{"id":"http://purl.obolibrary.org/obo/CHEBI_4907","prefLabel":"etidronic acid","synonym":["(1-hydroxyethane-1,1-diyl)bis(phosphonic acid)","Oxyethylidenediphosphonic acid","etidronic acid","1-Hydroxyethylidene-1,1-bisphosphonate","acido etidronico","1-Hydroxyethane-1,1-bisphosphonic acid","(1-Hydroxyethylidene)bis(phosphonic acid)","(1-Hydroxyethylidene)bisphosphonic acid","Acetodiphosphonic acid","etidronate","1-Hydroxyethane-1,1-diphosphonic acid","1-Hydroxyethane-1,1-diphosphonate","1-Hydroxy-1,1-diphosphonoethane","HEDP","(1-Hydroxyethylidene)diphosphonic acid","Etidronsaeure","1-Hydroxyethylidene-1,1-diphosphonic acid","Ethane-1-hydroxy-1,1-diphosphonic acid","EHDP","(1-Hydroxyethylene)diphosphonic acid","Hydroxyethanediphosphonic acid","(Hydroxyethylidene)diphosphonic acid","acidum etidronicum","Ethane-1-hydroxy-1,1-diphosphonate","acide etidronique","1-Hydroxyethanediphosphonic acid","ethane-1-hydroxy-1,1-bisphosphonic acid","1,1,1-Ethanetriol diphosphonate"],"definition":["A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces."],"notation":"CHEBI:4907","xref":"pubmed:11503828","parents":[{"id":"http://purl.obolibrary.org/obo/CHEBI_50860","prefLabel":"organic molecular entity","definition":["Any molecular entity that contains carbon."],"synonym":["organic compounds","organic entity","organic molecular entities"],"notation":"CHEBI:50860","label":["organic molecular entity"],"subClassOf":["http://purl.obolibrary.org/obo/CHEBI_33582"],"prefLabelXl":[],"altLabelXl":[],"hiddenLabelXl":[],"obsolete":false,"prefixIRI":null,"semanticType":[],"cui":[],"xref":null,"inScheme":[],"created":null,"modified":null,"@id":"http://purl.obolibrary.org/obo/CHEBI_50860","@type":"http://www.w3.org/2002/07/owl#Class","links":{"self":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_50860","ontology":"https://data.bioontology.org/ontologies/CHEBI","children":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_50860/children","parents":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_50860/parents","descendants":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_50860/descendants","ancestors":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_50860/ancestors","instances":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_50860/instances","tree":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_50860/tree","notes":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_50860/notes","mappings":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_50860/mappings","ui":"http://bioportal.bioontology.org/ontologies/CHEBI?p=classes&conceptid=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_50860","@context":{"self":"http://www.w3.org/2002/07/owl#Class","ontology":"http://data.bioontology.org/metadata/Ontology","children":"http://www.w3.org/2002/07/owl#Class","parents":"http://www.w3.org/2002/07/owl#Class","descendants":"http://www.w3.org/2002/07/owl#Class","ancestors":"http://www.w3.org/2002/07/owl#Class","instances":"http://data.bioontology.org/metadata/Instance","tree":"http://www.w3.org/2002/07/owl#Class","notes":"http://data.bioontology.org/metadata/Note","mappings":"http://data.bioontology.org/metadata/Mapping","ui":"http://www.w3.org/2002/07/owl#Class"}},"@context":{"@vocab":"http://data.bioontology.org/metadata/","label":"http://www.w3.org/2000/01/rdf-schema#label","prefLabel":"http://www.w3.org/2004/02/skos/core#prefLabel","prefLabelXl":"http://www.w3.org/2008/05/skos-xl#prefLabel","altLabelXl":"http://www.w3.org/2008/05/skos-xl#altLabel","hiddenLabelXl":"http://www.w3.org/2008/05/skos-xl#hiddenLabel","synonym":"http://www.w3.org/2004/02/skos/core#altLabel","definition":"http://www.w3.org/2004/02/skos/core#definition","obsolete":"http://www.w3.org/2002/07/owl#deprecated","notation":"http://www.w3.org/2004/02/skos/core#notation","prefixIRI":"http://data.bioontology.org/metadata/prefixIRI","subClassOf":"http://www.w3.org/2000/01/rdf-schema#subClassOf","semanticType":"http://bioportal.bioontology.org/ontologies/umls/hasSTY","cui":"http://bioportal.bioontology.org/ontologies/umls/cui","xref":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","inScheme":"http://www.w3.org/2004/02/skos/core#inScheme","created":"http://purl.org/dc/terms/created","modified":"http://purl.org/dc/terms/modified","@language":[]}},{"id":"http://purl.obolibrary.org/obo/CHEBI_77383","prefLabel":"1,1-bis(phosphonic acid)","definition":["Any member of the class of phosphonic acids in which a carbon atom is directly attached to two phosphonic acid groups. They are analogues of pyrophosphates (with the central oxygen atom replaced by a carbon atom) and like pyrophosphates they tend to have a strong affinity for bone, so are frequently used for their antiresorptive and hypocalcaemic properties."],"synonym":["1,1-diphosphonic acids","bis(phosphonic acid)","diphosphonic acid","bisphosphonates","1,1-diphosphonate","1,1-bis(phosphonic acid)s","1,1-diphosphonates","bisphosphonate","1,1-diphosphonic acid","bis(phosphonic acid)s"],"notation":"CHEBI:77383","xref":"wikipedia.en:Bisphosphonate","label":["1,1-bis(phosphonic acid)"],"subClassOf":["http://purl.obolibrary.org/obo/CHEBI_26069"],"prefLabelXl":[],"altLabelXl":[],"hiddenLabelXl":[],"obsolete":false,"prefixIRI":null,"semanticType":[],"cui":[],"inScheme":[],"created":null,"modified":null,"@id":"http://purl.obolibrary.org/obo/CHEBI_77383","@type":"http://www.w3.org/2002/07/owl#Class","links":{"self":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_77383","ontology":"https://data.bioontology.org/ontologies/CHEBI","children":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_77383/children","parents":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_77383/parents","descendants":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_77383/descendants","ancestors":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_77383/ancestors","instances":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_77383/instances","tree":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_77383/tree","notes":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_77383/notes","mappings":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_77383/mappings","ui":"http://bioportal.bioontology.org/ontologies/CHEBI?p=classes&conceptid=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_77383","@context":{"self":"http://www.w3.org/2002/07/owl#Class","ontology":"http://data.bioontology.org/metadata/Ontology","children":"http://www.w3.org/2002/07/owl#Class","parents":"http://www.w3.org/2002/07/owl#Class","descendants":"http://www.w3.org/2002/07/owl#Class","ancestors":"http://www.w3.org/2002/07/owl#Class","instances":"http://data.bioontology.org/metadata/Instance","tree":"http://www.w3.org/2002/07/owl#Class","notes":"http://data.bioontology.org/metadata/Note","mappings":"http://data.bioontology.org/metadata/Mapping","ui":"http://www.w3.org/2002/07/owl#Class"}},"@context":{"@vocab":"http://data.bioontology.org/metadata/","label":"http://www.w3.org/2000/01/rdf-schema#label","prefLabel":"http://www.w3.org/2004/02/skos/core#prefLabel","prefLabelXl":"http://www.w3.org/2008/05/skos-xl#prefLabel","altLabelXl":"http://www.w3.org/2008/05/skos-xl#altLabel","hiddenLabelXl":"http://www.w3.org/2008/05/skos-xl#hiddenLabel","synonym":"http://www.w3.org/2004/02/skos/core#altLabel","definition":"http://www.w3.org/2004/02/skos/core#definition","obsolete":"http://www.w3.org/2002/07/owl#deprecated","notation":"http://www.w3.org/2004/02/skos/core#notation","prefixIRI":"http://data.bioontology.org/metadata/prefixIRI","subClassOf":"http://www.w3.org/2000/01/rdf-schema#subClassOf","semanticType":"http://bioportal.bioontology.org/ontologies/umls/hasSTY","cui":"http://bioportal.bioontology.org/ontologies/umls/cui","xref":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","inScheme":"http://www.w3.org/2004/02/skos/core#inScheme","created":"http://purl.org/dc/terms/created","modified":"http://purl.org/dc/terms/modified","@language":[]}}],"label":["etidronic acid"],"subClassOf":["http://purl.obolibrary.org/obo/CHEBI_50860","http://purl.obolibrary.org/obo/CHEBI_77383"],"obsolete":false,"prefixIRI":null,"semanticType":[],"cui":[],"inScheme":[],"created":null,"modified":null,"memberOf":[],"altLabelXl":[],"hiddenLabelXl":[],"prefLabelXl":[],"isInActiveScheme":[null],"isInActiveCollection":[],"properties":{"http://www.geneontology.org/formats/oboInOwl#hasExactSynonym":["(1-hydroxyethane-1,1-diyl)bis(phosphonic acid)"],"https://data.bioontology.org/metadata/def/prefLabel":["etidronic acid"],"http://www.geneontology.org/formats/oboInOwl#hasOBONamespace":["chebi_ontology"],"http://purl.obolibrary.org/obo/IAO_0000115":["A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces."],"http://www.w3.org/1999/02/22-rdf-syntax-ns#type":["http://www.w3.org/2002/07/owl#Class"],"http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym":["Oxyethylidenediphosphonic acid","etidronic acid","1-Hydroxyethylidene-1,1-bisphosphonate","(1-hydroxyethane-1,1-diyl)bis(phosphonic acid)","acido etidronico","1-Hydroxyethane-1,1-bisphosphonic acid","(1-Hydroxyethylidene)bis(phosphonic acid)","(1-Hydroxyethylidene)bisphosphonic acid","Acetodiphosphonic acid","etidronate","1-Hydroxyethane-1,1-diphosphonic acid","1-Hydroxyethane-1,1-diphosphonate","1-Hydroxy-1,1-diphosphonoethane","HEDP","(1-Hydroxyethylidene)diphosphonic acid","Etidronsaeure","1-Hydroxyethylidene-1,1-diphosphonic acid","Ethane-1-hydroxy-1,1-diphosphonic acid","EHDP","(1-Hydroxyethylene)diphosphonic acid","Hydroxyethanediphosphonic acid","(Hydroxyethylidene)diphosphonic acid","acidum etidronicum","Ethane-1-hydroxy-1,1-diphosphonate","acide etidronique","1-Hydroxyethanediphosphonic acid","ethane-1-hydroxy-1,1-bisphosphonic acid","1,1,1-Ethanetriol diphosphonate"],"http://www.geneontology.org/formats/oboInOwl#id":["CHEBI:4907"],"http://www.geneontology.org/formats/oboInOwl#hasAlternativeId":["CHEBI:63588"],"http://purl.obolibrary.org/obo/chemrof#_generalized_empirical_formula":["C2H8O7P2"],"http://www.geneontology.org/formats/oboInOwl#inSubset":["http://purl.obolibrary.org/obo/3_STAR"],"http://purl.obolibrary.org/obo/chemrof#_monoisotopic_mass":["205.97453"],"http://purl.obolibrary.org/obo/RO_0018034":["http://purl.obolibrary.org/obo/CHEBI_77356"],"http://www.w3.org/2004/02/skos/core#notation":["CHEBI:4907"],"http://purl.obolibrary.org/obo/chemrof#_inchi_string":["InChI=1S/C2H8O7P2/c1-2(3,10(4,5)6)11(7,8)9/h3H,1H3,(H2,4,5,6)(H2,7,8,9)"],"http://purl.obolibrary.org/obo/RO_0000087":["http://purl.obolibrary.org/obo/CHEBI_35610","http://purl.obolibrary.org/obo/CHEBI_50646","http://purl.obolibrary.org/obo/CHEBI_38161"],"http://purl.obolibrary.org/obo/chemrof_charge":["0"],"http://purl.obolibrary.org/obo/chemrof#_inchi_key_string":["DBVJJBKOTRCVKF-UHFFFAOYSA-N"],"http://www.geneontology.org/formats/oboInOwl#hasDbXref":["pubmed:11503828","drugbank:DB01077","pubmed:7858370","lincs.smallmolecule:LSM-5508","wikipedia.en:Etidronic_acid","patent:US3400147","cas:2809-21-4","pubmed:18646327","pubmed:17214981","hmdb:HMDB0015210","pdb-ccd:911","patent:US3468935","pubmed:10385693","drugcentral:1098","patent:US3475486","pubmed:17157266","kegg.drug:D02373","pubmed:22515905","reaxys:1789291","kegg.compound:C07736","patent:US3159581","pubmed:18313802"],"http://purl.obolibrary.org/obo/chemrof_mass":["206.027"],"http://purl.obolibrary.org/obo/chemrof#_smiles_string":["CC(O)(P(=O)(O)O)P(=O)(O)O"],"https://data.bioontology.org/metadata/treeView":["http://purl.obolibrary.org/obo/CHEBI_50860","http://purl.obolibrary.org/obo/CHEBI_77383"],"http://www.w3.org/2000/01/rdf-schema#label":["etidronic acid"],"http://www.w3.org/2000/01/rdf-schema#subClassOf":["http://purl.obolibrary.org/obo/CHEBI_50860","http://purl.obolibrary.org/obo/CHEBI_77383"]},"@id":"http://purl.obolibrary.org/obo/CHEBI_4907","@type":"http://www.w3.org/2002/07/owl#Class","links":{"self":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_4907","ontology":"https://data.bioontology.org/ontologies/CHEBI","children":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_4907/children","parents":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_4907/parents","descendants":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_4907/descendants","ancestors":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_4907/ancestors","instances":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_4907/instances","tree":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_4907/tree","notes":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_4907/notes","mappings":"https://data.bioontology.org/ontologies/CHEBI/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_4907/mappings","ui":"http://bioportal.bioontology.org/ontologies/CHEBI?p=classes&conceptid=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_4907","@context":{"self":"http://www.w3.org/2002/07/owl#Class","ontology":"http://data.bioontology.org/metadata/Ontology","children":"http://www.w3.org/2002/07/owl#Class","parents":"http://www.w3.org/2002/07/owl#Class","descendants":"http://www.w3.org/2002/07/owl#Class","ancestors":"http://www.w3.org/2002/07/owl#Class","instances":"http://data.bioontology.org/metadata/Instance","tree":"http://www.w3.org/2002/07/owl#Class","notes":"http://data.bioontology.org/metadata/Note","mappings":"http://data.bioontology.org/metadata/Mapping","ui":"http://www.w3.org/2002/07/owl#Class"}},"@context":{"@vocab":"http://data.bioontology.org/metadata/","label":"http://www.w3.org/2000/01/rdf-schema#label","prefLabel":"http://www.w3.org/2004/02/skos/core#prefLabel","prefLabelXl":"http://www.w3.org/2008/05/skos-xl#prefLabel","altLabelXl":"http://www.w3.org/2008/05/skos-xl#altLabel","hiddenLabelXl":"http://www.w3.org/2008/05/skos-xl#hiddenLabel","synonym":"http://www.w3.org/2004/02/skos/core#altLabel","definition":"http://www.w3.org/2004/02/skos/core#definition","obsolete":"http://www.w3.org/2002/07/owl#deprecated","notation":"http://www.w3.org/2004/02/skos/core#notation","prefixIRI":"http://data.bioontology.org/metadata/prefixIRI","parents":"http://www.w3.org/2000/01/rdf-schema##","subClassOf":"http://www.w3.org/2000/01/rdf-schema#subClassOf","semanticType":"http://bioportal.bioontology.org/ontologies/umls/hasSTY","cui":"http://bioportal.bioontology.org/ontologies/umls/cui","xref":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","inScheme":"http://www.w3.org/2004/02/skos/core#inScheme","created":"http://purl.org/dc/terms/created","modified":"http://purl.org/dc/terms/modified","@language":[]}}