2 34 0 http://purl.obolibrary.org/obo/DIDEO_00000059 evidence information from transport protein identification experiment 'evidence information from transport protein identification experiment' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some ('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some http://purl.obolibrary.org/obo/OBI_0001211)) and (http://purl.obolibrary.org/obo/OBI_0000293 some ('chemical substance' and ('is_specified_output_of' some (http://purl.obolibrary.org/obo/GO_0098739 and ('has participant' some 'protein') and ('has participant' some ('chemical substance' and ('part of' some 'drug product'))))))))) http://purl.obolibrary.org/obo/DIDEO_00000060 evidence information from transport protein inhibition experiment 'evidence information from transport protein inhibition experiment' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some ('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some http://purl.obolibrary.org/obo/OBI_0001211)) and (http://purl.obolibrary.org/obo/OBI_0000293 some ('chemical substance' and ('is_specified_output_of' some (http://purl.obolibrary.org/obo/GO_0032410 and ('has participant' some 'protein') and ('has participant' some ('chemical substance' and ('part of' some 'drug product'))))))))) http://purl.obolibrary.org/obo/GO_0098657 import into cell 'import into cell' SubClassOf 'transport' http://purl.obolibrary.org/obo/DIDEO_00000104 evidence information from p-glycoprotein transport protein identification experiment 'evidence information from p-glycoprotein transport protein identification experiment' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some ('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some ('chemical substance' and ('is_specified_output_of' some ('import across plasma membrane' and ('has participant' some 'multidrug resistance protein 1') and ('has participant' some ('chemical substance' and ('part of' some 'drug product'))))))))) 'evidence information from p-glycoprotein transport protein identification experiment' SubClassOf 'evidence information content entity' http://purl.obolibrary.org/obo/DIDEO_00000105 evidence information from p-glycoprotein transport protein identification experiment using Caco 2 cell lines 'evidence information from p-glycoprotein transport protein identification experiment using Caco 2 cell lines' SubClassOf 'evidence information content entity' 'evidence information from p-glycoprotein transport protein identification experiment using Caco 2 cell lines' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some ('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some 'Caco-2 cell') and (http://purl.obolibrary.org/obo/OBI_0000293 some ('chemical substance' and ('is_specified_output_of' some ('import across plasma membrane' and ('has participant' some 'multidrug resistance protein 1') and ('has participant' some ('chemical substance' and ('part of' some 'drug product'))))))))) http://purl.obolibrary.org/obo/DIDEO_00000106 evidence information from p-glycoprotein transport protein identification experiment using overexpressed cell lines 'evidence information from p-glycoprotein transport protein identification experiment using overexpressed cell lines' SubClassOf 'evidence information content entity' 'evidence information from p-glycoprotein transport protein identification experiment using overexpressed cell lines' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some ('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some ('chemical substance' and ('is_specified_output_of' some ('import across plasma membrane' and ('has participant' some 'multidrug resistance protein 1') and ('has participant' some ('chemical substance' and ('part of' some 'drug product'))))))) and (http://purl.obolibrary.org/obo/OBI_0000293 some ('cell line cell' and ('participates in' some 'overexpression'))))) http://purl.obolibrary.org/obo/DIDEO_00000107 evidence information from OATP1B1 transport protein identification experiment 'evidence information from OATP1B1 transport protein identification experiment' SubClassOf 'evidence information content entity' 'evidence information from OATP1B1 transport protein identification experiment' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some ('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some ('chemical substance' and ('is_specified_output_of' some ('import across plasma membrane' and ('has participant' some 'solute carrier organic anion transporter family member 1B1') and ('has participant' some ('chemical substance' and ('part of' some 'drug product'))))))))) http://purl.obolibrary.org/obo/CLO_0000001 cell line cell 'cell line cell' SubClassOf 'cultured cell' http://purl.obolibrary.org/obo/DIDEO_00000110 evidence information from OATP1B3 transport protein identification experiment using overexpressed cell lines 'evidence information from OATP1B3 transport protein identification experiment using overexpressed cell lines' SubClassOf 'evidence information content entity' 'evidence information from OATP1B3 transport protein identification experiment using overexpressed cell lines' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some ('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some ('chemical substance' and ('is_specified_output_of' some ('import across plasma membrane' and ('has participant' some 'solute carrier organic anion transporter family member 1B3') and ('has participant' some ('chemical substance' and ('part of' some 'drug product'))))))) and (http://purl.obolibrary.org/obo/OBI_0000293 some ('cell line cell' and ('participates in' some 'overexpression'))))) http://purl.obolibrary.org/obo/DIDEO_00000115 evidence information from OATP1B1 inhibition experiment using overexpressed cell lines 'evidence information from OATP1B1 inhibition experiment using overexpressed cell lines' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some ('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some ('chemical substance' and ('is_specified_output_of' some ('negative regulation of transporter activity' and ('has participant' some 'solute carrier organic anion transporter family member 1B1') and ('has participant' some ('chemical substance' and ('part of' some 'drug product'))))))) and (http://purl.obolibrary.org/obo/OBI_0000293 some ('cell line cell' and ('participates in' some 'overexpression'))))) 'evidence information from OATP1B1 inhibition experiment using overexpressed cell lines' SubClassOf 'evidence information content entity' http://purl.obolibrary.org/obo/DIDEO_00000116 evidence information from OATP1B3 inhibition experiment using overexpressed cell lines 'evidence information from OATP1B3 inhibition experiment using overexpressed cell lines' SubClassOf 'evidence information content entity' 'evidence information from OATP1B3 inhibition experiment using overexpressed cell lines' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some ('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some ('chemical substance' and ('is_specified_output_of' some ('negative regulation of transporter activity' and ('has participant' some 'solute carrier organic anion transporter family member 1B3') and ('has participant' some ('chemical substance' and ('part of' some 'drug product'))))))) and (http://purl.obolibrary.org/obo/OBI_0000293 some ('cell line cell' and ('participates in' some 'overexpression'))))) http://purl.obolibrary.org/obo/DIDEO_00000117 evidence information from OATP1B3 inhibition experiment 'evidence information from OATP1B3 inhibition experiment' SubClassOf 'evidence information content entity' 'evidence information from OATP1B3 inhibition experiment' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some ('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some ('chemical substance' and ('is_specified_output_of' some ('negative regulation of transporter activity' and ('has participant' some 'solute carrier organic anion transporter family member 1B3') and ('has participant' some ('chemical substance' and ('part of' some 'drug product'))))))))) http://purl.obolibrary.org/obo/DIDEO_00000111 evidence information from p-glycoprotein inhibition experiment 'evidence information from p-glycoprotein inhibition experiment' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some ('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some ('chemical substance' and ('is_specified_output_of' some ('negative regulation of transporter activity' and ('has participant' some 'multidrug resistance protein 1') and ('has participant' some ('chemical substance' and ('part of' some 'drug product'))))))))) 'evidence information from p-glycoprotein inhibition experiment' SubClassOf 'evidence information content entity' http://purl.obolibrary.org/obo/DIDEO_00000112 evidence information from p-glycoprotein inhibition experiment using Caco 2 cell lines 'evidence information from p-glycoprotein inhibition experiment using Caco 2 cell lines' SubClassOf 'evidence information content entity' 'evidence information from p-glycoprotein inhibition experiment using Caco 2 cell lines' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some ('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some 'Caco-2 cell') and (http://purl.obolibrary.org/obo/OBI_0000293 some ('chemical substance' and ('is_specified_output_of' some ('negative regulation of transporter activity' and ('has participant' some 'multidrug resistance protein 1') and ('has participant' some ('chemical substance' and ('part of' some 'drug product'))))))))) http://purl.obolibrary.org/obo/DIDEO_00000113 evidence information from p-glycoprotein inhibition experiment using overexpressed cell lines 'evidence information from p-glycoprotein inhibition experiment using overexpressed cell lines' SubClassOf 'evidence information content entity' 'evidence information from p-glycoprotein inhibition experiment using overexpressed cell lines' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some ('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some ('chemical substance' and ('is_specified_output_of' some ('negative regulation of transporter activity' and ('has participant' some 'multidrug resistance protein 1') and ('has participant' some ('chemical substance' and ('part of' some 'drug product'))))))) and (http://purl.obolibrary.org/obo/OBI_0000293 some ('cell line cell' and ('participates in' some 'overexpression'))))) http://purl.obolibrary.org/obo/DIDEO_00000114 evidence information from OATP1B1 inhibition experiment 'evidence information from OATP1B1 inhibition experiment' SubClassOf 'evidence information content entity' 'evidence information from OATP1B1 inhibition experiment' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some ('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some ('chemical substance' and ('is_specified_output_of' some ('negative regulation of transporter activity' and ('has participant' some 'solute carrier organic anion transporter family member 1B1') and ('has participant' some ('chemical substance' and ('part of' some 'drug product'))))))))) http://purl.obolibrary.org/obo/DIDEO_00000108 evidence information from OATP1B3 transport protein identification experiment 'evidence information from OATP1B3 transport protein identification experiment' SubClassOf 'evidence information content entity' 'evidence information from OATP1B3 transport protein identification experiment' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some ('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some ('chemical substance' and ('is_specified_output_of' some ('import across plasma membrane' and ('has participant' some 'solute carrier organic anion transporter family member 1B3') and ('has participant' some ('chemical substance' and ('part of' some 'drug product'))))))))) http://purl.obolibrary.org/obo/DIDEO_00000109 evidence information from OATP1B1 transport protein identification experiment using overexpressed cell lines 'evidence information from OATP1B1 transport protein identification experiment using overexpressed cell lines' EquivalentTo 'evidence information content entity' and (http://purl.obolibrary.org/obo/IAO_0000136 some ('assay' and (http://purl.obolibrary.org/obo/BFO_0000055 some (http://purl.obolibrary.org/obo/RO_0000059 some 'ex vivo design')) and (http://purl.obolibrary.org/obo/OBI_0000293 some ('chemical substance' and ('is_specified_output_of' some ('import across plasma membrane' and ('has participant' some 'solute carrier organic anion transporter family member 1B1') and ('has participant' some ('chemical substance' and ('part of' some 'drug product'))))))) and (http://purl.obolibrary.org/obo/OBI_0000293 some ('cell line cell' and ('participates in' some 'overexpression'))))) 'evidence information from OATP1B1 transport protein identification experiment using overexpressed cell lines' SubClassOf 'evidence information content entity' http://purl.obolibrary.org/obo/GO_0051234 establishment of localization 'establishment of localization' SubClassOf 'localization' http://purl.obolibrary.org/obo/GO_0098739 import across plasma membrane 'import across plasma membrane' SubClassOf 'import into cell' http://purl.obolibrary.org/obo/INO_0000102 gene expression 'gene expression' SubClassOf 'biological_process' http://purl.obolibrary.org/obo/INO_0000114 overexpression 'overexpression' SubClassOf 'gene expression' http://purl.obolibrary.org/obo/GO_0032879 regulation of localization 'regulation of localization' SubClassOf 'regulation of biological process' http://purl.obolibrary.org/obo/GO_0051049 regulation of transport 'regulation of transport' SubClassOf 'regulation of localization' http://purl.obolibrary.org/obo/CL_0000578 experimentally modified cell in vitro 'experimentally modified cell in vitro' SubClassOf 'processed material' http://purl.obolibrary.org/obo/CLO_0002172 Caco-2 cell 'Caco-2 cell' SubClassOf 'cell line cell' http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport 'negative regulation of transport' SubClassOf 'regulation of transport' http://purl.obolibrary.org/obo/GO_0006810 transport 'transport' SubClassOf 'establishment of localization' http://purl.obolibrary.org/obo/GO_0032409 regulation of transporter activity 'regulation of transporter activity' SubClassOf 'regulation of transport' http://purl.obolibrary.org/obo/OBI_0001211 ex vivo design 'ex vivo design' SubClassOf 'study design' http://purl.obolibrary.org/obo/PR_000015224 solute carrier organic anion transporter family member 1B3 'solute carrier organic anion transporter family member 1B3' SubClassOf 'protein' http://purl.obolibrary.org/obo/PR_000015223 solute carrier organic anion transporter family member 1B1 'solute carrier organic anion transporter family member 1B1' SubClassOf 'protein' http://purl.obolibrary.org/obo/GO_0032410 negative regulation of transporter activity 'negative regulation of transporter activity' SubClassOf 'regulation of transporter activity' http://purl.obolibrary.org/obo/CL_0000010 cultured cell 'cultured cell' SubClassOf 'experimentally modified cell in vitro' http://purl.obolibrary.org/obo/GO_0051179 localization 'localization' SubClassOf 'biological_process' http://purl.obolibrary.org/obo/PR_000001891 multidrug resistance protein 1 'multidrug resistance protein 1' SubClassOf 'protein'