{"id":"http://edamontology.org/topic_3974","prefLabel":"Epistasis","synonym":["Epistatic genetic interaction","Epistatic interactions"],"definition":["Epistasis can be defined as the ability of the genotype at one locus to supersede the phenotypic effect of a mutation at another locus. This interaction between genes can occur at different level: gene expression, protein levels, etc..."],"prefixIRI":"topic_3974","label":["Epistasis"],"subClassOf":["http://edamontology.org/topic_0625"],"parents":[{"id":"http://edamontology.org/topic_0625","prefLabel":"Genotype and phenotype","synonym":["Genotype-phenotype","Genotype-phenotype analysis","Genotype and phenotype resources","Phenotyping","Genotype","Genotyping","Phenotype"],"definition":["The study of genetic constitution of a living entity, such as an individual, and organism, a cell and so on, typically with respect to a particular observable phenotypic traits, or resources concerning such traits, which might be an aspect of biochemistry, physiology, morphology, anatomy, development and so on."],"prefixIRI":"topic_0625","label":["Genotype and phenotype"],"subClassOf":["http://edamontology.org/topic_3053"],"prefLabelXl":[],"altLabelXl":[],"hiddenLabelXl":[],"obsolete":false,"notation":null,"semanticType":[],"cui":[],"xref":null,"inScheme":[],"created":null,"modified":null,"@id":"http://edamontology.org/topic_0625","@type":"http://www.w3.org/2002/07/owl#Class","links":{"self":"https://data.bioontology.org/ontologies/EDAM/classes/http%3A%2F%2Fedamontology.org%2Ftopic_0625","ontology":"https://data.bioontology.org/ontologies/EDAM","children":"https://data.bioontology.org/ontologies/EDAM/classes/http%3A%2F%2Fedamontology.org%2Ftopic_0625/children","parents":"https://data.bioontology.org/ontologies/EDAM/classes/http%3A%2F%2Fedamontology.org%2Ftopic_0625/parents","descendants":"https://data.bioontology.org/ontologies/EDAM/classes/http%3A%2F%2Fedamontology.org%2Ftopic_0625/descendants","ancestors":"https://data.bioontology.org/ontologies/EDAM/classes/http%3A%2F%2Fedamontology.org%2Ftopic_0625/ancestors","instances":"https://data.bioontology.org/ontologies/EDAM/classes/http%3A%2F%2Fedamontology.org%2Ftopic_0625/instances","tree":"https://data.bioontology.org/ontologies/EDAM/classes/http%3A%2F%2Fedamontology.org%2Ftopic_0625/tree","notes":"https://data.bioontology.org/ontologies/EDAM/classes/http%3A%2F%2Fedamontology.org%2Ftopic_0625/notes","mappings":"https://data.bioontology.org/ontologies/EDAM/classes/http%3A%2F%2Fedamontology.org%2Ftopic_0625/mappings","ui":"http://bioportal.bioontology.org/ontologies/EDAM?p=classes&conceptid=http%3A%2F%2Fedamontology.org%2Ftopic_0625","@context":{"self":"http://www.w3.org/2002/07/owl#Class","ontology":"http://data.bioontology.org/metadata/Ontology","children":"http://www.w3.org/2002/07/owl#Class","parents":"http://www.w3.org/2002/07/owl#Class","descendants":"http://www.w3.org/2002/07/owl#Class","ancestors":"http://www.w3.org/2002/07/owl#Class","instances":"http://data.bioontology.org/metadata/Instance","tree":"http://www.w3.org/2002/07/owl#Class","notes":"http://data.bioontology.org/metadata/Note","mappings":"http://data.bioontology.org/metadata/Mapping","ui":"http://www.w3.org/2002/07/owl#Class"}},"@context":{"@vocab":"http://data.bioontology.org/metadata/","label":"http://www.w3.org/2000/01/rdf-schema#label","prefLabel":"http://www.w3.org/2004/02/skos/core#prefLabel","prefLabelXl":"http://www.w3.org/2008/05/skos-xl#prefLabel","altLabelXl":"http://www.w3.org/2008/05/skos-xl#altLabel","hiddenLabelXl":"http://www.w3.org/2008/05/skos-xl#hiddenLabel","synonym":"http://www.w3.org/2004/02/skos/core#altLabel","definition":"http://www.w3.org/2004/02/skos/core#definition","obsolete":"http://www.w3.org/2002/07/owl#deprecated","notation":"http://www.w3.org/2004/02/skos/core#notation","prefixIRI":"http://data.bioontology.org/metadata/prefixIRI","subClassOf":"http://www.w3.org/2000/01/rdf-schema#subClassOf","semanticType":"http://bioportal.bioontology.org/ontologies/umls/hasSTY","cui":"http://bioportal.bioontology.org/ontologies/umls/cui","xref":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","inScheme":"http://www.w3.org/2004/02/skos/core#inScheme","created":"http://purl.org/dc/terms/created","modified":"http://purl.org/dc/terms/modified","@language":[]}}],"obsolete":false,"notation":null,"semanticType":[],"cui":[],"xref":null,"inScheme":[],"created":null,"modified":null,"memberOf":[],"altLabelXl":[],"hiddenLabelXl":[],"prefLabelXl":[],"isInActiveScheme":[null],"isInActiveCollection":[],"properties":{"https://data.bioontology.org/metadata/def/prefLabel":["Epistasis"],"http://www.geneontology.org/formats/oboInOwl#hasExactSynonym":["Epistatic genetic interaction","Epistatic interactions"],"http://www.w3.org/2000/01/rdf-schema#seeAlso":["https://en.wikipedia.org/wiki/Epistasis","http://purl.bioontology.org/ontology/MSH/D004843"],"http://www.w3.org/1999/02/22-rdf-syntax-ns#type":["http://www.w3.org/2002/07/owl#Class"],"http://www.geneontology.org/formats/oboInOwl#hasDefinition":["Epistasis can be defined as the ability of the genotype at one locus to supersede the phenotypic effect of a mutation at another locus. This interaction between genes can occur at different level: gene expression, protein levels, etc..."],"http://www.geneontology.org/formats/oboInOwl#inSubset":["http://edamontology.org/bio","http://edamontology.org/topics"],"https://data.bioontology.org/metadata/prefixIRI":["topic_3974"],"http://www.w3.org/2000/01/rdf-schema#label":["Epistasis"],"http://edamontology.org/created_in":["1.25"],"http://www.w3.org/2000/01/rdf-schema#subClassOf":["http://edamontology.org/topic_0625"]},"@id":"http://edamontology.org/topic_3974","@type":"http://www.w3.org/2002/07/owl#Class","links":{"self":"https://data.bioontology.org/ontologies/EDAM/classes/http%3A%2F%2Fedamontology.org%2Ftopic_3974","ontology":"https://data.bioontology.org/ontologies/EDAM","children":"https://data.bioontology.org/ontologies/EDAM/classes/http%3A%2F%2Fedamontology.org%2Ftopic_3974/children","parents":"https://data.bioontology.org/ontologies/EDAM/classes/http%3A%2F%2Fedamontology.org%2Ftopic_3974/parents","descendants":"https://data.bioontology.org/ontologies/EDAM/classes/http%3A%2F%2Fedamontology.org%2Ftopic_3974/descendants","ancestors":"https://data.bioontology.org/ontologies/EDAM/classes/http%3A%2F%2Fedamontology.org%2Ftopic_3974/ancestors","instances":"https://data.bioontology.org/ontologies/EDAM/classes/http%3A%2F%2Fedamontology.org%2Ftopic_3974/instances","tree":"https://data.bioontology.org/ontologies/EDAM/classes/http%3A%2F%2Fedamontology.org%2Ftopic_3974/tree","notes":"https://data.bioontology.org/ontologies/EDAM/classes/http%3A%2F%2Fedamontology.org%2Ftopic_3974/notes","mappings":"https://data.bioontology.org/ontologies/EDAM/classes/http%3A%2F%2Fedamontology.org%2Ftopic_3974/mappings","ui":"http://bioportal.bioontology.org/ontologies/EDAM?p=classes&conceptid=http%3A%2F%2Fedamontology.org%2Ftopic_3974","@context":{"self":"http://www.w3.org/2002/07/owl#Class","ontology":"http://data.bioontology.org/metadata/Ontology","children":"http://www.w3.org/2002/07/owl#Class","parents":"http://www.w3.org/2002/07/owl#Class","descendants":"http://www.w3.org/2002/07/owl#Class","ancestors":"http://www.w3.org/2002/07/owl#Class","instances":"http://data.bioontology.org/metadata/Instance","tree":"http://www.w3.org/2002/07/owl#Class","notes":"http://data.bioontology.org/metadata/Note","mappings":"http://data.bioontology.org/metadata/Mapping","ui":"http://www.w3.org/2002/07/owl#Class"}},"@context":{"@vocab":"http://data.bioontology.org/metadata/","label":"http://www.w3.org/2000/01/rdf-schema#label","prefLabel":"http://www.w3.org/2004/02/skos/core#prefLabel","prefLabelXl":"http://www.w3.org/2008/05/skos-xl#prefLabel","altLabelXl":"http://www.w3.org/2008/05/skos-xl#altLabel","hiddenLabelXl":"http://www.w3.org/2008/05/skos-xl#hiddenLabel","synonym":"http://www.w3.org/2004/02/skos/core#altLabel","definition":"http://www.w3.org/2004/02/skos/core#definition","obsolete":"http://www.w3.org/2002/07/owl#deprecated","notation":"http://www.w3.org/2004/02/skos/core#notation","prefixIRI":"http://data.bioontology.org/metadata/prefixIRI","parents":"http://www.w3.org/2000/01/rdf-schema##","subClassOf":"http://www.w3.org/2000/01/rdf-schema#subClassOf","semanticType":"http://bioportal.bioontology.org/ontologies/umls/hasSTY","cui":"http://bioportal.bioontology.org/ontologies/umls/cui","xref":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","inScheme":"http://www.w3.org/2004/02/skos/core#inScheme","created":"http://purl.org/dc/terms/created","modified":"http://purl.org/dc/terms/modified","@language":[]}}