{"id":"http://purl.obolibrary.org/obo/dinto_DB00822","prefLabel":"disulfiram","synonym":["N,N-diethyl[(diethylcarbamothioyl)disulfanyl]carbothioamide","C10H20N2S4"],"prefixIRI":"obo2:dinto_DB00822","label":["disulfiram"],"subClassOf":["http://purl.obolibrary.org/obo/dinto_000055"],"parents":[{"id":"http://purl.obolibrary.org/obo/dinto_000055","prefLabel":"pharmacological entity","prefixIRI":"obo2:dinto_000055","label":["pharmacological entity"],"definition":["This class imports chemical entities from the ChEBI ontology that have a relationship 'has role' with the class 'drug' in this ontology and other chemical entities included in the pharmacological database DrugBank (but not in ChEBI).\nTherefore all subclasses of the class 'pharmacological entity' share they capacity to produce some pharmacological activity within a biological system."],"subClassOf":["http://purl.obolibrary.org/obo/CHEBI_24431"],"prefLabelXl":[],"altLabelXl":[],"hiddenLabelXl":[],"synonym":[],"obsolete":false,"notation":null,"semanticType":[],"cui":[],"xref":null,"inScheme":[],"created":null,"modified":null,"@id":"http://purl.obolibrary.org/obo/dinto_000055","@type":"http://www.w3.org/2002/07/owl#Class","links":{"self":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055","ontology":"https://data.bioontology.org/ontologies/DINTO","children":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/children","parents":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/parents","descendants":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/descendants","ancestors":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/ancestors","instances":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/instances","tree":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/tree","notes":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/notes","mappings":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/mappings","ui":"http://bioportal.bioontology.org/ontologies/DINTO?p=classes&conceptid=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055","@context":{"self":"http://www.w3.org/2002/07/owl#Class","ontology":"http://data.bioontology.org/metadata/Ontology","children":"http://www.w3.org/2002/07/owl#Class","parents":"http://www.w3.org/2002/07/owl#Class","descendants":"http://www.w3.org/2002/07/owl#Class","ancestors":"http://www.w3.org/2002/07/owl#Class","instances":"http://data.bioontology.org/metadata/Instance","tree":"http://www.w3.org/2002/07/owl#Class","notes":"http://data.bioontology.org/metadata/Note","mappings":"http://data.bioontology.org/metadata/Mapping","ui":"http://www.w3.org/2002/07/owl#Class"}},"@context":{"@vocab":"http://data.bioontology.org/metadata/","label":"http://www.w3.org/2000/01/rdf-schema#label","prefLabel":"http://www.w3.org/2004/02/skos/core#prefLabel","prefLabelXl":"http://www.w3.org/2008/05/skos-xl#prefLabel","altLabelXl":"http://www.w3.org/2008/05/skos-xl#altLabel","hiddenLabelXl":"http://www.w3.org/2008/05/skos-xl#hiddenLabel","synonym":"http://www.w3.org/2004/02/skos/core#altLabel","definition":"http://www.w3.org/2004/02/skos/core#definition","obsolete":"http://www.w3.org/2002/07/owl#deprecated","notation":"http://www.w3.org/2004/02/skos/core#notation","prefixIRI":"http://data.bioontology.org/metadata/prefixIRI","subClassOf":"http://www.w3.org/2000/01/rdf-schema#subClassOf","semanticType":"http://bioportal.bioontology.org/ontologies/umls/hasSTY","cui":"http://bioportal.bioontology.org/ontologies/umls/cui","xref":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","inScheme":"http://www.w3.org/2004/02/skos/core#inScheme","created":"http://purl.org/dc/terms/created","modified":"http://purl.org/dc/terms/modified","@language":[]}}],"definition":[],"obsolete":false,"notation":null,"semanticType":[],"cui":[],"xref":null,"inScheme":[],"created":null,"modified":null,"memberOf":[],"altLabelXl":[],"hiddenLabelXl":[],"prefLabelXl":[],"isInActiveScheme":[null],"isInActiveCollection":[],"properties":{"http://purl.obolibrary.org/obo#DBSynonym":["ttd","tatd","tetraethylthiram disulphide","tetraethylthiuram disulphide","disulphuram","tetraethylthiuram sulfide","tetd","dupon 4472","tetraethylthiuran disulfide","tetraethylthiuram disulfide","usaf b-33","tetraethylthiram disulfide","disulfuram","dupont fungicide 4472","tetraethylthiuram","tetraethylthioperoxydicarbonic diamide"],"http://purl.obolibrary.org/obo#ATCCode":["N07BB01","P03AA04"],"https://data.bioontology.org/metadata/def/prefLabel":["disulfiram"],"http://purl.obolibrary.org#Definition":["A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase. [PubChem]"],"http://purl.obolibrary.org/obo/dinto_000159":["http://purl.obolibrary.org/obo/OAE_0000377","http://purl.obolibrary.org/obo/OAE_0000921","http://purl.obolibrary.org/obo/OAE_0000418","http://purl.obolibrary.org/obo/OAE_0000210","http://purl.obolibrary.org/obo/OAE_0001026","http://purl.obolibrary.org/obo/OAE_0000632","http://purl.obolibrary.org/obo/OAE_0000086","http://purl.obolibrary.org/obo/OAE_0001336","http://purl.obolibrary.org/obo/OAE_0000506"],"http://purl.obolibrary.org/obo/dinto_000303":["http://purl.obolibrary.org/obo/dinto_2840","http://purl.obolibrary.org/obo/dinto_2685"],"http://purl.obolibrary.org/obo/dinto_000404":["http://purl.obolibrary.org/obo/dinto_2058","http://purl.obolibrary.org/obo/dinto_2840","http://purl.obolibrary.org/obo/dinto_0293","http://purl.obolibrary.org/obo/dinto_2685"],"http://www.w3.org/1999/02/22-rdf-syntax-ns#type":["http://www.w3.org/2002/07/owl#Class"],"http://purl.obolibrary.org/obo#InChIKey":["InChIKey=AUZONCFQVSMFAP-UHFFFAOYSA-N"],"http://purl.obolibrary.org/obo/dinto_000423":["http://purl.obolibrary.org/obo/dinto_2990","http://purl.obolibrary.org/obo/dinto_0901"],"http://purl.obolibrary.org/obo#Synonym":["N,N-diethyl[(diethylcarbamothioyl)disulfanyl]carbothioamide","C10H20N2S4"],"http://purl.obolibrary.org/obo#xref":["ChemSpider:3005","National Drug Code Directory:49884-153-01","ChEBI:4659","Wikipedia:http://en.wikipedia.org/wiki/Disulfiram","RxList:http://www.rxlist.com/cgi/generic/disulfiram.htm","PubChem Substance:46506008","Drugs.com:http://www.drugs.com/cdi/disulfiram.html","PharmGKB:PA449376","Drugs Product Database (DPD):2534","PubChem Compound:3117"],"http://purl.obolibrary.org/obo#CASRN":["97-77-8"],"https://data.bioontology.org/metadata/prefixIRI":["obo2:dinto_DB00822"],"http://purl.obolibrary.org/obo#SMILES":["CCN(CC)C(=S)SSC(=S)N(CC)CC"],"http://purl.obolibrary.org/obo/dinto_000499":["http://purl.obolibrary.org/obo/dinto_DB01303","http://purl.obolibrary.org/obo/CHEBI_8107","http://purl.obolibrary.org/obo/CHEBI_3655","http://purl.obolibrary.org/obo/CHEBI_4888","http://purl.obolibrary.org/obo/CHEBI_40050","http://purl.obolibrary.org/obo/dinto_DB01223","http://purl.obolibrary.org/obo/dinto_DB00532","http://purl.obolibrary.org/obo/CHEBI_53766","http://purl.obolibrary.org/obo/CHEBI_133809","http://purl.obolibrary.org/obo/CHEBI_4728","http://purl.obolibrary.org/obo/CHEBI_6909","http://purl.obolibrary.org/obo/CHEBI_10033","http://purl.obolibrary.org/obo/CHEBI_63628","http://purl.obolibrary.org/obo/CHEBI_4513","http://purl.obolibrary.org/obo/CHEBI_27958","http://purl.obolibrary.org/obo/dinto_DB00347","http://purl.obolibrary.org/obo/dinto_DB01320","http://purl.obolibrary.org/obo/CHEBI_28177","http://purl.obolibrary.org/obo/dinto_DB00951"],"http://www.w3.org/2000/01/rdf-schema#label":["disulfiram"],"http://purl.obolibrary.org/obo#InChI":["InChI=1S/C10H20N2S4/c1-5-11(6-2)9(13)15-16-10(14)12(7-3)8-4/h5-8H2,1-4H3"],"http://purl.obolibrary.org/obo#DBBrand":["ekagom tetds","refusal","cronetal","ethyl thiram","ro-sulfiram","tts x","anti-ethyl","ekagom dtet","super rodiatox","ethyl thiurad","thireranide","antikol","stopethyl","antetil","abstinil","anticol","soxinol tet","accel tet-r","etabus","antaetil","perkait tetd","tetraetil","abstensil","ethyl tuex","ancazide et","antetan","alk-aubs","tetidis","alcophobin","nocceler tet","antivitium","teturam","abstinyl","tts","accel tet","antadix","perkacit tetd","bonibal","nocceler tet-g","antaethan","thiocid","akrochem tetd","disulfram","ethyldithiourame","anthethyl","tetradin","stopetyl","thiophos","antietil","antaenyl","ethyl tuads rodform","sanceler tet","tetradine","antietanol","ethyldithiurame","contralin","esperal","dicupral","antabus","aversan","espenal","nocbin","averzan","sanceler tet-g","ekagom teds","ethyl tuads","tenutex","teturamin","stopaethyl","anteyl","antaethyl","noxal","antalcol","exhoran","tenurid","krotenal","hoca","antiaethan","contrapot","disetil","tillram","ekaland tetd","antabuse","exhorran","ephorran","stopety","tiuram","disulfan","ethyl thiudad","gababentin","etyl tuex","antethyl"],"http://www.w3.org/2000/01/rdf-schema#subClassOf":["http://purl.obolibrary.org/obo/dinto_000055"]},"@id":"http://purl.obolibrary.org/obo/dinto_DB00822","@type":"http://www.w3.org/2002/07/owl#Class","links":{"self":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_DB00822","ontology":"https://data.bioontology.org/ontologies/DINTO","children":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_DB00822/children","parents":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_DB00822/parents","descendants":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_DB00822/descendants","ancestors":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_DB00822/ancestors","instances":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_DB00822/instances","tree":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_DB00822/tree","notes":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_DB00822/notes","mappings":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_DB00822/mappings","ui":"http://bioportal.bioontology.org/ontologies/DINTO?p=classes&conceptid=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_DB00822","@context":{"self":"http://www.w3.org/2002/07/owl#Class","ontology":"http://data.bioontology.org/metadata/Ontology","children":"http://www.w3.org/2002/07/owl#Class","parents":"http://www.w3.org/2002/07/owl#Class","descendants":"http://www.w3.org/2002/07/owl#Class","ancestors":"http://www.w3.org/2002/07/owl#Class","instances":"http://data.bioontology.org/metadata/Instance","tree":"http://www.w3.org/2002/07/owl#Class","notes":"http://data.bioontology.org/metadata/Note","mappings":"http://data.bioontology.org/metadata/Mapping","ui":"http://www.w3.org/2002/07/owl#Class"}},"@context":{"@vocab":"http://data.bioontology.org/metadata/","label":"http://www.w3.org/2000/01/rdf-schema#label","prefLabel":"http://www.w3.org/2004/02/skos/core#prefLabel","prefLabelXl":"http://www.w3.org/2008/05/skos-xl#prefLabel","altLabelXl":"http://www.w3.org/2008/05/skos-xl#altLabel","hiddenLabelXl":"http://www.w3.org/2008/05/skos-xl#hiddenLabel","synonym":"http://www.w3.org/2004/02/skos/core#altLabel","definition":"http://www.w3.org/2004/02/skos/core#definition","obsolete":"http://www.w3.org/2002/07/owl#deprecated","notation":"http://www.w3.org/2004/02/skos/core#notation","prefixIRI":"http://data.bioontology.org/metadata/prefixIRI","parents":"http://www.w3.org/2000/01/rdf-schema##<Proc:0x00007fbd5ffec6e8 /opt/ontoportal/ontologies_api/shared/bundle/ruby/3.2.0/bundler/gems/ontologies_linked_data-0083660248b7/lib/ontologies_linked_data/models/class.rb:67 (lambda)>","subClassOf":"http://www.w3.org/2000/01/rdf-schema#subClassOf","semanticType":"http://bioportal.bioontology.org/ontologies/umls/hasSTY","cui":"http://bioportal.bioontology.org/ontologies/umls/cui","xref":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","inScheme":"http://www.w3.org/2004/02/skos/core#inScheme","created":"http://purl.org/dc/terms/created","modified":"http://purl.org/dc/terms/modified","@language":[]}}