{"id":"http://purl.obolibrary.org/obo/CHEBI_168396","prefLabel":"mycophenolic acid","synonym":["acidum mycophenolicum","C17H20O6","(E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid","acide mycophenolique","acido micofenolico","mycophenolic acid","Micofenolico acido","Mycophenolsaeure","Mycophenolate","(4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid"],"prefixIRI":"obo2:CHEBI_168396","label":["mycophenolic acid"],"subClassOf":["http://purl.obolibrary.org/obo/dinto_000055"],"parents":[{"id":"http://purl.obolibrary.org/obo/dinto_000055","prefLabel":"pharmacological entity","prefixIRI":"obo2:dinto_000055","label":["pharmacological entity"],"definition":["This class imports chemical entities from the ChEBI ontology that have a relationship 'has role' with the class 'drug' in this ontology and other chemical entities included in the pharmacological database DrugBank (but not in ChEBI).\nTherefore all subclasses of the class 'pharmacological entity' share they capacity to produce some pharmacological activity within a biological system."],"subClassOf":["http://purl.obolibrary.org/obo/CHEBI_24431"],"prefLabelXl":[],"altLabelXl":[],"hiddenLabelXl":[],"synonym":[],"obsolete":false,"notation":null,"semanticType":[],"cui":[],"xref":null,"inScheme":[],"created":null,"modified":null,"@id":"http://purl.obolibrary.org/obo/dinto_000055","@type":"http://www.w3.org/2002/07/owl#Class","links":{"self":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055","ontology":"https://data.bioontology.org/ontologies/DINTO","children":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/children","parents":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/parents","descendants":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/descendants","ancestors":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/ancestors","instances":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/instances","tree":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/tree","notes":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/notes","mappings":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/mappings","ui":"http://bioportal.bioontology.org/ontologies/DINTO?p=classes&conceptid=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055","@context":{"self":"http://www.w3.org/2002/07/owl#Class","ontology":"http://data.bioontology.org/metadata/Ontology","children":"http://www.w3.org/2002/07/owl#Class","parents":"http://www.w3.org/2002/07/owl#Class","descendants":"http://www.w3.org/2002/07/owl#Class","ancestors":"http://www.w3.org/2002/07/owl#Class","instances":"http://data.bioontology.org/metadata/Instance","tree":"http://www.w3.org/2002/07/owl#Class","notes":"http://data.bioontology.org/metadata/Note","mappings":"http://data.bioontology.org/metadata/Mapping","ui":"http://www.w3.org/2002/07/owl#Class"}},"@context":{"@vocab":"http://data.bioontology.org/metadata/","label":"http://www.w3.org/2000/01/rdf-schema#label","prefLabel":"http://www.w3.org/2004/02/skos/core#prefLabel","prefLabelXl":"http://www.w3.org/2008/05/skos-xl#prefLabel","altLabelXl":"http://www.w3.org/2008/05/skos-xl#altLabel","hiddenLabelXl":"http://www.w3.org/2008/05/skos-xl#hiddenLabel","synonym":"http://www.w3.org/2004/02/skos/core#altLabel","definition":"http://www.w3.org/2004/02/skos/core#definition","obsolete":"http://www.w3.org/2002/07/owl#deprecated","notation":"http://www.w3.org/2004/02/skos/core#notation","prefixIRI":"http://data.bioontology.org/metadata/prefixIRI","subClassOf":"http://www.w3.org/2000/01/rdf-schema#subClassOf","semanticType":"http://bioportal.bioontology.org/ontologies/umls/hasSTY","cui":"http://bioportal.bioontology.org/ontologies/umls/cui","xref":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","inScheme":"http://www.w3.org/2004/02/skos/core#inScheme","created":"http://purl.org/dc/terms/created","modified":"http://purl.org/dc/terms/modified","@language":[]}}],"definition":[],"obsolete":false,"notation":null,"semanticType":[],"cui":[],"xref":null,"inScheme":[],"created":null,"modified":null,"memberOf":[],"altLabelXl":[],"hiddenLabelXl":[],"prefLabelXl":[],"isInActiveScheme":[null],"isInActiveCollection":[],"properties":{"http://purl.obolibrary.org/obo#DBSynonym":["mycophenoic acid"],"http://purl.obolibrary.org/obo#ATCCode":["L04AA06"],"https://data.bioontology.org/metadata/def/prefLabel":["mycophenolic acid"],"http://purl.obolibrary.org#Definition":["A member of the class of 2-benzofurans that is 2-benzofuran-1(3H)-one which is substituted at positions 4, 5, 6, and 7 by methyl, methoxy, (2E)-5-carboxy-3-methylpent-2-en-1-yl, and hydroxy groups, respectively. It is an antibiotic produced by Penicillium brevi-compactum, P. stoloniferum, P. echinulatum and related species. An immunosuppressant, it is widely used (partiularly as its sodium salt and as the 2-(morpholin-4-yl)ethyl ester prodrug, mycophenolate mofetil) to prevent tissue rejection following organ transplants and for the treatment of certain autoimmune diseases."],"http://purl.obolibrary.org/obo#altId":["CHEBI:43973"],"http://purl.obolibrary.org/obo/dinto_000303":["http://purl.obolibrary.org/obo/dinto_2809","http://purl.obolibrary.org/obo/dinto_3446"],"http://purl.obolibrary.org/obo/dinto_000404":["http://purl.obolibrary.org/obo/dinto_2809","http://purl.obolibrary.org/obo/dinto_3446"],"http://www.w3.org/1999/02/22-rdf-syntax-ns#type":["http://www.w3.org/2002/07/owl#Class"],"http://purl.obolibrary.org/obo/dinto_000154":["http://purl.obolibrary.org/obo/CHEBI_35705","http://purl.obolibrary.org/obo/CHEBI_35610","http://purl.obolibrary.org/obo/CHEBI_22582","http://purl.obolibrary.org/obo/CHEBI_26619","http://purl.obolibrary.org/obo/CHEBI_25442","http://purl.obolibrary.org/obo/CHEBI_53746"],"http://purl.obolibrary.org/obo#InChIKey":["InChIKey=HPNSFSBZBAHARI-RUDMXATFSA-N"],"http://purl.obolibrary.org/obo/dinto_000423":["http://purl.obolibrary.org/obo/dinto_1890","http://purl.obolibrary.org/obo/dinto_1701","http://purl.obolibrary.org/obo/dinto_0265","http://purl.obolibrary.org/obo/dinto_1712","http://purl.obolibrary.org/obo/dinto_0276"],"http://purl.obolibrary.org/obo#AHFScode":["92:00.00"],"http://purl.obolibrary.org/obo#Synonym":["acidum mycophenolicum","C17H20O6","(E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid","acide mycophenolique","acido micofenolico","mycophenolic acid","Micofenolico acido","Mycophenolsaeure","Mycophenolate","(4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid"],"http://purl.obolibrary.org/obo#xref":["National Drug Code Directory:0078-0386-66","DrugBank:DB01024","CiteXplore:15470161","PDBeChem:MOA","PharmGKB:PA164748728","KEGG DRUG:D05096","CiteXplore:16629948","CiteXplore:16640327","CASRN:24280-93-1","Reaxys:318158","Wikipedia:http://en.wikipedia.org/wiki/Mycophenolic_acid","BindingDB:19264","PubChem Compound:446541","PDB:MOA","ChemSpider:393865","Drugs.com:http://www.drugs.com/cdi/mycophenolic-acid-delayed-release-tablets.html","DrugBank:24280-93-1","Drugs Product Database (DPD):2264560","CiteXplore:18611107","Wikipedia:Mycophenolic_acid","CiteXplore:17498396","CiteXplore:11272311","Patent:US4753935","ChEBI:168396","CiteXplore:17482154","CiteXplore:18996104","CiteXplore:18194117","PubChem Substance:46504559","Beilstein:318158","CiteXplore:19689217"],"http://purl.obolibrary.org/obo#CASRN":["24280-93-1"],"https://data.bioontology.org/metadata/prefixIRI":["obo2:CHEBI_168396"],"http://purl.obolibrary.org/obo#SMILES":["COc1c(C)c2COC(=O)c2c(O)c1C\\\\C=C(/C)CCC(O)=O","COC1=C(C\\C=C(/C)CCC(O)=O)C(O)=C2C(=O)OCC2=C1C"],"http://purl.obolibrary.org/obo/dinto_000499":["http://purl.obolibrary.org/obo/CHEBI_63635","http://purl.obolibrary.org/obo/dinto_DB00072"],"http://www.w3.org/2000/01/rdf-schema#label":["mycophenolic acid"],"http://purl.obolibrary.org/obo#DBname":["mycophenolic acid"],"http://purl.obolibrary.org/obo#InChI":["InChI=1S/C17H20O6/c1-9(5-7-13(18)19)4-6-11-15(20)14-12(8-23-17(14)21)10(2)16(11)22-3/h4,20H,5-8H2,1-3H3,(H,18,19)/b9-4+"],"http://purl.obolibrary.org/obo#DBBrand":["melbex","myfortic"],"http://www.w3.org/2000/01/rdf-schema#subClassOf":["http://purl.obolibrary.org/obo/dinto_000055"]},"@id":"http://purl.obolibrary.org/obo/CHEBI_168396","@type":"http://www.w3.org/2002/07/owl#Class","links":{"self":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_168396","ontology":"https://data.bioontology.org/ontologies/DINTO","children":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_168396/children","parents":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_168396/parents","descendants":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_168396/descendants","ancestors":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_168396/ancestors","instances":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_168396/instances","tree":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_168396/tree","notes":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_168396/notes","mappings":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_168396/mappings","ui":"http://bioportal.bioontology.org/ontologies/DINTO?p=classes&conceptid=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_168396","@context":{"self":"http://www.w3.org/2002/07/owl#Class","ontology":"http://data.bioontology.org/metadata/Ontology","children":"http://www.w3.org/2002/07/owl#Class","parents":"http://www.w3.org/2002/07/owl#Class","descendants":"http://www.w3.org/2002/07/owl#Class","ancestors":"http://www.w3.org/2002/07/owl#Class","instances":"http://data.bioontology.org/metadata/Instance","tree":"http://www.w3.org/2002/07/owl#Class","notes":"http://data.bioontology.org/metadata/Note","mappings":"http://data.bioontology.org/metadata/Mapping","ui":"http://www.w3.org/2002/07/owl#Class"}},"@context":{"@vocab":"http://data.bioontology.org/metadata/","label":"http://www.w3.org/2000/01/rdf-schema#label","prefLabel":"http://www.w3.org/2004/02/skos/core#prefLabel","prefLabelXl":"http://www.w3.org/2008/05/skos-xl#prefLabel","altLabelXl":"http://www.w3.org/2008/05/skos-xl#altLabel","hiddenLabelXl":"http://www.w3.org/2008/05/skos-xl#hiddenLabel","synonym":"http://www.w3.org/2004/02/skos/core#altLabel","definition":"http://www.w3.org/2004/02/skos/core#definition","obsolete":"http://www.w3.org/2002/07/owl#deprecated","notation":"http://www.w3.org/2004/02/skos/core#notation","prefixIRI":"http://data.bioontology.org/metadata/prefixIRI","parents":"http://www.w3.org/2000/01/rdf-schema##","subClassOf":"http://www.w3.org/2000/01/rdf-schema#subClassOf","semanticType":"http://bioportal.bioontology.org/ontologies/umls/hasSTY","cui":"http://bioportal.bioontology.org/ontologies/umls/cui","xref":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","inScheme":"http://www.w3.org/2004/02/skos/core#inScheme","created":"http://purl.org/dc/terms/created","modified":"http://purl.org/dc/terms/modified","@language":[]}}