1 90 0 https://w3id.org/biolink/vocab/DiseaseOrPhenotypicFeature disease or phenotypic feature 'disease or phenotypic feature' SubClassOf 'thing with taxon' https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#synthesis synthesis https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#mutation+rate mutation rate https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#nitrosation nitrosation https://w3id.org/biolink/vocab/MolecularControlMechanismQualifierEnum#potentiation potentiation https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#abundance abundance https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#lipidation lipidation https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#methylation methylation https://w3id.org/biolink/vocab/ChemicalOrGeneOrGeneProductFormEnum#polymorphism polymorphism https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalPartQualifierEnum#enhancer enhancer https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#transport transport https://w3id.org/biolink/vocab/DirectionQualifierEnum#upregulate upregulate https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#reduction reduction https://w3id.org/biolink/vocab/MolecularControlMechanismQualifierEnum#positive+allosteric+modulation positive allosteric modulation https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#acylation acylation https://w3id.org/biolink/vocab/VariableStateQualifierEnum variable_state_qualifier_enum 'variable_state_qualifier_enum' EquivalentTo 'present' https://w3id.org/biolink/vocab/MolecularControlMechanismQualifierEnum molecular_control_mechanism_qualifier_enum 'molecular_control_mechanism_qualifier_enum' EquivalentTo 'agonism' or 'antagonism' or 'antibody inhibitor' or 'binding' or 'inactivation' or 'inhibition' or 'inverse agonism' or 'molecular channel blockage' or 'molecular channel opening' or 'negative allosteric modulation' or 'neutralization' or 'positive allosteric modulation' or 'potentiation' https://w3id.org/biolink/vocab/MolecularControlMechanismQualifierEnum#inhibition inhibition https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#farnesylation farnesylation https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalPartQualifierEnum#5'+UTR 5' UTR https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#phosphorylation phosphorylation https://w3id.org/biolink/vocab/MolecularControlMechanismQualifierEnum#antagonism antagonism https://w3id.org/biolink/vocab/MolecularControlMechanismQualifierEnum#agonism agonism https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#palmitoylation palmitoylation https://w3id.org/biolink/vocab/VariableStateQualifierEnum#present present https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#sumoylation sumoylation https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#glucuronidation glucuronidation https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalPartQualifierEnum#exon exon https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#metabolic+processing metabolic processing https://w3id.org/biolink/vocab/ChemicalEntityDerivativeEnum#metabolite metabolite https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#alkylation alkylation https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#molecular+modification molecular modification https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#carboxylation carboxylation https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#sulfation sulfation https://w3id.org/biolink/vocab/RelativeTimingQualifierEnum relative_timing_qualifier_enum 'relative_timing_qualifier_enum' EquivalentTo 'future' https://w3id.org/biolink/vocab/MolecularControlMechanismQualifierEnum#inactivation inactivation https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#degredation degredation https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#glutathionylation glutathionylation https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#ethylation ethylation https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#ADP-ribosylation ADP-ribosylation https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#geranoylation geranoylation https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#acetylation acetylation https://w3id.org/biolink/vocab/ChemicalEntityDerivativeEnum chemical_entity_derivative_enum 'chemical_entity_derivative_enum' EquivalentTo 'metabolite' https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#N-linked+glycosylation N-linked glycosylation https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#hydrolisis hydrolisis https://w3id.org/biolink/vocab/MolecularControlMechanismQualifierEnum#antibody+inhibitor antibody inhibitor https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#carbamoylation carbamoylation https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalPartQualifierEnum#3'+UTR 3' UTR https://w3id.org/biolink/vocab/MolecularControlMechanismQualifierEnum#molecular+channel+blockage molecular channel blockage https://w3id.org/biolink/vocab/MolecularControlMechanismQualifierEnum#binding binding https://w3id.org/biolink/vocab/MolecularControlMechanismQualifierEnum#negative+allosteric+modulation negative allosteric modulation https://w3id.org/biolink/vocab/ChemicalOrGeneOrGeneProductFormEnum#modified+form modified form https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#nucleotidylation nucleotidylation https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#amination amination https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#stability stability https://w3id.org/biolink/vocab/DirectionQualifierEnum direction_qualifier_enum 'direction_qualifier_enum' EquivalentTo 'decreases' or 'downregulate' or 'increases' or 'upregulate' https://w3id.org/biolink/vocab/ChemicalEntityOrGeneOrGeneProductRegulatesGeneAssociation chemical entity or gene or gene product regulates gene association 'chemical entity or gene or gene product regulates gene association' SubClassOf http://www.w3.org/1999/02/22-rdf-syntax-ns#object exactly 1 'gene or gene product' 'chemical entity or gene or gene product regulates gene association' SubClassOf http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate exactly 1 'predicate type' 'chemical entity or gene or gene product regulates gene association' SubClassOf https://w3id.org/biolink/vocab/object_direction_qualifier max 1 'direction_qualifier_enum' 'chemical entity or gene or gene product regulates gene association' SubClassOf http://www.w3.org/1999/02/22-rdf-syntax-ns#subject exactly 1 'chemical entity or gene or gene product' 'chemical entity or gene or gene product regulates gene association' SubClassOf 'association' https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalPartQualifierEnum#promoter promoter https://w3id.org/biolink/vocab/DirectionQualifierEnum#decreases decreases https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#glycosylation glycosylation https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#localization localization https://w3id.org/biolink/vocab/ChemicalOrGeneOrGeneProductFormEnum#mutant+form mutant form https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#ribosylation ribosylation https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#prenylation prenylation https://w3id.org/biolink/vocab/ChemicalOrGeneOrGeneProductFormEnum chemical_or_gene_or_gene_product_form_enum 'chemical_or_gene_or_gene_product_form_enum' EquivalentTo 'SNP' or 'analog' or 'modified form' or 'mutant form' or 'polymorphism' https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#myristoylation myristoylation https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum gene_or_gene_product_or_chemical_entity_aspect_enum 'gene_or_gene_product_or_chemical_entity_aspect_enum' EquivalentTo 'ADP-ribosylation' or 'N-linked glycosylation' or 'O-linked glycosylation' or 'abundance' or 'acetylation' or 'activity' or 'acylation' or 'alkylation' or 'amination' or 'carbamoylation' or 'carboxylation' or 'cleavage' or 'degredation' or 'ethylation' or 'expression' or 'farnesylation' or 'geranoylation' or 'glucuronidation' or 'glutathionylation' or 'glycation' or 'glycosylation' or 'hydrolisis' or 'hydroxylation' or 'lipidation' or 'localization' or 'metabolic processing' or 'methylation' or 'molecular modification' or 'mutation rate' or 'myristoylation' or 'nitrosation' or 'nucleotidylation' or 'oxidation' or 'palmitoylation' or 'phosphorylation' or 'prenylation' or 'reduction' or 'ribosylation' or 'secretion' or 'stability' or 'sulfation' or 'sumoylation' or 'synthesis' or 'transport' or 'ubiquitination' or 'uptake' https://w3id.org/biolink/vocab/NamedThingAssociatedWithLikelihoodOfNamedThingAssociation named thing associated with likelihood of named thing association 'named thing associated with likelihood of named thing association' SubClassOf http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate exactly 1 'predicate type' 'named thing associated with likelihood of named thing association' SubClassOf https://w3id.org/biolink/vocab/subject_location_qualifier max 1 'ontology class' 'named thing associated with likelihood of named thing association' SubClassOf https://w3id.org/biolink/vocab/subject_variable_state_qualifier max 1 'variable_state_qualifier_enum' 'named thing associated with likelihood of named thing association' SubClassOf https://w3id.org/biolink/vocab/subject_aspect_qualifier max 1 https://w3id.org/linkml/String 'named thing associated with likelihood of named thing association' SubClassOf https://w3id.org/biolink/vocab/object_aspect_qualifier max 1 https://w3id.org/linkml/String 'named thing associated with likelihood of named thing association' SubClassOf https://w3id.org/biolink/vocab/object_variable_state_qualifier max 1 'variable_state_qualifier_enum' 'named thing associated with likelihood of named thing association' SubClassOf 'association' 'named thing associated with likelihood of named thing association' SubClassOf https://w3id.org/biolink/vocab/object_location_qualifier max 1 'ontology class' https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#O-linked+glycosylation O-linked glycosylation https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#oxidation oxidation https://w3id.org/biolink/vocab/MolecularControlMechanismQualifierEnum#neutralization neutralization https://w3id.org/biolink/vocab/ChemicalOrGeneOrGeneProductFormEnum#SNP SNP https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#uptake uptake https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#activity activity https://w3id.org/biolink/vocab/ChemicalOrGeneOrGeneProductFormEnum#analog analog https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalPartQualifierEnum#polyA+tail polyA tail https://w3id.org/biolink/vocab/DirectionQualifierEnum#increases increases https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#secretion secretion https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalPartQualifierEnum gene_or_gene_product_or_chemical_part_qualifier_enum 'gene_or_gene_product_or_chemical_part_qualifier_enum' EquivalentTo '3' UTR' or '5' UTR' or 'enhancer' or 'exon' or 'intron' or 'polyA tail' or 'promoter' https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#cleavage cleavage https://w3id.org/biolink/vocab/ChemicalGeneInteractionAssociation chemical gene interaction association 'chemical gene interaction association' SubClassOf https://w3id.org/biolink/vocab/object_context_qualifier max 1 'anatomical entity' 'chemical gene interaction association' SubClassOf https://w3id.org/biolink/vocab/subject_derivative_qualifier max 1 'chemical_entity_derivative_enum' 'chemical gene interaction association' SubClassOf http://www.w3.org/1999/02/22-rdf-syntax-ns#object exactly 1 'gene or gene product' 'chemical gene interaction association' SubClassOf http://www.w3.org/1999/02/22-rdf-syntax-ns#subject exactly 1 'chemical entity' 'chemical gene interaction association' SubClassOf https://w3id.org/biolink/vocab/interaction_mechanism_qualifier max 1 'molecular_control_mechanism_qualifier_enum' 'chemical gene interaction association' SubClassOf https://w3id.org/biolink/vocab/anatomical_context_qualifier max 1 'anatomical entity' 'chemical gene interaction association' SubClassOf 'association' 'chemical gene interaction association' SubClassOf https://w3id.org/biolink/vocab/subject_context_qualifier max 1 'anatomical entity' 'chemical gene interaction association' SubClassOf https://w3id.org/biolink/vocab/object_form_or_variant_qualifier max 1 'chemical_or_gene_or_gene_product_form_enum' 'chemical gene interaction association' SubClassOf https://w3id.org/biolink/vocab/subject_part_qualifier max 1 'gene_or_gene_product_or_chemical_part_qualifier_enum' 'chemical gene interaction association' SubClassOf http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate exactly 1 'predicate type' 'chemical gene interaction association' SubClassOf https://w3id.org/biolink/vocab/subject_form_or_variant_qualifier max 1 'chemical_or_gene_or_gene_product_form_enum' 'chemical gene interaction association' SubClassOf https://w3id.org/biolink/vocab/object_part_qualifier max 1 'gene_or_gene_product_or_chemical_part_qualifier_enum' https://w3id.org/biolink/vocab/MolecularControlMechanismQualifierEnum#molecular+channel+opening molecular channel opening https://w3id.org/biolink/vocab/ChemicalAffectsGeneAssociation chemical affects gene association 'chemical affects gene association' SubClassOf https://w3id.org/biolink/vocab/anatomical_context_qualifier max 1 'anatomical entity' 'chemical affects gene association' SubClassOf https://w3id.org/biolink/vocab/subject_derivative_qualifier max 1 'chemical_entity_derivative_enum' 'chemical affects gene association' SubClassOf https://w3id.org/biolink/vocab/effect_mechanism_qualifier max 1 'molecular_control_mechanism_qualifier_enum' 'chemical affects gene association' SubClassOf https://w3id.org/biolink/vocab/object_direction_qualifier max 1 'direction_qualifier_enum' 'chemical affects gene association' SubClassOf https://w3id.org/biolink/vocab/subject_aspect_qualifier max 1 https://w3id.org/linkml/String 'chemical affects gene association' SubClassOf https://w3id.org/biolink/vocab/object_form_or_variant_qualifier max 1 'chemical_or_gene_or_gene_product_form_enum' 'chemical affects gene association' SubClassOf https://w3id.org/biolink/vocab/subject_context_qualifier max 1 'anatomical entity' 'chemical affects gene association' SubClassOf https://w3id.org/biolink/vocab/object_context_qualifier max 1 'anatomical entity' 'chemical affects gene association' SubClassOf http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate exactly 1 'predicate type' 'chemical affects gene association' SubClassOf https://w3id.org/biolink/vocab/subject_direction_qualifier max 1 'direction_qualifier_enum' 'chemical affects gene association' SubClassOf https://w3id.org/biolink/vocab/subject_form_or_variant_qualifier max 1 'chemical_or_gene_or_gene_product_form_enum' 'chemical affects gene association' SubClassOf https://w3id.org/biolink/vocab/subject_part_qualifier max 1 'gene_or_gene_product_or_chemical_part_qualifier_enum' 'chemical affects gene association' SubClassOf http://www.w3.org/1999/02/22-rdf-syntax-ns#object exactly 1 'gene or gene product' 'chemical affects gene association' SubClassOf https://w3id.org/biolink/vocab/qualified_predicate max 1 https://w3id.org/linkml/String 'chemical affects gene association' SubClassOf 'association' 'chemical affects gene association' SubClassOf http://www.w3.org/1999/02/22-rdf-syntax-ns#subject exactly 1 'chemical entity' 'chemical affects gene association' SubClassOf https://w3id.org/biolink/vocab/object_aspect_qualifier max 1 'gene_or_gene_product_or_chemical_entity_aspect_enum' 'chemical affects gene association' SubClassOf https://w3id.org/biolink/vocab/object_part_qualifier max 1 'gene_or_gene_product_or_chemical_part_qualifier_enum' https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#ubiquitination ubiquitination https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#hydroxylation hydroxylation https://w3id.org/biolink/vocab/MolecularControlMechanismQualifierEnum#inverse+agonism inverse agonism https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalPartQualifierEnum#intron intron https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#glycation glycation https://w3id.org/biolink/vocab/DirectionQualifierEnum#downregulate downregulate https://w3id.org/biolink/vocab/RelativeTimingQualifierEnum#future future https://w3id.org/biolink/vocab/GeneOrGeneProductOrChemicalEntityAspectEnum#expression expression