<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
55
</numberChangedClasses>
<numberNewClasses>
47
</numberNewClasses>
<numberDeletedClasses>
24
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://edamontology.org/operation_0331</classIRI>
<classLabel>Protein modelling (mutation)</classLabel>
<deletedAxiom>&apos;Protein modelling (mutation)&apos; SubClassOf &apos;Protein modelling&apos;</deletedAxiom>
<newAxiom>&apos;Protein modelling (mutation)&apos; SubClassOf &apos;Prediction and recognition&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/operation_0389</classIRI>
<classLabel>Protein-nucleic acid binding site analysis</classLabel>
<deletedAxiom>&apos;Protein-nucleic acid binding site analysis&apos; SubClassOf &apos;Protein interaction analysis&apos;</deletedAxiom>
<newAxiom>&apos;Protein-nucleic acid binding site analysis&apos; SubClassOf &apos;Protein function prediction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/operation_0397</classIRI>
<classLabel>Ramachandran plot validation</classLabel>
<deletedAxiom>&apos;Ramachandran plot validation&apos; SubClassOf &apos;Protein geometry validation&apos;</deletedAxiom>
<deletedAxiom>&apos;Ramachandran plot validation&apos; SubClassOf &apos;has input&apos; some &apos;Ramachandran plot&apos;</deletedAxiom>
<deletedAxiom>&apos;Ramachandran plot validation&apos; SubClassOf &apos;has output&apos; some &apos;Protein structural quality report&apos;</deletedAxiom>
<newAxiom>&apos;Ramachandran plot validation&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/operation_0365</classIRI>
<classLabel>Nucleic acid restriction digest</classLabel>
<deletedAxiom>&apos;Nucleic acid restriction digest&apos; SubClassOf &apos;Sequence generation (nucleic acid)&apos;</deletedAxiom>
<newAxiom>&apos;Nucleic acid restriction digest&apos; SubClassOf &apos;Sequence generation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/operation_0366</classIRI>
<classLabel>Protein sequence cleavage</classLabel>
<deletedAxiom>&apos;Protein sequence cleavage&apos; SubClassOf &apos;Sequence generation (protein)&apos;</deletedAxiom>
<newAxiom>&apos;Protein sequence cleavage&apos; SubClassOf &apos;Sequence generation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/operation_0363</classIRI>
<classLabel>Nucleic acid sequence reverse and complement</classLabel>
<deletedAxiom>&apos;Nucleic acid sequence reverse and complement&apos; SubClassOf &apos;Sequence generation (nucleic acid)&apos;</deletedAxiom>
<newAxiom>&apos;Nucleic acid sequence reverse and complement&apos; SubClassOf &apos;Sequence generation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_2399</classIRI>
<classLabel>Gene transcriptional features report</classLabel>
<deletedAxiom>&apos;Gene transcriptional features report&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_2397</classIRI>
<classLabel>Gene features report (exon)</classLabel>
<deletedAxiom>&apos;Gene features report (exon)&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/operation_2963</classIRI>
<classLabel>Codon usage bias plotting</classLabel>
<deletedAxiom>&apos;Codon usage bias plotting&apos; SubClassOf &apos;Sequence visualisation&apos;</deletedAxiom>
<deletedAxiom>&apos;Codon usage bias plotting&apos; SubClassOf &apos;has output&apos; some &apos;Codon usage bias plot&apos;</deletedAxiom>
<deletedAxiom>&apos;Codon usage bias plotting&apos; SubClassOf &apos;Codon usage bias calculation&apos;</deletedAxiom>
<newAxiom>&apos;Codon usage bias plotting&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/operation_2949</classIRI>
<classLabel>Protein interaction analysis</classLabel>
<deletedAxiom>&apos;Protein interaction analysis&apos; SubClassOf &apos;Protein function analysis&apos;</deletedAxiom>
<newAxiom>&apos;Protein interaction analysis&apos; SubClassOf &apos;Protein function prediction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/operation_0478</classIRI>
<classLabel>Molecular docking</classLabel>
<deletedAxiom>&apos;Molecular docking&apos; SubClassOf &apos;Protein interaction prediction&apos;</deletedAxiom>
<newAxiom>&apos;Molecular docking&apos; SubClassOf &apos;Protein function prediction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/operation_1778</classIRI>
<classLabel>Protein function comparison</classLabel>
<deletedAxiom>&apos;Protein function comparison&apos; SubClassOf &apos;Protein function analysis&apos;</deletedAxiom>
<newAxiom>&apos;Protein function comparison&apos; SubClassOf &apos;Protein function prediction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/operation_1777</classIRI>
<classLabel>Protein function prediction</classLabel>
<deletedAxiom>&apos;Protein function prediction&apos; SubClassOf &apos;Protein function analysis&apos;</deletedAxiom>
<newAxiom>&apos;Protein function prediction&apos; SubClassOf &apos;Analysis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/topic_2844</classIRI>
<classLabel>Structural clustering</classLabel>
<deletedAxiom>&apos;Structural clustering&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</deletedAxiom>
<newAxiom>&apos;Structural clustering&apos; SubClassOf &apos;Clustering&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/topic_0176</classIRI>
<classLabel>Molecular dynamics</classLabel>
<newAxiom>&apos;Molecular dynamics&apos; SubClassOf http://edamontology.org/topic_3892</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/operation_0418</classIRI>
<classLabel>Protein signal peptide detection</classLabel>
<deletedAxiom>&apos;Protein signal peptide detection&apos; SubClassOf &apos;Protein subcellular localisation prediction&apos;</deletedAxiom>
<newAxiom>&apos;Protein signal peptide detection&apos; SubClassOf &apos;Protein function prediction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/operation_3185</classIRI>
<classLabel>Base-calling</classLabel>
<deletedAxiom>&apos;Base-calling&apos; SubClassOf &apos;Sequence generation (nucleic acid)&apos;</deletedAxiom>
<newAxiom>&apos;Base-calling&apos; SubClassOf &apos;Sequence generation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/operation_0252</classIRI>
<classLabel>Peptide immunogenicity prediction</classLabel>
<deletedAxiom>&apos;Peptide immunogenicity prediction&apos; SubClassOf &apos;Protein interaction prediction&apos;</deletedAxiom>
<newAxiom>&apos;Peptide immunogenicity prediction&apos; SubClassOf &apos;Protein function prediction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/format_1475</classIRI>
<classLabel>PDB database entry format</classLabel>
<newAxiom>&apos;PDB database entry format&apos; SubClassOf &apos;is format of&apos; some http://edamontology.org/data_3870</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/operation_3280</classIRI>
<classLabel>Named-entity and concept recognition</classLabel>
<deletedAxiom>&apos;Named-entity and concept recognition&apos; SubClassOf &apos;Text mining&apos;</deletedAxiom>
<newAxiom>&apos;Named-entity and concept recognition&apos; SubClassOf http://edamontology.org/operation_3907</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_1456</classIRI>
<classLabel>Protein features report (membrane regions)</classLabel>
<deletedAxiom>&apos;Protein features report (membrane regions)&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/format_3590</classIRI>
<classLabel>hdf5</classLabel>
<newAxiom>&apos;hdf5&apos; SubClassOf http://edamontology.org/format_3867</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/operation_2513</classIRI>
<classLabel>Sequence generation (nucleic acid)</classLabel>
<deletedAxiom>&apos;Sequence generation (nucleic acid)&apos; SubClassOf &apos;Sequence generation&apos;</deletedAxiom>
<newAxiom>&apos;Sequence generation (nucleic acid)&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/operation_2514</classIRI>
<classLabel>Sequence generation (protein)</classLabel>
<deletedAxiom>&apos;Sequence generation (protein)&apos; SubClassOf &apos;Sequence generation&apos;</deletedAxiom>
<newAxiom>&apos;Sequence generation (protein)&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/operation_2575</classIRI>
<classLabel>Protein binding site prediction</classLabel>
<deletedAxiom>&apos;Protein binding site prediction&apos; SubClassOf &apos;Protein interaction prediction&apos;</deletedAxiom>
<newAxiom>&apos;Protein binding site prediction&apos; SubClassOf &apos;Protein function prediction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_3275</classIRI>
<classLabel>Phenotype name</classLabel>
<deletedAxiom>&apos;Phenotype name&apos; SubClassOf &apos;Identifier (by type of data)&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_0922</classIRI>
<classLabel>Nucleic acid features report (primers)</classLabel>
<deletedAxiom>&apos;Nucleic acid features report (primers)&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_2754</classIRI>
<classLabel>Gene features report (intron)</classLabel>
<deletedAxiom>&apos;Gene features report (intron)&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_2869</classIRI>
<classLabel>Nucleic acid features report (RFLP)</classLabel>
<deletedAxiom>&apos;Nucleic acid features report (RFLP)&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_2867</classIRI>
<classLabel>Nucleic acid features report (VNTR)</classLabel>
<deletedAxiom>&apos;Nucleic acid features report (VNTR)&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_2868</classIRI>
<classLabel>Nucleic acid features report (microsatellite)</classLabel>
<deletedAxiom>&apos;Nucleic acid features report (microsatellite)&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_2885</classIRI>
<classLabel>Nucleic acid features report (polymorphism)</classLabel>
<deletedAxiom>&apos;Nucleic acid features report (polymorphism)&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_2533</classIRI>
<classLabel>Nucleic acid features report (mutation)</classLabel>
<deletedAxiom>&apos;Nucleic acid features report (mutation)&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/operation_3644</classIRI>
<classLabel>de Novo sequencing</classLabel>
<deletedAxiom>&apos;de Novo sequencing&apos; SubClassOf &apos;Sequence generation (protein)&apos;</deletedAxiom>
<newAxiom>&apos;de Novo sequencing&apos; SubClassOf &apos;Sequence generation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_3022</classIRI>
<classLabel>NCBI genetic code ID</classLabel>
<deletedAxiom>&apos;NCBI genetic code ID&apos; SubClassOf &apos;Identifier (by type of data)&apos;</deletedAxiom>
<newAxiom>&apos;NCBI genetic code ID&apos; SubClassOf &apos;Genetic code identifier&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/operation_2414</classIRI>
<classLabel>Protein function analysis</classLabel>
<deletedAxiom>&apos;Protein function analysis&apos; SubClassOf &apos;Analysis&apos;</deletedAxiom>
<deletedAxiom>&apos;Protein function analysis&apos; SubClassOf &apos;has output&apos; some &apos;Protein report&apos;</deletedAxiom>
<deletedAxiom>&apos;Protein function analysis&apos; SubClassOf &apos;has topic&apos; some &apos;Proteins&apos;</deletedAxiom>
<newAxiom>&apos;Protein function analysis&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/operation_2422</classIRI>
<classLabel>Data retrieval</classLabel>
<newAxiom>&apos;Data retrieval&apos; SubClassOf http://edamontology.org/operation_3908</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/format_3650</classIRI>
<classLabel>netCDF</classLabel>
<newAxiom>&apos;netCDF&apos; SubClassOf http://edamontology.org/format_3867</newAxiom>
<newAxiom>&apos;netCDF&apos; SubClassOf &apos;Binary format&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/operation_2499</classIRI>
<classLabel>Splicing model analysis</classLabel>
<deletedAxiom>&apos;Splicing model analysis&apos; SubClassOf &apos;Sequence analysis&apos;</deletedAxiom>
<newAxiom>&apos;Splicing model analysis&apos; SubClassOf &apos;Nucleic acid sequence analysis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_3118</classIRI>
<classLabel>Protein features report (topological domains)</classLabel>
<deletedAxiom>&apos;Protein features report (topological domains)&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/operation_2492</classIRI>
<classLabel>Protein interaction prediction</classLabel>
<deletedAxiom>&apos;Protein interaction prediction&apos; SubClassOf &apos;Protein function prediction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_3125</classIRI>
<classLabel>Nucleic acid features report (binding)</classLabel>
<deletedAxiom>&apos;Nucleic acid features report (binding)&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_3126</classIRI>
<classLabel>Nucleic acid repeats (report)</classLabel>
<deletedAxiom>&apos;Nucleic acid repeats (report)&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_3127</classIRI>
<classLabel>Nucleic acid features report (replication and recombination)</classLabel>
<deletedAxiom>&apos;Nucleic acid features report (replication and recombination)&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/operation_2464</classIRI>
<classLabel>Protein-protein interaction prediction</classLabel>
<deletedAxiom>&apos;Protein-protein interaction prediction&apos; SubClassOf &apos;Protein interaction prediction&apos;</deletedAxiom>
<newAxiom>&apos;Protein-protein interaction prediction&apos; SubClassOf &apos;Protein binding site prediction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_3123</classIRI>
<classLabel>Nucleic acid features report (expression signal)</classLabel>
<deletedAxiom>&apos;Nucleic acid features report (expression signal)&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_3139</classIRI>
<classLabel>Nucleic acid features report (STS)</classLabel>
<deletedAxiom>&apos;Nucleic acid features report (STS)&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_3135</classIRI>
<classLabel>Nucleic acid features report (signal or transit peptide)</classLabel>
<deletedAxiom>&apos;Nucleic acid features report (signal or transit peptide)&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_1305</classIRI>
<classLabel>Nucleic acid features report (restriction sites)</classLabel>
<deletedAxiom>&apos;Nucleic acid features report (restriction sites)&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_1304</classIRI>
<classLabel>Nucleic acid features report (CpG island and isochore)</classLabel>
<deletedAxiom>&apos;Nucleic acid features report (CpG island and isochore)&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_1308</classIRI>
<classLabel>Nucleic acid features report (matrix/scaffold attachment sites)</classLabel>
<deletedAxiom>&apos;Nucleic acid features report (matrix/scaffold attachment sites)&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_1307</classIRI>
<classLabel>Nucleic acid features report (splice sites)</classLabel>
<deletedAxiom>&apos;Nucleic acid features report (splice sites)&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_1302</classIRI>
<classLabel>Nucleic acid features report (PolyA signal or site)</classLabel>
<deletedAxiom>&apos;Nucleic acid features report (PolyA signal or site)&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_1312</classIRI>
<classLabel>Nucleic acid features report (promoters)</classLabel>
<deletedAxiom>&apos;Nucleic acid features report (promoters)&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://edamontology.org/data_1311</classIRI>
<classLabel>Gene features report (operon)</classLabel>
<deletedAxiom>&apos;Gene features report (operon)&apos; SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</deletedAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://edamontology.org/format_3909</classIRI>
<classLabel>BpForms</classLabel>
<newAxiom>'BpForms' SubClassOf 'Raw sequence format'</newAxiom>
<newAxiom>'BpForms' SubClassOf 'is format of' some 'Sequence features'</newAxiom>
<newAxiom>'BpForms' SubClassOf 'Chemical formula format'</newAxiom>
<newAxiom>'BpForms' SubClassOf 'Textual format'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/format_3906</classIRI>
<classLabel>NMReDATA</classLabel>
<newAxiom>'NMReDATA' SubClassOf 'NMR data format'</newAxiom>
<newAxiom>'NMReDATA' SubClassOf 'Textual format'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/format_3911</classIRI>
<classLabel>msh</classLabel>
<newAxiom>'msh' SubClassOf 'Raw sequence format'</newAxiom>
<newAxiom>'msh' SubClassOf 'is format of' some 'Sequence checksum'</newAxiom>
<newAxiom>'msh' SubClassOf 'Binary format'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/format_3910</classIRI>
<classLabel>trr</classLabel>
<newAxiom>'trr' SubClassOf 'Textual format'</newAxiom>
<newAxiom>'trr' SubClassOf 'Tertiary structure format'</newAxiom>
<newAxiom>'trr' SubClassOf 'Trajectory format (text)'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/format_3882</classIRI>
<classLabel>PSF</classLabel>
<newAxiom>'PSF' SubClassOf 'Topology format'</newAxiom>
<newAxiom>'PSF' SubClassOf 'Tertiary structure format'</newAxiom>
<newAxiom>'PSF' SubClassOf 'Textual format'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/format_3881</classIRI>
<classLabel>AMBER top</classLabel>
<newAxiom>'AMBER top' SubClassOf 'Topology format'</newAxiom>
<newAxiom>'AMBER top' SubClassOf 'Tertiary structure format'</newAxiom>
<newAxiom>'AMBER top' SubClassOf 'Textual format'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/format_3884</classIRI>
<classLabel>FF parameter format</classLabel>
<newAxiom>'FF parameter format' SubClassOf 'is format of' some 'Topology data'</newAxiom>
<newAxiom>'FF parameter format' SubClassOf 'Format (by type of data)'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/format_3883</classIRI>
<classLabel>GROMACS itp</classLabel>
<newAxiom>'GROMACS itp' SubClassOf 'Tertiary structure format'</newAxiom>
<newAxiom>'GROMACS itp' SubClassOf 'Textual format'</newAxiom>
<newAxiom>'GROMACS itp' SubClassOf 'Topology format'</newAxiom>
<newAxiom>'GROMACS itp' SubClassOf 'FF parameter format'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/format_3880</classIRI>
<classLabel>GROMACS top</classLabel>
<newAxiom>'GROMACS top' SubClassOf 'Textual format'</newAxiom>
<newAxiom>'GROMACS top' SubClassOf 'Tertiary structure format'</newAxiom>
<newAxiom>'GROMACS top' SubClassOf 'Topology format'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/format_3889</classIRI>
<classLabel>AMBER off</classLabel>
<newAxiom>'AMBER off' SubClassOf 'Textual format'</newAxiom>
<newAxiom>'AMBER off' SubClassOf 'FF parameter format'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/format_3886</classIRI>
<classLabel>RST</classLabel>
<newAxiom>'RST' SubClassOf 'Textual format'</newAxiom>
<newAxiom>'RST' SubClassOf 'Tertiary structure format'</newAxiom>
<newAxiom>'RST' SubClassOf 'Trajectory format (text)'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/format_3885</classIRI>
<classLabel>BinPos</classLabel>
<newAxiom>'BinPos' SubClassOf 'Trajectory format (binary)'</newAxiom>
<newAxiom>'BinPos' SubClassOf 'Binary format'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/format_3888</classIRI>
<classLabel>AMBER frcmod</classLabel>
<newAxiom>'AMBER frcmod' SubClassOf 'FF parameter format'</newAxiom>
<newAxiom>'AMBER frcmod' SubClassOf 'Textual format'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/format_3887</classIRI>
<classLabel>CHARMM rtf</classLabel>
<newAxiom>'CHARMM rtf' SubClassOf 'Textual format'</newAxiom>
<newAxiom>'CHARMM rtf' SubClassOf 'Tertiary structure format'</newAxiom>
<newAxiom>'CHARMM rtf' SubClassOf 'Topology format'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/format_3873</classIRI>
<classLabel>HDF</classLabel>
<newAxiom>'HDF' SubClassOf 'Binary format'</newAxiom>
<newAxiom>'HDF' SubClassOf 'Trajectory format (binary)'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/format_3879</classIRI>
<classLabel>Topology format</classLabel>
<newAxiom>'Topology format' SubClassOf 'Format (by type of data)'</newAxiom>
<newAxiom>'Topology format' SubClassOf 'is format of' some 'Topology data'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/format_3878</classIRI>
<classLabel>mdcrd</classLabel>
<newAxiom>'mdcrd' SubClassOf 'Textual format'</newAxiom>
<newAxiom>'mdcrd' SubClassOf 'Tertiary structure format'</newAxiom>
<newAxiom>'mdcrd' SubClassOf 'Trajectory format (text)'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/format_3875</classIRI>
<classLabel>XTC</classLabel>
<newAxiom>'XTC' SubClassOf 'Binary format'</newAxiom>
<newAxiom>'XTC' SubClassOf 'Trajectory format (binary)'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/format_3874</classIRI>
<classLabel>PCAzip</classLabel>
<newAxiom>'PCAzip' SubClassOf 'Trajectory format (binary)'</newAxiom>
<newAxiom>'PCAzip' SubClassOf 'Binary format'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/format_3877</classIRI>
<classLabel>XYZ</classLabel>
<newAxiom>'XYZ' SubClassOf 'Tertiary structure format'</newAxiom>
<newAxiom>'XYZ' SubClassOf 'Textual format'</newAxiom>
<newAxiom>'XYZ' SubClassOf 'Trajectory format (text)'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/format_3876</classIRI>
<classLabel>TNG</classLabel>
<newAxiom>'TNG' SubClassOf 'Trajectory format (binary)'</newAxiom>
<newAxiom>'TNG' SubClassOf 'Binary format'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/format_3868</classIRI>
<classLabel>Trajectory format (text)</classLabel>
<newAxiom>'Trajectory format (text)' SubClassOf 'Trajectory format'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/format_3867</classIRI>
<classLabel>Trajectory format (binary)</classLabel>
<newAxiom>'Trajectory format (binary)' SubClassOf 'Trajectory format'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/format_3866</classIRI>
<classLabel>Trajectory format</classLabel>
<newAxiom>'Trajectory format' SubClassOf 'is format of' some 'Trajectory data'</newAxiom>
<newAxiom>'Trajectory format' SubClassOf 'Format (by type of data)'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/topic_3912</classIRI>
<classLabel>Genetic engineering</classLabel>
<newAxiom>'Genetic engineering' SubClassOf 'Genetics'</newAxiom>
<newAxiom>'Genetic engineering' SubClassOf 'Biotechnology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/topic_3895</classIRI>
<classLabel>Synthetic biology</classLabel>
<newAxiom>'Synthetic biology' SubClassOf 'Biotechnology'</newAxiom>
<newAxiom>'Synthetic biology' SubClassOf 'Biology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/topic_3892</classIRI>
<classLabel>Biomolecular simulation</classLabel>
<newAxiom>'Biomolecular simulation' SubClassOf 'Computational biology'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/operation_3899</classIRI>
<classLabel>Protein-protein docking</classLabel>
<newAxiom>'Protein-protein docking' SubClassOf 'has output' some 'Protein-ligand complex'</newAxiom>
<newAxiom>'Protein-protein docking' SubClassOf 'has topic' some 'Protein interactions'</newAxiom>
<newAxiom>'Protein-protein docking' SubClassOf 'Molecular docking'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/operation_3898</classIRI>
<classLabel>Metal-binding site prediction</classLabel>
<newAxiom>'Metal-binding site prediction' SubClassOf 'Binding site prediction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/operation_3897</classIRI>
<classLabel>Ligand-binding site prediction</classLabel>
<newAxiom>'Ligand-binding site prediction' SubClassOf 'Binding site prediction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/operation_3896</classIRI>
<classLabel>Active site prediction</classLabel>
<newAxiom>'Active site prediction' SubClassOf 'Binding site prediction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/operation_3891</classIRI>
<classLabel>Essential dynamics</classLabel>
<newAxiom>'Essential dynamics' SubClassOf 'Simulation analysis'</newAxiom>
<newAxiom>'Essential dynamics' SubClassOf 'Nucleic acid structure analysis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/operation_3890</classIRI>
<classLabel>Trajectory visualization</classLabel>
<newAxiom>'Trajectory visualization' SubClassOf 'Structure visualisation'</newAxiom>
<newAxiom>'Trajectory visualization' SubClassOf 'has output' some 'Helical wheel'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/operation_3894</classIRI>
<classLabel>DNA profiling</classLabel>
<newAxiom>'DNA profiling' SubClassOf 'Nucleic acid sequence analysis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/operation_3893</classIRI>
<classLabel>Forcefield parameterisation</classLabel>
<newAxiom>'Forcefield parameterisation' SubClassOf 'Modelling and simulation'</newAxiom>
<newAxiom>'Forcefield parameterisation' SubClassOf 'has output' some 'DNA substitution model'</newAxiom>
<newAxiom>'Forcefield parameterisation' SubClassOf 'has topic' some 'Phylogeny'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/operation_3903</classIRI>
<classLabel>DNA binding site prediction</classLabel>
<newAxiom>'DNA binding site prediction' SubClassOf 'Nucleic acids-binding site prediction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/operation_3902</classIRI>
<classLabel>RNA binding site prediction</classLabel>
<newAxiom>'RNA binding site prediction' SubClassOf 'Nucleic acids-binding site prediction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/operation_3901</classIRI>
<classLabel>RNA-binding protein prediction</classLabel>
<newAxiom>'RNA-binding protein prediction' SubClassOf 'Protein-nucleic acid interaction analysis'</newAxiom>
<newAxiom>'RNA-binding protein prediction' SubClassOf 'has topic' some 'Protein interactions'</newAxiom>
<newAxiom>'RNA-binding protein prediction' SubClassOf 'has output' some 'Protein interaction data'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/operation_3900</classIRI>
<classLabel>DNA-binding protein prediction</classLabel>
<newAxiom>'DNA-binding protein prediction' SubClassOf 'Protein-nucleic acid interaction analysis'</newAxiom>
<newAxiom>'DNA-binding protein prediction' SubClassOf 'has topic' some 'Protein interactions'</newAxiom>
<newAxiom>'DNA-binding protein prediction' SubClassOf 'has output' some 'Protein interaction data'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/operation_3907</classIRI>
<classLabel>Information extraction</classLabel>
<newAxiom>'Information extraction' SubClassOf 'Text mining'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/operation_3904</classIRI>
<classLabel>Protein disorder prediction</classLabel>
<newAxiom>'Protein disorder prediction' SubClassOf 'has topic' some 'Microbiology'</newAxiom>
<newAxiom>'Protein disorder prediction' SubClassOf 'Prediction and recognition'</newAxiom>
<newAxiom>'Protein disorder prediction' SubClassOf 'Protein feature detection'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/operation_3908</classIRI>
<classLabel>Information retrieval</classLabel>
<newAxiom>'Information retrieval' SubClassOf 'Text mining'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/data_3869</classIRI>
<classLabel>Simulation</classLabel>
<newAxiom>'Simulation' SubClassOf 'Data'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/data_3870</classIRI>
<classLabel>Trajectory data</classLabel>
<newAxiom>'Trajectory data' SubClassOf 'Simulation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/data_3871</classIRI>
<classLabel>Forcefield parameters</classLabel>
<newAxiom>'Forcefield parameters' SubClassOf 'Simulation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/data_3872</classIRI>
<classLabel>Topology data</classLabel>
<newAxiom>'Topology data' SubClassOf 'Simulation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://edamontology.org/data_3905</classIRI>
<classLabel>Histogram</classLabel>
<newAxiom>'Histogram' SubClassOf 'Plot'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
<deletedClass>
<classIRI>http://edamontology.org/data_2399</classIRI>
<classLabel>Gene transcriptional features report</classLabel>
<newAxiom>'Gene transcriptional features report' SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://edamontology.org/data_2397</classIRI>
<classLabel>Gene features report (exon)</classLabel>
<newAxiom>'Gene features report (exon)' SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://edamontology.org/data_1456</classIRI>
<classLabel>Protein features report (membrane regions)</classLabel>
<newAxiom>'Protein features report (membrane regions)' SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://edamontology.org/data_0922</classIRI>
<classLabel>Nucleic acid features report (primers)</classLabel>
<newAxiom>'Nucleic acid features report (primers)' SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://edamontology.org/data_2754</classIRI>
<classLabel>Gene features report (intron)</classLabel>
<newAxiom>'Gene features report (intron)' SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://edamontology.org/data_2869</classIRI>
<classLabel>Nucleic acid features report (RFLP)</classLabel>
<newAxiom>'Nucleic acid features report (RFLP)' SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://edamontology.org/data_2867</classIRI>
<classLabel>Nucleic acid features report (VNTR)</classLabel>
<newAxiom>'Nucleic acid features report (VNTR)' SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://edamontology.org/data_2868</classIRI>
<classLabel>Nucleic acid features report (microsatellite)</classLabel>
<newAxiom>'Nucleic acid features report (microsatellite)' SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://edamontology.org/data_2885</classIRI>
<classLabel>Nucleic acid features report (polymorphism)</classLabel>
<newAxiom>'Nucleic acid features report (polymorphism)' SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://edamontology.org/data_2533</classIRI>
<classLabel>Nucleic acid features report (mutation)</classLabel>
<newAxiom>'Nucleic acid features report (mutation)' SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://edamontology.org/data_3118</classIRI>
<classLabel>Protein features report (topological domains)</classLabel>
<newAxiom>'Protein features report (topological domains)' SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://edamontology.org/data_3125</classIRI>
<classLabel>Nucleic acid features report (binding)</classLabel>
<newAxiom>'Nucleic acid features report (binding)' SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://edamontology.org/data_3126</classIRI>
<classLabel>Nucleic acid repeats (report)</classLabel>
<newAxiom>'Nucleic acid repeats (report)' SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://edamontology.org/data_3127</classIRI>
<classLabel>Nucleic acid features report (replication and recombination)</classLabel>
<newAxiom>'Nucleic acid features report (replication and recombination)' SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://edamontology.org/data_3123</classIRI>
<classLabel>Nucleic acid features report (expression signal)</classLabel>
<newAxiom>'Nucleic acid features report (expression signal)' SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://edamontology.org/data_3139</classIRI>
<classLabel>Nucleic acid features report (STS)</classLabel>
<newAxiom>'Nucleic acid features report (STS)' SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://edamontology.org/data_3135</classIRI>
<classLabel>Nucleic acid features report (signal or transit peptide)</classLabel>
<newAxiom>'Nucleic acid features report (signal or transit peptide)' SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://edamontology.org/data_1305</classIRI>
<classLabel>Nucleic acid features report (restriction sites)</classLabel>
<newAxiom>'Nucleic acid features report (restriction sites)' SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://edamontology.org/data_1304</classIRI>
<classLabel>Nucleic acid features report (CpG island and isochore)</classLabel>
<newAxiom>'Nucleic acid features report (CpG island and isochore)' SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://edamontology.org/data_1308</classIRI>
<classLabel>Nucleic acid features report (matrix/scaffold attachment sites)</classLabel>
<newAxiom>'Nucleic acid features report (matrix/scaffold attachment sites)' SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://edamontology.org/data_1307</classIRI>
<classLabel>Nucleic acid features report (splice sites)</classLabel>
<newAxiom>'Nucleic acid features report (splice sites)' SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://edamontology.org/data_1302</classIRI>
<classLabel>Nucleic acid features report (PolyA signal or site)</classLabel>
<newAxiom>'Nucleic acid features report (PolyA signal or site)' SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://edamontology.org/data_1312</classIRI>
<classLabel>Nucleic acid features report (promoters)</classLabel>
<newAxiom>'Nucleic acid features report (promoters)' SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://edamontology.org/data_1311</classIRI>
<classLabel>Gene features report (operon)</classLabel>
<newAxiom>'Gene features report (operon)' SubClassOf http://www.w3.org/2002/07/owl#DeprecatedClass</newAxiom>
</deletedClass>
</deletedClasses>
</diffReport>