Class ID,Preferred Label,Synonyms,Definitions,Obsolete,CUI,Semantic Types,Parents,Created in,Documentation,Example,has format,has function,has identifier,has input,has output,has topic,http://data.bioontology.org/metadata/prefixIRI,http://edamontology.org/noClue,http://purl.obolibrary.org/obo/date,http://purl.obolibrary.org/obo/default-relationship-id-prefix,http://purl.obolibrary.org/obo/edam#bioinformatics,http://purl.obolibrary.org/obo/edam#data,http://purl.obolibrary.org/obo/edam#edam,http://purl.obolibrary.org/obo/edam#events,http://purl.obolibrary.org/obo/edam#formats,http://purl.obolibrary.org/obo/edam#identifiers,http://purl.obolibrary.org/obo/edam#obsolete,http://purl.obolibrary.org/obo/edam#operations,http://purl.obolibrary.org/obo/edam#topics,http://purl.obolibrary.org/obo/idspace,http://purl.obolibrary.org/obo/is_anti_symmetric,http://purl.obolibrary.org/obo/is_metadata_tag,http://purl.obolibrary.org/obo/is_reflexive,http://purl.obolibrary.org/obo/is_symmetric,http://purl.obolibrary.org/obo/namespace,http://purl.obolibrary.org/obo/transitive_over,http://purl.org/dc/elements/1.1/creator,http://purl.org/dc/elements/1.1/format,http://purl.org/dc/elements/1.1/title,http://usefulinc.com/ns/doap#Version,http://www.geneontology.org/formats/oboInOwl#consider,http://www.geneontology.org/formats/oboInOwl#hasAlternativeId,http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym,http://www.geneontology.org/formats/oboInOwl#hasDbXref,http://www.geneontology.org/formats/oboInOwl#hasDefinition,http://www.geneontology.org/formats/oboInOwl#hasExactSynonym,http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym,http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym,http://www.geneontology.org/formats/oboInOwl#hasSubset,http://www.geneontology.org/formats/oboInOwl#inSubset,http://www.geneontology.org/formats/oboInOwl#isCyclic,http://www.geneontology.org/formats/oboInOwl#replacedBy,http://www.geneontology.org/formats/oboInOwl#savedBy,http://www.geneontology.org/formats/oboInOwl#SubsetProperty,http://xmlns.com/foaf/0.1/page,is format of,is function of,is identifier of,is input of,is output of,is topic of,Obsolete since,Regular expression
http://edamontology.org/topic_3438,Critical thinking,,Topic concerning the objective analysis and evaluation of an issue in order to form a judgement.,false,,,http://edamontology.org/topic_3364,1.4,,,,,,,,,edamontology:topic_3438,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the objective analysis and evaluation of an issue in order to form a judgement.,,,,,http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3419,Psychiatry,Psychiatric disorders|Mental health,"Topic concerning the branch of medicine that deals with the mangement of mental illness, emotional disturbance and abnormal behaviour.",false,,,http://edamontology.org/topic_3303,1.4,,,,,,,,,edamontology:topic_3419,,,,,,,,,,,,,,,,,,,,,,,,,,Mental health,,"Topic concerning the branch of medicine that deals with the mangement of mental illness, emotional disturbance and abnormal behaviour.",,Psychiatric disorders,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0220,Data processing and validation,Data types|Datatypes|File handling|Data file handling|Report processing|Report handling,"This includes editing, reformatting, conversion, transformation, validation, debugging, indexing and so on.|Topic concerning basic manipulations of files or reports of generic biological data.",false,,,http://edamontology.org/topic_3071,beta12orEarlier,,,,,,,,,edamontology:topic_0220,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning basic manipulations of files or reports of generic biological data.,File handling|Data file handling|Report processing|Report handling,Data types|Datatypes,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0654,DNA,DNA analysis,"The DNA sequences might be coding or non-coding sequences.|Topic concerning DNA sequences and structure, including processes such as methylation and replication.",false,,,http://edamontology.org/topic_0077,beta12orEarlier,,,,,,,,,edamontology:topic_0654,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning DNA sequences and structure, including processes such as methylation and replication.",DNA analysis,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3379,Preclinical and clinical studies,Preclinical studies|Clinical studies,"Topic concerning the testing of new medicines, vaccines or procedures on animals (preclinical) and humans (clinical) prior to their approval by regulatory authorities.",false,,,http://edamontology.org/topic_3376,1.4,,,,,,,,,edamontology:topic_3379,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the testing of new medicines, vaccines or procedures on animals (preclinical) and humans (clinical) prior to their approval by regulatory authorities.",,Preclinical studies|Clinical studies,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0172,Protein structure prediction,,"Topic concerning the prediction, modelling, recognition or design of protein secondary or tertiary structure or other structural features.",false,,,http://edamontology.org/topic_0082|http://edamontology.org/topic_2814,beta12orEarlier,,,,,,,,,edamontology:topic_0172,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Protein Structure Prediction,"Topic concerning the prediction, modelling, recognition or design of protein secondary or tertiary structure or other structural features.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3325,Rare diseases,,Topic concerning the study of rare diseases.,false,,,http://edamontology.org/topic_0634,1.3,,,,,,,,,edamontology:topic_3325,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the study of rare diseases.,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0820,Membrane and  lipoproteins,Membrane proteins|Lipoproteins|Transmembrane proteins,"Topic concerning lipoproteins (protein-lipid assemblies), and proteins or region of a protein that spans or are associated with a membrane.",false,,,http://edamontology.org/topic_0724,beta12orEarlier,,,,,,,,,edamontology:topic_0820,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning lipoproteins (protein-lipid assemblies), and proteins or region of a protein that spans or are associated with a membrane.",,Membrane proteins|Lipoproteins|Transmembrane proteins,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0183,Structure alignment,Structure alignment generation,"This includes the generation, storage, analysis, rendering etc. of structure alignments.|Topic concerning the superimposition of molecular tertiary structures or structural (3D) profiles (representing a structure or structure alignment).",false,,,http://edamontology.org/topic_1770,beta12orEarlier,,,,,,,,,edamontology:topic_0183,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the superimposition of molecular tertiary structures or structural (3D) profiles (representing a structure or structure alignment).,Structure alignment generation,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0130,"Protein folding, stability and design",Protein residue interactions|Protein design|Protein folding|Protein stability|Rational protein design,"Topic concerning protein stability, folding (in 3D space) and protein sequence-structure-function relationships.  This includes for example study of inter-atomic or inter-residue interactions in protein (3D) structures, the effect of mutation, and the design of proteins with specific properties, typically by designing changes (via site-directed mutagenesis) to an existing protein.",false,,,http://edamontology.org/topic_2814,beta12orEarlier,,,,,,,,,edamontology:topic_0130,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning protein stability, folding (in 3D space) and protein sequence-structure-function relationships.  This includes for example study of inter-atomic or inter-residue interactions in protein (3D) structures, the effect of mutation, and the design of proteins with specific properties, typically by designing changes (via site-directed mutagenesis) to an existing protein.",,Protein residue interactions|Protein design|Protein folding|Protein stability|Rational protein design,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0694,Protein secondary structure,Protein secondary structure analysis,"This includes assignment, analysis, comparison, prediction, rendering etc. of secondary structure data.|Topic concerning protein secondary structure or secondary structure alignments.",false,,,http://edamontology.org/topic_2814,beta12orEarlier,,,,,,,,,edamontology:topic_0694,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Protein Secondary Structure,Topic concerning protein secondary structure or secondary structure alignments.,Protein secondary structure analysis,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3412,Hepatic and biliary medicine,Liver disorders|Hepatobiliary medicine,"Topic concerning the branch of medicine that deals with the liver, gallbladder, bile ducts and bile.",false,,,http://edamontology.org/topic_3303,1.4,,,,,,,,,edamontology:topic_3412,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the branch of medicine that deals with the liver, gallbladder, bile ducts and bile.",Hepatobiliary medicine,Liver disorders,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0176,Molecular dynamics,Molecular motions|Molecular flexibility,This includes resources concerning flexibility and motion in protein and other molecular structures.|Topic concerning the simulation of molecular (typically protein) conformation using a computational model of physical forces and computer simulation.,false,,,http://edamontology.org/topic_0082,beta12orEarlier,,,,,,,,,edamontology:topic_0176,,,,,,,,,,,,,,,,,,topic,,,,,,,,Molecular motions|Molecular flexibility,,Topic concerning the simulation of molecular (typically protein) conformation using a computational model of physical forces and computer simulation.,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3398,Bioengineering,Diagnostic markers,Topic concerning the application of biological concepts and methods to the analytical and synthetic methodologies of engineering.,false,,,http://edamontology.org/topic_3297,1.4,,,,,,,,,edamontology:topic_3398,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the application of biological concepts and methods to the analytical and synthetic methodologies of engineering.,Diagnostic markers,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3397,Veterinary medicine,,,false,,,http://edamontology.org/topic_3303,1.4,,,,,,,,,edamontology:topic_3397,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the branch of medicine that deals with the prevention, diagnosis, and treatment of disease, disorder and injury in animals.",,,,,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3437,Leadership skills,,Topic concerning the ability to organise or influence a group of people to achieve a common goal.,false,,,http://edamontology.org/topic_3364,1.4,,,,,,,,,edamontology:topic_3437,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the ability to organise or influence a group of people to achieve a common goal.,,,,,http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0602,"Molecular interactions, pathways and networks",Network or pathway analysis|Molecular interactions|Biological networks|Biological pathways|Biological models,"Topic concerning molecular interactions, biological pathways, networks and other models.",false,,,http://edamontology.org/topic_2259,beta13,,,,,,,,,edamontology:topic_0602,,,,,,,,,,,,,,,,,,topic,,,,,,,http://edamontology.org/topic_3076,,BioCatalogue:Pathways|BioCatalogue:Pathway Retrieval,"Topic concerning molecular interactions, biological pathways, networks and other models.",,Network or pathway analysis|Molecular interactions|Biological networks|Biological pathways|Biological models,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_2229,Cell biology,,"Topic concerning cells, such as key genes and proteins involved in the cell cycle.",false,,,http://edamontology.org/topic_3070,beta12orEarlier,,,,,,,,,edamontology:topic_2229,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning cells, such as key genes and proteins involved in the cell cycle.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_2840,Toxicology,Computational toxicology|Toxicoinformatics|Toxicology,Topic concerning toxins and the adverse effects of these chemical substances on living organisms.,false,,,http://edamontology.org/topic_3377,beta12orEarlier,,,,,,,,,edamontology:topic_2840,,,,,,,,,,,,,,,,,,topic,,,,,,,,Toxicology,,Topic concerning toxins and the adverse effects of these chemical substances on living organisms.,,Computational toxicology|Toxicoinformatics,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3431,Technical writing,,"Topic concerning the process of creating any form of written technical communication including user manuals, technical manuals, help guides, standard operating procedures and work instructions.",false,,,http://edamontology.org/topic_3436,1.4,,,,,,,,,edamontology:topic_3431,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the process of creating any form of written technical communication including user manuals, technical manuals, help guides, standard operating procedures and work instructions.",,,,,http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_1811,Prokaryotes and archae,,"The resource may be specific to a prokaryote, a group of prokaryotes or all prokaryotes.|Topic concerning specific bacteria or archaea, e.g. information on a specific prokaryote genome including molecular sequences, genes and annotation.",false,,,http://edamontology.org/topic_0621,beta12orEarlier,,,,,,,,,edamontology:topic_1811,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning specific bacteria or archaea, e.g. information on a specific prokaryote genome including molecular sequences, genes and annotation.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3364,Auxiliary skills,Key competencies|Transferable skills|Employability skills,This entire branch will probably be hived off into it's own module.  Kept here for now as a convenience for annotators.|Topic concerning the transferable skills needed by an individual to make them 'employable' in addition to good technical understanding and subject knowledge.,false,,,http://www.w3.org/2002/07/owl#Thing,1.4,,,,,,,,,edamontology:topic_3364,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the transferable skills needed by an individual to make them 'employable' in addition to good technical understanding and subject knowledge.,Key competencies|Transferable skills|Employability skills,,,,http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3424,Business skills,Interpersonal skills,"Topic concerning the skills used by a person to properly interact with others.  In the business domain, the term generally refers to an employee's ability to get along with others while getting the job done.",false,,,http://edamontology.org/topic_3364,1.4,,,,,,,,,edamontology:topic_3424,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the skills used by a person to properly interact with others.  In the business domain, the term generally refers to an employee's ability to get along with others while getting the job done.",,Interpersonal skills,,,http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3371,Synthetic chemistry,Synthetic organic chemistry,Topic concerning the use of chemistry to create new compounds.,false,,,http://edamontology.org/topic_3314,1.4,,,,,,,,,edamontology:topic_3371,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the use of chemistry to create new compounds.,Synthetic organic chemistry,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0152,Carbohydrates,,"Topic concerning carbohydrates, typically including structural information.",false,,,http://edamontology.org/topic_3292,beta12orEarlier,,,,,,,,,edamontology:topic_0152,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning carbohydrates, typically including structural information.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3322,Respiratory medicine,Pulmonary disorders|Respiratory disease|Pulmonary medicine|Pulmonology,Topic concerning the study of respiratory system.,false,,,http://edamontology.org/topic_3303,1.3,,,,,,,,,edamontology:topic_3322,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the study of respiratory system.,Pulmonary medicine|Pulmonology,Pulmonary disorders|Respiratory disease,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0182,Sequence alignment,http://purl.bioontology.org/ontology/MSH/D016415,"This includes the generation of alignments (the identification of equivalent sites), the analysis of alignments, editing, visualisation, alignment databases, the alignment (equivalence between sites) of sequence profiles (representing sequence alignments) and so on.|Topic concerning the alignment of molecular sequences or sequence profiles (representing sequence alignments).",false,,,http://edamontology.org/topic_0159,beta12orEarlier,,,,,,,,,edamontology:topic_0182,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Protein Multiple Alignment|BioCatalogue:Protein Pairwise Alignment|BioCatalogue:Nucleotide Multiple Alignment|BioCatalogue:Nucleotide Pairwise Alignment|BioCatalogue:Protein Sequence Alignment|BioCatalogue:Nucleotide Sequence Alignment,Topic concerning the alignment of molecular sequences or sequence profiles (representing sequence alignments).,http://purl.bioontology.org/ontology/MSH/D016415,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3409,Gastroenterology,Gastrointestinal disorders,"Topic concerning the branch of medicine that deals with disorders of the oesophagus, stomach, duodenum, jejenum, ileum, large intestine, sigmoid colon and rectum.",false,,,http://edamontology.org/topic_3303,1.4,,,,,,,,,edamontology:topic_3409,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the branch of medicine that deals with disorders of the oesophagus, stomach, duodenum, jejenum, ileum, large intestine, sigmoid colon and rectum.",,Gastrointestinal disorders,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_2275,Molecular modelling,Homology modeling|Homology modelling|Comparative modelling|Comparative modeling|Molecular modeling,"Topic concerning the construction, analysis, evaluation, refinement etc. of models of a molecules properties or behaviour.",false,,,http://edamontology.org/topic_0082,beta12orEarlier,,,,,,,,,edamontology:topic_2275,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the construction, analysis, evaluation, refinement etc. of models of a molecules properties or behaviour.",Molecular modeling,Homology modeling|Homology modelling|Comparative modelling|Comparative modeling,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3301,Microbiology,,Topic concerning the biology of microorganisms.,false,,,http://edamontology.org/topic_3344,1.3,,,,,,,,,edamontology:topic_3301,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the biology of microorganisms.,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3346,Sequence search,Sequence database search,Topic concerning the search and retrieval from a database on the basis of molecular sequence similarity.,false,,,http://edamontology.org/topic_0159,1.3,,,,,,,,,edamontology:topic_3346,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the search and retrieval from a database on the basis of molecular sequence similarity.,Sequence database search,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3393,Quality affairs,Good clinical practice|Good manufacturing practice|Good laboratory practice|Quality assurance,Topic concerning the processes that need to be in place to ensure the quality of products for human or animal use.,false,,,http://edamontology.org/topic_3376,1.4,,,,,,,,,edamontology:topic_3393,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the processes that need to be in place to ensure the quality of products for human or animal use.,Quality assurance,Good clinical practice|Good manufacturing practice|Good laboratory practice,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0632,Sequence design,Primer design|in silico cloning|Gene design|Probe design|Primers|Probes|http://purl.bioontology.org/ontology/MSH/D015335,This includes the design of primers for PCR and DNA amplification or the design of molecular probes.|Topic concerning molecular probes (e.g. a peptide probe or DNA microarray probe) or primers (e.g. for PCR).,false,,,http://edamontology.org/topic_0080,beta12orEarlier,,,,,,,,,edamontology:topic_0632,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning molecular probes (e.g. a peptide probe or DNA microarray probe) or primers (e.g. for PCR).,,Primer design|in silico cloning|Gene design|Probe design|Primers|Probes,http://purl.bioontology.org/ontology/MSH/D015335,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3335,Cardiology,Heart disease|Cardiovascular disease|Cardiovascular medicine,Topic concerning the diseases and abnormalities of the heart and circulatory system.,false,,,http://edamontology.org/topic_3303,1.3,,,,,,,,,edamontology:topic_3335,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the diseases and abnormalities of the heart and circulatory system.,Cardiovascular medicine,Heart disease|Cardiovascular disease,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3174,Metagenomics,Environmental genomics|Community genomics|Ecogenomics|http://purl.bioontology.org/ontology/MSH/D056186,"Topic concerning the study of genetic material recovered from environmental samples, and associated environmental data.",false,,,http://edamontology.org/topic_0622|http://edamontology.org/topic_0610,1.1,,,,,,,,,edamontology:topic_3174,,,,,,,,,,,,,,,,,,topic,,,,,,,,Environmental genomics|Community genomics|Ecogenomics,,"Topic concerning the study of genetic material recovered from environmental samples, and associated environmental data.",http://purl.bioontology.org/ontology/MSH/D056186,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3434,Scientific English,,"Topic concerning the use of English to communicate scientific concepts and results in a clear, unambiguous way appropriate to a scientific audience.",false,,,http://edamontology.org/topic_3436,1.4,,,,,,,,,edamontology:topic_3434,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the use of English to communicate scientific concepts and results in a clear, unambiguous way appropriate to a scientific audience.",,,,,http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3441,Patient engagement,Patient representation|Patient advocacy,"Topic concerning the engagement of patients in research, development and policy.",false,,,http://edamontology.org/topic_3439,1.4,,,,,,,,,edamontology:topic_3441,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the engagement of patients in research, development and policy.",,Patient representation|Patient advocacy,,,http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_2259,Systems biology,Biological system modelling|Biological modelling|Biological models|http://en.wikipedia.org/wiki/Systems_biology|http://purl.bioontology.org/ontology/MSH/D049490,This includes databases of models and methods to construct or analyse a model.|Topic concerning the holistic modelling and analysis of complex biological systems and the interactions therein.,false,,,http://edamontology.org/topic_3070,beta12orEarlier,,,,,,,,,edamontology:topic_2259,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Systems Biology|BioCatalogue:Model Analysis|BioCatalogue:Model Execution|BioCatalogue:Model Creation,Topic concerning the holistic modelling and analysis of complex biological systems and the interactions therein.,http://en.wikipedia.org/wiki/Systems_biology|http://purl.bioontology.org/ontology/MSH/D049490,Biological system modelling|Biological modelling|Biological models,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0202,Pharmacology,Computational pharmacology|Pharmacoinformatics,Topic concerning the study of drugs and their effects or responses in living systems. ,false,,,http://edamontology.org/topic_3344,beta12orEarlier,,,,,,,,,edamontology:topic_0202,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the study of drugs and their effects or responses in living systems. ,,Computational pharmacology|Pharmacoinformatics,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_2830,"Immunoproteins, genes and antigens",Immunogenes|Immunoproteins|Immunopeptides|Antigens,"This includes T cell receptors (TR), major histocompatibility complex (MHC), immunoglobulin superfamily (IgSF) / antibodies, major histocompatibility complex superfamily (MhcSF), etc.""|Topic concerning immunity-related genes, proteins and their ligands.",false,,,http://edamontology.org/topic_0724|http://edamontology.org/topic_0804,beta12orEarlier,,,,,,,,,edamontology:topic_2830,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning immunity-related genes, proteins and their ligands.",,Immunogenes|Immunoproteins|Immunopeptides|Antigens,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0797,Comparative genomics,,"Topic concerning the study (typically comparison) of the sequence, structure or function of multiple genomes.",false,,,http://edamontology.org/topic_0622,beta12orEarlier,,,,,,,,,edamontology:topic_0797,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Comparative Genomics,"Topic concerning the study (typically comparison) of the sequence, structure or function of multiple genomes.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3380,Intellectual property,Copyrights|Patents|Intellectual property rights|IP|IPR,"Topic concerning intangible property that is the result of creativity, such as patents and copyrights.",false,,,http://edamontology.org/topic_3364,1.4,,,,,,,,,edamontology:topic_3380,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning intangible property that is the result of creativity, such as patents and copyrights.",Intellectual property rights|IP|IPR,Copyrights|Patents,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0081,Structure analysis,Computational structural biology|Structure data resources|Structure databases|http://purl.bioontology.org/ontology/MSH/D015394|Structure analysis|Structural bioinformatics,"This includes related concepts such as structural properties, alignments and structural motifs.|Topic concerning the curation, processing and analysis of the structure of biological molecules, typically proteins and nucleic acids and other macromolecules.",false,,,http://edamontology.org/topic_3307,beta12orEarlier,,,,,,,,,edamontology:topic_0081,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the curation, processing and analysis of the structure of biological molecules, typically proteins and nucleic acids and other macromolecules.",Structure analysis|Structural bioinformatics,Computational structural biology|Structure data resources|Structure databases,http://purl.bioontology.org/ontology/MSH/D015394,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0783,Pathogens,,"The resource may be specific to a pathogen, a group of pathogens or all pathogens.|Topic concerning pathogens, e.g. information on a specific vertebrate genome including molecular sequences, genes and annotation.",false,,,http://edamontology.org/topic_0621,beta12orEarlier,,,,,,,,,edamontology:topic_0783,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning pathogens, e.g. information on a specific vertebrate genome including molecular sequences, genes and annotation.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0077,Nucleic acids,http://purl.bioontology.org/ontology/MSH/D017422|http://purl.bioontology.org/ontology/MSH/D017423|Nucleic acid physicochemistry|Nucleic acid properties|Nucleic acid bioinformatics|Nucleic acid informatics|Nucleic acid analysis,"Topic concerning the processing and analysis of nucleic acid sequence, structural and other data.",false,,,http://edamontology.org/topic_3292,beta12orEarlier,,,,,,,,,edamontology:topic_0077,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the processing and analysis of nucleic acid sequence, structural and other data.",Nucleic acid bioinformatics|Nucleic acid informatics|Nucleic acid analysis,http://purl.bioontology.org/ontology/MSH/D017422|http://purl.bioontology.org/ontology/MSH/D017423|Nucleic acid physicochemistry|Nucleic acid properties,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3405,Dentistry,,"Topic concerning the study, diagnosis, prevention and treatments of disorders of the oral cavity, maxillofacial area and adjacent structures.",false,,,http://edamontology.org/topic_3303,1.4,,,,,,,,,edamontology:topic_3405,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the study, diagnosis, prevention and treatments of disorders of the oral cavity, maxillofacial area and adjacent structures.",,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0082,Structure prediction,,Topic concerning the prediction of molecular (secondary or tertiary) structure.,false,,,http://edamontology.org/topic_0081,beta12orEarlier,,,,,,,,,edamontology:topic_0082,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the prediction of molecular (secondary or tertiary) structure.,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3334,Neurology,Neurological disorders,"Topic concerning the branch of medicine that deals with the anatomy, functions and disorders of the nervous system.",false,,,http://edamontology.org/topic_3303,1.3,,,,,,,,,edamontology:topic_3334,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the branch of medicine that deals with the anatomy, functions and disorders of the nervous system.",,Neurological disorders,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3369,Chemical biology,,Topic concerning the use of synthetic chemistry to study and manipulate biological systems.,false,,,http://edamontology.org/topic_3371|http://edamontology.org/topic_3070,1.4,,,,,,,,,edamontology:topic_3369,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the use of synthetic chemistry to study and manipulate biological systems.,,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3415,Medical toxicology,,"Topic concerning the branch of medicine that deals with the diagnosis, management and prevention of poisoning and other adverse health effects caused by medications, occupational and environmental toxins, and biological agents.",false,,,http://edamontology.org/topic_3303,1.4,,,,,,,,,edamontology:topic_3415,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the branch of medicine that deals with the diagnosis, management and prevention of poisoning and other adverse health effects caused by medications, occupational and environmental toxins, and biological agents.",,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3308,Transcriptomics,Transcriptome,"Topic concerning the analysis of transcriptomes, or a set of all the RNA molecules in a specific cell, tissue etc.",false,,,http://edamontology.org/topic_0622|http://edamontology.org/topic_0203,1.3,,,,,,,,,edamontology:topic_3308,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the analysis of transcriptomes, or a set of all the RNA molecules in a specific cell, tissue etc.",,Transcriptome,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3361,Laboratory techniques,Lab techniques,Topic concerning the procedures used to conduct an experiment.,false,,,http://www.w3.org/2002/07/owl#Thing,1.4,,,,,,,,,edamontology:topic_3361,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the procedures used to conduct an experiment.,Lab techniques,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0108,Protein expression,Translation,Topic concerning the translation of mRNA into protein and subsequent protein processing in the cell.,false,,,http://edamontology.org/topic_0078,beta12orEarlier,,,,,,,,,edamontology:topic_0108,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the translation of mRNA into protein and subsequent protein processing in the cell.,,Translation,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3362,Technology,,Topic concerning the application of scientific knowledge for practical purposes.,false,,,http://www.w3.org/2002/07/owl#Thing,1.4,,,,,,,,,edamontology:topic_3362,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the application of scientific knowledge for practical purposes.,,,,,http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0622,Genomics,http://purl.bioontology.org/ontology/MSH/D023281,"Topic concerning whole genomes of one or more organisms, or genomes in general, such as meta-information on genomes, genome projects, gene names etc.",false,,,http://edamontology.org/topic_3391,beta12orEarlier,,,,,,,,,edamontology:topic_0622,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Genomics,"Topic concerning whole genomes of one or more organisms, or genomes in general, such as meta-information on genomes, genome projects, gene names etc.",http://purl.bioontology.org/ontology/MSH/D023281,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0821,Enzymes,Enzymology,"Topic concerning proteins that catalyze chemical reaction, the kinetics of enzyme-catalysed reactions, enzyme nomenclature etc.",false,,,http://edamontology.org/topic_0724,beta12orEarlier,,,,,,,,,edamontology:topic_0821,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning proteins that catalyze chemical reaction, the kinetics of enzyme-catalysed reactions, enzyme nomenclature etc.",Enzymology,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0634,Pathology,Diseases,"Topic concerning diseases, including diseases in general and the genes, gene variations and proteins involved in one or more specific diseases.",false,,,http://edamontology.org/topic_3303,beta12orEarlier,,,,,,,,,edamontology:topic_0634,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning diseases, including diseases in general and the genes, gene variations and proteins involved in one or more specific diseases.",Diseases,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3320,RNA splicing,,"This includes the study of splice sites, splicing patterns, splice alternatives or variants, isoforms, etc.|Topic concerning RNA splicing; post-transcription RNA modification involving the removal of introns and joining of exons.",false,,,http://edamontology.org/topic_0099|http://edamontology.org/topic_3321,1.3,,,,,,,,,edamontology:topic_3320,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning RNA splicing; post-transcription RNA modification involving the removal of introns and joining of exons.,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3307,Computational biology,Theoretical biology|Mathematical biology|Biomathematics,"This includes the modeling and treatment of biological processes and systems in mathematical terms (theoretical biology).|Topic concerning the development and application of theory, analytical methods, mathematical models and computational simulation of biological systems.",false,,,http://edamontology.org/topic_3316|http://edamontology.org/topic_3070,1.3,,,,,,,,,edamontology:topic_3307,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Model Execution,"Topic concerning the development and application of theory, analytical methods, mathematical models and computational simulation of biological systems.",,Theoretical biology|Mathematical biology|Biomathematics,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0625,Genotype and phenotype,Genotype and phenotype resources|Genotyping,"Topic concerning the study of genetic constitution of a living entity, such as an individual, and organism, a cell and so on, typically with respect to a particular observable phenotypic traits, or resources concerning such traits, which might be an aspect of biochemistry, physiology, morphology, anatomy, development and so on.",false,,,http://edamontology.org/topic_3053,beta12orEarlier,,,,,,,,,edamontology:topic_0625,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the study of genetic constitution of a living entity, such as an individual, and organism, a cell and so on, typically with respect to a particular observable phenotypic traits, or resources concerning such traits, which might be an aspect of biochemistry, physiology, morphology, anatomy, development and so on.",Genotype and phenotype resources|Genotyping,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3360,Biomarkers,Diagnostic markers,"Topic concerning objective indicators of biological state often used to assess health, and determinate treatment.",false,,,http://edamontology.org/topic_3070,1.4,,,,,,,,,edamontology:topic_3360,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning objective indicators of biological state often used to assess health, and determinate treatment.",Diagnostic markers,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0091,Bioinformatics,http://purl.bioontology.org/ontology/MSH/D016247,"This includes data  processing in general, including basic handling of files and databases, datatypes, workflows and annotation.|Topic concerning the archival, curation, processing and analysis of complex biological data.",false,,,http://edamontology.org/topic_3316|http://edamontology.org/topic_3070,beta12orEarlier,,,,,,,,,edamontology:topic_0091,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the archival, curation, processing and analysis of complex biological data.",,http://purl.bioontology.org/ontology/MSH/D016247,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3341,Clone library,,"Topic concerning collections of DNA, including both collections of cloned molecules, and populations of micro-organisms that store and propagate cloned DNA.",false,,,http://edamontology.org/topic_3277,1.3,,,,,,,,,edamontology:topic_3341,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning collections of DNA, including both collections of cloned molecules, and populations of micro-organisms that store and propagate cloned DNA.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0798,Mobile genetic elements,,"Topic concerning mobile genetic elements, such as transposons, Plasmids, Bacteriophage elements and Group II introns.",false,,,http://edamontology.org/topic_0654,beta12orEarlier,,,,,,,,,edamontology:topic_0798,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning mobile genetic elements, such as transposons, Plasmids, Bacteriophage elements and Group II introns.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3420,Reproductive health,Family planning|Reproductive disorders|Fertility medicine|Audiovestibular medicine,"Topic concerning the health of the reproductive processes, functions and systems at all stages of life.",false,,,http://edamontology.org/topic_3303,1.4,,,,,,,,,edamontology:topic_3420,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the health of the reproductive processes, functions and systems at all stages of life.",Audiovestibular medicine,Family planning|Reproductive disorders|Fertility medicine,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3387,Marine biology,,Topic concerning the study of organisms in the ocean or brackish waters.,false,,,http://edamontology.org/topic_3070,1.4,,,,,,,,,edamontology:topic_3387,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the study of organisms in the ocean or brackish waters.,,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3300,Physiology,,Topic concerning the functions of living organisms and their constituent parts.,false,,,http://edamontology.org/topic_3303,1.3,,,,,,,,,edamontology:topic_3300,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the functions of living organisms and their constituent parts.,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3430,Scientific writing,,Topic concerning process of writing scientic reports for publication in peer reviewed journals.,false,,,http://edamontology.org/topic_3436,1.4,,,,,,,,,edamontology:topic_3430,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning process of writing scientic reports for publication in peer reviewed journals.,,,,,http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3433,Project management,,"Topic concerning the application of processes, methods, knowledge, skills and experience to achieve project objectives on time and to budget.",false,,,http://edamontology.org/topic_3364,1.4,,,,,,,,,edamontology:topic_3433,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the application of processes, methods, knowledge, skills and experience to achieve project objectives on time and to budget.",,,,,http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0173,Nucleic acid structure prediction,Nucleic acid design|DNA structure prediction|Nucleic acid folding|RNA structure prediction,Topic concerning the folding of nucleic acid molecules and the prediction or design of nucleic acid (typically RNA) sequences with specific conformations.,false,,,http://edamontology.org/topic_0082|http://edamontology.org/topic_0097,beta12orEarlier,,,,,,,,,edamontology:topic_0173,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Nucleotide Tertiary Structure|BioCatalogue:Nucleotide Structure Prediction|BioCatalogue:Nucleotide Secondary Structure,Topic concerning the folding of nucleic acid molecules and the prediction or design of nucleic acid (typically RNA) sequences with specific conformations.,RNA structure prediction,Nucleic acid design|DNA structure prediction|Nucleic acid folding,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0102,Mapping,Linkage mapping|Genetic linkage|Linkage,"This includes resources that aim to identify, map or analyse genetic markers in DNA sequences, for example to produce a genetic (linkage) map of a chromosome or genome or to analyse genetic linkage and synteny. It also includes resources for physical (sequence) maps of a DNA sequence showing the physical distance (base pairs) between features or landmarks such as restriction sites, cloned DNA fragments, genes and other genetic markers.|Topic concerning the mapping of complete (typically nucleotide) sequences.",false,,,http://edamontology.org/topic_0640,beta12orEarlier,,,,,,,,,edamontology:topic_0102,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the mapping of complete (typically nucleotide) sequences.,,Linkage mapping|Genetic linkage|Linkage,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0180,Protein fold recognition,,"For example threading, or the alignment of molecular sequences to structures, structural (3D) profiles or templates (representing a structure or structure alignment).|Topic concerning the recognition (prediction and assignment) of known protein structural domains or folds in protein sequence(s).",false,,,http://edamontology.org/topic_0082,beta12orEarlier,,,,,,,,,edamontology:topic_0180,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the recognition (prediction and assignment) of known protein structural domains or folds in protein sequence(s).,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3413,Infectious tropical disease,,Topic concerning the branch of medicine that deals with the infectious diseases of the tropics. ,false,,,http://edamontology.org/topic_3324,1.4,,,,,,,,,edamontology:topic_3413,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the branch of medicine that deals with the infectious diseases of the tropics. ,,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3411,Gynaecology and obstetrics,Gynaecology|Gynaecological disorders|Obstetrics,"Topic concerning the branch of medicine that deals with the health of the female reproductive system, pregnancy and birth.",false,,,http://edamontology.org/topic_3303,1.4,,,,,,,,,edamontology:topic_3411,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the branch of medicine that deals with the health of the female reproductive system, pregnancy and birth.",,Gynaecology|Gynaecological disorders|Obstetrics,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3408,Haematology,Blood disorders|Haematological disorders,"Topic concerning the branch of medicine that deals with the blood, blood-forming organs and blood diseases.",false,,,http://edamontology.org/topic_3303,1.4,,,,,,,,,edamontology:topic_3408,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the branch of medicine that deals with the blood, blood-forming organs and blood diseases.",,Blood disorders|Haematological disorders,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0157,"Sequence composition, complexity and repeats",Repeat sequences|Low complexity sequences|Sequence composition|Sequence complexity|Sequence repeats,"Topic concerning the archival, processing and analysis of the basic character composition of molecular sequences, for example character or word frequency, ambiguity, complexity, particularly regions of low complexity, and repeats or the repetitive nature of molecular sequences.",false,,,http://edamontology.org/topic_0080,beta12orEarlier,,,,,,,,,edamontology:topic_0157,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Repeats,"Topic concerning the archival, processing and analysis of the basic character composition of molecular sequences, for example character or word frequency, ambiguity, complexity, particularly regions of low complexity, and repeats or the repetitive nature of molecular sequences.",,Repeat sequences|Low complexity sequences|Sequence composition|Sequence complexity|Sequence repeats,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3429,Medical writing,,"Topic concerning the process of creating clear and acurate documentation to describe research results, product use, and other medical information.",false,,,http://edamontology.org/topic_3436,1.4,,,,,,,,,edamontology:topic_3429,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the process of creating clear and acurate documentation to describe research results, product use, and other medical information.",,,,,http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0123,Protein properties,Protein hydropathy|Protein physicochemistry,"Topic concerning the study of the physical and biochemical properties of peptides and proteins, for example the hydrophobic, hydrophilic and charge properties of a protein.",false,,,http://edamontology.org/topic_0078,beta12orEarlier,,,,,,,,,edamontology:topic_0123,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the study of the physical and biochemical properties of peptides and proteins, for example the hydrophobic, hydrophilic and charge properties of a protein.",Protein physicochemistry,Protein hydropathy,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0089,Ontology and terminology,http://purl.bioontology.org/ontology/MSH/D002965|Terminology|Applied ontology|Ontologies|Ontology,"Topic concerning the conceptualisation, categorisation and nomenclature (naming) of entities or phenomena within biology or bioinformatics. This includes formal ontologies, controlled vocabularies, structured glossary, symbols and terminology or other related resource.",false,,,http://www.w3.org/2002/07/owl#Thing,beta12orEarlier,,,,,,,,,edamontology:topic_0089,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Ontology|BioCatalogue:Ontology Lookup,"Topic concerning the conceptualisation, categorisation and nomenclature (naming) of entities or phenomena within biology or bioinformatics. This includes formal ontologies, controlled vocabularies, structured glossary, symbols and terminology or other related resource.",,http://purl.bioontology.org/ontology/MSH/D002965|Terminology|Applied ontology|Ontologies|Ontology,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0623,Gene families,"Gene and protein families|Gene family|Genes, gene family or system|Gene system","Topic concerning particular gene(s), gene family or other gene group or system and their encoded proteins.",false,,,http://edamontology.org/topic_3053|http://edamontology.org/topic_0594,beta12orEarlier,,,,,,,,,edamontology:topic_0623,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning particular gene(s), gene family or other gene group or system and their encoded proteins.","Gene and protein families|Gene family|Genes, gene family or system|Gene system",,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_1770,Structure comparison,,This might involve comparison of secondary or tertiary (3D) structural information.|Topic concerning the comparison of two or more molecular structures.,false,,,http://edamontology.org/topic_0081,beta12orEarlier,,,,,,,,,edamontology:topic_1770,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the comparison of two or more molecular structures.,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_2819,Invertebrates,,"The resource may be specific to an invertebrate, a group of invertebrates or all invertebrates.|Topic concerning invertebrates, e.g. information on a specific invertebrate genome including molecular sequences, genes and annotation.",false,,,http://edamontology.org/topic_2818,beta12orEarlier,,,,,,,,,edamontology:topic_2819,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning invertebrates, e.g. information on a specific invertebrate genome including molecular sequences, genes and annotation.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0640,Nucleic acid sequence analysis,,"Topic concerning the archival, processing and analysis of nucleotide sequences and and sequence-based entities such as alignments, motifs and profiles.",false,,,http://edamontology.org/topic_0080,beta12orEarlier,,,,,,,,,edamontology:topic_0640,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Nucleotide Sequence Analysis,"Topic concerning the archival, processing and analysis of nucleotide sequences and and sequence-based entities such as alignments, motifs and profiles.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0613,Peptides and amino acids,Amino acids|Peptides,"Topic concerning the physicochemical, biochemical or structural properties of amino acids or peptides.",false,,,http://edamontology.org/topic_0154,beta12orEarlier,,,,,,,,,edamontology:topic_0613,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the physicochemical, biochemical or structural properties of amino acids or peptides.",,Amino acids|Peptides,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0099,RNA,,Topic concerning RNA sequences and structures.,false,,,http://edamontology.org/topic_0077,beta12orEarlier,,,,,,,,,edamontology:topic_0099,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning RNA sequences and structures.,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3314,Chemistry,,"Topic concerning the composition and properties of matter, reactions, and the use of reactions to create new substances.",false,,,http://www.w3.org/2002/07/owl#Thing,1.3,,,,,,,,,edamontology:topic_3314,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the composition and properties of matter, reactions, and the use of reactions to create new substances.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3428,"Ethical, legal and social implications",ELSI,Topic concerning the impact of research on society.,false,,,http://edamontology.org/topic_3364,1.4,,,,,,,,,edamontology:topic_3428,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the impact of research on society.,ELSI,,,,http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3065,Embryology,,Topic concerning the development of organisms between the one-cell stage (typically the zygote) and the end of the embryonic stage.,false,,,http://edamontology.org/topic_3064,beta13,,,,,,,,,edamontology:topic_3065,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the development of organisms between the one-cell stage (typically the zygote) and the end of the embryonic stage.,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0639,Protein sequence analysis,Protein sequences,"Topic concerning archival, processing and analysis of protein sequences and sequence-based entities such as alignments, motifs and profiles.",false,,,http://edamontology.org/topic_0080,beta12orEarlier,,,,,,,,,edamontology:topic_0639,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Protein Sequence Analysis,"Topic concerning archival, processing and analysis of protein sequences and sequence-based entities such as alignments, motifs and profiles.",Protein sequences,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3321,Molecular genetics,,Topic concerning the structure and function of genes at a molecular level.,false,,,http://edamontology.org/topic_3053,1.3,,,,,,,,,edamontology:topic_3321,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the structure and function of genes at a molecular level.,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0153,Lipids,,Topic concerning lipids and their structures.,false,,,http://edamontology.org/topic_3292,beta12orEarlier,,,,,,,,,edamontology:topic_0153,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning lipids and their structures.,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3401,Pain medicine,Ageing|Algiatry,"Topic concerning with the prevention of pain and the evaluation, treatment and rehabilitation of persons in pain.",false,,,http://edamontology.org/topic_3303,1.4,,,,,,,,,edamontology:topic_3401,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning with the prevention of pain and the evaluation, treatment and rehabilitation of persons in pain.",Ageing|Algiatry,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0122,Structural genomics,,Topic concerning the elucidation of the three dimensional structure for all (available) proteins in a given organism.,false,,,http://edamontology.org/topic_0622|http://edamontology.org/topic_1317,beta12orEarlier,,,,,,,,,edamontology:topic_0122,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Structural Genomics,Topic concerning the elucidation of the three dimensional structure for all (available) proteins in a given organism.,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0219,Data curation and annotation,Ontology annotation|Genome annotation|Annotation|Curation,"Topic concerning the organisation and maintenance of a collection of biological database entries (or other such entities) and their annotation, typically with terms from a controlled vocabulary.",false,,,http://edamontology.org/topic_3071,beta12orEarlier,,,,,,,,,edamontology:topic_0219,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Ontology Annotation|BioCatalogue:Genome Annotation,"Topic concerning the organisation and maintenance of a collection of biological database entries (or other such entities) and their annotation, typically with terms from a controlled vocabulary.",,Ontology annotation|Genome annotation|Annotation|Curation,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3382,Imaging,Microscopy,Topic concerning the visual representation of an object.,false,,,http://edamontology.org/topic_3361,1.4,,,,,,,,,edamontology:topic_3382,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the visual representation of an object.,,Microscopy,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0121,Proteomics,Peptide identification|Protein and peptide identification|Protein expression|http://purl.bioontology.org/ontology/MSH/D040901,"Proteomics includes any methods (especially high-throughput) that separate, characterize and identify expressed proteins such as mass spectrometry, two-dimensional gel electrophoresis and protein microarrays, as well as in-silico methods that perform proteolytic or mass calculations on a protein sequence and other analyses of protein expression data, for example in different cells or tissues.|Topic concerning protein and peptide identification, especially in the study of whole proteomes of organisms.",false,,,http://edamontology.org/topic_3391,beta12orEarlier,,,,,,,,,edamontology:topic_0121,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Proteomics,"Topic concerning protein and peptide identification, especially in the study of whole proteomes of organisms.",http://purl.bioontology.org/ontology/MSH/D040901,Peptide identification|Protein and peptide identification|Protein expression,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3336,Drug discovery,,"This includes methods that search compound collections, generate or analyse drug 3D conformations, identify drug targets with structural docking etc.|Topic concerning the discovery and design of drugs or potential drug compounds.",false,,,http://edamontology.org/topic_3314|http://edamontology.org/topic_3376,1.3,,,,,,,,,edamontology:topic_3336,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the discovery and design of drugs or potential drug compounds.,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3338,Mouse clinic,,"Topic concerning laboratory study of mice, for example, phenotyping, and mutagenesis of mouse cell lines.",false,,,http://edamontology.org/topic_3277,1.3,,,,,,,,,edamontology:topic_3338,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning laboratory study of mice, for example, phenotyping, and mutagenesis of mouse cell lines.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3421,Surgery,,"Topic concerning the use of operative, manual and instrumental techniques on a patient to investigate and/or treat a pathological condition or help improve bodily function or appearance.",false,,,http://edamontology.org/topic_3303,1.4,,,,,,,,,edamontology:topic_3421,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the use of operative, manual and instrumental techniques on a patient to investigate and/or treat a pathological condition or help improve bodily function or appearance.",,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3056,Population genetics,,"Topic concerning the distribution of allele frequencies in a population of organisms and its change subject to evolutionary processes including natural selection, genetic drift, mutation and gene flow.",false,,,http://edamontology.org/topic_3053,beta13,,,,,,,,,edamontology:topic_3056,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the distribution of allele frequencies in a population of organisms and its change subject to evolutionary processes including natural selection, genetic drift, mutation and gene flow.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0080,Sequence analysis,Sequence databases|http://purl.bioontology.org/ontology/MSH/D017421|Sequences,"Topic concerning the archival, processing and analysis of molecular sequences (monomer composition of polymers) including molecular sequence data resources, sequence sites, alignments, motifs and profiles.",false,,,http://edamontology.org/topic_3307,beta12orEarlier,,,,,,,,,edamontology:topic_0080,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Sequence Analysis,"Topic concerning the archival, processing and analysis of molecular sequences (monomer composition of polymers) including molecular sequence data resources, sequence sites, alignments, motifs and profiles.",http://purl.bioontology.org/ontology/MSH/D017421|Sequences,Sequence databases,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3414,Trauma medicine,,"Topic concerning the branch of medicine that treats body wounds or shock produced by sudden physical injury, as from violence or accident.",false,,,http://edamontology.org/topic_3303,1.4,,,,,,,,,edamontology:topic_3414,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the branch of medicine that treats body wounds or shock produced by sudden physical injury, as from violence or accident.",,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0154,Small molecules,CHEBI:23367,"Small molecules include organic molecules, metal-organic compounds, small polypeptides, small polysaccharides and oligonucleotides.  Structural data is usually included.|Topic concerning small molecules of biological significance, typically archival, curation, processing and analysis of structural information.",false,,,http://edamontology.org/topic_3292,beta12orEarlier,,,,,,,,,edamontology:topic_0154,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning small molecules of biological significance, typically archival, curation, processing and analysis of structural information.",,,CHEBI:23367,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3410,Gender medicine,,Topic concerning the study of the biological and physiological differences between males and females and how they effect differences in disease presentation and management.,false,,,http://edamontology.org/topic_3303,1.4,,,,,,,,,edamontology:topic_3410,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the study of the biological and physiological differences between males and females and how they effect differences in disease presentation and management.,,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3324,Infectious disease,Communicable disease|Transmissable disease,"Topic concerning the branch of medicine that deals with the prevention, diagnosis and management of transmissable disease with clinically evident illness resulting from infection with pathogenic biological agents (viruses, bacteria, fungi, protozoa, parasites and prions).",false,,,http://edamontology.org/topic_0634,1.3,,,,,,,,,edamontology:topic_3324,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the branch of medicine that deals with the prevention, diagnosis and management of transmissable disease with clinically evident illness resulting from infection with pathogenic biological agents (viruses, bacteria, fungi, protozoa, parasites and prions).",Communicable disease|Transmissable disease,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3295,Epigenetics,"http://purl.bioontology.org/ontology/MSH/D019175|Histone modification|DNA methylation|Topic concerning the study of heritable changes, for example in gene expression or phenotype, caused by mechanisms other than changes in the DNA sequence.",This includes sub-topics such as histone modification and DNA methylation.,false,,,http://edamontology.org/topic_3321,1.3,,,,,,,,,edamontology:topic_3295,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,,,"http://purl.bioontology.org/ontology/MSH/D019175|Histone modification|DNA methylation|Topic concerning the study of heritable changes, for example in gene expression or phenotype, caused by mechanisms other than changes in the DNA sequence.",,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0601,Protein modifications,GO:0006464|MOD:00000|Protein post-translational modification,"EDAM does not describe all possible protein modifications. For fine-grained annotation of protein modification use the Gene Ontology (children of concept GO:0006464) and/or the Protein Modifications ontology (children of concept MOD:00000)|Topic concerning protein chemical modifications, e.g. post-translational modifications.",false,,,http://edamontology.org/topic_0108,beta12orEarlier,,,,,,,,,edamontology:topic_0601,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning protein chemical modifications, e.g. post-translational modifications.",Protein post-translational modification,,GO:0006464|MOD:00000,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3345,Data identity and mapping,Topic concerning the identity of biological data and the mapping of entities in different databases.,,false,,,http://edamontology.org/topic_3071,1.3,,,,,,,,,edamontology:topic_3345,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,,Topic concerning the identity of biological data and the mapping of entities in different databases.,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0174,Ab initio structure prediction,de novo protein structure prediction,"Topic concerning the prediction of three-dimensional structure of a (typically protein) sequence from first principles, using a physics-based or empirical scoring function and without using explicit structural templates.",false,,,http://edamontology.org/topic_0082,beta12orEarlier,,,,,,,,,edamontology:topic_0174,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the prediction of three-dimensional structure of a (typically protein) sequence from first principles, using a physics-based or empirical scoring function and without using explicit structural templates.",de novo protein structure prediction,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0698,Protein tertiary structure,Protein tertiary structure analysis,Topic concerning protein tertiary structures.,false,,,http://edamontology.org/topic_2814,beta12orEarlier,,,,,,,,,edamontology:topic_0698,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Protein Tertiary Structure,Topic concerning protein tertiary structures.,Protein tertiary structure analysis,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3391,Omics,,"Topic concerning the collective characterisation and quantification of pools of biological molecules that translate into the structure, function, and dynamics of an organism or organisms.",false,,,http://edamontology.org/topic_3070,1.4,,,,,,,,,edamontology:topic_3391,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the collective characterisation and quantification of pools of biological molecules that translate into the structure, function, and dynamics of an organism or organisms.",,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3396,Systems medicine,,"Topic concerning an interdisciplinary field of study that looks at the dynamic systems of the human body as part of an integrted whole, incoporating biochemical, physiological, and environmental interactions that sustain life.",false,,,http://edamontology.org/topic_3303,1.4,,,,,,,,,edamontology:topic_3396,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning an interdisciplinary field of study that looks at the dynamic systems of the human body as part of an integrted whole, incoporating biochemical, physiological, and environmental interactions that sustain life.",,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3403,Critical care medicine,Acute medicine|Emergency medicine|Geriatrics,"Topic concerning the multidisciplinary that cares for patients with acute, life-threatening illness or injury.",false,,,http://edamontology.org/topic_3335,1.4,,,,,,,,,edamontology:topic_3403,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the multidisciplinary that cares for patients with acute, life-threatening illness or injury.",Acute medicine|Emergency medicine|Geriatrics,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0624,Chromosomes,,Topic concerning chromosomes.,false,,,http://edamontology.org/topic_0654,beta12orEarlier,,,,,,,,,edamontology:topic_0624,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning chromosomes.,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0196,Sequence assembly,Assembly,This covers for example the alignment of sequences of (typically millions) of short reads to a reference genome.|Topic concerning the assembly of fragments of a DNA sequence to reconstruct the original sequence.,false,,,http://edamontology.org/topic_0640,beta12orEarlier,,,,,,,,,edamontology:topic_0196,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the assembly of fragments of a DNA sequence to reconstruct the original sequence.,,Assembly,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0736,Protein domains and folds,Protein folds|Protein domains,Topic concerning protein tertiary structural domains and folds.,false,,,http://edamontology.org/topic_2814,beta12orEarlier,,,,,,,,,edamontology:topic_0736,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Domains,Topic concerning protein tertiary structural domains and folds.,,Protein folds|Protein domains,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_2269,Statistics,Biostatistics|http://purl.bioontology.org/ontology/MSH/D056808|http://en.wikipedia.org/wiki/Biostatistics,Topic concerning the application of statistical methods to biological problems.,false,,,http://edamontology.org/topic_3315,beta12orEarlier,,,,,,,,,edamontology:topic_2269,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Biostatistics,Topic concerning the application of statistical methods to biological problems.,http://purl.bioontology.org/ontology/MSH/D056808|http://en.wikipedia.org/wiki/Biostatistics,Biostatistics,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3077,Data acquisition and deposition,Data acquisition|Data deposition|Deposition|Database submission,Topic concerning the acquisition and deposition of biological data.,false,,,http://edamontology.org/topic_3071,beta13,,,,,,,,,edamontology:topic_3077,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the acquisition and deposition of biological data.,Database submission,Data acquisition|Data deposition|Deposition,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3315,Mathematics,Maths,"Topic concerning the composition and properties of matter, reactions, and the use of reactions to create new substances.",false,,,http://www.w3.org/2002/07/owl#Thing,1.3,,,,,,,,,edamontology:topic_3315,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the composition and properties of matter, reactions, and the use of reactions to create new substances.",Maths,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0607,Laboratory information management,Laboratory resources,"Topic concerning laboratory management and resources, for example, catalogues of biological resources for use in the lab including cell lines, viruses, plasmids, phages, DNA probes and primers and so on.",false,,,http://edamontology.org/topic_3071,beta12orEarlier,,,,,,,,,edamontology:topic_0607,,,,,,,,,,,,,,,,,,topic,,,,,,http://edamontology.org/topic_3071,,,,"Topic concerning laboratory management and resources, for example, catalogues of biological resources for use in the lab including cell lines, viruses, plasmids, phages, DNA probes and primers and so on.",,Laboratory resources,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_1317,Structural biology,Structural determination|Structure determination|Structural assignment,"This includes experimental methods for biomolecular structure determination, such as X-ray crystallography, nuclear magnetic resonance (NMR), circular dichroism (CD) spectroscopy, microscopy etc., including the assignment or modelling of molecular structure from such data.|Topic concerning the molecular structure of biological molecules, particularly macromolecules such as proteins and nucleic acids.",false,,,http://edamontology.org/topic_3070,1.3,,,,,,,,,edamontology:topic_1317,,,,,,,,,,,,,,,,,,topic,,,,,,"This includes Informatics concerning data generated from the use of microscopes, including optical, electron and scanning probe microscopy.  Includes methods for digitizing microscope images and viewing the produced virtual slides and associated data on a computer screen.",,,,"Topic concerning the molecular structure of biological molecules, particularly macromolecules such as proteins and nucleic acids.",,Structural determination|Structure determination|Structural assignment,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3365,Data analysis,,"Topic concerning the process of systematically applying statistical and / or logical techniques to describe and illustrate, condense and recap, and evaluate data.",false,,,http://edamontology.org/topic_3071,1.4,,,,,,,,,edamontology:topic_3365,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the process of systematically applying statistical and / or logical techniques to describe and illustrate, condense and recap, and evaluate data.",,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3053,Genetics,Gene database|Gene resource|http://purl.bioontology.org/ontology/MSH/D005823|Genetics data resources,"Topic concerning the study of genes, genetic variation and heredity in living organisms.",false,,,http://edamontology.org/topic_3070,beta13,,,,,,,,,edamontology:topic_3053,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the study of genes, genetic variation and heredity in living organisms.",http://purl.bioontology.org/ontology/MSH/D005823|Genetics data resources,Gene database|Gene resource,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_2820,Vertebrates,,"The resource may be specific to a vertebrate, a group of vertebrates or all vertebrates.|Topic concerning vertebrates, e.g. information on a specific vertebrate genome including molecular sequences, genes and annotation.",false,,,http://edamontology.org/topic_2818,beta12orEarlier,,,,,,,,,edamontology:topic_2820,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning vertebrates, e.g. information on a specific vertebrate genome including molecular sequences, genes and annotation.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0218,Text mining,Literature analysis|Text data mining|Literature mining,Topic concerning the analysis of the biomedical and informatics literature.,false,,,http://edamontology.org/topic_3068,beta12orEarlier,,,,,,,,,edamontology:topic_0218,,,,,,,,,,,,,,,,,,topic,,,,,,,,Literature analysis,BioCatalogue:Document Similarity|BioCatalogue:Document Clustering|BioCatalogue:Named Entity Recognition|BioCatalogue:Text Mining,Topic concerning the analysis of the biomedical and informatics literature.,Text data mining|Literature mining,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3439,Advice and advocacy,,"Topic concerning support for or recommendation of a particular course of action, cause or policy.",false,,,http://edamontology.org/topic_3364,1.4,,,,,,,,,edamontology:topic_3439,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning support for or recommendation of a particular course of action, cause or policy.",,,,,http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3064,Developmental biology,,Topic concerning how organisms grow and develop.,false,,,http://edamontology.org/topic_3070,beta13,,,,,,,,,edamontology:topic_3064,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning how organisms grow and develop.,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0594,Sequence classification,,"Methods including sequence motifs, profile and other diagnostic elements which (typically) represent conserved patterns (of residues or properties) in molecular sequences.|Topic concerning the classification of molecular sequences based on some measure of their similarity.",false,,,http://edamontology.org/topic_0080,beta12orEarlier,,,,,,,,,edamontology:topic_0594,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the classification of molecular sequences based on some measure of their similarity.,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3339,Microbial collection,,"Topic concerning collections of microbial cells including bacteria, yeasts and moulds.",false,,,http://edamontology.org/topic_3277,1.3,,,,,,,,,edamontology:topic_3339,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning collections of microbial cells including bacteria, yeasts and moulds.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3063,Medical informatics,Molecular medicine|Translational medicine|Health informatics|Clinical informatics|Healthcare informatics|Health and disease|Biomedical informatics,"Topic concerning the application of information technology to health, disease and biomedicine.",false,,,http://edamontology.org/topic_3303|http://edamontology.org/topic_3316,beta13,,,,,,,,,edamontology:topic_3063,,,,,,,,,,,,,,,,,,topic,,,,,,,,Molecular medicine|Translational medicine,,"Topic concerning the application of information technology to health, disease and biomedicine.",Health informatics|Clinical informatics|Healthcare informatics|Health and disease|Biomedical informatics,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3426,Economics,,"Topic concerning the production, consumption and transfer of wealth.",false,,,http://edamontology.org/topic_3364,1.4,,,,,,,,,edamontology:topic_3426,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the production, consumption and transfer of wealth.",,,,,http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_2818,Eukaryotes,Eukaryote,"The resource may be specific to a eukaryote, a group of eukaryotes or all eukaryotes.|Topic concerning eukaryotes or data concerning eukaryotes, e.g. information on a specific eukaryote genome including molecular sequences, genes and annotation.",false,,,http://edamontology.org/topic_0621,beta12orEarlier,,,,,,,,,edamontology:topic_2818,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning eukaryotes or data concerning eukaryotes, e.g. information on a specific eukaryote genome including molecular sequences, genes and annotation.",Eukaryote,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_2828,X-ray crystallography,Crystallography,Topic concerning the study of crystals and their structure by means of the diffraction of X-rays by the regularly spaced atoms of crystalline materials.,false,,,http://edamontology.org/topic_3382|http://edamontology.org/topic_1317,beta12orEarlier,,,,,,,,,edamontology:topic_2828,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the study of crystals and their structure by means of the diffraction of X-rays by the regularly spaced atoms of crystalline materials.,Crystallography,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3406,"Ear, nose and throat medicine",Head and neck disorders|Audiovestibular medicine|Otolaryngology,"Topic concerning the branch of medicine that deals with the prevention, diagnosis, and treatment of disorders of the ear, nose and throat.",false,,,http://edamontology.org/topic_3303,1.4,,,,,,,,,edamontology:topic_3406,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the branch of medicine that deals with the prevention, diagnosis, and treatment of disorders of the ear, nose and throat.",Audiovestibular medicine|Otolaryngology,Head and neck disorders,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3418,Paediatrics,Child health,"Topic concerning the branch of medicine that deals with the medical care of infants, children and adolescents.",false,,,http://edamontology.org/topic_3303,1.4,,,,,,,,,edamontology:topic_3418,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the branch of medicine that deals with the medical care of infants, children and adolescents.",Child health,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3047,Molecular biology,,"Topic concerning the molecular basis of biological activity, particularly the macromolecules (e.g. proteins and nucleic acids) that are essential to life.",false,,,http://edamontology.org/topic_3070,beta13,,,,,,,,,edamontology:topic_3047,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the molecular basis of biological activity, particularly the macromolecules (e.g. proteins and nucleic acids) that are essential to life.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0208,Pharmacogenomics,,"Topic concerning the influence of genotype on drug response, for example by correlating gene expression or single-nucleotide polymorphisms with drug efficacy or toxicity.",false,,,http://edamontology.org/topic_0202|http://edamontology.org/topic_0622,beta12orEarlier,,,,,,,,,edamontology:topic_0208,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the influence of genotype on drug response, for example by correlating gene expression or single-nucleotide polymorphisms with drug efficacy or toxicity.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3402,Anaesthesiology,Anaesthetics,Topic concerning anaesthesia and anaesthetics.,false,,,http://edamontology.org/topic_3303,1.4,,,,,,,,,edamontology:topic_3402,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning anaesthesia and anaesthetics.,Anaesthetics,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3390,Nutritional science,Nutrition science,"Topic concerning the study of the effects of food components on the metabolism, health, performance and disease resistance of humans and animals.  It also includes the study of human behaviours related to food choices.",false,,,http://edamontology.org/topic_3344,1.4,,,,,,,,,edamontology:topic_3390,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the study of the effects of food components on the metabolism, health, performance and disease resistance of humans and animals.  It also includes the study of human behaviours related to food choices.",Nutrition science,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3423,Complementary medicine,Alternative medicine|Holistic medicine,Topic concerning medical therapies that fall beyond the scope of conventional medicine but may be used alongside it in the treatment of disease and ill health.,false,,,http://edamontology.org/topic_3303,1.4,,,,,,,,,edamontology:topic_3423,,,,,,,,,,,,,,,,,,,,,,,,,,Alternative medicine|Holistic medicine,,Topic concerning medical therapies that fall beyond the scope of conventional medicine but may be used alongside it in the treatment of disease and ill health.,,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3372,Computer programming,Software development,Topic concerning the process that leads from an original formulation of a computing problem to executable programs.,false,,,http://edamontology.org/topic_3316,1.4,,,,,,,,,edamontology:topic_3372,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the process that leads from an original formulation of a computing problem to executable programs.,Software development,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0754,Signaling pathways,,Topic concerning signaling pathways.,false,,,http://edamontology.org/topic_0602,beta12orEarlier,,,,,,,,,edamontology:topic_0754,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning signaling pathways.,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3305,Public health and epidemiology,Public health|Epidemiology,,false,,,http://edamontology.org/topic_3303,1.3,,,,,,,,,edamontology:topic_3305,,,,,,,,,,,,,,,,,,topic,,,,,,,"Topic concerning the the patterns, cause, and effect of disease within populations.",,,,,Public health|Epidemiology,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3363,Cognitive science,Lab techniques,"Topic concerning the study of thought, learning, and mental organisation, which draws on aspects of psychology, linguistics, philosophy and computer modelling.",false,,,http://www.w3.org/2002/07/owl#Thing,1.4,,,,,,,,,edamontology:topic_3363,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the study of thought, learning, and mental organisation, which draws on aspects of psychology, linguistics, philosophy and computer modelling.",Lab techniques,,,,http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0204,Gene regulation,,Topic concerning primarily the regulation of gene expression.,false,,,http://edamontology.org/topic_0203,beta12orEarlier,,,,,,,,,edamontology:topic_0204,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning primarily the regulation of gene expression.,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0724,Protein families,Protein secondary databases|Protein sequence classification,"A protein families database might include the classifier (e.g. a sequence profile) used to build the classification.|Topic concerning primarily the classification of proteins (from sequence or structural data) into clusters, groups, families etc., curation of a particular protein or protein family, or any other proteins that have been classified as members of a common group.",false,,,http://edamontology.org/topic_0594|http://edamontology.org/topic_0078,beta12orEarlier,,,,,,,,,edamontology:topic_0724,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning primarily the classification of proteins (from sequence or structural data) into clusters, groups, families etc., curation of a particular protein or protein family, or any other proteins that have been classified as members of a common group.",,Protein secondary databases|Protein sequence classification,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3404,Dermatology,Dermatological disorders,"Topic concerning the branch of medicine that deals with prevention, diagnosis and treatment of disorders of the skin, scalp, hair and nails.",false,,,http://edamontology.org/topic_3303,1.4,,,,,,,,,edamontology:topic_3404,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the branch of medicine that deals with prevention, diagnosis and treatment of disorders of the skin, scalp, hair and nails.",,Dermatological disorders,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0610,Ecology,Ecoinformatics|Ecological informatics|Computational ecology|http://purl.bioontology.org/ontology/MSH/D004777|Environmental science,Topic concerning the ecological and environmental sciences and especially the application of information technology (ecoinformatics).,false,,,http://edamontology.org/topic_3070,beta12orEarlier,,,,,,,,,edamontology:topic_0610,,,,,,,,,,,,,,,,,,topic,,,,,,,,Environmental science,,Topic concerning the ecological and environmental sciences and especially the application of information technology (ecoinformatics).,,Ecoinformatics|Ecological informatics|Computational ecology,http://purl.bioontology.org/ontology/MSH/D004777,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3297,Biotechnology,,"Topic concerning the exploitation of biological process, structure and function for industrial purposes, for example the genetic manipulation of microorganisms for the antibody production.",false,,,http://edamontology.org/topic_3070,1.3,,,,,,,,,edamontology:topic_3297,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the exploitation of biological process, structure and function for industrial purposes, for example the genetic manipulation of microorganisms for the antibody production.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0078,Proteins,http://purl.bioontology.org/ontology/MSH/D020539|Protein databases|Protein bioinformatics|Protein informatics|Protein analysis,"Topic concerning archival, processing and analysis of protein data, typically molecular sequence and structural data.",false,,,http://edamontology.org/topic_3292,beta12orEarlier,,,,,,,,,edamontology:topic_0078,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning archival, processing and analysis of protein data, typically molecular sequence and structural data.",Protein bioinformatics|Protein informatics|Protein analysis,http://purl.bioontology.org/ontology/MSH/D020539|Protein databases,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0780,Plants,Plant biology|Botany|Plant,"The resource may be specific to a plant, a group of plants or all plants.|Topic concerning plants, e.g. information on a specific plant genome including molecular sequences, genes and annotation.",false,,,http://edamontology.org/topic_2818,beta12orEarlier,,,,,,,,,edamontology:topic_0780,,,,,,,,,,,,,,,,,,topic,,,,,,,,Plant biology|Botany,,"Topic concerning plants, e.g. information on a specific plant genome including molecular sequences, genes and annotation.",Plant,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0804,Immunology,Computational immunology|Immunoinformatics|http://purl.bioontology.org/ontology/MSH/D007125|http://purl.bioontology.org/ontology/MSH/D007120,"Topic concerning the application of information technology to immunology such as immunological processes, immunological genes, proteins and peptide ligands, antigens and so on.",false,,,http://edamontology.org/topic_3344,beta12orEarlier,,,,,,,,,edamontology:topic_0804,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the application of information technology to immunology such as immunological processes, immunological genes, proteins and peptide ligands, antigens and so on.",,Computational immunology|Immunoinformatics,http://purl.bioontology.org/ontology/MSH/D007125|http://purl.bioontology.org/ontology/MSH/D007120,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0092,Data visualisation,Data plotting|Data rendering|Data rendering and visualisation,"Topic for the plotting or rendering (drawing on a computer screen) of molecular sequences, structures or other biomolecular data.",false,,,http://edamontology.org/topic_3071,beta12orEarlier,,,,,,,,,edamontology:topic_0092,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic for the plotting or rendering (drawing on a computer screen) of molecular sequences, structures or other biomolecular data.",Data plotting|Data rendering|Data rendering and visualisation,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3416,Musculoskeletal medicine,Musculoskeletal disorders,"Topic concerning the branch of medicine that deals with the prevention, diagnosis, and treatment of disorders of the muscle, bone and connective tissue.  It incorporates aspects of orthopaedics, rheumatology, rehabilitation medicine and pain medicine.",false,,,http://edamontology.org/topic_3303,1.4,,,,,,,,,edamontology:topic_3416,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the branch of medicine that deals with the prevention, diagnosis, and treatment of disorders of the muscle, bone and connective tissue.  It incorporates aspects of orthopaedics, rheumatology, rehabilitation medicine and pain medicine.",,Musculoskeletal disorders,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0114,Gene structure,,"This includes the study of promoters, coding regions etc.|Topic concerning resources that aim to identify, predict, model, analyse or curate gene structure in DNA sequences.  This includes introns, exons, and gene fusion.",false,,,http://edamontology.org/topic_3321,beta12orEarlier,,,,,,,,,edamontology:topic_0114,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning resources that aim to identify, predict, model, analyse or curate gene structure in DNA sequences.  This includes introns, exons, and gene fusion.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3173,Epigenomics,http://purl.bioontology.org/ontology/MSH/D057890,"Epigenetics concerns the heritable changes in gene expression owing to mechanisms other than DNA sequence variation.|Topic concerning the study of the epigenetic modifications of a whole cell, tissue, organism etc.",false,,,http://edamontology.org/topic_0622|http://edamontology.org/topic_3295,1.1,,,,,,,,,edamontology:topic_3173,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the study of the epigenetic modifications of a whole cell, tissue, organism etc.",http://purl.bioontology.org/ontology/MSH/D057890,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3386,Laboratory animal science,,Topic concerning the use of animals and alternatives in experimental research.,false,,,http://edamontology.org/topic_3344,1.4,,,,,,,,,edamontology:topic_3386,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the use of animals and alternatives in experimental research.,,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_2661,Toxins and targets,Targets|Toxins,Topic concerning structural and associated data for toxic chemical substances.,false,,,http://edamontology.org/topic_2840|http://edamontology.org/topic_0154,beta12orEarlier,,,,,,,,,edamontology:topic_2661,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning structural and associated data for toxic chemical substances.,,Targets|Toxins,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0134,Mass spectrometry,,Topic concerning an analytical chemistry technique that measures the mass-to-charge ratio and abundance of irons in the gas phase.,false,,,http://edamontology.org/topic_3361,beta12orEarlier,,,,,,,,,edamontology:topic_0134,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning an analytical chemistry technique that measures the mass-to-charge ratio and abundance of irons in the gas phase.,,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3392,Psychology,,Topic concerning the scientific study of the human mind.,false,,,http://edamontology.org/topic_3363,1.4,,,,,,,,,edamontology:topic_3392,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the scientific study of the human mind.,,,,,http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3055,Quantitative genetics,,Topic concerning the genes and genetic mechanisms such as Mendelian inheritance that underly continuous phenotypic traits (such as height or weight).,false,,,http://edamontology.org/topic_0625,beta13,,,,,,,,,edamontology:topic_3055,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the genes and genetic mechanisms such as Mendelian inheritance that underly continuous phenotypic traits (such as height or weight).,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3432,Presentation skills,,Topic concerning the ability to create and deliver engaging verbal presentations.,false,,,http://edamontology.org/topic_3436,1.4,,,,,,,,,edamontology:topic_3432,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the ability to create and deliver engaging verbal presentations.,,,,,http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0749,Transcription factors and regulatory sites,Transcriptional regulatory sites|Transcription factors|Transcription factor binding sites,"Transcription factor proteins either promote (as an activator) or block (as a repressor) the binding to DNA of RNA polymerase.  Regulatory sites including transcription factor binding site as well as promoters, enhancers, silencers and boundary elements / insulators.|Topic concerning proteins that bind to DNA and control transcription of DNA to mRNA (transcription factors) and also transcriptional regulatory sites, elements and regions (such as promoters, enhancers, silencers and boundary elements / insulators) in nucleotide sequences.",false,,,http://edamontology.org/topic_0724|http://edamontology.org/topic_0203,beta12orEarlier,,,,,,,,,edamontology:topic_0749,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Transcription Factors,"Topic concerning proteins that bind to DNA and control transcription of DNA to mRNA (transcription factors) and also transcriptional regulatory sites, elements and regions (such as promoters, enhancers, silencers and boundary elements / insulators) in nucleotide sequences.",,Transcriptional regulatory sites|Transcription factors|Transcription factor binding sites,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0085,Functional genomics,,"Topic concerning the study of gene or protein functions and their interactions in totality in a given organism, tissue, cell etc.",false,,,http://edamontology.org/topic_0622|http://edamontology.org/topic_1775,beta12orEarlier,,,,,,,,,edamontology:topic_0085,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Functional Genomics,"Topic concerning the study of gene or protein functions and their interactions in totality in a given organism, tissue, cell etc.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3399,Geriatric medicine,Ageing|Aging|Geriatrics,"Topic concerning the branch of medicine dealing with the diagnosis, treatment and prevention of disease in older people, and the problems specific to aging.",false,,,http://edamontology.org/topic_3303,1.4,,,,,,,,,edamontology:topic_3399,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the branch of medicine dealing with the diagnosis, treatment and prevention of disease in older people, and the problems specific to aging.",Ageing|Aging|Geriatrics,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3395,Regnerative medicine,Stem cell research,Topic concerning biomedical approaches to clinical interventions that involve the use of stem cells.,false,,,http://edamontology.org/topic_3344,1.4,,,,,,,,,edamontology:topic_3395,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning biomedical approaches to clinical interventions that involve the use of stem cells.,Stem cell research,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3306,Biophysics,,Topic concerning the use of physics to study biological system.,false,,,http://edamontology.org/topic_3070|http://edamontology.org/topic_3318,1.3,,,,,,,,,edamontology:topic_3306,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the use of physics to study biological system.,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0160,"Sequence sites, features and motifs",Sequence motifs|Functional sites|Sequence sites|Sequence profiles|Protein functional sites|Sequence features|Protein sequence features|Sequence feature detection|HMMs,"Topic concerning the archival, detection, prediction and analysis of
positional features such as functional and other key sites, in molecular sequences and the conserved patterns (motifs, profiles etc.) that may be used to describe them.",false,,,http://edamontology.org/topic_0080,beta12orEarlier,,,,,,,,,edamontology:topic_0160,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the archival, detection, prediction and analysis of
positional features such as functional and other key sites, in molecular sequences and the conserved patterns (motifs, profiles etc.) that may be used to describe them.",,Sequence motifs|Functional sites|Sequence sites|Sequence profiles|Protein functional sites|Sequence features|Protein sequence features|Sequence feature detection|HMMs,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3384,Medical imaging,,Topic concerning the use of imaging techniques for clinical purposes for medical research.,false,,,http://edamontology.org/topic_3382,1.4,,,,,,,,,edamontology:topic_3384,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the use of imaging techniques for clinical purposes for medical research.,,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3293,Phylogenetics,http://purl.bioontology.org/ontology/MSH/D010802,Topic concerning the study of evolutionary relationships amongst organisms from analysis of genetic information (typically gene or protein sequences).,false,,,http://edamontology.org/topic_0080|http://edamontology.org/topic_0084,1.3,,,,,,,,,edamontology:topic_3293,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the study of evolutionary relationships amongst organisms from analysis of genetic information (typically gene or protein sequences).,,http://purl.bioontology.org/ontology/MSH/D010802,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3366,Data integration,,Topic concerning the combination of data from different sources to provide users with a unified view of these data.,false,,,http://edamontology.org/topic_3071,1.4,,,,,,,,,edamontology:topic_3366,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the combination of data from different sources to provide users with a unified view of these data.,,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0166,Protein structural motifs and surfaces,Protein structural motifs|Structural motifs|Protein structural features|Protein surfaces,"This includes solvent-exposed surfaces, internal cavities, the analysis of shape, hydropathy, electrostatic patches and so on.|Topic concerning (3D) structural features or common 3D motifs within protein structures, including the surface of a protein structure, such as biological interfaces with other molecules.",false,,,http://edamontology.org/topic_2814,beta12orEarlier,,,,,,,,,edamontology:topic_0166,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning (3D) structural features or common 3D motifs within protein structures, including the surface of a protein structure, such as biological interfaces with other molecules.",,Protein structural motifs|Structural motifs|Protein structural features|Protein surfaces,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3263,Data security,Security|Privacy|Security,"Topic concerning the protection of data, for example, patient health data.",false,,,http://edamontology.org/topic_3071,1.3,,,,,,,,,edamontology:topic_3263,,,,,,,,,,,,,,,,,,topic,,,,,,,,Security,,"Topic concerning the protection of data, for example, patient health data.",Privacy|Security,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0199,Genetic variation,Polymorphism|Mutation|http://purl.bioontology.org/ontology/MSH/D014644|DNA variation,Topic concerning DNA sequence variation (mutation and polymorphism) data.,false,,,http://edamontology.org/topic_0625,beta12orEarlier,,,,,,,,,edamontology:topic_0199,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning DNA sequence variation (mutation and polymorphism) data.,http://purl.bioontology.org/ontology/MSH/D014644|DNA variation,Polymorphism|Mutation,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0655,Coding RNA,EST|cDNA|mRNA,"Topic concerning messenger RNA (mRNA), expressed sequence tag (EST) or complementary DNA (cDNA) sequences.",false,,,http://edamontology.org/topic_0099,beta12orEarlier,,,,,,,,,edamontology:topic_0655,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning messenger RNA (mRNA), expressed sequence tag (EST) or complementary DNA (cDNA) sequences.",,EST|cDNA|mRNA,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3440,Marketing,,Topic concerning the promotion and sale of products and services including market research and advertising. ,false,,,http://edamontology.org/topic_3364,1.4,,,,,,,,,edamontology:topic_3440,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the promotion and sale of products and services including market research and advertising. ,,,,,http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_2258,Cheminformatics,Chemical informatics|Chemoinformatics,Topic concerning the application of information technology to chemistry in biological research environment.,false,,,http://edamontology.org/topic_3314|http://edamontology.org/topic_3316,beta12orEarlier,,,,,,,,,edamontology:topic_2258,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Chemoinformatics,Topic concerning the application of information technology to chemistry in biological research environment.,Chemical informatics|Chemoinformatics,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3277,Sample collections,biosamples|samples|Specimen collections|biobanking,Topic concerning biological samples and specimens.,false,,,http://edamontology.org/topic_3344,1.3,,,,,,,,,edamontology:topic_3277,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning biological samples and specimens.,Specimen collections|biobanking,biosamples|samples,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3375,Pharmacokinetics and pharmacodynamics,Drug distribution|Pharmacokinetics|Pharmacodynamics|Drug excretion|Drug metabolism|Drug absorption|Drug metabolism|ADME,Topic concerning the study of how a drug interacts with the body.,false,,,http://edamontology.org/topic_3376,1.4,,,,,,,,,edamontology:topic_3375,,,,,,,,,,,,,,,,,,,,,,,,,,Drug metabolism,,Topic concerning the study of how a drug interacts with the body.,ADME,Drug distribution|Pharmacokinetics|Pharmacodynamics|Drug excretion|Drug metabolism|Drug absorption,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3071,Data management,http://purl.bioontology.org/ontology/MSH/D030541|Data handling|Knowledge management|Databases|Databases,"Topic concerning the general handling of data stored in digital archives such as databanks, databases proper, web portals and other data resources.",false,,,http://www.w3.org/2002/07/owl#Thing,beta13,,,,,,,,,edamontology:topic_3071,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the general handling of data stored in digital archives such as databanks, databases proper, web portals and other data resources.",Databases,http://purl.bioontology.org/ontology/MSH/D030541|Data handling|Knowledge management|Databases,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3400,"Allergy, clinical immunology and immunotherapeutics.",Clinical immunology|Immunomodulators|Immunotherapeutics|Immune disorders|Allergy,"Topic concerning health issues related to the immune system and their prevention, diagnosis and mangement.",false,,,http://edamontology.org/topic_3303,1.4,,,,,,,,,edamontology:topic_3400,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning health issues related to the immune system and their prevention, diagnosis and mangement.",,Clinical immunology|Immunomodulators|Immunotherapeutics|Immune disorders|Allergy,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3376,Medicines research and development,Health care research|Drug discovery and development,"Topic concerning the discovery, development and approval of medicines.",false,,,http://edamontology.org/topic_3344,1.4,,,,,,,,,edamontology:topic_3376,,,,,,,,,,,,,,,,,,,,,,,,,,Health care research,,"Topic concerning the discovery, development and approval of medicines.",Drug discovery and development,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_2814,Protein structure analysis,Protein structure,Topic concerning protein secondary or tertiary structural data and/or associated annotation.,false,,,http://edamontology.org/topic_0081,beta12orEarlier,,,,,,,,,edamontology:topic_2814,,,,,,,,,,,,,,,,,,topic,,,,,,,http://edamontology.org/topic_3040,,,Topic concerning protein secondary or tertiary structural data and/or associated annotation.,Protein structure,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3385,Light microscopy,,Topic concerning the use of optical instruments to magnify the image of an object.,false,,,http://edamontology.org/topic_3382,1.4,,,,,,,,,edamontology:topic_3385,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the use of optical instruments to magnify the image of an object.,,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_2846,Gene regulatory networks,,Topic concerning gene regulatory networks.,false,,,http://edamontology.org/topic_0602|http://edamontology.org/topic_0204,beta12orEarlier,,,,,,,,,edamontology:topic_2846,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning gene regulatory networks.,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0611,Electron microscopy,,Topic concerning the use of electrons to analyse structures at resolutions higher than can be achieved using light.,false,,,http://edamontology.org/topic_3382|http://edamontology.org/topic_1317,beta12orEarlier,,,,,,,,,edamontology:topic_0611,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the use of electrons to analyse structures at resolutions higher than can be achieved using light.,,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3383,Biological imaging,,Topic concerning the use of imaging techniques to understand biology.,false,,,http://edamontology.org/topic_3382,1.4,,,,,,,,,edamontology:topic_3383,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the use of imaging techniques to understand biology.,,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3370,Analytical chemistry,,"Topic concerning the study of the separation, identification, and quantification of the chemical components of natural and artificial materials.",false,,,http://edamontology.org/topic_3314,1.4,,,,,,,,,edamontology:topic_3370,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the study of the separation, identification, and quantification of the chemical components of natural and artificial materials.",,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3435,Training for trainers,,Topic concerning the ability to train people to facilitate learning in others.,false,,,http://edamontology.org/topic_3364,1.4,,,,,,,,,edamontology:topic_3435,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the ability to train people to facilitate learning in others.,,,,,http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3303,Medicine,Experimental medicine|Biomedical research,"Topic concerning research in support of healing by diagnosis, treatment, and prevention of disease.",false,,,http://www.w3.org/2002/07/owl#Thing,1.3,,,,,,,,,edamontology:topic_3303,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning research in support of healing by diagnosis, treatment, and prevention of disease.",Experimental medicine|Biomedical research,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3436,Communication skills,,"Topic concerning the activity of conveying information through the exchange of thoughts, messages or information as by speech, visuals, signals, writing or behaviour.",false,,,http://edamontology.org/topic_3364,1.4,,,,,,,,,edamontology:topic_3436,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the activity of conveying information through the exchange of thoughts, messages or information as by speech, visuals, signals, writing or behaviour.",,,,,http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3407,Endocrinology and metabolism,Metabolic disorders|Endocrine disorders|Endocrinology|Metabolism,"Topic concerning the branch of medicine dealing with diseases of endocrine organs, hormone systems, their target organs, and disorders of the pathways of glucose and lipid metabolism.",false,,,http://edamontology.org/topic_3303,1.4,,,,,,,,,edamontology:topic_3407,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the branch of medicine dealing with diseases of endocrine organs, hormone systems, their target organs, and disorders of the pathways of glucose and lipid metabolism.",,Metabolic disorders|Endocrine disorders|Endocrinology|Metabolism,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3373,Drug development,Medicines development|Drug development science|Medicine development,Topic concerning the process of bringing a new drug to market once a lead compounds has been identified through drug discovery.,false,,,http://edamontology.org/topic_3376,1.4,,,,,,,,,edamontology:topic_3373,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the process of bringing a new drug to market once a lead compounds has been identified through drug discovery.,Medicines development|Drug development science|Medicine development,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3425,Entrepeneurship,,Topic concerning the process of starting a business or other organisation.,false,,,http://edamontology.org/topic_3364,1.4,,,,,,,,,edamontology:topic_3425,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the process of starting a business or other organisation.,,,,,http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3175,Structural variation,Genomic structural variation,"Topic concerning variation in chromosome structure including microscopic and submicroscopic types of variation such as deletions, duplications, copy-number variants, insertions, inversions and translocations.",false,,,http://edamontology.org/topic_0199,1.1,,,,,,,,,edamontology:topic_3175,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning variation in chromosome structure including microscopic and submicroscopic types of variation such as deletions, duplications, copy-number variants, insertions, inversions and translocations.",Genomic structural variation,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3292,Biochemistry,Chemical biology|Biological chemistry,Topic concerning chemical substances and physico-chemical processes and that occur within living organisms.,false,,,http://edamontology.org/topic_3314|http://edamontology.org/topic_3070,1.3,,,,,,,,,edamontology:topic_3292,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning chemical substances and physico-chemical processes and that occur within living organisms.,Chemical biology|Biological chemistry,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3389,Nanotechnology,Nanoscience,Topic concerning the manipulation of matter at an atomic level.,false,,,http://edamontology.org/topic_3362,1.4,,,,,,,,,edamontology:topic_3389,,,,,,,,,,,,,,,,,,,,,,,,,,Nanoscience,,Topic concerning the manipulation of matter at an atomic level.,,,,,http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3337,Biobank,Tissue collection|biobanking,"Topic concerning repositories of biological samples, typically human, for basic biological and clinical research.",false,,,http://edamontology.org/topic_3277,1.3,,,,,,,,,edamontology:topic_3337,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning repositories of biological samples, typically human, for basic biological and clinical research.",Tissue collection|biobanking,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0753,Metabolic pathways,,Topic concerning metabolic pathways.,false,,,http://edamontology.org/topic_0602,beta12orEarlier,,,,,,,,,edamontology:topic_0753,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning metabolic pathways.,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3168,Sequencing,http://purl.bioontology.org/ontology/MSH/D059014|Next generation sequencing|Next gen sequencing,"Topic concerning the determination of complete (typically nucleotide) sequences, including those of genomes (full genome sequencing, de novo sequencing and resequencing), amplicons and transcriptomes.",false,,,http://edamontology.org/topic_3361,1.1,,,,,,,,,edamontology:topic_3168,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the determination of complete (typically nucleotide) sequences, including those of genomes (full genome sequencing, de novo sequencing and resequencing), amplicons and transcriptomes.",,http://purl.bioontology.org/ontology/MSH/D059014|Next generation sequencing|Next gen sequencing,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0177,Molecular docking,,Topic concerning the modelling the structure of proteins in complex with small molecules or other macromolecules.,false,,,http://edamontology.org/topic_0082,beta12orEarlier,,,,,,,,,edamontology:topic_0177,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the modelling the structure of proteins in complex with small molecules or other macromolecules.,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3316,Computer science,,Topic concerning the theory and practical use of computer systems.,false,,,http://www.w3.org/2002/07/owl#Thing,1.3,,,,,,,,,edamontology:topic_3316,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the theory and practical use of computer systems.,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3304,Neurobiology,Neuroscience,"Topic concerning the study of the nervous system and brain; its anatomy, physiology and function.",false,,,http://edamontology.org/topic_3344,1.3,,,,,,,,,edamontology:topic_3304,,,,,,,,,,,,,,,,,,topic,,,,,,,,Neuroscience,,"Topic concerning the study of the nervous system and brain; its anatomy, physiology and function.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0079,Metabolites,Metabolite structures,"This concept excludes macromolecules such as proteins and nucleic acids.|Topic concerning the structures of reactants or products of metabolism, for example small molecules such as including vitamins, polyols, nucleotides and amino acids.",false,,,http://edamontology.org/topic_0154,beta12orEarlier,,,,,,,,,edamontology:topic_0079,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the structures of reactants or products of metabolism, for example small molecules such as including vitamins, polyols, nucleotides and amino acids.",Metabolite structures,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0164,Sequence clustering,Sequence clusters,"This includes systems that generate, process and analyse sequence clusters.|Topic concerning the comparison and grouping together of molecular sequences on the basis of their similarities.",false,,,http://edamontology.org/topic_0159,beta12orEarlier,,,,,,,,,edamontology:topic_0164,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the comparison and grouping together of molecular sequences on the basis of their similarities.,Sequence clusters,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0090,"Data search, query and retrieval",Data search|Data retrieval|Data query,"This includes, for example, search, query and retrieval of molecular sequences and associated data.|Topic concerning the search and query of data sources (typically biological databases or ontologies) in order to retrieve entries or other information.",false,,,http://edamontology.org/topic_3071,beta12orEarlier,,,,,,,,,edamontology:topic_0090,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Data Retrieval|BioCatalogue:Identifier Retrieval|BioCatalogue:Structure Retrieval|BioCatalogue:Image Retrieval|BioCatalogue:Sequence Retrieval,Topic concerning the search and query of data sources (typically biological databases or ontologies) in order to retrieve entries or other information.,Data retrieval|Data query,Data search,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3344,Biomedical science,Topic concerning biological science that is (typically) performed in the context of medicine.,,false,,,http://edamontology.org/topic_3303|http://edamontology.org/topic_3070,1.3,,,,,,,,,edamontology:topic_3344,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,,Topic concerning biological science that is (typically) performed in the context of medicine.,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3176,DNA packaging,http://purl.bioontology.org/ontology/MSH/D042003,"Topic concerning DNA-histone complexes (chromatin), organisation of chromatin into nucleosomes and packaging into higher-order structures.",false,,,http://edamontology.org/topic_0654,beta12orEarlier,,,,,,,,,edamontology:topic_3176,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning DNA-histone complexes (chromatin), organisation of chromatin into nucleosomes and packaging into higher-order structures.",http://purl.bioontology.org/ontology/MSH/D042003,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0140,Protein targeting and localization,Protein targeting|Protein sorting|Protein localization,"Topic concerning the study of how proteins are transported within and without the cell, including signal peptides, protein subcellular localization and export.",false,,,http://edamontology.org/topic_0108,beta12orEarlier,,,,,,,,,edamontology:topic_0140,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the study of how proteins are transported within and without the cell, including signal peptides, protein subcellular localization and export.",,Protein targeting|Protein sorting|Protein localization,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3172,Metabolomics,http://purl.bioontology.org/ontology/MSH/D055432,"Topic concerning the systematic study of metabolites, the chemical processes they are involved, and the chemical fingerprints of specific cellular processes in a whole cell, tissue, organ or organism.",false,,,http://edamontology.org/topic_3391,1.1,,,,,,,,,edamontology:topic_3172,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the systematic study of metabolites, the chemical processes they are involved, and the chemical fingerprints of specific cellular processes in a whole cell, tissue, organ or organism.",http://purl.bioontology.org/ontology/MSH/D055432,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3070,Biology,Biological science,"Topic concerning a particular biological science, especially observable traits such as aspects of biochemistry, physiology, morphology, anatomy, development and so on.",false,,,http://www.w3.org/2002/07/owl#Thing,beta13,,,,,,,,,edamontology:topic_3070,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning a particular biological science, especially observable traits such as aspects of biochemistry, physiology, morphology, anatomy, development and so on.",Biological science,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0209,Medicinal chemistry,Drug design,"This includes methods that search compound collections, generate or analyse drug 3D conformations, identify drug targets with structural docking etc.|Topic concerning the design and chemical synthesis of bioactive molecules, for example drugs or potential drug compounds, for medicinal purposes.",false,,,http://edamontology.org/topic_3371|http://edamontology.org/topic_3336,beta12orEarlier,,,,,,,,,edamontology:topic_0209,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the design and chemical synthesis of bioactive molecules, for example drugs or potential drug compounds, for medicinal purposes.",Drug design,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0194,Phylogenomics,,"Topic concerning the integrated study of evolutionary relationships and whole genome data, for example, in the analysis of species trees, horizontal gene transfer and evolutionary reconstruction.",false,,,http://edamontology.org/topic_0622|http://edamontology.org/topic_3293,beta12orEarlier,,,,,,,,,edamontology:topic_0194,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the integrated study of evolutionary relationships and whole genome data, for example, in the analysis of species trees, horizontal gene transfer and evolutionary reconstruction.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0593,NMR spectroscopy,Spectroscopy|Nuclear magnetic resonance spectroscopy|NMR,"Topic concerning an analytical technique that exploits the magenetic properties of certain atomic nuclei to provide information on the structure, dynamics, reaction state and chemical environment of molecules.",false,,,http://edamontology.org/topic_3382|http://edamontology.org/topic_1317,beta12orEarlier,,,,,,,,,edamontology:topic_0593,,,,,,,,,,,,,,,,,,,,,,,,,,Spectroscopy,,"Topic concerning an analytical technique that exploits the magenetic properties of certain atomic nuclei to provide information on the structure, dynamics, reaction state and chemical environment of molecules.",Nuclear magnetic resonance spectroscopy|NMR,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3061,Documentation and help,Documentation|Help,"Topic concerning the documentation of resources such as tools, services and databases and how to get help.",false,,,http://edamontology.org/topic_3068,beta13,,,,,,,,,edamontology:topic_3061,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the documentation of resources such as tools, services and databases and how to get help.",,Documentation|Help,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3367,Material science,Materials engineering,Topic concerning the discovery and design of new materials.,false,,,http://www.w3.org/2002/07/owl#Thing,1.4,,,,,,,,,edamontology:topic_3367,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the discovery and design of new materials.,Materials engineering,,,,http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_1775,Function analysis,Protein function prediction|Protein function analysis,Topic concerning the study of gene and protein function including the prediction of functional properties of a protein.,false,,,http://edamontology.org/topic_3307,beta12orEarlier,,,,,,,,,edamontology:topic_1775,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Function Prediction,Topic concerning the study of gene and protein function including the prediction of functional properties of a protein.,,Protein function prediction|Protein function analysis,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3298,Phenomics,,"Topic concerning phenomes, or the study of the change in phenotype (the physical and biochemical traits of organisms) in response to genetic and environmental factors. ",false,,,http://edamontology.org/topic_0625|http://edamontology.org/topic_3299,1.3,,,,,,,,,edamontology:topic_3298,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning phenomes, or the study of the change in phenotype (the physical and biochemical traits of organisms) in response to genetic and environmental factors. ",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0782,Fungi,Mycology,"The resource may be specific to a fungus, a group of fungi or all fungi.|Topic concerning fungi and molds, e.g. information on a specific fungal genome including molecular sequences, genes and annotation.",false,,,http://edamontology.org/topic_2818,beta12orEarlier,,,,,,,,,edamontology:topic_0782,,,,,,,,,,,,,,,,,,topic,,,,,,,,Mycology,,"Topic concerning fungi and molds, e.g. information on a specific fungal genome including molecular sequences, genes and annotation.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0097,Nucleic acid structure analysis,RNA structure alignment|DNA melting|RNA structure|Nucleic acid denaturation|RNA alignment|Nucleic acid thermodynamics|Nucleic acid structure,"Includes secondary and tertiary nucleic acid structural data, nucleic acid thermodynamic, thermal and conformational properties including DNA or DNA/RNA denaturation (melting) etc.|Topic concerning the archival, curation, processing and analysis of nucleic acid structural information, such as whole structures, structural features and alignments, and associated annotation.",false,,,http://edamontology.org/topic_0081,beta12orEarlier,,,,,,,,,edamontology:topic_0097,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the archival, curation, processing and analysis of nucleic acid structural information, such as whole structures, structural features and alignments, and associated annotation.",Nucleic acid structure,RNA structure alignment|DNA melting|RNA structure|Nucleic acid denaturation|RNA alignment|Nucleic acid thermodynamics,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3388,Molecular medicine,,Topic concerning the identification of molecular and genetic causes of disease and the development of interventions to correct them.,false,,,http://edamontology.org/topic_3342,1.4,,,,,,,,,edamontology:topic_3388,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the identification of molecular and genetic causes of disease and the development of interventions to correct them.,,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3332,Computational chemistry,,,false,,,http://edamontology.org/topic_3314|http://edamontology.org/topic_3316,1.3,,,,,,,,,edamontology:topic_3332,,,,,,,,,,,,,,,,,,topic,,,,,,,,,"Topic concerning the development and application of theory, analytical methods, mathematical models and computational simulation of chemical systems.",,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3302,Parasitology,,"Topic concerning the branch of medicine that deals with the anatomy, functions and disorders of the nervous system.|Topic concerning the biology of parasites.",false,,,http://edamontology.org/topic_3344,1.3,,,,,,,,,edamontology:topic_3302,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the branch of medicine that deals with the anatomy, functions and disorders of the nervous system.|Topic concerning the biology of parasites.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_2640,Oncology,Cancer|Cancer biology,"Topic concerning the study of cancer, for example, genes and proteins implicated in cancer.",false,,,http://edamontology.org/topic_3303,beta12orEarlier,,,,,,,,,edamontology:topic_2640,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the study of cancer, for example, genes and proteins implicated in cancer.",Cancer biology,Cancer,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0659,"Functional, regulatory and non-coding RNA",Non-coding RNA|Regulatory RNA|Functional RNA,"Non-coding RNA includes  piwi-interacting RNA (piRNA), small nuclear RNA (snRNA) and small nucleolar RNA (snoRNA).  Regulatory RNA includes microRNA (miRNA) - short single stranded RNA molecules that regulate gene expression, and small interfering RNA (siRNA).|Topic concerning non-coding or functional RNA sequences, including regulatory RNA sequences, ribosomal RNA (rRNA) and transfer RNA (tRNA).",false,,,http://edamontology.org/topic_0099,beta12orEarlier,,,,,,,,,edamontology:topic_0659,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning non-coding or functional RNA sequences, including regulatory RNA sequences, ribosomal RNA (rRNA) and transfer RNA (tRNA).",,Non-coding RNA|Regulatory RNA|Functional RNA,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0128,Protein interactions,Protein-DNA interaction|Protein-RNA interaction|Protein-protein interactions|Protein-ligand interactions|Protein-nucleic acid interactions,"This includes experimental (e.g. yeast two-hybrid) and computational analysis techniques.|Topic concerning protein-protein, protein-DNA/RNA and protein-ligand interactions, including analysis of known interactions and prediction of putative interactions.",false,,,http://edamontology.org/topic_0602|http://edamontology.org/topic_0078,beta12orEarlier,,,,,,,,,edamontology:topic_0128,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Protein Interaction|BioCatalogue:Ligand Interaction,"Topic concerning protein-protein, protein-DNA/RNA and protein-ligand interactions, including analysis of known interactions and prediction of putative interactions.",,Protein-DNA interaction|Protein-RNA interaction|Protein-protein interactions|Protein-ligand interactions|Protein-nucleic acid interactions,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3374,Drug formulation and delivery,Drug formulation|Drug delivery,Topic concerning the process of formulating abd administering a pharmaceutical compound to achieve a therapeutic effect.,false,,,http://edamontology.org/topic_3376,1.4,,,,,,,,,edamontology:topic_3374,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the process of formulating abd administering a pharmaceutical compound to achieve a therapeutic effect.,,Drug formulation|Drug delivery,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3381,Health economics,,"Topic concerning the branch of economics concerned with issues related to efficiency, effectiveness, value and behaviour in the production and consumption of health care.",false,,,http://edamontology.org/topic_3426,1.4,,,,,,,,,edamontology:topic_3381,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the branch of economics concerned with issues related to efficiency, effectiveness, value and behaviour in the production and consumption of health care.",,,,,http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3343,Compound libraries and screening,Chemical screening|Compound library|Chemical library|Translational medicine,"Topic concerning collections of chemicals, typically for use in high-throughput screening experiments.",false,,,http://edamontology.org/topic_3336,1.3,,,,,,,,,edamontology:topic_3343,,,,,,,,,,,,,,,,,,topic,,,,,,,,Translational medicine,,"Topic concerning collections of chemicals, typically for use in high-throughput screening experiments.",,Chemical screening|Compound library|Chemical library,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3068,Literature and reference,Literature search|Literature sources|http://purl.bioontology.org/ontology/MSH/D011642,"Topic concerning the scientific literature, reference information and documentation.",false,,,http://www.w3.org/2002/07/owl#Thing,beta13,,,,,,,,,edamontology:topic_3068,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the scientific literature, reference information and documentation.",,Literature search|Literature sources,http://purl.bioontology.org/ontology/MSH/D011642,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3377,Safety sciences,Drug safety,Topic concerning the safety (or lack) of drugs and other medical interventions.,false,,,http://edamontology.org/topic_3376,1.4,,,,,,,,,edamontology:topic_3377,,,,,,,,,,,,,,,,,,,,,,,,,,,,Topic concerning the safety (or lack) of drugs and other medical interventions.,,Drug safety,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3342,Translational medicine,,"Topic concerning 'translating' the output of basic and biomedical research into better diagnostic tools, medicines, medical procedures, policies and advice.",false,,,http://edamontology.org/topic_3303,1.3,,,,,,,,,edamontology:topic_3342,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning 'translating' the output of basic and biomedical research into better diagnostic tools, medicines, medical procedures, policies and advice.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0084,Phylogeny,http://purl.bioontology.org/ontology/MSH/D010802|Phylogeny reconstruction|Phylogenetic clocks|Phylogenetic simulation|Phylogenetic stratigraphy|Phylogenetic dating,"This includes diverse phylogenetic methods, including phylogenetic tree construction, typically from molecular sequence or morphological data, methods that simulate DNA sequence evolution, a phylogenetic tree or the underlying data, or which estimate or use molecular clock and stratigraphic (age) data, methods for studying gene evolution etc.|Topic concerning the study of evolutionary relationships amongst organisms.",false,,,http://edamontology.org/topic_3299,beta12orEarlier,,,,,,,,,edamontology:topic_0084,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Tree Inference|BioCatalogue:Phylogeny|BioCatalogue:Statistical Robustness|BioCatalogue:Evolutionary Distance Measurements,Topic concerning the study of evolutionary relationships amongst organisms.,,http://purl.bioontology.org/ontology/MSH/D010802|Phylogeny reconstruction|Phylogenetic clocks|Phylogenetic simulation|Phylogenetic stratigraphy|Phylogenetic dating,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0781,Viruses,Virology,"The resource may be specific to a virus, a group of viruses or all viruses.|Topic concerning viruses, e.g. sequence and structural data, interactions of viral proteins, or a viral genome including molecular sequences, genes and annotation.",false,,,http://edamontology.org/topic_0621,beta12orEarlier,,,,,,,,,edamontology:topic_0781,,,,,,,,,,,,,,,,,,topic,,,,,,,,Virology,,"Topic concerning viruses, e.g. sequence and structural data, interactions of viral proteins, or a viral genome including molecular sequences, genes and annotation.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_2821,Unicellular eukaryotes,,"The resource may be specific to a unicellular eukaryote, a group of unicellular eukaryotes or all unicellular eukaryotes.|Topic concerning unicellular eukaryotes, e.g. information on a unicellular eukaryote genome including molecular sequences, genes and annotation.",false,,,http://edamontology.org/topic_2818,beta12orEarlier,,,,,,,,,edamontology:topic_2821,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning unicellular eukaryotes, e.g. information on a unicellular eukaryote genome including molecular sequences, genes and annotation.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3340,Cell culture collection,,"Topic concerning collections of cells grown under laboratory conditions, specifically, cells from multi-cellular eukaryotes and especially animal cells.",false,,,http://edamontology.org/topic_3277,1.3,,,,,,,,,edamontology:topic_3340,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning collections of cells grown under laboratory conditions, specifically, cells from multi-cellular eukaryotes and especially animal cells.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3378,Pharmacovigilence,,"Pharmacovigilence concerns safety once a drug has gone to market.|Topic concerning the detection, assesment, understanding and prevention of adverse effects of medicines.",false,,,http://edamontology.org/topic_3377,1.4,,,,,,,,,edamontology:topic_3378,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the detection, assesment, understanding and prevention of adverse effects of medicines.",,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_2844,Structural clustering,Structure classification,"Topic concerning the comparison and grouping together of molecular structures on the basis of similarity; generate, process or analyse structural clusters.",false,,,http://edamontology.org/topic_1770,beta12orEarlier,,,,,,,,,edamontology:topic_2844,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the comparison and grouping together of molecular structures on the basis of similarity; generate, process or analyse structural clusters.",Structure classification,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3422,Urology and nephrology,Urological disorders|Kidney disease|Nephrology|Urology,"Topic concerning the branches of medicine and physiology focussing on the function and disorders of the urinary system in males and females, the reproductive system in males, and the kidney.",false,,,http://edamontology.org/topic_3303,1.4,,,,,,,,,edamontology:topic_3422,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the branches of medicine and physiology focussing on the function and disorders of the urinary system in males and females, the reproductive system in males, and the kidney.",,Urological disorders|Kidney disease|Nephrology|Urology,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3427,Research study design,,"Topic concerning the process used to define a scientific study type and subtype, research question, hypotheses, independet and dependent variables, experimental design and, if applicable, data collection methods, statistical analysis plan and data management plan.",false,,,http://edamontology.org/topic_3364,1.4,,,,,,,,,edamontology:topic_3427,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the process used to define a scientific study type and subtype, research question, hypotheses, independet and dependent variables, experimental design and, if applicable, data collection methods, statistical analysis plan and data management plan.",,,,,http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3318,Physics,,"Topic concerning the study of matter, space and time, and related concepts such as energy and force.",false,,,http://www.w3.org/2002/07/owl#Thing,1.3,,,,,,,,,edamontology:topic_3318,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the study of matter, space and time, and related concepts such as energy and force.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3299,Evolutionary biology,,"Topic concerning the evolutionary processes, from the genetic to environmental scale, that produced life in all its diversity.",false,,,http://edamontology.org/topic_3070,1.3,,,,,,,,,edamontology:topic_3299,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the evolutionary processes, from the genetic to environmental scale, that produced life in all its diversity.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3050,Biodiversity,http://purl.bioontology.org/ontology/MSH/D044822,"Topic concerning the degree of variation of life forms within a given ecosystem, biome or an entire planet.",false,,,http://edamontology.org/topic_0610,beta13,,,,,,,,,edamontology:topic_3050,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the degree of variation of life forms within a given ecosystem, biome or an entire planet.",http://purl.bioontology.org/ontology/MSH/D044822,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3067,Anatomy,,Topic concerning the form and function of the structures of living organisms.,false,,,http://edamontology.org/topic_3344,beta13,,,,,,,,,edamontology:topic_3067,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,Topic concerning the form and function of the structures of living organisms.,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3417,Opthalmology,Eye disoders|Audiovestibular medicine,"Topic concerning the branch of medicine that deals with disorders of the eye, including eyelid, optic nerve/visual pathways and occular muscles.",false,,,http://edamontology.org/topic_3303,1.4,,,,,,,,,edamontology:topic_3417,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the branch of medicine that deals with disorders of the eye, including eyelid, optic nerve/visual pathways and occular muscles.",Audiovestibular medicine,Eye disoders,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3368,Biomaterials,Diagnostic markers,"Topic concerning any matter, surface or construct that interacts with a biological system.",false,,,http://edamontology.org/topic_3297,1.4,,,,,,,,,edamontology:topic_3368,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning any matter, surface or construct that interacts with a biological system.",Diagnostic markers,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_2277,SNPs,,"A SNP is a DNA sequence variation where a single nucleotide differs between members of a species or paired chromosomes in an individual.|Topic concerning single nucleotide polymorphisms (SNP) and associated data, for example, the discovery and annotation of SNPs.",false,,,http://edamontology.org/topic_0199,beta12orEarlier,,,,,,,,,edamontology:topic_2277,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning single nucleotide polymorphisms (SNP) and associated data, for example, the discovery and annotation of SNPs.",,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0620,Drugs and target structures,Drug structures|Target structures,"Topic concerning the structures of drugs, drug target, their interactions and binding affinities.",false,,,http://edamontology.org/topic_3336|http://edamontology.org/topic_0154,beta12orEarlier,,,,,,,,,edamontology:topic_0620,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning the structures of drugs, drug target, their interactions and binding affinities.",,Drug structures|Target structures,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_3394,Regulatory affairs,,"Topic concerning the protection of public health by controlling the safety and efficacy of products in areas including pharmaceuticals, veterinary medicine, medical devices, pesticides, agrochemicals, cosmetics, and complementary medicines.",false,,,http://edamontology.org/topic_3376,1.4,,,,,,,,,edamontology:topic_3394,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Topic concerning the protection of public health by controlling the safety and efficacy of products in areas including pharmaceuticals, veterinary medicine, medical devices, pesticides, agrochemicals, cosmetics, and complementary medicines.",,,,,http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0203,Gene expression,DNA microarrays|Codon usage|Gene expression profiling|Expression profiling|http://purl.bioontology.org/ontology/MSH/D015870|Gene expression analysis,"Gene expression levels are analysed by identifying, quantifying or comparing mRNA transcripts, for example using microarrays, RNA-seq, northern blots, gene-indexed expression profiles etc.|Topic concerning the analysis of levels and patterns of synthesis of gene products (proteins and functional RNA) including interpretation in functional terms of gene expression data.",false,,,http://edamontology.org/topic_3053,beta12orEarlier,,,,,,,,,edamontology:topic_0203,,,,,,,,,,,,,,,,,,topic,,,,,,,http://edamontology.org/topic_0197,,BioCatalogue:Microarrays,Topic concerning the analysis of levels and patterns of synthesis of gene products (proteins and functional RNA) including interpretation in functional terms of gene expression data.,Gene expression analysis,DNA microarrays|Codon usage|Gene expression profiling|Expression profiling,http://purl.bioontology.org/ontology/MSH/D015870,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0159,Sequence comparison,,"The comparison might be on the basis of sequence, physico-chemical or some other properties of the sequences.|Topic concerning the comparison of two or more molecular sequences.",false,,,http://edamontology.org/topic_0080,beta12orEarlier,,,,,,,,,edamontology:topic_0159,,,,,,,,,,,,,,,,,,topic,,,,,,,,,BioCatalogue:Protein Sequence Similarity|BioCatalogue:Nucleotide Sequence Similarity,Topic concerning the comparison of two or more molecular sequences.,,,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
http://edamontology.org/topic_0621,Organisms,Model organisms,"This may include information on the genome (including molecular sequences and map, genes and annotation), proteome, as well as more general information about an organism.|Topic concerning a specific organism, or group of organisms, used to study a particular aspect of biology.",false,,,http://edamontology.org/topic_3070,beta12orEarlier,,,,,,,,,edamontology:topic_0621,,,,,,,,,,,,,,,,,,topic,,,,,,,,,,"Topic concerning a specific organism, or group of organisms, used to study a particular aspect of biology.",,Model organisms,,,http://purl.obolibrary.org/obo/edam#bioinformatics|http://purl.obolibrary.org/obo/edam#edam|http://purl.obolibrary.org/obo/edam#events|http://purl.obolibrary.org/obo/edam#topics,,,,,,,,,,,,,
