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Ulf Schwarz
Initial Version
release date 28/02/2017
Institute for Formal Ontology and Medical Information Science (IFOMIS)
Viral Desease Ontology Trunk
participates in at some time
has participant at some time
concretizes
function of at all times
quality of at all times
role of at all times
has quality at some time
disposition of at all times
has continuant part at all times
has disposition at some time
occupies temporal region
has temporal occupant
span-of
has role at all times
has proper continuant part at some time
proper part of continuant at some time
part of continuant at some time
has continuant part at some time
has proper temporal part
history of
has continuant part at all times that part exists
has role
has quality at all times
The occurrence in an individual of two or more cell populations of different chromosomal constitutions, derived from different individuals. This contrasts with mosaicism in which the different cell populations are derived from a single individual.
NCIT
Chimärismus
chimerism
UMLS_CUI C0333678
White blood cell
Leukozyt
leukocyte
http://purl.org/sig/ont/fma/fma62854
Granular leucocyte
Granulocyte
granular leukocyte
granulärer Leukozyt
http://purl.org/sig/ont/fma/fma62855
Agranular leukocyte
Mononuclear leukocyte
agranulärer Leukozyt
nongranular leukocyte
Stammzelle
stem cell
Probe
A planned process that captures an image of an object.
OBI
http://purl.obolibrary.org/obo/OBI_0001007
Bilderzeugung
image creation
A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs.
http://en.wikipedia.org/wiki/Organism
http://purl.obolibrary.org/obo/OBI_0100026
Organismus
organism
Krankenhaus
Alter
cardinality
extra or missing physical or functional parts
has or lacks parts of type
mereological quality
number
number of
Anzahl
somatic stem cell
somatische Stammzelle
Bone marrow-derived hemopoietic stem cell
blutbildende Stammzelle aus Knochenmark
multipotente Stammzelle
multipotent stem cell
Knochenmarkstammzelle
bone marrow stem cell
blood-forming stem cell
blutbildende Stammzelle
hemopoietic stem cell
Blutstammzelle
Peripheral blood stem cell
Institutionsidentifikationsnummer
Zelle
1
Bestrahlung
A patient is any recipient of health care services. The patient is most often ill or injured and in need of treatment by a physician, advanced practice registered nurse, physiotherapist, physician assistant, psychologist, dentist, podiatrist, veterinarian, or other health care provider.
https://en.wikipedia.org/wiki/patient
Als Patient bzw. Patientin (aus lateinisch patiens, deutsch ‚geduldig‘, ‚aushaltend‘, ‚ertragend‘, adjektivisches 1. Partizip von pati, deutsch ‚erdulden‘, ‚leiden‘ wird ein Mensch bezeichnet, der ärztliche Dienstleistungen oder Dienstleistungen anderer Personen, die eine Heilbehandlung durchführen, in Anspruch nimmt. Dabei kann es sich um die Vorbeugung, Feststellung oder medizinische Behandlung von Krankheiten oder Folgen eines Unfalls handeln.
Inflammation of the bladder resulting in bloody urine
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C114666
UMLS_CUI C0085692
hämorrhagische Zystitis (HC)
hemorrhagic cystitis
An infection caused by the BK virus. It usually causes an asymptomatic infection, except in immunocompromised individuals where it may cause nephropathy or hemorrhagic cystitis.
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C123276
UMLS_CUI C1096691
bk virus infection
A clinical treatment in which hematopoietic stem cells are transferred from a HLA half-matched donor to a recipient.
NCIT
http://purl.obolibrary.org/obo/NCIT_C138187
HLA-Haploidentical Hematopoietic Cell Transplantation
haploidentical hematopoietic cell transplantation
A genus of the family herpesviridae, subfamily betaherpesvirinae, infecting the salivary glands, liver, spleen, lungs, eyes, and other organs, in which they produce characteristically enlarged cells with intranuclear inclusions.
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C14196
CMV
CYTOMEGALOVIRUS
Cytomegalovirus (CMV)
HHV-5
HUMAN HERPESVIRUS 5
cytomegalovirus
FDA_UNII_Code 7COI029E6K
NCBI_Taxon_ID 10358
UMLS_CUI C0010825
A virus that has DNA as its genetic material and does not use an RNA intermediate during replication.
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C14200
DNA Virus
dna virus
UMLS_CUI C0012923
A species of Herpetoviridae that is responsible for infectious mononucleosis (glandular fever). Discovered in 1964, this virus has been associated with Burkitt's lymphoma in South African children and with nasopharyngeal carcinoma in Asian populations.
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C14204
EBV
Epstein Barr Virus
FDA_UNII_Code 2A26YW7PNX
HHV-4
HUMAN HERPESVIRUS 4
Lymphocryptovirus
Virus-Epstein-Barr
epstein-barr virus
NCBI_Taxon_ID 10376
UMLS_CUI C0014644
A heterogeneous family of morphologically similar viruses, all of which contain double-stranded DNA and which infect man and a wide variety of other vertebrates. Infections produce type A inclusion bodies; in many instances, infection may remain latent for many years, even in the presence of specific circulating antibodies. Virions are enveloped, ether-sensitive, and vary up to 200 nm in diameter; the nucleocapsids are 100 nm in diameter and of icosahedral symmetry, with 162 capsomeres. The family includes herpes simplex virus, cytomegalovirus, EB virus (all of which infect humans) and many others.
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C14217
Herpes Virus
Herpesviridae
UMLS_CUI C0019369
Virus-Herpes
Herpesvirus
herpesvirus
NCBI_Taxon_ID 10292
A non-taxonomic group of animal viruses associated with or causing papillomas or polyomas.
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C14253
UMLS_CUI C0319132
papovavirus
A genus of double-stranded DNA viruses. The viral particles are not enveloped and are icosahedral in structure.
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C14260
polyomavirus
NCBI_Taxon_ID 10624
UMLS_CUI C0032556
A virus that has double stranded DNA as its genetic material.
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C14348
UMLS_CUI C1512048
dsDNA Virus
Doppelsträngiger DNA Virus
double stranded dna virus
A therapeutic procedure that involves the transplantation of hematopoietic stem cells, either with the patient as their own donor or from a donor to a patient. This can be used for treatment of malignant and non-malignant diseases.
NCIT
http://purl.obolibrary.org/obo/NCIT_C15431
HCT
stem cell transplantation
hematopoietic cell transplantation
Stem cell transfer or transplantation in which the patient is his own donor.
NCIT
http://purl.obolibrary.org/obo/NCIT_C16039
autologous stem cell transplantation
autologous hematopoietic stem cell transplantation
A small volume of blood removed for testing or storage.
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17610
Blutprobe
blood sample
The selection and obtaining of small representative quantities of biological material for the purpose of analysis; also, in biomedical statistics, sampling is the selection and implementation of statistical observations in order to estimate properties of an underlying population; also, in environmental science, the collection of representative specimens analyzed to characterize site conditions.
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25662
Probennahme
sampling
A disorder resulting from the presence and activity of a microbial, viral, fungal, or parasitic agent. It can be transmitted by direct or indirect contact.
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26726
Infectious Disease
UMLS_CUI C0009450
infectious disorder
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27233
UMLS_CUI C1336809
transplant-related disorder
A group of non-neoplastic and neoplastic disorders resulting from the deregulation and/or deficiency of immune system functions. It includes autoimmune disorders (e.g., lupus erythematosus, dermatomyositis, rheumatoid arthritis), congenital and acquired immunodeficiency syndromes including the acquired immune deficiency syndrome (AIDS), and neoplasms (e.g., lymphomas and malignancies secondary to transplantation).
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27351
Immunodeficiency and Immunosuppression Disorders
UMLS_CUI C1334156
immune system and related disorders
The determination of the number of red blood cells, white blood cells, and platelets in a blood sample.
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28133
CBC
FBC
Full Blood Count
Complete Blood Count
UMLS_CUI C0005771
blood cell count
A reaction, which may be fatal, in an immunocompromised subject (host) who has received an antigenically incompatible tissue transplant (graft) from an immunocompetent donor. The reaction is secondary to the activation of the transplanted cells against those host tissues that express an antigen not expressed by the donor, and is seen most commonly following bone marrow transplantation; acute disease is seen after 5-40 days, and chronic disease occurs weeks to months after transplantation.
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C306
GVHD
Graft vs Host Disease
Graft-Versus-Host-Disease
Runt Disease
UMLS_CUI C0018133
graft-versus-host disease
graft versus host disease
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3439
UMLS_CUI C0042769
viral infection
A non-neoplastic or neoplastic disorder that develops in a patient with immunodeficiency. Representative examples include AIDS-related disorders and disorders that develop following organ transplantation.
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C35686
Immunodepression-Related Disorder
Immunosuppression disorders
Immunosuppression-Related Disorder
UMLS_CUI C1334159
immunodeficiency-related disorder
A facility equipped and competent to conduct scientific experiments, observations, tests, investigations, and/or to manufacture chemicals or medical products.
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C37984
Labor
laboratory
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C38759
EBV Infection
UMLS_CUI C0149678
epstein-barr virus infection
A clinical treatment in which hematopoietic stem cells (HSCs) are transferred from one genetically dissimilar individual to another.
NCIT
http://purl.obolibrary.org/obo/NCIT_C46089
allogeneic hematopoietic stem cell transplantation
Post-transplant lymphoproliferative disorder (PTLD) is a polyclonal (benign) or clonal (malignant) proliferation of lymphoid cells that develops as a consequence of immunosuppression in a recipient of a solid organ or bone marrow allograft. PTLDs comprise a spectrum ranging from early, Epstein-Barr virus (EBV)-driven polyclonal lymphoid proliferations to EBV-positive or EBV- negative lymphomas of predominantly B-cell or less often T-cell type. (WHO, 2001)
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4727
ICD-O-3_Code 9971/1
PTLD
UMLS_CUI C0432487
post-transplant lymphoproliferative disorder
A laboratory test to measure hematopoietic components and investigate hematologic disorders in a blood sample.
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C49286
Blood Test
Hematology Procedure
UMLS_CUI C0200627
hematology test
A syndrome of immunologically mediated tissue damage that may occur following an allogeneic transplant, usually affecting the skin, liver, and GI tract. The onset is usually within one hundred days of transplantation or immunologic manipulation.
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4980
UMLS_CUI C0856825
aGvHD
acute graft versus host disease
A syndrome of immunologically mediated tissue damage that may occur following an allogeneic transplant, and may affect multiple organs with manifestations similar to autoimmune diseases. The onset is usually within three years of transplantation or immunologic manipulation.
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4981
Chronic GVHD
Graft versus host disease, chronic
UMLS_CUI C0867389
chronische GvHD
chronic graft versus host disease
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C53529
Non-Neoplastic Disease
Non-neoplastic condition, NOS
Non-neoplastic disorder, NOS
UMLS_CUI C1709246
non-neoplastic disorder
A herpesvirus infection caused by Cytomegalovirus. Healthy individuals generally do not produce symptoms. However, the infection may be life-threatening in affected immunocompromised patients. The virus may cause retinitis, esophagitis, gastritis, and colitis. Morphologically, it is characterized by the presence of intranuclear inclusion bodies.
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C53649
CMV Infection
HCMV Infection
UMLS_CUI C0010823
cytomegaloviral infection
A classification of blood based on the presence or absence of inherited antigenic substances on the surface of erythrocytes.
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C76244
Blutgruppe
blood group
A blood group system based on recognition of inherited differences in the H antigen as expressed on erythrocytes.
NCIT
http://purl.obolibrary.org/obo/NCIT_C76245
AB0 blood group
A blood group indicating the presence on erythrocytes of only the A form of the H Antigen.
NCIT
http://purl.obolibrary.org/obo/NCIT_C76246
Blutgruppe A
blood group A
A blood group indicating the presence on erythrocytes of only the B form of the H Antigen.
NCIT
http://purl.obolibrary.org/obo/NCIT_C76247
Blutgruppe B
blood group B
A blood group indicating the presence on erythrocytes of both the A and B forms of the H Antigen
NCIT
http://purl.obolibrary.org/obo/NCIT_C76248
Blutgruppe AB
blood group AB
A blood group indicating the absence on erythrocytes of both the A and B forms of the H Antigen.
NCIT
http://purl.obolibrary.org/obo/NCIT_C76249
Blutgruppe 0
blood group 0
A fictitious name used when the person performs a particular social role.
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80244
UMLS_CUI C0033824
Pseudonym
pseudonym
The circumstance or condition that results in the death of a living being.
NCIT
http://purl.obolibrary.org/obo/NCIT_C81239
COD
Todesursache
cause of death
A double stranded DNA virus in the polyomavirus family. It is widespread but usually causes an asymptomatic infection, except in immunocompromised individuals.
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C89820
BK POLYOMAVIRUS
BKV
NCBI_Taxon_ID 10629
UMLS_CUI C0005670
Papovavirus BKV
Polyomavirus BK
Polyomavirus Type BK
bk virus
An infectious or non infectious disorder characterized by signs and symptoms derived from focal or extensive tissue infiltration by acute (e.g., polymorphonuclear) or chronic (e.g., lymphocytic-plasmacytic) inflammatory cells. Representative examples of infectious disorders include viral infections, bacterial infections, and parasitic infections. Representative examples of non-infectious inflammatory disorders include inflammatory bowel disease and inflammatory polyps.
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C93210
UMLS_CUI C1290884
inflammatory disorder
http://purl.obolibrary.org/obo/ncbitaxon.owl
UMLS_CUI C0042776
Virus
virus
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C14283
a portion of urine collected from an organism
OBI
http://purl.obolibrary.org/obo/OBI_0000651
Urinprobe
urine specimen
http://purl.org/sig/ont/fma/fma62863
Lymphozyt
lymphocyte
http://purl.org/sig/ont/fma/fma62864
Monozyt
monocyte
Cell which has as its direct part a maximally connected part of protoplasm. Examples: hepatocyte, erythroblast, skeletal muscle cell, megakaryocyte.
FMA
http://purl.org/sig/ont/fma/fma67513
Kernhaltige Zelle
nucleated cell
ttp://purl.org/sig/ont/fma/fma70336
Blutzelle
Haemal cell
hematocyte
hemocyte
Hämozyten
hemal cell
http://purl.org/sig/ont/fma/fma70340
differentiated hemal cell
Nucleated cell which has one or more diploid sets (46 pairs) of chromosomes.
FMA
http://purl.org/sig/ont/fma/fma72300
Diploid cell
somatic cell
somatische Zelle
Laboreingang
laboratory receipt
A directive information entity that represents a mathematical relationship which relates changes in a given response to changes in one or more factors. A statistical model is a formalization of relationships between variables in the form of mathematical equations.
statistical model
http://www.itl.nist.gov/div898/handbook/pri/section7/pri7.htm; http://en.wikipedia.org/wiki/Statistical_model
http://purl.obolibrary.org/obo/OBCS_0000035
Modell
model
OBCS: Ontology of Biological and Clinical Statistics
http://identifiers.org/mamo/MAMO_0000037
Prädiktives Modell
predictive model
Institutionsname
institution name
Spender-Rolle
donor role
Organ donor is a person who allows an organ of theirs to be removed, legally, either by consent while the donor is alive or after death with the assent of the next of kin.
IFOMIS
Spender
donor
IDDonor
Spender ID
donor identifier
Verwandtschaftsgrad
degree of kinship
graft loss
GvHD Hautstadium
stage of skin GvHD
GvHD Leberstadium
stage of liver GvHD
GvHD Darmstadium
stage of instestine GvHD
graft loss nach TX in Tagen
time of graft loss in days after stem cell transplantation
A quality that inheres in an bearer by virtue of how that bearer interacts with radiation.
PATO
http://purl.obolibrary.org/obo/PATO_0001739
radiation quality
A radiation quality inhering in a bearer by virtue of what the bearer receives as a result of being exposed to ionizing radiation.
PATO
http://purl.obolibrary.org/obo/PATO_0001744
radiation exposure
saGvHD
late acute graft versus host disease
stage of chronic graft versus host disease
aGvHD Grad
stage of acute graft versus host disease
date 4 nach TX
GvHD Auftreten nach TX in Tagen
The volume of packed RED BLOOD CELLS in a blood specimen. The volume is measured by centrifugation in a tube with graduated markings, or with automated blood cell counters. It is an indicator of erythrocyte status in disease. For example, ANEMIA shows a low value; POLYCYTHEMIA, a high value.
EFO
Hämatokrit
hematocrit
A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years.
Leukemia with an acute onset, characterized by the presence of lymphoblasts in the bone marrow and the peripheral blood. It includes the acute B lymphoblastic leukemia and acute T lymphoblastic leukemia.
NCIT
leukemia
umls_cui: C0023418
A clonal (malignant) hematopoietic disorder with an acute onset, affecting the bone marrow and the peripheral blood. The malignant cells show minimal differentiation and are called blasts, either myeloid blasts (myeloblasts) or lymphoid blasts (lymphoblasts).
NCIT
acute leukemia
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3167
ALL
Precursor Lymphoblastic Leukemia
acute lymphoblastic leukemia
A clonal expansion of myeloid blasts in the bone marrow, blood or other tissues. The classification of acute myeloid leukemias (AMLs) encompasses four major categories: 1) AML with recurrent genetic abnormalities; 2) AML with multilineage dysplasia; 3) Therapy-related AML; 4) AML not otherwise specified. The required bone marrow or peripheral blood blast percentage for the diagnosis of AML is 20% (WHO classification).
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3171
AML
Acute Granulocytic Leukemia
acute myeloblastic leukemia
The most common type of chronic lymphoid leukemia. It comprises 90% of chronic lymphoid leukemias in the United States. Morphologically, the neoplastic cells are small, round B-lymphocytes. This type of leukemia is not considered to be curable with available therapy. (WHO, 2001)
NCIT
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3163
CLL
Chronic B-Cell Lymphocytic Leukemia
chronic lymphocytic leukemia
Der Begriff myelodysplastische Syndrome (MDS) umfasst eine Reihe von Erkrankungen des Knochenmarks, bei denen zu wenig funktionstüchtige Blutzellen gebildet werden. Die einzelnen MDS-Formen unterscheiden sich hinsichtlich ihres Verlaufs, der Behandlungsmöglichkeiten und des Risikos, in eine akute Leukämie überzugehen. Die Erkrankung gehört zu den häufigsten bösartigen Bluterkrankungen des Erwachsenen und tritt vor allem bei Patienten über 60 Jahren auf. Auch wenn MDS heute noch nicht medikamentös heilbar sind, konnten in den letzten Jahren die Diagnostik und die Behandlungsmöglichkeiten durch neue wissenschaftliche Erkenntnisse stetig weiter verbessert werden.
https://www.kompetenznetz-leukaemie.de/content/patienten/leukaemien/mds/
MDS
Myelodysplastische Syndrome
Auftragstag
Laborauftrag
GVHD-Grad undefined
GVHD-Grad undefiniert
Todeszeitpunkt in Tagen ab Stammzelltranplantation
time of death in days after stem cell transplantation
Alter bei Stammzellentransplantation
age at stem cell transplantation
GVHD-Grad IV
GVHD-Grade 4
GVHD-Grad III
GVHD-Grade 3
GVHD-Grad II
GVHD-Grade 2
GVHD-Grad I
GVHD-Grade 1
GVHD-Grad
http://purl.obolibrary.org/obo/CHEBI_33582
carbon group molecular entity
A main group molecular entity that contains one or more atoms of a p-block element.
CHEBI
http://purl.obolibrary.org/obo/CHEBI_33675
p-block compounds
p-block molecular entities
p-block molecular entitiy
p-block molecular entity
realized by
realizes
is concretized as
has function at some time
has role
has proper continuant part at all times
has material basis at all times
has occurrent part
has proper occurrent part
proper temporal part of
proper part of occurrent
Kohlenstoffhydrat
Lipide
Rezidiv
m
männlich
weiblich
f
w
Alter bei Diagnose
Todeszeitpunkt