{"id":"http://purl.obolibrary.org/obo/dinto_DB06781","prefLabel":"difluprednate","synonym":["C27H34F2O7","(1R,2S,8S,10S,11S,14R,15S,17S)-14-[2-(acetyloxy)acetyl]-1,8-difluoro-17-hydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-14-yl butanoate"],"prefixIRI":"obo2:dinto_DB06781","label":["difluprednate"],"subClassOf":["http://purl.obolibrary.org/obo/dinto_000055"],"parents":[{"id":"http://purl.obolibrary.org/obo/dinto_000055","prefLabel":"pharmacological entity","prefixIRI":"obo2:dinto_000055","label":["pharmacological entity"],"definition":["This class imports chemical entities from the ChEBI ontology that have a relationship 'has role' with the class 'drug' in this ontology and other chemical entities included in the pharmacological database DrugBank (but not in ChEBI).\nTherefore all subclasses of the class 'pharmacological entity' share they capacity to produce some pharmacological activity within a biological system."],"subClassOf":["http://purl.obolibrary.org/obo/CHEBI_24431"],"prefLabelXl":[],"altLabelXl":[],"hiddenLabelXl":[],"synonym":[],"obsolete":false,"notation":null,"semanticType":[],"cui":[],"xref":null,"inScheme":[],"created":null,"modified":null,"@id":"http://purl.obolibrary.org/obo/dinto_000055","@type":"http://www.w3.org/2002/07/owl#Class","links":{"self":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055","ontology":"https://data.bioontology.org/ontologies/DINTO","children":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/children","parents":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/parents","descendants":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/descendants","ancestors":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/ancestors","instances":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/instances","tree":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/tree","notes":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/notes","mappings":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055/mappings","ui":"http://bioportal.bioontology.org/ontologies/DINTO?p=classes&conceptid=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_000055","@context":{"self":"http://www.w3.org/2002/07/owl#Class","ontology":"http://data.bioontology.org/metadata/Ontology","children":"http://www.w3.org/2002/07/owl#Class","parents":"http://www.w3.org/2002/07/owl#Class","descendants":"http://www.w3.org/2002/07/owl#Class","ancestors":"http://www.w3.org/2002/07/owl#Class","instances":"http://data.bioontology.org/metadata/Instance","tree":"http://www.w3.org/2002/07/owl#Class","notes":"http://data.bioontology.org/metadata/Note","mappings":"http://data.bioontology.org/metadata/Mapping","ui":"http://www.w3.org/2002/07/owl#Class"}},"@context":{"@vocab":"http://data.bioontology.org/metadata/","label":"http://www.w3.org/2000/01/rdf-schema#label","prefLabel":"http://www.w3.org/2004/02/skos/core#prefLabel","prefLabelXl":"http://www.w3.org/2008/05/skos-xl#prefLabel","altLabelXl":"http://www.w3.org/2008/05/skos-xl#altLabel","hiddenLabelXl":"http://www.w3.org/2008/05/skos-xl#hiddenLabel","synonym":"http://www.w3.org/2004/02/skos/core#altLabel","definition":"http://www.w3.org/2004/02/skos/core#definition","obsolete":"http://www.w3.org/2002/07/owl#deprecated","notation":"http://www.w3.org/2004/02/skos/core#notation","prefixIRI":"http://data.bioontology.org/metadata/prefixIRI","subClassOf":"http://www.w3.org/2000/01/rdf-schema#subClassOf","semanticType":"http://bioportal.bioontology.org/ontologies/umls/hasSTY","cui":"http://bioportal.bioontology.org/ontologies/umls/cui","xref":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","inScheme":"http://www.w3.org/2004/02/skos/core#inScheme","created":"http://purl.org/dc/terms/created","modified":"http://purl.org/dc/terms/modified","@language":[]}}],"definition":[],"obsolete":false,"notation":null,"semanticType":[],"cui":[],"xref":null,"inScheme":[],"created":null,"modified":null,"memberOf":[],"altLabelXl":[],"hiddenLabelXl":[],"prefLabelXl":[],"isInActiveScheme":[null],"isInActiveCollection":[],"properties":{"http://purl.obolibrary.org/obo#DBSynonym":["durezol","dfba","difluoroprednisolone butyrate acetate"],"http://purl.obolibrary.org/obo#ATCCode":["D07AC19"],"https://data.bioontology.org/metadata/def/prefLabel":["difluprednate"],"http://purl.obolibrary.org#Definition":["Difluprednate is a topical corticosteroid indicated for the treatment of infammation and pain associated with ocular surgery. It is a butyrate ester of 6(?), 9(?)-difluoro prednisolone acetate. Difluprednate is abbreviated DFBA, or difluoroprednisolone butyrate acetate. It is indicated for treatment of endogenous anterior uveiti."],"http://purl.obolibrary.org/obo/dinto_000303":["http://purl.obolibrary.org/obo/dinto_2874"],"http://purl.obolibrary.org/obo/dinto_000430":["http://purl.obolibrary.org/obo/dinto_2874"],"http://www.w3.org/1999/02/22-rdf-syntax-ns#type":["http://www.w3.org/2002/07/owl#Class"],"http://purl.obolibrary.org/obo#InChIKey":["InChIKey=WYQPLTPSGFELIB-JTQPXKBDSA-N"],"http://purl.obolibrary.org/obo#Synonym":["C27H34F2O7","(1R,2S,8S,10S,11S,14R,15S,17S)-14-[2-(acetyloxy)acetyl]-1,8-difluoro-17-hydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-14-yl butanoate"],"http://purl.obolibrary.org/obo#xref":["PDRhealth:http://www.pdrhealth.com/drugs/rx/rx-mono.aspx?contentFileNam","PubChem Substance:99443292","RxList:http://www.rxlist.com/durezol-drug.htm","Wikipedia:http://en.wikipedia.org/wiki/Difluprednate","PharmGKB:PA165958405","Drugs.com:http://www.drugs.com/durezol.html","ChemSpider:391990","PubChem Compound:443936"],"http://purl.obolibrary.org/obo#CASRN":["23674-86-4"],"https://data.bioontology.org/metadata/prefixIRI":["obo2:dinto_DB06781"],"http://purl.obolibrary.org/obo#SMILES":["[H][C@@]12CC[C@](OC(=O)CCC)(C(=O)COC(C)=O)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C"],"http://purl.obolibrary.org/obo/dinto_000499":["http://purl.obolibrary.org/obo/CHEBI_240107","http://purl.obolibrary.org/obo/CHEBI_5130","http://purl.obolibrary.org/obo/CHEBI_75922","http://purl.obolibrary.org/obo/dinto_DB00465","http://purl.obolibrary.org/obo/CHEBI_47381"],"http://www.w3.org/2000/01/rdf-schema#label":["difluprednate"],"http://purl.obolibrary.org/obo#InChI":["InChI=1S/C27H34F2O7/c1-5-6-23(34)36-26(22(33)14-35-15(2)30)10-8-17-18-12-20(28)19-11-16(31)7-9-24(19,3)27(18,29)21(32)13-25(17,26)4/h7,9,11,17-18,20-21,32H,5-6,8,10,12-14H2,1-4H3/t17-,18-,20-,21-,24-,25-,26-,27-/m0/s1"],"http://purl.obolibrary.org/obo#DBBrand":["durezol"],"http://www.w3.org/2000/01/rdf-schema#subClassOf":["http://purl.obolibrary.org/obo/dinto_000055"]},"@id":"http://purl.obolibrary.org/obo/dinto_DB06781","@type":"http://www.w3.org/2002/07/owl#Class","links":{"self":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_DB06781","ontology":"https://data.bioontology.org/ontologies/DINTO","children":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_DB06781/children","parents":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_DB06781/parents","descendants":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_DB06781/descendants","ancestors":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_DB06781/ancestors","instances":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_DB06781/instances","tree":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_DB06781/tree","notes":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_DB06781/notes","mappings":"https://data.bioontology.org/ontologies/DINTO/classes/http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_DB06781/mappings","ui":"http://bioportal.bioontology.org/ontologies/DINTO?p=classes&conceptid=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fdinto_DB06781","@context":{"self":"http://www.w3.org/2002/07/owl#Class","ontology":"http://data.bioontology.org/metadata/Ontology","children":"http://www.w3.org/2002/07/owl#Class","parents":"http://www.w3.org/2002/07/owl#Class","descendants":"http://www.w3.org/2002/07/owl#Class","ancestors":"http://www.w3.org/2002/07/owl#Class","instances":"http://data.bioontology.org/metadata/Instance","tree":"http://www.w3.org/2002/07/owl#Class","notes":"http://data.bioontology.org/metadata/Note","mappings":"http://data.bioontology.org/metadata/Mapping","ui":"http://www.w3.org/2002/07/owl#Class"}},"@context":{"@vocab":"http://data.bioontology.org/metadata/","label":"http://www.w3.org/2000/01/rdf-schema#label","prefLabel":"http://www.w3.org/2004/02/skos/core#prefLabel","prefLabelXl":"http://www.w3.org/2008/05/skos-xl#prefLabel","altLabelXl":"http://www.w3.org/2008/05/skos-xl#altLabel","hiddenLabelXl":"http://www.w3.org/2008/05/skos-xl#hiddenLabel","synonym":"http://www.w3.org/2004/02/skos/core#altLabel","definition":"http://www.w3.org/2004/02/skos/core#definition","obsolete":"http://www.w3.org/2002/07/owl#deprecated","notation":"http://www.w3.org/2004/02/skos/core#notation","prefixIRI":"http://data.bioontology.org/metadata/prefixIRI","parents":"http://www.w3.org/2000/01/rdf-schema##","subClassOf":"http://www.w3.org/2000/01/rdf-schema#subClassOf","semanticType":"http://bioportal.bioontology.org/ontologies/umls/hasSTY","cui":"http://bioportal.bioontology.org/ontologies/umls/cui","xref":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","inScheme":"http://www.w3.org/2004/02/skos/core#inScheme","created":"http://purl.org/dc/terms/created","modified":"http://purl.org/dc/terms/modified","@language":[]}}