format-version: 1.2 date: 11:05:2009 15:09 saved-by: Erik Segerdell auto-generated-by: OBO-Edit 1.101 subsetdef: anatomical_site_slim "Anatomical Site slim" subsetdef: frequent_anatomy_items "Frequently Used Anatomy slim" subsetdef: organism_views "Organism View slim" subsetdef: sectional_anatomy_items "Sectional Anatomy Item slim" synonymtypedef: PLURAL "Plural" default-namespace: xenopus_anatomy namespace-id-rule: * XAO:$sequence(7,3000,9999999)$ [Term] id: XAO:0000000 name: Xenopus anatomical entity [Term] id: XAO:0000001 name: ectoderm def: "Primary germ layer that is the outer of the embryo's germ layers and gives rise to epidermis and neural tissue." [OMD:ectoderm "CancerWeb Online Medical Dictionary"] subset: frequent_anatomy_items xref: ZFA:0000016 is_a: XAO:0003011 ! primary germ layer [Term] id: XAO:0000002 name: fin def: "Surface structure that has an important role in tadpole locomotion. It starts to develop along the trunk and tail of the embryo at the tail bud stage and continues to grow until the start of metamorphosis when it begins to regress. It consists of flattened epidermal cells elevated into a keel-like structure by a supporting core of mesenchyme and extracellular matrix." [PMID:15188431 "Tucker AS and Slack JM (2004)"] subset: frequent_anatomy_items xref: ZFA:0000108 is_a: XAO:0003028 ! surface structure relationship: end_stage XAO:1000078 ! NF stage 66 relationship: part_of XAO:0000001 ! ectoderm relationship: start_stage XAO:1000041 ! NF stage 25 [Term] id: XAO:0000003 name: outer fin is_a: XAO:0000002 ! fin [Term] id: XAO:0000004 name: inner fin is_a: XAO:0000002 ! fin [Term] id: XAO:0000005 name: olfactory placode def: "A thick plate of cells derived from the neural ectoderm in the head region of the embryo that develops into the olfactory region of the nasal cavity." [NLM:olfactory+placode "MedlinePlus Medical Dictionary"] synonym: "nasal placode" RELATED [] xref: ZFA:0000048 is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000041 ! epidermis inner layer relationship: develops_from XAO:0000320 ! sensorial layer relationship: part_of XAO:0003196 ! olfactory system relationship: start_stage XAO:1000039 ! NF stage 23 [Term] id: XAO:0000006 name: otic vesicle alt_id: XAO:0000184 subset: frequent_anatomy_items synonym: "ear vesicle" RELATED [] xref: ZFA:0000051 is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000223 ! otic placode relationship: end_stage XAO:1000061 ! NF stage 49 relationship: part_of XAO:0003195 ! vestibuloauditory system relationship: start_stage XAO:1000043 ! NF stage 27 [Term] id: XAO:0000007 name: lower eyelid is_a: XAO:0003028 ! surface structure relationship: part_of XAO:0000179 ! eye [Term] id: XAO:0000008 name: lens def: "Transparent, biconvex structure in the eye that, along with the cornea, helps to refract light to be focused on the retina." [WIKI:Lens_(anatomy) "Wikipedia (en)"] xref: ZFA:0000035 relationship: develops_from XAO:0000240 ! lens placode relationship: part_of XAO:0000179 ! eye relationship: start_stage XAO:1000048 ! NF stage 33 and 34 [Term] id: XAO:0000009 name: retina def: "Sensory membrane that lines the posterior chamber of the eye and functions as the immediate instrument of vision by receiving the image formed by the lens and converting it into chemical and nervous signals which reach the brain by way of the optic nerve." [NLM:retina "MedlinePlus Medical Dictionary"] xref: ZFA:0000152 relationship: part_of XAO:0000179 ! eye relationship: start_stage XAO:1000037 ! NF stage 21 [Term] id: XAO:0000010 name: brain def: "Organ that is a component of the central nervous system and is responsible for the coordination and control of bodily activities and the interpretation of information from the senses. It appears when the neural tube segregates in forebrain, midbrain, and hindbrain at NF stage 22. The general pattern of the brain has been mainly established at NF stage 28. Yolky material is consumed and the fibre tracts and later the commissures develop. In general all of its parts are well developed at NF stage 53 and later development consists mainly of growth and some further cytological differentiation. In the period of metamorphosis only topographical changes take place." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 30-59)", OMD:brain "CancerWeb Online Medical Dictionary"] subset: frequent_anatomy_items xref: ZFA:0000008 relationship: part_of XAO:0000215 ! central nervous system relationship: start_stage XAO:1000038 ! NF stage 22 [Term] id: XAO:0000011 name: forebrain def: "The part of the brain that is the anterior of its three primary divisions and that includes the telencephalon and diencephalon." [NLM:forebrain "MedlinePlus Medical Dictionary"] synonym: "prosencephalon" RELATED [] xref: ZFA:0000109 relationship: develops_from XAO:0000307 ! anterior neural tube relationship: part_of XAO:0000010 ! brain relationship: start_stage XAO:1000038 ! NF stage 22 [Term] id: XAO:0000012 name: telencephalon xref: ZFA:0000079 relationship: part_of XAO:0000011 ! forebrain [Term] id: XAO:0000013 name: diencephalon xref: ZFA:0000101 relationship: part_of XAO:0000011 ! forebrain [Term] id: XAO:0000014 name: midbrain def: "The part of the brain that is the middle of its three primary divisions." [NLM:midbrain "MedlinePlus Medical Dictionary"] synonym: "mesencephalon" RELATED [] xref: ZFA:0000128 relationship: develops_from XAO:0000307 ! anterior neural tube relationship: part_of XAO:0000010 ! brain relationship: start_stage XAO:1000038 ! NF stage 22 [Term] id: XAO:0000015 name: hindbrain def: "The part of the brain that is the posterior of its three primary divisions." [NLM:hindbrain "MedlinePlus Medical Dictionary"] synonym: "rhombencephalon" RELATED [] xref: ZFA:0000029 relationship: develops_from XAO:0000250 ! posterior neural tube relationship: part_of XAO:0000010 ! brain relationship: start_stage XAO:1000038 ! NF stage 22 [Term] id: XAO:0000016 name: midbrain-hindbrain boundary def: "The part of the brain that is the morphological boundary between the midbrain and hindbrain and that is the location of an organizing center which patterns the midbrain and hindbrain primordia of the neural plate." [GO:0021555] synonym: "isthmus" RELATED [] synonym: "MHB" EXACT [] xref: ZFA:0000042 relationship: part_of XAO:0000010 ! brain relationship: part_of XAO:0000249 ! neural plate relationship: start_stage XAO:1000038 ! NF stage 22 [Term] id: XAO:0000017 name: hypophysis alt_id: XAO:0000161 synonym: "pituitary gland" RELATED [] xref: ZFA:0000118 relationship: part_of XAO:0000011 ! forebrain relationship: part_of XAO:0000158 ! endocrine system relationship: start_stage XAO:1000052 ! NF stage 40 [Term] id: XAO:0000018 name: genital ridge def: "The precursor to the gonads." [WIKI:Gonadal_ridge "Wikipedia (en)"] relationship: develops_from XAO:0000085 ! intermediate mesoderm relationship: part_of XAO:0000140 ! urogenital system [Term] id: XAO:0000020 name: spinal cord def: "Elongated, approximately cylindrical part of the central nervous system that lies in the vertebral canal and from which the spinal nerves emerge." [OMD:spinal+cord "CancerWeb Online Medical Dictionary"] xref: ZFA:0000075 relationship: develops_from XAO:0000250 ! posterior neural tube relationship: part_of XAO:0000215 ! central nervous system relationship: start_stage XAO:1000038 ! NF stage 22 [Term] id: XAO:0000021 name: ventricular zone subset: anatomical_site_slim xref: ZFA:0001083 is_a: XAO:0003186 ! anatomical region [Term] id: XAO:0000022 name: roof plate def: "Organizing center located at the dorsal midline of the neural tube that influences the development of the nervous system, controlling the specification and differentiation of dorsal neuronal cell types." [PMID:15378040 "Chizhikov VV and Millen KJ"] synonym: "roofplate" EXACT [] synonym: "spinal cord roof" RELATED [] xref: ZFA:0007058 relationship: part_of XAO:0000020 ! spinal cord [Term] id: XAO:0000023 name: skin def: "Surface structure that consists of the external membranous integument of the animal." [OMD:skin "CancerWeb Online Medical Dictionary"] synonym: "integument" RELATED [] is_a: XAO:0003028 ! surface structure relationship: part_of XAO:0000176 ! dermal system [Term] id: XAO:0000024 name: mandibular crest relationship: part_of XAO:0001001 ! cranial neural crest [Term] id: XAO:0000025 name: hyoid crest relationship: part_of XAO:0001001 ! cranial neural crest [Term] id: XAO:0000026 name: branchial crest relationship: part_of XAO:0001001 ! cranial neural crest [Term] id: XAO:0000027 name: cranial ganglion def: "Ganglion that is located in the head." [ZFA:0000013] synonym: "cranial ganglia" RELATED PLURAL [] xref: ZFA:0000013 is_a: XAO:0000209 ! ganglion relationship: develops_from XAO:0000270 ! sensorial layer of neurectoderm relationship: start_stage XAO:1000044 ! NF stage 28 [Term] id: XAO:0000028 name: epidermis def: "The outer epithelial layer of the external integument of the body that is derived from the embryonic epiblast." [BTO:0000404] subset: frequent_anatomy_items synonym: "skin" BROAD [] xref: BTO:0000404 relationship: part_of XAO:0000001 ! ectoderm relationship: part_of XAO:0000023 ! skin relationship: start_stage XAO:1000023 ! NF stage 13 [Term] id: XAO:0000029 name: epidermis outer layer synonym: "epidermis epithelial layer" RELATED [] synonym: "periderm" RELATED [] xref: ZFA:0001185 is_a: XAO:0003045 ! epithelium relationship: part_of XAO:0000028 ! epidermis [Term] id: XAO:0000030 name: vitelline membrane relationship: part_of XAO:0000035 ! zygote [Term] id: XAO:0000031 name: ciliated cell def: "Cell type that has motile cilia and populates the skin of the embryo, arranged in the surface layer of the non-neural ectoderm in an ordered distribution." [PMID:10518489 "Deblandre GA et al."] xref: CL:0000064 is_a: XAO:0003012 ! cell relationship: part_of XAO:0000028 ! epidermis relationship: start_stage XAO:1000038 ! NF stage 22 [Term] id: XAO:0000032 name: stomodeal-hypophyseal primordium is_a: XAO:0003043 ! primordium relationship: develops_from XAO:0000320 ! sensorial layer relationship: start_stage XAO:1000036 ! NF stage 20 [Term] id: XAO:0000033 name: cement gland def: "A simple mucus-secreting structure that is positioned at the front of the embryo, attaches the newly hatched embryo to a support before the hatchling can swim well or feed, and marks the anterior-most dorsal ectoderm." [PMID:8787748 "Bradley L et al."] subset: frequent_anatomy_items is_a: XAO:0003028 ! surface structure relationship: develops_from XAO:0000049 ! cement gland primordium relationship: end_stage XAO:1000062 ! NF stage 50 relationship: start_stage XAO:1000044 ! NF stage 28 [Term] id: XAO:0000034 name: hatching gland synonym: "frontal gland" RELATED [] xref: ZFA:0000026 is_a: XAO:0003042 ! embryonic structure relationship: end_stage XAO:1000049 ! NF stage 35 and 36 relationship: part_of XAO:0000001 ! ectoderm relationship: start_stage XAO:1000025 ! NF stage 15 [Term] id: XAO:0000035 name: zygote def: "Cell resulting from the fusion of male and female gametes at fertilization." [OMD:zygote "CancerWeb Online Medical Dictionary"] synonym: "fertilized egg" EXACT [] xref: CL:0000365 is_a: XAO:0003012 ! cell relationship: start_stage XAO:1000001 ! NF stage 1 [Term] id: XAO:0000036 name: animal cap def: "Ectodermal roof of the blastocoel." [XB:curator "Xenbase"] synonym: "animal ectoderm" RELATED [] relationship: end_stage XAO:1000022 ! NF stage 12 relationship: part_of XAO:0000001 ! ectoderm relationship: start_stage XAO:1000016 ! NF stage 6 (32-cell) [Term] id: XAO:0000037 name: animal cap inner layer def: "Sensorial layer of blastocoel roof ectoderm." [XB:curator "Xenbase"] relationship: part_of XAO:0000036 ! animal cap [Term] id: XAO:0000038 name: animal cap outer layer def: "Superficial layer of blastocoel roof ectoderm." [XB:curator "Xenbase"] relationship: part_of XAO:0000036 ! animal cap [Term] id: XAO:0000039 name: anatomical site is_obsolete: true consider: XAO:0003186 [Term] id: XAO:0000040 name: head region subset: anatomical_site_slim is_a: XAO:0003186 ! anatomical region [Term] id: XAO:0000041 name: epidermis inner layer synonym: "epidermis sensorial layer" RELATED [] synonym: "stratum germinativum" RELATED [] relationship: part_of XAO:0000028 ! epidermis [Term] id: XAO:0000042 name: neuroectoderm def: "Embryonic ectoderm that gives rise to nervous tissue." [NLM:neuroectoderm "MedlinePlus Medical Dictionary"] synonym: "neural ectoderm" RELATED [] synonym: "neurectoderm" EXACT [] synonym: "presumptive central nervous system" RELATED [] xref: ZFA:0001120 is_a: XAO:0003042 ! embryonic structure relationship: part_of XAO:0000001 ! ectoderm relationship: start_stage XAO:1000032 ! NF stage 11.5 [Term] id: XAO:0000043 name: neuroectoderm outer layer relationship: part_of XAO:0000042 ! neuroectoderm [Term] id: XAO:0000044 name: neuroectoderm inner layer relationship: part_of XAO:0000042 ! neuroectoderm [Term] id: XAO:0000045 name: pre-chordal neural plate def: "The portion of neural plate anterior to the mid-hindbrain junction." [XB:curator "Xenbase"] synonym: "anterior neural plate" RELATED [] relationship: part_of XAO:0000249 ! neural plate [Term] id: XAO:0000046 name: chordal neural plate def: "The portion of neural plate posterior to the mid-hindbrain junction." [XB:curator "Xenbase"] synonym: "posterior neural plate" RELATED [] relationship: part_of XAO:0000249 ! neural plate [Term] id: XAO:0000047 name: notoplate relationship: part_of XAO:0000249 ! neural plate [Term] id: XAO:0000048 name: neural crest def: "A group of embryonic cells that loosen and separate from the neural plate and surrounding epidermis during neurulation and migrate to give several different lineages of adult cells." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 27)", OMD:neural+crest "CancerWeb Online Medical Dictionary"] subset: frequent_anatomy_items synonym: "neural crest material" RELATED [] xref: ZFA:0000045 relationship: part_of XAO:0000042 ! neuroectoderm relationship: start_stage XAO:1000025 ! NF stage 15 [Term] id: XAO:0000049 name: cement gland primordium is_a: XAO:0003043 ! primordium relationship: develops_from XAO:0000320 ! sensorial layer relationship: end_stage XAO:1000044 ! NF stage 28 relationship: start_stage XAO:1000025 ! NF stage 15 [Term] id: XAO:0000050 name: mesoderm def: "Primary germ layer that is the middle of the embryo's germ layers." [OMD:mesoderm "CancerWeb Online Medical Dictionary"] subset: frequent_anatomy_items synonym: "mesodermal mantle" RELATED [] xref: ZFA:0000041 is_a: XAO:0003011 ! primary germ layer [Term] id: XAO:0000051 name: dorsal aorta xref: ZFA:0000014 is_a: XAO:0003010 ! aorta relationship: develops_from XAO:0000085 ! intermediate mesoderm relationship: develops_from XAO:0000357 ! arterial endothelium [Term] id: XAO:0000052 name: cardinal vein is_a: XAO:0000115 ! vein relationship: develops_from XAO:0000085 ! intermediate mesoderm relationship: develops_from XAO:0000358 ! venous endothelium [Term] id: XAO:0000053 name: head mesoderm is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000079 ! prechordal plate relationship: start_stage XAO:1000037 ! NF stage 21 [Term] id: XAO:0000054 name: trunk region subset: anatomical_site_slim is_a: XAO:0003186 ! anatomical region [Term] id: XAO:0000055 name: notochord def: "A longitudinal flexible rod of cells that in the embryo forms the supporting axis of the body. It degenerates, beginning anteriorly, at NF stage 46. Its posterior portion is greatly reduced by NF stage 55 and the entire structure is gone by NF stage 65." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 102)", NLM:notochord "MedlinePlus Medical Dictionary"] subset: frequent_anatomy_items xref: ZFA:0000135 is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000205 ! axial mesoderm relationship: end_stage XAO:1000078 ! NF stage 66 relationship: start_stage XAO:1000033 ! NF stage 12.5 [Term] id: XAO:0000056 name: hypochord def: "Transient structure that lies immediately ventral to the notochord in the embryo, likely required for the formation of the dorsal aorta. A slight depression marks the future hypochord at NF stage 20 and its segregation from the dorsal endoderm begins at NF stage 24. It progresses from anterior to posterior and is complete by NF stage 28. At NF stage 32 it is present as a dorso-laterally flattened ribbon of yolk-laden cells. It degenerates by apoptosis and by NF stage 43 is no longer detectable as a distinct structure." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 37)", PMID:10648245 "Cleaver O et al."] synonym: "subnotochordal rod" RELATED [PMID:10648245 "Cleaver O et al."] xref: ZFA:0000031 relationship: end_stage XAO:1000055 ! NF stage 43 relationship: part_of XAO:0000090 ! endoderm relationship: start_stage XAO:1000040 ! NF stage 24 [Term] id: XAO:0000057 name: presomitic mesoderm synonym: "somitogenic mesoderm" RELATED [] is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000259 ! paraxial mesoderm [Term] id: XAO:0000058 name: somite def: "Any of the approximately 45 bilaterally paired blocks of mesoderm cells, lying on either side of the notochord and neural tube, and forming sequentially starting at the head during development of the embryo. Together they give rise to the axial skeleton (from the sclerotome), associated musculature (from the myotome), and dermis (from the dermatome)." [OMD:somite "CancerWeb Online Medical Dictionary", XB:curator "Xenbase"] subset: frequent_anatomy_items synonym: "somites" RELATED PLURAL [] synonym: "somitic mesoderm" RELATED [] xref: ZFA:0000155 is_a: XAO:0003042 ! embryonic structure relationship: end_stage XAO:1000059 ! NF stage 47 relationship: part_of XAO:0000050 ! mesoderm relationship: start_stage XAO:1000027 ! NF stage 17 [Term] id: XAO:0000059 name: pronephros is_obsolete: true replaced_by: XAO:0002000 [Term] id: XAO:0000061 name: pronephric capsule is_obsolete: true consider: XAO:0000318 [Term] id: XAO:0000062 name: nephrostome relationship: develops_from XAO:0000264 ! pronephric mesenchyme relationship: end_stage XAO:1000071 ! NF stage 59 relationship: part_of XAO:0002000 ! pronephric kidney relationship: start_stage XAO:1000045 ! NF stage 29 and 30 [Term] id: XAO:0000063 name: pronephric duct xref: ZFA:0000150 relationship: develops_from XAO:0000264 ! pronephric mesenchyme relationship: part_of XAO:0002000 ! pronephric kidney relationship: start_stage XAO:1000045 ! NF stage 29 and 30 [Term] id: XAO:0000064 name: heart def: "Internal, blood pumping organ ultimately composed of three chambers (two atria and one ventricle) and occupying a ventral position within the chest of the mature tadpole/frog." [PMID:17194606 "Warkman AS and Krieg PA"] subset: frequent_anatomy_items xref: ZFA:0000114 is_a: XAO:0003034 ! viscus relationship: part_of XAO:0000100 ! cardiovascular system relationship: start_stage XAO:1000048 ! NF stage 33 and 34 [Term] id: XAO:0000065 name: myocardium synonym: "cardiac muscle" RELATED [] xref: ZFA:0001319 relationship: develops_from XAO:0000336 ! fused heart primordium relationship: part_of XAO:0000064 ! heart [Term] id: XAO:0000066 name: endocardium xref: ZFA:0001320 relationship: develops_from XAO:0000336 ! fused heart primordium relationship: part_of XAO:0000064 ! heart relationship: start_stage XAO:1000043 ! NF stage 27 [Term] id: XAO:0000067 name: blood island def: "Region located on the ventral surface of the developing embryo that is a site of hematopoiesis and that is analogous to the yolk sac blood islands of higher vertebrates." [PMID:9618755 "Huber TL and Zon LI"] synonym: "VBI" RELATED [] synonym: "ventral blood island" RELATED [] synonym: "ventral lateral plate mesoderm" BROAD [] xref: ZFA:0000094 relationship: develops_from XAO:0000311 ! lateral plate mesoderm relationship: part_of XAO:0000122 ! hematological system relationship: start_stage XAO:1000038 ! NF stage 22 [Term] id: XAO:0000068 name: marginal zone is_a: XAO:0003042 ! embryonic structure relationship: part_of XAO:0000113 ! embryo [Term] id: XAO:0000069 name: ventral marginal zone is_a: XAO:0000068 ! marginal zone [Term] id: XAO:0000070 name: ventro-lateral marginal zone is_a: XAO:0000068 ! marginal zone [Term] id: XAO:0000071 name: dorso-lateral marginal zone is_a: XAO:0000068 ! marginal zone [Term] id: XAO:0000072 name: dorsal marginal zone def: "Marginal zone that is a key embryonic tissue region of the early gastrula stage embryo and that houses the Spemann-Mangold organizer." [PMID:17368611 "Papan C et al."] synonym: "DMZ" EXACT [PMID:17368611 "Papan C et al."] synonym: "organizer" RELATED [] is_a: XAO:0000068 ! marginal zone [Term] id: XAO:0000073 name: deep (mesenchymal) layer is_obsolete: true [Term] id: XAO:0000074 name: involuting marginal zone is_a: XAO:0000068 ! marginal zone [Term] id: XAO:0000075 name: involuting marginal zone mesenchymal layer synonym: "deep involuting marginal zone" RELATED [] relationship: part_of XAO:0000074 ! involuting marginal zone [Term] id: XAO:0000076 name: involuting marginal zone epithelial layer synonym: "superficial involuting marginal zone" RELATED [] relationship: part_of XAO:0000074 ! involuting marginal zone [Term] id: XAO:0000077 name: bottle cell def: "Cell type that is first to migrate inwards at the blastopore during gastrulation." [OMD:bottle+cell "CancerWeb Online Medical Dictionary"] is_a: XAO:0003012 ! cell relationship: part_of XAO:0000090 ! endoderm relationship: start_stage XAO:1000020 ! NF stage 10 [Term] id: XAO:0000078 name: blastopore lip relationship: part_of XAO:0000208 ! blastopore [Term] id: XAO:0000079 name: prechordal plate synonym: "head mesenchyme" BROAD [] synonym: "head mesoderm" BROAD [] xref: ZFA:0000060 is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000050 ! mesoderm relationship: start_stage XAO:1000030 ! NF stage 10.25 [Term] id: XAO:0000080 name: forelimb region subset: anatomical_site_slim is_a: XAO:0003186 ! anatomical region [Term] id: XAO:0000081 name: hindlimb region subset: anatomical_site_slim is_a: XAO:0003186 ! anatomical region [Term] id: XAO:0000082 name: circumblastoporal collar synonym: "circumblastoporal region" RELATED [] is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000050 ! mesoderm [Term] id: XAO:0000083 name: involuted dorsal mesoderm relationship: part_of XAO:0000082 ! circumblastoporal collar [Term] id: XAO:0000084 name: involuted ventral mesoderm relationship: part_of XAO:0000082 ! circumblastoporal collar [Term] id: XAO:0000085 name: intermediate mesoderm synonym: "lateral plate mesoderm" RELATED [] xref: ZFA:0001206 is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000050 ! mesoderm [Term] id: XAO:0000086 name: ciliary marginal zone xref: ZFA:0001289 relationship: part_of XAO:0000179 ! eye [Term] id: XAO:0000087 name: tail region subset: anatomical_site_slim is_a: XAO:0003186 ! anatomical region [Term] id: XAO:0000088 name: upper blastopore lip synonym: "dorsal blastopore lip" RELATED [] relationship: part_of XAO:0000078 ! blastopore lip [Term] id: XAO:0000089 name: lower blastopore lip synonym: "ventral blastopore lip" RELATED [] relationship: part_of XAO:0000078 ! blastopore lip [Term] id: XAO:0000090 name: endoderm def: "Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut." [OMD:endoderm "CancerWeb Online Medical Dictionary"] subset: frequent_anatomy_items synonym: "entoderm" RELATED [] xref: ZFA:0000017 is_a: XAO:0003011 ! primary germ layer [Term] id: XAO:0000091 name: head endoderm relationship: part_of XAO:0000090 ! endoderm [Term] id: XAO:0000092 name: archenteron def: "The cavity of the gastrula forming a primitive gut. At NF stage 20-21 its wide canal becomes dorso-ventrally compressed and narrowed in the future trunk region so that a subdivision into a foregut, a midgut and a hindgut with protruding endodermal mass becomes manifest." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 39)", NLM:archenteron "MedlinePlus Medical Dictionary"] is_a: XAO:0003190 ! anatomical space relationship: part_of XAO:0000090 ! endoderm relationship: start_stage XAO:1000030 ! NF stage 10.25 [Term] id: XAO:0000093 name: archenteron floor relationship: part_of XAO:0000092 ! archenteron [Term] id: XAO:0000094 name: archenteron roof relationship: part_of XAO:0000092 ! archenteron relationship: start_stage XAO:1000022 ! NF stage 12 [Term] id: XAO:0000095 name: lateral line system def: "Sensory system that has as it parts the sense organs that detect vibrations carried through water, develops during late tailbud stage, and persists in the adult bearing elaborate dorsal and ventral components." [ISBN:0471209627 "Deuchar EM (pg. 23-24)", ISBN:0815318960 "Nieuwkoop and Faber (pg. 47)"] synonym: "lateral line stitches" RELATED [] synonym: "lateral-line organs" RELATED [] xref: ZFA:0000034 is_a: XAO:0003194 ! sensory system relationship: part_of XAO:0000178 ! peripheral nervous system relationship: start_stage XAO:1000048 ! NF stage 33 and 34 [Term] id: XAO:0000096 name: pharyngeal arch def: "One of a series of bony or cartilaginous arches that develop in the walls of the mouth cavity and pharynx of the embryo." [NLM:branchial+arch "MedlinePlus Medical Dictionary"] subset: frequent_anatomy_items synonym: "pharyngeal arches" RELATED PLURAL [] synonym: "visceral arch" RELATED [] xref: ZFA:0001306 relationship: part_of XAO:0003024 ! head [Term] id: XAO:0000097 name: mandibular arch synonym: "first visceral arch" RELATED [] xref: ZFA:0001227 is_a: XAO:0000096 ! pharyngeal arch relationship: develops_from XAO:0000102 ! visceral pouch 1 relationship: part_of XAO:0003176 ! splanchnocranium relationship: start_stage XAO:1000040 ! NF stage 24 [Term] id: XAO:0000098 name: hyoid arch synonym: "second visceral arch" RELATED [] is_a: XAO:0000096 ! pharyngeal arch relationship: develops_from XAO:0000247 ! visceral pouch 2 relationship: start_stage XAO:1000040 ! NF stage 24 [Term] id: XAO:0000099 name: branchial arch synonym: "branchial arches" RELATED PLURAL [] is_a: XAO:0000096 ! pharyngeal arch relationship: start_stage XAO:1000043 ! NF stage 27 [Term] id: XAO:0000100 name: cardiovascular system def: "Anatomical system that has as its parts the heart and blood vessels." [BTO:0000088] xref: ZFA:0000010 is_a: XAO:0003002 ! anatomical system relationship: end_stage XAO:0000437 ! death [Term] id: XAO:0000101 name: liver diverticulum is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000232 ! foregut relationship: start_stage XAO:1000024 ! NF stage 14 [Term] id: XAO:0000102 name: visceral pouch 1 synonym: "first visceral pouch" EXACT [] is_a: XAO:0000282 ! visceral pouch relationship: start_stage XAO:1000036 ! NF stage 20 [Term] id: XAO:0000103 name: midgut is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000092 ! archenteron relationship: part_of XAO:0000125 ! alimentary system relationship: start_stage XAO:1000036 ! NF stage 20 [Term] id: XAO:0000104 name: hindgut is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000092 ! archenteron relationship: part_of XAO:0000125 ! alimentary system relationship: start_stage XAO:1000036 ! NF stage 20 [Term] id: XAO:0000105 name: pharyngeal cavity is_a: XAO:0003190 ! anatomical space relationship: develops_from XAO:0000232 ! foregut relationship: part_of XAO:0000125 ! alimentary system relationship: start_stage XAO:1000045 ! NF stage 29 and 30 [Term] id: XAO:0000106 name: post-anal gut relationship: part_of XAO:0000092 ! archenteron [Term] id: XAO:0000107 name: tail bud def: "Rapidly proliferating mass of cells at the caudal extremity of the embryo. Its formation is reflected in a caudal carving of the posterior portion of the archenteric canal at NF stage 22. With its further outgrowth, the postanal gut primordium becomes stretched. Its lumen is in broad communication with the hindgut at NF stage 25." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 42)", OMD:tail+bud "CancerWeb Online Medical Dictionary"] subset: frequent_anatomy_items synonym: "tailbud" EXACT [] xref: ZFA:0000077 is_a: XAO:0003042 ! embryonic structure relationship: start_stage XAO:1000041 ! NF stage 25 [Term] id: XAO:0000108 name: chordoneural hinge relationship: part_of XAO:0000107 ! tail bud [Term] id: XAO:0000109 name: posterior wall of NEC relationship: part_of XAO:0000107 ! tail bud [Term] id: XAO:0000110 name: glomeral mesenchyme def: "Portion of tissue that consists of the precursors of the pronephric glomus or glomerulus; derived from the medial portion of the pronephric intermediate mesoderm." [ISBN:0815318960 "Nieuwkoop and Faber"] synonym: "corpuscle" RELATED [] synonym: "glomerulus" RELATED [] is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000085 ! intermediate mesoderm [Term] id: XAO:0000111 name: germ cell def: "Cell type that is involved in the reproduction of the organism." [XB:curator "Xenbase"] xref: CL:0000586 is_a: XAO:0003148 ! germ line cell [Term] id: XAO:0000113 name: embryo def: "Anatomical entity that comprises the animal in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems." [BTO:0000379] subset: frequent_anatomy_items xref: ZFA:0000103 is_a: XAO:0000000 ! Xenopus anatomical entity relationship: develops_from XAO:0000035 ! zygote relationship: start_stage XAO:1000001 ! NF stage 1 [Term] id: XAO:0000114 name: artery def: "Any of the tubular branching vessels that carry blood from the heart through the body." [NLM:artery "MedlinePlus Medical Dictionary"] xref: ZFA:0000005 is_a: XAO:0001011 ! blood vessel [Term] id: XAO:0000115 name: vein def: "Any of the tubular branching vessels that carry blood from the capillaries toward the heart." [NLM:vein "MedlinePlus Medical Dictionary"] xref: ZFA:0000082 is_a: XAO:0001011 ! blood vessel [Term] id: XAO:0000116 name: capillary def: "Any of the smallest blood vessels connecting arterioles with venules." [NLM:capillary "MedlinePlus Medical Dictionary"] is_a: XAO:0001011 ! blood vessel [Term] id: XAO:0000117 name: respiratory system def: "Anatomical system that has as its parts the organs involved in breathing in respiration (breathing)." [OMD:respiratory+apparatus "CancerWeb Online Medical Dictionary"] xref: ZFA:0000272 is_a: XAO:0003002 ! anatomical system relationship: end_stage XAO:0000437 ! death [Term] id: XAO:0000118 name: trachea relationship: part_of XAO:0000117 ! respiratory system [Term] id: XAO:0000119 name: lung def: "Saccular thoracic organ that constitutes the basic respiratory organ." [BTO:0000763] is_a: XAO:0003034 ! viscus relationship: part_of XAO:0000117 ! respiratory system [Term] id: XAO:0000120 name: external gill is_a: XAO:0003028 ! surface structure relationship: develops_from XAO:0000448 ! gill primordium relationship: part_of XAO:0000117 ! respiratory system relationship: start_stage XAO:1000051 ! NF stage 39 [Term] id: XAO:0000121 name: bronchus relationship: part_of XAO:0000117 ! respiratory system [Term] id: XAO:0000122 name: hematological system def: "Anatomical system that consists of the blood and blood forming tissues." [OMD:haematological "CancerWeb Online Medical Dictionary"] synonym: "haematological system" EXACT [] synonym: "hematopoietic system" RELATED [] is_a: XAO:0003002 ! anatomical system relationship: end_stage XAO:0000437 ! death [Term] id: XAO:0000123 name: bone marrow relationship: part_of XAO:0000122 ! hematological system [Term] id: XAO:0000124 name: blood def: "The fluid that circulates in the heart, arteries, capillaries, and veins carrying nourishment and oxygen to and bringing away waste products from all parts of the animal." [NLM:blood "MedlinePlus Medical Dictionary"] xref: ZFA:0000007 relationship: part_of XAO:0000122 ! hematological system relationship: start_stage XAO:1000049 ! NF stage 35 and 36 [Term] id: XAO:0000125 name: alimentary system def: "Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes." [NLM:alimentary+system "MedlinePlus Medical Dictionary"] synonym: "digestive system" RELATED [] synonym: "gut" RELATED [] xref: ZFA:0000339 is_a: XAO:0003002 ! anatomical system relationship: end_stage XAO:0000437 ! death [Term] id: XAO:0000126 name: oral cavity xref: ZFA:0001027 is_a: XAO:0003190 ! anatomical space relationship: part_of XAO:0000125 ! alimentary system relationship: part_of XAO:0003029 ! mouth [Term] id: XAO:0000127 name: esophagus def: "Tube that connects the pharynx to the stomach. At NF stage 57 it is a straight tube, round in cross section, and starting from the pharynx runs backward along the dorsal side of the abdominal cavity. Its lining consists of a columnar glandular epithelium with mucus secreting cells. It is thrown into longitudinal folds." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 156)", OMD:esophagus "CancerWeb Online Medical Dictionary"] synonym: "oesophagus" EXACT [] xref: ZFA:0000204 relationship: part_of XAO:0000125 ! alimentary system [Term] id: XAO:0000128 name: stomach def: "Internal organ that is the dilated portion of the alimentary tract situated between the esophagus and the beginning of the duodenum. It produces gastric juices involved in the breakdown of food." [OMD:stomach "CancerWeb Online Medical Dictionary"] xref: ZFA:0000437 is_a: XAO:0003034 ! viscus relationship: develops_from XAO:0000232 ! foregut relationship: part_of XAO:0000125 ! alimentary system [Term] id: XAO:0000129 name: intestine xref: ZFA:0001338 is_a: XAO:0003034 ! viscus relationship: part_of XAO:0000125 ! alimentary system [Term] id: XAO:0000130 name: small intestine relationship: part_of XAO:0000129 ! intestine [Term] id: XAO:0000131 name: large intestine relationship: part_of XAO:0000129 ! intestine [Term] id: XAO:0000132 name: liver and biliary system xref: ZFA:0000036 relationship: part_of XAO:0000125 ! alimentary system [Term] id: XAO:0000133 name: liver def: "Vascular, glandular internal organ that secretes bile and causes important changes in many of the substances contained in the blood." [BTO:0000759] xref: ZFA:0000123 is_a: XAO:0003034 ! viscus relationship: part_of XAO:0000132 ! liver and biliary system relationship: start_stage XAO:1000049 ! NF stage 35 and 36 [Term] id: XAO:0000134 name: bile duct def: "Duct that carries bile from the liver to the small intestine." [ZFA:0001100] synonym: "hepatic duct" RELATED [] relationship: develops_from XAO:0000101 ! liver diverticulum relationship: part_of XAO:0000132 ! liver and biliary system [Term] id: XAO:0000135 name: gall bladder xref: ZFA:0000208 is_a: XAO:0003034 ! viscus relationship: develops_from XAO:0000101 ! liver diverticulum relationship: part_of XAO:0000132 ! liver and biliary system [Term] id: XAO:0000136 name: pancreas def: "Internal gland organ with distinct tissues with different endocrine and exocrine functions. Its rudiment has three parts, one dorsal and two ventral primordia. The ventral can be first detected at NF stage 37/38. The dorsal is clearly segregated from the duodenal wall by NF stage 39. At NF stage 40 the right and left primordia have fused just above the gasto-duodenal vein. At NF stage 42 blood vessels penetrate into the crevices between the pancreatic acini making them more conspicuous." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 154-5)", ISBN:0881679860 "Githens S"] xref: ZFA:0000140 is_a: XAO:0003034 ! viscus relationship: develops_from XAO:0001103 ! ventral pancreatic bud relationship: part_of XAO:0000125 ! alimentary system relationship: start_stage XAO:1000051 ! NF stage 39 [Term] id: XAO:0000137 name: exocrine pancreas def: "Pancreatic tissue composed of acinar epithelial cells and ductal epithelium that manufacture the proteolytic enzymes and bicarbonate required for digestion." [ZFA:0001249] xref: ZFA:0001249 relationship: part_of XAO:0000136 ! pancreas [Term] id: XAO:0000138 name: mesentery xref: ZFA:0005129 is_a: XAO:0003045 ! epithelium relationship: part_of XAO:0000125 ! alimentary system [Term] id: XAO:0000139 name: peritoneum xref: ZFA:0005120 is_a: XAO:0003045 ! epithelium relationship: part_of XAO:0000125 ! alimentary system [Term] id: XAO:0000140 name: urogenital system def: "Anatomical system that has as its parts the organs concerned with the production and excretion of urine and those concerned with reproduction." [NLM:genitourinary+tract "MedlinePlus Medical Dictionary"] is_a: XAO:0003002 ! anatomical system relationship: end_stage XAO:0000437 ! death [Term] id: XAO:0000141 name: mesonephric kidney def: "Organ that is the definitive adult kidney. It replaces the earlier pronephros, which degenerates as the mesonephros becomes functional in feeding stage tadpoles." [XB:curator "Xenbase"] synonym: "adult kidney" RELATED [] synonym: "mesonephros" RELATED [] synonym: "opisthonephros" RELATED [] relationship: part_of XAO:0000143 ! urinary system relationship: part_of XAO:0003025 ! trunk [Term] id: XAO:0000142 name: genital system def: "Anatomical system that has as its parts the organs concerned with reproduction." [NLM:genitourinary+tract "MedlinePlus Medical Dictionary"] synonym: "reproductive system" RELATED [] xref: ZFA:0000632 relationship: develops_from XAO:0000018 ! genital ridge relationship: part_of XAO:0000140 ! urogenital system [Term] id: XAO:0000143 name: urinary system def: "Anatomical system that has as its parts the organs concerned with the production and excretion of urine." [NLM:genitourinary+tract "MedlinePlus Medical Dictionary"] relationship: part_of XAO:0000140 ! urogenital system [Term] id: XAO:0000144 name: ureter relationship: part_of XAO:0000143 ! urinary system [Term] id: XAO:0000146 name: glomerulus synonym: "renal corpuscle" RELATED [] relationship: part_of XAO:0000292 ! mesonephric nephron [Term] id: XAO:0000147 name: glomerus is_a: XAO:0000146 ! glomerulus [Term] id: XAO:0000148 name: mesonephric tubule synonym: "renal tubule" RELATED [] relationship: part_of XAO:0000292 ! mesonephric nephron [Term] id: XAO:0000149 name: renal proximal convoluted tubule is_obsolete: true consider: XAO:0000331 [Term] id: XAO:0000150 name: loop of Henle is_obsolete: true [Term] id: XAO:0000151 name: mesonephric collecting duct relationship: part_of XAO:0000148 ! mesonephric tubule [Term] id: XAO:0000152 name: renal distal convoluted tubule is_obsolete: true consider: XAO:0000334 [Term] id: XAO:0000153 name: urethra relationship: part_of XAO:0000143 ! urinary system [Term] id: XAO:0000154 name: bladder is_a: XAO:0003034 ! viscus relationship: part_of XAO:0000143 ! urinary system relationship: start_stage XAO:1000067 ! NF stage 55 [Term] id: XAO:0000155 name: male genitalia def: "The organs of the male reproductive system." [NLM:genitalia "MedlinePlus Medical Dictionary"] synonym: "male genitals" RELATED PLURAL [] is_a: XAO:0000142 ! genital system relationship: part_of XAO:0003006 ! male organism [Term] id: XAO:0000156 name: female genitalia def: "The organs of the female reproductive system." [NLM:genitalia "MedlinePlus Medical Dictionary"] synonym: "female genitals" RELATED PLURAL [] is_a: XAO:0000142 ! genital system relationship: part_of XAO:0003005 ! female organism [Term] id: XAO:0000157 name: testis def: "Reproductive organ that produces and releases sperm." [XB:curator "Xenbase"] synonym: "testes" RELATED PLURAL [] xref: ZFA:0000598 is_a: XAO:0003146 ! gonad relationship: part_of XAO:0000155 ! male genitalia [Term] id: XAO:0000158 name: endocrine system def: "Anatomical system that consists of the glands and parts of glands that produce endocrine secretions and help to integrate and control bodily metabolic activity." [NLM:endocrine+system "MedlinePlus Medical Dictionary"] xref: ZFA:0001158 is_a: XAO:0003002 ! anatomical system relationship: end_stage XAO:0000437 ! death [Term] id: XAO:0000159 name: Islets of Langerhans synonym: "endocrine pancreas" RELATED [] relationship: develops_from XAO:0001103 ! ventral pancreatic bud relationship: part_of XAO:0000136 ! pancreas relationship: part_of XAO:0000158 ! endocrine system relationship: start_stage XAO:1000057 ! NF stage 45 [Term] id: XAO:0000160 name: pineal gland synonym: "epiphysis" RELATED [] synonym: "pineal organ" RELATED [] xref: ZFA:0000019 relationship: part_of XAO:0000014 ! midbrain relationship: part_of XAO:0000158 ! endocrine system relationship: part_of XAO:0003198 ! visual system relationship: start_stage XAO:1000042 ! NF stage 26 [Term] id: XAO:0000162 name: thyroid relationship: develops_from XAO:0000444 ! thyroid primordium relationship: part_of XAO:0000158 ! endocrine system relationship: start_stage XAO:1000061 ! NF stage 49 [Term] id: XAO:0000163 name: thymus def: "Anatomical structure of largely lymphoid tissue that functions in cell-mediated immunity by being the site where T cells develop." [NLM:thymus "MedlinePlus Medical Dictionary"] xref: ZFA:0001078 relationship: end_stage XAO:1000009 ! adult relationship: part_of XAO:0000158 ! endocrine system relationship: part_of XAO:0003152 ! immune system relationship: start_stage XAO:1000052 ! NF stage 40 [Term] id: XAO:0000164 name: adrenal gland relationship: part_of XAO:0000158 ! endocrine system [Term] id: XAO:0000165 name: adrenal cortex synonym: "interrenal tissue" RELATED [] relationship: part_of XAO:0000164 ! adrenal gland [Term] id: XAO:0000166 name: adrenal medulla synonym: "chromaffin cells" RELATED [] relationship: part_of XAO:0000164 ! adrenal gland [Term] id: XAO:0000167 name: parathyroid relationship: develops_from XAO:0000447 ! branchial arch 1 relationship: develops_from XAO:0000452 ! ultimobranchial body relationship: part_of XAO:0000158 ! endocrine system [Term] id: XAO:0000168 name: musculoskeletal system def: "Anatomical system that provides locomotion and physical support to the organism." [XB:curator "Xenbase"] is_a: XAO:0003002 ! anatomical system relationship: end_stage XAO:0000437 ! death [Term] id: XAO:0000169 name: bone def: "The hard form of connective tissue that constitutes the majority of the skeleton." [BTO:0000140] xref: ZFA:0001514 is_a: XAO:0001017 ! portion of connective tissue [Term] id: XAO:0000170 name: cartilage def: "A type of dense connective tissue that is composed of specialized cells, chondrocytes, that produce a large amount of extracellular matrix." [WIKI:Cartilage "Wikipedia (en)"] xref: ZFA:0001501 is_a: XAO:0001017 ! portion of connective tissue [Term] id: XAO:0000171 name: joint def: "Anatomical cluster that consists of two or more adjacent bones or cartilages, which may be interconnected by various types of tissue." [ZFA:0001596] xref: ZFA:0001596 is_a: XAO:0003160 ! anatomical cluster [Term] id: XAO:0000172 name: muscle def: "A body tissue consisting of long cells that contract when stimulated and produce motion." [BTO:0000887] subset: frequent_anatomy_items xref: ZFA:0005145 is_a: XAO:0003040 ! portion of tissue [Term] id: XAO:0000173 name: tendon alt_id: XAO:0000400 def: "A fibrous, strong, connective tissue that connects muscle to bone." [OMD:tendon "CancerWeb Online Medical Dictionary"] is_a: XAO:0001017 ! portion of connective tissue relationship: develops_from XAO:0000399 ! tendon fibroblast [Term] id: XAO:0000174 name: skeletal muscle def: "A type of muscle used to create movement, by applying force to bones and joints." [WIKI:Skeletal_muscle "Wikipedia (en)"] is_a: XAO:0000172 ! muscle relationship: develops_from XAO:0000315 ! myotome relationship: part_of XAO:0000168 ! musculoskeletal system relationship: start_stage XAO:1000058 ! NF stage 46 [Term] id: XAO:0000175 name: smooth muscle is_a: XAO:0000172 ! muscle relationship: develops_from XAO:0000311 ! lateral plate mesoderm [Term] id: XAO:0000176 name: dermal system def: "Anatomical system that consists of the skin and its appendages." [OMD:dermal+system "CancerWeb Online Medical Dictionary"] is_a: XAO:0003002 ! anatomical system relationship: end_stage XAO:0000437 ! death [Term] id: XAO:0000177 name: nervous system def: "Anatomical system that has as its parts the brain and spinal cord, nerves, ganglia, and parts of the receptor organs and that receives and interprets stimuli and transmits impulses to the effector organs." [NLM:nervous+system "MedlinePlus Medical Dictionary"] subset: frequent_anatomy_items xref: ZFA:0000396 is_a: XAO:0003002 ! anatomical system relationship: end_stage XAO:0000437 ! death [Term] id: XAO:0000178 name: peripheral nervous system def: "One of the two major divisions of the nervous system. Its nerves connect the central nervous system with sensory organs, other organs, muscles, blood vessels and glands." [OMD:peripheral+nervous+system "CancerWeb Online Medical Dictionary"] synonym: "PNS" EXACT [] xref: ZFA:0000142 relationship: part_of XAO:0000177 ! nervous system [Term] id: XAO:0000179 name: eye def: "The organ of sight (visual apparatus), almost spherical in shape. At the end of development (NF stage 66) the eyes bulge out of their orbital capsules near the lateral edge of the dorsal side of the head." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 80)", XB:curator "Xenbase"] subset: frequent_anatomy_items synonym: "eyes" RELATED PLURAL [] xref: ZFA:0000107 relationship: develops_from XAO:0000227 ! eye primordium relationship: part_of XAO:0000215 ! central nervous system relationship: part_of XAO:0003024 ! head relationship: part_of XAO:0003198 ! visual system [Term] id: XAO:0000180 name: cornea def: "The transparent front part of the eye that, together with the lens, refracts light." [WIKI:Cornea "Wikipedia (en)"] xref: ZFA:0000640 is_a: XAO:0003028 ! surface structure relationship: part_of XAO:0000179 ! eye [Term] id: XAO:0000181 name: globe relationship: part_of XAO:0000179 ! eye [Term] id: XAO:0000182 name: conjunctiva relationship: part_of XAO:0000179 ! eye [Term] id: XAO:0000183 name: sclera relationship: part_of XAO:0000179 ! eye [Term] id: XAO:0000185 name: iris xref: ZFA:0001238 relationship: develops_from XAO:0000228 ! eye vesicle relationship: part_of XAO:0000179 ! eye [Term] id: XAO:0000186 name: ciliary body xref: ZFA:0001203 relationship: part_of XAO:0000179 ! eye [Term] id: XAO:0000187 name: dorsolateral placode xref: ZFA:0001310 is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000320 ! sensorial layer relationship: start_stage XAO:1000038 ! NF stage 22 [Term] id: XAO:0000188 name: cranial nerve II def: "Cranial nerve that runs to the eye." [ISBN:0471209627 "Deuchar EM (pg. 29)"] synonym: "optic nerve" RELATED [] xref: ZFA:0000435 is_a: XAO:0003089 ! cranial nerve relationship: part_of XAO:0000179 ! eye relationship: start_stage XAO:1000048 ! NF stage 33 and 34 [Term] id: XAO:0000189 name: auditory apparatus relationship: develops_from XAO:0000006 ! otic vesicle relationship: part_of XAO:0003195 ! vestibuloauditory system [Term] id: XAO:0000190 name: external ear relationship: part_of XAO:0000189 ! auditory apparatus [Term] id: XAO:0000191 name: middle ear relationship: part_of XAO:0000189 ! auditory apparatus [Term] id: XAO:0000192 name: inner ear def: "Labyrinthine anatomical cluster that comprises sensory endorgans specialized for vestibular, auditory, and acoustico-vestibular sensation." [PMID:16217737 "Quick QA and Serrano EE"] xref: ZFA:0000217 is_a: XAO:0003160 ! anatomical cluster relationship: part_of XAO:0000189 ! auditory apparatus [Term] id: XAO:0000193 name: osseous labyrinth synonym: "bony labyrinth" RELATED [] relationship: part_of XAO:0000192 ! inner ear [Term] id: XAO:0000194 name: membranous labyrinth relationship: part_of XAO:0000192 ! inner ear [Term] id: XAO:0000195 name: utricle xref: ZFA:0000700 relationship: part_of XAO:0000194 ! membranous labyrinth [Term] id: XAO:0000196 name: sacculus synonym: "saccule" RELATED [] relationship: part_of XAO:0000194 ! membranous labyrinth [Term] id: XAO:0000197 name: lagena synonym: "cochlea" RELATED [] xref: ZFA:0000374 relationship: part_of XAO:0000193 ! osseous labyrinth [Term] id: XAO:0000198 name: semicircular canal xref: ZFA:0000431 relationship: part_of XAO:0000193 ! osseous labyrinth [Term] id: XAO:0000199 name: vestibule relationship: part_of XAO:0000193 ! osseous labyrinth [Term] id: XAO:0000200 name: animal blastomere def: "Pigmented, smaller blastomere of the animal (upper) hemisphere of the cleaving embryo." [ISBN:0471209627 "Deuchar EM (pg. 103)"] synonym: "micromere" RELATED [] is_a: XAO:0003016 ! blastomere relationship: develops_from XAO:0000202 ! animal hemisphere relationship: end_stage XAO:1000019 ! NF stage 9 relationship: start_stage XAO:1000011 ! NF stage 2 (2-cell) [Term] id: XAO:0000201 name: olfactory apparatus is_obsolete: true consider: XAO:0000273 [Term] id: XAO:0000202 name: animal hemisphere relationship: part_of XAO:0000035 ! zygote relationship: start_stage XAO:1000001 ! NF stage 1 [Term] id: XAO:0000203 name: archencephalic region is_obsolete: true [Term] id: XAO:0000204 name: peripheral nerve is_a: XAO:0003047 ! nerve relationship: part_of XAO:0000178 ! peripheral nervous system [Term] id: XAO:0000205 name: axial mesoderm xref: ZFA:0001204 is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000050 ! mesoderm [Term] id: XAO:0000206 name: blastocoel anlage relationship: part_of XAO:0000035 ! zygote [Term] id: XAO:0000207 name: blastocoel roof relationship: part_of XAO:0000294 ! blastocoel [Term] id: XAO:0000208 name: blastopore relationship: part_of XAO:0000068 ! marginal zone [Term] id: XAO:0000209 name: ganglion def: "Portion of tissue that contains cell bodies of neurons and is located outside the central nervous system." [NLM:ganglion "MedlinePlus Medical Dictionary"] synonym: "ganglia" RELATED PLURAL [] xref: ZFA:0000190 is_a: XAO:0003040 ! portion of tissue relationship: part_of XAO:0000178 ! peripheral nervous system [Term] id: XAO:0000210 name: spinal ganglion is_a: XAO:0000209 ! ganglion relationship: start_stage XAO:1000051 ! NF stage 39 [Term] id: XAO:0000211 name: sympathetic chain relationship: part_of XAO:0000178 ! peripheral nervous system [Term] id: XAO:0000212 name: tympanum relationship: part_of XAO:0000189 ! auditory apparatus [Term] id: XAO:0000213 name: auditory tube relationship: part_of XAO:0000189 ! auditory apparatus [Term] id: XAO:0000214 name: auditory ossicle relationship: part_of XAO:0000189 ! auditory apparatus [Term] id: XAO:0000215 name: central nervous system def: "The part of the nervous system that consists of the brain and spinal cord, to which sensory impulses are transmitted and from which motor impulses pass out, and that supervises and coordinates the activity of the entire nervous system." [NLM:central+nervous+system "MedlinePlus Medical Dictionary"] synonym: "CNS" EXACT [] xref: ZFA:0000012 relationship: part_of XAO:0000177 ! nervous system [Term] id: XAO:0000216 name: cortex relationship: part_of XAO:0000035 ! zygote [Term] id: XAO:0000217 name: dermis xref: ZFA:0001119 relationship: develops_from XAO:0000220 ! dermatome relationship: part_of XAO:0000023 ! skin [Term] id: XAO:0000218 name: appendage synonym: "appendages" RELATED PLURAL [] relationship: part_of XAO:0000023 ! skin [Term] id: XAO:0000219 name: superficial (epithelial) layer is_obsolete: true [Term] id: XAO:0000220 name: dermatome def: "Somitic compartment that is a precursor of dermis, the cells of which become arranged in a single layer that blankets the myotome, possibly continuously (unsegmented) across somites." [PMID:17313522 "Handrigan GR and Wassersug RJ"] is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000396 ! head somite 1 relationship: develops_from XAO:0000403 ! head somite 2 relationship: develops_from XAO:0000404 ! head somite 3 relationship: develops_from XAO:0000405 ! head somite 4 relationship: develops_from XAO:0000406 ! trunk somite 1 relationship: develops_from XAO:0000407 ! trunk somite 2 relationship: develops_from XAO:0000408 ! trunk somite 3 relationship: develops_from XAO:0000409 ! trunk somite 4 relationship: develops_from XAO:0000410 ! trunk somite 5 relationship: develops_from XAO:0000411 ! trunk somite 6 relationship: develops_from XAO:0000412 ! trunk somite 7 relationship: develops_from XAO:0000416 ! trunk somite 8 relationship: develops_from XAO:0000417 ! trunk somite 9 relationship: develops_from XAO:0000418 ! trunk somite 10 relationship: develops_from XAO:0000419 ! trunk somite 11 relationship: develops_from XAO:0000420 ! trunk somite 12 relationship: develops_from XAO:0000421 ! trunk somite 13 relationship: develops_from XAO:0000422 ! trunk somite 14 relationship: develops_from XAO:0000423 ! trunk somite 15 relationship: develops_from XAO:0000424 ! trunk somite 16 relationship: develops_from XAO:0000425 ! trunk somite 17 relationship: part_of XAO:0000058 ! somite [Term] id: XAO:0000221 name: deuterencephalic region is_obsolete: true [Term] id: XAO:0000222 name: ear placode is_obsolete: true replaced_by: XAO:0000223 [Term] id: XAO:0000223 name: otic placode def: "Invagination of thickened epithelium near the hindbrain that gives rise to a spherically shaped ear vesicle." [PMID:16217737 "Quick QA and Serrano EE"] synonym: "auditory placode" RELATED [] xref: ZFA:0000138 is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000320 ! sensorial layer relationship: start_stage XAO:1000037 ! NF stage 21 [Term] id: XAO:0000224 name: vegetal part, early involuting relationship: part_of XAO:0000074 ! involuting marginal zone [Term] id: XAO:0000225 name: trigeminal placode xref: ZFA:0000162 is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000187 ! dorsolateral placode [Term] id: XAO:0000226 name: equatorial belt relationship: part_of XAO:0000035 ! zygote [Term] id: XAO:0000227 name: eye primordium def: "First trace of the future visual apparatus. The eye primordia forming antero-lateral evaginations of the closing neural tube are originally massive formations into which only a slit-shaped extension of the neural groove penetrates at NF stage 18. At NF stage 19 they clearly segregate from the anterior portion of the neural tube." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 30)"] synonym: "eye anlage" RELATED [] is_a: XAO:0003043 ! primordium relationship: develops_from XAO:0000045 ! pre-chordal neural plate relationship: end_stage XAO:1000037 ! NF stage 21 relationship: start_stage XAO:1000034 ! NF stage 18 [Term] id: XAO:0000228 name: eye vesicle synonym: "optic cup" RELATED [] is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000227 ! eye primordium relationship: part_of XAO:0003198 ! visual system relationship: start_stage XAO:1000037 ! NF stage 21 [Term] id: XAO:0000229 name: fasciculated network of fibrils synonym: "coelomic envelope" BROAD [] relationship: part_of XAO:0000256 ! oocyte [Term] id: XAO:0000230 name: follicle cell def: "Cell type that forms a layer within an ovarian follicle that surrounds the oocyte." [OMD:follicle+cell "CancerWeb Online Medical Dictionary"] xref: CL:0000477 is_a: XAO:0003012 ! cell relationship: part_of XAO:0000258 ! ovary [Term] id: XAO:0000231 name: follicle layer relationship: part_of XAO:0000157 ! testis relationship: part_of XAO:0000258 ! ovary [Term] id: XAO:0000232 name: foregut is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000092 ! archenteron relationship: part_of XAO:0000125 ! alimentary system relationship: start_stage XAO:1000036 ! NF stage 20 [Term] id: XAO:0000233 name: germ plasm relationship: end_stage XAO:1000052 ! NF stage 40 relationship: part_of XAO:0000280 ! vegetal hemisphere relationship: start_stage XAO:1000001 ! NF stage 1 [Term] id: XAO:0000234 name: germinal vesicle synonym: "GV" EXACT [] relationship: part_of XAO:0000256 ! oocyte [Term] id: XAO:0000235 name: cardiac mesoderm def: "Two migratory heart primordia that move ventrally during the course of neurulation, and whose fusion begins at the ventral midline at NF stage 16." [XB:curator "Xenbase"] synonym: "heart primordia" RELATED [] is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000050 ! mesoderm [Term] id: XAO:0000236 name: duodenum def: "The first part of the small intestine. At the junction of the stomach and the duodenum the alimentary canal is inflected. The duodenum first goes anteriorly for a short distance, turns dorsally, and eventually caudally, thus it is a U-shaped structure with two horizontal sections (a ventral and a dorsal one)." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 156)"] xref: ZFA:0000348 relationship: part_of XAO:0000130 ! small intestine [Term] id: XAO:0000237 name: ileum relationship: part_of XAO:0000130 ! small intestine [Term] id: XAO:0000238 name: rectum relationship: part_of XAO:0000131 ! large intestine [Term] id: XAO:0000239 name: hepato-pancreatic duct relationship: develops_from XAO:0000101 ! liver diverticulum relationship: part_of XAO:0000132 ! liver and biliary system [Term] id: XAO:0000240 name: lens placode xref: ZFA:0000122 is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000320 ! sensorial layer relationship: end_stage XAO:1000048 ! NF stage 33 and 34 relationship: start_stage XAO:1000043 ! NF stage 27 [Term] id: XAO:0000241 name: posterior cardinal vein xref: ZFA:0000477 is_a: XAO:0000115 ! vein relationship: develops_from XAO:0000052 ! cardinal vein [Term] id: XAO:0000242 name: mesonephric duct synonym: "Wolffian duct" RELATED [] xref: ZFA:0000546 relationship: develops_from XAO:0000063 ! pronephric duct relationship: part_of XAO:0000140 ! urogenital system [Term] id: XAO:0000243 name: colon relationship: part_of XAO:0000131 ! large intestine [Term] id: XAO:0000244 name: cloaca subset: frequent_anatomy_items synonym: "cloacal chamber" RELATED [] relationship: part_of XAO:0000107 ! tail bud relationship: part_of XAO:0000125 ! alimentary system relationship: start_stage XAO:1000044 ! NF stage 28 [Term] id: XAO:0000245 name: mitochondrial aggregate relationship: part_of XAO:0000256 ! oocyte [Term] id: XAO:0000246 name: myocoelic slit relationship: part_of XAO:0000315 ! myotome [Term] id: XAO:0000247 name: visceral pouch 2 synonym: "second visceral pouch" EXACT [] is_a: XAO:0000282 ! visceral pouch relationship: start_stage XAO:1000036 ! NF stage 20 [Term] id: XAO:0000248 name: neural groove def: "The median dorsal longitudinal groove formed in the embryo by the neural plate after the appearance of the neural folds." [NLM:neural+groove "MedlinePlus Medical Dictionary"] relationship: part_of XAO:0000249 ! neural plate [Term] id: XAO:0000249 name: neural plate def: "A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube. At NF stage 11.5 is the first indication of neural plate within the sensorial layer of ectoderm. It extends to near the animal pole by NF stage 12.5 and the entire plate is faintly delimited by NF stage 13." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 24-29)", OMD:neural+plate "CancerWeb Online Medical Dictionary"] xref: ZFA:0000132 relationship: part_of XAO:0000042 ! neuroectoderm relationship: start_stage XAO:1000032 ! NF stage 11.5 [Term] id: XAO:0000250 name: posterior neural tube xref: ZFA:0007037 relationship: develops_from XAO:0000046 ! chordal neural plate relationship: part_of XAO:0003204 ! neural tube relationship: start_stage XAO:1000036 ! NF stage 20 [Term] id: XAO:0000251 name: visceral pouch 3 synonym: "third visceral pouch" EXACT [] is_a: XAO:0000282 ! visceral pouch relationship: start_stage XAO:1000039 ! NF stage 23 [Term] id: XAO:0000252 name: neurocoel relationship: part_of XAO:0000042 ! neuroectoderm [Term] id: XAO:0000253 name: non-involuting marginal zone is_a: XAO:0000068 ! marginal zone relationship: part_of XAO:0000001 ! ectoderm [Term] id: XAO:0000254 name: visceral pouch 4 synonym: "fourth visceral pouch" EXACT [] is_a: XAO:0000282 ! visceral pouch relationship: start_stage XAO:1000041 ! NF stage 25 [Term] id: XAO:0000255 name: visceral pouch 5 synonym: "fifth visceral pouch" EXACT [] is_a: XAO:0000282 ! visceral pouch [Term] id: XAO:0000256 name: oocyte def: "The developing female gamete, the differentiation of which is classified into six stages: I (pre-vitellogenic), II (early vitellogenic), III (mid-vitellogenic, formation of pigment), IV (polarization along animal-vegetal axis), V (late vitellogenic), and VI (post-vitellogenic, appearance of equatorial band)." [PMID:4109871 "Dumont JN"] xref: CL:0000023 is_a: XAO:0000111 ! germ cell relationship: develops_from XAO:0000268 ! secondary oogonium [Term] id: XAO:0000257 name: oral evagination is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000232 ! foregut relationship: start_stage XAO:1000036 ! NF stage 20 [Term] id: XAO:0000258 name: ovary def: "Reproductive organ that produces and releases eggs." [XB:curator "Xenbase"] xref: ZFA:0000403 is_a: XAO:0003146 ! gonad relationship: part_of XAO:0000156 ! female genitalia [Term] id: XAO:0000259 name: paraxial mesoderm def: "Area of mesoderm at either side of the midline embryonic notochord that, on segmentation, forms the paired somites." [OMD:paraxial+mesoderm "CancerWeb Online Medical Dictionary"] xref: ZFA:0000255 is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000050 ! mesoderm relationship: start_stage XAO:1000023 ! NF stage 13 [Term] id: XAO:0000260 name: perivitelline space relationship: part_of XAO:0000035 ! zygote [Term] id: XAO:0000261 name: pigment layer relationship: part_of XAO:0000179 ! eye relationship: start_stage XAO:1000047 ! NF stage 32 [Term] id: XAO:0000262 name: polar body relationship: part_of XAO:0000256 ! oocyte [Term] id: XAO:0000263 name: primary oogonium synonym: "primary oogonia" RELATED PLURAL [] is_a: XAO:0000111 ! germ cell relationship: develops_from XAO:0003149 ! primordial germ cell relationship: part_of XAO:0000258 ! ovary relationship: start_stage XAO:1000066 ! NF stage 54 [Term] id: XAO:0000264 name: pronephric mesenchyme def: "Portion of tissue that consists of the mesenchymal precursor to the pronephric kidney and that begins to separate from the intermediate mesoderm at NF stage 21 and epithelializes by NF stage 30." [XB:curator "Xenbase"] synonym: "pronephric anlage" RELATED [] synonym: "pronephric bulge" RELATED [] synonym: "pronephric primordium" RELATED [] is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000085 ! intermediate mesoderm relationship: end_stage XAO:1000045 ! NF stage 29 and 30 relationship: start_stage XAO:1000037 ! NF stage 21 [Term] id: XAO:0000265 name: visceral pouch 6 synonym: "sixth visceral pouch" EXACT [] is_a: XAO:0000282 ! visceral pouch [Term] id: XAO:0000266 name: retinal layer relationship: develops_from XAO:0000009 ! retina relationship: part_of XAO:0000179 ! eye relationship: start_stage XAO:1000044 ! NF stage 28 [Term] id: XAO:0000267 name: hypophyseal primordium is_a: XAO:0003043 ! primordium relationship: develops_from XAO:0000032 ! stomodeal-hypophyseal primordium [Term] id: XAO:0000268 name: secondary oogonium synonym: "secondary oogonia" RELATED PLURAL [] is_a: XAO:0000111 ! germ cell relationship: develops_from XAO:0000263 ! primary oogonium [Term] id: XAO:0000269 name: mouth primordium is_a: XAO:0003043 ! primordium relationship: develops_from XAO:0000032 ! stomodeal-hypophyseal primordium relationship: start_stage XAO:1000044 ! NF stage 28 [Term] id: XAO:0000270 name: sensorial layer of neurectoderm synonym: "deep layer of neurectoderm" RELATED [] relationship: part_of XAO:0000042 ! neuroectoderm [Term] id: XAO:0000271 name: somatic layer of lateral plate mesoderm is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000311 ! lateral plate mesoderm [Term] id: XAO:0000272 name: Jacobson's organ def: "An auxiliary olfactory sense organ involved in the detection of pheromones." [WIKI:Vomeronasal_organ "Wikipedia (en)"] synonym: "organon vomeronasale" EXACT [] synonym: "VNO" EXACT [] synonym: "vomeronasal organ" EXACT [] relationship: develops_from XAO:0000273 ! olfactory organ relationship: part_of XAO:0003196 ! olfactory system relationship: start_stage XAO:1000050 ! NF stage 37 and 38 [Term] id: XAO:0000273 name: olfactory organ relationship: develops_from XAO:0000005 ! olfactory placode relationship: part_of XAO:0003196 ! olfactory system relationship: start_stage XAO:1000050 ! NF stage 37 and 38 [Term] id: XAO:0000274 name: sperm entry point relationship: part_of XAO:0000035 ! zygote [Term] id: XAO:0000275 name: nasal pit is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000005 ! olfactory placode relationship: start_stage XAO:1000045 ! NF stage 29 and 30 [Term] id: XAO:0000276 name: splanchnic layer of lateral plate mesoderm is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000311 ! lateral plate mesoderm [Term] id: XAO:0000277 name: choana synonym: "choanae" RELATED PLURAL [] relationship: develops_from XAO:0000005 ! olfactory placode relationship: part_of XAO:0003024 ! head relationship: start_stage XAO:1000055 ! NF stage 43 [Term] id: XAO:0000278 name: animal part, late involuting relationship: part_of XAO:0000074 ! involuting marginal zone [Term] id: XAO:0000279 name: vegetal blastomere def: "Unpigmented, larger blastomere of the vegetal (lower) hemisphere of the cleaving embryo." [ISBN:0471209627 "Deuchar EM (pg. 103)"] synonym: "macromere" RELATED [] is_a: XAO:0003016 ! blastomere relationship: develops_from XAO:0000280 ! vegetal hemisphere relationship: end_stage XAO:1000019 ! NF stage 9 relationship: start_stage XAO:1000011 ! NF stage 2 (2-cell) [Term] id: XAO:0000280 name: vegetal hemisphere relationship: part_of XAO:0000035 ! zygote relationship: start_stage XAO:1000001 ! NF stage 1 [Term] id: XAO:0000281 name: vegetal yolk mass relationship: part_of XAO:0000280 ! vegetal hemisphere [Term] id: XAO:0000282 name: visceral pouch synonym: "visceral pouches" RELATED PLURAL [] is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000232 ! foregut [Term] id: XAO:0000283 name: pupil xref: ZFA:0001283 relationship: part_of XAO:0000179 ! eye [Term] id: XAO:0000284 name: epibranchial placode xref: ZFA:0001294 is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000187 ! dorsolateral placode relationship: develops_from XAO:0000320 ! sensorial layer [Term] id: XAO:0000285 name: pronephric nephron relationship: end_stage XAO:1000076 ! NF stage 64 relationship: part_of XAO:0002000 ! pronephric kidney relationship: start_stage XAO:1000045 ! NF stage 29 and 30 [Term] id: XAO:0000286 name: late proximal tubule relationship: part_of XAO:0000285 ! pronephric nephron [Term] id: XAO:0000287 name: early distal tubule relationship: part_of XAO:0000285 ! pronephric nephron [Term] id: XAO:0000288 name: early proximal tubule relationship: part_of XAO:0000285 ! pronephric nephron [Term] id: XAO:0000289 name: late distal segment relationship: part_of XAO:0000285 ! pronephric nephron [Term] id: XAO:0000290 name: pronephric nephron segment S1 is_obsolete: true [Term] id: XAO:0000291 name: mesonephric mesenchyme is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000085 ! intermediate mesoderm relationship: start_stage XAO:1000055 ! NF stage 43 [Term] id: XAO:0000292 name: mesonephric nephron alt_id: XAO:0000145 def: "The basic functional unit of the kidney." [PMID:9268568 "Vize PD et al."] synonym: "nephron" RELATED [] relationship: develops_from XAO:0000291 ! mesonephric mesenchyme relationship: part_of XAO:0000141 ! mesonephric kidney [Term] id: XAO:0000293 name: neural fold is_obsolete: true consider: XAO:0000310 [Term] id: XAO:0000294 name: blastocoel is_a: XAO:0003190 ! anatomical space relationship: develops_from XAO:0000206 ! blastocoel anlage [Term] id: XAO:0000295 name: central endoderm synonym: "vegetal endodermal core" RELATED [] relationship: part_of XAO:0000090 ! endoderm [Term] id: XAO:0000296 name: vegetal subset: anatomical_site_slim is_a: XAO:0003185 ! anatomical direction [Term] id: XAO:0000297 name: animal subset: anatomical_site_slim is_a: XAO:0003185 ! anatomical direction [Term] id: XAO:0000298 name: dorsal subset: anatomical_site_slim is_a: XAO:0003185 ! anatomical direction [Term] id: XAO:0000299 name: ventral subset: anatomical_site_slim is_a: XAO:0003185 ! anatomical direction [Term] id: XAO:0000300 name: superficial subset: anatomical_site_slim is_a: XAO:0003185 ! anatomical direction [Term] id: XAO:0000301 name: deep subset: anatomical_site_slim is_a: XAO:0003185 ! anatomical direction [Term] id: XAO:0000302 name: dorso-lateral subset: anatomical_site_slim is_a: XAO:0003185 ! anatomical direction [Term] id: XAO:0000303 name: ventro-lateral subset: anatomical_site_slim is_a: XAO:0003185 ! anatomical direction [Term] id: XAO:0000304 name: lateral subset: anatomical_site_slim is_a: XAO:0003185 ! anatomical direction [Term] id: XAO:0000305 name: cranial placode synonym: "cranial placodes" RELATED PLURAL [] is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000037 ! animal cap inner layer relationship: develops_from XAO:0000320 ! sensorial layer relationship: part_of XAO:0000001 ! ectoderm [Term] id: XAO:0000306 name: floor plate def: "Organizing center consisting of a small group of cells located at the ventral midline of the neural tube that influences the development of the nervous system, governing the specification of neuronal cell types and directing axonal trajectories." [GO:0021508, PMID:15738958 "Placzek M and Briscoe J"] synonym: "floorplate" EXACT [] synonym: "spinal cord floor" RELATED [] xref: ZFA:0000022 relationship: develops_from XAO:0000047 ! notoplate relationship: part_of XAO:0000020 ! spinal cord [Term] id: XAO:0000307 name: anterior neural tube xref: ZFA:0007038 relationship: develops_from XAO:0000045 ! pre-chordal neural plate relationship: part_of XAO:0003204 ! neural tube relationship: start_stage XAO:1000036 ! NF stage 20 [Term] id: XAO:0000309 name: marginal zone (sensu neural) subset: anatomical_site_slim is_a: XAO:0003186 ! anatomical region [Term] id: XAO:0000310 name: anterior neural fold relationship: part_of XAO:0000045 ! pre-chordal neural plate [Term] id: XAO:0000311 name: lateral plate mesoderm xref: ZFA:0000121 is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000050 ! mesoderm [Term] id: XAO:0000313 name: head somite def: "Any of the transient, degenerating occipital somites." [XB:curator "Xenbase"] synonym: "cranial somite" RELATED [] synonym: "occipital somite" RELATED [] is_a: XAO:0000058 ! somite relationship: start_stage XAO:1000027 ! NF stage 17 [Term] id: XAO:0000314 name: trunk somite is_a: XAO:0000058 ! somite relationship: part_of XAO:0003025 ! trunk [Term] id: XAO:0000315 name: myotome def: "Somitic compartment that is a precursor of muscle." [PMID:17313522 "Handrigan GR and Wassersug RJ"] synonym: "myotomes" RELATED PLURAL [] xref: ZFA:0001056 is_a: XAO:0003042 ! embryonic structure relationship: part_of XAO:0000058 ! somite [Term] id: XAO:0000316 name: epicardium xref: ZFA:0005057 relationship: develops_from XAO:0000336 ! fused heart primordium relationship: part_of XAO:0000064 ! heart [Term] id: XAO:0000318 name: glomus def: "The filtration unit of the pronephric kidney." [PMID:9268568 "Vize PD et al."] comment: Properly called a glomus as it extends over multiple body segments. synonym: "corpuscle" RELATED [] synonym: "glomera" RELATED PLURAL [] synonym: "glomerulus" RELATED [] relationship: develops_from XAO:0000110 ! glomeral mesenchyme relationship: end_stage XAO:1000067 ! NF stage 55 relationship: part_of XAO:0002000 ! pronephric kidney relationship: start_stage XAO:1000045 ! NF stage 29 and 30 [Term] id: XAO:0000319 name: trunk neural crest def: "Trunk portion of the neural crest. The anterior and middle regions of the neural crest segregate at NF stage 16, while the posterior portion forms at NF stage 17." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 30)"] synonym: "trunk crest" RELATED [] xref: ZFA:0001024 relationship: end_stage XAO:1000046 ! NF stage 31 relationship: part_of XAO:0000048 ! neural crest relationship: start_stage XAO:1000026 ! NF stage 16 [Term] id: XAO:0000320 name: sensorial layer def: "The inner layer of ectoderm." [XB:curator "Xenbase"] is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000001 ! ectoderm [Term] id: XAO:0000323 name: profundus ganglion synonym: "cranial ganglion" RELATED [] synonym: "profundus ganglia" RELATED PLURAL [] is_a: XAO:0000209 ! ganglion relationship: develops_from XAO:0000225 ! trigeminal placode [Term] id: XAO:0000324 name: hypobranchial placode def: "Derivative of ectodermal thickening ventral to second and third pharyngeal pouches. Gives rise to neurons of unknown fate." [PMID:12712315 "Schlosser G"] is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000187 ! dorsolateral placode [Term] id: XAO:0000326 name: left spleen primordium def: "Primordium of the spleen, which goes on to form the spleen proper, while the right splenic promordium degenerates." [XB:curator "Xenbase"] is_a: XAO:0003043 ! primordium relationship: develops_from XAO:0000276 ! splanchnic layer of lateral plate mesoderm [Term] id: XAO:0000327 name: right spleen primordium def: "Transient splenic primordia that degenerates by NF stage 40." [XB:curator "Xenbase"] is_a: XAO:0003043 ! primordium relationship: develops_from XAO:0000276 ! splanchnic layer of lateral plate mesoderm [Term] id: XAO:0000328 name: spleen def: "Internal lymphoid organ derived from left spleen primordia beginning at NF stage 48." [XB:curator "Xenbase"] xref: ZFA:0000436 is_a: XAO:0003034 ! viscus relationship: develops_from XAO:0000326 ! left spleen primordium relationship: part_of XAO:0003152 ! immune system relationship: start_stage XAO:1000060 ! NF stage 48 [Term] id: XAO:0000329 name: coelomic epithelium def: "The epithelial lining of the coelom." [XB:curator "Xenbase"] is_a: XAO:0003045 ! epithelium relationship: develops_from XAO:0000271 ! somatic layer of lateral plate mesoderm relationship: develops_from XAO:0000276 ! splanchnic layer of lateral plate mesoderm [Term] id: XAO:0000330 name: Mullerian duct relationship: develops_from XAO:0000085 ! intermediate mesoderm relationship: part_of XAO:0000140 ! urogenital system [Term] id: XAO:0000331 name: mesonephric early proximal tubule def: "Structure that is equivalent to the convoluted proximal tubule of metanephric nephrons." [XB:curator "Xenbase"] relationship: develops_from XAO:0000292 ! mesonephric nephron relationship: part_of XAO:0000148 ! mesonephric tubule [Term] id: XAO:0000332 name: mesonephric late proximal tubule def: "Structure that is the mesonephros nephron's equivalent to the straight proximal segment of a metanephric nephron." [XB:curator "Xenbase"] synonym: "opisthonephros" RELATED [] synonym: "proximal straight segment" RELATED [] relationship: develops_from XAO:0000292 ! mesonephric nephron relationship: part_of XAO:0000148 ! mesonephric tubule [Term] id: XAO:0000333 name: mesonephric early distal tubule def: "The mesonephric equivalent of the ascending limb, or straight distal segment, of metanephric nephrons." [XB:curator "Xenbase"] synonym: "ascending limb" RELATED [] synonym: "straight distal segment" RELATED [] relationship: develops_from XAO:0000292 ! mesonephric nephron relationship: part_of XAO:0000148 ! mesonephric tubule [Term] id: XAO:0000334 name: mesonephric late distal segment def: "The site of bicarbonate resorption in the adult kidney. It is equivalent to the convoluted distal segment of metanephric nephrons." [XB:curator "Xenbase"] relationship: develops_from XAO:0000292 ! mesonephric nephron relationship: part_of XAO:0000148 ! mesonephric tubule [Term] id: XAO:0000336 name: fused heart primordium synonym: "heart primordium" RELATED [] is_a: XAO:0003043 ! primordium relationship: develops_from XAO:0000235 ! cardiac mesoderm relationship: part_of XAO:0000100 ! cardiovascular system relationship: start_stage XAO:1000035 ! NF stage 19 [Term] id: XAO:0000337 name: endocardial tube is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000066 ! endocardium [Term] id: XAO:0000338 name: ventral aorta xref: ZFA:0000604 is_a: XAO:0003010 ! aorta relationship: develops_from XAO:0000337 ! endocardial tube [Term] id: XAO:0000339 name: left channel of ventral aorta is_a: XAO:0000114 ! artery relationship: develops_from XAO:0000338 ! ventral aorta [Term] id: XAO:0000340 name: right channel of ventral aorta is_a: XAO:0000114 ! artery relationship: develops_from XAO:0000338 ! ventral aorta [Term] id: XAO:0000341 name: aortic arch synonym: "aortic arches" RELATED PLURAL [] xref: ZFA:0005004 is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000339 ! left channel of ventral aorta relationship: develops_from XAO:0000340 ! right channel of ventral aorta [Term] id: XAO:0000342 name: aortic arch 1 synonym: "first aortic arch" EXACT [] is_a: XAO:0000341 ! aortic arch relationship: start_stage XAO:1000046 ! NF stage 31 [Term] id: XAO:0000343 name: aortic arch 2 synonym: "second aortic arch" EXACT [] is_a: XAO:0000341 ! aortic arch [Term] id: XAO:0000344 name: aortic arch 3 synonym: "third aortic arch" EXACT [] is_a: XAO:0000341 ! aortic arch relationship: start_stage XAO:1000047 ! NF stage 32 [Term] id: XAO:0000345 name: external carotid artery is_a: XAO:0000114 ! artery relationship: develops_from XAO:0000342 ! aortic arch 1 [Term] id: XAO:0000349 name: larval aorta is_a: XAO:0000114 ! artery relationship: develops_from XAO:0000051 ! dorsal aorta relationship: develops_from XAO:0000344 ! aortic arch 3 [Term] id: XAO:0000351 name: secondary vessel is_obsolete: true [Term] id: XAO:0000352 name: aortic arch 5 synonym: "fifth aortic arch" EXACT [] is_a: XAO:0000341 ! aortic arch relationship: start_stage XAO:1000049 ! NF stage 35 and 36 [Term] id: XAO:0000353 name: aortic arch 6 synonym: "sixth aortic arch" EXACT [] is_a: XAO:0000341 ! aortic arch relationship: start_stage XAO:1000049 ! NF stage 35 and 36 [Term] id: XAO:0000354 name: posterior palatine artery is_a: XAO:0000114 ! artery relationship: develops_from XAO:0000342 ! aortic arch 1 [Term] id: XAO:0000355 name: aortic arch 4 synonym: "fourth aortic arch" EXACT [] is_a: XAO:0000341 ! aortic arch relationship: start_stage XAO:1000048 ! NF stage 33 and 34 [Term] id: XAO:0000356 name: vascular endothelium synonym: "angioblasts" RELATED [] synonym: "vascular endothelia" RELATED PLURAL [] is_a: XAO:0003045 ! epithelium relationship: develops_from XAO:0000085 ! intermediate mesoderm relationship: part_of XAO:0000100 ! cardiovascular system [Term] id: XAO:0000357 name: arterial endothelium is_a: XAO:0003045 ! epithelium relationship: develops_from XAO:0000356 ! vascular endothelium relationship: part_of XAO:0000114 ! artery [Term] id: XAO:0000358 name: venous endothelium is_a: XAO:0003045 ! epithelium relationship: develops_from XAO:0000356 ! vascular endothelium relationship: part_of XAO:0000115 ! vein [Term] id: XAO:0000361 name: arteria iliaca communis is_a: XAO:0000114 ! artery relationship: develops_from XAO:0000051 ! dorsal aorta [Term] id: XAO:0000362 name: coeliaco-mesenteric artery is_a: XAO:0000114 ! artery relationship: develops_from XAO:0000051 ! dorsal aorta [Term] id: XAO:0000363 name: occipitovertebral artery is_a: XAO:0000114 ! artery relationship: develops_from XAO:0000051 ! dorsal aorta [Term] id: XAO:0000364 name: caudal artery xref: ZFA:0000011 is_a: XAO:0000114 ! artery relationship: develops_from XAO:0000051 ! dorsal aorta [Term] id: XAO:0000365 name: arteria subclavia is_a: XAO:0000114 ! artery relationship: develops_from XAO:0000363 ! occipitovertebral artery [Term] id: XAO:0000366 name: internal carotid artery xref: ZFA:0005081 is_a: XAO:0000114 ! artery relationship: develops_from XAO:0000051 ! dorsal aorta [Term] id: XAO:0000367 name: cerebral artery is_a: XAO:0000114 ! artery relationship: develops_from XAO:0000366 ! internal carotid artery [Term] id: XAO:0000368 name: opthalmic artery is_a: XAO:0000114 ! artery relationship: develops_from XAO:0000366 ! internal carotid artery [Term] id: XAO:0000369 name: anterior palatine artery is_a: XAO:0000114 ! artery relationship: develops_from XAO:0000366 ! internal carotid artery [Term] id: XAO:0000370 name: arteria mesenterica posterior is_a: XAO:0000114 ! artery relationship: develops_from XAO:0000361 ! arteria iliaca communis [Term] id: XAO:0000371 name: anterior lymph heart relationship: develops_from XAO:0000358 ! venous endothelium relationship: part_of XAO:0003199 ! lymphatic system relationship: start_stage XAO:1000047 ! NF stage 32 [Term] id: XAO:0000372 name: posterior lymph heart def: "Precursor to the lymph vessels, consisting of four pairs initially." [XB:curator "Xenbase"] relationship: develops_from XAO:0000358 ! venous endothelium relationship: part_of XAO:0003199 ! lymphatic system [Term] id: XAO:0000373 name: duct of Cuvier synonym: "common cardinal vein" RELATED [] is_a: XAO:0000115 ! vein relationship: develops_from XAO:0000358 ! venous endothelium [Term] id: XAO:0000374 name: dorsal lymph space relationship: develops_from XAO:0000371 ! anterior lymph heart relationship: part_of XAO:0003199 ! lymphatic system [Term] id: XAO:0000375 name: lymph vessel def: "A vessel that contains or conveys lymph." [BTO:0000752] synonym: "lymphatic vessel" RELATED [] xref: ZFA:0005105 relationship: develops_from XAO:0000372 ! posterior lymph heart relationship: develops_from XAO:0000374 ! dorsal lymph space relationship: part_of XAO:0001010 ! circulatory system relationship: part_of XAO:0003199 ! lymphatic system relationship: start_stage XAO:1000049 ! NF stage 35 and 36 [Term] id: XAO:0000376 name: omphalomesenteric vein is_a: XAO:0000115 ! vein relationship: develops_from XAO:0000358 ! venous endothelium [Term] id: XAO:0000377 name: capillary system of liver relationship: develops_from XAO:0000376 ! omphalomesenteric vein relationship: part_of XAO:0000133 ! liver [Term] id: XAO:0000378 name: musculoabdominal vein is_a: XAO:0000115 ! vein relationship: develops_from XAO:0000358 ! venous endothelium [Term] id: XAO:0000379 name: external jugular is_a: XAO:0000115 ! vein relationship: develops_from XAO:0000358 ! venous endothelium [Term] id: XAO:0000380 name: lateral postcardinal vein is_a: XAO:0000115 ! vein relationship: develops_from XAO:0000358 ! venous endothelium [Term] id: XAO:0000381 name: mesonephric sinus relationship: develops_from XAO:0000380 ! lateral postcardinal vein relationship: part_of XAO:0000140 ! urogenital system [Term] id: XAO:0000382 name: internal jugular is_a: XAO:0000115 ! vein relationship: develops_from XAO:0000358 ! venous endothelium [Term] id: XAO:0000383 name: anterior cardinal vein xref: ZFA:0000423 is_a: XAO:0000115 ! vein relationship: develops_from XAO:0000052 ! cardinal vein [Term] id: XAO:0000384 name: medial cardinal vein is_a: XAO:0000115 ! vein relationship: develops_from XAO:0000052 ! cardinal vein [Term] id: XAO:0000385 name: pronephric sinus relationship: develops_from XAO:0000373 ! duct of Cuvier relationship: develops_from XAO:0000383 ! anterior cardinal vein relationship: develops_from XAO:0000384 ! medial cardinal vein relationship: part_of XAO:0002000 ! pronephric kidney relationship: start_stage XAO:1000046 ! NF stage 31 [Term] id: XAO:0000386 name: interrenal vein is_a: XAO:0000115 ! vein relationship: develops_from XAO:0000384 ! medial cardinal vein [Term] id: XAO:0000387 name: hepatic vein xref: ZFA:0000670 is_a: XAO:0000115 ! vein relationship: develops_from XAO:0000358 ! venous endothelium [Term] id: XAO:0000388 name: posterior vena cava is_a: XAO:0000115 ! vein relationship: develops_from XAO:0000386 ! interrenal vein relationship: develops_from XAO:0000387 ! hepatic vein [Term] id: XAO:0000389 name: gastric vein is_a: XAO:0000115 ! vein relationship: develops_from XAO:0000358 ! venous endothelium [Term] id: XAO:0000390 name: caudal vein xref: ZFA:0000180 is_a: XAO:0000115 ! vein relationship: develops_from XAO:0000386 ! interrenal vein [Term] id: XAO:0000391 name: subinterstitial vein is_a: XAO:0000115 ! vein relationship: develops_from XAO:0000358 ! venous endothelium [Term] id: XAO:0000392 name: portal vein is_a: XAO:0000115 ! vein relationship: develops_from XAO:0000358 ! venous endothelium [Term] id: XAO:0000393 name: tail vein is_a: XAO:0000115 ! vein relationship: develops_from XAO:0000358 ! venous endothelium [Term] id: XAO:0000394 name: pulmonary vein is_a: XAO:0000115 ! vein relationship: develops_from XAO:0000358 ! venous endothelium [Term] id: XAO:0000395 name: medial abdominal vein is_a: XAO:0000115 ! vein relationship: develops_from XAO:0000358 ! venous endothelium [Term] id: XAO:0000396 name: head somite 1 def: "Transient occipital somite that exists from NF stages 17 to 26 only." [XB:curator "Xenbase"] synonym: "somite W" RELATED [PMID:2769206 "Chung et al."] is_a: XAO:0000313 ! head somite relationship: develops_from XAO:0000057 ! presomitic mesoderm relationship: end_stage XAO:1000042 ! NF stage 26 relationship: start_stage XAO:1000027 ! NF stage 17 [Term] id: XAO:0000397 name: sclerotome def: "Somitic compartment that is a precursor of the axial skeleton." [XB:curator "Xenbase"] synonym: "sclerotomes" RELATED PLURAL [] xref: ZFA:0001080 is_a: XAO:0003042 ! embryonic structure relationship: part_of XAO:0000058 ! somite [Term] id: XAO:0000399 name: tendon fibroblast is_a: XAO:0003017 ! fibroblast relationship: develops_from XAO:0000397 ! sclerotome [Term] id: XAO:0000401 name: sclerotomal cartilage is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000397 ! sclerotome [Term] id: XAO:0000403 name: head somite 2 def: "Transient occipital somite that exists from NF stages 18 to 29 only." [XB:curator "Xenbase"] synonym: "somite X" RELATED [PMID:2769206 "Chung et al."] is_a: XAO:0000313 ! head somite relationship: develops_from XAO:0000057 ! presomitic mesoderm relationship: end_stage XAO:1000045 ! NF stage 29 and 30 relationship: start_stage XAO:1000034 ! NF stage 18 [Term] id: XAO:0000404 name: head somite 3 def: "Transient occipital somite that exists from NF stages 18 to 29/30 only." [XB:curator "Xenbase"] synonym: "somite Y" RELATED [PMID:2769206 "Chung et al."] is_a: XAO:0000313 ! head somite relationship: develops_from XAO:0000057 ! presomitic mesoderm relationship: end_stage XAO:1000045 ! NF stage 29 and 30 relationship: start_stage XAO:1000034 ! NF stage 18 [Term] id: XAO:0000405 name: head somite 4 def: "Transient occipital somite that exists from NF stages 19 to late 30's." [XB:curator "Xenbase"] synonym: "somite Z" RELATED [PMID:2769206 "Chung et al."] is_a: XAO:0000313 ! head somite relationship: develops_from XAO:0000057 ! presomitic mesoderm relationship: start_stage XAO:1000034 ! NF stage 18 [Term] id: XAO:0000406 name: trunk somite 1 def: "Trunk somite that is initially the 5th somite, first forming around NF stage 19 and becoming more anteriorly positioned as the head somites degenerate. It is the most anterior somite by NF stage 45 and is adjacent to the otic vesicle." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 35)"] synonym: "fifth somite" RELATED [] is_a: XAO:0000314 ! trunk somite relationship: develops_from XAO:0000057 ! presomitic mesoderm relationship: start_stage XAO:1000035 ! NF stage 19 [Term] id: XAO:0000407 name: trunk somite 2 def: "Trunk somite that is initially the sixth somite." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 35)"] is_a: XAO:0000314 ! trunk somite relationship: develops_from XAO:0000057 ! presomitic mesoderm relationship: start_stage XAO:1000035 ! NF stage 19 [Term] id: XAO:0000408 name: trunk somite 3 is_a: XAO:0000314 ! trunk somite relationship: develops_from XAO:0000057 ! presomitic mesoderm relationship: start_stage XAO:1000036 ! NF stage 20 [Term] id: XAO:0000409 name: trunk somite 4 is_a: XAO:0000314 ! trunk somite relationship: develops_from XAO:0000057 ! presomitic mesoderm [Term] id: XAO:0000410 name: trunk somite 5 is_a: XAO:0000314 ! trunk somite relationship: develops_from XAO:0000057 ! presomitic mesoderm [Term] id: XAO:0000411 name: trunk somite 6 is_a: XAO:0000314 ! trunk somite relationship: develops_from XAO:0000057 ! presomitic mesoderm [Term] id: XAO:0000412 name: trunk somite 7 is_a: XAO:0000314 ! trunk somite relationship: develops_from XAO:0000057 ! presomitic mesoderm [Term] id: XAO:0000414 name: sclerotomal mesenchyme is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000397 ! sclerotome [Term] id: XAO:0000415 name: notochordal sheath relationship: develops_from XAO:0000414 ! sclerotomal mesenchyme relationship: part_of XAO:0000055 ! notochord [Term] id: XAO:0000416 name: trunk somite 8 is_a: XAO:0000314 ! trunk somite relationship: develops_from XAO:0000057 ! presomitic mesoderm [Term] id: XAO:0000417 name: trunk somite 9 is_a: XAO:0000314 ! trunk somite relationship: develops_from XAO:0000057 ! presomitic mesoderm [Term] id: XAO:0000418 name: trunk somite 10 is_a: XAO:0000314 ! trunk somite relationship: develops_from XAO:0000057 ! presomitic mesoderm [Term] id: XAO:0000419 name: trunk somite 11 is_a: XAO:0000314 ! trunk somite relationship: develops_from XAO:0000057 ! presomitic mesoderm [Term] id: XAO:0000420 name: trunk somite 12 is_a: XAO:0000314 ! trunk somite relationship: develops_from XAO:0000057 ! presomitic mesoderm [Term] id: XAO:0000421 name: trunk somite 13 is_a: XAO:0000314 ! trunk somite relationship: develops_from XAO:0000057 ! presomitic mesoderm [Term] id: XAO:0000422 name: trunk somite 14 is_a: XAO:0000314 ! trunk somite relationship: develops_from XAO:0000057 ! presomitic mesoderm [Term] id: XAO:0000423 name: trunk somite 15 is_a: XAO:0000314 ! trunk somite relationship: develops_from XAO:0000057 ! presomitic mesoderm relationship: start_stage XAO:1000043 ! NF stage 27 [Term] id: XAO:0000424 name: trunk somite 16 def: "Trunk somite that forms at NF stage 28, by which time head somite 1 has degenerated." [XB:curator "Xenbase"] is_a: XAO:0000314 ! trunk somite relationship: develops_from XAO:0000057 ! presomitic mesoderm relationship: start_stage XAO:1000044 ! NF stage 28 [Term] id: XAO:0000425 name: trunk somite 17 is_a: XAO:0000314 ! trunk somite relationship: develops_from XAO:0000057 ! presomitic mesoderm relationship: start_stage XAO:1000044 ! NF stage 28 [Term] id: XAO:0000426 name: cranial nerve I def: "Cranial nerve that supplies the nasal organ." [ISBN:0471209627 "Deuchar EM (pg. 29)"] synonym: "olfactory nerve" RELATED [] xref: ZFA:0000249 is_a: XAO:0003089 ! cranial nerve relationship: develops_from XAO:0000005 ! olfactory placode relationship: part_of XAO:0003196 ! olfactory system relationship: start_stage XAO:1000047 ! NF stage 32 [Term] id: XAO:0000427 name: gasserian ganglion synonym: "gasserian ganglia" RELATED PLURAL [] is_a: XAO:0000209 ! ganglion relationship: develops_from XAO:0000225 ! trigeminal placode [Term] id: XAO:0000428 name: trigeminal ganglion synonym: "trigeminal ganglia" RELATED PLURAL [] synonym: "trigeminus ganglion" RELATED [] xref: ZFA:0000295 is_a: XAO:0000209 ! ganglion relationship: develops_from XAO:0000225 ! trigeminal placode [Term] id: XAO:0000429 name: cephalic nerve is_a: XAO:0003089 ! cranial nerve [Term] id: XAO:0000430 name: Rathke's pouch is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000269 ! mouth primordium [Term] id: XAO:0000431 name: tooth synonym: "dentition" BROAD [] synonym: "teeth" RELATED PLURAL [] relationship: develops_from XAO:0000269 ! mouth primordium relationship: part_of XAO:0003075 ! cranium [Term] id: XAO:0000437 name: death namespace: xenopus_developmental_stage def: "The end of the animal's life." [XB:curator "Xenbase"] is_a: XAO:1000000 ! Xenopus developmental stage [Term] id: XAO:0000439 name: coelomic filter chamber synonym: "coelom" RELATED [] relationship: part_of XAO:0000311 ! lateral plate mesoderm relationship: start_stage XAO:1000044 ! NF stage 28 [Term] id: XAO:0000440 name: lateral line placode synonym: "lateral line placodes" RELATED PLURAL [] is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000305 ! cranial placode [Term] id: XAO:0000441 name: infraorbital lateral line primordium is_a: XAO:0003043 ! primordium relationship: develops_from XAO:0000440 ! lateral line placode relationship: start_stage XAO:1000048 ! NF stage 33 and 34 [Term] id: XAO:0000442 name: supraorbital lateral line xref: ZFA:0000443 relationship: develops_from XAO:0000440 ! lateral line placode relationship: part_of XAO:0000095 ! lateral line system relationship: start_stage XAO:1000048 ! NF stage 33 and 34 [Term] id: XAO:0000443 name: trunk lateral line relationship: develops_from XAO:0000440 ! lateral line placode relationship: part_of XAO:0000095 ! lateral line system relationship: start_stage XAO:1000048 ! NF stage 33 and 34 [Term] id: XAO:0000444 name: thyroid primordium xref: ZFA:0001081 is_a: XAO:0003043 ! primordium relationship: develops_from XAO:0000105 ! pharyngeal cavity relationship: end_stage XAO:1000061 ! NF stage 49 relationship: part_of XAO:0000158 ! endocrine system relationship: start_stage XAO:1000048 ! NF stage 33 and 34 [Term] id: XAO:0000445 name: taste bud xref: ZFA:0001074 relationship: develops_from XAO:0000105 ! pharyngeal cavity relationship: develops_from XAO:0000446 ! tongue relationship: part_of XAO:0003197 ! gustatory system relationship: start_stage XAO:1000063 ! NF stage 51 [Term] id: XAO:0000446 name: tongue relationship: develops_from XAO:0000097 ! mandibular arch relationship: part_of XAO:0003024 ! head relationship: start_stage XAO:1000052 ! NF stage 40 [Term] id: XAO:0000447 name: branchial arch 1 synonym: "first branchial arch" EXACT [] synonym: "third visceral arch" RELATED [] is_a: XAO:0000099 ! branchial arch relationship: develops_from XAO:0000251 ! visceral pouch 3 relationship: start_stage XAO:1000043 ! NF stage 27 [Term] id: XAO:0000448 name: gill primordium is_a: XAO:0003043 ! primordium relationship: develops_from XAO:0000447 ! branchial arch 1 relationship: develops_from XAO:0000449 ! branchial arch 2 relationship: end_stage XAO:1000051 ! NF stage 39 relationship: start_stage XAO:1000049 ! NF stage 35 and 36 [Term] id: XAO:0000449 name: branchial arch 2 synonym: "fourth visceral arch" RELATED [] synonym: "second branchial arch" EXACT [] is_a: XAO:0000099 ! branchial arch relationship: develops_from XAO:0000254 ! visceral pouch 4 relationship: start_stage XAO:1000047 ! NF stage 32 [Term] id: XAO:0000450 name: epithelial body relationship: develops_from XAO:0000247 ! visceral pouch 2 relationship: develops_from XAO:0000447 ! branchial arch 1 relationship: part_of XAO:0000158 ! endocrine system relationship: start_stage XAO:1000055 ! NF stage 43 [Term] id: XAO:0000451 name: branchial arch 3 synonym: "fifth visceral arch" RELATED [] synonym: "third branchial arch" EXACT [] is_a: XAO:0000099 ! branchial arch relationship: develops_from XAO:0000255 ! visceral pouch 5 relationship: start_stage XAO:1000049 ! NF stage 35 and 36 [Term] id: XAO:0000452 name: ultimobranchial body xref: ZFA:0001448 relationship: develops_from XAO:0000453 ! branchial arch 4 relationship: part_of XAO:0000158 ! endocrine system relationship: start_stage XAO:1000052 ! NF stage 40 [Term] id: XAO:0000453 name: branchial arch 4 synonym: "fourth branchial arch" EXACT [] synonym: "sixth visceral arch" RELATED [] is_a: XAO:0000099 ! branchial arch relationship: develops_from XAO:0000265 ! visceral pouch 6 [Term] id: XAO:0000454 name: liver parenchyme relationship: develops_from XAO:0000101 ! liver diverticulum relationship: part_of XAO:0000133 ! liver [Term] id: XAO:0000455 name: biliary tree relationship: develops_from XAO:0000101 ! liver diverticulum relationship: part_of XAO:0000132 ! liver and biliary system [Term] id: XAO:0000457 name: pyloric sphincter relationship: develops_from XAO:0000128 ! stomach relationship: part_of XAO:0000125 ! alimentary system [Term] id: XAO:0000458 name: occipital lateral line xref: ZFA:0000400 relationship: develops_from XAO:0000440 ! lateral line placode relationship: part_of XAO:0000095 ! lateral line system relationship: start_stage XAO:1000050 ! NF stage 37 and 38 [Term] id: XAO:0000459 name: infraorbital lateral line xref: ZFA:0000524 relationship: develops_from XAO:0000441 ! infraorbital lateral line primordium relationship: part_of XAO:0000095 ! lateral line system [Term] id: XAO:0000460 name: hyomandibular lateral line relationship: develops_from XAO:0000441 ! infraorbital lateral line primordium relationship: part_of XAO:0000095 ! lateral line system relationship: start_stage XAO:1000055 ! NF stage 43 [Term] id: XAO:0000461 name: trunk placode is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000320 ! sensorial layer [Term] id: XAO:0000462 name: dorsal lateral line xref: ZFA:0005112 relationship: develops_from XAO:0000461 ! trunk placode relationship: part_of XAO:0000095 ! lateral line system [Term] id: XAO:0000463 name: middle lateral line xref: ZFA:0000344 relationship: develops_from XAO:0000461 ! trunk placode relationship: part_of XAO:0000095 ! lateral line system [Term] id: XAO:0000464 name: ventral lateral line relationship: develops_from XAO:0000461 ! trunk placode relationship: part_of XAO:0000095 ! lateral line system relationship: start_stage XAO:1000049 ! NF stage 35 and 36 [Term] id: XAO:0000465 name: caudal lateral line relationship: develops_from XAO:0000464 ! ventral lateral line relationship: part_of XAO:0000095 ! lateral line system relationship: start_stage XAO:1000056 ! NF stage 44 [Term] id: XAO:0000467 name: dorsal pancreatic bud is_a: XAO:0003043 ! primordium relationship: develops_from XAO:0000103 ! midgut relationship: end_stage XAO:1000052 ! NF stage 40 relationship: start_stage XAO:1000049 ! NF stage 35 and 36 [Term] id: XAO:0000469 name: dorsal fin xref: ZFA:0001173 is_a: XAO:0000002 ! fin relationship: develops_from XAO:0000319 ! trunk neural crest relationship: start_stage XAO:1000043 ! NF stage 27 [Term] id: XAO:0000470 name: unicellular gland def: "Any of the large number of glands of the larval skin, particularly common in the fins and adjacent skin of the trunk; also formed in the former frontal gland area on the upper jaw." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 44)"] is_a: XAO:0003028 ! surface structure relationship: develops_from XAO:0000320 ! sensorial layer relationship: start_stage XAO:1000062 ! NF stage 50 [Term] id: XAO:0000471 name: xanthophore xref: CL:0000430 is_a: XAO:0003014 ! pigment cell relationship: start_stage XAO:1000058 ! NF stage 46 [Term] id: XAO:0000472 name: iridophore synonym: "guanophore" RELATED [] xref: CL:0000431 is_a: XAO:0003014 ! pigment cell relationship: start_stage XAO:1000071 ! NF stage 59 [Term] id: XAO:0000474 name: choroid fissure def: "A break in the continuity of the optic cup where the two sides of the cup meet." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 77)"] xref: ZFA:0001075 is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000228 ! eye vesicle relationship: end_stage XAO:1000058 ! NF stage 46 relationship: start_stage XAO:1000047 ! NF stage 32 [Term] id: XAO:0000475 name: optic stalk xref: ZFA:0000137 relationship: develops_from XAO:0000228 ! eye vesicle relationship: part_of XAO:0000013 ! diencephalon relationship: start_stage XAO:1000046 ! NF stage 31 [Term] id: XAO:0001001 name: cranial neural crest def: "Neural crest that is part of the head." [ZFA:0001194] synonym: "head crest" RELATED [] xref: ZFA:0001194 relationship: end_stage XAO:1000046 ! NF stage 31 relationship: part_of XAO:0000048 ! neural crest relationship: start_stage XAO:1000025 ! NF stage 15 [Term] id: XAO:0001002 name: lung primordium def: "A pair of lateral diverticula just over the liver rudiment representing the primordia of the lungs, formed by the floor of the foregut just anterior to the liver diverticulum." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 42)"] synonym: "lateral diverticula" RELATED [] is_a: XAO:0003043 ! primordium relationship: develops_from XAO:0000232 ! foregut relationship: part_of XAO:0000117 ! respiratory system relationship: start_stage XAO:1000046 ! NF stage 31 [Term] id: XAO:0001010 name: circulatory system def: "Anatomical system that has as its parts the blood and lymph vessels." [XB:curator "Xenbase"] synonym: "vasculature" RELATED [] xref: ZFA:0001079 is_a: XAO:0003002 ! anatomical system relationship: end_stage XAO:0000437 ! death [Term] id: XAO:0001011 name: blood vessel def: "Any of the vessels through which blood circulates in the body." [BTO:0001102] synonym: "vasculature" RELATED [] relationship: part_of XAO:0000100 ! cardiovascular system relationship: part_of XAO:0001010 ! circulatory system relationship: start_stage XAO:1000046 ! NF stage 31 [Term] id: XAO:0001012 name: Stirnorgan synonym: "frontal organ" RELATED [] relationship: develops_from XAO:0000160 ! pineal gland relationship: part_of XAO:0003198 ! visual system relationship: start_stage XAO:1000054 ! NF stage 42 [Term] id: XAO:0001013 name: facial muscle is_a: XAO:0000172 ! muscle relationship: start_stage XAO:1000052 ! NF stage 40 [Term] id: XAO:0001014 name: melanophore def: "A pigment cell that contains melanin, a brownish-black pigment." [NLM:melanophore "MedlinePlus Medical Dictionary"] synonym: "melanocyte" RELATED [] xref: CL:0000148 is_a: XAO:0003014 ! pigment cell relationship: start_stage XAO:1000048 ! NF stage 33 and 34 [Term] id: XAO:0001015 name: rectal diverticulum synonym: "rectal diverticula" RELATED PLURAL [] relationship: develops_from XAO:0000244 ! cloaca relationship: part_of XAO:0002000 ! pronephric kidney relationship: start_stage XAO:1000047 ! NF stage 32 [Term] id: XAO:0001016 name: abdominal myoblast is_a: XAO:0003015 ! myoblast relationship: start_stage XAO:1000046 ! NF stage 31 [Term] id: XAO:0001017 name: portion of connective tissue def: "Portion of tissue that consists of mesodermally derived cells and intercellular matrix comprised of protein fibers and carbohydrates, which supports, ensheathes and binds together other tissues." [ZFA:0001632] xref: ZFA:0001632 is_a: XAO:0003040 ! portion of tissue [Term] id: XAO:0001018 name: anterior lymph sac synonym: "rostral lymph sac" RELATED [] relationship: develops_from XAO:0000358 ! venous endothelium relationship: part_of XAO:0003199 ! lymphatic system relationship: start_stage XAO:1000047 ! NF stage 32 [Term] id: XAO:0001019 name: proctodeum def: "Inward fold on the surface of the embryonic ectoderm that develops into part of the anal passage." [ZFA:0000066] synonym: "anus" RELATED [] synonym: "proctodaeum" EXACT [] xref: ZFA:0000066 is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000001 ! ectoderm relationship: part_of XAO:0000125 ! alimentary system relationship: start_stage XAO:1000037 ! NF stage 21 [Term] id: XAO:0001020 name: elastica externa def: "Notochordal sheath or membrane. Its first indication is at NF stage 24, and it is a distinct membrane by NF stage 28." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 36)"] synonym: "notochordal sheath" RELATED [] is_a: XAO:0003042 ! embryonic structure relationship: develops_from XAO:0000055 ! notochord relationship: end_stage XAO:1000074 ! NF stage 62 relationship: start_stage XAO:1000040 ! NF stage 24 [Term] id: XAO:0001021 name: notochordal epithelium is_a: XAO:0003045 ! epithelium relationship: develops_from XAO:0000055 ! notochord relationship: start_stage XAO:1000046 ! NF stage 31 [Term] id: XAO:0001101 name: first pancreatic bud is_a: XAO:0003043 ! primordium relationship: develops_from XAO:0000232 ! foregut relationship: end_stage XAO:1000051 ! NF stage 39 relationship: start_stage XAO:1000050 ! NF stage 37 and 38 [Term] id: XAO:0001102 name: second pancreatic bud is_a: XAO:0003043 ! primordium relationship: develops_from XAO:0000232 ! foregut [Term] id: XAO:0001103 name: ventral pancreatic bud is_a: XAO:0003043 ! primordium relationship: develops_from XAO:0001101 ! first pancreatic bud relationship: start_stage XAO:1000051 ! NF stage 39 [Term] id: XAO:0002000 name: pronephric kidney def: "Organ that serves as a transient kidney, providing osmoregulation during early developmental stages and then degenerating during metamorphosis." [XB:curator "Xenbase"] subset: frequent_anatomy_items synonym: "pronephros" RELATED [] xref: ZFA:0000151 relationship: develops_from XAO:0000264 ! pronephric mesenchyme relationship: part_of XAO:0000143 ! urinary system relationship: start_stage XAO:1000045 ! NF stage 29 and 30 [Term] id: XAO:0003000 name: anatomical structure def: "Material anatomical entity that has inherent 3D shape and is generated by coordinated expression of the organism's own genome." [CARO:0000003] xref: CARO:0000003 is_a: XAO:0000000 ! Xenopus anatomical entity relationship: end_stage XAO:0000437 ! death relationship: start_stage XAO:1000001 ! NF stage 1 [Term] id: XAO:0003001 name: anatomical group def: "Anatomical structure consisting of at least two non-overlapping organs, multi-tissue aggregates or portion of tissues or cells of different types that does not constitute an organism, organ, multi-tissue aggregate, or portion of tissue." [CARO:0000054] xref: CARO:0000054 is_a: XAO:0003000 ! anatomical structure relationship: end_stage XAO:0000437 ! death relationship: start_stage XAO:1000001 ! NF stage 1 [Term] id: XAO:0003002 name: anatomical system def: "Anatomical group that has as its parts distinct anatomical structures interconnected by anatomical structures at a lower level of granularity." [CARO:0000011] xref: CARO:0000011 is_a: XAO:0003001 ! anatomical group relationship: end_stage XAO:0000437 ! death relationship: part_of XAO:0003004 ! whole organism relationship: start_stage XAO:1000001 ! NF stage 1 [Term] id: XAO:0003003 name: unspecified comment: Annotation of data with this anatomy term indicates that a structure or tissue was not specified by the investigator. is_a: XAO:0000000 ! Xenopus anatomical entity [Term] id: XAO:0003004 name: whole organism def: "Anatomical structure that is an individual member of Xenopus laevis." [CARO:0000012] subset: organism_views subset: sectional_anatomy_items xref: CARO:0000012 is_a: XAO:0003000 ! anatomical structure relationship: end_stage XAO:0000437 ! death relationship: start_stage XAO:1000001 ! NF stage 1 [Term] id: XAO:0003005 name: female organism def: "Gonochoristic organism that can produce female gametes." [CARO:0000028] xref: CARO:0000028 is_a: XAO:0003004 ! whole organism relationship: end_stage XAO:0000437 ! death relationship: start_stage XAO:1000001 ! NF stage 1 [Term] id: XAO:0003006 name: male organism def: "Gonochoristic organism that can produce male gametes." [CARO:0000027] xref: CARO:0000027 is_a: XAO:0003004 ! whole organism relationship: end_stage XAO:0000437 ! death relationship: start_stage XAO:1000001 ! NF stage 1 [Term] id: XAO:0003007 name: anatomical entity in vitro namespace: xenopus_anatomy_in_vitro is_a: XAO:0000000 ! Xenopus anatomical entity [Term] id: XAO:0003008 name: activin-induced ectoderm namespace: xenopus_anatomy_in_vitro is_a: XAO:0003007 ! anatomical entity in vitro [Term] id: XAO:0003009 name: disaggregated/reaggregated ectoderm treated with activin namespace: xenopus_anatomy_in_vitro is_a: XAO:0003007 ! anatomical entity in vitro [Term] id: XAO:0003010 name: aorta is_a: XAO:0000114 ! artery [Term] id: XAO:0003011 name: primary germ layer def: "A layer of cells produced during the process of gastrulation during the early development of the embryo, which is distinct from other such layers of cells, as an early step of cell differentiation. The types of germ layers are the endoderm, ectoderm, and mesoderm." [BTO:0000556] synonym: "embryonic germ layer" RELATED [] synonym: "germ layer" RELATED [] xref: ZFA:0001122 is_a: XAO:0003042 ! embryonic structure relationship: part_of XAO:0000113 ! embryo [Term] id: XAO:0003012 name: cell def: "Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." [GO:0005623] xref: CARO:0000013 is_a: XAO:0003000 ! anatomical structure relationship: end_stage XAO:0000437 ! death relationship: part_of XAO:0003004 ! whole organism relationship: start_stage XAO:1000001 ! NF stage 1 [Term] id: XAO:0003013 name: organism subdivision def: "Anatomical structure that is a primary subdivision of the whole organism." [CARO:0000032] synonym: "body part" RELATED [] xref: CARO:0000032 is_a: XAO:0003000 ! anatomical structure relationship: end_stage XAO:0000437 ! death relationship: part_of XAO:0003004 ! whole organism [Term] id: XAO:0003014 name: pigment cell def: "Cell type that contains a deposition of coloring matter, the first of which differentiate during late tailbud stage, and that by NF stage 56 has produced a fully differentiated larval pigmentation pattern." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 44-51)", NLM:pigment+cell "MedlinePlus Medical Dictionary"] synonym: "chromatophore" RELATED [] xref: CL:0000147 is_a: XAO:0003012 ! cell relationship: develops_from XAO:0000319 ! trunk neural crest relationship: part_of XAO:0000023 ! skin relationship: start_stage XAO:1000047 ! NF stage 32 [Term] id: XAO:0003015 name: myoblast def: "Embryonic (precursor) cell of the myogenic lineage that develops from the mesoderm." [CL:0000056] xref: CL:0000056 is_a: XAO:0003012 ! cell [Term] id: XAO:0003016 name: blastomere def: "Undifferentiated cell that is produced by early cleavages of the fertilized egg (zygote)." [CL:0000353] synonym: "blastoderm cell" EXACT [CL:0000353] xref: CL:0000353 is_a: XAO:0003012 ! cell relationship: end_stage XAO:1000019 ! NF stage 9 relationship: start_stage XAO:1000011 ! NF stage 2 (2-cell) [Term] id: XAO:0003017 name: fibroblast def: "A connective tissue cell that secretes an extracellular matrix rich in collagen and other macromolecules." [CL:0000057] xref: CL:0000057 is_a: XAO:0003012 ! cell [Term] id: XAO:0003018 name: primary spermatogonium synonym: "primary spermatogonia" RELATED PLURAL [] is_a: XAO:0000111 ! germ cell relationship: develops_from XAO:0003149 ! primordial germ cell relationship: part_of XAO:0000157 ! testis [Term] id: XAO:0003019 name: spermatocyte def: "The developing male gamete." [XB:curator "Xenbase"] xref: CL:0000017 is_a: XAO:0000111 ! germ cell relationship: develops_from XAO:0003020 ! secondary spermatogonium [Term] id: XAO:0003020 name: secondary spermatogonium synonym: "secondary spermatogonia" RELATED PLURAL [] is_a: XAO:0000111 ! germ cell relationship: develops_from XAO:0003018 ! primary spermatogonium [Term] id: XAO:0003021 name: spinal cord neuron is_obsolete: true [Term] id: XAO:0003022 name: Rohon-Beard neuron def: "Type of neuron that is a primary mechanosensory cell, with peripheral neurites innervating the skin with free nerve endings. It first appears in trunk levels at NF stage 33/34, and at NF stage 35/36 has somas that are the largest in the spinal cord. It forms a nearly continuous double row of cells along the cord's medial dorsal surface and contributes ascending and descending axons to the dorsal tract. It appears well back in the tail by NF stage 39, begins to decline at NF stage 50 and is few in number, with pycnotic nuclei, at NF stage 55." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 67-69)", PMID:17506218 "Roberts A and Clarke JD"] synonym: "Rohon Beard cell" RELATED [] xref: CL:0000247 is_a: XAO:0003023 ! neuron relationship: end_stage XAO:1000067 ! NF stage 55 relationship: part_of XAO:0000020 ! spinal cord relationship: start_stage XAO:1000048 ! NF stage 33 and 34 [Term] id: XAO:0003023 name: neuron def: "Cell that is the basic unit of nervous tissue, each consisting of a body, an axon, and dendrites, and the purpose of which is to receive, conduct, and transmit impulses in the nervous system." [CL:0000540] synonym: "nerve cell" RELATED [] xref: CL:0000540 is_a: XAO:0003012 ! cell [Term] id: XAO:0003024 name: head def: "Organism subdivision that is the part of the body consisting of the cranial and pharyngeal regions." [ZFA:0001114] subset: frequent_anatomy_items subset: organism_views xref: ZFA:0001114 is_a: XAO:0003013 ! organism subdivision relationship: end_stage XAO:0000437 ! death [Term] id: XAO:0003025 name: trunk def: "Organism subdivision that is the part of the body posterior to the head and anterior to the tail." [ZFA:0001115] subset: organism_views xref: ZFA:0001115 is_a: XAO:0003013 ! organism subdivision relationship: end_stage XAO:0000437 ! death [Term] id: XAO:0003026 name: tail def: "Organism subdivision that is the terminal, flexible posterior appendage of the larva. It is resorbed during metamorphosis beginning with degeneration of the notochord's distal tip at NF stage 61, followed by degeneration gradually extending to its more proximal regions and reaching its proximal end by NF stage 62. By NF stage 66 it exists only as a small dorsal swelling." [ISBN:0471209627 "Deuchar EM (pg. 121)", OMD:tail "CancerWeb Online Medical Dictionary"] subset: organism_views is_a: XAO:0003013 ! organism subdivision relationship: end_stage XAO:1000078 ! NF stage 66 [Term] id: XAO:0003027 name: limb def: "Organism subdivision that has as its parts the jointed appendages used for locomotion and manipulation." [XB:curator "Xenbase"] is_a: XAO:0003013 ! organism subdivision relationship: end_stage XAO:0000437 ! death [Term] id: XAO:0003028 name: surface structure def: "Organism subdivision that is the collection of anatomical structures on the body surface." [ZFA:0000292] xref: ZFA:0000292 is_a: XAO:0003013 ! organism subdivision relationship: end_stage XAO:0000437 ! death [Term] id: XAO:0003029 name: mouth def: "The opening of the head through which food passes into the body." [NLM:mouth "MedlinePlus Medical Dictionary"] xref: ZFA:0000547 relationship: part_of XAO:0003024 ! head [Term] id: XAO:0003030 name: forelimb def: "One of the pair of limbs that are situated anteriorly, develop in sacs that separate them from the gill chamber, are well-defined buds by NF stage 48, are innervated by NF stage 51, and are ossified by NF stage 59." [BTO:0001729, ISBN:0471209627 "Deuchar EM (pg. 123)"] xref: AAO:0000202 is_a: XAO:0003027 ! limb relationship: develops_from XAO:0003065 ! forelimb bud [Term] id: XAO:0003031 name: hind limb def: "One of the pair of limbs that are situated posteriorly, are evident as buds laterally by NF stage 47, and are innervated by NF stage 51." [ISBN:0471209627 "Deuchar EM (pg. 122)"] synonym: "hindlimb" EXACT [] xref: AAO:0000217 is_a: XAO:0003027 ! limb relationship: develops_from XAO:0003066 ! hind limb bud [Term] id: XAO:0003032 name: digit def: "One of several most distal parts of a limb." [XB:curator "Xenbase"] is_a: XAO:0003160 ! anatomical cluster [Term] id: XAO:0003033 name: nostril def: "Surface structure that provides one of the small external openings of the head that give passage to air for breathing." [OMD:nostril "CancerWeb Online Medical Dictionary"] is_a: XAO:0003028 ! surface structure relationship: part_of XAO:0003024 ! head [Term] id: XAO:0003034 name: viscus def: "An internal organ of the body; especially: one (as the heart, liver, or intestine) located in the great cavity of the trunk proper." [BTO:0001491] synonym: "viscera" RELATED PLURAL [] xref: BTO:0001491 relationship: part_of XAO:0003025 ! trunk [Term] id: XAO:0003035 name: hind digit def: "A digit that is one of several most distal parts of a hind limb." [XB:curator "Xenbase"] xref: AAO:0000888 is_a: XAO:0003032 ! digit relationship: part_of XAO:0003031 ! hind limb relationship: part_of XAO:0003062 ! hind limb skeleton [Term] id: XAO:0003036 name: fore digit def: "A digit that is one of several most distal parts of a forelimb." [XB:curator "Xenbase"] xref: AAO:0000857 is_a: XAO:0003032 ! digit relationship: part_of XAO:0003030 ! forelimb relationship: part_of XAO:0003061 ! forelimb skeleton [Term] id: XAO:0003037 name: multi-tissue structure def: "Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types." [CARO:0000055] xref: CARO:0000055 is_a: XAO:0003000 ! anatomical structure relationship: end_stage XAO:0000437 ! death [Term] id: XAO:0003038 name: simple organ def: "Multi-tissue structure that is not part of a compound organ." [CARO:0000021] xref: CARO:0000021 is_a: XAO:0003037 ! multi-tissue structure relationship: end_stage XAO:0000437 ! death [Term] id: XAO:0003039 name: compound organ component def: "Multi-tissue structure that is part of a compound organ." [CARO:0000019] xref: CARO:0000019 is_a: XAO:0003037 ! multi-tissue structure relationship: end_stage XAO:0000437 ! death [Term] id: XAO:0003040 name: portion of tissue def: "Anatomical structure that consists of similar cells and intercellular matrix, aggregated according to genetically determined spatial relationships." [CARO:0000043] xref: CARO:0000043 is_a: XAO:0003000 ! anatomical structure relationship: end_stage XAO:0000437 ! death relationship: part_of XAO:0003004 ! whole organism [Term] id: XAO:0003041 name: compound organ def: "Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types." [CARO:0000024] xref: CARO:0000024 is_a: XAO:0003000 ! anatomical structure relationship: end_stage XAO:0000437 ! death relationship: start_stage XAO:1000037 ! NF stage 21 [Term] id: XAO:0003042 name: embryonic structure def: "An anatomical structure that exists only before the organism is fully formed." [BTO:0000174] xref: ZFA:0001105 relationship: part_of XAO:0003004 ! whole organism relationship: start_stage XAO:1000001 ! NF stage 1 [Term] id: XAO:0003043 name: primordium def: "An embryonic structure that is the rudiment or commencement of a part or organ." [BTO:0001886] is_a: XAO:0003042 ! embryonic structure [Term] id: XAO:0003044 name: endomesoderm def: "Primary germ layer that can give rise to both mesoderm and endoderm." [XB:curator "Xenbase"] synonym: "mesendoderm" RELATED [] is_a: XAO:0003011 ! primary germ layer [Term] id: XAO:0003045 name: epithelium def: "Portion of tissue that consists of one or more layers of epithelial cells connected to each other by cell junctions and that is underlain by a basal lamina." [CARO:0000066] xref: CARO:0000066 is_a: XAO:0003040 ! portion of tissue [Term] id: XAO:0003046 name: mesenchyme def: "Portion of tissue consisting of loosely organized undifferentiated mesodermal cells that give rise to such structures as connective tissues, blood, lymphatics, bone, and cartilage." [BTO:0001393] xref: ZFA:0000393 is_a: XAO:0003040 ! portion of tissue [Term] id: XAO:0003047 name: nerve def: "Portion of tissue that consists of a fasciculated group of axons." [ZFA:0007009] xref: ZFA:0007009 is_a: XAO:0003040 ! portion of tissue [Term] id: XAO:0003048 name: egg def: "A mature female germ cell that is capable of initiating formation of a new individual by fusion with a male gamete." [NLM:gamete "MedlinePlus Medical Dictionary"] synonym: "ovum" RELATED [] synonym: "unfertilized egg" RELATED [] xref: CL:0000025 is_a: XAO:0003150 ! gamete relationship: develops_from XAO:0000256 ! oocyte relationship: end_stage XAO:1000009 ! adult [Term] id: XAO:0003049 name: adipose tissue def: "Connective tissue in which fat is stored." [NLM:adipose+tissue "MedlinePlus Medical Dictionary"] is_a: XAO:0003040 ! portion of tissue [Term] id: XAO:0003050 name: fat body is_a: XAO:0003049 ! adipose tissue [Term] id: XAO:0003051 name: dorsal lateral plate region def: "Region located near the pronephros and pronephric ducts that is a site of hematopoiesis in the embryo." [PMID:9618755 "Huber TL and Zon LI"] synonym: "AGM region" RELATED [] synonym: "aorta-gonads-mesonephros region" RELATED [] synonym: "DLP" EXACT [] relationship: part_of XAO:0000122 ! hematological system relationship: part_of XAO:0000311 ! lateral plate mesoderm relationship: start_stage XAO:1000023 ! NF stage 13 [Term] id: XAO:0003052 name: oviduct xref: ZFA:0000560 relationship: part_of XAO:0000156 ! female genitalia relationship: start_stage XAO:1000076 ! NF stage 64 [Term] id: XAO:0003053 name: Keller explant namespace: xenopus_anatomy_in_vitro def: "A rectangle of dorsal mesendoderm and ectoderm from an early-gastrula-stage Xenopus laevis embryo. It is approximately 60 deg to 90 deg wide, extending from the bottle cells to the animal pole." [ISBN:9780879695040 "CSH Protocols (2007)"] is_a: XAO:0003007 ! anatomical entity in vitro [Term] id: XAO:0003054 name: stem cell def: "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [CL:0000034] xref: CL:0000034 is_a: XAO:0003012 ! cell [Term] id: XAO:0003055 name: hematopoietic stem cell synonym: "HSC" EXACT [] xref: CL:0000037 is_a: XAO:0003054 ! stem cell relationship: part_of XAO:0000067 ! blood island relationship: part_of XAO:0003051 ! dorsal lateral plate region [Term] id: XAO:0003056 name: anterior subset: anatomical_site_slim subset: sectional_anatomy_items is_a: XAO:0003185 ! anatomical direction [Term] id: XAO:0003057 name: posterior subset: anatomical_site_slim subset: sectional_anatomy_items is_a: XAO:0003185 ! anatomical direction [Term] id: XAO:0003058 name: larval structure is_obsolete: true [Term] id: XAO:0003059 name: chondrocranium def: "Structure consisting of a cartilaginous skull that begins to form during early tadpole stage." [ISBN:0471209627 "Deuchar EM (pg. 118)"] synonym: "cartilaginous skull" RELATED [] is_a: XAO:0003075 ! cranium [Term] id: XAO:0003060 name: skeletal system def: "Anatomical system that provides physical support to the organism." [AAO:0000566] xref: AAO:0000566 relationship: part_of XAO:0000168 ! musculoskeletal system [Term] id: XAO:0003061 name: forelimb skeleton def: "Skeletal structure of the paired, anterior appendages." [AAO:0000202] xref: AAO:0000202 relationship: part_of XAO:0003166 ! appendicular skeleton [Term] id: XAO:0003062 name: hind limb skeleton def: "Skeletal structure of the paired, posterior appendages." [AAO:0000217] xref: AAO:0000217 relationship: part_of XAO:0003166 ! appendicular skeleton [Term] id: XAO:0003063 name: pectoral girdle def: "Arched skeletal structure that supports the forelimbs, the rudiments of which can be distinguished in mesenchyme at NF stage 51, and is complete by NF stage 60." [ISBN:0471209627 "Deuchar EM (pg. 123)", NLM:pectoral+girdle "MedlinePlus Medical Dictionary"] synonym: "shoulder girdle" RELATED [] xref: AAO:0000422 is_a: XAO:0003160 ! anatomical cluster relationship: part_of XAO:0003166 ! appendicular skeleton relationship: start_stage XAO:1000063 ! NF stage 51 [Term] id: XAO:0003064 name: pelvic girdle def: "Arched skeletal structure that supports the hind limbs, begins to develop at NF stage 50, and is ossified by NF stage 66." [ISBN:0471209627 "Deuchar EM (pg. 122-3)", NLM:pelvic+girdle "MedlinePlus Medical Dictionary"] xref: AAO:0000426 is_a: XAO:0003160 ! anatomical cluster relationship: part_of XAO:0003166 ! appendicular skeleton relationship: start_stage XAO:1000062 ! NF stage 50 [Term] id: XAO:0003065 name: forelimb bud is_a: XAO:0003161 ! limb bud relationship: start_stage XAO:1000060 ! NF stage 48 [Term] id: XAO:0003066 name: hind limb bud is_a: XAO:0003161 ! limb bud relationship: start_stage XAO:1000058 ! NF stage 46 [Term] id: XAO:0003067 name: fore epipodium is_obsolete: true [Term] id: XAO:0003068 name: fore mesopodium is_obsolete: true [Term] id: XAO:0003069 name: hind propodium is_obsolete: true [Term] id: XAO:0003070 name: hind metapodium is_obsolete: true [Term] id: XAO:0003071 name: fore propodium is_obsolete: true [Term] id: XAO:0003072 name: hind epipodium is_obsolete: true [Term] id: XAO:0003073 name: postcranial axial skeleton def: "Skeletal structure that has as its parts the vertebral column, located in the dorsal part of the trunk, and formed by a series of vertebrae. It provides suspension for the appendicular skeleton and protection for the spinal nerve cord." [AAO:0000034] synonym: "axial skeleton" RELATED [] xref: AAO:0000034 is_a: XAO:0003060 ! skeletal system relationship: develops_from XAO:0000401 ! sclerotomal cartilage [Term] id: XAO:0003074 name: vertebral column xref: ZFA:0001559 relationship: part_of XAO:0003073 ! postcranial axial skeleton [Term] id: XAO:0003075 name: cranium synonym: "cranial skeleton" RELATED [] xref: AAO:0000109 is_a: XAO:0003060 ! skeletal system relationship: part_of XAO:0003024 ! head [Term] id: XAO:0003076 name: cervical vertebra relationship: part_of XAO:0003074 ! vertebral column [Term] id: XAO:0003077 name: presacral vertebra relationship: part_of XAO:0003074 ! vertebral column [Term] id: XAO:0003078 name: sacral vertebra relationship: part_of XAO:0003074 ! vertebral column [Term] id: XAO:0003079 name: caudal vertebra xref: ZFA:0000326 relationship: part_of XAO:0003074 ! vertebral column [Term] id: XAO:0003080 name: urostyle xref: ZFA:0000158 relationship: part_of XAO:0003073 ! postcranial axial skeleton [Term] id: XAO:0003081 name: larynx relationship: part_of XAO:0000117 ! respiratory system [Term] id: XAO:0003082 name: sucker is_obsolete: true consider: XAO:0000033 [Term] id: XAO:0003083 name: braincase and otic capsule skeleton xref: AAO:0000052 relationship: part_of XAO:0003075 ! cranium [Term] id: XAO:0003084 name: lower jaw xref: AAO:0000272 relationship: part_of XAO:0003075 ! cranium [Term] id: XAO:0003085 name: Meckel's cartilage def: "Paired cartilaginous component of the lower jaw that fuses together through a median inferior labial cartilage, resulting in a single curved bar of cartilage by metamorphic climax. During metamorphosis it is surrounded by the developing dentale and goniale." [PMID:3693112 "Thomson DA"] xref: AAO:0000289 relationship: part_of XAO:0003084 ! lower jaw [Term] id: XAO:0003086 name: suspensorium xref: AAO:0000596 is_a: XAO:0003160 ! anatomical cluster relationship: part_of XAO:0003176 ! splanchnocranium [Term] id: XAO:0003087 name: upper jaw xref: AAO:0000620 relationship: part_of XAO:0003075 ! cranium [Term] id: XAO:0003088 name: seminiferous tubule relationship: part_of XAO:0000157 ! testis relationship: start_stage XAO:1000067 ! NF stage 55 [Term] id: XAO:0003089 name: cranial nerve def: "Any of the major paired nerves of the head region." [XB:curator "Xenbase"] synonym: "cranial nerves" RELATED PLURAL [] xref: ZFA:0000641 is_a: XAO:0003047 ! nerve relationship: part_of XAO:0000178 ! peripheral nervous system [Term] id: XAO:0003090 name: cranial nerve III def: "Cranial nerve that runs to the eye muscles." [ISBN:0471209627 "Deuchar EM (pg. 29)"] synonym: "oculomotor nerve" RELATED [] xref: ZFA:0000405 is_a: XAO:0000429 ! cephalic nerve [Term] id: XAO:0003091 name: cranial nerve IV def: "Cranial nerve, also known as the pathetic nerve, that runs to the eye muscles." [ISBN:0471209627 "Deuchar EM (pg. 29)"] synonym: "pathetic nerve" RELATED [] synonym: "trochlear nerve" RELATED [] xref: ZFA:0000600 is_a: XAO:0000429 ! cephalic nerve [Term] id: XAO:0003092 name: cranial nerve V def: "Cranial nerve that branches into the ophthalmic (supplying the skin of the nose and upper jaw) and the mandibular (supplying the lower jaw)." [ISBN:0471209627 "Deuchar EM (pg. 28)"] synonym: "trigeminal nerve" RELATED [] xref: ZFA:0000697 is_a: XAO:0000429 ! cephalic nerve [Term] id: XAO:0003093 name: cranial nerve VI def: "Cranial nerve, also known as the abducent nerve, that runs to the eye muscles." [ISBN:0471209627 "Deuchar EM (pg. 29)"] synonym: "abducens nerve" RELATED [] synonym: "abducent nerve" RELATED [] xref: ZFA:0000310 is_a: XAO:0000429 ! cephalic nerve [Term] id: XAO:0003094 name: cranial nerve VII def: "Cranial nerve that branches into the supraorbital (supplying the skin of the eye region and the lateral line organs here), the palatine (to the roof of the buccal cavity), and the hyomandibular (dividing into the jugular and mental branches)." [ISBN:0471209627 "Deuchar EM (pg. 28)"] synonym: "facial nerve" RELATED [] xref: ZFA:0000664 is_a: XAO:0000429 ! cephalic nerve relationship: part_of XAO:0003197 ! gustatory system [Term] id: XAO:0003095 name: cranial nerve VIII def: "Cranial nerve that runs to the ear." [ISBN:0471209627 "Deuchar EM (pg. 29)"] synonym: "auditory nerve" RELATED [] xref: ZFA:0000247 is_a: XAO:0000429 ! cephalic nerve relationship: part_of XAO:0003195 ! vestibuloauditory system [Term] id: XAO:0003096 name: cranial nerve IX def: "Cranial nerve that branches into the ramus communicans (to the skin), the pretrematic (to the walls of the pharynx and mouth, viscero-sensory fibers), and the larval post-trematic branch (lost in the adult)." [ISBN:0471209627 "Deuchar EM (pg. 29)"] synonym: "glossopharyngeal nerve" RELATED [] xref: ZFA:0000668 is_a: XAO:0000429 ! cephalic nerve relationship: part_of XAO:0003197 ! gustatory system [Term] id: XAO:0003097 name: cranial nerve X def: "Cranial nerve that branches into the lateral (to body sense organs) and the intestino-accessorial (to the skin, muscles of shoulder, hyoid, larynx, gut, lungs, and heart)." [ISBN:0471209627 "Deuchar EM (pg. 29)"] synonym: "vagus nerve" RELATED [] xref: ZFA:0000453 is_a: XAO:0003089 ! cranial nerve relationship: part_of XAO:0003197 ! gustatory system [Term] id: XAO:0003098 name: cerebellum xref: ZFA:0000100 relationship: part_of XAO:0000015 ! hindbrain [Term] id: XAO:0003099 name: fourth ventricle synonym: "IVth ventricle" EXACT [] xref: ZFA:0000110 relationship: part_of XAO:0000015 ! hindbrain [Term] id: XAO:0003100 name: medulla oblongata xref: ZFA:0000545 relationship: part_of XAO:0000015 ! hindbrain [Term] id: XAO:0003101 name: spinal nerve is_a: XAO:0003047 ! nerve relationship: part_of XAO:0000178 ! peripheral nervous system [Term] id: XAO:0003102 name: transverse process relationship: part_of XAO:0003073 ! postcranial axial skeleton [Term] id: XAO:0003103 name: claw def: "Anatomical structure consisting of a small, pointed keratinized appendage at the end of each of the three inner toes of the hind limbs." [XB:curator "Xenbase"] relationship: part_of XAO:0003031 ! hind limb relationship: start_stage XAO:1000070 ! NF stage 58 [Term] id: XAO:0003104 name: myotome of head somite 1 is_a: XAO:0000315 ! myotome relationship: develops_from XAO:0000396 ! head somite 1 relationship: end_stage XAO:1000043 ! NF stage 27 [Term] id: XAO:0003105 name: myotome of head somite 2 is_a: XAO:0000315 ! myotome relationship: develops_from XAO:0000403 ! head somite 2 relationship: end_stage XAO:1000054 ! NF stage 42 [Term] id: XAO:0003106 name: myotome of head somite 3 is_a: XAO:0000315 ! myotome relationship: develops_from XAO:0000404 ! head somite 3 relationship: end_stage XAO:1000056 ! NF stage 44 [Term] id: XAO:0003107 name: myotome of head somite 4 is_a: XAO:0000315 ! myotome relationship: develops_from XAO:0000405 ! head somite 4 relationship: end_stage XAO:1000059 ! NF stage 47 [Term] id: XAO:0003108 name: myotome of trunk somite 1 is_a: XAO:0000315 ! myotome relationship: develops_from XAO:0000406 ! trunk somite 1 [Term] id: XAO:0003109 name: myotome of trunk somite 2 is_a: XAO:0000315 ! myotome relationship: develops_from XAO:0000407 ! trunk somite 2 [Term] id: XAO:0003110 name: myotome of trunk somite 3 is_a: XAO:0000315 ! myotome relationship: develops_from XAO:0000408 ! trunk somite 3 [Term] id: XAO:0003111 name: myotome of trunk somite 4 is_a: XAO:0000315 ! myotome relationship: develops_from XAO:0000409 ! trunk somite 4 [Term] id: XAO:0003112 name: sclerotome of head somite 4 is_a: XAO:0000397 ! sclerotome relationship: develops_from XAO:0000405 ! head somite 4 [Term] id: XAO:0003113 name: sclerotome of trunk somite 1 is_a: XAO:0000397 ! sclerotome relationship: develops_from XAO:0000406 ! trunk somite 1 [Term] id: XAO:0003114 name: sclerotome of trunk somite 2 is_a: XAO:0000397 ! sclerotome relationship: develops_from XAO:0000407 ! trunk somite 2 [Term] id: XAO:0003115 name: sclerotome of trunk somite 3 is_a: XAO:0000397 ! sclerotome relationship: develops_from XAO:0000408 ! trunk somite 3 [Term] id: XAO:0003116 name: sclerotome of trunk somite 4 is_a: XAO:0000397 ! sclerotome relationship: develops_from XAO:0000409 ! trunk somite 4 [Term] id: XAO:0003117 name: myotome of trunk somite 5 is_a: XAO:0000315 ! myotome relationship: develops_from XAO:0000410 ! trunk somite 5 [Term] id: XAO:0003118 name: myotome of trunk somite 6 is_a: XAO:0000315 ! myotome relationship: develops_from XAO:0000411 ! trunk somite 6 [Term] id: XAO:0003119 name: myotome of trunk somite 7 is_a: XAO:0000315 ! myotome relationship: develops_from XAO:0000412 ! trunk somite 7 [Term] id: XAO:0003120 name: myotome of trunk somite 8 is_a: XAO:0000315 ! myotome relationship: develops_from XAO:0000416 ! trunk somite 8 [Term] id: XAO:0003121 name: sclerotome of trunk somite 5 is_a: XAO:0000397 ! sclerotome relationship: develops_from XAO:0000410 ! trunk somite 5 [Term] id: XAO:0003122 name: sclerotome of trunk somite 6 is_a: XAO:0000397 ! sclerotome relationship: develops_from XAO:0000411 ! trunk somite 6 [Term] id: XAO:0003123 name: sclerotome of trunk somite 7 is_a: XAO:0000397 ! sclerotome relationship: develops_from XAO:0000412 ! trunk somite 7 [Term] id: XAO:0003124 name: sclerotome of trunk somite 8 is_a: XAO:0000397 ! sclerotome relationship: develops_from XAO:0000416 ! trunk somite 8 [Term] id: XAO:0003125 name: myotome of trunk somite 9 is_a: XAO:0000315 ! myotome relationship: develops_from XAO:0000417 ! trunk somite 9 [Term] id: XAO:0003126 name: sclerotome of trunk somite 9 is_a: XAO:0000397 ! sclerotome relationship: develops_from XAO:0000417 ! trunk somite 9 [Term] id: XAO:0003127 name: sclerotome of trunk somite 10 is_a: XAO:0000397 ! sclerotome relationship: develops_from XAO:0000418 ! trunk somite 10 [Term] id: XAO:0003128 name: myotome of trunk somite 10 is_a: XAO:0000315 ! myotome relationship: develops_from XAO:0000418 ! trunk somite 10 [Term] id: XAO:0003129 name: sclerotome of trunk somite 11 is_a: XAO:0000397 ! sclerotome relationship: develops_from XAO:0000419 ! trunk somite 11 [Term] id: XAO:0003130 name: myotome of trunk somite 11 is_a: XAO:0000315 ! myotome relationship: develops_from XAO:0000419 ! trunk somite 11 [Term] id: XAO:0003131 name: sclerotome of trunk somite 12 is_a: XAO:0000397 ! sclerotome relationship: develops_from XAO:0000420 ! trunk somite 12 [Term] id: XAO:0003132 name: myotome of trunk somite 12 is_a: XAO:0000315 ! myotome relationship: develops_from XAO:0000420 ! trunk somite 12 [Term] id: XAO:0003133 name: sclerotome of trunk somite 13 is_a: XAO:0000397 ! sclerotome relationship: develops_from XAO:0000421 ! trunk somite 13 [Term] id: XAO:0003134 name: myotome of trunk somite 13 is_a: XAO:0000315 ! myotome relationship: develops_from XAO:0000421 ! trunk somite 13 [Term] id: XAO:0003135 name: sclerotome of trunk somite 14 is_a: XAO:0000397 ! sclerotome relationship: develops_from XAO:0000422 ! trunk somite 14 [Term] id: XAO:0003136 name: myotome of trunk somite 14 is_a: XAO:0000315 ! myotome relationship: develops_from XAO:0000422 ! trunk somite 14 [Term] id: XAO:0003137 name: sclerotome of trunk somite 15 is_a: XAO:0000397 ! sclerotome relationship: develops_from XAO:0000423 ! trunk somite 15 [Term] id: XAO:0003138 name: myotome of trunk somite 15 is_a: XAO:0000315 ! myotome relationship: develops_from XAO:0000423 ! trunk somite 15 [Term] id: XAO:0003139 name: sclerotome of trunk somite 16 is_a: XAO:0000397 ! sclerotome relationship: develops_from XAO:0000424 ! trunk somite 16 [Term] id: XAO:0003140 name: myotome of trunk somite 16 is_a: XAO:0000315 ! myotome relationship: develops_from XAO:0000424 ! trunk somite 16 [Term] id: XAO:0003141 name: sclerotome of trunk somite 17 is_a: XAO:0000397 ! sclerotome relationship: develops_from XAO:0000425 ! trunk somite 17 [Term] id: XAO:0003142 name: myotome of trunk somite 17 is_a: XAO:0000315 ! myotome relationship: develops_from XAO:0000425 ! trunk somite 17 [Term] id: XAO:0003143 name: tail somite is_a: XAO:0000058 ! somite relationship: part_of XAO:0003026 ! tail [Term] id: XAO:0003144 name: amphibian papilla relationship: part_of XAO:0000194 ! membranous labyrinth [Term] id: XAO:0003145 name: basilar papilla relationship: part_of XAO:0000194 ! membranous labyrinth [Term] id: XAO:0003146 name: gonad def: "Reproductive organ that produces and releases eggs (ovary) or sperm (testis)." [ZFA:0000413] xref: ZFA:0000413 relationship: part_of XAO:0003025 ! trunk [Term] id: XAO:0003147 name: spermatozoon def: "A mature male germ cell that develops from a spermatid." [CL:0000019] synonym: "sperm" RELATED [] synonym: "spermatozoa" RELATED PLURAL [] xref: CL:0000019 is_a: XAO:0003150 ! gamete relationship: develops_from XAO:0003151 ! spermatid [Term] id: XAO:0003148 name: germ line cell xref: CL:0000039 is_a: XAO:0003012 ! cell [Term] id: XAO:0003149 name: primordial germ cell def: "Primitive cell type that is involved in the reproduction of the organism beginning with the sexual differentiation of the gonads at NF stage 52. In males specifically, it migrates from the genital ridge cortical region into the medullary tissue, where it forms spermatogonia. In females it is embedded in the cortical region and multiplies as oogonia." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 137)"] synonym: "PGC" EXACT [] synonym: "primitive germ cell" RELATED [] xref: CL:0000670 is_a: XAO:0003148 ! germ line cell relationship: develops_from XAO:0000233 ! germ plasm relationship: start_stage XAO:1000052 ! NF stage 40 [Term] id: XAO:0003150 name: gamete def: "A mature male or female germ cell." [NLM:gamete "MedlinePlus Medical Dictionary"] xref: CL:0000300 is_a: XAO:0003148 ! germ line cell [Term] id: XAO:0003151 name: spermatid xref: CL:0000018 is_a: XAO:0000111 ! germ cell relationship: develops_from XAO:0003019 ! spermatocyte [Term] id: XAO:0003152 name: immune system def: "Anatomical system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymphoid tissue, lymphocytes including the B cells and T cells, and antibodies." [NLM:immune+system "MedlinePlus Medical Dictionary"] xref: ZFA:0001159 is_a: XAO:0003002 ! anatomical system relationship: end_stage XAO:0000437 ! death [Term] id: XAO:0003153 name: larval immune system is_a: XAO:0003152 ! immune system relationship: end_stage XAO:1000078 ! NF stage 66 [Term] id: XAO:0003154 name: adult immune system is_a: XAO:0003152 ! immune system relationship: start_stage XAO:1000009 ! adult [Term] id: XAO:0003155 name: lymphocyte def: "A cell of the B cell, T cell, or natural killer cell lineage." [CL:0000542] xref: CL:0000542 is_a: XAO:0003012 ! cell relationship: part_of XAO:0003152 ! immune system [Term] id: XAO:0003156 name: natural killer cell synonym: "NK cell" EXACT [] xref: CL:0000623 is_a: XAO:0003155 ! lymphocyte [Term] id: XAO:0003157 name: T cell xref: CL:0000084 is_a: XAO:0003155 ! lymphocyte relationship: develops_from XAO:0003159 ! thymocyte [Term] id: XAO:0003158 name: B cell xref: CL:0000236 is_a: XAO:0003155 ! lymphocyte [Term] id: XAO:0003159 name: thymocyte is_a: XAO:0003155 ! lymphocyte relationship: part_of XAO:0000163 ! thymus [Term] id: XAO:0003160 name: anatomical cluster def: "Anatomical group that has its parts adjacent to one another." [CARO:0000041] xref: CARO:0000041 is_a: XAO:0003001 ! anatomical group relationship: end_stage XAO:0000437 ! death relationship: part_of XAO:0003004 ! whole organism relationship: start_stage XAO:1000001 ! NF stage 1 [Term] id: XAO:0003161 name: limb bud is_a: XAO:0003028 ! surface structure relationship: start_stage XAO:1000058 ! NF stage 46 [Term] id: XAO:0003162 name: acellular anatomical structure def: "Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue." [CARO:0000040] xref: CARO:0000040 is_a: XAO:0003000 ! anatomical structure relationship: end_stage XAO:0000437 ! death relationship: start_stage XAO:1000001 ! NF stage 1 [Term] id: XAO:0003163 name: basal lamina def: "Acellular anatomical structure that consists of a thin sheet of fibrous proteins that underlie and support the cells of an epithelium. It separates the cells of an epithelium from any underlying tissue." [CARO:0000065] xref: CARO:0000065 is_a: XAO:0003162 ! acellular anatomical structure relationship: end_stage XAO:0000437 ! death [Term] id: XAO:0003164 name: solid compound organ def: "Compound organ that does not contain macroscopic anatomical spaces." [CARO:0000074] xref: CARO:0000074 is_a: XAO:0003041 ! compound organ relationship: end_stage XAO:0000437 ! death [Term] id: XAO:0003165 name: cavitated compound organ def: "Compound organ that contains one or more macroscopic anatomical spaces." [CARO:0000072] xref: CARO:0000072 is_a: XAO:0003041 ! compound organ relationship: end_stage XAO:0000437 ! death [Term] id: XAO:0003166 name: appendicular skeleton def: "Skeletal structure that has as its parts the pectoral and pelvic girdles, which articulate with the axial skeleton, together with their associated limbs, the forelimbs and hind limbs." [AAO:0000747] xref: AAO:0000747 is_a: XAO:0003060 ! skeletal system [Term] id: XAO:0003167 name: fore metapodium is_obsolete: true [Term] id: XAO:0003168 name: hind mesopodium is_obsolete: true [Term] id: XAO:0003169 name: dermatocranium def: "Cranium which consists of dermally derived bones." [TAO:0000863] is_a: XAO:0003075 ! cranium [Term] id: XAO:0003170 name: neurocranium is_a: XAO:0003160 ! anatomical cluster relationship: part_of XAO:0003075 ! cranium [Term] id: XAO:0003171 name: orbital region def: "Anatomical cluster that is part of the cranium and provides structural support for the eye." [TAO:0001410] is_a: XAO:0003160 ! anatomical cluster relationship: part_of XAO:0003075 ! cranium [Term] id: XAO:0003172 name: olfactory region def: "Anatomical cluster that is located in the anterior region of the cranium and provides structural support for the olfactory organ." [TAO:0000351] is_a: XAO:0003160 ! anatomical cluster relationship: part_of XAO:0003075 ! cranium [Term] id: XAO:0003173 name: occipital region def: "Anatomical cluster that is located in the posterior region of the cranium and forms the margin of the foramen magnum and occipital condyles." [TAO:0001414] is_a: XAO:0003160 ! anatomical cluster relationship: part_of XAO:0003075 ! cranium [Term] id: XAO:0003174 name: sphenoid region def: "Anatomical cluster that forms the floor and side walls of the middle part of the cranium." [TAO:0000290] is_a: XAO:0003160 ! anatomical cluster relationship: part_of XAO:0003075 ! cranium [Term] id: XAO:0003175 name: otic region def: "Anatomical cluster that is a posterolateral part of the cranium and structurally supports the vestibuloauditory system." [TAO:0000189] is_a: XAO:0003160 ! anatomical cluster relationship: part_of XAO:0003075 ! cranium [Term] id: XAO:0003176 name: splanchnocranium def: "Regional skeletal system of the jaws, hyoid and branchial arches." [ZFA:0001216] xref: ZFA:0001216 is_a: XAO:0003075 ! cranium [Term] id: XAO:0003177 name: hyoid arch skeleton xref: ZFA:0001276 relationship: part_of XAO:0000098 ! hyoid arch relationship: part_of XAO:0003176 ! splanchnocranium [Term] id: XAO:0003178 name: dorsal hyoid arch skeleton relationship: part_of XAO:0003177 ! hyoid arch skeleton [Term] id: XAO:0003179 name: ventral hyoid arch skeleton relationship: part_of XAO:0003177 ! hyoid arch skeleton [Term] id: XAO:0003180 name: branchial arch skeleton xref: ZFA:0000095 relationship: part_of XAO:0000099 ! branchial arch relationship: part_of XAO:0003176 ! splanchnocranium [Term] id: XAO:0003181 name: branchial arch skeleton 1 is_a: XAO:0003180 ! branchial arch skeleton relationship: part_of XAO:0000447 ! branchial arch 1 [Term] id: XAO:0003182 name: branchial arch skeleton 2 is_a: XAO:0003180 ! branchial arch skeleton relationship: part_of XAO:0000449 ! branchial arch 2 [Term] id: XAO:0003183 name: branchial arch skeleton 3 is_a: XAO:0003180 ! branchial arch skeleton relationship: part_of XAO:0000451 ! branchial arch 3 [Term] id: XAO:0003184 name: branchial arch skeleton 4 is_a: XAO:0003180 ! branchial arch skeleton relationship: part_of XAO:0000453 ! branchial arch 4 [Term] id: XAO:0003185 name: anatomical direction is_a: XAO:0000000 ! Xenopus anatomical entity [Term] id: XAO:0003186 name: anatomical region is_a: XAO:0000000 ! Xenopus anatomical entity [Term] id: XAO:0003187 name: medial subset: anatomical_site_slim is_a: XAO:0003185 ! anatomical direction [Term] id: XAO:0003188 name: proximal subset: anatomical_site_slim is_a: XAO:0003185 ! anatomical direction [Term] id: XAO:0003189 name: distal subset: anatomical_site_slim is_a: XAO:0003185 ! anatomical direction [Term] id: XAO:0003190 name: anatomical space def: "Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures." [CARO:0000005] xref: CARO:0000005 is_a: XAO:0000000 ! Xenopus anatomical entity [Term] id: XAO:0003191 name: left atrium relationship: part_of XAO:0000064 ! heart [Term] id: XAO:0003192 name: right atrium relationship: part_of XAO:0000064 ! heart [Term] id: XAO:0003193 name: cardiac ventricle xref: ZFA:0000009 relationship: part_of XAO:0000064 ! heart [Term] id: XAO:0003194 name: sensory system def: "A part of the nervous system responsible for processing sensory information." [WIKI:Sensory_system "Wikipedia (en)"] xref: ZFA:0000282 is_a: XAO:0003002 ! anatomical system relationship: end_stage XAO:0000437 ! death relationship: part_of XAO:0000177 ! nervous system [Term] id: XAO:0003195 name: vestibuloauditory system def: "The sensory system used for balance and hearing." [XB:curator "Xenbase"] xref: ZFA:0001138 is_a: XAO:0003194 ! sensory system [Term] id: XAO:0003196 name: olfactory system def: "The sensory system used for olfaction (the sense of smell)." [WIKI:Olfactory_system "Wikipedia (en)"] xref: ZFA:0001149 is_a: XAO:0003194 ! sensory system [Term] id: XAO:0003197 name: gustatory system def: "The sensory system used for the sense of taste." [WIKI:Gustatory_system "Wikipedia (en)"] xref: ZFA:0001101 is_a: XAO:0003194 ! sensory system [Term] id: XAO:0003198 name: visual system def: "The sensory system used for sight." [XB:curator "Xenbase"] xref: ZFA:0001127 is_a: XAO:0003194 ! sensory system [Term] id: XAO:0003199 name: lymphatic system xref: ZFA:0000385 is_a: XAO:0003002 ! anatomical system [Term] id: XAO:0003200 name: gut epithelium xref: ZFA:0005123 is_a: XAO:0003045 ! epithelium relationship: part_of XAO:0000125 ! alimentary system [Term] id: XAO:0003201 name: oral epithelium xref: ZFA:0000816 is_a: XAO:0003045 ! epithelium relationship: part_of XAO:0003029 ! mouth [Term] id: XAO:0003202 name: pharyngeal epithelium xref: ZFA:0001174 is_a: XAO:0003045 ! epithelium [Term] id: XAO:0003203 name: dental epithelium xref: ZFA:0005134 is_a: XAO:0003045 ! epithelium [Term] id: XAO:0003204 name: neural tube xref: ZFA:0001135 is_a: XAO:0003042 ! embryonic structure [Term] id: XAO:0003205 name: chondrocyte def: "Polymorphic cell type that forms cartilage." [CL:0000138] xref: CL:0000138 is_a: XAO:0003012 ! cell relationship: part_of XAO:0000170 ! cartilage [Term] id: XAO:0003206 name: podocyte def: "Cell type that is a component of the glomus." [XB:curator "Xenbase"] xref: CL:0000653 is_a: XAO:0003012 ! cell relationship: part_of XAO:0000318 ! glomus [Term] id: XAO:0003207 name: carpus relationship: part_of XAO:0003030 ! forelimb relationship: part_of XAO:0003061 ! forelimb skeleton [Term] id: XAO:0003208 name: metacarpus relationship: part_of XAO:0003030 ! forelimb relationship: part_of XAO:0003061 ! forelimb skeleton [Term] id: XAO:0003209 name: radio-ulna synonym: "radioulna" EXACT [] synonym: "radius-ulna" EXACT [] relationship: part_of XAO:0003030 ! forelimb relationship: part_of XAO:0003061 ! forelimb skeleton [Term] id: XAO:0003210 name: humerus relationship: part_of XAO:0003030 ! forelimb relationship: part_of XAO:0003061 ! forelimb skeleton [Term] id: XAO:0003211 name: tarsus relationship: part_of XAO:0003031 ! hind limb relationship: part_of XAO:0003062 ! hind limb skeleton [Term] id: XAO:0003212 name: metatarsus relationship: part_of XAO:0003031 ! hind limb relationship: part_of XAO:0003062 ! hind limb skeleton [Term] id: XAO:0003213 name: tibia-fibula def: "Bone of the lower hind leg, which undergoes ossification from NF stage 56 to stage 66." [ISBN:0471209627 "Deuchar EM (pg. 123)"] relationship: part_of XAO:0003031 ! hind limb relationship: part_of XAO:0003062 ! hind limb skeleton [Term] id: XAO:0003214 name: femur def: "Proximal bone of the hind leg, which begins to ossify at NF stage 55." [ISBN:0471209627 "Deuchar EM (pg. 123)"] relationship: part_of XAO:0003031 ! hind limb relationship: part_of XAO:0003062 ! hind limb skeleton [Term] id: XAO:1000000 name: Xenopus developmental stage namespace: xenopus_developmental_stage [Term] id: XAO:1000001 name: NF stage 1 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 1; age 0 hr; corresponding to the following external morphological criteria: One cell stage, shortly after fertilization. Pigmentation darker ventrally than dorsally." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 163)"] synonym: "zygote" RELATED [] xref: ZFS:0000001 is_a: XAO:1000012 ! embryonic stage [Term] id: XAO:1000002 name: early tailbud namespace: xenopus_developmental_stage def: "The stages from Nieuwkoop and Faber stage 22 to stage 28." [ISBN:0815318960 "Nieuwkoop and Faber"] is_a: XAO:1000007 ! tailbud stage [Term] id: XAO:1000003 name: blastula namespace: xenopus_developmental_stage def: "The stages from 64-cell embryo to Nieuwkoop and Faber stage 9, during which the solid morula acquires an internal cavity." [ISBN:0471209627 "Deuchar EM (pg. 102)", ISBN:0815318960 "Nieuwkoop and Faber"] is_a: XAO:1000012 ! embryonic stage [Term] id: XAO:1000004 name: cleavage namespace: xenopus_developmental_stage def: "The stages from 2-cell to 64-cell embryo, during which the zygote undergoes synchronous divisions into 2, 4, 8, 16, etc. blastomeres." [ISBN:0471209627 "Deuchar EM (pg. 102)", ISBN:0815318960 "Nieuwkoop and Faber"] is_a: XAO:1000012 ! embryonic stage [Term] id: XAO:1000005 name: gastrula namespace: xenopus_developmental_stage def: "The stages from Nieuwkoop and Faber stage 10 to stage 12.5, during which gastrulation takes place, with a proportion of cells migrating below the surface of the embryo to form two inner layers (endoderm and mesoderm) and the cells which remain outside spreading over the whole surface of the embryo to form the ectoderm." [ISBN:0471209627 "Deuchar EM (pg. 102)", ISBN:0815318960 "Nieuwkoop and Faber"] is_a: XAO:1000012 ! embryonic stage [Term] id: XAO:1000006 name: neurula namespace: xenopus_developmental_stage def: "The stages from Nieuwkoop and Faber stage 13 to stage 21, during which the future nervous system appears as a thickened plate in dorsal ectoderm, the plate then rolling up at its sides to form a tube." [ISBN:0471209627 "Deuchar EM (pg. 104)", ISBN:0815318960 "Nieuwkoop and Faber"] is_a: XAO:1000012 ! embryonic stage [Term] id: XAO:1000007 name: tailbud stage namespace: xenopus_developmental_stage def: "Any of the developmental stages from Nieuwkoop and Faber stage 20 to stage 44 (feeding), including the beginning of hatching (NF stage 35/36)." [ISBN:0815318960 "Nieuwkoop and Faber"] is_a: XAO:1000012 ! embryonic stage [Term] id: XAO:1000008 name: tadpole namespace: xenopus_developmental_stage def: "The stages from feeding to the end of metamorphosis. Encompasses Weisz's first-form tadpole (equivalent to NF stages 45 to 49), second-form tadpole (NF 49 to 56) and third-form tadpole (NF 56 to 60-plus) stages." [ISBN:0471209627 "Deuchar EM (pg. 115-7)", ISSN:0003-276X "Weisz PB (1945)"] synonym: "larva" RELATED [] is_a: XAO:1000000 ! Xenopus developmental stage [Term] id: XAO:1000009 name: adult namespace: xenopus_developmental_stage def: "The stage of being a fully formed animal, following Nieuwkoop and Faber stage 66." [ISBN:0815318960 "Nieuwkoop and Faber"] is_a: XAO:1000000 ! Xenopus developmental stage [Term] id: XAO:1000010 name: juvenile namespace: xenopus_developmental_stage def: "The stage of being a sexually immature adult animal." [XB:curator "Xenbase"] relationship: part_of XAO:1000009 ! adult relationship: preceded_by XAO:1000078 ! NF stage 66 [Term] id: XAO:1000011 name: NF stage 2 (2-cell) namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 2; age 1 hr 30 min at 22-24 Celsius; corresponding to the following external morphological criteria: Advanced two cell stage. First cleavage groove has reached vegetal pole. Ventral side of blastomeres darker than dorsal side." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 163)"] synonym: "2-cell stage" EXACT [] xref: ZFS:0000002 relationship: part_of XAO:1000004 ! cleavage relationship: preceded_by XAO:1000028 ! NF stage 2- [Term] id: XAO:1000012 name: embryonic stage namespace: xenopus_developmental_stage def: "Any of the developmental stages from fertilization to feeding." [XB:curator "Xenbase"] is_a: XAO:1000000 ! Xenopus developmental stage [Term] id: XAO:1000013 name: NF stage 3 (4-cell) namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 3; age 2 hr at 22-24 Celsius; corresponding to the following external morphological criteria: Advanced four-cell stage. Second cleavage groove has reached vegetal pole. In animal view dorsal blastomeres usually smaller than ventral ones; the latter darker than the former." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 163)"] synonym: "4-cell stage" EXACT [] xref: ZFS:0000003 relationship: part_of XAO:1000004 ! cleavage relationship: preceded_by XAO:1000011 ! NF stage 2 (2-cell) [Term] id: XAO:1000014 name: NF stage 4 (8-cell) namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 4; age 2 hr 15 min at 22-24 Celsius; corresponding to the following external morphological criteria: Advanced eight cell stage. Dorsal micro- and macromeres usually smaller than ventral ones; dorsal micromeres less pigmented than ventral ones." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 163)"] synonym: "8-cell stage" EXACT [] xref: ZFS:0000004 relationship: part_of XAO:1000004 ! cleavage relationship: preceded_by XAO:1000013 ! NF stage 3 (4-cell) [Term] id: XAO:1000015 name: NF stage 5 (16-cell) namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 5; age 2 hr 45 min at 22-24 Celsius; corresponding to the following external morphological criteria: Advanced sixteen cell stage. Dorsal micromeres distinctly smaller and less pigmented than ventral ones. Macromeres entirely separated by cleavage grooves." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 163-4)"] synonym: "16-cell stage" EXACT [] xref: ZFS:0000005 relationship: part_of XAO:1000004 ! cleavage relationship: preceded_by XAO:1000014 ! NF stage 4 (8-cell) [Term] id: XAO:1000016 name: NF stage 6 (32-cell) namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 6; age 3 hr at 22-24 Celsius; corresponding to the following external morphological criteria: Advanced thirty-two cell stage. Distinction between dorsal and ventral micromeres as in preceding stage." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 164)"] synonym: "32-cell stage" EXACT [] xref: ZFS:0000006 relationship: part_of XAO:1000004 ! cleavage relationship: preceded_by XAO:1000015 ! NF stage 5 (16-cell) [Term] id: XAO:1000017 name: NF stage 7 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 7, 64-cell embryo; age 4 hr at 22-24 Celsius; corresponding to the following external morphological criteria: Large-cell blastula stage. In animal view about 10 micromeres along meridian." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 164)"] synonym: "64-cell stage" EXACT [] xref: ZFS:0000007 relationship: part_of XAO:1000003 ! blastula relationship: preceded_by XAO:1000029 ! NF stage 6.5 [Term] id: XAO:1000018 name: NF stage 8 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 8, 128-cell embryo; age 5 hr at 22-24 Celsius; corresponding to the following external morphological criteria: Medium-cell blastula stage. Surface not yet entirely smooth. Border of animal pigment cap more diffuse at dorsal than at lateral and ventral sides. Gradual transition in cell size from animal to vegetative pole." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 164)"] synonym: "128-cell stage" EXACT [] xref: ZFS:0000008 relationship: part_of XAO:1000003 ! blastula relationship: preceded_by XAO:1000017 ! NF stage 7 [Term] id: XAO:1000019 name: NF stage 9 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 9; age 7 hr at 22-24 Celsius; corresponding to the following external morphological criteria: Fine-cell blastula stage. Animal cells smaller at dorsal than at ventral side. Border between marginal zone and vegetative field distinct, particularly dorsally, owing to difference in cell size." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 164-5)"] relationship: part_of XAO:1000003 ! blastula relationship: preceded_by XAO:1000018 ! NF stage 8 [Term] id: XAO:1000020 name: NF stage 10 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 10; age 9 hr at 22-24 Celsius; corresponding to the following external morphological criteria: Initial gastrula stage. First indication of blastopore only by pigment concentration. No formation of groove." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 165)"] relationship: part_of XAO:1000005 ! gastrula relationship: preceded_by XAO:1000019 ! NF stage 9 [Term] id: XAO:1000021 name: NF stage 11 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 11; age 11 hr 45 min at 22-24 Celsius; corresponding to the following external morphological criteria: Horse-shoe-shaped blastopore stage. Blastopore groove surrounding about half of future yolk plug and indicated at its ventral side; future yolk plug often rounded rectangular, slightly elongated in dorso-ventral direction, diameter more than two-fifths of diameter of egg (plus or minus 50 degrees of circumference)." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 165)"] relationship: part_of XAO:1000005 ! gastrula relationship: preceded_by XAO:1000031 ! NF stage 10.5 [Term] id: XAO:1000022 name: NF stage 12 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 12; age 13 hr 15 min at 22-24 Celsius; corresponding to the following external morphological criteria: Medium yolk plug stage. Yolk plug circular; diameter somewhat less than one fourth of diameter of egg (plus or minus 25 degrees). More and less pigmented fields radiating from yolk plug." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 166)"] relationship: part_of XAO:1000005 ! gastrula relationship: preceded_by XAO:1000032 ! NF stage 11.5 [Term] id: XAO:1000023 name: NF stage 13 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 13; age 14 hr 45 min at 22-24 Celsius; corresponding to the following external morphological criteria: Slit-blastopore stage. Neural plate faintly delimited; slight elevation of its rostral part and slight flattening of its caudal part. Caudal part of median groove formed." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 166)"] relationship: part_of XAO:1000006 ! neurula relationship: preceded_by XAO:1000033 ! NF stage 12.5 [Term] id: XAO:1000024 name: NF stage 14 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 14; age 16 hr 15 min at 22-24 Celsius; corresponding to the following external morphological criteria: Neural plate stage. Cerebral part of neural plate bent downwards, with median elevation at rostral end of median groove. Initial elevation of neural folds, most pronounced in future nucal region. Blastopore always slit-shaped." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 167)"] relationship: part_of XAO:1000006 ! neurula relationship: preceded_by XAO:1000023 ! NF stage 13 [Term] id: XAO:1000025 name: NF stage 15 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 15; age 17 hr 30 min at 22-24 Celsius; corresponding to the following external morphological criteria: Early neural fold stage. Presumptive cement gland faintly circumscribed. Anterior part of neural plate roundish. Neural folds distinct, except medio-rostrally; initial formation of sharp inner ridges on neural folds in rhombencephalic region." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 167)"] relationship: part_of XAO:1000006 ! neurula relationship: preceded_by XAO:1000024 ! NF stage 14 [Term] id: XAO:1000026 name: NF stage 16 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 16; age 18 hr 15 min at 22-24 Celsius; corresponding to the following external morphological criteria: Mid neural fold stage. Anterior part of neural plate rectangular; darkly pigmented eye anlagen present; neural plate sharply constricted in the middle. Inner ridges on neural folds forming angle of about 90 degrees with neural plate in rhombencephalic region." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 167)"] relationship: part_of XAO:1000006 ! neurula relationship: preceded_by XAO:1000025 ! NF stage 15 [Term] id: XAO:1000027 name: NF stage 17 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 17; age 18 hr 45 min at 22-24 Celsius; corresponding to the following external morphological criteria: Late neural fold stage. Anterior part of neural plate oblong triangular, angles formed by eye anlagen. Neural folds approaching each other from blastopore up to anterior trunk region." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 168)"] relationship: part_of XAO:1000006 ! neurula relationship: preceded_by XAO:1000026 ! NF stage 16 [Term] id: XAO:1000028 name: NF stage 2- namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 2-; age 1 hr 15 min at 22-24 Celsius; corresponding to the following external morphological criteria: Beginning of first cleavage. First cleavage groove has not yet reached vegetal pole." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 163)"] relationship: part_of XAO:1000004 ! cleavage relationship: preceded_by XAO:1000001 ! NF stage 1 [Term] id: XAO:1000029 name: NF stage 6.5 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 6.5; age 3 hr 30 min at 22-24 Celsius; corresponding to the following external morphological criteria: Morula stage. About 48 blastomeres. In animal view about 6 micromeres along meridian." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 164)"] synonym: "morula" RELATED [ISBN:0815318960 "Nieuwkoop and Faber"] relationship: part_of XAO:1000004 ! cleavage relationship: preceded_by XAO:1000016 ! NF stage 6 (32-cell) [Term] id: XAO:1000030 name: NF stage 10.25 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 10.25; age 10 hr at 22-24 Celsius; corresponding to the following external morphological criteria: Early gastrula stage. First formation of dorsal blastopore groove; groove still straight." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 165)"] synonym: "NF stage 10+" EXACT [] relationship: part_of XAO:1000005 ! gastrula relationship: preceded_by XAO:1000020 ! NF stage 10 [Term] id: XAO:1000031 name: NF stage 10.5 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 10.5; age 11 hr at 22-24 Celsius; corresponding to the following external morphological criteria: Crescent-shaped blastopore stage. Blastopore groove angular. Vegetal field slightly decreased in size, ventral border of future yolk plug indicated by pigment contraction." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 165)"] relationship: part_of XAO:1000005 ! gastrula relationship: preceded_by XAO:1000030 ! NF stage 10.25 [Term] id: XAO:1000032 name: NF stage 11.5 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 11.5; age 12 hr 30 min at 22-24 Celsius; corresponding to the following external morphological criteria: Large yolk plug stage. Blastopore groove closed ventrally; yolk plug not yet quite circular. At ventral side concentrated superficial pigment still visible. Diameter of yolk plug about a third of diameter of egg (plus or minus 40 degrees)." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 166)"] relationship: part_of XAO:1000005 ! gastrula relationship: preceded_by XAO:1000021 ! NF stage 11 [Term] id: XAO:1000033 name: NF stage 12.5 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 12.5; age 14 hr 15 min at 22-24 Celsius; corresponding to the following external morphological criteria: Small yolk plug stage. Future position of neural plate and median groove indicated by darker pigment lines. Yolk plug usually ovoid, variable in size." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 166)"] relationship: part_of XAO:1000005 ! gastrula relationship: preceded_by XAO:1000022 ! NF stage 12 [Term] id: XAO:1000034 name: NF stage 18 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 18; age 19 hr 45 min at 22-24 Celsius; corresponding to the following external morphological criteria: Neural groove stage. Anterior part of neural plate narrow, more or less club-shaped, often narrower towards rostral end. Parallel neural folds in trunk region very close to each other, not yet touching." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 168)"] relationship: part_of XAO:1000006 ! neurula relationship: preceded_by XAO:1000027 ! NF stage 17 [Term] id: XAO:1000035 name: NF stage 19 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 19; age 20 hr 45 min at 22-24 Celsius; corresponding to the following external morphological criteria: Initial neural tube stage. Neural folds touching each other, except for inconstant openings at anterior and posterior end and behind nucal region. Considerable lateral extension of brain. Lateral outline of embryo still convex." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 168)"] relationship: part_of XAO:1000006 ! neurula relationship: preceded_by XAO:1000034 ! NF stage 18 [Term] id: XAO:1000036 name: NF stage 20 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 20; age 21 hr 45 min at 22-24 Celsius; corresponding to the following external morphological criteria: Neural folds fused, suture still present. The two eye anlagen showing through dumb-bell-shaped, eyes hardly protruding. Beginning of stretching of embryos. Lateral outline flat." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 168)"] relationship: part_of XAO:1000006 ! neurula relationship: preceded_by XAO:1000035 ! NF stage 19 [Term] id: XAO:1000037 name: NF stage 21 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 21; age 22 hr 30 min at 22-24 Celsius; corresponding to the following external morphological criteria: Suture of neural tube completely closed. Delimitation of frontal field by pigment lines. Primary eye vesicles showing through in the form of two separate, obliquely placed oval spots; beginning of protrusion of eyes. Lateral outline of embryo just becoming concave, ventral outline flat." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 169)"] relationship: part_of XAO:1000006 ! neurula relationship: preceded_by XAO:1000036 ! NF stage 20 [Term] id: XAO:1000038 name: NF stage 22 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 22; age 24 hr at 22-24 Celsius; corresponding to the following external morphological criteria: Distinct protrusion of eyes. Initial groove between jaw- and gill-areas only at latero-dorsal side. Lateral and ventral outlines of embryo slightly concave. Anal opening displaced to ventral side. Vitelline membrane becoming wider." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 169)"] relationship: part_of XAO:1000002 ! early tailbud relationship: preceded_by XAO:1000037 ! NF stage 21 [Term] id: XAO:1000039 name: NF stage 23 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 23; age 1 day, 45 min at 22-24 Celsius; corresponding to the following external morphological criteria: Jaw- and gill-areas completely separated by groove. Ventral outline of embryo more concave." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 169)"] relationship: part_of XAO:1000002 ! early tailbud relationship: preceded_by XAO:1000038 ! NF stage 22 [Term] id: XAO:1000040 name: NF stage 24 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 24; age 1 day, 2 hr 15 min at 22-24 Celsius; corresponding to the following external morphological criteria: Eyes protruding less far laterally than gill-area. Gill-area more prominent than jaw-area, gill-area not yet grooved. Ventral outline of embryo nicked. Tail bud discernible. Initial motor reactions to external stimulation." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 170)"] relationship: part_of XAO:1000002 ! early tailbud relationship: preceded_by XAO:1000039 ! NF stage 23 [Term] id: XAO:1000041 name: NF stage 25 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 25; age 1 day, 3 hr 30 min at 22-24 Celsius; corresponding to the following external morphological criteria: Eyes protruding equally far or further laterally than gill-area. Gill-area grooved. Invagination of otic vesicle indicated by pigment spot. Beginning of fin formation." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 170)"] relationship: part_of XAO:1000002 ! early tailbud relationship: preceded_by XAO:1000040 ! NF stage 24 [Term] id: XAO:1000042 name: NF stage 26 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 26; age 1 day, 5 hr 30 min at 22-24 Celsius; corresponding to the following external morphological criteria: otic vesicle protruding. Pronephros distinctly visible. Myotomes showing through for the first time. Fin somewhat broadened at dorso-caudal end of body. Beginning of spontaneous movements." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 170)"] relationship: part_of XAO:1000002 ! early tailbud relationship: preceded_by XAO:1000041 ! NF stage 25 [Term] id: XAO:1000043 name: NF stage 27 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 27; age 1 day, 7 hr 15 min at 22-24 Celsius; corresponding to the following external morphological criteria: Lateral flattening of eyes. Fin transluscent, except for region behind anus. Tail bud formation accentuated in lateral outline." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 170)"] relationship: part_of XAO:1000002 ! early tailbud relationship: preceded_by XAO:1000042 ! NF stage 26 [Term] id: XAO:1000044 name: NF stage 28 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 28; age 1 day, 8 hr 30 min at 22-24 Celsius; corresponding to the following external morphological criteria: Fin extending up to anus. Fin broadened and distinctly divided into outer transparent and inner translucent band." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 171)"] relationship: part_of XAO:1000002 ! early tailbud relationship: preceded_by XAO:1000043 ! NF stage 27 [Term] id: XAO:1000045 name: NF stage 29 and 30 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 29 and 30; age 1 day, 11 hr at 22-24 Celsius; corresponding to the following external morphological criteria: Gray eye cup showing through for the first time. Fin transparent up to the base over its whole length. Tail bud distinct." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 171)"] relationship: part_of XAO:1000080 ! late tailbud relationship: preceded_by XAO:1000044 ! NF stage 28 [Term] id: XAO:1000046 name: NF stage 31 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 31; age 1 day, 13 hr 30 min at 22-24 Celsius; corresponding to the following external morphological criteria: Tail bud equally long as broad." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 171)"] relationship: part_of XAO:1000080 ! late tailbud relationship: preceded_by XAO:1000045 ! NF stage 29 and 30 [Term] id: XAO:1000047 name: NF stage 32 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 32; age 1 day, 16 hr at 22-24 Celsius; corresponding to the following external morphological criteria: Eye cup horse-shoe-shaped, standing out distinctly. Length of tail bud about 1.5 times its breadth." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 172)"] relationship: part_of XAO:1000080 ! late tailbud relationship: preceded_by XAO:1000046 ! NF stage 31 [Term] id: XAO:1000048 name: NF stage 33 and 34 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 33 and 34; age 1 day, 20 hr 30 min at 22-24 Celsius; corresponding to the following external morphological criteria: Stomodeal invagination a shallow vertical groove. Dorsal part of eye more pigmented than ventral part; distinct melanophores in dorsal part. Melanophores appearing dorsally on the head and laterally in a row extending from just below the pronephros backwards. Length of tail bud about twice its breadth. Beginning of heart beat." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 172)"] relationship: part_of XAO:1000080 ! late tailbud relationship: preceded_by XAO:1000047 ! NF stage 32 [Term] id: XAO:1000049 name: NF stage 35 and 36 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 35 and 36; age 2 days, 2 hr at 22-24 Celsius; corresponding to the following external morphological criteria: Stomodeal invagination roundish. Eye entirely black, choroid fissure nearly closed. Formation of two gill rudiments, anterior one nipple-shaped. Melanophores appearing on back. Posterior outline of proctodeum still curved. Length of tail bud about three times its breadth. Beginning of hatching." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 173)"] relationship: part_of XAO:1000080 ! late tailbud relationship: preceded_by XAO:1000048 ! NF stage 33 and 34 [Term] id: XAO:1000050 name: NF stage 37 and 38 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 37 and 38; age 2 days, 5 hr 30 min at 22-24 Celsius; corresponding to the following external morphological criteria: Stomodeal invagination much deeper, opening round. Both gill rudiments nipple-shaped, a branch of the anterior one indicated. Posterior outline of proctodeum straight, forming very obtuse angle with ventral border of tail myotomes. Melanophores spreading over tail." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 173)"] relationship: part_of XAO:1000080 ! late tailbud relationship: preceded_by XAO:1000049 ! NF stage 35 and 36 [Term] id: XAO:1000051 name: NF stage 39 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 39; age 2 days, 8 hr 30 min at 22-24 Celsius; corresponding to the following external morphological criteria: Melanophores appearing around nasal pits. Opening of stomodeal invagination transversely elongated. Melanophores on back arranged in a superficial and a deeper layer. Outlines of proctodeum and tail myotomes forming angle of about 135 degrees. Melanophores appearing along ventral edge of tail musculature." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 174)"] relationship: part_of XAO:1000080 ! late tailbud relationship: preceded_by XAO:1000050 ! NF stage 37 and 38 [Term] id: XAO:1000052 name: NF stage 40 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 40; age 2 days, 18 hr at 22-24 Celsius; corresponding to the following external morphological criteria: Mouth broken through. Length of gills about twice their breadth, posterior one sometimes also showing a branch. Outlines of proctodeum and tail myotomes forming angles of 90 degrees. Beginning of blood circulation in gills." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 174)"] relationship: part_of XAO:1000080 ! late tailbud relationship: preceded_by XAO:1000051 ! NF stage 39 [Term] id: XAO:1000053 name: NF stage 41 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 41; age 3 days, 4 hr at 22-24 Celsius; corresponding to the following external morphological criteria: Gills broader and flatter, more laterally directed. Formation of a left-rostral and a right-caudal furrow in yolk mass; torsion of interjacent part about 45 degrees; formation of conical proctodeum, forming angle of about 60 degrees with tail myotomes. Formation of fin rostral to proctodeum; ventral outline of yolk mass and proctodeum a smooth concave line." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 175)"] relationship: part_of XAO:1000080 ! late tailbud relationship: preceded_by XAO:1000052 ! NF stage 40 [Term] id: XAO:1000054 name: NF stage 42 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 42; age 3 days, 8 hr at 22-24 Celsius; corresponding to the following external morphological criteria: Beginning of formation of opercular folds. Torsion of intestine about 90 degrees; proctodeum connected with yolk mass by short horizontal intestinal tube." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 175)"] relationship: part_of XAO:1000080 ! late tailbud relationship: preceded_by XAO:1000053 ! NF stage 41 [Term] id: XAO:1000055 name: NF stage 43 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 43; age 3 days, 15 hr at 22-24 Celsius; corresponding to the following external morphological criteria: Lateral line system becoming visible externally. Cement gland losing its pigment. Torsion of intestine about 180 degrees; proctodeum narrower, arched or S-shaped." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 176)"] relationship: part_of XAO:1000080 ! late tailbud relationship: preceded_by XAO:1000054 ! NF stage 42 [Term] id: XAO:1000056 name: NF stage 44 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 44; age 3 days, 20 hr at 22-24 Celsius; corresponding to the following external morphological criteria: Appearance of tentacle rudiments. Opercular folds protruding further. Coiling part of intestine showing S-shaped loop; torsion about 360 degrees. Blood-circulation in gills usually ceased (gills smaller)." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 176)"] relationship: part_of XAO:1000080 ! late tailbud relationship: preceded_by XAO:1000055 ! NF stage 43 [Term] id: XAO:1000057 name: NF stage 45 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 45; age 4 days, 2 hr at 22-24 Celsius; corresponding to the following external morphological criteria: Operculum partly covering gills, edge still straight. Intestine spiralized in ventral aspects, showing 1.5 revolutions. Beginning of feeding." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 177)"] relationship: part_of XAO:1000089 ! premetamorphosis relationship: preceded_by XAO:1000056 ! NF stage 44 [Term] id: XAO:1000058 name: NF stage 46 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 46; age 4 days, 10 hr at 22-24 Celsius; corresponding to the following external morphological criteria: Edge of operculum becoming convex. Xantophores appearing on eye and abdomen. Intestine showing 2 to 2.5 revolutions. Hindlimb bud visible for the first time." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 177)"] relationship: part_of XAO:1000089 ! premetamorphosis relationship: preceded_by XAO:1000057 ! NF stage 45 [Term] id: XAO:1000059 name: NF stage 47 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 47; age 5 days, 12 hr at 22-24 Celsius; corresponding to the following external morphological criteria: Tentacles larger. Edge of operculum forming quarter of a circle. Xantophores forming opaque layer on abdomen. Intestine showing 2.5 to 3.5 revolutions. Hindlimb bud more distinct." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 177)"] relationship: part_of XAO:1000089 ! premetamorphosis relationship: preceded_by XAO:1000058 ! NF stage 46 [Term] id: XAO:1000060 name: NF stage 48 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 48; age 7.5 days at 22-24 Celsius; corresponding to the following external morphological criteria: Beginning of pigmentation around n. acusticus. Forelimb bud visible for the first time. Shining gold-coloured abdomen. Hindlimb bud semicircular in lateral aspect." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 178)"] relationship: part_of XAO:1000089 ! premetamorphosis relationship: preceded_by XAO:1000059 ! NF stage 47 [Term] id: XAO:1000061 name: NF stage 49 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 49; age about 12 days at 22-24 Celsius; corresponding to the following external morphological criteria: Melanophores usually appearing around thymus gland and nerves and blood vessels of head; xantophores appearing on pericard. Forelimb bud distinct. Hindlimb bud somewhat longer, distal outline still circular, no constrictions at base. Melanophores appearing on dorsal and ventral fin." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 178)"] relationship: part_of XAO:1000089 ! premetamorphosis relationship: preceded_by XAO:1000060 ! NF stage 48 [Term] id: XAO:1000062 name: NF stage 50 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 50; age about 15 days at 22-24 Celsius; corresponding to the following external morphological criteria: Forelimb bud somewhat oval-shaped in dorsal aspect. Hindlimb bud longer than broad, constricted at base, distal outline somewhat conical." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 179)"] relationship: part_of XAO:1000089 ! premetamorphosis relationship: preceded_by XAO:1000061 ! NF stage 49 [Term] id: XAO:1000063 name: NF stage 51 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 51; age about 17 days at 22-24 Celsius; corresponding to the following external morphological criteria: Tentacles much longer. Forelimb bud oval-shaped in lateral aspect. Hindlimb bud conical in shape, its length about 1.5 times its breadth; melanophores appearing on it." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 180)"] relationship: part_of XAO:1000089 ! premetamorphosis relationship: preceded_by XAO:1000062 ! NF stage 50 [Term] id: XAO:1000064 name: NF stage 52 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 52; age about 21 days at 22-24 Celsius; corresponding to the following external morphological criteria: Forelimb bud irregularly conical. Hindlimb bud showing first indication of ankle constriction and first sign of flattening of foot." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 180)"] relationship: part_of XAO:1000089 ! premetamorphosis relationship: preceded_by XAO:1000063 ! NF stage 51 [Term] id: XAO:1000065 name: NF stage 53 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 53; age about 24 days at 22-24 Celsius; corresponding to the following external morphological criteria: Fore- and hindlimbs in paddle stage. Hindlimb whithout foot somewhat longer than broad; 4th and 5th toe indicated." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 181)"] relationship: part_of XAO:1000089 ! premetamorphosis relationship: preceded_by XAO:1000064 ! NF stage 52 [Term] id: XAO:1000066 name: NF stage 54 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 54; age about 26 days at 22-24 Celsius; corresponding to the following external morphological criteria: All four fingers indicated; edge of hand slightly scalloped between fingers; melanophores appearing on forelimb. Length of hindlimb without foot nearly twice its breadth; all five toes indicated, the second only very slightly." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 181)"] relationship: part_of XAO:1000089 ! premetamorphosis relationship: preceded_by XAO:1000065 ! NF stage 53 [Term] id: XAO:1000067 name: NF stage 55 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 55; age about 32 days at 22-24 Celsius; corresponding to the following external morphological criteria: Hand pronated about 90 degrees; free parts of fingers about equally long as broad. Length of hindlimb without foot about 3 times its breadth; length of cartilages of 4th and 5th toe about 4 times their breadth." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 181)"] relationship: part_of XAO:1000090 ! prometamorphosis relationship: preceded_by XAO:1000066 ! NF stage 54 [Term] id: XAO:1000068 name: NF stage 56 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 56; age about 38 days at 22-24 Celsius; corresponding to the following external morphological criteria: Elbow and wrist clearly indicated; length of free parts of fingers 3 to 4 times their breadth. Length of cartilages of 4th and 5th toe about 6 times their breadth." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 182)"] relationship: part_of XAO:1000090 ! prometamorphosis relationship: preceded_by XAO:1000067 ! NF stage 55 [Term] id: XAO:1000069 name: NF stage 57 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 57; age about 41 days at 22-24 Celsius; corresponding to the following external morphological criteria: Pigment-free spot appearing above \"Stirnorgan\". Angle of elbow more than 90 degrees; fingers stretched out in forelimb atrium, their length about 7 times their breadth." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 183)"] relationship: part_of XAO:1000090 ! prometamorphosis relationship: preceded_by XAO:1000068 ! NF stage 56 [Term] id: XAO:1000070 name: NF stage 58 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 58; age about 44 days at 22-24 Celsius; corresponding to the following external morphological criteria: Forelimbs broken through. Guanophores appearing on abdomen and thighs (adult skin areas). All three claws present on hindlimbs." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 183)"] relationship: part_of XAO:1000091 ! climax relationship: preceded_by XAO:1000069 ! NF stage 57 [Term] id: XAO:1000071 name: NF stage 59 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 59; age about 45 days at 22-24 Celsius; corresponding to the following external morphological criteria: Tentacles beginning to shrivel up. Stretched forelimb reaching down to base of hindlimb. Guanophores appearing near base of forelimb (adult skin area); anterior border of adult skin area on abdomen not yet sharp; appearance of irregular dark spots on back." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 184)"] relationship: part_of XAO:1000091 ! climax relationship: preceded_by XAO:1000070 ! NF stage 58 [Term] id: XAO:1000072 name: NF stage 60 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 60; age about 46 days at 22-24 Celsius; corresponding to the following external morphological criteria: N. olfactorius still longer than bulbus olfactorius. Guanophores appearing on lower jaw (adult skin area). Openings of gill chambers still wide. Distal half of fingers of stretched forelimb extending beyond base of hindlimb; forelimb still situated behind level of heart. Adult skin area of base of forelimb covered with guanophores; anterior border of adult skin area on abdomen sharper, reaching up to heart." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 184)"] relationship: part_of XAO:1000091 ! climax relationship: preceded_by XAO:1000071 ! NF stage 59 [Term] id: XAO:1000073 name: NF stage 61 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 61; age about 48 days at 22-24 Celsius; corresponding to the following external morphological criteria: Head narrower. Tentacles considerably shortened, mostly curved backwards. Length of n. olfactorius equal to diameter of bulbus olfactorius. 4th arterial arch seen just in front of adult skin area of forelimb. Openings of gill chambers considerably narrowed. Forelimb at level of posterior half of heart. Adult skin area on abdomen covering posterior half of heart. Fins considerably reduced." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 185)"] relationship: part_of XAO:1000091 ! climax relationship: preceded_by XAO:1000072 ! NF stage 60 [Term] id: XAO:1000074 name: NF stage 62 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 62; age about 49 days at 22-24 Celsius; corresponding to the following external morphological criteria: Head still somewhat broader than cranial part of trunk. Tentacles short, straight. N. olfactorius shorter than diameter of bulbus olfactorius. Corner of mouth still in front of eye. Thymus gland somewhat protruding. 3rd arterial arch (\"larval aorta\") seen at distance of its own diameter in front of adult skin area of forelimb. Opening of operculum reduced to curved slit. Forelimb at level of middle of heart. Anterior border of adult skin area on abdomen entirely sharp, mostly nicked medially. Ventral fin disappeared from abdomen." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 186)"] relationship: part_of XAO:1000091 ! climax relationship: preceded_by XAO:1000073 ! NF stage 61 [Term] id: XAO:1000075 name: NF stage 63 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 63; age about 51 days at 22-24 Celsius; corresponding to the following external morphological criteria: Head narrower than trunk. Tentacles mostly disappeared. Corner of mouth at level of caudal border of eye. \"Larval aorta\" and thymus gland no longer externally visible. Operculum closed. Adult skin areas on abdomen and lower jaw separated by narrow band of larval skin. Forelimb at level of anterior half of heart. Fin mostly perforated near anus. Tail still slightly longer than body." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 186)"] relationship: part_of XAO:1000091 ! climax relationship: preceded_by XAO:1000074 ! NF stage 62 [Term] id: XAO:1000076 name: NF stage 64 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 64; age about 53 days at 22-24 Celsius; corresponding to the following external morphological criteria: Corner of mouth well behind eye. Various adult skin areas joined almost everywhere, borderlines still clearly visible. Length of tail (from anus) is a third of body length." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 187)"] relationship: part_of XAO:1000091 ! climax relationship: preceded_by XAO:1000075 ! NF stage 63 [Term] id: XAO:1000077 name: NF stage 65 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 65; age about 54 days at 22-24 Celsius; corresponding to the following external morphological criteria: Borderlines between adult skin areas partly disappeared. Tail oblong triangular in dorsal aspect, length abouth one tenth of body length." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 188)"] relationship: part_of XAO:1000091 ! climax relationship: preceded_by XAO:1000076 ! NF stage 64 [Term] id: XAO:1000078 name: NF stage 66 namespace: xenopus_developmental_stage def: "Nieuwkoop and Faber stage 66; age about 58 days at 22-24 Celsius; corresponding to the following external morphological criteria: Border lines between adult skin areas disappeared. Tail only a very small triangle, no longer visible from ventral side." [ISBN:0815318960 "Nieuwkoop and Faber (pg. 188)"] relationship: part_of XAO:1000091 ! climax relationship: preceded_by XAO:1000077 ! NF stage 65 [Term] id: XAO:1000079 name: metamorphosing tadpole namespace: xenopus_developmental_stage def: "The stages from Nieuwkoop and Faber stage 54 to stage 66." [ISBN:0815318960 "Nieuwkoop and Faber"] relationship: part_of XAO:1000008 ! tadpole [Term] id: XAO:1000080 name: late tailbud namespace: xenopus_developmental_stage def: "The stages from Nieuwkoop and Faber stage 29/30 to stage 44." [ISBN:0815318960 "Nieuwkoop and Faber"] is_a: XAO:1000007 ! tailbud stage [Term] id: XAO:1000081 name: unspecified stage namespace: xenopus_developmental_stage comment: If an anatomical term has a starts_during or ends_during relationship to this stage term, this information is either unknown or has not yet been curated. is_a: XAO:1000000 ! Xenopus developmental stage [Term] id: XAO:1000082 name: unfertilized egg namespace: xenopus_developmental_stage is_a: XAO:1000000 ! Xenopus developmental stage [Term] id: XAO:1000089 name: premetamorphosis namespace: xenopus_developmental_stage def: "The period during which limb bud growth occurs, covering Nieuwkoop and Faber stage 45 to stage 54." [ISBN:0124554032 "Dodd MHI and Dodd JM (1976)"] relationship: part_of XAO:1000008 ! tadpole [Term] id: XAO:1000090 name: prometamorphosis namespace: xenopus_developmental_stage def: "The period during which toe differentiation and rapid hind limb growth continue, covering Nieuwkoop and Faber stage 55 to stage 57." [ISBN:0124554032 "Dodd MHI and Dodd JM (1976)"] relationship: part_of XAO:1000079 ! metamorphosing tadpole [Term] id: XAO:1000091 name: climax namespace: xenopus_developmental_stage def: "The period during which tail resorption occurs, covering Nieuwkoop and Faber stage 58 to stage 66." [ISBN:0124554032 "Dodd MHI and Dodd JM (1976)"] relationship: part_of XAO:1000079 ! metamorphosing tadpole [Typedef] id: develops_from name: develops from is_transitive: true [Typedef] id: end_stage name: ends during [Typedef] id: part_of name: part of is_transitive: true [Typedef] id: preceded_by name: preceded by is_transitive: true [Typedef] id: start_stage name: starts during