Scalene Muscle
A small fold of tissue that limits the movements of an organ or body part; for example, the lingual frenulum connects the tongue to the floor of the mouth and restrains its movement.
Frenulum
Posterior Portion of the Urethra
The portion of the urethra that is located on the posterior aspect of the urogenital diaphragm.
URETHRA, POSTERIOR
Foramen of Monroe
Interventricular Foramen
Physical location of CNK1_Gene
1: 26188145-26200517
8: 37826569-37820563
Physical location of BRF2_Gene
The longest single nerve that is formed by the merging of the ventral rami of the L4, L5, and S1 in the pelvis and passes down the lower limb where it divides into the common peroneal and tibial nerves.
Sciatic Nerve
NERVE, SCIATIC
Physical location of EIF2B1_Gene
12: 122642993-122630453
The sex chromosome that is present in both sexes: singly in males and doubly in females.
X Chromosome
Chromosome X
3p14.1
A chromosome band present on 3p
9p21-p12
A chromosome band present on 9p
Physical location of AXIN1_Gene
16: 342465-277441
Medial Palpebral Ligament
Inferior Anastomotic Vein of Labbe
Inferior Anastomotic Vein of the Labbe
1p36.1
A chromosome band present on 1p
Lingual Artery
11: 125001547-125030847
Physical location of CHEK1_Gene
14: 19993130-19995766
Physical location of APEX1_Gene
2q32.2
A chromosome band present on 2q
15: 73792151-73754019
Physical location of CSPG4_Gene
A mesodermal precursor of germ cells, detectable at four weeks of fetal development. It originates in the allantois and then migrates through the hindgut and into the genital ridge, where it proliferates and differentiates into an oogonia or spermatogonia cell.
Primordial Germ Cell
Postganglionic Sympathetic Fiber
Nerve fibers which project from sympathetic ganglia to synapses on target organs. Sympathetic postganglionic fibers use norepinephrine as transmitter, except for those innervating eccrine sweat glands (and possibly some blood vessels) which use acetylcholine. They may also release peptide cotransmitters. (MeSH)
Sympathetic Fibers, Postganglionic
S3 Vertebra
The cartilage that covers the ends of each bone in a joint.
Articular Cartilage
Tracheal Bud
Chromosome Y
The male sex chromosome, being the differential sex chromosome carried by half the male gametes and none of the female gametes in man and in some other male-heterogametic species in which the homologue of the X chromosome has been retained.
Y Chromosome
11: 63808740-63793878
Physical location of BAD_Gene
Male Reproductive System Part
Lower Esophageal Sphincter
LES
Perineurial Cell
A cell that belongs to the supporting tissue surrounding a nerve fiber bundle. It has thin long bipolar cytoplasmic processes, pinocytotic vesicles, fragments of external lamina and/or external lamina-like material, attachment plaques, and desmosome-like junctions.
A chromosome band present on 10q
10q22-q23
Stylopharyngeus
bHLH-Zip Domain
Tripartite DNA binding domain containing a basic region, a helix-loop-helix, and a leucine zipper.
6: 34312628-34321986
Physical location of HMGA1_Gene
15q11.2-q21.3
A chromosome band present on 15q
A chromosome band present on 16q
16q24.2-q24.3
A chromosome band present on 2q
2q11.2-q12
Axoaxonic Synapse
A synapse between the axons of two neurons.
Rib Head
5: 39430280-39408488
Physical location of DAB2_Gene
Two cup shaped areas, one each on the lateral side of the lower pelvis that house the head of the femur to form the ball and socket joint of the hip.
Acetabulum
A chromosome band present on 1p
1p36.3
A chromosome band present on 2q
2q23-q24
Longissimus Thoracis
Perineural Cell
A cell surrounding a neuron.
The hemispheric projection, including the mammary gland, located on the anterior portion of the chest, lateral to the midline, on the side of the body to the west when facing north.
Left Breast
16: 78192112-78185751
Physical location of MAF_Gene
Fifth Ventricle
Cavity of Septum Pellucidum
Cavity of the Septum Pellucidum
Coated Vesicle
A cytoplasmic vesicle that is coated with proteins which stabilize its structure and facilitate targeting.
17: 35425214-35427592
Physical location of CSF3_Gene
Gastrocolic Ligament
Extrahepatic Bile Duct
The portion of the biliary tract outside the liver; the common hepatic duct joins the cystic duct to form the common bile duct.
Neural Pathways
Neural Pathway
Neural tracts connecting one part of the nervous system with another. (MeSH)
Left Lung Bronchiole
Spinal Nerve Plexus
Chief Cell (Stomach)
Chief Cells, Gastric
An epithelial cell of the stomach that secretes digestive enzymes. Chief cells may be found at any level in the fundic glands, but are most common in the deeper region, toward the muscularis mucosae. They are basophilic.
Chief Cell of the Stomach
Internal Ear
Labyrinth
EAR, INNER
INNER EAR
Cochlea
The portion of the ear located within the temporal bone that is involved in both hearing and balance and includes the semicircular canals, vestibule, and cochlea. (from American Heritage Dictionary online)
1p36.2
A chromosome band present on 1p
Involuntary muscle tissue of the internal organs. It is composed of elongated muscle cells or fibers that are not arranged in a striated pattern and form layers of muscle tissue. The smooth muscle cells contain a contractile apparatus composed of thin and thick filaments and a cytoskeleton composed of intermediate filaments.
Smooth Muscle Tissue
Smooth Muscle
MUSCLE, SMOOTH
External Anal Sphincter
Physical location of BMP7_Gene
20: 55274708-55178962
2q21.3
A chromosome band present on 2q.
Winged Helix
The winged helix is a common, 100 amino acid DNA-binding domain which is a variant of the helix-turn-helix motif found in the "forkhead" transcription factor gene family.
1: 3592286-3673013
Physical location of TP73_Gene
Lamellipodia
A sheet-like cellular projection that is supported by an ordered network of actin microfilaments. This structure is involved in cellular motility and can define the leading edge of a migrating cell.
A chromosome band present on 7q
7q11.2
Left Ovary
Renal Pelvis
The funnel-shaped proximal portion of the ureter located within the kidney into which urine is secreted, from the collecting duct system of the kidney.
Physical location of C3_Gene
19: 6671660-6628878
Fourth Pharyngeal Pouch
Adrenal Gland Tissue
GLAND, ADRENAL
The tissue that forms the adrenal gland. It consists of the outer adrenal cortex and the inner adrenal medulla.
Kringle Domain
Kringle
Kringles are autonomous structural domains, found throughout the blood clotting and fibrinolytic proteins. Kringle domains are believed to play a role in binding mediators (e.g., membranes, other proteins or phospholipids), and in the regulation of proteolytic activity. Kringle domains are characterised by a triple loop, 3-disulphide bridge structure, whose conformation is defined by a number of hydrogen bonds and small pieces of anti-parallel beta-sheet. They are found in a varying number of copies, in some serine proteases and plasma proteins.
Vaginal Epithelium
Ovarian Surface Epithelium
11p13-p12
A chromosome band present on 11p
13q
Chromosome 13 Distal Arm
Chromosome 13 Long Arm
Distal (long) arm of chromosome 13
Mammary Epithelium
The epithelium that lines the lactiferous ducts and the secretory alveoli. The mammary epithelium in the lactiferous duct is a two layered epithelium. The basal cells are cuboidal and the superficial cells are columnar. Branches of the lactiferous duct are lined with a simple cuboidal epithelium. The secretory alveoli are lined by a cuboidal or columnar epithelium. During the first half of pregnancy, the epithelium undergoes considerable growth leading to the formation of new terminal branches of ducts and of alveoli. The mammary glands continue to grow during the second half of pregnancy due to increases in the height of epithelial cells and an expansion of the lumen of the alveoli.
A chromosome band present on 6q
6q13-q21
STOMACH, PYLORUS
The lower part of the stomach that connects to the duodenum.
Pylorus
7q11.1
A chromosome band present on 7q
The fluid that is excreted by the kidneys. It is stored in the bladder and discharged through the urethra.
Urine
Urinary System, Urine
A chromosome band present on 2q
2q21.1
Middle Cardiac Vein
Trachea Basement Membrane
EYE, CHOROID
Choroid
A blood vessel-containing membrane of the eye that lies between the retina and the sclera.
Fasciculata Zone
Renal Medulla
Medullary Portion of the Kidney
KIDNEY, MEDULLA
Medullary Portion of Kidney
That side of the tooth facing the midline.
Mesial Surface
Mesial
Olfactory Mucosa
The part of the nasal mucosa composed of neuroepithelial tissue and mucus-producing Bowman's glands. The mucus moistens the epithelium and helps dissolve odor-containing gases.
MUCOSA, NASAL
Fluids surrounding or related to an embryo.
Embryonic Fluid
Embryonic Fluids
Embryonic Tissue, Fluids, Secretions
Regions of chromosomal DNA attached to structural components of metaphase (condensed) chromosomes, permitting the partitioning of DNA in the chromosomes into looped domains. Appear to be related to similar regions denoted matrix-attachment regions that partition the chromosomal DNA in interphase chromosomes.
Scaffold-Associated Region
16q22-q23
A chromosome band present on 16q
Zinc-binding, DNA-binding motifs in proteins contain amino acids that are folded into a single DNA-binding structural unit around a zinc atom.
Zinc Finger Domain
Zinc Finger
Zinc-Binding, DNA-Binding Motif
Human Veru Montanum
Pancreatic Vein
Pillar Cell
A flattened cell that rests on the tympanic lip of the spiral lamina (inner pillar cell) and on the basilar membrane (outer pillar cell), thereby forming the tunnel of the Organ of Corti.
Outer Canthus
Physical location of SMARCD3_Gene
7: 150409988-150373707
Trachea Cartilage
1q21
A chromosome band present on 1q
Intercostal Fascia
3p14.2
A chromosome band present on 3p
Chromosome 15 Physical Location
Layer of the Ophthalmic Nerve Fibers
Interlobular Bile Duct
Pharyngeal Arch
The first, permanent, six-year molar of the lower right arch as defined by the Universal tooth numbering system.
Tooth 30
Tooth #30
Six-year Molar
First Molar
The lower right 2nd molar, as defined by the Universal tooth numbering system.
Tooth 31
Intrahepatic Portion of the Right Hepatic Duct
Frontal Horn of the Lateral Ventricle
A vein that drains blood from the cranium into the common cardinal vein during embryonic development.
Anterior Cardinal Vein
The quarter of the breast which is superior and lateral.
Upper-Outer Quadrant of the Breast
Upper-outer Quadrant of Breast
Antrum Pylori
Gastric Antrum
The initial part of the pyloric canal of the stomach. This site contains endocrine cells that produce gastrin and somatostatin.
Pectinate Line
A thin space between the outer and inner mitochondrial membranes formed by an invagination of the inner mitochondrial membrane.
Mitochondrial Crista
Physical location of ITK_Gene
5: 156540485-156614687
Lumbosacral Region
The mucous lining of the canal of the cervix uteri. It is composed of epithelium, basement membrane, lamina propria mucosae, and lamina muscularis mucosae.
Endocervical Mucosa
Nucleolar-Associated Chromatin
Heterochromatin that is associated with the nucleolus.
Physical location of FCGR2B_Gene
1: 158364622-158379489
The cellular material of blood consisting of white blood cells and nucleated red blood cells.
Nucleated Blood Cell
Tooth 32
The lower right 3rd molar, as defined by the Universal tooth numbering system.
Embryonic Nervous System
Subendocardial Layer
Bronchus Cartilage
1: 27634715-27622953
Physical location of FGR_Gene
Cerebral Peduncle
Intestinal Mucosa
22: 21847106-21982698
Physical location of BCR_Gene
Red Fiber
A chromosome band present on Xq
Xq13.1
Inferior Temporal Sulcus
Lateral Domain of the Epithelium
Proximal (short) arm of chromosome 13
13p
Chromosome 13 Proximal Arm
Chromosome 13 Short Arm
A chromosome band present on 1q
1q32.2
Right Pulmonary Vein
Mature T-Lymphocyte
Mature T-Cell
A lymphocyte derived from a pre T-lymphocyte in the thymus and stored in secondary lymphoid organs, bone marrow, and lymph nodes. It circulates in the bloodstream and the lymphatic system, where it searches for and attacks particular foreign or abnormal cells. A mature T lymphocyte has T cell receptors and other surface proteins on its cell surface.
Posterior Surface of the Stomach
Physical location of GLIPR2_Gene
9: 36126742-36153903
Bone Marrow Stem Cell with Predominant Neutrophil Differentiation
A primitive, undifferentiated blood cell which can undergo division and usually gives rise to a white blood cell in the neutrophil lineage.
Small Intestinal Glandular Cell
A glandular cell found in the epithelium of the small intestine.
Xiphisternum
The cartilage just below the sternal body.
Xiphoid Process
A consensus sequence found in the promoter region of most genes transcribed by eukaryotic RNA polymerase II. It is found about 25 nucleotides before the site of initiation of transcription and has the consensus sequence: 5' TATAAAA 3'. This sequence seems to be important in determining accurately the position at which transcription is initiated.
TATA Box
Xq13.2
A chromosome band present on Xq.
SAC, YOLK
Membranous sac on the ventral aspect of the developing embryo that acts as a primitive circulatory system as well as providing nourishment.
Yolk Sac
A superficial vein that is located on the cerebellum and that drains the cerebellum.
Cerebellar Vein
Nephrogenic Blastemal Cell
A pitlike depression or tubular recess.
Crypt
Physical location of EXT1_Gene
8: 119193239-118880787
5: 176556527-176457733
Physical location of FGFR4_Gene
Inner Plexiform Layer
Ampulla
11: 1979276-1973489
Physical location of H19_Gene
1q32.1
A chromosome band present on 1q
A thin membrane that lines the ventricles of the brain and the central canal of the spinal cord.
Ependymal Tissue
Ependyma
Venous System
Head and Neck Muscle
Primary Cerebral Vesicle
Primary Brain Vesicle
Physical location of GDNF_Gene
5: 37875539-37851510
ADAM Type Metalloprotease Domain
ADAMs are transmembrane proteins containing both a disintegrin and a metalloprotease domain. Two thirds of the proteins with an ADAM type metalloprotease domain also contain the zinc protease pattern which locates the active site of these proteases. As they contain an adhesion domain and a protease domain, ADAM proteins potentially have both cell adhesion and protease activities. They play a role in various biological processes, including fertilization, neurogenesis, myogenesis, embryonic TGF-alpha release and inflammatory response. In ADAMTS proteins, a closely related family of proteases, the metalloprotease and disintegrin domains are flanked by thrombospondin type I (TSP1) repeat. ADAMTS proteins are soluble, extracellular matrix proteases. (From InterPro IPR001590)
Thorax
The division of the body lying between the neck and the abdomen.
Left Pulmonary Artery
A long, branching outgrowth or extension from a neuron, that carries electrical signals from synapses to the cell body; any structure that resembles a dendrite.
Dendritic
Dendrite
Canal of Wirsung
Ducts that collect pancreatic juice from thepancreas and supply it to the duodenum. (MeSH)
Pancreatic Duct
The components of the cell.
Cell Component
Cell Part
Gastro-Hepatic Omentum
Lesser Omentum
The double layer of peritoneum that extends from the lesser curvature of the stomach and the start of the duodenum to the liver.
A chromosome band present on 13q
13q12.3
Hypogastric Nerve Plexus
Cutaneous Vein
Osseous
BONE
Osseous Tissue
The mineralized osseous tissue that gives rigidity to the bones and forms its honeycomb-like three-dimensional internal structure.
Bone Tissue
Otic Pit
Mastoid Process
A honeycombed section of bone located near the base of the skull, protruding behind the outer ear. It is connected to the middle ear.
Mastoid
Process Mastoideus
Flat Bone
Occipital Sulcus
Chromosome Y Physical Location
Left Lung Terminal Bronchiole
20: 42723790-42681578
Physical location of ADA_Gene
1p32-p31
A chromosome band present on 1p
A cell that composes the bulk of the islets of Langerhans and secretes insulin.
Insulin Cell
Insulin Secreting Cell
Beta Cell
Hippocampal Fissure
Dentate Fissure
A shallow groove between the dentate gyrus and the parahippocampal gyrus; the remains of a fissure extending deep into the hippocampus between Ammon's horn and the dentate gyrus which becomes obliterated during foetal development.
5: 175042318-475044164
Physical location of HRH2_Gene
Right Lung Terminal Bronchiole
Sural Artery
External Sural Artery
Superficial Sural Artery
Gracilis
Bronchial Vein
Couinaud segment VII, corresponding to the posterior segment of the right lobe of the liver, located superiorly.
Couinaud Segment VII
Right Posterosuperior Segment
Interstitial Cell of the Pineal Gland
A non-neuronal cell that supports the pineal gland. It resembles an astrocyte and is found around blood vessels and among groups of pinealocytes. The nucleus is small, elongated and darkly stained.
Cell Membrane
Cellular Membrane
Any of the lipid bilayer membranes within a cell.
8p12-p11.2
A chromosome band present on 8p
A coronary artery that arises from the aorta and bifurcates into the left anterior descending artery and the left circumflex artery.
Left Coronary Artery
CORONARY ARTERY, LEFT
Intestinal Villus
Villus
intestinal villi
Activated Natural Killer Cell
A cell that acts in a similar manner to a cytotoxic T cell and must be activated like a cytotoxic T cell. However, the killing exhibited by the cell is nonspecific and the cell does not require antigen/MHC recognition on the target cell. The lineage of the natural killer (NK) cell is currently not well understood.
Epithelial Tissue
Scalenus Dorsalis
4: 75229451-775226395
Physical location of CXCL5_Gene
Villus Tip
The distal end of a villus.
7: 26978389-26975298
Physical location of HOXA9_Gene
A chromosome band present on 8p
8p22-p21.3
Ellipsoid Portion of the Inner Segment of the Photoreceptor Cell
Finger
Any of the digits of the hand.
Cervical Nerve
Cartilaginous Tissue
A type of connective tissue composed of chondrocytes and an extracellular matrix, composed of collagen, elastin, and ground substance. There are three types of cartilage; namely elastic, hyaline, and fibrocartilage.
Cartilaginous
CARTILAGE
Vagina
birth canal
Genital System, Female, Vagina
The female genital canal, extending from the uterus to the vulva.
Lysosome Proton Pump
A protein complex found in the membrane of the lysosome that transports hydrogen ions into the lumen to increase its acidity.
Lysosome Proton
H+ Pump
Physical location of IL3_Gene
5: 131424246-131426795
spermatospore
The primitive differentiated male gamete which gives rise to a spermatocyte. (MeSH)
spermospore
Spermatogonium
Spermatophores
spermigonium
spermatogone
Spermatogonias
Spermatogonia
Any of the secretions of the breast.
Breast Fluid or Secretion
Breast Fluids and Secretions
Mammary Gland Fluids and Secretions
A chromosome band present on 2p
2p13.1
3: 107070518-106859808
Physical location of CBLB_Gene
Superior Oblique Muscle
Physical location of IGFBP4_Gene
17: 35853236-35867457
8q21-q22
A chromosome band present on 8q
Node of Ranvier
Periosteal Layer of the Dura Mater
Splenic Lymphoid Follicle
B-Cell Zone of the Spleen
B-Cell Zone of Spleen
Basal Layer
Stratum Basale
1: 39923389-39892996
Physical location of BMP8_Gene
Papillary Dermis
The upper portion of the dermis beneath the epidermis. It is composed of thin collagen fibers.
Parotid Duct
Stensen's Duct
Connective Tissue of Villus
The watery fluid which is present in the anterior and posterior chambers of the eye.
Aqueous Humor
Physical location of IL1B_Gene
2: 113310587-113303568
A flap of mucosal, and possibly gingival, tissue including the periosteum, reflected from bone and created in the process of conducting orthodontic surgery.
Mucoperiosteal Flap
Cleaved Cell
Cleaved
2p13.2
A chromosome band present on 2p
Lymphatic Basin
One of two small paired endocrine glands, superior and inferior, usually found embedded in the connective tissue capsule on the posterior surface of the thyroid gland; these glands secrete parathyroid hormone that regulates the metabolism of calcium and phosphorus. The parenchyma is composed of chief and oxyphilic cells arranged in anastomosing cords.
Head and Neck, Parathyroid
Parathyroid
Parathyroid Gland
Tertiary Chorionic Villus
11p11.2-p11.1
A chromosome band present on 11p
The supporting structure for the prostate. A dense layer of smooth muscle tissue lies directly underneath the fibrous capsule and another dense layer of circular fibers surrounds the urethra (striated and smooth). In between these two layers is a mesh of smooth muscle tissue in which the prostatic glands are embedded.
Prostatic Muscular Tissue
Human Prostatic Muscular Tissue
Lesser Tuberosity
Lesser Tuberosity of the Humerus
Arachnoidal Cell
Meningothelial Cell
Lobule
Upper Lobe of the Left Lung
LUNG, LEFT UPPER LOBE
The smaller lobe of the left lung, situated above and in front the oblique fissure, which includes the apex.
Superior Lobe of the Left Lung
Lung Left Upper Lobe
Upper Lobe of Left Lung-LUL
Upper Lobe of the Left Lung-LUL
9: 77875746-77564747
Physical location of GNAQ_Gene
Lumbar Sympathetic Nerve Trunk
Epaxial Division of the Myotome
Epaxial Division of Myotome
X: 133319777-133360216
Physical location of HPRT1_Gene
Superior Semicircular Canal
Posterior Cranial Fossa
The infratentorial compartment of the cranial cavity. Its boundaries are formed by the sphenoid bone, temporal bone, and parietal bone, and it contains the cerebellum and brain stem.
Tonsillar Pillar
7q22.3
A chromosome band present on 7q
Inferior Hypophyseal Artery
Lobe of the Left Lung
Physical location of ABCC1_Gene
16: 15950935-16143774
Bronchial Epithelium
CA1 Field of the Cornu Ammonis
D5S346 Dinucleotide Repeat
A dinucleotide repeat on chromosome 5 that serves as a marker for microsatellite instability in colorectal cancers.
D5S346
Hand Skin
Physical location of FYN_Gene
6: 112301320-112089178
A gland in the margins of the eyelids that opens into the follicles of the eyelashes and produces secretions that lubricate the eyeball.
Ciliary Gland
Gland of Moll
Fallopian Tube
Fallopian Tubes
OVIDUCT
One of a pair of tubes that extend from the uterus to each of the ovaries. Following ovulation the egg travels down the fallopian tube to the uterus where fertilization may or may not occur.
7q22.2
A chromosome band present on 7q
7p22-p15
A chromosome band present on 7p
A mononucleotide repeat that serves as a marker for microsatellite instability in colorectal cancers.
BAT25
BAT25 poly(A) Repeat
Red-colored, striated conical structures of the medullary portion of the kidney. The number of these structures varies from eight to eighteen.
Pyramid of Malpighi
Median Artery
The cartilage positioned between the anterior end of the rib and the sternum. Its elasticity allows the ribcage to expand while breathing.
Costal Cartilage
Humerus
BONE, HUMERUS
Bone, Humeral
The upper arm bone between the shoulder and elbow.
Goblet Cell
Cells of the epithelial lining that produce and secrete mucins. (MeSH)
Goblet Cells
Physical location of BMP5_Gene
6: 55848334-55728199
Physical location of DHPS_Gene
19: 12653677-12647534
A chromosome band present on 4q
4q31.23
4q
Distal (long) arm of chromosome 4
Chromosome 4 Distal Arm
Chromosome 4 Long Arm
Pineal Parenchyma
Pineal Body
GLAND, PINEAL
The tissue of the pineal gland. The pineal gland is a small reddish-gray body, about 8 mm. in length which lies in the depression between the superior colliculi. It is attached to the roof of the third ventricle near its junction with the mid-brain. It develops as an outgrowth from the third ventricle of the brain. The pineal parenchyma consists of follicles lined by epithelium and enveloped by connective tissues. It produces and secretes melatonin.
1: 109803343-109849017
Physical location of GNAI3_Gene
The inner aspect of the sclera, located adjacent to the choroid. It contains thin collagen fibers and elastic fibers, fibroblasts, melanocytes, macrophages, and other connective tissue cells.
Lamina Fusca
Suprachorioid Lamina
Melanocytes
Melanocyte
Physical location of COL18A1_Gene
21: 45649525-45758062
Lamina Terminalis Cistern
A lipid bilayer that bounds a peroxisome.
Membrane of the Peroxisome
Pancreatic Bud
AIR SAC
The terminal dilation of an alveolar duct that gives rise to alveoli in the lung.
Alveolar Sac
Secretory Vesicle
A vesicle that transports molecules that are targeted for cellular excretion.
Hepatic Lobule
Vestibular Nerve
Vestibular Root of Eighth Cranial Nerve
Vestibular Nerve (VIII)
Liver Stem Cell
An undifferentiated cell found in the liver.
Liver Stem Cells
1p21.3
A chromosome band present on 1p.
A thin membrane in the central part of the renal glomerulus between capillaries. It helps to support the capillary loops in the glomerulus. Mesangial cells are phagocytic and for the most part separated from capillary lumina by endothelial cells.
Mesangium
Inner Canthus
Vitreous Chamber
BRAIN, MEDULLA OBLONGATA
Medullary
Myelencephalon
The lower portion of the brainstem located between the pons and brainstem. This structure contains several descending and ascending tracts, lower cranial nerve nuclei, a significant proportion of the reticular system of the brainstem and other structures.
Medulla Oblongata
Regions near to the aorta.
Paraaortic Region
Paraaortic
Nucleolar Fibrillar Material
Pars Fibrosa
A thread-like complex of ribosomal components including ribosomal RNA, in various stages of transcription, and associated proteins.
Mediastinal Lymph Node
A lymph node located in the mediastinum. Mediastinal lymph nodes are arranged in three groups, one on the lateral, another on the medial, and a third on the anterior aspect of the vessels; the third group is, however, sometimes absent.
LYMPH NODE, MEDIASTINAL
Physical location of MADH4_Gene
18: 46810611-4680145
Physical location of LOC118430_Gene
12: 53534588-53538370
Physical location of FASN_Gene
17: 77649395-77629503
Free Nerve Endings
Free Nerve Ending
Free nerve endings are widely distributed throughout the body, and are found as branches of unmyelinated, or lightly myelinated fibres grouped in bundles beneath the epithelium. As they penetrate the epithelium, they lose their myelin, and branch among the epithelial cells. Branches of one nerve may cover a wide area and overlap the territories of other nerves. The free nerve endings detect pain, touch, pressure and temperature, and are associated with C fibres.
Chromosome 7q31
A chromosome band present on 7q
7q31
Peritoneal Cavity
BODY CAVITY, PERITONEAL
The lower part of the abdomen that contains the intestines (the last part of the digestive tract), the stomach, and the liver. It is bound by thin membranes.
An epithelial cell located in the inner portion of the thymus where the T lymphocytes become mature and are released into the circulation.
Thymic Medullary Epithelial Cell
A sense organ needed for the detection of sound and for establishing balance. The outer ear consists of the auricle, the ear canal as well as the tympanic membrane. The middle ear is made up of an air-filled cavity behind the tympanic membrane that contains the ossicles (malleus, incus and stapes). The inner ear is made up of the cochlea needed for hearing and the vestibular apparatus required for balance.
Ear
16: 73843004-73820430
Physical location of BCAR1_Gene
Distal Connecting Fiber
A protein complex associated with the distal end of the centriole which that is involved in centriole localization.
11: 62097927-62083649
Physical location of EEF1G_Gene
Gastrointestinal Tract
Digestive Tract
Gut
Alimentary Canal
The upper gastrointestinal (GI) tract is comprised of mouth, pharynx, esophagus and stomach while the lower GI tract consists of intestines and anus. The primary function of the GI tract is to ingest, digest, absorb and ultimately excrete food stuff.
Upper Jaw
BONE, MAXILLA
Maxillary
Maxilla
The upper jawbone in vertebrates; it is fused to the cranium.
Renal Pelvis Urothelial Cell
Renal Pelvis Transitional Cell
The anterior aspect of the bladder wall.
Anterior Wall of the Bladder
Anterior Wall of Bladder
The tenth thoracic vertebra counting from the top down.
T10 Vertebra
The short, constricted portion of the thigh bone between the femur head and the trochanter.
Neck of Femur
Femoral Neck
8: 13416766-12985243
Physical location of DLC1_Gene
The striated muscle tissue of the heart enveloped by the epicardium and the endocardium.
Myocardial Tissue
Heart Muscle
CARDIAC MUSCLE TISSUE
Cardiac Muscle
Myocardium
A protein region consisting of a very small variety of residues, including homopolymeric runs, short-period repeats, and more subtle overrepresentation of one or a few residues. (from BioInformatics Glossary: big.mcw.edu)
Low Complexity Region
LCR
Blood
A liquid tissue; its major function is to transport oxygen throughout the body. It also supplies the tissues with nutrients, removes waste products, and contains various components of the immune system defending the body against infection. Several hormones also travel in the blood.
Peripheral Blood
Reticuloendothelial System, Blood
A muscle fiber that is able to hydrolyze ATP and transmit electrochemical signals rapidly.
Fast-twitch Motor Unit
BAT26 poly(A) Repeat
BAT26
A mononucleotide repeat that serves as a marker for microsatellite instability in colorectal cancers.
Masseteric Artery
Inner Hair Cell of Organ of Corti
A cell situated on the inner most layer of the basilar membrane of the cochlea. Each cell has multiple, sensitive strands called stereocilia. In the resting state the stereocilia are leaning on each other in a conical bundle and touch the tectorial membrane. When the cochlea moves in response to sound, a slight shearing force occurs between the basilar and tectorial membranes, the stereocilia bend and send electrical impulses to the brain via the eighth cranial nerve.
Inner Hair Cell of the Organ of the Corti
8p11.2
A chromosome band present on 8p
The area between the clivus and the petrous portion of the temporal bone.
Petroclival Region
Physical location of BDP1_Gene
5: 70787261-70877060
Pars Media of the External Acoustic Meatus
Pars Media
Proximal (short) arm of chromosome 4
4p
Chromosome 4 Short Arm
Chromosome 4 Proximal Arm
A chromosome band present on 4q
4q35.1
Round, granular, mononuclear phagocytes found in the alveoli of the lungs. They ingest small inhaled particles resulting in degradation and presentation of the antigen to immunocompetent cells.
Alveolar Macrophage
Macrophages, Alveolar
Pulmonary Macrophages
8q21-q24
A chromosome band present on 8q
Lumbar Curve
Appendix
Small tissue projection existing as a cecal diverticulum with a questionable history of vestigial versus specialized organ.
Vermiform Appendix
LARGE INTESTINE, APPENDIX
1q23
A chromosome band present on 1q
Labial Salivary Gland
Purkinje Fiber
Hyaline Cartilage
Epithelia of lung alveoli. The layer of cells covering the lining of the tiny air sacs at the end of the bronchioles.
Lung Alveolar Epithelia
Alveolar Epithelium
Nervous System, Eye
The components of the eye that are also part of the nervous system, including the retina and optic nerve.
Neuro-Ocular System
A chromosome band present on 5q
5q35.1-qter
7p14-p13
A chromosome band present on 7p
A chromosome band present on 1q
1q22
Physical location of FAP_Gene
2: 162925552-162852709
Physical location of CREBL2_Gene
12: 12656098-12689308
5: 162820241-162851525
Physical location of HMMR_Gene
A chromosome band present on 3p
3p25.3
A chromosome band present on 7q
7q36
Gallbladder Neck
Round Ligament of the Uterus
Fibrous Astrocyte
A neuroglial cell of ectodermic origin having long, thin, infrequently branched cytoplasmic processes containing numerous fibrillar structures. It is found mainly in the white matter of the brain.
Facial Bone
Any bone that contributes to the facial structures, except those bones that are part of the braincase.
Bone of Face
Fissure of the Ductus Venosus
1q25
A chromosome band present on 1q
2q33-q36
A chromosome band present on 2q
Phagocytic Cell
amebocyte
Phagocytes
Phagocyte
Amygdaloid Nucleus
AMYGDALOID BODY
An almond-shaped group of basal nuclei anterior to the inferior horn of the lateral ventricle of the brain, within the temporal lobe. The amygdala is part of the limbic system. (MeSH)
Amygdala
The area of the spleen through which the vessels and nerves enter or exit the organ.
Splenic Hilum
SPLEEN, HILUM
Splanchnopleure
Palmar Region
A ridge or ridge-like structure. In humans it usually refers to the trachea. The carina of trachea is part of the lowest tracheal cartilage which is placed between the orifices of the two bronchi.
tracheal carina
carina of trachea
Carina, Tracheal
Carina
7q35
A chromosome band present on 7q
External Upper Lip
LIP, UPPER
The external surface of the upper lip.
The fifth lumbar vertebra counting from the top down.
L5 Vertebra
2q33-q37
A chromosome band present on 2q
LeftTesticular Vein
Left Internal Spermatic Vein
Left Spermatic Vein
A chromosome band present on 1p
1p13
7q34
A chromosome band present on 7q
Vessel
Blood Vessel
A tubular structure through which the blood circulates in the body. Blood vessels constitute a network composed of arteries, arterioles, capillaries, venules, and veins.
Physical location of CDKN2C_Gene
1: 51146388-51152327
Lamina Densa
A chromosome band present on 6q
6q24-q25.1
A simple layer of cells, derived from the mesoderm that lines the coelom or body cavity of the embryo. In the adult, it covers all true serous membranes (peritoneum, pericardium, pleura).
Mesothelium
Olfactory Receptor Neurons
Neurons in the olfactory epithelium with receptors that bind, and thus detect, odorants. Unlike other neurons, they can be generated from precursor cells in adults. (MeSH)
Olfactory Receptor Neuron
Visceral Striated Muscle Tissue
Muscle tissue associated with organs such as tongue, pharynx, diaphragm and upper part of the esophagus. It is identical in structure to skeletal muscle tissue.
A chromosome band present on 7q
7q22.1
4q21.3
A chromosome band present on 4q
PA700 Regulatory Module
Ubiquitinated proteins are degraded by a 26S ATP-dependent protease complex, composed of a 20S catalytic proteasome and two 19S PA700 regulatory modules. The multi-subunit PA700 complex binds two sites of the 20S proteasome and is composed of at least six related ATPases and approximately fifteen non-ATPase polypeptides. Each of the ATPases, PSMC1-6, contains an AAA (ATPases associated with diverse cellular activities) domain. A protein complex containing p42 and p50 enhances PA700 activation of the proteasome.
19S Proteasome Regulatory Particle
PA700 Protein
PA700 Protein Complex
19S Regulatory Particle
Physical location of DR1_Gene
1: 93523499-93540170
Tonsillar Lymphoid Tissue
Lymphoid tissue of the tonsils. It is composed of B and T lymphocytes. Lymphoid follicles with germinal centers occupy the areas that are populated with B lymphocytes.
Sinus, Ethmoid
Ethmoid Sinus
A sinus of the meatuses of the nasal cavity.
White Fiber
Physical location of Link-GEFII_plus_H1171Gene
17: 35591394-35605426
10: 123347907-123227846
Physical location of FGFR2_Gene
A chromosome band present on 4q
4q21.2
Microsatellite repeats that have been used as markers of microsatellite instability. BAT26, a poly(A) tract in MSH2 intron 5, is one example of a BAT locus. Presence of alterations in the BAT26 locus, detected in stool samples, may be an easy and non-invasive detection method for colorectal cancer.
BAT Locus
BAT Loci
Serratus Magnus
8: 67253252-67251173
Physical location of CRH_Gene
Connecting Stalk
Supporting Cell of Organ of Corti
Labyrinth Supporting Cells
Labyrinth Supporting Cell
Cells forming a framework supporting the organ of Corti. Specific cells are those of Claudius, Deiters and Hensen. (MeSH)
A hammer-shaped bone, part of three interconnected small bones located in the middle ear. It is attached to the inner surface of the tympanic membrane and its function is to transmit sound vibrations.
Malleus
A chromosome band present on 5p
5p13-p12
Used with tissues and cells (including neoplasms) and microorganisms for microanatomic structures, generally below the size visible by light microscopy.
Intracellular Structure
Subcellular Structure
4: 7607708-76028627
Physical location of BTC_Gene
4q21.1
A chromosome band present on 4q
The lowest part of the prostate gland adjacent to the superior fascia of the urogenital diaphragm.
Apex of Human Prostate
Apical Prostate
Apex of the Prostate
The cortical cell layer of the cerebellum. It consists of the granular layer, molecular layer, and Purkinje cell layer.
Cortical Cell Layer of the Cerebellum
Cerebellum
BRAIN, CEREBELLUM
Cerebellar
20q11.1-11.23
A chromosome band present on 20q
A chromosome band present on 3q
3q26.3-q27
Mechanoreceptor
Mechanoreceptors
Intrathecal Space
Intrathecal
Bladder Mucosa
A chromosome band present on 5p
5p13-p11
5q31-q32
A chromosome band present on 5q
The angled junction where the diaphragm meets the chest wall.
Costophrenic Angle
Stratum Granulosum
Granular Layer
Splenic Arteriole
The free part of the epithelium that faces the exterior surface or the lumen of an organ. It may contain cytoplasmic processes (microvilli, stereocilia, and cilia).
Free Surface of Epithelium
Free Surface of the Epithelium
Apical Domain of Epithelium
Apical Domain of the Epithelium
Oropharynx Epithelium
Optic Groove
Dermal Papilla
A projection of the dermis into the epidermis.
Cervical Gland Secretion
Intrinsic Tongue Muscle Transverse Component
A chromosome band present on 13q
13q14.2-q14.3
7: 91214843-91384640
Physical location of AKAP9_Gene
Left Cerebral Hemisphere
Left Brain Hemisphere
Piriform Recess
Piriform Sinus
Pyriform Sinus
A pear-shaped fossa in the wall of the laryngeal pharynx lateral to the arytenoid cartilage and medial to the lamina of the thyroid cartilage.
A cell situated on one of three of the most outer layers of the basilar membrane of the cochlea. Each cell has multiple, sensitive strands called stereocilia. In the resting state the stereocilia are leaning on each other in a conical bundle and are embedded in the tectorial membrane. When the cochlea moves in response to sound, a slight shearing force occurs between the basilar and tectorial membranes, the stereocilia bend and send electrical impulses to the brain via the eighth cranial nerve.
Outer Hair Cell of Organ of Corti
Outer Hair Cell of the Organ of the Corti
Effector Cell
Epigastric Artery
A chromosome band present on 18p
18p11.31-p11.21
LYMPH NODE, TRACHEOBRONCHIAL
Tracheobronchial Lymph Node
A lymph node located near the bifurcation of the trachea.
Physical location of LGALS3BP_Gene
17: 74487656-74478932
Anterior Inferior Frontal Convolution
The orbital part of the inferior frontal convolution.
Pars Orbitalis
A cell derived from a myeloid stem cell. It is the representation of one stage of monocyte development.
Immature Monocyte
Renal Cell
A glandular epithelial cell found in the kidney.
Retinal Artery
Thyrotroph Cell
Thyrotrope Cell
Thyrotroph
9p21-p22
A chromosome band present on 9p
Pluripotent Stem Cell
A cell that can differentiate to cells derived from any of the three germ layers. --2005
Subareolar Region
The terminal section of the alimentary canal, which extends from the anorectal junction and ends at the anal opening.
Anal Canal
A rounded dilation or expansion in a canal, vessel, or organ.
Bulbar
Bulb
A chromosome band present on 6p
6p21.1-p12.2
A large vein which returns blood from the head, neck and extremities to the heart.
VEIN, VENA CAVA
Vena Cava
16q21-q22.3
A chromosome band present on 16q
Minisatellites
VNTR
Minisatellite
Tandem arrays of moderately repetitive (5-50 repeats) short (10-60 bases) DNA sequences found dispersed throughout the genome and clustered near telomeres. Their degree of repetition is two to several hundred at each locus. Loci number in the thousands but each locus shows a distinctive repeat unit.
Minisatellite Repeats
Minisatellite Repeat
Variable Number Tandem Repeat
Variable Number of Tandem Repeats
17q21.1
A chromosome band present on 17q
Couinaud Liver Segment
Couinaud Segment
Any of the eight liver segments that has its own vascular inflow, outflow, and biliary drainage, thus defined as functionally independent.
A synapse in which an action potential causes the exocytosis of neurotransmitter from the presynaptic cell, which diffuses across the synaptic cleft and binds to ligand gated ion channels on the post synaptic cell. These ion channels then affect the resting potential of the post synaptic cell.
Chemical Synapse
Physical location of AR_Gene
X: 66546895-66727140
Parasympathetic Ganglion
Paraxial Mesoderm
Couinaud Segment II
Left Posterolateral Segment
Couinaud segment II, corresponding to the lateral segment of the left lobe of the liver, located to the left of the superior portion of the falciform ligament and the fissure for the ligamentum venosum.
Foot Digit 3 Phalanx
5q35.2
A chromosome band present on 5q
Cerebral Falx
Falx of Cerebrum
Falx Cerebri
The posterior aspect of the bladder wall.
Posterior Wall of Bladder
Posterior Wall of the Bladder
A chromosome band present on Xq
Xq13.1-q13.3
7: 140077748-139887463
Physical location of BRAF_Gene
Lunula
A relatively thin sheetlike expanse or region lying over or under another.
Layer
Layered
21: 33697072-33731696
Physical location of IFNGR2_Gene
Columnar Epithelium
A chromosome band present on 3p
3p12-q13.2
LARGE INTESTINE, COLON
Colon
The part of the large intestine measured from the cecum to the rectum consisting of ascending, transverse, descending and sigmoid portions. The purpose of the colon is to remove water from digested food prior to excretion.
Physical location of COL1A2_Gene
7: 93668858-93705195
A chromosome band present on 12p
12p13.1-p12.3
Tissue composed of one or more layers of epithelial cells and a basement membrane. It lines the secretory alveoli and secretory ducts of the prostate. The secretory epithelium consists mostly of pseudostratified columnar cells and basal cells with areas of cuboidal and squamous epithelial cells. The walls of the prostatic urethra and the distal regions of the longer ducts are lined with transitional epithelium.
Prostatic Epithelium
Epithelium of Human Prostate Gland
Embryonic Body Cavity
A chromosome band present on 5q
5q35.3
The site at which an antibody makes direct physical contact with a corresponding epitope on an antigen.
Antibody Combining Site
Antibody Binding Site
8: 38153263-38187694
Physical location of BAG4_Gene
Sagittal Sinus
Muscles of facial expression or mimetic muscles that include the numerous muscles supplied by the facial nerve that are attached to and move the skin of the face. (MeSH)
Facial Muscles
Facial Muscle
Esophageal Artery
Chromosome 2 Physical Location
Stratum Germinativum
Rete Malpighii
Endothelium of Fetal Capillary
Endothelium of the Fetal Capillary
Laryngeal Muscle
Tibial Vein
Physical location of FBXW7_Gene
4: 153690635-153601100
Physical location of ANP32C_Gene
4: 165476468-165475764
Visceral Layer of Bowman Capsule
Visceral Layer of Bowman's Capsule
Reticularis Zone
Infraspinatus
Anterior Tibial Vein
The vein that runs parallel to the anterior tibial artery and empties into the popliteal vein.
18: 55718217-55722517
Physical location of PMAIP1_Gene
mesenteric membrane
Mesentery
A double layer of peritoneum that attaches to the back wall of the abdominal cavity and supports the small intestines.
Epithelioid Cell
Characteristic cells of granulomatous hypersensitivity. They appear as large, flattened cells with increased endoplasmic reticulum. They are believed to be activated macrophages that have differentiated as a result of prolonged antigenic stimulation. Further differentiation or fusion of epithelioid cells is thought to produce multinucleated giant cells. (MeSH)
Epithelioid Cells
A chromosome band present on 19q
19q13.13
Lateral Rectus Muscle
Pluripotent Bronchial Precursor Cell
Somatic Cells
Somatic Cell
Auer Body
Auer Rod
Rod-shaped structures of uncertain nature in the cytoplasm of immature myeloid cells, especially myeloblasts, in acute myelocytic leukemia; may be an abnormal form of lysosomes; they contain peroxidase and acid phosphatase, and stain red by azure-eosin stains.
12q23-q24
A chromosome band present on 12q
Sweat Gland Duct
Embryonic Stem Cell
Embryonic stem (ES) cells are cells derived from the inner cell mass of the early embryo that can be propagated indefinitely in the primitive undifferentiated state while remaining pluripotent.
Embryonic Stem Cells
7p14-p12
A chromosome band present on 7p
21: 26465003-26174733
Physical location of APP_Gene
A muscle cell in heart tissue (myocardium).
Cardiocyte
Heart Muscle Cell
Cardiomyocyte
16p13.3-p13.11
A chromosome band present on 16p
12: 101376791-101295444
Physical location of IGF1_Gene
Proximal Enhancer Elements
Proximal Enhancer Element
Enhancer sequences found nearby to the gene it regulates.
Orifice of the Eustachian Tube
Orifice of the Auditory Tube
Orifice of Eustachian Tube
Orifice of Auditory Tube
A cluster of cells that function as chemo-receptors, located at the bifurcation of the carotid artery. Its main purpose is to detect changes in the composition of arterial blood.
Carotid Body
17: 45633992-45616456
Physical location of COL1A1_Gene
Cardia Orifice
Apex of the Pericardium
The part of the pericardial sac that surrounds the great vessels.
Common Iliac Artery Branch
Physical location of GSTM1_Gene
1: 109942484-109948409
Embryonic Tissue
Secondary Chorionic Villus
Gastric Serosal Surface
Tongue Epithelium
Orbit Disc
Physical location of GC_Gene
4: 73014923-72972448
A rod shaped cytoplasmic organelle found in Langerhans cells of the epidermis.
Birbeck Granule
Glycogen Inclusion
A stainable aggregation of glycogen in the cytoplasm.
Distal Part of the Lumen of the Centriole
A portion of the interior of the centriole that is located near the plus ends of the microtubules.
Anything relevant to all anatomic sites - non-specific.
All Sites
2: 100179488-99626334
Physical location of LAF4_Gene
Tooth Part
Any part of a tooth.
Uterine Ligament
Physical location of ERCC1_Gene
19: 50619017-50604712
Genitalia
The external sex organs.
A natural killer cell, activated by a soluble cytokine released by a lymphocyte in response to an antigen. It is important in immune response.
Lymphokine-Activated Natural Killer Cell
Ventroposterior Medial Nucleus of the Thalamus
VEIN, PULMONARY
One of four veins that carries oxygen-rich blood from the lungs to the cardiac left atrium.
Pulmonary Vein
15q23-q24
A chromosome band present on 15q
Minus End of the Actin Filament
The end of an actin filament that is polymerizing at a slower rate.
Pointed End of Actin Filament
Minus End of Actin Filament
Pointed End of the Actin Filament
Macula
A Substrate Domain is a protein region that physically interacts stereospecifically, and usually at high affinity, with a specific target substrate. In enzymes, the substrate domain is often, though not necessarily, coincident with the catalytic domain. Typically, substrate interaction results in some protein conformational alteration and functional modification. (NCI)
Substrate Domain
11: 33870412-33836701
Physical location of LMO2_Gene
14q12
A chromosome band present on 14q
T-Lymphocyte with a Post-Thymic Immunophenotype
Inferior External Articular Artery
Nervous System Part
Presynaptic Terminal
Synaptic Bouton
Presynaptic Knob
An area at the end of an axon that contains neurotransmitters in synaptic vesicles.
Epithelium composed of a single layer of cells attached to a basement membrane.
Simple Epithelium
2: 219570760-219584156
Physical location of WNT10A_Gene
Root of the Nail
Ankyrin Repeats are tandem modules of about 33 amino acids. The conserved domain structure has been described as side-by-side anti-parallel alpha helices connected by intervening beta hairpin motifs or as beta, alpha, alpha, beta secondary structures or as an L-shaped beta-hairpin and two alpha-helices. The repeats associate to form a higher order structure. Despite sequence variation, the domain core maintains a stable surface of contact residues to mediate protein-protein interactions. Target protein binding involves contacts by the beta hairpin tips and the helical bundle surface facing the Ankyrin groove. ANK repeats have been identified in over 1700 functionally diverse proteins, primarily from eukaryotes; no common theme among the protein targets has been identified. The Ankyrin cytoskeletal protein is composed almost entirely of these repeats.
ANK Repeat
ANK Domain
Ankyrin Repeat Domain
Ankyrin Repeat
14q13
A chromosome band present on 14q
Hair Bulb
The lower segment of the hair that circles the dermal papilla and the hair matrix.
Autologous Lymphocytes
Autologous Lymphocyte
17p13.3
A chromosome band present on 17p
Primary Oocyte
The primitive differentiated female gamete which gives rise to an oocyte. (MeSH)
Oogonium
Oogonia
Primordial ovum
Fissure of the Inferior Vena Cava
SITE, INJECTION
The anatomic site at which a medication or a vaccine is injected.
Injection Site
Distal (long) arm of chromosome 14
14q
Chromosome 14 Long Arm
Chromosome 14 Distal Arm
Chromosome 14q
Endothelial Cells
Endotheliocyte
The main type of cell forming the lining of blood and lymph vessels and the inner layer of the endocardium.
Endothelial Cell
Capillary
Tiny blood vessels that connect the arterioles with the venules.
Physical location of GTF2F2_Gene
13: 44592672-44756237
A chromosome band present on 11p
11p15.5-p15.4
Otic Vesicle
A chromosome band present on 17p
17p13.2
Anterior Cranial Fossa
The internal area of the skull that holds the frontal lobes.
Renal Pelvis Transitional Epithelium
Renal Pelvis Urothelium
Remnants of the Central Canal of the Spinal Cord
A solid strand of modified ependyma left from embryonic development of the neural tube.
One of the two bean-shaped organs located on each side of the spine in the retroperitoneum. The right kidney is located below the liver and the left kidney below the diaphragm. The kidneys filter and secret the metabolic products and minerals from the blood, thus maintaining the homeostasis. On the superior pole of each kidney there is an adrenal gland. Each kidney and adrenal gland is surrounded by fat.
Kidneys
Urinary System, Kidney
Kidney
A chromosome band present on 1p
1p36.2-p36.12
A lymph node located in the superior mediastinum that collects lymph from the thymus, the pericardium, and the right side of the heart.
Anterior Mediastinal Lymph Node
10q24.31
A chromosome band present on 10q
Chromosome 14 Proximal Arm
Chromosome 14 Short Arm
Chromosome 14p
14p
Proximal (short) arm of chromosome 14
Hypophyseal Pouch
Rathke Pouch
Rathke's Pouch
Rathke's Diverticulum
A tubular outgrowth of ectoderm from the stomodeum of the embryo; it grows dorsad toward the infundibular process of the diencephalon, around which it forms a cup-like mass, giving rise to the pars distalis and pars juxtaneuralis of the hypophysis.
Pituitary Diverticulum
Rathke's Pocket
Craniopharyngeal Canal
6: 26646551-26655144
Physical location of HMGN4_Gene
11p11.2
A chromosome band present on 11p
Metanephros
Primordium of Permanent Kidney
A chromosome band present on 17p
17p13.1
Embryonic Urogenital System
Heart Atrium
The paired upper chambers of the heart. The left atrium receives oxygenated blood from the pulmonary vein and pumps blood into the left ventricle. The right atrium receives venous deoxygenated blood from the entire body via the superior and inferior vena cavae and pumps blood into the right ventricle.
Auricle of Heart
Cardiac Atrium
Heart Atria
HEART, ATRIUM
Atrium of Heart
Cardiac Atria
Atrium
Atria, Cardiac
Atria of Heart
Discontinuous Capillary
Sinusoid
Sinusoidal Capillary
A chromosome band present on 10q.
10q24.32
X: 122719583-122773357
Physical location of BIRC4_Gene
Teres Major Muscle
Superficial Vein of the Hand
Prepuce Epithelium
Endometrial Stroma
Lobule of the Auricle
A ball-and-socket joint at the upper end of the humerus, located at the junction of humerus and scapula.
Shoulder Joint
Secondary Oocyte
A female germ cell in which the first meiotic division is completed. The second meiotic division usually stops short of completion unless fertilization occurs.
Gastroepiploic Artery
Posterior Part of the Ambient Cistern
5q33.3
A chromosome band present on 5q.
An incomplete or c-shaped microtubule that is part of a microtubule doublet in cilia.
B-Microtubule
A chromosome band present on 2p
2p13-p12
Hand Digit 1 Phalanx
Some isozymes of protein kinase C (PKC) contain a domain, known as C2, of about 116 amino-acid residues which is located between the two copies of the C1 domain (that bind phorbol esters and diacylglycerol) and the protein kinase catalytic domain. Regions with significant homology to the C2-domain have been found in many proteins. The C2 domain is thought to be involved in calcium-dependent phospholipid binding. Since domains related to the C2 domain are also found in proteins that do not bind calcium, other putative functions for the C2 domain such as binding to inositol-1,3,4,5-tetraphosphate have been suggested. The 3D structure of the C2 domain of synaptotagmin has been reported, the domain forms an eight-stranded sandwich constructed around a conserved 4-stranded motif, designated a C2 key. Calcium binds in a cup-shaped depression formed by the N- and C-terminal loops of the C2-key motif. (From Pfam 00168)
C2 Domain
TRAF Motif
TNF Receptor-Associated Factor Motif
TRAF Domain
The TRAF domain is the portion of TRAF family adaptor proteins which bind to TNF receptor cytoplasmic domain. It is the C-terminal homology region of 230 amino acids of signal-transducing proteins associated with members of the TNFR superfamily. This domain is involved in a variety of specific protein-protein interactions.
12p13.1-p12
A chromosome band present on 12p
Embryonic Palate
Physical location of CXCR6_Gene
3: 45959977-45964849
Left Fallopian Tube
Parieto-Occipital Artery
5q33.2
A chromosome band present on 5q
5q35.1
A chromosome band present on 5q
Midgut Loop
The nail at the end of a finger.
Fingernail
Finger Nail
Splenius
Physical location of FRK_Gene
6: 116488614-116369687
Paired glands located on either side of the anus of most carnivores that secrete a noxious-smelling liquid, thus allowing members of the same species to identify one another.
SAC, ANAL
Anal Gland
Thymus Cortex
3: 49686439-49695938
Physical location of APEH_Gene
A chromosome band present on 11p
11p12-p11.2
A chromosome band present on 5q.
5q33.1
Physical location of ING1_Gene
13: 110163084-110171422
Epithelium composed of a single layer of flat cells wider than they are tall. This epithelium is found in anatomic sites where exchange of nutrients, wastes and gases occur.
Simple Squamous Epithelium
Placental Septum
Desidual Septum
21: 33560542-33591390
Physical location of IL10RB_Gene
Aortic Segment
Secretory Cell
One of several types of cells that generate and secrete a substance to be used by the organism.
Chondrification Center
Any of the various aggregations of embryonic mesenchymal cells at sites of future cartilage formation.
A chromosome band present on 14q
14q11
11: 2863551-2861452
Physical location of CDKN1C_Gene
Pleural Mesothelial Cell
Auricular Artery
An artery that supplies oxygenated blood to the ear.
ARTERY, AURICULAR
14: 89155209-88697458
Physical location of CHES1_Gene
Mitral Valve
VALVE, MITRAL
A dual-flap valve of the heart that regulates the flow of blood between the left atrium and the left ventricle of the heart.
Perineuronal Satellite Cell
A flattened non-neuronal cell surrounding a ganglion cell.
Cerebral Hemisphere
CEREBRUM
Cerebral Hemispheres
Brain Hemisphere
Cerebral
One half of the cerebrum, the part of the brain that controls muscle functions and also controls speech, thought, emotions, reading, writing, and learning. The right hemisphere controls the muscles on the left side of the body, and the left hemisphere controls the muscles on the right side of the body.
Multivesicular Body
MVB
A membrane-bound vesicle that encompasses several smaller membrane-bound vesicles.
EBV-specific Cytotoxic T-lymphocytes
Epstein-Barr virus-specific cytotoxic T-lymphocytes
EBV-specific CTL
A white blood cell that is derived from a lymphocyte stem cell matured in the thymus and characterized by a CD8 marker on the surface and an antigen-specific Epstein Barr virus T cell receptor.
EBV-Specific Cytotoxic T-Lymphocyte
Peripheral Blood Mononuclear Cell
PBMC
A monocyte found in the general circulation.
Tyrosine Kinase Domain
A protein domain that binds a protein and catalyzes the covalent addition of a phosphate group specifically to a tyrosine residue.
Opening of the Thorax
A thin layer of tissue that forms the anterior wall of the cochlear duct, which separates it from the vestibular canal.
Membrane of Reissner
Vestibular Membrane
16: 88616509-88638880
Physical location of GAS8_Gene
Fenestra Rotunda
Primordial Optic Nerve
Xp22.1
A chromosome band present on Xp
Physical location of CDK2AP1_Gene
12: 122281567-122270422
Posterior Tibial Artery
Cardiac Vein
T3 Vertebra
The third thoracic vertebra counting from the top down.
Visual Receptor
Photoreceptors
Photosensitive Cell
Photoreceptor
Photoreceptor Cell
Cells specialized to detect and transduce light. (MeSH)
LYMPH NODE, LUMBAR
Lymph Node, Para-Aortic
Paraaortic Lymph Node
A lymph node located adjacent to the lumbar region of the spine.
Golgi Apparatus
Golgi
Golgi Complex
A stack of flattened vesicles located between the nucleus and the secretory pole or surface of a cell. Functions in posttranslational processing and sorting of proteins, receiving them from the rough endoplasmic reticulum and directing them to secretory vesicles, lysosomes, or the cell membrane. The movement of proteins takes place by transfer vesicles that bud off from the rough endoplasmic reticulum or golgi apparatus and fuse with the golgi, lysosomes or cell membrane.
Sister chromatids are the two newly synthesized daughter chromatids derived from the same chromosome parent. During chromosomal pairing in meiosis, recombination occurs exclusively between non-sister chromatids.
Sister Chromatid
Right Lung Bronchiole
Meniscus Lateralis
A semicircular meniscus located towards the outer aspect of the knee joint.
Lateral Meniscus
MENISCUS, LATERAL
Glomerular Capillary
Spinal Cord Arachnoid Membrane
A chromosome band present on Xp
Xp22.2
A chromosome band present on 2p
2p12-p13
Sphenomaxillary Fossa
16: 64958064-64996190
Physical location of CDH5_Gene
1p35.2
A chromosome band present on 1p
Semispinalis Cervicis
8: 143996261-143988977
Physical location of CYP11B2_Gene
3: 4510137-4864081
Physical location of ITPR1_Gene
SH3-Binding Domain
SH3-Binding Motif
Typically found in proteins involved in signaling pathways, the SH3-Binding Motif is a peptide sequence that mediates regulated high-affinity physical interaction (binding) with the SH3 (SRC Homology 3) domain in target protein partners. The SH3-binding motif often share proline-rich stretches containing a common PXXP motif. (NCI)
Hepatic Sinusoid
Desmosomes are intercellular anchoring junctions that anchor intermediate filaments at membrane-associated plaques in adjoining cells. Desmosomes assemble in response to cell-cell contact and raised levels of extracellular calcium. Sensitivity to calcium levels is lost as desmosomes mature.
Desmosome
Desmosomes
Macula Adherens
Spot Desmosome
Activated B-Lymphocyte
A white blood cell produced in the bone marrow that, due to contact with an antigen, able to proliferate and differentiate into B memory cells, antibody-secreting B-lymphocytes or plasma cells.
A chromosome band present on Xp
Xp22.3
Pharyngeal Apparatus
Tooth Cusp
A raised area of the biting surface of a tooth.
Primitive Pit
Left Adrenal Gland
Ocular Conjunctiva
The part of the conjunctiva, a thin transparent mucous membrane, that is loosely attached the orbital septum and covers the anterior surface of the sclera.
Bulbar Conjunctiva
19: 46883936-46869075
Physical location of CEACAM7_Gene
Glycocalyx
An extracellular coating of polymeric sugars or glycoproteins.
11p15.2-p14.3
A chromosome band present on 11p
2: 218857222-218853076
Physical location of IL8RA_Gene
Neurilemmal Cell
Neurilemma Cell
Schwann Cells
Schwann Cell
Neuroglial cells of the peripheral nervous system which form the insulating myelin sheaths of peripheral axons.
14: 103098383-103093192
Physical location of BAG5_Gene
Peyer's Patches
PEYER'S PATCH
Peyer Patch
Lymphoid cell tissue in the small intestinal mucosa.
Membranous
A thin sheet or layer of pliable tissue, serving as a covering or envelope of a part, as the lining of a cavity, as a partition or septum, or to connect two structures.
Membrane
Pericardiac Artery
5: 132327181-132244244
Physical location of AF5Q31_Gene
HEART, RIGHT VENTRICLE
The lower chamber of the heart located in the right side. It receives blood from the right atrium that is no longer oxygenated and it pumps it to the pulmonary artery.
Right Ventricle
Respiratory Primordium
Physical location of DLEU1_Gene
13: 49554308-49577434
Pronephros
A chromosome band present on 5p
5p13.1
Foot Interosseous Muscle
Dermatome
The area of skin innervated by a single posterior spinal nerve (sensory nerve).
Physical location of ERBB2IP_Gene
5: 65258140-65412100
Physical location of CD8B1_Gene
2: 87000696-86954120
17q11-q12
A chromosome band present on 17q
20q12-q13.1
A chromosome band present on 20q
PALATE, SOFT
Soft Palate
A movable fold suspended from the posterior border of the hard palate. (MeSH)
Physical location of CYP7A1_Gene
8: 59575275-59565292
Valve of Vieussens
A chromosome band present on 13q
13q12-13
7: 91520065-91472934
Physical location of CCM1_Gene
Physical location of GUCY1A3_Gene
4: 156945483-157009387
5p13.2
A chromosome band present on 5p
A nephrogenic rest found at the periphery of the renal lobe.
Perilobar Nephrogenic Rest
Chromosome 17 Physical Location
A class of tough protein filaments (including keratin filaments, neurofilaments, desmin, and vimentin) that measure 8-10 nm in thickness and comprise part of the cytoskeleton of the cytoplasm of most eukaryotic cells; so named because they are intermediate in thickness between actin filaments and microtubules.
Intermediate Filament
Esophageal Serosal Surface
Plasma
Plasma is the fluid (noncellular) portion of the circulating blood, as distinguished from the serum that is the fluid portion of the blood obtained by removal of the fibrin clot and blood cells after coagulation.
Superior Occipital Convolution
Physical location of FRAP1_Gene
1: 11256832-11100858
A chromosome band present on Xp.
Xp22.2-22.1
5q22.3
A chromosome band present on 5q
7q21
A chromosome band present on 7q
1: 52394062-52524379
Physical location of MADHIP_Gene
5p13.3
A chromosome band present on 5p
Laryngeal Ligament
The amino acids and their 3-D arrangement in constituting a protein.
Protein Structure
Bladder Serosal Surface
A chromosome band present on 1p
1p35.3
Lumen
Prostate Capsule
Capsule of the Prostate
Capsule of Human Prostate
The membrane the surrounds the prostate gland.
Quadrigeminal Artery
Metatarsal Artery
A chromosome band present on 15q
15q23-q25
Choristoma
Proliferation of normal tissue in an anatomic site in which this particular type of tissue is not normally present.
Breast Duct
milk duct
Hair Cells, Vestibular
Equilibrium Hair Cell
Mechanoreceptors located in the acoustic maculae and the semicircular canals that mediate the sense of balance, movement, and head position. The vestibular hair cells are connected to accessory structures in such a way that movements of the head displace their stereocilia. This influences the membrane potential of the cells which relay information about movements via the vestibular part of the vestibulocochlear nerve to the brain stem. (MeSH)
Vestibular Hair Cell
Interdigitating Dendritic Cell
A dendritic cell found in the paracortex that captures blood-borne antigens in peripheral tissues and transports them to the periarteriolar lymphoid sheath where initial B and T cell activation takes place. These cells play an important role in cellular immunity.
Interdigitating Cells
MAIN BRONCHUS, LEFT
One of the two main bronchi. It is narrower but longer than the right main bronchus and connects to the left lung.
Left Main Bronchus
Long Bone Epiphysis
20q12-q13.2
A chromosome band present on 20q
17: 40192094-40213504
Physical location of ADAM11_Gene
3p
Chromosome 3 Short Arm
Chromosome 3 Proximal Arm
Chromosome 3p
Proximal (short) arm of chromosome 3
Medial Femoral Vein
The cell of the tooth. It includes the odontoblast, cementoblast, cementocyte, and ameloblast.
Tooth Cell
An enzyme producing region of the pancreatic tissue containing the pancreatic acini and exocrine intralobular ducts which collectively secrete the digestive enzymes into the main pancreatic duct to drain into the duodenal part of the small intestine.
PANCREAS, EXOCRINE
Exocrine Pancreas
Ovarian Artery
Microvascular Bed
Microcirculatory Bed
Fetus
Fetal
An unborn or unhatched vertebrate in the later stages of development showing the main recognizable features of the mature being.
1p31.3-p31.2
A chromosome band present on 1p
A chromosome band present on 10p
10p11.1
Orbital Ridge
The bony elevation located beneath the eyebrow.
Anterior Surface of the Stomach
The anterior aspect of the stomach.
2q12.3
A chromosome band present on 2q
Chromosome 3 Long Arm
Chromosome 3 Distal Arm
Distal (long) arm of chromosome 3
3q
Physical location of EPS15_Gene
1: 51697016-51532920
10p11.2
A chromosome band present on 10p
17q23.2-q25.3
A chromosome band present on 17q
Renal Corpuscle
7: 2657200-2540984
Physical location of GNA12_Gene
A chromosome band present on 7q
7q22
Cortical Arch
A chromosome band present on 1p
1p22.1
The more readily stainable portion of the cell nucleus, forming a network of nuclear fibrils within the achromatin of a cell. It is a deoxyribonucleic acid attached to a protein (primarily histone) structure base and is the carrier of genes in inheritance. It occurs in two states, euchromatin and heterochromatin, with different staining properties, and during cell division, it coils and folds to form the chromosomes.
Chromatin Structure
Secondary Brain Vesicle
Physical location of FLT3LG_Gene
19: 54669298-54681300
Cervix Squamous Epithelium
The inferior portion of the urinary bladder which is formed as the walls of the bladder converge and become contiguous with the proximal urethra.
Neck of the Bladder
Cervix Vesicae
Neck of Bladder
BLADDER, NECK
Bladder Neck
16: 67328696-67426945
Physical location of CDH1_Gene
4: 110982233-110967389
Physical location of CASP6_Gene
A chromosome band present on 12q
12q14.3
Central Vein
Collagen Fiber
Collagen Fibril
Body Surface
The surface of an external body region.
Longitudinal Fissure of the Cerebrum
Longitudinal Fissure
Cricoarytenoid Muscle
Primordium
Canal of Tooth
Tooth Canal
The anatomic space in the root of a tooth that contains nerves, blood vessels, and connective tissue.
A chromosome band present on 2q
2q12.2
Physical location of FZD7_Gene
2: 202724816-202728666
1: 117009144-117023893
Physical location of CD2_Gene
Bronchial Secretion
Substantia Propria
Tenon's Capsule
Sclera Proper
Scaphoid Bone
Os Scaphoideum
Scaphoid
Navicular Bone of Hand
A nut-shaped bone of the wrist located in the radial site of the hand. It is one of the eight carpal bones.
Any of the ducts conveying bile between the liver and the intestine, including hepatic, cystic, and common bile duct.
Bile Duct
Cyclic AMP Response Element
CRE
cAMP Response Element
A promoter sequence which interacts with CRE binding proteins to modulate gene expression in response to the level of cAMP in the cell.
DNA Structure
The structure of a DNA molecule, consisting of its primary nucleotide sequence as well as its secondary and tertiary arrangement in space.
Physical location of CYP2C18_Gene
10: 9643368-96485514
Descending Aorta
Physical location of CXCL1_Gene
4: 75100144-75101988
Nail
The cutaneous plate on the dorsal surface of the distal end of a finger or toe.
An mature centriole or basal body.
Mature Centriole
5q21-q22
A chromosome band present on 5q
17q11.2-q21.1
A chromosome band present on 17q
T-Lymphocytes, Helper
Helper T-Cells
Helper Cells
Inducer Cells
T-Lymphocyte, Helper-Inducer
T-Cells, Helper-Inducer
T-Lymphocytes, Inducer
helper T cell
Helper-Inducer T-Lymphocyte
T-Lymphocytes, Helper-Inducer
A subpopulation of CD4+ lymphocytes that cooperate with other lymphocytes (either T or B) to initiate a variety of immune functions. (MeSH)
Parenchyma
The tissue that constitutes the essential part of an organ as contrasted with e.g., connective tissue and blood vessels.
Muscle Fibers
Skeletal Muscle Cell
Rhabdomyocyte
Large single cells, either cylindrical or prismatic in shape, that form the basic unit of muscle tissue. They consist of a soft contractile substance enclosed in a tubular sheath. (MeSH)
Posterior Surface of the Vagina
12q14.1
A chromosome band present on 12q
Optic Vesicle
Inguinal Canal
The oblique anatomic tunnel in the anterior lower abdomen. In males it conveys the spermatic cord structures and is the passage through which the testes descend into the scrotum; in females it conveys the round ligament.
Primordial Phallus
Internal Occipital Vein
Lamina Cinerea
A chromosome band present on 18p
18p11.32
The longitudinal folds present in the upper part of the anal canal.
Anal Column
NBD
The Nucleosomal Binding Domain anchors HMG-14 and HMG-17, two canonical HMG proteins, to nucleosomes. HMG-14 and HMG-17 are the only nuclear proteins known to specifically recognize the genetic structure of the 146-bp nucleosome, i.e., the building block of the chromatin fiber. Although the target of HMG-14/-17 is the nucleosome, the main function of these proteins is to change the architecture of the higher-order chromatin structure. These changes are mediated through the C-terminal region of the proteins. The nucleosomal binding domain anchors these HMG proteins to the nucleosome cores to facilitate HMG-14/-17-dependent changes in chromatin structure.
Nucleosome Binding Domain
17q21.3
A chromosome band present on 17q
A chromosome band present on 1q
1q21-q22
Deep Epigastric Artery
Inferolateral Surface of the Prostate
Inferolateral Surface of Human Prostate
Gingiva
Gingival
gums
Gum
The soft tissue surrounding the neck of individual teeth as well as covering the alveolar bone. The tissue is fibrous and continuous with the periodontal ligament and mucosal covering.
3q22-q24
A chromosome band present on 3q
Capillary Endothelium
Buccal Salivary Gland
Base of the Brain
Base of Brain
17q21.2
A chromosome band present on 17q
1q21-q23
A chromosome band present on 1q
Bone Marrow, Sternal
Bone marrow in the sternum.
Bone Marrow, Sternum
Gastrointestinal Fluid or Secretion
Fluids and secretions within the passage leading from the mouth to the anus through the pharynx, esophagus, stomach, and intestine which cause digestion.
Gastrointestinal Fluids and Secretions
A chromosome band present on 8p
8p23.2-p23.1
Paneth Cell
Epithelial cells found in the basal part of the intestinal glands (crypts of Lieberkuhn). Paneth cells synthesize and secrete lysozyme and cryptdins. (MeSH)
Paneth Cells
7: 142502239-142521622
Physical location of CASP2_Gene
A major stabilizing ligament in the knee that attaches the surfaces of the femur and tibia.
Anterior Cruciate Ligament
Neural Crest
Neurons
Neuron
Neural Cell
Nerve Cells
Neurocyte
Any of the conducting cells of the nervous system. A typical neuron consists of a cell body, containing the nucleus and the surrounding cytoplasm (perikaryon); several short radiating processes (dendrites); and one long process (the axon), which terminates in twiglike branches (telodendrons) and may have branches (collaterals) projecting along its course.
Nerve Unit
Nerve Cell
Physical location of APEXL2_Gene
X: 54909801-54917233
Fibromuscular tissue that separates the thoracic from the abdominal cavity. It increases the volume of the thoracic cavity through contractions, thus facilitating respiration.
MUSCLE, DIAPHRAGM
Diaphragm
Iliothoracic
L2 Vertebra
The second lumbar vertebra counting from the top down.
Physical location of LIFR_Gene
5: 38631253-38515662
A chromosome band present on 12p
12pter-p12
Abdominal Aorta Branch
An arterial segment arising from the abdominal aorta that supplies blood to the abdominal organs, other structures, genitalia and the lower limbs. The aortic branches include terminal branches called the common iliac arteries, the celiac artery, the superior mesenteric artery, the inferior mesenteric artery, the renal arteries, the suprarenal arteries, the testicular (internal spermatic) arteries, the ovarian arteries, the inferior phrenic arteries, lumbar arteries and the middle sacral artery.
Precentral Sulcus
1p35
A chromosome band present on 1p
A muscle that arises from the arytenoid cartilage of one side of the larynx and inserts to the arytenoid cartilage of the opposite site.
Arytenoid Muscle
3q21.2
A chromosome band present on 3q
6: 41857025-41865610
Physical location of C6orf49_Gene
Sublingual Artery
Body System, Renal/Urologic
Organ System, Renal/Urologic
Urologic/Renal Body System
urinary
The organs involved in the creation and excretion of urine.
Urinary tract
Renal/Urologic Body System
Urinary System
Renal/Urologic Organ System
Right Kidney
A bean-shaped retroperitoneal organ situated below the diaphragm and posterior to the liver.
Somatosensory Receptor
Nerve endings encased in connective tissue capsules with myelinated or unmyelinated axons.
5q21.3
A chromosome band present on 5q
A chromosome band present on 5q
5q32-33.1
Duct Epithelium
Ductal Epithelium
18q11.2
A chromosome band present on 18q.
Floor
The lower inner surface of an open space or hollow organ.
A chromosome band present on 1p
1p36
Epithelial Cells, Specialized
Specialized Epithelial Cells
Specialized Epithelial Cell
A cell that covers the surface of the body and lines its cavities that has a specific function to perform.
Intestinal Epithelium
Flexure
An angular or rounded shape made by folding.
Obturator Artery
14q13.1
A chromosome band present on 14q
A muscle cell precursor. It is essential for muscle repair.
Myoblast
Heart Septum
The tissue in the heart that separates the two atria (atrial septum) and the two ventricles (ventricular septum).
HEART, SEPTUM
Cardiac Septum
Elastin Fiber
Part of the chromosome bands present on the long (q) arm of chromosome 18.
18q21.32
Physical location of GTF2H1_Gene
11: 18300719-18345153
Pars Interna of the External Acoustic Meatus
Pars Interna
Deltoid
Spiral Tube of Schchowa
3q24-q28
A chromosome band present on 3q
A thin layer of fibrous tissue capable of stretching and contracting. It is part of the tunica media of the blood vessels.
External Elastic Membrane
16q24
A chromosome band present on 16q
A chromosome band present on 1p
1p33
Lymph Node Trabecula
Lymph Node Trabeculae
The supporting and anchoring strand of connective tissue radiating out from the capsule through the interior of the lymph node.
Physical location of HDAC2_Gene
6: 114398967-114368621
7p14.1
A chromosome band present on 7p
18q11.1
A chromosome band present on 18q
Hematopoietic and Lymphoid Cell
One of the cells of the blood, a leukocyte or erythrocyte. SYN blood corpuscle.
18q21.31
A chromosome band present on 18q
Dorsal Region of Foot
Endocrine/Metabolic Body System
Organ System, Endocrine/Metabolic
Metabolic/Endocrine Body System
Collective designation for those tissues capable of secreting hormones.
Hormonal System
Endocrine System
Endocrine system (all sites)
Body System, Endocrine/Metabolic
Endocrine/Metabolic Organ System
Internal Iliac Vein
Hypogastric Vein
Physical location of BLM_Gene
15: 89061606-89159602
Downstream Enhancer
An enhancer which is located 3' of the gene it regulates.
Notochordal Canal
Genitourinary System
The body system that includes all organs involved in reproduction and in the formation and voidance of urine.
Urogenital System
Genitourinary Tract
Urogenital Tract
genitourinary
10q24-q25.2
A chromosome band present on 10q
Interstitial space between cells, occupied by fluid as well as amorphous and fibrous substances.
Extracellular Space
Melanoblast
An immature precursor cell that gives rise to a melanocyte.
Chromosome 11 Short Arm
Chromosome 11 Proximal Arm
11p
Proximal (short) arm of chromosome 11
Clivus
The sloping surface from the dorsum sellae to the foramen magnum composed of part of the body of the sphenoid and part of the basal part of the occipital bone.
A chromosome band present on 1p
1p34
Liver Ligament
2: 74693515-74696318
Physical location of DOK1_Gene
B-Lymphocytes
B lymphocyte
B Cell
B-Cells
Bursa-Equivalent Lymphocyte
B-Lymphocyte
B-Cell
B Cells
B Lymphocytes
Bursa-Dependent Lymphocytes
Immunologically important lymphocyte that is not thymus-dependent, is either short-lived and naive or long-lived and of memory phenotype, and resembles the bursa-derived lymphocyte of birds in that it is responsible for the production of immunoglobulins.
Epineurium
The smallest units of living structure capable of independent existence, composed of a membrane-enclosed mass of protoplasm and containing a nucleus or nucleoid.
Cells
Cell Type
Cell
Cellular
Normal Cell
Cell Types
{Cells}
Diaphragma Sellae
Renshaw Cell
An inhibitory interneuron in the ventral horn of gray matter of the spinal cord that is held to be reciprocally innervated with a motoneuron so that nerve impulses received by way of processes of the motoneuron stimulate inhibitory impulses back to the motoneuron along an axon of the internuncial cell.
22q11.2
A chromosome band present on 22q
Claustrum
One of three (Inferior, Middle, Superior) paired bony shelves located within the nasal cavity through which inhaled air is taken into the nasopharynx. It is lined with ciliated, pseudostratified columnar epithelium and functions to humidify, heat, and filter incoming air, as well as protecting the olfactory bulb and sinuses from incorrectly pressurized incoming air.
Nasal Turbinate
A lymphocyte found in the thymus. It is a precursor to a mature T-lymphocyte.
Common Thymocyte
Integumentary System
The enveloping membrane of the body; includes, in addition to the epidermis and dermis, all of the derivatives of the epidermis, e.g., hairs, nails, sudoriferous and sebaceous glands, and mammary glands.
Dermatologic Organ System
Organ System, Dermatologic
Dermatologic Body System
Body System, Dermatologic
Female Prepuce
A fold of skin covering the tip of the clitoris.
Preputium Clitoridis
A chromosome band present on 1p
1p31
Posterior Cerebral Artery Branch
One of the two lower extremities in humans used for locomotion and support.
Leg
The thickened bony structures in the mandible and maxilla that contain the sockets of the teeth.
Alveolar Margin
Alveolar Ridge
A chromosome band present on Yp
Yp11.1-q11.1
Cerebral Artery
Cerebral Arteries
5q33.2-q33.3
A chromosome band present on 5q
A chromosome band present on 16q
16q21
5' Region
Sequences immediately preceding a point of interest.
Upstream Region
5' Flank
Platysma Myoides
Temporal Cortex
Temporal Lobe
Parieto-Occipital Sulcus
N-Glycosylation Site
A glycosylation site is an amino acid residue within a peptide that accepts oligosaccharide via amide linkage, specifically through amide nitrogen of asparagine via N-acetylglucosamine, as one of the post-translational modifications.
19: 8023934-8033547
Physical location of CCL25_Gene
A chromosome band present on 10q
10q24.1-q24.3
Precursor T-Lymphoblast
T-Lymphoblast
An immature T-lymphocyte, that has enlarged following stimulation by an antigen, has the capacity to recognize the stimulating antigen and is undergoing proliferation and differentiation either to eliminate the antigen or to a memory state in order to recognize the future appearance of the antigen.
1p32
A chromosome band present on 1p
1: 150351379-150346660
Physical location of S100A2_Gene
Distal (long) arm of chromosome 11
11q
Chromosome 11 Distal Arm
Chromosome 11 Long Arm
Chromosome 11q
Adrenal Medulla
Medullary
Medulla of adrenal gland
The inner part of the adrenal gland; it synthesizes, stores and releases catecholamines. (MeSH)
An epitope composed of adjacent amino acids
Linear Sequence Epitope
Foot Bone
Foot Bones
The tarsus, metatarsus, and phalanges. (MeSH)
Foramen of Luschka
Left Renal Artery
Physical location of KLK15_Gene
19: 56026591-56020357
Common Palmar Digital Artery
The trough in the head of the scapula that receives the head of the humerus to form the shoulder joint.
Glenoid Fossa
Cavity
Body Cavity
A natural hollow or sinus within the body.
Physical location of ITGB4_Gene
17: 71229111-71265494
Physical location of GYPA_Gene
4: 145419449-145388062
A chromosome band present on 14q
14q13.2
The point at which the gingival sulcus terminates because the tissue attaches directly to the tooth.
Bottom of Gingival Sulcus
Enamel
A hard, thin, translucent layer of calcified substance that envelops and protects the dentin of the crown of the tooth. It is the hardest substance in the body and is almost entirely composed of calcium salts.
7: 148019062-147942123
Physical location of EZH2_Gene
Apical Ectodermal Ridge
A thickened surface layer of ectodermal cells found at the end of each limb bud in the developing embryo.
Perinuclear Space
Nuclear Envelope Lumen
Perinuclear Cisterna
Perinuclear Cisternal Space
The area between the inner and outer nuclear membranes that is contiguous with the lumen of the rough endoplasmic reticulum.
Pyloric Orifice
19: 6344184-6330581
Physical location of GTF2F1_Gene
Physical location of TNF_Gene
6: 31651329-31654091
20q13
A chromosome band present on 20q
Arytenoid Cartilage
Either of a pair of small pyramidal laryngeal cartilages that articulate with the lamina of the cricoid cartilage and give attachment to the posterior part of the corresponding vocal ligament and to several muscles.
Osteonal Canal
Haversian Canal
9: 5221419-5223967
Physical location of INSL4_Gene
11: 44543784-44597891
Physical location of KAI1_Gene
Immunoglobulin Hinge Region
A region of relative flexibility between the variable and constant regions of an antibody molecule.
Physical location of IGFBP6_Gene
12: 51777716-51782391
One of eight or ten projections from the dorsum of the tongue forming a row anterior to and parallel with the sulcus terminalis; each papilla is surrounded by a circular trench (fossa) having a slightly raised outer wall (vallum); on the sides of the vallate papilla and the opposed margin of the vallum are numerous taste buds.
Vallate Papilla
Circumvallate Papilla
Postero-Lateral Fissure of the Spinal Cord
A chromosome band present on 16q
16q22
18: 55038380-55048983
Physical location of GRP_Gene
Olfactory Sulcus
20q12
A chromosome band present on 20q
14q13.3
Part of the chromosome bands present on the long (q) arm of chromosome 14.
Canal of Schlemm
Postgerminal Center B-Lymphocyte
The primordial organ in an embryo before its differentiation into testis or ovary.
Indifferent Gonad
2: 217385777-217362335
Physical location of IGFBP5_Gene
14: 63830831-63769608
Physical location of ESR2_Gene
1q22-q25
A chromosome band present on 1q
2: 102066824-102103403
Physical location of IL1R2_Gene
Intermembrane Space of the Mitochondrion
The space between the outer membrane and the inner membrane of the mitochondrion.
Intermembrane Space
Physical location of FGF21_Gene
19: 53951306-53953289
A chromosome band present on 16p
16p12
Cells which secrete an extracellular matrix into which hydroxyapaetite crystals are deposited to form bone.
Osteoblasts
Osteoblast
Papilla of the Tongue
Sacral Spinal Nerve Roots
Sacral Spinal Nerve Root
Mesenchymal Stem Cell
Tunica Vaginalis
Vena Cephalica
Serous membrane that covers the testicles.
Juxtaglomerular Cell
Any of a group of cells that are situated in the wall of each afferent arteriole of a kidney glomerulus near its point of entry adjacent to a macula densa and that produce and secrete renin.
Hypophyseal Portal Vein
The nervous tissue found in that part of the central nervous system that is lodged in the vertebral canal. It contains fewer myelinated fibers, but more nerve cell bodies, unmyelinated nerve fibers and blood vessels than the white matter.
Gray Matter of the Spinal Cord
16p11
A chromosome band present on 16p
Physical location of BMP2_Gene
20: 6697207-6707769
Satellite Cell
An elongated cell that is closely associated with a muscle fiber; it either is flattened against the fiber or occupies shallow depressions in its surface.
A fluid cytoplasmic substance filling the interstices of the cytoskeleton.
Cytoplasmic Matrix
Cell Matrix
Ground Substance Cytosol
Cytomatrix
Ground Substance
Posterior Tooth
Refers to teeth and tissues towards the back of the mouth (distal to the canines): maxillary and mandibular premolars and molars. The designation of permanent posterior teeth in the Universal tooth numbering system include teeth 1 through 5 and 12 through 16 (maxillary), and 17 through 21 and 28 through 32 (mandibular); primary teeth in the Universal tooth numbering system are designated A, B, I, and J (maxillary) and K, L, S, and T (mandibular).
3: 41216004-41256938
Physical location of CTNNB1_Gene
Crus Helicis
Physical location of HDAC5_Gene
17: 39556512-39509647
Allantois
An extraembryonic membrane in the form of a sac. It collects waste from the embryo.
Epidural Space
epidural
Epidural Spinal Canal Space
Space between the dura mater and the walls of the vertebral canal.
The type A domain (vWF) of the von Willebrand factor, a large multimeric glycoprotein found in blood plasma, is the prototype for a protein superfamily. Von Willebrand Factor A Domain is found in various plasma proteins and other extracellular proteins. Although the majority of VWA-containing proteins are extracellular, the most ancient ones present in all eukaryotes are all intracellular proteins involved in functions such as transcription, DNA repair, ribosomal and membrane transport and the proteasome. A common feature appears to be involvement in multiprotein complexes. Proteins that incorporate vWF domains participate in numerous biological events (e.g. cell adhesion, migration, homing, pattern formation, and signal transduction), involving interaction with a large array of ligands. A number of human diseases arise from mutations in VWA domains. (From Interpro IPR002035)
Von Willebrand Factor A Domain
Physical location of MPP1_Gene
X: 153597467-153570672
Physical location of CYP2C19_Gene
10: 96512453-96602661
A chromosome band present on 1q
1q22-q23
Physical location of IRS4_Gene
X: 107785796-107781857
Physical location of IL9_Gene
5: 135259415-135255834
Endocrine Sex Organ
PEBODSYS
Physical Examination Body System or Organ Class
The body system or organ class that pertains to a physical examination.
Longus Capitis
Lymphatic Vessel Endothelium
Capitate Bone
Capitate
The largest of eight carpal bones, located in the center of the hand.
Corneal Endothelium
5p13.1-p12
A chromosome band present on 5p
Chorion
The outermost layer of the membranous sac enclosing the embryo in higher vertebrates.
Chorionic
Posterior Auricular Vein
Coronary Vein
Fusiform Cell
A cell with spindle-like morphologic characteristics..
An octagonal opening, about 70 nm across, where the inner and outer membranes of the nuclear envelope are continuous.
Nuclear Pore
8: 144171300-144175199
Physical location of LY6E_Gene
Uncinate Pancreas
Uncinate Process
Uncinate Process of Pancreas
A portion of the pancreas that extends behind the superior mesenteric artery and superior mesenteric vein.
The finest filamentous element of the cytoskeleton, having a diameter of about 5 nm and consisting primarily of actin.
Microfilament
Actin Filament
Epithelium
A chromosome band present on 1q
1q22-q24
Physical location of HM74_Gene
12: 121726224-121724184
A membrane lining the external walls of the body cavities and reflected over the surfaces of protruding organs. It consists of mesothelium lying on a connective tissue layer, and secretes a watery exudate.
Serous Membrane
Serosa
Nucleosomal Repeat Length
Nucleosomal repeat length is approximately 200 base pairs of DNA within which 146 base pairs are highly protected. (NCI)
DUCT, CYSTIC
A short duct attached to the gallbladder through which the bile from the gallbladder is secreted in the common bile duct.
Cystic Duct
Physical location of FLI1_Gene
11: 128069199-128187521
Femoral Vein
VEIN, FEMORAL
A vein that starts within the inguinal region and extends to the lower extremities.
Any portion of a protein molecule with a net negative charge.
Acidic Region
Ear Part
The male organ of urination and copulation.
Genital System, Male, Penis
Penis
Eyelid Subcutaneous Connective Tissue
renal collecting tubule
Straight Tube
collecting duct
Collecting Tube
Nasal Cavity
The proximal portion of the respiratory passages on either side of the nasal septum lying between the floor of the cranium and the roof of the mouth and extending from the face to the pharynx. The nasal cavity is lined with ciliated mucosa, extending from the nares to the pharynx.
BODY CAVITY, NASAL
A chromosome band present on 5q
5q12.1-q13.2
Axilla
The underside concavity where the arm and the shoulder are joined.
Armpit
Underarm
The bodily system of organs and tissues, primarily the bone marrow, spleen, tonsils, and lymph nodes, involved in the production of blood considered together with the interconnected system of spaces and vessels between body tissues and organs by which lymph circulates throughout the body.
Hematopoietic and Lymphatic System
Left Lumbar Region
Tissue characterized by the presence of large numbers of lymphocytes in different stages of transformation. Connective tissue cells including fibroblasts and macrophages may be present. Lymphoid tissue is framed by a network of reticular fibers and may be diffuse, or densely aggregated.
Lymphoid Tissue
The curved cartilage ridge on the flap of the ear that is parallel to the helix.
Antihelix
Stomodeum
Primordial Mouth
Physical location of LCK_Gene
1: 32409019-32420854
Metacarpal Bone Digit 1
A 50-150bp DNA sequence that increases the rate of transcription of coding sequences. It may be located at various distances and in either orientation upstream from, downstream from or within a structural gene. When bound by a specific transcription factor it increases the levels of expression of the gene, but is not sufficient alone to cause expression. Distinguished from a promoter, that is alone sufficient to cause expression of the gene when bound.
Enhancer
7q21.2-q22.1
A chromosome band present on 7q
Fibrous Coat of the Liver
A chromosome band present on 13q
13q14.1-q14.2
4q13.3-q21.1
A chromosome band present on 4q
Arachnoid Villus
Glandulae Pacchioni
Small projection of the arachnoid membrane through the dura into a venous sinus.
5q12-q13
A chromosome band present on 5q
Metacarpal Bone Digit 2
Physical location of CXCR3_Gene
X: 70621388-70618788
Endoderm
Spinal Artery
ARTERY, SPINAL
A branch of the intercostal artery that supplies oxygenated blood to the spinal cord and the pia mater.
Rib 10
The tenth rib counting from the top of the rib cage down.
Autosome
Autosomal
A chromosome not involved in sex determination. The diploid human genome consists of a total of 46 chromosomes which includes 22 pairs of autosomes.
Physical location of LAMP3_Gene
3: 184363325-184322706
Brachial Artery Branch
11: 2139000-2137585
Physical location of INS_Gene
A chromosome band present on 20q
20q12-q13
Breast Lobule
Physical location of AXIN2_Gene
17: 60985289-60956106
Right-Handed Beta-Alpha Superhelix
LRR
Leucine-Rich Repeat
A leucine-rich protein structural motif that forms an alpha/beta horseshoe tertiary structure. It is composed of repeating units of 20-30 amino acid stretches that are rich in leucine residues. This structural motif is found in a wide variety of unrelated proteins.
FSH Cell
A basophilic cell of the anterior pituitary gland whose granules secrete follicle-stimulating hormone
The earliest of four stages in development of the normoblast.
Proerythroblast
Primordial Laryngeal Inlet
Rib 12
The twelfth rib counting from the top of the rib cage down.
Metacarpal Bone Digit 3
Tongue Skeletal Muscle Tissue
Rib 11
The eleventh rib counting from the top of the rib cage down.
Physical location of ERCC2_Gene
19: 50565669-50546686
Physical location of HP_Gene
16: 70646027-70652455
EBV-Transformed Mature B-Lymphocyte
Internal Circumflex Artery
A chromosome band present on 9q
9q34.1
Shoulder
The region of the body between the neck and the upper arm.
Physical location of EIF4EL3_Gene
2: 233240926-233259424
Metacarpal Bone Digit 5
Mesonephric Remnants
Serosal Surface of the Liver
The membrane lining the external surface of the liver.
The organized colloidal complex of organic and inorganic substances (as proteins and water) that constitutes the living nucleus, cytoplasm, plastids, and mitochondria of the cell. It is composed mainly of nucleic acids, proteins, lipids, carbohydrates, and inorganic salts.
Protoplasm
1q23.3
A chromosome band present on 1q
Stapedius Muscle
Stapedius
A chromosome band present on 3p
3p24.1-p22
3q22.3
A chromosome band present on 3q
A chromosome band present on 6p
6p11.1
The pigmented protuberance on the surface of the breast through which milk is drawn from the breast.
Nipple
Physical location of CDC2L1_Gene
1: 1686433-1666482
Glandular Epithelial Tissue
Metacarpal Bone Digit 4
Sulcus Centralis Insulae
Fetal Skeleton
Pectoralis Minor
Musculus Pectoralis Minor
Knee
JOINT, KNEE
Tibiofemoral Joint
A joint connecting the lower part of the femur with the upper part of the tibia. The lower part of the femur and the upper part of the tibia are attached to each other by ligaments. Other structures of the knee joint include the upper part of the fibula, located below and parallel to the tibia, and the patella which moves as the knee bends.
Knee Joint
1q23.2
A chromosome band present on 1q
A chromosome band present on 3q
3q21-qter
A chromosome band present on 9q
9q34.3
11: 117680824-117692096
Physical location of CD3E_Gene
Atrium of the Middle Ear
The irregular lower chamber of the middle ear.
9: 21358075-21357423
Physical location of IFNA13_Gene
The superficial nerve tissue of the spinal cord. It is composed of nerve cell processes, i.e. extensions (axons), which connect various grey matter areas of the spinal cord to each other and carry nerve impulses to and from the nerve cell bodies within the central nervous system (neurons). Spinal white matter does not contain dendrites. White matter is distinguished in that it is composed of axonal nerve fibers covered by a myelin sheath.
White Matter of the Spinal Cord
6p11.2
A chromosome band present on 6p
Physical location of EPHB2_Gene
1: 22782764-22987098
Isomer
A chromosome band present on 11p
11p15.2
Gamma-Tubulin Ring Complex
A complex comprised of gamma tubulin and other proteins that can act as a scaffold for the nucleation of microtubules.
Gamma-TuRC
Splenial Artery
Superior Thyroid Artery
Cuboidal Cell
A cube-shaped epithelial cell. Because a cuboidal cell has a relatively large cytoplasmic volume, it can undertake more complex functions such as absorption and secretion. Most glandular secretory cells are cuboidal epithelial cells and the ducts of most exocrine glands and kidney tubules are lined by cuboidal cells.
Cuboidal Cells
Cementoblast
A large cell ranging in shape from cuboidal to squamous with a large central nucleus. The nucleus usually has a single nucleolus, which is active in the formation of cementum.
A chromosome band present on 1q
1q42.1-q42.2
16: 55553263-55575257
Physical location of CETP_Gene
Hypothalamohypophyseal Portal System
11: 65412586-65407787
Physical location of FIBP_Gene
Esophageal Muscular Coat
Xp11.4-p11.2
A chromosome band present on Xp
Osteoclasts
Osteoclast
A large multinuclear cell associated with the absorption and removal of bone. (MeSH)
Bones of Lower Extremity
Bone of Lower Extremity
A bone of the leg (lower extremity).
Bone of the Lower Extremity
Middle Cerebral Artery
MCA
Middle Cerebral Arteries
A chromosome band present on 11p
11p15.1
Lunate Sulcus
Membrane-Attached Ribosome
A ribosome that is associated with the membrane of the rough endoplasmic reticulum.
Arteriole Endothelium
The layer of cells that line the lumen of an arteriole.
Physical location of FLJ20174_Gene
3: 114734183-114830960
Distal (long) arm of chromosome 6
Chromosome 6 Long Arm
Chromosome 6 Distal Arm
6q
Hematopoietic Stem Cell
Hemocytoblast
Hematohistioblast
Ferrata cell
Hemohistioblast
Progenitor Cells, Hematopoietic
Hematopoietic Progenitor Cells
Hematopoietic Stem Cells
Primitive blood cells derived from embryonic mesenchyme capable of differentiating into any of the blood cell line progenitor cells (erythroblasts, young granulocytic series cells, megakaryocytes, etc.)
Stem Cell
Blood Precursor Cell
Physical location of LOH11CR2A_Gene
11: 123491321-123522829
Temporal Artery
Typically found in SH2-Binding Motifs of signaling proteins, the YXXP Motif interacts with SH2 domains of partner proteins upon Y phosphorylation. SH2 domains of ~100 amino acids bind to specific phosphotyrosine (pY)-containing motifs with dissociation constants of ~50-500 nM. A conserved pocket of SH2 domains recognizes the pY; a more variable pocket binds residues C-terminal to pY that confer specificity. SH2 domains balance high affinity for pY and recognition of adjacent residues to allow specific discrimination. The SH2 domain, an anti-parallel b-sheet between a-helices, provides a positively charged b-sheet pocket for binding of pY moieties, and an extended b-sheet surface for binding residues C-terminal to pY. B-sheet surface differences have significant effects on ligand-specificity. (NCI)
YXXP (tyrosine-X-X-Proline), a substrate sequence preferred by Abl tyrosine kinases, is part of the SH2 domain that mediates certain interactions of SH2 containing proteins. Although both phosphorylated- and unphosphorylated-YXXP can interacts with SH2 containing proteins, the SH2 domain obtain sufficient binding specificity from the recognition of adjacent residues to allow discrimination between different phosphorylated sites. (NCI)
YXXP Domain
YXXP Motif
Nasolacrimal Duct
DUCT, NASOLACRIMAL
Duct, Nasolac
A tube-like structure that conveys tears from the lacrimal sac to the nasal cavity.
16: 55963900-55976457
Physical location of CX3CL1_Gene
Physical location of IL8_Gene
4: 74971310-74974468
Stratum Lucidum
Clear Layer
8p11.2-p11.1
A chromosome band present on 8p
Bronchus Connective Tissue
Myelinated Nerve Fiber
Axons of neurons encased in a lipoproteinaceous material called myelin. (MeSH)
Nerve Fibers, Myelinated
Multiform Cell Layer of the Cerebral Cortex
Multiform Cell Layer
Polymorphic Cell Layer
The innermost layer of the cerebral cortex. It consists of numerous small neurons, small pyramidal cells, stellate cells, especially superficially and fusiform cells in deeper part whose axons project into the white substance of the cerebral cortex hemisphere
The eleventh thoracic vertebra counting from the top down.
T11 Vertebra
Gland of Littre
GLAND, URETHRAL
Periurethral Gland
Urethral Gland
Any of the glands located at the wall of the urethra of male mammals that produce and secrete mucus, a major component of semen.
Any of the molars located in the upper jaw.
Upper Jaw Molar
A chromosome band present on Xq
Xq11.2-q12
PH Domain
Pleckstrin Homology Domain
Pleckstrin-Homology Domain
Pleckstrin-homology (PH) domains are protein modules of approximately 120 amino acids found in a wide variety of signaling proteins in organisms ranging from yeast to humans. Some PH domains bind with high affinity (low mM or nM Kd) to specific phosphoinositides such as phosphatidyl-inositol (PI) -4,5-bisphosphate, PI-3,4-P2 or PI-3,4,5-P3. Binding to phosphoinositides may allow PH proteins to respond to lipid messengers for example by relocation to membranes. The C-termini of some PH domains have also been reported to bind the beta/lambda subunits of heterotrimeric G proteins.
A chromosome band present on 14q
14q32.3
A thin membrane that separates the external auditory canal from the middle ear. The movement of the tympanic membrane in response to air pressure changes in the external ear facilitates the transmission of sound energy by causing vibration of the ossicular chain.
Membrana Tympanica
TM
Tympanic Membrane
Membrane, Tympanic
Eardrum
TM - Tympanic Membrane
Ear Drum
10: 102880252-102887536
Physical location of HOX11_Gene
Fossa
A concavity in a surface, especially an anatomical depression.
Connective tissue with fibrous and cartilaginous components.
Fibrocartilage
Calcarine Artery
A cell that forms the supporting matrix of one of the glands that secretes substances into the blood or lymph.
Endocrine-Stromal Cell
Omental Fat
Omentum
A fold of peritoneum originating at the stomach and supporting the viscera.
T2 Vertebra
The second thoracic vertebra counting from the top down.
13: 27967232-27773790
Physical location of FLT1_Gene
Deep Fascia
The region of the body that includes the arm, the forearm, and hand.
Upper Limb
LIMB, UPPER
FORELIMB
Upper Extremity
A chromosome band present on 14q
14q32.2
Physical location of FGF6_Gene
12: 4425041-4413569
Lumen of the Peroxisome
The area within the membrane of a peroxisome.
A projection or prominence opposite the tragus that is found on the lower exterior portion of the ear.
Antitragus
Visceral Part of the Peritoneum
visceral peritoneum
Hypoglossal Nerve
Twelfth Cranial Nerve
Physical location of GPRK6_Gene
5: 176786389-176802456
Left Ear
The organ of hearing located on the left side of the head.
4q21-q24
A chromosome band present on 4q
Chromosome 6 Proximal Arm
Chromosome 6 Short Arm
6p
Proximal (short) arm of chromosome 6
5: 148910850-148855742
Physical location of CSNK1A1_Gene
Physical location of ADAMTS1_Gene
21: 27239386-27130479
Embryoblast
Inner Cell Mass
Brain, Nervous System
Nervous System, Brain
Brain
An organ composed of grey and white matter containing billions of neurons that is the center for intelligence and reasoning. It is protected by the bony cranium.
Physical location of NFIA_Gene
1: 61260314-61634057
14q32.1
A chromosome band present on 14q
A muscular tube that extends from the end of the small intestine to the anus.
Large Bowel
Large Intestine
17: 64922434-65051067
Physical location of MAP2K6_Gene
BCL-2 Homology 1 Domain
Found in proteins that regulate apoptosis, conserved a-helix BCL-2 Homology (BH1-4) Domains are critical to protein apoptotic function and the protein ability to interact/dimerize with other family members or regulatory proteins. BH1 contains predominantly hydrophobic residues. BCL-2 family proteins dimerize among pro- and anti-apoptotic class family members. BCL-2 homodimerization appears to involve head-to-tail interaction of N-terminal BH4 resides with more distal BH1, BH2, and BH3 regions. BCL-2/BAX heterodimerization appears to involve tail-to-tail interaction of the BCL-2 BH1, BH2, and BH3 regions and the BAX BH3 domain region. BCL-2 may suppress cell death partly by binding to BAX via the BH3 domain preventing BAX homodimer formation. (NCI)
BH1 Domain
Posterior Circulation Intracranial Artery
10p12.31
A chromosome band present on 10p
Gastric Muscular Coat
Gastric Muscularis Externa
A beta strand is an extended polypeptide chain with the sidechains pointing away from the backbone and oriented on opposite sides of the backbone from one residue to another.
B-strand
Beta Strand
A tube-like structure present in the developing embryo that connects the area in which the thyroid gland initially develops, the oropharynx, to the final position of the thyroid gland in the newborn. This structure normally atrophies prior to birth but may persist in some cases.
Thyroglossal Duct
DUCT, THYROGLOSSAL
A type of interneuron that conveys information to the brain.
Ganglion Cells
Ganglion Cell
Visceral Afferent Neuron
A cell that conducts a nerve impulse that originated at a receptor in one of the interior organs of the one of the three cavities of the body and proceeds towards the central nervous system.
17: 38978773-38960740
Physical location of ETV4_Gene
4: 111191654-111291023
Physical location of EGF_Gene
Cellular Matrix
Cytoskeletal System
Cytoskeletal
Cytoskeleton
The protein scaffolding (the network of filaments microfilaments, microtubules, intermediate filaments, and their associated proteins) that gives shape, structure, and organization to the cytoplasm and a cell its shape.
Bronchial Artery
Immature Platelet
A young platelet that contains residual mRNA and rRNA when released from the bone marrow into the peripheral circulation as a result of thrombopoiesis. Immature platelets normally make up a small percentage of the total circulating platelets (1.1-6.1%, with a mean of 3.4%.). An increased proportion of immature platelets in blood indicates increased thrombopoiesis. The relationship between the percent of immature platelets and the platelet count can be used to determine the rate of platelet turnover.
Semimembranosus
Physical location of HMGB1_Gene
13: 29938013-29931997
16: 70600164-70616456
Physical location of DHODH_Gene
17: 31455333-31457127
Physical location of CCL4_Gene
Hepatobiliary Tissue
Upper Opening of the Thorax
Physical location of ADRA2B_Gene
2: 96203762-96200497
19: 7245011-7067638
Physical location of INSR_Gene
Stratum Reticulare
The lymphoid tissue of the thymus in which T cell maturation occurs.
Thymic Lymphoid Tissue
Bromodomain
A motif common in chromatin remodeling factors. It consists of approximately 110 amino acids in a left-handed up-and-down four helix bundle with a left handed twist. A hydrophobic pocket in the bromodomain creates an acetyl-lysine binding domain. Bromodomain-containing proteins may recruit remodeling complexes to acetylated chromatin regions.
Testicular Artery
ARTERY, SPERMATIC
Internal Spermatic Artery
A branch of the abdominal aorta that supplies oxygenated blood to the testis.
Spermatic Artery
A chromosome band present on 10p
10p12.1
Superior Cerebellar Artery
SCA
A chromosome band present on 7q
7q21.3-q22
Chromaffin Cells
Chromaffin Cell
Cells that store epinephrine secretory vesicles. Characteristically, they are located in the adrenal medulla and paraganglia of the sympathetic nervous system. (MeSH)
Odontogenic Epithelium
A reticular epithelial cell generated in the thymus that affects T-lymphocyte cell production. Thymic epithelial cells are organized in a three-dimensional network rather than as a sheet of cells on a basement membrane.
TEC
Thymic Epithelial Cell
Lateral Sulcus of Sylvius
Nasal Cavity and Paranasal Sinus
Transversus Abdominis
Pectoralis Muscle
Muscle, Pectoral
MUSCLE, PECTORALIS
Muscles of the upper chest. The term may refer to one of two muscles, the pectoralis major and pectoralis minor. The former is a thick muscle in the anterior portion of the chest. Its action involves flexion, medial rotation, and adduction of the humerus. The latter is a thin muscle located beneath the pectoralis major. Its action involves lowering the scapula and raising the ribs.
Cells which include the monocytes and the granulocytes.
Myeloid Cells
Myeloid Cell
A group of body parts that work together to perform a given function.
Apparatus
Vocal Cords
Vocal Cord
A pair of small bands of muscle that stretch from the thyroid cartilage in front to the arytenoid cartilage in back of the larynx. The vocal cords help prevent food entering the lungs and produce sound through vibration.
Peripheral Zone of the Prostatic Parenchyma
Prostatic parenchyma that occupies the posterior and lateral aspects of the prostate gland. The glandular architecture consists of small, round acini amid loosely woven, randomly oriented stroma. The peripheral zone contains large, so-called main glands, whose ducts run posteriorly to open into the urethra. Approximately 70% of the prostate gland lies in the peripheral zone.
Adrenal Fluid or Secretion
Adrenal Fluids and Secretions
Adrenal-Fluids, Secretions
Epinephrine and norepinephrine from the medulla and steroid hormones from the cortex.
External Ear Cartilage
Physical location of INHBA_Gene
7: 41513299-41502036
Upper-inner Quadrant of Breast
Upper-Inner Quadrant of the Breast
The quarter of the breast which is superior and medial.
Physical location of GAS2_Gene
11: 22646230-22791123
1: 24817154-24916065
Physical location of CLIC4_Gene
Superior Cerebellar Cistern
Mucosa of Lower Lip
Mucosa of the Lower Lip
The lining of the inferior fleshy fold bordering the mouth. It is comprised of the epithelium, basement membrane, lamina propria mucosae, and lamina muscularis mucosae.
Medial Orbitofrontal Artery
Eparterial Branch of the Right Main Bronchus
Jugular Vein
Vena Jugularis
VEIN, JUGULAR
Veins in the neck which drain the brain, face, and neck into the brachiocephalic or subclavian veins.
Bone marrow in the scapula.
Bone Marrow, Scapula
A chromosome band present on 2p
2p23-p22
Oral Cavity Epithelium
RSXpSXP Domain
RSXpSXP Motif
The 14-3-3 family of proteins mediates signal transduction by binding to phosphoserine-containing proteins. RSXpSXP Motif is one of two different binding motifs that are present in nearly all known 14-3-3 binding proteins. The14-3-3 dimer binds tightly to single molecules containing tandem repeats of phosphoserine motifs, implicating bidentate association as a signaling mechanism with molecules such as Raf, BAD, and Cbl. (from OMIM)
Lacrimal Apparatus
12p12.1-p11.2
A chromosome band present on 12p
Gonadotroph
Gonadotrope Cell
An endocrine cell of the adenohypophysis that affects certain cells of the ovary or testis.
Gonadotroph Cell
Serratus Dorsalis Cranialis
Superior Thoracic Artery
Choroid Plexus of the Fourth Ventricle
Foramen of Magendie
Magendie's Foramen
Femoral Artery
An artery that starts within the inguinal region and extends to the lower extremities.
ARTERY, FEMORAL
An activated lymphocyte with a diameter of about 12 micrometers, a nucleus with deep folds or clefts and clumped chromatin.
Large Cleaved Cell
1: 222319711-222339996
Physical location of EPHX1_Gene
Frontal Bone
Renal Efferent Vessel
Tarsal Plate
ectocervical
Exocervix
Ectocervix
Chorionic Villus
Tiny vascular tissue projections from the membranous sac that surrounds the embryo.
Middle Lobe of the Right Lung
LUNG, RIGHT MIDDLE LOBE
Right Middle Lobe, Lung
Lung Middle Lobe
Middle Lobe of Lung
RML
The smallest lobe of the right lung, situated above the oblique fissure and below the horizontal fissure.
8p22-q11
A chromosome band present on 8p
11: 47247535-47308158
Physical location of MADD_Gene
A part the bronchial tree of the right lung, an air passage arising from any segmental bronchus of the right lung and passing to the naturally delimited part of lung segment (subsegment), where it further subdivides into smaller passages.
Subsegmental Bronchus of Right Lung
A binding site where a ligand is permanently bound.
Nonexchangeable Site
Type II Pneumocyte
A pleomorphic cell of the pulmonary alveolar epithelium that secretes surfactant and is distinguished by abundant cytoplasm containing numerous lipid-rich multilamellar bodies.
Alveolar Cell Type II
A very slender, longitudinal column of motor neurons in the ventrolateral medulla oblongata; its efferent fibres leave with the vagus and glossopharyngeal nerve and innervate the striated muscle fibres of the pharynx (including the musculus levator veli palatini) and the vocal cord muscles of the larynx.
Nucleus Ambiguus
Tissue
An anatomical structure consisting of similarly specialized cells and intercellular matrix, aggregated according to genetically determined spatial relationships, performing a specific function.
Normal Tissue
Tissues
Tissue Types
Physical location of DDR2_Gene
1: 159333918-159481869
Perineurium
A layer of connective tissue surrounding bundles of nerve fibers. It is formed by flattened cells that have a basement membrane on each side.
Tunica Vasculosa
A chromosome band present on 16q
16q12.1
Internal Carotid Nerve Plexus
Nociceptor
Pain Receptor
Nociceptors
A free nerve ending that is a receptor for painful stimuli. (Kanner)
Concha
7p22.2
A chromosome band present on 7p
A lymph node located close to, on, or within the parotid gland.
LYMPH NODE, PAROTID
Parotid Gland Lymph Node
Ileocolic Vein
Inferior Palpebral Vein
A chromosome band present on 1q
1q42.1-q43
Physical location of FURIN_Gene
15: 89212889-89227691
10: 101180336-101146618
Physical location of GOT1_Gene
Primitive Groove
Spinal Cord Fissure
Levator Nasolabialis
Optic Commissure
7: 79920284-79948387
Physical location of CD36_Gene
Pelvis
Pelvic Cavity
Pelvic
BODY CAVITY, PELVIC
The bony, basin-shaped structure formed by the hipbones and the base of the backbone supporting the lower limbs in humans.
17q11-q21.3
A chromosome band present on 17q
A nucleus composed of neurons in the forebrain.
Accumbens Nucleus
16q12.2
A chromosome band present on 16q
A chromosome band present on 7p
7p22.1
Autonomic Ganglia
Autonomic Ganglion
2: 111151853-111111643
Physical location of BUB1_Gene
Fat Cells
Adipocyte
Fat-storing cells found mostly in the abdominal cavity and subcutaneous tissue. (MeSH)
Fat Cell
Mature Lipocyte
Adipocytes
Lipocytes
Mature fat cell
Adipose Cell
17: 31441600-31439716
Physical location of CCL3_Gene
Large Intestinal Crypt of Lieberkuhn
8: 79880313-79807561
Physical location of IL7_Gene
Secondary Palate
Physical location of HLA-A_Gene
6: 30018310-30021042
Metatarsal Bone Digit 3
Pulmonary Artery Branch
11: 127897371-127833873
Physical location of ETS1_Gene
A chromosome band present on 1p
1p21
Decidua Capsularis
A chromosome band present on 17q
17q25.2-q25.3
CEBODSYS
The body system or organ class affected by a clinical event.
Clinical Events Body System or Organ Class
Postcentral Sulcus
Any one of the seven vertebrae that start with C1, connecting the skull to the spine, and ends with C7, which joins the cervical with the thoracic spine.
Cervical Vertebra
Cervical Vertebrae
Early Endosome
The endosomal compartment that fuses with endocytic vesicles and sorts the plasma membrane components from any internalized molecules that are targeted for lysosomal degradation.
Compartment of the Uncoupling Receptors and Ligands
Compartment of Uncoupling Receptors and Ligands
CURL
A centriole-containing organelle that serves as the base and nucleation site for microtubules that form cilia or flagella.
Basal Body
Kinetosome
2p24.3-q21.3
A chromosome band present on 2p
8p23.1-p21.3
A chromosome band present on 8p
Posterior Eye Segment
Right Ureter
Spinal Cord Part
Metatarsal Bone Digit 4
Physical location of XAF1_Gene
17: 6599880-6619690
A chromosome band present on 1p
1p22
14: 74539401-74546045
Physical location of EIF2B2_Gene
Physical location of ELK3_Gene
12: 95090785-95064077
Posterior Wall of the Pharynx
Endomysium
Physical location of CCL3L1_Gene
17: 31649843-31647955
Chromosome 12 Long Arm
Chromosome 12 Distal Arm
12q
Distal (long) arm of chromosome 12
Medial Lenticulostriate Artery
A chromosome band present on 2q
2q14.1
Pelvic Floor Muscle
Superior Profunda Artery
Arteria Profunda Brachii
Metatarsal Bone Digit 1
5: 140996596-140980627
Physical location of HDAC3_Gene
12p
Chromosome 12 Short Arm
Chromosome 12 Proximal Arm
Proximal (short) arm of chromosome 12
Amacrine Cells
Amacrine Cells of Retina
Amacrine Cell
A retinal neuron that lacks large axons, having only processes that resemble dendrites.
The N-terminal sequence of a secreted protein that interacts with a signal recognition particle and is required for transport through the cell membrane.
Signal Peptide
Leader Sequence
Signal Sequence
Musculus Psoas Minor
Psoas Parvus
Psoas Minor
Metatarsal Bone Digit 2
11: 6581588-6588677
Physical location of ILK_Gene
Physical location of S100A9_Gene
1: 150143403-150146572
2q33-q34
A chromosome band present on 2q
Physical location of CDC7_Gene
1: 91678465-91703335
A lymph node at the base of the celiac artery.
Celiac Lymph Node
A network of tubules that convey sperm from the seminiferous tubules within the testicles to the efferent ducts.
Rete Testis
Physical location of FGF3_Gene
11: 69343129-69333917
Odontoblast
A cell derived from a preodontoblast that secretes predentin. Each odontoblast has a cytoplasmic extension, an odontoblastic process that traverses the thickness of the dentin and helps to maintain the dentin.
Odontoblasts
Septal Vein
Bulbus Cordis
14: 104838374-104746670
Physical location of BRF1_Gene
Proctodeum
Anal Pit
Physical location of ARMET_Gene
3: 51397518-51401815
A B-lymphocyte that has been activated to be receptive to Epstein Barr virus and is found in the area of a lymph nodule containing aggregations of actively proliferating lymphocytes.
EBV-Transformed Late Germinal Center/Post-Germinal Center B-Lymphocyte
A chromosome band present on 19p
19p13.2-p12
Extensor Carpi Radialis Longus
Cervical Portion of Spinal Cord
SPINAL CORD, CERVICAL
The portion of the spinal cord located in the cervical region.
Cervical Spinal Cord
Cisterna Magna
Cerebellomedullary Cistern
Thymic Epithelial Cell Capable of Differentiating Towards Both Cortical and Medullary Cell Type
A reticular epithelial cell generated in the thymus that, in optimal conditions, can become either a cortex type of thymus cell that mediates positive selection or a medullary type of thymus cell that mediates negative selection of developing thymocytes.
Loose Connective Tissue
Irregular connective tissue, the intercellular matrix of which contains a sparse irregular network of collagen and elastic fiber bundles.
Areolar Tissue
A region of protein sequence similarity among members of the SRC family of cytoplasmic tyrosine kinases, and other proteins. The SH3 domain is a protein-binding domain that interacts with cytoskeletal proteins.
SRC Homology Region 3 Domain
SH3 Domain
Pubic Hair
Hair growing in the pubic area.
A sympathetic ganglion located at the sixth cervical vertebral level.
Middle Cervical Ganglion
Interstitial Segment of the Fallopian Tube
Physical location of GNB3_Gene
12: 6819636-6826818
Corneoscleral Coat
Cellular population adjacent to the renal corpuscle, composed of the macula densa, the juxtaglomerular cells, and the extraglomerular mesangial cells. It regulates the blood pressure by activating the renin-angiotensin-aldosterone system.
Juxtaglomerular Apparatus
Outer Granular Layer of the Cerebral Cortex
Small Pyramidal Cell Layer
The second layer of the cerebral cortex, composed of many small pyramidal cells and granule cells with short axons.
External Granular Layer of the Cerebral Cortex
Superficial Middle Cerebral Vein
A specialized, self-renewing cell in the bone marrow that has the capacity to differentiate into a cell with a particular function, but especially a myeloid progenitor cell.
Multipotent Bone Marrow Stem Cell with Wide Myeloid Potential
Lymphatic Vessel Smooth Muscle Tissue
17: 29714365-29711512
Physical location of CCL1_Gene
Cardiac Jelly
Metatarsal Bone Digit 5
11q23.2-q23.3
A chromosome band present on 11q
Chromosome 6 Physical Location
VALVE, CARDIAC
Cardiac Valves
Valve
Cardiac Valve
Any of the four heart valves, including the two atrioventricular valves and the two semilunar valves, that regulate the flow of blood through the chambers of the heart.
Central Tendon of the Diaphragm
Central Tendon of Diaphragm
RE System
A widely distributed collection of both free and fixed macrophages derived from bone marrow precursor cells by way of monocytes; their substantial phagocytic activity is mediated by immunoglobulin and the serum complement system. In both connective and lymphoid tissue, they may occur as free and fixed macrophages; in the sinusoids of the liver, as Kupffer cells; in the lung, as alveolar macrophages; and in the nervous system, as microglia.
Reticuloendothelial System
Cloacal Sphincter
Medial Collateral Ligament of the Knee
Physical location of APRIN_Gene
13: 32058624-32250157
Inferior Rectal Artery
10: 47127013-47233044
Physical location of ANXA8_Gene
Granulosa Cells
Granulosa Cell
Physical location of BRMS1_Gene
11: 65869132-65861387
17q23.1
A chromosome band present on 17q
A-Form DNA
A-DNA
A-DNA is a shorter and wider helix than B-DNA. Most RNA and RNA-DNA duplex are in this form. While deep, narrow major groove is not easily accessible to proteins but wide, shallow minor groove is accessible to proteins but with lower information content than major groove. A-DNA is the favored conformation at low water concentrations. Base pairs are tilted to helix axis and displaced from axis and sugar pucker is C3'-endo (in RNA 2'-OH inhibits C2'-endo conformation). When examined from the top of the helix, there is a large hole in the middle, the sugar phosphate backbone is at the edge of the helix, and the bases are displaced towards the edge.
Lateral Wall of Nasopharynx
Lateral Wall of the Nasopharynx
Fascia Lata
Interosseous Vein
Cricoarytenoid Joint
Decidua Parietalis
Lateral Posterior Nucleus of the Thalamus
Ventral Nerve Root
2: 201923719-201977938
Physical location of CASP8_Gene
5: 131907113-131905035
Physical location of IL5_Gene
Urinary Space
Bowman's Space
Superior Mesenteric Vein
A vein that follows the path of the superior mesenteric artery and joins with the splenic vein to form the hepatic portal vein.
Physical location of IL4R_Gene
16: 27248888-27283596
A chromosome band present on 6q
6q22-q23
Palate Bone
Subcostal Vein
Hilar Portion of the Hepatic Duct
The three small bones in the middle ear that transmit acoustic vibrations from the eardrum to the inner ear.
Auditory Ossicle
Bone of the Tympanum
Bone of Tympanum
Apocrine Cell
A glandular secreting cell in which the apical portion of the secreting cell is cast off along with the secretory products that have accumulated therein.
Apocrine
A chromosome band present on 20q
20q11.1
A chromosome band present on 17q
17q22-qter
Sequences on the 3' end of messenger RNAs that are not translated into protein. The 3'UTR is involved in many post-transcriptional regulatory pathways, including regulating translation efficiency, mRNA stability, and polyadenylation signals.
3' Untranslated Region
A chromosome band present on 8p
8p23.1
Clinical esophageal segment composed of smooth muscle. It corresponds to the inferior part of the lower third topographic segment of the esophagus.
ESOPHAGUS, ABDOMINAL
Abdominal Esophagus
A chromosome band present on 16q
16q22.2-q22.3
Other/Unique Body System
body system, other/unique
other/unique organ system
unique/other body system
organ system, other/unique
Embryonic Heart
Endocrine Ovary
A graft transferred from a donor of one species to a recipient of the same species but different genetic makeup.
Allograft
Axillary Vein
A chromosome band present on 11q
11q23.3
20q11.2
A chromosome band present on 20q
21q21.3
A chromosome band present on 21q
A small mass that is located in the inferior surface of the aortic arch. It functions as a peripheral chemoreceptor and is composed of glomus cells.
Aortic Body
Collateral Gyrus
Hind-Brain
2: 203067105-203257980
Physical location of BMPR2_Gene
A flat, scale-like epithelial cell found on the outer covering of the body.
Skin Squamous Cell
Perikaryon
Cell Body
Jugular Lymph Sac
Physical location of SMARCA4_Gene
19: 10932606-11033953
Minor Salivary Gland
A small salivary gland located in the oral cavity. It produces saliva.
Hematopoietic Tissue
Major Salivary Gland
A chromosome band present on 19q
19q13.31
A-V Bundle
Bundle of His
Atrioventricular Bundle
A bundle of specialized heart muscle fibers that conducts impulses from the atrioventricular node to the ventricles.
A gliding joint between the distal ends of the tibia and fibula and the proximal end of the talus.
Ankle
Ankle Joint
Sacral Vertebra
One of the usually five fused vertebrae forming the triangular bone just below the lumbar vertebrae.
Sacral Vertebrae
The structural elements that comprise a gene or transcription unit. Gene structures include the transcription initiation site, the protein coding sequences, intervening sequences, and the transcription termination or polyadenylation sites as well as the regulatory elements (enhancers, silencers, and the promoter) that lie outside the boundaries of the transcribed unit.
Gene Feature
Gene Structure/Organization
Seq Feature
Gene Structure
Gene Organization
Sequence Feature
Skeletal Muscle
MUSCLE, SKELETAL
Striated muscles that are under voluntary control of the organism. They are connected at either or both ends to a bone and are utilized for locomotion and other movements.
Skeletal Muscle Tissue
6p22.2-p21.3
A chromosome band present on 6p
A chromosome band present on 11q
11q23.1
Tract of Goll
The third lumbar vertebra counting from the top down.
L3 Vertebra
Inferior Palpebral Fold
Cortical Cell Layer
A fold of skin covering the tip of the penis.
Male Prepuce
Foreskin
Preputium Penis
Basilar Membrane
A sheet of amorphous extracellular material upon which the basal surfaces of epithelial cells rest. It is made up of two layers, the basal lamina and the reticular lamina. It is also associated with muscle cells, Schwann cells, fat cells, and capillaries; and is interposed between the cellular elements and the underlying connective tissue.
Posterior Column
5: 44424541-44340854
Physical location of FGF10_Gene
Epithelial Receptor Cell
A cell on the surface of the body or lining a body cavity that responds to physical and chemical stimuli by sending information to the central nervous system.
Physical location of LHX2_Gene
9: 123853443-123874996
A chromosome band present on 13p
13p12
A lymph node along the left gastric artery or greater omentum.
Gastric Lymph Node
LYMPH NODE, GASTRIC
Osteocyte
Mature osteoblasts that have become embedded in the bone matrix. They occupy a small cavity, called lacuna, in the matrix and are connected to adjacent osteocytes via protoplasmic projections called canaliculi. (MeSH)
Osteocytes
11p15.5
A chromosome band present on 11p
Terminal Ductal Lobular Unit
Terminal Ductal Lobular Units
TDLU
Joint Capsule
Dense fibrous connective tissue sealing the joint. It is attached to the bones and provides stability.
Articular Capsule
A chromosome band present on 11q
11q13.1-q13.2
The fifth thoracic vertebra counting from the top down.
T5 Vertebra
A chromosome band present on 19q.
19q13.33
Subsegmental Bronchus
A part the bronchial tree, an air passage arising from the segmental bronchus and passing to the naturally delimited part of lung segment (subsegment), where it further subdivides into smaller passages.
20p11
A chromosome band present on 20p
The extraembryonic membrane which contains the embryo and amniotic fluid. (MeSH)
Amnion
Amniotic
Physical location of GADD45A_Gene
1: 67862904-67866040
Pyramidalis
Musculus Pyramidalis
1q24-q25
A chromosome band present on 1q
Anterior Longitudinal Ligament
A ligament running the length of the anterior surface of the spinal column and thereby interconnects all the vertebral bodies.
Left Lobe of the Liver
A chromosome band present on 14q
14q31.1
A white blood cell that matures in the primary lymphoid organs and then circulates through the lymph system to the secondary lymphoid tissues where it interacts with antigens. A mature lymphocyte varies in size from 7 to 15 micrometer in diameter and is round or ovoid, but may be notched or slightly indented. The chromatin is generally diffusely dense and nucleoli are not usually visible.
Mature Lymphocyte
RGD Peptide
RGD Cell Adhesion Domain
RGD Motif
RGD Tripeptide Sequence
A consensus tripeptide that is recognized by and for binding to proteins of the integrin family, including many cell adhesion molecules. The one-letter codes for arginine - glycine - aspartic acid. This motif can be found in proteins of the extracellular matrix and it is recognized by different members of the integrin family. The structure of the tenth type III module of fibronectin has shown that the RGD motif lies on a flexible loop.
RGD Domain
Arginine-Glycine-Aspartic Acid Cell Adhesion Domain
RGD
Dilator Pupillae Muscle
16: 55996180-56007475
Physical location of CCL17_Gene
A chromosome band present on 19q
19q13.32
Foot Skin
Superior Hemorrhoidal Artery
Brown-colored adipose tissue that is present in higher concentrations in newborns and hibernating animals. It contains numerous small droplets of lipids and high numbers of mitochondria as its primary function is to generate body heat.
Brown Fat
BAT
ADIPOSE TISSUE, BROWN
Brown Adipose Tissue
A chromosome band present on 7p
7p22-p21
19: 1402288-1424237
Physical location of APCL_Gene
Basal Lamina Collagen
The part of a desmosome that is on the cytoplasmic side of this junction, consisting of desmoplakin, plakoglobins and plakophilins, which links the cytoplasmic intermediate filaments to the transmembrane cadherin receptor proteins.
Attachment Plaque
Lacrimal Nerve
DIX Domain
A domain involved in homo- and hetero-oligomerization.
11p15.3
A chromosome band present on 11p
Trachea Proper
Windpipe
Trachea
The fibrocartilaginous, mucous-lined tube passing from the larynx to the bronchi.
Lobus Quadratus
The main portion of the superior part of each hemisphere of the cerebellum, corresponding to the monticulus of the vermis; it is divided into two portions, the anterior and the posterior crescentic lobules, corresponding to the culmen and the declive of the vermis.
Lobulus Quadrangularis
Quadrate Lobe
Quadrangular Lobule of the Cerebellum
A chromosome band present on 6q
6q22.1-q22.3
21q21.2
A chromosome band present on 21q
Physical location of CUL5_Gene
11: 107384855-107482789
Iliac Lymph Sac
Thyrohyoid Ligament
Primordial Mediastinum
Frontal Gyrus
13q31.3
A chromosome band present on 13q.
Large Intestinal Muscularis Mucosa
The thin layer of smooth muscle fibers usually found as a part of the tunica mucosa deep to the lamina propria mucosae of the large intestine.
Intercostal Lymph Node
A lymph node located in the intercostal space of the thoracic wall.
LYMPH NODE, INTERCOSTAL
The narrow, central portion of the thyroid gland that crosses the trachea anteriorly and connects the two lobes of the gland.
Thyroid Gland Isthmus
1: 231817541-231656253
Physical location of BCAA_Gene
Physical location of BIK_Gene
22: 41831255-41850216
The nerve tissue composed of nerve cell bodies, unmyelinated nerve fibers and supportive tissue found in the brain and spinal cord. It is differentiated from the white matter by color of the tissues and the presence of more myelinated nerve cells in the white matter.
Gray Matter
20p13
A chromosome band present on 20p
21q21.1
A chromosome band present on 21.
Implantation Site
The anatomic site at which a tissue, graft, or radioactive material is inserted. This term may also refer to the site of the uterus at which the early embryo is attached.
SITE, IMPLANTATION
A chromosome band present on 11p
11p15.4
Membranous Canal of the Cochlea
Stratified squamous epithelium that covers the outer surface of the cornea. (MeSH)
Corneal Epithelium
The anatomic site at which damage or harm was suffered.
SITE, INJURY
Injury Site
Mesodermal Cell
An embryonic cell of the middle layer of three germ layers that gives rise to the musculoskeletal, vascular, urogenital systems, and connective tissue.
Mesoderm Cell
Spinal Cord Column
Infratentorial Brain
Infratentorial Nervous System
Infratentorial Anatomy
Erector Muscle of the Hair
Erector Muscle of Hair
Pilor Erectus
Tarsal Artery
A chromosome band present on 20p
20p12
Excitatory Synapse
A synapse in which the firing of the presynaptic cell increases the probability of firing of the postsynaptic cell.
Upstream Enhancer
An enhancer which is located 5' of the gene it regulates.
Gated Ion Channel
An ion channel in which the ion transport is regulated by a specific stimulus of either a change in membrane potential or binding of a ligand. Once the stimulus occurs the channel may undergo conformational changes that allow selective permeability.
Megakaryoblast
The precursor of a megakaryocyte.
Megacaryoblast
It refers to amino acid residue within a peptide that accepts fatty acid, palmitoyl group (C15H31-)as one of the reversible post-translational modifications. Protein palmitoylation is a thioester bond between palmitoyl-CoA and cysteine thiol. (NCI)
Palmitoylation Site
Palmitic Acylation Site
Thoracic Spinal Nerve Roots
Thoracic Spinal Nerve Root
1: 151190742-151253261
Physical location of IL6R_Gene
The external, visible part of the female genitalia surrounding the urethral and vaginal opening. The vulva includes the clitoris and inner as well as outer labia.
External Genitalia
Vulva
RGS Domain
RGS-Signaling Domain
Regulators of G Protein Signaling Domain
Typically 120 amino acids long, the RGS (Regulator of G protein Signaling) Domain is found in over 20 human proteins, bind activated G-alpha subunits, and are responsible for GAP function. Through other domains (e.g., DEP, PDZ, or PH) RGS proteins link to other signaling molecules. RGS domains contain conserved contiguous, or dispersed, GH subdomains (GH1, 2, and 3). All RGS domains share a tertiary structure of nine alpha helixes that form a right-handed anti-parallel bundle of helixes 4-7 and a terminal bundle of helixes 1-3 and 8-9. The 3-4, 5-6, and 7-8 helix loops form an interaction surface between RGS4 and Ga(i). RGS domains allosterically stabilize the G-alpha GTP binding pocket, accelerating GTPase activity. Thus, RGS Family members rapidly inactivate G protein signal transmission from seven transmembrane receptors in GPCR signaling pathways. (NCI)
The amphipathic helix motif is characterized by a repeating pattern of polar (P) and non-polar (N) side-chains that can be summarized as PxNPPNx. These clusters varied in length from 6 to 15 residues. The conserved non-polar positions are marked by a distinct absence of Asp, Asn and Ser, while other polar side chains are sometimes allowed.
Amphipathic Alpha Helix
Regions of chromosomal DNA attached to a structural component of the interphase nucleus termed the nuclear matrix, permitting the partitioning of DNA in the chromosomes into looped chromatin domains.
Matrix Attachment Region
MAR
3: 46224820-46218720
Physical location of CCR1_Gene
Golgi's Tendon Organ
Neurotendinous Spindle
Neurotendinous Organ
Golgi's Tendon Spindle
Golgi Tendon Organ
The Golgi Tendon Organ is located within the tendons found on each end of a muscle. It responds to increased muscle tension or contraction as exerted on the tendon, by inhibiting further muscle contraction, which protects against muscle damage. The proprioceptive sensory neuron of a Golgi tendon organ, projects to the motor neurons located within the ventral horn of the spinal cord, where the inhibition occurs. Unlike the muscle spindle, Golgi tendon organs do not indicate muscle length, but rather muscle tension.
Distal (long) arm of chromosome 5
5q
Chromosome 5 Long Arm
Chromosome 5 Distal Arm
Chromosome 5q
Left Renal Vein
A chromosome band present on 3q
3q25.1-q25.2
Physical location of HMGN3_Gene
6: 80001174-79967683
A chromosome band present on 17p
17p11.1
A fat storing cell.
Lipocyte
Type III Intermediate Filament
A type of intermediate filament that can form either homodimeric or heterodimeric complexes.
Type III IF
Vimentin-like Filament
Ascending Aorta Branch
An artery arising from the ascending aorta.
External Circumflex Artery
Extraembryonic Coelom
The specific restriction enzyme site within a vector into which an insert was placed.
Insertion Site
Insert Site
Cloning Site
Diaphysis of the Bone
A gland situated in the external auditory canal that produces a waxy secretion.
Ceruminous Gland
2cen-q13
A chromosome band present on 22q
Round Ligament
19: 11061132-11105490
Physical location of LDLR_Gene
Sciatic Artery
The faces of the lipid bilayer that are exposed to the cytoplasm and extracellular space. It is comprised of the hydrophilic heads of the lipid components, exposed surfaces and domains of transmembrane proteins, peripheral proteins and carbohydrate components.
Hydrophilic Portion of the Plasma Membrane
Thymic Lobule
A structure in a lobe of the thymus 0.5 -2 mm in diameter. The lobule is divided into an outer cortex and inner medulla. Lobules are separated from each other by connective tissue septa, however, the medullary tissue is continuous from lobule to lobule. Lymphocytes, reticular cells and macrophages are found in the lobules.
A chromosome band present on 17p
17p11.2
Physical location of FGFR3_Gene
4: 1762854-1777829
Inferior Constrictor Muscle of Pharynx
Inferior Constrictor Muscle of the Pharynx
Cricopharyngeus Muscle
Tissue located behind the iris and composed of muscle and epithelium. Its functions include the production of aqueous humor and changing the shape of the crystalline lens.
EYE, CILIARY BODY
Ciliary Body
Interphalangeal Joint of the Foot
Hyparterial Branch of the Right Main Bronchus
X: 151608808-151605221
Physical location of MAGEA3_Gene
Buccal
The surface of the tooth facing or in direct contact with the oral mucosa of the cheek.
Buccal Surface
Fontanelle
The four gaps in the skull of a neonate or fetus where the sutures converge. The bulging or depression of the membranous soft spots can be indicative of intracranial fluid buildup or systemic dehydration.
Cementum
Bone-like rigid connective tissue covering the root of a tooth from the cementoenamel junction to the apex and lining the apex of the root canal. It serves as an attachment for the periodontal ligament, thus assisting in tooth support.
The Voltage-Dependent Anion Channel (VDAC) is a small, abundant pore-forming eukaryotic protein in the outer mitochondrial membrane thought to form the major pathway for movement of adenine nucleotides through the outer membrane and to be the mitochondrial binding site for hexokinase and glycerol kinase.
Voltage-Dependent Anion Channel
Mitochondrial Porin
VDAC
Physical location of EEF2_Gene
19: 3936446-3927055
Portal Triad
An anatomical unit of hepatic tissue, composed of an interlobular vein of liver, an interlobular artery of liver and an interlobular bile duct. The triads are embedded in the interlobular connective tissue and travel together throughout the liver parenchyma.
10: 6144278-6093512
Physical location of IL2RA_Gene
Superficial Fascia
Pleuroperitoneal Membrane
Sputum
Material containing mucus, cellular debris, microorganisms and sometimes blood or pus. It is ejected through the mouth from the lungs, bronchi, and trachea.
8q22.3-q23.1
A chromosome band present on 8q
20: 57015697-57003635
Physical location of CTSZ_Gene
12q14.3-q15
A chromosome band present on 12q
Posterior Inferior Cerebellar Artery
PICA
Physical location of CST6_Gene
11: 65536038-65537552
Physical location of FADD_Gene
11: 69726917-69731144
A chromosome band present on Xp
Xp11.4-p11.21
Cochlear
Cochlear Organ
EAR, COCHLEA
Cochlea
The snail shell-shaped auditory component of the inner ear. It contains the sensory organ of hearing.
Gastric Muscularis Mucosa
Chromophobe Cell
A small, faintly staining cell with scanty cytoplasm and rounded or polygonal contours. It is found in clusters in the anterior lobe of the pituitary gland.
A thin layer of smooth muscle within the bladder lamina propria.
Bladder Muscularis Mucosa
Ligaments
Ligament
Band of fibrous tissue connecting bone to bone or cartilage to bone thereby supporting or strengthening a joint.
Subtalar Joint
Coronary Artery
ARTERY, CORONARY
A principal artery that originates in the aorta. It supplies blood to the muscular tissue of the heart.
BONE MARROW, VERTEBRUM
Bone Marrow, Vertebral
Bone marrow in a vertebral bone.
Groin
Inguinal
Inguinal Region
The lower region of the anterior abdominal wall located laterally to the pubic region.
Seminal Vesicle Secretion
The posterior cerebral artery is formed by the bifurcation of the basilar artery; it divides into three branches.
PCA
Posterior Cerebral Arteries
Posterior Cerebral Artery
Paraurethral Gland
8: 11763044-11739236
Physical location of CTSB_Gene
Physical location of ANGPT1_Gene
8: 108579430-108330886
A blood vessel located in the following sites: upper extremities, lower extremities, lower abdomen, head, or neck.
Peripheral Blood Vessel
Respiratory System, Lung
Lungs
One of a pair of viscera occupying the pulmonary cavities of the thorax, the organs of respiration in which aeration of the blood takes place. As a rule, the right lung is slightly larger than the left and is divided into three lobes (an upper, a middle, and a lower or basal), while the left has two lobes (an upper and a lower or basal). Each lung is irregularly conical in shape, presenting a blunt upper extremity (the apex), a concave base following the curve of the diaphragm, an outer convex surface (costal surface), an inner or mediastinal surface (mediastinal surface), a thin and sharp anterior border, and a thick and rounded posterior border.
Lung
Physical location of CSF2RB_Gene
22: 35642722-35659318
The immunoglobulin (Ig) constant chain domains and a single extracellular domain in each type of MHC chains are homologous and approximately 100 amino acids long, and include a conserved intra-domain disulfide bond. Members of the immunoglobulin superfamily are found in hundreds of proteins of different functions. The V-type immunoglobins contain the V regions of the Ig molecule. (From InterPro IPR003596)
Immunoglobulin-Like V-Type Domain
Zonula Adherens
The best understood cell-cell junction required for adhesion between cells in the epithelium. It seals adjacent epithelial cells together, preventing the passage of most dissolved molecules from one side of the epithelial sheet to the other. Adherens junctions are located most apically in insect cells and just basal to the tight junction in vertebrate cells. It is formed by the fusion of adjacent cell membranes which encircle the apical cell surface like a belt or fence based on homophilic association between molecules of the transmembrane protein E-cadherin, which is linked on its cytoplasmic side to the actin cytoskeleton via b-catenin (Drosophila Armadillo) and a-catenin. The adherens junctions and associated cytoskeleton form a continuous band (zonula adherens) around the apical circumference of each cell, thus uniting the cells of the epithelium into a coherent sheet.
Adherens Junction
Intermediate Junction
AJ
The rostral extensions of the ventricular system of the brain consisting of two cavities, one on each side of the brain within the central regions of each cerebral hemisphere. Cerebrospinal fluid flows from the lateral ventricles into the centrally third ventricle via the foramen of Monroe.
Lateral Ventricle of Brain
Ventricles, Lateral
Lateral Ventricles
Ventricle, Lateral
Lateral Ventricle
Right Hepatic Duct
Small Intestinal Lamina Propria
Dermomyotome
Physical location of DMBT1_Gene
10: 124310171-124393242
The smooth muscle tissue present in the tunica media which is the middle layer of the wall of an arteriole.
Arteriole Smooth Muscle Tissue
Collateral Fissure
Lumbar Nerve
Pinealocyte
A cell of the pineal body with long processes ending in bulbous expansions. Pineocytes receive a direct innervation from sympathetic neurons that form recognizable synapses. The club-shaped endings of pineocyte processes terminate in perivascular spaces surrounding capillaries.
Pineocyte
12: 10643431-10633039
Physical location of KLRA1_Gene
Physical location of GRB10_Gene
7: 50624473-50434254
19p13.3-2
A chromosome band present on 19p
19p13.3-p13.2
Cervical Spinal Nerve Roots
Cervical Spinal Nerve Root
16: 3870712-3716570
Physical location of CREBBP_Gene
Efferent Nerve
Neurons, Efferent
A neuron that sends impulses from the central nervous system to skeletal muscles, glands, and visceral organs.
Efferent Neuron
16: 28850779-28858164
Physical location of CD19_Gene
Proximal (short) arm of chromosome 5
Chromosome 5 Short Arm
Chromosome 5 Proximal Arm
5p
Tectorial Membrane
Molecular Layer of the Cerebral Cortex
The superficial layer of the cerebral cortex, containing nerve fibers, neuroglial cells, and occasional horizontal cells of Cajal.
Plexiform Layer of the Cerebral Cortex
The genetic material of the nucleus, consisting of deoxyribonucleoprotein, which occurs in two forms during the phase between mitotic divisions: 1) as heterochromatin, seen as condensed, readily stainable clumps; 2) as euchromatin, dispersed lightly staining or nonstaining material. During mitotic division the chromatin condenses into chromosomes.
Chromatin
GALT
Gut Associated Lymphoid Tissue
Non-encapsulated accumulations of lymphoid tissue in the alimentary tract that form a secretory immune system containing cells committed to IgA or IgE synthesis; It includes Peyer's patches and the lymphoid tissue which is present throughout the gastrointestinal mucosa.
Gut-Associated Lymphoid Tissue
RXY/FXpSXP Domain
The 14-3-3 family of proteins mediates signal transduction by binding to phosphoserine-containing proteins. RXY/FXpSXP Motif is one of two different binding motifs that are present in nearly all known 14-3-3 binding proteins. The14-3-3 dimer binds tightly to single molecules containing tandem repeats of phosphoserine motifs, implicating bidentate association as a signaling mechanism with molecules such as Raf, BAD, and Cbl. (from OMIM)
RXY/FXpSXP Motif
Cingulate Cortex
Physical location of CDKN1A_Gene
6: 36754465-36763087
Immunocompetent cells of the lymphoid and hemopoietic systems and skin. They function morphologically and phenotypically by presenting or processing antigens, thereby stimulating cellular immunity. They represent the most potent antigen-presenting cells and, therefore, play a critical role in the primary T cell immune response.
Dendritic Cells
Veiled Cells
Dendritic Cell
20pter-q12
A chromosome band present on 20p
Proximal Phalanx of the Hand
Proximal Phalanx of Finger
Proximal Phalanx of Hand
Fungiform Papilla
Ampullary Segment of the Fallopian Tube
The middle segment of the fallopian tube.
Carpal Joint
A joint formed between carpal bones.
JOINT, CARPAL
Fascia Adherens
Fascia adherens, similar to a zonula adherens, is a half Z line found in the cardiac muscle as one of the three intercalated disks. They anchor actin filaments from terminal sarcomeres and transmit contractile force between myocytes. (NCI)
An anatomical structure that consists of organs and organ subclasses responsible for certain body functions. Representative examples are the gastrointestinal system, urinary system, and hematopoietic system.
Body Systems
BODSYS
Organ System
The artery that delivers blood to the anterior portion of the spinal cord.
Anterior Spinal Artery
Extraperitoneal Area
BODY CAVITY, EXTRAPERITONEAL
Extraperitoneal Space
The space of the abdominal and pelvic cavities outside the peritoneum.
Physical location of BIRC1_Gene
5: 70352369-70300066
3: 133798792-133804080
Physical location of CCRL1_Gene
Physical location of LCP1_Gene
13: 45654395-45598060
Inferior Mesenteric Artery Branch
Physical location of EIF2B5_Gene
3: 185335826-185345798
Collagen Fiber
A branch of the common peroneal nerve. It innervates the surface of the calf and foot.
Superficial Peroneal Nerve
NERVE, PERONEAL, SUPERFICIAL
Mucosa of the Upper Lip
Mucosa of Upper Lip
The lining of the superior fleshy fold bordering the mouth. It is comprised of the epithelium, basement membrane, lamina propria mucosae, and lamina muscularis mucosae.
12: 52103908-52111579
Physical location of AMHR2_Gene
A membrane bound cytoplasmic compartment that drives molecular traffic between the plasma membrane and lysosome.
Endosome
Physical location of SIRPB1_Gene
20: 1548630-1491568
Pedal
Feet
The structure found below the ankle joint required for locomotion.
Foot
1: 164219484-164131543
Physical location of CD3Z_Gene
Larynx
Head and Neck, Larynx
voice box
The cartilaginous structure of the respiratory tract between the pharynx and the trachea. It contains elastic vocal cords required for sound production.
Physical location of CNK_Gene
1: 44935129-44940760
Basal Layer of the Endometrium
6p12.2
A chromosome band present on 6p.
Organ System, Gynecologic
Reproductive System, Female
Gynecologic Body System
Female Reproductive Tract
Organ System, Female Reproductive
Female Reproductive Organ System
Female Reproductive System
Female Reproductive Body System
Body System, Reproductive, Female
Gynecologic Organ System
Female Genital Tract
Body System, Gynecologic
Genital System, Female
Pseudostratified Columnar Epithelium
Purkinje Cell
The output neurons of the cerebellar cortex. (MeSH)
Cerebellar Purkinje Cell
Purkinje Cells
Purkinje's Corpuscles
Purkinje's Corpuscle
Purkinje's Cell
A chromosome band present on 6p
6p12.1
A chromosome band present on 11q
11q12.3
Physical location of HMGB2_Gene
4: 174630322-174627518
15q22.2
A chromosome band present on 15q
The tissue occupying the spaces of bone. It consists of blood vessel sinuses and a network of hematopoietic cells which give rise to the red cells, white cells, and megakaryocytes.
Reticuloendothelial System, Bone Marrow
Bone Marrow
Physical location of AMFR_Gene
16: 55016804-54952865
Conceptus
6q21-qter
A chromosome band present on 6q
Olfactory Lobe
Minus End of the Microtubule
The end of a microtubule where nucleation occurs.
Nongrowing End of the Microtubule
Minus End of Microtubule
Nongrowing End of Microtubule
Physical location of HLA-DPB1_Gene
6: 33151738-33162954
2: 108553285-108759407
Physical location of LIMS1_Gene
The portion of a proteolytic protein which causes hydrolysis and cleavage of other protein polypeptides.
Proteolytic Domain
Protease Domain
Terminal Ductal Lobular Unit Cell
An epithelial cell found in the small lobes at the end of the milk ducts inside the breast where the milk-producing cells are.
Vestibule
A chromosome band present on 17p
17p13.1-q25
A peripheral white blood cell that produces cytokines and kills infected target cells. It has a CD8 marker on its surface and has been activated by contact with MHC class I receptors and cytokines.
Mature Cytotoxic T-Lymphocyte
VEIN, RENAL
The veins which return blood from the kidneys to the vena cava.
Renal Vein
Thalamostriate Vein
Gastro-Colic Omentum
A large fold of peritoneum that hangs down from the stomach, and extends from the stomach to the posterior abdominal wall after associating with the transverse colon.
Greater Omentum
Embryo
Embryologic
Lateral Vestibular Nucleus
A site on a segment of a B-cell immunoglobulin heavy-chain gene where recombination (or rearrangement) can occur. It is involved in isotype or allotype switching and maturation of the immune response. Ig switch regions are found on genes encoding all five immunoglobulin heavy chains.
Immunoglobulin Switch Region
Blood Capillary
Radiocarpal Joint
Carpal
Wrist
Wrist Joint
A joint between the distal end of the radius and the proximal row of carpal bones.
Microtubule Triplet
A structure made of three cylindrical tubulin polymers.
A chromosome band present on 11q
11q12.1
Physical location of CALCA_Gene
11: 14950427-14946626
Tissue composed of a highly cellular outer cortex, and less cellular inner medulla. Both cortex and medulla contain epithelial cells, interdigitating dendritic cells, macrophages, and lymphocytes.
Thymic Tissue
THYMUS
Clitoris
The erectile tissue in the vulva. It is composed of the corpora cavernosa and the glans clitoris.
One of the two side by side replicas produced by chromosome replication in mitosis or meiosis. Subunit of a chromosome after replication and prior to anaphase of meiosis II or mitosis. At anaphase of meiosis II or mitosis when the centromeres divide and the sister chromatids separate each chromatid becomes a chromosome. (Biology-Text.com)
Chromatid
Atrioventricular Node
A-V Node
A small mass of specialized cardiac muscle fibers, located near the ostium of the coronary sinus and giving rise to the atrioventricular bundle of the conduction system of the heart.
MTS
Mitochondrial Targeting Signal
Mitochondrial Import Sequence
An amino acid sequence that directs the post-translational transport of a protein to the mitochondria. The sequence contains an alternating pattern of hydrophobic and positively charged amino acids.
Cochlear Labyrinth
Lateral Infratentorial Cistern
Special Sense Organ System
Left Ureter
Fimbria
The area of a tooth where the enamel and the underlying dentin are joined.
Dental-Enamel Junction
Perineum
The area located between the anus and vulva in females, and anus and scrotum in males.
Spleen Trabecular Artery
Splenic Trabecular Artery
A chromosome band present on 11q
11q12.2
Cervicomedullary Junction
Cervico-medullary Junction
SAM Motif
Sterile Alpha Motif
Sterile Alpha Domain
The approximately 70 amino acid SAM (Sterile Alpha Motif) domain has been identified in over 400 different proteins with diverse cellular function, from yeast to man. SAM domains have been implicated in mediating protein-protein interaction via the formation of homo and hetero-typic oligomers. The residues at the interface of the EphA4 and EphB2 SAM domain homodimers have been mapped, but the factors that determine specificity remain to be determined. (Pawson Lab, SLRI, Mount Sinai Hospital, 2003)
SAM Domain
The fourth portion of the large intestine (colon) that communicates with the transverse colon in the left-upper quadrant of the abdomen and the rectum below.
COLON, DESCENDING
Left Colon
Descending Colon
Left Thyroid Gland Lobe
The cone-like lobe of the thyroid gland that is located in the left side of the trachea.
THYROID GLAND, RIGHT LOBE
Distal Muscle
A muscle located away from the trunk of the body.
MUSCLE TISSUE, DISTAL
Extensor Carpi Ulnaris
7: 115906410-116032391
Physical location of C-MET_Gene
17: 59437839-59433688
Physical location of ICAM2_Gene
19: 46914377-46925686
Physical location of CEACAM5_Gene
The inner mitochondrial membrane encloses a fluid-filled matrix and is elaborately folded with shelf-like cristae projecting into the matrix. The components of electron transport chain are integral part of the inner membrane.
Inner Mitochondrial Membrane
Mitochondrial Inner Membrane
A specialized, self-renewing cell in the bone marrow that has the capacity to differentiate into a cell with a particular function.
Multipotent Bone Marrow Stem Cell
Physical location of EPHB1_Gene
3: 135996958-136461353
Periarteriolar Lymphoid Sheath
T-Cell Zone of Spleen
T-Cell Zone of the Spleen
Deep Cervical Lymph Node
Layer of the Rods and Cones
Layer of Rods and Cones
Nuclear Membrane
Nuclear Envelope
The double-layer membrane structure enclosing the nucleus in eukaryotic cells. It separates the DNA of the cell from the cytosol. For exchange of material, for example, proteins and mRNA, it is punctured with numerous nuclear pores.
A type of large, coiled, tubular, sometimes branched, specialized sweat gland that empties into the upper portion of a hair follicle instead of directly onto the skin surface. It has no secretory innervation but is sensitive to epinephrine in the bloodstream.
Apocrine Sweat Gland
Physical location of CLCA2_Gene
1: 86601846-86633961
Ascending Aorta
The portion of the aorta that emerges from the left ventricle and precedes the aortic arch.
Basal Lamina of the Vascular Endothelium
Physical location of IFNGR1_Gene
6: 137582200-137560315
Male Reproductive Tract
Penis and Other Genital
Body System, Reproductive, Male
Male Genital Tract
Genital System, Male
Male Reproductive Body System
Reproductive System, Male
Organ System, Male Reproductive
male genital
The sex organs of the male.
Male Reproductive Organ System
Male Reproductive System
A chromosome band present on 20q
20q13.2
Physical location of CCR9_Gene
3: 45903023-45919671
T-Immunoblast
A T-lymphocyte that has been transformed (activated) in response to antigenic stimulation. It will give rise to a population of T cells with specificity against the stimulating antigen.
3: 384700814-38499868
Physical location of ACVR2B_Gene
Superior External Articular Artery
Mature Tissue Histiocyte
A macrophage found in connective tissue. It is part of the reticuloendothelial system. The primary function of a mature tissue histiocyte is to phagocytose and digest tissue fragments especially apoptotic bodies and those fragments resulting from tissue injury and death.
Utero-Vesical Pouch
Posterior Longitudinal Ligament
Intercostal Artery
Left Spermatic Artery
Left Testicular Artery
Left Internal Spermatic Artery
SMALL INTESTINE, DUODENUM
A jointed tube 25-30 cm long that connects the stomach to the jejunum.
Duodenum
Quadriceps Muscle of the Thigh
A group of four powerful muscles in the front of the thigh. Their actions involve the extension of the knee joint.
Muscle, Quadriceps
MUSCLE, QUADRICEPS FEMORIS
Muscle, Thigh
A chromosome band present on 20q
20q13.1
A chromosome band present on 9q
9q22
Superior Temporal Convolution
Superior Temporal Gyrus
Under the microscope chromosomes appear as thin, thread-like structures. They all have a short arm and long arm separated by a primary constriction called the centromere. The short arm is designated as p and the long arm as q.
Chromosome Arm
Right Testis
A nucleus that is located in the olfactory tract.
Anterior Olfactory Nucleus
Endocardial Heart Tube
Conjunctival Epithelium
Sinovaginal Bulb
Haversian System
Osteon
Geniohyoid
A series of enzyme complexes in the inner mitochondrial membrane that transfer hydrogen ions into the intermembrane space. The activity of these enzymes creates an electrochemical gradient that is necessary for synthesis of adenosine triphosphate.
Electron-Transport Chain of the Respiratory Enzymes
C3H1 Zinc Finger
Zinc finger domains are thought to be involved in DNA-binding. Different types exist depending on the cysteine residue positions. C-X8-C-X5-C-X3-H type zinc finger proteins often function in cell cycle or growth regulation, e.g. human TIS11B (butyrate response factor 1) and mouse TTP nuclear protein. The splicing factor U2AF 35-kD subunit, which mediates protein-protein and protein-RNA interactions required for 3-prime splice site selection, also contains this domain. Different CCCH zinc finger proteins interact with the 3-prime UTR of various mRNA. This type of zinc finger is often present in two copies. (NCI)
Zinc Finger C-X8-C-X5-C-X3-H Type
Olfactory Cistern
Splenic Marginal Sinus
Spleen Marginal Sinus
Prostatic Glandular Cell
A secretory cell that produces and secretes prostatic fluid. Prostatic fluid contains citric acid, the enzyme fibrinolysin that liquefies the semen, acid phosphatase, a number of other enzymes and lipids. The secretion of the prostate is the first fraction of the ejaculate.
Head and Neck Part
Immunoglobulin-Like C2-Type Domain
Immunoglobulin C-2 Type Domain
The Ig constant chain domains and a single extracellular domain in each type of MHC chains are homologous and approximately 100 amino acids long, and include a conserved intra-domain disulfide bond. Members of the immunoglobulin superfamily are found in hundreds of proteins of different functions. This subfamily is the C-2-type and includes glycoproteins and other unrelated proteins with immunoglobulin domains eg. carcinoembryonic antigens and fibroblast growth factor receptors. (InterPro IPR003598)
Physical location of AKAP13_Gene
15: 83724875-840-93590
Vas Deferens Epithelium
The part of the brain located anterior to the parietal lobes at the front of each cerebral hemisphere.
Frontal Lobe
Frontal Cortex
1: 200897271-200891127
Physical location of KISS1_Gene
Physical location of IFNW1_Gene
9: 21132144-21130631
Convoluted Tubule
A chromosome band present on 8p
8p21-p12
Fetal Lung
A chromosome band present on 6p
6p24-p23
A U-shaped bone supporting the tongue. This bone is located at the base of the tongue and is suspended from the tips of the styloid processes of the temporal bones by the stylohyoid ligaments.
Hyoid Bone
Facial Artery
Urethralis
A stainable aggregation of protein, lipid or small molecules in the cytoplasm.
Cytoplasmic Inclusion
CORONARY ARTERY, RIGHT
A coronary artery that originates above the right coronary cusp and supplies blood predominantly to the right side of the heart.
Right Coronary Artery
1: 158332873-158324608
Physical location of FCGR3A_Gene
An embryonic cell that separates from the neural plate during formation of the neural tube and migrates to give several different lineages of adult cells: the spinal and autonomic ganglia, the glial cells of the peripheral nervous system, and nonneuronal cells, such as chromaffin cells, melanocytes and some haemopoietic cells.
Neural Crest Cell
Venous System Smooth Muscle Tissue
A chromosome band present on 2q
2q12-q14
Physical location of HMGA2_Gene
12: 64504458-64646266
Physical location of GDF8_Gene
2: 190752961-190745933
Xp11.3
A chromosome band present on Xp.
17: 59349930-59348295
Physical location of GH1_Gene
17q
Distal (long) arm of chromosome 17
Chromosome 17 Distal Arm
Chromosome 17 Long Arm
Physical location of DDX16_Gene
6: 30748736-30728886
The structure on the upper limb, between the elbow and the wrist.
Forearm
Skin of the Face
Salivary Gland Myoepithelial Cell
A chromosome band present on 4q
4q13-q21
A cell of the bone marrow that is derived from myeloblasts and will give rise to myelocytes, precursors of myeloid cells and neutrophil granulocytes.
Promyelocyte
Physical location of GPA33_Gene
1: 163791526-163753740
19p13
A chromosome band present on 19p
6: 336760-3356193
Physical location of IRF4_Gene
A chromosome band present on 5q
5q23-q31
Physical location of GPRC5C_Gene
17: 69939262-69955163
Cardia, NOS Gastric Cardia
STOMACH, CARDIA
Cardia
Cardia of the Stomach
Gastric Cardia
The area around the esophagogastric mucosal junction where the esophageal mucosa transitions into the gastric mucosa.
16: 30391572-30442007
Physical location of ITGAL_Gene
Anterior Carpal Artery
One of the arteries that deliver blood to the wrist. It arises from the radial artery and forms an anastomosis with the ulnar anterior carpal artery.
The smooth muscle tissue present in the tunica media which is the middle layer of the wall of an artery.
Artery Smooth Muscle Tissue
Prepontine Cistern
LYMPH NODE, INGUINAL
A superficial or deep lymph node located in the inguinal area.
Inguinal Lymph Node
Physical location of KOC1_Gene
7: 23283235-23123069
CA3 Field of the Cornu Ammonis
Genioglossus
An endocrine glandular cell located on the surface of the adrenal gland (adrenal cortex). It is responsible for the synthesis of glucocorticoids, aldosterone, and androgens.
Adrenal Cortical Cell
11q12-q13
A chromosome band present on 11q
A chromosome band present on 5q
5q23-q32
Internal Pterygoid Muscle
Immunoglobulin Variable Region
The portion of an antibody molecule that contains the three hypervariable regions in both the heavy and light chains. It is comprised of the amino terminal half of the light chains and at most a third of the heavy chains from the amino termini.
Sebaceous Gland of the Eyelash
Sebaceous Gland of Eyelash
Gland of Zeis
Stratum Intermedium
A star-shaped cell in the liver associated with the development of fibrosis. When stellate cells are activated in response to an injury, they proliferate and synthesize large amounts of extracellular matrix which results in deposition of scar or fibrous tissue.
Ito Cell
Hepatic Stellate Cell
The cells of the corpus luteum which are derived from the granulosa cells and the theca cells of the Graafian follicle. (MeSH)
Luteal Cell
Lutein Cells
Lutein Cell
Granulosa Lutein Cell
A cell of the corpus luteum of the ovary that is derived from the granulosa cells of the preovulatory follicle; it secretes progesterone and estrogen.
Lens Placodes
21: 39642835-39636112
Physical location of HMGN1_Gene
Male Breast
One of the two, usually rudimentary, mammary glands in the male.
A chromosome band present on 5q
5q23-q33
A chromosome band present on 20q
20q13.3
A chromosome band present on 8q
8q24.1
Ameloblast
Cylindrical epithelial cells in the innermost layer of the enamel organ. Their functions include contribution to the development of the dentinoenamel junction by the deposition of a layer of the matrix, thus producing the foundation for the prisms (the structural units of the dental enamel), and production of the matrix for the enamel prisms and interprismatic substance. (MeSH)
Ameloblasts
8q24.2
A chromosome band present on 8q
Cuneiform Cartilage
Isthmic Segment of the Fallopian Tube
Physical location of IL8RB_Gene
2: 218816252-218827481
The muscular structure at the distal portion of the stomach, opening into the duodenum.
Pyloric Sphincter
1: 151836835-151848325
Physical location of ADAM15_Gene
19: 627417-634389
Physical location of FSTL3_Gene
The central portion of the ovary, composed of loose connective tissue that contains blood vessels, lymph vessels and nerves.
Ovarian Medulla
Nissl Body
Mammary Gland Milk
MILK
Breast Milk
Milk produced by female mammals for the purpose of feeding their young.
Subcapsular Epithelium of the Lens
One of the 4 layers of the crystalline lens. It is found between the anterior surface of the capsule and the cortex. It is simple cuboidal epithelium responsible for creating new cells for the lens.
Anal Squamous Zone
The lower third segment of the anal canal. It is covered with stratified squamous epithelium.
Physical location of MAGED1_Gene
X: 51469782-51478486
8q24.3
A chromosome band present on 8q
Motor Nucleus of the Trigeminal Nerve
First Pharyngeal Pouch
Inferior Colliculus
Posterior Quadrigeminal Body
Transversalis
EYE, VITREOUS
Vitreous Body
A clear, avascular, gelatinous body that occupies the posterior chamber of the eye. It is bounded by the retina except anteriorly where it lies adjacent to the lens and iris.
A structurally or functionally defined protein region.
Protein Domain
Feature
Motif
Protein Feature
Domain
Region
Signature
Protein Motif
Protein Region
Chromosome Structure
Chromosomal Organization
Chromosome Organization
Chromosomal Structure
The 3-D organization of histones and other proteins on chromosomal DNA in the nucleus and allow for its form and function during cellular growth and division.
Serous gland with distended lumen. It includes the gland of Krause in the lacrimal sac and the gland of Wolfring on the inner surface of the upper eyelid.
GLAND, ACCESSORY OCULAR
Accessory Lacrimal Gland
Physical location of CXCL12_Gene
10: 44200551-44185613
Physical location of EPHA4_Gene
2: 222262515-222108254
Embryonic Respiratory System
Periodontium
Periodontal Ligament
Periodontal Membrane
The fibrous connective tissue surrounding the root of a tooth that separates it from and attaches it to the alveolar bone.
Physical location of GDF5_Gene
20: 33489441-33484563
1: 58961806-58958486
Physical location of JUN_Gene
A chromosome band present on 1p
1p35-p34.2
Left Common Carotid Artery
A chromosome band present on 10q
10q24.3-10qter
A domain that stabilizes alpha helices in proteins through a very efficient burial of hydrophobic side chains so that polar water molecules do not access them. As a result, the helices are quite stable. In fact, many structural proteins (keratins, tropomyosin, laminin) that have to bear considerable stress have a coiled-coil domain. Two basic essential features are common: (1) the overall secondary structure is alpha helical, (2) the hydrophobic residues are arranged on one side of the helices. The typical positioning of the hydrophobic residues in the coiled-coil domain can be often recognized from primary structure of the protein. The helices can be parallel or antiparallel. The former is common when the helices belong to different polypeptides and the latter prevails in coiled coils made up from a single polypeptide chain. The number of helices in the coil varies usually between 2 and 4.
Coiled Coil
Coiled Coil Domain
4-3 Hydrophobic Repeat
Coiled-Coil
Left-Handed Twist
Coiled-Coil Domain
Anterior Pole of the Lens
The central area in the anterior surface of the lens.
Carpal Bone
Carpus Bone
Hepatic Cord
Head of the Epididymis
Stratum Conjunctum
Naive Pregerminal Center B-Lymphocyte
A mature B lymphocyte that expresses IgM and IgD. It is found in peripheral blood, lymph nodes and secondary lymphoid organs, but has not moved into the germinal center of lymphoid organs. Once this cell encounters an antigen in the presence of helper T cells and becomes activated, it moves to the next stage of B-lymphocyte development.
The inner part of the lipid bilayer that is comprised of the hydrophobic tails of the lipid components and the membrane spanning domains of transmembrane proteins.
Hydrophobic Portion of the Plasma Membrane
Pre-B Lymphocyte
Lymphatic System
Lymphatic system (all sites)
Lymphatics
Reticuloendothelial System, Lymphatic System
The anatomic system that includes the lymph nodes, lymphoid tissues in various organs (spleen, thymus, tonsils, gastrointestinal tract), and lymphatic vessels. It is part of the immune system that offers protection against infections.
Node of Bizzozero
Mechanoreceptors in the organ of Corti. In mammals the outer hair cells are arranged in three rows which are further from the modiolus than the single row of inner hair cells. The motile properties of the outer hair cells may contribute actively to tuning the sensitivity and frequency selectivity of the cochlea. (MeSH)
Outer Hair Cell
Hair Cells, Outer
Type II Hair Cell
Physical location of CDC91L1_Gene
20: 3278550-32612008
Physical location of AKT1_Gene
14: 104330732-104306753
BTB/POZ Domain
The BTB/POZ domain is an approximately 120 amino acid long, hydrophobic region found in two distinct classes of transcriptional regulators that contain either a C-terminal basic leucine zipper motif (POK proteins) or a Zn-finger region (Bach proteins). This domain has been shown to form homo-dimers in a number of BTB/POZ domain containing proteins. (NCI)
BTB Domain
POZ Domain
Amniotic Fluid
Waters (Amniotic Fluid)
FLUID, AMNIOTIC
Aqua Amnii
Liquor Amnii
The fluid within the amniotic cavity which surrounds and protects the developing embryo. It is initially produced by the amnion and then later by the lungs and kidneys. The amount at term normally varies from 500 to 2000 ml.
Metacarpophalangeal Joint
The seventh rib counting from the top of the rib cage down.
Rib 7
Physical location of CYP2C9_Gene
10: 96688430-96739137
Outer Hair Sheath
Physical location of BCL6_Gene
3: 188946177-188921867
Erector Spinae
Flank
The region on either side of the body that extends from the last rib to the hip.
Hypochondrial Region
1p35-p32
A chromosome band present on 1p
A chromosome band present on 1p
1p35-p34.3
The eighth thoracic vertebra counting from the top down.
T8 Vertebra
The sixth rib counting from the top of the rib cage down.
Rib 6
Deep Palmar Fascia
Right Lung Alveolar Duct
Parachordal Cartilage
Renal Afferent Vessel
Two-layered muscularis mucosa extending into the small intestinal villi, where the smooth muscle cells form a longitudinal bundle in the centre of the villi. It is located between the lamina propria and submucosa of the small intestine.
Small Intestinal Muscularis Mucosa
Physical location of IL2RG_Gene
X: 70114424-70110580
Physical location of HSPB1_Gene
7: 75576574-75578263
12: 11958382-111998553
Physical location of DTX1_Gene
15: 64781738-64861380
Physical location of MADH6_Gene
The ninth rib counting from the top of the rib cage down.
Rib 9
Visceral Surface of the Liver
Enterochromaffin-Like Cell
Irregular-shaped argyrophilic cells which produce histamine, chromogranin A/pancreastatin, and an as yet unidentified peptide hormone. They are the predominant endocrine cell type of the oxyntic (acid-producing) mucosa of the stomach. ECL cells respond to gastrin by releasing their secretory products and this source of histamine acts as the positive paracrine stimulator of the release of hydrochloric acid from the parietal cell. (MeSH)
Enterochromaffin-like Cells
ECL Cell
ECL Cells
Median Cephalic Vein
UTR
A region of a messenger RNA that is not translated into protein.
Untranslated Region
Parahippocampal Gyrus
A primitive, undifferentiated blood cell which can undergo division and tends to give rise to a blood cell of the monocyte lineage.
Bone Marrow Stem Cell with Some Commitment to Monocytic Differentiation
1p36.3-p36.1
A chromosome band present on 1p
Nucleus of the Mesencephalic Tract of the Trigeminal Nerve
Higher Order Structure
Higher Order Chromatin Folding
Higher Order Chromatin Structure
Refers to various levels of DNA packaging in the chromosomes above that of the nucleosome. Includes the chromatin fiber and higher levels of folding such as loops.
The eighth rib counting from the top of the rib cage down.
Rib 8
One of the four quadriceps muscles, located in the middle of the front of the thigh. Its actions involve the extension of the knee joint and flexion of the hip.
Rectus Femoris
MUSCLE, RECTUS FEMORIS
11q22-q23
A chromosome band present on 11q
Homeodomain
The DNA-binding homeo domain was originally identified in transcription factor proteins encoded by homeobox genes (homeotic genes). The homeo domain is structurally similar to the helix-turn-helix DNA-binding domain of CRO and Lambda repressor.
Homeo Domain
A chromosome band present on 1p
1p36.3-p36.2
Substantia Gelatinosa of Rolando
Substantia Gelatinosa
Gelatinous-appearing material in the dorsal horn of the spinal cord, consisting chiefly of Golgi type II neurons and some larger nerve cells. (MeSH)
Pars Basalis
Posterior Inferior Frontal Convolution
Long Terminal Repeat
LTR
Identical DNA sequences found at either end of retrovirus proviral DNA, formed by reverse transcription of viral RNA.
The two innermost layers of tissue that cover the brain and spinal cord, the arachnoid mater and the pia mater.
Leptomeninges
leptomeningeal
NF-H
Neurofilament-H
Anterior Surface of Human Prostate
Anterior Surface of the Prostate
The aspect of the prostate facing the pubic symphysis.
Joint by Site
SH2 Domain
A region of protein sequence similarity among members of the SRC family of cytoplasmic tyrosine kinases, and other proteins. The SH2 domain usually mediates binding to phosphotyrosine and neighboring residues of target proteins.
The point on a chromosome where the normal DNA sequence is juxtaposed with DNA from another chromosome. Usually expressed as a band number designation (eg. t(9;22) (q34;q11) Philadelphia Chromosome)
Translocation Breakpoint
Physical location of NOS1_Gene
12: 116262302-116113699
Endothelium of the Glomerular Capillary
Tunica Adventitia
The outer connective tissue layer of the blood vessel wall. The adventitia consists of longitudinally arranged collagen fibers, elastic fibers, smooth muscle, fibroblasts, nerves and the vasa vasorum. It is thicker in veins than in arteries.
A carpal bone located between the lunate and pisiform bones.
Triangular Bone
PKC Binding Site
The second rib counting from the top of the rib cage down.
Rib 2
Physical location of EEF1A2_Gene
20: 61600949-61589810
13: 20533654-20446577
Physical location of LATS2_Gene
A chromosome band present on 8p
8p22-p21
The paired, mucosal lined air spaces located above the orbit and communicating with the nasal passages.
Sinus, Frontal
Frontal Sinus
Ovarian Follicle
Follicle
Physical location of MPP3_Gene
17: 39265136-39233695
Bone Marrow Blood-Forming Cell
Bone Marrow Cells
Bone Marrow Blood-Forming Cells
Cells contained in the bone marrow including fat cells, stromal cells, mega karyocytes, and the immediate precursors of most blood cells. (MeSH)
Short Bone
Osseous
Bones
Connective tissue that forms the skeletal components of the body.
Bone
Ciliary Muscle
Delta Cell
D Cell
Somatostatin Cells
Somatostatin Cell
D Cells
Somatostatin Secreting Cell
Cells found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. (MeSH)
Lateral Thyrohyoid Ligament
Urothelial Cell
A cell found in the layer of transitional epithelium in the wall of the bladder, ureter, and renal pelvis, external to the lamina propria.
A cleft or groove on the visceral surface of the liver located where the portal vein and hepatic artery enter and the hepatic ducts leave the liver.
Porta hepatis
Transverse Fissure
The third rib counting from the top of the rib cage down.
Rib 3
Cricothyroid Joint
Physical location of F8_Gene
X: 154175290-153627773
Vestibular Labyrinth
1: 150161148-150159257
Physical location of S100A12_Gene
Lymph Node Part
Ground Substance
The body substance in which tissue cells are embedded.
A grouping of hematopoietic cells derived from monocytes.
Histiocytic and Dendritic Cell
A chromosome band present on 7p
7p21
Venous Sinus
A large vein or channel for the circulation of venous blood, such as one of the sinuses of the dura mater.
Physical location of ALOX15_Gene
17: 4491709-4480965
Rib 4
The fourth rib counting from the top of the rib cage down.
True Vocal Cord
A lymphocyte found in the marginal zones of lymph nodes. It has a naive B lymphoid lineage and plays an important role in the early phases of immune response with its ability to rapidly differentiate into an antibody secreting cell. These cells can directly activate T cells, interact with other antigen presenting cells, transporting and concentrating antigen during the course of T-dependent and T-independent immune responses.
Marginal Zone B-Lymphocyte of Nodal Type
Physical location of EPOR_Gene
19: 11356019-11349475
Frontal Sulcus
Atlanto-Axial Joint
The joint located between the atlas and axis vertebrae.
19q13.1-q13.2
A chromosome band present on 19q
Ovarian Hilus
A chromosome band present on 7p
7p22
A protein domain that binds ATP and catalyzes its convertion to ADP and inorganic phosphate.
ATPase Domain
LIM Domain
Cysteine Rich Region
CRR Domain
The LIM domain is a zinc binding, cysteine rich motif consisting of two tandemly repeated zinc fingers. Unlike GATA type zinc fingers, LIM domains do not bind DNA but instead mediate protein-protein interactions. Functionally, LIM domain containing proteins have been implicated in cell lineage specification, cytoskeletal organization, and organ development.
Rib 5
The fifth rib counting from the top of the rib cage down.
Tonsillar Crypt
LUNG, LEFT
Left Lung
The 2-lobed lung located on the left side of the body.
Reading Frame
One of the three possible ways of reading a nucleotide sequence. As the genetic code is read in nonoverlapping triplets (codons) there are three possible ways of translating a sequence of nucleotides into a protein, each with a different starting point.
Frame
Physical location of GPR32_Gene
19: 55965670-55966740
Male Urethra
Frontopolar Artery
Type III Epithelial Receptor Cell
A light cell found in taste buds, characterized by afferent synaptic specializations to intragemminal nerve endings including increased density of the plasma membrane along the nerve and aggregations of synaptic vesicles, and by the presence of cored vesicles of 80-150 nm in diameter. The core is dense and the cell is immunoreactive for 5-hydroxytryptamine, neural cell adhesion molecule, and PGP 9.5.
Type III Cell
Four vertebral segments positioned at the base of the spine that are fused.
Coccygeal Vertebra
Fetal Kidney
Internal Cerebral Vein
Tunica Albuginea
1: 114836302-114822227
Physical location of BCAS2_Gene
Upper Lobe of the Kidney
KIDNEY, UPPER LOBE
Kidney Upper Lobe
Upper Lobe of Kidney
The lobe of the kidney located in the uppermost region of the kidney.
Chromosome
One of the bodies in the cell nucleus that is the bearer of genes, has the form of a delicate chromatin filament during interphase, contracts to form a compact cylinder segmented into two arms by the centromere during metaphase and anaphase stages of cell division, and is capable of reproducing its physical and chemical structure through successive cell divisions.
Chromosomal
One of the divisions of the lobar bronchus that supplies a bronchopulmonary segment.
Tertiary Bronchus
Segmental Bronchus
Sinus
A recess, cavity, or channel.
4: 78884157-78890165
Physical location of CXCL13_Gene
Any part of a transmembrane protein that projects into the environment surrounding a cell.
Extracellular Domain
External Domain
Zygomatic Arch
Zygomatic Bone
Zygoma
3q13.12
A chromosome band present on 3q
Ectodermal Cell
Ectoderm Cell
An embryonic cell of the outer layer of three germ layers. These cells give rise to the epidermis and neural tissue.
External Cuneiform Bone of the Foot
Lateral Surface of the Prostate
Lamina Lucida
Hepatic Flexure of the Colon
Hepatic Flexure of Colon
The bend of the colon at the juncture of its ascending and transverse portions.
Hepatic Flexure
A retinal layer composed of the basal lamina of Muller's cells.
Inner Limiting Membrane
Connecting Segment of the Photoreceptor Cell
15: 49403413-49288961
Physical location of CYP19A1_Gene
Arterial System Smooth Muscle Tissue
The smooth muscle tissue present in the tunica media which is the middle layer of the wall of the arterial system.
6: 33398676-33394367
Physical location of DAXX_Gene
Physical location of FLRT3_Gene
20: 14266270-14252643
A chromosome band present on 10q
10q26.13-q26.3
Epithelial Plica
Skin of Scalp and Neck
Skin of the Scalp and Neck
Sphincter Colli Superficialis
Xq27.1
A chromosome band present on Xq.
Physical location of GDF9_Gene
5: 132228124-132225180
Internal Plantar Artery
A chromosome band present on 10q
10q11-p12
Dorsum
The first rib counting from the top of the rib cage down.
Rib 1
Coracobrachialis
Coracobrachial Muscle
Coracobrachial
Mesoderm
Terminal Bronchiole Epithelium
Epithelium consisting of a single layer of cuboidal epithelial cells without goblet cells.
Chorionic Sac
The extraembryonic membranous sac surrounding the embryo of amniote vertebrates.
Mitochondrial Membrane
The double membrane structure surrounding the mitochondrion and separating it from the cell cytoplasm. The two membranes are separated by an intermembrane space. The electron transport chain resides in the inner mitochondrial membrane.
Masticatory Muscles
Masticatory Muscle
MUSCLE, MASSETER
Masseter Muscle
Muscles arising in the zygomatic arch that close the jaw. (MeSH)
A chromosome band present on 1q
1q23-q25
SNS
Sympathetic Nervous System
Centrosome
MTOC
Microtubule-organizing Center
A small region of cytoplasm adjacent to the nucleus that contains the centrioles and serves to organize the microtubules.
Palmar Fascia
Lip and Oral Cavity
A chromosome band present on Xp.
Xpter-p22.32
Prostate Fossa
Prostate Bed
The cavity just below the bladder where the prostate gland is located.
Medial Femoral Circumflex Artery
Medial Circumflex Artery
Lacrimal Bone
A small rectangular thin plate forming part of the medial orbit wall. It is located posterior to the frontal process of the maxilla and articulates with the inferior nasal concha, ethmoid, frontal, and maxillary bones.
Deep Circumflex Iliac Artery
Bartholin's Gland
Bartholin Gland
Sequences immediately following a point of interest.
3' Flank
Downstream Region
3' Region
19: 63758298-63754746
Physical location of BC-2_Gene
A chromosome band present on 8q
8q12-q13
Pancreatic Somatostatin Cell
Pancreatic Somatostatin Secreting Cell
Somatostatin Secreting Cell of the Pancreas
Somatostatin Cell of the Pancreas
A type of cell in the pancreatic islets that secretes somatostatin.
Delta Cell of the Pancreas
14: 64523260-64599123
Physical location of FNTB_Gene
15q23-15q24
A chromosome band present on 15q
Part of the chromosome bands present on the long (q) arm of chromosome 2.
2q31.1
Eustachian Valve
3: 52419049-52410067
Physical location of BAP1_Gene
10q21-q22
A chromosome band present on 10q
Frontal Artery
Descending Portion of the Duodenum
Descending Portion of Duodenum
Second Portion of Duodenum
Second Portion of the Duodenum
Longissimus Lumborum
3: 197124265-197078545
Physical location of ACK1_Gene
Parathyroid Gland Capsule
Physical location of LIG4_Gene
13: 107665883-107657795
Part of the chromosome bands present on the long (q) arm of chromosome 2.
2q31.2
Rib Shaft
Common Hepatic Duct
Chromosome 17p
Chromosome 17 Proximal Arm
Chromosome 17 Short Arm
17p
Proximal (short) arm of chromosome 17
Mylohyoid
Bone Cell
Osseous Cell
Any of the lymph nodes of the breast located under the ribcage, near the sternum.
LYMPH NODE, MAMMARY GLAND
Internal Mammary Lymph Node
Hand Digit 4 Phalanx
PHD Finger
Plant Homeodomain (PHD) Type Zinc Finger
PHD-Finger
C4HC3 Zinc Finger
PHD Finger Domain
PHD Finger Motif
A C4HC3 zinc-finger-like motif, the PHD finger is found in nuclear proteins thought involved in chromatin-mediated transcriptional regulation. Single or multiple fingers are found. A specific function is not yet known, but it could be involved in protein-protein interactions important for assembly/activity of multi-component transcriptional regulatory complexes. In CBP it is an integral part of the acetyltransferase enzymatic core domain and contributes to CBP transcriptional activity. PHD fingers fold into an interleaved Zn-finger chelating two Zn ions in an atypical cross-braced conformation also shared by the FYVE and RING fingers; the zinc sites are located at opposite ends of a beta-sheet. Surrounding loops vary significantly in length and sequence between these three domains. (NCI)
Flexor Digitorum Longus
Physical location of FZD3_Gene
8: 28407692-28477901
Coronary Ligament
Intrahepatic Portion of the Left Hepatic Duct
Surface of the Prostate
Surface of Human Prostate
Inferior Maxillary Bone
The lower jaw bone holding the lower teeth.
Mandibular
Bone, Mandibular
BONE, MANDIBLE
Mandible
Jaw
Lower Jaw
4: 6803638-6816969
Physical location of S100P_Gene
A chromosome band present on 10q
10q23-q24
Left Coronary Artery Branch
Superior Supratentorial Cistern
MYC Box
MYC boxes I and II, found in the N termini of all members of the MYC protein family, function to direct the degradation of the c-MYC protein. Both MYC boxes I and II contain sufficient information to independently direct the degradation of otherwise stably expressed proteins to which they are fused. At least part of the MYC box-directed degradation occurs via the proteasome.
Ectodermal
Ectoderm
The outer of the three germ layers of the embryo; it gives rise to epidermis and neural tissue.
Ganglion
A cluster of nervous tissue principally composed of neuronal cell bodies external to the central nervous system (CNS).
Neural Ganglion
Ganglionic
Ganglia
Peyer's Patch Germinal Center
Peyer Patch Germinal Center
Mantle Field
19p13.1
A chromosome band present on 19p
Xq24-q26
A chromosome band present on Xq
One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision. (MeSH)
Rod
Rods (Eye)
Rods
Rod Cell
Rods (Retina)
Rod Photoreceptors
Supraclavicular Lymph Node
Supraclavicular Lymph Nodes
A lymph node which is located above the clavicle.
Arc
The path or area of the body covered by a moving source of radiation during treatment.
Radiation Arc
Neurofilament-M
NF-M
Gallbladder Epithelium
H and N - Head And Neck
H and N
Head and Neck
For oncology, an area of the body generally construed to comprise the base of skull and facial bones, sinuses, orbits, salivary glands, oral cavity, oropharynx, larynx, thyroid, facial and neck musculature and lymph nodes draining these areas.
Anterior Portion of the Corpus Callosum Cistern
The frontal aspect of the cistern of the corpus callosum.
A chromosome band present on 19p
19p13.2
Perforating Artery
3: 106568880-106776709
Physical location of ALCAM_Gene
Fetal Liver
NF-L
Neurofilament-L
Subarachnoid Cistern
Physical location of COL4A6_Gene
X: 10748856-107204991
Germinal Layer
Precentral Gyrus
The point of junction of the sagittal and lambdoid sutures of the skull.
Lambda
Lambda Sutural Junction
The biting surfaces of the premolar and molar teeth.
Occlusal
Occlusal Surface
Sternohyoid
Apex of Lung
Lung Apex
The rounded, uppermost part of the lung, located above the level of the sternal end of the first rib.
Apex of the Lung
Thyroid Ima Artery
Thyroid Lowest Artery
Physical location of SMARCA3_Gene
3: 150287015-150230612
A chromosome band present on 8q
8q13-qter
Physical location of BRCA1_Gene
17: 38530934-38449844
Efferent Duct
Efferent Ductule
One of 12 to 14 small seminal ducts leading from the testis to the head of the epididymis.
Eyelash
Anyone of the short hairs that grow on the edge of the eyelid.
A chromosome band present on 19p
19p13.3
The irregular and largest tarsal bone that forms the heel.
Calcaneus
Calcaneum
Mature B-Lymphocyte at the Germinal Center Stage of Differentiation
A mature naive B-lymphocyte in the germinal center of secondary lymphoid organ that has had contact with an antigen and a helper T-cell.
T-Lymphocyte and NK-Cell
Group of lymphocytes. A T-lymphocyte is a white blood cell differentiated in the thymus that possesses highly specific cell-surface antigen receptors. A natural killer cell resembles a T-lymphocyte, but it does not express markers of either T or B cell lineage. Its cytotoxic activity is not antibody dependent.
T-Lymphocyte and Natural Killer Cell
11: 69299352-69296978
Physical location of FGF4_Gene
Physical location of DEFB1_Gene
8: 6722860-6715525
Pedicle of Vertebral Arch
A thick process on either side of the vertebral body that connects the latter to the vertebral arch.
Parietal Pleura
The outermost of the two pleural membranes. It consists of a thin basal layer of fibrous tissue upon which sits a continuous layer of mesothelial cells. The cells function to secrete the lubricant lining the pleural cavity.
Palatine Salivary Gland
A cell found in the pseudostratified epithelium lining the olfactory region of the nasal cavity. It gives rise to olfactory receptor cells and sustentacular cells.
Olfactory Basal Cells
Olfactory Basal Cell
Endocervical
Endocervix
The portion of the cervix which is lined by single columnar epithelium (mucosa).
11q13.3-q13.5
A chromosome band present on 11q
Opthalmic Artery
Physical location of FN1_Gene
2: 216126297-216050687
3: 42825980-42883779
Physical location of CCBP2_Gene
Skeletal System Part
Nucleus Caudatus
Caudate Nucleus
An elongated gray mass of the neostriatum located adjacent to the lateral ventricle of the brain. (MeSH)
Ventral Horn of the Spinal Cord
Palmar Hand Interosseus Muscle
Common Ulnar Vein
Fourth Ventricle of Brain
Fourth Ventricle of the Brain
Fourth Ventricle
The largest mass of lymphatic tissue in the body. It consists of cells and vessels contained within a capsule lined by mesothelium, from which trabecula enter the splenic parenchyma. The parenchyma is supported by a framework of reticular fibers. The spleen consists of two types of parenchymal tissue, the white and red pulp. The white pulp is composed of elongated cords of compact lymphatic tissue containing nodules. The red pulp is composed of pulp cords and splenic sinusoids.
SPLEEN
Splenic Tissue
Subendothelial Layer
Meninges
Any one of three membranes that surround the brain and spinal cord.
Physical location of DDX26_Gene
13: 50925135-50837364
Pineal Gland
pineal organ
Pineal Body
A small endocrine gland in the brain, situated beneath the back part of the corpus callosum, that secretes melatonin.
Trachea -The cartilaginous and membranous tube descending from the larynx and branching into the right and left main bronchi. Bronchi-The larger air passages of the lungs arising from the terminal bifurcation of the trachea.
Trachea and Bronchus
Respiratory System, Trachea, Bronchus
Trachea, Bronchus
A chromosome band present on 9q
9q21
Nuclear Outer Membrane
The nuclear envelope has two membranes, each with the typical unit membrane structure. They enclose a flattened sac and are connected at the nuclear pore sites. The outer nuclear membrane is continuous with the rough endoplasmic reticulum (ER) and has ribosomes attached. (NCI)
Outer Nuclear Membrane
2: 162834264-162824895
Physical location of GCG_Gene
Pluripotent Primordial Germ Cell
A chromosome band present on 3q
3q22.2
The tube carrying urine from the bladder to outside of the body.
Urethra
Endosteal Cell
A cell lining the medullary cavity of bone.
Xp22.32
A chromosome band present on Xp
A chromosome band present on 13q
13q14.2
Filamentous Actin
A fibrillar actin polymer.
F-actin
18q21.3
A chromosome band present on 18q
MENISCUS, MEDIAL
Medial Meniscus
A semicircular meniscus located towards the inner aspect of the knee joint.
Meniscus Medialis
Physical location of LIMD1_Gene
3: 45611355-45696569
Coronary Valve
1p13.1
A chromosome band present on 1p
1: 110018606-110004744
Physical location of EPS8L3_Gene
Upper Esophageal Sphincter
UES
A chromosome band present on 1q
1q25.2-q25.3
Gyri Breves Insulae
17q25
A chromosome band present on 17q
Physical location of CD14_Gene
5: 139992960-139991505
A chromosome band present on 2q
2q31-q33
A chromosome band present on 3q
3q22.1
Xp22.33
A chromosome band present on Xp
Elastic Fiber
Gastroesophageal Junction
The anatomical location where the esophagus joins to the stomach.
13q14.1
A chromosome band present on 13q
A chromosome band present on 22q
22q11.23
A chromosome band present on 1p
1p13.2
Pelvic Bone
BONE, PELVIS
Pelvis
The caudal portion of the trunk, bounded anteriorly and laterally by the two hip bones incorporating the socket portion of the hip joint for each leg. Posteriorly it is bounded by the sacrum and coccyx.
17q24
A chromosome band present on 17q
2q31-q32
A chromosome band present on 2 q
Vastus Lateralis
Polymorphonuclear Leukocytes
Polymorph
Neutrophil
Polymorphonuclear Cell
PMN
polymorphonuclear leukocyte
Blood PMN
Blood Neutrophil
Neutrophils
Granular leukocytes having a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.
Marrow Neutrophil
Neutrophilic Granulocyte
Heterophil Granulocyte
Polymorphonuclear Neutrophils
Blood Segmented Neutrophil
Neutrophilic Leukocyte
18q21.1
A chromosome band present on 18q
22q11.22
A chromosome band present on 22q
Physical location of FER_Gene
5: 108111422-108551272
A branch of the common peroneal nerve. It innervates the ankle and toes.
NERVE, PERONEAL, DEEP
Deep Peroneal Nerve
Membranous Urethra
Tibial Artery
Tibial Arteries
11: 102219550-102211743
Physical location of MMP3_Gene
A chromosome band present on 1p
1p13.3
The zone of the prostatic parenchyma that surrounds the proximal urethra.
Transitional Zone of the Prostatic Parenchyma
22q11.21
A chromosome band present on 22q
Distal Phalanx of Hand
Distal Phalanx of Finger
Distal Phalanx of the Hand
Interfollicular Area of the Lymph Node
Lymph Node Paracortex
Lymph Node Paracortical Region
Cleidooccipital
Physical location of FABP3_Gene
1: 31514981-31507594
Choroidal Artery
Trachea Submucosa
A neuroepithelial cell that is situated just beneath the ependyma, which is the lining membrane of the ventricles of the brain and of the central canal of the spinal cord.
Subependymal Cell
7: 13803555-13708330
Physical location of ETV1_Gene
Heterochromatin
A tightly packed area of chromatin that may function to protect chromosome integrity and regulate gene expression.
3p26-p25
A chromosome band present on 3p
13q14.3
A chromosome band present on 13q
9q34
A chromosome band present on 9q
A cell of the interstitial tissue of the renal parenchyma. A renal interstitial cell is one of two types. A type I interstitial cell is a fibroblastic cell that is active in the deposition and degradation of the interstitial matrix. It contributes to fibrosis in response to chronic irritation. A type II cell is a macrophage-derived mononuclear cell with phagocytic and immunologic properties. A type II cell is important in antigen presentation. Its cytokines contribute to recruitment of infiltrating cells, progression of injury, and sustenance of fibrogenesis.
Renal Interstitial Cell
1q41-q44
A chromosome band present on 1q
Head of the Humerus
The upper rounded part of the humerus that fits into the glenoid cavity of the scapula.
Retinal Ganglion
Ganglion Cells (Retina)
Retinal Ganglion Cells
Retinal Ganglion Cell
Cells of the innermost nuclear layer of the retina, the ganglion cell layer, which project axons through the optic nerve to the brain. (MeSH)
X: 47266274-47251174
Physical location of ELK1_Gene
Tendinocyte
An elongated cell with invisible cytoplasm and flattened, poorly-stained, nucleus. It is found in the tendon and is positioned in a very regular pattern of rows between parallel bundles of collagen fibers. It makes up the fibers and ground substance of the tendon.
3p26-p24
A chromosome band present on 3p
Gastrointestinal Tract, Stomach
Gastric
Stomach
An organ located under the diaphragm, between the liver and the spleen as well as between the esophagus and the small intestine. The stomach is the primary organ of food digestion.
Physical location of ERCC3_Gene
2: 127767982-127731096
Hypopharyngeal Aspect of the Aryteno-Epiglottic Fold
A basilar artery branch that supplies the anterior portion of the inferior surface of the cerebellum.
Anterior Inferior Cerebellar Artery
AICA
Physical location of CCNE1_Gene
19: 34994741-35007059
Soft Tissue
Physical location of FRAG1_Gene
11: 3786360-3804160
Iliopsoas Muscle
The portion of the upper extremity between the shoulder and the elbow. For clinical purposes this term is also used to refer to the whole superior limb.
Arm
A zinc finger protein domain that is comprised of a C2C2 sequence in close proximity to an incomplete PHD domain containing a C4C4 sequence.
ADD-Type Zinc-Finger
ATRX, DNMT3, DNMT3L-Type Zinc Finger
Artery
Arterial
A blood vessel that carries blood away from the heart.
4: 74666968-74686527
Physical location of AFP_Gene
Parietal Bone
One of two cranial bones that by their union form the sides and roof of the skull.
Germinal Center B-Lymphocyte
Physical location of CDK5_Gene
7: 150192644-150188547
A chromosome band present on 1q
1q41-q42
Cells of the gastric glands which secrete hydrochloric acid and intrinsic factor. (MeSH)
Parietal Cells
Oxyntic Cells
Parietal Cells, Gastric
Parietal Cell
Thyroid Gland Epithelial Tissue
The lining of the fleshy folds surrounding the mouth. It is comprised of the epithelium, basement membrane, lamina propria mucosae, and lamina muscularis mucosae.
Mucosa of Lip
Mucosa of Lip, NOS
Mucosa of the Lip
Middle Inferior Frontal Convolution
Pars Triangularis
Totipotent Primordial Germ Cell
One of the earliest cells of an organism that will be able to reproduce that kind of organism. It is able to develop into any variety of germ cell.
Hotspot
A genetic sequence at which mutations occur with an unusually high frequency.
Genetic Hotspot
Orbicularis Oculi
19p13.1-13.2
A chromosome band present on 19p
Epicardium
The outer membranous connective tissue layer of the heart tissue.
16: 87232502-87234383
Physical location of IL17C_Gene
Notochordal Plate
9: 132935667-132963441
Physical location of GTF3C5_Gene
Activated Skin-Homing T-Lymphocyte
A white blood cell, differentiated in the thymus, activated by an antigen that causes the cell to preferentially migrate to the skin.
Transformed Skin-Homing T-Lymphocyte
Axosomatic Synapse
A synapse between the axon of one neuron and the cell body of another neuron.
The superior portion of the heart located opposite to the apical portion. It is formed mainly by the left atrium.
HEART, BASE
Base of the Heart
12: 50631753-50677127
Physical location of ACVR1B_Gene
Mesenchyme
Embryonic tissue of mesodermal origin. Develops into connective tissue, blood vessels, and lymphatic tissue.
11: 49186798-49124764
Physical location of FOLH1_Gene
Mononuclear Blood Cell
A mixture of cells possessing a single nucleus, including monocytes and lymphocytes; blood leukocytes from which granulocytes have been separated and removed.
Mononucleated Blood Cell
Decidual
Decidua Graviditas
Decidua
The epithelial tissue of the endometrium.
B-Prolymphocyte
A developmental form in the B-lymphocyte series, intermediate between the B-lymphoblast and the mature B-cell.
Posterior Mediastinal Artery
Intercalated Duct of the Salivary Gland System
Septum Pellucidum
First identified in human hnRNPK protein, the conserved KH Domain of around 45-70 amino acids is present in a variety of nucleic acid-binding proteins. The domain may bind RNA in vivo. KH motifs are found in one or multiple copies, interspersed with RGG repeats, that may function cooperatively or, in single motif proteins, independently. KH domains can be separated into two groups: type-1 (beta-alpha-alpha-beta-beta-alpha) and type-2 (alpha-beta-beta-alpha-alpha-beta). The VIGXXGXXI sequence is preserved in the RNA binding motif between helix 1 and 2 (type-1) and helix 2 and 3 (type-2). The beta sheets are supported by alpha helixes. (NCI)
K Homology Domain
KH Domain
Nucleated Red Blood Cell
Red blood cells that are at the last stage of development, still containing a nucleus, that are found in the bone marrow and occasionally in the peripheral blood.
Cysteine-Rich Domain
The Cysteine-Rich Domain is usually found in two copies per protein. It contains up to four conserved cysteines. The family includes a subunit from heterodisulfide reductase and a subunit from glycolate oxidase and glycerol-3-phosphate dehydrogenase. (Pfam PF02754)
Striated Duct
The opening at the apex of the taste bud.
Taste Pore
Bone of the Extremity
Bone of Extremity
Outer Rod of the Corti
Outer Rod of Corti
A pelvic lymph node located along the obturator artery.
Obturator Lymph Node
A portion of the retinal rod cell largely consisting of a stack of discs (membrane infoldings that are incompletely separated in cones) that are continually replenished near the inner segment and that are shed from the distal end and phagocytosed by the pigmented epithelium.
Rod Outer Segment
Rod Outer Segments
ROS (rod outer segment)
Rod Outer Segment of the Retina
ILEUM, TERMINAL
The most distal section of the ileum that is continuous with the cecum.
Terminal Ileum
Obturator Internus Muscle
The part of the conjunctiva, a thin transparent mucous membrane, that covers the posterior surface of the eyelids.
Palpebral Conjunctiva
17: 76623557-76705827
Physical location of BAIAP2_Gene
Vagal Triangle
External Oblique Muscle
Descending Oblique Muscle
Physical location of AHR_Gene
7: 17111486-17158632
Mullerian Duct
Paramesonephric Duct
Blood reticulocyte
Diffusely basophilic erythrocyte
Reticulocytes
Marrow reticulocyte
Polychromatophilic Erythrocyte
Immature erythrocytes that have just undergone extrusion of their cell nucleus. They still contain some organelles that gradually decrease in number as the cells mature.
Reticulocyte
A small mass or body..
Corpuscle
Flexor Digitorum Profundus
Radial Artery of the Endometrium
Lobe of the Right Lung
Cochlear Nucleus
COCHLEAR NUCLEI
Located at the brainstem, this sensory organ receives auditory signals from the cochlear auditory nerve fibers. It is composed of the dorsal cochlear nucleus located on the dorsolateral surface of the inferior peduncle and the ventral (or accessory) cochlear nucleus located on the ventral aspect of the inferior peduncle.
Interosseous Artery
Thymus Medulla
Phagosome
A vesicle formed by the fusion of the plasma membrane around large particles during phagocytosis.
Tissue located below the ependyma lining the ventricles of the brain and central canal of the spinal cord. It is a dense feltwork of glial processes and is believed to contain neural stem cells.
Subependymal Tissue
Azygos Vein
Posterior External Jugular Vein
Enteroendocrine Cell
Kulchitsky Cell
A hormone-secreting cell present in the epithelium of the intestine.
The central and spongy portion of the bone.
Medullary Bone
Forebrain
The largest part of the brain composed of the cerebral hemispheres, thalamus, hypothalamus, and the limbic system.
Fore-Brain
Prosencephalon
BRAIN, FOREBRAIN
Frontal Nerve
15: 39593369-39583132
Physical location of LTK_Gene
Pancreatic Juices
pancreatic juice
Pancreatic Secretion
14q11.2
A chromosome band present on 14q
Physical location of CBFA2T1_Gene
8: 93176619-93040326
Physical location of ABL1_Gene
9: 130619261-130792614
The glandular epithelium that lines the endocervix.
Endocervical Glandular Epithelium
Phalanx
Phalanges
A bone in the fingers or toes.
16p12-p11.2
A chromosome band present on 16p
Skeletal muscle fibers having high myofibrillar ATPase activity, high glycolytic enzyme activities, and an intermediate glycogen content which produce a fast twitch. There are two types. Fast fatigable fibers, also called white fibers, have a low myoglobin content, and a small mitochondrial content, and fatigue rapidly due to their limited glycogen content and low capacity for oxidative metabolism. Fast fatigue-resistant fibers, also called red fibers, have a large mitochondrial content and a high myoglobin content, related to their resistance to fatigue. (MeSH)
Skeletal muscle fiber, type II
Muscle Fibers, Type II
Muscle Fibers, Fast-Twitch
Cervix Uteri
Genital System, Female, Cervix
Uterine Cervix
Uterus, cervix
CERVIX
The lower part of the uterus occupying the region between the isthmus of the uterus and the vagina. It is divided into supravaginal and vaginal portions.
A dilation of the duodenal papilla that is the opening of the juncture of the common bile duct and the main pancreatic duct. (MeSH)
Ampulla of Vater
Vater's Ampulla
Physical location of ITGB2_Gene
21: 45165232-45130314
Posterior Surface of the Kidney
Kidney Posterior Surface
Physical location of CASP10_Gene
2: 201873361-201919616
7: 79408791-79493376
Physical location of GNAI1_Gene
GLAND, BULBOURETHRAL
Bulbourethral Gland
Cowper's Gland
Gland, Cowper's
Paired exocrine glands located at the base of the penis, positioned posterior and lateral to the urethra, that produce and secrete a clear viscous liquid that lubricates the urethra in preparation for the passage of sperm.
Cowper Gland
15q22.1-q22.33
A chromosome band present on 15q
Eukaryotic Cells
Eukaryotic Cell
Cells of the higher organisms, containing a true nucleus bounded by a nuclear membrane. (MeSH)
2q12-q22
A chromosome band present on 2q
11: 104411067-104401445
Physical location of CASP1_Gene
Brachiocephalic Artery
Innominate Artery
Intermediate Fiber
Visceral Efferent Neuron
A cell that conducts a nerve impulse that originated in the central nervous system and proceeds towards one of the interior organs of the one of the three cavities of the body.
11: 34599244-34639357
Physical location of EHF_Gene
17: 31231490-31222611
Physical location of CCL5_Gene
Corneal Limbus
Corneoscleral Limbus
Chromosome 16 Physical Location
Brain Pia Mater
2: 128119977-128126443
Physical location of GPR17_Gene
An expansion of the subarachnoid space extending forward between the corpus callosum and the thalamus; it encloses the internal cerebral veins.
Ambient Cistern
Postcapillary Venule
Tract of Lissauer
Potassium Channel
Ion channel selective for potassium ions. There are several types, each with different functions.
Coccygeal Nerve
Left Lung Respiratory Bronchiole
It refers to amino acid tyrosine residue that was covalently modified by phosphate group (PO4-). (NCI)
Tyrosine Phosphorylation Site
Precursor NK-Cell
Precursor Natural Killer Cell
Intestinal enterocytes are low columnar to cuboidal cells comprising the majority of the epithelial tissue in the intestine and colon. They have both absorptive and secretory functions, absorbing water, sodium and short-chain fatty acids while secreting bicarbonate and potassium. Colonocytes originate from stem cells located at the base of the crypts. Enterocyte production, differentiation, and turnover occurs in topographically distinct regions of crypts. The transformation of colonic epithelial cells are frequently involved in colorectal cancers.
Large Intestinal Glandular Cell
Blast Cell
Blasts
Blast Cells
blast
Blast cells are in an immature (undifferentiated) stage in cellular development, occurring before the appearance of the definitive characteristics exhibited by fully differentiated cells.
The sixth thoracic vertebra counting from the top down.
T6 Vertebra
Thymic Epithelial Tissue
Physical location of BAIAP1_Gene
3: 65999265-65321090
Kinocilium
A motile cilium-like structure found in hair cells of the sensory epithelium of the inner ear. It has a core microtubule structure similar to that of a cilium.
Hair Follicle Inferior Segment
A specialized bulblike nerve ending located in the subcutaneous tissue of the skin; occurs abundantly in the skin of palms and soles and joints and genitals.
Pacinian Corpuscle
Vater's Corpuscle
Lamellated Corpuscle
Corpuscula Lamellosa
Vater-Pacini Corpuscle
9: 12769538-127656850
Physical location of ENG_Gene
Proximal Convoluted Tube
The posterior part of the cerebral hemisphere. (MeSH)
Occipital Cortex
Occipital Lobe
Physical location of LTBP2_Gene
14: 74148787-74034640
A chromosome band present on 20q
20q11.22
Cell of the Epidermis
An epithelial cell of the outer most layer of the skin.
Ear Skin
The thick fluid secreted by the mucus glands in the aerodigestive tract and the vagina.
Mucus
12: 61832857-61826483
Physical location of AVPR1A_Gene
Cervical Artery
Physical location of HMGN2_Gene
1: 26483139-26486599
Part of the chromosome bands present on the short (p) arm of chromosome 5.
5p14-p13
Other Specified Parts of Pancreas
Cranial Nerve
NERVE, CRANIAL
Any of the 12 paired nerves that originate in the brain stem.
Condensed Configuration of the Mitochondrion
Intercalated Duct of the Pancreas
An efferent neuron that sends impulses from the central nervous system to skeletal muscles.
Motor Neuron
Efferent Neuron
Motor Cell
Motoneuron
Motor Neurons
10p12
A chromosome band present on 10p
A bone on the lateral side of the tarsus between the calcaneus and the fourth and fifth metatarsal bones.
Cuboid Bone
1: 158288316-158302322
Physical location of FCGR2A_Gene
Pelvic Curve
Cornu Ammonis
CA
A chromosome band present on 3q
3q26.2-qter
Ciliated Respiratory Mucosa
LABIAL JUNCTION
Labial Commissure (Mouth)
Commissure of Lip
Commissure of the Lip
The junction of the upper and lower lips at the corner of the mouth.
1: 144237996-144322828
Physical location of BCL9_Gene
Esophageal Squamous Cell
A flat, scale-like epithelial cell that lines the upper and middle third of the esophageal lumen.
6p24.3
A chromosome band present on 6p
Sinoatrial Node
A cluster of specialized cells located in the upper area of the right atrium. These cells generate the electrical impulses that result in the normal sinus rhythm.
S-A Node
11q13.3-q14.1
A chromosome band present on 11q
B-DNA
Right-Handed DNA
B-Form DNA
A duplex of DNA is formed by two complementary chains that are arranged in an anti-parallel manner. B-DNA is about 20 Angstrom in diameter and a right-handed double helix with a wide major groove easily accessible to proteins and narrow minor groove. B-DNA is the most common DNA conformation in vivo and the favored conformation at high water concentrations. Base pairs are nearly perpendicular to the helix axis and sugar pucker is C2'-endo.
Long Bone
10q11.1
A chromosome band present on 10q
Immature B-Lymphocyte
A B-lymphocyte derived from a Pre B lymphocyte. It develops in bone marrow then exit via the central sinus. It goes through the vascular system to the spleen. It does not proliferate and differentiate in response to antigen, but instead responds to antigen by negative selection resulting in subsequent immune system tolerance to that antigen.
Trigonum Hypoglossi
Hypoglossal Triangle
Elastic Cartilage
2p13
A chromosome band present on 2p
Glans Penis
T-LGL
A thymus-dependent white blood cell that has been activated by contact with antigen and has enlarged by macromolecular synthesis with presence of large granules visible by light microscopy.
T-Cell Large Granular Lymphocyte
Portal Vein
A short thick trunk vein that transports blood containing the absorbed products of digestion from the intestine directly to the liver.
Hepatic Portal Vein
VEIN, PORTAL
Fetal Spleen
14: 92459245-92471389
Physical location of CHGA_Gene
Cytosol
The aqueous part of the cytoplasm within which various particles and organelles are suspended.
Cytosolic
Granules found in several types of cells, especially platelets, where they are the most numerous type of granule; contain secretory proteins.
Platelet Granule
Alpha Granule
Recto-Vaginal Pouch
Pouch of Douglass
Superior Vena Cava
Joint
The connection point between two bones or skeletal elements. The joint may be fixed or movable.
Articular
Joints
Articulation
Filopodia
A slender projection of the plasma membrane at the leading edge of migrating cells. This protrusion contains bundles of long, crosslinked actin filaments.
A chromosome band present on 10q
10q11.2
A chromosome band present on 12p
12p11.2
Squamocolumnar Junction
Ecto/Endocervical Junction
The border between the squamous epithelium that lines the ectocervix and the columnar epithelium that lines the endocervix.
Neuroblast
An embryonic nerve cell capable of differentiating into a neuron.
15q26.3
A chromosome band present on 15q
Physical location of DUSP3_Gene
17: 39211872-39199016
2p16
A chromosome band present on 2p
White Matter
The nerve tissue forming the bulk of the deep parts of the brain and the superficial parts of the spinal cord. It is composed of nerve cell processes, i.e. extensions (axons), which connect various grey matter areas of the brain to each other and carry nerve impulses to and from the nerve cell bodies within the central nervous system (neurons). Cerebral and spinal white matter does not contain dendrites. White matter is distinguished in that it is composed of axonal nerve fibers covered by a myelin sheath.
Triceps
Triceps Muscle
A skeletal muscle of the limb comprised of three muscular bundles called the heads that originate seperately and join together.
7p11
A chromosome band present on 7p
Node
Any bulge or swelling of an anatomical structure or part.
Hair Cell
Mechanoreceptors located in the organ of Corti that are sensitive to auditory stimuli and in the vestibular apparatus that are sensitive to movement of the head. In each case the accessory sensory structures are arranged so that appropriate stimuli cause movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system. (MeSH)
Ear Hair Cell
Hair Cells
Corti Cell
Superficial Femoral Artery
RNP Motif
RNA Binding Domains (RBD) mediate the interaction of RNAs with RNA-binding proteins. RBDs of about 90 amino acids consist of a four-stranded beta sheet adjacent to two alpha helixes. Within RBDs, conserved RNP-1 and RNP-2 motifs on the central beta sheets lie side by side; their side chains contact RNA.
RBD
RNA Recognition Motif
RNP-1 Signature
RNP Domain
Putative RNA-Binding Region
RNA Binding Domain
RRM
Adult Stem Cell
Mostly multipotent undifferentiated stem cells found in a specific tissue admixed with differentiated cells.
6p24.1
A chromosome band present on 6p
Pregnant Uterus
Physical location of FGF9_Gene
13: 21143875-21174187
Brain Arachnoid Membrane
12p11.1
A chromosome band present on 12p
2p15
A chromosome band present on 2p
5: 149473128-149413051
Physical location of CSF1R_Gene
10p13
A chromosome band present on 10p
Disintegrin Domain
It is an integrin binding domain originally identified in ADAM family proteins. (NCI)
Thyroid Artery
1q23-q31
A chromosome band present on 1q
A chromosome band present on 7p
7p12
Transitional Cells
Transitional Cell
Physical location of ALDH1A2_Gene
15: 56145198-56032919
Vocalis Muscle
Conical structures of the cortical portion of the kidney. The apices of these structures reach the periphery of the kidney, and the bases are applied to the medullary portion.
Pyramid of Ferrein
Lateral Ventricle Ependyma
Extensor Digitorum Lateralis
Cortical Bone
9p24.2
A chromosome band present on 9p
Hepatic Vein
Choroid Plexus Epithelium
Caveolae
Caveola
A small pocket, vesicle, cave, or recess communicating with the outside of a cell and extending inward, indenting the cytoplasm and the cell membrane. Such caveolae may be pinched off to form free vesicles within the cytoplasm. They are considered to be sites of uptake of materials into the cell, expulsion of materials from the cell, or sites of addition or removal of cell (unit) membrane to or from the cell surface.
One of two small cylindrical cell organelles composed of 9 triplet microtubules.
Centriole
URETHRA, PENILE
The portion of the urethra that spans the corpus spongiosum.
Penile Portion of the Urethra
2q22-q23
A chromosome band present on 2q
8q13
A chromosome band present on 8q
A chromosome band present on 15q
15q26.1
Tracheal Epithelium
Pseudostratified ciliated columnar epithelium with many Goblet cells, lining the lumen of the trachea. The basement membrane is thick.
The part of a tooth below the neck of the tooth which is covered by cementum.
Radix Dentis
Root of the Tooth
Tooth Root
Root of Tooth
Root
Tooth
Teeth
The hard bonelike structures in the jaws of vertebrates; primarily used for eating.
9p24.1
A chromosome band present on 9p
Physical location of CASP5_Gene
5: 104384909-104370180
An arterial branch arising from the anterior cerebral artery. It includes the callosomarginal artery, frontopolar artery, medial orbitofrontal artery, pericallosal artery, and recurrent artery of Heubner.
Anterior Cerebral Artery Branch
Intraembryonic Coelom
Facies Posterior Lentis
Right Atrium
11: 27699851-27633020
Physical location of BDNF_Gene
BA
Basilar Artery
Microchip Site
SITE, MICROCHIP
The anatomic site at which a microchip is implanted.
Inferior Oblique Muscle
A chromosome band present on 2q
2q22-q24
Nasal Nerve
12: 54869544-54843396
Physical location of SMARCC2_Gene
Supraorbital Vein
Supra-Orbital Vein
A chromosome band present on 22q
22q13.2-q13.31
Promontory
A chromosome band present on 3p
3p14.3-p14.2
A part the bronchial tree, arising from the primary bronchi, with each one serving as the airway to a specific lobe of the lung.
Secondary Bronchus
Lobar Bronchus
Systemic Vein
Eye Appendage
Lateral Mesoderm
Loose, filamentous areolar connective tissue between the muscularis mucosa and the muscular coat of the small intestine. It contains blood vessels, lymphatics, and nerves. The duodenal submucosa contains mucus-secreting Brunner's glands.
Small Intestinal Submucosa
One of the three lymph nodes of the pelvis: the superior gluteal, interior gluteal or sacral.
LYMPH NODE, ILIAC
Iliac Lymph Node
8q11
A chromosome band present on 8q
Blastomere
Embryonic Cells
Embryonic Cell
A cell formed in the first stages of embryonic development, after the splitting of the fertilized ovum, but before the formation of the blastula or blastocyst.
Osseous Labyrinth
Bony Labyrinth
2p12
A chromosome band present on 2p
A group of cells that remain of the Graafian follicle following ovulation. This structure is composed of endocrine tissue and produces progesterone. This is needed to prepare the uterine lining for implantation by the fertilized egg.
Corpus Luteum
Hydatid of Morgani
A chromosome band present on 16p
16p13.12
A rounded, club-shaped, nonciliated cell found in between ciliated cells in the epithelium of respiratory and terminal bronchioles. It has a secretory function.
Nonciliated Bronchiolar Epithelial Cell
Clara Cell
Venule Endothelium
Trophoblast
A chromosome band present on 6q
6q14.3
The area within the membrane of a lysosome.
Lumen of the Lysosome
A chromosome band present on 2p
2p11
Umbilical Fissure
Principal Sensory Nucleus of the Trigeminal Nerve
skeletal
Skeleton
Skeletal System
A chromosome band present on 16q
16q13-q21
LARGE INTESTINE, ANUS
Anal
The lower opening of the digestive tract, lying in the cleft between the buttocks, through which fecal matter is extruded.
Anus
Spinal Cord Pia Mater
20q13.2-q13.3
A chromosome band present on 20q
Splenic Sinus
Posterior Chamber of the Eye
EYE, POSTERIOR CHAMBER
Eye, Posterior Compartment
Posterior Chamber of Eye
Posterior Chamber (Eye)
A space within the eye located between the iris and the lens. It is filled with aqueous humor.
BONE, CONDYLE
A rounded bony projection at the end of the bone.
Condyle
17: 77474382-77469438
Physical location of MAFG_Gene
Interphase Cell
A cell in a resting state. Individual chromosomes are not visible. The cell performs all biochemical and physiologic functions and replication of chromatin occurs.
Resting Cell
Non-dividing Cell
resting
Distal (long) arm of chromosome 18
Chromosome 18q
Chromosome 18 Long Arm
Chromosome 18 Distal Arm
18q
Physical location of AKT3_Gene
1: 240332594-239977576
Perineal Muscle
A mature lymphocyte that has entered the peripheral blood system and has been activated into one of several mature B-cell subtypes.
Transformed Peripheral B-Lymphocyte
6q14.1
A chromosome band present on 6q
Deep Palmar Vein
Vesicle
A closed structure surrounded by a single membrane.
Cecum
A blind pouch-like commencement of the colon in the right lower quadrant of the abdomen at the end of the small intestine and the start of the large intestine.
LARGE INTESTINE, CECUM
Cecal
3: 61212164-59712987
Physical location of FHIT_Gene
12q24.2-q24.31
A chromosome band present on 12q
X: 139592243-139591945
Physical location of CDR1_Gene
Proximal (short) arm of chromosome 18
18p
Chromosome 18 Proximal Arm
Chromosome 18 Short Arm
A bony prominence situated on the upper surface of the body of the sphenoid bone housing the pituitary gland.
Sella Turcica
A chromosome band present on 1p
1p36.23-p35.1
Thoracic Sympathetic Nerve Trunk
Gastric Artery
Bronchus Smooth Muscle Tissue
Outer Wall of Vestibule
Tympanic Wall of the Vestibule
Tympanic Wall of Vestibule
Outer Wall of the Vestibule
Cell-to-Matrix Junction
Cell-to-Extracellular Matrix Junction
A cellular junction where cellular transmembrane integrin receptors bind to extracellular matrix proteins.
Focal Adhesion
Gallbladder Fundus
3p22.3
A chromosome band present on 3p.
Upper Lobe of the Lung
Upper Lobe, Lung
Lung Upper Lobe
The lobe of the right lung that lies above the oblique and horizontal fissures and includes the apical, posterior and anterior bronchopulmonary segments; in the left lung, the lobe lies above the oblique fissure and contains the apicoposterior, anterior, superior lingular and inferior lingular segments.
Couinaud Segment IVb
Couinaud segment IVb, corresponding to the medial segment of the left lobe of the liver, located inferiorly.
Left Inferomedial Segment
EXO II Motif
A conserved amino acid sequence (Asn-(X)3-Phe-Asp) in DNA polymerases that is required for 3' > 5' exonuclease activity.
EXO II Domain
A large irregular bone situated at the base and side of the skull, connected with the mandible via the temporomandibular joint. The temporal bone consists of the squamous, tympanic and petrous parts. The petrous portion of the temporal bone contains the vestibulocochlear organ of the inner ear.
Temporal Bone
PTB Domain
Phosphotyrosine Binding Domain
Phosphotyrosine binding (PTB) domains are 100-150 residue modules that commonly bind Asn-Pro-X-Tyr motifs. The PTB domains of the docking proteins Shc and IRS-1 require ligand phosphorylation on the tyrosine residue (NPXpY) for binding. More N-terminal sequences are also required for high affinity binding and conferring specificity. The peptide binds as a b-strand to an anti-parallel b-sheet, while the NPXpY motif makes a turn, positioning the pY for recognition by basic residues. The PTB domains of proteins such as X11, Dab, Fe65 and Numb apparently recognize NPXY or related peptide motifs, but are not dependent on ligand phosphorylation. In addition, the Numb PTB domain can bind an unrelated peptide that forms a helical turn.
3p22.2
A chromosome band present on 3p.
Physical location of ERBB3_Gene
12: 54760154-54782854
A chromosome band present on 15q
15q14
A chromosome band present on 7p
7p13
Iliocostalis Thoracis
Iliocostal Muscle
Thyroid Gland Oxyphil Cell
A large, granular eosinophilic cell derived from thyroid follicular epithelium by accumulation of mitochondria
Thyroid Gland Oxyphilic Cell
Hurthle Cell
Hurthle Cells
Cavernous Sinus
5: 169657400-169607667
Physical location of LCP2_Gene
Integument
An organ that constitutes the external surface of the body. It consists of the epidermis, dermis, and skin appendages.
Skin
Epigastric Vein
Superficial Temporal Vein
Common Carotid Artery
Immature Centriole
Procentriole
An immature form of a centriole or basal body.
9q32
A chromosome band present on 9q
A chromosome band present on 3p
3p26.2
Bone Marrow, Tibia
Bone marrow in the tibia bone.
Ventricular Fold
False Vocal Cord
A chromosome band present on 13q
13q14-q21
Mitotic Chromosome
Condensed chromosomes observed during the M phase of the cell cycle. Individual chromosomes can be discerned and differentiated morphologically.
17q21
A chromosome band present on 17q
Xq12
A chromosome band present on Xq.
2q33.1
A chromosome band present on 2q
Lingula of the Lung
A small tongue-like projection from the lower portion of the upper lobe of the left lung.
Proline-Rich Region
Proline-Rich Domains may be involved in heterotypic protein-protein interactions in signal transduction or other pathways. Found in signaling and structural proteins, WW domains are composed of approximately 40 amino acids folded as a stable, triple stranded beta-sheet that recognize proline-rich sequences. Some WW domains show a remarkable similarity to SH3 domains, which also appear to recognize some proline-rich sequences. Ena/VASP (Drosophila Enabled/Vasodilator-Stimulated Phosphoprotein) Family members regulate actin filament assembly, often through association with binding partners that display a proline-rich FPPPP motif. Ena/VASP proteins interact with these partners via the highly conserved Ena/VASP homology 1 (EVH1) domain. (NCI)
Proline-Rich Domain
A chromosome band present on 15q
15q15
Vasa Vasorum
Synovial Cell
A fibroblast that lies between the cartilaginous fibers in the synovial membrane of joints.
Synovial Cells
A spheroid joint located between the heads of the metatarsal bone and the base of the proximal phalanx of the toe.
Metatarsophalangeal Joint
9p12-p11
A chromosome band present on 9p
17: 68088158-38105358
Physical location of CNTNAP1_Gene
Nephrogenic Ridge
Nephrogenic Cord
One of four small oval masses that protrude slightly from the underside of the thalamus and function as synaptic centers on the way to the cerebral cortex.
Geniculate Body
The basic unit of contractility in a muscle fiber.
Sarcomere
9q33
A chromosome band present on 9q
Cephalic Vein
One of five superficial veins of the upper extremity, beginning at the radial aspect of the wrist area, wrapping around the forearm and emptying into the axillary vein.
Vena Cephalica
VEIN, CEPHALIC
A cone-shaped projection in the shaft of the femur in which the iliopsoas muscle is attached.
Lesser Trochanter
Lesser Trochanter of the Femur
1q25-q31.1
A chromosome band present on 1q
A cell found in the nervous system. It includes glial cells, neuroblasts, and olfactory cells.
Neuroepithelial Cell
A tube-like structure composed of the vas deferens and surrounding tissue layers, that runs from the abdomen to each of the testicles.
testicular cord
Spermatic Cord
Thyrohyoid
A chromosome band present on 6q
6q22.33
A chromosome band present on 7p
7p15
Anal Mucosa
The mucous membrane lining the anus.
Fibrin
Dental Sac
7p21.2
A chromosome band present on 7p
A chromosome band present on 11q
11q14.2-q14.3
16: 30815429-30822382
Physical location of CTF1_Gene
shinbone
BONE, TIBIA
Tibia
A bone located between the femur and the tarsus, being part of the lower leg.
Androgen Response Element
Androgen response element is the target binding element for activated androgen receptor homodimer. The consensus sequence for this high-affinity androgen receptor-binding is the palindromic sequence GGT/AACAnnnTGTTCT, though could deviate considerably in natural promoter sequences. The most well-characterized in this regard is the promoter of the PSA (prostate-specific antigen) gene.
ARE
Hippocampal Sulcus
Mucus-Secreting Cell
It is the epithelium cell that produces mucin gel adherent to the mucosal surface. Mucus-secreting cells are widely distributed through the body. (NCI)
Urachal Epithelium
Opening of the Pulmonary Vein
Thoracic Spinal Cord
SPINAL CORD, THORACIC
Thoracic Portion of Spinal Cord
The portion of the spinal cord located in the thoracic region.
Sacral Bone
One of the five bones of the spine that fuse to create the sacrum.
A chromosome band present on 7p
7p21.3
Supraspinatus
Xp11.4-11.21
A chromosome band present on Xp.
17q23
A chromosome band present on 17q
9q31
A chromosome band present on 9q
Pharyngeal Membrane
Physical location of EPHA2_Gene
1: 16228780-16196139
Lacrimal Sac
Endothelium
Endothelial
The layer of cells that lines the cavities of the heart and of the blood vessels (Endothelium, Vascular) and lymph vessels (Endothelium, Lymphatic), and the serous cavities of the body, originating from the mesoderm.
Posterior Cricoarytenoid Ligament
Cricoesophageal Tendon
Cytotrophoblastic Cell
A polygonal, mononucleate cell resembling the cells of the inner layer of the trophoblast, having prominent nucleoli and clear, eosinophilic or basophilic cytoplasm.
T-Lymphocyte, Cytotoxic
cytotoxic T lymphocyte
Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC), in vivo during a graft-versus-host (GVH) reaction, or after immunization with an allograft, tumor cell or virally transformed or chemically modified target cell. These cells are distinct from natural killer cells and from killer cells mediating antibody-dependent cell cytotoxicity.
Cytotoxic T-Lymphocyte
Cytolytic T-Cell
Cytotoxic T Cells
killer T cell
T-Lymphocytes, Cytotoxic
Cytotoxic T-Lymphocytes
CTL
Cytotoxic T Cell
Cell-Mediated Lympholytic Cells
The part of the spleen that consists of nodules and other lymphatic concentrations.
White Pulp
Splenic White Pulp
Physical location of DPYD_Gene
1: 98098600-97255323
Chromosome 13 Physical Location
Helix
A protein secondary structure motif. Amino acids are arranged in a right-handed rod like structure stabilized by hydrogen bonds between the C=O and the N-H groups of the main chain. Types include:alpha-helix, 3.10 helix and pi-helix.
Protein Helix
Nervous System, Ear
A chromosome band present on 5q
5q21
Dartoic Muscle
14q23
A chromosome band present on 14q
Spinal Nerve
NERVE, SPINAL
Spinal Roots
Spinal Nerves
Paired nerves that arise from the spinal cord. In all, there are 31 pairs of spinal nerves located in the human body.
Posterior Wall of the Nasopharynx
Posterior Wall of Nasopharynx
17: 77868741-77866035
Physical location of CD7_Gene
Second Pharyngeal Pouch
Mononuclear phagocytes derived from bone marrow precursors but resident in the peritoneum. (MeSH)
Macrophages, Peritoneal
Peritoneal Macrophage
Superior Maxillary Bone
Growing Follicle
Retroperitoneal Lymph Sac
Central Lobe
An invaginated portion of the cerebral cortex forming the base of the sylvian fissure. It is part of the lateral side of the cortex and its function includes the processing of emotions, memory, and higher autonomic control.
Insular Cortex
Island of Reil
Insula
Lobus Insularis
Insular Region of the Brain
Oral Mucosa
Moist tissue lining the oral cavity, containing mucous secreting glands.
MUCOSA, ORAL
Skin of the Extremity
A chromosome band present on 14q
14q22
The specialized cytoplasm in an oocyte.
Ooplasm
22: 35870462-35846382
Physical location of IL2RB_Gene
Cervix Epithelium
A chromosome band present on 6q
6q22.33-q24.1
A chromosome band present on 9q
9q22.32
Physical location of CASP3_Gene
4: 185945750-185924000
A cerebral fissure that originates near the occipital lobe and terminates below the corpus callosum.
Calcarine Sulcus
Canalis Radicis Dentis
The portion of the dental pulp cavity in the root of a tooth, extending from the pulp chamber to the apical foramen. More than one canal may be present in a single root.
Haptens
A substance that can act as an epitope for an antibody but that lacks immunogenicity unless coupled to a larger carrier molecule.
Hapten
Lens Fiber
Fetal Heart
Superior Intercostal Vein
A chromosome band present on 2q
2q32.2-q32.3
Hepatogastric Ligament
A cell usually of the epidermis that resembles a basal cell.
Basaloid Cell
Lymph Node Cortex
The portion of the lymph node that contains nodules with germinal centers where B lymphocyte mature into plasma cells after activation. The nodules are separated by diffuse lymphatic tissue, lymph sinuses and trabeculae.
Palatoglossus Muscle
Palatoglossus
The bodily system of organs and tissues, primarily the bone marrow, spleen, tonsils, and lymph nodes, involved in the production of blood.
Hematopoietic System
Hematologic Organ System
Organ System, Hematologic
Hematologic Body System
Hematopoietic Body System
Body System, Hematologic
15p
Proximal (short) arm of chromosome 15
Chromosome 15 Short Arm
Chromosome 15 Proximal Arm
Periderm
A chromosome band present on 5q
5q12.2-q13.3
Physical location of LGI1_Gene
10: 95507668-95547906
3q26.3
A chromosome band present on 3q
Sebaceous Gland Duct
Brachial Artery
An artery originating at the axillary artery and branching into the radial and ulnar arteries.
ARTERY, BRACHIAL
Epithelial Stem Cell
ESOPHAGUS, CERVICAL
Clinical esophageal segment composed of skeletal muscle. It corresponds to the superior part of the upper third topographic segment of the esophagus.
Cervical Esophagus
Chromosome 15 Distal Arm
Chromosome 15 Long Arm
15q
Distal (long) arm of chromosome 15
Axillary Lymph Node
One of approximately 20-30 lymph nodes in chain formation that traverse the concavity of the underarm to the clavicle.
ALN
LYMPH NODE, AXILLARY
Axillary Node
Axillary Lymph Nodes
13q14.12-q14.2
A chromosome band present on 13q
Saccule
Vagus Nerve
Pneumogastric Nerve
Cranial Nerve X
Tenth Cranial Nerve
NERVE, VAGUS
Metanephrogenic Blastema
Metanephric Mass of the Intermediate Mesoderm
Purkinje's Cell Layer of the Cerebellum
Purkinje Cell Layer of the Cerebellum
Physical location of ATF2_Gene
2: 175858404-175763515
Right Renal Artery
11: 65424573-65416268
Physical location of FOSL1_Gene
Myenteric Nerve Plexus
Longus Colli
Common Bony Limb
Internal Wall of the Tympanum
F Box Domain
F Box
The F-box consists of three helices. The H1 helix packs orthogonally with the H2-H3 antiparallel pair. The F-box domain is a 42-48 amino acid conserved domain found at the N-terminus of F-box proteins. F-box proteins act as adaptor components of the modular E3 ubiquitin ligase SCF complex that functions in phosphorylation mediated ubiquitination. The F-box domain mediates interaction with Skp1, which links F-box proteins to a core ubiquitin-ligase complex composed of Rbx1, cdc53/Cul1 and the E2 conjugating enzyme cdc34. The C-terminal region of F-box proteins are also composed of various modular domain that interact with target substrates, often in a phosphorylation dependant manner.
Nasal Bone
One of two small oblong bones placed side by side at the middle and upper part of the face.
11: 86344081-86334370
Physical location of FZD4_Gene
Distal Common Bile Duct
Right Lumbar Region
Rib Tubercle
9q22.31
A chromosome band present on 9q
Dorsalis Pedis Artery
An artery of the dorsal surface of the foot, originating from the anterior tibial artery of the lower leg. The following arterial branches originate from the dorsalis pedis artery: the arcuate artery of the foot and deep plantar artery.
Inferior Pancreatico-Duodenal Artery
Physical location of CUL3_Gene
2: 225275619-225160374
Granular Layer of the Cerebellum
Physical location of F7_Gene
13: 112808106-112822346
Gallbladder Smooth Muscle Tissue
Abutment
The tooth, teeth, or implant that supports a fixed bridge or removable prosthesis.
Thermoreceptors
Thermoreceptor
A chromosome band present on 3q.
3q26.1
Thoracic Duct
22: 28274230-28228872
Physical location of C22orf19_Gene
Autolysosome
Autophagolysosome
An organelle formed by the fusion of an autophagosome with the lysosome, where the contents of the autophagosome are degraded.
Physical location of GTF3C4_Gene
9: 132575282-132594368
LYMPH NODE, THORACIC
Thoracic Lymph Node
Lymph node located in the thoracic cavity.
Molecular Layer of the Cerebellum
11: 35117306-35208150
Physical location of CD44_Gene
Contractile system directs cell movement and is responsible for maintaining or changing cell shape. The system consists of many specialized cytoplasmic proteins, including actin, myosin, tubulin, kinesin, other cytoskeletal and contractile system proteins. (NCI)
Contractile System
5: 178354730-178337938
Physical location of GRM6_Gene
Bone Marrow Stem Cell at the Earliest Stage of Myeloid Differentiation
An undifferentiated cell which can undergo division and can give rise to any of the early stage myeloid cells.
Peripheral Nervous System
That part of the nervous system consisting of the nerves and neurons that reside or extend outside the central nervous system.
Posterior Infratentorial Cistern
Classic Lobule
Muscle and Fasciae of the Thorax
Tonsillar Tissue
Nodules of lymphoid tissue located on either side of the back of the nasal canal and throat.
TONSIL
Posterior Surface of the Prostate
Posterior Surface of Human Prostate
Large Granular Lymphocyte
LGL
Large Granular Lymphocytes
Membrane-Attached Polyribosome
Membrane-Attached Polysome
A cluster of ribosomes that is associated with the rough endoplasmic reticulum.
The skin or integument covering the arm.
Arm Skin
The convex bulge in the gum below a tooth caused by the underlying structure of the tooth root.
Root Eminence
14: 90790022-90769965
Physical location of GPR68_Gene
Vein of Galen
Great Cerebral Vein of Galen
17q12
A chromosome band present on 17q
A chromosome band present on 14q
14q24
The sac that envelops the embryo. It is composed of extraembryonic membranes.
Gestational Sac
14q11-q12
A chromosome band present on 14q
19: 54149929-54156867
Physical location of BAX_Gene
SITE, TATTOO
Tattoo Site
The anatomic site at which a tattoo is present.
The lateral and inferior border of the stomach. Attached to it is the greater omentum.
Greater Curvature of the Stomach
Greater Curvature
Greater Curvature of Stomach, NOS
A chromosome band present on 15q
15q15.1-q21.1
Physical location of LYL1_Gene
19: 13074681-13070848
Gastric Rugae
Intrahepatic Large Bile Duct
An intrahepatic bile duct that is grossly visible and has a wall that is composed of fibrous tissue.
Left Suprarenal Vein
17: 39340415-39308258
Physical location of MPP2_Gene
Cochlear Nerve
Cochlear Root of Acoustic Nerve
Cochlear Root of Eighth Cranial Nerve
Cutaneous Trunci
Right Inferior Frontal Convolution
5: 134102105-134115746
Physical location of CAMLG_Gene
Tendons
A band of fibrous connective tissue that joins bone to muscle.
Tendon
4q26-q27
A chromosome band present on 4q
A chromosome band present on 6q
6q25.3
Internal Iliac Artery
Middle Phalanx of the Hand
Middle Phalanx of Finger
Middle Phalanx of Hand
Right Innominate Vein
Ascending Parietal Convolution
A convolution in the temporal lobe between the interparietal sulcus and the central sulcus.
Physical location of IGFBP2_Gene
2: 217323633-217354662
Perineural Tissue
Tissue that surrounds nerves.
The part of the mediastinum that is located between the upper part of the sternum in the front and the upper thoracic vertebrae in the back.
Superior Mediastinum
MEDIASTINUM, SUPERIOR
Breast Part
Breast-Related Entity
A cell that serves to provide support and protection and perhaps contribute to the nutrition of principal or other cells of the nervous system.
Supporting Cell of the Nervous System
Tooth 19
First Molar
Six-year Molar
Tooth #19
The first, permanent, six-year molar of the lower left arch as defined by the Universal tooth numbering system.
Neck Skin
Part of the chromosome bands present on the long (q) arm of chromosome 15.
15q22.33
Outer Mitochondrial Membrane
Mitochondrial Outer Membrane
The mitochondrial outer membrane contains the multi-subunit machinery responsible for the specific recognition and translocation of precursor proteins.
Septum Primum
12p13.2-p12.3
A chromosome band present on 12p
Meridian
Physical location of HTR2A_Gene
13: 46368176-46305514
A chromosome band present on 7q
7q21.3-q22.1
Hindgut
Anterior Circumflex Artery
An axillary artery branch with distribution to the humeral head and biceps muscle.
1: 19383946-19375770
Physical location of AKR7A2_Gene
The endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.
Sarcoplasmic Reticulum
A chromosome band present on 6q
6q25.1
Fleshy fold which surrounds the opening of the mouth.
Lip
Sinus Venosus
Terminally differentiated cells comprising the majority of the external surface of the intestinal epithelium. Unlike goblet cells, they do not produce or secrete mucins, nor do they secrete cryptdins as do the paneth cells. (MeSH)
Enterocytes
Enterocyte
Any of the skeletal muscles that form the buttocks. These muscles are responsible for hip abduction and extension as well as movement of the thigh.
Gluteal Muscle
MUSCLE, GLUTEUS
Physical location of CDK10_Gene
16: 88280579-88290263
16: 70665292-70668646
Physical location of HPR_Gene
Right Renal Vein
Hepatic Artery
Physical location of COX6C_Gene
8: 100975071-100959548
Epencephalon
16q2
A chromosome band present on 16q
Somatopleure
Superior Cerebellopontine Cistern
A chromosome band present on 2p
2p13-q13
HMG-Box
The HMG-Box Domain binds to and bends the minor groove of the DNA. This domain can recognize and bind to altered DNA conformations, such as stem-loops, four-way junctions, and specifically kinked or underwound DNA. (Mol Cell Biol 1999 Aug;19(8):5237-46)
HMG-1 Domain
The soft tissues in close proximity to the testis.
Paratesticular Soft Tissue
Physical location of FOXO3A_Gene
6: 109897719-109108661
Dermatome Region
Vitreous Fluid
The clear colorless transparent jelly that fills the posterior chamber of the eyeball.
Vitreous Humor
X: 151573740-151569863
Physical location of MAGEA12_Gene
Tooth 16
The upper left 3rd molar, as defined by the Universal tooth numbering system.
Crosslinker
Cytoskeletal Crosslinker
A protein that links cytoskeletal filaments to one another and modulates both the formation and stability of cellular structures.
Physical location of ESR1_Gene
6: 152220800-152516520
Central Sulcus of Rolando
Fourth Ventricle Ependyma
Eyebrow
BASS
Basolateral Sorting Signal
The polymeric immunoglobulin receptor is a model system to study protein traffic in epithelial cells. This receptor travels first to the basolateral surface where it can bind polymeric IgA or IgM. The receptor is then endocytosed and delivered to endosomes. The receptor is sorted into transcytotic vesicles which are exocytosed at the apical surface. The 103 amino acid cytoplasmic domain of the receptor contains several sorting signals. The 17 residues closest to the membrane are an autonomous signal for basolateral sorting. For endocytosis there are two signals, both of which contain tyrosines. Finally, transcytosis is signaled by serine phosphorylation. (From PubMed PMID1813030 and NCI)
The bodily fluid that fills the membranous labyrinth of the inner ear.
Endolymph
Rete Ovarii
Posterior Parietal Artery
The upper left 2nd molar, as defined by the Universal tooth numbering system.
Tooth 15
A cell from the outside layer of tissue on the blastocyte, a hollow ball of cells formed in the early development of an embryo. It attaches the blastocyte to the endometrium of the uterus and supplies nourishment to the embryo. The chorion and amnion are derived from these cells.
Trophoblastic Cell
Thrombocytes
Thrombocyte/Platelet
An irregular, disc-shaped element in the blood that assists in blood clotting. Platelets are not blood cells, they are fragments of large bone marrow cells called megakaryocytes.
Hayem's elementary corpuscle
Bizzozero's corpuscle/cell
Marrow platelet
Platelet
Reticuloendothelial System, Platelets
Blood Platelets
Thrombocyte
Deetjeen's body
Blood Platelet
Platelets
PLT - Platelet
Right Brain Hemisphere
Right Cerebral Hemisphere
Left Hepatic Duct
11q14
A chromosome band present on 11q
Foramen Apicis Dentis
A minute opening at or near the apex of a root of a tooth, but on occasion located on the side of a root, which allows passage to the vascular, lymphatic and neural structures supplying the pulp. Sometimes the main opening branches near the apex to form two or more apical openings.
Oculomotor Nucleus
Reproductive System Part
Circular Sulcus
Columnar Cell
Columnar Cells
An epithelial cell that is taller than it is wide. The nucleus is oval, usually situated at the base of the cell. These cells line large glands and ducts.
12: 25295121-25249447
Physical location of KRAS2_Gene
Left Atrium
Left Atrium of Heart
NERVE, MEDIAN
Median Nerve
A branch of the brachial plexus that extends along the anterior aspect of the forearm and the hand.
A chromosome band present on 11q
11q13
Sequence
The sequence of nucleotide residues along an RNA chain.
RNA Sequence
The lower left 2nd molar, as defined by the Universal tooth numbering system.
Tooth 18
A direct linkage between an artery and a vein.
AV Anastomosis
AV Shunt
Arteriovenous Anastomosis
Arteriovenous Shunt
Intracranial Venous System
Buttock
Either of the fleshy mounds in the rear pelvic area of the human body formed by the gluteal muscles.
Choroidal Fissure
Physical location of HMGB3_Gene
X: 149822337-149827902
Superior Vestibular Nucleus
Styloglossus
The upper, smaller part of the prostate between the ejaculatory ducts and the urethra.
Median Lobe of Human Prostate
PROSTATE GLAND, MIDDLE LOBE
Middle Lobe of the Prostate
Hilar Area of the Right Lung
Tunica Intima
The inner most layer of the blood vessel wall. The consistency of the intima will vary depending on the type of blood vessel, but will always have an endothelial layer with a basal lamina. It may contain collagen and elastic fibers.
Physical location of CCL27_Gene
9: 34652689-34651894
Tooth 17
The lower left 3rd molar, as defined by the Universal tooth numbering system.
Subglottis
The area of the larynx below the vocal cords down to the trachea.
Marginal Zone
A chromosome band present on 11q
11q12
A dinucleotide repeat on chromosome 2 that serves as a marker for microsatellite instability in colorectal cancers.
D2S123 Dinucleotide Repeat
D2S123
A columnar epithelial cell found in the bronchi. It secretes mucus.
Mucinous Goblet Cell
Mucinous Bronchial Cell
17: 22898282-22968585
Physical location of KSR_Gene
Physical location of NOVA1_Gene
14: 26136535-25984929
The roof of the oral cavity. It separates the oral cavity from the nasal cavity.
Palate
S1 Vertebra
Physical location of FGF2_Gene
4: 124105468-124176995
An epithelial cell that produces sebum, a thick, semi-fluid substance composed of fat and epithelial debris from the cells of innermost layer of the epithelium.
Sebocyte
The site of the surgical exposure of an internal organ or tissue.
Exteriorization Site
SITE, EXTERIORIZATION
Gland of Wolfring
The portion of the light and heavy chains of immunoglobulin molecules where the variable and constant regions meet.
Immunoglobulin Joining Region
Physical location of FRS3_Gene
6: 41588608-41845892
16: 54070604-54097652
Physical location of MMP2_Gene
Poly-A Addition Site
The site within the 3' untranslated region of a gene where polyadenylation of the transcribed RNA takes place. Usually consists of the sequence AATAAA.
Intrinsic Tongue Muscle Vertical Component
Opening of Vena Cava
Foramen Quadratum
Opening of the Vena Cava
The anterior surface of the lens of the eye.
Anterior Surface of the Lens
A triangular shaped structure, i.e., one of the triangular segments of heart valve or a raised area of the biting surface of a tooth.
Cusp
13: 24941115-25492996
Physical location of ATP8A2_Gene
19p13.12
A chromosome band present on 19p
Intralaminar Nucleus
Physical location of EPS8L2_Gene
11: 696120-717727
Distal Convoluted Tubule
Popliteal Vein
10p11.23
A chromosome band present on 10p
Notochord
The rod-shaped body, composed of cells derived from the mesoblast and defining the primitive axis of the embryo. In higher vertebrates it is replaced by the vertebral column. (MeSH)
Parathyroid Gland Parenchymal Cell
Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate through direct electrical connections which are sometimes called electrical synapses.
Synapse
19p13.11
A chromosome band present on 19p
Bronchiole Epithelium
19: 10242779-10258291
Physical location of ICAM1_Gene
PENIS
The erectile tissues of the penis. It includes the dorsal corpora cavernosa and the ventral corpus spongiosum. Their structure consists of multiple vascular spaces that are surrounded by smooth muscle.
Penis Erectile Tissue
A chromosome band present on 10p
10p11.21
A lymph node located in the retropharyngeal space behind the upper part of the pharynx.
LYMPH NODE, RETROPHARYNGEAL
Retropharyngeal Lymph Node
Perineal Artery
Costovertebral Joint
Posterior Surface of the Liver
Mature B-Cell
A descendant of a lymphoid stem cell that differentiates into either a plasma cell or a memory B cell in response to a specific antigen. The mature B lymphocyte develops and differentiates in the bone marrow.
Mature B-Lymphocyte
Balbiani Body
A collection of mitochondria, germinal plasm and fragments of both the endoplasmic reticulum and Golgi that is found next to the nucleus during early stages of oocyte development.
Uterovaginal Primordium
Vaginal Cuff
The part of the apical portion of the vagina which is closed with sutures following total hysterectomy.
Primordial Interventricular Septum
11p15.2-p15.1
A chromosome band present on 11p
Any DNA sequence involved in the regulation of genetic processes such as transcription and replication.
Regulatory Element
Regulatory Region
Ventral Mesogastrium
Psoas Major
Musculus Psoas Major
Psoas Magnus
Chromosome 5 Physical Location
7q21-q22
A chromosome band present on 7q
A chromosome band present on 12q
12q14-q15
Physical location of DCC_Gene
18: 48121156-49311286
Protoplasmic Astrocyte
10: 98054202-98088311
Physical location of DNTT_Gene
Floor of the Fourth Ventricle
13: 27542750-27475753
Physical location of FLT3_Gene
Corpus Callosum Cistern
3q13.31
A chromosome band present on 3q
Xq11-q13
A chromosome band present on Xq
Dense connective tissue structures composed of collagen, elastic, reticular fibers, and smooth muscle cells. They are projections from the splenic capsule into the parenchyma. The arrangement of the fibers permits the spleen to expand passively and to serve as a small temporary reservoir for blood. The trabeculae which originate at the hilus contain and support trabecular arteries and veins which enter and leave the organ at the hilus. Trabeculae from other areas of the capsule do not contain vessels. Arteries branching out of the trabeculae are immediately surrounded by lymphocytes forming the white pulp.
Splenic Trabecula
Splenic Trabeculae
Parietal Layer of Bowman's Capsule
Parietal Layer of Bowman Capsule
Precentral Vermian Vein
A chromosome band present on 18q.
18q22.1
Laryngeal Mucosa
LYMPH NODE, MESENTERIC
Mesenteric Lymph Node
A lymph node located in the mesentery.
Superior Cervical Ganglion
A sympathetic ganglion located approximately at the first and second cervical vertebral levels.
15q21
A chromosome band present on 15q
Myometrium
The smooth muscle lining the uterus.
2q
Chromosome 2 Long Arm
Chromosome 2 Distal Arm
Distal (long) arm of chromosome 2
Pituitary Gland
Nervous System, Pituitary
Hypophysis Cerebri
Hypophysis
GLAND, PITUITARY
Pituitary
Pea-sized endocrine gland located at the base of the brain in the pituitary fossa. It produces and secretes hormones such as oxytocin and vasopressin, to regulate the activities of the hypothalamus.
Laryngopharynx
The lower part of the pharynx that connects to the esophagus.
Hypopharynx
The largest of the three paired salivary glands, located in front of the ear.
Parotid
GLAND, SALIVARY, PAROTID
Parotid Gland
Middle Temporal Gyrus
Middle Temporal Convolution
Chromosome 2 Proximal Arm
Chromosome 2 Short Arm
Proximal (short) arm of chromosome 2
2p
A chromosome band present on 15q
15q22
Olfactory Receptor Cells
A specialized, fusiform nerve cell with a large nucleus, embedded among the epithelial cells in the mucous membrane of the nose; it carries impulses from the olfactory receptors to the glomeruli in the olfactory bulb.
Olfactory Receptor Cell
Spinal Dorsal Nerve
Pulmonary Sinus
Sinus of Valsava
Lateral Ligament
Broad Ligament
A broad fold of peritoneum that extends from the side of the uterus to the wall of the pelvis. (MeSH)
Azygos Lobe
Accessory Lobe of Right Lung
A small lobe sometimes found on the upper part of the right lung, formed by an infolding of the pleura and separated from the rest of the upper lobe by a deep groove lodging the azygos vein.
A chromosome band present on 3q.
3q13.33
Amino Acid Sequence
The sequence of amino acids along a polypeptide chain.
Primary Protein Structure
Protein Sequence
Nasal Mucus
Gastrointestinal System Part
17: 31353125-31348777
Physical location of CCL15_Gene
Ileal Vein
A chromosome band present on 12p
12p13-p12
Peripheral B-Lymphocyte
A mature B-lymphocyte outside the bone marrow. It may be in the general circulation or in lymphatic tissue.
Premedullary Cistern
11p15.1-p14
A chromosome band present on 11p
15q23
A chromosome band present on 15q
Cytoplasmic
That portion of the cell contained within the plasma membrane but excluding the nucleus.
Cytoplasm
Canal of Hering
Physical location of DRD5_Gene
4: 9459872-9461902
Ligamentum Flavum
Skin of the Upper Limb and Shoulder
Skin of Upper Limb and Shoulder
Nucleolar Granular Material
Pars Granulosa
A collection of preribosomes in the nucleolus.
Axillary Tail of Breast
Axillary Tail of the Breast
Hymen
Thin membranous tissue that surrounds the vaginal opening.
Bladder Urothelial Cell
An epithelial cell, found in the bladder, originally thought to represent a transitional form between stratified squamous and columnar epithelial cells. In the contracted condition the epithelium consists of many cell layers, whereas in the stretched condition usually only two layers of cells can be distinguished.
Bladder Transitional Cell
Inferior Vermian Artery
Circular Fold
Valve of Kerckring
A chromosome band present on 1p
1p32.3
A projection of a neuron that conducts electrical impulses away from the neuronal cell body.
Axon
Nerve Fiber
Lumbar Artery
Inferior Internal Articular Artery
Connective tissue in which the fibrous component predominates. The cells, ground substance, and tissue fluid represent a minor component.
Dense Connective Tissue
Semitendinosus
External Pyramidal Cell Layer of the Cerebral Cortex
The third layer of the cerebral cortex, composed of an inner zone of medium sized pyramid-shaped cells with a single apical dendrite extending outward toward the surface and several dendrites extending inward and an outer zone of larger pyramid shaped cells whose dendrites and axons extend beyond this layer.
Medium Pyramidal Cell Layer
Outer Pyramidal Cell Layer
External Pyramidal Cell Layer
A chromosome band present on 15q
15q24
Tentorial Notch
Posterior Supratentorial Cistern
Subcardinal Vein
Chromosome 19 Physical Location
A chromosome band present on 2p
2p22-p21
Striped gray and white matter consisting of the neostriatum and paleostriatum (globus pallidus). It is located in front of and lateral to the thalamus in each cerebral hemisphere. The gray substance is made up of the caudate nucleus and the lentiform nucleus. The white matter is the internal capsule. (MeSH)
Corpus Striatum
Striate Body
Striate Nucleus
Striatum
Upper Extremity Part
Lateral Horn of the Spinal Cord
A cell of the parathyroid gland that has condensed chromatin in a small round nucleus. Its cytoplasm is composed of tightly packed mitochondria and glycogen granules, with rare secretory granules, stains pink, and the margin is usually observed.
Parathyroid Gland Oxyphil Cell
Parathyroid Gland Oxyphilic Cell
Tip of Tongue
Apex of Tongue
Tip of the Tongue
Apex of the Tongue
The anterior extreme of the tongue which can be made pointed for sensing or probing and which rests against the lingual aspect of the incisor teeth.
12: 56447151-56442386
Physical location of CYP27B1_Gene
9q33-q34
A chromosome band present on 9q
17q11
A chromosome band present on 17q
Brodmann's Area
One of 47 numbered regions within a map of the cerebral cortex. Each is characterized by a particular cell organization and also corresponds to a particular cortical function.
A chromosome band present on 15q
15q25
Foliate Papilla
5q33-q35
A chromosome band present on 5q
The posterior one third of the tongue behind the terminal sulcus that forms the anterior aspect of the oro-pharynx responsible for swallowing and modification of the voice in speech.
Base of the Tongue
Posterior Tongue
Base of Tongue
Subclavian Artery
ARTERY, SUBCLAVIAN
An artery located below the clavicle that supplies blood to the head and the arms. The right subclavian artery originates from the brachiocephalic artery and the left subclavian artery originates from the aortic arch.
9q22.3
A chromosome band present on 9q
Sphincter Pupillae Muscle
Physical location of CDKN2B_Gene
9: 21999312-21992903
Physical location of LTB_Gene
6: 31658181-31656314
Physical location of HOXC6_Gene
12: 52697103-52710865
A cell of the embryonic mesonephric duct. This duct connects the primitive kidney and urogenital sinus. In the presence of testosterone, it develops into the sperm collecting apparatus - epididymis, the vas deferens, and seminal vesicles. Without testosterone, it becomes vestigial.
Wolffian Duct Cell
Peroneal Artery
A chromosome band present on 15q
15q26
Mobilized Peripheral Blood Stem Cell
Blood stem cells found in the circulation after being stimulated to leave the bone marrow, usually by treatment with a cytokine or other drug.
12: 66839770-66834816
Physical location of IFNG_Gene
Myoid Portion of the Inner Segment of the Photoreceptor Cell
A simple epithelial cell that is shaped like a short column.
Low Columnar Cell
Sensory-Somatic Nervous System
4q12-q13
A chromosome band present on 4q
20: 1823425-1868537
Physical location of PTPNS1_Gene
Bone Matrix
Activated Mature Cytotoxic T-Lymphocyte
A white blood cell that is derived from a lymphocyte stem cell matured in the thymus and characterized by a CD8 marker on the surface and an antigen-specific T cell receptor which recognizes antigens in the context of MHC class I.
The inner most portion of the prostatic parenchyma surrounding the mid and proximal portions of the prostatic urethra where the ejaculatory ducts enter the urethra.
Periurethral Zone of the Prostatic Parenchyma
Sigmoid Flexure
Sigmoid Flexure of Colon
Sigmoid Flexure of the Colon
Methyl Group
11: 2116578-2110532
Physical location of IGF2_Gene
11q13.1
A chromosome band present on 11q
A chromosome band present on 9q
9q22.1
Parapeduncular Cistern
Lateral Supratentorial Cistern
Physical location of E2F1_Gene
20: 31737854-31727150
5q12
A chromosome band present on 5q
Recurrent Artery of Heubner
A large, irregular, quadrilateral area of bone found at the neck of the femur.
Great Trochanter
Base of the Skull
Base of Skull
Curved Tube
An anterior ethmoidal artery branch that supplies the meningeal tissues in the anterior fossa of the cranium.
Anterior Meningeal Artery
Muscle Spindles
The Muscle Spindle is composed of intrafusal fibers that are located within and run parallel to the extrafusal fibers of skeletal muscle. When the extrafusal fibers are stretched, the intrafusal fibers of the spindle stretch as well. When stretching occurs, the sensory neuron from the muscle spindle signals the motor neurons located within the ventral horn of the spinal cord. This signal causes the motor neurons to fire, resulting in contraction of the muscle. This reflex arc provides negative feedback. The muscular contraction induced by the stretching works against or negates further muscle stretch. This mechanism helps to maintain proper muscle tension or tone. Although the muscle spindle helps to maintain proper muscle tension, unlike the Golgi tendon organ, it is not an indicator of muscle tension, but rather of muscle length.
Muscle Spindle
The layer of cells that lines the arterial system.
Arterial System Endothelium
Stapedial Artery
Physical location of FCGR3B_Gene
1: 158332614-158325768
T7 Vertebra
The seventh thoracic vertebra counting from the top down.
Semispinalis Thoracis
6p21.33
A chromosome band present on 6p
Endometrioid Stromal Cell
Prostatic Glandular Tissue
Human Prostatic Glandular Tissue
The main section of the digestive tube that connects the esophagus to the small intestine.The body proper excludes the upper and lower sections of the fundus and pyloric portion respectively.
Body of Stomach
11: 525550-522242
Physical location of HRAS_Gene
Z-DNA
zDNA
Z-DNA can be obtained for certain sequences such as CGCGCG by increasing the salt concentration of the solution containing the sample to 4 molar NaCl. Z-DNA is left-handed and the thinnest & tallest with a diameter of about 18 Angstrom. The sugar pucker is both C(3')-endo and C(2')-endo. In Z-DNA, the Watson-Crick base pairs are perpendicular to the helix axis. When examined from the top of the helix, bases are present throughout the matrix of the helix with no exclusive domains for either the bases or the backbone. At times the sugar phosphate backbone travels very close to the center of the helix, and the bases to the very edge of the helix.
A general term describing the three cellular components of blood (white blood cells, red blood cells, and platelets), all which are made in the bone marrow. (Lymphoma Information Network Glossary)
Blood Cells
Blood Cell
Peripheral Blood Cell
5q13
A chromosome band present on 5q
ARTERY, ILIAC
Iliac Artery
A branch of the abdominal aorta that supplies blood to the lower trunk and the legs.
Lymphatic Capillary
Tiny vessels with porous walls that join to form the lymphatic vessels.
Vertebral Canal
Spinal Canal
Physical location of IL1R1_Gene
2: 102228920-102254852
A cell that splits off from the inner cell mass of the blastocyst and becomes part of the primitive yolk sac, which in non-mammals nourishes the embryo during development.
Yolk Cell
Parotidoauricular
Neural Groove
EXO I Motif
EXO I Domain
A conserved amino acid sequence (Asp-X-Glu) in DNA polymerases that is required for 3' > 5' exonuclease activity.
Dorsal Foot Interosseous Muscle
11q13.3
A chromosome band present on 11q
Connective Tissue Proper
Mesenteric Vein
One of two veins (inferior or superior) that returns deoxygenated blood from the intestines.
VEIN, MESENTERIC
Physical location of ERBB4_Gene
2: 213228793-212072321
Carotid Cistern
Epiglottic
A small cartilagenous flap-like valve that closes over the larynx during swallowing to prevent food entering the lungs.
Epiglottis
Retinal Vein
Physical location of CHRM5_Gene
15: 32097720-32144579
The roof or dome of the skull.
Calvarium
Skullcap
6p21.31
A chromosome band present on 6p
Superficial Circumflex Iliac Artery
2p16-p21
A chromosome band present on 2p.
A nephrogenic rest found within the renal lobe.
Intralobar Nephrogenic Rest
11: 67107862-67110699
Physical location of GSTP1_Gene
A chromosome band present on 11q
11q13.2
Axis of the Vertebra
C2 Vertebra
The second of the seven cervical vertebrae.
Physical location of CCL20_Gene
2: 228504075-228507755
5q11
A chromosome band present on 5q
S2 Vertebra
A ball-and-socket joint between the head of the femur and the acetabulum.
Hip Joint
Coxofemoral Joint
JOINT, HIP
Immunoglobulin Constant Region
The portion of an antibody that is invariant within a class of immunoglobulins. It is comprised of the carboxyl terminal half of both light chains and at least three quarters of each heavy chain starting from the carboxyl terminus and excludes the variable regions of the heavy and light chains.
A chromosome band present on 3q
3q13
Stratum Papillare
Foot Digit 1 Phalanx
12p12
A chromosome band present on 12p
Undersurface of the Frontal Lobe
16q
Chromosome 16 Long Arm
Chromosome 16 Distal Arm
Distal (long) arm of chromosome 16
A radiation field that includes the bilateral cervical, supraclavicular, and axillary lymph nodes.
Minimantle Field
Minimantle
Minimantle Radiation Field
Diagonal Branch of the Anterior Descending Artery
Ischium
The most posterior and ventral bone making up the pelvis.
Hip
11q24.1-q24.3
A chromosome band present on 11q
Ulnar Artery Branch
B-Immunoblast
A B-lymphocyte that has been transformed (activated) in response to antigenic stimulation.
Physical location of AREG_Gene
4: 75675888-75685761
Collateral Sulcus
Other Anatomic Concept
Other Anatomy Concept
A chromosome band present on 5q
5q31
Chromosome 5q31
Lower Extremity
The limb that is composed of the hip, thigh, leg and foot.
Hindlimb
LIMB, LOWER
Lower Limb
Primitive Node
Nasus Externus
External Nose
An oval body that is located in a tongue papilla and occupies the entire thickness of the epithelium. It is composed of neuroepithelial (sensory) cells, supporting cells, and basal cells. The opening at the apex of the taste bud is called taste pore.
Taste Bud
Physical location of MMP1_Gene
11: 102174104-102165861
16: 80656364-80689638
Physical location of HSD17B2_Gene
Physical location of BCAS4_Gene
20: 48844975-49827121
Processus Cochleariformis
Chorionic Plate
A chromosome band present on 14q
14q32
Transcriptional Activation Domain
A DNA-binding domain binds to a specific DNA sequence and a transcriptional activation domain interacts with the basal transcriptional machinery. An association of a transcriptional activation domain with a DNA-binding domain promotes the assembly of RNA polymerase II complexes at the TATA box and increase transcription. (NCI)
Reticular Dermis
The lower portion of the dermis beneath the papillary dermis. It is composed of thick collagen fibers.
X: 69136812-69169146
Physical location of IGBP1_Gene
Foot Digit 5 Phalanx
One of the two stem cells derived from hematopoietic stem cells. (MeSH)
Bone Marrow Myeloid Stem Cell
Stem Cells, Myeloid
Myeloid Progenitor Cells
Myeloid Progenitor Cell
Gastrophrenic Ligament
Physical location of BMPR1A_Gene
10: 88506376-88674925
Right Ovary
Head and Neck, Pharynx
A hollow tube that starts posterior to the mouth and nasal cavity and ends superior to the trachea and esophagus.
Pharynx
Cystic Vein
11q23
A chromosome band present on 11q
Chromosome 11q23
19: 46189044-46216141
Physical location of CYP2B6_Gene
Neuroepithelial Tissue
Tissue composed of neuroepithelial cells. The latter include astrocytes, oligodendrocytes, ependymal cells, neuroblasts, and olfactory receptor cells.
Tonsillohemispheric Artery
11q13.4
A chromosome band present on 11q
17q24-q25
A chromosome band present on 17q
Sternal Manubrium
The upper segment of the sternum, quadrangular in shape, as well as wider superiorly and narrower inferiorly. The sternal manubrium articulates with the clavicle and first two ribs.
A chromosome band present on 20p
20p11.2
The tissue separating adjacent alveolar air spaces.
Alveolar Septal Wall
Interalveolar Septum
Alveolar Septum
Respiratory Bronchiole Epithelium
Physical location of HOXA10_Gene
7: 26993083-26983451
A chromosome band present on 12p
12p13
A chromosome band present on 4q
4q26-q32
A chromosome band present on 11q
11q22
16p
Proximal (short) arm of chromosome 16
Chromosome 16 Short Arm
Chromosome 16 Proximal Arm
Bulbomembranous Urethra
Tooth Pulp
Dental Pulp
A richly vascularized and innervated connective tissue of mesodermal origin contained in the central cavity of a tooth and delimited by the dentin. It has formative, nutritive, sensory, and protective functions.
A chromosome band present on 11q
11q13.5
Stapes
Temporal Vein
Chromosome 21 Physical Location
Subclavius
A chromosome band present on 19q
19q13.2-q13.3
Cell Structure
The components of the cell and how they are arranged.
5q32
A chromosome band present on 5q
Embryonic Ear
Physical location of EVI1_Gene
3: 170346795-170285252
11: 44073675-44223556
Physical location of EXT2_Gene
An important supervisory center in the brain, rich in ganglia, nerve fibers, and synaptic connections. It is composed of several sections called nuclei, each of which controls a specific function. The hypothalamus regulates body temperature, blood pressure, heartbeat, metabolism of fats and carbohydrates, and sugar levels in the blood. Through direct attachment to the pituitary gland, the hypothalamus also meters secretions controlling water balance and milk production in the female. The role of the hypothalamus in awareness of pleasure and pain is well established in the laboratory. It is involved in the expression of emotions, such as fear and rage, and in sexual behaviors. Despite its numerous vital functions, the hypothalamus in humans accounts for only 1/300 of total brain weight, and is about the size of an almond. Structurally, it is joined to the thalamus; the two work together to monitor the sleep-wake cycle.
Hypothalamus
BRAIN, HYPOTHALAMUS
Physical location of AZU1_Gene
19: 778831-783017
Gray matter located in the dorsomedial part of the medulla oblongata associated with the solitary tract. The solitary nucleus receives inputs from most organ systems including the terminations of the facial, glossopharyngeal, and vagus nerves. It is a major coordinator of autonomic nervous system regulation of cardiovascular, respiratory, gustatory, gastrointestinal, and chemoreceptive aspects of homeostasis. The solitary nucleus is also notable for the large number of neurotransmitters which are found therein. (MeSH)
Nucleus of the Solitary Tract
Nucleus of the Tractus Solitarius
Nucleus Tractus Solitarius
Solitary Nucleus
Chromosome 2
The designation for each member of the second largest human autosomal chromosome pair. Chromosome 2 spans more than 237 million base pairs and represents almost 8% of the total DNA in normal diploid cells.
A space inside the uterus lined by a layer of mucus membranes called the endometrium.
Endometrial Cavity
Cervical Neck Region
An enteroendocrine cell located in the basilar portions of the glands of the gastrointestinal tract. The granules in the cell stain readily with chromium and silver salts without pretreatment with a reducing agent.
Argentaffin Cell
A chromosome band present on 9p
9p21.2
A chromosome band present on 9q
9q13
The outermost and largest muscle of the buttocks.
Gluteus Maximus
Reticular Cell
A cell with processes making contact with those of other similar cells to form a cellular network sheathing a network of reticular fibers, which constitutes the stroma of all lymphoid organs except the thymus
Reticular Cells
Part of the chromosome bands present on the short (p) arm of chromosome 2.
2p25.1
Physical location of CLC_Gene
19: 44920508-44913736
Ruffini's Ending
Ruffini's Corpuscle
Ruffini Corpuscle
The membranes that envelop and protect the brain.
Cerebral Meninges
A chromosome band present on 1p
1p31.2-p31.1
The designation for each member of the largest human autosomal chromosome pair. Chromosome 1 spans about 247 million nucleotide base pairs and represents about 8% of the total DNA in normal diploid cells.
Chromosome 1
9p21.3
A chromosome band present on 9p
Conus Medullaris
Chordae Tendineae
Tendons that connect the papillary muscles to the tricuspid valve and mitral valve.
Periocular Region
A sympathetic ganglion located at the seventh cervical vertebral level.
Inferior Cervical Ganglion
A chromosome band present on 11q
11q14.2-q22.3
Brain Dura Mater
Posterior Communicating Artery
A chromosome band present on 2p
2p25.3
Circumflex Iliac Artery
Crystal of Reinke
Auricular Vein
A vein located in the ear region. It may pertain to the anterior or posterior auricular veins.
VEIN, AURICULAR
Semicircular Canal
Inner Wall of the Vestibule
External Iliac Vein
A right-handed spiral conformation; the a-helix has a pitch of 5.4 A and has 3.6 amino acid residues per turn; every main chain C=O and N-H group is hydrogen-bonded to a peptide bond 4 residues away; the peptide planes are roughly parallel with the helix axis and the dipoles within the helix are aligned, i.e. all C=O groups point in the same direction and all N-H groups point the other way; side chains point outward from helix axis and are generally oriented towards its amino-terminal end. (from expasy.org)
Alpha Helix
Chromosome 6
The designation for each member of the sixth largest human autosomal chromosome pair. Chromosome 6 spans more than 170 million base pairs and represents between 5.5 and 6% of the total DNA in normal diploid cells.
Glomerulosa Zone
Superficial Cervical Artery
granular leukocyte
Granulocytic
Granular Leukocytes
Granulocytes
Granulocyte
Granulocytic cell
Blood granulocytic cell
A leucocyte with conspicuous cytoplasmic granules. In humans the granulocytes are also classified as polymorphonuclear leucocytes and are subdivided according to the staining properties of the granules into eosinophils, basophils and neutrophils.
Eosinophil Precursor Cell
Physical location of ACVR2_Gene
2: 148436296-148519244
Deep Middle Cerebral Vein
Cranial Cavity
BODY CAVITY, CRANIAL
The atrium that is formed by the bones of the skull and containing the brain.
Cervix Glandular Epithelium
Posterior Choroidal Artery
Physical location of CCL11_Gene
17: 29636800-29639312
Inferior Rectus Muscle
Methylation Site
A sequence in DNA that can be recognized by a specific methylase enzyme and that contains the specific base target for methyl transfer.
Methylase Recognition Site
DNA Methylation Site
Postganglionic Parasympathetic Fiber
Nerve fibers which project from parasympathetic ganglia to synapses on target organs. Parasympathetic postganglionic fibers use acetylcholine as transmitter. They may also release peptide cotransmitters. (MeSH)
Parasympathetic Fibers, Postganglionic
The lateral white column of the spinal cord between the lines of exit and entrance of the anterior and posterior nerve roots.
Antero-Lateral Column
Chromosome 5
The designation for each member of the fifth largest human autosomal chromosome pair. Chromosome 5 spans about 181 million base pairs and represents almost 6% of the total DNA in normal diploid cells.
Hair Follicle Infundibulum
A chromosome band present on 4q
4q13.1-q21.1
Left Superomedial Segment
Couinaud segment IVa, corresponding to the medial segment of the left lobe of the liver, located superiorly.
Couinaud Segment IVa
Epithelial Cell Junction
A region of cell-cell contact between adjacent cells in an epithelial layer.
Blastomere
Blastocytes
Embryo stage 2
Blastomeres
The undifferentiated cells formed by cleavage of the fertilized ovum. This includes cells in the cleavage, morula, and blastula stages of the embryo. (MeSH)
Neck of Tooth
Neck of the Tooth
Collum Dentis
BRAIN, THALAMUS
Dorsal Thalamus
Thalamus
An ovoid mass composed predominantly of gray substance and associated laminae of white substance. The thalamus is divided into anterior, medial, and lateral parts. The function of the thalamus is to relay sensory impulses and cerebellar and basal ganglia projections to the cerebral cortex. The thalamus is positioned within the posterior part of the diencephalon forming most of each lateral wall of the third ventricle.
SINES
SINE
Short Interspersed Element
SINEs. Short, 100-300 bases long, highly repeated sequences which contain RNA polymerase III promoters. The primate Alu and the rodent B1 SINEs are derived from 7SL RNA, the RNA component of the signal recognition particle. Most other SINEs are derived from tRNAs including the MIRs (mammalian-wide interspersed repeats).
Peroneus Longus
12: 54646826-54652835
Physical location of CDK2_Gene
Splenium of the Corpus Callosum
UBA domains are a commonly occurring sequence motif of approximately 45 amino acid residues that are found in diverse proteins involved in the ubiquitin/proteasome pathway, DNA excision-repair, and cell signaling via protein kinases. The human homologue of yeast Rad23A is one example of a nucleotide excision-repair protein that contains both an internal and a C-terminal UBA domain.
Ubiquitin-Associated Domain
UBA Domain
Meniscus
A crescent-shaped wedge of cartilaginous material that serves as a cushion in the knee, between the tuberosities of the femur and the tibia. There are two locations, the medial meniscus located on the inner aspect of the knee and the lateral which is located on the outer aspect.
Constrictor Vulvae
OROPHARYNX
Tissue that occupies the area between the soft palate and upper portion of the epiglottis.
Oropharyngeal Tissue
Posterior Olfactory Lobule
Anterior Perforated Space
A thin fenestrated layer of the pars nervosa retinae adjacent to the outer nuclear layer and through which extend the visual rods and cones.
Outer Limiting Membrane
Chromosome 10 Physical Location
The part of the brain that connects the cerebral hemispheres with the spinal cord. It consists of the mesencephalon, pons, and medulla oblongata.
Brain Stem
BRAIN, BRAIN STEM
Brainstem
Any of various funnel-shaped parts of the body.
Infundibular
Infundibulum
Deep Femoral Artery
Profunda Femoris
Chromosome 4
The designation for each member of the fourth largest human autosomal chromosome pair. Chromosome 4 spans more than 186 million base pairs and represents between 6 and 6.5% of the total DNA in normal diploid cells.
External Abdominal Ring
Physical location of IL4_Gene
5: 132037272-132046267
Physical location of IL3RA_Gene
X: 1499188-1545409
Physical location of RALGDS_Gene
9: 133026115-133002662
Toe
One of the terminal digits of the foot.
S5 Vertebra
Sternothyroid
Physical location of KITLG_Gene
12: 87476713-87393065
gland of Lieberkuhn
colon crypt
Crypt of Lieberkuhn
2: 208220192-208289079
Physical location of CREB1_Gene
Mediastinum
A group of organs surrounded by loose connective tissue, separating the two pleural sacs, between the sternum anteriorly and the vertebral column posteriorly as well as from the thoracic inlet superiorly to the diaphragm inferiorly. The mediastinum contains the heart and pericardium, the bases of the great vessels, the trachea and bronchi, esophagus, thymus, lymph nodes, thoracic duct, phrenic and vagus nerves, and other structures and tissues.
Chromosome 3
The designation for each member of the third largest human autosomal chromosome pair. Chromosome 3 spans almost 200 million base pairs and represents about 6.5% of the total DNA in normal diploid cells.
The glandular portion of the salivary system whose combined secretions constitute the saliva; a clear, alkaline, somewhat viscus secretion that keeps the mouth moist and aids in swallowing and digesting food. It includes the major salivary glands - sublingual, submandibular, and parotid glands, as well as numerous minor glands.
Acinar Salivary Gland System
Physical location of FZD2_Gene
17: 39990451-39992433
External Intercostal Muscle
Ischiocavernosus
Tongue Muscle
Motor neurons which activate the contractile regions of intrafusal muscle fibers, thus adjusting the sensitivity of the muscle spindles to stretch. (MeSH)
Neurons, Fusimotor
Motor Neurons, Gamma
Motor Neurons, Gamma-Efferent
Gamma Motor Neuron
Trapezoid Bone
Trapezoid
Lesser Multiangular Bone
A carpal bone located between the trapezium and capitate bones.
Rostrum of the Corpus Callosum
5: 35892748-35912681
Physical location of IL7R_Gene
The line between the simple columnar epithelium of the rectum and the stratified epithelium of the anal canal.
Pectinate Line.
Anocutaneous Line
BIR Domain
Containing perfectly conserved histidine and cysteines residues. the BIR domain is about 70 residues long arranged in tandem repeats separated by a linker of variable length. Found in IAP (Inhibitor of Apoptosis Protein) Family proteins, it seems to confer cell death-preventing activity. Except NAIP, family members typically contain two or three BIR repeats and a C-terminal RING finger. A second group of BIR-domain-containing proteins (BIRPs) include mammalian Bruce and Survivin proteins, as well as BIR-containing proteins in yeasts and C. elegans. Survivin-like BIRPs regulate cytokinesis and mitotic spindle formation. (NCI)
Inhibitor of Apoptosis Domain
BIR Motif
IAP Repeat
Baculovirus Inhibitor of Apoptosis Protein Repeat
Primordium of the Heart
Primordium of Heart
A chromosome band present on 2p
2p14-p13
Non-Articular Bone Surface
A region of the brain at the junction of the pons, cerebellum, and medulla. It is a frequent site of tumor formation.
Cerebellopontine Angle
Lateral Lenticulostriate Artery
Interphase Chromosome
Interphase chromosomes are decondensed chromosomes that reside in the interphase nucleus in the form of chromatin. Two types of chromatin, euchromatin and heterochromatin, can be discerned microscopically.
Cardiac Nerve Plexus
A mucus-producing epithelial cell lining the endocervical lumen.
Endocervical Columnar Cell
The portion of an integral membrane protein crossing through the plasma lemma (cell membrane) or that of an internal vesicle. This region is highly hydrophobic, approximately 20 amino acids long, and bordered by charged amino acids.
TM Domain
Transmembrane Region
Transmembrane Domain
Physical location of BAI1_Gene
8: 143542379-143623370
ITIM
ITIM (immunoreceptor Tyr-based inhibition motif) (I/V-X-Y-X-X-L), a protein domain involved in STP, binds to SH2 domain in SHP1 and SHP2, e.g., in KIR family.
Immunoreceptor Tyrosine-Based Inhibitory Motif
Physical location of AVPR1B_Gene
1: 202767011-202774706
8q24.12-q24.13
A chromosome band present on 8q
A chromosome band present on 3p
3p21.3-p21.2
Orifice of the Ureter
Ureteric Orifice
Plantar
The undersurface of the foot.
Plantar Region
Perimysium
Iliac Vein
Metacarpal Bone
Any of the five bones between the wrist and the fingers that form the skeleton of the palm.
Os Metacarpale
Metacarpal
Metacarpal Bones
Gastric Acid
Greater Tuberosity
A part of the lower limb, located between hip and knee.
Thigh
Basal Cell of the Squamous Epithelium
Physical location of CREB3_Gene
9: 35722317-35727005
Embryonic Digestive System
The designation for each member of the ninth largest human autosomal chromosome pair. Chromosome 9 spans about 145 million base pairs of nucleic acids and represents between 4 and 4.5% of the total DNA in normal diploid cells.
Chromosome 9
The bone in the proximal row of carpal bones that lies between the scaphoid and triquetral bones.
Lunate
Semilunar Bone
Lunate Bone
THORACIC WALL
Chest Wall
The total system of structures outside the lungs that move as a part of breathing; it includes all structures from the skin to the parietal pleura.
A chromosome band present on 3p
3p21.3-p21.1
Striated Muscle Tissue Fiber
Striated Muscle Tissue Cell
Striated Muscle Cell
A cylindrical multinucleated cell containing contracting myofibrils, across which run transverse light and dark areas, enclosed in a delicate plasma membrane.
11q24
A chromosome band present on 11q
Female Urethra
Longissimus Cervicis
Intercalated Duct Cell
Terminal Duct Cell
Physical location of F9_Gene
X: 138228415-138371137
Lymphocyte
White blood cells formed in the body's lymphoid tissue. The nucleus is round or ovoid with coarse, irregularly clumped chromatin while the cytoplasm is typically pale blue with azurophilic (if any) granules. Most lymphocytes can be classified as either T or B (with subpopulations of each); those with characteristics of neither major class are called null cells.
lymph cell
Lymphocytes
Posterior Lobe of Human Prostate
PROSTATE GLAND, POSTERIOR LOBE
The prostate gland lobe that is located on the posterior side of the organ.
Posterior Lobe of the Prostate
Chromosome 8
The designation for each member of the eighth largest human autosomal chromosome pair. Chromosome 8 spans about 145 million base pairs and represents between 4.5 and 5.0% of the total DNA in normal diploid cells.
A chromosome band present on 14q
14q31
Atlanto-Occipital Joint
The joint located between the atlas and occipital vertebrae.
The organ of hearing located on the right side of the head.
Right Ear
A chromosome band present on 1p
1p36.1-p35
Physical location of GALR2_Gene
17: 71582487-71585168
Periosteum
The outer membrane that surrounds a bone. It contains connective tissue, capillaries, nerves, and a number of types of cell, including osteoclasts. The periosteum plays an important role in bone repair and growth.
Short Saphenous Vein
Physical location of GRAP_Gene
17: 18890997-18865810
Activated Lymphocyte
A white blood cell that, after being in contact with an antigen, rearranges its DNA to defend against that one specific type of antigen. After activation, it can then proliferate and differentiate into memory cells, antibody-secreting cells or plasma cells.
specific immune cell
BODY CAVITY, ABDOMINAL
Abdomen
The portion of the body that lies between the thorax and the pelvis.
Abdominal Cavity
External Malleolar Artery
A chromosome band present on 9q.
9q33.3
Tensor Fasciae Lata
Optic Tract
Physical location of EMP1_Gene
12: 13240924-13260975
4: 40021168-40068421
Physical location of ARHH_Gene
Physical location of IL13_Gene
5: 132021764-132024700
A slender or elongated structure that supports another usually larger structure.
Stalk
Phrenic Vein
Semicircular Duct
The designation for each member of the seventh largest human autosomal chromosome pair. Chromosome 7 spans more than 158 million base pairs and represents between 5 and 5.5% of the total DNA in normal diploid cells.
Chromosome 7
Orifice of Human Prostatic Duct
Physical location of HTATIP_Gene
11: 65236065-65243651
Splenic Capsule
Physical location of DRD4_Gene
11: 627305-630703
Right Subcostal Vein
Sacroiliac Joint
The joint located between the sacrum and the ilium.
Thalamencephalon
Inter Brain
Inter-brain
Inferior Profunda Artery
Montgomery's Tubercles
Montgomery's Tubercle
A group of small sebaceous glands that secrete into the areolae of the mother's breast to lubricate the nipple during breastfeeding.
Montgomery Tubercle
20S Proteasome
The 20S proteasome, as proteolytic core of the proteasome system, is essential in ATP dependent ubiquitin protein complex degradation and in antigen processing in antigen presenting cell. It has 13-15 subunits each of which has three or four different peptidase activities. 26S proteasomes may be formed in an ATP dependent fashion from a 20S proteasome and additional components, CF1 (660 kD), CF2 (250 kD) and CF3 (600 kD). The 20S proteasome interacts with additional subunits, PA700 and PA28, to form an ATP-dependent multicatalytic proteinase complex (MPC) involved in the ATP ubiquitin degradation pathway.
20S Core Proteasome
20S Catalytic Proteasome
20S Proteosome
Lower Jaw Tooth
Any of the teeth located in the mandible.
Physical location of USF1_Gene
1: 157825530-157822115
External Iliac Artery
Glisson's Sphincter
Oddi's Sphincter
The muscle fibres around the opening of the common bile duct (ductus choledochus) into the duodenum at the papilla of Vater.
Sphincter of Oddi
C-Cell
C cell
Parafollicular Cell
A neuroendocrine cell found in the thyroid gland interspersed among the follicular cells or in clusters between the follicles. It produces and secretes calcitonin in response to its calcium receptor.
A lipid with 2 fatty acid chains attached to a carbohydrate-containing head group that is found on the outer leaflet of the plasma membrane.
Plasma Membrane Glycolipid
1q
Chromosome 1 Long Arm
Chromosome 1 Distal Arm
Chromosome 1q
Distal (long) arm of chromosome 1
Azurophilic Granule
A cytoplasmic granule found in the myelocyte lineage that can be stained with azure dyes.
A chromosome band present on 1q
1q24.2
Fifth Pharyngeal Pouch
7q31.3
A chromosome band present on 7q
Xq27.1-q27.2
A chromosome band present on Xq
Posterior Tibial Vein
Spicule
A tiny, needle-like structure.
Spicular
Membrane of Crista
The part of the inner mitochondrial membrane that folds inward to enclose the cristae.
Muscles of the lower back whose actions involve the flexion of the hips and lumbar spine. The term may refer to psoas major muscle and psoas minor muscle, both located in the lower back.
Psoas Muscle
MUSCLE, PSOAS
A chromosome band present on 3q
3q21
A chromosome band present on Xp
Xp11.21-p11.22
Malpighian Capsule
Bowman's Capsule
Bowman Capsule
12: 56432431-56428270
Physical location of CDK4_Gene
Stratified epithelium that changes shape from cuboidal to squamous when stretched without losing strength or consistency. This type of epithelium is found in the urinary tract.
Transitional Epithelium
Antero-Lateral Ascending Tract
The nervous tract that carries pain, temperature, and tactile signals from the periphery to the brain.
10q23.33
A chromosome band present on 10q
A lymphocyte derived most often from a pre-germinal center B cell, less often from a post-germinal center B cell. It is characterized by an abundant pale cytoplasm, indented nuclei with inconspicuous nucleoli, and open chromatin. It is found in the marginal zones of lymph nodes adjacent to the subcapsular and intermediary sinuses.
Monocytoid B-Cell
Monocytoid B-Lymphocyte
Body of the Lateral Ventricle
Remnant
An embryonic structure that remains after the completion of the embryonic development of an organ or system.
Right Lung Respiratory Bronchiole
16: 31274010-31301819
Physical location of ITGAX_Gene
N-Domain
N Domain
N Domain is one of the seven predicted immunoglobulin-like domains that members of the CEA family protein have. It is extremely hydrophobic. (From OMIM and NCI)
Physical location of C5_Gene
9: 120892108-120794170
The area of the body below the ribs and above the hipbones.
Lumbar Region
A chromosome band present on 1q.
1q24.3
A tubular structure that runs from the middle ear to the nasopharynx and is approximately 3-4 cm length. Its lumen is roughly triangular and has average diameter of 2-3 mm. The lumen is lined by ciliated pseudostratified, columnar epithelium, which sweeps material from the middle ear to the nasopharynx. It is functionally collapsed at rest, with slight negative pressure present in the middle ear, and opens during swallowing, sneezing, and yawning. It serves to ventilate pressure differences between the middle ear and nasopharynx. This tube also allows middle ear secretions to drain into the nasopharynx.
Eustachian Tube
Tuba Auditoria
Auditory Tube
Pharyngotympanic Tube
Anatomic structures forming the upper respiratory tract and upper part of the digestive tract. They include the oral cavity, sinonasal tract, pharynx, pyriform sinus, larynx, trachea, and esophagus.
Aerodigestive Tract
A chromosome band present on 3p
3p11.2
Subcellular Anatomy
Cell Anatomy
Cellular Anatomy
Conjunctiva
A thin, transparent tissue divided into the palpebral conjunctiva (covering the inner side of the eye lid) and the bulbar conjunctiva (covering the eyeball).
Bladder Fundus
The portion of the bladder that is formed by the posterior wall and is located opposite to the bladder opening.
BLADDER, FUNDUS
Fundus of the Bladder
Extraglomerular Mesangial Cell
Mesencephalic Perforating Artery
7: 115733395-115742546
Physical location of CAV2_Gene
A crescent-like structure located in the upper and posterior surfaces of the testis. It consists of the efferent ductules and the duct of the epididymis. It facilitates the maturation of sperm that is produced in the testis.
Epididymis
Epididymal
Autonomic Nervous System
ANS
Autonomic
involuntary nervous system
The part of the nervous system of vertebrates that controls involuntary actions of the smooth muscles and heart and glands.
Used when the correct precoordinated combinations of areas is not listed.
Other Multiple Areas
Hormone Receptor DNA-Binding Domain
One of three structural motifs observed in DNA binding domains of zinc proteins. Originally identified in the glucocorticoid receptor, it's also known as the C4 zinc finger, or the zinc twist. Each of two zinc atoms is bound to four cysteine residues; the zinc twist is represented by a helical DNA recognition site located between the two zinc atoms.
Zinc Twist Motif
C4 Zinc Finger
7q31.1
A chromosome band present on 7q
External Lateral Ligament of the Ankle
External Lateral Ligament of Ankle
Ankle Lateral Collateral Ligament
Lateral Collateral Ligament of the Ankle
Lateral Collateral Ligament of Ankle
Physical location of EPO_Gene
7: 99963074-99965974
Vertebrae
Vertebra
Any of the ring-shaped bony structures that constitute the spinal column and surround the spinal cord.
Type 2 Helper Cell
Type 2 Helper Cells are a subset of helper-inducer T-lymphocytes which synthesize and secrete the interleukins IL-4, IL-5, IL-6, and IL-10. These cytokines influence B-cell development and antibody production as well as augmenting humoral responses.
Th-2 Cell
Th2 Cells
Th2 Cell
Mechanoreceptor Cell
Auditory Receptor Cell
1: 198708730-198716790
Physical location of ELF3_Gene
Urogenital Ridge
19: 3310616-3414603
Physical location of NFIC-Gene
Part of the chromosome bands present on the long (q) arm of chromosome 16.
16q24.1
26S ATP-Dependent Proteasome
Proteasomes are large multicatalytic proteolytic complexes found in all eukaryotic cells, and simpler forms have been found in archaebacteria and certain eubacteria. In eukaryotes, the 20S proteasome also exists as the central core of the 26S (2000 kDa) proteasome complex, which catalyzes the degradation of ubiquitin-conjugated proteins and contains an additional 19S complex, composed of regulatory proteins and six ATPases.
26S ATP-Dependent Protease
26S Proteasome Complex
26S Proteosome
Ganglion of Scarpa
Vestibular Ganglion
Dorsal Metatarsal Vein
Paranemin
External Iliac Artery Branch
A layer of areolar tissue beneath the mucous membrane
Submucosa
Extrahepatic Bile Duct Epithelium
Mitochondrial Matrix Granule
A detectable particle containing phospholipids, protein and calcium found in the mitochondrial matrix.
Paranasal Sinus Epithelium
Laryngeal Epithelium
Cremaster Muscle
Pubic Symphysis
The joint between the left and right pubic bones at the front of the pelvis.
Physical location of BIN1_Gene
2: 127581094-127521837
Uncus
4: 123102497-123096130
Physical location of CCNA2_Gene
19: 38485160-38482776
Physical location of CEBPA_Gene
Nonphotosensitive Region of the Retina
A chromosome band present on 8p
8p22-p11
A bony protrusion on the femoral bone to which muscles are attached.
Trochanter
4: 122975781-122946753
Physical location of ANXA5_Gene
2: 220262459-220265932
Physical location of INHA_Gene
Neural Canal
Physical location of FOXO1A_Gene
13: 40138734-40027817
Large, phagocytic mononuclear leukocytes produced in the vertebrate bone marrow and released into the blood; contain a large, oval or somewhat indented nucleus surrounded by voluminous cytoplasm and numerous organelles.
Monocyte
Marrow monocyte
Blood monocyte
Monocytes
Sensory Receptor of the Ear
A chromosome band present on 16q
16q22-q23.1
Chromosome 1p
Chromosome 1 Proximal Arm
Chromosome 1 Short Arm
1p
Proximal (short) arm of chromosome 1
A chromosome band present on 10q
10q24-qter
Somatotroph
Somatotrope Cell
GH Cell
Somatotroph Cell
An acidophil of the adenohypophysis that stains preferentially with orange G and secretes growth hormone.
SOCS Box Domain
The SOCS box is an approximately 40 amino acid region of homology invariably located at the C-terminus of the proteins in which it is present. Initially identified in the SOCS, or suppressors of cytokine signaling family of proteins, the SOCS box appears to be involved in targeting proteins for ubiquitination. The SOCS box contains a sub-domain known as the BC-box that is also found in the VHLa domain. The BC box in both SOCS box and VHLa domain facilitates binding to the Elongin BC complex. Elongin BC, in turn, interacts with the von-Hippel Lindau (VHL) tumor suppressor protein to form the core of the larger VCB E3 ubiquitin protein ligase complex. Thus, the SOCS box/VHLa domain may serve a function analogous to the structurally related F-box protein linking substrates to E3 complexes to allow ubiquitination. Five classes of N-terminal regions are found associated with the C-terminal SOCS box. (Pawson Lab, SLRI, Mount Sinai Hospital, 2003)
Dorsum of the Tongue
IAP
Intracisternal A-Particle
Retroviral-like intracisternal A particles. High copy number family of repeated elements in the mouse with a typical proviral organization. Expressed very early in mouse development (2-8 cell stage) and in transformed cells. Mutant alleles of various genes contain newly-integrated IAP genes.
Thoracodorsal Artery
Dorsal Thoracic Artery
Superior Palpebral Fold
Bronchus Submucosa
Dorsomedial Nucleus of the Thalamus
A lymphocyte found in the marginal zones of lymphoid tissues. It has a naive B lymphoid lineage and plays an important role in the early phases of immune response with its ability to rapidly differentiate into an antibody secreting cell. These cells can directly activate T cells, interact with other antigen presenting cells, transporting and concentrating antigen during the course of T-dependent and T-independent immune responses.
Marginal Zone B-Lymphocyte
Pharyngeal Muscle
Pharyngeal Muscles
The muscles of the pharynx, the inferior, middle and superior constrictors, salpingopharyngeus, and stylopharyngeus. (MeSH)
A chromosome band present on 16p
16p11.2-12.1
Right Internal Spermatic Artery
Right Testicular Artery
Right Spermatic Artery
Physical location of GTF3C2_Gene
2: 27478096-27460374
Aortic Arch
The curved section of the aorta between the ascending and the descending tracts. The brachiocephalic, left common carotid and left subclavian arteries branch from the aorta at this section.
11: 118433122-118420110
Physical location of HYOU1_Gene
Eyelid Connective Tissue
Tuberculum Sellae
A chromosome band present on 10q
10q23.31
Genito-Urinary Region
17q24.3-q25.1
A chromosome band present on 17q.
Angular Artery
Terminal branch of the facial artery with distribution to the side of the nose.
T-Lymphocytes, Suppressor-Inducer
T-Cells, Suppressor-Inducer
T-Lymphocyte, Suppressor-Inducer
Subpopulation of CD4+ lymphocytes which induce CD8+ suppressor T-cells to suppress antibody production by B-cells. They also stimulate other cellular immune responses. (MeSH)
Suppressor-Inducer T-Lymphocyte
Physical location of FOSB_Gene
19: 50663093-50670276
Olfactory Tract
Thoracic Vein
Superior Pancreatico-Duodenal Artery
A chromosome band present on 19q
19q12
17: 31369118-31364210
Physical location of CCL23_Gene
Cerebellar Cortex
Falx Cerebelli
Inhibitory Synapse
A synapse in which the firing of the presynaptic cell reduces the probability of firing of the postsynaptic cell.
Olfactory Chemoreceptor
Internal Granular Layer of the Cerebellum
Inner Granular Layer of the Cerebellum
21: 33619084-33653999
Physical location of IFNAR1_Gene
3q28
A chromosome band present on 3q
Patellar Ligament
The portion of the digestive canal between the pharynx and stomach. It is about 25 cm long and consists of three parts: the cervical part, from the cricoid cartilage to the thoracic inlet; thoracic part, from thoracic inlet to the diaphragm; and abdominal part, below the diaphragm to the cardiac opening of the stomach.
Gastrointestinal Tract, Esophagus
Esophagus
Bone of Upper Extremity
Bones of Upper Extremity
Bone of the Upper Extremity
A bone of the arm (upper extremity).
Ciliary Epithelium
Cell-Extracellular Matrix
Extracellular Matrix
The extracellular matrix is a network of fibers that hold cells together. It is found within the extracellular space and in association with the basement membrane of the cell surface. It promotes cellular proliferation and provides a supporting structure to which cells or cell lysates in culture dishes adhere. It is broken down during normal physiological and disease processes such as bone remodeling, embryogenesis, cancer, and arthritis.
A chromosome band present on 10q
10q11.2-q21
7: 147833581-147935850
Physical location of CUL1_Gene
Physical location of KLRD1_Gene
12: 10351684-10359227
Floor of Mouth
Floor of the Mouth
The area of the mouth under the ventral surface of the tongue.
A chromosome band present on 19q
19q13
Physical location of CASP9_Gene
1: 15596096-15564103
A chromosome band present on 1p
1p33-p34
22: 22453764-22501255
Physical location of SMARCB1_Gene
2: 206849840-206853158
Physical location of EEF1B2_Gene
10q22.1-q23
A chromosome band present on 10q
Epidermal Ridge
Rete Ridge
Epidermal Ridges
10: 103525817-103519877
Physical location of FGF8_Gene
Vaginal Plate
3q29
A chromosome band present on 3q
17: 23151682-23107920
Physical location of NOS2A_Gene
Lienal Artery
Splenic Artery
1: 158364633-158379375
Physical location of FCGR2C_Gene
Any structures that are enclosed within nucleus are considered nuclear structure, including any macromolecular structures. (NCI)
Nuclear Structure
Nucleoplasm
The nuclear contents other than the nucleolus.
Vermian Cistern
Renal tissue consisting of peritubular and periarterial spaces. The relative contribution of each of these two spaces to interstitial volume varies, but increases in size from the cortex to the papilla. In the cortex there is little interstitium because the peritubular capillaries occupy most of the space between the tubules. The cortical interstitial cells and outer medula consist mainly of fibroblastic cells and mononuclear cells. The inner medulla consists primarily of pericytes, lipid-laden cells and mononuclear cells arranged like rungs of a ladder.
Renal Interstitial Tissue
Gonadal Ridge
Medial Supraclavicular Lymph Nodes
Medial Supraclavicular Lymph Node
BH4 Domain
BH4 is present only in the amino-terminal regions of pro-survival family bcl-2 members and is essential for the anti-apoptotic function, although deletion of BH4 does not necessarily impair the ability of BH4-containing proteins to bind to a variety of other bcl-2-related proteins.
The central portion of the lymph node. It is divided into sections by tracts of lymphatic tissue called medullary cords. Between the medullary cords are the medullary sinuses, which consist mainly of macrophages that engulf microorganisms as part of the lymph node's filtering function. Lymphocytes and plasma cells are also found in the medullary portion.
Lymph Node Medullary Portion
The epithelium that lines the gastrointestinal tract.
Gut Epithelium
An elongated spindle-shaped contractile cell, peculiar to an involuntary muscle, containing a single nucleus and longitudinally arranged myofibrils.
Smooth Muscle Cell
Leiomyocyte
Smooth Muscle Tissue Cell
3q26
A chromosome band present on 3q
Third hypervariable region (V3) of the gp120 HIV envelope protein.
V3 Loop
V3 Loop of HIV-1
1: 189509828-189513060
Physical location of RGS2_Gene
A porelike structure surrounding the entire circumference of the anterior chamber through which aqueous humor circulates to the canal of Schlemm. (MeSH)
Trabecular Meshwork
Physical location of CD4_Gene
12: 6769005-6800235
An internal membrane structure of the eukaryotic cell. Biochemically similar to the rough endoplasmic reticulum, but lacks the ribosome binding function. Tends to be tubular rather than sheet like, may be separate from the rough endoplasmic reticulum or may be an extension of it. Abundant in cells concerned with lipid metabolism and proliferates in hepatocytes when animals are challenged with lipophilic drugs.
sER
Smooth-Surfaced Endoplasmic Reticulum
Smooth Endoplasmic Reticulum
Foramen Primum
Those vertebrae between the ribs and the pelvis, L1-L5 in man.
L Spine
Lumbar Spine
3q27
A chromosome band present on 3q
2p14.1
A chromosome band present on 2p
A chromosome band present on 1p
1p33-p31
12: 108896820-108830329
Physical location of GIT2_Gene
Ductus Venosus
Tooth 2
The upper right 2nd molar, as defined by the Universal tooth numbering system.
Female Genitalia
The external female sexual organs.
A chromosome band present on 10q
10q24.1-q25.1
Cerebral Fissure
3q24
A chromosome band present on 3q
6: 131991056-131936801
Physical location of CRSP3_Gene
Bronchiole
Bronchiolus
Bronchioles
Right Common Iliac Artery
Petrous Apex
A chromosome band present on 7q
7q11-q22
Foregut
Non-parameningeal Head and Neck Area
The superficial areas of head and neck including the oral cavity, buccal mucosa, and the parotid region.
7: 101521887-101555613
Physical location of APS_Gene
Postgerminal Center B-Lymphocyte of Unknown Differentiation Stage
A chromosome band present on 5q
5q23
One of two salivary glands in the neck, located in the space bound by the two bellies of the digastric muscle and the angle of the mandible. It discharges through the submandibular duct. (MeSH)
Submandibular Gland
Submaxillary Gland
GLAND, SALIVARY, SUBMANDIBULAR
Gland, Salivary, Mandibular
Tooth 1
The upper right 3rd molar, as defined by the Universal tooth numbering system.
Ulna
Ulna Bone
BONE, ULNA
One of the bones that comprise the forearm. The largest aspect articulates with the humerus at the elbow joint and the smallest portion of the ulna articulates with the carpal bones in the wrist.
6: 74287475-74283962
Physical location of EEF1A1_Gene
12: 15833589-15664365
Physical location of EPS8_Gene
18p11.3
A chromosome band present on 18p
A lymph node located along the internal iliac artery.
Internal Iliac Lymph Node
Toe Nail
A thin, horny translucent plate covering the end of each toe.
Toenail
9: 33254737-33245026
Physical location of BAG1_Gene
Retinoic Acid Response Element
A cis-acting transcription regulatory element. It is bound by the retinoic acid receptors.
RARE
Tissue composed of specialized cells that are organized as a definite organ, situated along the course of lymphatic vessels, and consisting of an outer cortical and an inner medullary part. The lymph nodes are the main source of lymphocytes of the peripheral blood and serve as a defense mechanism by removing noxious agents, such as bacteria and toxins, and probably play a role in antibody production.
LYMPH NODE
Lymph Gland
Lymph Node Tissue
Middle Frontal Convolution
Middle Frontal Gyrus
Right Common Carotid Artery
Neurenteric Canal
Palatal Muscle
A chromosome band present on 3q
3q22
White Commissure
Fetal Skull
A chromosome band present on 8q
8q11-q12
Any of the external or internal veins that drain the cerebral hemispheres.
Cerebral Vein
Right Lymphatic Trunk
The GSK-Binding Domain of AXIN2 mediates interaction with GSK3-Beta. Involved in regulation of the WNT signaling pathway, AXIN2 organizes an APC/Beta-Catenin/GSK3-Beta/ AXIN2 complex that leads to Beta-Catenin degradation. (NCI)
GSK-Binding Domain
1p33-p32
A chromosome band present on 1p
KIDNEY, HILUM
Hilar Area of Kidney
Hilum of the Kidney
Hilum of Kidney
Hilar Area of the Kidney
The concave area of the kidney through which the renal artery enters and the renal vein and ureter exit the organ.
HEART, APEX
The lowest superficial part of the heart which is situated behind the left 5th intercostal space.
Apex of the Heart
Intermediate Trophoblast
A trophoblast that travels into the junctional zone of the decidua, reacting with maternal tissue leukocytes, mainly NK cells, macrophages and T cells, and invades maternal blood vessels feeding the placenta, softening the walls and replacing the lining with fetal tissue. This junctional zone extends at the edge of the placenta to the amino-chorionic membranes where the chorionic laeve trophoblast has intimate contact with decidua tissue. One of the primary functions of this cell is in implantation and in the establishment of the uteroplacental circulation since it extensively invades the spiral arteries at the placental site.
Intermediate Type Trophoblastic Cell
Anal Region
The area that includes the anus and the perianal skin.
eccrine gland
An unbranched, coiled, tubular gland not associated with the hair follicle that promotes cooling by evaporation of its secretion. It is innervated by cholinergic nerve fibers.
Eccrine Sweat Gland
3q23
A chromosome band present on 3q
The external portion of any anatomic structure.
Anatomic Surface
19: 56946962-56940839
Physical location of FPR1_Gene
Ductus Santorini
Ductus Pancreaticus Accessorius
Anterior Tibial Artery Branch
An arterial branch arising from the anterior tibial artery.
Reproductive Body System
Reproductive Organ System
Reproductive System
The organs and tissues involved in the production and maturation of gametes and in their union and subsequent development as offspring.
The tissue layers that form the urinary bladder. They include the mucosa, submucosa, smooth muscle, and serosa.
Bladder Wall
A chromosome band present on 1p
1p35-p31.3
Physical location of ADRB1_Gene
10: 115793796-115795518
16q23.1
A chromosome band present on 16q
5q35
A chromosome band present on 5q
Oropharyngeal Lymphoid Tissue
Physical location of GUCY1A2_Gene
11: 106394381-106063120
Plantar Fascia
2: 136709450-136705639
Physical location of CXCR4_Gene
Rectosigmoid Region
Rectum and Sigmoid Colon
An area of the body consisting of the rectum and the sigmoid colon.
19q13.3
A chromosome band present on 19q
A graft transferred from one location to another within the same individual.
Autograft
Appendiceal Tip
Tip of the Appendix
Appendix Tip
The distal end of the appendix.
Right Spermatic Vein
Right Testicular Vein
Right Internal Spermatic Vein
A chromosome band present on 4q
4q34.1-q35.1
Killer Cell
Killer Cells, Natural
NK Cell
NK Cells
K lymphocyte
NK-Cell
Cytotoxic cell
Natural killer cells are cells that resemble large granular lymphocytes. They do not express markers of either T or B cell lineage. They are positive for CD16, CD56, and CD 94. These cells do possess Fc receptors for IgG and can kill target cells using antibody-dependent cell-mediated cytotoxicity. They can also use perforin to kill cells in the absence of antibody and killing may occur without previous sensitization.
K Cells
NK-LGL
Killer Cells
NK
Natural Killer Cell
Optic Nerve Head
Optic Papilla
Optic Disk
Second Cranial Nerve
Optic Disc
A portion of the retina at which the axons of the ganglion cells exit the eyeball to form the optic nerve. No light-sensitive photoreceptors are contained within this portion of the retina.
Evolutionary related to desmosomal desmogleins, cadherins contain a signal sequence, a propeptide of around 130 residues, an extracellular domain of around 600 residues, a single transmembrane domain, and a well-conserved C-terminal cytoplasmic domain of about 150 residues. The extracellular domain typically consists of four Cadherin Domain repeats of about 110 residues; an adjacent fifth domain contains four conserved cysteines. The domain includes conserved Asp and Arg residues that may be involved in calcium binding. Tissue-specific cadherin glycoproteins are responsible for homophilic calcium-dependent cell-cell adhesion likely involved in cell type sorting during morphogenesis, histogenesis, and regeneration. They may also regulate tight and gap junctions. (NCI)
Cadherin Domain
Ascending Limb of Henle's Loop
The ascending limb of the U-shaped portion of the renal tubule.
7: 72942807-72981505
Physical location of LIMK1_Gene
Cardiac Valve Cusp
Hyoid Muscle
Pyramid
A chromosome band present on 19q
19q13.2
A chromosome band present on 20q
20q13.13
Submandibular Duct
Wharton's Duct
5q34
A chromosome band present on 5q
Peyer's Patch Lymphoid Follicle
Peyer Patch Lymphoid Follicle
The parietal pleura that lines the mediastinum.
Mediastinal Pleura
Physical location of ACVR1_Gene
2: 158500579-158418469
7q31.1-q31.3
A chromosome band present on 7q
parietal peritoneum
Parietal Part of the Peritoneum
19q13.1
A chromosome band present on 19q
The amino acid residing in the first position of a protein or peptide.
Amino-Terminal Amino Acid
N-Terminal Amino Acid
Pseudoautosomal Region
The human Y chromosome is composed of two different parts: a pseudoautosomal region that is homologous to a region of the X chromosome and which is responsible for sex chromosome pairing and a Y-specific part that encodes the sex determining gene. Genes within the pseudoautosomal region are not sex linked.
A cell developed in the thymus that differentiates into a mature T-lymphocyte. The maturation is dependent on several transcription factors including GATA-3 and c-Myb. The expression of the pre-T cell receptor alpha (pTa) gene occurs exclusively in the immature T lymphocyte.
Immature T-Lymphocyte
Lumbar Plexus
A chromosome band present on 17p
17p13-p12
8: 6408172-6347601
Physical location of ANGPT2_Gene
A chromosome band present on 2q
2q21-q22
Left Lung Alveolar Duct
Diencephalon
Wharton's Jelly
Mucous Connective Tissue
A gelatinous type of connective tissue that is found in the umbilical cord.
Celiac Ganglion
That portion of the pancreas lying in the concavity of the duodenum.
Pancreas Head
Head of Pancreas
PANCREAS, HEAD
Pancreatic Head
Head of the Pancreas
Hematopoietic and Lymphatic System Part
Unipolar Neuron
A conducting cell of the nervous system that has only one process extending from the cell body. It is always a sensory neuron.
High Mobility Group Domain
HMG Box
Each HMG subfamily is a distinct set of proteins with identifiable structural characteristics and a specific type of targets to induce characteristic changes in the structure of its binding site.
HMG Domain
Esophageal Squamous Epithelium
Semispinalis Capitis
Buccal Artery
Germinative Follicular Epithelium
Tracheoesophageal Septum
Regional Lymph Node
LYMPH NODE, REGIONAL
A lymph node that drains lymph from a region of interest.
Supratentorial Brain
Supratentorial Nervous System
Supratentorial Anatomy
Physical location of GUCY1B3_Gene
4: 157037820-157085661
Germinal Epithelium
Hemispheric Cistern
Dentin
The hard portion of the tooth surrounding the pulp, covered by enamel on the crown and cementum on the root. Dentin is harder and denser than bone but softer than enamel.
Phlegm
2: 111597541-111640818
Physical location of BCL2L11_Gene
Endocrine Pancreas
The pancreatic tissue that contains the islets of Langerhans. It is responsible for the production and secretions of the pancreatic hormones.
PANCREAS, ENDOCRINE
Satellite DNA
DNA that contains many tandem highly repetitive sequences, that have a base composition (and thus density) sufficiently different from that of normal DNA that it sediments as a distinct band in cesium chloride density gradients. Satellite DNA is located at very specific spots in the genome (on chromosomes 1, 9, 16 and the Y chromosome, the tiny short arms of chromosomes 13-15 and 21 and 22, and near the centromeres of chromosomes).
Iliacus
Inferior Maxillary Nerve
Thyro-epiglottic Muscle
Thyroepiglottic Muscle
Nitrergic Neuron
Nitrergic Neurons
Nitroxidergic Neurons
A nerve cell that uses nitric oxide as its neurotransmitter.
Pulmonary surfactant lines the lung epithelium and lowers surface tension to prevent collapse at end-expiration. Deficiency of pulmonary surfactant results in respiratory distress syndrome (RDS) in premature infants. Lung surfactant is synthesized in alveolar type II cells, stored in lamellar bodies and secreted via exocytosis.
Surfactant, Lung
Surfactant
Lung Surfactant
Perimetrium
The serosal surface of the uterus.
Uterine Body Serosal Surface
Pars Externa
13: 42464366-42360123
Physical location of EPSTI1_Gene
Pancreatic Endocrine Secretion
Endocrine Pancreas Secretion
Herring Body
Pia Mater
The delicate, highly vascular, innermost membrane encasing the brain and spinal cord.
A chromosome band present on 12p
12p12.1
14: 89933126-89944151
Physical location of CALM1_Gene
A salivary gland located under the tongue in the floor of the oral cavity.
GLAND, SALIVARY, SUBLINGUAL
Sublingual Gland
Sublingual Salivary Gland
Thyroid Gland Lobe
A chromosome band present on 7q.
7q32.2
Skin Graft
Superficial Abdominal Muscle
Physical location of CASP4_Gene
11: 104344503-104318805
Physical location of FNTA_Gene
8: 43030641-43060080
Duct
A tube that carries various secretions from one part of the body to another.
8q11.2
A chromosome band present on 8q
4: 81545011-81569338
Physical location of FGF5_Gene
A chromosome band present on 7q
7q32.3
Intraepithelial T-Lymphocyte
A mature T lymphocyte that migrates into epithelial tissue and contributes to the local and the systemic immune response.
Enteric Ganglion
Internal Malleolar Artery
A chromosome band present on 5q
5q13-q14
Pericardioperitoneal Canal
Hypaxial Division of the Myotome
Hypaxial Division of Myotome
Beta Pleated Sheet
In a b-sheet two or more polypeptide chains run alongside each other and are linked in a regular manner by hydrogen bonds between the main chain C=O and N-H groups. The R-groups (side chains) of neighbouring residues in a b-strand point in opposite directions; beta sheets can be parallel, anti-parallel or mixed. (from expasy.org)
Beta Sheet
Paracolic Gutter
Either of the two naturally ocurring spaces between the colon and the abdominal wall, lateral to the ascending and descending colons.
Catheter Site
SITE, CATHETER
The anatomic site through which fluid is transferred into or out of the body using a catheter.
Trochlear Nerve
The cranial nerve that controls the superior oblique muscle of the eye.
Fourth Cranial Nerve
Cranial Nerve IV
GXGXXXG Motif
The GXGXXXG Motif is often found it the NAD-binding domain (often N-terminal) in metabolic enzymes involved in glycolysis, glyconeogenesis, and the citric acid cycle, such as GAPDH (glyceraldehyde-3-phosphate oxidation and phosphorylation), lactate dehydrogenases (lactate to pyruvate conversion), and malate dehydrogenases (malate to oxaloacetate interconversion). (NCI)
Physical location of KLRB1_Gene
12: 9651758-9639137
3q13.1-q13.2
A chromosome band present on 3q
Dorsal Cochlear Nucleus
A chromosome band present on 14q
14q24.1
A form of articulation in which the bones are connected by intervening substance admitting slight motion.
Amphiarthrosis
Symphysis
Mammary Gland Fat Pad
Mammary Gland Fat-pad
A mass of adipose tissue in the breast that is surrounded by fibrous tissue.
Breast Fat Pad
A chromosome band present on 10q
10q25
Hemorrhoidal
LARGE INTESTINE, RECTUM
Rectum
The terminal portion of the gastrointestinal tract, extending from the rectosigmoid junction to the anal canal.
NLS
Nuclear Localization Signal
An amino acid sequence that directs the post-translational transport of a protein to the nucleus. The sequence contains positively charged amino acids such as arginine and lysine.
2p23.3-p23.2
A chromosome band present on 2p
Seminiferous Cord
One of the subdivisions of the lung, 2 in the left lung and 3 in the right lung.
Lung Lobe
Lateral Geniculate Body
The lateral of a pair of small oval masses that protrude slightly from the posteroinferior aspect of the thalamus; commonly considered a part of the metathalamus.
External Geniculate Body
Ileo-Colic Artery
The third of the seven cervical vertebrae.
C3 Vertebra
Right Subclavian Artery
Superior Constrictor Muscle
A portion of an organ, such as the liver, lung, breast, or brain.
Lobe
Physical location of EPHA3_Gene
3: 89239364-89613974
10q26
A chromosome band present on 10q
Virchow Cell
Virchow's Cell
Seminiferous Epithelium
9: 97825196-97857776
Physical location of ANP32B_Gene
Fluids and secretions related to the nervous system. The entire nerve apparatus, composed of a central part, the brain and spinal cord, and a peripheral part, the cranial and spinal nerves, autonomic ganglia, and plexuses.
Nervous System Fluids and Secretions
Nervous System, Fluids, Secretions
Nervous System-Fluids, Secretions
Nervous System Fluids, Secretion
Free Edge of the Nail
11: 88420838-87881006
Physical location of GRM5_Gene
6q23-q24
A chromosome band present on 6q
Epithelial cell lining of a crypt.
Crypt Epithelium
4q28.2-q31.1
A chromosome band present on 4q
Supraglottis
The upper part of the larynx, including the epiglottis; the area above the vocal cords.
Xq26.3-q27.1
A chromosome band present on Xq
2: 133008348-133236911
Physical location of GPR39_Gene
Small Intestinal Mucosa
Mucosa arranged into two fundamental structures - villi and crypts of Lieberkuhn. Villi are projections into the lumen of the small intestine, covered with simple columnar epithelium. Crypts of Lieberkuhn are moat-like invaginations of the epithelium around the villi that extend through the lamina propria down to the muscularis mucosae. Lymphocytes often invade the epithelium or form solitary lymphoid nodules in the lamina propria. Lymph nodules may form longitudinal aggregations of 30-50 nodules in the lamina propria of the ileum. These large aggregations are called Peyer's patches. The muscularis mucosae has two layers and extends into the intestinal villi, where the smooth muscle cells form a longitudinal bundle in the centre of the villi. The small intestinal mucosa secretes gastrin, somatostatin, cholecystokinin and secretin.
Cells in invertebrates which are specialized to detect and transduce light and darkness and relay that information centrally in the nervous system. (MeSH)
Photoreceptors, Invertebrate
Peripheral Nerve
Any nerve outside the brain or spinal cord that connects with peripheral receptors or effectors.
NERVE, PERIPHERAL
Peripheral Nerves
The twelfth thoracic vertebra counting from the top down.
T12 Vertebra
Respiratory System
Pulmonary Body System
Pulmonary Organ System
Respiratory system (all sites)
Organ System, Pulmonary
Body System, Pulmonary
respiratory tract
5: 172130809-172127707
Physical location of DUSP1_Gene
Omohyoid
Members of the polo subfamily of protein kinases appear to play pivotal roles in cell division and proliferation. These include mammalian Plk, Snk, and Fnk/Prk, Xenopus laevis Plx1, Drosophila melanogaster polo, Schizosaccharomyces pombe Plo1, and Saccharomyces cerevisiae Cdc5. The polo family members are characterized by the presence of a distinct region of homology in the C-terminal non-catalytic domain, termed the polo-box, which is essential for subcellular localization and mitotic functions of the polo kinases. Regulation of polo kinases may be crucial in the control of cell division.
Polo-Box Domain
A chromosome band present on 22q
22q13.2
1: 68228334-68223668
Physical location of ARHI_Gene
Cricothyroid Muscle
Anastomotica Magna Artery
A brachial artery branch with distribution to the muscles at the back of the elbow.
Physical location of CDC45L_Gene
22: 17841970-17882689
An organ present in some vertebrates during embryonic gestation that surrounds the fetus and provides it with nutrients and oxygen, facilitates gas and waste exchange between the fetus and mother, and provides parasitic cloaking from the mother's immune system by excretion of neurokinin B.
Placenta
Placental
Hydroxy
Hydroxyl
Hydroxyl Group
The monovalent group -OH in such compounds as bases and some acids and alcohols.
Lateral Wall of Oropharynx
Lateral Wall of the Oropharynx
1p22-p21
A chromosome band present on 1p
Innominate Artery Branch
Adenohypophysial Cell
One of five types of secreting cells (somatotrophs, lactotrophs, corticotrophs, thyrotrophs, and gonadotrophs) found in the anterior lobe of the pituitary gland.
The tissue of the liver. It includes the hepatic lobules, hepatic sinusoids, perisinusoidal spaces, and portal triad. The hepatic lobules are composed of hepatocytes.
Hepatic Tissue
Liver Tissue
Hepatic Parenchyma
LIVER
SMALL INTESTINE, JEJUNUM
The portion of the small intestine that extends from the duodenum to the ileum.
Jejunum
13: 50538143-50466770
Physical location of GUCY1B2_Gene
A chromosome band present on 22q
22q13.1
The lowest central region of the abdomen, below the umbilical region and between the two iliac regions.
Hypogastric Region
Pubic Region
Hypogastric
Suprapubic Region
Hypogastrium
Pubic Area
Any of the lymph nodes adjacent to the stomach and duodenum.
LYMPH NODE, HEPATIC
Hepatic Lymph Node
A simple cuboidal epithelial cell lining the collecting duct of the kidney. Its function is dependent upon its location on the collecting duct.
Collecting Cell
Spongy discs located between the vertebrae of the spinal column; composed of the outer annulus fibrosus and inner nucleus pulposus.
Intervertebral Disc
Surface Ectoderm
11q13-q14
A chromosome band present on 11q
Tract of Burdach
An epithelial cell that exists in the early fetal thymus that has the capacity to give rise to both cortical and medullary thymic epithelium.
Thymic Epithelial Stem Cell
Physical location of CXCL9_Gene
4: 77285820-77279802
Protein Binding Domains are structural motifs responsible for the peptide/protein binding activity of proteins.
Protein Binding Domain
Protein Binding Motif
Protein-Protein Interaction Domain
Respiratory System Fluid or Secretion
Fluids and secretions relating to the respiratory system.
Respiratory System Fluid and Secretion
Respiratory System Fluids and Secretions
Respiratory System-Fluids, Secretions
The lower part of the epididymis.
Tail of the Epididymis
CAUDA EPIDIDYMIS
Physical location of COL4A3_Gene
2: 227854786-228005012
Corpus Callosum
A white matter structure within the cleft that separates the left and right cerebral hemispheres in the mammalian brain. It is composed of a wide, flat bundle of 200-250 million axonal projections.
A chromosome band present on 10p
10p12.3-p11.2
Jaw
The bones of the skull that frame the mouth and serve to open it; the bones that hold the teeth.
Primary Palate
Orbitalis Muscle
14q11.1-q11.2
A chromosome band present on 14q
Ampullary Crest
Cristae Ampullaris
A sensory receptor of the ear located in the membranous ampulla of the semicircular duct.
1p32.3-p31.3
A chromosome band present on 1p
3: 50624207-50618930
Physical location of CISH_Gene
13q12-q13
A chromosome band present on 13q
Body of Vertebra
Body of the Vertebra
Vertebral Body
The cardiovascular and lymphatic systems, collectively.
Vascular System
The part of the epidermis layer of the skin containing Langerhans cells, which are dendritic, MHC class II-expressing antigen presenting cells.
Spiny Layer
Stratum Spinosum
Middle Constrictor Muscle
10q21
A chromosome band present on 10q
Bulbourethral Gland Secretion
Superior Wall of the Nasopharynx
Superior Wall of Nasopharynx
Mantle Zone
Posterior Foramen Magnum
The fourth thoracic vertebra counting from the top down.
T4 Vertebra
4q12-q21
A chromosome band present on 4q
The space in which the vocal cords are located.
Glottis
Middle Third of Esophagus
ESOPHAGUS, MIDDLE THIRD
The middle one third of the esophagus in which the muscle layer is composed of muscle cells of the striated and smooth types.
Middle Third of the Esophagus
Sacral
S Spine
Sacral Spine
Sacrum
The triangular bone, made up of 5 fused bones of the spine, located in the lower area of the spine between the fifth lumbar vertebra and the coccyx.
Primordial Follicle
A chromosome band present on 14q
14q24.3
Physical location of GNB1_Gene
1: 1854657-1748892
Leydig Cell
Cells in the interstitial tissue of the testis that are believed to furnish the internal secretion of that gland. (MeSH)
Interstitial Cell of Leydig
Leydig Cells
Interstitial Cell
Interstitial Cell of the Testis
Interstitial Cell of Testis
Arcuate Nucleus
A nucleus located in the middle hypothalamus in the most ventral part of the third ventricle near the entrance of the infundibular recess. Its small cells are in close contact with the ependyma.
10q22
A chromosome band present on 10q
10q24
A chromosome band present on 10q
Detrusor Muscle of the Bladder
Muscularis Propria
The detrusor muscle of the bladder, forming the muscular wall of the bladder, consisting of the inner longitudinal; middle circular; and outer longitudinal layers.
Round Ligament of the Liver
Intron
Non-coding, intervening sequences of DNA that are transcribed, but are removed from within the primary gene transcript and rapidly degraded during maturation of messenger RNA.
Intervening Sequence
Intronic
5: 42601723-42757736
Physical location of GHR_Gene
CA2 Field of the Cornu Ammonis
Connective Tissue
The supporting or framework tissue of the animal body, formed of fibrous and ground substance with more or less numerous cells of various kinds; it is derived from the mesenchyme, and this in turn from the mesoderm; the varieties of connective tissue are: areolar or loose; adipose; dense, regular or irregular, white fibrous; elastic; mucous; and lymphoid tissue; cartilage; and bone; the blood and lymph may be regarded as connective tissues the ground substance of which is a liquid.
A chromosome band present on 11p
11p15
A valve that is located between and controls the flow of blood from the right ventricle of the heart and the pulmonary artery.
Pulmonary Valve
VALVE, PULMONARY
Pulmonic Valve
A spindle-shaped cell that exhibits characteristics of both fibroblasts and smooth muscle cells. It has an elongated nucleus and does not have basal lamina. The cytoplasm can be distinguished from the surrounding matrix because of actin filaments, myosin and other muscle proteins arranged to suggest a contractile ability.
Myofibroblast
Neck
The region that connects the head to the rest of the body.
Cervical
Frizzled Cystein-Rich Domain
Frizzled CRD
Fz Domain
A 120 amino acid protein domain, with an alpha-helical structure, containing 10 cysteines, which have conserved spacing throughout the sequence. This domain is involved in the recognition of extracellular ligands.
Frizzled Domain
Vein of the Head or Neck
Ovarian Follicle Fluid
Abducens Nerve
Sixth Cranial Nerve
Cranial Nerve VI
Nervus Abducens
A cranial nerve that supplies motor impulses to the lateral rectus muscle of the eye.
A chromosome band present on 11p
11p13
Physical location of CYP2E1_Gene
10: 135229746-135241501
Neurovascular Bundle
A body structure consisting of nerves traveling together with arteries, veins, and/or lymphatics.
Ridge of the Aqueductus Fallopii
The ninth thoracic vertebra counting from the top down.
T9 Vertebra
Left Anterolateral Segment
Couinaud Segment III
Couinaud segment III, corresponding to the lateral segment of the left lobe of the liver, located to the left of the inferior portion of the falciform ligament, anteriorly overlapping the stomach.
Trigonum Olfactorium
17q11.2
A chromosome band present on 17q
Lumbar Spinal Nerve Roots
Lumbar Spinal Nerve Root
Stellate Reticulum
Horny Layer
Stratum Corneum
Physical location of AVPR2_Gene
X: 152691217-152693487
Mast cells are hematopoietic tissue cells that contain coarse, basophilic, metachromatic granules. They are believed to contain heparin and histamine and derive from hematopoietic progenitor cells.
Mast Cells
Mastocyte
Marrow Mast Cell
Basophils, Tissue
Basophilic Histiocyte
Mast Cell
The medial bone of the proximal row of carpal bones.
Pisiform Bone of Hand
Pisiform
Pisiform Bone
A chromosome band present on 11p
11p12
A chromosome band present on 7p
7p15.2
Visceral Epithelial Cell
Podocyte
A modified epithelial cell of the capsular epithelium of the renal glomerulus. It has a small perikaryon and a number of primary and secondary foot-like radiating processes (pedicels) that interdigitate with those of other podocytes and embrace the basal lamina of glomerular capillaries.
Trapezius Muscle
One of a pair of flat, large, triangular muscles that extend from the external occipital protuberance and the medial third of the superior nuchal line of the occipital bone to the middle of the back. The trapezius muscle is involved in moving the shoulder and arm.
Any cylindrical, vertical, upright structure.
Column
The middle segment of the anal canal between the colorectal and squamous zones.
Anal Transitional Zone
Macula Densa
Physical location of DCK_Gene
4: 72224427-72261648
Dendritic Cells, Follicular
Follicular Dendritic Cells
Follicular Dendritic Cell
Antigen Presenting Cells (APCs) located in the follicles of secondary lymphoid organs. These dendritic cells are unique because of their location, primarily in lymphoid follicles, and because of their function in retaining antigen molecules for extended periods of time and serving as APCs for B cells.
12: 68039799-68070843
Physical location of GAS41_Gene
Spermatogenic Cell
A cell that produces sperm.
The parenchyma of the spleen, consisting of lymphocytes and macrophages. It lies between the splenic trabecula. Red pulp is the part suffused with blood and white pulp consists of areas of lymphatic tissue where there are sleeves of lymphocytes and macrophages.
Splenic Pulp
A chromosome band present on 7p
7p15.1
A chromosome band present on 16q
16q24.1-q24.2
Physical location of DHFR_Gene
5: 79986572-79957804
11: 125438397-125335784
Physical location of CDON_Gene
5: 126140732-126200608
Physical location of LMNB1_Gene
The lateral prominence of the pelvis from the waist to the thigh.
Hip
Eyelid
A thin membrane of skin with the purpose of covering and protecting an eye.
Palpebra
Nucleosome
The repeating structural units of chromatin, each consisting of approximately 200 base pairs of DNA wound around a protein core. This core is composed of the histones H2A, H2B, H3, and H4.
A cell located in the collecting tube of the nephron..
Light Cell
Myeloblast
myeloblastic
An immature cell that represents the first stage in the granulocytic series of hematopoiesis. It is found in bone marrow and differentiates into a promyelocyte. Its nucleus is composed of very fine, evenly distributed chromatin with 2-5 nucleoli. The cytoplasm is basophilic and non-granular.
HEENT
Head, Ears, Eyes, Nose and Throat
HEENT is the Head, Ears, Eyes, Nose and Throat, and is referred to as a body system on a physical or medical examination. The term is typically used as 'HEENT' in a physician or caregiver notes.
A unicellular mucous cell found in the epithelium of the small intestine. Droplets of mucigen collect in the upper part of the cell and distend it, while the basal end remains slender, and the cell assumes the shape of a goblet.
Small Intestinal Goblet Cell
Nerve
Part of the peripheral nervous system composed of bundles of nerve fibers running to various organs and tissues of the body using chemical and electrical signals to transmit sensory and motor information from one body part to another.
Nervous
2: 215499872-215418783
Physical location of BARD1_Gene
Retinal Fissure
Wolffian Duct
A duct in the embryo draining the mesonephric tubules.
Mesonephric Duct
The synovial juncture between the medial end of the clavicle and the anterior segment of the sternum.
Sternoclavicular Joint
12q12-q14
A chromosome band present on 12q
Episclera
Episcleral Layer
A thin fibrous membrane that covers the outer surface of the anteriors sclera and contains blood vessels which supply the sclera.
11: 101723176-101754611
Physical location of BIRC2_Gene
Splenic Vein
1p36.2-p36.1
A chromosome band present on 1p
Physical location of AGR2_Gene
7: 16617848-16604676
Superior Frontal Convolution
Superior Frontal Gyrus
Memory B Cell
Memory B-Lymphocyte
Deep Temporal Vein
Ankle Skin
The skin that surrounds the tissues of the ankle joint.
Anatomic Sites, Other
A chromosome band present on 20q
20q12-q13.11
Falciform Ligament
Esophageal Glandular Cell
An epithelial cell that covers the lower third of the esophageal lumen. It is also found in the submucosal glands of the esophagus.
The bodily fluid that fills the space between the bony labyrinth and the membranous labyrinth of the inner ear.
Perilymph
16q24.3
A chromosome band present on 16q
Th1 Cells
Th1 Cell
Th-1 Cell
Type 1 Helper Cells are a subset of helper-inducer T-lymphocytes which synthesize and secrete interleukin-2, gamma-interferon, and interleukin-12. Due to their ability to kill antigen-presenting cells and their lymphokine-mediated effector activity, these cells are associated with delayed-type hypersensitivity reactions.
Type 1 Helper Cell
Viscera
10: 128658955-129140571
Physical location of DOCK1_Gene
20q12-q13.12
A chromosome band present on 20q
Deep Intracranial Venous System
A chromosome band present on 6q
6q26-q27
17q11.1
A chromosome band present on 17q
Corniculate Cartilage
Cardiovascular system (all sites)
Vascular, Heart
Cardiovascular Body System
Cardiovascular
Organ System, Cardiovascular
Cardiovascular System
Cardiovascular Organ System
Body System, Cardiovascular
circulatory system
Relating to the heart and the blood vessels or the circulation.
Tubotympanic Recess
The joint between the head of the lower mandible and the temporal bone.
Temporomandibular Joint
TMJ
Jaw Joint
Upper Gastrointestinal Tract
GASTROINTESTINAL TRACT, UPPER
The upper part of the gastrointestinal tract that includes the esophagus, stomach, and duodenum.
Xp11.3-p11.23
A chromosome band present on Xp
Internal Carotid Artery Branch
A chromosome band present on 12q
12q12-q13
Physical location of CDC25A_Gene
3: 48204805-48173672
Inferior Vena Cava Opening
15: 72861768-72882558
Physical location of CSK_Gene
Dimeric Tubulin Molecule
A protein complex containing one alpha tubulin and one beta tubulin.
Lower Hypopharyngeal Region
Neurofilament
An intermediate filament that is found in the axons of neurons.
Zygomaticus Major
Histiocytes
Fixed Macrophage
Histiocyte
A macrophage present in connective tissue.
Esophageal Gland
Diarthrosis
Synovial Joint
A form of articulation admitting considerable motion.
4q13.1
A chromosome band present on 4q
Endocrine Cell
Ectocervical Mucosa
The mucous covering of the vaginal portion of the cervix. It is composed of epithelium, basement membrane, lamina propria mucosae, and lamina muscularis mucosae.
6p21-p12
A chromosome band present on 6p
Connections between cells which allow passage of small molecules and electric current. Gap junctions were first described anatomically as regions of close apposition between cells with a narrow (1-2 nm) gap between cell membranes. The variety in the properties of gap junctions is reflected in the number of connexins, the family of proteins which form the junctions.
Nexus
Nexus Junction
Communicating Junction
Low-resistance Junction
Gap Junction
Basophilic Erythroblast
A nucleated red blood cell that stains readily with basic dye.
Other Body Part
A thick, protein-rich substance secreted by the breasts during the second half of pregnancy and for a few days after birth before the breast milk comes in. It contains antibodies which serve to give the baby protection from disease and also has a laxative effect on the colon which helps to expel the plug of meconium and facilitate the establishment of normal bowel movements.
Colostrum
Medial Vestibular Nucleus
12: 97541546-97631679
Physical location of APAF1_Gene
Female Reproductive System Part
Tissue characterized by a thick, random arrangement of collagen and elastin fibers with very few cells. The majority of the cells are fibroblasts, but mast cells and macrophages may also be seen. It is found in the dermis, periosteum, perichondrium, capsules of organs and sheaths of nerves and muscles.
Irregular Dense Connective Tissue
Epithalamus
The dorsal posterior subdivision of the diencephalon. The epithalamus is generally considered to include the habenular nuclei and associated fiber bundles, the pineal body, and the epithelial roof of the third ventricle. (MeSH)
A chromosome band present on 12p
12p13-p12.3
Membranous Labyrinth
Cytosolic Domain
Cytoplasmic Tail
The part of a transmembrane protein which projects into the cytoplasm.
Cytoplasmic Domain
Ulnar Artery
A chromosome band present on 11p
11p15.3-p15.1
T1 Vertebra
The first thoracic vertebra counting from the top down.
17: 7063754-7033933
Physical location of DLG4_Gene
Nitabuch's Fibrinoid
A protein matrix located between the placenta and the myometrium.
15: 57736987-57718358
Physical location of GTF2A2_Gene
Physical location of AXL_Gene
19: 46416663-46459511
A chromosome band present on 12p
12p12.3
Terminal Bar
Physical location of ARHA_Gene
3: 49424403-49371582
Adhesive Junction
Adhering Junction
Anchoring Junction
Anchoring junctions typically are observed as "spot welds" between cells in many types of epithelia. Detail structures can be seen only with EM.
Left Innominate Vein
Neurons, Dorsal Horn
Neurons, Posterior Horn
Posterior Horn Cells
Dorsal Horn Cells
Posterior Horn Cell
Neurons in the posterior (dorsal) horn of the spinal cord whose cell bodies and processes are confined entirely to the central nervous system. They receive collateral or direct terminations of dorsal root fibers. They send their axons either directly to anterior horn cells or to the white matter ascending and descending longitudinal fibers.
Posterior Circumflex Artery
Cortical Nephron
Subcapsular Nephron
B9 ENDOCRINE PANCREAS
Islet Cells
Pancreatic Islets
Nesidioblasts
Islet of Langerhans
Islets of Langerhans
Islands of Langerhans
Pancreas, Endocrine
Pars endocrina pancreatis
Langerhans Islets
Corpus Spongiosum
Vallecula
The portion of myometrium adjacent to the endometrium.
Superficial Myometrium
Physical location of EPS8L1_Gene
19: 60275200-60291103
Right Lymphatic Duct
Inferior Hypogastric Nerve Plexus
LYMPH NODE, PORTAL
Portal Lymph Node
Lymph nodes surrounding the portal vein.
Pericardiacophrenic Vein
Physical location of G22P1_Gene
22: 40341854-40384543
Fundus Uteri
Sural Nerve
A peripheral nerve that runs close to the small saphenous vein. It supplies innervation to the skin of the lower back of the leg and sends a branch to the lateral side of the foot and little toe.
NERVE, SURAL
First Pharyngeal Arch
Xq22.3
A chromosome band present on Xq
A chromosome band present on 7q
7q31.1-q31.2
Chromosome 4 Physical Location
Venule
Limbs
Extremity
EXTREMITIES
A body region referring to an upper or lower extremity.
Limb
Pleuropericardial Membrane
Primary Chorionic Villus
A chromosome band present on 16p
16p11.2-p11.1
Xq22.2
A chromosome band present on Xq
Physical location of CSNK2A1_Gene
20: 472482-411340
Skin of the Lower Limb and Hip
Skin of Lower Limb and Hip
Epigastric Region
Epithelial Reticular Cell
A branched epithelial cell that supports epithelial structures.
Epithelial Reticular Cells
A chromosome band present on 17q
17q22-q23
VALVE, TRICUSPID
A dual-flap valve of the heart that regulates the flow of blood between the right atrium and the right ventricle of the heart.
Tricuspid Valve
Physical location of CD72_Gene
9: 35608408-35599976
C6 Zinc Cluster
The zinc cluster is one of three structural motifs observed in the DNA-binding domains of zinc proteins. In the "zinc cluster" two zinc atoms are liganded by six cysteine residues. Originally identified in the GAL4 transactivator, it is also known as the C6 zinc cluster, binuclear cluster, and the Zn(II)2Cys6 motif.
Zinc Cluster
Posterior Annular Ligament
Anatomic Structures and Systems
A human biological structure, fluid or other substance; excludes single molecular entities.
Anatomic Structure, System, or Substance
Anatomic Structure or System
Peripheral Nervous System Part
Aryepiglottic Muscle
A band of muscular fibers of the oblique arytenoid muscle that extends from the summit of the arytenoid cartilage to the side of the epiglottis and whose action constricts the laryngeal aperture.
Serum Albumin
Xq22.1
A chromosome band present on Xq
Liver Lobe
Ribosomes are small organelles composed of ribosomal RNA (rRNA) and 80 some different proteins. rRNA is synthesized in the nucleolus and the ribosomal subunits are assembled there from rRNA and imported cytoplasmic made proteins. Once assembled, the subunits pass through the nuclear pores to the cytoplasm where they take part in protein synthesis. Some ribosomes are free in the cytoplasm and can be recruited to a polyribosomal structure when a messenger RNA (mRNA) strand is to be translated into a cytoplasmic protein. Other ribosomes are attached to the endoplasmic reticulum where the protein is formed within the interior to the endoplasmic reticulum. These proteins are destined for secretion, storage or incorporation into membranes.
Ribosomal
Ribosome
Physical location of CD47_Gene
3: 109281882-109244836
5: 148186369-148188379
Physical location of ADRB2_Gene
The cysteine-rich N-terminal DAG/PE (Diacylglycerol/Phorbol Ester)-Binding (C1) Domain of PKC isoforms interacts with phorbol ester or with the phospholipid-derived second messenger diacylglycerol. C1 contains one or two copies of a Cys-rich domain about 50 amino-acid residues long; the domain binds two zinc ions, probably involving the conserved cysteines and histidines. Bound to DAG, C1 domains are involved in recruitment of proteins to the membrane via basic residues that interact with lipid head groups. Part of the domain contains two beta sheets that form a cavity and a short C-terminal alpha helix; another contains two zinc-binding sites that maintain the domain fold. Binding of diacylglycerol, or phorbol ester, to the domain results in modification of protein function. (NCI)
DAG/PE-Binding Domain
Phorbol Ester Binding Domain
Protein Kinase C Conserved Region 1 Domain
Diacylglycerol Binding Domain
DAG Binding Domain
C1 Domain
A chromosome band present on 19q
19q13.4
Phrenic Nerve
Either of a pair of nerves that arise in the cervical plexus and provide innervation of the diaphragm.
The smaller of the two types of spiral grooves found on a right-handed DNA double helix; located between the sugar phosphate backbones of two DNA strands.
Minor Groove
Middle Cuneiform Bone of the Foot
Corpora Cavernosa
G-Quadruplex
G-Quartets
G-quadruplexes are multi-stranded structures held together by square planes of four guanines ('G-quartets') interacting by forming Hoogsteen hydrogen bonds. G-quartet structures has been developed as novel anti-HIV agents. Several critical structure-activity relationships between HIV-1 integrase and G-quartet oligonucleotides have been demonstrated.
G-Quadruplexes DNA
G-Quartet Structures
G4-DNA
G-Tetrads
G-Quadruplexes
A cell derived from a myeloid progenitor cell. It differentiates into a promonocyte. It is about 12 to 20 micrometer in diameter, has a round to oval nucleus with fine, lightly dispersed chromatin and one to four nucleoli. The cytoplasm is agranular, stains moderately to lightly basophilic, and often has an intensely stained periphery and a prominent perinuclear zone. Monoblasts are found in bone marrow and never appear in the normal peripheral blood.
Monoblast
Physical location of BMX_Gene
X: 15278609-15334309
16: 88169677-88191155
Physical location of CPNE7_Gene
A chromosome band present on 5q
5q11.2
The anatomic site at which medical intervention is administered.
SITE, APPLICATION
Site, Exposure
Application Site
Embryonic Cardiovascular System
Cuboidal Epithelium
Prostate Gland Lobe
Third Cranial Nerve
Cranial Nerve III
Oculomotor Nerve
The anterior surface of the liver tissue. It consists of the right and left lobes.
Anterior Surface of the Liver
Spinal Nerve Roots
Spinal Roots
Spinal Nerve Root
Primitive Streak
Physical location of DEC1_Gene
9: 114983651-115244477
Glandular
Gland
Bladder Muscular Coat
3: 39296526-39279991
Physical location of CX3CR1_Gene
Bilaminar Embryonic Disc
An embryonic structure that appears as a disc composed of epiblast and hypoblast sac.
Lymph Node by Anatomic Site
Supratentorial Cistern
22: 39812290-39900045
Physical location of EP300_Gene
A chromosome band present on 10q
10q23.2-q23.33
A chromosome band present on 8p
8p21.1
Physical location of EXTL2_Gene
1: 101072389-101049965
Right Portion of the Diaphragm
Labyrinthine Artery
Internal Auditory Artery
Ventroposterior Lateral Nucleus of the Thalamus
11: 66790663-66810945
Physical location of ADRBK1_Gene
Female Genital System Fluid and Secretion
Female Genital System Fluid or Secretion
Popliteal Lymph Node
LYMPH NODE, POPLITEAL
Lymph node located within the fat layer of the knee joint.
Duct Salivary Gland System
The portion of the salivary system that conveys the saliva produced in the acinar salivary gland system to the oral cavity. The duct salivary gland system includes the ductus parotideus, ductus submandibularis, ductus sublingualis major, and ductus sublinguales minores, as well as the ducts from the minor salivary glands.
The part of the cell membrane that faces the exterior of the cell.
Cell Surface
Part of the chromosome bands present on the long (q) arm of chromosome 1.
1q25.2
Circumflex Branch of the Left Coronary Artery
Circumflex Branch of Left Coronary Artery
Posterior Temporal Artery
Lesser Curvature of the Stomach
Lesser Curvature of Stomach, NOS
Ejaculatory Duct
Posterior Median Fissure of the Spinal Cord
The layer investing the lungs and dipping into the fissures between the several lobes.
Visceral Pleura
Physical location of GHRH_Gene
20: 35318706-35312903
Gastric Mucosa
Optic Chiasm
optic chiasma
An anatomic structure formed by the crossing of the two optic nerves under the hypothalamus.
A chromosome band present on 8p.
8p21.3
Physical location of BMP10_Gene
2: 69010300-69004264
Peripheral (Post-Thymic) T-Lymphocyte
Interlobular Duct
Chiasmatic Cistern
Third Portion of Duodenum
Transverse Portion of the Duodenum
Transverse Portion of Duodenum
Third Portion of the Duodenum
Other Embryologic Structure
Physical location of CHGB_Gene
20: 5840168-5854003
18: 44731079-44700221
Physical location of MADH7_Gene
Physical location of GNB2_Gene
7: 99916026-99921443
Anterior Commissure
A rounded band or bundle of nerve fibers that connects the two hemispheres of the brain.
GANGLION, DORSAL ROOT
Dorsal Root
Dorsal Root Ganglion
Ganglion with sensory function within the vertebral column.
Inferior Turbinate
Pulmonary Acinus
Ligand Binding Domain
Binding Site
Binding Site Domain
A Binding Site Domain is a region of protein that physically interacts stereospecifically, and usually at high affinity, with a specific ligand, substrate, or a specific domain of some complex target biomolecule, such as a protein, lipid, carbohydrate, or nucleic acid. Typically, but not necessarily, the interaction results in protein conformational alteration and functional modification.
A chromosome band present on 8p
8p21.2
Bone Marrow, Femur
Bone Marrow, Femoral
Bone marrow in the femoral bone.
DsRBD Domain
Double-Stranded RNA-Binding Domain
dsRBD
Double-Stranded RNA Binding Domain
The Double-Stranded RNA Binding Domain is found in a variety of RNA-binding proteins with different structures and exhibiting a diversity of functions. It is involved in localization of at least five different mRNAs in the early Drosophila embryo and by interferon-induced protein kinase in humans, which is part of the cellular response to dsRNA. (InterPro IPR001159)
A tube-like invagination of the epidermis from which the hair shaft develops and into which the sebaceous glands open; the follicle is lined by a cellular inner and outer root sheath of epidermal origin and is invested with a fibrous sheath derived from the dermis.
Hair Follicle
Hair Follicles
Follicles
Axodendritic Synapse
A synapse between the axon of one neuron and the dendrite of another neuron.
A fibrogranular network of residual structural elements within which are immersed both chromatin and ribonucleoproteins. It appears to extend throughout the nuclear interior from the nucleolus to the nuclear pore complexes along the nuclear periphery.
Nuclear Matrix
Radial Artery
The branch of the brachial artery that passes down the forearm.
Blood Vessel Endothelium
Nasal Muscle
Nasalis Muscle
Hepatic Duct
Arachnoid Membrane
A delicate fibrous membrane interposed between the dura mater and the pia mater of the brain and spinal cord. It is separated from the pia mater by the subarachnoid space.
Physical location of EDN1_Gene
6: 12398645-12404771
7p12.1
A chromosome band present on 7p
19: 18719800-17797961
Physical location of JAK3_Gene
Physical location of BCL10_Gene
1: 85455604-85443954
Transverse Facial Artery
Ascending Frontal Artery
A cortical branch of the middle cerebral artery supplying the ascending frontal convolution.
Vascular Smooth Muscle Tissue
Smooth muscle tissue found in the tunica media of blood vessels. It controls the diameter of blood vessels. Vascular smooth muscle tissue is autonomous and is in a partial state of contraction at all times.
Basilic Vein
One of the moderately large superficial veins of the forearm that transports blood from the hand and the medial aspect of the forearm to the axillary vein.
3p21.3
A chromosome band present on 3p
Physical location of ARHB_Gene
2: 20568463-20570829
Telomere
The terminal end of a chromosome arm which has a specialized structure and which is involved in chromosomal replication and stability. Its length is believed to be a few hundred base pairs. Telomeres undergo dramatic changes during the progression of cancer.
Telomeres
6: 53517790-53470098
Physical location of GCLC_Gene
Otolith
An embryonic cell of the inner layer of three germ layers that forms the yolk sac and gives rise to the epithelium of the alimentary and respiratory tracts and the parenchyma of associated glands.
Endodermal Cell
Endoderm Cell
A lipid bilayer enclosing a Golgi compartment.
Membrane of the Golgi Apparatus
Hamstring Muscle
Hamstring
Base of the Lung
15: 78483887-78677329
Physical location of ARNT2_Gene
Dorsal Muscle of the Back
Umbilical Cord
Extraembryonic structure that connects the fetus to the placenta. It contains two arteries and one vein.
Physical location of CCL18_Gene
17: 31415756-31422954
Anterior Ulnar Vein
A vein that extends along the ulna to the elbow joint.
A series of bones, muscles, tendons, and other tissues reaching from the base of the skull to the tailbone. The vertebral column forms the axis of the skeleton and encloses as well as protects the spinal cord and the fluid surrounding the spinal cord.
Spine
backbone
SPINAL COLUMN
Vertebral Column
Endocytotic Vesicle
A membrane-bound vesicle that is involved in transport of extracellular factors into a cell.
Endocytic Vesicle
TRIM Motif
The TRIM motif includes three cysteine-rich zinc-binding domains, a RING finger, a B-box, and a coiled-coil region. The order of the sub-domains is conserved, with the RING finger, B-box and coiled -coil domains arranged from the N to C-terminus. However, the number of B-boxes can vary. (NCI)
Tripartite Motif
RBCC/TRIM Motif
TRIM Domain
Tripartite Domain
A chromosome band present on 18q
18q12-q21
Palatine Tonsil
Middle Hemorrhoidal Artery
9: 35070013-35063835
Physical location of FANCG_Gene
Phosphorylation Site
Generally refers to amino acids residues that were covalently modified by phosphate group (PO4-). (NCI)
4: 144792221-144832172
Physical location of SMARCA5_Gene
The broadest part of the lower portion of the mediastinum. It contains the heart and the great vessels.
MEDIASTINUM, MIDDLE
Middle Mediastinum
11: 20341924-20361904
Physical location of HTATIP2_Gene
Periampullary Region
Physical location of HNRPA3_Gene
2: 177903035-177909534
DNA Binding Domain
A region of a protein that interacts with DNA. Among the various recognized structural motifs present in DNA binding domains are the helix-loop-helix and the zinc-finger.
DNA Binding Motif
Protein Motifs, DNA-Binding
19: 48451113-47443542
Physical location of ERF_Gene
The largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the blood brain barrier. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with microglia) respond to injury. Astrocytes have high- affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitter, but their role in signaling (as in many other functions) is not well understood. (MeSH)
Astrocytes
Astrocytus
Astroglia
Astrocyte
A chromosome band present on 11q
11q22.2-q22.3
2q34
A chromosome band present on 2q
17: 29670179-29672534
Physical location of CCL8_Gene
A chromosome band present on 15q
15q21-q22
Pectineus
Physical location of KRT19_Gene
17: 36938160-36933396
Centromere
The nonstaining primary constriction of a chromosome which is the point of attachment of the spindle fiber; provides the mechanism of chromosome movement during cell division; the centromere divides the chromosome into two arms, and its position is constant for a specific chromosome: near one end (acrocentric), near the center (metacentric), or between (submetacentric).
Trefoil Motif
TFF Domain
Trefoil Domain
P Domain
Trefoil
P-Type Domain
Domain found in various secretory polypeptides that has highly conserved cysteine residues that are disulfide bonded in such a way as to generate a trefoil structure (bonded 1-5, 2-4, 3-6). There are also highly conserved A, G and W residues. (The Dictionary of Cell and Molecular Biology - Online)
4: 75218935-75217793
Physical location of PPBP_Gene
Anterior Surface of the Kidney
The aspect of the kidney facing the abdominal cavity.
Proximal Phalanx of Foot
Quadrigeminal Body
Corpora Quadrigemina
12: 64869284-64928652
Physical location of IRAK3_Gene
Coccyx
A small bone located at the bottom of the spine. The coccyx is a result of 3-5 fused rudimentary vertebrae.
tailbone
Exocrine Gland Fluid or Secretion
A chromosome band present on 2q
2q35
Body of the Corpus Callosum
Sweat Gland
Intercostales Internus
Internal Intercostal Muscle
Physical location of BRCA2_Gene
13: 31787617-31871805
Terminal Bronchiole
Middle Colic Artery
8q24-qter
A chromosome band present on 8q
A chromosome band present on 12q
12q13.13
17p13
A chromosome band present on 17p
Alveolar Cell Type I
A flattened cell of the alveolar epithelium, distinguished by their greatly attenuated cytoplasm and paucity of organelles.
Type I Pneumocyte
Cartilage
A type of connective tissue composed of chondrocytes and an extracellular matrix, composed of collagen, elastin, and ground substance. There are three types of cartilage; namely elastic, hyaline, and fibrocartilage.
Cartilagenous
Nerve Plexus
Nerve Plexi
Anterior Infratentorial Cistern
An infratentorial subarachnoid cistern.
Physical location of IRF3_Gene
19: 54860926-54854641
Inner Nuclear Layer
3p21.1
A chromosome band present on 3p
Retina
A light-sensitive membrane that lines the back wall of the eyeball. The retina is continuous with the optic nerve and this way transmits optical images to the brain.
16: 87405879-87403380
Physical location of APRT_Gene
A chromosome band present on 2q
2q36
Lower Gingiva
Spleen Part
Vestibular Nuclei
Vestibular Nucleus
Chromosome 19 Distal Arm
Chromosome 19 Long Arm
Distal (long) arm of chromosome 19
19q
It refers to the chromosome status during the prophase of mitotic division. (NCI)
Genetics, Pre-Condensed Chromosomes
Pre-Condensed Chromosomes
Medial Plantar Artery
Cortex of adrenal gland
Cortical
Adrenal Cortex
The outer layer of the adrenal gland. It secretes mineralocorticoids, androgens, and glucocorticoids. (MeSH)
A chromosome band present on 17p
Chromosome 17p12
17p12
Physical location of CASP7_Gene
7: 115428952-115480652
Skene Gland
Skene's Gland
3p21.2
A chromosome band present on 3p
2q37
A chromosome band present on 2q
Bone Marrow Stem Cell with Potential to Differentiate to Granulocytic and Monocytic Lineages
A primitive, undifferentiated blood cell which can undergo division and give rise to white blood cells in the neutrophil, eosinophil, basophil or monocyte lines.
20q11-q12
A chromosome band present on 20q
Reticuloendothelial System, Lymph Node
Lymph Gland
Lymph Nodes
Lymph node proper
Lymph Node
A bean-shaped organ surrounded by a connective tissue capsule. It is part of the lymphatic system and is found throughout the body. It is composed predominantly of lymphocytes and its main function is immune protection.
Xq25-q26
A chromosome band present on Xq
Infundibular Segment of the Fallopian Tube
12: 12761576-12766570
Physical location of CDKN1B_Gene
Primitive Bone Marrow Myeloid Stem Cell
Lacrimal Canaliculus
Subserosa
Exon
The sequences of a gene that are present in the final, mature, spliced messenger RNA molecule from that gene.
Duct of the Epididymis
A hollow organ located slightly to the left of the middle portion of the chest. It is composed of muscle and it is divided by a septum into two sides: the right side which receives de-oxygenated blood from the body and the left side which sends newly oxygenated blood to the body. Each side is composed of two chambers: the atrium (receiving blood) and ventricle (ejecting blood).
Cardiac
Heart
Peripheral B-Lymphocyte of Inner Mantle Zone
Space of Fontana
A chromosome band present on 19p
19p13.1-p12
GTP Binding Domain
Associated with binding and hydrolysis of GTP, the highly conserved GTP-Binding Domain is typically found in signaling RAS-related proteins of the small GTPase superfamily. (NCI)
A chromosome band present on 12q
12q12-12q14
Notochordal Process
The primary cell of the parathyroid gland. Its contains secretory granules, large Golgi complexes, and moderate numbers of mitochondria. It produces parathyroid hormone. The cells occur in sheets interspersed with areas of fatty tissue. Occasionally the cells are arranged in follicles.
Parathyroid Gland Chief Cell
Nutrient Artery
THYROID GLAND, LEFT LOBE
The cone-like lobe of the thyroid gland that is located in the right side of the trachea.
Right Thyroid Gland Lobe
Femoral Artery Branch
11p14.3-p15.2
Part of the chromosome bands present on the short (p) arm of chromosome 11.
Epithelium consisting of multiple layers of cells in which the top layer of cells are box-shaped. It is commonly found in large gland ducts such as sweat gland ducts.
Stratified Cuboidal Epithelium
Vertebral Vein
Left Subclavian Artery
Rectus Abdominis
Remnants of nephrogenic blastema cells in the kidney following embryonic development.
Nephrogenic Rest
EF-Hand Domain
EF-Hand Motif
EF-Hand Calcium-Binding Motif
Forming a single Ca2+-binding site in many calcium-binding proteins, the basic EF-Hand Domain consists of a conserved 12-residue loop region between two perpendicular 10-12 residue alpha helices (helix-loop-helix). Ca2+ interacts with loop residues in a pentagonal bipyramidal configuration; each loop residue is important for Ca2+ coordination. Loop residues 1, 3, 5, 7, 9, and 12 (invariant Glu or Asp) are directly necessary for Ca2+ binding. Amino-acid variations at positions 1, 3, 5, 7, and 9 alter ion affinity. Single or multiple domains cause structural/functional variations. EF-hand Proteins are grouped into either regulatory/signaling or structural/buffering/transport categories. Ca2+ binding to regulatory proteins induces conformational/functional change; Ca2+ binding to structural proteins seems to provide a Ca2+ buffer. (NCI)
Lymph Node Lymphoid Follicle
A white cheese-like protective material that covers the skin of a fetus.
Vernix Caseosa
Vernix
A chromosome band present on 12q
12q13.1-q13.3
1: 92476565-92424068
Physical location of GLMN_Gene
Megakaryocyte
Very large bone marrow cells which release mature blood platelets.
Megalokaryocyte
Megakaryocytes
Megakaryocytic
Blood megakaryocyte
10q22.3
A chromosome band present on 10q
Obturator Muscle
Cranial Ridge
Right Pulmonary Artery
A system of glands that secrete fluids delivered via ducts and tubes directly to organs including the skin. Examples include the exocrine pancreas and the prostate gland.
Exocrine System
19: 56049983-56055832
Physical location of KLK3_Gene
Physical location of ARAF1_Gene
X: 47176761-47187553
WAP Motif
Whey Acidic Protein Domain
WAP Domain
The WAP (Whey Acidic Protein) Domain contains eight characteristically-spaced cysteine residues involved in disulphide bond formation and occurs in so-called 'four-disulphide core' proteins. The spatial pattern of these conserved domain cysteines suggests that the otherwise variable domain sequences may adopt a similar fold. The overall degree of domain sequence similarity is low; a few Pro and Gly residues are reasonably well conserved, as are polar/acidic residues between Cys3 and Cys4. WAP sequences are found in Whey Acidic Protein; Elafin (a human skin elastase-specific inhibitor); rat WDNM1 Protein (involved in metastatic potential); Kallmann Syndrome Protein; and guinea pig Caltrin-Like Protein II (inhibits calcium transport into spermatozoa). (NCI)
Physical location of ERCC4_Gene
16: 13921524-13949705
Primary Ossification Center
Superior Gluteal Artery
Gluteal Artery
2q31
A chromosome band present on 2q
10q11
A chromosome band present on 10q
Pulmonary Trunk
ARTERY, PULMONARY
An artery arising from the right ventricle of the heart that carries deoxygenated blood to the lungs.
Pulmonary Artery
Neural Tube
Midgut
Soluble Enzyme of the Citric Acid Cycle
An enzyme found in the mitochondrial matrix that catalyzes a reaction that is a part of the citric acid cycle, which convert the products of glycolysis into the substrates for the electron transport chain.
Soluble Enzyme of the Krebs Cycle
Proximal (short) arm of chromosome 19
19p
Chromosome 19 Proximal Arm
Chromosome 19 Short Arm
LYMPH NODE, CERVICAL
Any of the lymph nodes located in the neck.
Cervical Lymph Node
Functional Layer of the Endometrium
Right Suprarenal Vein
Roof of the Fourth Ventricle
A chromosome band present on 2q
2q32
Short region of DNA in which the frequency of the CG sequence is higher than in other regions.
CpG Island
The SANT domain is found in several transcriptional regulatory proteins identified through consistent homology to the c-MYB repeat DNA binding domain, suggesting that SANT domains also bind DNA. Folded into three alpha helices as doublets or singlets in many proteins, the SANT domain family specifically recognizes the sequence YAAC(G/T)G. The SANT domain is a repeated motif in N-CoR, the nuclear receptor co-repressor. Single copies of SANT occur in yeast nuclear chromatin remodeling proteins SWI3 (SWI/SNF transcription subunit), ADA2 (ADA adaptor/HAT complex), and a TFIIIB transcription subunit. SANT domains may mediate functional interactions with histone N-terminal tails. (NCI)
MYB-Like DNA-Binding Domain
SWI3/ADA2/N-CoR/TFIIIB Domain
SANT Domain
Intercalated Disk
2: 73967741-74001666
Physical location of AMSH_Gene
A chromosome band present on 2q
2q33
19: 18253468-18251570
Physical location of JUND_Gene
The nine cartilages of the larynx, including the cricoid, thyroid and epiglottic, and two each of arytenoid, corniculate and cuneiform. (MeSH)
Laryngeal Cartilage
Neck Muscle
Sternooccipital
A portion of the interior of the centriole that is located near the minus ends of the microtubules.
Proximal Part of the Lumen of the Centriole
A nerve that innervates the sole of the foot. This term may refer to the medial plantar nerve or lateral plantar nerve, both of which originate from the tibial nerve.
NERVE, PLANTAR
Plantar Nerve
Helicotrema
Chromosome 20 Physical Location
9: 34643932-34651884
Physical location of IL11RA_Gene
Physical location of ID2_Gene
2: 8772711-8775181
2p23.3
A chromosome band present on 2p
Physical location of AMPH_Gene
7: 38444260-38196547
Lumbar Vertebrae
Lumbar Vertebra
One of the five bones situated between the thoracic vertebrae and the sacrum in the lower part of the spine.
Thymus Gland
Thymus Proper
Reticuloendothelial System, Thymus
Thymus
A bi-lobed organ surrounded by a connective tissue capsule. It is located in the upper anterior portion of the chest, behind the sternum. It is composed predominantly of lymphocytes and fewer epithelial cells. Connective tissue septa separate the lobes into lobules. The lobules contain an outer portion (cortical zone) which is rich in lymphocytes and an inner portion (medullary zone) which is rich in epithelial cells. It is an organ essential for the development of the immune system. Its function is the maturation of the progenitor lymphoid cells to thymocytes and subsequently to mature T-cells. It reaches its greatest weight at puberty and subsequently begins to involute.
Circulatory System Part
Cardiovascular System Part
11: 71578250-71585014
Physical location of FOLR1_Gene
Thymic Capsule
Zygomatic Fossa
Head and Neck Fluids and Secretions
Head and Neck, Fluids, Secretions
Head and Neck-Fluids, Secretions
Secretions and fluids from the area of the body generally construed to comprise base of skull and facial bones, sinuses, orbits, salivary glands, oral cavity, oropharynx, larynx, thyroid, facial and neck musculature and lymph nodes draining these areas.
VA
Vertebral Artery
Sacral Plexus
Tonsillar Fossa
Pancreatico-Duodenal Artery
Esophageal Opening
12: 68150453-68255011
Physical location of FRS2_Gene
A chromosome band present on Xp
Xp11.23
Physical location of S100A8_Gene
1: 150176622-150175582
Adrenal Artery
An artery located in the abdomen that provides blood to the adrenal glands.
Suprarenal Artery
Hypoblast
Endosteum
Secretory-Stage Ameloblast
A cylindrical cell in the innermost layer of the enamel organ which deposits the organic matrix of enamel to create tooth enamel on the surface of the developing tooth.
A chromosome band present on 11p
11p12-p11
Histone Fold
A protein structural element originally identified in the core histones. It is of the helix-loop-helix type and is involved in protein-protein interactions via a "handshake" motif with a histone fold partner. Also involved in protein-DNA interactions.
Physical location of CSF3R_Gene
1: 36617602-36600737
Microtubule Bundle
It is the aggregated products of microtubules during mitosis where chromosomes line up prior to the segregation process. Many antineoplastic agents cause cytotoxicity by inducing microtubular bundle formation irreversibly. (NCI)
8: 30635274-30555575
Physical location of GTF2E2_Gene
Glomerular Basement Membrane
A sheet of amorphous extracellular material upon which the basal surfaces of epithelial cells rest and is the covering surface of a glomerular capillary, interposed between the cellular elements and the underlying connective tissue.
GBM
14q23.1
A chromosome band present on 14q
Basilar Artery Branch
Physical location of CSF2_Gene
5: 131437384-131439758
The cell membrane of a muscle cell. It is comprised of a plasma membrane coated with collagen fibers embedded in a layer of polysaccharides.
Sarcolemma
Dental Alveolus
Alveolus
Any of the bone cavities of the mandible or maxilla in which the roots of the teeth are anchored.
Tooth Socket
Clavicle
collarbone
Collar Bone
One of a pair of bones linking the scapula and the sternum. The clavicle is part of the pectoral girdle.
Nucleolar organizer regions (NORs), which are loops of DNA containing ribosomal RNA genes, have been shown to correlate with cell proliferation and malignant transformation.
Nucleolar Organizer Region
Parafascicular Nucleus of the Thalamus
Chiasma
Umbilical Vein
7p12.3-p12.1
A chromosome band present on 7p
Hemisphere of the Cerebellum
Receptor Cell
Central Zone of the Prostatic Parenchyma
Part of the functional area of the prostate that is above and in front of the transitional zone. The central zone comprises about 20-25% of the gland and is the location of about 10% of the prostate cancers found in the gland.
Zona Pellucida
2: 27351909-273738305
Physical location of CAD_Gene
URETHRA, ANTERIOR
The portion of the urethra that extends from the meatus to the membranous urethra.
Anterior Portion of the Urethra
A medial narrow structure connecting the two hemispheres of the cerebellum.
Vermis of Cerebelli
Vermis
Physical location of BAI2_Gene
1: 31898729-31861812
LUNG, RIGHT UPPER LOBE
The lobe of the right lung, situated above the horizontal fissure, which includes the apex.
Upper Lobe of the Right Lung -RUL
Upper Lobe of Right Lung -RUL
Upper Lobe of the Right Lung
Superior Lobe of the Right Lung
Lung Right Upper Lobe
Skeletal Muscle Fiber
Skeletal Fiber
Ovarian Vein
An undifferentiated cell which can undergo division and can give rise to either a megakaryocyte or a cell in the erythrocytic series.
Bone Marrow Stem Cell with Potential for Megakaryocytic and Erythroid Differentiation
Trilaminar Embryonic Disc
4q34-q35
A chromosome band present on 4q
Cuneiform Bone of the Foot
The cavity located at the upper end of the alimentary canal, behind the teeth and gums that is bounded on the outside by the lips, above by the hard and soft palates and below by the tongue.
Orally
BODY CAVITY, ORAL
Mouth
Oral
Buccal Cavity
Oral Cavity
Present at many sites of the body.
Multiple Anatomic Sites
Multiple Sites, Person
A chromosome band present on 5q
5q33.1-qter
Marginal Cusp
The membrane lining the external walls of the distal portion of the digestive tract from the small intestine to the anus. It consists of mesothelium on a connective tissue layer and it secretes a watery exudate.
Large Intestinal Serosal Surface
Gyrus Longus Insulae
16q22.1
A chromosome band present on 16q
Basal Cells
Basal Cell
Immune System
The complex group of organs like thymus, spleen, tonsils, lymphatic system, hematopoetic system and cells like lymphocytes, granulocytes, monocytes and macrophages that defends the body against infection or disease. It consists of a complex interrelated cellular, molecular and genetic component.
allergic/immunologic body system
body system, allergic/immunologic
immunologic/allergic organ system
organ system, allergic/immunologic
allergic/immunologic organ system
Physical location of CDKL2_Gene
4: 76912750-76861526
Internal Thoracic Vein
Amniotic Surface of Placenta
Amniotic Surface of the Placenta
The placenta surface in which the amniotic membrane is attached to.
Clear Cells
Clear Cell
A cell with empty-appearing cytoplasm when viewed with a light microscope.
Chromosome 12 Physical Location
19: 39547909-39583076
Physical location of GPI_Gene
Perforating Canal
Volkmann Canal
Volkmann's Canal
Microscopic channels in the compact bone that run perpendicular to the Haversian canals. They carry blood vessels from the periosteum into the bone and connect the Haversian canals with each other and the periosteum.
The endoplasmic reticulum is a network of tubular membranes within the cytoplasm of the cell, occurring either with a smooth surface (smooth endoplasmic reticulum) or studded with ribosomes (rough endoplasmic reticulum), involved in the transport of materials. (Infoplease Dictionary)
ER
Endoplasmic Reticulum
A chromosome band present on 16q
16q22.2
Head and Neck Lymph Node
Lymph Node of Head, Face and Neck
Lymph Nodes of Head, Face and Neck
A thick, oily substance produced by the sebaceous glands located in the dermis.
Sebum
A morphologically immature B-lymphocyte, once thought to represent an early stage in lymphocyte development but now known to be an activated lymphocyte that has been transformed in response to antigenic stimulation.
Precursor B-Lymphoblast
B-Lymphoblast
Space of Mall
Internal Nare
The inner portion of the nostrils of the nose.
Pancreatic Acinus
Blood Brain Barrier
BBB
Blood-Brain Barrier
Subcapsular Sinus
Lymph Node Subcapsular Sinus
The portion of the lymph node between the capsule and cortex. The subcapsular sinus receives lymph from the afferent lymph vessels and passes it to the cortical sinus.
Median Vein
Pharyngeal Pouch
A DNA sequence at which RNA polymerase binds and initiates transcription.
Promoter
Hilar Portion of the Left Hepatic Duct
22q13.3
A chromosome band present on 22q
A peritoneal fold attached to the testis during embryonic development. It is present during the scrotal descend of the testis and it subsequently undergoes atrophy.
Gubernaculum Testis
Muscular
One of the contractile organs of the body.
Muscle
Right Iliac Region
Right Inguinal Region
A lipid bilayer enclosing an endosomal compartment.
Membrane of the Endosome
Physical location of GNRH2_Gene
20: 2972268-2974391
Multipotent Stem Cell
A cell that can only differentiate to a particular type of cells (e.g. hematopoietic cells or epithelial cells). --2005
Quadratus Lumborum
Popliteal Artery Branch
Mucosa
Mucosal
Mucous Membrane
Mucous membrane.
Intercostal Artery Branch
Bronchus Elastic Tissue
Fundus
Fundic
Epiblast
Unmyelinated Nerve Fiber
A viscid fluid secreted by the synovial membrane, serving as a lubricant.
Synovial Fluid
Synovia
FLUID, SYNOVIAL
11: 303853-305272
Physical location of IFITM1_Gene
Nerve structures through which impulses are conducted from a nerve center toward a peripheral site. (MeSH)
Efferent Pathways
Efferent Pathway
The lower part of the gastrointestinal tract that includes the jejunum and ileum of the small intestine and the large intestine.
Lower Gastrointestinal Tract
GASTROINTESTINAL TRACT, LOWER
Remnants of the Notochord
Ground substance in which things are embedded or that fills a space (e.g., extracellular matrix or nuclear matrix).
Matrix
The highest portion of the femoral bone that articulates with the acetabulum.
Head of the Femur
An antigenically stimulated lymphocyte. It is a large cell with well-defined cytoplasm, a large nucleus with prominent nuclear membrane, distinct nucleoli, and clumped chromatin.
Immunoblast
Hilar Portion of the Right Hepatic Duct
External Mammary Artery
Lateral Thoracic Artery
Hand Digit 2 Phalanx
HLH Domain
Helix-Loop-Helix Motif
HLH Motif
In transcription regulators of cell cycle control, cell determination, and cell differentiation, the conserved HLH (Helix-Loop-Helix) Domain of 40-50 amino acids forms amphipathic helixes between a variable loop. HLHs typically mediate homo- or heterodimerization through interactions with self or other motifs to activate or inactivate trans-activating function. The N-helix often contains DNA-interacting basic residues; the C-helix typically contains characteristically spaced hydrophobic residues. An adjacent basic region of 15 amino acids in most HLH proteins binds to DNA. Basic (b)HLH proteins bind variants of the 'CANNTG' E-box. Proteins lacking the basic domain act as inhibitors, failing to bind DNA. bHLH proteins exhibit specific dimerization partner combinations. In calcium-binding proteins, certain invariant hydrophilic loop residues in the HLH motif bind calcium. (NCI)
Helix-Loop-Helix Domain
A skeletal muscle of the forearm originating from the posterior surfaces of the ulna and radius and the interosseous membrane.
Abductor Pollicis Longus
Special Sense Organ
Organ of Special Sense
Anatomic structures in the head responsible for special sensations rather than general sensations. This category includes the eyes, ears, nose, and tongue.
The specific parts of a protein molecule that directly participate in its interactions with a metal ion.
Metal Binding Site
Cisterna of the Golgi Apparatus
One of the flattened membrane-bound disks of the Golgi apparatus.
Base of the Pericardium
LUNG, HILUM
The wedge-shaped area at the central portion of the lung through which the bronchi, vessels and nerves enter or exit the organ.
Hilar Area of the Lung
Male Genital Organs
Male Genital Organ
The external male sexual organs.
Male Genitalia
17: 35109922-35138436
Physical location of ERBB2_Gene
Sex Cell
Germ-Line Cells
Germ Cells
Germ Cell
Initial Cell
Gametes, also known as sex cells or germ cells, are the cells that come together during fertilization or conception in organisms that reproduce sexually. Their genetic complement consists of a single set of unpaired chromosomes.
Sexual Cell
Reproductive Cells
reproductive cell
Gametes
The pigmented layer of the eyeball between the tough, white outer coat of the eye and the retina.
Uvea
Uveal Tract
Tunica Vasculosa of Eyeball
Iris, Ciliary Body and Choroid
Hypervariable Loop
Complimentarity Determining Region
CDR
Within the variable domain of an antibody molecule are three regions called hypervariable regions, areas of high sequence diversity. These regions form the surfaces that are responsible for antigen binding interactions. Also known as complementarity determining region or hypervariable loop.
Immunoglobulin Hypervariable Region
Maxillary Vein
Internal Maxillary Vein
Lamina Spiralis Ossea
Gastric Glandular Cell
A cell found in the gastric mucosa that produces and secretes digestive enzymes and acid.
Tuber Cinereum
Brain Gray Matter
The areas of the brain composed of neurons and (in contrast to the white matter) unmyelinated nerve fibers.
8p11.21
A chromosome band present on 8p
A chromosome band present on 7q
7q11.23
Left Brachiocephalic Vein
Decidua Basalis
Lobus Spigelii
The pigmented circle or ring of skin that surrounds the nipple.
Areola
17q21-q23
A chromosome band present on 17q
Canal for Tensor Tympani
Limbic System
Short Tandem Repeat
Area of repetitive DNA within the genome consisting of multiple, end-to-end copies of a short DNA sequence usually comprised of di-, tri-, or tetranucleotide repeat units.
Simple Sequence Repeat
STR
Foot Phalanx
A bone of the foot.
Phalanx of the Foot
Phalanx of Foot
Phalanges of Foot
Posterior Spinal Artery
1: 204472910-204448280
Physical location of CD34_Gene
Lacrimal Artery
Tongue
The muscular organ located in the floor of the mouth and serving as the principal organ of taste and modification of the voice in speech.
Skin of the Lip
Skin of Lip, NOS
Skin of Lip
A chromosome band present on 17q
17q21-q22
Fenestrated Capillary
Retinal Pigment Epithelium
RPE
A continuous, insulating monolayer of cuboidal/columnar epithelium which extends from the margins of the optic nerve head to the ora serrata where it is continuous with the pigment epithelium of the pars plana. This cell layer has many physical, optical, metabolic/biochemical and transport functions which play a critical role in the normal visual process, including acting as a selective filter to determine what nutrients reach the retina from the choroid.
A nerve cell with two processes.
Bipolar Neuron
Bipolar Neurons
X: 152806189-152796809
Physical location of IRAK1_Gene
Liver Acinus
The smallest functional unit of the liver, comprising all of the liver parenchyma supplied by a terminal branch of the portal vein and hepatic artery; typically involves segments of two lobules lying between two terminal hepatic venules.
The skin or integument surrounding the abdomen.
Abdominal Skin
Abdomen Skin
A natural prolongation or projection from a part of an organism either animal or plant; a part that is joined to something larger.
Appendage
13q22-q34
A chromosome band present on 13q
Lysosome
A class of morphologically heterogeneous cytoplasmic membrane-bound vesicle in animal and plant tissues characterized by their content of a wide variety of glycoprotein hydrolytic enzymes active at an acid pH and the structure-linked latency of these enzymes. The intracellular functions of lysosomes depend on their lytic potential. The single unit membrane of the lysosome acts as a barrier between the enzymes enclosed in the lysosome and the external substrate. The activity of the enzymes contained in lysosomes is limited or nil unless the vesicle in which they are enclosed is ruptured. Such rupture serves to digest exogenous material, such as bacteria, as well as effete organelles of the cells and is supposed to be under metabolic (hormonal) control.
Physical location of HKR3_Gene
1: 6574377-6583605
One of 12 vertebrae in the human vertebral column. The thoracic vertebrae are situated between the seventh cervical vertebra down to the first lumbar vertebra.
Thoracic Vertebrae
Thoracic Vertebra
Tissue composed of three layers- epidermis, dermis and subcutis which protect underlying muscles and organs. Skin is used for insulation, vitamin D production, sensation, and excretion through sweat.
Skin Tissue
Laryngeal Mucous Salivary Gland
Chromosome 22 Physical Location
A functional unit of the kidney consisting of a renal pyramid and the renal cortex surrounding it.
Kidney Lobe
Brain Infundibulum
Sensory Ganglia
Clusters of neurons in the somatic peripheral nervous system which contain the cell bodies of sensory nerve axons. Sensory ganglia may also have intrinsic interneurons and non-neuronal supporting cells. (MeSH)
Sensory Ganglion
Minute branching canals in the tooth dentin that contain filamentous protoplasmic processes of the odontoblasts and extend radially from the pulp to the dentoenamel junction.
Dentinal Canal
Dentinal Tubule
Posterior Wall of the Oropharynx
Posterior Wall of Oropharynx
Named locations of or within the body.
Anatomic Site
Anatomic Sites
Site
Anatomic Location
Location
Thoracic Aorta Branch
The part of the eye anterior to the lens, including but not limited to the anterior chamber, cornea and related structures.
Anterior Eye Segment
Pronephric Duct
Eyelid Skin
An artery that joins the two anterior cerebral arteries.
Anterior Communicating Artery
1: 94719336-94706894
Physical location of F3_Gene
10: 98021316-97941447
Physical location of BLNK_Gene
Bladder
Urinary System, Bladder
Urinary Bladder
The distensible sac-like organ that functions as a reservoir of urine, collecting from the kidneys and eliminating via the urethra.
Germinal Center
The activated center of a lymphoid follicle in secondary lymphoid tissue where B-Lymphocytes are stimulated by antigens and Helper-Inducer T-Lymphocytes are stimulated to generate memory cells.
Lens Pit
Choroid Plexus of the Lateral Ventricle
Dendritic clear cells in the epidermis, containing distinctive granules that appear rod- or racket-shaped in section, but lacking tonofilaments, melanosomes, and desmosomes; they carry surface receptors for immunoglobulin (Fc) and complement (C3), and are believed to be antigen fixing and processing cells of monocytic origin; active participants in cutaneous delayed hypersensitivity.
Langerhans Cell
Non-Neoplastic Langerhans Cell
Langerhans Cells
1p35.1-p36.23
A chromosome band present on 1p
The inner layer of the connective tissue that seals the joint.
TISSUE, SYNOVIAL
Synovium
Synovial Membrane
A chromosome band present on Xq
Xq22-24
A connective tissue cell that develops into a fat cell.
Lipoblast
A muscle located in the back of the lower leg beneath the gastrocnemius muscle. Its actions involve the flexion of the ankle joint and standing.
MUSCLE, SOLEUS
Soleus
Physical location of CYP11A1_Gene
15: 72447020-72417157
A region of the brain located in the frontal lobe of the dominant hemisphere; it plays an essential role in the motor control of speech.
Area of Broca
Posterior Cardinal Vein
1: 189276582-189280811
Physical location of RGS1_Gene
A chromosome band present on 11q
11q14.2
A long curved fold located in the medial surface of the cerebral hemisphere.
Cingulate Gyrus
Physical location of BIRC7_Gene
20: 61337721-61342299
6: 33655959-33648307
Physical location of BAK1_Gene
A chromosome band present on Xp
Xp11.22
A chromosome band present on 14q
14q21.3
Axillary Nerve
15: 79262255-79392157
Physical location of IL16_Gene
Angioblast
A pluripotent cell that can develop into a vascular endothelial cell.
Angioblastic
Sacrococcygeal Joint
Lymph Node Capsule
Common Carotid Artery Branch
Fibrillin Microfibrils
A filamentous extracellular structure that is rich in the glycoprotein, fibrillin-1, and found in connective tissues where it can act as a scaffold for elastin.
Totipotent stem cells, such as the product of fertilization of an ovum and its progeny, are stem cells that have total potency to form an entire mature organism, e.g., a human being, although only if placed in a woman's uterus.
Totipotent Stem Cell
Gallbladder Body
11q14.1
A chromosome band present on 11q
Cranium
BONE, SKULL
Bone, Cranial
Skull
The bones that form the head, made up of the bones of the braincase and face.
Simple Cuboidal Epithelium
Epithelium composed of a single layer of box-shaped cells found lining glands, ducts of glands and kidney tubules. This type of epithelium is efficient at secretion and absorption.
Supramarginal Gyrus
An epithelial cell which may release secretions to a free epithelial surface (exocrine) or to the circulatory system (endocrine).
Glandular Cell
8p11.23
A chromosome band present on 8p
Tracheoesophageal Fold
8: 56954926-57085685
Physical location of LYN_Gene
A chromosome band present on 12q
12q24.3
Deep Abdominal Muscle
TGN
Trans-Golgi Network
A network of membrane components where vesicles bud off the Golgi apparatus to bring proteins, membranes and other components to the plasma membrane, secretory vesicles and endosomes.
Cleft
A split or indentation in something.
Lens Capsule
Inner Enamel Epithelium
The inner most layer of the enamel organ. It is derived from the ectoderm of the dental lamina and differentiates into ameloblasts that secrete the enamel of the root crown.
A chromosome band present on 17q
17q25.1
8: 104380276-104414270
Physical location of FZD6_Gene
Cord
A long slender flexible material usually consisting of several strands woven or twisted together; a part of the body resembling a cord.
22q11-q13
A chromosome band present on 22q
1p21-p13
A chromosome band present on 1p
21q11.2
A chromosome band present on 21q
A chromosome band present on 8p
8p11
Labia Minus
Labia Minora
Labium Minus
One of the two longitudinal folds of skin located between the labia majora.
Pelvic Lymph Nodes
Any lymph node within the abdominal pelvic region.
Pelvic Lymph Node
Adductor Group of the Leg
MUSCLE, ADDUCTOR
A group of muscles causing movement of the leg towards the midline of the body.
Blastula
Blastosphere
An embryo made up of two groups of cells. One group will develop into the fetus and the other will become the placenta.
Blastocyst
Splenic Red Pulp
Splenic pulp seen grossly as a reddish brown substance, due to its abundance of red blood cells, consisting of splenic sinuses and the tissue intervening between them (splenic cords).
Red Pulp
Physical location of BMP3_Gene
4: 82309298-82331904
Seminal Vesicle Epithelium
Otic Placodes
Reserve Cell
Superior Sagittal Sinus
Greater Sagittal Sinus
Sagittal Sinus, Greater
Sagittal Sinus, Superior
An intracranial venous sinus that lies in a superior and midline location above the interhemispheric fissure along the superior border of the falx cerebri of the brain. The sinus receives blood from the cerebral veins and drains posteriorly into the lateral sinuses of the brain, which in turn drain into the internal jugular veins.
The walnut shaped accessory sex gland of the male reproductive system. It is located in the pelvis just below the bladder, surrounding the prostatic part of the urethra. The prostate gland secretes a fluid which is part of the semen.
Human Prostate
Genital System, Male, Prostate
Human Prostate Gland
Prostatic Gland
Prostate
Prostate Gland
Posterior Nucleus of the Thalamus
Syncytiotrophoblast
8p12
A chromosome band present on 8p
Glomerular Mesangial Cell
Cells found within the glomerular lobules of mammalian kidney, where they serve as structural supports, may regulate blood flow, are phagocytic and may act as accessory cells, presenting antigen in immune responses.
Sulcus Centralis Cerebri
Sulcus Centralis
Renal Cortex
Cortical Portion of the Kidney
KIDNEY, CORTEX
Cortical
Cortical Portion of Kidney
Physical location of BIRC5_Gene
17: 73721944-73732372
Basal Cerebral Vein of Rosenthal
Internal Anal Sphincter
Physical location of IMPDH2_Gene
3: 49041832-49036767
10: 22650146-22660194
Physical location of BMI1_Gene
A chromosome band present on 11q
11q23-q24
Scrotum
The musculocutaneous pouch that encloses the testicles.
Striated Border
Pedicel
Foot Process
Anterior Surface of the Epiglottis
The lingual or upper surface of the epiglottis.
Anterior Surface of Epiglottis
Neurons which convey sensory information centrally from the periphery. (MeSH)
Neurons, Sensory
Afferent Neuron
Sensory Cell Afferent Neuron
Neurons, Afferent
Sensory Neuron
3: 95821-98085
Physical location of CCRL2_Gene
Bile Salt
Sigmoid Artery
Oligodendrocytus
Oligodendroglia Cell
Oligodendrocytes
Oligodendroglia
A class of neuroglial (macroglial) cells in the central nervous system. Oligodendroglia may be called interfascicular, perivascular, or perineuronal satellite cells according to their location. The most important recognized function of these cells is the formation of the insulating myelin sheaths of axons in the central nervous system. (MeSH)
Oligodendrocyte
Putative DNA/Chromatin Binding Motif 1
Putative DNA/Chromatin Binding Motif 1 is a protein containing three cysteine-rich zinc-binding PHD/LAP domains, a DNA-binding domain found in the Drosophila dead ringer gene product, five putative nuclear localization signals, and other conserved regions of unknown function. The protein may be expressed as a 170-kD protein in the nucleus and shares 56% overall amino acid sequence identity with RBBP2, which plays an important role in RB tumor suppressor regulation. (from OMIM 605393 and NCI)
PUT 1
7p12-p11.2
A chromosome band present on 7p
GT Repeat
CA/GT Repeat
GT/CA Repeat
A dinucleotide repeat consisting of (CA/GT)n.
CA Repeat
Hamate
Unciform Bone
Uncinate Bone
The medial bone in the distal row of carpal bones.
Hamate Bone
A chromosome band present on 19q
19q13.1-qter
Base of the Prostate
Base of Human Prostate
The uppermost part of the prostate gland adjacent to the bladder wall.
Cisterna of the Endosome
Taste Bud Cells
Any of the three types of the cells that constitute the taste bud. They are classified as neuroepithelial (sensory) cells, supporting cells, and basal cells.
Taste Bud Cell
Direct Pyramidal Tract
Suprasellar
Suprasellar Region
The region above or over the sella turcica.
SET domains appear to be protein-protein interaction domains. SET domains mediate interactions with a family of proteins that display similarity with dual-specificity phosphatases (dsPTPases). The SET domain genes are widely represented in the eukaryotic genomes. Proteins bearing the widely distributed SET domain (ca. 130 amino acid) contribute to epigenetic mechanisms of gene regulation by methylation of lysine residues in histones and other proteins. The SET domain appears generally as one part of a larger multidomain protein. It appears that the varied domains that occur together with the SET domain are involved in recognizing protein substrates and ''reading'' histone tails in order to dictate which (if any) of their multiple lysine residues should get methylated. (From Pfam PF00856)
SET Domain
1: 65064007-65012229
Physical location of JAK1_Gene
Brain Part
Labium Majus
One of the two longitudinal folds of skin that form the lateral boundary of the vulva. It extends from the mons pubis to the perineum.
Labia Majus
Labia Majora
Crus Cerebri
Any of the teeth located in the upper jaw.
Upper Jaw Tooth
The wall of the cochlear duct, which separates it from the scala tympani. It vibrates in response to sound, exciting the hair cells and supports the organ of Corti.
Basilar Membrane of the Membranous Canal of the Cochlea
9p22
A chromosome band present on 9p
Hair Part
The liquid secreted by the sweat glands, having a salty taste and a pH that varies from 4.5 to 7.5. Sweat produced by the eccrine sweat glands is clear with a faint characteristic odor, and contains water, sodium chloride, and traces of albumin, urea, and other compounds. Its composition varies with many factors, e.g., fluid intake, external temperature and humidity, and some hormonal activity. Sweat produced by the larger, deeper, apocrine sweat glands of the axillae contains, in addition, organic material which on bacterial decomposition produces an offensive odor.
PERSPIRATION
Sweat
Placental Membrane
Chromosomal bands observed after staining with specific dyes. The band pattern is the result of differential interactions between the dye and nonadjacent chromosomal regions.
Chromosome Band
Chromosomal Bands
Chromosomal Band
band
A parathyroid gland embedded within the thyroid gland parenchyma.
Intrathyroidal Parathyroid
Microsatellite Repeat
A variety of simple di- , tri- , tetra-, and pentanucleotide tandem repeats that are dispersed in the euchromatic arms of most chromosomes.
Microsatellite
Microsatellite Repeats
Microsatellites
Physical location of IRF1_Gene
5: 131854326-131846679
Free Ribosome
A ribosome that is not associated with the membrane of the rough endoplasmic reticulum.
A chromosome band present on 9p
9p21
18: 59185438-59148813
Physical location of FVT1_Gene
A chromosome band present on 14q
14q23-q24.1
Small glands located within the epidermis, and associated with the hair follicle, that produce and secrete an oily substance that lubricates the skin and hair.
Sebaceous Gland
GLAND, SEBACEOUS
Named areas of the body.
Body Region
Anatomic Region
X: 153339173-153323310
Physical location of G6PD_Gene
8: 82355340-82359563
Physical location of FABP5_Gene
Foot Digit 2 Phalanx
Superior Rectus Muscle
Plus End of the Actin Filament
Plus End of Actin Filament
Barbed End of Actin Filament
Barbed End of the Actin Filament
The end of an actin filament that is polymerizing at a faster rate.
Intrapulmonary Bronchus
A bronchial branch that is located within the lung tissue.
The anterior and superior part of a human bearing the mouth, the brain and sensory organs.
Head
A chromosome band present on 9p
9p24
Inferior Cerebellopontine Cistern
Lateral Cerebellomedullary Cistern
Common Femoral Artery Branch
17q25.3
A chromosome band present on 17q
Fusiform Gyrus
Occipital-Temporal Gyrus
Tissue composed of the renal cortex and the renal medulla. The basic functional unit of renal tissue is the nephron.
KIDNEY
Renal Tissue
Somite
Ilio-Lumbar Artery
Iliolumbar Artery
Physical location of RAPGEF1_Gene
9: 131642479-131481711
Seventh Cranial Nerve
NERVE, FACIAL
Facial Nerve
The 7th cranial nerve. The facial nerve has two parts, the larger motor root which may be called the facial nerve proper, and the smaller intermediate or sensory root. Together they provide efferent innervation to the muscles of facial expression and to the lacrimal and salivary glands, and convey afferent information for taste from the anterior two-thirds of the tongue and for touch from the external ear. (MeSH)
Physical location of GMNN_Gene
6: 24883143-24894257
Physical location of WNT6_Gene
2: 219548961-219564457
A chromosome band present on 15q
15q25-q26
Nonspecific Immune Cell
A chromosome band present on 9p
9p23
Second Pharyngeal Arch
Hyoid Arch
Auditory Striae
Striae Medullares
Gastric Gland
Fundic Gland
4: 123735485-123730230
Physical location of IL2_Gene
Obex Region
BRAIN, OBEX
The location of the brain that corresponds to the narrowing of the fourth ventricle into the central canal of the spinal column.
Superior Parietal Convolution
Nucleus
Cell Nucleus
Nucleic
A body within the cell, surrounded by a membrane, within which lie the chromosomes, one or more nucleoli, combined with proteins, and exhibits mitosis.
Interpenduncular Cistern
Metaphase Plate
The plane of the spindle approximately equidistant from the two poles along which the chromosomes are lined up during mitosis or meiosis.
A chromosome band present on 10q
10q26.13
A structure consisting of something wound in a continuous series of loops.
Helix
Body of the Epididymis
Neuroendocrine Cell
An endocrine cell that produces and releases hormones and regulatory proteins such as neurotransmitters and neuropeptide hormones. This type of cell enables autocrine communication with paracrine and endocrine cells throughout the body.
Neuroendocrine Cells
8q24
A chromosome band present on 8q
Subclavicular Node
Subclavicular Lymph Node
Deltopectoral Lymph Node
Deltopectoral Node
Infraclavicular Node
Infraclavicular Lymph Node
A lymph node located in the area below the clavicle.
Male germ cells derived from spermatogonia and developing into spermatids. (MeSH)
Spermatocyte
Spermatocytes
Spermiocytes
Body Fluid or Substance
Material produced by living organisms; it can be a necessary constituent of, or product of an organismal process.
Biological Substance
Body Fluids and Substances
Fluids
Body Fluids or Substances
FLUID
The portion of the hair that is enclosed within the hair follicle.
Hair Root
Thyroid Gland Tissue
GLAND, THYROID
The tissue that forms the thyroid gland. Its main component is the thyroid follicle.
Blastemal Cell
A chromosome band present on 5p
5p15.1-p14
Inferior Temporal Convolution
Inferior Temporal Gyrus
Physical location of CBFB_Gene
16: 65620551-65692462
A complete cylindrical microtubule that is part of a microtubule doublet in cilia.
A-Microtubule
2p21
A chromosome band present on 2p
A chromosome band present on Xp
Xp11.2
1p36.13-p36.11
A chromosome band present on 1p
Brachial Lymph Node
LYMPH NODE, BRACHIAL
An axillary lymph node along the brachial vein.
Sacral Nerve
15q15-q21.1
A chromosome band present on 15q
11: 67645434-67576904
Physical location of CHK_Gene
Gray Commissure
12: 4253199-4284777
Physical location of CCND2_Gene
Odontoid Process
Odontoid Peg
A bony tooth-like process projecting from the second cervical vertebra. It serves as the structure that supports the rotation of the first cervical vertebra.
Lower-Outer Quadrant of the Breast
Lower-outer Quadrant of Breast
The quarter of the breast which is inferior and lateral.
Utriculosaccular Duct
Respiratory Bronchiole
2q21
A chromosome band present on 2q
Physical location of LEFTB_Gene
1: 222383571-222380718
The entire nerve apparatus, composed of a central part, the brain and spinal cord, and a peripheral part, the cranial and spinal nerves, autonomic ganglia, and plexuses.
Nervous System
Body System, Neurologic
Neurologic Body System
Organ System, Neurologic
Neurologic Organ System
Umbilical Artery
Internal Parieto-Occipital Fissure
A chromosome band present on 6p
6p21.1-p21.3
Stroma of the Ovarian Cortex
Physical location of BDKRB2_Gene
14: 95740950-95780542
4: 1232621-1195118
Physical location of CTBP1_Gene
Physical location of ABI2_Gene
2: 204018668-204117838
1: 47367791-47361281
Physical location of MAP17_Gene
A muscle in the upper arm. Its action involves the rotation of the arm and the flexing of the elbow.
Biceps
MUSCLE, BICEPS BRACHII
Biceps Brachii Muscle
A cell derived from stem cells in the bone marrow. It is a maturing T lymphocyte that expresses a gamma-delta antigen specific surface receptor (TCR). These cells exert major histocompatibility-unrestricted natural cytotoxicity against several types of solid tumors and some leukemias and lymphomas. They are also involved in the immune response to certain infections and are able to mediate antibody-dependent cytotoxicity and are not alloreactive.
Immature Peripheral Gamma/Delta Cell of Cytotoxic Type
8q22
A chromosome band present on 8q
GLAND, PARATHYROID
Parathyroid gland tissue consists of three primary cell types - chief cells, oxyphil cells and clear cells. These glands are usually located in close proximity to the thyroid gland.
Parathyroid Gland Tissue
Liver Cells
Hepatic Cells
Hepatic Parenchymal Cell
Hepatocytes
A parenchymal liver cell.
Hepatocyte
A chromosome band present on 2p
2p23
Lumbar Portion of Spinal Cord
SPINAL CORD, LUMBAR
The portion of the spinal cord located in the lumbar region.
Lumbar Spinal Cord
8: 26778839-26661584
Physical location of ADRA1A_Gene
Kupffer Cells
Kupffer's Cell
Stellate Sinusoidal Macrophage
Large star-shaped or pyramidal cells with a large oval nucleus and a small prominent nucleolus. These intensely phagocytic cells line the walls of the sinusoids of the liver and form a part of the reticuloendothelial system.
Kupffer Cell
Centroblast
Large Non-Cleaved Follicle Center Cell
An activated B-lymphocyte found in the germinal centers. It has a large nucleus without clefts, finely dispersed chromatin, and a rim of basophilic cytoplasm.
12: 6626841-6617503
Physical location of ACRBP_Gene
The thin wall between the two nasal cavities.
Nasal Septum
A chromosome band present on 7q
7q33-q35
NAD-Binding Domain
The Gly-rich NAD-Binding Domain (often N-terminal) is often found in metabolic enzymes involved in glycolysis, glyconeogenesis, and the citric acid cycle, such as GAPDH (glyceraldehyde-3-phosphate oxidation and phosphorylation), lactate dehydrogenases (lactate to pyruvate conversion), and malate dehydrogenases (malate to oxaloacetate interconversion). (NCI)
NAD-Binding Fold
Anterior Annular Ligament
A ligament present in the wrist and the ankle. In the wrist it is located over the carpus and in the ankle across the front of the leg and over the joint.
Continent Reservoir
The anterior, usually ovoid, nucleus-containing part of spermatozoa. (MeSH)
Head of the Spermatozoon
Sperm Head
Decidual Cell
An endometrial fibroblast that differentiates during pregnancy in response to the implanting embryo by accumulating lipid and glycogen. It is polygonal, possesses a large, vesicular nucleus and is believed to secrete placental prolactin. The decidual cells form a tightly adherent, massive cellular matrix that first surrounds the implanting embryo and later occupies most of the endometrium.
Physical location of GNRH1_Gene
8: 25337836-25332693
2p24
A chromosome band present on 2p
Physical location of ARHC_Gene
1: 112961762-112955795
5q14.3
A chromosome band present on 5q.
Hand Digit 3 Phalanx
Vaginal Squamous Epithelium
A chromosome band present on 7q
7q33-q34
Superior Mesenteric Artery Branch
External Jugular Vein
12q24.11
A chromosome band present on 12q
Gastric Submucosa
Left Common Iliac Artery
19: 60573626-60567569
Physical location of IL11_Gene
Tonsillar Capsule
A chromosome band present on 2p
2p25
6p25-p23
A chromosome band present on 6p
Thoracoacromial Artery
Acromial Thoracic Artery
An axillary artery branch that divides in four branches (pectoral, acromial, clavicular, and deltoid branch) supplying the regions of the shoulder and upper chest.
Pharyngeal Groove
12q13-q14
A chromosome band present on 12q
Dorsal Root of the Spinal Nerve
ARID Domain
The approximately 100-amino acid ARID (AT-Rich Interaction Domain) DNA-binding domain occurs in some transcriptional regulators (and perhaps modifiers of chromatin structure) involved in embryonic development, cell lineage, and cell cycle control. The domain shows more diversity in structure and function than the highly conserved sequence suggests: at least six alpha helices separated by beta-strands, loops, or turns. Although Bright, dead ringer, and MRF-2 preferentially bind to AT-rich sites, DNA binding of ARID-proteins is not necessarily sequence specific; ARID protein p270 of the SWI-SNF complex exhibits non-specific DNA binding activity. ARID family proteins may be involved in a wide range of DNA interactions. Inappropriate expression of ARID proteins is increasingly implicated in tumorigenesis.
BRIGHT Domain
AT-Rich Interactive Domain
AT-Rich Interaction Domain
Part of the chromosome bands present on the long (q) arm of chromosome 3.
3q13.2
SCR Repeat
Complement Control Protein (CCP) Module
Short Consensus Repeat
Sushi domains, also known as Complement control protein (CCP) modules or short consensus repeats (SCR), exist in a wide variety of complement and adhesion proteins. The structure is known for this domain, it is based on a-sandwich arrangement; one face made up of three-strands hydrogen-bonded to form a triple-stranded region at its center and the other face formed from two separate strands. (From Pfam PF00084)
Sushi Domain
External Parieto-Occipital Fissure
A chromosome band present on 9p
9pter-p22.1
Pre-Thymocyte
COLON, RIGHT
Right Colon
The proximal segment of the large intestine that is located in the right side of the abdominal cavity. It includes the cecum (with the attached appendix) and the ascending colon.
Serratus Dorsalis Caudalis
11: 62445588-62432728
Physical location of CHRM1_Gene
External Acoustic Meatus
External Auditory Canal
Auditory Canal, External
That part of the ear canal external to the ear drum
A chromosome band present on Xp
Xp11.2-p11.4
HT-Zip Domain
Bipartite DNA binding domain containing a helix-turn and a leucine zipper.
8q21
A chromosome band present on 8q
Lower Clivus
Physical location of APPBP2_Gene
17: 55958362-55875302
Optic Cup
The anterior portion of a deep fissure or furrow on the medial surface of the cerebral cortex.
Anterior Part of the Calcarine Fissure
Muscle Fibers, Slow-Twitch
Skeletal muscle fiber, type I
Muscle Fibers, Intermediate
Muscle Fibers, Type I
Skeletal muscle fibers having low myofibrillar ATPase activity, low glycogen content, and high myoglobin content, high mitochondrial oxidative enzyme activities, and an intermediate mitochondrial content which produce a slow twitch and are fatigue-resistant. (MeSH)
12q24.13
A chromosome band present on 12q
Sulcus Terminalis
Marginal Zone of the Lymph Node
Marginal Zone of Lymph Node
Chromosome X Physical Location
Lamellar Body
Long Bone Metaphysis
Metaphysis
A chromosome band present on 5q
5q13.1
12q24.1
A chromosome band present on 12q
A chromosome band present on 2q.
2q22
Buccinator
A cartilage-forming cell derived from a mesenchymal cell. The chondroblast secretes hyaluronidase, chondroitin sulfates, and collagen II to form a collagen matrix. It differentiates into a chondrocyte.
Chondroblast
A chromosome band present on 2q
2q31.2-q33.1
8q22-q23
A chromosome band present on 8q
Organelle
Cell part which consists of macromolecules aggregated into discrete structures in the protoplasm. (Digital Anatomist Foundational Model)
Cytoplasmic Organelle
Precursor Adenohypophysial Cell
Common Iliac Artery
8: 21702292-21688429
Physical location of GFRA2_Gene
Lactotroph Cell
Lactotrope Cell
PRL Cell
Prolactin Cell
Lactotroph
Mammotrope
A layer of phospholipids and protein found on neuronal axons. This structure acts as an electrical insulator that allows nerve impulses to travel faster by increasing the resistance and decreasing the capacitance over that found in unmyelinated nerve fibers.
Myelin
Myelinated
Myelin Sheath
Cornea
A dome-shaped, transparent, avascular tissue covering the front of the eye. It is composed of five layers: squamous epithelium, Bowman's membrane, stroma, Descemet's membrane, and endothelium. Refraction of light contributing to eye's focusing ability is its characteristic function. It contains unmyelinated nerve endings which are responsible for the high sensitivity of the tissue.
EYE, CORNEA
12q24.2
A chromosome band present on 12q.
2q23
A chromosome band present on 2q
A chromosome band present on 4q
4q25-q31
Endocrine Organs
Endocrine Gland
Ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions.
A chromosome band present on 6q.
6q13
Any anatomical feature created by surgery. This includes structures created to mimic the function of a structure removed by surgery or destroyed by disease.
Surgically Created Structure
A single-cusped (pointed) and usually single-rooted tooth located between the incisors and premolars.
TOOTH, CANINE
Canine Tooth
6p21.2
A chromosome band present on 6p
A sheath that envelops a tendon.
Tendon Sheath
Tenosynovium
Unspecified Site
Research that isn't focused on a specific site.
Unspecified Anatomic Sites
Microvillus
A finger-like projection of the plasma membrane found in epithelial cells that increases the surface area of the apical domain of the epithelium. It is comprised of plasma membrane that is supported by longitudinal actin filaments that are crosslinked by fimbrin and villin.
Sternomastoid Muscle
Sternocleidomastoid Muscle
1: 203459184-203465879
Physical location of IL24_Gene
Xq22
A chromosome band present on Xq
6q12
A chromosome band present on 6q
Wrist Skin
3q21-q23
A chromosome band present on 3q
Lactiferous Duct
A channel conveying the milk secreted by the lobes of the breast to and through the nipple.
Brain Ventricle
Ventricles
Ventricle of Brain
Ventricle, Brain
Ventricle
Ventricles, Brain
The four connected cavities (hollow spaces) centrally located within the brain that connect posteriorly with the central canal of the spinal cord.
3: 185762289-185782898
Physical location of EPHB3_Gene
Intestinal Secretion
A chromosome band present on 12q
12q13.2-q13.3
A chromosome band present on 6p
6p21.3
Lens
A biconvex transparent structure of the eye through which light is focused on the retina. The lens sits behind the iris and is supported by the zonule, which connects it to the ciliary body. The lens is an avascular structure.
EYE, LENS
Ocular Lens
Crystalline Lens
Lens Of Eye
Body of the Penis
Body of Penis
Activated Mature Gamma/Delta T-Lymphocyte with a Cytotoxic Phenotype
A mature lymphocyte whose T cell receptor, a gamma polypeptide chain linked by a disulfide bridge to a delta polypeptide chain, has recognized specific foreign antigens and self MHC antigens. This type of cell is most often found in the gut and epidermis.
1p31-p22
A chromosome band present on 1p
Hepatic Diverticulum
A chromosome band present on 12q
12q13-q15
Gastric Juice
Gastric Secretion
The digestive secretions of the gastric glands in the stomach, consisting mainly of pepsin, hydrochloric acid, rennin, and mucin.
Muscularis Mucosa
A thin layer of smooth muscle fibers found as a part of the tunica mucosa in the gastrointestinal tract and urinary bladder deep to the lamina propria mucosae.
4q31.3-q33
A chromosome band present on 4q
Superior Parathyroid Gland
Myofilament
Fibrillar protein polymers found in the contractile apparatus of muscle cells.
Embryonic Musculoskeletal System
Muscle of the Tympanum
Middle Temporal Sulcus
Central Canal
Central Canal of Spinal Cord
Follicular
Follicle
Any small spherical group of cells containing a cavity.
Physical location of EWSR1_Gene
22: 27988825-28021059
A cone-shaped structure of the kidney. It is located in the medullary portion of the kidney (pyramid of Malpighi) or the cortical portion of the kidney (pyramid of Ferrein).
Renal Pyramid
1p31.1
A chromosome band present on 1p.
Torcular Herophilli
Nucleosome core particle consists of the 146 base pair highly protected DNA segment and its bound histone octamer (two of each histones H2A, histone2B,, H3 and H4). Nucleosome core particle, linker DNA and histone H1 comprise one structural unit of chromatin, nucleosome. (NCI)
Nucleosome Core Particle
Spool
Nucleosome Core
Core Particle
Protein Spool
19: 18058697-18031704
Physical location of IL12RB1_Gene
Tarsal Joint
JOINT, TARSUS
Physical location of KDR_Gene
4: 55832690-55785577
Diaphragm Part
A chromosome band present on 6p
6p21.1
Physical location of GCLM_Gene
1: 94086987-94066034
Digit
A finger or toe in human beings or corresponding part in other vertebrates.
Digital
Connective Tissue Fiber
Physical location of LTB4R_Gene
14: 23852357-23855992
A chromosome band present on 6p
6p21.3-p21.2
A triangular-shaped unit of hepatic tissue, containing portions of three adjacent hepatic lobules with the portal canal in the center. The portal canal is composed of the portal vein, hepatic artery, bile ductile, and lymph vessel. There is a central vein at the apex of each peripheral corner. Blood flows from the portal vein and hepatic artery towards the central vein. Bile flows in the opposite direction, towards the portal canal.
Portal Lobule
Physical location of BRS3_Gene
X: 135295645-135300118
Cerebellar Peduncle
One of three pairs of nerve fiber bundles that originate from the cerebellum and link it to the brainstem.
Many calcium-binding proteins belong to the same evolutionary family and share a type of calcium-binding domain known as the EF-hand. This type of domain consists of a twelve residue loop flanked on both side by a twelve residue alpha-helical domain. In an EF-hand loop the calcium ion is coordinated in a pentagonal bipyramidal configuration. The six residues involved in the binding are in positions 1, 3, 5, 7, 9 and 12; these residues are denoted by X, Y, Z, -Y, -X and -Z. The invariant Glu or Asp at position 12 provides two oxygens for liganding Ca (bidentate ligand). (From InterPro IPR002048)
Calcium-Binding Domain
Calcium-Binding Motif
BONE, RIB
Rib
Any one of the paired bones, 12 on either side, extending from the thoracic vertebrae toward the median line on the ventral aspect of the trunk. The long curved bones which form the rib cage. Generally, ribs 1 to 7 are connected to the sternum' by their costal cartilages and are called true ribs, whereas ribs 8 to 12 are termed false ribs.
A covering fold of skin, often used alone to designate the preputium penis.
Preputium Penis
Prepuce
T-Lymphocyte
Thymus-Dependent Lymphocytes
T Cell
T-Cell
T-Lymphocytes
thymus derived lymphocyte
T Cells
T-Cells
A thymocyte-derived lymphocyte of immunological importance that is long-lived (months to years) and is responsible for cell-mediated immunity. T lymphocyte cells form rosettes with sheep erythrocytes and, in the presence of transforming agents (mitogens), differentiate and divide. These cells have the characteristic T3 surface marker and may be further divided into subsets according to function, such as helper, cytotoxic, etc.
T lymphocyte
Seminiferous Tubules
Seminiferous Tubule
Central DNA Flap Sequence
In Lentivirus, a central strand displacement event consecutive to central initiation and termination of plus strand synthesis creates a plus strand overlap: the central DNA flap. This feature promotes efficient nuclear import and viral replication in non-dividing cells. (from Cell 2000;101:173-85)
The anterior portion of the head extending from the forehead to the chin and ear to ear. The facial structures contain the eyes, nose and mouth, cheeks and jaws.
Facial
Face
1: 153641739-153623738
Physical location of INSRR_Gene
Cauda Equina
The portion of the intestinal covering that contracts causing peristalsis. It surrounds the weblike submucosa of the distal portion of the digestive tract from the small intestine to the anus.
Large Intestinal Muscular Coat
Peritoneum
The tissue that lines the wall of the abdominal cavity, intestine, and mesentery. It consists of the parietal peritoneum that covers the inside of the abdominal wall and the visceral peritoneum that covers the surface of the intestine and mesentery.
Thick Filament
A myofilament composed of myosin.
16: 57325641-57298538
Physical location of GOT2_Gene
3q21-q24
A chromosome band present on 3q
The wall that separates the left and right ventricles of the heart.
Interventricular Septum
3: 133518957-133560302
Physical location of ACPP_Gene
Circular Ligament of the Tooth
White Blood Cell
White Blood Cells
WBC - White blood cell
white blood corpuscle
WBC
Leukocyte
Marrow leukocyte
White Cell
Reticuloendothelial System, Leukocytes
Leukocytes
Blood cells that are devoid of hemoglobin, capable of ameboid motion and phagocytosis, and act as the principal components of the immune system.
Blood leukocyte
4q25-q27
A chromosome band present on 4q
Transversus Thoracis
Inner Hair Cell
Hair Cells, Inner
Bulbous cells that are medially placed in one row in the organ of Corti. In contrast to the outer hair cells, the inner hair cells are fewer in number, have fewer sensory hairs, and are less differentiated. (MeSH)
Type I Hair Cell
Median Basilic Vein
Physical location of GPR54_Gene
19: 868503-872001
The distal portion of the upper extremity. It consists of the carpus, metacarpus, and digits.
Hand
Jugular Foramen
Posterior Lacerate Foramen
A follicle believed to be formed by degeneration of suppressed chief cells. Secretion of hormonal and/or other substances into intercellular spaces progressively forms follicular cavities.
Parathyroid Gland Follicle
A chromosome band present on 3q
3q21-q25
The membrane of the postsynaptic cell that is enriched with neurotransmitter receptors.
Postsynaptic Membrane
Subcutis
Subcutaneous Tissue
Subcutaneous Adipose Tissue
Adipose tissue located under the dermis. It binds underlying structures with the skin. The subcutis is important in the regulation of temperature of the skin itself and the body. The size of this layer varies throughout the body and from person to person.
Fertilized Egg
Ovum, Fertilized
Fertilized Ovums
Egg, Fertilized
Zygote
The cell formed by the union of two gametes, especially a fertilized ovum before cleavage. (Online Medical Dictionary)
13q13.3
A chromosome band present on 13q
7q35-q36
A chromosome band present on 7q
Nerve structures through which impulses are conducted from a peripheral part toward a nerve center. (MeSH)
Afferent Pathways
Afferent Pathway
Direct Cerebellar Tract
20q13.1-q13.2
A chromosome band present on 20q
Postcentral Gyrus
nodular parenchyma
Nodular Parenchymal Tissue
Normal tissue characterized by the presence of well defined parenchymal nodules.
A chromosome band present on 12q
12q24
A canal in the petrous region of the temporal bone that serves as the passage for cranial nerves (mainly the VII and VIII cranial nerves) towards the middle and inner ear.
Internal Auditory Canal
Lower Lobe of Kidney
Lower Lobe of the Kidney
KIDNEY, LOWER LOBE
Kidney Lower Lobe
The lobe of the kidney located in the lowest region of the kidney.
Lateral Wall of the Bladder
Lateral Wall of Bladder
Physical location of MADH3_Gene
15: 65145331-65270904
The protective covering surrounding the axon of neurons in the peripheral nervous system.
Peripheral Nerve Sheath
20q13.33
A chromosome band present on 20q
Reserve Stem Cell
Corpora Albicantia
STOOL
Gastrointestinal Tract, Feces
Feces
The material discharged from the bowel during defecation. It consists of undigested food, intestinal mucus, epithelial cells, and bacteria.
A chromosome band present on Xq
Xq26-q28
Laryngeal Ventricle
2: 27213585-27220914
Physical location of EMILIN_Gene
Posterior Pole of the Lens
Olfactory Supporting Cell
A cell that serves to provide support and protection to the olfactory epithelium.
Digital Ray
Salpingopharyngeus
20q13.32
A chromosome band present on 20q.
The concave side of the lymph node.
Lymph Node Hilum
Posterior Ulnar Vein
Descending Spinal Cord Tract
Descending Spinal Tracts
Descending Spinal Cord Tracts
Auricular Hillock
Facial Vein
Physical location of GA_Gene
12: 55168448-55151004
Late Endosome
A multivesicular body that can fuse with the lysosome to target extracellular factors for degradation.
The hemispheric projection, including the mammary gland, located on the anterior portion of the chest, lateral to the midline, on the side of the body to the east when facing north.
Right Breast
3: 167037952-166973395
Physical location of BCHE_Gene
The fallopian tubes, ovaries, and supporting ligaments of the uterus. (MeSH)
Uterine Adnexa
Appendage of the Uterus
17q23-q24
A chromosome band present on 17q
A conical thyroid gland lobe. When it is present, it usually arises from the isthmus.
Pyramidal Lobe
Pyramidal Lobe of the Thyroid
Disulfide Linkage
A disulfide linkage is a covalent bond between 2 sulfide atoms from the thiol group of 2 cysteine residues (S-S). They occur both interstrand and intrastrand.
Disulfide Bond
8q24.12
A chromosome band present on 8q
3q21-q28
A chromosome band present on 3q
Lower Opening of the Thorax
Lateral Ligament of the Liver
Lateral Ligament
11: 117720311-117729261
Physical location of CD3G_Gene
Active Site
The catalytic site of an enzyme, the part of an enzyme where the actual enzymatic function is performed.
17q23-q25
A chromosome band present on 17q
22: 28967302-28960997
Physical location of LIF_Gene
Cells derived from primitive cell types in the neural crest. During ontogeny they migrate to the foregut and specific locations of the neuroendocrine system. Properly located these cells form part of the normal hormone producing tissues of the neuroendocrine system. If misdirected these cells may become hyperplastic, adenomatous, or malignant. (MeSH)
APUD Cell
APUD Cells
Lanugo
Fine downy hair that covers the body of a human fetus beginning in the fifth month of gestation; it is usually shed by the ninth month of gestation.
Disc
Disk
Any body structure resembling a flat circular plate.
Mandibular Prominence
Physical location of IRAK2_Gene
3: 10181630-10255723
Dbl Homology Domain
RhoGEF Domain
DH Domain
The Dbl homology (DH) or RhoGEF domain consists of a 150 amino acid region that induces Rho family GTPases to displace GDP. This effectively activates the Rho GTPase by allowing binding to GTP, which is in excess over GDP in the cell. The DH domain is invariably proceeded by a pleckstrin homology (PH) domain. While not absolutely required for catalysis of nucleotide exchange, the PH domain appears to greatly increase catalytic efficiency in many cases. Rho proteins control actin dynamics, gene expression, membrane trafficking, growth factor signaling, and cellular transformation. Proteins encoding DH domains (RhoGEFs) also play a role in these events as they function as the primary activators of Rho GTPases. In fact, many RhoGEFs were identified based on their transforming activity, which was abrogated upon disruption of their DH domain. (Pawson Lab, SLRI, Mount Sinai Hospital, 2003)
MUSCLE, GASTROCNEMIUS
A large muscle in the back of the lower leg. Its action involves the plantar flexion of the foot.
Gastrocnemius Muscle
Anterior Wall of Nasopharynx
The anterior aspect of the nasopharynx.
Anterior Wall of the Nasopharynx
Pupil
Xq28
A chromosome band present on Xq
One of the two bundles of nerve fibers (dorsal and ventral roots) emerging from the spinal cord that join to form each spinal nerve.
Nerve Root
The part of the skeleton that includes the bones of the upper and lower limbs.
Appendicular Skeleton
Middle Cerebral Artery Branch
A chromosome band present on Xq
Xq27
Within most types of eukaryotic CELL NUCLEUS, a distinct region, not delimited by a membrane, in which some species of rRNA (RNA, RIBOSOMAL) are synthesized and assembled into ribonucleoprotein subunits of ribosomes. In the nucleolus rRNA is transcribed from a nucleolar organizer, i.e., a group of tandemly repeated chromosomal genes which encode rRNA and which are transcribed by RNA polymerase I.
Nucleolus
The bony anterior part of the roof of the mouth separating the nose from the mouth.
Hard Palate
PALATE, HARD
Chromosome 11 Physical Location
Glucagon Secreting Cell
Glucagon Cell
Alpha Cell
A cell in the periphery of the pancreatic islets that secretes glucagon.
Nucleotide sequences present in multiple copies in the genome. There are several types of repeated sequences. Interspersed (or dispersed) DNA repeats (Interspersed Repetitive Sequences) are copies of transposable elements interspersed throughout the genome. Flanking (or terminal) repeats (Terminal Repeat Sequences) are sequences that are repeated on both ends of a sequence, for example, the long terminal repeats (LTRs) on retroviruses. Direct terminal repeats are in the same direction and inverted terminal repeats are opposite to each other in direction. Tandem repeats (Tandem Repeat Sequences) are repeated copies which lie adjacent to each other. These can also be direct or inverted. The ribosomal RNA and transfer RNA genes belong to the class of middle repetitive DNA.
Repetitive Sequence
Repetitive Element
Eye Segment
Segment of the Eye
A medium-sized round lymphocyte of B or T-cell lineage with prominent nucleoli. It is an intermediate cell between the lymphoblast and the small, mature lymphocyte.
Prolymphocyte
A chromosome band present on 12q
12q21
A light and spongy bone that is cubical in shape. This bone is positioned at the anterior part of the cranium, sitting between the two orbits, at the roof of the nose. It consists of four parts: a horizontal or cribriform plate; a perpendicular plate; and two lateral masses or labyrinths.
Ethmoid Bone
Lateral Orbitofrontal Artery
An irregularly shaped bone positioned at the back part of the nasal cavity between the maxilla and the pterygoid process of the sphenoid. It forms the posterior part of the hard palate and the lateral wall of the nasal fossa and helps to form the floor of the orbit as well as several adjoining parts.
Palatine Bone
A chromosome band present on Xq
Xq26
1: 148822584-148818055
Physical location of S100A11_Gene
Physical location of HSD17B7_Gene
1: 159492238-159514266
Around 70 amino acids and weakly conserved, the PWWP Domain is named after a conserved Pro-Trp-Trp-Pro motif often found as multiple copies in proteins that contain chromatin-association domains or in cell growth and differentiation transcription factors, such as WHSC1 (C-terminus) and ASH1/Trithorax Group proteins. Although its function is unknown, the amino acid composition suggests that it may be involved in protein-protein interactions. The domain N-terminal half resembles a barrel-like five-stranded structure; the C-terminal half contains a five-helix bundle. The halves form a module that exhibits positive electrostatic potential. Alone, the domain binds DNA in vitro, probably through its basic surface. (NCI)
PWWP Domain
A chromosome band present on 12q
12q22
Seromucous Salivary Gland
Physical location of CDKN3_Gene
14: 53933476-53956682
The long bone of the forearm that extends from the lateral aspect of the elbow to the thumb-side of the wrist.
RADIUS
BONE, RADIUS
Radial Bone
Radius Bone
The space between the presynaptic terminal and the postsynaptic membrane.
Synaptic Cleft
Globular Actin
The monomeric form of actin.
G-actin
Xq25
A chromosome band present on Xq
A chromosome band present on 4q
4q11-q13
Angioblastic Cord
Endothelial cord in the cardiogenic mesoderm of the embryo that appears in the third week of gestation. It gives rise to the embryonic heart.
A bone marrow stem cell with variable lineage potential is an undifferentiated cell which can undergo division and give rise to a variety of hematopoietic cells.
Bone Marrow Stem Cell with Variable Lineage Potential
Physical location of CRSP8_Gene
9: 131984807-131765053
Physical location of GNAZ_Gene
22: 21737223-21791778
Brain Nucleus
Renal Calyx
Renal Calix
Renal Calyces
Physical location of HNRPAB_Gene
5: 177564147-177570788
Knee Skin
12q23
A chromosome band present on 12q
A chromosome band present on Xq
Xq24
4q11-q12
A chromosome band present on 4q
A structure of special sense serving as an organ of the sense of smell and as an entrance to the respiratory tract.
Nose
A cluster of highly aggregated chromatin.
Karyosome
Neural Stem Cell
Neural Stem Cells
A stem cell derived from embryonic sources or found in adult neural tissue. It has the capacity to generate all the multiple cell types found in the brain and spinal cord.
The opening in the diaphragm that allows for passage of the descending aorta.
Aortic Opening
A chromosome band present on 16p
16p11.2
8p21
A chromosome band present on 8p
Eye
Ophthalmic
Optic
Eyeball
Ocular
The organ of sight or vision.
Aortic Arch Branch
An artery originating from the aortic arch.
Threonine Phosphorylation Site
It refers to amino acid threonine residue that was covalently modified by phosphate group (PO4-). (NCI)
Cis-acting locus is a section of DNA that affects the activity of DNA sequences on that same molecule of DNA.
Cis-Acting Locus
Cis-Acting Sequence
5' Untranslated Region
Sequences on the 5' end of messenger RNAs that are not translated into protein. 5'UTR extends from the transcription start site to just before the ATG translation initiation codon. This region contains the ribosome binding site and other transcription and translation regulating sequences.
Crystalline Inclusion
A detectable aggregation of small molecules in the cytoplasm.
Oval Foramen
Physical location of CCL14_Gene
17: 31337852-31334805
4q13.3
A chromosome band present on 4q
Chromosome 8p22
A chromosome band present on 8p
8p22
5q12.3
A chromosome band present on 5q
1: 163921801-164117000
Physical location of POU2F1_Gene
Choroid Plexus Epithelium of the Lateral Ventricle
Basal Domain of the Epithelium
Lateral-Occipital Sulcus
A lymph node located in proximity to any of the scalene muscles.
Scalene Lymph Node
Proteasome
Proteolytic complexes, proteolytic core of the proteasome system, that degrade cytosolic and nuclear proteins are implicated in ATP dependent ubiquitin protein complex degradation and in antigen processing in antigen presenting cells. The 20S proteasome (700 kD), essential in ATP ubiquitin degradation pathway, has 13-15 subunits each of which has three or four different peptidase activities. The 20S proteasome interacts with additional subunits, PA700 and PA28, to form an ATP-dependent multicatalytic proteinase complex (MPC) involved in the degradation of ubiquitinated cellular proteins and certain non-ubiquitinated proteins. 26S proteasomes may be formed in an ATP dependent fashion from a 20S proteasome and additional components, CF1 (660 kD), CF2 (250 kD) and CF3 (600 kD).
Proteosome
22: 22708785-22700695
Physical location of GSTT1_Gene
Sphenoid Bone
An anatomic site targeted for a particular medical intervention.
Target Anatomic Site
Targeted Anatomic Site
Inferior Thyroid Artery
A lymph node located along the external iliac artery.
External Iliac Lymph Node
Tissue composed of tubuloalveolar glands embedded in fibromuscular stroma. The stroma is smooth muscle separated by strands of connective tissue rich in collagenous and elastic fibers. The secretory alveoli of the prostate are irregularly shaped with papillary projections of the mucosa into the lumen of the gland.
Prostatic Tissue
GLAND, PROSTATE
Prostatic Parenchyma
A chromosome band present on 9q
9q33-q34.1
A chromosome band present on 8q
8q13.1
The POU domain is a bipartite DNA binding domain recognized originally as a shared structural motif in the Pit-1, Oct-1/Oct-2, and Unc-86 transcription factors (POU). It is comprised by a C-terminal homeo domain, and an N-terminal POU-specific domain, separated by a non-conserved linker. The POU-specific domain, like the homeo domain, is folded in a helix-turn-helix motif.
POU Domain
Adrenal Gland Capsule
The thin fibrous tissue that surrounds the adrenal gland.
A chromosome band present on 7q
7q21-q22.1
Left Inguinal Region
Left Iliac Region
Macula of Utricle
Physical location of EPHA8_Gene
1: 22635323-22675393
Lamellar Bone
A type of bone tissue. There are two subtypes of mature bone - compact and spongy. Compact bone is very dense and hard on the outside. Compact bone forms the thick-walled tube of the shaft of long bones and covers the epiphyses of long bones. Spongy bone is lightweight and consists of trabeculae, which branch and intersect to form a sponge like network, and red bone marrow for hematopoiesis. Short bones and the epiphyses of long bones consist mainly of spongy bone.
Mature Bone
Cloacal Membrane
Vaginal Fornix
Temporary Tooth
Any of the teeth of the first dentition, which are usually shed and replaced by the permanent teeth.
Primary Tooth
Deciduous Tooth
Physical location of ABL2_Gene
1: 175930393-175808414
Extensor Carpi Radialis Brevis
Sublingual Lymph Node
A lymph node located under the tongue in the floor of the mouth.
LYMPH NODE, SUBLINGUAL
The anterior side of the thorax from the neck to the abdomen. The shape of the chest is often regarded as potential insight into a disease process, as in the case of barrel chest and respiratory dysfunction.
Chest
SPINAL CORD, THORACOLUMBAR
Thoracolumbar Region
The region of the spinal cord pertaining to the thoracic and lumbar vertebrae.
Physical location of BCAR3_Gene
1: 93859223-93739372
19: 49943871-49955140
Physical location of BCL3_Gene
Nail Plate
A chromosome band present on 9p
9p12
Chromosome 18 Physical Location
1: 89069241-89030638
Physical location of GTF2B_Gene
Sinus, Maxillary
Antrum of Highmore
Apertura Sinus Maxillaris
Antrum of Highmori
A pyramidal-shaped, thin-walled, air-filled cavity located in the maxilla. It is lined by mucus membrane and periosteum (mucoperiosteum) which contains cilia. It is adjacent to the nasal cavity and communicates with the middle meatus of the nose. It is the largest paranasal sinus and is composed of three recesses: alveolar, zygomatic, and infraorbital.
Antrum Highmori
Antrum, Maxillary
Maxillary Sinus
Nerve fibers which project from the central nervous system to autonomic ganglia. In the sympathetic division most preganglionic fibers originate with neurons in the intermediolateral column of the spinal cord, exit via ventral roots from upper thoracic through lower lumbar segments, and project to the paravertebral ganglia; there they either terminate in synapses or continue through the splanchnic nerves to the prevertebral ganglia. In the parasympathetic division the fibers originate in neurons of the brain stem and sacral spinal cord. In both divisions the principal transmitter is acetylcholine but peptide cotransmitters may also be released. (MeSH)
Preganglionic Autonomic Fiber
preganglionic fiber
Autonomic Fibers, Preganglionic
Internal Abdominal Ring
Retromandibular Vein
Temporo-Maxillary Vein
Pituicyte
A cell of the neural lobe of the hypophysis. It has long branching processes and resembles neuroglia. It secretes antidiuretic hormone.
URINARY BLADDER
Bladder
Urinary System, Bladder
Bladder Tissue
The tissue that forms the bladder wall. It consists of mucosa, muscular coat, and serosal surface.
15: 47502751-47566815
Physical location of FGF7_Gene
Callosomarginal Artery
10q11-q12
A chromosome band present on 10q
Esophagus Secretion
Bone Marrow Stem Cell with Potential to Differentiate to Granulocytic Lineage
A primitive, undifferentiated blood cell which can undergo division and give rise to white blood cells in the neutrophil, eosinophil or basophil lines.
A chromosome band present on 4q
4q32.2
6: 69404158-7056120
Physical location of BAI3_Gene
Superior Mesenteric Artery
Popliteal Artery
4: 89436901-893700019
Physical location of ABCG2_Gene
Superior Vesical Artery
5: 158690059-158674369
Physical location of IL12B_Gene
Lower Third of the Esophagus
The lower one third of the esophagus in which the muscle layer is composed of muscle cells predominantly of the smooth type.
ESOPHAGUS, LOWER THIRD
Lower Third of Esophagus
A chromosome band present on 12q
12q23.1
Lower-inner Quadrant of Breast
Lower-Inner Quadrant of the Breast
The quarter of the breast which is inferior and medial.
A small spherical body composed of keratinized squamous epithelial cells arranged in a concentric pattern in the medullary portion of the thymus.
Thymic Corpuscle
Hassall's Body
Virchow-Hassall Body
Hassall's Concentric Corpuscle
Hassall's Corpuscle
Musculus Pectoralis Major
Pectoralis Major
A synapse between dendrites of two neurons.
Dendrodendritic Synapse
Foveolar Cell
An epithelial cell found in the glands of the gastric mucosa.
Internal Cuneiform Bone of the Foot
Omotransverse
The bone surface in a joint.
Articular Bone Surface
Gastric Tissue
The tissue of the stomach. It is composed of a fibrous outer layer bounded by smooth muscle, the submucosa, and the mucosa. The mucosa of the stomach consists of secretory cells that produce hydrochloric acid and gastric enzymes.
STOMACH
Physical location of BLK_Gene
8: 11388930-11459517
Innominate Vein
Flexor Hallucis Longus
Posterior Tibial Artery Branch
Mesencephalon
BRAIN, MIDBRAIN
Mid-brain
MIDBRAIN
The uppermost portion of the brainstem located between the pons and the diencephalon. The midbrain contains the cerebral peduncles, oculomotor, trochlear and red nuclei, substantia nigra and various other nuclei and tracts.
Gallbladder Serosal Surface
The inner lining of the lips.
Labial Mucosa
Cleidobrachial
The neural or post-neural lobe of the pituitary gland which stores and releases vasopressin, oxytocin, and neurophysins.
Posterior Lobe of Pituitary Gland
Posterior Pituitary Gland
Neurohypophysis
Posterior Lobe of Pituitary
Posterior Lobe of the Pituitary Gland
Inferior Parietal Convolution
Cytotrophoblast
6: 167383227-167424477
Physical location of FGFR1OP_Gene
The physical location of a gene feature expressed as chromosome and start and end base positions.
Gene Feature Physical Location
Coding Region
The sequences on a gene or messenger RNA that are translated into protein.
Protein Coding Sequence
Coding Feature
Coding Sequence
Protein Coding Region
10: 126839019-126667391
Physical location of CTBP2_Gene
Oocytes
The female gamete, germ cells in stages between the prophase of the first maturation division and the completion of the second maturation division.
Ovocytes
Egg, Unfertilized
egg/ovum
Egg
Oocyte
Ovum
Physical location of DLG1_Gene
3: 198513757-198259733
A structure found in the nucleus of human cells that is comprised of a strand of linearized double-stranded DNA plus proteins that package the DNA in a condensed coil form and regulate chromosomal function.
Human Chromosome
A chromosome band present on Yp
Yp11.2
Ductus Arteriosus
Axillary Artery
Olfactory System
17p12-17p11.2
A chromosome band present on 17p
BRAIN, SUBSTANTIA NIGRA
A large cell mass extending forward, over the dorsal surface of the crus cerebri, from the rostral border of the pons into the subthalamic region. It is composed of a dorsal stratum of closely spaced pigmented cells, the pars compacta, and a larger ventral region of widely scattered cells, the pars reticulata. The pars compacta includes numerous cells that project forward to the striatum (caudate nucleus and putamen) and contain dopamine, which acts as the primary neurotransmitter at the synaptic endings. Other, apparently non-dopaminergic cells project to portions of the ventral nucleus of thalamus, the superior colliculus and reticular formation. The nigrostriatal projection is reciprocated by a striatonigral fiber system with multiple neurotransmitters, chief among which is gamma-aminobutyric acid (GABA). The substantia nigra is involved in the metabolic disturbances associated with Parkinson's disease and Huntington's disease.
Substantia Nigra
Follicular Ovarian Cell
A cell located in the epithelium of the ovarian follicles.
Lower Lobe of Left Lung-LLL
Lower Lobe of the Left Lung-LLL
LUNG, LEFT LOWER LOBE
Inferior Lobe of the Left Lung
Lung Left Lower Lobe
The larger lobe of the left lung, situated below and behind the oblique fissure.
Lower Lobe of the Left Lung
Any of the muscles of the abdomen that comprise the abdominal wall; these muscles include the rectus abdominis, the external and internal oblique muscles, the transversus abdominis, and the quadratus abdominis.
Abdominal Muscle
The tissues that surround the organs that are present within the abdominal cavity. The abdominal wall tissue is composed of layers of fat, parietal peritoneum, fascia, and muscles.
Abdominal Wall
A chromosome band present on 7p
7p15-p14
A system of neurosecretory neurons that release hormones to the circulatory system.
Neuroendocrine
Neurosecretory System
Neuroendocrine System
Branch
A part of a forking structure; a division or offshoot from a main stem.
19p13.1-p13.2
A chromosome band present on 19p
Cerebral Gyrus
A chromosome band present on 17q
17q12-q21.1
19q13.41
A chromosome band present on 19q
Ovaries
Genital System, Female, Ovary
One of the paired female reproductive glands containing the ova or germ cells; the ovary's stroma is a vascular connective tissue containing numbers of ovarian follicles enclosing the ova.
Ovary
Foot Plate
Yp11.3
A chromosome band present on Yp
Medial Golgi
A network of membrane components where both post-translational modification and sorting of proteins takes place.
Refractile Media
Dioptric Media
Splenic Cord
1q42-q43
A chromosome band present on 1q
Superior Suprarenal Artery
7p15-p13
A chromosome band present on 7p
Temporal Fossa
Physical location of IL15_Gene
4: 142915359-143012217
A chromosome band present on 19q
19q13.42
A lipid bilayer that encloses a lysosome.
Membrane of the Lysosome
Chromosome 8 Physical Location
14: 20222609-20232185
Physical location of ANG_Gene
Middle Ear
The part of the ear including the eardrum and ossicles. The middle ear leads to the inner ear.
12p13.2
A chromosome band present on 12p
External Lower Lip
LIP, LOWER
The external surface of the lower lip.
Aborted Fetus
Products of conception expelled or removed upon miscarriage or termination of a pregnancy.
Abortus
Physical location of FRAT1_Gene
10: 99069012-99071665
16: 27468775-27379570
Physical location of GTF3C1_Gene
A chromosome band present on 5p
5p13
Physical location of USF2_Gene
19: 40451736-40462558
Brachial Plexus
A nerve network originating from C5 to T1 that supplies cutaneous and muscular innervation to the arm and hand.
NERVE, BRACHIAL
Neural Fold
Pulmonary Neuroendocrine Cell
12p13.3
A chromosome band present on 12p
1: 26032413-26047074
Physical location of EXTL1_Gene
External Plantar Artery
Squamous Epithelium
A simple or stratified flat epithelium.
Physical location of DRD2_Gene
11: 112851091-112785527
The inactive, condensed X chromosome in a female somatic cell.
Barr Body
Abdominal Aorta
The portion of the descending aorta that lies within the abdomen, beginning below the diaphragm and ending at its division into the right and left common iliac arteries.
A specialized tactile sensory nerve ending in the epidermis, characterized by a terminal cuplike expansion of an intraepidermal axon in contact with the base of a single modified keratinocyte. SYN meniscus tactus, Merkel's corpuscle, Merkel's tactile cell, Merkel's tactile disk, tactile disk.
Merkel's Tactile Cell
Tactile Meniscus
Meniscus Tactus
Tactile Disk
Merkel's Corpuscle
Hypoxia-Responsive Elements
DNA sequences in a gene's promoter region that mediate expression during hypoxia. Since unlike normal tissues, solid tumors frequently have regions of hypoxia, suicide genes controlled by hypoxia-responsive elements may provide a means for cancer-specific gene therapy.
The fourth layer of the cerebral cortex, composed of many densely packed granule cells with short axons and some small pyramidal cells, and traversed by a stria of horizontally arranged fibers. It contains neurites derived from cells of other layers and areas of the cerebral cortex and subcortical areas.
Inner Granular Layer of the Cerebral Cortex
Internal Granular Layer of the Cerebral Cortex
A chromosome band present on 6q
6q21-q22
Aryteno-Epiglottic Fold
A membranous fold extending between the arytenoid cartilage and the epiglottis.
Physical location of CCL21_Gene
9: 34700147-34699002
A chromosome band present on 5q
5q11-q12
Chromosome 7 Physical Location
Plasmacytoid Dendritic Cell Precursor
A cell found in peripheral blood, lymphoid tissue, and some inflamed tissue. It produces vast amounts of type I interferons especially in response to viruses, therefore playing an important role in antiviral immunity and triggers for adaptive immune responses.
The fourth lumbar vertebra counting from the top down.
L4 Vertebra
The upper leg bone positioned between the pelvis and the knee.
Femur
Femoral
BONE, FEMUR
Bone, Femoral
Plasma Cell
Blood Plasma Cell
Plasmacytes
plasmacyte
Plasmocyte
Plasma Cells
plasmacytic
4: 188020126-187884098
Physical location of FAT_Gene
Physical location of CCL13_Gene
17: 29707584-29709742
A chromosome band present on 5q
5q12.2
Posterior Carpal Artery
Physical location of EIF2B4_Gene
2: 27504851-27498881
Lower Lip
The lip that covers the anterior portion of the mandible.
4q28-q31
A chromosome band present on 4q
Beta-Catenin-Like Repeat
ARM Domain
Beta-Catenin-Binding Domain
Armadillo/Beta-Catenin-Like Repeat
Beta-Catenin Binding Repeat
Armadillo Repeat
Identified in over 240 functionally diverse proteins from yeast to man, ARM Repeats are approximately 40-amino acids long and composed of two longer anti-parallel helices (H2 and H3) that follow a perpendicular short helix (H1). Tandem repeats form a right-handed superhelix (3 helixes per unit); tight repeat packing creates a cylindrical hydrophobic core throughout the structure. Lined by highly conserved residues, the positively charged groove of the superhelix appears to mediate interaction with acidic surfaces of target proteins. Despite amino acid variability, ARM repeat structures are highly conserved. Though involved in protein-protein interactions, no common features among target proteins have been identified. ARM repeats have a common phylogenetic origin with the HEAT repeat; both contain seven highly conserved hydrophobic residues.
6: 52159144-52163395
Physical location of IL17_Gene
It refers to amino acid residue within a peptide that accepts covalent linkage of fatty acid, myristoyl group (C13H27-) as one of the co-translational modifications. N-myristoylation, catalyzed by N-myristoyltransferase, is the amide modification of proteins by the addition of a myristoyl group to an N-terminal glycine residue. (NCI)
Myristoylation Site
Myristic Acylation Site
Physical location of DDR1_Gene
6: 30959840-30975912
2q12
A chromosome band present on 2q
A chromosome band present on 1q
1q31-q32
Occipital Artery
Musculoskeletal System Part
A chromosome band present on 1p
1p31.3
Left Subcostal Vein
A chromosome band present on 4q
4q28-q32
The dorsal part of the cloacal membrane following its partition by the urorectal septum.
Anal Membrane
Physical location of IRS2_Gene
13: 109236915-109204187
Neuron, Neuroepithelial Cell, and Supporting Cell of the Nervous System
A grouping for all the different types of cells of the nervous system.
Neural Cell, Neuroepithelial Cell, and Supporting Cell of the Nervous System
Nerve Cell, Neuroepithelial Cell, and Supporting Cell of the Nervous System
Premonocyte
Promonocyte
An immature cell of the mononuclear phagocytic system. It is the representation of one stage of monocyte development.
Bronchus Lamina Propria
Efferent Ductule Epithelium
Gamma/Delta T-Lymphocyte
A resting, mature T cell that probably plays a primary role in suppressor/cytotoxic phenomena.
4: 996082-1010516
Physical location of FGFRL1_Gene
Laryngeal Connective Tissue
Vacuolar
Vacuole
Any membrane-enclosed spaces or cavities within a cell.
BFU-E - Burst-form unit eryth
Progenitor Cells, Erythropoietic
Committed, erythroid stem cells derived from myeloid stem cells. The progenitor cells develop in two phases: erythroid burst-forming units (BFU-E) followed by erythroid colony-forming units (CFU-E). BFU-E differentiate into CFU-E on stimulation by erythropoietin, and then further differentiate into erythroblasts when stimulated by other factors. (MeSH)
BFU-E
Stem Cells, Erythroid
Erythroid Progenitor Cell
BFU-E - Burst-forming unit erythroid
Erythroid Progenitor Cells
Erythroid Precursor Cells
CFU-E
Erythropoietic Stem Cells
Burst-Forming Units, Erythroid
Erythroid Stem Cell
Colony-Forming Units, Erythroid
Obturator Nerve
A nerve that arises from the second, third, and fourth lumbar nerves and enters the thigh through the obturator canal. It is responsible for the sensory innervation of the skin of the medial aspect of the thigh and also responsible for the motor innervation of the adductor muscles of the lower extremity.
Pubic Bone
Pubis
Either of the two bones (left and right) that form the front of the pelvis.
Physical location of CRK_Gene
17: 1306294-1272199
Breast Tissue
GLAND, MAMMARY
Mammary Gland Parenchyma
Mammary Gland Tissue
The glandular tissue of the breast. In females, it is composed of numerous lobules with alveolar ducts and alveoli. In males, it is composed of rudimentary glands.
Gastrosplenic Omentum
The portion of the brain located at the base of the skull that is responsible for balance, equilibrium and movement.
Cerebellum
Cerebellar
Physical location of ATR_Gene
3: 143780349-143650778
Anterior Parietal Artery
The artery that delivers blood to the anterior portion of the parietal lobe.
Coccygeal Muscle
20: 56848190-56919642
Physical location of GNAS_Gene
Bronchial Tree
The left and right bronchi considered together with their branches.
YDYVHL Motif
YDYVHL (tyrosine-aspartic acid-tyrosine-valine-histidine-leucine) is a preferred substrate sequence by focal adhesion kinase. The phosphorylated YDYVHL containing protein recruits src family kinases, which can then phosphorylate other tyrosine residues within the peptide. (NCI)
YDYVHL Domain
Basophilic Granulocyte
Basophils
Basophilic Leukocyte
Blood Basophil
Marrow Basophil
Basophil
17: 35697672-35712539
Physical location of CDC6_Gene
Physical location of FGF20_Gene
8: 16904045-16894705
Bile Duct Tissue
DUCT, BILE
The tissue that forms the bile duct wall. It is lined by epithelium.
2q14
A chromosome band present on 2q
Interatrial Septum
The tissue that separates the right atrium from the left atrium in the heart.
The middle layer of the blood vessel wall. It consists of concentrically arranged smooth muscle and may include elastic tissue. Its thickness will depend on the type of vessel, thicker in arteries than in veins.
Tunica Media
Subscapularis
SITE, SURGICAL
The anatomic site of a cut made during surgery. The term may also refer to the resultant scar from the surgical procedure.
Incision Site
Cecal Diverticulum
Lentiform Nucleus
Nucleus Lenticularis
Lenticular Nucleus
Choroid Plexus of the Third Ventricle
Physical location of JUNB_Gene
19: 12763310-12765125
A chromosome band present on 4p
4p16.1
BRAIN, BASAL GANGLIA
Clusters of neurons comprising the globus pallidus, putamen, caudate, nucleus accumbens, substantia nigra and subthalamic nucleus. They are involved with high level aspects of inhibitory motor activity in coordination with the excitation commands issued from the cerebellum.
Basal Ganglia
The layer of areolar tissue situated beneath the mucous membrane in the distal portion of the digestive tract from the small intestine to the anus.
Large Intestinal Submucosa
Physical location of ECGF1_Gene
22: 49258599-49254325
15q15.3
A chromosome band present on 15q
Urorectal Septum
A chromosome band present on 19q
19q13.3-q13.4
A sequence of nucleotides in that contains no termination codons and so can potentially translate as a polypeptide chain.
Open Reading Frame
ORF
Scalenus Medius
6: 32929729-32920965
Physical location of TAP1_Gene
Thyroid Gland Capsule
Inner Rod of the Corti
Inner Rod of Corti
Muscular coat consisting of two layers of smooth muscle - an external, longitudinal, and an internal, circular layer. The longitudinal fibers are thinly scattered over the surface of the small intestine, and are more distinct along its free border. The circular fibers form a thick, uniform layer, and are composed of plain muscle cells of considerable length. The muscular coat is thicker at the upper than at the lower part of the small intestine. Interstitial cells of Cajal are present in the small intestinal muscular coat.
Small Intestinal Muscular Coat
Medullary Artery
A nerve that originates from the lumbar nerves and innervates the anterior region of the thigh.
Femoral Nerve
Chromosome 3 Physical Location
Aponeurosis
A flat, tendon-like membrane that serves to bind muscles or to attach muscles to bones.
Submental Vein
Occipital Horn of the Lateral Ventricle
A nerve cell with several processes, usually an axon and three or more dendrites.
Multipolar Neuron
Inner Segment of the Photoreceptor Cell
The peritoneal fold that covers and attaches the ovary to the broad ligament.
MESOVARIAN LIGAMENTS
Mesovarian Ligament
Mesovarium
A chromosome band present on 15q
15q15.2
Dorsal Hand Interosseous Muscle
21: 38878739-38675671
Physical location of ERG_Gene
12: 115781952-115761748
Physical location of HRK_Gene
SITE, BIOPSY
The anatomic site targeted for a biopsy procedure.
Biopsy Site
Gene Physical Location
The physical location of a gene expressed as chromosome and start and end base positions.
Hand Digit 3
Middle Finger
Ciliary Process
4p16.3
A chromosome band present on 4p
A chromosome band present on 7q
7q34-q35
Epithelial Microvillus
A cell with a centrally placed nucleus found in the proximal portion of pancreatic intercalated duct that protrudes into the acinus. It secretes bicarbonate made in the cell by the dissociation of carbonic acid in the presence of carbonic anhydrase II. These cells are thought to act as signal transducers, influencing the degranulation of the acinar cells.
Pancreatic Centroacinar Cell
Physical location of MMP11_Gene
22: 22439590-22451056
14q11.2-q12
A chromosome band present on 14q
Index Finger
Hand Digit 2
19: 16599754-16547838
Physical location of CRSP7_Gene
The cytoplasmic-facing layer of the plasma membrane.
Inner Leaflet of the Lipid Bilayer
Fossa of the Antihelix
Fossa Triangularis
Fossa of Antihelix
Macula of Saccule
A type of glial cell. Microglia are capable of phagocytosis and play an important role in a wide spectrum of neuropathologies. They have also been suggested to act in several other roles including in secretion (e.g., of cytokines and neural growth factors), in immunological processing (e.g., antigen presentation), and in central nervous system development and remodeling. (MeSH)
Microgliocyte
Gitter cell
Hortega cell
Microglia
microglial cell
perivascular glial cell
mesoglia
17: 15788956-15819935
Physical location of ADORA2B_Gene
High Endothelial Venule
The posterior projection from the body of a vertebra that encloses the vertebral foramen; it consists of paired pedicles and laminae; the spinous, transverse, and articular processes arise from the arch. In aggregate, the venous arches-and the ligamenta flava that unite them-form the posterior wall of the vertebral (spinal) canal.
Arch of the Vertebra
Cutaneous Muscle
Trachea Basal Lamina
Large Intestinal Wall Tissue
LARGE INTESTINE
Large Bowel
The tissue of the large intestine. It is composed of four layers - mucosa, submucosa, smooth muscle with inner circular and outer longitudinal layers, and serosa. The mucosa has a large number of goblet cells but does not have any villi. The longitudinal muscle layer is incomplete. The longitudinal muscle is limited to three distinct bands, called teniae coli that run the entire length of the colon. Contraction of the teniae coli exerts pressure on the wall and creates a series of pouches, called haustra, along the colon. Epiploic appendages, pieces of fat-filled connective tissue, are attached to the outer surface of the colon.
Centromedian Nucleus of the Thalamus
Physical location of IL12RB2_Gene
1: 67485068-67574604
Little Finger
Pinkie
Hand Digit 5
5: 156502453-156498017
Physical location of CRSP9_Gene
Pancreatic Lymph Node
A lymph node of the pancreas.
LYMPH NODE, PANCREATIC
Posterolateral Part of the Prostate
Postero-Lateral Part of the Prostate
The part of the prostate gland that is lateral and posterior.
Metatarsal Bone
Metatarsal Bones
A bone belonging to the middle part of the foot located between toes and ankle. There are 5 metatarsal bones and they are numbered from the medial side.
18: 43710924-43621616
Physical location of MADH2_Gene
Any part of an organism.
Body Part
Physical location of LOX_Gene
5: 121441853-121429918
Nerve sheath that is part of the myelinated segment of an axon. It is composed of Schwann cells.
Neurilemma
Sheath of Schwann
6: 146392112-146800427
Physical location of GRM1_Gene
Parasellar Cistern
Anterior Supratentorial Cistern
One of the supratentorial cisterns. It is also called parasellar supratentorial cistern.
Physical location of ADORA1_Gene
1: 199791439-199868189
Growing End of Microtubule
Growing End of the Microtubule
Plus End of Microtubule
The end of a microtubule where tubulin polymerization occurs.
Plus End of the Microtubule
Ring Finger
Hand Digit 4
Any one of the rearmost molars on each side of the upper and lower jaw in humans.
Wisdom Tooth
Third Molar
7: 42036134-41776911
Physical location of GLI3_Gene
12: 107325559-107187814
Physical location of CMKLR1_Gene
Deep Lymphatic Vessel
A small, round cell found in the lower part of the epidermis of the taste bud. It differentiates into a new receptor cell and renewed about every 10 days.
Taste Bud Basal Cell
Breast, Female
The organ of milk secretion; one of two hemispheric projections of variable size situated in the subcutaneous layer over the pectoralis major muscle on either side of the chest of the mature female; it is rudimentary in the male.
Female Breast
The sinuses and those parts of the respiratory system above the trachea. It includes the nares, nasopharynx, oropharynx, larynx, vocal cords, glottis and upper trachea.
Upper Respiratory System
A thin outer layer or film covering something.
Coat
Coated
Coating
Layer
Physical location of GRB7_Gene
17: 35147744-35157063
Small Cardiac Vein
Skeletal Muscle Cell
Skeletal Muscle Tissue Cell
BH2 Domain
Found in proteins that regulate apoptosis, conserved a-helix BCL-2 Homology (BH1-4) Domains are critical to protein apoptotic function and the protein ability to interact/dimerize with other family members or regulatory proteins. BCL-2 family proteins dimerize among pro- and anti-apoptotic class family members. BCL-2 homodimerization appears to involve head-to-tail interaction of N-terminal BH4 resides with more distal BH1, BH2, and BH3 regions. BCL-2/BAX heterodimerization appears to involve tail-to-tail interaction of the BCL-2 BH1, BH2, and BH3 regions and the BAX BH3 domain region. BCL-2 may suppress cell death partly by binding to BAX via the BH3 domain preventing BAX homodimer formation. (NCI)
BCL-2 Homology 2 Domain
Bcl-2 Homology Domain
Proteins that are related to bcl-2 are characterized by the presence of one or more highly conserved stretches of homology with bcl-2, designated BH1, BH2, BH3, BH4. These domains control the ability of these proteins to homo- and heterodimerize with other proteins. Competitive dimerization between family members is thought to regulate their function as regulators of apoptosis.
The body excluding the head and neck and limbs.
Trunk
Axillary Artery Branch
A chromosome band present on 7p
7p13-p12
Small Intestinal Crypt of Lieberkuhn
The area of the body exposed to radiation during radiation therapy.
Radiation Field
treatment field
Epithelium consisting of multiple layers of cells in which the top layer of cells are taller than they are wide. This epithelium is found in salivary gland ducts.
Stratified Columnar Epithelium
A level of DNA packaging in chromatin above that of the nucleosome, the fundamental subunit of chromatin structure. The chromatin fiber has a thickness of about 30 nanometers and results from the folding of a linear array of nucleosomes (thickness about 10 nm) into a more compact fiber.
Chromatin Fibril
30 nm Fiber
30 nm Chromatin Fiber
Chromatin Fiber
C6 Vertebra
The sixth of the seven cervical vertebrae.
Cerebellum White Matter
A chromosome band present on 12q
12q14
12q15
A chromosome band present on 12q
Gallbladder Lamina Propria
Synovial Bursa
Immunoglobulin genes are formed by somatic recombination of multiple gene elements. Light chains use variable (V) and joining (J) elements, whereas heavy chains incorporate an additional diversity (D) element between the V and J elements.
Immunoglobulin Diversity Region
A chromosome band present on 2p
2p25-p24
Cerebral White Matter
2pter-p12
A chromosome band present on 2p
BONE, PATELLA
A small flat triangular bone in front of the knee that articulates with the femur and protects the knee joint.
Patella
Sphenocavernous Region
Spinal Vestibular Nucleus
Radial Nerve
A large nerve that arises from the brachial plexus and enervates the extensor muscles and skin of the entire upper limb's posterior aspect.
NERVE, RADIAL
Nucleus of the Spinal Tract of the Trigeminal Nerve
21: 39099719-39118749
Physical location of ETS2_Gene
Physical location of GPRK5_Gene
10: 120957193-121205126
Inferior Frontal Convolution
Inferior Frontal Gyrus
Cricothyroid Ligament
7: 87150195-87183507
Physical location of ASK_Gene
12q12
A chromosome band present on 12q
A centrally placed component of the ventricular system of the brain located in the diencephalon. Cerebrospinal fluid from the lateral ventricles flows into the third ventricle via the foramina of Monroe and exits the third ventricle via the aqueduct of Sylvius. The thalamus and hypothalamus border the lateral walls of the third ventricle.
Third Ventricle
Third Ventricle of Brain
Ventricle, Third
Third Cerebral Ventricle
A synapse in which electrical connection is made directly through the cytoplasm, via gap junctions.
Electrical Synapse
Gingival Epithelium
A chromosome band present on 9p
9p13
Femoral Shaft
The cylindrical body of the femur.
Body of Femur
Xp22
A chromosome band present on Xp
Fissure of the Gallbladder
Thumb
The thick and short hand digit which is next to the index finger in humans.
Hand Digit 1
Xenograft
A graft transferred from a donor of one species to a recipient of another species.
PBL
Peripheral Blood Lymphocyte
Embryonic Artery
An organelle formed by the fusion of a phagosome with the lysosome, where the contents of the phagosome are degraded.
Phagolysosome
12q13
A chromosome band present on 12q
Prostatic Portion of the Male Urethra
URETHRA, PROSTATIC
Prostatic Urethra
That part of the male urethra that passes through the prostate gland.
Glossopharyngeal Nerve
Cranial Nerve IX
Nervus Glossopharyngeus
Ninth Cranial Nerve
Physical location of ACSL1_Gene
4: 186122364-186051899
19: 7718406-7710882
Physical location of CD209_Gene
Superior Frontal Sulcus
19: 14353266-14380535
Physical location of CD97_Gene
Orthochromatophilic Erythroblast
A cell derived from a polychromatophilic erythroblast in bone marrow. It has a dense nucleus and its cytoplasm is approaching the color of a mature erythrocyte. It differentiates into a reticulocyte when it extrudes its nucleus.
Supracardinal Vein
Ethmoidal Artery
A chromosome band present on 5q
5q31.3
Thymic Trabeculae
Thymic Trabecula
Lymph Node Sinus
An irregular tortuous space within lymph nodes through which a continuous stream of lymph passes entering into the efferent lymphatic vessels.
Lymphatic Sinus
Lymph Sinus
The tissue that generates and conducts electrical signals in the body. It contains the neurons.
Nerve Tissue
Nervous Tissue
NERVE
Mesorectum
The fold of peritoneum, or mesentery, attached to the upper portion of the rectum and connecting it with the sacrum.
The hydrophobic portion of the plasma membrane as seen during transmission electron microscopy because there is little to no binding of the detection reagent.
Electron-Lucent Plasma Membrane Layer
Spiral Organ of Corti
Organ of Corti
T4 Lymphocytes
CD4-positive T lymphocyte
CD4+ T-Lymphocyte
CD4-Positive Lymphocytes
CD4-Positive T-Lymphocytes
T4 Cells
CELLS.CD4
CD4+ T Lymphocytes
CD4-Positive T-Lymphocyte
CD4 lymphocytes
CD4+ T Lymphocyte
Anal Verge
The transitional zone between the moist, hairless, modified skin of the anal canal and the perianal skin.
Anal Margin
Physical location of FOXG1B_Gene
14: 28306038-28308622
A chromosome band present on 11p
11p12-p11.22
Small Intestinal Wall Tissue
The tissue of the small intestine. It comprises four layers - mucosa with simple columnar epithelium, submucosa, smooth muscle with inner circular and outer longitudinal layers, and serosa.
Duodenum/Jejunum/Ileum
SMALL INTESTINE
Small Bowel
Physical location of IL19_Gene
1: 203360610-203404720
A cluster of convoluted capillaries beginning at each nephric tubule in the kidney and held together by connective tissue.
Glomerular
Renal Glomerulus
Malpighian Tuft
Glomerulus
10q24-q25
A chromosome band present on 10q
Superior Maxillary Nerve
Syncytiotrophoblastic Cell
A large, multinucleated cell having hyperchromatic nuclei and abundant eosinophilic, sometimes vacuolated cytoplasm, in the outer syncytial layer of the trophoblast.
Caudate Lobe
Lobus Caudatus
Spigel Lobe
Couinaud Segment I
Spiegel's Lobe
Couinaud segment I, located on the posterior surface of the liver between the sulcus for the vena cava and the ligamentum venosum.
Ventroanterior Nucleus of the Thalamus
Cranial Nerve VIII
Eighth Cranial Nerve
Cranial Nerve Eight
VIIIth Cranial Nerve
Vestibulocochlear Nerve
The eighth cranial nerve composed of the acoustic nerve and the vestibular nerve. The nerve travels from the inner ear, enters the cranial cavity through the internal auditory foramen and joins the brainstem. The auditory nerve conveys impulses from the cochlea of the inner ear to the auditory nuclei of the brainstem. The vestibular nerve carries information from the labyrinths of the inner ear to the vestibular nuclei of the brainstem.
Fissure
A long narrow slit or groove that divides an organ into lobes.
5q31.1
A chromosome band present on 5q
A small canal that receives prostatic secretions from the glandular tubules and discharges it through the prostatic portion of the urethra.
Human Prostatic Duct
Prostatic Duct
11q14-q21
A chromosome band present on 11q
3p24.3
A chromosome band present on 3p
Triangular Ligament
Smegma
A white secretion of the sebaceous glands of the foreskin.
Embryonic Connective Tissue
Physical location of NOVA2_Gene
19: 51168497-51134631
4: 120600921-120596009
Physical location of FABP2_Gene
Nonmembranous Cytoplasmic Organelle
A functional area or structure in a cell that is not enclosed in a membrane.
A chromosome band present on 10q
10q24-q26
Alveus
The white myelinated fibers in the hippocampus adjacent to the wall of the lateral ventricle.
Medulla Spinalis
Spinal Cord
The elongated, approximately cylindrical part of the central nervous system of vertebrates that lies in the vertebral canal and from which the spinal nerves emerge.
MUSCLE TISSUE, PROXIMAL
A muscle located close to the trunk of the body.
Proximal Muscle
Connective and Soft Tissue Cell
A group of cells that includes fibroblasts, cartilage cells, adipocytes, smooth muscle cells, and bone cells. (MeSH)
Connective Tissue Cell
Connective Tissue Cells
Stereocilium
A non-motile microvillus-like structure found in certain epithelial tissues. It is comprised of plasma membrane that is supported by longitudinal actin filaments.
Stereovillus
Bladder Lamina Propria
Subiculum
Fossa of the Helix
Scapha
Fossa of Helix
Saliva
Head and Neck, Saliva
The watery fluid in the mouth made by the salivary glands. Saliva moistens food to help digestion and it helps protect the mouth against infections.
Physical location of IL6_Gene
7: 22540060-22544856
The bony cavity of the skull which contains the eye, anterior portion of the optic nerve, ocular muscles and ocular adnexa. Seven bones contribute to the structure of the orbit: the frontal, maxillary, zygomatic, sphenoid, lacrimal, ethmoid, and palatine bones.
BODY CAVITY, ORBITAL
Ocular Orbit
Orbital Cavity
Eye Socket
Orbit
Ascending Frontal Convolution
A convolution in the cerebral hemisphere between the central sulcus and the precentral sulcus.
20: 52120490-51993924
Physical location of BCAS1_Gene
Physical location of BIRC6_Gene
2: 32493965-32754622
Splenic Marginal Zone
Spleen Marginal Zone
A contractile cell found between the secretory cells and basement membrane of exocrine glands. Each myoepithelial cell has long cytoplasmic processes that wrap around a secretory unit. The contraction of the myoepithelial processes forces the secretory product from the secretory unit into its duct.
Myoepithelial Cell
Basket Cell
Extensor Digitorum Communis
One of numerous oval bodies found in the papillae of the skin, especially those of the fingers and toes; they consist of a connective tissue capsule in which the axon fibrils terminate around and between a pile of wedge-shaped epithelioid cells. SYN corpusculum tactus, oval corpuscle, touch corpuscle.
Meissner Corpuscle
Corpusculum Tactus
Tactile Corpuscle
Oval Corpuscle
Meissner's Corpuscle
Touch Corpuscle
Airway
The part of the respiratory system between the nose or mouth and the lungs.
NERVE, ULNAR
Ulnar Nerve
Azygos Articular Artery
Stroma
The non-neoplastic connective tissue of an organ.
Non-neoplastic Connective Tissue
Pancreatico-Duodenal Vein
A cell that develops from hematopoietic stem cells. An immature lymphocyte represents of one of five stages of lymphocyte maturation. It is estimated 90% of immature lymphocytes die in the thymus and bone marrow.
Immature Lymphocyte
Membrane of the Brain or Spinal Cord
The tissue that envelops the brain or spinal cord.
Other Body Fluids, Secretions
Liquid substances produced by living organisms to fulfill specific functions or excreted as waste. Secretions do not include hormones or enzymes.
Other Body Fluids and Secretions
2q36-q37
A chromosome band present on 2q
LYMPH NODE, SACRAL
Sacral Lymph Node
A lymph node located in the sacral region.
5q33.2-qter
A chromosome band present on 5q
Physical location of CCL26_Gene
7: 75046225-75043493
Cotyledon
Protein Turn
Turn
A protein secondary structure in which the polypeptide bends back on itself and is stabilized by hydrogen bonds.
Aciner Cells
Acinar Cell
A secreting cell that lines an acinus (i.e. a small sac or sac-like structure). A representative example is the acinar cell located in the pancreas that produces pancreatic enzymes and juices.
Thyroid Gland Follicular Cell
An epithelial cell lining the thyroid follicles.
Thyroid Follicular Cell
Intra-Thoracic Lymph Node
Intrathoracic Lymph Nodes
Any lymph node within the thoracic cavity.
Intrathoracic Lymph Node
A chromosome band present on 1q
1q21.3
A chromosome band present on 16p
16p12.1
Physical location of ADORA2A_Gene
22: 23153646-23162879
Infraorbital Artery
Microanatomy
Microscopic Anatomy
Microanatomic Structure
Those anatomic structures that are generally only visible through the use of microscopy.
A chromosome band present on 1p
1pter-p22.1
Cortical Cord
5: 68498669-68509826
Physical location of CCNB1_Gene
The layer of cells that line the lumen of an artery.
Artery Endothelium
Physical location of IL6ST_Gene
5: 55326520-55272452
A chromosome band present on 19p
19pter-q12
Epimysium
A nerve cell that employs dopamine as its neurotransmitter.
Dopaminergic Cell
Physical location of CXCL6_Gene
4: 75067448-75069512
Chemical Synapse Component
A functional part or structural element of a chemical synapse.
13: 27441317-27434279
Physical location of CDX2_Gene
Deep Epigastric Vein
Inferior Epigastric Vein
Dorsal Mesogastrium
ITAM
Immunoreceptor Tyrosine-Based Activation Motif
ARAM
Immunoreceptor Tyr-Based Activation Motif
Ag Recognition Activation Motif
ITAM (Immunoreceptor Tyrosine-based Activation Motif) or ARAM (Ag Recognition Activation Motif) (Y-X-X-L-(X)6-8-Y-X-X-L), a protein domain involved in STP, binds to SH2 domain, e.g. in CD247/x chain, FceRI g chain, or DAP12. Phosphorylated immunoreceptor signaling motifs (ITAMs) exhibit unique abilities to bind and activate Lyn and Syk tyrosine kinases. Motif may be dually phosphorylated on tyrosine that links antigen receptors to downstream signaling machinery.
A chromosome band present on 2q
2q35-q37
7: 81044003-80976096
Physical location of HGF_Gene
A chromosome band present on 6q
6q27
Olfactory Nerve
First Cranial Nerve
Cranial Nerve I
Glandular Epithelium
Venous System Endothelium
Any of the 32 teeth that replace the deciduous teeth of early childhood.
Permanent Tooth
3q25.1-q26.1
A chromosome band present on 3q
Epitope
Antigenic Determinant
Antigenic Determinants
Binding Determinants
The simplest form of an antigenic determinant, on a complex antigenic molecule, which can combine with antibody or T cell receptor.
Ependymal Cell
Ependymocyte
Ependymal Cells
A cell that lines cavities in the central nervous system. It is considered to be a type of glial cell.
Depressor Labii Inferioris
Physical location of DOC-1R_Gene
11: 67032678-67030545
2q35-q36
A chromosome band present on 2q
Joint of the Rib
Rib Joint
Superior Surface of the Liver
6q26
A chromosome band present on 6q
9: 119211255-119008462
Physical location of DBCCR1_Gene
Physical location of GPS1_Gene
17: 77603052-77608635
White Adipose Tissue
White Fat
ADIPOSE TISSUE, WHITE
Adipose tissue that collects, stores and releases fat in the form of triglycerides. It functions as a heat insulator, mechanical cushion and as a source of energy. White adipose tissue is composed of adipocytes that secrete leptin and other substances that effect energy homeostasis. Its distribution in the body is dependent on the sex of the individual.
Gonadal Cord
Fimbriated End of the Fallopian Tube
The fringed end of the fallopian tube.
It refers to amino acid serine residue that was covalently modified by phosphate group (PO4-). (NCI)
Serine Phosphorylation Site
Ophthalmic Plexus
Fenestra Ovalis
Lingual Salivary Gland
Cartilage Cell
Foot Digit 5
14q32.31
A chromosome band present on 14q
9q32-q33
A chromosome band present on 9q
Auricle Helix
Helix
Immunoglobulin Fc
Fragment Crystallizable Region
Fc Fragment
A protein product that results from the digestion of antibodies with papain and is comprised of the second and third constant regions of the antibody heavy chain.
The first lumbar vertebra counting from the top down.
L1 Vertebra
1: 65603007-65815197
Physical location of LEPR_Gene
6q16.1-q16.3
A chromosome band present on 6q
Middle Thyrohyoid Ligament
Physical location of FOS_Gene
14: 74815284-74818666
Nucleus of the Fifth Nerve
Trigeminal Nuclei
Nucleus of Fifth Nerve
Trigeminal Nucleus
6: 32914499-32897588
Physical location of TAP2_Gene
A conserved amino acid sequence (Tyr-(X)3-Asp) in DNA polymerases that is required for 3' > 5' exonuclease activity.
EXO III Motif
EXO III Domain
Pyloric Gland
Digastric Muscle
Central Nervous System
CNS
Nervous System, CNS
The part of the nervous system that consists of the brain, spinal cord, and meninges.
A chromosome band present on 12q
12q13.1
Cardiac Ventricle
The lower right and left chambers of the heart. The right pumps venous blood into the lungs and the left pumps oxygenated blood into the systemic arterial circulation. (MeSH)
Cardiac Ventricles
Ventricle
Heart Ventricle
HEART, VENTRICLE
Ventricles, Heart
Crural Cistern
An immature (progenitor) cell circulating in the peripheral blood. It has the capacity for replication and differentiation to mature blood cells.
Peripheral Blood Stem Cell
peripheral stem cell
PBSC
Peripheral Blood Stem Cells
Peripheral Stem Cells
17: 29621353-29623369
Physical location of CCL7_Gene
A chromosome band present on 9q
9q32-q34
Medial Tarsal Artery
Parietal Pericardium
Retromolar Trigone
Sartorius Muscle
Tailor's Muscle
Sartorius
Utricle
Prostatic Utricle
A small indentation located in the prostatic urethra, at the apex of the urethral crest, on the seminal colliculus, laterally flanked by openings of the ejaculatory ducts.
Incus
One of the three bones comprising the middle ear. This anvil-shaped bone is positioned between the malleus and the stapes.
Couinaud segment VI, corresponding to the posterior segment of the right lobe of the liver, located inferiorly.
Right Posteroinferior Segment
Couinaud Segment VI
External Pterygoid Muscle
Uterus Serosal Surface
Thyroid Cartilage
A chromosome band present on 8q
8q24.2-q24.3
Alveolar Duct
The respiratory passage distal to the respiratory bronchiole. Alveolar sacs and alveoli arise from the alveolar duct.
Lower Jaw Molar
Any of the molars located in the mandible.
Squamous Alveolar Lining Cell
Squamous Alveolar Lining Cells
A flat, scale-like epithelial cell that forms the inner lining of the alveoli.
A structure located in the middle of the brain. The putamen is part of the basal ganglia and together with the caudate forms the striatum that influences motor activity.
Putamen
Heritable sensitive regions of chromosomes which show up in vitro as non-staining bands. They are associated with chromosome breakage and other aberrations. No abnormal phenotype has been definitely identified with autosomal fragile sites, but some rare autosomal recessive disorders may be due to homozygosity for fragile sites. A fragile site on the X chromosome is associated with Fragile X Syndrome. Fragile sites are designated by the letters "fra" followed by the designation for the specific chromosome and locus.
Fragile Site
Chromosome Fragile Site
Foot Digit 3
Organ System, Gastrointestinal
The system that includes the esophagus, stomach, small and large intestine, anus, liver, biliary tract, and pancreas.
Gastrointestinal System
Body System, Gastrointestinal
Gastrointestinal Body System
Digestive System
Gastrointestinal Organ System
Digestive System (All Sites)
A chromosome band present on Xq
Xq22-q23
Endoneurium
Arteriole
A small, terminal branch in the arterial system. Arterioles often connect to capillaries.
VESSEL, BLOOD
Vessel
Blood Vessel Tissue
The tissue component of a blood vessel. Large vessels contain three layers of tissue, the tunica intima, tunica media, and tunica adventitia. Capillary tissue is composed of a single layer of endothelium and connective tissue.
Adverse Event Body System or Organ Class
The body system or organ class affected by an adverse event.
AEBODSYS
15q11.2
A chromosome band present on 15q.
Hemorrhoidal Plexus
Foot Digit 4
Tissues that contain neurons and supporting cells that form the covers encircling nerves, nerve fibers, and axons.
Nerve Tissue and Nerve Sheaths
SRCR Domain
An amino acid sequence of approximately 100 residues that contains either 6 or 8 cysteine residues, which have conservation of both position and disulfide bond pattern.
Scavenger Receptor Cysteine-Rich Domain
8: 38445293-338389449
Physical location of FGFR1_Gene
Embryonic Integumentary System
Cortical Vein
Neck of the Humerus
Cilium
An organelle that protrudes outward from the cell body. It consists of a specialized arrangement of 9 doublet microtubules in a ring with or without a core of 2 microtubules and is enclosed in a plasma membrane coat. Motile cilia contain the motor protein dynein.
A chromosome band present on 19p
19p13.2-p13.1
Posterior Meningeal Artery
Esophageal Muscularis Mucosa
Fat Droplet
Lipid Inclusion
A detectable aggregation of lipids or membrane fragments in the cytoplasm.
A chromosome band present on 13q
13q14
11p14.3
A chromosome band present on 11p
Carotid Artery
One of two arteries that supply oxygenated blood to the head and neck; the left common carotid branches from the aorta and the right common carotid from the innominate (brachiocephalic artery).
ARTERY, CAROTID
Lower Respiratory Tract Cartilage
A chromosome band present on 15q
15q21.1-q21.2
The skin layer that separates the papillary dermis from the reticular dermis.
Papillary-Reticular Dermal Interface
Left Testis
Yp
The proximal (short) arm of chromosome Y.
Levator Palpebrae Superioris
Communicating Artery
An artery that connects two larger arteries.
3p22-p21.3
A chromosome band present on 3p
Great Cardiac Vein
Commissure
X: 115113885-115117702
Physical location of AGTR2_Gene
Physical location of ACVRL1_Gene
12: 50587469-50601120
Peritoneal Lymph Node
A lymph node located in the peritoneum.
LYMPH NODE, PERITONEAL
The tissue that lines the wall of the thoracic cavity and the surface of the lungs.
Pleural Tissue
Pleura
Bone Marrow Stem Cells
Primitive blood cells residing in the bone marrow, derived from embryonic mesenchyme, and capable of differentiating into any of the blood cell line progenitor cells (erythroblasts, young granulocytic series cells, megakaryocytes, etc.)
Bone Marrow Stem Cell
The valve between the ileum of the small intestine and the cecum of the large intestine.
Ileocecal Valve
SH2-Binding Domain
SH2-Binding Motif
Typically found in signaling proteins, the SH2-Binding Motif mediates regulated high-affinity physical interaction (binding) with the target SH2 (SRC Homology 2) domain. SH2 domains of ~100 amino acids bind to specific phosphotyrosine (pY)-containing motifs with dissociation constants of ~50-500 nM. A conserved pocket of SH2 domains recognizes the pY, and a more variable pocket binds residues C-terminal to pY that confer specificity. SH2 domains balance high affinity for pY and recognition of adjacent residues to allow specific discrimination. The SH2 domain, an anti-parallel b-sheet between a-helices, provides a positively charged b-sheet pocket for binding of pY moieties, and an extended b-sheet surface for binding residues C-terminal to pY. B-sheet surface differences have significant effects on ligand-specificity. (NCI)
7p15-p14.2
A chromosome band present on 7p
Common Iliac Vein
The connective tissue coat of a mucous membrane including the epithelium and basement membrane.
Lamina Propria
Dorsal Motor Nucleus of the Vagus
DMN
Dorsal Motor Nucleus
Ganglion Cell Layer
A chromosome band present on 8p
8p23-p22
A chromosome band present on 13q
13q12
A small fusiform neuroglial cell arranged horizontally in the molecular layer of the cerebral cortex.
Horizontal Cell of Cajal
Walker-A Domain
The ATP binding cassette (ABC) is the largest protein family known and many of its members are membrane proteins (ABC transporters) active in the transport of a wide variety of substances across membranes. ABC proteins are identified by the presence of one or two cytosolically oriented ATP-binding cassettes or nucleotide-binding domains (NBD) of about 200 amino acid residues. Each NBD contains three typical motifs: the Walker A motif, GX4GK(ST), the Walker B motif and the ABC signature or C motif. Walker A and B motifs are found in other nucleotide-binding proteins, including P-, F- and V-ATPases, G proteins, adenylate kinase, myosin, phosphofructokinase and ATP/ADP exchangers. Although the overall similarity between ABC proteins can be very low, their NBDs share an average of 30-40 % similarity.
Walker-A Motif
12q13.3
A chromosome band present on 12q
Septal Cusp
Septal Cusp of the Tricuspid Valve
A primitive, undifferentiated blood cell which can undergo division and will give rise to a cell in the basophil lineage.
Bone Marrow Stem Cell Committed to the Basophil Lineage
Teres Minor Muscle
Epithelium Part
Flexor Carpi Radialis
The middle one of the three pairs of embryonic renal organs developed in most vertebrates; its duct system is retained in the male as the epididymis and ductus deferens.
Wolffian Body
Mesonephros
The entire physical structure of an organism. It is composed of anatomic systems, regions, cavities, and spaces.
Body
A chromosome band present on 1p
1p34-p33
Physical location of EXTL3_Gene
8: 28626893-28667121
Levator Labii Superioris
Physical location of CDH13_Gene
16: 81218079-82387702
A chromosome band present on 12q
12q24.31
Cervical Spine
Those vertebrae immediately behind (caudal to) the skull, C1-C7 in man.
C Spine
First Portion of Duodenum
Superior Portion of Duodenum
Superior Portion of the Duodenum
First Portion of the Duodenum
Mitochondrial
Mitochondria
Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Mitochondria contain distinctive ribosomes, transfer RNAs, amino acyl t-RNA synthetases, and elongation and termination factors. Mitochondria depend upon genes within the nucleus for many essential messenger RNAs. Mitochondria consist of two sets of membranes, a smooth continuous outer coat and an inner membrane arranged in tubules or more often in folds that form platelike double membranes (cristae). Mitochondria are the principal energy source of the cell and contains the cytochrome enzymes of terminal electron transport and the enzymes of the citric acid cycle, fatty acid oxidation, and oxidative phosphorylation. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP.
Mitochondrion
Bronchus-Associated Lymphoid Tissue
Lymphoid tissue located in the bronchi.
BALT
Endometrium
Tunica Mucosa
GLAND, ENDOMETRIAL
The mucous membrane comprising the inner layer of the uterine wall; it consists of a simple columnar epithelium and a lamina propria that contains simple tubular uterine glands. The structure, thickness, and state of the endometrium undergo marked change with the menstrual cycle.
A chromosome band present on 12q
12q22-q23
Carpometacarpal Joint
A chromosome band present on 10p
10p15.1
Bronchus Basal Lamina
Anterior Quadrigeminal Body
Superior Colliculus
The anterior eminence of the lamina tecti mesencephali.
The singular posterior opening of the intestinal and urinary tracts of birds, reptiles, amphibians, marsupials and monotremes.
Cloaca
The sequence of nucleotide residues along a DNA chain.
Sequence
Sequences
DNA Sequence
A chromosome band present on 4q
4q22.1-q23
Isthmus Uteri
Skin Part
Flexural Skin
Extraembryonic Structure
Musculus Latissimus Dorsi
A triangular muscle in the back, connected to the vertebral column, arm, and shoulder. Its action involves adduction, medial rotation, and extension of the arm.
MUSCLE, LATISSIMUS
Mediastinum Part
Muscle of Mastication
Muscles arising in the zygomatic arch that close the jaw.
Stomach Primordium
Physical location of BLR1_Gene
11: 118259777-118272181
Any part of a transmembrane protein that is not embedded within the membrane.
Extramembrane Domain
Internal Geniculate Body
Medial Geniculate Body
The medial one of a pair of small masses that protrude from the posteroinferior part of the thalamus; commonly considered a part of the metathalamus.
Submucous Nerve Plexus
6: 32114061-32117396
Physical location of CYP21A2_Gene
Orbital Part of the Inferior Frontal Gyrus
Physical location of FLT4_Gene
5: 180009172-179962148
A chromosome band present on 6q
6q23.1
The left and right main bronchi considered as a group.
Main Bronchus
16p12.3
A chromosome band present on 16p
Physical location of F2R_Gene
5: 76047542-76067054
7q
Chromosome 7q
Chromosome 7 Distal Arm
Chromosome 7 Long Arm
Distal (long) arm of chromosome 7
10: 112826911-112830560
Physical location of ADRA2A_Gene
A chromosome band present on 8q
8q22.3-q23
Lens-shaped structure on the inner aspect of the internal capsule. The subthalamic nucleus and pathways traversing this region are concerned with the integration of somatic motor function. (MeSH)
Subthalamic Nucleus
Physical location of ALK_Gene
2: 30056083-29327293
Anterior Chamber of the Eye
Anterior Chamber
Anterior Chamber of Eye
Chamber, Anterior
EYE, ANTERIOR CHAMBER
Anterior Chamber (Eye)
The space in the eye, filled with aqueous humor, bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and that part of the crystalline lens which presents through the pupil. (Cline et al., Dictionary of Visual Science, 4th ed, p109)
Xq26.2
A chromosome band present on Xq
Infratentorial Cistern
Hand Plate
Physical location of EBAF_Gene
1: 222435655-222431039
Meibomian Gland
A sebaceous gland in the eyelid that produces a specific type of sebum.
GLAND, MEIBOMIAN
2: 70053968-70077256
Physical location of MAD_Gene
Physical location of GNRHR_Gene
4: 68450570-68434964
The earliest tissue to appear in embryonic development (it is the predominant bone in the developing fetus) and post fracture. The collagenous lamellae are randomly oriented and loosely intertwined. It is characterized by coarse fiber bundles approximately 30 um in diameter.
Immature Bone
Nonlamellar Bone
Bundle Bone
Woven Bone
Lymph Node Germinal Center
Spinal Cord Dura Mater
1: 232323008-232150384
Physical location of CHS1_Gene
Proximal (short) arm of chromosome 7
7p
Chromosome 7 Short Arm
Chromosome 7 Proximal Arm
A projection or projecting structure, or ridge, especially one surmounting a bone or its border.
Crest
Outer Nuclear Layer
Outer Nuclear Layer of the Retina
Outer Nuclear Layer of Retina
Posterior Semicircular Canal
Structures that have evolved from embryonic development of the neural tube. The ependyma is a specialised epithelium lining the ventricles and central canal of the brain and spinal cord. The remnants of the central canal of the spinal cord represent modified ependyma left from embryonic development of the neural tube
Ependyma and Remnants of the Central Canal of the Spinal Cord
A chromosome band present on 14q
14q31-q32.1
Bile Duct Epithelium
A thin pliable sheet separating organelles from the protoplasm.
Intracellular Membrane
Flexor Carpi Ulnaris
Longissimus Capitis
A chromosome band present on 15q
15q24-q25
4p15.1
A chromosome band present on 4p
A chromosome band present on 6p
6p25
Physical location of MMP14_Gene
14: 22375633-22386643
Breast
Breasts
One of two hemispheric projections of variable size situated in the subcutaneous layer over the pectoralis major muscle on either side of the chest.
Foot Digit 4 Phalanx
A cell whose cytoplasm or its granules stain with acid dyes.
Acidophilic Cell
Macula Lutea
Gastrointestinal Sphincter
Osteoid
A protein mixture secreted by osteoblasts. When the protein mixture mineralizes, it becomes bone. Osteoid is primarily composed of type 1 collagen.
Serratus Ventralis
ARTERY, MAMMARY
Internal Thoracic Artery
The blood vessel that supplies the breast and the anterior chest wall with arterial blood. It is located in the chest wall.
Internal Mammary Artery
Irregular Tubule
15q11-q13
A chromosome band present on 15q.
Head of the Fibula
Cochlear Duct
Xq26.1
A chromosome band present on Xq
A chromosome band present on 3p
3p21-p14
Phrenic Artery
Fascicle
A small bundle of nerve fibers that is more or less associated functionally.
3q23-q24
A chromosome band present on 3q
Tertiary Protein Structure
Tertiary structure describes the folding of the polypeptide chain to assemble the different secondary structure elements in a particular arrangement.
X: 9897925-9900718
Physical location of CSF2RA_Gene
Embryologic Structure
A body part, organ or organ component that is formed during the embryonic stage of life of an organism.
Embryonic Structure
Intrahepatic Bile Duct
The bile ducts that pass through and drain bile from the liver.
10q24.1
A chromosome band present on 10q
The upper tract of the renal system. The renal pelvis is the large cavity in the middle of each kidney. Urine drains from each kidney through a long tube called the ureter, into the bladder, where it is stored until it is passed from the body through the urethra.
Renal Pelvis and Ureter
Inferior Epigastric Artery
Desmoplakin
Labium
Ophthalmic Nerve
6p23
A chromosome band present on 6p
Corticotrope Cell
Corticotroph
ACTH Cell
Corticotroph Cell
Physical location of CD22_Gene
19: 40511953-40530104
10q21.1
A chromosome band present on 10q
Nerve Sheath
A protective cover encircling a nerve, nerve fiber or axon.
EYE, IRIS
Iris
The colored disc of the eye composed of connective tissue, epithelium, and endothelium. It separates the anterior chamber from the posterior chamber.
Pulmonary Lobule
The smallest anatomical unit of the lung, measuring 0.50 to 2.00 cm in diameter. Each lobule is composed of 4-8 terminal bronchioles and their distal alveolar ducts and sacs. The lobules are separated by fibrous interlobular septa.
Lung Parenchyma
LUNG
Tissue consisting of an external serous coat, subserous areolar tissue and lung parenchyma. The parenchyma is made up of lobules wound together by connective tissue. A primary lobule consists of a terminal bronchiole, respiratory bronchioles, and alveolar ducts, which communicate with many alveoli, each alveolus being surrounded by a network of capillary blood vessels.
Lung Tissue
A sequence in DNA that can be recognized by a specific restriction enzyme.
Restriction Site
Restriction Enzyme Recognition Site
Restriction Enzyme Site
Nasopharynx Epithelium
The non-glandular tissue of the prostate gland, consisting of two major cell types, smooth muscle cells and fibroblasts. Stromal cells are key regulators of growth and differentiation in the prostate.
Prostatic Stroma
Stroma of Human Prostate Gland
Stroma of the Prostate Gland
Pyramidal Cells
Pyramidal Cell
Projection neurons in the cerebral cortex and the hippocampus. Pyramidal cells have a pyramid-shaped soma with the apex and an apical dendrite pointed toward the pial surface and other dendrites and an axon emerging from the base. The axons may have local collaterals but also project outside their cortical region. (MeSH)
6p24
A chromosome band present on 6p
Masseteric Vein
1q42.1
A chromosome band present on 1q
Intermediate Mesoderm
Testicular Vein
Internal Spermatic Vein
Spermatic Vein
A microtubule that is part of a cilium.
Cilium Microtubule
Organ
A unique macroscopic (gross) anatomic structure that performs specific functions. It is composed of various tissues. An organ is part of an anatomic system or a body region. Representative examples include the heart, lung, liver, spleen, and uterus.
Digital Vein
The middle portion of the brainstem located between the midbrain and the medulla oblongata. The fourth ventricle lies dorsal to the pons which also contains the motor trigeminal nuclei and the abducens nuclei. The cerebellum contributes a large number of afferent fibers to the pons.
Pons Varolii
Pons Cerebelli
Pons
Bronchus
Bronchi
Tubular structure in continuation with the trachea, serving as air passage. It terminates in the lung (terminal bronchiole).
A chromosome band present on 10q
10q24.3
9q21.32
A chromosome band present on 9q.
1: 147662259-147595259
Physical location of ARNT_Gene
Type I Cell
Type I Epithelial Receptor Cell
A dark cell found in taste buds. It is rich in free ribosomes, tubular RER and has large dense granules and exhibits AbH immunoreactivity.
Anterior Jugular Vein
A vein arising near the hyoid bone from several veins from the submaxillary region. It terminates in the external jugular vein.
Mesothelial Cell
A flat cell of mesenchymal origin that forms the superficial layer of the serosal membranes lining the body cavities of the abdomen and thorax.
6p21
A chromosome band present on 6p
One of the neural pathways that transmit impulses from the eyes to the cerebral cortex.
Anterior Visual Pathway
Organ systems involved in self-stimulation through cellular production of a factor and a specific receptor for it.
Autocrine
Autocrine Systems
Red blood corpuscule
Red Cell
RBC
RBC - Red blood cell
Red cells
Red Blood Cells
Erythrocytes
Blood erythrocyte
Blood normocyte
Erythrocyte
Red cell of marrow
Erythrocytic
Cell specialized for oxygen transport, having a high concentration of hemoglobin in the cytoplasm and little else; biconcave, anucleate discs, 7nm diameter in mammals.
blood corpuscles
Reticuloendothelial System, Erythrocytes
red blood cell
A stretchable connective tissue membrane that is the outermost component of the tunica intima, delineating the border between the tunica media and the tunica intima.
Internal Elastic Membrane
Tensor Tympani
Physical location of HIF1A_Gene
14: 61231992-61284729
Lamina Rara Externa
Breast Lobe
The teeth collectively in the dental arch. Dentition ordinarily refers to the natural teeth in position in their alveoli. (MeSH)
Dentition
Oval Subthalamic Nucleus
Oval Nucleus
9p11.2
A chromosome band present on 9p
14: 94693512-94622319
Physical location of DICER1_Gene
Bowel
Intestines
The portion of the gastrointestinal tract between the stomach and the anus. It includes the small intestine and large intestine.
Intestine
Head and Neck, Thyroid
Thyroid
Thyroid Gland
An endocrine gland located at the base of the neck that produces and secretes thyroxine and other hormones. Thyroxine is important for metabolic control.
Obturator Vein
Physical location of BIRC3_Gene
11: 101693404-101713675
A complex group of fibers arising from the basal olfactory regions, the periamygdaloid region, and the septal nuclei, and passing to the lateral hypothalamus. (MeSH)
Medial Forebrain Bundle
A chromosome band present on 6p
6p22
Physical location of BCL2L1_Gene
20: 29774317-29715924
Inferior Vesical Artery
An opening in the hip bone formed by the public bone and the ischium and closed by the obturator membrane.
Obturator Foramen
Obturator
Class V
Class V Surface
The gingival margins of the tooth surfaces.
Physical location of ADAMTS9_Gene
3: 64648405-64476373
A chromosome band present on 1q.
1q31.3
Articular Muscle
A muscle that inserts directly onto the capsule of a joint, acting to retract the capsule in certain movements.
2: 240058897-239706636
Physical location of HDAC4_Gene
13: 102296421-102326346
Physical location of ERCC5_Gene
A protein motif containing a phosphorylated serine residue. These motifs can influence both protein-protein interactions and cellular signaling.
Phosphoserine Motif
Phosphoserine Domain
A chromosome band present on 13q
13q21
Cartilage Matrix
The final section of the small intestine.
SMALL INTESTINE, ILEUM
Ileum
A chromosome band present on 22q
22q13.1-q13.2
16q12
A chromosome band present on 16q
Umbilical Region
A perivascular cell with abundant clear or eosinophilic cytoplasm that contains glycogen. -- 2005
PEC
Perivascular Epithelioid Cell
Cementocyte
A cell in a hollow cavity of cellular cementum, ranging in shape from round to oval or flattened, and exhibiting numerous protoplasmic processes extending from its free surface.
Cerebral tissue composed of cells with distinctive characteristics. The cerebral cortex contains six cell layers.
Cortical Cell Layer of the Cerebral Cortex
BRAIN, CEREBRUM
Cerebral Hemispheres
Cerebrum
12q11-q13
A chromosome band present on 12q
A reticular epithelial cell generated in the thymus that, in optimal condition, can become a cortex type of thymus cell that mediates positive selection of developing thymocytes.
Thymic Epithelial Cell Capable of Differentiating Towards Cortical Cell Type
Foot Digit 2
A lymph node located beneath the floor of the oral cavity.
LYMPH NODE, SUBMANDIBULAR
Lymph Node, Mandibular
Submandibular Lymph Node
The first part of the colon (large intestine) that starts in the right lower quadrant of the abdomen and ends at the transverse colon in the right upper quadrant of the abdomen.
Right Colon
COLON, ASCENDING
Ascending Colon
Eleventh Cranial Nerve
Spinal Accessory Nerve
The 11th cranial nerve, which sends motor impulses to the muscles of the upper thorax, back, shoulders, and pharynx.
Accessory Nerve
Sinonasal Tract
Squamous Cells
Squamous Cell
median umbilical ligament
The urinary canal of the fetus; postnatally it is usually a fibrous cord but occasionally persists as a vesicoumbilical fistula. (MeSH)
Urachus
Lower Jaw Incisor
Either of the incisors found in the mandible.
A chromosome band present on 16q
16q13
Chyle Cistern
8: 109330128-109283148
Physical location of EIF3S6_Gene
Large Intestinal Mucosa
Mucosa consisting of the epithelium, basement membrane, lamina propria mucosae and lamina muscularis mucosae of the distal portion of the digestive tract from the small intestine to the anus.
A chromosome band present on 12q
12q11-q14
Foot Digit 1
Liver Fissure
Any of the clefts or grooves on the surface of the liver.
Greater Multiangular Bone
Trapezium
Trapezial Bone
A carpal bone on the thumb side of the hand that articulates with the 1st and 2nd metacarpals.
Lacrimal Gland
GLAND, LACRIMAL
Paired, almond-shaped exocrine glands situated superior and posterior to each orbit of the eye that produce and secrete the watery serous component of tears.
Large Intestinal Lamina Propria
Urethra Epithelium
Uterine Gland
Mucus gland in the endometrium.
11: 111540050-111519186
Physical location of IL18_Gene
A chromosome band present on 17q
17q21.3-q22.1
Urogenital Sinus
A cell whose cytoplasm or granules stain readily with basic dyes.
Basophilic Cell
6: 106915002-107125017
Physical location of AIM1_Gene
A chromosome band present on 9q
9q31.3-q32
Obturator Externus Muscle
Right Lung Alveolus
Ilium
Iliac
BONE, ILIUM
The broad, dorsal, upper, and widest of the three principal bones composing either half of the pelvis.
3p21.33
A chromosome band present on 3p.
Physical location of IL10_Gene
10: 203334234-203329343
The cavity lined by the pleura, located in the thorax and contains heart and lungs.
BODY CAVITY, PLEURAL
Pleural Cavity
Muscle Layer
Muscularis
The smooth muscle component of an organ, especially of a hollow organ or tubular structure.
The flat triangle-shaped bone that connects the humerus with the clavicle in the back of the shoulder.
Scapula
BONE, SCAPULA
Shoulder Blade
A chromosome band present on 6q
6q25.2-q26
A soft yellow wax secreted by glands in the ear canal.
Earwax
Cerumen
Physical location of CYP11B1_Gene
8: 143958238-143952218
Eye Part
Fibroblast
Fibroblasts
An intracranial venous sinus that lies in a midline location along the lower free border of the falx cerebri of the brain. The sinus receives blood from the great cerebral vein and joins the superior sagittal sinus posteriorly.
Sagittal Sinus, Lesser
Lesser Sagittal Sinus
Sagittal Sinus, Inferior
Inferior Sagittal Sinus
3p21.31
A chromosome band present on 3p
A not-yet-mature white blood cell with staining granules in its cytoplasm. The staining granules may be neutrophilic, acidophilic, or basophilic in character. There are indications that an immature granulocyte count is a better measure of infection and sepsis than a total white blood cell count and comparable to absolute neutrophil count.
Immature Granulocyte
Distal Enhancer Elements
Enhancer sequences found at a distance from the gene it regulates.
Maxillary Prominence
Capsular Ligament
Usually C-terminal, the conserved ETS (Erythroblast Transformation Specific) Domain of 85-90 amino acids, rich in positively-charged and aromatic residues, binds to purine-rich DNA with a GGAA/T core. Identified in many transcription factors, many ETS-proteins modulate gene expression through protein-protein interactions with other transcriptional factors and co-factors. Most ETS-proteins are nuclear targets of RAS-MAPK signaling; some affect cell proliferation or apoptosis-related genes. Several are expressed in specific cell lineages to regulate development and differentiation. Deregulated ETS-gene expression or chimeric ETS-proteins are associated with leukemias, some tumors, invasion and metastasis. (NCI)
ETS Domain
Physical location of DNMT3B_Gene
20: 30813852-30860823
Pancreas Tail
Tail of Pancreas
PANCREAS, TAIL
Pancreatic Tail
The left extremity of the pancreas within the lienorenal ligament.
Tail of the Pancreas
17q11.2-q12
A chromosome band present on 17q
A protein complex associated with the distal end of the centriole that is involved in centriole localization.
Proximal Connecting Fiber
BODY CAVITY, PERICARDIAL
Pericardial Cavity
The potential body space formed between the parietal and visceral layers of the pericardial sac.
Perforant Pathway
A pathway of fibers originating in the lateral part of the entorhinal area, perforating the subiculum of the hippocampus, and running into the stratum moleculare of the hippocampus, where these fibers synapse with others that go to the dentate gyrus. It is also called the perforating fasciculus. (MeSH)
Perforating Fasciculus
Right Main Bronchus
MAIN BRONCHUS, RIGHT
One of the two main bronchi. It is wider but shorter than the left main bronchus and connects to the right lung.
Pigmented Epithelium
Pigment Epithelium
Tissue consisting of one or more layers of epithelial cells and a basement membrane. The cells contain granules of pigment or melanin, as in the retinal or iris pigment layer.
Blood Island
Descending Limb of Henle's Loop
Duct carrying spermatozoa.
Vas Deferens
X: 117643441-117710378
Physical location of IL13RA1_Gene
Physical location of IGF2R_Gene
6: 160360542-160497994
Large sensory ganglion of the trigeminal nerve that lies adjacent to the cavernous sinus in the trigeminal cavity of the dura mater.
Trigeminal Ganglion
GANGLION, TRIGEMINAL
Gasserian Ganglion
Colorectal Zone of the Anal Canal
2: 204396704-204428062
Physical location of CD28_Gene
A chromosome band present on 2q
2q33.3-q34
Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components from interstitium to lumen. (MeSH)
Vascular Endothelium
Cardinal Vein
A conical membranous sac filled with serous fluid in which the heart as well as the roots of the aorta and other large blood vessels are contained.
Pericardium
The N-terminal sequence of a protein that is required to direct the localization of a cytoplasmic protein to a subcellular membrane-bound organelle.
Transit Domain
Transit Peptide Domain
Transit Sequence
Transit Peptide
Physical location of HDAC1_Gene
1: 32426801-32468317
Endocardial
Endocardium
The layer of endothelial cells and connective tissue lining the chambers of the heart.
Portal Venous System
A system of vessels in which blood, after passing through one capillary bed, is conveyed through a second set of capillaries before it returns to the systemic circulation. It pertains especially to the hepatic portal system.
Portal System
Thymocytes
Thymocyte
A cell that develops in the thymus, seemingly from a stem cell of bone marrow and of fetal liver, and is the precursor of the thymus-derived lymphocyte (T lymphocyte) that effects cell-mediated (delayed type) sensitivity.
Sustentacular Cell of Testis
Sertoli Cells
Sertoli Cell
Elongated cells in the seminiferous tubules to which spermatids are attached during spermiogenesis; they secrete androgen-binding protein and establish the blood-testis barrier by forming tight junctions with adjacent Sertoli's cells.
PXXP Motif
PXXP Domain
The SH3 domain, often seen in signaling pathway proteins, frequently binds to a conserved PXXP Motif usually found in proline-rich regions of target proteins. The SH3 domain contains a site located between the RT and n-SRC loops that binds the PXXP motif, which then adopts a poly-proline type II (PPII) conformation. PXXP motifs are often clustered and have residues that contribute to binding specificity. Class I motifs have an amino to carboxy terminal binding orientation and include sites specific for the SRC oncoprotein. More promiscuous in their binding, Class II motifs have a carboxy to amino terminal binding orientation, PXXP can be in either of two positions, and they have basic residues at the C-terminus. (NCI)
Optic Stalk
Temporal Sulcus
Prostate Gland Secretion
5q34-q35
A chromosome band present on 5q
Metamyelocyte
A cell derived from a promyelocyte and differentiates into a neutrophil. It is nonproliferative and is usually found in bone marrow. Its nucleus is indented and the chromatin clumped and dense.
5: 174803769-1748006433
Physical location of DRD1_Gene
LUNG, RIGHT LOWER LOBE
The lobe of the right lung situated below the oblique fissure.
Lower Lobe of Right Lung -RLL
Lower Lobe of the Right Lung -RLL
Lung Right Lower Lobe
Lower Lobe of the Right Lung
Inferior Lobe of the Right Lung
A chromosome band present on 1p
1p34.1
Physical location of GLI2_Gene
2: 121266089-121465186
15q21.2
A chromosome band present on 15q
Spiral Artery of the Endometrium
Spiral Artery
Vertebral Joint
Joint of the Vertebra
3p21
A chromosome band present on 3p
Posterior Portion of the Corpus Callosum Cistern
Endometrial Stromal Cell
A cell of the uterine wall immediately underling the endometrial epithelium. Endometrial stromal cells proliferate and respond to the cyclic variations of estrogen and progesterone. These cells produce growth factors and hormones that mediate the proliferative response of epithelial cells to the steroid hormones estrogen and progesterone. In response to embryo implantation, endometrial stromal cells accumulate lipid and glycogen.
Head Skin
Spinalis Thoracis
Sclerotome
Myotome Region
Colorectal Region
Physical location of BMP15_Gene
X: 50486820-50492643
Superior Hypophyseal Artery
External Capsule
Physical location of FRSB_Gene
2: 223346310-223260765
Sphenoorbital Region
3q27.3
A chromosome band present on 3q
A chromosome band present on 6q
6q21-q22.1
Posterior Wall of the Hypopharynx
Posterior Wall of Hypopharynx
1: 147365209-147360110
Physical location of MCL1_Gene
3p22
A chromosome band present on 3p
Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC). NPC is comprised of approximately 50 unique proteins collectively known as nucleoporins. NPC functions in the nuclear transport of protein and RNA. (NCI)
NPC
Nuclear Pore Complex
A DNA structure formed between similarly oriented, homologous DNA double strands in which a single strand from one duplex crosses over to base pair with the complimentary strand on the other duplex, generating a cruciform structure. Such structures are an intermediate in homologous recombination that is conserved from yeast to humans. The branches of a Holliday junction are ordinarily resolved by cleavage of two of the DNA strands. This yields double stranded daughter DNA duplexes with combinations of genes that may be unique from those of the parent duplexes.
Holliday Structure
Holliday Junction
A terminal branch of the sciatic nerve. It innervates the calf and foot.
NERVE, PERONEAL, COMMON
Common Peroneal Nerve
An artery that originates from the basilar artery and distributes blood to the cerebellum.
Cerebellar Artery
Physical location of CTSL_Gene
9: 87570534-87575862
Locus
Gene Locus
The position of a gene or a chromosomal marker on a chromosome; also, a stretch of DNA at a particular place on a particular chromosome. The use of locus is sometimes restricted to mean regions of DNA that are expressed.
Transverse Colon
The third division of the colon (large intestine). It communicates with the ascending colon in the upper right-hand quadrant of the abdomen and the descending colon in the upper left-hand quadrant.
COLON, TRANSVERSE
The supporting connective tissue of an organ.
Connective and Soft Tissue
Response Elements
Nucleotide sequences, usually upstream, which are recognized by specific regulatory transcription factors, thereby causing gene response to various regulatory agents. These elements may be found in both promotor and enhancer regions.
Genital System, Male, Fluids, Secretions
Sperm, Fluids, Secretions
Male Genital System Fluids and Secretions
Male Genital System Fluid or Secretion
Sperm and the fluid it is suspended in.
22q12.1-q13.2
A chromosome band present on 22q
A cluster of chromaffin cells derived from the neuroectoderm and located adjacent to the adrenal gland, nerves, and blood vessels.
Chromaffin Body
paraganglia
Paraganglion
Axis of the Centriole
Meningeal Nerve
Immunoreceptor Tyrosine-Based Motif
Short sequences of amino acids that contain tyrosine and are found in immunoglobulin receptor proteins. Phosphorylation of the tyrosine can influence signal transduction.
Post-Translational Modification Site
A post-translational modification site refers to amino acid residues within a peptide that act as acceptors for any modifications that do not happen concurrent with translation.
6q21-q22.3
A chromosome band present on 6q
3q27.1
Part of the chromosome bands present on the long (q) arm of chromosome 3.
Sixth Cranial Nerve Nucleus
The cranial nerve nucleus from which the abducens nerve originates from. It is located in the middle portion of the brain stem.
Abducens Nucleus
Physical location of GRIA3_Gene
X: 122043693-122348328
DNA replication is a process that allows two new double helixes of DNA to be created from one double helix. During replication, Y-shaped regions of replicating DNA molecules are mobilized, where the enzymes replicating a DNA molecule bind to an untwisted, single DNA strand. This Y-shaped region is referred to as a replication fork. Bacteria and viruses only process one replication fork at a time, while eukaryotic DNA has many replication forks moving along DNA strands at the same time.
DNA Replication Fork
Perivascular Myoid Cell
Myopericyte
The hinge synovial joints between the phalanges of the fingers.
Interphalangeal Joint of the Hand
prevascular space
MEDIASTINUM, ANTERIOR
The area between the lungs; it contains the thymus, some lymph nodes, and vessels and branches of the internal thoracic artery.
Anterior Mediastinum
An embryonic cell on the dorsal surface of the early vertebrate embryo that gives rise to the cells of the nervous system
Neuroectodermal Cell
The air that is inhaled and exhaled during respiration.
Breath
3p24
A chromosome band present on 3p
Interstitial Cell of Cajal
A specialized cell found throughout the gastrointestinal tract. These cells are essential for normal gastrointestinal motility by functioning as the pacemaker cells in gastrointestinal muscles. They mediate or transduce inputs from enteric motor nerves to the smooth muscle syncytium.
Tooth Bud
Part of the chromosome bands present on the long (q) arm of chromosome 9.
9q34.11
Gastrula
Dermo-Epidermal Junction
Intrahepatic Bile Duct Epithelium
Epithelium composed of one or more layers of glandular epithelial cells and a basement membrane lining the lumen of the intrahepatic bile duct.
Hand Digit 5 Phalanx
Nasopharynx
The part of the pharynx in the back of the throat, at and above the soft palate. The nasopharynx is continuous with the nasal passages.
Transitional Epithelium of the Urinary Tract
Transitional epithelium lining the renal pelvis, bladder, ureter, and part of the urethra.
Urothelium
Intercostal Muscle
A muscle located between two ribs.
MUSCLE, INTERCOSTAL
Respiratory Muscles
21q22.11
A chromosome band present on 21q
Popliteus Muscle
Intercostal Nerve
The space bounded by the nine microtubule triplets of the centriole.
Internal Lumen of the Centriole
Physical location of BCL2_Gene
18: 59137025-58941558
Photosensitive Region of the Retina
The system of muscles, tendons, ligaments, bones, joints and associated tissues that move the body and maintain its form.
Musculoskeletal System
Vitelline Vein
Angular Gyrus
The portion of the brain located in the parietal lobe that plays a role in intersensory processing, language comprehension, and cognition.
5q23.2
A chromosome band present on 5q
Dorsal Nucleus of the Vagus Nerve
A cell of the corpus luteum that is derived from the inner layer of the sheath surrounding the graafian follicle.
Theca Lutein Cell
Chondrocranium
9q34.13
A chromosome band present on 9q
20pter-p12
A chromosome band present on 20p
Endocrine Reproductive Tissue
Dorsal Curve
Drug Binding Site
The reactive parts of a macromolecule that directly participate in its specific combination with a drug.
4q34.1-q34.3
A chromosome band present on 4q
7q21.11
A chromosome band present on 7q
Superficial Vein
Inferior Frontal Sulcus
Physical location of GTF2A1_Gene
14: 80757328-80716147
Astragalus
The bone of the foot that connects with the tibia and fibula to form the ankle joint.
Talus
Superior Anastomotic Vein of Trolard
Physical location of GNAI2_Gene
3: 50248652-50271291
19: 54219405-54217939
Physical location of CGB_Gene
A chromosome band present on 12q
12q23-q24.1
Acetyl Group
11: 69165054-69178423
Physical location of CCND1_Gene
15q21.1
A chromosome band present on 15q
The sequence of nucleotide residues along an RNA or DNA chain.
Nucleotide Sequence
Sequence
Globus Pallidus
The representation of the phylogenetically oldest part of the corpus striatum called the paleostriatum. It forms the smaller, more medial part of the lentiform nucleus. (MeSH)
Synarthrosis
Immovable articulation by close union, as in sutures.
The second cranial nerve.
Second Cranial Nerve
NERVE, OPTIC
Optic Nerve
Primordial Gut
A nervous tract that transmits pain, temperature, and touch sensations and position and vibratory sense to the brain.
Ascending Spinal Cord Tract
Ascending Tracts of Spinal Cord
Ascending Spinal Cord Tracts
Ascending Spinal Tracts
Physical location of COX7A2L_Gene
2: 42500007-42489298
Gastrointestinal System Lamina Propria
Alimentary System Lamina Propria
Right Hypochondriac Region
Zone 1
Zone 1 of the Lliver Acinus
Zone 1 of Lliver Acinus
Liver Acinus Zone 1
10: 62208242-62223930
Physical location of CDC2_Gene
Distal (long) arm of chromosome 20
Chromosome 20 Distal Arm
Chromosome 20 Long Arm
20q
2q34-q35
A chromosome band present on 2q
7: 143500552-143515372
Physical location of ARHGEF5_Gene
Nasal Cartilage
Internal Pubic Artery
Corium
Cutis
Dermis
Rough ER
Rough-Surfaced Endoplasmic Reticulum
Granular Endoplasmic Reticulum
rER
Ergastoplasm
Rough Endoplasmic Reticulum
Membrane organelle of eukaryotes that forms sheets and tubules. Contains the receptor for the signal receptor particle and binds ribosomes engaged in translating mRNA for secreted proteins and the majority of transmembrane proteins. Also a site of membrane lipid synthesis. The membrane is very similar to the nuclear outer membrane. The lumen contains a number of proteins that possess the C terminal signal KDEL.
Sclera
White of Eye
EYE, SCLERA
The white, opaque, fibrous, outer tunic of the eyeball, covering it entirely excepting the segment covered anteriorly by the cornea. It is essentially avascular but contains apertures for vessels, lymphatics, and nerves. It receives the tendons of insertion of the extraocular muscles and at the corneoscleral junction contains the canal of Schlemm. (From Cline et al., Dictionary of Visual Science, 4th ed)
Physical location of CUL4A_Gene
13: 112912288-112967400
Recto-Vesical Pouch
Chromosome 20 Proximal Arm
Chromosome 20 Short Arm
Proximal (short) arm of chromosome 20
20p
A chromosome band present on 17q
17q12-q21
Physical location of DLEU2_Gene
13: 49554115-49515574
External Carotid Artery
A chromosome band present on 15q.
15q25.1
1q32-q41
A chromosome band present on 1q
Physical location of GLTSCR1_Gene
19: 52874031-52898291
22: 45253586-45077250
Physical location of CELSR1_Gene
Epithelium derived from the ectoderm of the dental lamina. It is found on the upper part of the bell or cap of the enamel organ of the developing tooth and is composed of cuboidal cells.
Outer Enamel Epithelium
An organ that is part of the hematopoietic and immune systems. It is composed of the white pulp and the red pulp and is surrounded by a capsule. It is located in the left hypochondriac region. Its functions include lymphocyte production, blood cell storage, and blood cell destruction.
Reticuloendothelial System, Spleen
Splenic
Spleen
Primordial Myocardium
A chromosome band present on 16p
16p13.3
A chromosome band present on 10q
10q25.3-q26.1
Physical location of D10S170
10: 61336314-61218528
Infusion Site
The anatomic site through which fluid is introduced into the body.
SITE, INFUSION
2: 120819229-120825204
Physical location of INHBB_Gene
Internal ribosome entry site (IRES) is a translational cis-acting element that directs ribosomes to the start codon by a cap-independent mechanism. IRESs are usually about 450 nucleotides in length and were first identified in picornavirus RNAs. IRESs can fold into a stable secondary hairpin structure to be incompatible with efficient translation by ribosomal scanning. (NCI)
IRES
Ribosome Entry Site
Internal Ribosome Entry Site
The extracellular facing lipid layer of the plasma membrane.
Outer Leaflet of the Lipid Bilayer
Oncocytes
Askenazy Cells
Oncocyte
Oxyphil Cells
Oxyphilic Cell
Oxyphil Cell
A glandular cell with acidophilic cytoplasm that contains tightly packed mitochondria. Oxyphil cells are found in the thyroid gland (Hurthle cells) and parathyroid gland.
Body of the Pancreas
The part of the pancreas from the point where it crosses the portal vein to the point where it enters the lienorenal ligament.
Pancreatic Body
Body of Pancreas
PANCREAS, BODY
Pancreas Body
Chyle
Navicular Bone
An oval-shaped bone of the tarsus found on the medial side of the foot.
External Lip
External Lip, NOS
4: 75329947-75327791
Physical location of CXCL2_Gene
A supporting structure of the shoulder consisting of the muscles and tendons that attach the arm to the shoulder joint and enable the arm to move.
Rotator Cuff
Exocrine Pancreas Cell
3: 39423209-39428929
Physical location of LAMR1_Gene
Physical location of SMARCD2_Gene
17: 59274083-59263176
In humans, the glands of the breast, consisting of fibrous tissue connecting the lobes and fatty tissue in between the lobes.
Mammary Gland
TARSUS BONE
Bone, Tarsal
The seven bones which form the tarsus; namely the calcaneus, talus, cuboid, navicular, and first, second and third cuneiforms. The tarsus is a skeletal part of the foot.
BONE, TARSUS
Tarsal Bone
Tarsus
Tarsal Bones
A functional area or structure in a cell that is bounded by a lipid-containing membrane.
Membrane-Limited Cytoplasmic Organelle
Membranous Cytoplasmic Organelle
Uvula
The fleshy lobe that hangs at the back of the soft palate.
Palatine Uvula
6: 3064041-3098288
Physical location of BPHL_Gene
3p25
A chromosome band present on 3p
16p13.1
A chromosome band present on 16p
Deep Vein
Serous Salivary Gland
GLAND, SALIVARY, SEROUS
Salivary glands that produce and secrete a saliva made up exclusively of a pale-yellow transparent fluid containing amylase.
Physical location of CHEK2_Gene
22: 27465251-27408285
The interface between the more apically located alveolar mucosa and the more coronally located gingiva.
Mucogingival Junction
Physical location of GTF2E1_Gene
3: 121952059-121984605
Inverted Y Radiation Field
A radiation field that covers the anterior chest well in the shape of an inverted 'Y'. It includes the inguinal, femoral, pelvic, and para-aortic nodal area.
Inverted Y
Inverted Y Field
20q11.2-q13.1
A chromosome band present on 20q
A chromosome band present on 12q
12q24.21
The junction of the upper distal end of the scapula to the distal edge of the collarbone, also known as the acromion and the clavicle.
Acromioclavicular Joint
A higher order chromatin structure above the level of the chromatin fiber. The organization of chromatin into loops permits the partitioning of chromatin into topologically independent domains, and is thought to facilitate its compartmentation into functionally independent regions.
Chromatin Loop
DNA Loop
Chromatin Loop Domains
Spermatic
zoosperm
Spermatozoa
Sperm
Spermatozoon
The male reproductive cell that is formed in the testicle. A sperm consists of a head, a body, and a tail that provides propulsion.
Sentinel Node
SLN
The first lymph node that is affected by cancer spread from the primary site. Sentinel lymph node biopsy is part of the staging work-up to determine early metastasis to regional lymph nodes in patients with breast carcinoma or melanoma.
Sentinel Lymph Node
Vomer
A thin, paired or unpaired, trapezoidal bone of the skull located in the floor of the nasal cavity. The vomer forms the posterior and inferior parts of the nasal septum.
Bile Canaliculus
Physical location of ETV6_Gene
12: 11694055-11939603
Hyoglossus Muscle
Hyoglossus
Hyoglossal Muscle
Proprioceptor
Proprioceptive Sensory Neuron
Physical location of CTSD_Gene
11: 1741798-1730561
Proximal (short) arm of chromosome X
Chromosome X Short Arm
Chromosome X Proximal Arm
Xp
Facet Joint
A synovial joint between two adjacent vertebrae. The facet joint links the articular process of one vertebra and the inferior articular process of the adjacent vertebra.
Zygapophyseal Joint
Uterine Body
Uterus, Corpus
Corpus
The Corpus uteri, or body of uterus, is the part of the uterus above the isthmus, comprising about two thirds of the non-pregnant organ.
Corpus Uteri
4: 75269440-75267349
Physical location of CXCL3_Gene
C7 Vertebra
The seventh of the seven cervical vertebrae.
Membrane Localization Motif
An amino acid sequence that directs a protein to become localized in or at the cell membrane. This targeting is determined either by the presence of hydrophobic amino acid residues or by post-translational modification that adds a hydrophobic molecule to the protein at this site.
Membrane Localization Domain
Physical location of CKB_Gene
14: 103058923-103055749
Physical location of POU2F2_Gene
19: 47328422-47286963
Thoracic Esophagus
Clinical esophageal segment composed of smooth muscle. It includes the middle third topographic segment, as well as parts of the upper and lower thirds.
ESOPHAGUS, THORACIC
Restriction Enzyme Cut Site
Restriction Enzyme Cleavage Site
The specific DNA base that is cut by a specific restriction enzyme.
Chromosome X Distal Arm
Chromosome X Long Arm
Xq
Distal (long) arm of chromosome X
A chromosome band present on 1p
1p34.3
The muscle of the upper arm that extends the forearm.
MUSCLE, TRICEPS BRACHII
Triceps Brachii
Labial Artery
A chromosome band present on 9q
9q32-q33.3
A pear-shaped organ located under the liver that stores and concentrates bile secreted by the liver. From the gallbladder the bile is delivered through the bile ducts into the intestine thereby aiding the digestion of fat-containing foods.
Gallbladder
Gallbladder / Biliar
Gall Bladder
Gastrointestinal Tract, Gall Bladder
Gallbladder/Biliary system
The depression or scar on the abdomen that marks the former site of attachment of the umbilical cord.
Umbilicus
Belly Button
Navel
18q21.1-q21.32
A chromosome band present on 18q
Physical location of ADORA3_Gene
1: 111758785-111754097
2: 172604482-172674045
Physical location of HAT1_Gene
17: 32368612-23274607
Physical location of LHX1_Gene
Olecranon
A prominence at the proximal end of the ulna. It forms the tip of the elbow.
Incisal Edge
The cutting edge of an incisor tooth.
Pancreas Part
A chromosome band present on 17q
17q21.32
A chromosome band present on 6q
6q24-q27
Physical location of FGF1_Gene
5: 142045812-141953308
Triceps Surae
Head of the Tibia
Kidney Part
Body of the Spermatozoon
A chromosome band present on 22q
22q12.1
2: 204558017-204564189
Physical location of CTLA4_Gene
Physical location of EEF1D_Gene
8: 144750726-144733041
A chromosome band present on 4q
4q31
A chromosome band present on 17q
17q21.31
8p
Chromosome 8 Short Arm
Chromosome 8p
Chromosome 8 Proximal Arm
Proximal (short) arm of chromosome 8
Xq13
A chromosome band present on Xq
Physical location of CRKL_Gene
22: 19596268-19632444
1p34.3-p32.1
A chromosome band present on 1p
A chromosome band present on 3q
3q26.1-q26.2
Left Lung Alveolus
Valve of Oval Foramen
Valve of the Oval Foramen
Tympanic Epithelium
Ovarian Cortex
The outer layer of the ovary, composed of cellular connective tissue which contains the ovarian follicles.
An ion channel with selective permeability for sodium.
Sodium Channel
Physical location of CYP17A1_Gene
10: 104587168-104580284
The major arterial trunk that carries oxygenated blood from the left ventricle into the ascending aorta behind the heart, the aortic arch, through the thorax as the descending aorta and through the abdomen as the abdominal aorta; it bifurcates into the left and right common iliac arteries.
Aorta
Aortic
ARTERY, AORTA
Physical location of GAGED3_Gene
X: 51945089-51951834
6: 18372750-18332392
Physical location of DEK_Gene
4q32
A chromosome band present on 4q
6q24-q25
A chromosome band present on 6q
Embryonic Atrium
8q
Distal (long) arm of chromosome 8
Chromosome 8 Long Arm
Chromosome 8 Distal Arm
Sylvian Cistern
Foot Digit Skin
1p36.11
A chromosome band present on 1p
Left Ventricle
The left lower chamber of the heart that receives blood from the left atrium and pumps it through the aorta to the body.
HEART, LEFT VENTRICLE
Internal Lateral Ligament of the Ankle
Internal Mammary Vein
Helix-Turn-Helix Motif
The first DNA-binding protein motif to be recognized. Originally identified in bacterial proteins and found in many DNA-binding proteins from both eukaryotes and prokaryotes. They are constructed from two alpha helices connected by a short extended chain of amino acids, which constitute the "turn." The two helices are held at a fixed angle, primarily through interactions between the two helices.
HTH DNA Binding Domain
Helix-Turn-Helix
The fourth of the seven cervical vertebrae.
C4 Vertebra
Morula
Border
Anatomic Border
The boundary of a surface or object.
Left Colon
COLON, LEFT
The portion of the large intestine that includes the descending and sigmoid colon.
Elbow Skin
Lamina Rara Interna
Embryonic Vein
Physical location of LMYC_Gene
1: 40036668-40034495
A triangular-shaped organ located under the diaphragm in the right hypochondrium. It is the largest internal organ of the body, weighting up to 2 kg. Metabolism and bile secretion are its main functions. It is composed of cells which have the ability to regenerate.
Body System, Hepatic
Hepatic Organ System
Organ System, Hepatic
Hepatic Body System
Gastrointestinal Tract, Liver
Liver
Epidermal
The epithelial portion of the skin (cutis). It consists of the following layers: stratum corneum (horny layer), stratum granulosum (granular layer), stratum spinosum (prickle cell layer), and stratum basale (basal cell layer).
Epidermis
A chromosome band present on 1p
1p36.12
2: 48756599-48871936
Physical location of ALF_Gene
5q32-q34
A chromosome band present on 5q
Basal Plate
Bronchial Epithelial Cell
C1 Vertebra
Atlas of the Vertebra
The first of the seven cervical vertebrae.
6q14.3-16.1
A chromosome band present on 6q
Bladder Urothelium
Bladder Transitional Epithelium
Bladder Transitional Cell Epithelium
Couinaud segment V, corresponding to the anterior segment of the right lobe of the liver, located inferiorly.
Couinaud Segment V
Right Anteroinferior Segment
Submandibular Ganglion
A chromosome band present on 4q
4q34
The cavity in the vertebrate body enclosed by the ribs between the diaphragm and the neck and containing the lungs and heart.
BODY CAVITY, THORACIC
Thoracic Cavity
13q32
A chromosome band present on 13q.
Gastric Vein
Physical location of JTB_Gene
1: 150763524-150759820
Superior Temporal Sulcus
Lower Eyelid
Physical location of BID_Gene
22: 16631812-16591460
Origin of Replication
ORI
Replication Origin
ARS
Autonomously Replicating Sequence
A DNA sequence necessary and sufficient for initiation of DNA replication.
13q33
A chromosome band present on 13q
4q35
A chromosome band present on 4q
Anterior Descending Coronary Artery
A left coronary artery branch that descends on the anterior portion of the heart through the anterior interventricular groove.
CORONARY ARTERY, ANTERIOR DESCENDING
Sinus Venarum
Right Lung
The 3-lobed lung located on the right side of the body.
LUNG, RIGHT
A network of membrane components where vesicles from the endoplasmic reticulum fuse with the Golgi apparatus.
Cis-Golgi Network
CGN
Nervi Vascularis
3: 129777627-129773542
Physical location of GR6_Gene
The univalent hydrocarbon radical -NH2.
Amine Group
Amine
2: 113259202-113247724
Physical location of IL1A_Gene
Liver Acinus Zone 2
Zone 2 of Lliver Acinus
Zone 2 of the Lliver Acinus
Zone 2
A chromosome band present on 13q
13q34
21p
Proximal (short) arm of chromosome 21
Chromosome 21 Proximal Arm
Chromosome 21 Short Arm
Septum Secundum
Chromosome Territory
Chromosomal Territory
The physical volume occupied by a specific chromosome in the interphase nucleus. The territories from distinct chromosomes do not appear to overlap, preventing an intermingling of the decondensed chromatin. Relative to a nuclear landmark (e.g. nucleolus), chromosome territories appear to differ from cell to cell.
Neural Crest-Derived Cell
A chromosome band present on 10q.
10q23.2
6p12
A chromosome band present on 6p
Zygomaticus Minor
SRCR-Interspersed Domain
SID Domain
22q12.2
A chromosome band present on 22q
Common Cardinal Vein
Zone 3
Zone 3 of Lliver Acinus
Zone 3 of the Lliver Acinus
Liver Acinus Zone 3
21q
Distal (long) arm of chromosome 21
Chromosome 21 Distal Arm
Chromosome 21 Long Arm
Crown of the Tooth
Corona Dentis
Crown of Tooth
Tooth Crown
Crown
The portion of the tooth covered by enamel.
Bipartite DNA binding domain containing a homeo domain and a leucine zipper.
HD-ZIP Domain
Pulp Chamber
The central cavity of the tooth crown that is occupied by the dental pulp.
Gland of Krause
An epithelial cell lining the endometrial cavity, located in the uterus. These cells proliferate and respond to the cyclic variations of estrogen and progesterone. They synthesize or transport and secrete substances essential for survival and development of the embryo/fetus and associated extraembryonic membranes.
Endometrial Glandular Cell
Triangular Part of the Inferior Frontal Gyrus
A chromosome band present on 7q
7q31.3-q32
22: 40851379-40847001
Physical location of CYP2D6_Gene
10q25.3
A chromosome band present on 10q
7: 75087684-75085765
Physical location of CCL24_Gene
Peripheral (Post-Thymic) T-Lymphocyte and Natural Killer Cell
Peripheral (Post-Thymic) T-Lymphocyte and NK-Cell
17: 29606411-29608335
Physical location of CCL2_Gene
2: 219909177-219899999
Physical location of ABCB6_Gene
Peripheral Epidermotropic T-Lymphocyte
Juxtamedullary Nephron
The Estrogen Binding Domain is an all-helical ligand-binding domain within its nuclear hormone receptor. Steroid hormones, such as estrogen, and their receptors regulate eukaryotic gene expression, affecting target cell proliferation and differentiation. Hormone-receptor complexes recognize discrete DNA sequences upstream of transcription start sites. (NCI)
Estrogen Binding Domain
Physical location of CSPG6_Gene
10: 112317474-112354382
Proximal (short) arm of chromosome 10
Chromosome 10 Short Arm
Chromosome 10 Proximal Arm
10p
lymph vessel
VESSEL, LYMPHATIC
Vessel, Lymph
A tubule that carries lymph throughout the body.
Lymphatic Vessel
Filiform Papilla
Spinal Meninx
Connective tissue membranes that surround and support the spinal cord and cauda equina. They are continuous with cranial meninges, which surround and support the brain.
Spinal Meninges
Physical location of CDC42_Gene
1: 22124488-22164742
Bone Surface
Physical location of FABP1_Gene
2: 88266840-88261772
GLAND, CIRCUMANAL
Circumanal Gland
A large apocrine gland located in the area surrounding the anal orifice.
New blood vessels formed by solid tumors.
Neovasculature
Tumor-Associated Vasculature
Rathke Pouch Epithelium
Cricoid Cartilage
10q25.1
A chromosome band present on 10q
Left Hypochondriac Region
Bulboglandular
10q
Distal (long) arm of chromosome 10
Chromosome 10 Distal Arm
Chromosome 10 Long Arm
Renal Tubule Epithelium
Lymph Node Afferent Vessel
15: 97010288-97319134
Physical location of IGF1R_Gene
Lymphoid Follicle
Connective Tissue Component of the Peripheral Nerve
4: 185770852-185684064
Physical location of IRF2_Gene
Tonsil Part
Seminal Vesicle
GLAND, SEMINAL VESICLE
Seminal Vesicles
Seminal Sacs
One of the two paired glands in the male genitourinary system, posterior to the bladder and superior to the prostate gland, that produces fructose-rich seminal fluid which is a component of semen. These glands join the ipsilateral ductus deferens to form the ejaculatory duct.
9: 91203730-91055664
Physical location of AUH_Gene
Plantar Foot Interosseus Muscle
7: 115758790-115795181
Physical location of CAV1_Gene
A stem cell obtained from the umbilical cord.
Umbilical Cord Blood Stem Cell
Multiple Cancer Sites
More than one cancer site.
10: 50417078-50336715
Physical location of ERCC6_Gene
Gluteus Medius
Grooves or clefts in the surface of a tooth.
Dental Fissure
Physical location of CYP1A1_Gene
15: 72804930-72798943
Brachialis
Small Intestinal Serosal Surface
The thin outermost layer of loose connective tissue covering the outer surface of the small intestine. It is derived from the peritoneum.
A cell that enables a T-lymphocyte to recognize an antigen by engulfing the antigen, breaking down the antigen into smaller fragments which bind to MHC molecules on the surface of the antigen presenting cell. The T-lymphocyte can now recognize and bind with the MHC-linked antigen.
APC
Accessory Cell
Antigen-Presenting Cells
Antigen Processing Cell
Antigen Presenting Cell
Antigen Presenting Cells
Immunological Accessory Cell
Antigen-Presenting Cell
Inferior Mesenteric Artery
11: 46364683-46363244
Physical location of CHRM4_Gene
Adrenals
suprarenal gland
Adrenal Glands
Adrenal Gland
A flattened, roughly triangular body resting upon the upper end of each kidney; it is one of the ductless glands furnishing internal secretions (epinephrine and norepinephrine from the medulla and steroid hormones from the cortex).
Retro-Orbital Region
6q21
A chromosome band present on 6q
Macromolecular Structure
Any very large complex molecule including, proteins, nucleic acids and carbohydrates, especially refering to the particular arrangement of its component atoms and groups.
Molecular Structure
Head and Neck, Salivary Glands
OTHER AND UNSPECIFIED MAJOR SALIVARY GLANDS
Salivary Glands
An exocrine gland that secretes saliva. Salivary glands are mostly located in and around the oral cavity.
Salivary Gland
Dorsalis Pedis Artery Branch
Immunoglobulin-Like Domain
The major histocompatibility complex (MHC) molecules are made of 2 chains, alpha and beta. In class I, the alpha chain is composed of 3 extracellular domains, a transmembrane region and a cytoplasmic tail while the beta chain is of a single extracellular domain. In class II, both the alpha and the beta chains are composed of 2 extracellular domains, a transmembrane region and a cytoplasmic tail. The immunoglobulin (Ig) constant chain domains and a single extracellular domain in each type of MHC chains are homologous and approximately one hundred amino acids long, and include a conserved intra-domain disulfide bond. Members of the immunoglobulin superfamily are found in hundreds of proteins of different functions, e.g., antibodies, the giant muscle kinase titin and receptor tyrosine kinases. Immunoglobulin-like domains may be involved in protein-protein and protein-ligand interactions. (InterPro IPR007110)
Immunoglobulin Domain
X: 48401210-48408967
Physical location of GATA1_Gene
A cell forming a cup for the outer hair cell of the Organ of Corti. The supporting cell sends out a narrow filament that angles towards the base of the cochlea. The structure is such that the supporting cell touches the outer hair cell only at the top and bottom.
Outer Supporting Cell
Outer Phalangeal Cell
13q11-q12
A chromosome band present on 13q
Toe Joint
Genital System, Female, Uterus
Uterine
Utero
Womb
A hollow, thick-walled, muscular organ located within the pelvic cavity of a woman. Within the uterus the fertilized egg implants and the fetus develops during pregnancy.
Uterus
A lymphoid cell of follicular center cell origin that has an irregularly shaped nucleus with clumped chromatin, absent nucleoli, and one or more clefts in the nuclear membrane.
Small Cleaved Cell
Small Cleaved Follicle Center Cell
Common Canaliculus
The portion of the spinal cord located in the sacral region.
SPINAL CORD, SACRAL
Sacral Spinal Cord
6q22
A chromosome band present on 6q
Ovarian Interstitial Cells
Theca Cells
Theca Cell
The connective tissue cells of the ovarian follicle. (MeSH)
The tissue of the esophageal wall. It is composed of mucosa, a muscular coat, and a serosal surface.
ESOPHAGUS
Esophageal Tissue
Physical location of IL12A_Gene
3: 161189331-161196508
A vein that represents a continuation of the angular vein and lies behind the facial artery.
Anterior Facial Vein
Part of the chromosome bands present on the short (p) arm of chromosome 12.
12p13.11
Hippocampus
Hippocampal
BRAIN, HIPPOCAMPUS
A curved gray matter structure of the temporal lobe lying on the floor of the lateral ventricle of the brain.
A chromosome band present on 7p
7p13-p11.1
Choroid Plexus Epithelium of the Fourth Ventricle
Physical location of HCK_Gene
20: 30103718-30153320
Physical location of GPRK2L_Gene
4: 3002549-3079479
Endocrine System Part
6p25.3
A chromosome band present on 6p
Physical location of RASD1_Gene
17: 17340432-17338480
A chromosome band present on 22q
22q11.1-q11.2
The X or Y chromosome in human beings that determines the sex of an individual. Females have two X chromosomes in diploid cells; males have an X and a Y chromosome. The sex chromosomes comprise the 23rd chromosome pair in a human karyotype.
Sex Chromosome
19: 45483036-45431556
Physical location of AKT2_Gene
Perivitelline Space
6q23
A chromosome band present on 6q.
Anterior Olfactory Lobule
Ovarian Granulosa Cell
A cuboidal cell derived from a spindle-shaped granulosa cell precursor. Initially, ovarian granulosa cells create a single layer surrounding an oocyte. The oocyte and its single layer of ovarian granulosa cells make up a primary follicle. Proliferation of the ovarian granulosa cells leads to multiple cell layers surrounding the oocyte and maturation into a secondary follicle. The granulosa cells extend cytoplasmic processes to form gestational gap-junction-like unions with the plasma membrane of the oocyte. The continued growth of the ovarian granulosa cells takes the oocyte to the Graafian follicle stage. Once ovulation occurs, the granulosa cells become part of the corpus luteum. A major function of an ovarian granulosa cell is hormone production and secretion.
Stratum Disjunctum
Parathyroid Gland Clear Cell
A large cell of the parathyroid gland. It has abundant clear cytoplasm packed with glycogen and a basal nucleus.
Teres Muscle
Xp11.22-p11.21
A chromosome band present on Xp
A cell that is antigenically distinct from other lymphocytes.
Lymphocytes, Allogeneic
Allogeneic Lymphocyte
Anterior Surface of the Vagina
The surface of the vagina that is in relation with the bladder and the urethra.
Bone marrow in the humerus bone.
Bone Marrow, Humerus
Trachea Lamina Propria
Pontine Base
Basis Pontis
Base of Pons
Physical location of NFIX_Gene
19: 12996776-13066584
Thyroid Gland Follicle
Thoracic Aorta
A gland from which secretions reach a free surface of the body by ducts.
Apocrine
Apocrine Gland
Exocrine Gland
A chromosome band present on 6q
6q24
Secondary Protein Structure
Secondary Structure
The level of protein structure in which regular hydrogen-bond interactions within contiguous stretches of polypeptide chain give rise to alpha helices, beta strands (which align to form beta sheets) or other types of coils. This is the first folding level of protein conformation. (MeSH)
Nasal Cavity Respiratory Epithelium
Facial Nerve Ganglion
Genicular Ganglia
Genicular Ganglion
Geniculate Ganglion
Renal Papilla
6q16.3-q21
A chromosomal band present on 6q.
Any covalent linkage between two polymers or between two different regions of the same polymer.
Cross Link
Cross Linked
The skin or integument surrounding the trunk of the body.
Skin of Trunk
Skin of the Trunk
A chromosome band present on 8q
8q22.1
Straight Artery
Straight Artery of the Endometrium
Biceps Femoris
MUSCLE, BICEPS FEMORIS
A muscle in the back of the thigh. Its action involves the knee flexion and hip extension.
Radial Vein of the Upper Extremity
Primordium of Liver
Primordium of the Liver
Physical location of BCL2L2_Gene
14: 22845866-22850798
Membrane of the Smooth Endoplasmic Reticulum
A lipid bilayer enclosing the portion of the endoplasmic reticulum that is free of ribosomes.
Calcium Channel
An ion channel with selective permeability to calcium.
19: 50651307-50605864
Physical location of ASE-1_Gene
Physical location of CRYPTIC_Gene
2: 131073278-131066531
Autonomic Nervous System Part
Foramen Magnum
A large orifice in the occipital bone through which the spinal cord enters the cranial cavity.
Distal 1/3 of the Common Bile Duct
Bone Marrow Stem Cell Committed to the Megakaryocytic Lineage
A primitive undifferentiated cell which can undergo division and can give rise to one of the early megakaryocytes.
6: 167506668-167523040
Physical location of CCR6_Gene
Inferior Suprarenal Artery
The upper one third of esophagus in which the muscle layer is composed of muscle cells of the striated type.
Upper Third of Esophagus
ESOPHAGUS, UPPER THIRD
Upper Third of the Esophagus
Any long raised border or margin of a bone or tooth or membrane.
Ridge
Nerve Tissue, Neuroepithelial Tissue, and Nerve Sheaths
The basic components of the nervous system. They contain neurons, supporting cells, and neuroepithelial cells.
14: 22658314-22656355
Physical location of CEBPE_Gene
The smooth muscle tissue present in the tunica media which is the middle layer of the aortic wall.
Aorta Smooth Muscle Tissue
A vein that returns blood to the heart from the adrenal gland. The right adrenal vein empties directly into the inferior vena cava and the left adrenal vein empties into the left renal vein.
Suprarenal Vein
Adrenal Vein
One of the two photoreceptor cell types in the vertebrate retina. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision. (MeSH)
Retinal Cone
Cone
Cones (Retina)
Cones
Cones (Eye)
Photoreceptors, Cone
Cone Cell
The designation for each member of the eighteenth largest human autosomal chromosome pair. Chromosome 18 spans about 76 million base pairs and represents about 2.5% of the total DNA in normal diploid cells.
Chromosome 18
The fleshy part of the face bounded by the eyes, nose, ear, and jaw line.
Cheek
A chromosome band present on 4q
4q31.1-q31.2
19: 50863342-50877557
Physical location of GIPR_Gene
The designation for each member of the sixteenth largest human autosomal chromosome pair. Chromosome 16 spans about 90 million base pairs and represents just under 3% of the total DNA in normal diploid cells.
Chromosome 16
Tissue consisting of mucous or serous secreting epithelial tissue, connective tissue, blood vessels, nerves and lymphatic tissue.
Salivary Gland Tissue
GLAND, SALIVARY
Class V Intermediate Filament
Type V IF
Type V Intermediate Filament
An intermediate filament located in the nucleus of a cell, which plays a role in the maintenance of nuclear structure.
Nuclear Lamin
9: 34681274-34679567
Physical location of CCL19_Gene
Totipotent Neuroepithelial Stem Cell
A relatively undifferentiated cell that retains the ability to divide into any type of nerve cell.
Carboxy
Carboxyl
The univalent radical -COOH; present in and characteristic of organic acids.
Carboxyl Group
The bony arch formed by the collarbones and shoulder blades.
Shoulder Girdle
Parietal Lobe of the Brain
Parietal Lobe
One of the lobes of the cerebral hemisphere located superiorly to the occipital lobe and posteriorly to the frontal lobe. Cognition and visuospatial processing are its main functions.
Neuroglia
nerve cement
Kolliker's reticulum
Neuroglial Cells
Glial Cells
Non-neuronal cell
Glia
Glial Cell
The non-neuronal cells of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu, participate in the blood-brain and blood-retina barriers, form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. Neuroglia have high-affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitters, but their role in signaling (as in many other functions) is unclear. (MeSH)
Subcellular respiratory organelles containing catalase and hydrogen peroxide-producing flavin oxidases among its enzymatic constituents, which carry out an essentially oxidative type of metabolism
Microbody
Peroxisome
Dura
Dura Mater
The outermost, toughest, and most fibrous of the three membranes (meninges) that surround and protect the brain and spinal cord.
Chromosome 17
The designation for each member of the seventeenth largest human autosomal chromosome pair. Chromosome 17 spans more than 81 million base pairs and represents between 2.5 and 3% of the total DNA in normal diploid cells.
3q13.3-q21
A chromosome band present on 3q
1: 236396793-236398565
Physical location of CHRM3_Gene
VEIN, BRACHIAL
Brachial Vein
Deep vein of the upper arm that forms at the junction of the radial and ulnar veins and ends at the inferior border of the teres major.
A lipid bilayer enclosing the part of the endoplasmic reticulum that has ribosomes located on the cytoplasmic-facing membrane.
Membrane of the Rough Endoplasmic Reticulum
Physical location of CD58_Gene
1: 116825645-116769199
Organ Capsule
Trachea Smooth Muscle Tissue
The two organs situated in the throat on either side of the narrow passage from the mouth to the pharynx. They are composed of lymphoid tissues.
Tonsils
Tonsil
A chromosome band present on 9p
9p22.2
Superior Internal Articular Artery
3: 39346219-39351077
Physical location of CCR8_Gene
renal fascia
Perirenal Fascia
Gerota's Capsule
Gerota's Fascia
Renal Capsule
Chief Cells
Epithelial cells that line the basal half of the gastric glands. They synthesize and secrete pepsinogen, a precursor of the enzyme pepsin. (MeSH)
Chief Cell
Inferior Pancreatico-Duodenal Vein
Cementoenamel Junction
The area of a tooth where the enamel of the crown and the cementum of the root(s) are joined.
Cymba Conchae
9: 21375396-21374254
Physical location of IFNA2_Gene
C2H2 Zinc Finger
One of three structural motifs observed in DNA binding domains of zinc proteins. Domains in DNA- and RNA-binding proteins that contain amino acids which are folded into a single structural unit around a zinc atom that links two cysteines and two histidines. Each finger is postulated to recognize a specific sequence of about five nucleotide pairs. Originally identified in the TFIIIA transcription factor, it is also known as the C2H2 zinc finger.
17: 37181645-37164390
Physical location of JUP_Gene
Chromosome 19
The designation for each member of the nineteenth largest human autosomal chromosome pair. Chromosome 19 spans more than 63 million base pairs and represents between 2 and 2.5% of the total DNA in normal diploid cells.
Bone Trabeculae
Anastomosing, needle-like bony structures which create a meshwork of spaces filled with bone marrow.
17: 26665217-26654919
Physical location of EVI2B_Gene
Neurula
Superficial Lymphatic Vessel
10q25-qter
A chromosome band present on 10q
A chromosome band present on 15q
15q22-qter
A chromosome band present on 4p
4p15.32
Anterior Cerebral Artery
ACA
Anterior Cerebral Arteries
One of the two arteries arising from the internal carotid artery and being part of the Circle of Willis. Both left and right anterior cerebral arteries are connected by the anterior communicating artery.
Physical location of CRSP2_Gene
X: 40351037-40263812
Bronchus Basement Membrane
A depression or fissure where vessels or nerves or ducts enter a bodily organ.
Hilum
Xq27.3
A chromosome band present on Xq.
Endocrine Cell of the Gastrointestinal System
Cells found throughout the lining of the gastrointestinal tract that contain regulatory peptide hormones and/or biogenic amines. There are at least 15 different types of endocrine cells of the gut. Some take up amine precursors and have been called APUD cells. However, most endocrine cells of the gut apparently have endodermal rather than neuroectodermal origin, so the relationship with APUD cells is not clear. (MeSH)
Endocrine Cells of Gut
Endocrine Cell of Gut
Endocrine Cells, Gastrointestinal
2q22.2-q23.3
A chromosome band present on 2q
Deep Femoral Artery Branch
The narrow passage from the mouth to the cavity at the back of the mouth.
Throat
10q26.2
A chromosome band present on 10q
GLAND, SALIVARY, MUCOUS
Salivary glands that produce and secrete a saliva made up exclusively of mucous.
Mucous Salivary Gland
7: 45734052-45725189
Physical location of IGFBP3_Gene
Elbow Joint
A type of hinge joint located between the forearm and upper arm.
Elbow
Chamber of the Eye
Physical location of CENPF_Gene
1: 211175452-211226309
SCN
Suprachiasmatic Nucleus
A tear-shaped dense area of cells in the hypothalamus, which is responsible for regulating circadian rhythms.
17q22-q23.2
A chromosome band present on 17q
Fetal Gastrointestinal Tract
Orbiculus Ciliaris
Cricotracheal Ligament
Primitive Stem Cell with Some Degree of Commitment to the Erythroid Lineage
Pars Anterior Pituitary Gland
Anterior Lobe of Pituitary
Glands, Anterior Pituitary
Gland, Anterior Pituitary
Pituitary Gland, Anterior
Pituitary Anterior Lobe
Anterior Lobe of Pituitary Gland
Anterior Lobe of the Pituitary Gland
Anterior Pituitary Gland
Adenohypophysis
The glandular or anterior lobe of the pituitary gland which secretes several hormones.
Occipito-Frontalis Muscle
Xq11.1
A chromosome band present on Xq
A chromosome band present on 2p
2p16.3
Dorsal Horn of the Spinal Cord
S4 Vertebra
7: 72292964-72295149
Physical location of FZD9_Gene
22: 24285500-24444470
Physical location of ADRBK2_Gene
Dorsal Metacarpal Artery
Sarcoplasm
The cytoplasm of striated muscle fibre.
Physical location of ATM_Gene
11: 107599053-107741971
Cerebral Fornix
Ductal Cells
Ductal Cell
A stratified columnar epithelial cell that surrounds a lumen in a gland such as the breast, pancreas or prostate. These cells are uniform in appearance and have uniformly sized and shaped nuclei.
Ductal Epithelial Cell
20: 3014058-3011186
Physical location of AVP_Gene
Skin Fluid and Secretion
Skin-Fluids, Secretions
Skin Fluids and Secretions
Secretions of the skin.
Skin Fluid or Secretion
11: 65443304-65445607
Physical location of DRAP1_Gene
It refers to amino acid residues that can be the target for protein kinase C phosphorylation. (NCI)
PKC Phosphorylation Site
The anterior aspect of the tympanum.
Anterior Wall of the Tympanum
A chromosome band present on 4p.
4p15.31
11: 113351120-113366245
Physical location of HTR3_Gene
Ureteric Bud
Metanephric Diverticulum
Hand Digit Skin
Internal Calcanean Artery
4p16.3-p16.1
A chromosome band present on 4p
A chromosome band present on 22q
22q12.3-q13.1
Genomic Feature Physical Location
The physical location on a specified chromosome of a feature or area of interest expressed as a base pair position.
Cerebral Sulcus
Undersurface of the Temporal Lobe
Nail Fold
Splenic Flexure of Colon
Left Colic Flexure
Splenic Flexure
The bend at the junction of the transverse and descending colon.
One of the two types of grooves found in a right-handed double helix, running between the sugar phosphate backbones of each strand.
Major Groove
Specialized depressions on the cell surface involved in receptor-mediated endocytosis; the visible proteinaceous layer on the cytosolic side of the depression provides the coated appearance.
Coated Pit
1: 110165499-110184397
Physical location of CSF1_Gene
A chromosome band present on 7q
7q21.3
Alveolus
Any of the terminal sacs in the lungs through which gas exchange takes place with the pulmonary capillary blood.
Bronchial Alveolus
Pulmonary Alveolus
Alveoli
Thyroarytenoid Muscle
Endocrine Testis
Physical location of COMT_Gene
22: 18303863-18331084
Burr Hole
Part of the ejaculated fluid. It contains secretions from the seminal vesicles, Cowper's gland, and prostate gland.
Seminal Fluid
2q36.1
A chromosome band present on 2q
Villus
Urinary Bladder Trigone
Trigone of Bladder
Trigone of the Bladder
BLADDER, TRIGONE
The triangular area in the bladder mucosa that is formed by the two ureteral orifices and the urethral orifice.
Bladder Trigone
Upper Eyelid
A microtubule that has a C-shape in cross-section.
C-Microtubule
Splenic Hilar Lymph Node
6: 7672009-7826724
Physical location of BMP6_Gene
Physical location of ITGAM_Gene
16: 31178812-31251691
7: 127644257-127626283
Physical location of IMPDH1_Gene
Gingival Margin
The crest of the gingiva surrounding a tooth.
Perisinusoidal Space
The area between hepatocytes and the epithelium lining the sinusoids of the liver. The space contains reticular fibers and microvilli from the hepatocytes. Proteins produced by the hepatocytes are transferred to the blood via the perisinusoidal space as blood fluids easily move through the epithelium and microvilli.
Space of Disse
Nasolacrimal Groove
8q21.3-q22
A chromosome band present on 8q
Extensor Digitorum Longus
The bottom most subdivision of either the right or left lung.
Lower Lobe of the Lung
Lung Lower Lobe
Lower Lobe, Lung
7q21.1
A chromosome band present on 7q
Intracranial Arteries
Intracranial Artery
Arteries which have their origins within the intracranial cavity.
Embryonic Disc
Physical location of EPHA1_Gene
7: 142622822-142605042
Sensory Hair
Cell found within the glomerular lobules of mammalian kidney. Mesangial cells serve as structural supports, may regulate blood flow, are phagocytic and may act as accessory cells, presenting antigen in immune responses.
Mesangial Cell
15: 50584606-50585400
Physical location of EEF1B1_Gene
Pericallosal Artery
A chromosome band present on 10q
10q23.2-q23.3
A group of three types of polymeric protein structures that impart shape to a cell and are involved in cellular motility, organelle localization and vesicular targeting.
Filament
Cytoskeletal Filament
Cytoskeleton Filament
Blood vessels forming villous structures in the third, fourth, and lateral ventricles of the brain.
Choroid Plexus
BRAIN, CHOROID PLEXUS
Chromosome 11
The designation for each member of the eleventh largest human autosomal chromosome pair. Chromosome 11 spans about 134.5 million base pairs and represents between 4 and 4.5% of the total DNA in normal diploid cells.
15q22-q24
A chromosome band present on 15q
Keratin Filament
A class of intermediate filaments that form a network within epithelial cells and anchor to desmosomes, thus imparting tensile strength to the tissue
2: 74031790-74058434
Physical location of ACTG2_Gene
Microtubule
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. (from LocusLink)
Micro-tubule
Micro Tubule
A chromosome band present on 2q
2q36.3
CD8-Positive Lymphocytes
CD8+ T Lymphocytes
CD8 Lymphocytes
CD8 Cell
CD8-Positive T-Lymphocytes
CD8+ T-Lymphocyte
CD8+ T Lymphocyte
T8 Cells
CELLS.CD8
CD8-Positive T-Lymphocyte
A subpopulation of regulatory T-lymphocytes involved in MHC Class I-restricted interactions. They include both cytotoxic T-lymphocytes and suppressor T-lymphocytes. (MeSH)
T8 Lymphocytes
Physical location of GLTSCR2_Gene
19: 52940620-52952127
Chromosome 14 Physical Location
Polychromatophilic Erythroblast
Bipartite DNA binding domain containing a basic region directly interacting with DNA, and a leucine zipper mediating dimerization through contacts with a protein partner.
bZIP Domain
Basic Leucine Zipper
Columella
Modiolus
Cells of the lymphoid series that can react with antigen to produce specific cell products called antibodies. (MeSH)
Antibody-Producing Cell
Immunoglobulin-Producing Cells
Antibody Producing Cell
Antibody-Producing Cells
Visual System
Visual Pathway
The designation for each member of the tenth largest human autosomal chromosome pair. Chromosome 10 spans about 135 million base pairs and represents between 4 and 4.5% of the total DNA in normal diploid cells.
Chromosome 10
4p14-q21
A chromosome band present on 4p
Physical location of ITGB3_Gene
17: 42686207-42745076
Vein Endothelium
Subsegmental Bronchus of Left Lung
A part the bronchial tree of the left lung, an air passage arising from any segmental bronchus of the left lung and passing to the naturally delimited part of lung segment (subsegment), where it further subdivides into smaller passages.
Velum Interpositum Cistern
Connective tissue mainly composed of parallel collagenous fibers leaving little room for embedded fibroblasts. This tissue has high tensile strength, but elasticity and flexibility are limited. Examples are tendons, ligaments and the fasciae and aponeuroses of muscles.
Regular Dense Connective Tissue
Cerebrospinal Fluid
CSF
FLUID, CEREBROSPINAL
Cerebral Spinal Fluid
The fluid that is contained within the brain ventricles, the subarachnoid space and the central canal of the spinal cord.
Usually a protein, it is produced in the granular endoplasmic reticulum and the Golgi complex. Morphologically, it is defined as a membrane-bound particle.
Secretory Granule
4: 77301829-77299452
Physical location of CXCL10_Gene
Tectum Mesencephali
A chromosome band present on 17q
17q11-q21
6p12-p11.1
A chromosome band present on 6p
12: 47152715-47153110
Physical location of ANP32D_Gene
The designation for each member of the thirteenth largest human autosomal chromosome pair. Chromosome 13 spans about 113 million base pairs and represents between 3.5 and 4% of the total DNA in normal diploid cells.
Chromosome 13
Cell Junction
Cell junction is the specialized focal contact between cell-cell or cell-matrix in all tissues. Cell junctions have various functions either communication, anchoring or organization. There are specific protein associated with subtype of cell junctions and most of the junctions are too small to be resolved by light microscope.
Dentate Gyrus
A serrated strip of gray matter under the medial border of the hippocampus and in its depths. It is an archicortex which develops along the edge of the hippocampal fissure and which consists of molecular, granular, and polymorphic layers.
A chromosome band present on 9p
9p22.3
Lingual Tonsil
Nasal Prominence
The area that is internal to the inner mitochondrial membrane.
Mitochondrial Matrix
3: 47798410-47602391
Physical location of SMARCC1_Gene
Epithelial Cell
Epithelial Cells
One of the cells that cover the surface of the body and line its cavities.
Surgically-Created Resection Cavity
Intrasurgical Resection Cavity
Resection Cavity
SCRC
Surgically-Created Cystic Resection Cavity
The space that is left after the surgical removal of a body part or tumor.
The fifth layer of the cerebral cortex, composed of the largest pyramidal cells (Martinotti's cells and Betz's cells), and traversed by a layer of horizontally arranged fibers.
Ganglionic Layer of the Cerebral Cortex
Large Pyramidal Cell Layer
Internal Pyramidal Cell Layer
Inner Pyramidal Cell Layer
Ganglionic Layer
2p24.1
A chromosome band present on 2p
The designation for each member of the twelfth largest human autosomal chromosome pair. Chromosome 12 spans about 143 million base pairs and represents between 4 and 4.5% of the total DNA in normal diploid cells.
Chromosome 12
Slow-Twitch Motor Unit
The part of the breast which is in the center.
Central Portion of the Breast
Central Portion of Breast
Cytotrophoblastic Shell
Ion Channel
A transmembrane pore that presents a hydrophilic channel for ions to cross a lipid bilayer down their electrochemical gradients. Some degree of ion specificity is usually observed and typically a million ions per second may flow. Channels may be permanently open, like the potassium leak channel or they may be voltage gated, like the sodium channel or ligand gated like the acetylcholine receptor.
Maxillary Artery
Muscle of the Coccyx
Endocrine cells found in the pyloric gland mucosa (antral mucosa) of the stomach and responsible for the secretion of gastrin. (MeSH)
G-Cell
Gastrin Cell
Gastrin Secreting Cell
Gastrin Cells
G Cell
G Cells
1: 201384254-201317962
Physical location of GAC1_Gene
Auditory Cortex
The area in the cerebral cortex that receives and processes auditory input.
C5 Vertebra
The fifth of the seven cervical vertebrae.
Hair Follicle Isthmus
The amino acid residing in the last position of a protein or peptide.
C-Terminal Amino Acid
C-Terminal
Carboxy-Terminal Amino Acid
Epiglottic Cartilage
Cuneate Nucleus
The designation for each member of the fifteenth largest human autosomal chromosome pair. Chromosome 15 spans about 106 million base pairs and represents between 3 and 3.5% of the total DNA in normal diploid cells.
Chromosome 15
Nucleated red blood cell
Erythrocytes, Nucleated
Erythroblasts
NUCLEATED RBCS
Nucleated red cell
Erythroblast
An immature, nucleated erythrocyte occupying the stage of erythropoiesis that follows formation of erythroid progenitor cells and precedes formation of reticulocytes.
Ventral Thalamus
Physical location of BTG2_Gene
1: 200006321-200010387
The mouth, teeth, jaws, pharynx, and related structures as they relate to mastication, deglutition, and speech. (MeSH)
Stomatognathic System
BONE, FIBULA
Fibula
The small, lateral calf bone extending from the knee to the ankle.
spermoblast
spermid
Spermatids
Spermatoblasts
Spermatid
Male germ cells derived from spermatocytes and developing into spermatozoa. (MeSH)
Sternocostal Joint
Neuroendocrine Tissue
Physical location of KNG_Gene
3: 187917822-187944445
Quadrigeminal Cistern
Brain White Matter
A protein region consisting of a hydrophilic surface and a hydrophobic core.
Globular Region
Testis
Either of the paired male reproductive glands that produce the male germ cells and the male hormones.
Testicles
Testicle
Testes
Genital System, Male, Testis
Highly pigmented epithelium covering the posterior surface of the iris.
Posterior Pigment Epithelium
Canal
A bodily passage or tube lined with epithelial cells and conveying a secretion or other substance.
Right Adrenal Gland
Keratinocyte
Keratinocytes
Epidermal cells which synthesize keratin and undergo characteristic changes as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell.
Physical location of JAK2_Gene
9: 4975245-5117995
Physical location of EREG_Gene
4: 75595895-75619512
Chromosome 14
The designation for each member of the fourteenth largest human autosomal chromosome pair. Chromosome 14 spans about 105 million base pairs and represents between 3 and 3.5% of the total DNA in normal diploid cells.
Parasympathetic Nervous System
Cisterna of the Rough Endoplasmic Reticulum
One of the flattened membrane-bound regions of the rough endoplasmic reticulum.
Common Bile Duct
Ductus Communis Choledochus
Bile ducts are passageways that carry bile. Two major bile ducts come together into a "trunk"-the common bile duct which empties into the upper part of the small intestine (the part next to the stomach).
Heart Part
A chromosome band present on 1p
1p32-q12
7q36.1
A chromosome band present on 7q
Coeliac Artery
Coeliac Axis
Coeliac Trunk
Common Femoral Artery
15: 77024475-77001162
Physical location of CTSH_Gene
Genu of the Corpus Callosum
Immune System Part
A chromosome band present on 16p
16p13.13-p13.12
Ubiquitous supportive tissue adjacent to epithelium and around smooth and striated muscle cells. This tissue contains intrinsic macromolecular components such as collagen, laminin, and sulfated proteoglycans. As seen by light microscopy one of its subdivisions is the basal (basement) lamina.
Basement Membrane
Left Pulmonary Vein
1q12-q23
A chromosome band present on 1q
The organs involved with detecting and processing auditory information, including the pinna, external auditory canal, ear drum, middle ear, and inner ear (including the cochlear organ).
Auditory System
Physical location of AIM2_Gene
1: 155859720-155845348
Third Pharyngeal Pouch
Lower Respiratory System
Anterior Auricular Vein
A vein that drains the auricle and acoustic meatus of the external ear.
A chromosome band present on 3p
3p23-p21
4q25
A chromosome band present on 4q
The tendon that connects the heel bone to the calf muscles at the back of the lower leg.
Calcanean Tendon
TENDON, CALCANEAL
Achilles Tendon
Physical location of CDKN2A_Gene
9: 21984490-21957752
Chromosome 9 Short Arm
Chromosome 9 Proximal Arm
Proximal (short) arm of chromosome 9
9p
11: 6237542-6249932
Physical location of CCKBR_Gene
Physical location of ADCY9_Gene
16: 4105460-3954907
Internuncial Neuron
Intercalated Neurons
Interneurons
A general term for any neurons which are not motor or sensory. Interneuron may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions. (from MeSH)
Connector Neuron
Intercalated Neuron
Interneuron
Internuncial Cell
Intercalary Neuron
Central Artery
A branch of the maxillary artery that is found in the gingiva, premolars, and molars.
Alveolar Artery
Hemidesmosome
Half desmosomes that occur on the basal surface of the stratum basalis of stratified squamous epithelium.
Proximal (short) arm of chromosome 22
Chromosome 22 Proximal Arm
Chromosome 22 Short Arm
22p
9q21.11
A chromosome band present on 9q.
Sternum
The long, flat bone connecting with the cartilages of the first seven ribs and the clavicle.
BONE, STERNUM
breastbone
Sterna
Inferior Vena Cava
Brush Cell
A cell characterized by the presence of a tuft of blunt, squat microvilli (120-140/cell) on the cell surface. The microvilli contain filaments that stretch into the underlying cytoplasm. It has a distinctive pear shape with a wide base and a narrow microvillus apex. This cell is distinct from the unipolar brush cell found in the cerebellar cortex.
Tentorium Cerebelli
4q22
A chromosome band present on 4q
Parathyroid Gland Epithelial Tissue
The part of the lower portion of the mediastinum that is located behind the pericardium.
Posterior Mediastinum
MEDIASTINUM, POSTERIOR
Lymphoblast
An immature lymphocyte that has enlarged in response to antigenic stimulation.
lymphoblastic
UBC Domain
The 16-kD UBC domain contains a conserved UBC motif and a conserved cysteine that accepts activated ubiquitin from E1 enzyme to form a thiol ester. Basic residues at the UBC domain N-terminus may be involved in E1 binding. UBC/E2 enzymes catalyze ubiquitination of target proteins with or without E3 'N-end' recognizing proteins. E2s can be classified on the basis of UBC structure. Poor at transferring ubiquitin to proteins on their own, Class I proteins comprise simply the UBC domain and probably require an E3 to ubiquitinate short-lived abnormal proteins prior to degradation. Class II enzymes contain different acidic C-terminal extensions of the UBC domain that appear to involve cellular localization or to mediate interaction with protein substrates for ubiquitination that results in protein modification but not degradation. Class III E2s have N-terminal extensions, but their function is unknown. (NCI)
Ubiquitin-Conjugating Domain
17q21.1-q21.2
Part of the chromosome bands present on the long (q) arm of chromosome 17.
Embryonic Ventricle
Chromosome 22 Long Arm
Chromosome 22 Distal Arm
Distal (long) arm of chromosome 22
22q
A chromosome band present on 22q.
22q13.31
Alveolar Wall
The alveolar structure that contains alveolar cells type I and II and macrophages.
Upper Clivus
Parieto-Occipital Fissure
Tibial Nerve
One of two major branches of the sciatic nerve. It innervates the muscles of the posterior aspect of the lower limb, the muscles of the plantar aspect of the foot, as well as the skin on the posterior aspect of the leg and on the sole of the foot.
NERVE, TIBIAL
Mons Pubis
17q21.1-q21.3
A chromosome band present on 17q
A chromosome band present on 9p
9p13-p12
8q24.11-q24.13
A chromosome band present on 8q
The fifth set of paired nerves of the face that emerge from the brain steam. These nerves have sensory and motor functions in the face, oral cavity, and nasal cavity.
NERVE, TRIGEMINAL
Nervus Trigeminus
Fifth Cranial Nerve
Cranial Nerve V
Trigeminal Nerve
Fissure of Sylvius
Sylvian Fissure
Fab
Antigen Binding Fragment
Immunoglobulin, F(ab) Fragment
Fab Fragment
Part of an immunoglobulin antibody that binds a specific antigen and consists of both a light chain and part of a heavy chain. By comparison, natural antibodies consist of two heavy and two light chains. An FAB (fragment antibody) offers the advantages of smaller size and lower cross-reactivity compared to the complete antibody. (NCI04)
Intra-Abdominal Lymph Node
Intra-abdominal Lymph Nodes
Any lymph node within the abdomen.
17: 24940735-24924620
Physical location of GIT1_Gene
Renal Tubule Basement Membrane
Physical location of HPCA_Gene
1: 33021191-33029340
22q13.33
A chromosome band present on 22q
3: 38055700-38139233
Physical location of DLEC1_Gene
Internal Carotid Artery
Ilio-Lumbar Vein
Iliolumbar Vein
Lateral Surface of the Liver
Right Surface of the Liver
Lateral Surface of Liver
Right Surface of Liver
Arch
A structure with a curved or bowlike outline.
A chromosome band present on 8q
8q21.13
6: 151653623-151770023
Physical location of AKAP12_Gene
9: 2005342-2183620
Physical location of SMARCA2_Gene
Physical location of AGT_Gene
1: 227156602-227145020
Epiphysis of the Bone
Growth Plate
Epiphyseal Plate
EPIPHYSIS
Junction, Bone-Cartilage
The round end of the long bones.
A late precursor of a granulocyte in which the nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature polymorphonuclear neutrophil.
Band Cell
A short columnar epithelial cell that has deposited enamel and has lost organic material and water. It deposits calcium and phosphorus into the enamel matrix. The maturation-stage ameloblast produces and secretes small amounts of proteins.
Maturation-Stage Ameloblast
Intestinal Smooth Muscle Tissue
4q21
A chromosome band present on 4q
1p13.3-p13.1
A chromosome band present on 1p
Physical location of BNIP3L_Gene
8: 26296440-26326561
Physical location of GPT_Gene
8: 145700231-145703357
Trinucleotide Repeat
Euchromatin. The parts of chromosomes that, during interphase, are uncoiled dispersed threads and not stained by ordinary dyes; metabolically active, in contrast to the inert heterochromatin.
Euchromatin
Physical location of CCNE2_Gene
8: 95976660-95961628
Neural Plate
Neuroectoderm
Ectomesenchyme
The dorsal surface of the early vertebrate embryo that gives rise to the nervous system.
Thyroepiglottic Ligament
The spindle pole body (SPB) is the microtubule organizing center (MTOC) in the yeast Saccharomyces that plays a pivotal role in such diverse processes as mitosis, budding, and mating. (from Cell. 1997;89:1077-86)
Spindle Pole Body
Upper Gingiva
10p15-p14
A chromosome band present on 10p
9q
Distal (long) arm of chromosome 9
Chromosome 9 Long Arm
Chromosome 9 Distal Arm
Nephron
The functional units of the kidney, consisting of the glomerulus and the attached tubule. (MeSH)
Uriniferous Tube
Intercalated Duct
8q21.12
A chromosome band present on 8q
Sulcus Limitans
A myofilament composed of actin and tropomyosin.
Thin Filament
Physical location of GRB2_Gene
17: 70913384-70825753
Opening of the Antrum
Embryonic Structure or System
Embryologic Structure or System
Body tissue, region, surface, cavity, fluid, organ, or collection of organs present in, or associated with, an embryo.
Vena Cava Endothelium
4: 89735485-89784497
Physical location of CEB1_Gene
Body of the Nail
Extraocular Muscle
MUSCLE, EXTRAOCULAR
Oculomotor Muscle
A group of six muscles that are responsible for moving the eye.
Middle Occipital Convolution
Ectocervical Os
Exocervical Os
A chromosome band present on 14q
14q24.3-q31
A cell derived from a promyelocyte. It differentiates into a metamyelocyte. It has a diameter of 10-18 micrometer, and an oval or round nucleus with finely granulated chromatin.
Myelocyte
14q23-q24
A chromosome band present on 14q
Posterior Commissure
Outer Segment of the Photoreceptor Cell
LH Cell
A luteinizing hormone secreting cell found in the anterior pituitary gland.
Monocytes / Macrophages / APC
Macrophages
Macrophage
Furrows, with pouchlike recesses at the lower end, separating the rectal columns.
Anal Sinus
Internal Jugular Vein
A continuation of the sigmoid sinus of the dura mater; joins the subclavian vein to form the brachiocephalic vein.
LYMPH NODE, RENAL
A lymph node located in the hilar area of the kidney or the fat surrounding the kidney.
Renal Lymph Node
Right Lobe of the Liver
Wall of body of uterus is composed of three layers: endometrium, myometrium, and perimetrium. Endometrium is the inner mucosal layer lining and is covered with columnar epithelium and tubular glands. Myometrium is a thick, muscular layer, consisting largely of bundles of smooth muscle fibers arranged in longitudinal, circular, and spiral patterns, and interlaced with connective tissue. Perimetrium is the outer layer composed of the peritoneal layer of the broad ligament that covers the body of the uterus and part of the cervix.
Wall of Body of Uterus
2p16.1
A chromosome band present on 2p
Embryonic Eye
A chromosome band present on 9q
9q31.1
4p12
A chromosome band present on 4p
An organ behind the lower part of the stomach that is the shape of a fish and about the size of a hand. It is a compound gland composed of both exocrine and endocrine tissues. The endocrine pancreas makes insulin so that the body can use glucose (sugar) for energy. The exocrine pancreas makes enzymes that help the body digest food. Spread all over the pancreas are areas called the Islets of Langerhans. The cells in these areas each have a special purpose. The alpha cells make glucagon, which raises the level of glucose in the blood; the beta cells make insulin; the delta cells make somatostatin. There are also PP cells and D1 cells, about which little is known.
Pancreas
Gastrointestinal Tract, Pancreas
Bone marrow in the rib.
Bone Marrow, Rib
Physical location of LTA_Gene
6: 31648072-31650077
9q21-q22
A chromosome band present on 9q
Neuropil
A dense intricate feltwork of interwoven fine glial processes, fibrils, synaptic terminals, axons, and dendrites interspersed among the nerve cells in the gray matter of the central nervous system. (MeSH)
HAIR SHAFT
The segment of the hair that projects above the skin surface.
Shaft of the Hair
Trancus Arteriosus
Integumentary System Part
Muller Tubercle
Sinus Tubercle
Lower Extremity Part
The skin or integument surrounding the leg.
Leg Skin
Cervical Curve
Internal Iliac Artery Branch
Extremity Part
Periosteal Cell
A cell of the loose cellular inner layer of the periosteal tissue in the intramembranous ossification of bone
The mucosal membranes located on the inside of the cheek, in the buccal cavity.
MUCOSA, BUCCAL
Buccal Mucosa
Anterior Caudate Vein
A vein that it is part of the deep intracranial venous system.
A branch of the abdominal aorta that supplies blood to the intestines.
Mesenteric Artery
ARTERY, MESENTERIC
Intraparietal Sulcus
Subclavian Vein
Transverse Rectal Fold
Hyaline cartilaginous joint between the ribs and costal cartilage.
Costochondral Junction
Costochondral Junction, Rib
Costochondral Joint
Anterior Median Fissure of Spinal Cord
A fissure in the midline of the anterior surface of the spinal cord.
Anterior Median Fissure of the Spinal Cord
Base Pair
9q31.3
A chromosome band present on 9q.
Zygomaticus
Zygomaticus Muscle
Physical location of EGFL6_Gene
X: 13347398-13411351
A chromosome band present on Xq
Xq21.33-q23
Orthodox Configuration of the Mitochondrion
Physical location of DDX6_Gene
11: 118167082-118125623
11: 102100868-102088540
Physical location of MMP8_Gene
Any tiny hole admitting passage of a liquid (fluid or gas).
Pore
Gonad
A reproductive system organ that produces and releases either sperm (testis) or eggs (ovary).
Gonads
Gonadal
Sphenoid Sinus
Sinus, Sphenoid
Either of the paired paranasal sinuses, located in the anterior part of the body of the sphenoid bone and communicating with the superior meatus of the nasal cavity on the same side.
Amniotic Cavity
The fluid-filled space within the amnion that contains the developing fetus.
11: 69922292-69960338
Physical location of EMS1_Gene
Found near the apical surface of cells in simple epithelia. Forms a sealing "gasket" around the cell by the fusion of adjacent cell membranes which encircle the apical cell surface like a belt or fence. Prevents fluid moving through the intercellular gap and the lateral diffusion of intrinsic membrane proteins between apical and basolateral domains of the plasma membrane as well as occludes the movement of solute molecules between cells. Various proteins components of this junction have been identified, but how they are linked to form the ultrastructure of the junction is not known.
Zonula Occludens
Occluding Junction
Tight Junction
1q31
A chromosome band present on 1q
Distal Phalanx of Foot
4q31.2
A chromosome band present on 4q
Renal Tubule
The anatomical segment of the kidney that is comprised of both the nephron and associated collecting tubules. These tubules or tubes contains fluid that has been filtered through the glomerulus.
A short elastic band that unites the epiglottis to the upper border of the hyoid bone.
Hyoepiglottic Ligament
The border, edge, or margin of an organ or a part.
Anatomic Rim
4q28
A chromosome band present on 4q
2: 165303867-165174840
Physical location of GRB14_Gene
Superficial Cervical Lymph Node
Esophageal Epithelium
A portion of the peritoneal cavity formed by the greater and lesser omentum. It is located posteriorly to the stomach and extends into the greater omentum.
Omental Bursa
Zygomatic Buttress
The portion of the maxillary jaw bone and other facial bones that form the most lateral mid face skeletal structure known as the cheekbone.
4q31.1
A chromosome band present on 4q
Internal Oblique Muscle
Ascending Oblique Muscle
Vertebral Artery Branch
17q24.3
A chromosome band present on 17q
Physical location of FHL2_Gene
2: 105513478-105435803
Pilar Sheath
Tragus
A chromosome band present on 4p
4p16
PROSTATE GLAND, LATERAL LOBE
Lateral Lobes of Human Prostate
The prostate gland lobe that is located on the lateral side of the organ.
Lateral Lobe of the Prostate
Physical location of CCNB2_Gene
15: 57184612-57204536
EGF-Like Domain
A sequence of about thirty to forty amino-acid residues long found in the sequence of epidermal growth factor (EGF) has been shown to be present, in a conserved form, in a large number of other, mostly animal proteins. The list of proteins currently known to contain one or more copies of an EGF-like pattern is large and varied. The functional significance of EGF domains in what appear to be unrelated proteins is not yet clear. However, a common feature is that these repeats are found in the extracellular domain of membrane-bound proteins or in proteins known to be secreted (exception: prostaglandin G/H synthase). The EGF domain includes six cysteine residues which have been shown (in EGF) to be involved in disulfide bonds. The main structure is a two-stranded beta-sheet followed by a loop to a C-terminal short two-stranded sheet. Subdomains between the conserved cysteines vary in length. (InterPro IPR006209)
7: 45701327-45706499
Physical location of IGFBP1_Gene
A chromosome band present on 17p
17p12-p11.2
17q24.2
A chromosome band present on 17q
Hand Interosseous Muscle
Calf
The posterior aspect of the lower extremity that extends from the knee to the foot.
Scalp Vascular Plexus
A chromosome band present on 4p
4p13
Physical location of C-KIT_Gene
4: 55365089-55447783
Utricle
Lymphoid Blood-Forming Cell
Lymphoid Blood-Forming Cells
A lymphoid blood-forming cell is a hematopoietic stem cell that is a precursor for a T lymphocyte or B lymphocyte.
Occipital Bone
A chromosome band present on 1q
1q32
Splenic Trabecular Vein
Spleen Trabecular Vein
Phalanx of the Hand
Phalanges of Hand
Phalanx of Finger
Phalanx of Hand
Hand Phalanx
A bone of the hand.
Bone of Finger
2: 197489931-197454606
Physical location of GTF3C3_Gene
Posterior Cruciate Ligament
Cleidocephalic
Subsegmental Lymph Node Station
The lymph nodes around the subsegmental bronchi.
Subsegmental Lymph Node
Duct of Gartner
A sheet or band of fibrous connective tissue enveloping, separating, or binding together muscles, organs, and other soft structures of the body.
Fascia
4p14
A chromosome band present on 4p
7: 86987215-86777599
Physical location of ABCB1_Gene
COLON, SIGMOID
Sigmoid Colon
The portion of the colon that connects to the descending colon above and the rectum below.
A columnar-shaped cell found in the epithelium of the lobular bronchiole. Each cell contains 200-300 cilia 5-8 mm long. The cilia are part of the mucociliary system, which extends through the tracheobronchial tree and into the respiratory bronchioles. This system protects the respiratory surface from dirt and airborne infection and represents the principal mechanism of defense in the respiratory tract. The cilia beat in unison (about 1,000 strokes per minute) and in a wave-like fashion, thereby propelling mucus and entrapped foreign material toward the oropharynx for expectoration or swallowing.
Ciliated Bronchial Epithelial Cell
Waist
The abdominal circumference at the navel.
Inferior Parathyroid Gland
17q11-qter
A chromosome band present on 17q
Retroperitoneal Cavity
Retroperitoneal Space
Retroperitoneum
The back of the abdomen where the kidneys lie and the great blood vessels run.
Muscle Cell
A connective tissue cell with the ability to convert chemical energy into mechanical energy via a contractile apparatus. As part of the contractile apparatus, the proteins actin and myosin form parallel myofilaments. The interaction of actin and myosin mediates muscle cell contraction in response to stimulation of the excitable cell membrane.
Muscle Cells
Myocyte
Physical location of LGALS8_Gene
1: 233007606-233039037
Bone Marrow-Homing Plasma Cell
A mature white blood cell, differentiated in the bone marrow, activated to preferentially migrate to the bone marrow.
Ventrolateral Nucleus of the Thalamus
Respiratory System Part
Ring Finger Motif
Ring-Type Zinc Finger Domain
Ring Finger
Ring Finger Domain
RING finger domains are defined by the consensus sequence CX2CX(9-39)CX(1-3)HX(2-3)C/HX2CX(4-48)CX2C with the Cys and His representing zinc binding residues. RING fingers are further divided into RING-HC and RING-H2, depending on whether a Cys or His occupies the fifth coordination site. While RING fingers are structurally diverse, all contain two interleaved Zn2+ binding sites. Binding of the Cbl RING domain to the E2 protein, UbcH7, occurs between a groove within the RING domain and two loops in the E2 fold of UbcH7. Van der Waals interactions involving hydrophobic residues in both the E2 and RING domains support the Cbl-UbcH7 binding, though this is not universal as the RING-E2 pair of Rad18p and Rad6p/Ubc2p interact by hydrogen bonding of polar residues.
The RING finger is a specialized type of Zn-finger consisting of 40 to 60 residues that binds two atoms of zinc, and is involved in mediating protein-protein interactions. The RING domain mediates the interaction with the appropriate E2 enzyme. Unlike HECT E3 enzymes that form a thiol-ester with ubiquitin, RING fingers likely mediate ubiquitination by facilitating the direct transfer of ubiquitin from E2 enzyme to lysine residues on the target substrate. (NCI)
A vesicle formed by the fusion of the plasma membrane, which captures extracellular fluids and solutes during pinocytosis.
Pinocytotic Vesicle
Primary Bronchial Bud
The semipermeable membrane that encloses the cytoplasm of a cell.
Cell Membrane
Plasmalemma
Plasma Membrane
11q24-q25
A chromosome band present on 11q
3: 3127031-3086421
Physical location of IL5RA_Gene
Pluripotent Bone Marrow Stem Cell
Enterochromaffin Cell
Enterochromaffin
Enterochromaffin Cells
EC Cell
A group of basal granular cells of the gut whose granules stain readily with silver and chromium salts. The cells secrete serotonin, substance P, and enkephalins. (MeSH)
TOOTH
Tooth Tissue
Teeth
Odontogenic Tissue
The tissue that forms the tooth. It consists of the dental pulp, dentin, enamel, cementum, odontogenic epithelium, and periodontium.
Medial Rectus Muscle
The portion of the parotid gland parenchyma lying deep to the facial nerve.
Parotid Gland Deep Lobe
Spinal Cord Tract
Tracts of Spinal Cord
Ascending and Descending Tracts of Spinal Cord
Spinal Cord Tracts
Physical location of CBL_Gene
11: 118582196-118675922
Hair Papilla
11q24-q24
A chromosome band present on 11q
Eosinophilic Leukocyte
Eosinophilic Granulocyte
Eosinophils
Eosinocyte
Granular leukocytes with a nucleus that usually has two lobes connected by a slender thread of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and stainable by eosin.
Blood Eosinophil
Eosinophil
Marrow Eosinophil
Acidophilic Leukocyte
Mucosa-Associated Lymphoid Tissue
Lymphoid Tissue, Mucosa-associated
MALT
Lymphoid tissue located beneath the mucosal epithelia of those mucosal surfaces that have contact with the external environment, such as the respiratory, digestive, and urinary systems. MALT consists of a collection of predominantly small lymphocytes, fewer larger, transformed lymphocytes, and plasma cells. It protects the body from pathogens that enter via the mucosa. MALT gives rise to a distinctive type of B-cell lymphoma that usually follows an indolent clinical course.
Postgerminal Center Memory B-Lymphocyte
A branch of the middle cerebral artery that supplies blood to the anterior part of the temporal lobe.
Anterior Temporal Artery
Nasal Cavity Epithelium
Superior Infratentorial Cistern
9: 14303719-14077373
Physical location of NFIB_Gene
Autophagic Vacuole
An organelle with a double membrane that sequesters proteins and other organelles which may be targeted for degradation.
Autophagosome
Fovea Centralis
Area consisting of a small depression in the retina containing only cones and where vision is most acute.
Fovea
hepatobiliary
The liver, gallbladder, and associated ducts, considered collectively.
Hepatobiliary System
Piloid Astrocyte
Henle's Loop
Loop of Henle
Laryngotracheal Tube
Left Portion of the Diaphragm
Levator Ani
19: 10375271-10362809
Physical location of CDC37_Gene
Crossed Pyramidal Tract
21: 33524101-33558697
Physical location of IFNAR2_Gene
Physical location of CDK3_Gene
17: 71509014-71513251
Midcortical Nephron
Intermediate Nephron
Heterochromatin found in the nucleus near the interior face of the inner nuclear membrane.
Marginal Chromatin
Electron-Dense Plasma Membrane Layer
The hydrophilic portions of the plasma membrane as seen during transmission electron microscopy. This electron density is caused by abundant staining by heavy metal-containing dyes.
Acromion
The upper distal process of the scapula.
Epicondyle
A bone prominence to which ligaments and tendons of the joints are attached.
Physical location of GPT2_Gene
16: 45475809-45522699
Great Saphenous Vein
Long Saphenous Vein
Subcostal Artery
Physical location of SMARCA1_Gene
X: 128382976-128306013
Wall of Prostatic Duct
Wall of Human Prostatic Duct
The lumen of the glandular structures of a crypt.
Crypt Glandular Lumen
5p15.33
A chromosome band present on 5p
4: 68253212-68301377
Physical location of BRDG1_Gene
Infraclavicular
Infraclavicular Region
The region below the clavicle.
Urethra Transitional Cell Epithelium
Urethra Transitional Epithelium
Urethra Urothelium
Epithelium composed of a single layer of cells that are taller than they are wide. They are found lining the stomach, intestine, uterus and gall bladder. Simple columnar epithelium is efficient at secretion and absorption.
Simple Columnar Epithelium
1: 26328627-26331156
Physical location of CD52_Gene
A chromosome band present on 2q
2q37.1
Perivascular Space
The space between a blood vessel and the pia mater.
Pericyte
Slender, contractile, mesenchymal-like cells found in close association with capillary walls. They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells. (MeSH)
Adventitial Cell
Pericytes
Perivascular Cell
Rouget Cells
Pericapillary Cell
A chromosome band present on 5q
5q11.2-q13.2
Isthmus
Hair
The filamentous outgrowth of the epidermis.
15: 64466679-64570936
Physical location of MAP2K1_Gene
Primary Lymph Sac
Olfactory Epithelium
An epithelium located in the roof, superior conchae, and septum of the nasal cavity. It is formed by ciliated olfactory receptor cells, supporting cells and basal cells. Olfactory glands in the epithelium produce and secrete mucus which forms a layer over the epithelium. The cilia of the receptor cells protrude into the mucous layer where molecular reception with odors occurs and sensory transduction begins.
Physical location of CXCL11_Gene
4: 77314415-77312021
A chromosome band present on 5q
5q23.3-q31.1
17: 65110015-56824974
Physical location of BCAS3_Gene
Retrosacral Lymph Node
LYMPH NODE, RETROSACRAL
A lymph node located in the retrosacral region.
5q31.1-q33.1
A chromosome band present on 5q
Physical location of H2AX_Gene
11: 118471387-118469797
Temporal Muscle
Pulp Horn
The portion of the pulp chamber that extends towards a cusp.
Orbital Sulcus
Superficial Palmar Arch
Membrane Part
Lamina Densa
Basal Lamina
A layer of extracellular matrix found beneath epithelial tissues. It is secreted by epithelial cells and comprised of proteoglycans, laminin and type IV collagen.
A term referring to the brain area that is supplied by both the right and the left internal carotid arteries and their arterial branches.
Intracranial Anterior Circulation
Nasal Cavity
Accessory Sinuses
An air-filled cavity adjacent to the nasal cavity lined by a mucous membrane and located in the bones of the skull. There are four paranasal sinuses on each side of the face: ethmoid, frontal, maxillary, and sphenoid sinus.
Nasal Sinuses
Paranasal Sinus
Nasal cavity/Paranasal sinuses
Nasal cavity/Paranasal
Sinuses, Paranasal
Accessory sinus
Sinuses, Nasal
Nasal And Sinuses
Paranasal Sinuses
Nasal Sinus
Modified epidermal cells located in the stratum basale. They are found mostly in areas where sensory perception is acute, such as the fingertips. Merkel cells are closely associated with an expanded terminal bulb of an afferent myelinated nerve fiber. (MeSH)
Merkel's Receptor
Merkel Cells
Merkel Cell
Inferior Occipital Convolution
Intradural Extramedullary Spinal Canal Space
Hematopoietic and Lymphoid Tissue
HEMOLYMPHORETICULAR TISSUE
The intercalated cell is an epithelial cell of the renal collecting tubule that is specialized for H+ and HCO3 transport. These cells exist in two types, [alpha] and [beta]. The [alpha] cell secretes H+ into the lumen by an apical H+ ATPase and a basolateral Cl:HCO3. The [beta] cell secretes HCO3- into the lumen by an apical Cl:HCO3 and a basolateral H+ ATPase.
Dark Cell
Intercalated Cells
Intercalated Cell
Pontine Branch
Spleen Germinal Center
Splenic Germinal Center
The area within the membrane of an endosomal compartment.
Lumen of the Endosome
12: 53099272-53075315
Physical location of ITGA5_Gene
Pancreatic Exocrine Secretion
Secretion from the pancreas that contains digestive enzymes.
Exocrine Pancreas Secretion
3: 142979741-143020030
Physical location of GPRK7_Gene
Sphenoparietal Sinus
19: 47079107-47103444
Physical location of ARHGEF1_Gene
Tear
A fluid containing oils, mucin, and proteins, which is secreted by the lacrimal gland and cleans and lubricates the eye.
A chromosome band present on 1p
1p21-p13.3
A chromosome band present on 10q
10q11.21
Eyelid Muscle
INTESTINE
Intestinal Wall Tissue
The tissue that forms the wall of the small and large intestine. It consists of mucosa, submucosa, muscular coat, and serosal surface.
Peritoneal Mesothelial Cell
Cortical
Cortex
The outer layer of the cerebrum composed of neurons and unmyelinated nerve fibers. It is responsible for memory, attention, consciousness and other higher levels of mental function.
Cerebral Cortex
Physical location of CRSP6_Gene
11: 93157096-93186102
White matter pathway, flanked by nuclear masses, consisting of both afferent and efferent fibers projecting between the cerebral cortex and the brainstem. It consists of three distinct parts: the anterior limb, posterior limb, and genu. (MeSH)
Internal Capsule
Sesamoid Bone
Otolymph
Physical location of EDN2_Gene
1: 41619390-41613540
A white blood cell derived from bone marrow precursors which lack any T cell markers. It can give rise to either thymic cortical and medullary progeny, or medullary progeny alone.
Thymic B-Lymphocyte
The dorsal area between the base of the neck and the sacrum.
Back
Bile Juice
Bile
Fluid composed of waste products, bile acids, salts, cholesterol, and electrolytes. It is secreted by the liver parenchyma and stored in the gallbladder.
Lumbosacral Plexus
Relatively undifferentiated cells of the same lineage (family type) that retain the ability to divide throughout postnatal life to reproduce themselves and to give rise to other more specialized types of cells to take the place of those that die or are lost. (MeSH)
Stem Cells
Mother Cells
Progenitor Cells
Stem Cell
Auricle
Nerve of Pharyngeal Arch
Nerve of the Pharyngeal Arch
5: 112118469-112209533
Physical location of APC_Gene
Lymph node located in the bronchi.
LYMPH NODE, BRONCHIAL
Bronchial Lymph Node
Nuclear Lamina
The nuclear lamina is a proteinaceous filamentous meshwork of lamin proteins interacting with integral proteins of the inner nuclear membrane, including emerin, and is thought to play a role in nuclear stability, chromatin structure, and gene expression. Lamins are highly conserved in evolution and members of the intermediate filament protein family. Mammalian lamins are classified into two major types, A and B, with two subspecies of each: lamins A and C for the A type and B1 and B2 for the B type. Lamins A and C arise from one gene by alternative splicing. Pre-lamin A contains a carboxyl CAAX box that can be modified by farnesylation. During mitosis, the lamina meshwork is reversibly disassembled in parallel with phosphorylation of the lamins.
Connective tissue cells of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere.
Stromal Cell
Stromal Cells
Radial Artery of the Upper Extremity
Physical location of LATS1_Gene
6: 150131506-150023744
Inferior Mesenteric Vein
Chromosome 22
The designation for each member of the smallest human autosomal chromosome pair. Chromosome 22 spans about 49 million base pairs and represents between 1.5 and 2% of the total DNA in normal diploid cells.
endocrine pancreas cell
islets of Langerhans cell
Islet Cell
A pancreatic cell that produces and secretes hormones such as insulin and glucagon.
The body system or organ class that pertains to a medical history.
Medical History Body System or Organ Class
MHBODSYS
The slender tubular part of the hypophysial diverticulum; the stalk of Rathke's pocket.
Hypophysial Duct
Bucconeural Duct
Craniopharyngeal Duct
Semen
The thick, whitish secretion of the male reproductive organs. It is composed of spermatozoa in their nutrient plasma, secretions from the prostate, seminal vesicles, and various other glands, epithelial cells, and minor constituents.
Seminal Plasma
A secretory cell that discharges its product without loss of cytoplasm.
Eccrine Cell
Anterior Choroidal Artery
An artery, which originates in either the internal carotid artery or the middle cerebral artery, that delivers blood to the choroid plexus.
Renal Tubular Epithelial Cell
Physical location of CUL2_Gene
10: 35419300-35338814
A chromosome band present on 14q
14q24-q31
Parametrium
The subserous connective tissue of the pelvic floor of the supracervical portion of the uterus. The parametrium extends laterally between the layers of the broad ligament.
Peroneal Nerve
Any one of the three (common, deep, and superficial) peroneal nerves.
Nerve, Fibular
NERVE, PERONEAL
Inner Phalangeal Cell
A tall, slender cell extending from the basilar membrane to the free surface of the organ of Corti. Each cell surrounds an inner hair cell.
Inner Supporting Cell
Umbilical Blood
bHLH Domain
The bHLH domain is a bipartite DNA-binding domain containing a basic region upstream of an amphipathic helix-loop-helix region. The basic region interacts with DNA and the HLH motif mediates protein dimerization.
Chromosome 21
The designation for each member of the second smallest human autosomal chromosome pair. Chromosome 21 spans around 47 million nucleotides and represents about 1.5% of the total DNA in normal diploid cells.
An artery of the lower extremity that supplies blood to the anterior part of the leg and the foot.
Anterior Tibial Artery
Epitympanic Recess
Attic
17: 77261425-77279553
Physical location of HGS_Gene
Primordial Uteroplacental Circulation
Convolution of Broca
Left Inferior Frontal Convolution
BRCT domain was first identified in C-terminal domain of breast cancer associated protein and was found in many proteins that regulate the cellular response to DNA repair, where these domains act as multi-purpose protein-protein interaction modules. Crystallography study reveals that two ~95 amino acid BRCT repeats within the domain adopt similar structures that pack together in a head-to-tail arrangement. (NCI)
Breast Cancer Carboxy-Terminal Domain
BRCT Domain
Visual Pathway
Chromosome 20
The designation for each member of the third smallest human autosomal chromosome pair. Chromosome 20 spans around 63 million base pairs and represents between 2 and 2.5% of the total DNA in normal diploid cells.
Physical location of BRD2_Gene
6: 33044415-33057059
Physical location of SMARCD1_Gene
12: 48765279-48780692
Lymph
A clear, transparent, sometimes faintly yellow and slightly opalescent fluid that is collected from the tissues throughout the body, flows in the lymphatic vessels (through the lymph nodes), and is eventually added to the venous blood circulation. Lymph consists of a clear liquid portion, varying numbers of white blood cells (chiefly lymphocytes), and a few red blood cells.
Reticuloendothelial System, Lymph
lymphatic fluid
Intestinal Serosal Surface
Lymph Nodes of Inguinal Region or Leg
Lymph Node of Inguinal Region or Leg
Nuclear Inner Membrane
The nuclear envelope has two membranes, each with a typical unit membrane in structure. They enclose a flattened sac and are connected at the nuclear pore sites. The inner nuclear membrane separates the perinuclear cistern of the endoplasmic reticulum from the nucleoplasm. It is attached to and supported by the lamina. A growing number of proteins that are specifically located to this membrane seem to participate in functionally organizing the nucleus. (NCI)
Inner Nuclear Membrane
4q31-q32
A chromosome band present on 4q
Vital Tooth
A tooth with functioning pulpal tissue.
Thoracic Ganglion
7q32-q36
A chromosome band present on 7q
Striated Muscle
Striated muscles are appendicular and axial muscles typically connected at either or both ends to the bony skeleton of the body. Striated muscle fibers contain a highly organized, contractile cytoskeletal apparatus with a striated microscopic appearance; muscle contraction is typically under voluntary control.
Striated Muscle Tissue
7: 54860934-55049240
Physical location of EGFR_Gene
Physical location of CYP1A2_Gene
15: 72828237-72835994
Pretracheal Space
Malleolus of the Fibula
External Malleolus
The bony prominence on the outside of the ankle formed by the distal end of the fibula.
A chromosome band present on 14q
14q21-q24
Fundus of the Stomach
The portion of the stomach that lies above the cardiac notch. It allows for the accumulation of gases produced by chemical digestion.
Fundus of Stomach
STOMACH, FUNDUS
Physical location of CREB5_Gene
7: 28112180-18632857
Physical location of CYP8B1_Gene
3: 42892637-42888688
Small Intestine
The section of the intestines between the pylorus and cecum. The small intestine is approximately 20 feet long and consists of the duodenum, the jejunum, and the ileum. Its main function is to absorb nutrients from food as the food is transported to the large intestine.
Small Bowel
Gastrointestinal Tract, Small Intestine
Acupuncture Point
acupoint
Fissure of Rolando
Mentum
Chin
The part of the face below the lower lip and including the protruding part of the lower jaw.
Physical location of HK2_Gene
2: 74971437-75032136
Stratified Squamous Epithelium
Epithelium consisting of multiple layers of cells that are flattened and more cuboidal toward the base. Its function is protection. Outer layers may be dead and hardened (keratinized) such as with skin or on top of wet, mucous surfaces such as the cornea
Physical location of CD3D_Gene
11: 117718669-117714999
17: 36057629-36037508
Physical location of SMARCE1_Gene
4: 84613484-84570794
Physical location of HPSE_Gene
Reticular Fiber
A site on a protein that is a target for enzymatic cleavage, where the residue on the amino terminal side of the cleavage site is a basic amino acid that is not adjacent to other basic amino acids.
Monobasic Proteolytic Cleavage Site
Physical location of ETV3_Gene
1: 153921250-153916049
A cell derived from stem cells in the bone marrow. It is a maturing T lymphocyte that expresses an alpha-beta antigen specific surface receptor (TCR) and the CD8 surface marker. These cells mature in the thymus.
Immature Peripheral Alpha/Beta Cell of Cytotoxic Type
X: 48416735-48439629
Physical location of HDAC6_Gene
A chamber formation in an organ.
Antrum
A mature T lymphocyte, found in the intestinal lining that differentiates from its precursor outside the thymus, most likely in an area of the gut identified as cryptopatch aggregates. This cell plays a key role in cell-mediated mucosal defense, the down-regulation of immune responses to harmless luminal antigens and in epithelial cell growth and repair.
Intraepithelial T-Lymphocyte of the Intestine
Cardia Gland
Simple columnar epithelial tissue of the small canals that transport prostatic secretions from the glandular tubules to the urethra.
Prostatic Duct Tissue
Right Anterosuperior Segment
Couinaud Segment VIII
Couinaud segment VIII, corresponding to the anterior segment of the right lobe of the liver, located superiorly.
Vertebral Bone
One of twenty-four bones that make up the vertebral column.
Vertebra
BONE, VERTEBRA
Postganglionic Autonomic Fiber
Nerve fibers which project from cell bodies of autonomic ganglia to synapses on target organs. (MeSH)
Autonomic Fibers, Postganglionic
postganglionic fiber
14q21-q22
A chromosome band present on 14q
Column of Bertini
Renal Column of Bertini
Cortical Column
Anterior Horn Cell
Motor neurons in the anterior (ventral) horn of the spinal cord which project to skeletal muscles. (MeSH)
Neurons, Anterior Horn
Anterior Horn Cells
Ventral Horn Cells
Ventral Horn Neurons
The part of the skeleton that includes the skull and spinal column and sternum and ribs.
Axial Skeleton
D17S250
A dinucleotide repeat on chromosome 17 that serves as a marker for microsatellite instability in colorectal cancers.
D17S250 Dinucleotide Repeat
Either of the incisors found in the upper jaw.
Upper Jaw Incisor
Maxillary Central Incisor
Limb Bud
Y: 9897925-9900718
Physical location of TSPY_Gene
5: 159276318-159332129
Physical location of ADRA1B_Gene
External Carotid Artery Branch
6: 46386637-46392695
Physical location of CCR5_Gene
The basin-shaped skeletal structure that is formed by the sacrum and the ilium, ischium, and pubis of each side that supports the trunk and to which the lower extremities attach.
Pelvic Girdle
Physical location of FASTK_Gene
7: 150215599-150211356
The inner layer of the dura mater surrounding the brain. It is mostly fused with the outer layer, the endocranium that is adherent to the inner aspect of the cranial bones. These two layers form the dura mater. The latter covers and protects the brain and the spinal cord.
Meningeal Layer of the Dura Mater
A chromosome band present on 22q
22q11
Mental Artery
Transport Vesicle
A vesicle that can move between organelles to deliver molecules to target locations.
Odontogenic Ectomesenchyme
Pseudostratified Epithelium
A chromosome band present on 1q
1q43-q44
Physical location of FOSL2_Gene
2: 28527430-28549167
Pharyngeal Tonsil
Adenoid
A fold of lymphatic tissue covered by ciliated epithelium at the very back of the nose, in the roof of the nasopharynx.
Superficial Intracranial Venous System
Deep Palmar Artery
Muscle
Muscle Tissue
Tissue responsible for the body movements and the shape and size changes of interna organs. Muscle tissue is composed of specialized contractile cells. There are two types of muscle tissue recognized:striated and smooth muscle. The striated muscle tissue is further subdivided into skeletal, visceral striated, and cardiac muscle.
Ureter
The thick-walled tube that carries urine from each kidney to the bladder.
Organ of Special Sense Part
Middle Cranial Fossa
22q12
A chromosome band present on 22q
Subscapular Artery
5: 139706358-139692613
Physical location of DTR_Gene
Premolar
Bicuspid
TOOTH, BICUSPID
Premolar Tooth
Bicuspid Tooth
One of the two permanent teeth located in front of the molars and behind each cuspid. These teeth have two cusps (points) and are used to tear and grind food.
15q22.3-q23
A chromosome band present on 15q
Fourth Portion of Duodenum
Ascending Portion of Duodenum
Ascending Portion of the Duodenum
Fourth Portion of the Duodenum
EYE, RETINA
The tissue that constitutes the retina. It is composed of the following layers: ganglion cell layer, inner limiting membrane, inner nuclear layer, inner plexiform layer, layer of the ophthalmic nerve fibers, layer of the rods and cones, neural retina, outer limiting membrane, outer nuclear layer, outer plexiform layer, and retinal pigment epithelium.
Retina Layer
A chromosome band present on 7p
7p21-p15
A muscle located in the anterior aspect of the abdominal wall.
Anterior Abdominal Wall Muscle
4q11
A chromosome band present on 4q
Tissue comprised of specialized cells and intercellular matrix, aggregated according to genetically determined spatial relationships in order to carry out the functions of production and ovulation of oocytes and the production and secretion of hormones.
Ovarian Tissue
The death domain is a protein region, approximately 80 amino acids long, that is required for transmission of the cytotoxic signal of apoptosis and is present in the TNF receptor, FAS, and several downstream signaling molecules. Transmission of the apoptotic signal requires the functional interaction of proteins via the death domain.
Death Domain
Frontonasal Prominence
22q13
A chromosome band present on 22q
Dorsal Nasal Artery
A chromosome band present on 4q
4q12
A bean-shaped retroperitoneal organ situated below the diaphragm and posterior to the spleen.
Left Kidney
The body region composed of the vulva and vagina.
Vulvovaginal Region
Molar Tooth
A grinding tooth with a broad crown; located behind the premolars.
TOOTH, MOLAR
Pseudostratified Columnar Ciliated Epithelium
Epithelium composed of a single layer of cells, appearing as layered because the column-shaped cells vary in height so the nuclei are at different levels. The basal portions of all the cells are in contact with the basement membrane. It lines the respiratory system and the male reproductive tract. The cilia in the respiratory tract are motile, while the stereocilia in the male reproductive tract are immobile.
Esophageal Mucosa
Milk of Calcium
Densely calcified fluid, most often found radiographically in association with an obstruction.
2: 15682368-15721823
Physical location of DDX1_Gene
Thoracic Spine
T Spine
Those vertebrae of the thoracic region, T1-T12 in man.
Physical location of GLI_Gene
12: 56140201-56152312
19: 10311307-10305452
Physical location of ICAM3_Gene
The irregular network or rows of fine ribonucleoprotein granules or microfilaments forming most of the nucleolus.
Nucleolonema
Brunner's Glands
Small, flat, granular glands embedded in the submucous areolar tissue of the duodenum. (MeSH)
Brunner's Gland
Ganglia of the sympathetic nervous system including the paravertebral and the prevertebral ganglia. Among these are the sympathetic chain ganglia, the superior, middle, and inferior cervical ganglia, and the aorticorenal, celiac, and stellate ganglia. (MeSH)
Sympathetic Ganglion
16: 67236277-67290443
Physical location of CDH3_Gene
Chondrocyte
Polymorphic cells that form cartilage. (MeSH)
Chondrocytes
11q24.1
A chromosome band present on 11q.
Non-Granular Leukocyte
Leukocytes, Mononuclear
Non-Granular Leukocytes
Agranulocyte
Mononuclear Leukocyte
Leukocyte, Mononuclear
Mature lymphocytes andmonocytes transported by the blood to the body's extravascular space. They are morphologically distinguishable from mature granulocytic leukocytes by their large, non-lobed nuclei and lack of coarse, heavily stained cytoplasmic granules. (MeSH)
Irregular Bone
Hilar Area of the Left Lung
Type II Epithelial Receptor Cell
A light cell found in taste buds that has large amorphous areas of cytoplasmic matrix, scarce ribosomes and RER. Most are alpha-gustducin immunoreactive, some may be AbH immunoreactive and/or PGP 9.5 immunoreactive.
Type II Cell
A chromosome band present on 1p
1p36.33
Plantar Metatarsal Artery
Common Plantar Digital Artery
The layer of cells that lines the lumen of the aorta.
Aorta Endothelium
Kidney and Ureter
1: 238337576-238379089
Physical location of EXO1_Gene
Costal Arch
Splenocytes
A vague term that usually refers to the phagocytic cells (macrophages) of the spleen.
Splenocyte
Graft
Tissue or organ transplanted from a donor to a recipient.
Transplant
Retina Proper
A layer of nerve cells in the retina. Embryologically, it is part of the brain. Incoming light passes through nerve-fibres and intermediary nerve cells of the neural retina, before encountering the light-sensitive rods and cones at the interface between neural retina and the pigmented retinal epithelium.
Neural Retina
Septum Transversum
Physical location of GFI1B_Gene
9: 132883652-132896636
Tissue Part
Normal Tissue Part
Continuous Capillary
Posterior Wall of the Tympanum
Outer Plexiform Layer
Outer Plexiform Layer of the Retina
Respiratory Diverticulum
Physical location of BCL7A_Gene
12: 120921747-120962668
Physical location of KLK2_Gene
19: 56068501-56073673
The anterior aspect of the foramen magnum formed by the basilar part of the occipital bone.
Anterior Foramen Magnum
Tract, Biliary
Bile Tract
Biliary System
Biliary Tract
The system that transports bile from the hepatocytes in the liver to the small intestine. It is comprised of the intrahepatic bile ducts, hepatic ducts, common bile duct, cystic duct, and the gallbladder.
11q22.3
A chromosome band present on 11q
Physical location of CD80_Gene
3: 120761139-120725832
A medium sized round lymphocyte in the T-lymphocyte series, intermediate between the T-lymphoblast and the mature T-cell.
T-Prolymphocyte
Cervical Gland
An interstitial cell is a cell that is part of the connective and soft tissues.
Interstitial Cell
Central Nervous System Part
Superior Vena Cava Opening
The region of a multirooted tooth at which the root divides.
Furcation
Root Furcation
A flat, scale-like epithelial cell that lines the vaginal portion of cervix.
Ectocervical Squamous Cell
External Canal
Horizontal Canal
Mamillary Body
Leucine Zipper
Domains in DNA-binding proteins that contain amino acid sequences that show periodic arrays of leucine residues. These residues exist in an alpha-helical conformation, with the leucine side chains extending from one alpha helix interdigitating with those displayed from a similar alpha helix of a second polypeptide, facilitating dimerization.
Adipose Tissue
A specialized form of connective tissue consisting primarily of adipocytes (fat cells), surrounded by a meshwork of collagen fibers.
adipose
Body Fat
BODYFAT
Pronator Teres
Hypoglossal Nucleus
Nucleus of the Hypoglossal Nerve
Postgerminal Center Marginal Zone B-Lymphocyte
Highly conserved peptide motifs of the HMG-I(Y) proteins that preferentially bind to the AT-rich minor groove of DNA. The AT hook motif tethers and unwinds the minor groove of the DNA with very little specificity for the DNA sequence. The AT hook motif has a narrow DNA recognition surface that is devoid of hydrophobic amino acids and that does not significantly distort the B-form DNA structure.
Highly conserved peptide motifs of the HMG-I(Y) proteins that preferentially bind, in vivo and in vitro, to the narrow minor groove of stretches of AT-rich DNA. The AT Hook Motif tethers and unbends the minor groove of the DNA with very little specificity for the DNA sequence. The AT hook motif has a narrow DNA recognize surface which is devoid of hydrophobic amino acids and does not significantly distort the B-form DNA structure.
AT Hook Domain
ATH
AT Hook Motif
Parenchyma composed of seminiferous tubules embedded in loose connective interstitial tissue. The interstitial tissue contains clusters of testosterone-secreting Leydig cells, collagen and myoid cells.
Testicular Parenchyma
Testicular Tissue
Tibialis
Tibialis Muscle
Foramen Secundum
One of the nodes that lie along the course of a lymphatic vessel between a primary melanoma site and a recognized node field. (from Medscape)
Interval Lymph Node
VEIN, SAPHENA
Saphenous Vein
One of two (Greater, Small) superficial veins of the leg and thigh.
The lamellated connective tissue constituting the thickest layer of the cornea between the Bowman and Descemet membranes. (MeSH)
Corneal Stroma
19: 414665-369928
Physical location of SLI_Gene
Scalp
The skin which covers the top of the head and which is usually covered by hair.
Flood Field
The radiation field created by a flood source for purposes of obtaining a flood image.
Physical location of IRS1_Gene
2: 227489980-227425443
Ovarian Capsule
Mature Thymocyte
A cell derived in the thymus from a T cell progenitor and then differentiates into a T-Lymphocyte.
Coronary Sinus
Chromosome 1 Physical Location
Physical location of CXCL14_Gene
5: 134942868-134934274
External Ear
The external part of the ear.
EAR, OUTER
Auricle
PINNA
Ear, External
8p21-p11.2
A chromosome band present on 8p
Physical location of GDF10_Gene
10: 48059172-48045795
8q24.1-q24.3
A chromosome band present on 8q
Dome of the Bladder
Superior Surface of Bladder
Superior Surface of the Bladder
BLADDER, DOME
Dome of Bladder
The upper, convex surface of the bladder.
A chromosome band present on 6p
6p22.3
Suppressor Cells
T-Lymphocytes, Suppressor-Effector
T-Lymphocyte, Suppressor-Effector
T Suppressor Cell
Subpopulation of CD8+ T-lymphocytes which suppress antibody production or inhibit cellular immune responses. Suppressor-effector cells execute the message received from suppressor-inducer cells.
Suppressor-Effector T-Lymphocyte
T-Cells, Suppressor-Effector
Suppressor T Lymphocyte
Cerebral Aqueduct
A channel that connects the third and fourth ventricles of the brain.
Aqueduct of Sylvius
Stratified Epithelium
1q41
A chromosome band present on 1q
Sphincter
Caudal Ridge
Oolemma
The specialized plasma membrane of an oocyte.
WD40 Repeats are found in signal transduction, mRNA processing, cytoskeletal assembly, and cell cycle proteins; none are catalytic. G-beta is the prototypic WD40 protein. WD-40 proteins contain 5-8 repeats of about 40 residues, with a central Trp-Asp (WD) motif. The repeats may span the entire protein or make up either terminal or the central section. WD40 domains serve as a platform to which proteins stably or reversibly bind; some may recognize phosphoSer and -Thr peptides. The repeat forms a closed ring propeller with seven blades each composed of a four-stranded anti-parallel b-sheet. Each repeat forms the first three strands of one blade and the last strand in the next blade. The last C-terminal repeat completes the blade of the first repeat. Residues on the propeller top surface likely coordinate interactions with other proteins or ligands.
WD Repeat
WD Domain
G-Beta Repeat
Tryptophan-Aspartate Repeat
Trp-Asp Repeat
WD40 Domain
The transparent extraembryonic sac that holds the developing fetus and surrounding amniotic fluid.
Amniotic Sac
21q22.1
A chromosome band present on 21q
FHA Domain
The FHA (Forkhead-Associated) domain is a phosphopeptide recognition domain found in many regulatory proteins. It displays specificity for phosphothreonine-containing epitopes but will also recognize phosphotyrosine with relatively high affinity. It spans approximately 80-100 amino acid residues folded into an 11-stranded sandwich, which sometimes contain small helical insertions between the loops connecting the strands. To date, genes encoding FHA-containing proteins have been identified in eubacterial and eukaryotic but not aracheal genomes. The domain is present in a diverse range of proteins, such as kinases, phosphatases, kinesins, transcription factors, RNA-binding proteins and metabolic enzymes which partake in many different cellular processes. DNA repair, signal transduction, vesicular transport and protein degradation are just a few examples.
Forkhead-Associated Domain
Waldeyer's Tonsillar Ring
Waldeyer's Ring
The ring of lymphoid tissue located in the pharynx, consisting of the pharyngeal, tubal, palatine, and lingual tonsils.
6p22.1
A chromosome band present on 6p
The part of the face between the eyebrows and the normal hairline.
Forehead
Tumor Infiltrating Lymphocyte
Lymphocytes that show specificity for autologous tumor cells and can infiltrate a tumor.
Tumor Infiltrating Lymphocytes
Lymphocytes, Tumor-Infiltrating
TIL
Lymphocyte, Tumor-Infiltrating
Pituitary Stalk
Oropharynx
The part of the pharynx between the soft palate and the upper portion of the epiglottis.
16: 55950219-55957602
Physical location of CCL22_Gene
A chromosome band present on 21q
21q22.2
A transparent homogeneous acellular layer, 6 to 9 um thick, lying between the basal lamina of the outer layer of stratified epithelium and the substantia propria of the cornea; it is considered to be a basement membrane.
Bowman's Membrane
Urinary System Part
Facial Nucleus
Facial Nerve Nucleus
Serum
Sera
The clear portion of the blood that remains after the removal of the blood cells and the clotting proteins.
BH3 Domain
The alpha-helical BH3 domain (9 amino acids) represents a minimal death domain and is essential for the activity of pro-apoptotic members of the bcl-2 family. Some of these proteins only contain a BH3 domain.
Interlobular Artery
21q22.3
A chromosome band present on 21q
Papillary Muscle
Thyroid Primordium
20: 44070954-44078606
Physical location of MMP9_Gene
A chromosome band present on 2p
2p22.3-p21
2q37.2
A chromosome band present on 2q
Cavum Conchae
A chromosome band present on 5q
5q11.2-q13.1
Chromosome 9 Physical Location
A chromosome band present on 12p.
12p13.31
Olfactory Epithelial Cells
Olfactory Epithelial Cell
A cell found in the pseudostratified epithelium lining the olfactory region of the nasal cavity. The olfactory epithelium has three major cell types - olfactory receptor cells, basal cell and sustentacular cells.
11: 77806414-77603990
Physical location of GAB2_Gene
11: 74678732-74654811
Physical location of ARRB1_Gene
Physical location of CYP3A4_Gene
7: 99026459-98999255
Physical location of GPR2_Gene
17: 38087371-38084961
Any of the fluid-filled vesicles in the mammalian ovary containing a maturing ovum.
Graafian Follicle
Mature Follicle
Vesicular Ovarian Follicle
Secondary Ovarian Follicle
Antral Follicle
Stoma
Lymph Node Efferent Vessel
Tail of the Spermatozoon
Joint of the Pelvic Girdle
10: 93673716-93779349
Physical location of BTAF1_Gene
KDEL Domain
A motif found at the C termini of several luminal proteins of the ER that serves to mediate the retention of resident proteins of the ER lumen through retrieval from post-ER compartments ER via a transport mechanism involving vesicular and tubular elements.
KDEL Motif
Lamella of Harvesian System
16: 87397687-87413167
Physical location of CDT1_Gene
Thymic Vein
Gastric Pit
Gastric Foveola
1q44
A chromosome band present on 1q
One of the two channels of the nose, from the point where they divide to the external opening.
External Nare
Nostril
Alveolar Cell
A cell found in the walls of the pulmonary alveoli; the term is limited to alveolar epithelial cells (type I and type II alveolar cells).
14q32.33
A chromosome band present on 14q
LINES
LINE
LINEs. Highly repeated sequences, 6000-8000 base pairs in length that contain RNA polymerase II promoters. They also have a region with sequence similarity to the reverse transcriptase of retroviruses, but they do not contain LTRs (long terminal repeats).
Long Interspersed Element
Glans Clitoris
A chromosome band present on 14q
14q32.1-q32.2
8: 82552004-82553481
Physical location of FABP4_Gene
Esophageal Lamina Propria
11q23.1-q23.2
A chromosome band present on 11q
Right Fallopian Tube
The fallopian tube that extends from the uterus to the ovary in the right side of the pelvic cavity.
A chromosome band present on 1q
1q43
Extracellular Structure
Any structures that are not enclosed intracellularly are considered extracellular structure, including structures on the cell surface. (NCI)
11pter-p13
A chromosome band present on 11p
VALVE, AORTIC
A valve that is located between and controls the flow of blood from the left ventricle of the heart and the aorta.
Aortic Valve
Renal Artery
Incisor
One of the teeth in front of the canines in either jaw designed for cutting or gnawing.
TOOTH, INCISOR
A chromosome band present on 12p
12p13.32
CA4 Field of the Cornu Ammonis
Olfactory Bulb
Anatomical structure located in the vertebral forebrain that receives neural input regarding odors that have been detected by cells within the nasal cavity. The axons of olfactory receptor cells extend into the olfactory bulb.
BRAIN, OLFACTORY BULB
The portion of the mitochondrial ATP synthase that is found inside the matrix. This protein complex can catalyze the conversion of adenosine diphosphate to adenosine triphosphate.
Elementary Particles
ATP Synthase F1 Particle
F1 Particle
A protein complex found in the membrane of the endosome that transports hydrogen ions into the lumen to increase its acidity.
Endosome Proton Pump
H+ Pump
Endosome Proton
A chromosome band present on 11q
11q23.1-q23.3
A chromosome band present on 1q
1q42
A thin hyaline membrane between the chief part of the sclera and the endothelial layer of the cornea.
Descemet's Membrane
A blood vessel that carries blood toward the heart.
Vein
Venous
A chromosome band present on 11q
11q21-q22
RHO Effector Domain
The REM repeat, which is also called rho effector or HR1 domain, was first described as a three times repeated homology region of the N-terminal non-catalytic part of protein kinase PRK1(PKN). The first two of these repeats were later shown to bind the small G protein rho known to activate PKN in its GTP-bound form. Similar rho-binding domains also occur in a number of other protein kinases and in the rho-binding proteins rhophilin and rhotekin. Recently, the structure of the N-terminal REM repeat complexed with RhoA has been determined by X-ray crystallography. It forms an antiparallel coiled-coil fold termed an ACC finger.
REM Repeat
Hr1 Repeat
HR1 Domain
Infundibular Cusp
Physical location of IRAK4_Gene
12: 42439047-42468166
Precentral Artery