{"id":"http://purl.obolibrary.org/obo/CHEBI_31536","prefLabel":"emtricitabine","synonym":["(-)-FTC","4-amino-5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one","(-)-cis-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one","(2R-cis)-4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone","4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one","C8H10FN3O3S","(-)-2'-deoxy-5-fluoro-3'-thiacytidine","5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine","(-)-beta-2',3'-dideoxy-5-fluoro-3'-thiacytidine","(-)-(2R,5S)-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine","4-Amino-5-fluoro-1-((2R,5S)-2-hydroxymethyl-[1,3]oxathiolan-5-yl)-1H-pyrimidin-2-one","4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one","EMTRICITABINE","Emtricitabine"],"prefixIRI":"obo2:CHEBI_31536","label":["emtricitabine"],"subClassOf":["http://purl.obolibrary.org/obo/dinto_000055"],"parents":[{"id":"http://purl.obolibrary.org/obo/dinto_000055","prefLabel":"pharmacological entity","prefixIRI":"obo2:dinto_000055","label":["pharmacological entity"],"definition":["This class imports chemical entities from the ChEBI ontology that have a relationship 'has role' with the class 'drug' in this ontology and other chemical entities included in the pharmacological database DrugBank (but not in ChEBI).\nTherefore all subclasses of the class 'pharmacological entity' share they capacity to produce some pharmacological activity within a biological system."],"subClassOf":["http://purl.obolibrary.org/obo/CHEBI_24431"],"prefLabelXl":[],"altLabelXl":[],"hiddenLabelXl":[],"synonym":[],"obsolete":false,"notation":null,"semanticType":[],"cui":[],"xref":null,"inScheme":[],"created":null,"modified":null,"@id":"http://purl.obolibrary.org/obo/dinto_000055","@type":"http://www.w3.org/2002/07/owl#Class","links":{"self":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055","ontology":"https://data.bioontology.org/ontologies/DINTO","children":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/children","parents":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/parents","descendants":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/descendants","ancestors":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/ancestors","instances":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/instances","tree":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/tree","notes":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/notes","mappings":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/mappings","ui":"http://bioportal.bioontology.org/ontologies/DINTO?p=classes&conceptid=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055","@context":{"self":"http://www.w3.org/2002/07/owl#Class","ontology":"http://data.bioontology.org/metadata/Ontology","children":"http://www.w3.org/2002/07/owl#Class","parents":"http://www.w3.org/2002/07/owl#Class","descendants":"http://www.w3.org/2002/07/owl#Class","ancestors":"http://www.w3.org/2002/07/owl#Class","instances":"http://data.bioontology.org/metadata/Instance","tree":"http://www.w3.org/2002/07/owl#Class","notes":"http://data.bioontology.org/metadata/Note","mappings":"http://data.bioontology.org/metadata/Mapping","ui":"http://www.w3.org/2002/07/owl#Class"}},"@context":{"@vocab":"http://data.bioontology.org/metadata/","label":"http://www.w3.org/2000/01/rdf-schema#label","prefLabel":"http://www.w3.org/2004/02/skos/core#prefLabel","prefLabelXl":"http://www.w3.org/2008/05/skos-xl#prefLabel","altLabelXl":"http://www.w3.org/2008/05/skos-xl#altLabel","hiddenLabelXl":"http://www.w3.org/2008/05/skos-xl#hiddenLabel","synonym":"http://www.w3.org/2004/02/skos/core#altLabel","definition":"http://www.w3.org/2004/02/skos/core#definition","obsolete":"http://www.w3.org/2002/07/owl#deprecated","notation":"http://www.w3.org/2004/02/skos/core#notation","prefixIRI":"http://data.bioontology.org/metadata/prefixIRI","subClassOf":"http://www.w3.org/2000/01/rdf-schema#subClassOf","semanticType":"http://bioportal.bioontology.org/ontologies/umls/hasSTY","cui":"http://bioportal.bioontology.org/ontologies/umls/cui","xref":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","inScheme":"http://www.w3.org/2004/02/skos/core#inScheme","created":"http://purl.org/dc/terms/created","modified":"http://purl.org/dc/terms/modified","@language":[]}}],"definition":[],"obsolete":false,"notation":null,"semanticType":[],"cui":[],"xref":null,"inScheme":[],"created":null,"modified":null,"memberOf":[],"altLabelXl":[],"hiddenLabelXl":[],"prefLabelXl":[],"isInActiveScheme":[null],"isInActiveCollection":[],"properties":{"http://purl.obolibrary.org/obo#ATCCode":["J05AF09"],"https://data.bioontology.org/metadata/def/prefLabel":["emtricitabine"],"http://purl.obolibrary.org#Definition":["An organofluorine compound  that is 5-fluorocytosine substituted at the 1 position by a 2-(hydroxymethyl)-1,3-oxathiolan-5-yl group (2R,5S configuration). It is used in combination therapy for the treatment of HIV-1 infection."],"http://purl.obolibrary.org/obo#altId":["CHEBI:174911"],"http://purl.obolibrary.org/obo/dinto_000159":["http://purl.obolibrary.org/obo/OAE_0000388","http://purl.obolibrary.org/obo/OAE_0000496","http://purl.obolibrary.org/obo/OAE_0000453","http://purl.obolibrary.org/obo/OAE_0001373","http://purl.obolibrary.org/obo/OAE_0000557","http://purl.obolibrary.org/obo/OAE_0000377","http://purl.obolibrary.org/obo/OAE_0000391","http://purl.obolibrary.org/obo/OAE_0000376","http://purl.obolibrary.org/obo/OAE_0000567","http://purl.obolibrary.org/obo/OAE_0000195","http://purl.obolibrary.org/obo/OAE_0000373","http://purl.obolibrary.org/obo/OAE_0000418","http://purl.obolibrary.org/obo/OAE_0000210","http://purl.obolibrary.org/obo/OAE_0001448","http://purl.obolibrary.org/obo/OAE_0000382","http://purl.obolibrary.org/obo/OAE_0001033","http://purl.obolibrary.org/obo/OAE_0001397","http://purl.obolibrary.org/obo/OAE_0000600","http://purl.obolibrary.org/obo/OAE_0000340","http://purl.obolibrary.org/obo/OAE_0000601","http://purl.obolibrary.org/obo/OAE_0001357","http://purl.obolibrary.org/obo/OAE_0000375","http://purl.obolibrary.org/obo/OAE_0000386","http://purl.obolibrary.org/obo/OAE_0000455","http://purl.obolibrary.org/obo/OAE_0000584","http://purl.obolibrary.org/obo/OAE_0002206","http://purl.obolibrary.org/obo/OAE_0000034","http://purl.obolibrary.org/obo/OAE_0000647","http://purl.obolibrary.org/obo/OAE_0000385","http://purl.obolibrary.org/obo/OAE_0000336","http://purl.obolibrary.org/obo/OAE_0001217","http://purl.obolibrary.org/obo/OAE_0000362","http://purl.obolibrary.org/obo/OAE_0000374","http://purl.obolibrary.org/obo/OAE_0000358","http://purl.obolibrary.org/obo/OAE_0001035","http://purl.obolibrary.org/obo/OAE_0000402","http://purl.obolibrary.org/obo/OAE_0000350","http://purl.obolibrary.org/obo/OAE_0000345"],"http://purl.obolibrary.org/obo/dinto_000303":["http://purl.obolibrary.org/obo/dinto_1703"],"http://purl.obolibrary.org/obo/dinto_000404":["http://purl.obolibrary.org/obo/dinto_1703"],"http://www.w3.org/1999/02/22-rdf-syntax-ns#type":["http://www.w3.org/2002/07/owl#Class"],"http://purl.obolibrary.org/obo/dinto_000154":["http://purl.obolibrary.org/obo/CHEBI_53756","http://purl.obolibrary.org/obo/CHEBI_36044"],"http://purl.obolibrary.org/obo#InChIKey":["InChIKey=XQSPYNMVSIKCOC-NTSWFWBYSA-N"],"http://purl.obolibrary.org/obo/dinto_000423":["http://purl.obolibrary.org/obo/dinto_2044"],"http://purl.obolibrary.org/obo#AHFScode":["08:18.08.20"],"http://purl.obolibrary.org/obo#Synonym":["(-)-FTC","4-amino-5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one","(-)-cis-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one","(2R-cis)-4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone","4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one","C8H10FN3O3S","(-)-2'-deoxy-5-fluoro-3'-thiacytidine","5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine","(-)-beta-2',3'-dideoxy-5-fluoro-3'-thiacytidine","(-)-(2R,5S)-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine","4-Amino-5-fluoro-1-((2R,5S)-2-hydroxymethyl-[1,3]oxathiolan-5-yl)-1H-pyrimidin-2-one","4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one","EMTRICITABINE","Emtricitabine"],"http://purl.obolibrary.org/obo#xref":["Beilstein:5908714","CiteXplore:16034488","KEGG COMPOUND:C12599","PubChem Compound:60877","Wikipedia:http://en.wikipedia.org/wiki/Emtricitabine","CiteXplore:23361642","CiteXplore:19493710","DrugBank:DB00879","RxList:http://www.rxlist.com/cgi/generic3/emtriva.htm","CiteXplore:22915463","Drugs.com:http://www.drugs.com/cdi/emtricitabine.html","CiteXplore:16401810","CiteXplore:11491420","National Drug Code Directory:61958-0602-1","Patent:US5538975","CiteXplore:16323102","Wikipedia:Emtricitabine","CiteXplore:15588339","CiteXplore:17526857","CiteXplore:14693538","CiteXplore:22917277","Patent:WO9214743","KEGG DRUG:D01199","PharmGKB:PA10069","CiteXplore:14609348","ChEBI:31536","CiteXplore:22935078","CASRN:143491-57-0","ChemSpider:54859","CiteXplore:23337366","CiteXplore:15249567","CiteXplore:15875341","BindingDB:50046283","PubChem Substance:46507606","CiteXplore:15977972","CiteXplore:15206508"],"http://purl.obolibrary.org/obo#CASRN":["143491-57-0"],"https://data.bioontology.org/metadata/prefixIRI":["obo2:CHEBI_31536"],"http://purl.obolibrary.org/obo#SMILES":["NC1=NC(=O)N(C=C1F)[C@@H]1CS[C@H](CO)O1","Nc1nc(=O)n(cc1F)[C@@H]1CS[C@H](CO)O1"],"http://purl.obolibrary.org/obo/dinto_000499":["http://purl.obolibrary.org/obo/CHEBI_63635"],"http://www.w3.org/2000/01/rdf-schema#label":["emtricitabine"],"http://purl.obolibrary.org/obo#DBname":["emtricitabine"],"http://purl.obolibrary.org/obo#InChI":["InChI=1S/C8H10FN3O3S/c9-4-1-12(8(14)11-7(4)10)5-3-16-6(2-13)15-5/h1,5-6,13H,2-3H2,(H2,10,11,14)/t5-,6+/m0/s1"],"http://purl.obolibrary.org/obo#DBBrand":["emtriva","coviracil","racivir"],"http://www.w3.org/2000/01/rdf-schema#subClassOf":["http://purl.obolibrary.org/obo/dinto_000055"]},"@id":"http://purl.obolibrary.org/obo/CHEBI_31536","@type":"http://www.w3.org/2002/07/owl#Class","links":{"self":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_31536","ontology":"https://data.bioontology.org/ontologies/DINTO","children":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_31536/children","parents":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_31536/parents","descendants":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_31536/descendants","ancestors":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_31536/ancestors","instances":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_31536/instances","tree":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_31536/tree","notes":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_31536/notes","mappings":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_31536/mappings","ui":"http://bioportal.bioontology.org/ontologies/DINTO?p=classes&conceptid=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_31536","@context":{"self":"http://www.w3.org/2002/07/owl#Class","ontology":"http://data.bioontology.org/metadata/Ontology","children":"http://www.w3.org/2002/07/owl#Class","parents":"http://www.w3.org/2002/07/owl#Class","descendants":"http://www.w3.org/2002/07/owl#Class","ancestors":"http://www.w3.org/2002/07/owl#Class","instances":"http://data.bioontology.org/metadata/Instance","tree":"http://www.w3.org/2002/07/owl#Class","notes":"http://data.bioontology.org/metadata/Note","mappings":"http://data.bioontology.org/metadata/Mapping","ui":"http://www.w3.org/2002/07/owl#Class"}},"@context":{"@vocab":"http://data.bioontology.org/metadata/","label":"http://www.w3.org/2000/01/rdf-schema#label","prefLabel":"http://www.w3.org/2004/02/skos/core#prefLabel","prefLabelXl":"http://www.w3.org/2008/05/skos-xl#prefLabel","altLabelXl":"http://www.w3.org/2008/05/skos-xl#altLabel","hiddenLabelXl":"http://www.w3.org/2008/05/skos-xl#hiddenLabel","synonym":"http://www.w3.org/2004/02/skos/core#altLabel","definition":"http://www.w3.org/2004/02/skos/core#definition","obsolete":"http://www.w3.org/2002/07/owl#deprecated","notation":"http://www.w3.org/2004/02/skos/core#notation","prefixIRI":"http://data.bioontology.org/metadata/prefixIRI","parents":"http://www.w3.org/2000/01/rdf-schema##<Proc:0x00007f453dc33af0 /opt/ontoportal/ontologies_api/shared/bundle/ruby/3.2.0/bundler/gems/ontologies_linked_data-0083660248b7/lib/ontologies_linked_data/models/class.rb:67 (lambda)>","subClassOf":"http://www.w3.org/2000/01/rdf-schema#subClassOf","semanticType":"http://bioportal.bioontology.org/ontologies/umls/hasSTY","cui":"http://bioportal.bioontology.org/ontologies/umls/cui","xref":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","inScheme":"http://www.w3.org/2004/02/skos/core#inScheme","created":"http://purl.org/dc/terms/created","modified":"http://purl.org/dc/terms/modified","@language":[]}}