicp:def-definition>A chromatography technique which uses porous gels to separate solute molecules or particles based on size.</ncicp:def-definition></ncicp:ComplexDefinition>
size-exclusion chromatography
GPC
SEC
gel filtration chromatography
gel permeation chromatography
size-exclusion chromatography
FIX:FIX_0000630
NPO_1462
FIX:0000630
NCIT: C16434
<ncicp:ComplexDefinition><ncicp:def-definition>A liquid chromatography technique in which the sample is forced by a liquid (mobile phase) at high pressure, through a column that is packed with a solid stationary phase.</ncicp:def-definition></ncicp:ComplexDefinition>
high pressure liquid chromatography
HPLC
high performance liquid chromatography
high pressure liquid chromatography
FIX:FIX_0000836
NPO_1457
FIX:0000836
NCIT:C17637
<ncicp:ComplexDefinition><ncicp:def-definition>An electrophoresis technique, in which a sample is introduced into a capillary tube and the components are separated by the application of high voltage. Due to the large surface to volume ratio, cooling is more efficient, allowing use of higher voltages. As a result, separation occurs more quickly and sensitivity is increased. The technique allows for separation of proteins, nucleic acids, and carbohydrates.</ncicp:def-definition></ncicp:ComplexDefinition>
capillary electrophoresis
capillary electrophoresis
GO:GO_0001525
NPO_657
GO:0001525
<ncicp:ComplexDefinition><ncicp:def-definition>Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.</ncicp:def-definition></ncicp:ComplexDefinition>
angiogenesis
blood vessel formation from pre-existing blood vessels
angiogenesis
GO:GO_0003674
NPO_362
GO:0003674
<ncicp:ComplexDefinition><ncicp:def-definition>Elemental activity, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.</ncicp:def-definition></ncicp:ComplexDefinition>
molecular function
molecular activity
[source]: GO
molecular function
GO:GO_0003676
NPO_1620
GO:0003676
<ncicp:ComplexDefinition><ncicp:def-definition>Interacting selectively and non-covalently with any nucleic acid.</ncicp:def-definition></ncicp:ComplexDefinition>
nucleic acid binding
nucleic acid binding
GO:GO_0003677
NPO_1621
GO:0003677
<ncicp:ComplexDefinition><ncicp:def-definition>Any molecular function by which a gene product interacts selectively with DNA (deoxyribonucleic acid).</ncicp:def-definition></ncicp:ComplexDefinition>
DNA binding
microtubule/chromatin interaction
plasmid binding
DNA binding
GO:GO_0003823
NPO_959
GO:0003823
<ncicp:ComplexDefinition><ncicp:def-definition>Interacting selectively with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.</ncicp:def-definition></ncicp:ComplexDefinition>
antigen binding
antigen binding
GO:GO_0003824
NPO_584
GO:0003824
<ncicp:ComplexDefinition><ncicp:def-definition>Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. [source: ISBN:0198506732]</ncicp:def-definition></ncicp:ComplexDefinition>
enzyme activity
catalytic activity
enzyme activity
GO:GO_0003916
NPO_700
GO:0003916
<ncicp:ComplexDefinition><ncicp:def-definition>Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA.</ncicp:def-definition></ncicp:ComplexDefinition>
DNA topoisomerase activity
DNA topoisomerase activity
GO:GO_0003918
NPO_450
GO:0003918
<ncicp:ComplexDefinition><ncicp:def-definition>Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.</ncicp:def-definition></ncicp:ComplexDefinition>
DNA topoisomerase type II activity
DNA topoisomerase (ATP-hydrolyzing) activity
DNA topoisomerase type II activity
GO:GO_0004146
NPO_593
GO:0004146
<ncicp:ComplexDefinition><ncicp:def-definition>Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+.</ncicp:def-definition></ncicp:ComplexDefinition>
dihydrofolate reductase activity
dihydrofolate reductase activity
GO:GO_0004672
NPO_953
GO:0004672
<ncicp:ComplexDefinition><ncicp:def-definition>Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. [source: MetaCyc:PROTEIN-KINASE-RXN]</ncicp:def-definition></ncicp:ComplexDefinition>
protein kinase activity
protein kinase activity
GO:GO_0004713
NPO_217
GO:0004713
<ncicp:ComplexDefinition><ncicp:def-definition>Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. [source: EC:2.7.10]</ncicp:def-definition></ncicp:ComplexDefinition>
protein tyrosine kinase activity
protein tyrosine kinase activity
GO:GO_0004799
NPO_820
GO:0004799
<ncicp:ComplexDefinition><ncicp:def-definition>Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP. [source: EC:2.1.1.45]</ncicp:def-definition></ncicp:ComplexDefinition>
thymidylate synthase activity
5,10-methylenetetrahydrofolate:dUMP C-methyltransferase activity
TMP synthetase activity
dTMP synthase activity
methylenetetrahydrofolate:dUMP C-methyltransferase activity
thymidylate synthetase activity
thymidylate synthase activity
GO:GO_0004872
NPO_1593
GO:0004872
<ncicp:ComplexDefinition><ncicp:def-definition>Combining with an extracellular or intracellular messenger to initiate a change in cell activity.</ncicp:def-definition></ncicp:ComplexDefinition>
receptor activity
receptor activity
GO:GO_0005102
NPO_780
GO:0005102
<ncicp:ComplexDefinition><ncicp:def-definition>Interacting selectively with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. [source: GOC:bf, GOC:ceb, ISBN:0198506732]</ncicp:def-definition></ncicp:ComplexDefinition>
receptor binding
receptor binding
GO:GO_0005154
NPO_165
GO:0005154
<ncicp:ComplexDefinition><ncicp:def-definition>Interacting selectively with the epidermal growth factor receptor. [source: GOC:ai]</ncicp:def-definition></ncicp:ComplexDefinition>
epidermal growth factor receptor binding
EGF receptor binding
EGFR binding
TGF-alpha receptor binding
transforming growth factor alpha receptor binding
epidermal growth factor receptor binding
GO:GO_0005488
NPO_547
GO:0005488
<ncicp:ComplexDefinition><ncicp:def-definition>The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
binding
binding
GO:GO_0005515
NPO_170
GO:0005515
<ncicp:ComplexDefinition><ncicp:def-definition>Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). [source: GOC:go_curators]</ncicp:def-definition></ncicp:ComplexDefinition>
protein binding
protein amino acid binding
protein binding
GO:GO_0005575
NPO_1008
GO:0005575
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material entity, which is the part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.</ncicp:def-definition><ncicp:attr>Gene Ontology (GO)</ncicp:attr></ncicp:ComplexDefinition>
cellular component
cellular component
GO:GO_0005615
NPO_1580
FMA:70022
GO:0005615
<ncicp:ComplexDefinition><ncicp:def-definition>That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. [source: GO]</ncicp:def-definition></ncicp:ComplexDefinition>
extracellular space
intercellular space
extracellular space
GO:GO_0005623
NPO_1009
GO:0005623
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material entity which is the basic structural and functional unit of all organisms. It includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.</ncicp:def-definition></ncicp:ComplexDefinition>
cell
cell
GO:GO_0006259
NPO_1014
GO:0006259
<ncicp:ComplexDefinition><ncicp:def-definition>The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. [source: ISBN:0198506732]</ncicp:def-definition></ncicp:ComplexDefinition>
DNA metabolic process
DNA metabolism
DNA metabolic process
GO:GO_0006260
NPO_142
GO:0006260
<ncicp:ComplexDefinition><ncicp:def-definition>A process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA.</ncicp:def-definition></ncicp:ComplexDefinition>
DNA replication
DNA biosynthesis
DNA synthesis
DNA replication
GO:GO_0006304
NPO_1624
GO_0006304
<ncicp:ComplexDefinition><ncicp:def-definition>The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties.</ncicp:def-definition></ncicp:ComplexDefinition>
DNA modification
DNA modification
GO:GO_0006305
NPO_1625
GO:0006305
<ncicp:ComplexDefinition><ncicp:def-definition>The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also modify the bases of incoming nucleotides in the course of DNA synthesis.</ncicp:def-definition></ncicp:ComplexDefinition>
DNA alkylation
DNA alkylation
GO:GO_0006350
NPO_1015
GO:0006350
<ncicp:ComplexDefinition><ncicp:def-definition>The synthesis of either RNA on a template of DNA or DNA on a template of RNA. [source: ISBN:0198506732]</ncicp:def-definition></ncicp:ComplexDefinition>
transcription
transcription
GO:GO_0006351
NPO_840
GO:0006351
<ncicp:ComplexDefinition><ncicp:def-definition>The synthesis of RNA on a template of DNA.</ncicp:def-definition></ncicp:ComplexDefinition>
DNA-dependent transcription
DNA-dependent transcription
GO:GO_0006355
NPO_1650
GO:0006355
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that modulates the frequency, rate or extent of DNA-dependent transcription.</ncicp:def-definition></ncicp:ComplexDefinition>
regulation of DNA-dependent transcription
regulation of DNA-dependent transcription
GO:GO_0006897
NPO_299
GO:0006897
NCIT: C16544
<ncicp:ComplexDefinition><ncicp:def-definition>Cellular uptake of extracellular materials within membrane-limited vacuoles or microvesicles.</ncicp:def-definition></ncicp:ComplexDefinition>
endocytosis
[definition source]: NCI_Thesaurus
endocytosis
GO:GO_0006909
NPO_1368
GO:0006909
<ncicp:ComplexDefinition><ncicp:def-definition>The process whereby phagocytes engulf external particulate material. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.</ncicp:def-definition></ncicp:ComplexDefinition>
phagocytosis
phagocytosis
GO:GO_0006915
NPO_548
GO:0006915
<ncicp:ComplexDefinition><ncicp:def-definition>A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle the cell and result in cell death. Apoptosis begins internally with condensation and subsequent fragmentation of the cell nucleus (blebbing) while the plasma membrane remains intact. Other characteristics of apoptosis include DNA fragmentation and the exposure of phosphatidyl serine on the cell surface. [source: GOC:go_curators, ISBN:0198506732]</ncicp:def-definition></ncicp:ComplexDefinition>
apoptosis
apoptotic programmed cell death
programmed cell death by apoptosis
apoptosis
GO:GO_0007067
NPO_712
GO:0007067
<ncicp:ComplexDefinition><ncicp:def-definition>Progression through mitosis, the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother. [source: GOC:ma, ISBN:0198547684]</ncicp:def-definition></ncicp:ComplexDefinition>
mitosis
mitosis
GO:GO_0007155
NPO_997
GO:0007155
<ncicp:ComplexDefinition><ncicp:def-definition>The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. [source: GOC:hb, GOC:pf]</ncicp:def-definition></ncicp:ComplexDefinition>
cell adhesion
cell adhesion
GO:GO_0007162
NPO_1635
GO:0007162
NCIT:C40708
<ncicp:ComplexDefinition><ncicp:def-definition>A process that stops, prevents or reduces the frequency, rate or extent of cell adhesion.</ncicp:def-definition></ncicp:ComplexDefinition>
negative regulation of cell adhesion
cell adhesion inhibition
down regulation of cell adhesion
down-regulation of cell adhesion
downregulation of cell adhesion
inhibition of cell adhesion
An inhibition which involves interference with, or restraint of, the activities of biologic molecules, biologic complexes, or subcellular components that promote the adherence of cells to surfaces or to other cells. [NCIT definition]
negative regulation of cell adhesion
GO:GO_0008092
NPO_984
GO:0008092
<ncicp:ComplexDefinition><ncicp:def-definition>Interacting selectively with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton. [source: GOC:mah]</ncicp:def-definition></ncicp:ComplexDefinition>
cytoskeletal protein binding
cytoskeletal protein binding
GO:GO_0008150
NPO_427
GO:0008150
<ncicp:ComplexDefinition><ncicp:def-definition>Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.</ncicp:def-definition></ncicp:ComplexDefinition>
biological process
physiological process
[source]: GO
biological process
GO:GO_0008152
NPO_1004
GO:0008152
<ncicp:ComplexDefinition><ncicp:def-definition>The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. [source: GOC:go_curators, ISBN:0198547684]</ncicp:def-definition></ncicp:ComplexDefinition>
metabolic process
metabolism
metabolic process
GO:GO_0008156
NPO_1636
GO:0008156
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication.</ncicp:def-definition></ncicp:ComplexDefinition>
negative regulation of DNA replication
down regulation of DNA replication
down-regulation of DNA replication
downregulation of DNA replication
inhibition of DNA replication
negative regulation of DNA replication
GO:GO_0008219
NPO_995
GO:0008219
<ncicp:ComplexDefinition><ncicp:def-definition>The specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. [source: GOC:ems]</ncicp:def-definition></ncicp:ComplexDefinition>
cell death
cell death
GO:GO_0009058
NPO_1005
GO:0009058
<ncicp:ComplexDefinition><ncicp:def-definition>The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. [source: GOC:curators, ISBN:0198547684]</ncicp:def-definition></ncicp:ComplexDefinition>
biosynthetic process
anabolism
biosynthesis
biosynthetic process
GO:GO_0009987
NPO_994
GO:0009987
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [source: GOC:go_curators, GOC:isa_complete]</ncicp:def-definition></ncicp:ComplexDefinition>
cellular process
cellular physiological process
cellular process
GO:GO_0012501
NPO_996
GO:0012501
<ncicp:ComplexDefinition><ncicp:def-definition>Cell death resulting from activation of endogenous cellular processes. [source: GOC:lr]</ncicp:def-definition></ncicp:ComplexDefinition>
programmed cell death
programmed cell death
GO:GO_0015631
NPO_814
GO:0015631
<ncicp:ComplexDefinition><ncicp:def-definition>Interacting selectively with monomeric or multimeric forms of tubulin, including microtubules. [source: GOC:clt]</ncicp:def-definition></ncicp:ComplexDefinition>
tubulin binding
tubulin binding
GO:GO_0016070
NPO_1016
GO:0016070
<ncicp:ComplexDefinition><ncicp:def-definition>The chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. [source: ISBN:0198506732]</ncicp:def-definition></ncicp:ComplexDefinition>
RNA metabolic process
RNA metabolism
RNA metabolic process
GO:GO_0016337
NPO_479
GO:0016337
<ncicp:ComplexDefinition><ncicp:def-definition>The attachment of one cell to another cell via adhesion molecules. [source: GOC:hb]</ncicp:def-definition></ncicp:ComplexDefinition>
cell-cell adhesion
cell-cell adhesion
GO:GO_0016525
NPO_1646
GO:0016525
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that stops, prevents or reduces the frequency, rate or extent of angiogenesis.</ncicp:def-definition></ncicp:ComplexDefinition>
negative regulation of angiogenesis
angiogenesis inhibition
down regulation of angiogenesis
down-regulation of angiogenesis
downregulation of angiogenesis
inhibition of angiogenesis
negative regulation of angiogenesis
GO:GO_0022402
NPO_998
GO:0022402
<ncicp:ComplexDefinition><ncicp:def-definition>A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. [source: GOC:isa_complete]</ncicp:def-definition></ncicp:ComplexDefinition>
cell cycle process
cell cycle process
GO:GO_0022403
NPO_999
GO:0022403
<ncicp:ComplexDefinition><ncicp:def-definition>A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events. [source: GOC:isa_complete]</ncicp:def-definition></ncicp:ComplexDefinition>
cell cycle phase
cell cycle phase
GO:GO_0030331
NPO_575
GO:0030331
<ncicp:ComplexDefinition><ncicp:def-definition>Interacting selectively with an estrogen receptor.</ncicp:def-definition></ncicp:ComplexDefinition>
estrogen receptor binding
estrogen receptor binding
GO:GO_0032502
NPO_992
GO:0032502
<ncicp:ComplexDefinition><ncicp:def-definition>A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. [source: GOC:isa_complete]</ncicp:def-definition></ncicp:ComplexDefinition>
developmental process
developmental process
GO:GO_0032774
NPO_1017
GO:0032774
<ncicp:ComplexDefinition><ncicp:def-definition>The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. [source: GOC:mah]</ncicp:def-definition></ncicp:ComplexDefinition>
RNA biosynthetic process
RNA anabolism
RNA biosynthesis
RNA formation
RNA synthesis
RNA biosynthetic process
GO:GO_0034960
NPO_1012
GO:0034960
<ncicp:ComplexDefinition><ncicp:def-definition>The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells. [source: GOC:mah]</ncicp:def-definition></ncicp:ComplexDefinition>
cellular biopolymer metabolic process
cellular biopolymer metabolism
cellular biopolymer metabolic process
GO:GO_0034961
NPO_1007
GO:0034961
<ncicp:ComplexDefinition><ncicp:def-definition>The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells. [source: GOC:mah]</ncicp:def-definition></ncicp:ComplexDefinition>
cellular biopolymer biosynthetic process
cellular biopolymer biosynthesis
cellular biopolymer biosynthetic process
GO:GO_0035257
NPO_798
GO:0035257
<ncicp:ComplexDefinition><ncicp:def-definition>Interacting selectively with a nuclear hormone receptor, a ligand-dependent receptor found in the nucleus of the cell. [source: GOC:bf]</ncicp:def-definition></ncicp:ComplexDefinition>
nuclear hormone receptor binding
nuclear hormone receptor binding
GO:GO_0035258
NPO_958
GO:0035258
<ncicp:ComplexDefinition><ncicp:def-definition>Interacting selectively with a steroid hormone receptor. [source: GOC:bf]</ncicp:def-definition></ncicp:ComplexDefinition>
steroid hormone receptor binding
steroid hormone receptor binding
GO:GO_0042533
NPO_647
GO:0042533
<ncicp:ComplexDefinition><ncicp:def-definition>The chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis. [source: GOC:jl, PMID:10891884]</ncicp:def-definition></ncicp:ComplexDefinition>
tumor necrosis factor biosynthetic process
TNF alpha biosynthesis
tumor necrosis factor alpha biosynthesis
tumor necrosis factor anabolism
tumor necrosis factor biosynthesis
tumor necrosis factor synthesis
tumor necrosis factor biosynthetic process
GO:GO_0042536
NPO_1662
GO:0042536
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis.</ncicp:def-definition></ncicp:ComplexDefinition>
inhibition of tumor necrosis factor biosynthetic process
inhibition of tumor necrosis factor biosynthetic process
GO:GO_0043014
NPO_600
GO:0043014
<ncicp:ComplexDefinition><ncicp:def-definition>Interacting selectively with the microtubule constituent protein alpha-tubulin. [source: GOC:jl]</ncicp:def-definition></ncicp:ComplexDefinition>
alpha-tubulin binding
alpha-tubulin binding
GO:GO_0043015
NPO_512
GO:0043015
<ncicp:ComplexDefinition><ncicp:def-definition>Interacting selectively with the microtubule constituent protein gamma-tubulin. [source: GOC:jl]</ncicp:def-definition></ncicp:ComplexDefinition>
gamma-tubulin binding
gamma-tubulin binding
GO:GO_0043085
NPO_1655
GO:0043085
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that activates or increases the activity of an enzyme.</ncicp:def-definition></ncicp:ComplexDefinition>
positive regulation of enzyme activity
activation of enzyme activity
stimulation of enzyme activity
up regulation of enzyme activity
up-regulation of enzyme activity
upregulation of enzyme activity
positive regulation of enzyme activity
GO:GO_0043086
NPO_1632
GO:0043086
REX:0000233
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that stops or reduces the activity of an enzyme.</ncicp:def-definition></ncicp:ComplexDefinition>
enzyme inhibition
down regulation of enzyme activity
inhibition of enzyme activity
enzyme inhibition
GO:GO_0043283
NPO_1013
GO:0043283
<ncicp:ComplexDefinition><ncicp:def-definition>The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins. [source: GOC:jl, http://en.wikipedia.org/]</ncicp:def-definition></ncicp:ComplexDefinition>
biopolymer metabolic process
biopolymer metabolism
biopolymer metabolic process
GO:GO_0043284
NPO_1006
GO:0043284
<ncicp:ComplexDefinition><ncicp:def-definition>The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature e.g. polysaccharides and proteins. [source: GOC:jl, http://en.wikipedia.org/]</ncicp:def-definition></ncicp:ComplexDefinition>
biopolymer biosynthetic process
biopolymer biosynthesis
biopolymer formation
biopolymer synthesis
biopolymer biosynthetic process
GO:GO_0044092
NPO_1654
GO:0044092
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.</ncicp:def-definition></ncicp:ComplexDefinition>
negative regulation of molecular function
negative regulation of molecular function
GO:GO_0044093
NPO_1644
GO:0044093
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.</ncicp:def-definition></ncicp:ComplexDefinition>
positive regulation of molecular function
positive regulation of molecular function
GO:GO_0044237
NPO_1011
GO:0044237
<ncicp:ComplexDefinition><ncicp:def-definition>The chemical reactions and pathways by which individual cells transform chemical substances. [source: GOC:go_curators]</ncicp:def-definition></ncicp:ComplexDefinition>
cellular metabolic process
cellular metabolism
cellular metabolic process
GO:GO_0044249
NPO_1010
GO:0044249
<ncicp:ComplexDefinition><ncicp:def-definition>The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. [source: GOC:jl]</ncicp:def-definition></ncicp:ComplexDefinition>
cellular biosynthetic process
cellular biosynthetic process
GO:GO_0045740
NPO_1648
GO:0045740
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that activates or increases the frequency, rate or extent of DNA replication.</ncicp:def-definition></ncicp:ComplexDefinition>
positive regulation of DNA replication
activation of DNA replication
stimulation of DNA replication
up regulation of DNA replication
up-regulation of DNA replication
upregulation of DNA replication
positive regulation of DNA replication
GO:GO_0045766
NPO_1645
GO:0045766
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that activates or increases angiogenesis.</ncicp:def-definition></ncicp:ComplexDefinition>
positive regulation of angiogenesis
positive regulation of angiogenesis
GO:GO_0045785
NPO_1643
GO:0045785
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that activates or increases the frequency, rate or extent of cell adhesion.</ncicp:def-definition></ncicp:ComplexDefinition>
positive regulation of cell adhesion
positive regulation of cell adhesion
GO:GO_0045839
NPO_1640
GO:0045839
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.</ncicp:def-definition></ncicp:ComplexDefinition>
negative regulation of mitosis
down regulation of mitosis
down-regulation of mitosis
downregulation of mitosis
inhibition of mitosis
negative regulation of mitosis
GO:GO_0045840
NPO_1639
GO:0045840
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that activates or increases the frequency, rate or extent of mitosis.</ncicp:def-definition></ncicp:ComplexDefinition>
positive regulation of mitosis
activation of mitosis
stimulation of mitosis
up regulation of mitosis
up-regulation of mitosis
upregulation of mitosis
positive regulation of mitosis
GO:GO_0045892
NPO_1652
GO:0045892
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that stops, prevents or reduces the frequency, rate or extent of DNA-dependent transcription.</ncicp:def-definition></ncicp:ComplexDefinition>
negative regulation of DNA-dependent transcription
down regulation of DNA-dependent transcription
down-regulation of DNA-dependent transcription
downregulation of DNA-dependent transcription
inhibition of DNA-dependent transcription
negative regulation of DNA-dependent transcription
GO:GO_0045893
NPO_1651
GO:0045893
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that activates or increases the frequency, rate or extent of DNA-dependent transcription.</ncicp:def-definition></ncicp:ComplexDefinition>
positive regulation of DNA-dependent transcription
activation of DNA-dependent transcription
stimulation of DNA-dependent transcription
up regulation of DNA-dependent transcription
up-regulation of DNA-dependent transcription
upregulation of DNA-dependent transcription
positive regulation of DNA-dependent transcription
GO:GO_0046655
NPO_1629
GO:0046655
<ncicp:ComplexDefinition><ncicp:def-definition>The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.</ncicp:def-definition></ncicp:ComplexDefinition>
folic acid metabolic process
folate metabolic process
folate metabolism
folic acid metabolism
folic acid metabolic process
GO:GO_0048487
NPO_793
GO:0048487
<ncicp:ComplexDefinition><ncicp:def-definition>Interacting selectively with the microtubule constituent protein beta-tubulin. [source: GOC:krc]</ncicp:def-definition></ncicp:ComplexDefinition>
beta-tubulin binding
beta-tubulin binding
GO:GO_0048518
NPO_1638
GO:0048518
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that activates or increases the frequency, rate or extent of biological process.</ncicp:def-definition></ncicp:ComplexDefinition>
positive regulation of biological process
positive regulation of biological process
GO:GO_0048519
NPO_1647
GO:0048519
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that stops, prevents or reduces the frequency, rate or extent of a biological process.</ncicp:def-definition></ncicp:ComplexDefinition>
negative regulation of biological process
negative regulation of biological process
GO:GO_0048646
NPO_993
GO:0048646
<ncicp:ComplexDefinition><ncicp:def-definition>The process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. [source: GOC:dph, GOC:jic]</ncicp:def-definition></ncicp:ComplexDefinition>
anatomical structure formation
formation of an anatomical structure
anatomical structure formation
GO:GO_0050789
NPO_1637
GO:0050789
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
regulation of biological process
regulation of physiological process
regulation of biological process
GO:GO_0051301
NPO_545
GO:0051301
<ncicp:ComplexDefinition><ncicp:def-definition>The process resulting in the physical partitioning and separation of a cell into daughter cells. [source: GOC:go_curators]</ncicp:def-definition></ncicp:ComplexDefinition>
cell division
cell division
GO:GO_0051427
NPO_499
GO:0051427
<ncicp:ComplexDefinition><ncicp:def-definition>Interacting selectively with a receptor for hormones. [source: GOC:ai]</ncicp:def-definition></ncicp:ComplexDefinition>
hormone receptor binding
hormone receptor binding
GO:GO_0065009
NPO_1653
GO:0065009
<ncicp:ComplexDefinition><ncicp:def-definition>Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.</ncicp:def-definition></ncicp:ComplexDefinition>
regulation of molecular function
regulation of molecular function
GO:GO_0070265
NPO_1369
GO:0070265
<ncicp:ComplexDefinition><ncicp:def-definition>A cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.</ncicp:def-definition></ncicp:ComplexDefinition>
cellular necrosis
necrosis
cellular necrosis
PATO:PATO_0000004
NPO_1314
PATO:0000004
<ncicp:ComplexDefinition><ncicp:def-definition>A realizable entity inhering in an object by virtue of its ability to move or be moved freely.</ncicp:def-definition></ncicp:ComplexDefinition>
mobility
mobility
PATO:PATO_0000008
NPO_1316
PATO:0000008
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity inhering in an object by virtue of the rate of change of its position.</ncicp:def-definition><ncicp:Definition_Review_Date>100429</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
velocity
speed
velocity
PATO:PATO_0000044
NPO_1330
PATO:0000044
<ncicp:ComplexDefinition><ncicp:def-definition>The rate at which an event occurs or is repeated over a particular period of time.</ncicp:def-definition></ncicp:ComplexDefinition>
frequency
frequency
PATO:PATO_0000117
NPO_1225
PATO:0000117
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a bearer by virtue of its physical magnitude.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
size
size
PATO:PATO_0000119
NPO_1229
PATO:0000119
<ncicp:ComplexDefinition><ncicp:def-definition>A 1-D extent quality which is equal to the vertical dimension of extension.</ncicp:def-definition></ncicp:ComplexDefinition>
height
height
PATO:PATO_0000122
NPO_1227
PATO:0000122
<ncicp:ComplexDefinition><ncicp:def-definition>A 1-D extent quality which is equal to the distance between two points.</ncicp:def-definition></ncicp:ComplexDefinition>
length
length
PATO:PATO_0000125
NPO_1169
PATO:0000125
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality that inheres in a bearer in proportion to the amount of matter it contains. It is the property of a substance that causes it to have weight in a gravitational field.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
mass
mass
PATO:PATO_0000128
NPO_1218
PATO:0000128
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A force inhering in an object with mass near a gravitational body.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
weight
weight
PATO:PATO_0000146
NPO_1287
PATO:0000146
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality of the thermal energy of a system.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
temperature
temperature
PATO:PATO_0000169
NPO_1342
PATO:0000169
<ncicp:ComplexDefinition><ncicp:def-definition>A realizable entity inhering in a bearer or a population, by virtue of the bearer's ability or inability to survive and develop normally or the number of surviving individuals in a given population.</ncicp:def-definition></ncicp:ComplexDefinition>
viability
viability
PATO:PATO_0000547
NPO_1348
PATO:0000547
<ncicp:ComplexDefinition><ncicp:def-definition>A disposition inhering in a bearer by virtue of its exhibiting photosensitivity.</ncicp:def-definition></ncicp:ComplexDefinition>
photosensitive
photosensitive
PATO:PATO_0000915
NPO_1230
PATO:0000915
<ncicp:ComplexDefinition><ncicp:def-definition>A 1-D extent quality which is equal to the dimension through an object as opposed to its length or width.</ncicp:def-definition></ncicp:ComplexDefinition>
thickness
thickness
PATO:PATO_0000918
NPO_1238
PATO:0000918
<ncicp:ComplexDefinition><ncicp:def-definition>A 3-D extent quality of the amount of 3-dimensional space an object occupies.</ncicp:def-definition></ncicp:ComplexDefinition>
volume
volume
PATO:PATO_0000921
NPO_1231
PATO:0000921
<ncicp:ComplexDefinition><ncicp:def-definition>A 1-D extent quality which is equal to the distance from one side of an object to another side which is opposite.</ncicp:def-definition></ncicp:ComplexDefinition>
width
breadth
width
PATO:PATO_0000927
NPO_1347
PATO:0000927
<ncicp:ComplexDefinition><ncicp:def-definition>A disposition inhering to the bearer by virtue of its sensitivity to the action of radiant energy.</ncicp:def-definition></ncicp:ComplexDefinition>
photosensitivity
photosensitivity
PATO:PATO_0001018
NPO_1152
PATO:0001018
<ncicp:ComplexDefinition><ncicp:def-definition>A quality which exists through action of continuants at the physical level of organisation.</ncicp:def-definition></ncicp:ComplexDefinition>
physical quality
physical quality
PATO:PATO_0001019
NPO_1273
PATO:0001019
<ncicp:ComplexDefinition><ncicp:def-definition>A physical quality which inhers to the bearer by virtue of some influence exerted by its mass.</ncicp:def-definition></ncicp:ComplexDefinition>
density
density
PATO:PATO_0001035
NPO_1166
PATO:0001035
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity inhering in a object affecting its acceleration.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
force
force
PATO:PATO_0001242
NPO_1346
PATO:0001242
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A wave parameter which is equal to the distance between repeating units of a wave pattern.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
wavelength
wavelength
PATO:PATO_0001291
NPO_1385
PATO:0001291
<ncicp:ComplexDefinition><ncicp:def-definition>A quality that inheres in an object by virtue of how that object interacts with electromagnetic radiation.</ncicp:def-definition></ncicp:ComplexDefinition>
electromagnetic radiation quality
electromagnetic radiation quality
PATO:PATO_0001296
NPO_1387
PATO:0001296
<ncicp:ComplexDefinition><ncicp:def-definition>A scalar optical quality which obtains by the magnitude of the light emitted by the bearer.</ncicp:def-definition></ncicp:ComplexDefinition>
luminous quality
luminous quality
PATO:PATO_0001300
NPO_1386
PATO:0001300
<ncicp:ComplexDefinition><ncicp:def-definition>An EM radiation quality in which the EM radiation is within the fiat range of the spectrum visible deemed to be light.</ncicp:def-definition></ncicp:ComplexDefinition>
optical quality
optical quality
PATO:PATO_0001323
NPO_1234
PATO:0001323
<ncicp:ComplexDefinition><ncicp:def-definition>A 2-D extent inhering in a bearer by virtue of its two dimensional extent.</ncicp:def-definition></ncicp:ComplexDefinition>
area
area
PATO:PATO_0001334
NPO_1228
PATO:0001334
<ncicp:ComplexDefinition><ncicp:def-definition>A quality which is equal to the length of any straight line segment that passes through the center of a circle and whose endpoints are on the circular boundary.</ncicp:def-definition></ncicp:ComplexDefinition>
diameter
diameter
PATO:PATO_0001353
NPO_1274
PATO:0001353
<ncicp:ComplexDefinition><ncicp:def-definition>A density quality which is equal to the mass exerting an influence on a given volume.</ncicp:def-definition></ncicp:ComplexDefinition>
mass density
mass density
PATO:PATO_0001462
NPO_1301
PATO:0001462
<ncicp:ComplexDefinition><ncicp:def-definition>A quality inhering in a cell's plasma membrane by virtue of the electrical potential difference across it.</ncicp:def-definition></ncicp:ComplexDefinition>
membrane potential
membrane potential
PATO:PATO_0001464
NPO_1300
PATO:0001464
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity that is equal to the potential energy per unit charge associated with a static (time-invariant) electric field, also called the electrostatic potential.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
electric potential
electrostatic potential
electric potential
PATO:PATO_0001519
NPO_1349
PATO:0001519
<ncicp:ComplexDefinition><ncicp:def-definition>A quality inhering in a bearer by virtue of vibration, as perceived by the sense of hearing.</ncicp:def-definition></ncicp:ComplexDefinition>
sound quality
sound quality
PATO:PATO_0001520
NPO_1350
PATO:0001520
<ncicp:ComplexDefinition><ncicp:def-definition>The frequency of transmitted vibrations.</ncicp:def-definition></ncicp:ComplexDefinition>
frequency of sound wave
frequency of sound
frequency of sound wave
PATO:PATO_0001522
NPO_1352
PATO:0001522
<ncicp:ComplexDefinition><ncicp:def-definition>The speed at which sound travels in a given medium under specified conditions.</ncicp:def-definition></ncicp:ComplexDefinition>
speed of sound wave
speed of sound
velocity of sound
speed of sound wave
PATO:PATO_0001523
NPO_1353
PATO:0001523
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>The quotient of the speed of a sound wave divided by its frequency.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
wavelength of sound
wavelength of sound
PATO:PATO_0001595
NPO_1232
PATO:0001595
<ncicp:ComplexDefinition><ncicp:def-definition>A 1-D extent downward or backward or inward.</ncicp:def-definition></ncicp:ComplexDefinition>
depth
depth
PATO:PATO_0001679
NPO_1240
PATO:0001679
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality of the amount of 3-dimensional space a mass of substance occupies.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
specific volume
The reciprocal of density.
specific volume
PATO:PATO_0001680
NPO_1239
PATO:0001680
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality of the amount of 3-dimensional space a homogeneous substance containing 6.02 x 1023 atoms or molecules occupies.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
molar volume
molar volume
PATO:PATO_0001681
NPO_1170
PATO:0001681
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality that inheres in a homogeneous substance containing 6.02 x 1023 atoms or molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
molar mass
molar mass
PATO:PATO_0001682
NPO_1157
PATO:0001682
<ncicp:ComplexDefinition><ncicp:def-definition>A realizable entity which is a property inhering in a material entity by virtue of its ability to exert an attractive or repulsive force on other material entities.</ncicp:def-definition></ncicp:ComplexDefinition>
magnetism
magnetism
PATO:PATO_0001685
NPO_406
PATO:0001685
<ncicp:ComplexDefinition><ncicp:def-definition>A magnetic behavior exhibited 1) by materials which produce magnetic fields to exert attractive or repulsive forces on other materials or 2) by materials which become magnetized when exposed to a magnetic field.</ncicp:def-definition></ncicp:ComplexDefinition>
magnetic
magnetic behavior
magnetic
PATO:PATO_0001708
NPO_1226
PATO:0001708
<ncicp:ComplexDefinition><ncicp:def-definition>A quality inhering in an bearer by virtue of its extension in one dimension.</ncicp:def-definition></ncicp:ComplexDefinition>
1-D extent
1-D extent
PATO:PATO_0001709
NPO_1233
PATO:0001709
<ncicp:ComplexDefinition><ncicp:def-definition>A quality inhering in an bearer by virtue of its extenstion in two dimensions.</ncicp:def-definition></ncicp:ComplexDefinition>
2-D extent
2-D extent
PATO:PATO_0001710
NPO_1237
PATO:0001710
<ncicp:ComplexDefinition><ncicp:def-definition>A quality inhering in an bearer by virtue of its extenstion in three dimensions.</ncicp:def-definition></ncicp:ComplexDefinition>
3-D extent
3-D extent
PATO:PATO_0001711
NPO_1236
PATO:0001711
<ncicp:ComplexDefinition><ncicp:def-definition>A 2-D extent quality which is equal to the distance around a given two-dimensional object.</ncicp:def-definition></ncicp:ComplexDefinition>
perimeter
perimeter
PATO:PATO_0001739
NPO_1381
PATO:0001739
<ncicp:ComplexDefinition><ncicp:def-definition>A quality that inheres in an object by virtue of how that object interacts with radiation.</ncicp:def-definition></ncicp:ComplexDefinition>
radiation quality
radiation quality
PATO:PATO_0001842
NPO_1197
PATO:0001842
<ncicp:ComplexDefinition><ncicp:def-definition>A quality inhering in an entity by virtue of it containing acid (hydrogen ions).</ncicp:def-definition></ncicp:ComplexDefinition>
acidity
acidity
PATO:PATO_0001885
NPO_399
PATO:0001885
<ncicp:ComplexDefinition><ncicp:def-definition>A realizable property which inheres in a molecule that lacks affinity for water molecules, or has a tendency to repel or not to mix with water molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
hydrophobic
hydrophobicity
hydrophobic
PATO:PATO_0001887
NPO_204
PATO:0001887
<ncicp:ComplexDefinition><ncicp:def-definition>A realizable property which inheres in a molecule that has a strong affinity to a water molecule, or has a tendency to mix with or wetted by water molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
hydrophilic
hydrophilicity
hydrophilic
PATO:PATO_0001906
NPO_1313
PATO:0001906
<ncicp:ComplexDefinition><ncicp:def-definition>A quality inhering in a bearer by virtue of its participation in movement.</ncicp:def-definition></ncicp:ComplexDefinition>
movement quality
movement quality
REX:REX_0000002
NPO_1596
REX:0000002
<ncicp:ComplexDefinition><ncicp:def-definition>A process involving the interconversion of chemical species.</ncicp:def-definition></ncicp:ComplexDefinition>
chemical reaction
chemical reaction
REX:REX_0000038
NPO_1400
REX:0000038
<ncicp:ComplexDefinition><ncicp:def-definition>Luminescence arising from photoexcitation.</ncicp:def-definition></ncicp:ComplexDefinition>
photoluminescence
photoluminescence
REX:REX_0000043
NPO_1401
REX:0000043
<ncicp:ComplexDefinition><ncicp:def-definition>Photoluminescence which occurs essentially only during the irradiation of a substance by electromagnetic radiation.</ncicp:def-definition></ncicp:ComplexDefinition>
fluorescence
fluorescence
REX:REX_0000044
NPO_1444
REX:0000044
<ncicp:ComplexDefinition><ncicp:def-definition>A photoluminescence which is long-lived compared to fluorescence, and involves change in spin multiplicity, typically from triplet to singlet or vice versa. The luminescence from a quartet state to a doublet state is also phosphorescence.
[source: http://goldbook.iupac.org/P04569.htm]</ncicp:def-definition></ncicp:ComplexDefinition>
phosphorescence
phosphorescence
REX:REX_0000218
NPO_1631
REX_0000218
<ncicp:ComplexDefinition><ncicp:def-definition>The decrease in rate of reaction brought about by the addition of a substance (inhibitor), by virtue of its effect on the concentration of a reactant, catalyst or reaction intermediate.</ncicp:def-definition></ncicp:ComplexDefinition>
inhibition
inhibition
REX:REX_0000290
NPO_1399
REX:0000290
<ncicp:ComplexDefinition><ncicp:def-definition>Spontaneous emission of radiation from an electronically or vibrationally excited species not in thermal equilibrium with its environment.</ncicp:def-definition></ncicp:ComplexDefinition>
luminescence
luminescence
REX:REX_0000294
NPO_1402
REX:0000294
<ncicp:ComplexDefinition><ncicp:def-definition>Luminescence resulting from a chemical reaction.</ncicp:def-definition></ncicp:ComplexDefinition>
chemiluminescence
chemiluminescence
REX:REX_0000303
NPO_1398
REX:0000303
<ncicp:ComplexDefinition><ncicp:def-definition>Radioactive deactivation of an excited state of a material entity by which energy is transferred from the material entity to an electromagnetic field.</ncicp:def-definition></ncicp:ComplexDefinition>
emission
emission
UO:UO_0000000
NPO_1153
UO:0000000
<ncicp:ComplexDefinition><ncicp:def-definition>A quantitative measure of a property, which is a quantity chosen as a standard measure in terms of which other quantities (measured numerical values) are expressed in.</ncicp:def-definition></ncicp:ComplexDefinition>
unit of measurement
unit
unit of measurement
UO:UO_0000001
NPO_1241
UO:0000001
<ncicp:ComplexDefinition><ncicp:def-definition>A unit which is a standard measure of the distance between two points.</ncicp:def-definition></ncicp:ComplexDefinition>
length unit
unit of length
length unit
UO:UO_0000002
NPO_1172
UO:0000002
<ncicp:ComplexDefinition><ncicp:def-definition>A unit of measurement which is a standard measure of the amount of matter/energy of a physical object.</ncicp:def-definition></ncicp:ComplexDefinition>
mass unit
unit of mass
mass unit
UO:UO_0000003
NPO_1275
UO:0000003
<ncicp:ComplexDefinition><ncicp:def-definition>A base unit which is a standard measure of the dimension in which events occur in sequence.</ncicp:def-definition></ncicp:ComplexDefinition>
time unit
unit of time
time unit
UO:UO_0000005
NPO_1288
UO:0000005
<ncicp:ComplexDefinition><ncicp:def-definition>A unit which is a standard measure of the average kinetic energy of the particles in a sample of matter.</ncicp:def-definition></ncicp:ComplexDefinition>
temperature unit
unit of temperature
temperature unit
UO:UO_0000006
NPO_1216
UO:0000006
<ncicp:ComplexDefinition><ncicp:def-definition>A base unit which is a standardized quantity of an element or compound with uniform composition.</ncicp:def-definition></ncicp:ComplexDefinition>
substance unit
unit of amount of substance
substance unit
UO:UO_0000008
NPO_1242
UO:0000008
<ncicp:ComplexDefinition><ncicp:def-definition>A length unit which is equal to the length of the path traveled by light in vacuum during a time interval of 1/299 792 458 of a second.</ncicp:def-definition></ncicp:ComplexDefinition>
meter
m
meter
UO:UO_0000009
NPO_1179
UO:0000009
<ncicp:ComplexDefinition><ncicp:def-definition>A mass unit which is equal to the mass of the International Prototype Kilogram kept by the BIPM at Svres, France.</ncicp:def-definition></ncicp:ComplexDefinition>
kilogram
kg
kilogram
UO:UO_0000010
NPO_1276
UO:0000010
<ncicp:ComplexDefinition><ncicp:def-definition>A time unit which is equal to the duration of 9 192 631 770 periods of the radiation corresponding to the transition between the two hyperfine levels of the ground state of the caesium 133 atom.</ncicp:def-definition></ncicp:ComplexDefinition>
second
s
second
UO:UO_0000012
NPO_1291
UO:0000012
<ncicp:ComplexDefinition><ncicp:def-definition>A thermodynamic temperature unit which is equal to the fraction 1/273.16 of the thermodynamic temperature of the triple point of water.</ncicp:def-definition></ncicp:ComplexDefinition>
Kelvin
K
Kelvin
UO:UO_0000013
NPO_1221
UO:0000013
<ncicp:ComplexDefinition><ncicp:def-definition>A substance unit which is equal to the amount of substance of a molecular system which contains as many elementary entities as there are atoms in 0.012 kilogram of carbon 12.</ncicp:def-definition></ncicp:ComplexDefinition>
mole
mol
mole
UO:UO_0000015
NPO_1243
UO:0000015
<ncicp:ComplexDefinition><ncicp:def-definition>A length unit which is equal to one hundredth of a meter or 10^[-2] m.</ncicp:def-definition></ncicp:ComplexDefinition>
centimeter
cm
centimeter
UO:UO_0000016
NPO_1244
UO:0000016
<ncicp:ComplexDefinition><ncicp:def-definition>A length unit which is equal to one thousandth of a meter or 10^[-3] m.</ncicp:def-definition></ncicp:ComplexDefinition>
millimeter
mm
millimeter
UO:UO_0000017
NPO_1245
UO:0000017
<ncicp:ComplexDefinition><ncicp:def-definition>A length unit which is equal to one millionth of a meter or 10^[-6] m.</ncicp:def-definition></ncicp:ComplexDefinition>
micrometer
µm
micrometer
UO:UO_0000018
NPO_1246
UO:0000018
<ncicp:ComplexDefinition><ncicp:def-definition>A length unit which is equal to one thousandth of one millionth of a meter or 10^[-9] m.</ncicp:def-definition></ncicp:ComplexDefinition>
nanometer
nm
nanometer
UO:UO_0000019
NPO_1247
UO:0000019
<ncicp:ComplexDefinition><ncicp:def-definition>A length unit which is equal to 10 [-10] m.</ncicp:def-definition></ncicp:ComplexDefinition>
angstrom
A
angstrom
UO:UO_0000021
NPO_1180
UO:0000021
<ncicp:ComplexDefinition><ncicp:def-definition>A mass unit which is equal to one thousandth of a kilogram or 10^[-3] kg.</ncicp:def-definition></ncicp:ComplexDefinition>
gram
g
gram
UO:UO_0000022
NPO_1181
UO:0000022
<ncicp:ComplexDefinition><ncicp:def-definition>A mass unit which is equal to one thousandth of a gram or 10^[-3] g.</ncicp:def-definition></ncicp:ComplexDefinition>
milligram
mg
milligram
UO:UO_0000023
NPO_1182
UO:0000023
<ncicp:ComplexDefinition><ncicp:def-definition>A mass unit which is equal to one millionth of a gram or 10^[-6] g.</ncicp:def-definition></ncicp:ComplexDefinition>
microgram
µg
microgram
UO:UO_0000024
NPO_1183
UO:0000024
<ncicp:ComplexDefinition><ncicp:def-definition>A mass unit which is equal to one thousandth of one millionth of a gram or 10^[-9] g.</ncicp:def-definition></ncicp:ComplexDefinition>
nanogram
ng
nanogram
UO:UO_0000027
NPO_1289
UO:0000027
<ncicp:ComplexDefinition><ncicp:def-definition>A temperature unit on the Celsius scale based on which the freezing point of water is 0 degrees Celsius and the boiling point is 100 degree Celsius at standard conditions. Celsius scale has its zero at 273.15 K.</ncicp:def-definition></ncicp:ComplexDefinition>
degree celsius
deg. C
degree celsius
UO:UO_0000028
NPO_1277
UO:0000028
<ncicp:ComplexDefinition><ncicp:def-definition>A time unit which is equal to one thousandth of a second or 10^[-3] s.</ncicp:def-definition></ncicp:ComplexDefinition>
millisecond
ms
millisecond
UO:UO_0000029
NPO_1278
UO:0000029
<ncicp:ComplexDefinition><ncicp:def-definition>A time unit which is equal to one millionth of a second or 10^[-6] s.</ncicp:def-definition></ncicp:ComplexDefinition>
microsecond
µs
microsecond
UO:UO_0000031
NPO_1281
UO:0000031
<ncicp:ComplexDefinition><ncicp:def-definition>A time derived unit which is equal to 60 seconds.</ncicp:def-definition></ncicp:ComplexDefinition>
minute
min
minute
UO:UO_0000032
NPO_1282
UO:0000032
<ncicp:ComplexDefinition><ncicp:def-definition>A time unit which is equal to 3600 seconds or 60 minutes.</ncicp:def-definition></ncicp:ComplexDefinition>
hour
h
hour
UO:UO_0000033
NPO_1283
UO:0000033
<ncicp:ComplexDefinition><ncicp:def-definition>A time unit which is equal to 24 hours.</ncicp:def-definition></ncicp:ComplexDefinition>
day
day
UO:UO_0000034
NPO_1284
UO:0000034
<ncicp:ComplexDefinition><ncicp:def-definition>A time unit which is equal to 7 days.</ncicp:def-definition></ncicp:ComplexDefinition>
week
wk
week
UO:UO_0000035
NPO_1178
UO:0000035
<ncicp:ComplexDefinition><ncicp:def-definition>A time unit which is approximately equal to the length of time of one of cycle of the moon's phases which is taken to be equal to 30 days.</ncicp:def-definition></ncicp:ComplexDefinition>
month
month
UO:UO_0000036
NPO_1177
UO:0000036
<ncicp:ComplexDefinition><ncicp:def-definition>A time unit which is equal to 12 months.</ncicp:def-definition></ncicp:ComplexDefinition>
year
y
year
UO:UO_0000039
NPO_1223
UO:0000039
<ncicp:ComplexDefinition><ncicp:def-definition>A substance unit equal to a millionth of a mol or 10^[-6] mol.</ncicp:def-definition></ncicp:ComplexDefinition>
micromole
µmol
micromole
UO:UO_0000040
NPO_1222
UO:0000040
<ncicp:ComplexDefinition><ncicp:def-definition>A substance unit equal to a thousandth of a mol or 10^[-3] mol.</ncicp:def-definition></ncicp:ComplexDefinition>
millimole
mmol
millimole
UO:UO_0000041
NPO_1224
UO:0000041
<ncicp:ComplexDefinition><ncicp:def-definition>A substance unit equal to one thousandth of one millionth of a mole or 10^[-9] mol.</ncicp:def-definition></ncicp:ComplexDefinition>
nanomole
nmol
nanomole
UO:UO_0000047
NPO_1248
UO:0000047
<ncicp:ComplexDefinition><ncicp:def-definition>A unit which is a standard measure of the amount of a 2-dimensional surface.</ncicp:def-definition></ncicp:ComplexDefinition>
area unit
unit of area
area unit
UO:UO_0000051
NPO_1168
UO:0000051
<ncicp:ComplexDefinition><ncicp:def-definition>A unit which represents a standard measurement of how much of a given substance there is mixed with another substance.</ncicp:def-definition></ncicp:ComplexDefinition>
concentration unit
unit of concentration
concentration unit
UO:UO_0000052
NPO_1264
UO:0000052
<ncicp:ComplexDefinition><ncicp:def-definition>A density unit which is a standard measure of the mass of a substance in a given volume.</ncicp:def-definition></ncicp:ComplexDefinition>
mass density unit
unit of mass density
mass density unit
UO:UO_0000055
NPO_1184
UO:0000055
<ncicp:ComplexDefinition><ncicp:def-definition>A unit which is a standard measure of the mass of a homogeneous substance containing 6.02 x 1023 atoms or molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
molar mass unit
unit of molar mass
molar mass unit
UO:UO_0000056
NPO_1260
UO:0000056
<ncicp:ComplexDefinition><ncicp:def-definition>A unit which is a standard measure of the volume of a homogeneous substance containing 6.02 x 1023 atoms or molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
molar volume unit
unit of molar volume
molar volume unit
UO:UO_0000060
NPO_1328
UO:0000060
<ncicp:ComplexDefinition><ncicp:def-definition>A standard measure of the rate of movement. Speed is measured in the same physical units of measurement as velocity, but does not contain the element of direction that velocity has. Speed is thus the magnitude component of velocity.</ncicp:def-definition></ncicp:ComplexDefinition>
unit of velocity
unit of speed
unit of velocity
UO:UO_0000061
NPO_1187
UO:0000061
<ncicp:ComplexDefinition><ncicp:def-definition>A concentration unit which is a standard measure of the number of moles of a given substance per liter of solution.</ncicp:def-definition></ncicp:ComplexDefinition>
unit of molarity
unit of molarity
UO:UO_0000062
NPO_1207
UO:0000062
<ncicp:ComplexDefinition><ncicp:def-definition>A unit of concentration which expresses a concentration of 1 mole of solute per liter of solution (mol/L).</ncicp:def-definition></ncicp:ComplexDefinition>
molar
M
molar
UO:UO_0000063
NPO_1208
UO:0000063
<ncicp:ComplexDefinition><ncicp:def-definition>A unit of molarity which is equal to one thousandth of a molar or 10^[-3] M.</ncicp:def-definition></ncicp:ComplexDefinition>
millimolar
mM
millimolar
UO:UO_0000064
NPO_1209
UO:0000064
<ncicp:ComplexDefinition><ncicp:def-definition>A unit of molarity which is equal to one millionth of a molar or 10^[-6] M.</ncicp:def-definition></ncicp:ComplexDefinition>
micromolar
µM
micromolar
UO:UO_0000065
NPO_1210
UO:0000065
<ncicp:ComplexDefinition><ncicp:def-definition>A unit of molarity which is equal to one thousandth of one millionth of a molar or 10^[-9] M.</ncicp:def-definition></ncicp:ComplexDefinition>
nanomolar
nM
nanomolar
UO:UO_0000067
NPO_1188
UO:0000067
<ncicp:ComplexDefinition><ncicp:def-definition>A concentration unit which is a standard measure of the number of moles of a given solute per kilogram of solvent.</ncicp:def-definition></ncicp:ComplexDefinition>
unit of molality
unit of molality
UO:UO_0000068
NPO_1211
UO:0000068
<ncicp:ComplexDefinition><ncicp:def-definition>A unit of concentration which expresses a concentration of a solution of 1 mole per kilogram of solvent (mol/kg).</ncicp:def-definition></ncicp:ComplexDefinition>
molal
mol/kg
molal
UO:UO_0000069
NPO_1212
UO:0000069
<ncicp:ComplexDefinition><ncicp:def-definition>A molality unit which is equal to one thousandth of a molal or 10^[-3] m.</ncicp:def-definition></ncicp:ComplexDefinition>
millimolal
mmol/kg
millimolal
UO:UO_0000070
NPO_1213
UO:0000070
<ncicp:ComplexDefinition><ncicp:def-definition>A molality unit which is equal to one millionth of a molal or 10^[-6] m.</ncicp:def-definition></ncicp:ComplexDefinition>
micromolal
µmol/kg
micromolal
UO:UO_0000071
NPO_1214
UO:0000071
<ncicp:ComplexDefinition><ncicp:def-definition>A molality unit which is equal to one thousandth of one millionth of a molal or 10^[-9] m.</ncicp:def-definition></ncicp:ComplexDefinition>
nanomolal
nmol/kg
nanomolal
UO:UO_0000074
NPO_1189
UO:0000074
<ncicp:ComplexDefinition><ncicp:def-definition>A concentration unit which is a standard measure of the number gram equivalents of solute per liter of solution.</ncicp:def-definition></ncicp:ComplexDefinition>
unit of normality
unit of normality
UO:UO_0000075
NPO_1215
UO:0000075
<ncicp:ComplexDefinition><ncicp:def-definition>A unit of concentration which is one gram equivalent of a solute per liter of solution. A gram equivalent weight or equivalent is a measure of the reactive capacity of a given molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
normal
N
normal
UO:UO_0000080
NPO_1249
UO:0000080
<ncicp:ComplexDefinition><ncicp:def-definition>An area unit which is equal to an area enclosed by a square with sides each 1 meter long.</ncicp:def-definition></ncicp:ComplexDefinition>
square meter
m^[2]
square meter
UO:UO_0000081
NPO_1250
UO:0000081
<ncicp:ComplexDefinition><ncicp:def-definition>An area unit which is equal to one thousand of square meter or 10^[-3] m^[2].</ncicp:def-definition></ncicp:ComplexDefinition>
square centimeter
cm^[2]
square centimeter
UO:UO_0000082
NPO_1251
UO:0000082
<ncicp:ComplexDefinition><ncicp:def-definition>An area unit which is equal to one millionth of a square meter or 10^[-6] m^[2].</ncicp:def-definition></ncicp:ComplexDefinition>
square millimeter
mm^[2]
square millimeter
UO:UO_0000083
NPO_1269
UO:0000083
<ncicp:ComplexDefinition><ncicp:def-definition>A mass density unit which is equal to mass of an object in kilograms divided by the volume in cubic meters.</ncicp:def-definition></ncicp:ComplexDefinition>
kilogram per cubic meter
kg/m^[3]
kilogram per cubic meter
UO:UO_0000084
NPO_1270
UO:0000084
<ncicp:ComplexDefinition><ncicp:def-definition>A mass density unit which is equal to mass of an object in grams divided by the volume in cubic centimeters.</ncicp:def-definition></ncicp:ComplexDefinition>
gram per cubic centimeter
g/cm^[3]
grams per cubic centimeter
gram per cubic centimeter
UO:UO_0000087
NPO_1185
UO:0000087
<ncicp:ComplexDefinition><ncicp:def-definition>A molar mass unit which is equal to one kilogram of mass of one mole of chemical element or chemical compound.</ncicp:def-definition></ncicp:ComplexDefinition>
kilogram per mole
kg/mol
kilogram per mole
UO:UO_0000088
NPO_1186
UO:0000088
<ncicp:ComplexDefinition><ncicp:def-definition>A molar mass unit which is equal to one gram of mass of one mole of chemical element or chemical compound.</ncicp:def-definition></ncicp:ComplexDefinition>
gram per mole
g/mol
gram per mole
UO:UO_0000089
NPO_1261
UO:0000089
<ncicp:ComplexDefinition><ncicp:def-definition>A molar volume unit which is equal to 1 cubic meter occupied by one mole of a substance in the form of a solid, liquid, or gas.</ncicp:def-definition></ncicp:ComplexDefinition>
cubic meter per mole
m^[3]/mol
cubic meter per mole
UO:UO_0000090
NPO_1262
UO:0000090
<ncicp:ComplexDefinition><ncicp:def-definition>A molar volume unit which is equal to 1 cubic centimeter occupied by one mole of a substance in the form of a solid, liquid, or gas.</ncicp:def-definition></ncicp:ComplexDefinition>
cubic centimeter per mole
cm^[3]/mol
cubic centimeter per mole
UO:UO_0000094
NPO_1329
UO:0000094
<ncicp:ComplexDefinition><ncicp:def-definition>A speed/velocity unit which is equal to the speed of an object traveling 1 meter distance in one second.</ncicp:def-definition></ncicp:ComplexDefinition>
meter per second
m/s
meter per second
UO:UO_0000095
NPO_1253
UO:0000095
<ncicp:ComplexDefinition><ncicp:def-definition>A unit which is a standard measure of the amount of space occupied by any substance, whether solid, liquid, or gas.</ncicp:def-definition></ncicp:ComplexDefinition>
volume unit
unit of volume
volume unit
UO:UO_0000096
NPO_1254
UO:0000096
<ncicp:ComplexDefinition><ncicp:def-definition>A volume unit which is equal to the volume of a cube with edges one meter in length. One cubic meter equals to 1000 liters.</ncicp:def-definition></ncicp:ComplexDefinition>
cubic meter
m^[3]
cubic meter
UO:UO_0000097
NPO_1255
UO:0000097
<ncicp:ComplexDefinition><ncicp:def-definition>A volume unit which is equal to one millionth of a cubic meter or 10^[-9] m^[3], or to 1 ml.</ncicp:def-definition></ncicp:ComplexDefinition>
cubic centimeter
cc
cm^[3]
cubic centimeter
UO:UO_0000098
NPO_1256
UO:0000098
<ncicp:ComplexDefinition><ncicp:def-definition>A volume unit which is equal to one thousandth of a liter or 10^[-3] L, or to 1 cubic centimeter.</ncicp:def-definition></ncicp:ComplexDefinition>
milliliter
mL
milliliter
UO:UO_0000099
NPO_1257
UO:0000099
<ncicp:ComplexDefinition><ncicp:def-definition>A volume unit which is equal to one thousandth of a cubic meter or 10^[-3] m^[3], or to 1 decimeter.</ncicp:def-definition></ncicp:ComplexDefinition>
liter
L
liter
UO:UO_0000101
NPO_1258
UO:0000101
<ncicp:ComplexDefinition><ncicp:def-definition>A volume unit which is equal to one millionth of a liter or 10^[-6] L.</ncicp:def-definition></ncicp:ComplexDefinition>
microliter
µL
microliter
UO:UO_0000102
NPO_1259
UO:0000102
<ncicp:ComplexDefinition><ncicp:def-definition>A volume unit which is equal to one thousandth of one millionth of a liter or 10^[-9] L.</ncicp:def-definition></ncicp:ComplexDefinition>
nanoliter
nL
nanoliter
UO:UO_0000105
NPO_1331
UO:0000105
<ncicp:ComplexDefinition><ncicp:def-definition>A unit which is a standard measure of the number of repetitive actions in a particular time.</ncicp:def-definition></ncicp:ComplexDefinition>
frequency unit
frequency unit
UO:UO_0000106
NPO_1332
UO:0000106
<ncicp:ComplexDefinition><ncicp:def-definition>A frequency unit which is equal to 1 complete cycle of a recurring phenomenon in 1 second.</ncicp:def-definition></ncicp:ComplexDefinition>
hertz
Hz
hertz
UO:UO_0000107
NPO_1173
UO:0000107
<ncicp:ComplexDefinition><ncicp:def-definition>A unit of measurement for the force applied to accelerate a mass (an amount of matter).</ncicp:def-definition></ncicp:ComplexDefinition>
force unit
unit of force
force unit
UO:UO_0000108
NPO_1174
UO:0000108
<ncicp:ComplexDefinition><ncicp:def-definition>A force unit which is equal to the force required to cause an acceleration of 1m/s2 of a mass of 1 Kg in the direction of the force.</ncicp:def-definition></ncicp:ComplexDefinition>
Newton
N
Newton
UO:UO_0000150
NPO_1279
UO:0000150
<ncicp:ComplexDefinition><ncicp:def-definition>A time unit which is equal to one thousandth of one millionth of a second or 10^[-9] s.</ncicp:def-definition></ncicp:ComplexDefinition>
nanosecond
ns
nanosecond
UO:UO_0000152
NPO_1280
UO:0000152
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity which inheres in a chemical or element which represents the period over which the amount, activity or concentration of a specified chemical or element falls to half its original amount, activity or concentration. The realization is the observation of change in the concentration, activity or amount of the bearer.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
half life
t1/2
half life
UO:UO_0000163
NPO_1324
NCIT:C48528
UO:0000163
<ncicp:ComplexDefinition><ncicp:def-definition>A percentage unit of concentration which denotes the mass of a substance in a mixture as a percentage of the mass of the entire mixture.</ncicp:def-definition></ncicp:ComplexDefinition>
percent mass per mass
% w/w
w/w %
mass percentage
percent weight per weight
percent weight/weight
weight-weight percentage
percent mass per mass
UO:UO_0000164
NPO_1326
NCIT:C48527
UO:0000164
<ncicp:ComplexDefinition><ncicp:def-definition>A percentage unit concentration which denotes the mass of the substance in a mixture as a percentage of the volume of the entire mixture.</ncicp:def-definition></ncicp:ComplexDefinition>
percent mass per volume
% w/v
mass volume percentage
percent weight per volume
weight-volume percentage
percent mass per volume
UO:UO_0000165
NPO_1325
NCIT:C48571
UO:0000165
<ncicp:ComplexDefinition><ncicp:def-definition>A percentage unit concentration which denotes the volume of the solute in mL per 100 mL of the resulting solution.</ncicp:def-definition></ncicp:ComplexDefinition>
percent volume per volume
% v/v
% vol
percent volume
percent volume/volume
volume percentage
percent volume per volume
UO:UO_0000166
NPO_1319
UO:0000166
<ncicp:ComplexDefinition><ncicp:def-definition>A dimensionless concentration notation which describes the amount of one substance in another.</ncicp:def-definition></ncicp:ComplexDefinition>
parts per notation
parts per notation
UO:UO_0000168
NPO_1322
UO:0000168
<ncicp:ComplexDefinition><ncicp:def-definition>A dimensionless concentration notation which denotes the amount of a given substance in a total amount of 1000 regardless of the units of measure as long as they are the same.</ncicp:def-definition></ncicp:ComplexDefinition>
parts per thousand
ppth
parts per thousand
UO:UO_0000169
NPO_1321
UO:0000169
<ncicp:ComplexDefinition><ncicp:def-definition>A dimensionless concentration notation which denotes the amount of a given substance in a total amount of 1,000,000 regardless of the units of measure used as long as they are the same or 1 part in 10^[6].</ncicp:def-definition></ncicp:ComplexDefinition>
parts per million
ppm
parts per million
UO:UO_0000173
NPO_1265
UO:0000173
<ncicp:ComplexDefinition><ncicp:def-definition>A mass density unit which is equal to mass of an object in grams divided by the volume in milliliter.</ncicp:def-definition></ncicp:ComplexDefinition>
gram per milliliter
g/mL
grams per milliliter
gram per milliliter
UO:UO_0000174
NPO_1272
UO:0000174
<ncicp:ComplexDefinition><ncicp:def-definition>A mass density unit which is equal to mass of an object in kilograms divided by the volume in liters.</ncicp:def-definition></ncicp:ComplexDefinition>
kilogram per liter
kg/L
kilograms per liter
kilogram per liter
UO:UO_0000175
NPO_1271
UO:0000175
<ncicp:ComplexDefinition><ncicp:def-definition>A mass density unit which is equal to mass of an object in grams divided by the volume in liters.</ncicp:def-definition></ncicp:ComplexDefinition>
gram per liter
g/L
grams per liter
gram per liter
UO:UO_0000176
NPO_1266
UO:0000176
<ncicp:ComplexDefinition><ncicp:def-definition>A mass density unit which is equal to mass of an object in milligrams divided by the volume in milliliters.</ncicp:def-definition></ncicp:ComplexDefinition>
milligram per milliliter
mg/mL
milligrams per milliliter
milligram per milliliter
UO:UO_0000182
NPO_1263
UO:0000182
<ncicp:ComplexDefinition><ncicp:def-definition>A unit which is a standard measure of the influence exerted by some mass.</ncicp:def-definition></ncicp:ComplexDefinition>
density unit
unit of density
density unit
UO:UO_0000186
NPO_1154
UO:0000186
<ncicp:ComplexDefinition><ncicp:def-definition>A unit of measurement of which is dimensionless.</ncicp:def-definition></ncicp:ComplexDefinition>
dimensionless unit
dimensionless unit
UO:UO_0000187
NPO_1323
UO:0000187
<ncicp:ComplexDefinition><ncicp:def-definition>A ratio unit which denotes numbers as fractions of 100.</ncicp:def-definition></ncicp:ComplexDefinition>
percent
%
percentage
percent
UO:UO_0000189
NPO_1320
UO:0000189
<ncicp:ComplexDefinition><ncicp:def-definition>A dimensionless unit which denotes a simple count of things.</ncicp:def-definition></ncicp:ComplexDefinition>
count
count
UO:UO_0000195
NPO_1290
UO:0000195
<ncicp:ComplexDefinition><ncicp:def-definition>A temperature unit on the Fahrenheit scale in which the freezing point of water is 32 degrees Fahrenheit and the boiling point is 212 degrees at standard conditions, placing the boiling and freezing points of water 180 degrees apart. -40 degrees Fahrenheit is equal to -40 degrees Celsius.</ncicp:def-definition></ncicp:ComplexDefinition>
degree Fahrenheit
deg. F
degree Fahrenheit
UO:UO_0000196
NPO_1198
UO:0000196
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>The logarithm of the reciprocal of hydrogen-ion concentration in gram atoms per liter. (source:Princeton WordNet)</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>WordNet</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
pH
pH
UO:UO_0000200
NPO_1194
UO:0000200
<ncicp:ComplexDefinition><ncicp:def-definition>A concentration unit which denotes the average cell number in a given volume.</ncicp:def-definition></ncicp:ComplexDefinition>
unit of cell concentration
unit of cell concentration
UO:UO_0000201
NPO_1205
UO:0000201
<ncicp:ComplexDefinition><ncicp:def-definition>A unit of cell concentration which is equal to one cell in a volume of 1 milliliter.</ncicp:def-definition></ncicp:ComplexDefinition>
cells per milliliter
cells/mL
cells per milliliter
UO:UO_0000217
NPO_1295
UO:0000217
<ncicp:ComplexDefinition><ncicp:def-definition>A standard measure of the work done per unit charge as a charge is moved between two points in an electric field.</ncicp:def-definition></ncicp:ComplexDefinition>
electric potential difference unit
unit of electric potential
unit of electric potential difference
electric potential difference unit
UO:UO_0000218
NPO_1296
UO:0000218
<ncicp:ComplexDefinition><ncicp:def-definition>An electric potential difference unit which is equal to the work per unit charge. One volt is the potential difference required to move one coulomb of charge between two points in a circuit while using one joule of energy.</ncicp:def-definition></ncicp:ComplexDefinition>
volt
V
volt
UO:UO_0000220
NPO_1294
UO:0000220
<ncicp:ComplexDefinition><ncicp:def-definition>An electrical charge unit which is equal to the amount of charge transferred by a current of 1 ampere in 1 second.</ncicp:def-definition></ncicp:ComplexDefinition>
coulomb
C
coulomb
UO:UO_0000221
NPO_1175
UO:0000221
<ncicp:ComplexDefinition><ncicp:def-definition>A mass unit which is equal to one twelfth of the mass of an unbound atom of the carbon-12 nuclide, at rest and in its ground state.</ncicp:def-definition></ncicp:ComplexDefinition>
dalton
Da
dalton
UO:UO_0000222
NPO_1176
UO:0000222
<ncicp:ComplexDefinition><ncicp:def-definition>A mass unit which is equal to one thousand daltons.</ncicp:def-definition></ncicp:ComplexDefinition>
kilodalton
kDa
kilodalton
UO:UO_0000226
NPO_1160
UO:0000226
<ncicp:ComplexDefinition><ncicp:def-definition>A unit of magnetic flux which is equal to the amount of flux that when linked with a single turn of wire for an interval of one second will induce an electromotive force of one volt.</ncicp:def-definition></ncicp:ComplexDefinition>
weber
V s
Wb
volt-second
weber
UO:UO_0000228
NPO_1165
UO:0000228
<ncicp:ComplexDefinition><ncicp:def-definition>A unit of magnetic flux density which is equal to one weber per square meter.</ncicp:def-definition></ncicp:ComplexDefinition>
Tesla
T
Wb/m^[2]
Tesla
UO:UO_0000229
NPO_1161
UO:0000229
<ncicp:ComplexDefinition><ncicp:def-definition>A unit of magnetic flux which is equal to 3600 Wb.</ncicp:def-definition></ncicp:ComplexDefinition>
volt-hour
Vh
volt-hour
UO:UO_0000230
NPO_1162
UO:0000230
<ncicp:ComplexDefinition><ncicp:def-definition>A unit of magnetic flux which is equal to one thousand volt-hours.</ncicp:def-definition></ncicp:ComplexDefinition>
kilovolt-hour
kV h
kilovolt-hour
UO:UO_0000247
NPO_1297
UO:0000247
<ncicp:ComplexDefinition><ncicp:def-definition>An electric potential difference unit which is equal to one thousandth of a volt or 10^[-3] V.</ncicp:def-definition></ncicp:ComplexDefinition>
millivolt
mV
millivolt
UO:UO_0000248
NPO_1298
UO:0000248
<ncicp:ComplexDefinition><ncicp:def-definition>An electric potential difference unit which is equal to 10^[3] V.</ncicp:def-definition></ncicp:ComplexDefinition>
kilovolt
kV
kilovolt
UO:UO_0000249
NPO_1299
UO:0000249
<ncicp:ComplexDefinition><ncicp:def-definition>An electric potential difference unit which is equal to one millionth of a volt or 10^[-6] V.</ncicp:def-definition></ncicp:ComplexDefinition>
microvolt
µV
microvolt
UO:UO_0000259
NPO_1354
UO:0000259
<ncicp:ComplexDefinition><ncicp:def-definition>A unit which is an indicator of sound power per unit area.</ncicp:def-definition></ncicp:ComplexDefinition>
decibel
dB
decibel
bfo:Entity
NPO_258
<ncicp:ComplexDefinition><ncicp:def-definition>An entity is a thing which exists in reality.</ncicp:def-definition></ncicp:ComplexDefinition>
entity
entity
snap:Continuant
NPO_259
snap:Continuant
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An entity [bfo:Entity] that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
continuant
endurant
Examples: a heart, a person, the color of a tomato, the mass of a cloud, a symphony orchestra, the disposition of blood to coagulate, the lawn and atmosphere in front of our building
continuant
snap:DependentContinuant
NPO_607
snap:DependentContinuant
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A continuant [snap:Continuant] that is either dependent on one or other independent continuant [snap:IndependentContinuant] bearers or inheres in or is borne by other entities.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
dependent continuant
In order for a dependent continuant to exist, some other entity must exist.
dependent_continuant
snap:Disposition
NPO_155
snap:Disposition
<ncicp:ComplexDefinition><ncicp:def-definition>A realizable entity [snap:RealizableEntity] that essentially causes a specific process or transformation in the object [snap:Object] in which it inheres, under specific circumstances and in conjunction with the laws of nature. A general formula for dispositions is: X (object [snap:Object] has the disposition D to (transform, initiate a process) R under conditions C.</ncicp:def-definition></ncicp:ComplexDefinition>
disposition
Source:Robert Arp and Barry Smith "Function, Role and Disposition in Basic Formal Ontology" NATURE PROCEEDINGS, 2008.
The process occurs as a result of the object's physical structure. A disposition invariably or definitely leads to a certain result given certain circumstances (if not, then the realizable entity is a tendency and not a disposition).
disposition
snap:Function
NPO_316
snap:Function
<ncicp:ComplexDefinition><ncicp:def-definition>A realizable entity [snap:RealizableEntity] the manifestation of which is an essentially end-directed activity of a continuant [snap:Continuant] entity in virtue of that continuant [snap:Continuant] entity being a specific kind of entity in the kind or kinds of contexts that it is made for.</ncicp:def-definition></ncicp:ComplexDefinition>
function
A realizable entity, which is a necessary function of the bearer, and it is realized as an end-directed activity (a process in which the bearer is a participant).
[source]: (1) BFO.owl 1.1; (2) Robert Arp and Barry Smith "Function, Role and Disposition in Basic Formal Ontology" NATURE PROCEEDINGS, 2008.
a function "f" is a realizable dependent continuant; it has a bearer which is an independent continuant; instances of Function F have realizations; each realization is a) a process in which the bearer is participant; b) that It occurs in virtue of the bearer's physical make-up or structure. c) and this physical make-up is something which the bearer possesses because of how it came into being.
function
snap:GenericallyDependentContinuant
NPO_1600
snap:GenericallyDependentContinuant
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A continuant [snap:Continuant] that is dependent on one or other independent continuant [snap:IndependentContinuant] bearers. For every instance of A requires some instance of (an independent continuant [snap:IndependentContinuant] type) B but which instance of B serves can change from time to time. Examples: a certain PDF file that exists in different and in several hard drives</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
generically dependent continuant
Examples: a certain PDF file that exists in different and in several hard drives
generically_dependent_continuant
snap:IndependentContinuant
NPO_118
snap:IndependentContinuant
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A continuant [snap:Continuant] that is a bearer of quality [snap:Quality] and realizable entity [snap:RealizableEntity] entities, in which other entities inhere and which itself cannot inhere in anything.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
independent continuant
substantial entity
independent_continuant
snap:OneDimensionalRegion
NPO_1665
snap:OneDimensionalRegion
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spatial region [snap:SpatialRegion] with one dimension.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
one_dimensional_region
one_dimensional_region
snap:Quality
NPO_445
snap:Quality
<ncicp:ComplexDefinition><ncicp:def-definition>A specifically dependent continuant [snap:SpecificallyDependentContinuant] that is exhibited if it inheres in an entity or entities at all (a categorical property).</ncicp:def-definition></ncicp:ComplexDefinition>
quality
Example: compound x is related to organic compound through the relation "presence of carbon"; here, the quality that inheres in compound x is organic)
Examples: the color of a tomato, the ambient temperature of air, the circumference of a waist, the shape of a nose, the mass of a piece of gold, the weight of a chimpanzee
quality
snap:RealizableEntity
NPO_237
snap:RealizableEntity
<ncicp:ComplexDefinition><ncicp:def-definition>A specifically dependent continuant [snap:SpecificallyDependentContinuant] that inheres in continuant [snap:Continuant] entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances.</ncicp:def-definition></ncicp:ComplexDefinition>
realizable entity
Source: (1) BFO.owl v. 1.1; (2) Robert Arp and Barry Smith "Function, Role and Disposition in Basic Formal Ontology" NATURE PROCEEDINGS, 2008.
realizable entities are defined by the fact that they can be realized (manifested, actualized, executed) in occurrents of corresponding sorts.
realizable_entity
snap:Role
NPO_517
snap:Role
<ncicp:ComplexDefinition><ncicp:def-definition>A realizable entity [snap:RealizableEntity] the manifestation of which brings about some result or end that is not essential to a continuant [snap:Continuant] in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant [snap:Continuant] in some kinds of natural, social or institutional contexts.</ncicp:def-definition></ncicp:ComplexDefinition>
role
At the instance-level, a role y is filled by x which is an instance of an independent continuant( x which takes the role of y: x is the filler, y is the role). A role y has a context P (e.g. an occurrent in which x is a participant). Every role term has its own qualities and behavior, given the context.
role is a realizable_entity whose manifestation brings about some result or end that is not typical of its bearer in virtue of the latter's physical structure. Rather role is played by an instance of the corresponding kind of continuant entity because this entity is in some special natural, social or institutional set of circumstances. (Source: Robert Arp and Barry Smith "Function, Role and Disposition in Basic Formal Ontology" NATURE PROCEEDINGS, 2008.)
role
snap:SpatialRegion
NPO_1664
snap:SpatialRegion
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A continuant [snap:Continuant] that is neither bearer of quality [snap:Quality] entities nor inheres in any other entities.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
spatial_region
spatial_region
snap:SpecificallyDependentContinuant
NPO_1601
snap:SpecificallyDependentContinuant
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A continuant [snap:Continuant] that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
specifically dependent continuant
Synonyms: property, trope, mode; Examples: the mass of a cloud, the smell of mozzarella, the liquidity of blood, the color of a tomato, the disposition of fish to decay, the role of being a doctor, the function of the heart in the body: to pump blood, to receive de-oxygenated and oxygenated blood, etc.
specifically_dependent_continuant
snap:ThreeDimensionalRegion
Examples: a cube-shaped part of space, a sphere-shaped part of space.
NPO_1667
snap:ThreeDimensionalRegion
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spatial region [snap:SpatialRegion] with three dimensions.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
three_dimensional_region
three_dimensional_region
snap:TwoDimensionalRegion
NPO_1666
snap:TwoDimensionalRegion
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spatial region [snap:SpatialRegion] with two dimensions.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
two_dimensional_region
two_dimensional_region
snap:ZeroDimensionalRegion
Example: A point.
NPO_1668
snap:ZeroDimensionalRegion
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spatial region [snap:SpatialRegion] with no dimensions.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
zero_dimensional_region
zero_dimensional_region
span:ConnectedSpatiotemporalRegion
NPO_1671
span:ConnectedSpatiotemporalRegion
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spatiotemporal region [span:SpatiotemporalRegion] that has temporal and spatial dimensions such that all points within the spatiotemporal region are mediately or immediately connected to all other points within the same spatiotemporal region [span:SpatiotemporalRegion].</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
connected_spatiotemporal_region
connected_spatiotemporal_region
span:ConnectedTemporalRegion
Examples: the 1970s years, the time from the beginning to the end of a heart attack, the time taken by cellular meiosis.
NPO_1676
span:ConnectedTemporalRegion
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A temporal region [span:TemporalRegion] every point of which is mediately or immediately connected with every other point of which.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
connected_temporal_region
connected_temporal_region
span:FiatProcessPart
NPO_417
span:FiatProcessPart
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A processual entity [span:ProcessualEntity] that is part of a process but that does not have bona fide beginnings and endings corresponding to real discontinuities.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
fiat process part
[source]: BFO v. 1.1
is it synonymous with "stage" which refers to temporally distinguised parts of an occurrent (eg., "infancy", "childhood", "adolescence", "adulthood" in the "life of a human being")?
fiat_process_part
span:Occurrent
NPO_923
span:Occurrent
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An entity [bfo:Entity] that has temporal parts and that happens, unfolds or develops through time. Sometimes also called perdurants.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
occurrent
perdurant
Examples: the life of an organism, a surgical operation as processual context for a nosocomical infection, the spatiotemporal context occupied by a process of cellular meiosis, the most interesting part of Van Gogh's life, the spatiotemporal region occupied by the development of a cancer tumor
occurrent
span:Process
NPO_336
span:Process
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A processual entity [span:ProcessualEntity] that is a maximally connected spatiotemporal whole and has bona fide beginnings and endings corresponding to real discontinuities.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
process
[definition source]: BFO
process
span:ProcessAggregate
NPO_397
span:ProcessAggregate
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A processual entity [span:ProcessualEntity] that is a mereological sum of process [span:Process] entities and possesses non-connected boundaries.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
process aggregate
[source]: BFO v. 1.1
process_aggregate
span:ProcessBoundary
NPO_137
span:ProcessBoundary
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A processual entity [span:ProcessualEntity] that is the fiat or bona fide instantaneous temporal process boundary.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
process boundary
[source]: BFO v. 1.1
process_boundary
span:ProcessualContext
NPO_1669
span:ProcessualContext
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An occurrent [span:Occurrent] consisting of a characteristic spatial shape inhering in some arrangement of other occurrent [span:Occurrent] entities. Processual context [span:ProcessualContext] entities are characteristically entities at or in which other occurrent [span:Occurrent] entities can be located or occur.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
processual_context
Examples: The processual context for a given manipulation occurring as part of an experiment is made of processual entities which occur in parallel, are not necessarily all parts of the experiment themselves and may involve continuant [snap:Continuant] entities which are in the spatial vicinity of the participants in the experiment. An instance of a processual context [span:ProcessualContext] is a mixture of processual entity [span:ProcessualEntity] which stand as surrounding environments for other processual entity [span:ProcessualEntity] entities. The class processual context [span:ProcessualContext] is the analogous among occurrent [span:Occurrent] entities to the class site [snap:Site] among continuant [snap:Continuant] entities.
processual_context
span:ProcessualEntity
NPO_703
span:ProcessualEntity
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An occurrent [span:Occurrent] that exists in time by occurring or happening, has temporal parts and always involves and depends on some entity.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
processual entity
[source]: BFO v. 1.1
processual_entity
span:ScatteredSpatiotemporalRegion
NPO_1672
span:ScatteredSpatiotemporalRegion
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spatiotemporal region [span:Spatiotemporal Region] that has spatial and temporal dimensions and every spatial and temporal point of which is not connectedd with every other spatial and temporal point of which.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
scattered_spatiotemporal_region
scattered_spatiotemporal_region
span:ScatteredTemporalRegion
Examples: The time occupied by the indiviual games of the World Cup.
NPO_1677
span:ScatteredTemporalRegion
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A temporal region [span:TemporalRegion] every point of which is not mediately or immediately connected with every other point of which.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
scattered_temporal_region
scattered_temporal_region
span:SpatiotemporalInstant
NPO_1673
span:SpatiotemporalInstant
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A connected spatiotemporal region [span:ConnectedSpatiotemporalRegion] at a specific moment.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
spatiotemporal_instant
spatiotemporal_instant
span:SpatiotemporalInterval
NPO_1674
span:SpatiotemporalInterval
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A connected spatiotemporal region [span:ConnectedSpatiotemporalRegion] at a specific moment.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
spatiotemporal_interval
spatiotemporal_interval
span:SpatiotemporalRegion
NPO_1670
span:SpatiotemporalRegion
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An occurrent [span:Occurrent] at or in which processual entity [span:ProcessualEntity] entities can be located.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
spatiotemporal_region
spatiotemporal_region
span:TemporalInstant
Examples: right now, the moment at which a finger is detached in an industrial accident, the moment at which a child is born, the moment of death.
NPO_1678
span:TemporalInstant
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A connected temporal region [span:ConnectedTemporalRegion] comprising a single moment of time.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
temporal_instant
temporal_instant
span:TemporalInterval
Examples: any continuous temporal duration during which a process occurs.
NPO_1679
span:TemporalInterval
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A connected temporal region [span:ConnectedTemporalRegion] lasting for more than a single moment of time.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
temporal_interval
temporal_interval
span:TemporalRegion
Examples: the time it takes to run a marathon, the duration of a surgical procedure, the moment of death.
NPO_1675
span:TemporalRegion
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An occurrent [span:Occurrent] that is part of time.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
temporal_region
temporal_region
owl:Thing
2011-12-08 (yyyy-mm-dd)
Dennis G. Thomas
NanoParticle Ontology (NPO) represents the knowledge underlying the description, synthesis and characterization of nanoparticle formulations. The NPO provides the knowledge framework to support the annotation and semantic integration of data related to nanoparticles formulated in nanomedicine and nanotoxicology research. The NPO uses the Basic Formal Ontology (BFO) as its upper-level ontology and also uses terms from other biomedical ontologies to achieve interoperability with the other ontologies and to facilitate its expansion.
http://purl.bioontology.org/ontology/npo
The NPO was primarily developed by Dennis G. Thomas in collaboration with Nathan A. Baker and Rohit V. Pappu. This development was supported by the NIH through grants U54 CA119342 and U54 HG004028.
Currently, the NCI caBIG Nanotechnology Working Group (Nano WG) supports the use and development of the NPO.
NPO JIRA Tracker: https://tracker.nci.nih.gov/browse/NPO
2011-12-08 (yyyy-mm-dd)
Used to support Merge and Retire
DesignNote
It begins with the prefix "NPO_" followed by a number (e.g., NPO_250). The smallest code value is NPO_100 of class Cylinder.
The property code is used to indicate a unique identification code for every class in the NPO.
code
The property dBXrefID is used to indicate the reference ID of a class from an external CV / ontology / database.
dBXrefID
The property definition is used to indicate the meaning or definition of a class or a class-level association in the NPO.
definition
The property preferred name is used to indicate the preferred name of a class or a class-level association in the NPO.
preferred_name
The property symbol is used to enter a symbol that denotes the name of an entity.
symbol
The property synonym is used to indicate an alternate name of a class or a class-level association in the NPO.
synonym