{"id":"http://purl.obolibrary.org/obo/CHEBI_3640","prefLabel":"chlorothiazide","synonym":["chlorothiazide","Chlorothiazide","6-chloro-1,1-dioxo-4H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide","chlorothiazidum","6-Chloro-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[1,2,4]thiadiazine-7-sulfonic acid amide","C7H6ClN3O4S2","6-chloro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide","clorotiazida","6-chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide"],"prefixIRI":"obo2:CHEBI_3640","label":["chlorothiazide"],"subClassOf":["http://purl.obolibrary.org/obo/dinto_000055"],"parents":[{"id":"http://purl.obolibrary.org/obo/dinto_000055","prefLabel":"pharmacological entity","prefixIRI":"obo2:dinto_000055","label":["pharmacological entity"],"definition":["This class imports chemical entities from the ChEBI ontology that have a relationship 'has role' with the class 'drug' in this ontology and other chemical entities included in the pharmacological database DrugBank (but not in ChEBI).\nTherefore all subclasses of the class 'pharmacological entity' share they capacity to produce some pharmacological activity within a biological system."],"subClassOf":["http://purl.obolibrary.org/obo/CHEBI_24431"],"prefLabelXl":[],"altLabelXl":[],"hiddenLabelXl":[],"synonym":[],"obsolete":false,"notation":null,"semanticType":[],"cui":[],"xref":null,"inScheme":[],"created":null,"modified":null,"@id":"http://purl.obolibrary.org/obo/dinto_000055","@type":"http://www.w3.org/2002/07/owl#Class","links":{"self":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055","ontology":"https://data.bioontology.org/ontologies/DINTO","children":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/children","parents":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/parents","descendants":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/descendants","ancestors":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/ancestors","instances":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/instances","tree":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/tree","notes":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/notes","mappings":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/mappings","ui":"http://bioportal.bioontology.org/ontologies/DINTO?p=classes&conceptid=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055","@context":{"self":"http://www.w3.org/2002/07/owl#Class","ontology":"http://data.bioontology.org/metadata/Ontology","children":"http://www.w3.org/2002/07/owl#Class","parents":"http://www.w3.org/2002/07/owl#Class","descendants":"http://www.w3.org/2002/07/owl#Class","ancestors":"http://www.w3.org/2002/07/owl#Class","instances":"http://data.bioontology.org/metadata/Instance","tree":"http://www.w3.org/2002/07/owl#Class","notes":"http://data.bioontology.org/metadata/Note","mappings":"http://data.bioontology.org/metadata/Mapping","ui":"http://www.w3.org/2002/07/owl#Class"}},"@context":{"@vocab":"http://data.bioontology.org/metadata/","label":"http://www.w3.org/2000/01/rdf-schema#label","prefLabel":"http://www.w3.org/2004/02/skos/core#prefLabel","prefLabelXl":"http://www.w3.org/2008/05/skos-xl#prefLabel","altLabelXl":"http://www.w3.org/2008/05/skos-xl#altLabel","hiddenLabelXl":"http://www.w3.org/2008/05/skos-xl#hiddenLabel","synonym":"http://www.w3.org/2004/02/skos/core#altLabel","definition":"http://www.w3.org/2004/02/skos/core#definition","obsolete":"http://www.w3.org/2002/07/owl#deprecated","notation":"http://www.w3.org/2004/02/skos/core#notation","prefixIRI":"http://data.bioontology.org/metadata/prefixIRI","subClassOf":"http://www.w3.org/2000/01/rdf-schema#subClassOf","semanticType":"http://bioportal.bioontology.org/ontologies/umls/hasSTY","cui":"http://bioportal.bioontology.org/ontologies/umls/cui","xref":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","inScheme":"http://www.w3.org/2004/02/skos/core#inScheme","created":"http://purl.org/dc/terms/created","modified":"http://purl.org/dc/terms/modified","@language":[]}}],"definition":[],"obsolete":false,"notation":null,"semanticType":[],"cui":[],"xref":null,"inScheme":[],"created":null,"modified":null,"memberOf":[],"altLabelXl":[],"hiddenLabelXl":[],"prefLabelXl":[],"isInActiveScheme":[null],"isInActiveCollection":[],"properties":{"http://purl.obolibrary.org/obo#DBSynonym":["chlorthiazide","chlorothiazid","chlortiazid"],"http://purl.obolibrary.org/obo#ATCCode":["C03AA04","C03AA03"],"https://data.bioontology.org/metadata/def/prefLabel":["chlorothiazide"],"http://purl.obolibrary.org#Definition":["4H-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position is substituted by chlorine and that at position 7 is substituted by a sulfonamide group. A diuretic, it is used for treatment of oedema and hypertension."],"http://purl.obolibrary.org/obo#altId":["CHEBI:162615"],"http://purl.obolibrary.org/obo/dinto_000303":["http://purl.obolibrary.org/obo/dinto_0512","http://purl.obolibrary.org/obo/dinto_0757","http://purl.obolibrary.org/obo/dinto_1621","http://purl.obolibrary.org/obo/dinto_2115"],"http://purl.obolibrary.org/obo/dinto_000404":["http://purl.obolibrary.org/obo/dinto_0512","http://purl.obolibrary.org/obo/dinto_0757","http://purl.obolibrary.org/obo/dinto_1621","http://purl.obolibrary.org/obo/dinto_0520","http://purl.obolibrary.org/obo/dinto_2115"],"http://www.w3.org/1999/02/22-rdf-syntax-ns#type":["http://www.w3.org/2002/07/owl#Class"],"http://purl.obolibrary.org/obo/dinto_000154":["http://purl.obolibrary.org/obo/CHEBI_35498","http://purl.obolibrary.org/obo/CHEBI_35674"],"http://purl.obolibrary.org/obo#InChIKey":["InChIKey=JBMKAUGHUNFTOL-UHFFFAOYSA-N"],"http://purl.obolibrary.org/obo#Synonym":["chlorothiazide","Chlorothiazide","6-chloro-1,1-dioxo-4H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide","chlorothiazidum","6-Chloro-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[1,2,4]thiadiazine-7-sulfonic acid amide","C7H6ClN3O4S2","6-chloro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide","clorotiazida","6-chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide"],"http://purl.obolibrary.org/obo#xref":["ChEMBL:3712385","Drugs Product Database (DPD):231169","ChEMBL:10891117","Patent:US2809194","PharmGKB:PA448953","National Drug Code Directory:0378-0150-01","DrugBank:DB00880","RxList:http://www.rxlist.com/cgi/generic2/chloroth.htm","Wikipedia:Chlorothiazide","CASRN:58-94-6","KEGG DRUG:D00519","ChemSpider:2619","ChEBI:3640","Beilstein:1084805","ChEMBL:2160536","PubChem Compound:2720","PubChem Substance:46507032","KEGG COMPOUND:C07461","Drugs.com:http://www.drugs.com/cdi/chlorothiazide.html","NIST Chemistry WebBook:58-94-6","Wikipedia:http://en.wikipedia.org/wiki/Chlorothiazide"],"http://purl.obolibrary.org/obo#CASRN":["58-94-6"],"https://data.bioontology.org/metadata/prefixIRI":["obo2:CHEBI_3640"],"http://purl.obolibrary.org/obo#SMILES":["NS(=O)(=O)c1cc2c(NC=NS2(=O)=O)cc1Cl","NS(=O)(=O)C1=C(Cl)C=C2NC=NS(=O)(=O)C2=C1"],"http://purl.obolibrary.org/obo/dinto_000499":["http://purl.obolibrary.org/obo/dinto_DB00519","http://purl.obolibrary.org/obo/CHEBI_4551","http://purl.obolibrary.org/obo/CHEBI_63631","http://purl.obolibrary.org/obo/dinto_DB01356","http://purl.obolibrary.org/obo/CHEBI_50861","http://purl.obolibrary.org/obo/dinto_DB00073","http://purl.obolibrary.org/obo/CHEBI_2636","http://purl.obolibrary.org/obo/CHEBI_59602","http://purl.obolibrary.org/obo/dinto_DB01432","http://purl.obolibrary.org/obo/CHEBI_4681"],"http://www.w3.org/2000/01/rdf-schema#label":["chlorothiazide"],"http://purl.obolibrary.org/obo#DBname":["chlorothiazide"],"http://purl.obolibrary.org/obo#InChI":["InChI=1S/C7H6ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-3H,(H,10,11)(H2,9,12,13)"],"http://purl.obolibrary.org/obo#DBBrand":["saluric","diuril","chlotride","clotride","azide"],"http://www.w3.org/2000/01/rdf-schema#subClassOf":["http://purl.obolibrary.org/obo/dinto_000055"]},"@id":"http://purl.obolibrary.org/obo/CHEBI_3640","@type":"http://www.w3.org/2002/07/owl#Class","links":{"self":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_3640","ontology":"https://data.bioontology.org/ontologies/DINTO","children":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_3640/children","parents":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_3640/parents","descendants":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_3640/descendants","ancestors":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_3640/ancestors","instances":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_3640/instances","tree":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_3640/tree","notes":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_3640/notes","mappings":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_3640/mappings","ui":"http://bioportal.bioontology.org/ontologies/DINTO?p=classes&conceptid=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FCHEBI_3640","@context":{"self":"http://www.w3.org/2002/07/owl#Class","ontology":"http://data.bioontology.org/metadata/Ontology","children":"http://www.w3.org/2002/07/owl#Class","parents":"http://www.w3.org/2002/07/owl#Class","descendants":"http://www.w3.org/2002/07/owl#Class","ancestors":"http://www.w3.org/2002/07/owl#Class","instances":"http://data.bioontology.org/metadata/Instance","tree":"http://www.w3.org/2002/07/owl#Class","notes":"http://data.bioontology.org/metadata/Note","mappings":"http://data.bioontology.org/metadata/Mapping","ui":"http://www.w3.org/2002/07/owl#Class"}},"@context":{"@vocab":"http://data.bioontology.org/metadata/","label":"http://www.w3.org/2000/01/rdf-schema#label","prefLabel":"http://www.w3.org/2004/02/skos/core#prefLabel","prefLabelXl":"http://www.w3.org/2008/05/skos-xl#prefLabel","altLabelXl":"http://www.w3.org/2008/05/skos-xl#altLabel","hiddenLabelXl":"http://www.w3.org/2008/05/skos-xl#hiddenLabel","synonym":"http://www.w3.org/2004/02/skos/core#altLabel","definition":"http://www.w3.org/2004/02/skos/core#definition","obsolete":"http://www.w3.org/2002/07/owl#deprecated","notation":"http://www.w3.org/2004/02/skos/core#notation","prefixIRI":"http://data.bioontology.org/metadata/prefixIRI","parents":"http://www.w3.org/2000/01/rdf-schema##","subClassOf":"http://www.w3.org/2000/01/rdf-schema#subClassOf","semanticType":"http://bioportal.bioontology.org/ontologies/umls/hasSTY","cui":"http://bioportal.bioontology.org/ontologies/umls/cui","xref":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","inScheme":"http://www.w3.org/2004/02/skos/core#inScheme","created":"http://purl.org/dc/terms/created","modified":"http://purl.org/dc/terms/modified","@language":[]}}