{

• "id": "http://purl.obolibrary.org/obo/CHEBI_75393",
• "prefLabel": "Y-27632",
• -
  "subClassOf": [
  • "http://purl.obolibrary.org/obo/CHEBI_50994",
  • "http://purl.obolibrary.org/obo/CHEBI_26421",
  • "http://purl.obolibrary.org/obo/CHEBI_29347"
  ],
• "obsolete": false,
• -
  "definition": [
  • "A monocarboxylic acid amide that is trans-[(1R)-1-aminoethyl]cyclohexanecarboxamide in which one of the nitrogens of the aminocarbony group is substituted by a pyridine nucleus. It has been shown to exhibit inhibitory activity against Rho-associated protein kinase (ROCK) enzyme."
  ],
• -
  "synonym": [
  • "(R)-(+)-trans-N-(4-pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide",
  • "4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-1-carboxamide",
  • "Y 27632",
  • "trans-4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexanecarboxamide"
  ],
• -
  "parents": [
  • -
    {
    • "id": "http://purl.obolibrary.org/obo/CHEBI_50994",
    • "prefLabel": "primary amino compound",
    • -
      "subClassOf": [
      • "http://purl.obolibrary.org/obo/CHEBI_50047"
      ],
    • "obsolete": false,
    • -
      "definition": [
      • "A compound formally derived from ammonia by replacing one hydrogen atom by an organyl group."
      ],
    • -
      "synonym": [
      • "primary amino compounds"
      ],
    • "cui": [ ],
    • "semanticType": [ ],
    • "notation": "CHEBI:50994",
    • -
      "label": [
      • "primary amino compound"
      ],
    • "prefixIRI": null,
    • "xref": null,
    • "created": null,
    • "modified": null,
    • "@id": "http://purl.obolibrary.org/obo/CHEBI_50994",
    • "@type": "http://www.w3.org/2002/07/owl#Class",
    • -
      "links": {
      • "self": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_50994",
      • "ontology": "https://data.bioontology.org/ontologies/BERO",
      • "children": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_50994/children",
      • "parents": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_50994/parents",
      • "descendants": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_50994/descendants",
      • "ancestors": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_50994/ancestors",
      • "instances": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_50994/instances",
      • "tree": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_50994/tree",
      • "notes": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_50994/notes",
      • "mappings": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_50994/mappings",
      • "ui": "http://bioportal.bioontology.org/ontologies/BERO?p=classes&conceptid=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_50994",
      • -
        "@context": {
        • "self": "http://www.w3.org/2002/07/owl#Class",
        • "ontology": "http://data.bioontology.org/metadata/Ontology",
        • "children": "http://www.w3.org/2002/07/owl#Class",
        • "parents": "http://www.w3.org/2002/07/owl#Class",
        • "descendants": "http://www.w3.org/2002/07/owl#Class",
        • "ancestors": "http://www.w3.org/2002/07/owl#Class",
        • "instances": "http://data.bioontology.org/metadata/Instance",
        • "tree": "http://www.w3.org/2002/07/owl#Class",
        • "notes": "http://data.bioontology.org/metadata/Note",
        • "mappings": "http://data.bioontology.org/metadata/Mapping",
        • "ui": "http://www.w3.org/2002/07/owl#Class"
        }
      },
    • -
      "@context": {
      • "@vocab": "http://data.bioontology.org/metadata/",
      • "label": "http://www.w3.org/2000/01/rdf-schema#label",
      • "prefLabel": "http://www.w3.org/2004/02/skos/core#prefLabel",
      • "synonym": "http://www.w3.org/2004/02/skos/core#altLabel",
      • "definition": "http://www.w3.org/2004/02/skos/core#definition",
      • "obsolete": "http://www.w3.org/2002/07/owl#deprecated",
      • "notation": "http://www.w3.org/2004/02/skos/core#notation",
      • "prefixIRI": "http://data.bioontology.org/metadata/prefixIRI",
      • "subClassOf": "http://www.w3.org/2000/01/rdf-schema#subClassOf",
      • "semanticType": "http://bioportal.bioontology.org/ontologies/umls/hasSTY",
      • "cui": "http://bioportal.bioontology.org/ontologies/umls/cui",
      • "xref": "http://www.geneontology.org/formats/oboInOwl#hasDbXref",
      • "created": "http://purl.org/dc/terms/created",
      • "modified": "http://purl.org/dc/terms/modified",
      • "@language": "en"
      }
    },
  • -
    {
    • "id": "http://purl.obolibrary.org/obo/CHEBI_26421",
    • "prefLabel": "pyridines",
    • -
      "subClassOf": [
      • "http://purl.obolibrary.org/obo/CHEBI_38101",
      • "http://purl.obolibrary.org/obo/CHEBI_25693"
      ],
    • "obsolete": false,
    • -
      "definition": [
      • "Any organonitrogen heterocyclic compound based on a pyridine skeleton and its substituted derivatives."
      ],
    • "synonym": [ ],
    • "cui": [ ],
    • "semanticType": [ ],
    • "notation": "CHEBI:26421",
    • -
      "label": [
      • "pyridines"
      ],
    • "prefixIRI": null,
    • "xref": null,
    • "created": null,
    • "modified": null,
    • "@id": "http://purl.obolibrary.org/obo/CHEBI_26421",
    • "@type": "http://www.w3.org/2002/07/owl#Class",
    • -
      "links": {
      • "self": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_26421",
      • "ontology": "https://data.bioontology.org/ontologies/BERO",
      • "children": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_26421/children",
      • "parents": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_26421/parents",
      • "descendants": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_26421/descendants",
      • "ancestors": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_26421/ancestors",
      • "instances": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_26421/instances",
      • "tree": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_26421/tree",
      • "notes": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_26421/notes",
      • "mappings": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_26421/mappings",
      • "ui": "http://bioportal.bioontology.org/ontologies/BERO?p=classes&conceptid=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_26421",
      • -
        "@context": {
        • "self": "http://www.w3.org/2002/07/owl#Class",
        • "ontology": "http://data.bioontology.org/metadata/Ontology",
        • "children": "http://www.w3.org/2002/07/owl#Class",
        • "parents": "http://www.w3.org/2002/07/owl#Class",
        • "descendants": "http://www.w3.org/2002/07/owl#Class",
        • "ancestors": "http://www.w3.org/2002/07/owl#Class",
        • "instances": "http://data.bioontology.org/metadata/Instance",
        • "tree": "http://www.w3.org/2002/07/owl#Class",
        • "notes": "http://data.bioontology.org/metadata/Note",
        • "mappings": "http://data.bioontology.org/metadata/Mapping",
        • "ui": "http://www.w3.org/2002/07/owl#Class"
        }
      },
    • -
      "@context": {
      • "@vocab": "http://data.bioontology.org/metadata/",
      • "label": "http://www.w3.org/2000/01/rdf-schema#label",
      • "prefLabel": "http://www.w3.org/2004/02/skos/core#prefLabel",
      • "synonym": "http://www.w3.org/2004/02/skos/core#altLabel",
      • "definition": "http://www.w3.org/2004/02/skos/core#definition",
      • "obsolete": "http://www.w3.org/2002/07/owl#deprecated",
      • "notation": "http://www.w3.org/2004/02/skos/core#notation",
      • "prefixIRI": "http://data.bioontology.org/metadata/prefixIRI",
      • "subClassOf": "http://www.w3.org/2000/01/rdf-schema#subClassOf",
      • "semanticType": "http://bioportal.bioontology.org/ontologies/umls/hasSTY",
      • "cui": "http://bioportal.bioontology.org/ontologies/umls/cui",
      • "xref": "http://www.geneontology.org/formats/oboInOwl#hasDbXref",
      • "created": "http://purl.org/dc/terms/created",
      • "modified": "http://purl.org/dc/terms/modified",
      • "@language": "en"
      }
    },
  • -
    {
    • "id": "http://purl.obolibrary.org/obo/CHEBI_29347",
    • "prefLabel": "monocarboxylic acid amide",
    • -
      "subClassOf": [
      • "http://purl.obolibrary.org/obo/CHEBI_37622"
      ],
    • "obsolete": false,
    • -
      "definition": [
      • "A carboxamide derived from a monocarboxylic acid."
      ],
    • -
      "synonym": [
      • "monocarboxylic acid amides"
      ],
    • "cui": [ ],
    • "semanticType": [ ],
    • "notation": "CHEBI:29347",
    • -
      "label": [
      • "monocarboxylic acid amide"
      ],
    • "prefixIRI": null,
    • "xref": null,
    • "created": null,
    • "modified": null,
    • "@id": "http://purl.obolibrary.org/obo/CHEBI_29347",
    • "@type": "http://www.w3.org/2002/07/owl#Class",
    • -
      "links": {
      • "self": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_29347",
      • "ontology": "https://data.bioontology.org/ontologies/BERO",
      • "children": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_29347/children",
      • "parents": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_29347/parents",
      • "descendants": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_29347/descendants",
      • "ancestors": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_29347/ancestors",
      • "instances": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_29347/instances",
      • "tree": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_29347/tree",
      • "notes": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_29347/notes",
      • "mappings": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_29347/mappings",
      • "ui": "http://bioportal.bioontology.org/ontologies/BERO?p=classes&conceptid=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_29347",
      • -
        "@context": {
        • "self": "http://www.w3.org/2002/07/owl#Class",
        • "ontology": "http://data.bioontology.org/metadata/Ontology",
        • "children": "http://www.w3.org/2002/07/owl#Class",
        • "parents": "http://www.w3.org/2002/07/owl#Class",
        • "descendants": "http://www.w3.org/2002/07/owl#Class",
        • "ancestors": "http://www.w3.org/2002/07/owl#Class",
        • "instances": "http://data.bioontology.org/metadata/Instance",
        • "tree": "http://www.w3.org/2002/07/owl#Class",
        • "notes": "http://data.bioontology.org/metadata/Note",
        • "mappings": "http://data.bioontology.org/metadata/Mapping",
        • "ui": "http://www.w3.org/2002/07/owl#Class"
        }
      },
    • -
      "@context": {
      • "@vocab": "http://data.bioontology.org/metadata/",
      • "label": "http://www.w3.org/2000/01/rdf-schema#label",
      • "prefLabel": "http://www.w3.org/2004/02/skos/core#prefLabel",
      • "synonym": "http://www.w3.org/2004/02/skos/core#altLabel",
      • "definition": "http://www.w3.org/2004/02/skos/core#definition",
      • "obsolete": "http://www.w3.org/2002/07/owl#deprecated",
      • "notation": "http://www.w3.org/2004/02/skos/core#notation",
      • "prefixIRI": "http://data.bioontology.org/metadata/prefixIRI",
      • "subClassOf": "http://www.w3.org/2000/01/rdf-schema#subClassOf",
      • "semanticType": "http://bioportal.bioontology.org/ontologies/umls/hasSTY",
      • "cui": "http://bioportal.bioontology.org/ontologies/umls/cui",
      • "xref": "http://www.geneontology.org/formats/oboInOwl#hasDbXref",
      • "created": "http://purl.org/dc/terms/created",
      • "modified": "http://purl.org/dc/terms/modified",
      • "@language": "en"
      }
    }
  ],
• "cui": [ ],
• "semanticType": [ ],
• "notation": "CHEBI:75393",
• -
  "label": [
  • "Y-27632"
  ],
• "prefixIRI": null,
• "xref": "Reaxys:9134889",
• "created": null,
• "modified": null,
• -
  "properties": {
  • -
    "http://www.geneontology.org/formats/oboInOwl#hasDbXref": [
    • "Reaxys:9134889",
    • "PMID:10686302",
    • "PMID:17157292",
    • "CAS:146986-50-7",
    • "PMID:17428993",
    • "Wikipedia:Y-27632",
    • "DrugBank:DB08756",
    • "PMID:17105828",
    • "PMID:10973620"
    ],
  • -
    "http://www.w3.org/2004/02/skos/core#notation": [
    • "CHEBI:75393"
    ],
  • -
    "http://www.geneontology.org/formats/oboInOwl#inSubset": [
    • "http://purl.obolibrary.org/obo/chebi#3_STAR"
    ],
  • -
    "http://purl.obolibrary.org/obo/chebi/inchi": [
    • "InChI=1S/C14H21N3O/c1-10(15)11-2-4-12(5-3-11)14(18)17-13-6-8-16-9-7-13/h6-12H,2-5,15H2,1H3,(H,16,17,18)/t10-,11-,12-/m1/s1"
    ],
  • -
    "http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym": [
    • "(R)-(+)-trans-N-(4-pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide",
    • "4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-1-carboxamide",
    • "Y 27632"
    ],
  • -
    "http://www.geneontology.org/formats/oboInOwl#id": [
    • "CHEBI:75393"
    ],
  • -
    "http://purl.obolibrary.org/obo/chebi/charge": [
    • "0"
    ],
  • -
    "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace": [
    • "chebi_ontology"
    ],
  • -
    "http://purl.obolibrary.org/obo/IAO_0000115": [
    • "A monocarboxylic acid amide that is trans-[(1R)-1-aminoethyl]cyclohexanecarboxamide in which one of the nitrogens of the aminocarbony group is substituted by a pyridine nucleus. It has been shown to exhibit inhibitory activity against Rho-associated protein kinase (ROCK) enzyme."
    ],
  • -
    "http://www.w3.org/2000/01/rdf-schema#label": [
    • "Y-27632"
    ],
  • -
    "http://purl.obolibrary.org/obo/chebi/formula": [
    • "C14H21N3O"
    ],
  • -
    "http://www.w3.org/2000/01/rdf-schema#subClassOf": [
    • "http://purl.obolibrary.org/obo/CHEBI_50994",
    • "http://purl.obolibrary.org/obo/CHEBI_26421",
    • "http://purl.obolibrary.org/obo/CHEBI_29347"
    ],
  • -
    "http://purl.obolibrary.org/obo/chebi/inchikey": [
    • "IYOZTVGMEWJPKR-IJLUTSLNSA-N"
    ],
  • -
    "http://purl.obolibrary.org/obo/chebi/mass": [
    • "247.33600"
    ],
  • -
    "http://purl.obolibrary.org/obo/chebi/monoisotopicmass": [
    • "247.16846"
    ],
  • -
    "http://www.w3.org/1999/02/22-rdf-syntax-ns#type": [
    • "http://www.w3.org/2002/07/owl#Class"
    ],
  • -
    "https://data.bioontology.org/metadata/def/prefLabel": [
    • "Y-27632"
    ],
  • -
    "http://purl.obolibrary.org/obo/chebi/smiles": [
    • "C[C@@H](N)[C@H]1CC[C@@H](CC1)C(=O)Nc1ccncc1"
    ],
  • -
    "http://purl.obolibrary.org/obo/RO_0000087": [
    • "http://purl.obolibrary.org/obo/CHEBI_50925"
    ],
  • -
    "http://www.geneontology.org/formats/oboInOwl#hasExactSynonym": [
    • "trans-4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexanecarboxamide"
    ],
  • -
    "http://purl.obolibrary.org/obo/RO_0000053": [
    • "http://purl.obolibrary.org/obo/CHEBI_50925"
    ],
  • -
    "http://purl.obolibrary.org/obo/IAO_0000118": [
    • "(R)-(+)-trans-N-(4-pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide",
    • "4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-1-carboxamide",
    • "Y 27632",
    • "trans-4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexanecarboxamide"
    ]
  },
• "@id": "http://purl.obolibrary.org/obo/CHEBI_75393",
• "@type": "http://www.w3.org/2002/07/owl#Class",
• -
  "links": {
  • "self": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_75393",
  • "ontology": "https://data.bioontology.org/ontologies/BERO",
  • "children": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_75393/children",
  • "parents": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_75393/parents",
  • "descendants": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_75393/descendants",
  • "ancestors": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_75393/ancestors",
  • "instances": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_75393/instances",
  • "tree": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_75393/tree",
  • "notes": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_75393/notes",
  • "mappings": "https://data.bioontology.org/ontologies/BERO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_75393/mappings",
  • "ui": "http://bioportal.bioontology.org/ontologies/BERO?p=classes&conceptid=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_75393",
  • -
    "@context": {
    • "self": "http://www.w3.org/2002/07/owl#Class",
    • "ontology": "http://data.bioontology.org/metadata/Ontology",
    • "children": "http://www.w3.org/2002/07/owl#Class",
    • "parents": "http://www.w3.org/2002/07/owl#Class",
    • "descendants": "http://www.w3.org/2002/07/owl#Class",
    • "ancestors": "http://www.w3.org/2002/07/owl#Class",
    • "instances": "http://data.bioontology.org/metadata/Instance",
    • "tree": "http://www.w3.org/2002/07/owl#Class",
    • "notes": "http://data.bioontology.org/metadata/Note",
    • "mappings": "http://data.bioontology.org/metadata/Mapping",
    • "ui": "http://www.w3.org/2002/07/owl#Class"
    }
  },
• -
  "@context": {
  • "@vocab": "http://data.bioontology.org/metadata/",
  • "label": "http://www.w3.org/2000/01/rdf-schema#label",
  • "prefLabel": "http://www.w3.org/2004/02/skos/core#prefLabel",
  • "synonym": "http://www.w3.org/2004/02/skos/core#altLabel",
  • "definition": "http://www.w3.org/2004/02/skos/core#definition",
  • "obsolete": "http://www.w3.org/2002/07/owl#deprecated",
  • "notation": "http://www.w3.org/2004/02/skos/core#notation",
  • "prefixIRI": "http://data.bioontology.org/metadata/prefixIRI",
  • "parents": "http://www.w3.org/2000/01/rdf-schema#parents",
  • "subClassOf": "http://www.w3.org/2000/01/rdf-schema#subClassOf",
  • "semanticType": "http://bioportal.bioontology.org/ontologies/umls/hasSTY",
  • "cui": "http://bioportal.bioontology.org/ontologies/umls/cui",
  • "xref": "http://www.geneontology.org/formats/oboInOwl#hasDbXref",
  • "created": "http://purl.org/dc/terms/created",
  • "modified": "http://purl.org/dc/terms/modified",
  • "@language": "en"
  }

}