Class ID,Preferred Label,Synonyms,Definitions,Obsolete,CUI,Semantic Types,Parents,2D boundary of,achieves_planned_objective,adjacent to,alternative term,antisymmetric property,bearer of,BFO CLIF specification label,BFO OWL specification label,binding by protein,bound_to,ChIP-seq binding at,concretizes,contains process,Contributor,Coverage,Creator,curator note,Date,definition,definition source,denotes,derives from,derives into,Description,editor note,editor preferred term,elucidation,example of usage,expand assertion to,expand expression to,FGED alternative term,first order logic expression,Format,function of,has 2D boundary,has associated axiom(fol),has associated axiom(nl),has axiom label,has category label,has coordinate unit label,has curation status,has disposition to bind,has function,has grain,has ID digit count,has ID policy for,has ID prefix,has ID range allocated to,has measurement datum,has measurement unit label,has measurement value,has member,has obsolescence reason,has organization member,has part,has participant,has performer,has quality,has role,has specified value,has time stamp,has value specification,has x coordinate value,has y coordinate value,has z coordinate value,has_feature_value,has_specified_input,has_specified_output,has_supplier,http://data.bioontology.org/metadata/obo/part_of,http://data.bioontology.org/metadata/prefixIRI,http://data.bioontology.org/metadata/treeView,http://protege.stanford.edu/plugins/owl/protege#defaultLanguage,http://purl.obolibrary.org/obo/EGO_0000000014,http://purl.org/dc/elements/1.1/license,http://purl.org/dc/elements/1.1/member,http://usefulinc.com/ns/doap#browse,http://usefulinc.com/ns/doap#bug-database,http://usefulinc.com/ns/doap#file-release,http://usefulinc.com/ns/doap#homepage,http://usefulinc.com/ns/doap#mailing-list,http://usefulinc.com/ns/doap#release,http://usefulinc.com/ns/doap#repository,http://usefulinc.com/ns/doap#revision,http://usefulinc.com/ns/doap#wiki,http://www.ebi.ac.uk/cellline/definition,http://www.ebi.ac.uk/cellline/definition_editor,http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty,http://www.w3.org/2000/01/rdf-schema#comment,http://www.w3.org/2000/01/rdf-schema#isDefinedBy,http://www.w3.org/2000/01/rdf-schema#seeAlso,http://www.w3.org/2002/07/owl#versionInfo,http://xmlns.com/foaf/0.1/homepage,http://xmlns.com/foaf/0.1/page,IEDB alternative term,immediately preceded by,immediately precedes,imported from,in branch,inheres in,is about,is allocated id range,is concretized as,is denotator type,is duration of,is grain of,is member of organization,is quality measured as,is quality measurement of,is quality specification of,is_manufactured_by,is_proxy_for,is_specified_input_of,is_specified_output_of,is_supported_by_data,ISA alternative term,label,Language,located in,location of,member of,mentions,NIAID GSCID-BRC alternative term,objective_achieved_by,OBO foundry unique label,obsolete_describes,obsolete_has_function,obsolete_has_quality,obsolete_has_role,obsolete_is_concretization_of,obsolete_is_concretized_as,obsolete_is_described_by,obsolete_is_realized_by,obsolete_materially denotes,obsolete_realizes,obsolete_represents,obsolete_results_from,obsolete_specifically denotes,obsoleted_has_specified_input_information,obsoleted_has_specified_output_information,obsoleted_is_device_for,obsoleted_is_reagent_in,obsoleted_is_specified_information_intput_of,obsoleted_is_specified_information_output_of,obsoleted_utilizes_device,obsoleted_utilizes_reagent,occurs in,part of,participates in,preceded by,preceded by,precedes,precedes,process is result of,provides_service_consumer_with,Publisher,quality is specified as,quality of,realized in,realized in cell,realizes,Relation,Resource Identifier,Resource Type,retired from use as of,Rights Management,role of,shorthand,Source,specifies value of,starts,Subject and Keywords,supplies,surrounded by,temporal interpretation,temporal relation,term editor,term replaced by,Title
http://purl.obolibrary.org/obo/OBI_0001002,Faraday cage,Faraday shield,"A device formed by conducting material or by a mesh of such material, that blocks out external static electric fields.",false,,,http://purl.obolibrary.org/obo/OBI_0001034,,,,Faraday shield,,,,,,,,,,,,,isolation function? HP,,"A device formed by conducting material or by a mesh of such material, that blocks out external static electric fields.",Wikipedia http://en.wikipedia.org/wiki/Faraday_cage,,,,,,Faraday cage,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000401,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001002,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Faraday cage,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001812,intracellular cytokine staining assay measuring epitope specific interleukin-23 production by T cells,IL-23 release|ICS,An assay of epitope specific interleukin-23 production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001363,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-23 production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-23 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001812,,,,,,,,,,,,,,,,,,,,,,,,IL-23 release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-23 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001930,categorical value specification,,A value specification that is specifies one category out of a fixed number of nominal categories,false,,,http://purl.obolibrary.org/obo/OBI_0001933,,,,,,,,,,,,,,,,,,,A value specification that is specifies one category out of a fixed number of nominal categories,,,,,,,categorical value specification,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001930,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,categorical value specification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001482,intracellular cytokine staining assay measuring epitope specific transforming growth factor-beta production by T cells,TGFb release|ICS,An assay of epitope specifictransforming growth factor-beta production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001264,,,,,,,,,,,,,,,,,,,An assay of epitope specifictransforming growth factor-beta production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific transforming growth factor-beta production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001482,,,,,,,,,,,,,,,,,,,,,,,,TGFb release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific transforming growth factor-beta production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0600020,histology,histopathology,"the visual examination of cells or tissue (or images of them) with an assessment regarding a quality of the cells or tissue. Parts are: staining, imaging, judgement",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,http://purl.obolibrary.org/obo/OBI_0000441,,histopathology,,,,,,,,,,,,,"need to incorporate parts\n---\nThis is a very vague term, it should be in the same place as transcriptomics, proteomics metaboloimcs. It is the 'study' of tissues, not the process of studying tissues\n|PRS:20090901: addition of alternative term = histopathology",,"the visual examination of cells or tissue (or images of them) with an assessment regarding a quality of the cells or tissue. Parts are: staining, imaging, judgement",OBI branch derived,,,,,,histology,,the counting of the number of cells with fluorescent label at their surface to determine the percentage of the population which was activated,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000341|http://purl.obolibrary.org/obo/OBI_0302887|http://purl.obolibrary.org/obo/OBI_0600005|http://purl.obolibrary.org/obo/OBI_0000185,,,,,,,,,,,,,,,,OBI:0600020,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,histology,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Compiled by Helen Parkinson for Transcriptomics thanks to Adam Witney,,
http://purl.obolibrary.org/obo/OBI_0001309,intracellular cytokine staining assay measuring epitope specific interleukin-13 production by T cells,IL-13 release|ICS,An assay of epitope specific interleukin-13 production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001251,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-13 production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-13 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001309,,,,,,,,,,,,,,,,,,,,,,,,IL-13 release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-13 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001602,cell bound MHC direct binding assay of a MHC:ligand complex using radioactivity detection,qualitative binding|cellular MHC/direct/radioactivity,A cell bound MHC binding assay that uses radioactivity detection to detect direct binding.,false,,,http://purl.obolibrary.org/obo/OBI_0001550|http://purl.obolibrary.org/obo/OBI_0001491,,,,,,,,,,,,,,,,,,,A cell bound MHC binding assay that uses radioactivity detection to detect direct binding.,IEDB,,,,,,cell bound MHC direct binding assay of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000201,,,,,,,,,,,,,,,,OBI:0001602,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|cellular MHC/direct/radioactivity,,,,,,,,,,,,,,,,,,,,,,cell bound MHC direct binding assay of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001599,cell bound MHC competitive binding assay of a MHC:ligand complex using radioactivity detection,qualitative binding|cellular MHC/competitive/radioactivity,A cell bound MHC binding assay that uses radioactivity detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation.,false,,,http://purl.obolibrary.org/obo/OBI_0001550|http://purl.obolibrary.org/obo/OBI_0001491,,,,,,,,,,,,,,,,,,,A cell bound MHC binding assay that uses radioactivity detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation.,IEDB,,,,,,cell bound MHC competitive binding assay of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000201,,,,,,,,,,,,,,,,OBI:0001599,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|cellular MHC/competitive/radioactivity,,,,,,,,,,,,,,,,,,,,,,cell bound MHC competitive binding assay of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://usefulinc.com/ns/doap#Project,Project,,,false,,,http://www.w3.org/2002/07/owl#Thing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,doap:Project,,,,,,,,,,,,,,,,,,,http://usefulinc.com/ns/doap,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001419,ChIP-chip by tiling array assay,,An assay where chromatin immunoprecipitation (ChIP) is used in combination with tiling  microarray technology,false,,,http://purl.obolibrary.org/obo/OBI_0001248,,,,,,,,,,,,,,,,,,,An assay where chromatin immunoprecipitation (ChIP) is used in combination with tiling  microarray technology,EFO_0002762 ChIP-chip by tiling array,,,,,,ChIP-chip by tiling array assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001307,,,,,,,,,,,,,,,OBI:0001419,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ChIP-chip by tiling array assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Group: ArrayExpress production team,,
http://purl.obolibrary.org/obo/OBI_0000997,growth environment,,"The collection of material entities and their qualities that are located near a live organism, tissue or cell and can influence its growth.",false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,"The collection of material entities and their qualities that are located near a live organism, tissue or cell and can influence its growth.",OBI group,,,,,"Right now this may be incomplete. Should also cover e.g. sound, light as well.",growth environment,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000997,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,growth environment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Richard Scheuermann, Jie Zheng, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000600,JEOL NMR instrument,,An NMR instrument that is manufactured by JEOL.,false,,,http://purl.obolibrary.org/obo/OBI_0000566,,,,,,,,,,,,,,,,,NMR instrument,,An NMR instrument that is manufactured by JEOL.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400226,,,,,,JEOL NMR instrument,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000600,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,JEOL NMR instrument,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/IAO_0000594,software application,,A software application is software that can be directly executed by some processing unit.,false,,,http://purl.obolibrary.org/obo/IAO_0000010,,,,,,,,,,,,,,,,,,,A software application is software that can be directly executed by some processing unit.,http://code.google.com/p/information-artifact-ontology/issues/detail?id=80,,,,,,software application,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000594,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,software application,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot|PERSON: Michel Dumontier,,
http://purl.obolibrary.org/obo/OBI_0000473,Bruker NMR Case sample changer,,"The NMR Case is an economical NMR sample changer for laboratories with modest automation needs. It expands the maximum number of samples your spectrometer can process during unattended operation to 24. The NMR Case consists of multiple components. The NMR Case exchange module installed atop your cryostat. The two front legs are adjustable, making the NMR Case compatible with many different cryostats.",false,,,http://purl.obolibrary.org/obo/OBI_0000464,,,,,,,,,,,,,,,,,NMR instrument,,"The NMR Case is an economical NMR sample changer for laboratories with modest automation needs. It expands the maximum number of samples your spectrometer can process during unattended operation to 24. The NMR Case consists of multiple components. The NMR Case exchange module installed atop your cryostat. The two front legs are adjustable, making the NMR Case compatible with many different cryostats.",WEB:<http://www.bruker-biospin.com/automation.html>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400203,,,,,,Bruker NMR Case sample changer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000473,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker NMR Case sample changer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/IAO_0000006,narrative object,,A narrative object is an information content entity that is a set of propositions.,false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,,,,,,,,,,,,,,,,A narrative object is an information content entity that is a set of propositions.,OBI_0000013|group:OBI,,,,,"2009-08-10 Alan Ruttenberg: Larry Hunter suggests that this be obsoleted and replaced by 'textual entity' and 'figure'. Alan restored as there are OBI dependencies and this merits further discussion|agree - DENRIE. Issue(alan) do we only mean text? What about a story told by mime. Does music count? (no) what about an oral report. Regarding definition, saying it is a set of propositions means we loose the idea that wording matters. Maybe adjust saying a narrative object has some relationshop to a set of propositions",narrative object,,"Examples of narrative objects are reports, journal  articles, and patents submission.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000006,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,narrative object,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0200030,median centering,median centring,"A median centering is a data transformation that takes as input an n-dimensional (real) vector, performs a median calculation on its components, and subtracts the resulting median from each component of the input.",false,,,http://purl.obolibrary.org/obo/OBI_0200169,,http://purl.obolibrary.org/obo/OBI_0200167,,median centring,,,,,,,,,,,,,,,"A median centering is a data transformation that takes as input an n-dimensional (real) vector, performs a median calculation on its components, and subtracts the resulting median from each component of the input.",PERSON: Elisabetta Manduchi,,,,,,median centering,,"This can be used as a normalization method in expression microarray assays. For example, given a two-channel microarray assay, the log ratios of the two channels (M values) can be median-centered.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200030,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,median centering,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001402,promoter activity detection by reporter gene assay measuring epitope specific interleukin-2 production by T cells,IL-2 release|reporter gene assay,An assay of epitope specific interleukin-2 production by T cells that uses a promoter activity detection by reporter gene assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001445,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-2 production by T cells that uses a promoter activity detection by reporter gene assay.,IEDB,,,,,,promoter activity detection by reporter gene assay measuring epitope specific interleukin-2 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001402,,,,,,,,,,,,,,,,,,,,,,,,IL-2 release|reporter gene assay,,,,,,,,,,,,,,,,,,,,,,promoter activity detection by reporter gene assay measuring epitope specific interleukin-2 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001204,SNP microarray,,a DNA microarray used to detect polymorphisms in DNA samples,false,,,http://purl.obolibrary.org/obo/OBI_0400148,,,,,,,,,,,,,,,,,,,a DNA microarray used to detect polymorphisms in DNA samples,EFO_0002703 SNP array,,,,,,SNP microarray,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001204,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,SNP microarray,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0400015,BioSorter2000,,"A BioSorter2000 is a sorter manufactured by Union Biometrica. It includes analog electronics, 488/514 nm multi-line Argon-ion laser for fluorescence and a light stabilized 670 nm forward scatter laser for extinction and time-of-flight. It has filters and PMTs for 3 fluorescent parameters and photodiodes for scatter, time of flight, and extinction. The flow cell is quartz cuvette. The BioSorterTM 2000 is an instrument for analyzing and sorting objects from 500 microns to 1.5 millimeters in diameter.",false,,,http://purl.obolibrary.org/obo/OBI_0400099,,,,,,,,,,,,,,,,,,,"A BioSorter2000 is a sorter manufactured by Union Biometrica. It includes analog electronics, 488/514 nm multi-line Argon-ion laser for fluorescence and a light stabilized 670 nm forward scatter laser for extinction and time-of-flight. It has filters and PMTs for 3 fluorescent parameters and photodiodes for scatter, time of flight, and extinction. The flow cell is quartz cuvette. The BioSorterTM 2000 is an instrument for analyzing and sorting objects from 500 microns to 1.5 millimeters in diameter.",http://www.unionbio.com/products/BioSorter.html,,,,,,BioSorter2000,,BioSorter 2000 at TSRI Flow Cytometry Core Facility,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400015,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BioSorter2000,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0000680,whole organism preparation,,"A material entity which is the output of a process in which one or more whole organisms are prepared in a way to make it easier to study them, and in which the great majority of organismal parts are maintained",false,,,http://purl.obolibrary.org/obo/OBI_0100051|http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,"A material entity which is the output of a process in which one or more whole organisms are prepared in a way to make it easier to study them, and in which the great majority of organismal parts are maintained",,,http://purl.obolibrary.org/obo/OBI_0100026,,,"does this include injecting a dye to a patient to be able to visualize parts of his brain? If not, we should state that the components of the organism are substantially re-arranged.",whole organism preparation,,putting a mouse in the blender. Not: putting a mouse on a scale,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000680,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000659,,,whole organism preparation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000493,rapid resolution column,,"A rapid resolution column is a chromatography column as marketed by Agilent, which is used with a rapid resolution cartridge to ensure a fast chromatography process with good separation resolution.",false,,,http://purl.obolibrary.org/obo/OBI_0000932,,,,,,,,,,,,,,,,,,,"A rapid resolution column is a chromatography column as marketed by Agilent, which is used with a rapid resolution cartridge to ensure a fast chromatography process with good separation resolution.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01102,,,,,,rapid resolution column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000372,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000493,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,rapid resolution column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001324,in vivo assay measuring T cell epitope specific tolerance induction,tolerance|in vivo assay,An efficacy of T cell epitope intervention experiment that uses a tolerance induction intervention experiment.,false,,,http://purl.obolibrary.org/obo/OBI_0001484,,,,,,,,,,,,,,,,,,,An efficacy of T cell epitope intervention experiment that uses a tolerance induction intervention experiment.,IEDB,,,,,,in vivo assay measuring T cell epitope specific tolerance induction,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001324,,,,,,,,,,,,,,,,,,,,,,,,tolerance|in vivo assay,,,,,,,,,,,,,,,,,,,,,,in vivo assay measuring T cell epitope specific tolerance induction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001799,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-9 production by T cells,IL-9 release|RNA/DNA detection,An assay of epitope specific interleukin-9 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001253,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-9 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-9 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001799,,,,,,,,,,,,,,,,,,,,,,,,IL-9 release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-9 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001551,access service,,"A service in which a service consumer receives the right to use a resource (instrument, database, software, etc) that is owned or managed by a service provider.  Ownership of the accessed resource remains with the service provider during and after provision of service.",false,,,http://purl.obolibrary.org/obo/OBI_0001173,,,,,,,,,,,,,,,,,,,"A service in which a service consumer receives the right to use a resource (instrument, database, software, etc) that is owned or managed by a service provider.  Ownership of the accessed resource remains with the service provider during and after provision of service.",PERSON:  Matthew Brush,,,,,Need to come up wiht a proper logical defintion. One option woudl be to dfine provides_access_to property as shortcut of participants in a process.,access service,,A service that provides acess to a mass spectrometer.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001551,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,access service,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Carlo Torniai|PERSON: Matthew Brush,,
http://purl.obolibrary.org/obo/GO_0097280,histamine secretion mediated by immunoglobulin,,Histamine release triggered by the binding of an antigen to an immunoglobulin bound to the cell surface.,false,,,http://purl.obolibrary.org/obo/GO_0006955,,,,,,,,,,,,,,,,,,,Histamine release triggered by the binding of an antigen to an immunoglobulin bound to the cell surface.,,,,,,,histamine secretion mediated by immunoglobulin,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0097280,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,histamine secretion mediated by immunoglobulin,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0097281,immune complex formation,,"The process that gives rise to an immune complex. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution. Examples are the clumping of cells such as bacteria or red blood cells in the presence of an antibody, precipitation of a toxin after an antibody binds to it, and clumping of viral particles as a result of antibody binding to the virus.",false,,,http://purl.obolibrary.org/obo/GO_0016064,,,,,,,,,,,,,,,,,,,"The process that gives rise to an immune complex. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution. Examples are the clumping of cells such as bacteria or red blood cells in the presence of an antibody, precipitation of a toxin after an antibody binds to it, and clumping of viral particles as a result of antibody binding to the virus.",,,,,,,immune complex formation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0097281,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,immune complex formation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0097282,immunoglobulin-mediated neutralization,,The inhibition of an antigen's biological effects by antibody binding to it. An example is neutralization of diphtheria toxin by preventing its entry into human cells via the binding of antibody specific for diphtheria toxin.,false,,,http://purl.obolibrary.org/obo/GO_0016064,,,,,,,,,,,,,,,,,,,The inhibition of an antigen's biological effects by antibody binding to it. An example is neutralization of diphtheria toxin by preventing its entry into human cells via the binding of antibody specific for diphtheria toxin.,,,,,,,immunoglobulin-mediated neutralization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0097282,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,immunoglobulin-mediated neutralization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0002011,Human 2.1M Whole-Genome CGH Tiling Array v2.0,Nimblegen Human 2.1M Whole-Genome CGH Tiling Array v2.0,A tiling array which is manufactured by the Nimblegen corporation. Built to analyze DNA sequence copy number by comparative genomic hybridization for human DNA against 2.1 million features.,false,,,http://purl.obolibrary.org/obo/OBI_0001307,,,,Nimblegen Human 2.1M Whole-Genome CGH Tiling Array v2.0,,,,,,,,,,,,,,,A tiling array which is manufactured by the Nimblegen corporation. Built to analyze DNA sequence copy number by comparative genomic hybridization for human DNA against 2.1 million features.,http://www.nimblegen.com/downloads/support/05434483001_NG_CGHLOH_UGuide_v9p1.pdf,,,,,,Human 2.1M Whole-Genome CGH Tiling Array v2.0,,"Filges, Isabel, et al. ""Reduced expression by SETBP1 haploinsufficiency causes developmental and expressive language delay indicating a phenotype distinct from Schinzel–Giedion syndrome."" Journal of medical genetics 48.2 (2011): 117-122. PMID:21037274",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002011,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Human 2.1M Whole-Genome CGH Tiling Array v2.0,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"PERSON: Venkat Malladi, Chris Stoeckert, Jie Zheng, Alan Ruttenberg",,
http://purl.obolibrary.org/obo/OBI_1110086,restricting MHC role,,The role played by an MHC molecule by binding a material entity playing the role of epitope when that epitope/MHC molecule pair are recognized (bound) by a TCR molecule on the surface of a cell playing the role of effector cell.,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,,,The role played by an MHC molecule by binding a material entity playing the role of epitope when that epitope/MHC molecule pair are recognized (bound) by a TCR molecule on the surface of a cell playing the role of effector cell.,IEDB,,,,,,restricting MHC role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110086,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,restricting MHC role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001012,RNASE V1 structure mapping assay,single nucleotide resolution mapping assay using RNAse V1,a single-nucleotide-resolution ribonucleic acid structure mapping assay which uses RNAse V1 as reagent and enzymatic probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,false,,,http://purl.obolibrary.org/obo/OBI_0001014,,http://purl.obolibrary.org/obo/OBI_0000441,,single nucleotide resolution mapping assay using RNAse V1,,,,,,,,,,,,,,,a single-nucleotide-resolution ribonucleic acid structure mapping assay which uses RNAse V1 as reagent and enzymatic probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,RNA ontology,,,,,,RNASE V1 structure mapping assay,,PMID:7031604,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_33697,,,,OBI:0001012,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,RNASE V1 structure mapping assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001326,cytometric bead array assay measuring epitope specific interleukin-4 production by T cells,IL-4 release|cytometric bead array,An assay of epitope specific interleukin-4 production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001450,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-4 production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific interleukin-4 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001326,,,,,,,,,,,,,,,,,,,,,,,,IL-4 release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific interleukin-4 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/PATO_0000122,length,,A 1-D extent quality which is equal to the distance between two points.,false,,,http://purl.obolibrary.org/obo/BFO_0000019,,,,,,,,,,,,,,,,,,,A 1-D extent quality which is equal to the distance between two points.,,,,,,,length,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,length,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0000125,mass,,A physical quality that inheres in a bearer by virtue of the proportion of the bearer's amount of matter.,false,,,http://purl.obolibrary.org/obo/BFO_0000019,,,,,,,,,,,,,,,,,,,A physical quality that inheres in a bearer by virtue of the proportion of the bearer's amount of matter.,,,,,,,mass,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,mass,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001510,mass spectrometry assay measuring MHC ligand processing and presentation of MHC ligands eluted from secreted MHC,ligand presentation|secreted MHC/mass spectrometry ,A mass spectrometry of MHC ligands that identifies eluted ligands from secreted MHC.,false,,,http://purl.obolibrary.org/obo/OBI_0001478,,,,,,,,,,,,,,,,,,,A mass spectrometry of MHC ligands that identifies eluted ligands from secreted MHC.,IEDB,,,,,,mass spectrometry assay measuring MHC ligand processing and presentation of MHC ligands eluted from secreted MHC,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000470,,,,,,,,,,,,,,,,OBI:0001510,,,,,,,,,,,,,,,,,,,,,,,,ligand presentation|secreted MHC/mass spectrometry ,,,,,,,,,,,,,,,,,,,,,,mass spectrometry assay measuring MHC ligand processing and presentation of MHC ligands eluted from secreted MHC,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/CHEBI_33697,ribonucleic acid,,"High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins.",false,,,http://purl.obolibrary.org/obo/CHEBI_33696,,,,,,,,,,,,,,,,,,,"High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins.",,,,,,,ribonucleic acid,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:33697,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,ribonucleic acid,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_1110152,ELISA measuring epitope specific interleukin-2 production by T cells,IL-2 release|ELISA,An assay of epitope specific interleukin-2 production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001445,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-2 production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific interleukin-2 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110152,,,,,,,,,,,,,,,,,,,,,,,,IL-2 release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific interleukin-2 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001781,cytometric bead array assay measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells,CCL9/MIP-1g release|cytometric bead array,An assay of epitope specific macrophage inflammatory protein-1 gamma production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001456,,,,,,,,,,,,,,,,,,,An assay of epitope specific macrophage inflammatory protein-1 gamma production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001781,,,,,,,,,,,,,,,,,,,,,,,,CCL9/MIP-1g release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001951,reverse PCR primer,3' primer|reverse primer|antisense primer,"A short oligonucleotide complementary to target DNA (5'->3' on minus strand) that acts as the leader for DNA extension in a PCR reaction. The polymerase starts replication at the 3'-end of the primer, and copies the opposite strand. A primer is characterized by its 'melting temperature' (Tm) and pairs of primers should have similar Tm.",false,,,http://purl.obolibrary.org/obo/CHEBI_16991|http://purl.obolibrary.org/obo/OBI_0001879,,,,3' primer|reverse primer|antisense primer,,,,,,,,,,,,,,,"A short oligonucleotide complementary to target DNA (5'->3' on minus strand) that acts as the leader for DNA extension in a PCR reaction. The polymerase starts replication at the 3'-end of the primer, and copies the opposite strand. A primer is characterized by its 'melting temperature' (Tm) and pairs of primers should have similar Tm.","adapted from ""http://www.ncbi.nlm.nih.gov/projects/genome/probe/doc/Glossary.shtml#p""",,,,,,reverse PCR primer,,"5' end of luciferase, reverse primer (LucNrev	 CCTTATGCAGTTGCTCTCC)|",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001951,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,reverse PCR primer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001987,assay measuring the association constant [KA] of a MHC:ligand complex,association constant KA|binding assay|1/M,A MHC binding constant determination assay measuring equilibrium association constant (KA).,false,,,http://purl.obolibrary.org/obo/OBI_0001553,,,,,,,,,,,,,,,,,,,A MHC binding constant determination assay measuring equilibrium association constant (KA).,IEDB,,,,,,assay measuring the association constant [KA] of a MHC:ligand complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001987,,,,,,,,,,,,,,,,,,,,,,,,association constant KA|binding assay|1/M,,,,,,,,,,,,,,,,,,,,,,assay measuring the association constant [KA] of a MHC:ligand complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0002036,array based nucleic acid structure mapping assay,,An assay which aims to provide information about the in vivo organization/structure of nucleic acids using chemical or enzymatic probes using a microarray.,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,An assay which aims to provide information about the in vivo organization/structure of nucleic acids using chemical or enzymatic probes using a microarray.,OBI:0000870,,,,,Details see tracker: https://sourceforge.net/p/obi/obi-terms/725/,array based nucleic acid structure mapping assay,,pmid:23580730,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002036,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,array based nucleic acid structure mapping assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Saccharomyces Genome Database (SGD),,,,,,,,"Janos Demeter, Chris Stoeckert",,
http://purl.obolibrary.org/obo/OBI_0200053,expectation maximization,,EM is a probabilistic algorithm used to estimate the maximum likelihood of parameters from existing data where the model involves unobserved latent variables. The input to this method is the data model for which the estimation is performed over and the output is an approximated probability function.,false,,,http://purl.obolibrary.org/obo/OBI_0200052,,,,,,,,,,,,,,,,,,,EM is a probabilistic algorithm used to estimate the maximum likelihood of parameters from existing data where the model involves unobserved latent variables. The input to this method is the data model for which the estimation is performed over and the output is an approximated probability function.,PERSON: James Malone,,,,,,expectation maximization,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200053,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,expectation maximization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0001574,obsolete cell lysate MHC competitive binding assay using radioactivity detection,cell lysate MHC competitive binding using radioactivity,competitive inhibition of binding assay measuring MHC ligand binding by radioactivity detection using MHC derived from a cell lysate,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,competitive inhibition of binding assay measuring MHC ligand binding by radioactivity detection using MHC derived from a cell lysate,IEDB (QTT),,,,,,obsolete cell lysate MHC competitive binding assay using radioactivity detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000227,,,,,,,,,,,,,,,,,,OBI:0001574,,,,,,,,,,,,,,,,,,,,,,,,cell lysate MHC competitive binding using radioactivity,,,,,,,,,,,,,,,,,,,,,,obsolete cell lysate MHC competitive binding assay using radioactivity detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",http://purl.obolibrary.org/obo/OBI_0001544,
http://purl.obolibrary.org/obo/NCBITaxon_32524,Amniota,amniotes,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_32523,,,,amniotes,,,,,,,,,,,,,,,,,,,,,,Amniota,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:32524,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Amniota,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/CL_0000001,primary cultured cell,,"A cultured cell that is freshly isolated from a organismal source, or derives in culture from such a cell prior to the culture being passaged.",false,,,http://purl.obolibrary.org/obo/CL_0000010,,,,,,,,,,,,,,,,,,,"A cultured cell that is freshly isolated from a organismal source, or derives in culture from such a cell prior to the culture being passaged.",,,,,,,primary cultured cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CL:0000001,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/cl.owl,,,,,,,,,,,,,,,,,,,primary cultured cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/CL_0000000,cell,,A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.,false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.,,,,,,,cell,,"PMID:18089833.Cancer Res. 2007 Dec 15;67(24):12018-25. ""...Epithelial cells were harvested from histologically confirmed adenocarcinomas ..""",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CL:0000000,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/cl.owl,,,,,,,,,,,,,,,,,,,cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/CL_0000003,native cell,,"A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment).",false,,,http://purl.obolibrary.org/obo/CL_0000000,,,,,,,,,,,,,,,,,,,"A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment).",,,,,,,native cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CL:0000003,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/cl.owl,,,,,,,,,,,,,,,,,,,native cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001014,single-nucleotide-resolution nucleic acid structure mapping assay using enzymatic probing,,a single-nucleotide-resolution nucleic acid structure mapping assay which relies on proteins acting as enzymatic probes  in order to produce measurement information which one interpreted provide structural information about the RNA species under study.,false,,,http://purl.obolibrary.org/obo/OBI_0000870,,,,,,,,,,,,,,,,,,,a single-nucleotide-resolution nucleic acid structure mapping assay which relies on proteins acting as enzymatic probes  in order to produce measurement information which one interpreted provide structural information about the RNA species under study.,RNAO and OBI,,,,,,single-nucleotide-resolution nucleic acid structure mapping assay using enzymatic probing,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001014,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,single-nucleotide-resolution nucleic acid structure mapping assay using enzymatic probing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/CLO_0000019,immortal cell line cell,,"A cell line cell that is expected to be capable of an unlimited number of divisions, and is thus able to support indefinite propagation in vitro as part of an immortal cell line.",false,,,http://purl.obolibrary.org/obo/CLO_0000001,,,,,,,,,,,,,,,,,,,"A cell line cell that is expected to be capable of an unlimited number of divisions, and is thus able to support indefinite propagation in vitro as part of an immortal cell line.",,,,,,,immortal cell line cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CLO:0000019,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/clo.owl,,,,,,,,,,,,,,,,,,,immortal cell line cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000169,placebo role,placebo,a negative reference substance is a reference role in which the substance playing the reference substance role is physically similar in appearance to the test substance,false,,,http://purl.obolibrary.org/obo/OBI_0000214,,,,placebo,,,,,,,,,,,,,"CDISC definition placebo. A pharmaceutical preparation that does not contain the investigational agent. In blinded studies, it is generally prepared to be physically indistinguishable from the preparation containing the investigational product.",,a negative reference substance is a reference role in which the substance playing the reference substance role is physically similar in appearance to the test substance,,,,,,,placebo role,,Pill consisting of inert materials,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000169,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,placebo role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0001800,ELISPOT assay measuring epitope specific interleukin-8 production by T cells,IL-8 release|ELISPOT,An assay of epitope specific interleukin-8 production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001218,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-8 production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific interleukin-8 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001800,,,,,,,,,,,,,,,,,,,,,,,,IL-8 release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific interleukin-8 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0400063,LactoScope C4,,"A LactoScope_C4 is a spectrophotometer with which the composition of milk and milk products is analysed via infrared technology. The LactoScope determines the amount of the constituents fat, protein, lactose and the total solids content with extreme accuracy.",false,,,http://purl.obolibrary.org/obo/OBI_0400115,,,,,,,,,,,,,,,,,,,"A LactoScope_C4 is a spectrophotometer with which the composition of milk and milk products is analysed via infrared technology. The LactoScope determines the amount of the constituents fat, protein, lactose and the total solids content with extreme accuracy.",http://www.aicompanies.com/DeltaCD/lacto_ftir_auto.htm,,,,,,LactoScope C4,,LactoScope C4 Automatic Economical,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400063,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,LactoScope C4,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Josef Spidlen|Melanie Courtot,,
http://purl.obolibrary.org/obo/CL_0000842,mononuclear cell,,A leukocyte with a single non-segmented nucleus in the mature form.,false,,,http://purl.obolibrary.org/obo/CL_0000000,,,,,,,,,,,,,,,,,,,A leukocyte with a single non-segmented nucleus in the mature form.,,,,,,,mononuclear cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CL:0000842,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/cl.owl,,,,,,,,,,,,,,,,,,,mononuclear cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000495,vacuum degasser,,"A degassing system used for degassing solvents in liquid chromatography. Dissolved gasses, usually nitrogen and oxygen from the air, tend to be evolved in the mobile phase as the pressure is reduced when the mobile phase leaves the liquid chromatography column and enters the detector. Gasses in the mobile phase in the detector can produce completely unacceptable noise and, thus, must be removed. The dissolved gasses were originally removed under vacuum but, unfortunately, are soon replaced if the solvent is left in contact with air at atmospheric pressure. For this reason degassing is now usually carried out by bubbling helium through the mobile phase reservoirs. Secondly, vacuum is used in the thermionic detector. This consists of a device, very similar in design to the thermionic valve which is attached to a vacuum and a small quantity of the eluent from a gas chromatography column allowed to bleed through it. Helium is used as the carrier gas. The presence of solute vapor causes the thermionic current to fall. This type of detector tends to become contaminated rather readily.",false,,,http://purl.obolibrary.org/obo/OBI_0000589,,,,,,,,,,,,,,,,,,,"A degassing system used for degassing solvents in liquid chromatography. Dissolved gasses, usually nitrogen and oxygen from the air, tend to be evolved in the mobile phase as the pressure is reduced when the mobile phase leaves the liquid chromatography column and enters the detector. Gasses in the mobile phase in the detector can produce completely unacceptable noise and, thus, must be removed. The dissolved gasses were originally removed under vacuum but, unfortunately, are soon replaced if the solvent is left in contact with air at atmospheric pressure. For this reason degassing is now usually carried out by bubbling helium through the mobile phase reservoirs. Secondly, vacuum is used in the thermionic detector. This consists of a device, very similar in design to the thermionic valve which is attached to a vacuum and a small quantity of the eluent from a gas chromatography column allowed to bleed through it. Helium is used as the carrier gas. The presence of solute vapor causes the thermionic current to fall. This type of detector tends to become contaminated rather readily.",WEB:<http://www.chromatography-online.org/topics/vacuum.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01053,,,,,,vacuum degasser,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000495,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,vacuum degasser,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001917,chromosome conformation identification objective,,A molecular feature identification objective that aims to determine spatial organization of chromatin.,false,,,http://purl.obolibrary.org/obo/OBI_0000131,,,,,,,,,,,,,,,,,,,A molecular feature identification objective that aims to determine spatial organization of chromatin.,Group: Penn Group,,,,,,chromosome conformation identification objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001917,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,chromosome conformation identification objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/CHEBI_37987,Cy3 dye,,,false,,,http://purl.obolibrary.org/obo/REO_0000280,,,,,,,,,,,,,,,,,,,,,,,,,,Cy3 dye,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/REO_0000171,,,,,,,,,,,,CHEBI:37987,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,Cy3 dye,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200104,principal component regression,,"The Principal Component Regression method is a regression analysis method that combines the Principal Component Analysis (PCA)spectral decomposition with an Inverse Least Squares (ILS) regression method to create a quantitative model for complex samples. Unlike quantitation methods based directly on Beer's Law which attempt to calculate the absorbtivity coefficients for the constituents of interest from a direct regression of the constituent concentrations onto the spectroscopic responses, the PCR method regresses the concentrations on the PCA scores.",false,,,http://purl.obolibrary.org/obo/OBI_0200175|http://purl.obolibrary.org/obo/OBI_0200102,,,,,,,,,,,,,,,,,,,"The Principal Component Regression method is a regression analysis method that combines the Principal Component Analysis (PCA)spectral decomposition with an Inverse Least Squares (ILS) regression method to create a quantitative model for complex samples. Unlike quantitation methods based directly on Beer's Law which attempt to calculate the absorbtivity coefficients for the constituents of interest from a direct regression of the constituent concentrations onto the spectroscopic responses, the PCR method regresses the concentrations on the PCA scores.","WEB: : http://www.thermo.com/com/cda/resources/resources_detail/1,2166,13414,00.html",,,,,,principal component regression,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200104,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,principal component regression,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Tina Hernandez-Boussard,,
http://purl.obolibrary.org/obo/OBI_0001611,obsolete purified MHC direct binding assay,purified MHC direct binding ,direct binding assay measuring MHC ligand binding using MHC derived from a purified MHC molecule preparation,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,direct binding assay measuring MHC ligand binding using MHC derived from a purified MHC molecule preparation,IEDB (QTT),,,,,,obsolete purified MHC direct binding assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,OBI:0001611,,,,,,,,,,,,,,,,,,,,,,,,purified MHC direct binding ,,,,,,,,,,,,,,,,,,,,,,obsolete purified MHC direct binding assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001641,biological activity assay measuring epitope specific complement-dependent cytotoxicity,complement-dependent cytotoxicity|biological activity,A B cell epitope specific activation of additional immune response in vitro assay that detects complement-dependent cytotoxicity.,false,,,http://purl.obolibrary.org/obo/OBI_0001704,,,,,,,,,,,,,,,,,,,A B cell epitope specific activation of additional immune response in vitro assay that detects complement-dependent cytotoxicity.,IEDB,,,,,,biological activity assay measuring epitope specific complement-dependent cytotoxicity,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001641,,,,,,,,,,,,,,,,,,,,,,,,complement-dependent cytotoxicity|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific complement-dependent cytotoxicity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001016,DNASE 1 structure mapping assay,DNAse footprinting assay|single nucleotide resolution mapping assay using DNAse I,a single-nucleotide-resolution deoxyribonucleic acid structure mapping assay which uses DNAse 1 as reagent and enzymatic probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,false,,,http://purl.obolibrary.org/obo/OBI_0001014,,http://purl.obolibrary.org/obo/OBI_0000441,,DNAse footprinting assay|single nucleotide resolution mapping assay using DNAse I,,,,,,,,,,,,,,,a single-nucleotide-resolution deoxyribonucleic acid structure mapping assay which uses DNAse 1 as reagent and enzymatic probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,RNA ontology,,,,,,DNASE 1 structure mapping assay,,PMID:3773731,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_16991,,,,OBI:0001016,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNASE 1 structure mapping assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001133,denaturing high-performance liquid chromatography instrument,,A high performance liquid chromatography instrument that employs temperature-dependent separation of DNA containing mismatched base pairs from PCR-amplified DNA fragments for chromatographic mutation analysis.,false,,,http://purl.obolibrary.org/obo/OBI_0000932,,,,,,,,,,,,,,,,,,,A high performance liquid chromatography instrument that employs temperature-dependent separation of DNA containing mismatched base pairs from PCR-amplified DNA fragments for chromatographic mutation analysis.,doi:10.1385/1-59259-850-1:173,,,,,,denaturing high-performance liquid chromatography instrument,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000372,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001133,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,denaturing high-performance liquid chromatography instrument,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0000699,survival assessment,"",Survival assessment is an assay that measures the occurrence of death events in one or more organisms that are monitored over time,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,http://purl.obolibrary.org/obo/OBI_0000441,,,,,,,,,,,,,,,,,Survival assessment is an assay that measures the occurrence of death events in one or more organisms that are monitored over time,,,,,,Need to point out more specifically that survival / death is measured.,survival assessment,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100026,,,,OBI:0000699,,,,,,,,,,,,,,,,,,,,,,,,"",,,,,,,,,,,,,,,,,,,,,,survival assessment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001577,cytometric bead array assay measuring epitope specific intracellular cytokine staining (ICS) IL-22 production by T cells,IL-22 release|cytometric bead array,An assay of epitope specific interleukin-22 production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001217,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-22 production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific intracellular cytokine staining (ICS) IL-22 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001577,,,,,,,,,,,,,,,,,,,,,,,,IL-22 release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific intracellular cytokine staining (ICS) IL-22 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0600011,acclimatization,,"A protocol application in which an object is left in an environment for some period of time, until some qualities of interest are in equilibrium with that environment.",false,,,http://purl.obolibrary.org/obo/OBI_0600009,,,,,,,,,,,,,,,,,,,"A protocol application in which an object is left in an environment for some period of time, until some qualities of interest are in equilibrium with that environment.","CEBS, Biomaterial_branch",,,,,,acclimatization,,"placing mice in animal facility for 2 weeks prior to an experiment to accustom them to their environment, reducing stress",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600011,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,acclimatization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel,,
http://purl.obolibrary.org/obo/IAO_0000312,publication about an investigation,scientific publication,A publication that is about an investigation,false,,,http://purl.obolibrary.org/obo/IAO_0000311,,,,scientific publication,,,,,,,,,,,,,,,A publication that is about an investigation,,,,,,,publication about an investigation,,Most scientific journal articles,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000312,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000066,,,,,,,,,,,,,,,,publication about an investigation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/IAO_0000401,one dimensional cartesian spatial coordinate datum,,A cartesion spatial coordinate datum that  uses one value to specify a position along a one dimensional spatial region,false,,,http://purl.obolibrary.org/obo/IAO_0000400,,,,,,,,,,,,,,,,,,,A cartesion spatial coordinate datum that  uses one value to specify a position along a one dimensional spatial region,,,,,,,one dimensional cartesian spatial coordinate datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000401,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,one dimensional cartesian spatial coordinate datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0000681,separation into different composition objective,,"A material separation objective aiming to separate a material entity that has parts of different types, and end with at least one output that is a material with parts of fewer types (modulo impurities).",false,,,http://purl.obolibrary.org/obo/OBI_0000639,,,,,,,,,,,,,,,,,,,"A material separation objective aiming to separate a material entity that has parts of different types, and end with at least one output that is a material with parts of fewer types (modulo impurities).",,,,,,We should be using has the grain relations or concentrations to distinguish the portioning and other sub-objectives,separation into different composition objective,,The objective to obtain cells contained in a sample of blood.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000681,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,separation into different composition objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200106,discriminant analysis,,Discriminant function analysis is used to determine which variables discriminate between two or more naturally occurring groups. Analysis is used to determine which variable(s) are the best predictors of a particular outcome.,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,Discriminant function analysis is used to determine which variables discriminate between two or more naturally occurring groups. Analysis is used to determine which variable(s) are the best predictors of a particular outcome.,WEB: http://www.statsoft.com/textbook/stdiscan.html,,,,,,discriminant analysis,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200106,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,discriminant analysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Tina Hernandez-Boussard,,
http://purl.obolibrary.org/obo/OBI_0001152,transfection,,"a genetic transformation which relies on the use of physical, electrical and chemical phenomena to introduce DNA or RNA into a cell",false,,,http://purl.obolibrary.org/obo/OBI_0600043,,,,,,,,,,,,,,,,,,,"a genetic transformation which relies on the use of physical, electrical and chemical phenomena to introduce DNA or RNA into a cell",MO_366 transfection,,,,,,transfection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0600033,,,,,,,,,,,,,,,,OBI:0001152,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,transfection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0400105,arrayer,,a device which deposits biological material onto a substrate in a defined pattern.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,a device which deposits biological material onto a substrate in a defined pattern.,MO_697 arrayer,,,,,,arrayer,,"BioRobotics Microgrid II TAS, Affymetrix GMS 417",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000383,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400105,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,arrayer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Trish Whetzel,,
http://purl.obolibrary.org/obo/OBI_0000828,research organization,,An organization formed with a goal to have its members conduct investigations,false,,,http://purl.obolibrary.org/obo/OBI_0000245,,,,,,,,,,,,,,,,,,,An organization formed with a goal to have its members conduct investigations,,,,,,,research organization,,The SALK institute is a research organization. ,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000828,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,research organization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0500002,repeated measure design,,a study design which use the same individuals and exposure them to a set of conditions. The effect of order and practice can be confounding factor in such designs,false,,,http://purl.obolibrary.org/obo/OBI_0000115,,,,,,,,,,,,,,,,,,,a study design which use the same individuals and exposure them to a set of conditions. The effect of order and practice can be confounding factor in such designs,http://www.holah.karoo.net/experimentaldesigns.htm,,,,,,repeated measure design,,"PMID: 10959922.J Biopharm Stat. 2000 Aug;10(3):433-45.Equivalence in test assay method comparisons for the repeated-measure, matched-pair design in medical device studies: statistical considerations.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500002,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,repeated measure design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0001947,sequence annotation provider,annotation provider,A person or organization reporting the feature annotation results from the analysis of a macromolecular sequence.,false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,A person or organization reporting the feature annotation results from the analysis of a macromolecular sequence.,NIAID GSCID-BRC metadata working group,,,,,,sequence annotation provider,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001947,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sequence annotation provider,,,,,,annotation provider,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Jie Zheng, Chris Stoeckert",,
http://purl.obolibrary.org/obo/OBI_0002075,MHC ligand assay,ligand presentation/binding|binding assay,An immune epitope assay that detects either the processing and presentation of a ligand by an antigen presenting cell or the binding of a ligand to an MHC molecule.,false,,,http://purl.obolibrary.org/obo/OBI_1110128|http://purl.obolibrary.org/obo/OBI_0001146,,,,,,,,,,,,,,,,,,,An immune epitope assay that detects either the processing and presentation of a ligand by an antigen presenting cell or the binding of a ligand to an MHC molecule.,IEDB,,,,,,MHC ligand assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002075,,,,,,,,,,,,,,,,,,,,,,,,ligand presentation/binding|binding assay,,,,,,,,,,,,,,,,,,,,,,MHC ligand assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001728,ELISA measuring the dissociation constant [KD] of a B cell epitope:antibody complex,dissociation constant KD|ELISA|nM,A B cell epitope equilibrium dissociation constant (KD) determination assay that uses an enzyme-linked immunosorbent assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001708,,,,,,,,,,,,,,,,,,,A B cell epitope equilibrium dissociation constant (KD) determination assay that uses an enzyme-linked immunosorbent assay.,IEDB,,,,,,ELISA measuring the dissociation constant [KD] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001728,,,,,,,,,,,,,,,,,,,,,,,,dissociation constant KD|ELISA|nM,,,,,,,,,,,,,,,,,,,,,,ELISA measuring the dissociation constant [KD] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/UBERON_0001088,urine,,Excretion that is the output of a kidney,false,,,http://purl.obolibrary.org/obo/CARO_0000004,,,,,,,,,,,,,,,,,,,Excretion that is the output of a kidney,,,,,,,urine,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UBERON:0001088,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uberon.owl,,,,,,,,,,,,,,,,,,,urine,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000026,cytological stain role,cytological stain,A dye role that is realized when the stain is used to colour cells and or cellular components for the purposes of visualization,false,,,http://purl.obolibrary.org/obo/OBI_0000250,,,,cytological stain,,,,,,,,,,,,,,,A dye role that is realized when the stain is used to colour cells and or cellular components for the purposes of visualization,,,,,,,cytological stain role,,haemotoxylin is a general purpose nuclear stain extracted from the wood of the logwood tree WEB: http://en.wikipedia.org/wiki/Haematoxylin,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000026,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cytological stain role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Jennifer Fostel|Person:Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0400033,diode laser,,"A diode laser is a laser in which the active medium is a p-n junction semiconductor laser diode, similar to that found in a light-emitting diode. Laser diodes emit at wavelengths from 375 nm to 1800 nm, and wavelengths of over 3 micrometer have been demonstrated. A diode laser can by used to irradiate cells in a flow cytometer.",false,,,http://purl.obolibrary.org/obo/OBI_0400064,,,,,,,,,,,,,,,,,,,"A diode laser is a laser in which the active medium is a p-n junction semiconductor laser diode, similar to that found in a light-emitting diode. Laser diodes emit at wavelengths from 375 nm to 1800 nm, and wavelengths of over 3 micrometer have been demonstrated. A diode laser can by used to irradiate cells in a flow cytometer.",John Quinn,,,,,,diode laser,,"FAX-RS3-H0 diode laser manufactured by Diode Laser Concepts, Inc.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400033,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,diode laser,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Daniel Schober,,
http://purl.obolibrary.org/obo/GO_0003674,molecular_function,,"Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.",false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,"Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.",,,,,,,molecular_function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0003674,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,molecular_function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000870,single-nucleotide-resolution nucleic acid structure mapping assay,,is an assay which aims to provide information about the secondary structure of nucleic acids using chemical or enzymatic probing to establish the extent of base-pairing or solvent accessiblity.,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,is an assay which aims to provide information about the secondary structure of nucleic acids using chemical or enzymatic probing to establish the extent of base-pairing or solvent accessiblity.,RNAO,,,,,2010-01-31: Philippe Rocca-Serra: OBI needs to review 'structure assay' as currently defined. Need to get feedback from Kevin Clancy.,single-nucleotide-resolution nucleic acid structure mapping assay,,"",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000870,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,single-nucleotide-resolution nucleic acid structure mapping assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0302731,buffer role,buffer,a role which inheres in some molecular entity realized during the process of buffering,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,buffer,,,,,,,,,,,,,,,a role which inheres in some molecular entity realized during the process of buffering,OBI,,,,,,buffer role,,"A buffer of carbonic acid (H2CO3) and bicarbonate (HCO3-) is present in blood plasma, to maintain a pH between 7.35 and 7.45. http://en.wikipedia.org/wiki/Buffer_solution",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302731,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,buffer role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Helen Parkinson|Person:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0400061,jet_in_air_flow_chamber,,A flow cell in which the cells are pinched off as droplets and allowed to drop through the air. The laser intersects with the cell in mid-air. A jet in air flow chamber allows the laser to intersect with the cells without any intermittent media other than air.,false,,,http://purl.obolibrary.org/obo/BFO_0000029,,,,,,,,,,,,,,,,,,,A flow cell in which the cells are pinched off as droplets and allowed to drop through the air. The laser intersects with the cell in mid-air. A jet in air flow chamber allows the laser to intersect with the cells without any intermittent media other than air.,http://www.flocyte.com/FRTP/Resources/flow_cytometry_glossary.htm,,,,,,jet_in_air_flow_chamber,,Jet-in-air flow chamber in DakoCytomation MoFlo high-speed cell sorter,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400061,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,jet_in_air_flow_chamber,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0000789,survival rate,,A measurement data that represents the percentage of people or animals in a study or treatment group who are alive for a given period of time after diagnosis or initiation of monitoring.,false,,,http://purl.obolibrary.org/obo/IAO_0000109,,,,,,,,,,,,,,,,,,,A measurement data that represents the percentage of people or animals in a study or treatment group who are alive for a given period of time after diagnosis or initiation of monitoring.,"adapted from wikipedia
http://en.wikipedia.org/wiki/Survival_rate",,,,,,survival rate,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000789,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,survival rate,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Oliver He,,
http://purl.obolibrary.org/obo/OBI_0000976,handedness categorical measurement datum,,"A datum used to record the answer to a self assessment of whether a person uses their left hand, right hand primarily or each hand equally",false,,,http://purl.obolibrary.org/obo/OBI_0000938,,,,,,,,,,,,,,,,,,,"A datum used to record the answer to a self assessment of whether a person uses their left hand, right hand primarily or each hand equally",,,,,,,handedness categorical measurement datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000976,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/PATO_0002201,,,,,,,,handedness categorical measurement datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Alan Ruttenberg|PERSON:Jessica Turner,,
http://purl.obolibrary.org/obo/OBI_0000548,isolation of PBMCs,,a process in which cells with a single nucleus are isolated from a blood sample,false,,,http://purl.obolibrary.org/obo/OBI_0000512,,http://purl.obolibrary.org/obo/OBI_0000681,,,,,,,,,,,,,,,,,a process in which cells with a single nucleus are isolated from a blood sample,wiki http://en.wikipedia.org/wiki/PBMC,,,,,,isolation of PBMCs,,"cells are extracted from whole blood using ficoll, a hydrophilic polysaccharide that separates layers of blood, with monocytes and lymphocytes forming a buffy coat under a layer of plasma. This buffy coat contains the PBMCs.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/UBERON_0000178,http://purl.obolibrary.org/obo/OBI_0100060,,,OBI:0000548,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,isolation of PBMCs,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: bjoern peters,,
http://purl.obolibrary.org/obo/OBI_0200035,boostrapping,,"Bootstrapping is a statistical method for estimating the sampling distribution of a statistic by sampling with replacement from the original data, most often with the purpose of deriving robust estimates of standard errors and confidence intervals of a population parameter like a mean, median, proportion, odds ratio, correlation coefficient or regression coefficient",false,,,http://purl.obolibrary.org/obo/OBI_0000792,,http://purl.obolibrary.org/obo/OBI_0200188,,,,,,,,,,,,,,,,,"Bootstrapping is a statistical method for estimating the sampling distribution of a statistic by sampling with replacement from the original data, most often with the purpose of deriving robust estimates of standard errors and confidence intervals of a population parameter like a mean, median, proportion, odds ratio, correlation coefficient or regression coefficient",Bootstrapping is a data transformation process which estimates the precision of sampling statistics by drawing randomly with replacement from a set of data points,,,,,,boostrapping,,"Although widely accepted that high throughput biological data are typically highly noisy, the effects that this uncertainty has upon the conclusions we draw from these data are often overlooked. However, in order to assign any degree of confidence to our conclusions, we must quantify these effects. Bootstrap resampling is one method by which this may be achieved.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200035,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,boostrapping,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0000876,cytoplasmic RNA extract,,A RNA extract that is the output of a RNA extraction process in which RNA molecules found in the cytoplasm are extracted.,false,,,http://purl.obolibrary.org/obo/OBI_0000880,,,,,,,,,,,,,,,,,,,A RNA extract that is the output of a RNA extraction process in which RNA molecules found in the cytoplasm are extracted.,UPenn Group,,,,,,cytoplasmic RNA extract,,"Cytoplasmic RNA extraction from mammalian tissues to create cDNA library (Carninci P, Nakamura M, Sato K, Hayashizaki Y, Brownstein MJ. Cytoplasmic RNA extraction from fresh and frozen mammalian tissues. Biotechniques. 2002;33:306–309.)",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000876,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000859,,,cytoplasmic RNA extract,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Chris Stoeckert|PERSON: Jie Zheng,,
http://purl.obolibrary.org/obo/OBI_0001000,questionnaire,,"A document with a set of printed or written questions with a choice of answers, devised for the purposes of a survey or statistical study.",false,,,http://purl.obolibrary.org/obo/IAO_0000310,,,,,,,,,,,,,,,,,,,"A document with a set of printed or written questions with a choice of answers, devised for the purposes of a survey or statistical study.",Merriam-Webster,,,,,"JT: It plays a role in collecting data that could be fleshed out more; but I'm thinking it is, in itself, an edited document. 
JZ: based on textual definition of edited document, it can be defined as N&S. I prefer to leave questionnaire as a document now. We can add more restrictions in the future and use that to determine it is an edited document or not. |Need to clarify if this is a document or a directive information entity (or what their connection is))",questionnaire,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001000,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,questionnaire,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Jessica Turner,,
http://purl.obolibrary.org/obo/IAO_0000304,caption,,A textual entity that describes a figure,false,,,http://purl.obolibrary.org/obo/IAO_0000300,,,,,,,,,,,,,,,,,,,A textual entity that describes a figure,,,,,,,caption,,"Figure 1: A system diagram describing the modules of the Hanalyzer.  Reading methods (green) take external sources of knowledge (blue) and extract information from them, either by parsing structured data or biomedical language processing to extract information from unstructured data.  Reading modules are responsible for tracking the provenance of all knowledge.  Reasoning methods (yellow) enrich the knowledge that results from reading by, for example, noting two genes that are annotated to the same ontology term or database entry.  All knowledge sources, read or reasoned, are assigned a reliability score, and all are combined using that score into a knowledge network (orange) that represents the integration of all sorts of relationship between a pair of genes and a combined reliability score.  A data network (also orange) is created from experimental results to be analyzed.  The reporting modules (pink) integrate the data and knowledge networks, producing visualizations that can be queried with the associated drill-down tool.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000304,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000308,,,,,,,,,,,,,,,,caption,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/NCBITaxon_2759,Eukaryota,eucaryotes|eukaryotes,,false,,,http://purl.obolibrary.org/obo/OBI_0100026,,,,eucaryotes|eukaryotes,,,,,,,,,,,,,,,,,,,,,,Eukaryota,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:2759,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Eukaryota,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000583,refractive index detector,,"For analyzing non-UV absorbing substances, such as carbohydrates, lipids and polymers. This is also the detector of choice for gel permeation chromatography. The refractive index detector is one of the least sensitive LC detectors. It is very sensitive to changes in ambient temperature, pressure changes, flow-rate changes and can not be used for gradient elution. Despite these many disadvantages, this detector is extremely useful for detecting those compounds that are nonionic, do not adsorb in the UV, and do not fluoresce. There are many optical systems used in refractive index detectors but one of the most common is the differential refractive index detector.",false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,"For analyzing non-UV absorbing substances, such as carbohydrates, lipids and polymers. This is also the detector of choice for gel permeation chromatography. The refractive index detector is one of the least sensitive LC detectors. It is very sensitive to changes in ambient temperature, pressure changes, flow-rate changes and can not be used for gradient elution. Despite these many disadvantages, this detector is extremely useful for detecting those compounds that are nonionic, do not adsorb in the UV, and do not fluoresce. There are many optical systems used in refractive index detectors but one of the most common is the differential refractive index detector.",WEB:<http://www.chromatography-online.org/HPLC/Refractive-Index/rs33.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01081,,,,,,refractive index detector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000583,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,refractive index detector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_1110125,assay measuring MHC ligand processing and presentation,ligand presentation|any method,A MHC ligand assay that determines what ligands are processed and loaded onto MHC molecules by eluting ligands and identifying them.,false,,,http://purl.obolibrary.org/obo/OBI_0002075,,,,,,,,,,,,,,,,,,,A MHC ligand assay that determines what ligands are processed and loaded onto MHC molecules by eluting ligands and identifying them.,IEDB,,,,,,assay measuring MHC ligand processing and presentation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110125,,,,,,,,,,,,,,,,,,,,,,,,ligand presentation|any method,,,,,,,,,,,,,,,,,,,,,,assay measuring MHC ligand processing and presentation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001655,phage display assay measuring binding of a B cell epitope:antibody complex,qualitative binding|phage display,A B cell epitope qualitative binding to antibody assay that uses a phage display binding assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001703,,,,,,,,,,,,,,,,,,,A B cell epitope qualitative binding to antibody assay that uses a phage display binding assay.,IEDB,,,,,,phage display assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001655,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|phage display,,,,,,,,,,,,,,,,,,,,,,phage display assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001928,selection,selection process,A planned process which results in the creation of group of entity from a larger group by the application of predefined criteria.,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,selection process,,,,,,,,,,,,,,,A planned process which results in the creation of group of entity from a larger group by the application of predefined criteria.,OBI,,,,,"this term refers to  a planned process and therefore is distinct from the notion of 'natural selection', a process covering the operation of natural causes by which those individuals of a species that are best adapted to the environment tend to be preserved and to transmit their characters, while those less adapted die out, so that in the course of generations the degree of adaptation to the environment tends progressively to increase. (as defined by Oxford English Dictionary)",selection,,"PMID: 24023800.  In this study, a set of eleven genes (VATP16, 60 S, UQCC, SMD3, EF1α, UBQ, SAND, GAPDH, ACT, PsaB, PTB2) was evaluated to identify reference genes during the first hours of interaction (6, 12, 18 and 24 hpi) between two V. vinifera genotypes and P. viticola. Two analyses were used for the selection of reference genes: direct comparison of susceptible, Trincadeira, and resistant, Regent, V. vinifera cultivars at 0 h, 6, 12, 18 and 24 hours post inoculation with P. viticola (genotype effect); and comparison of each genotype with mock inoculated samples during inoculation time-course (biotic stress effect). Three statistical methods were used, GeNorm, NormFinder, and BestKeeper, allowing to identify UBQ, EF1α and GAPDH as the most stable genes for the genotype effect.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001928,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,selection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000450,regulatory agency,,A regulatory agency is a organization that has responsibility over or for  the legislation (acts and regulations) for a given sector of the government.,false,,,http://purl.obolibrary.org/obo/OBI_0000245,,,,,,,,,,,,,,,,,,,A regulatory agency is a organization that has responsibility over or for  the legislation (acts and regulations) for a given sector of the government.,WEB: en.wikipedia.org/wiki/Regulator,,,,,,regulatory agency,,The US Environmental Protection Agency,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000450,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,regulatory agency,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP: OBI Biomaterial Branch,,
http://purl.obolibrary.org/obo/OBI_0000636,acquisition computer,,"A Computer used for NMR, can be divided into central processing unit (CPU), consisting of instruction, interpretation and arithmetic unit plus fast access memory, and peripheral devices such as bulk data storage and input and output devices (including, via the interface, the spectrometer). Under software control, the computer controls the RF pulses and gradients necessary to acquire data, and process the data to produce spectra or images. Note that devices such as the spectrometer may themselves incorporate small computers.",false,,,http://purl.obolibrary.org/obo/OBI_0400107,,,,,,,,,,,,,,,,,NMR instrument,,"A Computer used for NMR, can be divided into central processing unit (CPU), consisting of instruction, interpretation and arithmetic unit plus fast access memory, and peripheral devices such as bulk data storage and input and output devices (including, via the interface, the spectrometer). Under software control, the computer controls the RF pulses and gradients necessary to acquire data, and process the data to produce spectra or images. Note that devices such as the spectrometer may themselves incorporate small computers.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400013,,,,,,acquisition computer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000392,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000636,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,acquisition computer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000617,fluorine-induced chemiluminescence detector,,"A gas chromatographic detection system based on the low pressure, gas phase chemiluminescence of the reaction mixture of molecular fluorine with organo-sulfur, -selenium, and -tellurium compounds separated from (gas phase) headspace samples. This detector was originally developed in the research group of John Birks at the University of Colorado, USA and was manufactured and sold by Sievers Instruments (Boulder Colorado, USA). This system can be divided up into three parts: the chromatograph, transfer line, and reaction cell; PMT and photon counting electronics; and the molecular fluorine generator.",false,,,http://purl.obolibrary.org/obo/OBI_0000637,,,,,,,,,,,,,,,,,,,"A gas chromatographic detection system based on the low pressure, gas phase chemiluminescence of the reaction mixture of molecular fluorine with organo-sulfur, -selenium, and -tellurium compounds separated from (gas phase) headspace samples. This detector was originally developed in the research group of John Birks at the University of Colorado, USA and was manufactured and sold by Sievers Instruments (Boulder Colorado, USA). This system can be divided up into three parts: the chromatograph, transfer line, and reaction cell; PMT and photon counting electronics; and the molecular fluorine generator.",WEB:<http://www.shsu.edu/~chm_tgc/publications/JPP/chasteen.htm>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01087,,,,,,fluorine-induced chemiluminescence detector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000617,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,fluorine-induced chemiluminescence detector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000606,open tubular column,,"An open tubular column is a chromatography column in which the particles of the solid stationary phase or the support coated with a liquid stationary phase are concentrated on or along the inside tube wall leaving an open, unrestricted path for the mobile phase in the middle part of the tube.",false,,,http://purl.obolibrary.org/obo/OBI_0000038,,,,,,,,,,,,,,,,,,,"An open tubular column is a chromatography column in which the particles of the solid stationary phase or the support coated with a liquid stationary phase are concentrated on or along the inside tube wall leaving an open, unrestricted path for the mobile phase in the middle part of the tube.",WEB:<http:www.iupac.org/publications/pac/1993/pdf/6504x0819.pdf>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01219,,,,,,open tubular column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000606,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,open tubular column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0200008,hyperlog transformation,,"A hyperlog transformation ia a data transformation that, for each (one dimensional) real number input x, outputs an approximation (found, e.g. with the Newton's method) to a solution y of the equation EH(y)-x=0, where EH denotes an eh transformation.",false,,,http://purl.obolibrary.org/obo/OBI_0200169,,http://purl.obolibrary.org/obo/OBI_0200167,,,,,,,,,,,,,,,,,"A hyperlog transformation ia a data transformation that, for each (one dimensional) real number input x, outputs an approximation (found, e.g. with the Newton's method) to a solution y of the equation EH(y)-x=0, where EH denotes an eh transformation.","ARTICLE: Bagwell C.B. (2006), ""Hyperlog - a flexible log-like  transform for negative, zero, and positive valued data"", Cytometry A 64, 34-42.""|http://flowcyt.sourceforge.net/gating/latest.pdf",,,,,,hyperlog transformation,,This type of transformation is typically used in flow cytometry,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200008,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,hyperlog transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Ryan Brinkman|Joseph Spliden|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0001408,imprinting design,,"A study design where differences in genetic imprinting of maternally- and paternally-inherited chromosomes (e.g., due to in vivo differences in chemical modification and/or chromatin structure) are compared.",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A study design where differences in genetic imprinting of maternally- and paternally-inherited chromosomes (e.g., due to in vivo differences in chemical modification and/or chromatin structure) are compared.",MO_914 imprinting_design,,,,,,imprinting design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000131,,,,,,,,,,,,,,,,OBI:0001408,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,imprinting design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/PATO_0001421,alive,,A viability quality inhering in a bearer by virtue of the bearer's condition before death.,false,,,http://purl.obolibrary.org/obo/PATO_0001237,,,,,,,,,,,,,,,,,,,A viability quality inhering in a bearer by virtue of the bearer's condition before death.,,,,,,,alive,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001421,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,alive,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0001422,dead,,A viability quality inhering in a bearer by virtue of the cessation of the bearer's life.,false,,,http://purl.obolibrary.org/obo/PATO_0001237,,,,,,,,,,,,,,,,,,,A viability quality inhering in a bearer by virtue of the cessation of the bearer's life.,,,,,,,dead,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001422,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,dead,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001079,confocal microscope,,A microscope that is used to increase micrograph contrast and/or reconstruct three-dimensional images by using a spatial pinhole to eliminate out-of-focus light in specimens that are thicker than the focal plane.,false,,,http://purl.obolibrary.org/obo/OBI_0400169,,,,,,,,,,,,,,,,,,,A microscope that is used to increase micrograph contrast and/or reconstruct three-dimensional images by using a spatial pinhole to eliminate out-of-focus light in specimens that are thicker than the focal plane.,http://en.wikipedia.org/wiki/Confocal_microscopy,,,,,,confocal microscope,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001079,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,confocal microscope,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0000608,hydrogen generator,,A gas generator that generates hydrogen gas.,false,,,http://purl.obolibrary.org/obo/OBI_0000507,,,,,,,,,,,,,,,,,,,A gas generator that generates hydrogen gas.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01035,,,,,,hydrogen generator,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000608,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,hydrogen generator,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001508,sampling time measurement datum,time point,A time measurement datum when an observation is made or a sample is taken from a material as measured from some reference point.,false,,,http://purl.obolibrary.org/obo/IAO_0000416,,,,time point,,,,,,,,,,,,,,,A time measurement datum when an observation is made or a sample is taken from a material as measured from some reference point.,MO_738 timepoint,,,,,,sampling time measurement datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001508,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sampling time measurement datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0200146,subgraph modularity calculation,,A network subgraph quality calculation in which an input data set of subgraph in-degree and out-degree qualities is used to calculate the ratio of indegree to outdegree as a measure of modularity.,false,,,http://purl.obolibrary.org/obo/OBI_0200137,,,,,,,,,,,,,,,,,,,A network subgraph quality calculation in which an input data set of subgraph in-degree and out-degree qualities is used to calculate the ratio of indegree to outdegree as a measure of modularity.,PERSON: Richard Scheuermann,,,,,,subgraph modularity calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200146,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,subgraph modularity calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Richard Scheuermann,,
http://purl.obolibrary.org/obo/OBI_0001073,microtome knife maker,,A glass cutting and breaking device that is used to produce glass knives used in ultramicrotomy.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A glass cutting and breaking device that is used to produce glass knives used in ultramicrotomy.,PERSON: Erik Segerdell,,,,,,microtome knife maker,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000379,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001073,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,microtome knife maker,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0000343,inductive reasoning,,"a interpreting data that is used to ascribe properties or relations to types based on an observation instance (i.e., on a number of observations or experiences); or to formulate laws based on limited observations of recurring phenomenal patterns.",false,,,http://purl.obolibrary.org/obo/OBI_0000338,,,,,,,,,,,,,,,,,,,"a interpreting data that is used to ascribe properties or relations to types based on an observation instance (i.e., on a number of observations or experiences); or to formulate laws based on limited observations of recurring phenomenal patterns.",wikipedia: http://en.wikipedia.org/wiki/Inductive_reasoning,,,,,"BP: 10/22/122: After changing the parent class to drawing a conclusion *based on data* it is no longer clear that this class is needed; minimally it needs a better definition to distinguish it. 

Proposal is to obsolete. 

",inductive reasoning,,"Based on the observation that all lung cancer patients treated with aspirin in our clinical trial survived longer than the control group, we conclude by inductive reasining that aspirin has a therapeutic effect on lung cancer.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000428,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000343,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,inductive reasoning,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001057,high performance liquid chromatography instrument,,"A liquid chromatography instrument that consists of a reservoir of mobile phase, a pump, an injector, a separation column, and a detector. The pump (rather than gravity) provides the higher pressure required to propel the mobile phase and analyte through the densely packed column.",false,,,http://purl.obolibrary.org/obo/OBI_0001139,,,,,,,,,,,,,,,,,,,"A liquid chromatography instrument that consists of a reservoir of mobile phase, a pump, an injector, a separation column, and a detector. The pump (rather than gravity) provides the higher pressure required to propel the mobile phase and analyte through the densely packed column.",http://en.wikipedia.org/wiki/High_performance_liquid_chromatography,,,,,,high performance liquid chromatography instrument,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001057,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,high performance liquid chromatography instrument,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0400049,Guava EasyCyte Plus,,"A Guava_EasyCyte_Plus System is a flow_cytometer_analyser that includes a single 488 nm laser, and filters and PMTs to collect up to 4 fluorescent parameters. It includes a photodiode forward scatter collector and an optional photodiode for side scatter collection.Guava cytometers use aspiration instead of fluid systems to transport cells within the machine. The EasyCyte plus accepts 96 well plates as well as tubes. The Guava_EasyCyte_Plus cytometer is a small portable cytometer particularly useful for field measurement.",false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,,,,,,,,,,,,,,,,"A Guava_EasyCyte_Plus System is a flow_cytometer_analyser that includes a single 488 nm laser, and filters and PMTs to collect up to 4 fluorescent parameters. It includes a photodiode forward scatter collector and an optional photodiode for side scatter collection.Guava cytometers use aspiration instead of fluid systems to transport cells within the machine. The EasyCyte plus accepts 96 well plates as well as tubes. The Guava_EasyCyte_Plus cytometer is a small portable cytometer particularly useful for field measurement.",http://www.guavatechnologies.com/main/products/easycyte-new.cfm,,,,,,Guava EasyCyte Plus,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400049,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Guava EasyCyte Plus,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_1000036,cell lysate,lysate|lysed material,a cell lysate is a material entity which is output of a cell lysis process,false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,lysate|lysed material,,,,,,,,,,,,,,,a cell lysate is a material entity which is output of a cell lysis process,GROUP: PSI,,http://purl.obolibrary.org/obo/CL_0000000,,,"PRS:22-02-2008: is a material which has output_role during lysis protocol-application. 
old defintion: A mixture (collection) of cell components created by rupturing of the cell wall resulting from a lysis process",cell lysate,,The effect of vaccination with the lysate of heat-shocked tumor cells on nitric oxide production in BALB/c mice with fibrosarcoma tumor. Cell Biol Int. 2008 Jul;32(7):835-40. PMID: 18455932,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1000036,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0302894,,,cell lysate,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Susanna Sansone,,
http://purl.obolibrary.org/obo/PR_000025467,guanyl-specific ribonuclease T1,,A protein that is a translation product of the Aspergillus oryzae rntA gene or a 1:1 ortholog thereof.,false,,,http://purl.obolibrary.org/obo/PR_000000001,,,,,,,,,,,,,,,,,,,A protein that is a translation product of the Aspergillus oryzae rntA gene or a 1:1 ortholog thereof.,,,,,,,guanyl-specific ribonuclease T1,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PR:000025467,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pr.owl,,,,,,,,,,,,,,,,,,,guanyl-specific ribonuclease T1,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001051,DNA extract,,The output of an extraction process in which DNA molecules are purified in order to exclude DNA from organellas.,false,,,http://purl.obolibrary.org/obo/OBI_0001010,,,,,,,,,,,,,,,,,,,The output of an extraction process in which DNA molecules are purified in order to exclude DNA from organellas.,Group: UPenn group,,,,,,DNA extract,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,http://purl.obolibrary.org/obo/CHEBI_16991,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001051,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000257,,,DNA extract,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jie Zheng,,
http://purl.obolibrary.org/obo/OBI_0001922,microRNA profiling by high throughput sequencing assay,microRNA-seq assay|microRNA-seq|miRNA-seq,A RNA-seq assay in which high throughput sequencing technology is used to analyse the microRNA component of the transcriptome.,false,,,http://purl.obolibrary.org/obo/OBI_0001926|http://purl.obolibrary.org/obo/OBI_0001271,,,,microRNA-seq assay|microRNA-seq|miRNA-seq,,,,,,,,,,,,,,,A RNA-seq assay in which high throughput sequencing technology is used to analyse the microRNA component of the transcriptome.,http://www.ebi.ac.uk/efo/EFO_0002896,,,,,,microRNA profiling by high throughput sequencing assay,,"Juhlia et al. MicroRNA expression profiling reveals miRNA families regulating 
specific biological pathways in mouse frontal cortex and hippocampus. PLoS One. 2011;6(6). [PMID: 21731767]",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000711,,,,,,,,,,,,,,,,OBI:0001922,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,microRNA profiling by high throughput sequencing assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0400028,CytoSence,,"A CytoSense is a flow_cytometer_analyser manufactured by Cyto Buoy Inc. They are a single laser, multi parameter instrument. Various types of micro-laser are offered; available measuring parameters are forward light scatter, side scatter, and fluorescence (max. 9 colour bands). The current series have 5 parameters. The CytoSense is the basic instrument, which can be used for normal laboratory applications, as well as for autonomous monitoring with internal data logging or direct data transmission. The special instrument design and its splashproof housing allow operation on moving platforms and outdoor sites.",false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,,,,,,,,,,,,,,,,"A CytoSense is a flow_cytometer_analyser manufactured by Cyto Buoy Inc. They are a single laser, multi parameter instrument. Various types of micro-laser are offered; available measuring parameters are forward light scatter, side scatter, and fluorescence (max. 9 colour bands). The current series have 5 parameters. The CytoSense is the basic instrument, which can be used for normal laboratory applications, as well as for autonomous monitoring with internal data logging or direct data transmission. The special instrument design and its splashproof housing allow operation on moving platforms and outdoor sites.",http://www.cytobuoy.com/,,,,,,CytoSence,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400028,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CytoSence,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0200032,K-fold cross validation method,,"K-fold cross-validation randomly partitions the original sample into K subsamples. Of the K subsamples, a single subsample is retained as the validation data for testing the model, and the remaining K - 1 subsamples are used as training data. The cross-validation process is then repeated K times (the folds), with each of the K subsamples used exactly once as the validation data. The K results from the folds then can be averaged (or otherwise combined) to produce a single estimation. The advantage of this method over repeated random sub-sampling is that all observations are used for both training and validation, and each observation is used for validation exactly once. 10-fold cross-validation is commonly used",false,,,http://purl.obolibrary.org/obo/OBI_0000792,,http://purl.obolibrary.org/obo/OBI_0200188,,,,,,,,,,,,,,,,,"K-fold cross-validation randomly partitions the original sample into K subsamples. Of the K subsamples, a single subsample is retained as the validation data for testing the model, and the remaining K - 1 subsamples are used as training data. The cross-validation process is then repeated K times (the folds), with each of the K subsamples used exactly once as the validation data. The K results from the folds then can be averaged (or otherwise combined) to produce a single estimation. The advantage of this method over repeated random sub-sampling is that all observations are used for both training and validation, and each observation is used for validation exactly once. 10-fold cross-validation is commonly used",Tina Boussard,,,,,,K-fold cross validation method,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200032,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,K-fold cross validation method,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0002084,transcription cofactor activity region identification by ChIP-Seq assay,chromatin modifier binding site identification by ChIP-Seq assay,"A ChIP-seq assay to identify regions of chromatin bound to a chromatin modifying protein, e.g. a histone acetyltransferase.",false,,,http://purl.obolibrary.org/obo/OBI_0000716,,,,chromatin modifier binding site identification by ChIP-Seq assay,,,,,,,,,,,,,,,"A ChIP-seq assay to identify regions of chromatin bound to a chromatin modifying protein, e.g. a histone acetyltransferase.","FaceBase, PMID 19212405",,,,,Tracker item: 782,transcription cofactor activity region identification by ChIP-Seq assay,,"PMID 19212405: ""we present the results of chromatin immunoprecipitation with the enhancer-associated protein p300 followed by massively parallel sequencing, and map several thousand in vivo binding sites of p300 in mouse embryonic forebrain, midbrain and limb tissue""",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002084,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,transcription cofactor activity region identification by ChIP-Seq assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Paul D. Thomas, Yang Chai",,
http://purl.obolibrary.org/obo/IAO_0000595,software script,," A software script is software whose instructions can be executed using a software 
interpreter.",false,,,http://purl.obolibrary.org/obo/IAO_0000010,,,,,,,,,,,,,,,,,,," A software script is software whose instructions can be executed using a software 
interpreter.",http://code.google.com/p/information-artifact-ontology/issues/detail?id=80,,,,,,software script,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000595,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,software script,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot|PERSON: Michel Dumontier,,
http://purl.obolibrary.org/obo/OBI_0001060,spot cutter,,A robotic device that is used to excise spots from gels.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A robotic device that is used to excise spots from gels.,PERSON: Erik Segerdell,,,,,,spot cutter,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000379,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001060,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,spot cutter,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0000744,material sampling process,,A specimen gathering process with the objective to obtain a specimen that is representative of the input material entity,false,,,http://purl.obolibrary.org/obo/OBI_0000659,,,,,,,,,,,,,,,,,,,A specimen gathering process with the objective to obtain a specimen that is representative of the input material entity,,,,,,,material sampling process,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000744,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,material sampling process,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001569,purified MHC direct binding assay measuring binding off rate [koff] of a MHC:ligand complex using fluorescence detection,off rate|purified MHC/direct/fluorescence|1/s,A purified MHC ligand binding off rate measurement (koff) determination assay that uses fluorescence detection to measure direct ligand binding.,false,,,http://purl.obolibrary.org/obo/OBI_0001499|http://purl.obolibrary.org/obo/OBI_0001993,,,,,,,,,,,,,,,,,,,A purified MHC ligand binding off rate measurement (koff) determination assay that uses fluorescence detection to measure direct ligand binding.,IEDB,,,,,,purified MHC direct binding assay measuring binding off rate [koff] of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001569,,,,,,,,,,,,,,,,,,,,,,,,off rate|purified MHC/direct/fluorescence|1/s,,,,,,,,,,,,,,,,,,,,,,purified MHC direct binding assay measuring binding off rate [koff] of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/IAO_0000181,Venn diagram,,"A Venn diagram is a report graph showing all hypothetically possible
logical relations between a finite collection of sets.",false,,,http://purl.obolibrary.org/obo/IAO_0000038,,,,,,,,,,,,,,,,,,,"A Venn diagram is a report graph showing all hypothetically possible
logical relations between a finite collection of sets.",WEB: http://en.wikipedia.org/wiki/Venn_diagram,,,,,,Venn diagram,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000181,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Venn diagram,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:James Malone|PERSON:Chris Stoeckert|PERSON:Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0001942,grant agency,funding organization,An organization that provides funding support for projects such as investigations.,false,,,http://purl.obolibrary.org/obo/OBI_0000245,,,,funding organization,,,,,,,,,,,,,,,An organization that provides funding support for projects such as investigations.,NIAID GSCID-BRC metadata working group,,,,,,grant agency,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001942,,,,,,,,,,,,,,,,,,,,"'funding organization'
http://vivoweb.org/ontology/core#FundingOrganization",,,,,,,,,,,,,,,,,,,,,,,,,,grant agency,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Jie Zheng, Chris Stoeckert",,
http://purl.obolibrary.org/obo/OBI_0000437,analyte measurement objective,,an assay objective to determine the presence or concentration of an analyte in the evaluant,false,,,http://purl.obolibrary.org/obo/OBI_0000441,,,,,,,,,,,,,,,,,,,an assay objective to determine the presence or concentration of an analyte in the evaluant,PPPB branch,,,,,,analyte measurement objective,,The objective to measure the concentration of glucose in a blood sample,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000437,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,analyte measurement objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000471,study design execution,,a planned process that realizes the concretization of a study design,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,"6/11/9: edited at workshop. Used to be: study design execution is a process with the objective to generate data according to a concretized study design. The execution of a study design is part of an investigation, and minimally consists of an assay or data transformation.",,a planned process that realizes the concretization of a study design,branch derived,,,,,removed axiom has_part some (assay or 'data transformation') per discussion on protocol application mailing list to improve reasoner performance. The axiom is still desired.,study design execution,,"injecting a mouse with PBS solution, weighing it, and recording the weight according to a study design.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000471,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/obi.owl,,,,,,,,,,,,,,,,,,,study design execution,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0400044,flow cytometer,,"A flow_cytometer is an instrument for counting, examining and sorting microscopic particles in suspension. It allows simultaneous multiparametric analysis of the physical and/or chemical characteristics of single cells flowing through an optical and/or electronic detection apparatus. A flow cytometer is an instrument that can be used to quantitatively measure the properties of individual cells in a flowing medium.",false,,,http://purl.obolibrary.org/obo/OBI_0400137,,,,,,,,,,,,,,,,,,,"A flow_cytometer is an instrument for counting, examining and sorting microscopic particles in suspension. It allows simultaneous multiparametric analysis of the physical and/or chemical characteristics of single cells flowing through an optical and/or electronic detection apparatus. A flow cytometer is an instrument that can be used to quantitatively measure the properties of individual cells in a flowing medium.",http://en.wikipedia.org/wiki/Flow_cytometer,,,,,,flow cytometer,,FACS Calibur,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0400153|http://purl.obolibrary.org/obo/OBI_0400078,,,,,,,,,,,,,,,,OBI:0400044,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,flow cytometer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0001924,micrococcal nuclease digestion followed by high throughput sequencing assay,MNase-seq assay|MNase-seq,An assay to identify nucleosome positioning by genome wide sequencing of regions senstative to digestion by micrococal nuclease,false,,,http://purl.obolibrary.org/obo/OBI_0600047,,http://purl.obolibrary.org/obo/OBI_0001398,,MNase-seq assay|MNase-seq,,,,,,,,,,,,,JZ: should be inferred as 'DNA sequencing'. Will check in the future.,,An assay to identify nucleosome positioning by genome wide sequencing of regions senstative to digestion by micrococal nuclease,Johnson et al. Flexibility and constraint in the nucleosome core landscape of Caenorhabditis elegans chromatin. Genome Res. 2006 Dec;16(12):1505-16. [PMID:17038564],,,,,,micrococcal nuclease digestion followed by high throughput sequencing assay,,Cui et al.Genome-wide approaches to determining nucleosome occupancy in metazoans using MNase-Seq. Methods Mol Biol. 2012;833:413-9. [PMID:22183607],,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0600023|http://purl.obolibrary.org/obo/OBI_0000711,http://purl.obolibrary.org/obo/OBI_0400103,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001573,,,OBI:0001924,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,micrococcal nuclease digestion followed by high throughput sequencing assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001939,genome coverage,,"A data item that is the total number of bases in reads, divided by genome size, assumed to be the reference size (for instance of 3.10 Gb for human and 2.73 Gb for mouse) and refers to the percentage of the genome that is contained in the assembly based on size estimates; these are usually based on cytological techniques. Genome coverage of 90–95% is generally considered to be good, as most genomes contain a considerable fraction of repetitive regions that are difficult to sequence. So it is not a cause for concern if the genome coverage of an assembly is a bit less than 100%.",false,,,http://purl.obolibrary.org/obo/IAO_0000027,,,,,,,,,,,,,,,,,,,"A data item that is the total number of bases in reads, divided by genome size, assumed to be the reference size (for instance of 3.10 Gb for human and 2.73 Gb for mouse) and refers to the percentage of the genome that is contained in the assembly based on size estimates; these are usually based on cytological techniques. Genome coverage of 90–95% is generally considered to be good, as most genomes contain a considerable fraction of repetitive regions that are difficult to sequence. So it is not a cause for concern if the genome coverage of an assembly is a bit less than 100%.","A beginner's guide to eukaryotic genome annotation. Yandell M, Ence D.
Nat Rev Genet. 2012 Apr 18;13(5):329-42. doi: 10.1038/nrg3174.
PMID: 22510764",,,,,,genome coverage,,"Gigascience. 2012 Dec 27;1(1):18. doi: 10.1186/2047-217X-1-18.
PMID: 23587118. 

""The genome coverage increased from 81.16% to 93.91%""",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001939,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/SO_0001248,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001872,,,genome coverage,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Alejandra Gonzalez-Beltran|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001701,antigen inhibition assay measuring binding of a B cell epitope:antibody complex,qualitative binding|antigen inhibition,A B cell epitope qualitative binding to antibody assay that measures the ability of an antigen to inhibit antibody binding to a known ligand.,false,,,http://purl.obolibrary.org/obo/OBI_0001703,,,,,,,,,,,,,,,,,,,A B cell epitope qualitative binding to antibody assay that measures the ability of an antigen to inhibit antibody binding to a known ligand.,IEDB,,,,,,antigen inhibition assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001701,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|antigen inhibition,,,,,,,,,,,,,,,,,,,,,,antigen inhibition assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_1110156,ELISA measuring epitope specific interleukin-10 production by T cells,IL-10 release|ELISA,An assay of epitope specific interleukin-10 production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001209,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-10 production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific interleukin-10 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110156,,,,,,,,,,,,,,,,,,,,,,,,IL-10 release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific interleukin-10 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001441,proteomic profiling by array design,,"A study design in which proteins in a sample are detected, quantified or otherwise analysed, e.g. antibody profiling using an array based technology",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A study design in which proteins in a sample are detected, quantified or otherwise analysed, e.g. antibody profiling using an array based technology",Group: ArrayExpress production team,,,,,,proteomic profiling by array design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000131,,,,,,,,,,,,,,,,OBI:0001441,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,proteomic profiling by array design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/GO_0001906,cell killing,,"Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.",false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,"Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.",,,,,,,cell killing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0001906,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,cell killing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0302901,obsolete_activation,,"a process by which a material entity status is modified and conferred a capability of reacting
(this sounds like a circular definition , hugh!)",true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,"a process by which a material entity status is modified and conferred a capability of reacting
(this sounds like a circular definition , hugh!)",OBI-Branch,,,,,"Alan Ruttenberg 2010/11/22: After OBI call, this is too broad a term, and in any case would be in the scope of GO|See tracker:
https://sourceforge.net/tracker/index.php?func=detail&aid=3302925&group_id=177891&atid=886178",obsolete_activation,,PMID: 18566411.Activation of the JAK/STAT-1 Signaling Pathway by IFN-{gamma} Can Down-Regulate Functional Expression of the MHC Class I-Related Neonatal Fc Receptor for IgG.J Immunol. 2008 Jul 1;181(1):449-63.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000124,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,OBI:0302901,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_activation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001404,genetic characteristics information,,"a data item that is about genetic material including polymorphisms, disease alleles, and haplotypes.",false,,,http://purl.obolibrary.org/obo/IAO_0000027,,,,,,,,,,,,,,,,,"MO definition:
The genotype of the individual organism from which the biomaterial was derived. Individual genetic characteristics include polymorphisms, disease alleles, and haplotypes.

examples in ArrayExpress
wild_type
MutaMouse (CD2F1 mice with lambda-gt10LacZ integration)
AlfpCre; SNF5 flox/knockout
p53 knock out
C57Bl/6 gp130lox/lox MLC2vCRE/+
fer-15; fem-1
df/df
pat1-114/pat1-114 ade6-M210/ade6-M216 h+/h+ (cells are diploid)
",,"a data item that is about genetic material including polymorphisms, disease alleles, and haplotypes.",MO_66 IndividualGeneticCharacteristics,,,,,,genetic characteristics information,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001404,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,genetic characteristics information,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_1110026,host of immune response,,An organism in which an immune response process occurs.,false,,,http://purl.obolibrary.org/obo/OBI_0100026,,,,,,,,,,,,,,,,,,,An organism in which an immune response process occurs.,IEDB,,,,,"In immune response processes in the context of infectious diseases and allergy, there are often multiple organisms involved, which requires calling out the 'host'. This terminology is expanded to allergy, cancer and  transplantation.",host of immune response,,A mouse that is vaccinated with a peptide and develops protective immunity. A human exposed to bacteria that are killed by pre-existing immune responses.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110026,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,host of immune response,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001633,purified material,,A material entity that is generated by a purification process in which an input material is separated to obtain a fraction with a higher concentration of a desired component,false,,,http://purl.obolibrary.org/obo/OBI_0000047|http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,A material entity that is generated by a purification process in which an input material is separated to obtain a fraction with a higher concentration of a desired component,OBI conference call,,,,,,purified material,,A mixture of peptide molecules that has been run through an HPLC column to remove 65,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001633,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,purified material,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP: OBI call ,,
http://purl.obolibrary.org/obo/OBI_0002014,DNA methylation profiling by ChIP-chip assay,DNA methylation ChIP-chip,A ChIP-chip assay that identifies sites of DNA methylation.,false,,,http://purl.obolibrary.org/obo/OBI_0001248|http://purl.obolibrary.org/obo/OBI_0002020,,http://purl.obolibrary.org/obo/OBI_0001234,,DNA methylation ChIP-chip,,,,,,,,,,,,,,,A ChIP-chip assay that identifies sites of DNA methylation.,Penn group,,,,,,DNA methylation profiling by ChIP-chip assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002014,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNA methylation profiling by ChIP-chip assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Beta Cell Biology Consoritum,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001055,spinning-disk confocal microscope,,"A confocal microscope that uses a Nipkow disk, a mechanical, geometrically operating image scanning device.",false,,,http://purl.obolibrary.org/obo/OBI_0001079,,,,,,,,,,,,,,,,,,,"A confocal microscope that uses a Nipkow disk, a mechanical, geometrically operating image scanning device.",http://en.wikipedia.org/wiki/Nipkow_disk,,,,,,spinning-disk confocal microscope,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001055,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,spinning-disk confocal microscope,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001341,cell culture analyte detection bioassay measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells,GM-CSF release|bioassay,An assay of epitope specific granulocyte macrophage colony stimulating factor production by T cells that uses a cell culture analyte detection bioassay.,false,,,http://purl.obolibrary.org/obo/OBI_0001233,,,,,,,,,,,,,,,,,,,An assay of epitope specific granulocyte macrophage colony stimulating factor production by T cells that uses a cell culture analyte detection bioassay.,IEDB,,,,,,cell culture analyte detection bioassay measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001341,,,,,,,,,,,,,,,,,,,,,,,,GM-CSF release|bioassay,,,,,,,,,,,,,,,,,,,,,,cell culture analyte detection bioassay measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001715,obsolete B cell epitope competitive binding assay,competitive binding assay,A competitive inhibition of binding assay using a assay,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,A competitive inhibition of binding assay using a assay,IEDB (QTT),,,,,,obsolete B cell epitope competitive binding assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,OBI:0001715,,,,,,,,,,,,,,,,,,,,,,,,competitive binding assay,,,,,,,,,,,,,,,,,,,,,,obsolete B cell epitope competitive binding assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0600045,3D structure determination assay,,An assay that determines the 3-dimensional configuration of an input material.,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,An assay that determines the 3-dimensional configuration of an input material.,IEDB,,,,,,3D structure determination assay,,The use of X-ray crystallography to determine the 3D coordinates of atoms in a protein.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600045,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,3D structure determination assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001460,genetic modification design,,"A study design in which an organism(s) is studied that has had genetic material removed, rearranged, mutagenized or added, such as in a knock out.",false,,,http://purl.obolibrary.org/obo/OBI_0000115,,,,,,,,,,,,,,,,,,,"A study design in which an organism(s) is studied that has had genetic material removed, rearranged, mutagenized or added, such as in a knock out.",MO_447 genetic_modification_design,,,,,,genetic modification design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000015,,,,,,,,,,,,,,,,OBI:0001460,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,genetic modification design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001731,surface plasmon resonance assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex,dissociation constant KD|surface plasmon resonance (SPR)|nM,A B cell epitope equilibrium dissociation constant (KD) determination assay that uses a surface plasmon resonance assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001708,,,,,,,,,,,,,,,,,,,A B cell epitope equilibrium dissociation constant (KD) determination assay that uses a surface plasmon resonance assay.,IEDB,,,,,,surface plasmon resonance assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001731,,,,,,,,,,,,,,,,,,,,,,,,dissociation constant KD|surface plasmon resonance (SPR)|nM,,,,,,,,,,,,,,,,,,,,,,surface plasmon resonance assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000529,JEOL NMR probe,,An NMR probe that is manufactured by JEOL.,false,,,http://purl.obolibrary.org/obo/OBI_0000516,,,,,,,,,,,,,,,,,NMR device,,An NMR probe that is manufactured by JEOL.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400232,,,,,,JEOL NMR probe,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000529,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,JEOL NMR probe,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0200107,partial least square discriminant analysis,PLS-DA,"PLS Discriminant Analysis (PLS-DA) is a discriminant analysis performed in order to sharpen the separation between groups of observations, by hopefully rotating PCA (Principal Components Analysis) components such that a maximum separation among classes is obtained, and to understand which variables carry the class separating information.",false,,,http://purl.obolibrary.org/obo/OBI_0200106,,,,PLS-DA,,,,,,,,,,,,,,,"PLS Discriminant Analysis (PLS-DA) is a discriminant analysis performed in order to sharpen the separation between groups of observations, by hopefully rotating PCA (Principal Components Analysis) components such that a maximum separation among classes is obtained, and to understand which variables carry the class separating information.",WEB: http://www.camo.com/rt/Resources/pls-da.html,,,,,,partial least square discriminant analysis,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200107,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,partial least square discriminant analysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0000967,container,,A device that can be used to restrict the location of material entities over time,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A device that can be used to restrict the location of material entities over time,,,,,,"03/21/2010: Added to allow classification of children (similar to what we want to do for 'measurement device'. Lookint at what classifies here, we may want to reconsider a contain function assigned to a part of an entity is necessarily also a function of the whole (e.g. is a centrifuge a container because it has test tubes as parts?)",container,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000967,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,container,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000378,filter function,,A filter function is a function to prevent the flow of certain entities based on a quality or qualities of the entity while allowing entities which have different qualities to pass through,false,,,http://purl.obolibrary.org/obo/OBI_0000372,,,,,,,,,,,,,,,,,,,A filter function is a function to prevent the flow of certain entities based on a quality or qualities of the entity while allowing entities which have different qualities to pass through,,,,,,,filter function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000378,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,filter function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Frank Gibson,,
http://purl.obolibrary.org/obo/OBI_0600026,longitudinal mass measurement assay,,A process in which the mass of a material is measured at two or more time points,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,http://purl.obolibrary.org/obo/OBI_0000441,,,,,,,,,,,,,,,,,A process in which the mass of a material is measured at two or more time points,OBI branch derived,,,,,,longitudinal mass measurement assay,,The comparison of the weight of vaccinated and non-vaccinated mice after infection with influenza A over 6 weeks post-infection,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100026,http://purl.obolibrary.org/obo/IAO_0000109,,,OBI:0600026,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,longitudinal mass measurement assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0302902,immobilization,,immbolization is a process by which material entity become (possibly covalently but not necessarily) attached to the surface of another material entity used a substratum.,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,immbolization is a process by which material entity become (possibly covalently but not necessarily) attached to the surface of another material entity used a substratum.,OBI-Branch,,,,,,immobilization,,PMID: 18562258. The immobilization of proteins on biodegradable fibers via biotin-streptavidin bridges.Acta Biomater. 2008 May 23.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302902,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,immobilization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/IAO_0000019,obsolete2_binary digital entity,,A binary digital entity is a digital entity that is encoded in a way that is not easily human readable and that contains other than text characters.,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,A binary digital entity is a digital entity that is encoded in a way that is not easily human readable and that contains other than text characters.,group:OBI|OBI_0000244,,,,,"3/22/2009 Alan Ruttenberg, obsoleted per http://groups.google.com/group/information-ontology/browse_thread/thread/789ad4b7708d5cf4
Superclass was 'digital entity'|digital_entity",obsolete2_binary digital entity,,"MS Word document, ZIP file, DICOM file, JPEG file",,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,IAO:0000019,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete2_binary digital entity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0001693,in vivo assay measuring B cell epitope specific tolerance induction,tolerance|in vivo assay,An efficacy of B cell epitope intervention experiment that uses a tolerance induction intervention experiment.,false,,,http://purl.obolibrary.org/obo/OBI_0001698,,,,,,,,,,,,,,,,,,,An efficacy of B cell epitope intervention experiment that uses a tolerance induction intervention experiment.,IEDB,,,,,,in vivo assay measuring B cell epitope specific tolerance induction,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001693,,,,,,,,,,,,,,,,,,,,,,,,tolerance|in vivo assay,,,,,,,,,,,,,,,,,,,,,,in vivo assay measuring B cell epitope specific tolerance induction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000836,test tube,collection tube|sample tube,"A test tube is a device consisting of a glass or plastic tubing, open at the top, usually with a rounded U-shaped bottom which has the function to contain material",false,,,http://purl.obolibrary.org/obo/OBI_0000967,,,,collection tube|sample tube,,,,,,,,,,,,,,,"A test tube is a device consisting of a glass or plastic tubing, open at the top, usually with a rounded U-shaped bottom which has the function to contain material",http://en.wikipedia.org/wiki/Test_tube,,,,,,test tube,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000370,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000836,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,test tube,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001543,purified MHC direct binding assay measuring equilibrium dissociation constant [KD] of a MHC:ligand complex approximated by EC50 using fluorescence detection,dissociation constant KD (~EC50)|purified MHC/direct/fluorescence|nM,A purified MHC ligand binding equilibrium dissociation constant (KD) determination assay that uses fluorescence detection to measure direct ligand binding and provides EC50 values determined under assay conditions where the EC50 approximates a KD value. ,false,,,http://purl.obolibrary.org/obo/OBI_0001988|http://purl.obolibrary.org/obo/OBI_0001499,,,,,,,,,,,,,,,,,,,A purified MHC ligand binding equilibrium dissociation constant (KD) determination assay that uses fluorescence detection to measure direct ligand binding and provides EC50 values determined under assay conditions where the EC50 approximates a KD value. ,IEDB,,,,,,purified MHC direct binding assay measuring equilibrium dissociation constant [KD] of a MHC:ligand complex approximated by EC50 using fluorescence detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001501,,,,,,,,,,,,,,,,OBI:0001543,,,,,,,,,,,,,,,,,,,,,,,,dissociation constant KD (~EC50)|purified MHC/direct/fluorescence|nM,,,,,,,,,,,,,,,,,,,,,,purified MHC direct binding assay measuring equilibrium dissociation constant [KD] of a MHC:ligand complex approximated by EC50 using fluorescence detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001122,diffractometer,,A measurement device for analyzing the structure of a material from the scattering pattern produced when a beam of radiation or particles (e.g. X rays or neutrons) interacts with it.,false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,A measurement device for analyzing the structure of a material from the scattering pattern produced when a beam of radiation or particles (e.g. X rays or neutrons) interacts with it.,http://en.wikipedia.org/wiki/Diffractometer,,,,,,diffractometer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,diffractometer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001888,sequencing facility contact person,Sequencing Facility Contact Name,A person who is the contact representative at the sequencing facility,false,,,http://purl.obolibrary.org/obo/NCBITaxon_9606,,,,,,,,,,,,,,,,,,,A person who is the contact representative at the sequencing facility,NIAID GSCID-BRC metadata working group,,,,,,sequencing facility contact person,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001888,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sequencing facility contact person,,,,,,Sequencing Facility Contact Name,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_1110099,L cell line,,A cell line derived from mouse fibroblasts.,false,,,http://purl.obolibrary.org/obo/CLO_0009828,,,,,,,,,,,,,,,,,,,A cell line derived from mouse fibroblasts.,http://www.biotech.ist.unige.it/cldb/cl3075.html|IEDB,,,,,,L cell line,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110099,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,L cell line,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001835,cytometric bead array assay measuring epitope specific interleukin-18 production by T cells,IL-18 release|cytometric bead array,An assay of epitope specific interleukin-18 production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001380,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-18 production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific interleukin-18 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001835,,,,,,,,,,,,,,,,,,,,,,,,IL-18 release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific interleukin-18 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001403,ChIP-chip design,ChIP-on-chip design,A study design which aims to identify protein binding sites in genomic DNA by a combination of chromatin immunoprecipitation and DNA microarray (chip) assays.,false,,,http://purl.obolibrary.org/obo/OBI_0001425,,,,ChIP-on-chip design,,,,,,,,,,,,,,,A study design which aims to identify protein binding sites in genomic DNA by a combination of chromatin immunoprecipitation and DNA microarray (chip) assays.,MO_933 binding_site_identification_design,,,,,,ChIP-chip design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001398,,,,,,,,,,,,,,,,OBI:0001403,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ChIP-chip design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001142,dye swap quality control role,,a reference substance role that is borne by a material entity used in a dye swap design experiment for quality control or data normalization purposes,false,,,http://purl.obolibrary.org/obo/OBI_0000025,,,,,,,,,,,,,,,,,,,a reference substance role that is borne by a material entity used in a dye swap design experiment for quality control or data normalization purposes,MO_524 dye_swap_quality_control,,,,,,dye swap quality control role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001142,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001143,,,,,,,,,,,,,,,,,dye swap quality control role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/NCBITaxon_197562,Pancrustacea,,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_1206794,,,,,,,,,,,,,,,,,,,,,,,,,,Pancrustacea,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:197562,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Pancrustacea,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200177,center calculation objective,,A center calculation objective is a data transformation objective where the aim is to calculate the center of an input data set.,false,,,http://purl.obolibrary.org/obo/OBI_0200166,,,,,,,,,,,,,,,,,,,A center calculation objective is a data transformation objective where the aim is to calculate the center of an input data set.,PERSON: James Malone,,,,,,center calculation objective,,A mean calculation which has center calculation objective is a data transformation in which the center of the input data is discovered through the calculation of a mean average.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200177,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,center calculation objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/IAO_0000317,methods section,,A part of a publication about an investigation that is about the study design of the investigation,false,,,http://purl.obolibrary.org/obo/IAO_0000314,,,,,,,,,,,,,,,,,,,A part of a publication about an investigation that is about the study design of the investigation,,,,,,,methods section,,The section labelled 'Methods' or 'Materials and Methods' in a typical scientific journal article.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000317,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,methods section,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0001561,cell bound MHC direct binding assay measuring half maximal effective concentration [EC50] of a MHC:ligand complex using fluorescence detection,half maximal effective concentration (EC50)|cellular MHC/direct/fluorescence|nM,A cell bound MHC ligand binding half maximal effective concentration (EC50) determination assay that uses fluorescence detection to measure direct ligand binding.,false,,,http://purl.obolibrary.org/obo/OBI_0001991|http://purl.obolibrary.org/obo/OBI_0001499,,,,,,,,,,,,,,,,,,,A cell bound MHC ligand binding half maximal effective concentration (EC50) determination assay that uses fluorescence detection to measure direct ligand binding.,IEDB,,,,,,cell bound MHC direct binding assay measuring half maximal effective concentration [EC50] of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001561,,,,,,,,,,,,,,,,,,,,,,,,half maximal effective concentration (EC50)|cellular MHC/direct/fluorescence|nM,,,,,,,,,,,,,,,,,,,,,,cell bound MHC direct binding assay measuring half maximal effective concentration [EC50] of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001672,gene knock-down assay,,is an assay which transiently disrupts gene transcripts by expressing antisense RNA constructs or delivering RNA interfering molecules in cells.,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,is an assay which transiently disrupts gene transcripts by expressing antisense RNA constructs or delivering RNA interfering molecules in cells.,PMID:17430206,,,,,,gene knock-down assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001672,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,gene knock-down assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra; Marcus Chibucos,,
http://purl.obolibrary.org/obo/OBI_1110007,administration in vivo with infectious agent,,is an administration of an infectious agent to a host organism,false,,,http://purl.obolibrary.org/obo/OBI_0600007,,,,,,,,,,,,,,,,,,,is an administration of an infectious agent to a host organism,IEDB,,,,,,administration in vivo with infectious agent,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110007,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,administration in vivo with infectious agent,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001475,in vivo assay measuring T cell epitope specific protection from infectious challenge based on pathogen burden,pathogen burden after challenge|in vivo assay,A T cell epitope in vivo intervention experiment that uses a protection from challenge in vivo intervention experiment based on pathogen burden.,false,,,http://purl.obolibrary.org/obo/OBI_0002073,,,,,,,,,,,,,,,,,,,A T cell epitope in vivo intervention experiment that uses a protection from challenge in vivo intervention experiment based on pathogen burden.,IEDB,,,,,,in vivo assay measuring T cell epitope specific protection from infectious challenge based on pathogen burden,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001475,,,,,,,,,,,,,,,,,,,,,,,,pathogen burden after challenge|in vivo assay,,,,,,,,,,,,,,,,,,,,,,in vivo assay measuring T cell epitope specific protection from infectious challenge based on pathogen burden,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000808,spectrolyse heparin antifactor-Xa assay,,"A Spectrolyse Heparin (Xa) assay is intended for the quantitative determination of therapeutic Heparin in human plasma.

The principle inhibitor of Thrombin, Factor Xa and other coagulation serine proteases in plasma is Antithrombin III. The rate of inhibition, under normal conditions, is slow, but can be increased several thousand-fold by Heparin. This mechanism accounts for the anticoagulant effect of Heparin. Low Molecular Weight Therapeutic Heparin (LMWH) preparations appear to catalyze the reaction between Factor Xa and Antithrombin III more readily than the reaction between Thrombin and Antithrombin III while standard Heparin catalyzes both reactions equally. The Factor Xa inhibition test is the most useful test for assaying the widest variety of therapeutic Heparin preparations. In this method, when both Factor Xa and Antithrombin III are present in excess, the rate of Factor Xa inhibition is directly proportional to the Heparin concentration. The residual Factor Xa activity, measured with a Factor Xa-specific chromogenic substrate, is inversely proportional to the Heparin concentration.",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,,"A Spectrolyse Heparin (Xa) assay is intended for the quantitative determination of therapeutic Heparin in human plasma.

The principle inhibitor of Thrombin, Factor Xa and other coagulation serine proteases in plasma is Antithrombin III. The rate of inhibition, under normal conditions, is slow, but can be increased several thousand-fold by Heparin. This mechanism accounts for the anticoagulant effect of Heparin. Low Molecular Weight Therapeutic Heparin (LMWH) preparations appear to catalyze the reaction between Factor Xa and Antithrombin III more readily than the reaction between Thrombin and Antithrombin III while standard Heparin catalyzes both reactions equally. The Factor Xa inhibition test is the most useful test for assaying the widest variety of therapeutic Heparin preparations. In this method, when both Factor Xa and Antithrombin III are present in excess, the rate of Factor Xa inhibition is directly proportional to the Heparin concentration. The residual Factor Xa activity, measured with a Factor Xa-specific chromogenic substrate, is inversely proportional to the Heparin concentration.",WEB:http://www.kordia.nl/en/product/hemostasis/specialty_kits__reagens/598/spectrolyse_heparin_anti_xa@2009/08/06,,,,,2009/10/18 Alan Ruttenberg. This assay was added during the fucoidan use case exercise but still needs to be fleshed out. Only the AT-III assay has more carefully specified inputs and outputs,spectrolyse heparin antifactor-Xa assay,,"PMID:19696660#Antifactor-Xa (anti-Xa) was determined using spectrolyse heparin (Xa) (Trinity Biotech plc, Bray, County Wicklow, Ireland).",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000808,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,spectrolyse heparin antifactor-Xa assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0002005,Methylation 27K BeadChip,Illumina Infinium Human Methylation 27K BeadChip,"A methylation BeadChip which is manufactured by the Illumina corporation. Built upon BeadChip tehcnology, the array interrogates ~ 27,000 CpG sites per sample at single-nucleotide resolution.",false,,,http://purl.obolibrary.org/obo/OBI_0001870,,,,Illumina Infinium Human Methylation 27K BeadChip,,,,,,,,,,,,,,,"A methylation BeadChip which is manufactured by the Illumina corporation. Built upon BeadChip tehcnology, the array interrogates ~ 27,000 CpG sites per sample at single-nucleotide resolution.",http://res.illumina.com/documents/products/datasheets/datasheet_dna_methylation_analysis.pdf,,,,,,Methylation 27K BeadChip,,"Polidoro, Silvia, et al. ""Effects of bisphosphonate treatment on DNA methylation in osteonecrosis of the jaw."" Mutation Research/Genetic Toxicology and Environmental Mutagenesis 757.2 (2013): 104-113. PMID: 23892139",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002005,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Methylation 27K BeadChip,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"PERSON: Venkat Malladi, Chris Stoeckert, Jie Zheng, Alan Ruttenberg",,
http://purl.obolibrary.org/obo/OBI_0000830,obsolete_primary structure of sequence macromolecule,,"A quality inhering in a molecule that is completely defined by the linear sequence of a set of residues which are connected by directional, linear bonds|replaced by SO_0000001 region",true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,"these are not in great shape yet; need to clarify how what a 'sequence macromolecule is' and how it differes from molecules in general (directivity of certain bonds, linear connectivity along that type of bond etc.)",,"A quality inhering in a molecule that is completely defined by the linear sequence of a set of residues which are connected by directional, linear bonds",,,,,,These are all placeholders and should be replaced by SO terms|2010-06-28 Alan Ruttenberg. This term and its children to be replaced by sequence ontology terms once we figure out what the right terms are .,obsolete_primary structure of sequence macromolecule,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000228,,,,,,,,,,,,,,,,,,OBI:0000830,,,,,,,,,,,,,,,,,,replaced by SO_0000001 region,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_primary structure of sequence macromolecule,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000705,Edman degradation,,A sequencing assay in which the amino acid sequence of input peptides or proteins is determined by iteratively cleaving of the amino-terminal (N-terminal) residue without disrupting the peptide bonds and identifying it by e.g. chromatography or electropheresis.,false,,,http://purl.obolibrary.org/obo/OBI_0600047,,,,,,,,,,,,,,,,,,,A sequencing assay in which the amino acid sequence of input peptides or proteins is determined by iteratively cleaving of the amino-terminal (N-terminal) residue without disrupting the peptide bonds and identifying it by e.g. chromatography or electropheresis.,IEDB,,,,,,Edman degradation,,Determination of the amino acid sequence of a peptide eluted from HLA-DRB1*04:01 to be VYPEVTVYPAKT.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000705,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Edman degradation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001540,obsolete T cell recognition of eluted MHC ligand assay,T cell recognition,An assay that identifies an MHC ligand using a T cell response assay as a readout,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,An assay that identifies an MHC ligand using a T cell response assay as a readout,IEDB,,,,,,obsolete T cell recognition of eluted MHC ligand assay,,Using proliferation of a T cell line specific for SIINFEKL in response to material eluted from a cell as evidence that SIINFEKL was presented by MHC on that cell. ,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000227,,,,,,,,,,,,,,,,,,OBI:0001540,,,,,,,,,,,,,,,,,,,,,,,,T cell recognition,,,,,,,,,,,,,,,,,,,,,,obsolete T cell recognition of eluted MHC ligand assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Randi Vita, Bjoern Peters",http://purl.obolibrary.org/obo/OBI_0001469,
http://purl.obolibrary.org/obo/OBI_0000652,material combination,,is a material processing with the objective to combine two or more material entities as input into a single material entity as output.,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,,,,,,,,,,,,,,,,,,is a material processing with the objective to combine two or more material entities as input into a single material entity as output.,bp,,,,,"created at workshop as parent class for 'adding material into target', which is asymmetric, while combination encompasses all addition processes.",material combination,,Mixing two fluids. Adding salt into water. Injecting a mouse with PBS.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000040,http://purl.obolibrary.org/obo/BFO_0000040,,,OBI:0000652,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,material combination,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,bp,,
http://purl.obolibrary.org/obo/OBI_0001795,ELISPOT assay measuring epitope specific IP-10 production by T cells,CXCL10/IP-10 release|ELISPOT,An assay of epitope specific IP-10 production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001308,,,,,,,,,,,,,,,,,,,An assay of epitope specific IP-10 production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific IP-10 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001795,,,,,,,,,,,,,,,,,,,,,,,,CXCL10/IP-10 release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific IP-10 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001755,selection criterion,selection rule,A directive information entity which defines and states a principle of standard by which selection process may take place.,false,,,http://purl.obolibrary.org/obo/IAO_0000033,,,,selection rule,,,,,,,,,,,,,,,A directive information entity which defines and states a principle of standard by which selection process may take place.,OBI discussion summarized under the following tracker item : http://sourceforge.net/p/obi/obi-terms/678/,,,,,,selection criterion,,rats should be aged between 6 and 8 weeks and weight between 180-250grams,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001755,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,selection criterion,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/IAO_0000055,rule,,"a rule is an executable which guides, defines, restricts actions",false,,,http://purl.obolibrary.org/obo/IAO_0000001,,,,,,,,,,,,,,,,,,,"a rule is an executable which guides, defines, restricts actions",OBI_0500021|PRS,,,,,MSI,rule,,example to be added,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000055,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,rule,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PRS,,
http://purl.obolibrary.org/obo/OBI_1110024,environmental exposure to infectious agent,,Is a process in which an infectious agent is in direct contact with a potential host organism in its habitat. This is preceded by proximity to the infectious agent,false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,Is a process in which an infectious agent is in direct contact with a potential host organism in its habitat. This is preceded by proximity to the infectious agent,IEDB,,,,,,environmental exposure to infectious agent,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110024,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,environmental exposure to infectious agent,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001740,quenching assay measuring the off rate [koff] of a B cell epitope:antibody complex,off rate|quenching|1/s,A B cell epitope binding off rate measurement (koff) determination assay that uses an antibody binding detection by fluorescence quenching assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001499|http://purl.obolibrary.org/obo/OBI_0001723,,,,,,,,,,,,,,,,,,,A B cell epitope binding off rate measurement (koff) determination assay that uses an antibody binding detection by fluorescence quenching assay.,IEDB,,,,,,quenching assay measuring the off rate [koff] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001740,,,,,,,,,,,,,,,,,,,,,,,,off rate|quenching|1/s,,,,,,,,,,,,,,,,,,,,,,quenching assay measuring the off rate [koff] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000728,rodent care,,rodent care  is the process by which rodents are being provided with a controlled living environment while kept in captivity for the purpose of research.,false,,,http://purl.obolibrary.org/obo/OBI_0000708,,,,,,,,,,,,,,,,,,,rodent care  is the process by which rodents are being provided with a controlled living environment while kept in captivity for the purpose of research.,PPPB branch,,,,,,rodent care,,keeping animal,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000694,,,,,,,,,,,,http://purl.obolibrary.org/obo/NCBITaxon_9989,http://purl.obolibrary.org/obo/NCBITaxon_9989,,,OBI:0000728,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,rodent care,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PPPB branch,,
http://purl.obolibrary.org/obo/OBI_0002052,in vivo assay measuring B cell epitope specific protection from tumor challenge,tumor burden after challenge|in vivo assay,A B cell epitope in vivo intervention experiment that uses a protection from challenge in vivo intervention experiment based on tumor burden.,false,,,http://purl.obolibrary.org/obo/OBI_0001710,,,,,,,,,,,,,,,,,,,A B cell epitope in vivo intervention experiment that uses a protection from challenge in vivo intervention experiment based on tumor burden.,IEDB,,,,,,in vivo assay measuring B cell epitope specific protection from tumor challenge,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001982,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001906,,,,OBI:0002052,,,,,,,,,,,,,,,,,,,,,,,,tumor burden after challenge|in vivo assay,,,,,,,,,,,,,,,,,,,,,,in vivo assay measuring B cell epitope specific protection from tumor challenge,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/GO_0044808,Oncostatin M production,,"The appearance of Oncostatin M due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of Oncostatin M due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,Oncostatin M production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0044808,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,Oncostatin M production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0044809,chemokine (C-C motif) ligand 17 production,,"The appearance of chemokine (C-C motif) ligand 17 (CCL17) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0032602,,,,,,,,,,,,,,,,,,,"The appearance of chemokine (C-C motif) ligand 17 (CCL17) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,chemokine (C-C motif) ligand 17 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0044809,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,chemokine (C-C motif) ligand 17 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0044807,macrophage migration inhibitory factor production,,"The appearance of macrophage migration inhibitory factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of macrophage migration inhibitory factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,macrophage migration inhibitory factor production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0044807,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,macrophage migration inhibitory factor production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/CL_0000066,epithelial cell,,A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina.,false,,,http://purl.obolibrary.org/obo/CL_0000000,,,,,,,,,,,,,,,,,,,A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina.,,,,,,,epithelial cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CL:0000066,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/cl.owl,,,,,,,,,,,,,,,,,,,epithelial cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000538,in-line filter,,"A solvent filter that sits between the pump and the injection valve that prevents dust particles, general debris and, to some extent, bacteria from entering the chromatography system. Contaminants can interfere with the low-pressure gradient former or the pump and particles entering valves may interfere with the proper function. The result could cause an increased baseline noise, non-repeatable gradient forming, unreliable flow rate or other interferences. Solvent in-line filters are low-pressure filters and will allow a high flow rate due to a large surface area and large porosity.",false,,,http://purl.obolibrary.org/obo/OBI_0000592,,,,,,,,,,,,,,,,,,,"A solvent filter that sits between the pump and the injection valve that prevents dust particles, general debris and, to some extent, bacteria from entering the chromatography system. Contaminants can interfere with the low-pressure gradient former or the pump and particles entering valves may interfere with the proper function. The result could cause an increased baseline noise, non-repeatable gradient forming, unreliable flow rate or other interferences. Solvent in-line filters are low-pressure filters and will allow a high flow rate due to a large surface area and large porosity.",WEB:<http://www.appliedporous.com/frits-chromatography.htm>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01123,,,,,,in-line filter,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000538,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,in-line filter,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001536,equilibrium dissociation constant (KD),,A binding constant defined as the ratio of kon over koff (on-rate of binding divided by off-rate),false,,,http://purl.obolibrary.org/obo/OBI_0001144,,,,,,,,,,,,,,,,,,,A binding constant defined as the ratio of kon over koff (on-rate of binding divided by off-rate),IEDB,,,,,,equilibrium dissociation constant (KD),,KD = 32 nM is the equilibrium dissociation rate found for peptide SIINFEKL binding to H-2 Kb,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,http://purl.obolibrary.org/obo/UO_0000051,,,,,,,,,,,,,,,,,,,,,OBI:0001536,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,equilibrium dissociation constant (KD),,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Bjoern Peters, Randi Vita",,
http://purl.obolibrary.org/obo/OBI_0001257,epitope specific interleukin-1 alpha production by T cells,,A process of interleukin-1 alpha production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/OBI_0001193|http://purl.obolibrary.org/obo/GO_0032610,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of interleukin-1 alpha production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific interleukin-1 alpha production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001257,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific interleukin-1 alpha production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001584,purified MHC direct binding assay measuring binding of a MHC:ligand complex using phage display,qualitative binding|purified MHC/direct/phage display,A purified MHC binding assay that uses a phage display binding assay to measure direct ligand binding.,false,,,http://purl.obolibrary.org/obo/OBI_0001555,,,,,,,,,,,,,,,,,,,A purified MHC binding assay that uses a phage display binding assay to measure direct ligand binding.,IEDB,,,,,,purified MHC direct binding assay measuring binding of a MHC:ligand complex using phage display,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001476,,,,,,,,,,,,,,,,OBI:0001584,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|purified MHC/direct/phage display,,,,,,,,,,,,,,,,,,,,,,purified MHC direct binding assay measuring binding of a MHC:ligand complex using phage display,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/PATO_0001161,diluted,,A concentration which relatively low.,false,,,http://purl.obolibrary.org/obo/PATO_0001238,,,,,,,,,,,,,,,,,,,A concentration which relatively low.,,,,,,,diluted,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001161,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,diluted,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0001167,damaged,,"A structural quality inhering in a bearer by virtue of the bearer being harmed or injured or spoiled, such that its functionality is impaired.",false,,,http://purl.obolibrary.org/obo/PATO_0001237,,,,,,,,,,,,,,,,,,,"A structural quality inhering in a bearer by virtue of the bearer being harmed or injured or spoiled, such that its functionality is impaired.",,,,,,,damaged,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001167,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,damaged,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001593,competitive inhibition of binding assay,,A binding assay that detects the inhibition of binding between 2 material entities known to form a complex by the addition of a third material entity of interest. Inhibition of binding between the 2 materials reflects binding by the third material.,false,,,http://purl.obolibrary.org/obo/OBI_0001146,,,,,,,,,,,,,,,,,,,A binding assay that detects the inhibition of binding between 2 material entities known to form a complex by the addition of a third material entity of interest. Inhibition of binding between the 2 materials reflects binding by the third material.,IEDB,,,,,,competitive inhibition of binding assay,,"Detecting the inhibition of binding of a fluorescently labeled antibody to its known protein ligand bound to the bottom of an ELISA plate, by incubating the antibody in the presence of a peptide of interest, adding it to the plate, washing the plate, and detecing fluorescence which is a proxy for the presence of the bound antibody. Reduction in binding due to the presence of the peptide indicates that the antibody binds the peptide. ",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001593,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,competitive inhibition of binding assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001770,intracellular cytokine staining assay measuring epitope specific vascular endothelial growth factor production by T cells,VEGF release|ICS,An assay of epitope specific vascular endothelial growth factor production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001570,,,,,,,,,,,,,,,,,,,An assay of epitope specific vascular endothelial growth factor production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific vascular endothelial growth factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001770,,,,,,,,,,,,,,,,,,,,,,,,VEGF release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific vascular endothelial growth factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001121,gel electrophoresis system,electrophoresis system,A device that moves charged particles through a medium by using an electric field induced by electrodes.,false,,,http://purl.obolibrary.org/obo/OBI_0001053,,,,electrophoresis system,,,,,,,,,,,,,,,A device that moves charged particles through a medium by using an electric field induced by electrodes.,http://en.wikipedia.org/wiki/Category:Electrophoresis,,,,,,gel electrophoresis system,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001121,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,gel electrophoresis system,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001394,epitope specific cytotoxic T cell degranulation,,A process of cytotoxic T cell degranulation resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0043316,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of cytotoxic T cell degranulation resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific cytotoxic T cell degranulation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001394,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific cytotoxic T cell degranulation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/CLO_0000018,mortal cell line cell,,A cell line cell that is capable of replicating a limited number of times in culture before undergoing senescence.,false,,,http://purl.obolibrary.org/obo/CLO_0000001,,,,,,,,,,,,,,,,,,,A cell line cell that is capable of replicating a limited number of times in culture before undergoing senescence.,,,,,,,mortal cell line cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CLO:0000018,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/clo.owl,,,,,,,,,,,,,,,,,,,mortal cell line cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_1110122,pathologic process,,"abnormal, harmful processes caused by or associated with a disease",false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,"abnormal, harmful processes caused by or associated with a disease",IEDB,,,,,,pathologic process,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,pathologic process,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0600010,material acquisition,material procurement,An acquisition in which possession of a material entity is gained.,false,,,http://purl.obolibrary.org/obo/OBI_0600008,,,,material procurement,,,,,,,,,,,,,,,An acquisition in which possession of a material entity is gained.,IEDB,,,,,"This excludes processes that create or change materials, such as material transformations.|The assumption is that the object already exists in its current state, e.g, an available mouse strain purchased from the Jackson Lab, this is the differentia from specimen creation",material acquisition,,Acquiring 50 C57BL/6 mice bred in the animal facility of the institute as a service to investigators. Purchasing 1 mg of peptides synthesized by Mimotopes at 80% purity. Getting a gift of purified CD4+ specific antibodies presented by Stephen Schoenberger at LIAI.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000040,,,OBI:0600010,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,material acquisition,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Bjoern Peters, Alan Ruttenberg, Helen Parkinson",,
http://purl.obolibrary.org/obo/OBI_1110195,epitope specific IL-18 release by T cells,,A biological process where T cells produce IL-18 resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0032621|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,,,A biological process where T cells produce IL-18 resulting from the recognition of a T cell epitope.,IEDB,,,,,,epitope specific IL-18 release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110195,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific IL-18 release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001005,RNASE CL3 structure mapping assay,single nucleotide resolution mapping assay using RNAse CL3,a single-nucleotide-resolution ribonucleic acid structure mapping assay which uses RNAse CL3 as reagent and enzymatic probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,false,,,http://purl.obolibrary.org/obo/OBI_0001014,,http://purl.obolibrary.org/obo/OBI_0000441,,single nucleotide resolution mapping assay using RNAse CL3,,,,,,,,,,,,,,,a single-nucleotide-resolution ribonucleic acid structure mapping assay which uses RNAse CL3 as reagent and enzymatic probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,RNA ontology,,,,,,RNASE CL3 structure mapping assay,,PMID:16453415,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_33697,,,,OBI:0001005,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,RNASE CL3 structure mapping assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0600063,vector mediated expression,,vector mediated expression sis the generation of copies of biomaterial by in a cell_culture modified for this purpose by insertion of an expression vector,false,,,http://purl.obolibrary.org/obo/OBI_0600064,,,,,,,,,,,,,,,,,,,vector mediated expression sis the generation of copies of biomaterial by in a cell_culture modified for this purpose by insertion of an expression vector,OBI branch derived,,,,,needs defined relationship to cell culture,vector mediated expression,,"Construction of pRSS1327 expression vector by molecular cloning of a 1327-bp cDNA, which includes sequences of the entire coding region for RSS, into pBluescript. Expression in Escherichia coli of a functional, full-length RSS was confirmed by immunoblot analysis and enzymatic activity.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600063,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,vector mediated expression,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0000054,ratio of collected to emitted light,,A measurement datum measuring the amount of light collected s compared to the total amount of emitted light in the detector component of a flow cytometer instrument. The datum has a qualitative role,false,,,http://purl.obolibrary.org/obo/IAO_0000109,,,,,,,,,,,,,,,,,,,A measurement datum measuring the amount of light collected s compared to the total amount of emitted light in the detector component of a flow cytometer instrument. The datum has a qualitative role,Submitted by the Flow Cytometry community in DigitalEntity-FlowCytometry-2007-03-30.txt,,,,,,ratio of collected to emitted light,,10%,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000054,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ratio of collected to emitted light,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Chris Stoeckert|person:Kevin Clancy,,
http://purl.obolibrary.org/obo/OBI_0200162,tail probability for the proportion of false positives correction method,TPPFP correction method,"A TPPFP correction method is a MTP that controls the probability that the proportion of false positives among all rejected hypotheses is no greater than a constant q, where q is between 0 and 1.",false,,,http://purl.obolibrary.org/obo/OBI_0200089,,http://purl.obolibrary.org/obo/OBI_0000791,,TPPFP correction method,,,,,,,,,,,,,,,"A TPPFP correction method is a MTP that controls the probability that the proportion of false positives among all rejected hypotheses is no greater than a constant q, where q is between 0 and 1.","Dudoit, Sandrine and van der Laan, Mark J. (2008) Multiple Testing Procedures with Applications to Genomics.  New York: Springer , p. 20",,,,,,tail probability for the proportion of false positives correction method,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200162,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,tail probability for the proportion of false positives correction method,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Monnie McGee,,
http://purl.obolibrary.org/obo/OBI_0001422,organism part comparison design,,"A study design that compares tissues, regions, organs within or between organisms",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A study design that compares tissues, regions, organs within or between organisms",MO_953 organism_part_comparison_design,,,,,,organism part comparison design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000268,,,,,,,,,,,,,,,,OBI:0001422,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,organism part comparison design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0002071,in vitro assay measuring epitope specific proliferation of T cells,proliferation|in vitro assay,A T cell epitope specific proliferation assay that is performed on cells in vitro.,false,,,http://purl.obolibrary.org/obo/OBI_1110131,,,,,,,,,,,,,,,,,,,A T cell epitope specific proliferation assay that is performed on cells in vitro.,IEDB,,,,,,in vitro assay measuring epitope specific proliferation of T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002071,,,,,,,,,,,,,,,,,,,,,,,,proliferation|in vitro assay,,,,,,,,,,,,,,,,,,,,,,in vitro assay measuring epitope specific proliferation of T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_1110084,effector T cell function,,The function inhering in a T cell that is realized in an immune response that results from the T cell receptor binding to the MHC:epitope complex.,false,,,http://purl.obolibrary.org/obo/OBI_1110016,,,,,,,,,,,,,,,,,,,The function inhering in a T cell that is realized in an immune response that results from the T cell receptor binding to the MHC:epitope complex.,IEDB,,,,,,effector T cell function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110084,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CL_0000084,,,,,,,,,,,,,,,,,effector T cell function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000067,evaluant role,,a role that inheres in a material entity that is realized in an assay in which data is generated about the bearer of the evaluant role,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,"Feb 10, 2009.  changes after discussion at OBI Consortium Workshop Feb 2-6, 2009.  accepted as core term.",,a role that inheres in a material entity that is realized in an assay in which data is generated about the bearer of the evaluant role,OBI,,,,,"examples of features that could be described in an evaluant: quality.... e.g. ""contains 10 pg/ml IL2"", or ""no glucose detected"")|Role call - 17nov-08: JF and MC think an evaluant role is always specified input of a process. Even in the case where we have an assay taking blood as evaluant and outputting blood, the blood is not the specified output at the end of the assay (the concentration of glucose in the blood is)",evaluant role,,"When a specimen of blood is assayed for glucose concentration, the blood has the evaluant role. When measuring the mass of a mouse, the evaluant is the mouse. When measuring the time of DNA replication, the evaluant is the DNA. When measuring the intensity of light on a surface, the evaluant is the light source.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000067,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,evaluant role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP:  Role Branch,,
http://purl.obolibrary.org/obo/IAO_0000008,obsolete_artifact,,,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_artifact,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,IAO:0000008,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_artifact,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001503,MHC protein complex binding to ligand,,The process in which a ligand binds to an MHC molecule to form a stable complex ,false,,,http://purl.obolibrary.org/obo/OBI_0001588,,,,,,,,,,,,,,,,,,,The process in which a ligand binds to an MHC molecule to form a stable complex ,IEDB,,,,,6/13/11 BP: The disposition referenced is the one of the ligand to bind the molecule. This along with binding as a function / process needs to be figured out with GO which is inconsistent at this point. ,MHC protein complex binding to ligand,,The peptide SIINFEKL binding to an empty murine H-2 Kb molecule to form a complex. ,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001503,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,MHC protein complex binding to ligand,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters; Randi Vita,,
http://purl.obolibrary.org/obo/OBI_0200057,replicate analysis,,"A replicate analysis is a data transformation in which data from replicates are combined, e.g. through descriptive statistics calculations, and the results might be utilized for a variety of purposes, like assessing reproducibility, identifying outliers, normalizing, etc.",false,,,http://purl.obolibrary.org/obo/OBI_0200169,,http://purl.obolibrary.org/obo/OBI_0200167,,,,,,,,,,,,,,,,,"A replicate analysis is a data transformation in which data from replicates are combined, e.g. through descriptive statistics calculations, and the results might be utilized for a variety of purposes, like assessing reproducibility, identifying outliers, normalizing, etc.",PERSON: Helen Parkinson|PERSON:Elisabetta Manduchi,,,,,,replicate analysis,,Replicate analysis can be used in microarray analysis to identify and potentially exclude low quality data.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200057,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,replicate analysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Helen Parkinson|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0001669,far-Western blot,,"is a adaptation on the western blot assay to explore protein-protein interaction. The assay involves separating target proteins on an SDS-PAGE gel, blotting to a membrane, hybridization with a protein probe and visualization using a probe-directed antibody. ",false,,,http://purl.obolibrary.org/obo/OBI_0000070|http://purl.obolibrary.org/obo/OBI_0001146,,,,,,,,,,,,,,,,,,,"is a adaptation on the western blot assay to explore protein-protein interaction. The assay involves separating target proteins on an SDS-PAGE gel, blotting to a membrane, hybridization with a protein probe and visualization using a probe-directed antibody. ","adapted from ECO, PMID:18079728",,,,,,far-Western blot,,"Studying protein-protein interactions via blot overlay or Far Western blot.
Hall RA.
Methods Mol Biol. 2004;261:167-74. Review.
PMID: 15064457",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001669,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,far-Western blot,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra; Marcus Chibucos,,
http://purl.obolibrary.org/obo/OBI_0001525,PDB file,,"A 3d structural organization datum capturing the results of X-ray crystallography or NMR experiment that is formatted as specified by the Protein Databank (http://www.wwpdb.org/docs.html). A PDB file can describe the structure of multiple molecules, each of which has a different chain identifier assigned. ",false,,,http://purl.obolibrary.org/obo/OBI_0001155,,,,,,,,,,,,,,,,,,,"A 3d structural organization datum capturing the results of X-ray crystallography or NMR experiment that is formatted as specified by the Protein Databank (http://www.wwpdb.org/docs.html). A PDB file can describe the structure of multiple molecules, each of which has a different chain identifier assigned. ",,,,,,,PDB file,,"The file found in the pdb with the identifier 3pe4

http://www.pdb.org/pdb/download/downloadFile.do?fileFormat=pdb&compression=NO&structureId=3pe4",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001525,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PDB file,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Bjoern Peters, Dorjee Tamang, Jason Greenbaum",,
http://purl.obolibrary.org/obo/OBI_0001620,latitude coordinate measurement datum,latitude|Specimen Collection Location - Latitude,A measurement datum that is the measure of the latitude coordinate of a site.,false,,,http://purl.obolibrary.org/obo/IAO_0000109,,,,latitude,,,,,,,,,,,,,,,A measurement datum that is the measure of the latitude coordinate of a site.,NIAID GSCID-BRC metadata working group,,,,,,latitude coordinate measurement datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001620,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,latitude coordinate measurement datum,,,,,,Specimen Collection Location - Latitude,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001919,Carbon-copy chromosome conformation capture assay,5C|5C assay,An assay that is used to analyze the organization of chromosomes at the genome-wide scale.,false,,,http://purl.obolibrary.org/obo/OBI_0600047,,http://purl.obolibrary.org/obo/OBI_0001917,,5C|5C assay,,,,,,,,,,,,,,,An assay that is used to analyze the organization of chromosomes at the genome-wide scale.,"""Dostie et al. Chromosome Conformation Capture Carbon Copy (5C): a massively parallel solution for mapping interactions between genomic elements. Genome Res. 2006 October; 16(10):1299-309.[PMID:16954542]""",,,,,,Carbon-copy chromosome conformation capture assay,,van Berkum et al. Determining spatial chromatin organization of large genomic regions using 5C technology. Methods Mol Biol (2009) vol. 567 pp. 189-213 [PMID:19588094],,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000800|http://purl.obolibrary.org/obo/OBI_0001914|http://purl.obolibrary.org/obo/OBI_0000711|http://purl.obolibrary.org/obo/OBI_0600050|http://purl.obolibrary.org/obo/OBI_0000626,http://purl.obolibrary.org/obo/OBI_0400103,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001573,,,OBI:0001919,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Carbon-copy chromosome conformation capture assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0600012,environmental material collection process,,"environmental_material_collection is an acquisition where an object is taken from an environment and put into a storage container. Roles include, environment, thing collected, container, acquirer.",false,,,http://purl.obolibrary.org/obo/OBI_0000659,,http://purl.obolibrary.org/obo/OBI_0000684,,,,,,,,,,,,,,,the researcher is very interested in the location,,"environmental_material_collection is an acquisition where an object is taken from an environment and put into a storage container. Roles include, environment, thing collected, container, acquirer.",IEDB,,,,,"relabel the term and add axiom connecting to EnVO:'environmental material'
discussed on obi-dev call 9/28/2015, details see: https://sourceforge.net/p/obi/obi-terms/779/",environmental material collection process,,Taking 1 liter of surface ocean water from the San Diego Mission Bay Jetty. Capturing mice living in rural Arkansas,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ENVO_00010483,http://purl.obolibrary.org/obo/OBI_0100051,,,OBI:0600012,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,environmental material collection process,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Bjoern Peters, Alan Ruttenberg",,
http://purl.obolibrary.org/obo/OBI_0600023,non specific enzymatic cleavage,,a protocol application to digest the fraction of input material that is susceptible to that enzyme,false,,,http://purl.obolibrary.org/obo/OBI_0000231,,,,,,,,,,,,,,,,,,,a protocol application to digest the fraction of input material that is susceptible to that enzyme,OBI branch derived,,,,,,non specific enzymatic cleavage,,The use of agarase to digest an agar gel,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600023,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,non specific enzymatic cleavage,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Kevin Clancy,,
http://purl.obolibrary.org/obo/OBI_0000604,detector lamp,,"A lamp used in a chromatography detector that excites sample molecules at certain frequencies / emission wavelengths, e.g. Mercury Vapor Lamp (253.7 nm), Zinc Vapor Lamp (2123.9 nm and 307.6 nm), Cadmium Vapor Lamp (228.8, 326.1,340.3, and 346.6 nm). To obtain monochromatic light an appropriate light filter would be needed.",false,,,http://purl.obolibrary.org/obo/OBI_0000601,,,,,,,,,,,,,,,,,,,"A lamp used in a chromatography detector that excites sample molecules at certain frequencies / emission wavelengths, e.g. Mercury Vapor Lamp (253.7 nm), Zinc Vapor Lamp (2123.9 nm and 307.6 nm), Cadmium Vapor Lamp (228.8, 326.1,340.3, and 346.6 nm). To obtain monochromatic light an appropriate light filter would be needed.",WEB:<http://www.chromatography-online.org/HPLC/UV-Detectors/Fixed-Wavelength/rs23.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01119,,,,,,detector lamp,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000604,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,detector lamp,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_1110035,Jurkat cell line,,A cell line derived from human T cells.,false,,,http://purl.obolibrary.org/obo/CLO_0009828,,,,,,,,,,,,,,,,,,,A cell line derived from human T cells.,http://www.biotech.ist.unige.it/cldb/cl5296.html|IEDB,,,,,,Jurkat cell line,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110035,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jurkat cell line,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/IAO_0000064,algorithm,,A plan specification which describes the inputs and output of mathematical functions as well as workflow of execution for achieving an predefined objective. Algorithms are realized usually by means of implementation as computer programs for execution by automata.,false,,,http://purl.obolibrary.org/obo/IAO_0000104,,,,,,,,,,,,,,,,,,,A plan specification which describes the inputs and output of mathematical functions as well as workflow of execution for achieving an predefined objective. Algorithms are realized usually by means of implementation as computer programs for execution by automata.,"OBI_0000270|adapted from discussion on OBI list (Matthew Pocock, Christian Cocos, Alan Ruttenberg)",,,,,,algorithm,,PMID: 18378114.Genomics. 2008 Mar 28. LINKGEN: A new algorithm to process data in genetic linkage studies.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000064,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,algorithm,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0400045,fluid pressure regulator,,"Part of the fluidic subsystem. The fluid pressure regulator maintains constant pressure within the sheath and or sample lines by filling the lines with enough gas to push the fluid at the desired rate. The gas is usually air, and less frequently nitrogen. In the sheath line, the gas is pushed into the sheath tank. In the sample line the gas is pushed into the collection tube. Fluid pressure regulators maintain great enough pressure to push sample fluid out of the tube and sheath fluid out of the sheath tank.",false,,,http://purl.obolibrary.org/obo/OBI_0001034|http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,"Part of the fluidic subsystem. The fluid pressure regulator maintains constant pressure within the sheath and or sample lines by filling the lines with enough gas to push the fluid at the desired rate. The gas is usually air, and less frequently nitrogen. In the sheath line, the gas is pushed into the sheath tank. In the sample line the gas is pushed into the collection tube. Fluid pressure regulators maintain great enough pressure to push sample fluid out of the tube and sheath fluid out of the sheath tank.","Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253",,,,,,fluid pressure regulator,,LSR2 fluid pressure regulator,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000453|http://purl.obolibrary.org/obo/OBI_0000401,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400045,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,fluid pressure regulator,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: John Quinn,,
http://purl.obolibrary.org/obo/OBI_0000373,ionize process,,a physical process of converting an atom or molecule into an ion by adding or removing charged particles such as electrons or other ions. This excludes chemical processes of dissociation.,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,a physical process of converting an atom or molecule into an ion by adding or removing charged particles such as electrons or other ions. This excludes chemical processes of dissociation.,,,,,,2009-11-10. Tracker: http://en.wikipedia.org/wiki/Ionize,ionize process,,Electrospray ionization in mass spectrometry,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000002,,,,,,,,,,,,,,,OBI:0000373,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ionize process,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000385,,,,,,,,,,,,,,,,Person:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0600031,enzyme-linked immunospot assay,ELISPOT assay,A cytometry assay in which cells are cultured on a surface coated with a capture antibody binding a secretory material of interest which subsequently gets stained resulting in a spot for each cell producing the secretory material of interest.,false,,,http://purl.obolibrary.org/obo/OBI_0001977,,,,ELISPOT assay,,,,,,,,,,,,,,,A cytometry assay in which cells are cultured on a surface coated with a capture antibody binding a secretory material of interest which subsequently gets stained resulting in a spot for each cell producing the secretory material of interest.,IEDB,,,,,,enzyme-linked immunospot assay,,"Determination of the frequency of cells producing IFN-gamma in response to viral peptides by placing effector cells on a anti IFN-gamma coated plate, and adding antigen presenting cells pulsed with a peptide. After washing, the bound IFN-gamma is detected with a secondary antibody linked to a dye that visualizes as one spot per cell.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600031,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,enzyme-linked immunospot assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001707,immunoglobulin mediated histamine release,,The release of histamine by cells stimulated through their Fc receptors which are loaded with immunoglobulins. ,false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,The release of histamine by cells stimulated through their Fc receptors which are loaded with immunoglobulins. ,IEDB,,,,,"4/26/12, BP: We want to import this from GO, which currently only has IgE mediated histamine release. We have requested the term, but need to use this as a placeholder in the meanwhile. ",immunoglobulin mediated histamine release,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000423,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001707,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,immunoglobulin mediated histamine release,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Bjoern Peters, Randi Vita",,
http://purl.obolibrary.org/obo/OBI_0001166,validation by real time PCR design,,a study design in which the accuracy or the quality of the result of an assay is checked by comparing with real time PCR results,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,a study design in which the accuracy or the quality of the result of an assay is checked by comparing with real time PCR results,MO_434 real_time_PCR_quality_control,,,,,,validation by real time PCR design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001166,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,validation by real time PCR design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001495,biological activity assay measuring epitope specific T cell helper activity,helper response|biological activity,A T cell epitope dependent biological activity assay that detects the ability of epitope specific helper T cells to enhance either B cell or T cell adaptive immune response function.,false,,,http://purl.obolibrary.org/obo/OBI_0002055,,,,,,,,,,,,,,,,,,,A T cell epitope dependent biological activity assay that detects the ability of epitope specific helper T cells to enhance either B cell or T cell adaptive immune response function.,IEDB,,,,,,biological activity assay measuring epitope specific T cell helper activity,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001495,,,,,,,,,,,,,,,,,,,,,,,,helper response|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific T cell helper activity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0200171,partitioning data transformation,,A partitioning data transformation is a data transformation that has objective partitioning.,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,A partitioning data transformation is a data transformation that has objective partitioning.,PERSON: James Malone,,,,,,partitioning data transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200171,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,partitioning data transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/GO_0042605,peptide antigen binding,,Interacting selectively and non-covalently with an antigen peptide.,false,,,http://purl.obolibrary.org/obo/GO_0003823,,,,,,,,,,,,,,,,,,,Interacting selectively and non-covalently with an antigen peptide.,,,,,,,peptide antigen binding,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0042605,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,peptide antigen binding,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001695,biological activity assay measuring epitope specific immune complex formation,agglutination|biological activity,A B cell epitope specific activation of additional immune response in vitro assay that detects agglutination.,false,,,http://purl.obolibrary.org/obo/OBI_0001704,,,,,,,,,,,,,,,,,,,A B cell epitope specific activation of additional immune response in vitro assay that detects agglutination.,IEDB,,,,,,biological activity assay measuring epitope specific immune complex formation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001695,,,,,,,,,,,,,,,,,,,,,,,,agglutination|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific immune complex formation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001352,allele information,,a genetic alteration information that about one of two or more alternative forms of a gene or marker sequence and differing from other alleles at one or more mutational sites based on sequence. Polymorphisms are included in this definition.,false,,,http://purl.obolibrary.org/obo/OBI_0001364,,,,,,,,,,,,,,,,,,,a genetic alteration information that about one of two or more alternative forms of a gene or marker sequence and differing from other alleles at one or more mutational sites based on sequence. Polymorphisms are included in this definition.,MO_58 Allele,,,,,"discussed on San Diego OBI workshop, March 2011",allele information,,"genotype information 'C57BL/6J  Hnf1a+/-' in this case, Hnf1a+/- is the allele information",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001352,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,allele information,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0600009,exposure of material to environment,,a planned process in which an input material is exposed to a defined set of conditions in a controlled environment. The environment is a specified input.,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,"Alan says there will be problmes, e.g. with selection by survival",,a planned process in which an input material is exposed to a defined set of conditions in a controlled environment. The environment is a specified input.,IEDB,,,,,,exposure of material to environment,,Putting cells in a freezer at -80C.  Cy5-labeled DNA is irradiated with a laser to excite the fluorophore. Inducing a phase transition in a material by putting it in an environment with a specific temperature. Oxygen deprivation in a chamber.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600009,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,exposure of material to environment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_1110013,ELISPOT assay measuring epitope specific interleukin-2 production by T cells,IL-2 release|ELISPOT,An assay of epitope specific interleukin-2 production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001445,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-2 production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific interleukin-2 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110013,,,,,,,,,,,,,,,,,,,,,,,,IL-2 release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific interleukin-2 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0200144,subgraph out-degree calculation,,A network subgraph quality calculation in which an input data set describing subgraphs and relationship edges between subgraphs and other network objects is used to enumerate the number of unique relationships pointing out of an individual subgraph.,false,,,http://purl.obolibrary.org/obo/OBI_0200137,,,,,,,,,,,,,,,,,,,A network subgraph quality calculation in which an input data set describing subgraphs and relationship edges between subgraphs and other network objects is used to enumerate the number of unique relationships pointing out of an individual subgraph.,PERSON: Richard Scheuermann,,,,,,subgraph out-degree calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200144,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,subgraph out-degree calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Richard Scheuermann,,
http://purl.obolibrary.org/obo/OBI_0000232,hardware optimization objective,,Hardware_optimization is a hardware_testing_objective describing a study designed to identify the best hardware.,false,,,http://purl.obolibrary.org/obo/OBI_0000134,,,,,,,,,,,,,,,,,,,Hardware_optimization is a hardware_testing_objective describing a study designed to identify the best hardware.,,,,,,,hardware optimization objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000232,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,hardware optimization objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0001776,biological activity assay measuring epitope specific chemokine (C-X-C motif) ligand 12 production by T cells,CXCL12/SDF-1 release|biological activity,A T cell epitope specific cytokine production assay that detects chemokine (C-X-C motif) ligand 12 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects chemokine (C-X-C motif) ligand 12 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific chemokine (C-X-C motif) ligand 12 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001776,,,,,,,,,,,,,,,,,,,,,,,,CXCL12/SDF-1 release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific chemokine (C-X-C motif) ligand 12 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0002021,NextSeq 500,Illumina NextSeq 500,"A DNA sequencer which is a desktop sequencer ideal for smaller-scale studies manufactured by the Illumina corporation. It supports sequencing of single, long or short insert paired end clone libraries relying on sequencing by synthesis technology.",false,,,http://purl.obolibrary.org/obo/OBI_0400103,,,,Illumina NextSeq 500,,,,,,,,,,,,,,,"A DNA sequencer which is a desktop sequencer ideal for smaller-scale studies manufactured by the Illumina corporation. It supports sequencing of single, long or short insert paired end clone libraries relying on sequencing by synthesis technology.",http://systems.illumina.com/systems/nextseq-sequencer.html,,,,,,NextSeq 500,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002021,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NextSeq 500,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0600046,preparative chromatography,,the use of a biomaterial's preferential affinity for either the mobile phase or the stationary phase to separate it from other materials of differing affinity,false,,,http://purl.obolibrary.org/obo/OBI_0600014,,http://purl.obolibrary.org/obo/OBI_0000681,,,,,,,,,,,,,,,,,the use of a biomaterial's preferential affinity for either the mobile phase or the stationary phase to separate it from other materials of differing affinity,OBI branch derived,,,,,,preparative chromatography,,The use of gas chromatography in order separate out from an input sample of eggs a fraction that would be enriched for pesticides.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000048|http://purl.obolibrary.org/obo/OBI_0000038,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000318,,,OBI:0600046,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,preparative chromatography,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Kevin Clancy; Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001010,nucleic acid extract,,An extract that is the output of an extraction process in which nucleic acid molecules are isolated from a specimen.,false,,,http://purl.obolibrary.org/obo/OBI_0000953|http://purl.obolibrary.org/obo/OBI_0000423,,,,,,,,,,,,,,,,,,,An extract that is the output of an extraction process in which nucleic acid molecules are isolated from a specimen.,UPenn Group,,,,,,nucleic acid extract,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,http://purl.obolibrary.org/obo/CHEBI_33696,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001010,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,nucleic acid extract,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Jie Zheng,,
http://purl.obolibrary.org/obo/OBI_0000454,extracellular electrophysiology recording,,An extracellular electrophysiology recording is process where the recording location of the electrode is extracellular and data,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,http://purl.obolibrary.org/obo/OBI_0000441,,,,,,,,,,,,,,,,,An extracellular electrophysiology recording is process where the recording location of the electrode is extracellular and data,PERSON: Frank Gibson,,,,,,extracellular electrophysiology recording,,"The recording of a spike train in the caudate nucleus of a monkey where the electrodes are extra cellular, i.e. not in the neuron",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000454,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,extracellular electrophysiology recording,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Frank Gibson, Helen Parkinson",,
http://purl.obolibrary.org/obo/OBI_0001966,sequence library deconvolution,,is a data transformation which uses sequence alignment and  'multiplex identifier sequence' information to pull together all reads belonging to a given single sample following the sequencing of a multiplexed library which combining several samples in one sequencing event,false,,,http://purl.obolibrary.org/obo/OBI_0200187,,http://purl.obolibrary.org/obo/OBI_0200081,,,,,,,,,,,,,,,,,is a data transformation which uses sequence alignment and  'multiplex identifier sequence' information to pull together all reads belonging to a given single sample following the sequencing of a multiplexed library which combining several samples in one sequencing event,PRS for OBI,,,,,,sequence library deconvolution,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001966,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sequence library deconvolution,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0600024,maintaining cell culture,,a protocol application in which cells are kept alive in a defined environment outside of an organism.  part of cell_culturing,false,,,http://purl.obolibrary.org/obo/OBI_0000838,,http://purl.obolibrary.org/obo/OBI_0000806,,,,,,,,,,,,,,,,,a protocol application in which cells are kept alive in a defined environment outside of an organism.  part of cell_culturing,OBI branch derived,,,,,,maintaining cell culture,,"When harvesting blood from a human, isolating T cells, and then limited dilution cloning of the cells, the maintaining_cell_culture step comprises all steps after the initial dilution and plating of the cells into culture, e.g. placing the culture into an incubator, changing or adding media, and splitting a cell culture",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100060,http://purl.obolibrary.org/obo/OBI_0100060,,,OBI:0600024,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,maintaining cell culture,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0002082,reporter gene assay,reporter gene detection assay,An assay in which expression of a reporter gene is detected that was inserted under the control of a regulatory sequence of interest.,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,reporter gene detection assay,,,,,,,,,,,,,,,An assay in which expression of a reporter gene is detected that was inserted under the control of a regulatory sequence of interest.,"Paul D. Thomas, Yang Chai; FaceBase",,,,,tracker item: 781,reporter gene assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002082,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,reporter gene assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Chris Stoeckert, Paul D. Thomas",,
http://purl.obolibrary.org/obo/OBI_0001905,secondary cultured cell population,secondary cell culture sample,"A cultured cell population that is derived through one or more passages in culture.|The concept of a 'secondary cultured cell population' covers cell lines as well as cultured cell populations more immediately derived from a primary culture which have yet to achieve adequate genetic stability and compositional homogeneity to be considered a cell line. The extent of the collection of cells in a 'secondary cultured cell population' is restricted only in that all cell members must share a propagation history (ie be derived through a common lineage of passages from an initial culture).  Secondary cultured cell populations can be under active culture, stored in a quiescent state for future use, or applied experimentally.",false,,,http://purl.obolibrary.org/obo/OBI_0100060,,,,secondary cell culture sample,,,,,,,,,,,,,,,A cultured cell population that is derived through one or more passages in culture.,PERSON:Matthew Brush,,,,,"The term 'secondary cell culture' is generally used in biological texts/protocols to refer to any culture of cells following an initial passage.  We include it here because there are often a number of passages between a primary culture and the establishment of a stable, homogenous cell line.  Such cultures are considered to be 'secondary cultures' but not 'cell lines' during this intermediate passaging/selection period between their derivation from a 'primary cell culture' and derivation into a 'cell line', which is a more specific type of secondary culture.",secondary cultured cell population,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,http://purl.obolibrary.org/obo/OBI_0001866,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001905,,,,,,,,,,,,,,,,,,"The concept of a 'secondary cultured cell population' covers cell lines as well as cultured cell populations more immediately derived from a primary culture which have yet to achieve adequate genetic stability and compositional homogeneity to be considered a cell line. The extent of the collection of cells in a 'secondary cultured cell population' is restricted only in that all cell members must share a propagation history (ie be derived through a common lineage of passages from an initial culture).  Secondary cultured cell populations can be under active culture, stored in a quiescent state for future use, or applied experimentally.",,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0600037,,,secondary cultured cell population,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_1110087,donor,donor role,"A role which inheres in an organism or part thereof from which any part including cell, organ or tissue is removed with the intention that the donated part will be placed into another organism and/or cultured in vitro.",false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,donor role,,,,,,,,,,,,,Definition modified by HP to deal with the case where an organ may be removed for donation but is not transplanted as intended.,,"A role which inheres in an organism or part thereof from which any part including cell, organ or tissue is removed with the intention that the donated part will be placed into another organism and/or cultured in vitro.",IEDB,,,,,,donor,,A T cell line from a PPD(+) donor.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110087,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,donor,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001019,RNA ADA I RNA structure mapping assay,single nucleotide resolution mapping assay using RNA adenosine deaminase I,a single-nucleotide-resolution ribonucleic acid structure mapping assay which uses RNA adenosine deaminase I as reagent and enzymatic probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,false,,,http://purl.obolibrary.org/obo/OBI_0001014,,http://purl.obolibrary.org/obo/OBI_0000441,,single nucleotide resolution mapping assay using RNA adenosine deaminase I,,,,,,,,,,,,,,,a single-nucleotide-resolution ribonucleic acid structure mapping assay which uses RNA adenosine deaminase I as reagent and enzymatic probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,RNA ontology,,,,,,RNA ADA I RNA structure mapping assay,,PMID:7527340,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_33697,,,,OBI:0001019,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,RNA ADA I RNA structure mapping assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000064,positive reference substance role,positive reference substance,"a reference role in which the characteristics or responses elicited by the substance playing the reference substance role are used to establish a ""100%"" response",false,,,http://purl.obolibrary.org/obo/OBI_0000025,,,,positive reference substance,,,,,,,,,,,,,,,"a reference role in which the characteristics or responses elicited by the substance playing the reference substance role are used to establish a ""100%"" response",,,,,,,positive reference substance role,,MMS mutagen,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000064,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,positive reference substance role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0400008,flow cytometer analyzer,,"An analyser is a flow_cytometer that is used to measure properties of particles (whole cells, nuclei, chromosomes, diatoms, plankton, bacteria, viruses) by moving these particles through a detection chamber. An analyser is used to collect data for analysis.",false,,,http://purl.obolibrary.org/obo/OBI_0400044,,,,,,,,,,,,,,,,,,,"An analyser is a flow_cytometer that is used to measure properties of particles (whole cells, nuclei, chromosomes, diatoms, plankton, bacteria, viruses) by moving these particles through a detection chamber. An analyser is used to collect data for analysis.",http://www.flocyte.com/FRTP/Resources/flow_cytometry_glossary.htm,,,,,,flow cytometer analyzer,,"FACS Calibur, Luminex 100",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0400079|http://purl.obolibrary.org/obo/OBI_0400065|http://purl.obolibrary.org/obo/OBI_0400082|http://purl.obolibrary.org/obo/OBI_0400043,,,,,,,,,,,,,,,,OBI:0400008,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,flow cytometer analyzer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0000422,syringe,,a processed material which is used to introduce or draw fluids from a material entity. A syringe is made of a piston and body. the movement of the piston in the body determines the amount/volume of fluid to inject or draw,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,a processed material which is used to introduce or draw fluids from a material entity. A syringe is made of a piston and body. the movement of the piston in the body determines the amount/volume of fluid to inject or draw,OBI Instrument adapted from Wikipedia,,,,,,syringe,,Accuracy of oral liquid measuring devices: comparison of dosing cup and oral dosing syringe.Ann Pharmacother. 2008 Jan;42(1):46-52. Epub 2007 Dec 4. PMID: 18056832,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/OBI_0000383,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000422,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,syringe,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001794,detection of specific nucleic acids with complementary probes assay measuring epitope specific lymphotoxin A production by T cells,lymphotoxin A/TNFb release|RNA/DNA detection,An assay of epitope specific lymphotoxin A production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001327|http://purl.obolibrary.org/obo/OBI_0001788,,,,,,,,,,,,,,,,,,,An assay of epitope specific lymphotoxin A production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific lymphotoxin A production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001794,,,,,,,,,,,,,,,,,,,,,,,,lymphotoxin A/TNFb release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific lymphotoxin A production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000537,copy number variation profiling,CNV analysis,"copy number variation profiling is a process which aims to provide information about lost or amplified genomic regions of DNA by comparing genomic DNA originated from tissues from same or different individuals using specific techniques such as CGH, array CGH, SNP genotyping.",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,http://purl.obolibrary.org/obo/OBI_0000441,,CNV analysis,,,,,,,,,,,,,,,"copy number variation profiling is a process which aims to provide information about lost or amplified genomic regions of DNA by comparing genomic DNA originated from tissues from same or different individuals using specific techniques such as CGH, array CGH, SNP genotyping.",,,,,,,copy number variation profiling,,"Profiling of copy number variations (CNVs) in healthy individuals from three ethnic groups using a human genome 32 K BAC-clone-based array.
de Ståhl TD, Sandgren J, Piotrowski A, Nord H, Andersson R, Menzel U, Bogdan A, Thuresson AC, Poplawski A, von Tell D, Hansson CM, Elshafie AI, Elghazali G, Imreh S, Nordenskjöld M, Upadhyaya M, Komorowski J, Bruder CE, Dumanski JP.
Hum Mutat. 2008 Mar;29(3):398-408. PMID: 18058796",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000537,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,copy number variation profiling,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001033,perturbation device,,A perturbation device is a device which is designed to perform a perturb function,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A perturbation device is a device which is designed to perform a perturb function,PERSON: Helen Parkinson|OBI Vancouver workshop 2010,,,,,,perturbation device,,A homogenizer is a perturbation device.|,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001033,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,perturbation device,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0002033,translation-associated transcript leader sequencing,TATL-seq,An RNA-seq assay that combines TL-seq with polysome fractionation,false,,,http://purl.obolibrary.org/obo/OBI_0001271,,,,TATL-seq,,,,,,,,,,,,,,,An RNA-seq assay that combines TL-seq with polysome fractionation,pmid:23580730,,,,,Details see tracker: https://sourceforge.net/p/obi/obi-terms/725/,translation-associated transcript leader sequencing,,pmid:23580730,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002033,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,translation-associated transcript leader sequencing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Saccharomyces Genome Database (SGD),,,,,,,,"Janos Demeter, Chris Stoeckert",,
http://purl.obolibrary.org/obo/OBI_1110041,lymph node cell specimen,,"A cell specimen comprised of a mixed population of cells obtained by processing whole lymph node into individual cells, typically performed using a sieve. This population includes T cells, B cells, macrophages, and other cell types.",false,,,http://purl.obolibrary.org/obo/OBI_0001468|http://purl.obolibrary.org/obo/OBI_0000953,,,,,,,,,,,,,,,,,,,"A cell specimen comprised of a mixed population of cells obtained by processing whole lymph node into individual cells, typically performed using a sieve. This population includes T cells, B cells, macrophages, and other cell types.",IEDB,,,,,,lymph node cell specimen,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110041,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,lymph node cell specimen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001705,biological activity assay measuring epitope specific antigen inhibition of antibody activity,antibody activity inhibition|biological activity,A B cell epitope dependent biological activity determination assay that detects inhibition of the antibody's activity by the antigen.,false,,,http://purl.obolibrary.org/obo/OBI_0001706,,,,,,,,,,,,,,,,,,,A B cell epitope dependent biological activity determination assay that detects inhibition of the antibody's activity by the antigen.,IEDB,,,,,,biological activity assay measuring epitope specific antigen inhibition of antibody activity,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001705,,,,,,,,,,,,,,,,,,,,,,,,antibody activity inhibition|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific antigen inhibition of antibody activity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001261,ELISA measuring epitope specific interleukin-1 alpha production by T cells,IL-1a release|ELISA,An assay of epitope specific interleukin-1 alpha production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001388,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-1 alpha production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific interleukin-1 alpha production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001261,,,,,,,,,,,,,,,,,,,,,,,,IL-1a release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific interleukin-1 alpha production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001256,epitope specific lymphotoxin A production by T cells,,A process of lymphotoxin A production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/OBI_0001351|http://purl.obolibrary.org/obo/GO_0032641,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of lymphotoxin A production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific lymphotoxin A production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001256,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific lymphotoxin A production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/NCBITaxon_6239,Caenorhabditis elegans,nematode,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_1206794,,,,nematode,,,,,,,,,,,,,,,,,,,,,,Caenorhabditis elegans,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:6239,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Caenorhabditis elegans,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0500001,clinical study design,,"Plan for the precise procedure to be followed in a clinical trial, including planned and actual timing of events, choice of control group, method of allocating treatments, blinding methods; assigns a subject to pass through one or more epochs in the course of a trial. Specific design elements, e.g., crossover, parallel; dose-escalation [Modified from Pocock, Clinical Trials: A Practical Approach]",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"Plan for the precise procedure to be followed in a clinical trial, including planned and actual timing of events, choice of control group, method of allocating treatments, blinding methods; assigns a subject to pass through one or more epochs in the course of a trial. Specific design elements, e.g., crossover, parallel; dose-escalation [Modified from Pocock, Clinical Trials: A Practical Approach]",Clinical Research Glossary Version 4.0 CDICS glossary group,,,,,The definition needs to be extended to other things than simply patients,clinical study design,,PMID: 17655677.J Cardiovasc Electrophysiol. 2007 Aug;18(9):965-71.Biventricular versus right ventricular pacing in patients with AV block (BLOCK HF): clinical study design and rationale.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500001,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,clinical study design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0200121,standard deviation calculation,,A standard deviation calculation is a descriptive statistics calculation defined as the square root of the variance.  Also thought of as the average distance of each value to the mean.,false,,,http://purl.obolibrary.org/obo/OBI_0200184|http://purl.obolibrary.org/obo/OBI_0200086,,http://purl.obolibrary.org/obo/OBI_0200078|http://purl.obolibrary.org/obo/OBI_0200180,,,,,,,,,,,,,,,From Monnie's file comments - need to add spread calculation role but they doesn't exist yet - (editor note added by James Jan 2008),,A standard deviation calculation is a descriptive statistics calculation defined as the square root of the variance.  Also thought of as the average distance of each value to the mean.,PERSON: Monnie McGee,,,,,,standard deviation calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200121,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,standard deviation calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Monnie McGee,,
http://purl.obolibrary.org/obo/OBI_0400022,Cyan,,"A Cyan is a flow_cytometer_analyser manufactured by Dako Cytomation. It features include digital electronics, three lasers: 488 nm, 635 nm, and 405 nm, and filters and collectors for nine fluorescent parameters and two scatter parameters. The Cyan can be used for measuring the properties of individual cells.",false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,,,,,,,,,,,,,,,,"A Cyan is a flow_cytometer_analyser manufactured by Dako Cytomation. It features include digital electronics, three lasers: 488 nm, 635 nm, and 405 nm, and filters and collectors for nine fluorescent parameters and two scatter parameters. The Cyan can be used for measuring the properties of individual cells.",http://www.dakousa.com/prod_productrelatedinformation?url=gprod_cyan_index.htm,,,,,,Cyan,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400022,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Cyan,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0400024,CyFlow SL,,"a flow_cytometer_analyser manufactured by Partec. Its specs are: ultracompact and fully equipped mobile/portable instrument, dimensions [cm]: L 43 x H 16 x D 37, highest stability/robustness and highest precision, 5 optical parameters: FSC, SSC, FL-1, FL-2, FL-3, 20mW@488nm blue solid state laser , other laser light sources optional (UV, violet, green, red), WindowsTM XP FloMax (software for real time data acquisition, data display, and data evaluation), parallel 16 bit digital pulse processing Compact mobile Flow Cytometer for any kind of cell analysis and absolute volumetric counting. The CyFlow_SL allows to analyze forward and side scatter signals in combination with up to 3 fluorescence channels.",false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,,,,,,,,,,,,,,,,"a flow_cytometer_analyser manufactured by Partec. Its specs are: ultracompact and fully equipped mobile/portable instrument, dimensions [cm]: L 43 x H 16 x D 37, highest stability/robustness and highest precision, 5 optical parameters: FSC, SSC, FL-1, FL-2, FL-3, 20mW@488nm blue solid state laser , other laser light sources optional (UV, violet, green, red), WindowsTM XP FloMax (software for real time data acquisition, data display, and data evaluation), parallel 16 bit digital pulse processing Compact mobile Flow Cytometer for any kind of cell analysis and absolute volumetric counting. The CyFlow_SL allows to analyze forward and side scatter signals in combination with up to 3 fluorescence channels.",http://www.partec.de/products/cyflow.html,,,,,,CyFlow SL,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400024,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CyFlow SL,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0001210,cytometric bead array assay measuring epitope specific transforming growth factor-beta production by T cells,TGFb release|cytometric bead array,An assay of epitope specific transforming growth factor-beta production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001264,,,,,,,,,,,,,,,,,,,An assay of epitope specific transforming growth factor-beta production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific transforming growth factor-beta production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001210,,,,,,,,,,,,,,,,,,,,,,,,TGFb release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific transforming growth factor-beta production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0200044,complete linkage hierarchical clustering,,"an agglomerative hierarchical clustering which generates successive clusters based on a distance measure, where the distance between two clusters is calculated as the maximum distance between objects from the first cluster and objects from the second cluster.",false,,,http://purl.obolibrary.org/obo/OBI_0200154,,,,,,,,,,,,,,,,,,,"an agglomerative hierarchical clustering which generates successive clusters based on a distance measure, where the distance between two clusters is calculated as the maximum distance between objects from the first cluster and objects from the second cluster.",PERSON: Elisabetta Manduchi,,,,,,complete linkage hierarchical clustering,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200044,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,complete linkage hierarchical clustering,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/CHEBI_30682,ruthenium atom,,An iron group element atom that has formula Ru.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,An iron group element atom that has formula Ru.,,,,,,,ruthenium atom,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:30682,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,ruthenium atom,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000528,liquid chromatography valve,,"A sample valve that must be able to sustain pressures up to 10,000 p.s.i., although it is most likely to operate on a continuous basis, at pressures of 3,000 p.s.i. or less. The higher the operating pressure the tighter the valve seating surfaces must be forced together to eliminate any leak. It follows that any abrasive material, however fine, that passes into the valve can cause the valve seating to become scored each time it is rotated which will ultimately lead to leaks. This will cause the sample size to vary between samples and eventually affect the accuracy of the analysis. It follows that any solid material must be carefully removed from any sample before filling the valve. The sample volume of an internal loop valve is situated in the connecting slot of the valve rotor and can be used only for relatively small sample volumes. Internal sample loop valves provide samples with volumes ranging from 0.1 ml to about 0.5 ml. Valve operation is shown in figure 6. The left-hand side diagram shows the load position. The sample occupies the rotor slot and has been filled by passing the sample from an appropriate syringe through the rotor slot to waste. While loading the sample, the mobile phase supply is passed through the valve directly to the column. To place the sample onto the column, the valve is then rotated and the valve slot containing the sample is now placed between the solvent supply and the column. As a result, the sample is passed into the column by the flow of solvent.",false,,,http://purl.obolibrary.org/obo/OBI_0000048,,,,,,,,,,,,,,,,,chromatography device,,"A sample valve that must be able to sustain pressures up to 10,000 p.s.i., although it is most likely to operate on a continuous basis, at pressures of 3,000 p.s.i. or less. The higher the operating pressure the tighter the valve seating surfaces must be forced together to eliminate any leak. It follows that any abrasive material, however fine, that passes into the valve can cause the valve seating to become scored each time it is rotated which will ultimately lead to leaks. This will cause the sample size to vary between samples and eventually affect the accuracy of the analysis. It follows that any solid material must be carefully removed from any sample before filling the valve. The sample volume of an internal loop valve is situated in the connecting slot of the valve rotor and can be used only for relatively small sample volumes. Internal sample loop valves provide samples with volumes ranging from 0.1 ml to about 0.5 ml. Valve operation is shown in figure 6. The left-hand side diagram shows the load position. The sample occupies the rotor slot and has been filled by passing the sample from an appropriate syringe through the rotor slot to waste. While loading the sample, the mobile phase supply is passed through the valve directly to the column. To place the sample onto the column, the valve is then rotated and the valve slot containing the sample is now placed between the solvent supply and the column. As a result, the sample is passed into the column by the flow of solvent.",WEB:<http://www.chromatography-online.org/EC-Dispersion/HPLC-Sample-Valves/rs16.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01110,,,,,,liquid chromatography valve,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000528,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,liquid chromatography valve,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0200083,survival analysis objective,survival analysis,A data transformation objective which has the data transformation aims to model time to event data (where events are e.g. death and or disease recurrence); the purpose of survival analysis is to model the underlying distribution of event times and to assess the dependence of the event time on other explanatory variables,false,,,http://purl.obolibrary.org/obo/OBI_0200166,,,,survival analysis,,,,,,,,,,,,,,,A data transformation objective which has the data transformation aims to model time to event data (where events are e.g. death and or disease recurrence); the purpose of survival analysis is to model the underlying distribution of event times and to assess the dependence of the event time on other explanatory variables,http://en.wikipedia.org/wiki/Survival_analysis,,,,,,survival analysis objective,,Kaplan meier data transformation,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200083,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,survival analysis objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Tina Boussard|PERSON: James Malone,,
http://purl.obolibrary.org/obo/OBI_0001178,efficacy of epitope intervention experiment,efficacy of in vivo intervention,"An experiment that tests  if inducing an epitope specific immune response in an organism has an effect, such as the ability to prevent, treat or excarbate diseases in the organism. ",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,"An experiment that tests  if inducing an epitope specific immune response in an organism has an effect, such as the ability to prevent, treat or excarbate diseases in the organism. ",,,,,,,efficacy of epitope intervention experiment,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001192,,,,,,,,,,,,,,,,OBI:0001178,,,,,,,,,,,,,,,,,,,,,,,,efficacy of in vivo intervention,,,,,,,,,,,,,,,,,,,,,,efficacy of epitope intervention experiment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000822,single blind study execution,,A single blind study execution is defined as any study execution in which the subjects are not informed of which study arm they are part of during the portion of the trial when the subjects are being treated,false,,,http://purl.obolibrary.org/obo/OBI_0000826,,,,,,,,,,,,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,,A single blind study execution is defined as any study execution in which the subjects are not informed of which study arm they are part of during the portion of the trial when the subjects are being treated,http://clinicaltrials.gov/ct2/info/glossary#single,,,,,,single blind study execution,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000822,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,single blind study execution,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0001564,purified MHC competitive binding assay measuring equilibrium dissociation constant [KD] of a MHC:ligand complex approximated by IC50 using radioactivity detection,dissociation constant KD (~IC50)|purified MHC/competitive/radioactivity|nM,A purified MHC ligand binding equilibrium dissociation constant (KD) determination assay that uses radioactivity detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation and provides IC50 values determined under assay conditions where the IC50 approximates a KD value. ,false,,,http://purl.obolibrary.org/obo/OBI_0001989,,,,,,,,,,,,,,,,,,,A purified MHC ligand binding equilibrium dissociation constant (KD) determination assay that uses radioactivity detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation and provides IC50 values determined under assay conditions where the IC50 approximates a KD value. ,IEDB,,,,,,purified MHC competitive binding assay measuring equilibrium dissociation constant [KD] of a MHC:ligand complex approximated by IC50 using radioactivity detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000201,,,,,,,,,,,,,,,,OBI:0001564,,,,,,,,,,,,,,,,,,,,,,,,dissociation constant KD (~IC50)|purified MHC/competitive/radioactivity|nM,,,,,,,,,,,,,,,,,,,,,,purified MHC competitive binding assay measuring equilibrium dissociation constant [KD] of a MHC:ligand complex approximated by IC50 using radioactivity detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001985,microarray assay,,An analyte assay where binding of the analyte to immobilized matrix is measured.,false,,,http://purl.obolibrary.org/obo/OBI_0000443,,,,,,,,,,,,,,,,,,,An analyte assay where binding of the analyte to immobilized matrix is measured.,IEDB,,,,,,microarray assay,,Measuring if sera from an influenza A virus immunizedmouse binds to Hemagglutinin protein that is immobilized on a microarray.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001985,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,microarray assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/IAO_0000415,hypothesis textual entity,,A textual entity that expresses an assertion that is intended to be tested.,false,,,http://purl.obolibrary.org/obo/IAO_0000300,,,,,,,,,,,,,,,,,,,A textual entity that expresses an assertion that is intended to be tested.,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,hypothesis textual entity,,"that fucoidan has a small statistically significant effect on AT3 level but no useful clinical effect as in-vivo anticoagulant, a paraphrase of part of the last paragraph of the discussion section of the paper 'Pilot clinical study to evaluate the anticoagulant activity of fucoidan', by Lowenthal et. al.PMID:19696660",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000415,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,hypothesis textual entity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/GAZ_00000448,geographic location,,"A reference to a place on the Earth, by its name or by its geographical location.",false,,,http://purl.obolibrary.org/obo/BFO_0000029,,,,,,,,,,,,,,,,,,,"A reference to a place on the Earth, by its name or by its geographical location.",,,,,,,geographic location,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GAZ:00000448,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,geographic location,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001096,laser capture microdissection microscope,,A microscope that uses low-energy laser beams and special transfer film to lift single cells from a tissue.,false,,,http://purl.obolibrary.org/obo/OBI_0400169,,,,,,,,,,,,,,,,,,,A microscope that uses low-energy laser beams and special transfer film to lift single cells from a tissue.,http://www.answers.com/topic/laser-capture-microdissection-microscope-in-medicine,,,,,,laser capture microdissection microscope,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001096,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,laser capture microdissection microscope,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0400096,solid state laser,,"A solid-state laser is a laser that uses a lasing medium that is a solid, rather than a liquid such as dye lasers or a gas such as gas lasers. Semiconductor-based diode lasers are also in the solid state, but are generally considered separately from solid-state lasers. The first laser developed was an optical pumped ruby crystal solid state laser.",false,,,http://purl.obolibrary.org/obo/OBI_0400064,,,,,,,,,,,,,,,,,,,"A solid-state laser is a laser that uses a lasing medium that is a solid, rather than a liquid such as dye lasers or a gas such as gas lasers. Semiconductor-based diode lasers are also in the solid state, but are generally considered separately from solid-state lasers. The first laser developed was an optical pumped ruby crystal solid state laser.",http://en.wikipedia.org/wiki/Solid-state_laser,,,,,,solid state laser,,Solid State Heat Capacity Laser developed at DOE's Lawrence Livermore National Laboratory for the USA Army's Space and Missile Defense Command,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400096,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,solid state laser,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0302729,chemical solution,liquid chemical solution,"A material entity  that is made up of at least 2 scattered molecular aggregates, one playing the role of solvent and the other one playing the role of solute.",false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,liquid chemical solution,,,,,,,,,,,,,,,"A material entity  that is made up of at least 2 scattered molecular aggregates, one playing the role of solvent and the other one playing the role of solute.",GROUP: OBI Biomaterial Branch,,,,,,chemical solution,,PMID: 18289311.Anesth Analg. 2008 Apr;106(4):1078-86.Less impairment of hemostasis and reduced blood loss in pigs after resuscitation from hemorrhagic shock using the small-volume concept with hypertonic saline/hydroxyethyl starch as compared to administration of 4% gelatin or 6% hydroxyethyl starch solution.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302729,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,chemical solution,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters|PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001778,biological activity assay measuring epitope specific chemokine (C-X-C motif) ligand 16 production by T cells,CXCL16 release|biological activity,A T cell epitope specific cytokine production assay that detects chemokine (C-X-C motif) ligand 16 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects chemokine (C-X-C motif) ligand 16 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific chemokine (C-X-C motif) ligand 16 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001778,,,,,,,,,,,,,,,,,,,,,,,,CXCL16 release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific chemokine (C-X-C motif) ligand 16 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000161,crossover population role,crossover population,a role realized when a participant serves as reference to itself,false,,,http://purl.obolibrary.org/obo/OBI_0000220,,,,crossover population,,,,,,,,,,,,,,,a role realized when a participant serves as reference to itself,,,,,,,crossover population role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000161,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,crossover population role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0400094,sheath tank,,"Part of the fluidics system. The sheath tank is the vessel that holds the sheath fluid at a constant pressure, allowing for it to be pushed into the flow chamber at a constant rate. The sheath tank holds the pressurized sheath fluid.",false,,,http://purl.obolibrary.org/obo/OBI_0000967|http://purl.obolibrary.org/obo/OBI_0001034,,,,,,,,,,,,,,,,,,,"Part of the fluidics system. The sheath tank is the vessel that holds the sheath fluid at a constant pressure, allowing for it to be pushed into the flow chamber at a constant rate. The sheath tank holds the pressurized sheath fluid.","Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253",,,,,,sheath tank,,LSR2 sheath tank,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000370|http://purl.obolibrary.org/obo/OBI_0000401,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400094,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sheath tank,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/CL_0000542,lymphocyte,,"A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.",false,,,http://purl.obolibrary.org/obo/CL_0000842,,,,,,,,,,,,,,,,,,,"A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.",,,,,,,lymphocyte,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CL:0000542,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/cl.owl,,,,,,,,,,,,,,,,,,,lymphocyte,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/UO_0000105,frequency unit,,A unit which is a standard measure of the number of repetitive actions in a particular time.,false,,,http://purl.obolibrary.org/obo/IAO_0000003,,,,,,,,,,,,,,,,,,,A unit which is a standard measure of the number of repetitive actions in a particular time.,,,,,,,frequency unit,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UO:0000105,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uo.owl,,,,,,,,,,,,,,,,,,,frequency unit,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/UO_0000109,pressure unit,,A unit which is a standard measure of the force applied to a given area.,false,,,http://purl.obolibrary.org/obo/IAO_0000003,,,,,,,,,,,,,,,,,,,A unit which is a standard measure of the force applied to a given area.,,,,,,,pressure unit,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UO:0000109,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uo.owl,,,,,,,,,,,,,,,,,,,pressure unit,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000511,injector lubricant,,A lubricant used in liquid chromatography that eases sample injector penetration.,false,,,http://purl.obolibrary.org/obo/OBI_0000601,,,,,,,,,,,,,,,,,,,A lubricant used in liquid chromatography that eases sample injector penetration.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01118,,,,,,injector lubricant,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000511,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,injector lubricant,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001464,strain comparison design,,"A study design that assays differences between multiple strains, cultivars, serovars, isolates, lines from organisms of a single species.",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A study design that assays differences between multiple strains, cultivars, serovars, isolates, lines from organisms of a single species.",MO_462 strain_or_line_design,,,,,,strain comparison design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000268,,,,,,,,,,,,,,,,OBI:0001464,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,strain comparison design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000615,protein expression profiling,proteomic analysis,"a planned process which aims to provide information about protein expression and translation activity using protein extracts collected from a material entity using a range of techniques and instrument such as Mass spectrometers, Gel electrophoresis, Western Blots, Protein microarrays",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,http://purl.obolibrary.org/obo/OBI_0000441,,proteomic analysis,,,,,,,,,,,,,,,"a planned process which aims to provide information about protein expression and translation activity using protein extracts collected from a material entity using a range of techniques and instrument such as Mass spectrometers, Gel electrophoresis, Western Blots, Protein microarrays",OBI branch derived,,,,,,protein expression profiling,,"Protein Expression Profiling During Chick Retinal Maturation: A Proteomics-based approach.
Finnegan S, Robson JL, Wylie M, Healy A, Stitt AW, Curry WJ.
Proteome Sci. 2008 Dec 10;6(1):34.PMID: 19077203",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000615,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,protein expression profiling,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Phlippe Rocca-Serra,,
http://purl.obolibrary.org/obo/IAO_0000422,postal address,,"A textual entity that is used as directive to deliver something to a person, or organization",false,,,http://purl.obolibrary.org/obo/IAO_0000300,,,,,,,,,,,,,,,,,,,"A textual entity that is used as directive to deliver something to a person, or organization",,,,,,2010-05-24 Alan Ruttenberg. Use label for the string representation. See issue http://code.google.com/p/information-artifact-ontology/issues/detail?id=59,postal address,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000422,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/GAZ_00000448,,,,,,,,,,,,,,,,postal address,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_1110082,immunogen role,,any entity capable of eliciting an immune response when introduced to components of the immune system,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,,,any entity capable of eliciting an immune response when introduced to components of the immune system,IEDB,,,,,,immunogen role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110082,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,immunogen role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000390,thermostatic circulator,,A thermostatic circulator is a device which cools or heats a circulating liquid. It has the function to contain control the contained environment and transfer energy from or to the circulating liquid,false,,,http://purl.obolibrary.org/obo/OBI_0000967|http://purl.obolibrary.org/obo/OBI_0001034,,,,,,,,,,,,,,,,,,,A thermostatic circulator is a device which cools or heats a circulating liquid. It has the function to contain control the contained environment and transfer energy from or to the circulating liquid,sep:00098,,,,,,thermostatic circulator,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000370|http://purl.obolibrary.org/obo/OBI_0000401,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000390,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,thermostatic circulator,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Frank Gibson,,
http://purl.obolibrary.org/obo/OBI_0001049,chip spotting device,,"A device for dropping and immobilizing a solution of biomolecules, for example, nucleic acids such as probe DNA, mRNA, and peptide nucleic acid (PNA), and proteins on a DNA microarray surface to manufacture a DNA microarray.",false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,"A device for dropping and immobilizing a solution of biomolecules, for example, nucleic acids such as probe DNA, mRNA, and peptide nucleic acid (PNA), and proteins on a DNA microarray surface to manufacture a DNA microarray.",United States Patent 7416705,,,,,,chip spotting device,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000383,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001049,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,chip spotting device,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0302893,storage,,A maintenance process by which material entities that are not actively metabolizing are placed in well identified location and possibly under controlled environment in ad-hoc devices/structures in order to preserve and protect them from decay/alteration and maintain availability,false,,,http://purl.obolibrary.org/obo/OBI_0000838,,http://purl.obolibrary.org/obo/OBI_0000806,,,,,,,,,,,,,,,,,A maintenance process by which material entities that are not actively metabolizing are placed in well identified location and possibly under controlled environment in ad-hoc devices/structures in order to preserve and protect them from decay/alteration and maintain availability,OBI-Branch,,,,,,storage,,PMID: 18550121.Total Prostate Specific Antigen Stability Confirmed After Long-Term Storage of Serum at -80C. J Urol. 2008 Jun 10.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,OBI:0302893,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,storage,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001047,pH meter,,A device that is used to measure the pH (acidity or alkalinity) of a liquid.,false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,A device that is used to measure the pH (acidity or alkalinity) of a liquid.,http://en.wikipedia.org/wiki/PH_meter,,,,,,pH meter,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001047,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,pH meter,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0200132,node in-degree calculation,,A node quality calculation in which an input data set describing object nodes and directional relationship edges between object nodes is used to enumerate the number of unique relationships pointing into an individual object node.,false,,,http://purl.obolibrary.org/obo/OBI_0200129,,,,,,,,,,,,,,,,,,,A node quality calculation in which an input data set describing object nodes and directional relationship edges between object nodes is used to enumerate the number of unique relationships pointing into an individual object node.,PERSON: Richard Scheuermann,,,,,,node in-degree calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200132,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,node in-degree calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Richard Scheuermann,,
http://purl.obolibrary.org/obo/CHEBI_26710,sodium chloride,,An inorganic chloride salt having sodium(1+) as the counterion.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,An inorganic chloride salt having sodium(1+) as the counterion.,,,,,,,sodium chloride,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:26710,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,sodium chloride,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0500025,ethical standard compliance rule,,an ethical standard compliance rule is_a *compliance rule* which enable a  *ethical compliance process* to occur,false,,,http://purl.obolibrary.org/obo/OBI_0500024,,,,,,,,,,,,,,,,,,,an ethical standard compliance rule is_a *compliance rule* which enable a  *ethical compliance process* to occur,PRS,,,,,,ethical standard compliance rule,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500025,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ethical standard compliance rule,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PRS,,
http://purl.obolibrary.org/obo/OBI_0000210,analytical cytology data file,,A digital entity intended to capture data in analytical cytology domain.,false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,,,,,,,,,,,,,,,,A digital entity intended to capture data in analytical cytology domain.,group:Flow Cytometry community,,,,,,analytical cytology data file,,"FCS file, ACS file, foo.fcs, foo.asc",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000210,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,analytical cytology data file,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/IAO_0000018,obsolete_material_entity,,,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_material_entity,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000226,,,,,,,,,,,,,,,,,,IAO:0000018,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_material_entity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0500015,2x2 factorial design,,a factorial design which has 2 experimental factors (aka independent variables) and 2 factor levels per experimental factors,false,,,http://purl.obolibrary.org/obo/OBI_0500014,,,,,,,,,,,,,,,,,,,a factorial design which has 2 experimental factors (aka independent variables) and 2 factor levels per experimental factors,PMID: 17561240,,,,,,2x2 factorial design,,"PMID: 17561240-The present experiment evaluates the effects of intermittent exposure to a social stimulus on ethanol and water drinking in rats. Four groups of rats were arranged in a 2x2 factorial design with 2 levels of Social procedure (Intermittent Social vs Continuous Social) and 2 levels of sipper Liquid (Ethanol vs Water). Intermittent Social groups received 35 trials per session. Each trial consisted of the insertion of the sipper tube for 10 s followed by lifting of the guillotine door for 15 s. The guillotine door separated the experimental rat from the conspecific rat in the wire mesh cage during the 60 s inter-trial interval. The Continuous Social groups received similar procedures except that the guillotine door was raised during the entire duration of the session. For the Ethanol groups, the concentrations of ethanol in the sipper [3, 4, 6, 8, 10, 12, 14, and 16% (vol/vol)] increased across sessions, while the Water groups received 0% ethanol (water) in the sipper throughout the experiment. Both Social procedures induced more intake of ethanol than water. The Intermittent Social procedure induced more ethanol intake at the two highest ethanol concentration blocks (10-12% and 14-16%) than the Continuous Social procedure, but this effect was not observed with water. Effects of social stimulation on ethanol drinking are discussed.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500015,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2x2 factorial design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0200200,chi square test,,"The chi-square test is a data transformation with the objective of statistical hypothesis testing, in which the sampling distribution of the test statistic is a chi-square distribution when the null hypothesis is true, or any in which this is asymptotically true, meaning that the sampling distribution (if the null hypothesis is true) can be made to approximate a chi-square distribution as closely as desired by making the sample size large enough.",false,,,http://purl.obolibrary.org/obo/OBI_0000673,,http://purl.obolibrary.org/obo/OBI_0000675,,,,,,,,,,,,,,,,,"The chi-square test is a data transformation with the objective of statistical hypothesis testing, in which the sampling distribution of the test statistic is a chi-square distribution when the null hypothesis is true, or any in which this is asymptotically true, meaning that the sampling distribution (if the null hypothesis is true) can be made to approximate a chi-square distribution as closely as desired by making the sample size large enough.",,,,,,,chi square test,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200200,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,chi square test,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Tina Boussard|PERSON: James Malone,,
http://purl.obolibrary.org/obo/OBI_0000475,Bruker AutoClean system,,"NMR tubes are often used once and discarded, creating needless waste. With the Bruker BioSpin Autoclean system you can now recycle 5mm, 3mm, or 5mm/3mm step-down (Wilmad 520-1B) NMR tubes. AutoClean NMR Tube Washing System is a simple way to recoup the substantial investment your organization makes in quality NMR tubes, and cut back on needless waste material.",false,,,http://purl.obolibrary.org/obo/OBI_0000498,,,,,,,,,,,,,,,,,,,"NMR tubes are often used once and discarded, creating needless waste. With the Bruker BioSpin Autoclean system you can now recycle 5mm, 3mm, or 5mm/3mm step-down (Wilmad 520-1B) NMR tubes. AutoClean NMR Tube Washing System is a simple way to recoup the substantial investment your organization makes in quality NMR tubes, and cut back on needless waste material.",WEB:<http://www.used-line.com/c5983250s10028-Bruker_Biospin_NMR_Autoclean_Nuclear_Magnetic_Resonance_Organic_Solvents.htm>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400205,,,,,"washing system/NMR tube washing system, XPS: device has function washing",Bruker AutoClean system,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000475,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker AutoClean system,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001748,ELISPOT assay measuring epitope specific interferon-beta production by T cells,IFNb release|ELISPOT,An assay of epitope specific interferon-beta production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001390,,,,,,,,,,,,,,,,,,,An assay of epitope specific interferon-beta production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific interferon-beta production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001748,,,,,,,,,,,,,,,,,,,,,,,,IFNb release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific interferon-beta production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001972,Ion 318 Chip v2,Ion PGM 318 Chip v2|Ion PGM 318 Chip|Ion 318 Chip,"An ion semiconductor chip manufactured by Life Technologies which detects polymerase-driven base incorporation to translate into digital form. The 318 chip is compatible with the Ion Torrent PGM and has a run time of:

4.4 hours for 200 bp reads with an output of 60 Mb-1 Gb,
7.3 hours for 400 bp reads with an output of 1.2 Gb-2 Gb.",false,,,http://purl.obolibrary.org/obo/OBI_0001973,,,,Ion PGM 318 Chip v2|Ion PGM 318 Chip|Ion 318 Chip,,,,,,,,,,,,,,,"An ion semiconductor chip manufactured by Life Technologies which detects polymerase-driven base incorporation to translate into digital form. The 318 chip is compatible with the Ion Torrent PGM and has a run time of:

4.4 hours for 200 bp reads with an output of 60 Mb-1 Gb,
7.3 hours for 400 bp reads with an output of 1.2 Gb-2 Gb.",http://www.lifetechnologies.com/us/en/home/life-science/sequencing/next-generation-sequencing/ion-torrent-next-generation-sequencing-workflow/ion-torrent-next-generation-sequencing-run-sequence/ion-pgm-ion-proton-system-chips.html,,,,,"Issue Tracker #775
https://sourceforge.net/p/obi/obi-terms/775/",Ion 318 Chip v2,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001972,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Ion 318 Chip v2,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Sagar Jain,,
http://purl.obolibrary.org/obo/OBI_0400025,CyFlow SL3,,"A CyFlow_Sl3 is a flow_cytometer_analyser manufactured by Partec. Its specs are: ultracompact and fully equipped mobile/portable instrument, dimensions [cm]: L 43 x H 16 x D 37 , highest stability/robustness and highest precision, 5 optical parameters: FSC, SSC, FL-1, FL-2, FL-3, 20mW@488nm blue solid state laser, other laser light sources optional (UV, violet, green, red), WindowsTM XP FloMax (software for real time data acquisition, data display, and data evaluation), parallel 16 bit digital pulse processing. The CyFlow SL3 is a compact and dedicated portable Flow Cytometer for accurate and affordable cell analysis and true volumetric absolute counting in HIV Monitoring and AIDS patient follow-up by precise and direct CD4 and CD4% measurement.",false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,,,,,,,,,,,,,,,,"A CyFlow_Sl3 is a flow_cytometer_analyser manufactured by Partec. Its specs are: ultracompact and fully equipped mobile/portable instrument, dimensions [cm]: L 43 x H 16 x D 37 , highest stability/robustness and highest precision, 5 optical parameters: FSC, SSC, FL-1, FL-2, FL-3, 20mW@488nm blue solid state laser, other laser light sources optional (UV, violet, green, red), WindowsTM XP FloMax (software for real time data acquisition, data display, and data evaluation), parallel 16 bit digital pulse processing. The CyFlow SL3 is a compact and dedicated portable Flow Cytometer for accurate and affordable cell analysis and true volumetric absolute counting in HIV Monitoring and AIDS patient follow-up by precise and direct CD4 and CD4% measurement.",http://www.partec.de/products/cyflowsl3.html,,,,,,CyFlow SL3,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400025,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CyFlow SL3,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0001346,ELISA measuring epitope specific interleukin-21 production by T cells,IL-21 release|ELISA,An assay of epitope specific interleukin-21 production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001237,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-21 production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific interleukin-21 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001346,,,,,,,,,,,,,,,,,,,,,,,,IL-21 release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific interleukin-21 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001386,epitope specific monocyte chemotactic protein-1 production by T cells,,A process of monocyte chemotactic protein-1 production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0071605|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of monocyte chemotactic protein-1 production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific monocyte chemotactic protein-1 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001386,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific monocyte chemotactic protein-1 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001103,rocker,,"A device that provides three-dimensional motion for biomedical applications (e.g., gel trays).",false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,"A device that provides three-dimensional motion for biomedical applications (e.g., gel trays).",PERSON: Erik Segerdell,,,,,,rocker,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000379,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001103,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,rocker,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0000192,microtiter plate,microplate,A microtiter_plate is a flat plate with multiple wells used as small test tubes.,false,,,http://purl.obolibrary.org/obo/OBI_0000967,,,,microplate,,,,,,,,,,,,,,,A microtiter_plate is a flat plate with multiple wells used as small test tubes.,http://en.wikipedia.org/wiki/Microtiter_plate,,,,,,microtiter plate,,"A microtiter plate with 6, 24, 96, 384 or 1536 sample wells used in the enzyme-linked immunosorbent assay (ELISA)",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/OBI_0000370,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000192,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,microtiter plate,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0001741,surface plasmon resonance assay measuring the on rate [kon] of a B cell epitope:antibody complex,on rate|surface plasmon resonance (SPR)|M^-1s^-1,A B cell epitope on rate measurement (kon) determination assay that uses a surface plasmon resonance assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001718,,,,,,,,,,,,,,,,,,,A B cell epitope on rate measurement (kon) determination assay that uses a surface plasmon resonance assay.,IEDB,,,,,,surface plasmon resonance assay measuring the on rate [kon] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001741,,,,,,,,,,,,,,,,,,,,,,,,on rate|surface plasmon resonance (SPR)|M^-1s^-1,,,,,,,,,,,,,,,,,,,,,,surface plasmon resonance assay measuring the on rate [kon] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000071,quantitative confidence value,,A data item which is used to indicate the degree of uncertainty about a measurement.,false,,,http://purl.obolibrary.org/obo/IAO_0000027,,,,,,,,,,,,,,,,,,,A data item which is used to indicate the degree of uncertainty about a measurement.,group:OBI,,,,,,quantitative confidence value,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000071,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,quantitative confidence value,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_1110059,ELISPOT assay measuring epitope specific interferon-gamma production by T cells,IFNg release|ELISPOT,An assay of epitope specific interferon-gamma production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001414,,,,,,,,,,,,,,,,,,,An assay of epitope specific interferon-gamma production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific interferon-gamma production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110059,,,,,,,,,,,,,,,,,,,,,,,,IFNg release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific interferon-gamma production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000416,cloning insert role,,cloning insert role is a role which inheres in DNA or RNA and is realized by the process of being inserted into a cloning vector in a cloning process.,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,,,cloning insert role is a role which inheres in DNA or RNA and is realized by the process of being inserted into a cloning vector in a cloning process.,OBII and Wikipedia,,,,,"Feb 20, 2009.  from Wikipedia:  cloning of any DNA fragment essentially involves four steps: DNA fragmentation with restriction endonucleases, ligation of DNA fragments to a vector, transfection, and screening/selection.  There are multiple processes involved, it is not just ""cloning process""",cloning insert role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000121,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000416,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cloning insert role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP: Role branch,,
http://purl.obolibrary.org/obo/OBI_0200143,subgraph in-degree calculation,,A network subgraph quality calculation in which an input data set describing subgraphs and directional relationship edges between subgraphs and other network objects is used to enumerate the number of unique relationships pointing into an individual subgraph.,false,,,http://purl.obolibrary.org/obo/OBI_0200137,,,,,,,,,,,,,,,,,,,A network subgraph quality calculation in which an input data set describing subgraphs and directional relationship edges between subgraphs and other network objects is used to enumerate the number of unique relationships pointing into an individual subgraph.,PERSON: Richard Scheuermann,,,,,,subgraph in-degree calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200143,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,subgraph in-degree calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Richard Scheuermann,,
http://purl.obolibrary.org/obo/OBI_0001416,biological activity assay measuring epitope specific tumor necrosis factor production by T cells,TNFa release|biological activity,An assay of epitope specific tumor necrosis factor superfamily cytokine production by T cells that detects tumor necrosis factor production.,false,,,http://purl.obolibrary.org/obo/OBI_0001400,,,,,,,,,,,,,,,,,,,An assay of epitope specific tumor necrosis factor superfamily cytokine production by T cells that detects tumor necrosis factor production.,IEDB,,,,,,biological activity assay measuring epitope specific tumor necrosis factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001416,,,,,,,,,,,,,,,,,,,,,,,,TNFa release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific tumor necrosis factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0200059,mhc binding prediction,,"An MHC binding prediction takes an input of a biomaterial sequence and through an analysis of this sequence, produces as output a prediction of the likelihood that the biomaterial will bind to an MHC molecule.",false,,,http://purl.obolibrary.org/obo/OBI_0200187,,http://purl.obolibrary.org/obo/OBI_0200081,,,,,,,,,,,,,,,,,"An MHC binding prediction takes an input of a biomaterial sequence and through an analysis of this sequence, produces as output a prediction of the likelihood that the biomaterial will bind to an MHC molecule.",PERSON: Helen Parkinson,,,,,,mhc binding prediction,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200059,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,mhc binding prediction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0001078,infrared image acquisition device,,An image acquisition device that is responsive to an infrared emissive target within a given field of view.,false,,,http://purl.obolibrary.org/obo/OBI_0000398,,,,,,,,,,,,,,,,,,,An image acquisition device that is responsive to an infrared emissive target within a given field of view.,United States Patent 4107530,,,,,,infrared image acquisition device,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453|http://purl.obolibrary.org/obo/OBI_0000397,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001078,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,infrared image acquisition device,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0000223,obsolete_blinded medication role,,Is a role which inheres in a material entity which is manufactured to be similar in appearance to a test material entity in e.g. a clinical trial to prevent participants from detecting which is the active and inactive substance,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,Is a role which inheres in a material entity which is manufactured to be similar in appearance to a test material entity in e.g. a clinical trial to prevent participants from detecting which is the active and inactive substance,,,,,,Will be modelled using a blinding process and specified output blinded medication instead,obsolete_blinded medication role,,Inert pill shaped like aspirin tablet|115 patients received ipilimumab and blinded medication,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,OBI:0000223,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_blinded medication role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel|Person:Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0002047,enzyme-linked antibody,,"A processed material that is comprised of an antibody that is covalently linked to an enzyme through bioconjugation. The enzyme can be used as a detection method when the enzyme's reaction produces a detectable signal, for example a color change when the substrate is added.",false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,,,,,,,,,,,,,,,,"A processed material that is comprised of an antibody that is covalently linked to an enzyme through bioconjugation. The enzyme can be used as a detection method when the enzyme's reaction produces a detectable signal, for example a color change when the substrate is added.",OBI,,,,,,enzyme-linked antibody,,Goat anti-Mouse IgG-HRP (horse radish peroxidase) is an antibody linked to the enzyme horseradish peroxidase (HRP) that catalyzes the conversion of chromogenic substrates into colored products producing light when acting on chemiluminescent substrates (ECL).,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002047,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0600038,,,enzyme-linked antibody,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Bjoern Peters, Randi Vita, James A. Overton",,
http://purl.obolibrary.org/obo/OBI_0400168,microtome,,"A microtome is a mechanical instrument used to cut biological specimens into very thin segments for further treatment (e.g. ISH) and ultimately microscopic or histologic examination. Most microtomes provide cooling facilities (cryo-microtome) and use a steel blade to cut a slice of defined thickness. Some are automatic, and some are driven by hand.",false,,,http://purl.obolibrary.org/obo/OBI_0000932,,,,,,,,,,,,,,,,,,,"A microtome is a mechanical instrument used to cut biological specimens into very thin segments for further treatment (e.g. ISH) and ultimately microscopic or histologic examination. Most microtomes provide cooling facilities (cryo-microtome) and use a steel blade to cut a slice of defined thickness. Some are automatic, and some are driven by hand.",PERSON: Daniel Schober,,,,,,microtome,,PMID: 9974145.Serial sectioning of thick tissue with a novel vibrating blade microtome. Brain Res Brain Res Protoc. 1999 Jan;3(3):302-7.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,http://purl.obolibrary.org/obo/OBI_0000379|http://purl.obolibrary.org/obo/OBI_0000372,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400168,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,microtome,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Phillippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000857,complementary nucleotide probe role,,A role played by a nucleic acid molecule that is used in a planned process for its ability to bind a nucleic acid molecules with complementary nucleotide sequence,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,,,A role played by a nucleic acid molecule that is used in a planned process for its ability to bind a nucleic acid molecules with complementary nucleotide sequence,,,,,,,complementary nucleotide probe role,,A primer in a PCR reaction. A probe on an Affymetrix chip.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000857,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_33696,,,,,,,,,,,,,,,,,complementary nucleotide probe role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0600038,addition of molecular label,labeling,"a material processing technique intended to add a molecular label to some input material entity, to allow detection of the molecular target of this label in a detection of molecular label assay",false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,labeling,,,,,,,,,,,,,,,"a material processing technique intended to add a molecular label to some input material entity, to allow detection of the molecular target of this label in a detection of molecular label assay","OBI developer call, 3-12-12",,,,,,addition of molecular label,,"The addition of phycoerytherin label to an anti-CD8 antibody, to label all antibodies. The addition of anti-CD8-PE to a population of cells, to label the subpopulation cells that are CD8+.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_1110109|http://purl.obolibrary.org/obo/REO_0000280,http://purl.obolibrary.org/obo/OBI_0001936,,,OBI:0600038,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,addition of molecular label,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_0000720,immunologic adjuvant role,,The role a material entity plays when it is co-administered with an immunogen in order to enhance the immune response to the immunogen.|,false,,,http://purl.obolibrary.org/obo/OBI_1110092,,,,,,,,,,,,,,,,,"Renamed from adjuvent role, to be a more specific useage for immunology, tracker https://sourceforge.net/tracker/?func=detail&atid=886178&aid=2887909&group_id=177891",,The role a material entity plays when it is co-administered with an immunogen in order to enhance the immune response to the immunogen.,"Vaccine Ontology, Wikipedia, OBI",,,,,"11Feb09:Vaccine Ontology Definition: Adjuvant boosts immune response of a vaccine or antigen in the host.  
the role 'adjuvant role' inheres in some 'material entity' and is realized by some 'immune response assay'.",immunologic adjuvant role,,"Adjuvants are pharmacological or immunological agents that modify the effect of other agents (e.g., drugs, vaccines) while having few if any direct effects when given by themselves.   http://en.wikipedia.org/wiki/Adjuvant",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000720,,,,,,,,,,,,,,,,,,"",,,,,,,,,,,,,,,,,,,,,,,,,,,,immunologic adjuvant role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP:  Role branch,,
http://purl.obolibrary.org/obo/OBI_0001542,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-13 production by T cells,IL-13 release|RNA/DNA detection,An assay of epitope specific interleukin-13 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001251,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-13 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-13 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001542,,,,,,,,,,,,,,,,,,,,,,,,IL-13 release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-13 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001979,fluorescence quenching binding assay,,A binding assay in which the proximity of two entities is monitored by measuring a fluorescent signal of one of the entities that gets reduced if the two entities are cliose to each other.,false,,,http://purl.obolibrary.org/obo/OBI_0001499,,,,,,,,,,,,,,,,,,,A binding assay in which the proximity of two entities is monitored by measuring a fluorescent signal of one of the entities that gets reduced if the two entities are cliose to each other.,IEDB,,,,,,fluorescence quenching binding assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001501,,,,,,,,,,,,,,,,OBI:0001979,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,fluorescence quenching binding assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/IAO_0000180,heatmap,,"A heatmap is a report graph which is a graphical representation of data
where the values taken by a variable(s) are shown as colors in a
two-dimensional map.",false,,,http://purl.obolibrary.org/obo/IAO_0000038,,,,,,,,,,,,,,,,,,,"A heatmap is a report graph which is a graphical representation of data
where the values taken by a variable(s) are shown as colors in a
two-dimensional map.",GROUP:OBI,,,,,,heatmap,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000180,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,heatmap,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:James Malone|PERSON:Chris Stoeckert|PERSON:Melanie Courtot,,
http://purl.obolibrary.org/obo/CHEBI_29237,deuterium atom,,"The stable isotope of hydrogen with relative atomic mass 2.014102 and a natural abundance of 0.0115 atom percent (from Greek deltaepsilonupsilontauepsilonrhoomicronnu, second).",false,,,http://purl.obolibrary.org/obo/CHEBI_23367|http://purl.obolibrary.org/obo/CHEBI_33250,,,,,,,,,,,,,,,,,,,"The stable isotope of hydrogen with relative atomic mass 2.014102 and a natural abundance of 0.0115 atom percent (from Greek deltaepsilonupsilontauepsilonrhoomicronnu, second).",,,,,,,deuterium atom,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:29237,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,deuterium atom,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/IAO_0000105,obsolete2_digital document,,A digital document is a digital entity consisting of an electronic file which can be rendered into human-readable form by one or more computational applications.  The digital document does not refer to the information content of the document but to an instance of the file.,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,A digital document is a digital entity consisting of an electronic file which can be rendered into human-readable form by one or more computational applications.  The digital document does not refer to the information content of the document but to an instance of the file.,group:OBI|OBI_0000195,,,,,"3/22/2009 Alan Ruttenberg, obsoleted per http://groups.google.com/group/information-ontology/browse_thread/thread/789ad4b7708d5cf4
superclass was 'digial entity'",obsolete2_digital document,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,IAO:0000105,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete2_digital document,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0000994,intravenous injection,,is the injection of a material entity (bearing the administered substance role) into the vein (bearing the target role) of an organism using a syringe,false,,,http://purl.obolibrary.org/obo/OBI_0000426|http://purl.obolibrary.org/obo/OBI_0600007,,http://purl.obolibrary.org/obo/OBI_0000434,,,,,,,,,,,,,,,,,is the injection of a material entity (bearing the administered substance role) into the vein (bearing the target role) of an organism using a syringe,,,,,,,intravenous injection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000994,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,intravenous injection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0001926,microRNA profiling assay,miRNA expression assay|microRNA expression assay,A transcription profiling assay in which aims to quantify the microRNA species within a biological sample.,false,,,http://purl.obolibrary.org/obo/OBI_0000424,,,,miRNA expression assay|microRNA expression assay,,,,,,,,,,,,,,,A transcription profiling assay in which aims to quantify the microRNA species within a biological sample.,Kolbert et al. Multi-Platform Analysis of MicroRNA Expression Measurements in RNA from Fresh Frozen and FFPE Tissues. PLoS One. 2013;8(1):e52517 [PMID: 23382819],,,,,,microRNA profiling assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001926,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,microRNA profiling assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001191,half maximal inhibitory concentration (IC50),,"Half maximal inhibitory concentration (IC50) is a scalar measurement datum that measures the effectiveness of a compound to competitively inhibit a given process, and corresponds to the concentration of the compound at which it reaches half of its maximum inhibitory effect.",false,,,http://purl.obolibrary.org/obo/IAO_0000032,,,,,,,,,,,,,,,,,,,"Half maximal inhibitory concentration (IC50) is a scalar measurement datum that measures the effectiveness of a compound to competitively inhibit a given process, and corresponds to the concentration of the compound at which it reaches half of its maximum inhibitory effect.",wikipedia,,,,,,half maximal inhibitory concentration (IC50),,"Interpolating that at a dose of IC50=12 nM, half of the binding of a comptetitive ligand is inhibited.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,http://purl.obolibrary.org/obo/UO_0000051,,,,,,,,,,,,,,,,,,,,,OBI:0001191,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001172,,,,,,,,,,,,,,,,half maximal inhibitory concentration (IC50),,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters; Randi Vita,,
http://purl.obolibrary.org/obo/OBI_1110172,intracellular cytokine staining assay measuring epitope specific interferon-gamma production by T cells,IFNg release|ICS,An assay of epitope specific interferon-gamma production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001414,,,,,,,,,,,,,,,,,,,An assay of epitope specific interferon-gamma production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific interferon-gamma production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110172,,,,,,,,,,,,,,,,,,,,,,,,IFNg release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific interferon-gamma production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000134,hardware testing objective,,"Hardware_testing_objective is a methodology_testing_objective role describing a study designed to examine the effects of using different hardware, e.g. scanner.",false,,,http://purl.obolibrary.org/obo/OBI_0000208,,,,,,,,,,,,,,,,,,,"Hardware_testing_objective is a methodology_testing_objective role describing a study designed to examine the effects of using different hardware, e.g. scanner.",,,,,,,hardware testing objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000134,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,hardware testing objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0001108,nucleic acid sequencer,,An device that is used to determine the order of nucleotides in nucleic acid sequences.,false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,An device that is used to determine the order of nucleotides in nucleic acid sequences.,PERSON: Erik Segerdell,,,,,,nucleic acid sequencer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001108,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,nucleic acid sequencer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001353,cytometric bead array assay measuring epitope specific tumor necrosis factor production by T cells,TNFa release|cytometric bead array,A T cell epitope specific tumor necrosis factor production assay that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001416|http://purl.obolibrary.org/obo/OBI_0001368,,,,,,,,,,,,,,,,,,,A T cell epitope specific tumor necrosis factor production assay that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific tumor necrosis factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001353,,,,,,,,,,,,,,,,,,,,,,,,TNFa release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific tumor necrosis factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001165,age since coitus measurement datum,,"An age measurement datum that is the result of the measurement of the age of an organism since coitus, the process of copulation that occurs during the process of sexual reproduction.",false,,,http://purl.obolibrary.org/obo/OBI_0001167,,,,,,,,,,,,,,,,,,,"An age measurement datum that is the result of the measurement of the age of an organism since coitus, the process of copulation that occurs during the process of sexual reproduction.",MO_783 coitus,,,,,,age since coitus measurement datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001165,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,age since coitus measurement datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/CHEBI_16991,deoxyribonucleic acid,,"High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms.",false,,,http://purl.obolibrary.org/obo/CHEBI_33696,,,,,,,,,,,,,,,,,,,"High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms.",,,,,,,deoxyribonucleic acid,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:16991,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,deoxyribonucleic acid,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0100039,obsolete_fragment derived from protein,,A material entity which is derived from a  protein,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,A material entity which is derived from a  protein,GROUP: IEDB,,,,,"original term: protein fragment split into synthetic polypeptide and fragment derived from protein
THE DEFINITION OF THIS SUGGESTS WE COVER THIS ALREADY IN PEPTIDE/POLYPETIDE. DO WE NEED THIS AND CAN WE DEAL WITH IT IN SOME OTHER WAY?  JAMES|PRS:22022008. result from protocol_application where input=protein and output=polypeptide or peptide (to capture: derives_from protein)|BP:03/21/2010:obsoleted as the class is no longer necessary, and we would otherwise need all kinds of 'fragment derived from' classes. Instead, use composite terms with the relationship 'derived from' some protein OR derived from some part_of protein.",obsolete_fragment derived from protein,,"the peptide with sequence SIINFEKL, which is eluted from a cell expressing hen egg lysozyme",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,OBI:0100039,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_fragment derived from protein,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0400006,A40-MiniFCM,,"A A40-MiniFCM is a flow_cytometer_analyser that allows for the choice of one of four lasers (375nm, 405nm,488nm, 532nm, 635nm), and PMTs and filters for collecting up to four parameters. It uses digital electronics. A military version of this cytometer is available as well. The A40-MiniFCM is geared towards the most demanding applications such as archaea, bacteria and large virus.",false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,,,,,,,,,,,,,,,,"A A40-MiniFCM is a flow_cytometer_analyser that allows for the choice of one of four lasers (375nm, 405nm,488nm, 532nm, 635nm), and PMTs and filters for collecting up to four parameters. It uses digital electronics. A military version of this cytometer is available as well. The A40-MiniFCM is geared towards the most demanding applications such as archaea, bacteria and large virus.",http://www.apogeeflow.com/flow_cytometry_products.htm,,,,,,A40-MiniFCM,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400006,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,A40-MiniFCM,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0400062,krypton ion laser,,"A krypton-ion laser is an ion laser that uses krypton as the lasing medium. These lasers can emit at 468, 476, 482, 520, 531, 568, 647 (the most powerful line), and 676 nm all at once. They have much lower gain than argon lasers however.",false,,,http://purl.obolibrary.org/obo/OBI_0400060,,,,,,,,,,,,,,,,,,,"A krypton-ion laser is an ion laser that uses krypton as the lasing medium. These lasers can emit at 468, 476, 482, 520, 531, 568, 647 (the most powerful line), and 676 nm all at once. They have much lower gain than argon lasers however.",John Quinn,,,,,,krypton ion laser,,Lexel 95L krypton laser,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400062,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,krypton ion laser,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0400050,Guava Personal Cell Analysis,Guava_PCA,"A  Guava_Personal_Cell_Analysis System is a flow_cytometer_analyser that includes a single 532 nm laser, and filters and PMTs to collect up to 2 fluorescent parameters. It includes a photodiode forward scatter collector. Guava cytometers use aspiration instead of fluid systems to transport cells within the machine. The PCA96 uses only tubes to introduce specimen. The Guava PCA cytometer is a small portable cytometer particularly useful for field measurement.",false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,Guava_PCA,,,,,,,,,,,,,,,"A  Guava_Personal_Cell_Analysis System is a flow_cytometer_analyser that includes a single 532 nm laser, and filters and PMTs to collect up to 2 fluorescent parameters. It includes a photodiode forward scatter collector. Guava cytometers use aspiration instead of fluid systems to transport cells within the machine. The PCA96 uses only tubes to introduce specimen. The Guava PCA cytometer is a small portable cytometer particularly useful for field measurement.",http://www.guavatechnologies.com/main/products/PCA-new.cfm,,,,,,Guava Personal Cell Analysis,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400050,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Guava Personal Cell Analysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0001366,epitope specific RANTES production by T cells,,A process of RANTES production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0071609|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of RANTES production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific RANTES production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001366,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific RANTES production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/IAO_0000033,directive information entity,,An information content entity whose concretizations indicate to their bearer how to realize them in a process.,false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,,,,,,,,,,,,,,,,An information content entity whose concretizations indicate to their bearer how to realize them in a process.,,,,,,"8/6/2009 Alan Ruttenberg: Changed label from ""information entity about a realizable"" after discussions at ICBO|Werner pushed back on calling it realizable information entity as it isn't realizable. However this name isn't right either. An example would be a recipe. The realizable entity would be a plan, but the information entity isn't about the plan, it, once concretized, *is* the plan. -Alan|2013-05-30 Alan Ruttenberg: What differentiates a directive information entity from an information concretization is that it can have concretizations that are either qualities or realizable entities. The concretizations that are realizable entities are created when an individual chooses to take up the direction, i.e. has the intention to (try to) realize it.|2009-03-16: provenance: a term realizable information entity was proposed for OBI (OBI_0000337) , edited by the PlanAndPlannedProcess branch. Original definition was  ""is the specification of a process that can be concretized and realized by an actor"" with alternative term  ""instruction"".It has been subsequently moved to IAO where the objective for which the original term was defined was satisfied with the definitionof this, different, term.",directive information entity,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000033,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000017,,,,,,,,,,,,,,,,directive information entity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters|PERSON: Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0001262,epitope specific interleukin-27 production by T cells,,A process of interleukin-27 production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/OBI_0001193|http://purl.obolibrary.org/obo/GO_0032631,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of interleukin-27 production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific interleukin-27 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001262,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific interleukin-27 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001853,DNase I hypersensitive sites sequencing assay,DNase-seq assay|DNase-seq,"An assay to identify the location of regulatory regions, based on the genome-wide sequencing of regions super sensitive to cleavage by DNase I.",false,,,http://purl.obolibrary.org/obo/OBI_0000626,,http://purl.obolibrary.org/obo/OBI_0001398,,DNase-seq assay|DNase-seq,,,,,,,,,,,,,,,"An assay to identify the location of regulatory regions, based on the genome-wide sequencing of regions super sensitive to cleavage by DNase I.",http://en.wikipedia.org/wiki/DNase-Seq,,,,,,DNase I hypersensitive sites sequencing assay,,"Sabo, et al. Discovery of functional noncoding elements by digital analysis of chromatin structure. Proc Natl Acad Sci U S A. 2004 Nov 30;101(48):16837-42. [PMID:15550541]",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0600023|http://purl.obolibrary.org/obo/OBI_0000711|http://purl.obolibrary.org/obo/OBI_0000626,http://purl.obolibrary.org/obo/OBI_0400103,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001573,,,OBI:0001853,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNase I hypersensitive sites sequencing assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/CHEBI_33359,rhodium atom,,A cobalt group element atom that has formula Rh.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,A cobalt group element atom that has formula Rh.,,,,,,,rhodium atom,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:33359,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,rhodium atom,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000816,micro electrode,micro electrode measuring device,An electrode of very fine caliber consisting usually of a fine wire or a glass tube of capillary diameter drawn to a fine point and filled with saline or a metal used in physiological experiments to stimulate or record action currents of extracellular or intracellular origin in the nervous system.,false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,micro electrode measuring device,,,,,,,,,,,,,,,An electrode of very fine caliber consisting usually of a fine wire or a glass tube of capillary diameter drawn to a fine point and filled with saline or a metal used in physiological experiments to stimulate or record action currents of extracellular or intracellular origin in the nervous system.,"Jessica Turner, Dirk Derom",,,,,,micro electrode,,A micro-electrode recording device used to record extracellular action potentialsin monkey caudate nucleus,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000816,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000245,,,,,,micro electrode,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Helen Parkinson, Jessica Turner, Dirk Derom",,
http://purl.obolibrary.org/obo/OBI_0001223,cytometric bead array assay measuring epitope specific interleukin-1 beta production by T cells,IL-1b release|cytometric bead array,An assay of epitope specific interleukin-1 beta production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001449,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-1 beta production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific interleukin-1 beta production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001223,,,,,,,,,,,,,,,,,,,,,,,,IL-1b release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific interleukin-1 beta production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001925,chromatin immunoprecipitation with exonuclease sequencing assay,ChIP-exo assay,A ChIP-seq assay to identify protein binding sites using an exonuclease  to provide greater binding resolution of immunoprecipitation assay by genome wide sequencing.,false,,,http://purl.obolibrary.org/obo/OBI_0000716,,,,ChIP-exo assay,,,,,,,,,,,,,,,A ChIP-seq assay to identify protein binding sites using an exonuclease  to provide greater binding resolution of immunoprecipitation assay by genome wide sequencing.,Rhee et al. Comprehensive Genome-wide Protein-DNA Interactions Detected at Single-Nucleotide Resolution. Cell. 2011 Dec;147(6):1408-19. [PMID:22153082],,,,,,chromatin immunoprecipitation with exonuclease sequencing assay,,Rhee et al. Comprehensive Genome-wide Protein-DNA Interactions Detected at Single-Nucleotide Resolution. Cell. 2011 Dec;147(6):1408-19. [PMID:22153082],,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000800|http://purl.obolibrary.org/obo/OBI_0600050,http://purl.obolibrary.org/obo/OBI_0400114,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001573,,,OBI:0001925,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,chromatin immunoprecipitation with exonuclease sequencing assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000656,data set of predicted values according to fitted curve,,A data set which is the output of a curve fitting data transformation in which the aim is to find a curve which matches a series of data points and possibly other constraints.,false,,,http://purl.obolibrary.org/obo/IAO_0000100,,,,,,,,,,,,,,,,,,,A data set which is the output of a curve fitting data transformation in which the aim is to find a curve which matches a series of data points and possibly other constraints.,,,,,,,data set of predicted values according to fitted curve,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000656,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,data set of predicted values according to fitted curve,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: James Malone|PERSON: Monnie McGee,,
http://purl.obolibrary.org/obo/OBI_0001410,translation profiling design,,"A study design in which surface-bound, translationally competent ribosome complexes are used to generate a translation profile for mRNA, where mRNA may be a single molecular species, or a combination of species, including complex mixtures such as those found in the set of mRNAs isolated from a cell or tissue. One or more components of the surface-bound ribosome complex may be labeled at specific positions to permit analysis of multiple or single molecules for determination of ribosomal conformational changes and translation kinetics. Translation profiles are used as the basis for comparison of an mRNA or set of mRNA species. The translation profile can be used to determine such characteristics as kinetics of initiation, kinetic of elongation, identity of the polypeptide product, and the like. Analysis of translation profiles may be used to determine differential gene expression, optimization of mRNA sequences for expression, screening drug candidates for an effect on translation.",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A study design in which surface-bound, translationally competent ribosome complexes are used to generate a translation profile for mRNA, where mRNA may be a single molecular species, or a combination of species, including complex mixtures such as those found in the set of mRNAs isolated from a cell or tissue. One or more components of the surface-bound ribosome complex may be labeled at specific positions to permit analysis of multiple or single molecules for determination of ribosomal conformational changes and translation kinetics. Translation profiles are used as the basis for comparison of an mRNA or set of mRNA species. The translation profile can be used to determine such characteristics as kinetics of initiation, kinetic of elongation, identity of the polypeptide product, and the like. Analysis of translation profiles may be used to determine differential gene expression, optimization of mRNA sequences for expression, screening drug candidates for an effect on translation.",Group: ArrayExpress production team,,,,,,translation profiling design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000131,,,,,,,,,,,,,,,,OBI:0001410,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,translation profiling design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/BFO_0000015,process,,"p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])|An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t.",false,,,http://purl.obolibrary.org/obo/BFO_0000003,,,,,,,Process,process,,,,,,,,,,,"p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])|An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t.",,,,,,"BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war)",process,,"the life of an organism|the course of a disease|the flight of a bird|a process of sleeping|your process of aging.|a process of cell-division, \ a beating of the heart|a process of meiosis",,,,,,,,(iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000015,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,process,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0001816,cytokine production,,"The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,"The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,cytokine production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0001816,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,cytokine production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0600013,information acquisition,data collection,An acquisition in which possession of information is gained.,false,,,http://purl.obolibrary.org/obo/OBI_0600008,,,,data collection,,,,,,,,,,,,,,,An acquisition in which possession of information is gained.,OBI branch derived,,,,,"This excludes processes that create or change information, such as assays and data transformations.",information acquisition,,"Gathering all influenza HA sequences from GenBank, Retrieveing HLA allele frequencies in the North American populations from dbMHC",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000030,,,OBI:0600013,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,information acquisition,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001554,rate measurement datum,,A scalar measurement datum that represents the number of events occuring over a time interval,false,,,http://purl.obolibrary.org/obo/IAO_0000032,,,,,,,,,,,,,,,,,,,A scalar measurement datum that represents the number of events occuring over a time interval,IEDB,,,,,,rate measurement datum,,The rate of disassociation of a peptide from a complex with an MHC molecule measured by the ratio of bound and unbound peptide per unit of time.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001554,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,rate measurement datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Bjoern Peters, Randi Vita",,
http://purl.obolibrary.org/obo/UBERON_0000029,lymph node,,"Any of the rounded masses of lymphoid tissue that are surrounded by a capsule of connective tissue, are distributed along the lymphatic vessels, and contain numerous lymphocytes which filter the flow of lymph.",false,,,http://purl.obolibrary.org/obo/CARO_0001008,,,,,,,,,,,,,,,,,,,"Any of the rounded masses of lymphoid tissue that are surrounded by a capsule of connective tissue, are distributed along the lymphatic vessels, and contain numerous lymphocytes which filter the flow of lymph.",,,,,,,lymph node,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UBERON:0000029,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uberon.owl,,,,,,,,,,,,,,,,,,,lymph node,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000902,post mortem specimen,,a specimen that was taken from a dead organism,false,,,http://purl.obolibrary.org/obo/OBI_0001506,,,,,,,,,,,,,,,,,,,a specimen that was taken from a dead organism,MO_416 postmortem,,,,,,post mortem specimen,,the spleen taken from a dead mouse,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000902,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,post mortem specimen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000821,filled capsule,,A pill in the form of a small rounded gelatinous container with medicine inside.,false,,,http://purl.obolibrary.org/obo/OBI_0000827,,,,,,,,,,,,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,,A pill in the form of a small rounded gelatinous container with medicine inside.,http://www.golovchenko.org/cgi-bin/wnsearch?q=capsule#2n,,,,,,filled capsule,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000798,,,,,,,,,,,,,,,,OBI:0000821,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,filled capsule,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0001555,purified MHC binding assay measuring binding of a MHC:ligand complex,qualitative binding|purified MHC,A MHC binding qualitative binding to ligand assay using MHC in a purified MHC molecule preparation.,false,,,http://purl.obolibrary.org/obo/OBI_0002072,,,,,,,,,,,,,,,,,,,A MHC binding qualitative binding to ligand assay using MHC in a purified MHC molecule preparation.,IEDB,,,,,,purified MHC binding assay measuring binding of a MHC:ligand complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001555,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|purified MHC,,,,,,,,,,,,,,,,,,,,,,purified MHC binding assay measuring binding of a MHC:ligand complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001831,ELISA measuring epitope specific interleukin-17F production by T cells,IL-17F release|ELISA,A T cell epitope specific interleukin-17F production assay that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_1110162|http://purl.obolibrary.org/obo/OBI_0001772,,,,,,,,,,,,,,,,,,,A T cell epitope specific interleukin-17F production assay that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific interleukin-17F production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001831,,,,,,,,,,,,,,,,,,,,,,,,IL-17F release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific interleukin-17F production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0400115,spectrophotometer,,"A spectrophotometer is an instrument that measures the intensity of light as a function of the color, or more specifically, the wavelength of light, transmitted by a substance.",false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,"A spectrophotometer is an instrument that measures the intensity of light as a function of the color, or more specifically, the wavelength of light, transmitted by a substance.",MO,,,,,,spectrophotometer,,Helios Gamma Spectrophotometer,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400115,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,spectrophotometer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Melanie Courtot|Trish Whetzel,,
http://purl.obolibrary.org/obo/OBI_0001734,calorimetry assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex ,dissociation constant KD|calorimetry|nM,A B cell epitope equilibrium dissociation constant (KD) determination assay that uses a calorimetric binding assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001708,,,,,,,,,,,,,,,,,,,A B cell epitope equilibrium dissociation constant (KD) determination assay that uses a calorimetric binding assay.,IEDB,,,,,,calorimetry assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex ,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001734,,,,,,,,,,,,,,,,,,,,,,,,dissociation constant KD|calorimetry|nM,,,,,,,,,,,,,,,,,,,,,,calorimetry assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001796,intracellular cytokine staining assay measuring epitope specific IP-10 production by T cells,CXCL10/IP-10 release|ICS,An assay of epitope specific IP-10 production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001308,,,,,,,,,,,,,,,,,,,An assay of epitope specific IP-10 production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific IP-10 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001796,,,,,,,,,,,,,,,,,,,,,,,,CXCL10/IP-10 release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific IP-10 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000723,DNA sequencing by ligation,,is a DNA sequencing which relies on DNA ligase activity to perform chain extension during the sequencing reaction step.,false,,,http://purl.obolibrary.org/obo/OBI_0000626,,,,,,,,,,,,,,,,,,,is a DNA sequencing which relies on DNA ligase activity to perform chain extension during the sequencing reaction step.,,,,,,PERSON: Philippe Rocca-Serra,DNA sequencing by ligation,,"PMID: 19546169. Sequence and structural variation in a human genome uncovered by short-read, massively parallel ligation sequencing using two base encoding.
McKernan KJ, Peckham HE, Costa G, McLaughlin S, Tsung E, Fu Y, 
Clouser C, Dunkan C, Ichikawa J, Lee C, Zhang Z, Sheridan A, Fu H, Ranade S, Dimilanta E, Sokolsky T, Zhang L, Hendrickson C, Li B, Kotler L, Stuart J, Malek J, Manning J, Antipova A, Perez D, Moore M, Hayashibara K, Lyons M, Beaudoin R, Coleman B, Laptewicz M, Sanicandro A, Rhodes M, De La Vega F, Gottimukkala RK, Hyland F, Reese M, Yang S, Bafna V, Bashir A, Macbride A, Aklan C, Kidd JM, Eichler EE, Blanchard AP. Genome Res. 2009 Jun 22.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/PR_000023089,,,,OBI:0000723,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNA sequencing by ligation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0005246,injection function,,"The function of a device realized when administering a substance in vivo, applied particularly to the forcible insertion of a liquid or gas by means of a syringe, pump, etc.",false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,"The function of a device realized when administering a substance in vivo, applied particularly to the forcible insertion of a liquid or gas by means of a syringe, pump, etc.",adapted from WEB: http://www.dictionary.net/injection,,,,,,injection function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0005246,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,injection function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot|PERSON: Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0400143,fluorometer,,"A fluorometer is an instrument for the detection and measurement of parameters of fluoresence, which in turn are used to identify the presence and amount of specific molecules in the sample.",false,,,http://purl.obolibrary.org/obo/OBI_0400115,,,,,,,,,,,,,,,,,,,"A fluorometer is an instrument for the detection and measurement of parameters of fluoresence, which in turn are used to identify the presence and amount of specific molecules in the sample.",OBI,,,,,,fluorometer,,"laser/detector in capillary electrophoresis apparatus, NanoDrop ND-3300",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400143,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,fluorometer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Allyson Lister|Kevin Lister,,
http://purl.obolibrary.org/obo/OBI_0001092,computer cluster,,"A group of linked computers, working together closely so that in many respects they form a single computer.",false,,,http://purl.obolibrary.org/obo/OBI_0400107,,,,,,,,,,,,,,,,,,,"A group of linked computers, working together closely so that in many respects they form a single computer.",http://en.wikipedia.org/wiki/Cluster_(computing),,,,,,computer cluster,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001092,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,computer cluster,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0000560,ion exchange column,,An ion exchange column is a chromatography column that is used in ion exchange chromatography and anion or cation exchange resins to enable separation.,false,,,http://purl.obolibrary.org/obo/OBI_0000038,,,,,,,,,,,,,,,,,,,An ion exchange column is a chromatography column that is used in ion exchange chromatography and anion or cation exchange resins to enable separation.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01105,,,,,,ion exchange column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000560,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ion exchange column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001857,RNP (ribonuclear particle) immunoprecipitation high- throughput sequencing assay,RIP-seq assay|RIP-seq,An assay that combines immunoprecipitation of an RNA-binding protein and RNA-seq to identify mRNAs associated with selected RNA binding proteins (RBPs).,false,,,http://purl.obolibrary.org/obo/OBI_0600047|http://purl.obolibrary.org/obo/OBI_0000443,,http://purl.obolibrary.org/obo/OBI_0000437|http://purl.obolibrary.org/obo/OBI_0001854,,RIP-seq assay|RIP-seq,,,,,,,,,,,,,,,An assay that combines immunoprecipitation of an RNA-binding protein and RNA-seq to identify mRNAs associated with selected RNA binding proteins (RBPs).,Zhao et al. Genome-wide identification of polycomb-associated RNAs by RIP-seq. Molecular Cell (2010) vol. 40 (6) pp. 939-53 [PMID:21172659],,,,,,RNP (ribonuclear particle) immunoprecipitation high- throughput sequencing assay,,Zhao et al. Genome-wide identification of polycomb-associated RNAs by RIP-seq. Molecular Cell (2010) vol. 40 (6) pp. 939-53 [PMID:21172659],,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000800|http://purl.obolibrary.org/obo/OBI_0001177|http://purl.obolibrary.org/obo/OBI_0000690|http://purl.obolibrary.org/obo/OBI_0000711,http://purl.obolibrary.org/obo/OBI_0400103|http://purl.obolibrary.org/obo/OBI_0400114,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001573,,,OBI:0001857,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,RNP (ribonuclear particle) immunoprecipitation high- throughput sequencing assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/BFO_0000001,entity,,,false,,,http://www.w3.org/2002/07/owl#Thing,,,,,,,Entity,entity,,,,,,,,,,,,,,,,,"BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81|Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf",entity,An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001]),your body mass index|Verdi’s Requiem|Julius Caesar|the Second World War,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000001,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,entity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OGMS_0000090,treatment,,A processual entity whose completion is hypothesized (by a healthcare provider) to alleviate the signs and symptoms associated with a disorder,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,,,A processual entity whose completion is hypothesized (by a healthcare provider) to alleviate the signs and symptoms associated with a disorder,,,,,,,treatment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OGMS:0000090,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ogms.owl,,,,,,,,,,,,,,,,,,,treatment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001915,DNA replication timing by array assay,Repli-chip assay|Repli-chip,An assay in which timing of DNA replication is quantified as a function of genome position using array technology.,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,http://purl.obolibrary.org/obo/OBI_0001916,,Repli-chip assay|Repli-chip,,,,,,,,,,,,,,,An assay in which timing of DNA replication is quantified as a function of genome position using array technology.,Hiranti et al. Global reorganization of replication domains during embryonic stem cell differentiation. PLoS Biol. 2008 October 7;6(10):e245 [PMID:18842067],,,,,,DNA replication timing by array assay,,Hiranti et al. Global reorganization of replication domains during embryonic stem cell differentiation. PLoS Biol. 2008 October 7;6(10):e245 [PMID:18842067],,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001914|http://purl.obolibrary.org/obo/OBI_0000690|http://purl.obolibrary.org/obo/OBI_0000711,http://purl.obolibrary.org/obo/OBI_0400148|http://purl.obolibrary.org/obo/OBI_0400099,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_472552,,,,OBI:0001915,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNA replication timing by array assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/GO_0043316,cytotoxic T cell degranulation,,The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell.,false,,,http://purl.obolibrary.org/obo/GO_0001906,,,,,,,,,,,,,,,,,,,The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell.,,,,,,,cytotoxic T cell degranulation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0043316,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,cytotoxic T cell degranulation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000049,mass spectrometer,,"A mass spectrometer is an instrument which is used to measure the mass to charge ratio of ions. All mass spectrometers consist of three basic parts: an ion source, a mass analyzer, and a detector system. The stages within the mass spectrometer are: 1. Production of ions from the sample 2. Separation of ions with different masses 3. Detection of the number of ions of each mass produced 4.Collection of data to generate the mass spectrum",false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,http://purl.obolibrary.org/obo/OBI_0000654,,,,,,,,,,,,,"A mass spectrometer is an instrument which is used to measure the mass to charge ratio of ions. All mass spectrometers consist of three basic parts: an ion source, a mass analyzer, and a detector system. The stages within the mass spectrometer are: 1. Production of ions from the sample 2. Separation of ions with different masses 3. Detection of the number of ions of each mass produced 4.Collection of data to generate the mass spectrum",http://en.wikipedia.org/wiki/Mass_spectrometry,,,,,,mass spectrometer,,LCQ Fleet Ion Trap MSn manufactured by thermo fisher scientific,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000049,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,mass spectrometer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Frank Gibson,,
http://purl.obolibrary.org/obo/OBI_0001129,voltage clamp device,,"A device that is used to measure the ion currents across the membrane of excitable cells, such as neurons, while holding the membrane voltage at a set level.",false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,"A device that is used to measure the ion currents across the membrane of excitable cells, such as neurons, while holding the membrane voltage at a set level.",http://en.wikipedia.org/wiki/Voltage_clamp,,,,,,voltage clamp device,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001129,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,voltage clamp device,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/CHEBI_52673,Alexa Fluor 555,,"A fluorescent dye of absorption wavelength 555 nm and emission wavelength 565 nm, derived from a 3,6-diaminoxanthene-4,5-disulfate.",false,,,http://purl.obolibrary.org/obo/REO_0000280,,,,,,,,,,,,,,,,,,,"A fluorescent dye of absorption wavelength 555 nm and emission wavelength 565 nm, derived from a 3,6-diaminoxanthene-4,5-disulfate.",,,,,,,Alexa Fluor 555,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/REO_0000171,,,,,,,,,,,,CHEBI:52673,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,Alexa Fluor 555,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000601,chromatography consumable,,A chromatography consumable is a consumable that is used in a chromatography experiment.,false,,,http://purl.obolibrary.org/obo/OBI_0000048,,,,,,,,,,,,,,,,,chromatography device,,A chromatography consumable is a consumable that is used in a chromatography experiment.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01115,,,,,,chromatography consumable,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000601,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,chromatography consumable,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001567,cell lysate MHC direct binding assay measuring binding off rate [koff] of a MHC:ligand complex using radioactivity detection,off rate|lysate MHC/direct/radioactivity|1/s,A cell lysate MHC ligand binding off rate measurement (koff) determination assay that uses radioactivity detection to measure direct ligand binding.,false,,,http://purl.obolibrary.org/obo/OBI_0001491|http://purl.obolibrary.org/obo/OBI_0001993,,,,,,,,,,,,,,,,,,,A cell lysate MHC ligand binding off rate measurement (koff) determination assay that uses radioactivity detection to measure direct ligand binding.,IEDB,,,,,,cell lysate MHC direct binding assay measuring binding off rate [koff] of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001567,,,,,,,,,,,,,,,,,,,,,,,,off rate|lysate MHC/direct/radioactivity|1/s,,,,,,,,,,,,,,,,,,,,,,cell lysate MHC direct binding assay measuring binding off rate [koff] of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000582,Bruker LC-NMR/MS platform,,Includes the connection to a high-resolution TOF-LC-MS system.,false,,,http://purl.obolibrary.org/obo/OBI_0000596,,,,,,,,,,,,,,,,,NMR instrument|hyphenated NMR instrument platform,,Includes the connection to a high-resolution TOF-LC-MS system.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400277,,,,,,Bruker LC-NMR/MS platform,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000582,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker LC-NMR/MS platform,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001466,intracellular cytokine staining assay measuring epitope specific interleukin-12 production by T cells,IL-12 release|ICS,An assay of epitope specific interleukin-12 production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001391,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-12 production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-12 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001466,,,,,,,,,,,,,,,,,,,,,,,,IL-12 release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-12 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000696,AB SOLiD System,,is a DNA sequencer which is manufactured by Applied Biosystems and which enable DNA sequencing by ligation,false,,,http://purl.obolibrary.org/obo/OBI_0400103,,,,,,,,,,,,,,,,,,,is a DNA sequencer which is manufactured by Applied Biosystems and which enable DNA sequencing by ligation,Applied Biosystems,,,,,,AB SOLiD System,,"PMID: 19336255. RNA-Seq-quantitative measurement of expression through massively parallel RNA-sequencing. Wilhelm BT, Landry JR. Methods. 2009 Jul;48(3):249-57.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000696,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,AB SOLiD System,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001397,cytometric bead array assay measuring epitope specific granulocyte colony stimulating factor production by T cells,G-CSF release|cytometric bead array,An assay of epitope specific granulocyte colony stimulating factor production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001600,,,,,,,,,,,,,,,,,,,An assay of epitope specific granulocyte colony stimulating factor production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific granulocyte colony stimulating factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001397,,,,,,,,,,,,,,,,,,,,,,,,G-CSF release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific granulocyte colony stimulating factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0200135,edge quality calculation,,A network analysis in which an input data set describing node objects and edge relationships between node objects is used to determine the output quality of one of the edge relationships in the network.,false,,,http://purl.obolibrary.org/obo/OBI_0200080,,,,,,,,,,,,,,,,,,,A network analysis in which an input data set describing node objects and edge relationships between node objects is used to determine the output quality of one of the edge relationships in the network.,PERSON: Richard Scheuermann,,,,,,edge quality calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200135,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,edge quality calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Richard Scheuermann,,
http://purl.obolibrary.org/obo/CHEBI_472552,5-bromo-2'-deoxyuridine,,A pyrimidine 2'-deoxyribonucleoside compound having 5-bromouracil as the nucleobase.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,A pyrimidine 2'-deoxyribonucleoside compound having 5-bromouracil as the nucleobase.,,,,,,,5-bromo-2'-deoxyuridine,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:472552,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,5-bromo-2'-deoxyuridine,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001978,immunoblot assay,,"An analyte assay that detects specific molecules in an input material by separating it using gel electrophoresis, transfering the separated molecules to a membrane, and staining them with  antibodies specific to the analyte molecules.",false,,,http://purl.obolibrary.org/obo/OBI_0000443,,,,,,,,,,,,,,,,,,,"An analyte assay that detects specific molecules in an input material by separating it using gel electrophoresis, transfering the separated molecules to a membrane, and staining them with  antibodies specific to the analyte molecules.",IEDB,,,,,,immunoblot assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0600053,,,,,,,,,,,,,,,,OBI:0001978,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,immunoblot assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000377,perturb function,,"A perturb function is a function that disrupts the normal function of a system induced through either internal or external means.  External means of perturbation include: (1) displacement fields in the physical sense - e.g., temperature change, osmotic shock, pressure change; (2) application of small molecules such as drugs or toxins to perturb the function of specific pathways or application of surfactants to perturb the normal function of plasma membrane.  Internal means of perturbation include: (1) manipulation of gene function via gene knockout or transcript knockdown via RNAi; (2) directed genetic mutation leading to minimal aa alterations that interfere with peptide function.",false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,"A perturb function is a function that disrupts the normal function of a system induced through either internal or external means.  External means of perturbation include: (1) displacement fields in the physical sense - e.g., temperature change, osmotic shock, pressure change; (2) application of small molecules such as drugs or toxins to perturb the function of specific pathways or application of surfactants to perturb the normal function of plasma membrane.  Internal means of perturbation include: (1) manipulation of gene function via gene knockout or transcript knockdown via RNAi; (2) directed genetic mutation leading to minimal aa alterations that interfere with peptide function.",http://en.wikipedia.org/wiki/Perturbation_biology,,,,,,perturb function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000377,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,perturb function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bill Bug|Daniel Schober|Frank Gibson|Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0001298,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-21 production by T cells,IL-21 release|RNA/DNA detection,An assay of epitope specific interleukin-21 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001237,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-21 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-21 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001298,,,,,,,,,,,,,,,,,,,,,,,,IL-21 release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-21 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0200024,loess group transformation,,"A loess group transformation is a loess transformation where the input is partitioned into groups and for each group a loess fitting is performed, utilizing a subset of (or possibly all of) the data points in that group. Thus, a collection of loess curves y=f_i(x) is generated, one per group. Each (x, y) in the input is transformed into (x, y-f_i(x)), where f_i(x) is the curve corresponding to the group to which that data point belongs.",false,,,http://purl.obolibrary.org/obo/OBI_0200071,,,,,,,,,,,,,,,,,,,"A loess group transformation is a loess transformation where the input is partitioned into groups and for each group a loess fitting is performed, utilizing a subset of (or possibly all of) the data points in that group. Thus, a collection of loess curves y=f_i(x) is generated, one per group. Each (x, y) in the input is transformed into (x, y-f_i(x)), where f_i(x) is the curve corresponding to the group to which that data point belongs.",OTHER: Editor's generalization based on MGED Ontology term,,,,,,loess group transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200024,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,loess group transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Melanie Courtot|Elisabetta Manduchi|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001523,cytometric bead array assay measuring epitope specific interleukin-17F production by T cells,IL-17F release|cytometric bead array,A T cell epitope specific interleukin-17F production assay that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001296|http://purl.obolibrary.org/obo/OBI_0001772,,,,,,,,,,,,,,,,,,,A T cell epitope specific interleukin-17F production assay that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific interleukin-17F production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001523,,,,,,,,,,,,,,,,,,,,,,,,IL-17F release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific interleukin-17F production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0002085,transcript expression location detection by hybridization chain reaction,transcript expression location detection by fluorescent HCR.,"An in-situ hybridization in which the location (e.g. anatomical/tissue) of a transcript is detected by a multiplexed fluorescent in situ hybridization, based on orthogonal amplification with hybridization chain reactions (HCR). RNA probes complementary to mRNA targets trigger chain reactions in which fluorophore-labeled RNA hairpins self-assemble into tethered fluorescent amplification polymers.",false,,,http://purl.obolibrary.org/obo/OBI_0001686,,,,transcript expression location detection by fluorescent HCR.,,,,,,,,,,,,,,,"An in-situ hybridization in which the location (e.g. anatomical/tissue) of a transcript is detected by a multiplexed fluorescent in situ hybridization, based on orthogonal amplification with hybridization chain reactions (HCR). RNA probes complementary to mRNA targets trigger chain reactions in which fluorophore-labeled RNA hairpins self-assemble into tethered fluorescent amplification polymers.",PMID 21037591,,,,,See tracker #783,transcript expression location detection by hybridization chain reaction,,"PMID 25977364: ""Multiplexed imaging of mRNA expression using fluorescent hybridization chain reaction (HCR) quantitatively confirmed the expression profiles of lead cells""",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002085,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,transcript expression location detection by hybridization chain reaction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Paul D. Thomas, Yang Chai",,
http://purl.obolibrary.org/obo/OBI_0001192,epitope specific immune intervention,,An administration in vivo to either actively or passively immunize an organism in order to induce a response against a specific immune epitope,false,,,http://purl.obolibrary.org/obo/OBI_0001174,,,,,,,,,,,,,,,,,,,An administration in vivo to either actively or passively immunize an organism in order to induce a response against a specific immune epitope,,,,,,,epitope specific immune intervention,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001192,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific immune intervention,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Bjoern Peters, Randi Vita, Jason Greenbaum",,
http://purl.obolibrary.org/obo/OBI_0001784,ELISPOT assay measuring epitope specific monocyte chemotactic protein-1 production by T cells,CCL2/MCP-1 release|ELISPOT,An assay of epitope specific monocyte chemotactic protein-1 production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001465,,,,,,,,,,,,,,,,,,,An assay of epitope specific monocyte chemotactic protein-1 production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific monocyte chemotactic protein-1 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001784,,,,,,,,,,,,,,,,,,,,,,,,CCL2/MCP-1 release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific monocyte chemotactic protein-1 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001644,biological activity assay measuring epitope specific opsonization,opsonization|biological activity,A B cell epitope specific activation of additional immune response in vitro assay that detects opsonization.,false,,,http://purl.obolibrary.org/obo/OBI_0001704,,,,,,,,,,,,,,,,,,,A B cell epitope specific activation of additional immune response in vitro assay that detects opsonization.,IEDB,,,,,,biological activity assay measuring epitope specific opsonization,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001644,,,,,,,,,,,,,,,,,,,,,,,,opsonization|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific opsonization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/IAO_0000185,photograph,,"A photograph is created by projecting an image onto a photosensitive surface such as a chemically treated plate or film, CCD receptor, etc.",false,,,http://purl.obolibrary.org/obo/IAO_0000101,,,,,,,,,,,,,,,,,,,"A photograph is created by projecting an image onto a photosensitive surface such as a chemically treated plate or film, CCD receptor, etc.",WEB: http://en.wiktionary.org/wiki/photograph,,,,,,photograph,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000185,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,photograph,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Alan Ruttenberg|PERSON:Joanne Luciano|PERSON:Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0001264,biological activity assay measuring epitope specific transforming growth factor-beta production by T cells,TGFb release|biological activity,A T cell epitope specific cytokine production assay that detects transforming growth factor-beta production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects transforming growth factor-beta production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific transforming growth factor-beta production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001264,,,,,,,,,,,,,,,,,,,,,,,,TGFb release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific transforming growth factor-beta production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001529,data analysis service,,"A service in which a service consumer provides some input data and a service provider transforms, models, or interprets the input data and returns this generated data as output.",false,,,http://purl.obolibrary.org/obo/OBI_0001530,,,,,,,,,,,,,,,,,,,"A service in which a service consumer provides some input data and a service provider transforms, models, or interprets the input data and returns this generated data as output.",PERSON: Matthew Brush,,,,,,data analysis service,,"Statistaical analysis service, data visualization service",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,OBI:0001529,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,data analysis service,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Carlo Torniai|PERSON: Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_0000409,nucleic acid template role,,a reference substance role which inheres in nucleic acid material entity and is realized in the process of using the nucleic acid bearing the template role as a reference during synthesis of a reverse copy.,false,,,http://purl.obolibrary.org/obo/OBI_0000025,,,,,,,,,,,,,,,,,,,a reference substance role which inheres in nucleic acid material entity and is realized in the process of using the nucleic acid bearing the template role as a reference during synthesis of a reverse copy.,,,,,,,nucleic acid template role,,a model or standard for making comparisons; wordnet.princeton.edu/perl/webwn 19 feb 2009,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000409,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_33696,,,,,,,,,,,,,,,,,nucleic acid template role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0302884,extraction,,A material separation in which a desired component of an input material is separated from the remainder,false,,,http://purl.obolibrary.org/obo/OBI_0600014,,http://purl.obolibrary.org/obo/OBI_0000681,,,,,,,,,,,,,,,,,A material separation in which a desired component of an input material is separated from the remainder,,,,,,"Current the output of material processing defined as the molecular entity, main component in the output material entity, rather than the material entity that have grain molecular entity. 
'nucleic acid extract' is the output of 'nucleic acid extraction' and has grain 'nucleic acid'. However, the output of 'nucleic acid extraction' is 'nucleic acid' rather than 'nucleic acid extract'. We are aware of this issue and will work it out in the future.",extraction,,nucleic acid extraction using phenol chloroform,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302884,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,extraction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra|Person:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000798,capsule shell,,a small rounded gelatinous container,false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,,a small rounded gelatinous container,http://www.golovchenko.org/cgi-bin/wnsearch?q=capsule#2n,,,,,,capsule shell,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000798,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,capsule shell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_1110132,CD8 receptor,CD8,A transmembrane glycoprotein that serves as a co-receptor for the T cell receptor.,false,,,http://purl.obolibrary.org/obo/PR_000000001,,,,CD8,,,,,,,,,,,,,,,A transmembrane glycoprotein that serves as a co-receptor for the T cell receptor.,WEB: http://en.wikipedia.org/wiki/CD8,,,,,"This term does not belong in ONTIE.  It should be imported from PRO, but there seems to be no appropriate term as of 08/17/2009.",CD8 receptor,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000121,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110132,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD8 receptor,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/BFO_0000005,obsolete dependent continuant,,A continuant  that is either dependent on one or other independent continuant  bearers or inheres in or is borne by other entities.,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,A continuant  that is either dependent on one or other independent continuant  bearers or inheres in or is borne by other entities.,,,,,,,obsolete dependent continuant,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000005,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete dependent continuant,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001504,dissection,,"A planned process that separates and isolates tissues for surgical purposes, or for the analysis or study of their structures.",false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,"A planned process that separates and isolates tissues for surgical purposes, or for the analysis or study of their structures.",MO_374 dissect|EFO_0003856 dissection,,,,,,dissection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001504,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,dissection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/GO_0008150,biological_process,,"Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.",false,,,http://purl.obolibrary.org/obo/BFO_0000015,,,,,,,,,,,,,,,,,,,"Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.",,,,,,,biological_process,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0008150,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,biological_process,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/CARO_0000066,epithelium,,"Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina.",false,,,http://purl.obolibrary.org/obo/CARO_0000043,,,,,,,,,,,,,,,,,,,"Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina.",,,,,,,epithelium,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CARO:0000066,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/caro.owl,,,,,,,,,,,,,,,,,,,epithelium,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000233,obsolete_defined_material,,"Place holder class, Utility class to gather the defined classes",true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,"Place holder class, Utility class to gather the defined classes",OBI Biomaterial derived,,,,,false,obsolete_defined_material,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000121,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000226,,,,,,,,,,,,,,,,,,OBI:0000233,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_defined_material,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Susanna Sansone,,
http://purl.obolibrary.org/obo/OBI_1110085,antigen presentation function,APC,a function inhering in a cell  that expresses MHC molecules which is realized in the process of antigen processing and presentation of antigen derived parts by MHC molecules on the cell surface.,false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,APC,,,,,,,,,,,,,should add a reference to the antigen processing and presentation process.,,a function inhering in a cell  that expresses MHC molecules which is realized in the process of antigen processing and presentation of antigen derived parts by MHC molecules on the cell surface.,IEDB,,,,,,antigen presentation function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110085,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,antigen presentation function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/CL_0000794,"CD8-positive, alpha-beta cytotoxic T cell",,"A CD8-positive, alpha-beta T cell that is capable of killing target cells in an antigen specific manner with the phenotype perforin-positive and granzyme B-positive.",false,,,http://purl.obolibrary.org/obo/CL_0000625,,,,,,,,,,,,,,,,,,,"A CD8-positive, alpha-beta T cell that is capable of killing target cells in an antigen specific manner with the phenotype perforin-positive and granzyme B-positive.",,,,,,,"CD8-positive, alpha-beta cytotoxic T cell",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CL:0000794,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/cl.owl,,,,,,,,,,,,,,,,,,,"CD8-positive, alpha-beta cytotoxic T cell",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001034,environmental control device,,"An environmental control device is a device which has the function to control some aspect of the environment such as temperature, or humidity.",false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,"An environmental control device is a device which has the function to control some aspect of the environment such as temperature, or humidity.",OBI,,,,,,environmental control device,,A growth chamber is an environmental control device.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001034,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,environmental control device,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0000491,direct detection NMR probe,,An NMR probe designed to allow the direct detection of acquisition nuclei.,false,,,http://purl.obolibrary.org/obo/OBI_0000516,,,,,,,,,,,,,,,,,NMR device,,An NMR probe designed to allow the direct detection of acquisition nuclei.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400280,,,,,,direct detection NMR probe,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000491,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,direct detection NMR probe,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001153,genetic transformation objective,,a material transformation objective aims to create genetically modified organism or cell,false,,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,"suggested to be added by BP and AR during Oct 25, 2010 dev call",,a material transformation objective aims to create genetically modified organism or cell,Person: Jie Zheng,,,,,,genetic transformation objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001153,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,genetic transformation objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jie Zheng,,
http://purl.obolibrary.org/obo/CLO_0000031,cell line,,A cultured cell population that represents a genetically stable and homogenous population of cultured cells that shares a common propagation history (i.e. has been successively passaged together in culture). ,false,,,http://purl.obolibrary.org/obo/OBI_0001905,,,,,,,,,,,,,,,,,,,A cultured cell population that represents a genetically stable and homogenous population of cultured cells that shares a common propagation history (i.e. has been successively passaged together in culture). ,,,,,,,cell line,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CLO_0000001,,,,,,,,,,,,,,,,,,,,,,,,,,,CLO:0000031,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/clo.owl,,,,,,,,,,,,,,,,,,,cell line,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000906,induced hemagglutination,hemeagglutination,"The clumping or clustering of red blood cells caused by certain viruses, antibodies, or other substances",false,,,http://purl.obolibrary.org/obo/OBI_0000094,,,,hemeagglutination,,,,,,,,,,,,,,,"The clumping or clustering of red blood cells caused by certain viruses, antibodies, or other substances",WEB: http://medical-dictionary.thefreedictionary.com/hemagglutination,,,,,"MC, 20100217: This term was originally submitted to GO, see discussion at http://sourceforge.net/tracker/index.php?func=detail&aid=2947975&group_id=36855&atid=440764. After discussion it was agreed that this isn't a natural in vivo process and therefore out of scope for GO. 
Dev call Nov 22, 2010: To reflect this, the term's label has been updated to 'induced hemagglutination'.",induced hemagglutination,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CL_0000232,,,,OBI:0000906,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,induced hemagglutination,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person: Bjoern Peters|person: Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0001703,assay measuring qualitiative binding of a B cell epitope:antibody complex,qualitative binding|binding assay,A B cell epitope recognition assay that detects qualitative binding.,false,,,http://purl.obolibrary.org/obo/OBI_1110127|http://purl.obolibrary.org/obo/OBI_0001146,,,,,,,,,,,,,,,,,,,A B cell epitope recognition assay that detects qualitative binding.,IEDB,,,,,,assay measuring qualitiative binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001703,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|binding assay,,,,,,,,,,,,,,,,,,,,,,assay measuring qualitiative binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001597,cell bound MHC competitive binding assay measuring half maximal inhibitory concentration [IC50] of a MHC:ligand complex using T cell epitope recognition,half maximal inhibitory concentration (IC50)|cellular MHC/T cell inhibition|nM,A cell bound MHC ligand binding half maximal inhibitory concentration (IC50) determination assay that uses a T cell epitope recognition assay to measure ligand binding.,false,,,http://purl.obolibrary.org/obo/OBI_0001992,,,,,,,,,,,,,,,,,,,A cell bound MHC ligand binding half maximal inhibitory concentration (IC50) determination assay that uses a T cell epitope recognition assay to measure ligand binding.,IEDB,,,,,,cell bound MHC competitive binding assay measuring half maximal inhibitory concentration [IC50] of a MHC:ligand complex using T cell epitope recognition,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001597,,,,,,,,,,,,,,,,,,,,,,,,half maximal inhibitory concentration (IC50)|cellular MHC/T cell inhibition|nM,,,,,,,,,,,,,,,,,,,,,,cell bound MHC competitive binding assay measuring half maximal inhibitory concentration [IC50] of a MHC:ligand complex using T cell epitope recognition,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001240,intracellular cytokine staining assay measuring epitope specific interleukin-6 production by T cells,IL-6 release|ICS,An assay of epitope specific interleukin-6 production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001451,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-6 production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-6 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001240,,,,,,,,,,,,,,,,,,,,,,,,IL-6 release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-6 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001292,biological activity assay measuring epitope specific interleukin-15 production by T cells,IL-15 release|biological activity,A T cell epitope specific cytokine production assay that detects interleukin-15 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects interleukin-15 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific interleukin-15 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001292,,,,,,,,,,,,,,,,,,,,,,,,IL-15 release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific interleukin-15 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000721,glucose tolerance test,,"is a process in  which following administration of a bolus a glucose in-vivo, glucose clearance from blood plasma is monitored over time by repeated glucose measurement in blood serum. the output of a process is a measure which can be used to evaluate the severity of insulin resistance or the efficiency of glucose clearance.",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,http://purl.obolibrary.org/obo/OBI_0000441|http://purl.obolibrary.org/obo/OBI_0000015,,,,,,,,,,,,,,,,,"is a process in  which following administration of a bolus a glucose in-vivo, glucose clearance from blood plasma is monitored over time by repeated glucose measurement in blood serum. the output of a process is a measure which can be used to evaluate the severity of insulin resistance or the efficiency of glucose clearance.",NuGO OBI plan branch,,,,,"30-10-2013:[author: PRS] removing ""realizes some (concretizes some 'time series design')"" axiom as it causes 'gtt' to be classified under study design execution instead of assay",glucose tolerance test,,"PMID: 19527607
Using the 100-g Oral Glucose Tolerance Test to Predict Fetal and Maternal Outcomes in Women with Gestational Diabetes Mellitus.
Lin CH, Wen SF, Wu YH, Huang MJ.
Chang Gung Med J. 2009 May-Jun;32(3):283-9.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000721,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,glucose tolerance test,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0002016,histone modification identification by ChIP-chip assay,histone modification ChIP-chip,A ChIP-chip assay to identify regions containing specific histones and their modifications.,false,,,http://purl.obolibrary.org/obo/OBI_0001248|http://purl.obolibrary.org/obo/OBI_0002020,,http://purl.obolibrary.org/obo/OBI_0001234,,histone modification ChIP-chip,,,,,,,,,,,,,,,A ChIP-chip assay to identify regions containing specific histones and their modifications.,Penn group,,,,,,histone modification identification by ChIP-chip assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002016,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,histone modification identification by ChIP-chip assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Beta Cell Biology Consoritum,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000748,bisulfite sequencing,,An assay which allows to determine the methylation status of genomic DNA using DNA sequencing techniques preceded by a bisulfite based chemical modification of genomic DNA at CpG island location.,false,,,http://purl.obolibrary.org/obo/OBI_0001266|http://purl.obolibrary.org/obo/OBI_0000626,,http://purl.obolibrary.org/obo/OBI_0001234,,,,,,,,,,,,,,,,,An assay which allows to determine the methylation status of genomic DNA using DNA sequencing techniques preceded by a bisulfite based chemical modification of genomic DNA at CpG island location.,adapted from Wikipedia,,,,,"8/19/09: Chris says that there may used to be a way of doing bisulfite sequencing comparing lengths of restriction fragments, which implies that it is possible to do without DNA sequencing.",bisulfite sequencing,,"PMID: 19581485. High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing. Hodges E, Smith A, Kendall J, Xuan Z, Ravi K, Rooks M, Zhang M, Ye K, Battacharjee A, Brizuela L, McCombie WR, Wigler M, Hannon GJ, Hicks J.
Genome Res. 2009 Jul 6.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000626,http://purl.obolibrary.org/obo/OBI_0400103,,,,,,,,,,,,,,,OBI:0000748,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,bisulfite sequencing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000530,Bruker UltraShield Plus NMR magnet,,"An NMR magnet of which Brukers claims it is the latest and most advanced self-shielding NMR magnet technology ever developed. These magnets are the ultimate advancement in high performance, actively-shielded NMR solutions. They offer unprecedented shielding performance whilst ensuring no compromise in system homogeneity, stability or cryogenic specifications.",false,,,http://purl.obolibrary.org/obo/OBI_0000597,,,,,,,,,,,,,,,,,NMR instrument,,"An NMR magnet of which Brukers claims it is the latest and most advanced self-shielding NMR magnet technology ever developed. These magnets are the ultimate advancement in high performance, actively-shielded NMR solutions. They offer unprecedented shielding performance whilst ensuring no compromise in system homogeneity, stability or cryogenic specifications.",WEB:<http://www.bruker-biospin.com/nmr_magnets_usplus.html>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400190,,,,,,Bruker UltraShield Plus NMR magnet,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000530,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker UltraShield Plus NMR magnet,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000453,measure function,,Measure function is a function that is borne by a processed material  and realized in a process in which information about some entity is expressed relative to some reference.,false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,Measure function is a function that is borne by a processed material  and realized in a process in which information about some entity is expressed relative to some reference.,,,,,,,measure function,,"A glucometer measures blood glucose concentration, the glucometer has a measure function.",,,,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,measure function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot|PERSON: Daniel Schober|PERSON:Frank Gibson|PERSON: Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0002010,Human 3x720K Whole Genome CGH Tiling Array,Nimblegen Human 3x720K Whole Genome CGH Tiling Array,"A tiling array which is manufactured by the Nimblegen corporation. Built to analyze DNA sequence copy number by comparative genomic hybridization for human DNA against 3x720,000 features.",false,,,http://purl.obolibrary.org/obo/OBI_0001307,,,,Nimblegen Human 3x720K Whole Genome CGH Tiling Array,,,,,,,,,,,,,,,"A tiling array which is manufactured by the Nimblegen corporation. Built to analyze DNA sequence copy number by comparative genomic hybridization for human DNA against 3x720,000 features.",http://www.nimblegen.com/downloads/support/05434483001_NG_CGHLOH_UGuide_v9p1.pdf,,,,,,Human 3x720K Whole Genome CGH Tiling Array,,Deletion in Xp22.11: PTCHD1 is a candidate gene for X-linked intellectual disability with or without autism PMID:21091464,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002010,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Human 3x720K Whole Genome CGH Tiling Array,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"PERSON: Venkat Malladi, Chris Stoeckert, Jie Zheng, Alan Ruttenberg",,
http://purl.obolibrary.org/obo/OBI_0001436,biological activity assay measuring epitope specific granzyme B release by T cells,granzyme B release|biological activity,A T cell epitope specific cytotoxic T cell degranulation assay that detects granzyme B release by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_0001269,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytotoxic T cell degranulation assay that detects granzyme B release by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific granzyme B release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001436,,,,,,,,,,,,,,,,,,,,,,,,granzyme B release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific granzyme B release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001879,reagent,,"A biological or chemical entity that bears a reagent role in virtue of it being intended for application in a scientific technique  to participate in (or have molecular parts that participate in) a chemical reaction that facilitates the generation of data about some distinct entity, or the generation of some distinct material specified output.|(copied from ReO)
Reagents are distinguished from devices/instruments that also serve as facilitators in scientific techniques by the fact that reagents are chemical or biological in nature and necessarily participate in or have parts that participate in some chemical interaction or reaction during their intended participation in some technique.  By contrast, devices do not participate in a chemical reaction/interaction during the technique.

Reagents are distinguished from study subjects/evaluants in that study subjects and evaluants are that about which conclusions are drawn and knowledge is sought in an investigation - while reagents, by definition, are not.  It should be noted, however, that reagent and study subject/evaluant roles can be borne by instances of the same type of material entity - but a given instance can only realize one of these roles in the execution of a given  assay. For example, taq polymerase can bear a reagent role or an evaluant role.  In a DNA sequencing assay aimed at generating sequence data about some plasmid, the reagent role of the taq polymerase is realized. In an assay to evaluate the quality of the taq polymerase itself, the evaluant/study subject role of the taq is realized, but not the reagent role since the taq is the subject about which data is generated.

In regard to the statement that reagents are 'distinct' from the specified outputs of a technique:  note that a reagent may be incorporated into a material output of a technique, as long as the IDENTITY of this output is distinct from that of the bearer of the reagent role.  For example, dNTPs input into a PCR are reagents that become part of the material output of this technique, but this output has a new identity (ie that of a 'nucleic acid molecule') that is distinct from the identity of the dNTPs that comprise it.  Similarly, a biotin molecule input into a cell labeling technique are reagents that become part of the specified output, but the identity of the output is that of some modified cell specimen which shares identity with the input unmodified cell specimen, and not with the biotin label. Thus, we see that an important criteria of 'reagent-ness' is that it is a facilitator, and not the primary focus of an investigation or material processing technique (ie not the specified subject/evaluant about which knowledge is sought, or the specified output material of the technique).",false,,,http://purl.obolibrary.org/obo/OBI_0000047|http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,"A biological or chemical entity that bears a reagent role in virtue of it being intended for application in a scientific technique  to participate in (or have molecular parts that participate in) a chemical reaction that facilitates the generation of data about some distinct entity, or the generation of some distinct material specified output.",PERSON:Matthew Brush,,,,,"2013-6-5 MHB: Clarifications regarding the distinction between reagetns and devices were made at the May 2013 Philly Workshop. Reagents are distinguished from devices that also participate in scientific techniques by the fact that reagents are chemical or biological in nature and necessarily participate in some chemical interaction or reaction during the realization of their experimental role. By contrast, devices do not participate in such chemical reactions/interactions.  Note that there are cases where devices use reagent components during their operation, where the reagent-device distinction is less clear.  For examples, see editor note on OBI:device.",reagent,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001879,,,,,,,,,,,,,,,,,,"(copied from ReO)
Reagents are distinguished from devices/instruments that also serve as facilitators in scientific techniques by the fact that reagents are chemical or biological in nature and necessarily participate in or have parts that participate in some chemical interaction or reaction during their intended participation in some technique.  By contrast, devices do not participate in a chemical reaction/interaction during the technique.

Reagents are distinguished from study subjects/evaluants in that study subjects and evaluants are that about which conclusions are drawn and knowledge is sought in an investigation - while reagents, by definition, are not.  It should be noted, however, that reagent and study subject/evaluant roles can be borne by instances of the same type of material entity - but a given instance can only realize one of these roles in the execution of a given  assay. For example, taq polymerase can bear a reagent role or an evaluant role.  In a DNA sequencing assay aimed at generating sequence data about some plasmid, the reagent role of the taq polymerase is realized. In an assay to evaluate the quality of the taq polymerase itself, the evaluant/study subject role of the taq is realized, but not the reagent role since the taq is the subject about which data is generated.

In regard to the statement that reagents are 'distinct' from the specified outputs of a technique:  note that a reagent may be incorporated into a material output of a technique, as long as the IDENTITY of this output is distinct from that of the bearer of the reagent role.  For example, dNTPs input into a PCR are reagents that become part of the material output of this technique, but this output has a new identity (ie that of a 'nucleic acid molecule') that is distinct from the identity of the dNTPs that comprise it.  Similarly, a biotin molecule input into a cell labeling technique are reagents that become part of the specified output, but the identity of the output is that of some modified cell specimen which shares identity with the input unmodified cell specimen, and not with the biotin label. Thus, we see that an important criteria of 'reagent-ness' is that it is a facilitator, and not the primary focus of an investigation or material processing technique (ie not the specified subject/evaluant about which knowledge is sought, or the specified output material of the technique).",,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000094,,,reagent,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_0000205,obsolete_dropout role,,Dropout is a study subject role borne by an entity realized by a process of leaving the study earlier than the protocol specified and where the bearer of the dropout role had been borne study subject role prior to bearing dropout role.,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,Dropout is a study subject role borne by an entity realized by a process of leaving the study earlier than the protocol specified and where the bearer of the dropout role had been borne study subject role prior to bearing dropout role.,OBI,,,,,"Will be modelled as defined material, ouput of some 'dropout or withdrawal
process' instead of role",obsolete_dropout role,,Escaped rat; human who moved to another city. Rat which escapes part way through a study; a human study participant who moved to another city before the study was completed (and stopped participating in the study),,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,OBI:0000205,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_dropout role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Role Branch,,
http://purl.obolibrary.org/obo/CARO_0000004,portion of organism substance,,"Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body.",false,,,http://purl.obolibrary.org/obo/CARO_0001008,,,,,,,,,,,,,,,,,,,"Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body.",,,,,,,portion of organism substance,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CARO:0000004,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/caro.owl,,,,,,,,,,,,,,,,,,,portion of organism substance,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001030,RNASE T1 structure mapping assay,single nucleotide resolution mapping assay using RNAse T1,a single-nucleotide-resolution ribonucleic acid structure mapping assay which uses RNAse T1 as reagent and enzymatic probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,false,,,http://purl.obolibrary.org/obo/OBI_0001014,,http://purl.obolibrary.org/obo/OBI_0000441,,single nucleotide resolution mapping assay using RNAse T1,,,,,,,,,,,,,,,a single-nucleotide-resolution ribonucleic acid structure mapping assay which uses RNAse T1 as reagent and enzymatic probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,RNA ontology,,,,,,RNASE T1 structure mapping assay,,PMID:114514,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_33697,,,,OBI:0001030,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,RNASE T1 structure mapping assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000102,responsible party role,responsible party,a study personnel role played by a party who is accountable for the execution of a study component and can make decisions about the conduct of the study,false,,,http://purl.obolibrary.org/obo/OBI_0000202,,,,responsible party,,,,,,,,,,,,,,,a study personnel role played by a party who is accountable for the execution of a study component and can make decisions about the conduct of the study,OBI,,,,,,responsible party role,,he THERAPIST has the ability to print a separate statement for the patient and each responsible party. http://www.beaverlog.com/therapist/ez_support/billing/responsible_party_statements.htm,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000102,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,responsible party role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0000939,training process,,a process that achieves a training objective,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,,,a process that achieves a training objective,,,,,,,training process,,"e.g. a training course run by a vendor on their instrument, a training service on a assay by a core facility",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000939,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,training process,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000455,consume data function,,Process data function is a function that is borne by in a material entity by virtue of its structure. When realized the material entity consumes data.,false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,Process data function is a function that is borne by in a material entity by virtue of its structure. When realized the material entity consumes data.,,,,,,,consume data function,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000455,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,consume data function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot|PERSON: Daniel Schober|PERSON: Frank Gibson,,
http://purl.obolibrary.org/obo/OBI_0400026,CyFlow Space,,"A CyFlow_Space is a flow_cytometer_sorter manufactured by Partec. Its specs are: 8optical parameters, 6 colours:FSC, SSC, FL1-FL6 , 3laser light sources: 200mW@488nm blue solid state laser 25mW@635nm red diode laser 50mW@405nm violet or 8mW@375nm ultraviolet diode laser _ultracompact desktop high end instrument. Parallel 16bit digital pulse processing. The CyFlow Space is a 6-Colour FCM System and Cell Sorter for Clinical Routine and Research.",false,,,http://purl.obolibrary.org/obo/OBI_0400099,,,,,,,,,,,,,,,,,,,"A CyFlow_Space is a flow_cytometer_sorter manufactured by Partec. Its specs are: 8optical parameters, 6 colours:FSC, SSC, FL1-FL6 , 3laser light sources: 200mW@488nm blue solid state laser 25mW@635nm red diode laser 50mW@405nm violet or 8mW@375nm ultraviolet diode laser _ultracompact desktop high end instrument. Parallel 16bit digital pulse processing. The CyFlow Space is a 6-Colour FCM System and Cell Sorter for Clinical Routine and Research.",http://www.partec.de/products/cyflowspace.html,,,,,,CyFlow Space,,CyFlow Space at TSRI Flow Cytometry Core Facility,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400026,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CyFlow Space,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0500023,compliance rule,,a compliance rule is a rule which ensures a compliance process occurs,false,,,http://purl.obolibrary.org/obo/IAO_0000055,,,,,,,,,,,,,,,,,,,a compliance rule is a rule which ensures a compliance process occurs,PRS,,,,,,compliance rule,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500023,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,compliance rule,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PRS,,
http://purl.obolibrary.org/obo/OBI_1110023,immunogen,,a material entity bearing the immunogen role,false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,a material entity bearing the immunogen role,IEDB,,,,,,immunogen,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110023,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,immunogen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0002040,chromatin isolation by RNA purification sequencing assay,ChIRP-seq assay|Chromatin Isolation by RNA purification|ChIRP-seq,A detection of specific nucleic acids with complementary probes to discover regions of the genome which are bound by a specific RNA (or a by a ribonucleoprotein containing the RNA of interest) using high-throughput sequencing.,false,,,http://purl.obolibrary.org/obo/OBI_0000874,,,,ChIRP-seq assay|Chromatin Isolation by RNA purification|ChIRP-seq,,,,,,,,,,,,,,,A detection of specific nucleic acids with complementary probes to discover regions of the genome which are bound by a specific RNA (or a by a ribonucleoprotein containing the RNA of interest) using high-throughput sequencing.,"Chu et al. (31 August 2011). ""Genomic Maps of Long Noncoding RNA Occupancy Reveal Principles of RNA-Chromatin Interactions"". Molecular Cell.",,,,,,chromatin isolation by RNA purification sequencing assay,,"Csorba et al., (November 2014). ""Antisense COOLAIR mediates the coordinated switching of chromatin states at FLC during vernalization."" Proc Natl Acad Sci 111(45):16160-5. doi: 10.1073/pnas.1419030111.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002040,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,chromatin isolation by RNA purification sequencing assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0400067,long pass filter,,A long pass filter is an optical filter that passes high wavelengths of light but attenuates (or reduces) wavelengths lower than the cutoff frequency. A long pass filter with a cutoff of 500 nm would pass all wavelengths greater than 500 nm.,false,,,http://purl.obolibrary.org/obo/OBI_0400079,,,,,,,,,,,,,,,,,,,A long pass filter is an optical filter that passes high wavelengths of light but attenuates (or reduces) wavelengths lower than the cutoff frequency. A long pass filter with a cutoff of 500 nm would pass all wavelengths greater than 500 nm.,http://en.wikipedia.org/wiki/high-pass_filter,,,,,,long pass filter,,750 LP filter,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400067,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,long pass filter,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0000675,statistical hypothesis test objective,hypothesis test objective,is a data transformation objective where the aim is to estimate statistical significance with the aim of proving or disproving a hypothesis by means of some data transformation ,false,,,http://purl.obolibrary.org/obo/OBI_0200166,,,,hypothesis test objective,,,,,,,,,,,,,,,is a data transformation objective where the aim is to estimate statistical significance with the aim of proving or disproving a hypothesis by means of some data transformation ,WEB:  http://en.wikipedia.org/wiki/Statistical_hypothesis_testing,,,,,,statistical hypothesis test objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000675,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,statistical hypothesis test objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Person:Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0600003,performing a clinical assessment,clinical diagnosis,"a protocol application during which a series of tests are made of a patient  leading to determination of disease state, or condition.",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,http://purl.obolibrary.org/obo/OBI_0000441,,clinical diagnosis,,,,,,,,,,,,,(maybe CIO),,"a protocol application during which a series of tests are made of a patient  leading to determination of disease state, or condition.",OBI branch derived,,,,,,performing a clinical assessment,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000988,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000075,,,OBI:0600003,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,performing a clinical assessment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0001764,cytometric bead array assay measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells,CCL4/MIP-1b release|cytometric bead array,An assay of epitope specific chemokine (C-C motif) ligand 4 production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001345,,,,,,,,,,,,,,,,,,,An assay of epitope specific chemokine (C-C motif) ligand 4 production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001764,,,,,,,,,,,,,,,,,,,,,,,,CCL4/MIP-1b release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000558,Varian UNITY INOVA spectrometer,,"The UNITY INOVA is also the easiest spectrometer to use and is also the choice of those interested in using advanced NMR techniques in their own research, but without becoming, or hiring, an NMR expert. A complete set of turnkey operating environments is available for the UNITY INOVA covering the structure and dynamics of biological macromolecules, small molecules, solids, and imaging. These packages put the combined NMR expertise of the entire Varian NMR community at your fingertips.",false,,,http://purl.obolibrary.org/obo/OBI_0000611,,,,,,,,,,,,,,,,,NMR instrument,,"The UNITY INOVA is also the easiest spectrometer to use and is also the choice of those interested in using advanced NMR techniques in their own research, but without becoming, or hiring, an NMR expert. A complete set of turnkey operating environments is available for the UNITY INOVA covering the structure and dynamics of biological macromolecules, small molecules, solids, and imaging. These packages put the combined NMR expertise of the entire Varian NMR community at your fingertips.",WEB:<http://www.varianinc.com/cgi-bin/nav?products/NMR/spectromet/inova/index&cid=HFIH>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400236,,,,,,Varian UNITY INOVA spectrometer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000558,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Varian UNITY INOVA spectrometer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001706,assay measuring B cell epitope specific biological activity,biological activity|any method,A B cell epitope recognition assay that detects biological activity.,false,,,http://purl.obolibrary.org/obo/OBI_1110127,,,,,,,,,,,,,,,,,,,A B cell epitope recognition assay that detects biological activity.,IEDB,,,,,,assay measuring B cell epitope specific biological activity,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001706,,,,,,,,,,,,,,,,,,,,,,,,biological activity|any method,,,,,,,,,,,,,,,,,,,,,,assay measuring B cell epitope specific biological activity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0400005,A10-Analyzer,,"A A10 is a flow_cytometer_analyser manufactured by Apogee. It uses an arc lamp as a light source, with choices of 75W Xe, 75W Xe/Hg or 100W Hg arc lamps. It has filters and collectors for up to three fluorescent parameters and two scatter parameters. It uses analog electronics. The A10 can be used for measuring the properties of individual cells.",false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,,,,,,,,,,,,,,,,"A A10 is a flow_cytometer_analyser manufactured by Apogee. It uses an arc lamp as a light source, with choices of 75W Xe, 75W Xe/Hg or 100W Hg arc lamps. It has filters and collectors for up to three fluorescent parameters and two scatter parameters. It uses analog electronics. The A10 can be used for measuring the properties of individual cells.",http://www.apogeeflow.com/flow_cytometry_products.htm,,,,,,A10-Analyzer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400005,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,A10-Analyzer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0000318,eluate,eluted material,"a eluate is a material entity which results from an elution, e.g. from a chromatography column. it has as part a material entity with role mobile phase",false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,eluted material,,,,,,,,,,,,,,,"a eluate is a material entity which results from an elution, e.g. from a chromatography column. it has as part a material entity with role mobile phase",OBI Bionaterial,,,,,"need to add restriction to indicate: has_part some (material entity has_role mobile phase)
need to add mobile phase as role",eluate,,Raman spectroscopic detection of haemoproteins in the eluate from high-performance liquid chromatography. J Chromatogr. 1983 Jan 7;254:285-8. PMID: 6298263,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000318,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0302905,,,eluate,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001512,cytometric bead array assay measuring epitope specific interleukin-17A production by T cells,IL-17A release|cytometric bead array,A T cell epitope specific interleukin-17A production assay that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001773|http://purl.obolibrary.org/obo/OBI_0001296,,,,,,,,,,,,,,,,,,,A T cell epitope specific interleukin-17A production assay that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific interleukin-17A production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001512,,,,,,,,,,,,,,,,,,,,,,,,IL-17A release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific interleukin-17A production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_1110168,ELISPOT assay measuring epitope specific tumor necrosis factor production by T cells,TNFa release|ELISPOT,A T cell epitope specific tumor necrosis factor production assay that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001416|http://purl.obolibrary.org/obo/OBI_0001272,,,,,,,,,,,,,,,,,,,A T cell epitope specific tumor necrosis factor production assay that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific tumor necrosis factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110168,,,,,,,,,,,,,,,,,,,,,,,,TNFa release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific tumor necrosis factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000272,protocol,study protocol,"A plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process.",false,,,http://purl.obolibrary.org/obo/IAO_0000104,,,,,,,,,,,,,,,,,,,"A plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process.",OBI branch derived + wikipedia (http://en.wikipedia.org/wiki/Protocol_%28natural_sciences%29),,,,,,protocol,,"PCR protocol, has objective specification, amplify DNA fragment of interest, and has action specification describes the amounts of experimental reagents used (e..g. buffers, dNTPS, enzyme), and the temperature and cycle time settings for running the PCR.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000272,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,study protocol,protocol,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0002060,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-C motif) ligand 17 production by T cells,CCL17/TARC release|RNA/DNA detection,An assay of epitope specific chemokine (C-C motif) ligand 17 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0002056,,,,,,,,,,,,,,,,,,,An assay of epitope specific chemokine (C-C motif) ligand 17 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-C motif) ligand 17 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002060,,,,,,,,,,,,,,,,,,,,,,,,CCL17/TARC release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-C motif) ligand 17 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001018,Rhodium DNA structure mapping assay,single nucleotide resolution mapping assay using Rhodium probe,a single-nucleotide-resolution nucleic acid structure mapping assay which uses Rhodium as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,false,,,http://purl.obolibrary.org/obo/OBI_0001017,,http://purl.obolibrary.org/obo/OBI_0000441,,single nucleotide resolution mapping assay using Rhodium probe,,,,,,,,,,,,,,,a single-nucleotide-resolution nucleic acid structure mapping assay which uses Rhodium as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,RNA ontology,,,,,,Rhodium DNA structure mapping assay,,PMID:2843807,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001018,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Rhodium DNA structure mapping assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0200201,ANOVA,,ANOVA or analysis of variance is a data transformation in which a statistical test of whether the means of several groups are all equal.,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,ANOVA or analysis of variance is a data transformation in which a statistical test of whether the means of several groups are all equal.,,,,,,,ANOVA,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200201,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ANOVA,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0001981,disease exacerbation in vivo intervention experiment,,An in vivo intervention experiment that tests the ability of the intervention to increase the severity of a disease in the host.,false,,,http://purl.obolibrary.org/obo/OBI_0001980,,,,,,,,,,,,,,,,,,,An in vivo intervention experiment that tests the ability of the intervention to increase the severity of a disease in the host.,IEDB,,,,,Should have data about disease severity as readout; could just use disease for now,disease exacerbation in vivo intervention experiment,,Injecting a set of mice with a peptide and measuring symtoms to determine if their disease course was more severe than the disease course of a set of mice that were not injected with the same peptide.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001981,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,disease exacerbation in vivo intervention experiment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000905,sequence feature annotation,,Information about a sequence region|place holder for sequence ontology term,false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,,,,,,,,,,,,,,,,Information about a sequence region,Bjoern Peters,,,,,,sequence feature annotation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000905,,,,,,,,,,,,,,,,,,place holder for sequence ontology term,,,,,,,,,,,,,,,,,,,,,,,,,,,,sequence feature annotation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001842,ELISPOT assay measuring epitope specific interleukin-1 beta production by T cells,IL-1b release|ELISPOT,An assay of epitope specific interleukin-1 beta production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001449,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-1 beta production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific interleukin-1 beta production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001842,,,,,,,,,,,,,,,,,,,,,,,,IL-1b release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific interleukin-1 beta production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000938,categorical measurement datum,nominal mesurement datum,A measurement datum that is reported on a categorical scale,false,,,http://purl.obolibrary.org/obo/IAO_0000109,,,,nominal mesurement datum,,,,,,,,,,,,,,,A measurement datum that is reported on a categorical scale,"Bjoern Peters
",,,,,,categorical measurement datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001930,,,,,,,,,OBI:0000938,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,categorical measurement datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001076,incubator shaker,,"An incubating device that provides shaking motion for biomedical applications (e.g., cell cultures).",false,,,http://purl.obolibrary.org/obo/OBI_0000967|http://purl.obolibrary.org/obo/OBI_0001034,,,,,,,,,,,,,,,,,,,"An incubating device that provides shaking motion for biomedical applications (e.g., cell cultures).",PERSON: Erik Segerdell,,,,,,incubator shaker,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000370|http://purl.obolibrary.org/obo/OBI_0000379|http://purl.obolibrary.org/obo/OBI_0000401,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001076,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,incubator shaker,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0002057,biological activity assay measuring epitope specific macrophage migration inhibitory factor (MIF) production by T cells,MIF release|biological activity,A T cell epitope specific cytokine production assay that detects macrophage migration inhibitory factor (MIF) production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects macrophage migration inhibitory factor (MIF) production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific macrophage migration inhibitory factor (MIF) production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002057,,,,,,,,,,,,,,,,,,,,,,,,MIF release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific macrophage migration inhibitory factor (MIF) production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/GO_0040030,"regulation of molecular function, epigenetic",,"Any heritable epigenetic process that modulates the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya.",false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,"Any heritable epigenetic process that modulates the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya.",,,,,,,"regulation of molecular function, epigenetic",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0040030,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,"regulation of molecular function, epigenetic",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_1110190,epitope specific IL-12 release by T cells,,A biological process where T cells produce IL-12 resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/OBI_0001193|http://purl.obolibrary.org/obo/GO_0032615,,,,,,,,,,,,,,,,,,,A biological process where T cells produce IL-12 resulting from the recognition of a T cell epitope.,IEDB,,,,,,epitope specific IL-12 release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110190,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific IL-12 release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0200007,box-cox transformation,,"A box-cox transformation is a data transformation according to the methods of Box and Cox as described in the article Box, G. E. P. and Cox, D.R. (1964) An analysis of transformations. Journal of Royal Statistical Society, Series B, vol. 26, pp. 211-246.",false,,,http://purl.obolibrary.org/obo/OBI_0200169,,http://purl.obolibrary.org/obo/OBI_0200167,,,,,,,,,,,,,,,,,"A box-cox transformation is a data transformation according to the methods of Box and Cox as described in the article Box, G. E. P. and Cox, D.R. (1964) An analysis of transformations. Journal of Royal Statistical Society, Series B, vol. 26, pp. 211-246.","ARTICLE: Box, G. E. P. and Cox, D.R. (1964), ""An analysis of transformations"", Journal of Royal Statistical Society, Series B, vol. 26, pp. 211-246.",,,,,,box-cox transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200007,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,box-cox transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Ryan Brinkman,,
http://purl.obolibrary.org/obo/OBI_0000918,Dulbecco's modified Eagle medium,D-MEM|DMEM,"A culture medium containing iron, phenol red, amino acids, salts, glucose and vitamins.",false,,,http://purl.obolibrary.org/obo/OBI_0000079,,,,D-MEM|DMEM,,,,,,,,,,,,,,,"A culture medium containing iron, phenol red, amino acids, salts, glucose and vitamins.",,,,,,Logical definition should contain all components listed in textual definition at some point.,Dulbecco's modified Eagle medium,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000918,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Dulbecco's modified Eagle medium,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Bjoern Peters,,
http://purl.obolibrary.org/obo/BFO_0000028,three-dimensional spatial region,,,false,,,http://purl.obolibrary.org/obo/BFO_0000006,,,,,,,ThreeDimensionalSpatialRegion,3d-s-region,,,,,,,,,,,,,,,,,,three-dimensional spatial region,A three-dimensional spatial region is a spatial region that is of three dimensions. (axiom label in BFO2 Reference: [040-001]),"a sphere-shaped region of space,|a cube-shaped region of space",,,,,,,,(forall (x) (if (ThreeDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [040-001] ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000028,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,three-dimensional spatial region,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000731,recombinant vector,,"A recombinant vector is created by a recombinant vector cloning process, and contains nucleic acids that can be amplified. It retains functions of the original cloning vector.",false,,,http://purl.obolibrary.org/obo/OBI_0000047|http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,"A recombinant vector is created by a recombinant vector cloning process, and contains nucleic acids that can be amplified. It retains functions of the original cloning vector.",,,,,,,recombinant vector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000731,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,recombinant vector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_1110114,contact to pathogen carrying biological vector,,a process in which a vector carrying an infectious agent comes close enough to a potential host organism that a contact can result,false,,,http://purl.obolibrary.org/obo/OBI_1110111,,,,,,,,,,,,,,,,,,,a process in which a vector carrying an infectious agent comes close enough to a potential host organism that a contact can result,IEDB,,,,,,contact to pathogen carrying biological vector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110114,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,contact to pathogen carrying biological vector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000716,ChIP-seq assay,chromatin immunoprecipitation sequencing assay,"an assay which aims at identifying protein binding sites in genomic DNA and determining how protein may regulate gene transcription by relying on immunoprecipitation of DNA bound protein, creation of a library of corresponding DNA fragments  (either single or paired-end fragments) and subsequent sequencing using parallelized sequencing methods.",false,,,http://purl.obolibrary.org/obo/OBI_0600047|http://purl.obolibrary.org/obo/OBI_0002020|http://purl.obolibrary.org/obo/OBI_0001956,,http://purl.obolibrary.org/obo/OBI_0001234|http://purl.obolibrary.org/obo/OBI_0001398,,chromatin immunoprecipitation sequencing assay,,,,,,,,,,,,,"made some modification based on the discussion on 2011/4/4 obi dev call, using DNA sequencing instead of union of some specific DNA sequencing processes",,"an assay which aims at identifying protein binding sites in genomic DNA and determining how protein may regulate gene transcription by relying on immunoprecipitation of DNA bound protein, creation of a library of corresponding DNA fragments  (either single or paired-end fragments) and subsequent sequencing using parallelized sequencing methods.",adapted from Wikipedia,,,,,,ChIP-seq assay,,"PMID: 19275939
ChIP-seq: using high-throughput sequencing to discover protein-DNA interactions.
Schmidt D, Wilson MD, Spyrou C, Brown GD, Hadfield J, Odom DT.
Methods. 2009 Jul;48(3):240-8. Epub 2009 Mar 9.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000690|http://purl.obolibrary.org/obo/OBI_0000711|http://purl.obolibrary.org/obo/OBI_0000626,http://purl.obolibrary.org/obo/OBI_0400103,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001573,,,OBI:0000716,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ChIP-seq assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/IAO_0000088,report,,"a document assembled by an author for the purpose of providing information for the audience. A report is the output of a documenting process and has the objective to be consumed by a specific audience. Topic of the report is on something that has completed. A report is not a single figure. Examples of reports are journal article, patent application, grant progress report, case report (not patient record)",false,,,http://purl.obolibrary.org/obo/IAO_0000310,,,,,,,,,,,,,,,,,,,"a document assembled by an author for the purpose of providing information for the audience. A report is the output of a documenting process and has the objective to be consumed by a specific audience. Topic of the report is on something that has completed. A report is not a single figure. Examples of reports are journal article, patent application, grant progress report, case report (not patient record)",OBI_0000099|GROUP: OBI,,,,,"2009-03-16: work has been done on this term during during the OBI workshop winter 2009 and the current definition was considered acceptable for use in OBI. If there is a need to modify this definition please notify OBI.|2009-03-16: this was report of results with definition: A report is a narrative object that is a formal statement of the results of an investigation, or of any matter on which definite information is required, made by some person or body instructed or required to do so.|2009-08-10 Alan Ruttenberg: Larry Hunter suggests that this be obsoleted and replaced by 'document'. Alan restored as there are OBI dependencies and this merits further discussion|2009-03-16: comment from Darren Natale: I am slightly uneasy with the sentence ""Topic of the report is on 
something that has completed.""  Should it be restricted to those things 
that are completed?  For example, a progress report is (usually) about 
something that definitely has *not* been completed, or may include 
(only) projections.  I think the definition would not suffer if the 
whole sentence is deleted.|disagreement about where reports go. alan: only some gene lists are reports. Is a report all the content of some document? The example of usage suggests that a report may be part of  some article. Term needs clarification",report,,Examples of reports are gene lists and investigation reports. These are not published (journal) articles but may be included in a journal article.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000088,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,report,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot|PERSON: Alan Ruttenberg|PERSON:Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0001205,cell component comparison design,,A study design that compares samples from different cell components.,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,A study design that compares samples from different cell components.,MO_1019 cell_component_comparison_design,,,,,,cell component comparison design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000219,,,,,,,,,,,,,,,,OBI:0001205,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cell component comparison design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001164,age since sowing measurement datum,,"An age measurement datum that is the result of the measurement of the age of an organism since sowing, the process of placing a seed or spore in some media with the intention to invoke germination.",false,,,http://purl.obolibrary.org/obo/OBI_0001167,,,,,,,,,,,,,,,,,,,"An age measurement datum that is the result of the measurement of the age of an organism since sowing, the process of placing a seed or spore in some media with the intention to invoke germination.",MO_748 sowing,,,,,,age since sowing measurement datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001164,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,age since sowing measurement datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/GO_0002524,hypersensitivity,,An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system.,false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system.,,,,,,,hypersensitivity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0002524,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,hypersensitivity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000962,training objective,,An training objective which is fulfilled by the provision of some training,false,,,http://purl.obolibrary.org/obo/IAO_0000005,,,,,,,,,,,,,,,,,,,An training objective which is fulfilled by the provision of some training,OBI,,,,,,training objective,,A training objective is fulfilled by e.f. a bioconductor tutorial which instructs the user in the use of a package,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000962,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,training objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0001991,assay measuring the half maximal effective concentration [EC50] of a MHC:ligand complex,half maximal effective concentration (EC50)|binding assay|nM,A MHC binding constant determination assay measuring half maximal effective concentration (EC50).,false,,,http://purl.obolibrary.org/obo/OBI_0001553,,,,,,,,,,,,,,,,,,,A MHC binding constant determination assay measuring half maximal effective concentration (EC50).,IEDB,,,,,,assay measuring the half maximal effective concentration [EC50] of a MHC:ligand complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001991,,,,,,,,,,,,,,,,,,,,,,,,half maximal effective concentration (EC50)|binding assay|nM,,,,,,,,,,,,,,,,,,,,,,assay measuring the half maximal effective concentration [EC50] of a MHC:ligand complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/IAO_0000009,datum label,,A label is a symbol that is part of some other datum and is used to either partially define  the denotation of that datum or to provide a means for identifying the datum as a member of the set of data with the same label,false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,,,,,,,,,,,,,,"9/22/11 BP: changed the rdfs:label for this class from 'label' to 'datum label' to convey that this class is not intended to cover all kinds of labels (stickers, radiolabels, etc.), and not even all kind of textual labels, but rather the kind of labels occuring in a datum. 
",,A label is a symbol that is part of some other datum and is used to either partially define  the denotation of that datum or to provide a means for identifying the datum as a member of the set of data with the same label,,,,,,http://www.golovchenko.org/cgi-bin/wnsearch?q=label#4n,datum label,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000009,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,datum label,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP: IAO,,
http://purl.obolibrary.org/obo/OBI_0200120,variance calculation,,A variance calculation is a descriptive statistics calculation in which the variance is defined as the average squared distance of each observation in the data set to the mean of the data set.  It is also known as the second central moment.,false,,,http://purl.obolibrary.org/obo/OBI_0200184|http://purl.obolibrary.org/obo/OBI_0200086,,http://purl.obolibrary.org/obo/OBI_0200078|http://purl.obolibrary.org/obo/OBI_0200180,,,,,,,,,,,,,,,From Monnie's file comments - need to add spread_calculation and moment_calculation roles but they don't exist yet - (editor note added by James Jan 2008),,A variance calculation is a descriptive statistics calculation in which the variance is defined as the average squared distance of each observation in the data set to the mean of the data set.  It is also known as the second central moment.,PERSON: Monnie McGee,,,,,,variance calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,variance calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Monnie McGee,,
http://purl.obolibrary.org/obo/OBI_0001943,software pipeline,,"A plan specification that specifies a chain encoded in software of processing elements (processes, threads, coroutines, etc.), arranged so that the output of each element is the input of the next. Usually some amount of buffering is provided between consecutive elements.",false,,,http://purl.obolibrary.org/obo/IAO_0000104,,,,,,,,,,,,,,,,,,,"A plan specification that specifies a chain encoded in software of processing elements (processes, threads, coroutines, etc.), arranged so that the output of each element is the input of the next. Usually some amount of buffering is provided between consecutive elements.",WEB: http://en.wikipedia.org/wiki/Pipeline_%28software%29,,,,,,software pipeline,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001943,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,software pipeline,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Jie Zheng, Chris Stoeckert",,
http://purl.obolibrary.org/obo/OBI_1110008,occurrence of infectious disease,,Is an occurrence of a disease caused by an infection,false,,,http://purl.obolibrary.org/obo/OGMS_0000063,,,,,,,,,,,,,,,,,,,Is an occurrence of a disease caused by an infection,IEDB,,,,,,occurrence of infectious disease,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110008,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_1110003,,,,,,,,,,,,,,,,,,,,,occurrence of infectious disease,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001658,ELISPOT assay measuring binding of a B cell epitope:antibody complex,qualitative binding|ELISPOT,A B cell epitope qualitative binding to antibody assay that uses an enzyme-linked immunospot assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001703,,,,,,,,,,,,,,,,,,,A B cell epitope qualitative binding to antibody assay that uses an enzyme-linked immunospot assay.,IEDB,,,,,,ELISPOT assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001658,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_1110083,host of immune response role,,"is a role borne by an organism. It is realized by the organism during an immunization or an immune response taking place inside or on the surface of the organism, and in which the responding or stimulated immune system is part of the host.",false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,,,"is a role borne by an organism. It is realized by the organism during an immunization or an immune response taking place inside or on the surface of the organism, and in which the responding or stimulated immune system is part of the host.",IEDB,,,,,"03/21/2010: This sense of 'host' is used not only in infectious diseases but also allergy, cancer, transplantation, etc. which is why it is needed separately from the 'host of infectious agent' meaning, which will be imported from IDO.",host of immune response role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110083,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,host of immune response role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000569,mass selective detector,mass spectrometry detector,"A mass selective detector is a GC detector that uses mass spectrometry. It is based upon the ionization of solute molecules in the ion source and the separation of the ions generated on the basis of their mass/charge ratio by an analyzer unit. This may be a magnetic sector analyzer, a quadruple mass filter, or an ion trap. Ions are detected by a dynode electron multiplier.",false,,,http://purl.obolibrary.org/obo/OBI_0000637,,,,mass spectrometry detector,,,,,,,,,,,,,,,"A mass selective detector is a GC detector that uses mass spectrometry. It is based upon the ionization of solute molecules in the ion source and the separation of the ions generated on the basis of their mass/charge ratio by an analyzer unit. This may be a magnetic sector analyzer, a quadruple mass filter, or an ion trap. Ions are detected by a dynode electron multiplier.",WEB:<http://homepages.onsnet.nu/%7Ealkema/html/whatisgc.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01198,,,,,,mass selective detector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000569,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,mass selective detector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000496,capillary column,,"A capillary column is a thin tube with a small inner diameter, usually around 0.5 mm.",false,,,http://purl.obolibrary.org/obo/OBI_0000038,,,,,,,,,,,,,,,,,,,"A capillary column is a thin tube with a small inner diameter, usually around 0.5 mm.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01066,,,,,,capillary column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000496,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,capillary column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001696,in vivo assay measuring B cell epitope specific protection based on survival,survival from challenge|in vivo assay,A B cell epitope in vivo intervention experiment that uses a protection from challenge in vivo intervention experiment based on survival.,false,,,http://purl.obolibrary.org/obo/OBI_0001710,,,,,,,,,,,,,,,,,,,A B cell epitope in vivo intervention experiment that uses a protection from challenge in vivo intervention experiment based on survival.,IEDB,,,,,,in vivo assay measuring B cell epitope specific protection based on survival,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001982,,,,,,,,,,,,,,,,OBI:0001696,,,,,,,,,,,,,,,,,,,,,,,,survival from challenge|in vivo assay,,,,,,,,,,,,,,,,,,,,,,in vivo assay measuring B cell epitope specific protection based on survival,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/PR_000001018,CD3 subunit with immunoglobulin domain,,"A protein with a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response.",false,,,http://purl.obolibrary.org/obo/PR_000000001,,,,,,,,,,,,,,,,,,,"A protein with a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response.",,,,,,,CD3 subunit with immunoglobulin domain,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PR:000001018,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pr.owl,,,,,,,,,,,,,,,,,,,CD3 subunit with immunoglobulin domain,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000972,obsolete_electrically powered device,,a processed material created to have a function and which requires electrical power to execute,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,a processed material created to have a function and which requires electrical power to execute,,,,,,,obsolete_electrically powered device,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,OBI:0000972,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_electrically powered device,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001789,intracellular cytokine staining assay measuring epitope specific RANTES production by T cells,CCL5/RANTES release|ICS,An assay of epitope specific RANTES production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001232,,,,,,,,,,,,,,,,,,,An assay of epitope specific RANTES production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific RANTES production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001789,,,,,,,,,,,,,,,,,,,,,,,,CCL5/RANTES release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific RANTES production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000048,chromatography device,chromatography instrument,"a device that facilitates the separation of mixtures. The function of a chromatography device involves passing a mixture dissolved in a ""mobile phase"" through a stationary phase, which separates the analyte to be measured from other molecules in the mixture and allows it to be isolated.",false,,,http://purl.obolibrary.org/obo/OBI_0000967|http://purl.obolibrary.org/obo/OBI_0001034|http://purl.obolibrary.org/obo/OBI_0000832|http://purl.obolibrary.org/obo/OBI_0000932,,,,chromatography instrument,,,,,,,,,,,,,open tracker https://sourceforge.net/tracker/index.php?func=detail&aid=2881353&group_id=177891&atid=886178,,"a device that facilitates the separation of mixtures. The function of a chromatography device involves passing a mixture dissolved in a ""mobile phase"" through a stationary phase, which separates the analyte to be measured from other molecules in the mixture and allows it to be isolated.",http://en.wikipedia.org/wiki/Chromatography,,,,,,chromatography device,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453|http://purl.obolibrary.org/obo/OBI_0000370|http://purl.obolibrary.org/obo/OBI_0000372|http://purl.obolibrary.org/obo/OBI_0000401,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000048,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,chromatography device,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Frank Gibson,,
http://purl.obolibrary.org/obo/OBI_0000713,GenePattern software,,"a software that provides access to more than 100 tools for gene expression analysis, proteomics, SNP analysis and common data processing tasks.",false,,,http://purl.obolibrary.org/obo/IAO_0000010,,,,,,,,,,,,,,,,,,,"a software that provides access to more than 100 tools for gene expression analysis, proteomics, SNP analysis and common data processing tasks.",WEB: http://www.broadinstitute.org/cancer/software/genepattern/,,,,,,GenePattern software,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000713,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GenePattern software,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Helen Parkinson|James Malone,,
http://purl.obolibrary.org/obo/OBI_0001712,obsolete B cell epitope direct binding assay,direct binding assay,A direct binding assay using a assay,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,A direct binding assay using a assay,IEDB (QTT),,,,,,obsolete B cell epitope direct binding assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,OBI:0001712,,,,,,,,,,,,,,,,,,,,,,,,direct binding assay,,,,,,,,,,,,,,,,,,,,,,obsolete B cell epitope direct binding assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001269,biological activity assay measuring epitope specific cytotoxic T cell degranulation,degranulation|biological activity,A T cell epitope dependent biological activity assay that detects cytotoxic T cell degranulation.,false,,,http://purl.obolibrary.org/obo/OBI_0002055,,,,,,,,,,,,,,,,,,,A T cell epitope dependent biological activity assay that detects cytotoxic T cell degranulation.,IEDB,,,,,,biological activity assay measuring epitope specific cytotoxic T cell degranulation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001269,,,,,,,,,,,,,,,,,,,,,,,,degranulation|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific cytotoxic T cell degranulation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001167,age measurement datum,,A time measurement datum that is the result of measurement of age of an organism,false,,,http://purl.obolibrary.org/obo/IAO_0000416,,,,,,,,,,,,,,,,,"discussed on Nov 15, dev call
All subtype will be defined by textual definition now.|In MageTab file, we use
initialTimePoint (a process) + age (a number expected) + TimeUnit (definied in UO, such as year, hour, day, etc.)
Now we use the term label indicating the start time point of measuring the age, (number + TimeUnit) are expected instances of the class",,A time measurement datum that is the result of measurement of age of an organism,MO_178 Age,,,,,"note that we are currently defining subtypes of age measurement datum that specify when the age is relative to, e.g. planting, as we don't have adequate temporal predicates yet.
life of bearer doesn't imply organism
this assay measures time not developmental stage. we recognize that development can take different time periods under different conditions such as media / temperature
age as a quality is dubious; we plan to revisit
stages in development are currently handled with controlled vocabulary, such as 2-somite stage ",age measurement datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001167,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/PATO_0000011,,,,,http://purl.obolibrary.org/obo/OBI_0001158,,,age measurement datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Alan Ruttenberg, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000648,clustered data set,data set with assigned discovered class labels,A data set that is produced as the output of a class discovery data transformation and consists of a data set with assigned discovered class labels.,false,,,http://purl.obolibrary.org/obo/IAO_0000100,,,,data set with assigned discovered class labels,,,,,,,,,,,,,AR thinks could be a data item instead,,A data set that is produced as the output of a class discovery data transformation and consists of a data set with assigned discovered class labels.,,,,,,,clustered data set,,A clustered data set is the output of a K means clustering data transformation,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000648,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,clustered data set,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: James Malone|PERSON: Monnie McGee,,
http://purl.obolibrary.org/obo/GO_0005739,mitochondrion,,"A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.",false,,,http://purl.obolibrary.org/obo/GO_0043227,,,,,,,,,,,,,,,,,,,"A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.",,,,,,,mitochondrion,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0005739,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,mitochondrion,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001965,decision analysis study design,,a study design that has a decision analysis objective specification as part,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,a study design that has a decision analysis objective specification as part,PERSON: Bill Hogan,,,,,,decision analysis study design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001965,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,decision analysis study design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bill Hogan,,
http://purl.obolibrary.org/obo/OBI_0200027,total intensity transformation paired,,"A total intensity transformation paired is a data transformation that takes as input two n-dimensional (real) vectors and multiplies each component of the first vector by a coefficient, where the coefficient is obtained by taking the ratio of the sum of the second input components or of a subset of these by the sum of the first input components or of a subset of these (the same subset is used for the two vectors).",false,,,http://purl.obolibrary.org/obo/OBI_0200169,,http://purl.obolibrary.org/obo/OBI_0200167,,,,,,,,,,,,,,,"Note that if the word ""sum"" is replaced by the word ""mean"" in the definition, the resulting definition is equivalent.",,"A total intensity transformation paired is a data transformation that takes as input two n-dimensional (real) vectors and multiplies each component of the first vector by a coefficient, where the coefficient is obtained by taking the ratio of the sum of the second input components or of a subset of these by the sum of the first input components or of a subset of these (the same subset is used for the two vectors).",OTHER: Adjusted from MGED Ontology,,,,,,total intensity transformation paired,,This can be used as a simple normalization method for the two channels from a two-channel expression microarray assay or from two related one-channel expression microarray assays.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200027,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,total intensity transformation paired,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001600,biological activity assay measuring epitope specific granulocyte colony stimulating factor production by T cells,G-CSF release|biological activity,A T cell epitope specific cytokine production assay that detects granulocyte colony stimulating factor production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects granulocyte colony stimulating factor production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific granulocyte colony stimulating factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001600,,,,,,,,,,,,,,,,,,,,,,,,G-CSF release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific granulocyte colony stimulating factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0302736,comet assay,SCGE assay|single cell gel electrophoresis  assay,a comet assay is an assay which utilizes gel electrophoresis on cell exposed to a challenge with the objective to assess DNA damage (DNA breakage) by determining the size and shape of DNA migration in cell placed in an electric field in specific conditions.,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,http://purl.obolibrary.org/obo/OBI_0000441,,SCGE assay|single cell gel electrophoresis  assay,,,,,,,,,,,,,,,a comet assay is an assay which utilizes gel electrophoresis on cell exposed to a challenge with the objective to assess DNA damage (DNA breakage) by determining the size and shape of DNA migration in cell placed in an electric field in specific conditions.,PMID:7686265 .Mutat Res. 1993 Jul;288(1):47-63.The single cell gel electrophoresis assay (comet assay): a European review.,,,,,,comet assay,,PMID: 18326531.Mutagenesis. 2008 Mar 6.Recommendations for design of the rat comet assay.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0400140|http://purl.obolibrary.org/obo/OBI_0400142,,,,,,,,,,,http://purl.obolibrary.org/obo/CL_0000000|http://purl.obolibrary.org/obo/OBI_0000439,,,,OBI:0302736,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,comet assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000837,oral ingestion of pill,,An adding a material entity to target with the entity is a pill and the target is the mouth,false,,,http://purl.obolibrary.org/obo/OBI_0000952,,,,,,,,,,,,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,,An adding a material entity to target with the entity is a pill and the target is the mouth,,,,,,,oral ingestion of pill,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000837,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,oral ingestion of pill,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0400113,oligonucleotide synthesizer,,An instrument used to chemically synthesize oligonucleotides.,false,,,http://purl.obolibrary.org/obo/OBI_0001034,,,,,,,,,,,,,,,,,,,An instrument used to chemically synthesize oligonucleotides.,MO,,,,,,oligonucleotide synthesizer,,Automated Multiplex Oligonucleotide Synthesizer,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/OBI_0000401|http://purl.obolibrary.org/obo/OBI_0000376,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400113,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,oligonucleotide synthesizer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Trish Whetzel,,
http://purl.obolibrary.org/obo/OBI_0000566,NMR instrument,NMR instrument,An Instrument which is used to carry out a NMR analysis of some sample.,false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,NMR instrument,,,,,,,,,,,,,NMR instrument,,An Instrument which is used to carry out a NMR analysis of some sample.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400059,,,,,,NMR instrument,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000566,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NMR instrument,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0400012,Bactiflow,,"A Bactiflow is a flow_cytometer_analyser manufactured by Chemunex SA. It is a cell counter for bacteria and other micro organisms. Bacteria are stained with a fluorochrome and the number of particles that fluoresce are counted. The system uses digital electronics, a single laser and a single detector. An ALS version is available as well - Automatic Labeling System. The Bactiflow is specialized cytometer used exclusively for counting microbes.",false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,,,,,,,,,,,,,,,,"A Bactiflow is a flow_cytometer_analyser manufactured by Chemunex SA. It is a cell counter for bacteria and other micro organisms. Bacteria are stained with a fluorochrome and the number of particles that fluoresce are counted. The system uses digital electronics, a single laser and a single detector. An ALS version is available as well - Automatic Labeling System. The Bactiflow is specialized cytometer used exclusively for counting microbes.",http://www.chemunex.com/products/chemframe.htm,,,,,,Bactiflow,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400012,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bactiflow,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0000947,service provider role,,"is a role which inheres in a person or organization and is realized in in a planned process which provides access to training, materials or execution of protocols for an organization or person",false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,,,"is a role which inheres in a person or organization and is realized in in a planned process which provides access to training, materials or execution of protocols for an organization or person",,,,,,,service provider role,,"Jackson Lab provides experimental animals, EBI provides training on databases, a core facility provides access to a DNA sequencer.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000947,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,service provider role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Helen Parkinson,,
http://purl.obolibrary.org/obo/IAO_0000311,publication,,A document that has been accepted by a publisher,false,,,http://purl.obolibrary.org/obo/IAO_0000310,,,,,,,,,,,,,,,,,,,A document that has been accepted by a publisher,,,,,,,publication,,A journal article or book,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000311,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,publication,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0001480,phage display library panning,,"Phage display library panning is a process in which a diverse collection of phages encoding peptides or proteins are screened and the ones encoding active peptides/proteins are selected in an iterative process similar to natural selection.
",false,,,http://purl.obolibrary.org/obo/OBI_0000094,,,,,,,,,,,,,,,,,,,"Phage display library panning is a process in which a diverse collection of phages encoding peptides or proteins are screened and the ones encoding active peptides/proteins are selected in an iterative process similar to natural selection.
","IEDB, http://en.wikipedia.org/wiki/Phage_display",,,,,,phage display library panning,,Screening a libray of M13 phages displaying random peptide sequences for binding to the MHC molecule HLA-A*02:02 resulting in a subset of phages that encode peptides that bind. ,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_1000029,,,,OBI:0001480,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,phage display library panning,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Jason Greenbaum, Randi Vita, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000799,recombinant phage cloning,,Recombinant phage cloning is the process of using a phage plus some insert nucleic acid for the purposes of amplification of the insert material achieved by phage assembly in vitro.,false,,,http://purl.obolibrary.org/obo/OBI_0600064,,,,,,,,,,,,,,,,,,,Recombinant phage cloning is the process of using a phage plus some insert nucleic acid for the purposes of amplification of the insert material achieved by phage assembly in vitro.,http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=mcb.section.1611,,,,,,recombinant phage cloning,,Insert selection by BamHI methyltransferase protection in P1 phage-based cloning,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000799,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,recombinant phage cloning,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Helen Parkinson,,
http://purl.obolibrary.org/obo/PATO_0000018,fluorescence,,A luminous flux quality inhering in a bearer by virtue of the bearer's emitting longer wavelength light following the absorption of shorter wavelength radiation; fluorescence is common with aromatic compounds with several rings joined together.,false,,,http://purl.obolibrary.org/obo/BFO_0000016,,,,,,,,,,,,,,,,,,,A luminous flux quality inhering in a bearer by virtue of the bearer's emitting longer wavelength light following the absorption of shorter wavelength radiation; fluorescence is common with aromatic compounds with several rings joined together.,,,,,,,fluorescence,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0000018,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,fluorescence,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0000011,age,,A time quality inhering in a bearer by virtue of how long the bearer has existed.,false,,,http://purl.obolibrary.org/obo/PATO_0001237,,,,,,,,,,,,,,,,,,,A time quality inhering in a bearer by virtue of how long the bearer has existed.,,,,,,,age,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0000011,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,age,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0500004,n-to-1 design,,"N-of-1 design is a cross-over design in which the same patient is repeatedly randomised to receive either the experimental treatment or its control (Senn, 1993).",false,,,http://purl.obolibrary.org/obo/OBI_0500003,,,,,,,,,,,,,,,,,,,"N-of-1 design is a cross-over design in which the same patient is repeatedly randomised to receive either the experimental treatment or its control (Senn, 1993).",Adapted from  http://www.childrens-mercy.org/stats/definitions/crossover.htm and source:http://symptomresearch.nih.gov/chapter_6/sec1/csss1pg1.htm),,,,,,n-to-1 design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500004,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,n-to-1 design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0002006,1M-Duo Infinium HD BeadChip,Illumina Human 1M-Duo Infinium HD BeadChip,"A BeadChip which is manufactured by the Illumina corporation. Built upon BeadChip tehcnology, the array integrates ~ 1 million markers per sample for genotyping, and copy number variation (CNV) and Cytogenetic analysis.",false,,,http://purl.obolibrary.org/obo/OBI_0001869,,,,Illumina Human 1M-Duo Infinium HD BeadChip,,,,,,,,,,,,,,,"A BeadChip which is manufactured by the Illumina corporation. Built upon BeadChip tehcnology, the array integrates ~ 1 million markers per sample for genotyping, and copy number variation (CNV) and Cytogenetic analysis.",http://www.illumina.com/technology/infinium_hd_assay.ilmn,,,,,,1M-Duo Infinium HD BeadChip,,"Edwards, Todd L., et al. ""Genome-Wide Association Study Confirms SNPs in SNCA and the MAPT Region as Common Risk Factors for Parkinson Disease."" Annals of human genetics 74.2 (2010): 97-109. PMID: 20070850",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002006,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1M-Duo Infinium HD BeadChip,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"PERSON: Venkat Malladi, Chris Stoeckert, Jie Zheng, Alan Ruttenberg",,
http://purl.obolibrary.org/obo/IAO_0000416,time measurement datum,,A scalar measurement datum that is the result of measuring a temporal interval,false,,,http://purl.obolibrary.org/obo/IAO_0000032,,,,,,,,,,,,,,,,,,,A scalar measurement datum that is the result of measuring a temporal interval,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,time measurement datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000416,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,time measurement datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0000695,chain termination sequencing,Sanger sequencing|dye terminator sequencing,"is a DNA sequencing which rely on the use of dideoxynucleotides used in 4 distinct sequencing reaction on the same DNA sample. The dideoxynucleotides, once incorporated in the complementary DNA strand being synthesized by the DNA polymerase prevent any further chain elongation. The newly generated sequences are resolved on a polyacrylamide gel using electrophoresis and labels (either fluorochrome or radioactivity) are used to determine the nucleotide present at a given position",false,,,http://purl.obolibrary.org/obo/OBI_0000734,,,,Sanger sequencing|dye terminator sequencing,,,,,,,,,,,,,,,"is a DNA sequencing which rely on the use of dideoxynucleotides used in 4 distinct sequencing reaction on the same DNA sample. The dideoxynucleotides, once incorporated in the complementary DNA strand being synthesized by the DNA polymerase prevent any further chain elongation. The newly generated sequences are resolved on a polyacrylamide gel using electrophoresis and labels (either fluorochrome or radioactivity) are used to determine the nucleotide present at a given position",adapted from wikipedia,,,,,,chain termination sequencing,,"PMID: 271968. DNA sequencing with chain-terminating inhibitors.
Sanger F, Nicklen S, Coulson AR. Proc Natl Acad Sci U S A. 1977 Dec;74(12):5463-7.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000406,,,,OBI:0000695,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,chain termination sequencing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000800,cross linking,,A process in which bonds are created that link one polymer to another,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,A process in which bonds are created that link one polymer to another,http://en.wikipedia.org/wiki/Cross-link,,,,,,cross linking,,"cross linking can be used as a probe to link proteins together, to check protein protein interactions",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,OBI:0000800,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cross linking,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0001066,top loading balance,,A balance that consists of a metal plate on which to place an object and a digital readout of the measurement of its mass.,false,,,http://purl.obolibrary.org/obo/OBI_0001135,,,,,,,,,,,,,,,,,,,A balance that consists of a metal plate on which to place an object and a digital readout of the measurement of its mass.,PERSON: Erik Segerdell,,,,,,top loading balance,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001066,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,top loading balance,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001732,quenching assay measuring the association constant [KA] of a B cell epitope:antibody complex,association constant KA|quenching|1/nM,A B cell epitope equilibrium association constant (KA) determination assay that uses an antibody binding detection by fluorescence quenching assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001499|http://purl.obolibrary.org/obo/OBI_0001719,,,,,,,,,,,,,,,,,,,A B cell epitope equilibrium association constant (KA) determination assay that uses an antibody binding detection by fluorescence quenching assay.,IEDB,,,,,,quenching assay measuring the association constant [KA] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001732,,,,,,,,,,,,,,,,,,,,,,,,association constant KA|quenching|1/nM,,,,,,,,,,,,,,,,,,,,,,quenching assay measuring the association constant [KA] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0100051,specimen,,A material entity that has the specimen role.,false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,A material entity that has the specimen role.,GROUP: OBI Biomaterial Branch,,,,,Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation.,specimen,,Biobanking of blood taken and stored in a freezer for potential future investigations stores specimen.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0100051,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,specimen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: James Malone|PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001859,formaldehyde-assisted isolation of regulatory elements assay,FAIRE-seq assay|FAIRE-seq,An assay to determine the sequences of those DNA regions in the genome associated with regulatory activity.,false,,,http://purl.obolibrary.org/obo/OBI_0000626,,http://purl.obolibrary.org/obo/OBI_0001398,,FAIRE-seq assay|FAIRE-seq,,,,,,,,,,,,,,,An assay to determine the sequences of those DNA regions in the genome associated with regulatory activity.,http://en.wikipedia.org/wiki/FAIRE-Seq,,,,,,formaldehyde-assisted isolation of regulatory elements assay,,"Giresi, et al. FAIRE (Formaldehyde-Assisted Isolation of Regulatory Elements) isolates active regulatory elements from human chromatin. Genome Research 17 (6): 877–85. [PMID:17179217]",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000800|http://purl.obolibrary.org/obo/OBI_0000711|http://purl.obolibrary.org/obo/OBI_0000626,http://purl.obolibrary.org/obo/OBI_0400103|http://purl.obolibrary.org/obo/OBI_0400114,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001573,,,OBI:0001859,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,formaldehyde-assisted isolation of regulatory elements assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001653,immunoprecipitation assay measuring binding of a B cell epitope:antibody complex,qualitative binding|immunoprecipitation,A B cell epitope qualitative binding to antibody assay that uses an immunoprecipitation assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001703,,,,,,,,,,,,,,,,,,,A B cell epitope qualitative binding to antibody assay that uses an immunoprecipitation assay.,IEDB,,,,,,immunoprecipitation assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001653,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|immunoprecipitation,,,,,,,,,,,,,,,,,,,,,,immunoprecipitation assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000109,biological vector role,,a biological vector role is a material to be added role that is realized by the process of transmitting material to the organism that is the target of the transmission.,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,"6/12/2009 Alan made this a material to be added role, because it was, and because this speeded up reasoning",,a biological vector role is a material to be added role that is realized by the process of transmitting material to the organism that is the target of the transmission.,OBI and Wikipedia,,,,,"false|Feb 20, 2009. The material transmitted can be genetic information (as in cloning vector) or a pathogen (as in a disease vector)",biological vector role,,1983 Sci. Amer. Jan. 58/2 Plasmids are routinely used as vectors for introducing foreign DNA into bacteria.|Some epidemiological aspects and vector role of tick infestation on layers in the Faisalabad district (Pakistan). http://journals.cambridge.org/action/displayAbstract;jsessionid=0373164489D00868AEEF2C556EB4FD29.tomcat1?fromPage=online&aid=624280,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,OBI:0000109,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,biological vector role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP:  Role Branch,,
http://purl.obolibrary.org/obo/OBI_0000610,auto injector,,A gas chromatography device that can auto-inject a small number of samples an inlet.,false,,,http://purl.obolibrary.org/obo/OBI_0000504,,,,,,,,,,,,,,,,,,,A gas chromatography device that can auto-inject a small number of samples an inlet.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01058,,,,,,auto injector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000610,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,auto injector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001819,epitope specific chemokine (C-C motif) ligand 22 production by T cells,,A process of chemokine (C-C motif) ligand 22 production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0071924|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,Date: 2012-11-16; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mappings: MMExpressionsTcell.txt,,A process of chemokine (C-C motif) ligand 22 production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific chemokine (C-C motif) ligand 22 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001819,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific chemokine (C-C motif) ligand 22 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0400081,particle delivery vessel,,Part of the fluidics subsystem. A particle delivery vessel is used to introduce either a single sample or multiple samples to a flow cytometer. The most common particle delivery vessel is a sample tube.,false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,,,,,,,,,,,,,,FG: this should be delted - particle delivery is a role that an object can play,,Part of the fluidics subsystem. A particle delivery vessel is used to introduce either a single sample or multiple samples to a flow cytometer. The most common particle delivery vessel is a sample tube.,"Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253",,,,,,particle delivery vessel,,FC 500 particle delivery vessel,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400081,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,particle delivery vessel,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0000787,human antithrombin-III (AT-III) in blood assay,,An assay to measure the amount of antithrombin III in blood.,false,,,http://purl.obolibrary.org/obo/OBI_0000443,,,,,,,,,,,,,,,,,,,An assay to measure the amount of antithrombin III in blood.,WEB:http://www.muschealth.com/lab/content.aspx?id=150006@2009/08/06,,,,,,human antithrombin-III (AT-III) in blood assay,,PMID:19696660#The antithrombin-III (AT-III) was determined using a Berichrom(r) Antithrombin-III (A) kit.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000787,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,human antithrombin-III (AT-III) in blood assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0000370,contain function,,A contain function is a function to constrain a material entities location in space,false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,A contain function is a function to constrain a material entities location in space,,,,,,,contain function,,"A syringe, a beaker",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000370,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,contain function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bill Bug|Daniel Schober|Frank Gibson|Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0001608,purified MHC direct binding assay of a MHC:ligand complex using radioactivity detection,qualitative binding|purified MHC/direct/radioactivity,A purified MHC binding assay that uses radioactivity detection to measure direct ligand binding.,false,,,http://purl.obolibrary.org/obo/OBI_0001555|http://purl.obolibrary.org/obo/OBI_0001491,,,,,,,,,,,,,,,,,,,A purified MHC binding assay that uses radioactivity detection to measure direct ligand binding.,IEDB,,,,,,purified MHC direct binding assay of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000201,,,,,,,,,,,,,,,,OBI:0001608,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|purified MHC/direct/radioactivity,,,,,,,,,,,,,,,,,,,,,,purified MHC direct binding assay of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001385,intracellular cytokine staining assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells,TNF release|ICS,An assay of epitope specific tumor necrosis factor superfamily cytokine production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001400,,,,,,,,,,,,,,,,,,,An assay of epitope specific tumor necrosis factor superfamily cytokine production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001385,,,,,,,,,,,,,,,,,,,,,,,,TNF release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001895,specimen collector,Specimen Collector Name,A person who collects the specimen,false,,,http://purl.obolibrary.org/obo/NCBITaxon_9606,,,,,,,,,,,,,,,,,,,A person who collects the specimen,NIAID GSCID-BRC metadata working group,,,,,,specimen collector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001895,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,specimen collector,,,,,,Specimen Collector Name,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/CHEBI_51756,Alexa Fluor 532,,An organosulfonic acid that has formula C34H33N3O11S2.,false,,,http://purl.obolibrary.org/obo/REO_0000280,,,,,,,,,,,,,,,,,,,An organosulfonic acid that has formula C34H33N3O11S2.,,,,,,,Alexa Fluor 532,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/REO_0000171,,,,,,,,,,,,CHEBI:51756,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,Alexa Fluor 532,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001663,ELISA measuring epitope specific granulysin release by T cells,granulysin release|ELISA,A T cell epitope specific granulysin release assay that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001810,,,,,,,,,,,,,,,,,,,A T cell epitope specific granulysin release assay that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific granulysin release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001663,,,,,,,,,,,,,,,,,,,,,,,,granulysin release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific granulysin release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001426,sex comparison design,,"A study design that assays differences associated with an organism's sex, gender or mating type.",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A study design that assays differences associated with an organism's sex, gender or mating type.",MO_575 sex_design,,,,,,sex comparison design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000268,,,,,,,,,,,,,,,,OBI:0001426,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sex comparison design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001852,paired-end library preparation,,A library preparation that results in the creation of a library of the 5' and 3' ends of DNA or cDNA fragments using adaptors and endonucleases. The preparation may or may not include cloning process. ,false,,,http://purl.obolibrary.org/obo/OBI_0000711,,,,,,,,,,,,,,,,,,,A library preparation that results in the creation of a library of the 5' and 3' ends of DNA or cDNA fragments using adaptors and endonucleases. The preparation may or may not include cloning process. ,"Venkat Malladi, Jie Zheng",,,,,,paired-end library preparation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001852,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,paired-end library preparation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001214,normalization testing design,,A study design that tests different normalization procedures.,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,A study design that tests different normalization procedures.,MO_729 normalization_testing_design,,,,,,normalization testing design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000242,,,,,,,,,,,,,,,,OBI:0001214,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,normalization testing design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001420,epitope specific helper T cell enhancement of T cell mediated immune response,,A process of helper T cell enhancement of T cell mediated immune response resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0035398,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of helper T cell enhancement of T cell mediated immune response resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific helper T cell enhancement of T cell mediated immune response,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001420,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific helper T cell enhancement of T cell mediated immune response,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_1110093,disposition to infect an organism,,"Is a role borne by an agent, and realized when in contact with or inside another organism in which it is capable of replicating and causing disease",false,,,http://purl.obolibrary.org/obo/BFO_0000016,,,,,,,,,,,,,,,,,,,"Is a role borne by an agent, and realized when in contact with or inside another organism in which it is capable of replicating and causing disease",IEDB,,,,,,disposition to infect an organism,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110093,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,disposition to infect an organism,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001154,induced mutation,,a genetic transformation that the modification of the genetic material (either coding or non-coding) of an organism is caused by mutagenic compounds or irradiation.,false,,,http://purl.obolibrary.org/obo/OBI_0600043,,,,,,,,,,,,,,,,,,,a genetic transformation that the modification of the genetic material (either coding or non-coding) of an organism is caused by mutagenic compounds or irradiation.,MO_564 induced_mutation,,,,,,induced mutation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001154,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,induced mutation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000724,Solexa sequencing,reversible terminator sequencing,is a DNA sequencing which allows sequence identification by relying on use of DNA polymerase and reversible terminator. The methods requires immobilization of genomic DNA fragment onto a surface and a specific clonal amplification step known as bridge PCR. Reliance on reversible terminator allow cycles of DNA chain extension by DNA polymerase and imaging without the need of electrophoretic separation of newly synthesized DNA fragment as with Sanger sequencing.,false,,,http://purl.obolibrary.org/obo/OBI_0000734,,,,reversible terminator sequencing,,,,,,,,,,,,,,,is a DNA sequencing which allows sequence identification by relying on use of DNA polymerase and reversible terminator. The methods requires immobilization of genomic DNA fragment onto a surface and a specific clonal amplification step known as bridge PCR. Reliance on reversible terminator allow cycles of DNA chain extension by DNA polymerase and imaging without the need of electrophoretic separation of newly synthesized DNA fragment as with Sanger sequencing.,adapted from Wikipedia and Illumina / Solexa web site (SS_DNAsequencing.pdf document available on july 2009),,,,,,Solexa sequencing,,"PMID: 18987734
Accurate whole human genome sequencing using reversible terminator chemistry. Bentley DR, Balasubramanian S, Swerdlow HP, Smith GP, Milton J, Brown CG, Hall KP, Evers DJ, Barnes CL, Bignell HR, Boutell JM, Bryant J, Carter RJ, Keira Cheetham R, Cox AJ, Ellis DJ, Flatbush MR, Gormley NA, Humphray SJ, Irving LJ, Karbelashvili MS, Kirk SM, Li H, Liu X, Maisinger KS, Murray LJ, Obradovic B, Ost T, Parkinson ML, Pratt MR, Rasolonjatovo IM, Reed MT, Rigatti R, Rodighiero C, Ross MT, Sabot A, Sankar SV, Scally A, Schroth GP, Smith ME, Smith VP, Spiridou A, Torrance PE, Tzonev SS, Vermaas EH, Walter K, Wu X, Zhang L, Alam MD, Anastasi C, Aniebo IC, Bailey DM, Bancarz IR, Banerjee S, Barbour SG, Baybayan PA, Benoit VA, Benson KF, Bevis C, Black PJ, Boodhun A, Brennan JS, Bridgham JA, Brown RC, Brown AA, Buermann DH, Bundu AA, Burrows JC, Carter NP, Castillo N, Chiara E Catenazzi M, Chang S, Neil Cooley R, Crake NR, Dada OO, Diakoumakos KD, Dominguez-Fernandez B, Earnshaw DJ, Egbujor UC, Elmore DW, Etchin SS, Ewan MR, Fedurco M, Fraser LJ, Fuentes Fajardo KV, Scott Furey W, George D, Gietzen KJ, Goddard CP, Golda GS, Granieri PA, Green DE, Gustafson DL, Hansen NF, Harnish K, Haudenschild CD, Heyer NI, Hims MM, Ho JT, Horgan AM, Hoschler K, Hurwitz S, Ivanov DV, Johnson MQ, James T, Huw Jones TA, Kang GD, Kerelska TH, Kersey AD, Khrebtukova I, Kindwall AP, Kingsbury Z, Kokko-Gonzales PI, Kumar A, Laurent MA, Lawley CT, Lee SE, Lee X, Liao AK, Loch JA, Lok M, Luo S, Mammen RM, Martin JW, McCauley PG, McNitt P, Mehta P, Moon KW, Mullens JW, Newington T, Ning Z, Ling Ng B, Novo SM, O'Neill MJ, Osborne MA, Osnowski A, Ostadan O, Paraschos LL, Pickering L, Pike AC, Pike AC, Chris Pinkard D, Pliskin DP, Podhasky J, Quijano VJ, Raczy C, Rae VH, Rawlings SR, Chiva Rodriguez A, Roe PM, Rogers J, Rogert Bacigalupo MC, Romanov N, Romieu A, Roth RK, Rourke NJ, Ruediger ST, Rusman E, Sanches-Kuiper RM, Schenker MR, Seoane JM, Shaw RJ, Shiver MK, Short SW, Sizto NL, Sluis JP, Smith MA, Ernest Sohna Sohna J, Spence EJ, Stevens K, Sutton N, Szajkowski L, Tregidgo CL, Turcatti G, Vandevondele S, Verhovsky Y, Virk SM, Wakelin S, Walcott GC, Wang J, Worsley GJ, Yan J, Yau L, Zuerlein M, Rogers J, Mullikin JC, Hurles ME, McCooke NJ, West JS, Oaks FL, Lundberg PL, Klenerman D, Durbin R, Smith AJ. Nature. 2008 Nov 6;456(7218):53-9.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000703,,,,,,,,,,,,,,,OBI:0000724,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Solexa sequencing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001773,biological activity assay measuring epitope specific interleukin-17A production by T cells,IL-17A release|biological activity,An assay of epitope specific interleukin-17 production by T cells that detects interleukin-17A production.,false,,,http://purl.obolibrary.org/obo/OBI_0001295,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-17 production by T cells that detects interleukin-17A production.,IEDB,,,,,,biological activity assay measuring epitope specific interleukin-17A production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001773,,,,,,,,,,,,,,,,,,,,,,,,IL-17A release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific interleukin-17A production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001248,ChIP-chip assay,ChIP-on-chip assay,"an assay that aims to investigate the interactions between protein and DNA relying on chromatin immunoprecipitation ('ChIP') combined with microarray technology ('chip'). Specially, it allows the identification of protein binding sites on a genome-wide basis.|Philippe Rocca-Serra",false,,,http://purl.obolibrary.org/obo/OBI_0001956,,http://purl.obolibrary.org/obo/OBI_0001398,,ChIP-on-chip assay,,,,,,,,,,,,,,,"an assay that aims to investigate the interactions between protein and DNA relying on chromatin immunoprecipitation ('ChIP') combined with microarray technology ('chip'). Specially, it allows the identification of protein binding sites on a genome-wide basis.",WEB: http://en.wikipedia.org/wiki/ChIP-on-chip,,,,,,ChIP-chip assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000690,http://purl.obolibrary.org/obo/OBI_0400148,,,,,,,,,,,,,,,OBI:0001248,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,,,,,,,,,,,,,,,,,,,,,,,,,,,ChIP-chip assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: James Malone,,
http://purl.obolibrary.org/obo/GO_0035746,granzyme A production,,"The appearance of granzyme A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,"The appearance of granzyme A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,granzyme A production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0035746,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,granzyme A production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000919,animal euthanization,animal sacrifice,A process in which is the end of life of animal is brought about in accordance with local regulations on treatment of animal subjects and using a method which causes minimal pain and distress to the animal subject|may later be refined with more specific list of organisms,false,,,http://purl.obolibrary.org/obo/OBI_0600006,,,,animal sacrifice,,,,,,,,,,,,,,,A process in which is the end of life of animal is brought about in accordance with local regulations on treatment of animal subjects and using a method which causes minimal pain and distress to the animal subject,Melissa Haendel,,,,,,animal euthanization,,Rats were euthanized with CO2,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/NCBITaxon_7742,,,,OBI:0000919,,,,,,,,,,,,,,,,,,may later be refined with more specific list of organisms,,,,,,,,,,,,,,,,,,,,,,,,,,,,animal euthanization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Helen Parkinson and Melissa Haendel,,
http://purl.obolibrary.org/obo/OBI_0002043,individual-nucleotide resolution cross-linking and immunoprecipitation sequencing assay,individual-nucleotide resolution cross-linking and immunoprecipitation|iCLIP assay|iCLIP,"A cross-linking immunoprecipitation high-throughput sequencing assay to identify protein-RNA interactions by using UV light to covalently bind proteins and RNA molecules, allowing for a very stringent purification of the linked protein-RNA complexes.",false,,,http://purl.obolibrary.org/obo/OBI_0001858,,,,individual-nucleotide resolution cross-linking and immunoprecipitation|iCLIP assay|iCLIP,,,,,,,,,,,,,,,"A cross-linking immunoprecipitation high-throughput sequencing assay to identify protein-RNA interactions by using UV light to covalently bind proteins and RNA molecules, allowing for a very stringent purification of the linked protein-RNA complexes.","Huppertz et al., (February 2014). ""iCLIP: protein-RNA interactions at nucleotide resolution."". Methods (San Diego, Calif.) 65 (3): 274-87. doi:10.1016/j.ymeth.2013.10.011",,,,,,individual-nucleotide resolution cross-linking and immunoprecipitation sequencing assay,,"König et al., (18 January 2012). ""Protein-RNA interactions: new genomic technologies and perspectives"". Nature Reviews Genetics 13 (2): 77-83. doi:10.1038/nrg3141",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002043,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,individual-nucleotide resolution cross-linking and immunoprecipitation sequencing assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001811,cytometric bead array assay measuring epitope specific interleukin-27 production by T cells,IL-27 release|cytometric bead array,An assay of epitope specific interleukin-27 production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001198,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-27 production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific interleukin-27 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001811,,,,,,,,,,,,,,,,,,,,,,,,IL-27 release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific interleukin-27 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001238,ELISA measuring epitope specific interleukin-9 production by T cells,IL-9 release|ELISA,An assay of epitope specific interleukin-9 production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001253,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-9 production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific interleukin-9 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001238,,,,,,,,,,,,,,,,,,,,,,,,IL-9 release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific interleukin-9 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001342,intracellular cytokine staining assay measuring epitope specific interleukin-21 production by T cells,IL-21 release|ICS,An assay of epitope specific interleukin-21 production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001237,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-21 production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-21 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001342,,,,,,,,,,,,,,,,,,,,,,,,IL-21 release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-21 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/CL_0000057,fibroblast,,A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.,false,,,http://purl.obolibrary.org/obo/CL_0000000,,,,,,,,,,,,,,,,,,,A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.,,,,,,,fibroblast,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CL:0000057,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/cl.owl,,,,,,,,,,,,,,,,,,,fibroblast,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000103,principal investigator role,principal investigator,a responsible party role played by a person responsible for the overall conduct of a study,false,,,http://purl.obolibrary.org/obo/OBI_0000102,,,,principal investigator,,,,,,,,,,,,,"CDISC definition: A person responsible for the conduct of the clinical trial at a trial site. If a trial is conducted by a team of individuals at a trial site, the investigator is the responsible leader of the team and may be called the principal investigator. 2. The individual principal investigator. 2. The individual under whose immediate direction the test article is administered or dispensed to, or used involving, a subject, or, in the event of an investigation conducted by a team of individuals, is See also sponsor-investigator.; Leiter der klinischen Prufung.Under the German Drug Law, the physician who is head of the clinical investigation (CDISC): coordinating investigator (CDISC) (also study coordinator, MUSC); sponsor-investigator. An individual who both initiates and conducts, alone or with others, a clinical trial, and under whose immediate direction the investigational product is administered to, dispensed to, or used by a subject.NOTE: The term does not include any person other than an individual, hence not a corporation, agency (CDISC)",,a responsible party role played by a person responsible for the overall conduct of a study,,,,,,,principal investigator role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000103,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,principal investigator role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_1110002,obsolete_occurrence of disease,,An occurrence of disease is a process involving pathologic changes within an organism,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,An occurrence of disease is a process involving pathologic changes within an organism,IEDB,,,,,"replaced by http://purl.obolibrary.org/obo/OGMS_0000063 'disease course'
Details see https://sourceforge.net/tracker/?func=detail&aid=3515228&group_id=177891&atid=886178",obsolete_occurrence of disease,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000228,,,,,,,,,,,,,,,,,,OBI:1110002,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_occurrence of disease,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0200033,leave one out cross validation method,,"is a data transformation :  leave-one-out cross-validation (LOOCV) involves using a single observation from the original sample as the validation data, and the remaining observations as the training data. This is repeated such that each observation in the sample is used once as the validation data",false,,,http://purl.obolibrary.org/obo/OBI_0000792,,http://purl.obolibrary.org/obo/OBI_0200188,,,,,,,,,,,,,,,,,"is a data transformation :  leave-one-out cross-validation (LOOCV) involves using a single observation from the original sample as the validation data, and the remaining observations as the training data. This is repeated such that each observation in the sample is used once as the validation data",,,,,,2009-11-10. Tracker: https://sourceforge.net/tracker/?func=detail&aid=2893049&group_id=177891&atid=886178,leave one out cross validation method,,The authors conducted  leave-one-out cross validation to estimate the strength and accuracy of the differentially expressed filtered genes. http://bioinformatics.oxfordjournals.org/cgi/content/abstract/19/3/368,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200033,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,leave one out cross validation method,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0001158,age measurement assay,,"An assay that measures the duration of temporal interval of a process that is part of the life of the bearer, where the initial time point of the measured process is the beginning of some transitional state of the bearer such as birth or when planted.",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,"An assay that measures the duration of temporal interval of a process that is part of the life of the bearer, where the initial time point of the measured process is the beginning of some transitional state of the bearer such as birth or when planted.",OBI group,,,,,"This assay measures time not developmental stage.  we recognize that development takes different time periods under different conditions such as media / temperature. For example, age measurement assay of fly age, the output likes 28 days but not mid-life of age at room temperature.",age measurement assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001167,,,OBI:0001158,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,age measurement assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0200025,loess scale group transformation,,"A loess scale group transformation is a data transformation consisting in the application of a scale adjustment following a loess group transformation, to render the group variances for the second variable (y) similar.  Has objective scaling.",false,,,http://purl.obolibrary.org/obo/OBI_0200185,,http://purl.obolibrary.org/obo/OBI_0200183,,,,,,,,,,,,,,,,,"A loess scale group transformation is a data transformation consisting in the application of a scale adjustment following a loess group transformation, to render the group variances for the second variable (y) similar.  Has objective scaling.",OTHER: Editor's generalization based on MGED Ontology term,,,,,,loess scale group transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200025,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0200024,,,,,,,,,,,,,,,,,,,,,loess scale group transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Melanie Courtot|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_1110040,infectious disease,,is a disease caused by an infectious agent,false,,,http://purl.obolibrary.org/obo/OGMS_0000031,,,,,,,,,,,,,,,,,,,is a disease caused by an infectious agent,IEDB,,,,,,infectious disease,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110040,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,infectious disease,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001892,specification of data to be generated in an investigation,Project Objectives,An objective specification which indicates the type of data that will be generated and submitted to a database.,false,,,http://purl.obolibrary.org/obo/IAO_0000005,,,,,,,,,,,,,,,,,,,An objective specification which indicates the type of data that will be generated and submitted to a database.,NIAID GSCID-BRC metadata working group,,,,,,specification of data to be generated in an investigation,,"Some examples of Project Objectives are Raw sequence reads, Sequence, Analysis, Assembly, Annotation, Variation, Epigenetic markers, expression, maps, phenotype",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0500000,OBI:0001892,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,specification of data to be generated in an investigation,,,,,,Project Objectives,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0200029,mean centering,mean centring,"A mean centering is a data transformation that takes as input an n-dimensional (real) vector, performs a mean calculation on its components, and subtracts the resulting mean from each component of the input.",false,,,http://purl.obolibrary.org/obo/OBI_0200169,,http://purl.obolibrary.org/obo/OBI_0200167,,mean centring,,,,,,,,,,,,,,,"A mean centering is a data transformation that takes as input an n-dimensional (real) vector, performs a mean calculation on its components, and subtracts the resulting mean from each component of the input.",PERSON: Elisabetta Manduchi,,,,,,mean centering,,"This can be used as a normalization method in expression microarray assays. For example, given a two-channel microarray assay, the log ratios of the two channels (M values) can be mean-centered.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200029,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,mean centering,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/IAO_0000584,time sampled measurement data set,experimental time series,A data set that is an aggregate of data recording some measurement at a number of time points. The time series data set is an ordered list of pairs of time measurement data and the corresponding measurement data acquired at that time.,false,,,http://purl.obolibrary.org/obo/IAO_0000100,,,,experimental time series,,,,,,,,,,,,,,,A data set that is an aggregate of data recording some measurement at a number of time points. The time series data set is an ordered list of pairs of time measurement data and the corresponding measurement data acquired at that time.,,,,,,,time sampled measurement data set,,pmid:20604925 - time-lapse live cell microscopy,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000582,,,,,,,,,,,,,,,,IAO:0000584,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,time sampled measurement data set,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0200155,divisive hierarchical clustering,top-down hierarchical clustering,A divisive hierarchical clustering is a hierarchical clustering which starts with a single cluster and then successively splits resulting clusters until only clusters of individual objects remain.,false,,,http://purl.obolibrary.org/obo/OBI_0200042,,,,top-down hierarchical clustering,,,,,,,,,,,,,,,A divisive hierarchical clustering is a hierarchical clustering which starts with a single cluster and then successively splits resulting clusters until only clusters of individual objects remain.,PERSON: Elisabetta Manduchi,,,,,,divisive hierarchical clustering,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200155,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,divisive hierarchical clustering,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/IAO_0000057,contour plot,,,false,,,http://purl.obolibrary.org/obo/IAO_0000038,,,,,,,,,,,,,,,,,,,,OBI_0000246|group:Flow Cytometry community,,,,,generically_dependent_continuants,contour plot,,"Contour plot of SSC-H, FSC-H, and FL1-H.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000002,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000057,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,contour plot,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Allyson Lister|person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0001082,protein separation apparatus,,A device that is used for the separation of proteins.,false,,,http://purl.obolibrary.org/obo/OBI_0000932,,,,,,,,,,,,,,,,,,,A device that is used for the separation of proteins.,PERSON: Erik Segerdell,,,,,,protein separation apparatus,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000372,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001082,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,protein separation apparatus,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001815,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-18 production by T cells,IL-18 release|RNA/DNA detection,An assay of epitope specific interleukin-18 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001380,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-18 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-18 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001815,,,,,,,,,,,,,,,,,,,,,,,,IL-18 release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-18 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0300311,observation design,,observation design is a study design in which subjects are monitored in the absence of any active intervention by experimentalists.,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,observation design is a study design in which subjects are monitored in the absence of any active intervention by experimentalists.,OBI branch derived,,,,,,observation design,,PMID: 12387964.Lancet. 2002 Oct 12;360(9340):1144-9.Deficiency of antibacterial peptides in patients with morbus Kostmann: an observation study.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0300311,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,observation design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0200037,pareto scaling,,A pareto scaling is a data transformation that divides all measurements of a variable by the square root of the standard deviation of that variable.,false,,,http://purl.obolibrary.org/obo/OBI_0200169,,http://purl.obolibrary.org/obo/OBI_0200167,,,,,,,,,,,,,,,,,A pareto scaling is a data transformation that divides all measurements of a variable by the square root of the standard deviation of that variable.,PMID:16762068,,,,,,pareto scaling,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200037,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,pareto scaling,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000797,obsolete_primary structure of protein,,The primary structure of a protein that is completely defined by the set of its amino acid residue parts and the linear order induced by the peptide bonds that hold them together|replaced by SO_0000104 polypeptide,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,The primary structure of a protein that is completely defined by the set of its amino acid residue parts and the linear order induced by the peptide bonds that hold them together,,,,,,,obsolete_primary structure of protein,,SIINFEKL' is the primary structure of a peptide ,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000228,,,,,,,,,,,,,,,,,,OBI:0000797,,,,,,,,,,,,,,,,,,replaced by SO_0000104 polypeptide,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_primary structure of protein,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Bjoern Peters,,
http://purl.obolibrary.org/obo/CL_0000814,mature NK T cell,,A mature alpha-beta T cell of a distinct lineage that bears natural killer markers and a T cell receptor specific for a limited set of ligands. NK T cells have activation and regulatory roles particularly early in an immune response.,false,,,http://purl.obolibrary.org/obo/CL_0000789,,,,,,,,,,,,,,,,,,,A mature alpha-beta T cell of a distinct lineage that bears natural killer markers and a T cell receptor specific for a limited set of ligands. NK T cells have activation and regulatory roles particularly early in an immune response.,,,,,,,mature NK T cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CL:0000814,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/cl.owl,,,,,,,,,,,,,,,,,,,mature NK T cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200116,loess fitting,,"A loess fitting is a curve fitting obtained by localized regression. The latter refers to fitting a polynomial (straight line, quadratic, cubic, etc) to data values within a window covering a fraction of the total number of observations. As the window slides along the axis, a new polynomial is fit to the observations falling within the window. This continues until all points are fit with a local polynomial. The results are then smoothed together to form a curve. The smoothness of loess fits is controlled by a smoothing parameter (often denoted as alpha, usually between 1/4 and 1) and the degree of the polynomial that is fitted by the method (usually denoted by lambda).",false,,,http://purl.obolibrary.org/obo/OBI_0200072,,http://purl.obolibrary.org/obo/OBI_0200174,,,,,,,,,,,,,,,,,"A loess fitting is a curve fitting obtained by localized regression. The latter refers to fitting a polynomial (straight line, quadratic, cubic, etc) to data values within a window covering a fraction of the total number of observations. As the window slides along the axis, a new polynomial is fit to the observations falling within the window. This continues until all points are fit with a local polynomial. The results are then smoothed together to form a curve. The smoothness of loess fits is controlled by a smoothing parameter (often denoted as alpha, usually between 1/4 and 1) and the degree of the polynomial that is fitted by the method (usually denoted by lambda).","ARTICLE: Mathematical details of loess fits are given in Cleveland, William (1993) Visualizing Data. Hobart Press, Summit, New Jersey, pp. 94-101.",,,,,,loess fitting,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200116,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,loess fitting,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Monnie McGee|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000379,mechanical function,,A mechanical function is a function that is realised via mechanical work (through an certain amount of energy transferred by some force).,false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,A mechanical function is a function that is realised via mechanical work (through an certain amount of energy transferred by some force).,http://en.wikipedia.org/wiki/Mechanical_work,,,,,,mechanical function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000379,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,mechanical function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bill Bug|Daniel Schober|Frank Gibson|Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0001077,small-animal image acquisition device,,"A device that is used to image small laboratory animals (e.g., rats and mice) in vivo.",false,,,http://purl.obolibrary.org/obo/OBI_0000398,,,,,,,,,,,,,,,,,,,"A device that is used to image small laboratory animals (e.g., rats and mice) in vivo.",PERSON: Erik Segerdell,,,,,,small-animal image acquisition device,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453|http://purl.obolibrary.org/obo/OBI_0000397,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001077,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,small-animal image acquisition device,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0302899,decapitation,,"decapitation is a process by which the head of a living organism is physically removed from the body, usually resulting in rapid death (in the case of Rhodnius prolixus, it might take a bit longer..)",false,,,http://purl.obolibrary.org/obo/OBI_0000919,,,,,,,,,,,,,,,,,,,"decapitation is a process by which the head of a living organism is physically removed from the body, usually resulting in rapid death (in the case of Rhodnius prolixus, it might take a bit longer..)",OBI-Branch,,,,,,decapitation,,"PMID: 18246869. Loss of cortical function in mice after decapitation, cervical dislocation, potassium chloride injection, and CO2 inhalation. Comp Med. 2007 Dec;57(6):570-",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302899,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,decapitation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000579,Varian UNITY spectrometer,,The predecessor series of the Varian UNITY INOVA spectrometer.,false,,,http://purl.obolibrary.org/obo/OBI_0000611,,,,,,,,,,,,,,,,,NMR instrument,,The predecessor series of the Varian UNITY INOVA spectrometer.,WEB:<http://www.scs.uiuc.edu/NMR/instruments/u400.php>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400237,,,,,,Varian UNITY spectrometer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000579,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Varian UNITY spectrometer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000603,liquid chromatography column,,"A liquid chromatography column is a chromatography column that is used in liquid chromatography, i.e. a column that is provided with a liquid sample mix.",false,,,http://purl.obolibrary.org/obo/OBI_0000038,,,,,,,,,,,,,,,,,,,"A liquid chromatography column is a chromatography column that is used in liquid chromatography, i.e. a column that is provided with a liquid sample mix.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01227,,,,,,liquid chromatography column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000603,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,liquid chromatography column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001817,ELISPOT assay measuring epitope specific interleukin-18 production by T cells,IL-18 release|ELISPOT,An assay of epitope specific interleukin-18 production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001380,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-18 production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific interleukin-18 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001817,,,,,,,,,,,,,,,,,,,,,,,,IL-18 release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific interleukin-18 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001710,in vivo assay measuring B cell epitope specific protection from challenge,protection from challenge|in vivo assay,An efficacy of B cell epitope intervention experiment that uses a protection from challenge in vivo intervention experiment.,false,,,http://purl.obolibrary.org/obo/OBI_0001698,,,,,,,,,,,,,,,,,,,An efficacy of B cell epitope intervention experiment that uses a protection from challenge in vivo intervention experiment.,IEDB,,,,,,in vivo assay measuring B cell epitope specific protection from challenge,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001710,,,,,,,,,,,,,,,,,,,,,,,,protection from challenge|in vivo assay,,,,,,,,,,,,,,,,,,,,,,in vivo assay measuring B cell epitope specific protection from challenge,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/BFO_0000006,spatial region,,,false,,,http://purl.obolibrary.org/obo/BFO_0000141,,,,,,,SpatialRegion,s-region,,,,,,,,,,,,,,,,,"Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional.|BFO 2 Reference: Spatial regions do not participate in processes.",spatial region,A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001]),,,,,,,,,(forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001] |(forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001] ,All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001]),,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000006,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,spatial region,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0400149,protein microarray,,"A protein-microarray is a microarray, ususlly a piece of glass, on which different molecules of protein have been affixed at separate locations in an ordered manner. These are used to identify protein-protein or protein-small molecule interactions.",false,,,http://purl.obolibrary.org/obo/OBI_0400147,,,,,,,,,,,,,,,,,,,"A protein-microarray is a microarray, ususlly a piece of glass, on which different molecules of protein have been affixed at separate locations in an ordered manner. These are used to identify protein-protein or protein-small molecule interactions.",PERSON: Daniel Schober,,,,,,protein microarray,,"The most common protein microarray is the antibody microarray, where antibodies are spotted onto the protein chip and are used as capture molecules to detect proteins from cell lysate solutions.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400149,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,protein microarray,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001490,cytometric bead array measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells,GM-CSF release|cytometric bead array,An assay of epitope specific granulocyte macrophage colony stimulating factor production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001233,,,,,,,,,,,,,,,,,,,An assay of epitope specific granulocyte macrophage colony stimulating factor production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001490,,,,,,,,,,,,,,,,,,,,,,,,GM-CSF release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001345,biological activity assay measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells,CCL4/MIP-1b release|biological activity,A T cell epitope specific cytokine production assay that detects chemokine (C-C motif) ligand 4 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects chemokine (C-C motif) ligand 4 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001345,,,,,,,,,,,,,,,,,,,,,,,,CCL4/MIP-1b release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0002083,enhancer activity detection by reporter gene assay,enhancer reporter gene assay,A reporter gene assay in which expression of a reporter gene is detected that was inserted under the control of an enhancer of interest.,false,,,http://purl.obolibrary.org/obo/OBI_0002082,,,,enhancer reporter gene assay,,,,,,,,,,,,,,,A reporter gene assay in which expression of a reporter gene is detected that was inserted under the control of an enhancer of interest.,"FaceBase, PMID 24614317",,,,,Tracker item: 781,enhancer activity detection by reporter gene assay,,"PMID 19268701: ""we experimentally concatenated up to four enhancers from different genes and used a transgenic mouse assay to compare the in vivo activity of these compound elements with that of the single modules""",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002083,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,enhancer activity detection by reporter gene assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Paul D. Thomas, Yang Chai",,
http://purl.obolibrary.org/obo/OBI_0000235,standard error,,"A quantitative confidence value which is the standard deviations of the sample in a frequency distribution, obtained by dividing the standard deviation by the total number of cases in the frequency distribution.",false,,,http://purl.obolibrary.org/obo/OBI_0000071,,,,,,,,,,,,,,,,,see P-Value,,"A quantitative confidence value which is the standard deviations of the sample in a frequency distribution, obtained by dividing the standard deviation by the total number of cases in the frequency distribution.",group:OBI,,,,,,standard error,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000235,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,standard error,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/IAO_0000032,scalar measurement datum,,"a scalar measurement datum is a measurement datum that is composed of two parts, numerals and a unit label.",false,,,http://purl.obolibrary.org/obo/IAO_0000109,,,,,,,,,,,,,,,,,,,"a scalar measurement datum is a measurement datum that is composed of two parts, numerals and a unit label.",,,,,,"2009-03-16: we decided to keep datum singular in scalar measurement datum, as in
this case we explicitly refer to the singular form|Would write this as: has_part some 'measurement unit label' and has_part some numeral and has_part exactly 2, except for the fact that this won't let us take advantage of OWL reasoning over the numbers. Instead use has measurment value property to represent the same. Use has measurement unit label (subproperty of has_part) so we can easily say that there is only one of them.",scalar measurement datum,,10 feet. 3 ml.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001931,,,,,,,,,IAO:0000032,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,scalar measurement datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot|PERSON: Alan Ruttenberg,,
http://purl.obolibrary.org/obo/IAO_0000593,software library,,A software library is software composed of a collection of software modules and/or software methods in a form that can be statically or dynamically linked to some software application.,false,,,http://purl.obolibrary.org/obo/IAO_0000010,,,,,,,,,,,,,,,,,,,A software library is software composed of a collection of software modules and/or software methods in a form that can be statically or dynamically linked to some software application.,http://code.google.com/p/information-artifact-ontology/issues/detail?id=80,,,,,,software library,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000593,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,software library,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot|PERSON: Michel Dumontier,,
http://purl.obolibrary.org/obo/OBI_0001617,PubMed ID,PMID|PubMed Identifier|Publication Citation,"A CRID symbol that is sufficient to look up a citation from the PubMed, a literature database of life sciences and biomedical information.",false,,,http://purl.obolibrary.org/obo/IAO_0000577,,,,PMID|PubMed Identifier,,,,,,,,,,,,,,,"A CRID symbol that is sufficient to look up a citation from the PubMed, a literature database of life sciences and biomedical information.",Website: http://en.wikipedia.org/wiki/Wikipedia:PMID,,,,,,PubMed ID,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001617,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PubMed ID,,,,,,Publication Citation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000319,material to be added role,,material to be added role is a protocol participant role realized by a material which is added into a material bearing the target of material addition role in a material addition process,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,9 March 09 from discussion with PA branch,,material to be added role is a protocol participant role realized by a material which is added into a material bearing the target of material addition role in a material addition process,OBI,,,,,,material to be added role,,drug added to a buffer contained in a tube; substance injected into an animal;,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000319,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,material to be added role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Role Branch,,
http://purl.obolibrary.org/obo/CHEBI_37333,gadodiamide,,A non-ionic gadolinium chelate having a macrocyclic triamine framework. It is used as a paramagnetic contrast agent in magnetic resonance imaging (MRI).,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,A non-ionic gadolinium chelate having a macrocyclic triamine framework. It is used as a paramagnetic contrast agent in magnetic resonance imaging (MRI).,,,,,,,gadodiamide,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:37333,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,gadodiamide,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0002070,in vivo assay measuring epitope specific proliferation of T cells,proliferation|in vivo assay,A T cell epitope specific proliferation assay that is performed in vivo.,false,,,http://purl.obolibrary.org/obo/OBI_1110131,,,,,,,,,,,,,,,,,,,A T cell epitope specific proliferation assay that is performed in vivo.,IEDB,,,,,,in vivo assay measuring epitope specific proliferation of T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002070,,,,,,,,,,,,,,,,,,,,,,,,proliferation|in vivo assay,,,,,,,,,,,,,,,,,,,,,,in vivo assay measuring epitope specific proliferation of T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/IAO_0000302,author identification,,A textual entity intended to identify a particular author,false,,,http://purl.obolibrary.org/obo/IAO_0000590,,,,,,,,,,,,,,,,,,,A textual entity intended to identify a particular author,,,,,,,author identification,,L. Hunter,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000302,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,author identification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0000522,vial,,A vial is a cylindrical container often made from glass tubing.,false,,,http://purl.obolibrary.org/obo/OBI_0000601,,,,,,,,,,,,,,,,,,,A vial is a cylindrical container often made from glass tubing.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01117,,,,,,vial,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000522,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,vial,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001958,systematic review study design,,"A study design for identifying in the literature prior studies of a pre-determined phenomenon or set of related phenomena according to certain criteria, extracting findings from these studies, and summarizing these findings and/or attempting to draw new conclusions from them which were not justified by any of the individual, prior studies. Many systematic reviews also assess the quality of the studies so reviewed.",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A study design for identifying in the literature prior studies of a pre-determined phenomenon or set of related phenomena according to certain criteria, extracting findings from these studies, and summarizing these findings and/or attempting to draw new conclusions from them which were not justified by any of the individual, prior studies. Many systematic reviews also assess the quality of the studies so reviewed.",,,,,,,systematic review study design,,The effect of moderate gestational alcohol consumption during pregnancy on speech and language outcomes in children: a systematic review. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892059/|Red blood cell transfusion in patients with traumatic brain injury: a systematic review protocol. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090399/,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001958,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,systematic review study design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bill Hogan,,
http://purl.obolibrary.org/obo/OBI_1110022,adaptive immune receptor,,is a receptor produced by cells of the adaptive immune system with the purpose of binding epitopes.,false,,,http://purl.obolibrary.org/obo/GO_0043234,,,,,,,,,,,,,,,,,,,is a receptor produced by cells of the adaptive immune system with the purpose of binding epitopes.,IEDB,,,,,,adaptive immune receptor,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110022,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,adaptive immune receptor,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0200082,longitudinal data analysis,longitudinal data analysis|correlation analysis,Longitudinal analysis is a data transformation used to perform repeated observations of the same items over long periods of time.,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,http://purl.obolibrary.org/obo/OBI_0200196,,longitudinal data analysis|correlation analysis,,,,,,,,,,,,,,,Longitudinal analysis is a data transformation used to perform repeated observations of the same items over long periods of time.,,,,,,,longitudinal data analysis,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200082,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,longitudinal data analysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Tina Boussard|PERSON: James Malone,,
http://purl.obolibrary.org/obo/OBI_0000564,tecmag EAGLE probe,,"The Eagle is a 4 mm 1H/X solid-state MAS probe with a top spinning speed of 18 kHz. Its simple design is robust, reliable and easy to spin. Configurations are available for 200 to 600 MHz wide bore magnets on Tecmag, Bruker, Chemagnetics, JEOL and Varian spectrometers.",false,,,http://purl.obolibrary.org/obo/OBI_0000479,,,,,,,,,,,,,,,,,NMR probe,,"The Eagle is a 4 mm 1H/X solid-state MAS probe with a top spinning speed of 18 kHz. Its simple design is robust, reliable and easy to spin. Configurations are available for 200 to 600 MHz wide bore magnets on Tecmag, Bruker, Chemagnetics, JEOL and Varian spectrometers.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400248,,,,,,tecmag EAGLE probe,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000564,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,tecmag EAGLE probe,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/BFO_0000140,continuant fiat boundary,,"b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])",false,,,http://purl.obolibrary.org/obo/BFO_0000141,,,,,,,ContinuantFiatBoundary,cf-boundary,,,,,,,,,,,"b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])",,,,,,"BFO 2 Reference: In BFO 1.1 the assumption was made that the external surface of a material entity such as a cell could be treated as if it were a boundary in the mathematical sense. The new document propounds the view that when we talk about external surfaces of material objects in this way then we are talking about something fiat. To be dealt with in a future version: fiat boundaries at different levels of granularity.More generally, the focus in discussion of boundaries in BFO 2.0 is now on fiat boundaries, which means: boundaries for which there is no assumption that they coincide with physical discontinuities. The ontology of boundaries becomes more closely allied with the ontology of regions.|BFO 2 Reference: a continuant fiat boundary is a boundary of some material entity (for example: the plane separating the Northern and Southern hemispheres; the North Pole), or it is a boundary of some immaterial entity (for example of some portion of airspace). Three basic kinds of continuant fiat boundary can be distinguished (together with various combination kinds [29|Continuant fiat boundary doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the mereological sum of two-dimensional continuant fiat boundary and a one dimensional continuant fiat boundary that doesn't overlap it. The situation is analogous to temporal and spatial regions.",continuant fiat boundary,,,,,,,,,,(iff (ContinuantFiatBoundary a) (and (ImmaterialEntity a) (exists (b) (and (or (ZeroDimensionalSpatialRegion b) (OneDimensionalSpatialRegion b) (TwoDimensionalSpatialRegion b)) (forall (t) (locatedInAt a b t)))) (not (exists (c t) (and (SpatialRegion c) (continuantPartOfAt c a t)))))) // axiom label in BFO2 CLIF: [029-001] ,Every continuant fiat boundary is located at some spatial region at every time at which it exists,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000140,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,continuant fiat boundary,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0400103,DNA sequencer,,A DNA sequencer is an instrument that determines the order of deoxynucleotides in deoxyribonucleic acid sequences.,false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,A DNA sequencer is an instrument that determines the order of deoxynucleotides in deoxyribonucleic acid sequences.,MO,,,,,,DNA sequencer,,"ABI 377 DNA Sequencer, ABI 310 DNA Sequencer",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400103,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNA sequencer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Trish Whetzel,,
http://purl.obolibrary.org/obo/OBI_0001906,cancer cell line,,An immortal cell line derived from a transformed cell that was part of a malignant tumor.,false,,,http://purl.obolibrary.org/obo/CLO_0009828,,,,,,,,,,,,,,,,,,,An immortal cell line derived from a transformed cell that was part of a malignant tumor.,,,,,,,cancer cell line,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001906,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000867,,,cancer cell line,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001358,post-transcriptional modification design,,"A study design in which a modification of the transcriptome, proteome (not genome) is made, for example RNAi, antibody targeting.|post transcription modification design?
or more clear RNAi design / antibody targeting design?
need to check the use cases",false,,,http://purl.obolibrary.org/obo/OBI_0000115,,,,,,,,,,,,,,,,,,,"A study design in which a modification of the transcriptome, proteome (not genome) is made, for example RNAi, antibody targeting.",MO_392 cellular_modification_design,,,,,,post-transcriptional modification design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000015,,,,,,,,,,,,,,,,OBI:0001358,,,,,,,,,,,,,,,,,,"post transcription modification design?
or more clear RNAi design / antibody targeting design?
need to check the use cases",,,,,,,,,,,,,,,,,,,,,,,,,,,,post-transcriptional modification design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_1110043,cultured adherent cell populaiton,adherent cell culture sample,A mixed cell population that is characterized by its ability to bind to tissue culture flasks or plates. This population typically contains macrophages and other cells capable of playing the antigen presenting cell role.,false,,,http://purl.obolibrary.org/obo/OBI_0100060,,,,adherent cell culture sample,,,,,,,,,,,,,,,A mixed cell population that is characterized by its ability to bind to tissue culture flasks or plates. This population typically contains macrophages and other cells capable of playing the antigen presenting cell role.,IEDB,,,,,"MHB 3-27-13: Following CLO alignment efforts, propose to update definition to read: ""A cultured cell population comprised of cells that are able to grow attached to a solid substrate provided by tissue culture flasks or plates"". The current definition seems to describe a more specific type of adherent culture of immunological origin as needed by IEDB. 

MHB 3-5-13: Need to review axiom on this class in light of clarification that it refers to a cell line sample, and not an entire line. Not every population of adhernet cells is the output of an isolation process.",cultured adherent cell populaiton,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110043,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cultured adherent cell populaiton,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000630,hematology,"blood analysis, haematology",hematology is a process studying blood and blood producing organs relying on a variety of techniques and instruments,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,http://purl.obolibrary.org/obo/OBI_0000441,,"blood analysis, haematology",,,,,,,,,,,,,,,hematology is a process studying blood and blood producing organs relying on a variety of techniques and instruments,OBI branch derived,,,,,,hematology,,"Co-associations between insulin sensitivity and measures of liver function, subclinical inflammation, and hematology. 
Godsland IF, Johnston DG. 
Metabolism. 2008 Sep;57(9):1190-7. 
PMID: 18702943",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000630,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,hematology,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001804,ELISPOT assay measuring epitope specific interleukin-7 production by T cells,IL-7 release|ELISPOT,An assay of epitope specific interleukin-7 production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001587,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-7 production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific interleukin-7 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001804,,,,,,,,,,,,,,,,,,,,,,,,IL-7 release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific interleukin-7 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/PR_000000001,protein,,An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA.,false,,,http://purl.obolibrary.org/obo/CHEBI_16670,,,,,,,,,,,,,,,,,,,An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA.,,,,,,,protein,,antithrombin III is a protein,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PR:000000001,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pr.owl,,,,,,,,,,,,,,,,,,,protein,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0600053,electrophoresis,,a protocol application that uses an electrical potential to move material through a defined matrix in order to separate it by its resistance to movement and its charge,false,,,http://purl.obolibrary.org/obo/OBI_0600014,,http://purl.obolibrary.org/obo/OBI_0000681,,,,,,,,,,,,,,,"Need to define more terms like gel_separation, matrix,centrifugation, and the connection between the force used to separate materials and the medium or barriers.",,a protocol application that uses an electrical potential to move material through a defined matrix in order to separate it by its resistance to movement and its charge,OBI branch derived,,,,,,electrophoresis,,Loading a mixture of proteins into a polyacrylamide gel and the application of an electrical current to the gel to separate the proteins by size and change.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0400140|http://purl.obolibrary.org/obo/OBI_0400142,,,,,,,,,,,,,,,OBI:0600053,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,electrophoresis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Kevin Clancy,,
http://purl.obolibrary.org/obo/OBI_0001550,cell bound MHC binding assay measuring binding of a MHC:ligand complex,qualitative binding|cellular MHC,A MHC binding qualitative binding to ligand assay measuring MHC ligand binding using MHC present on cells.,false,,,http://purl.obolibrary.org/obo/OBI_0002072,,,,,,,,,,,,,,,,,,,A MHC binding qualitative binding to ligand assay measuring MHC ligand binding using MHC present on cells.,IEDB,,,,,,cell bound MHC binding assay measuring binding of a MHC:ligand complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001550,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|cellular MHC,,,,,,,,,,,,,,,,,,,,,,cell bound MHC binding assay measuring binding of a MHC:ligand complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0200178,class discovery objective,unsupervised classification objective|discriminant analysis objective|clustering objective,"A class discovery objective (sometimes called unsupervised classification) is a data transformation objective where the aim is to organize input data  (typically vectors of attributes) into classes, where the number of classes and their specifications are not known a priori. Depending on usage, the class assignment can be definite or probabilistic.",false,,,http://purl.obolibrary.org/obo/OBI_0200166,,,,unsupervised classification objective|discriminant analysis objective|clustering objective,,,,,,,,,,,,,,,"A class discovery objective (sometimes called unsupervised classification) is a data transformation objective where the aim is to organize input data  (typically vectors of attributes) into classes, where the number of classes and their specifications are not known a priori. Depending on usage, the class assignment can be definite or probabilistic.",PERSON: James Malone|PERSON: Elisabetta Manduchi,,,,,,class discovery objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200178,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,class discovery objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0600021,cell fixation,,a protocol application to preserve defined  qualities of cells or tissues (sample) which may otherwise change over time,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,we could generalize this for other input materials,,a protocol application to preserve defined  qualities of cells or tissues (sample) which may otherwise change over time,OBI branch derived,,,,,should include capturing what qualities are being preserved,cell fixation,,http://www.tissuearray.org/CellLinesProtocolforTMA112.pdf; the treatment of CD8+ cells with methanol at -20oC; http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&amp;list_uids=16080188&dopt=AbstractPlus,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600021,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cell fixation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Bjoern Peters,,
http://purl.obolibrary.org/obo/PR_000003745,double-stranded RNA-specific adenosine deaminase,,A protein that is a translation product of the human ADAR gene or a 1:1 ortholog thereof.,false,,,http://purl.obolibrary.org/obo/PR_000000001,,,,,,,,,,,,,,,,,,,A protein that is a translation product of the human ADAR gene or a 1:1 ortholog thereof.,,,,,,,double-stranded RNA-specific adenosine deaminase,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PR:000003745,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pr.owl,,,,,,,,,,,,,,,,,,,double-stranded RNA-specific adenosine deaminase,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000554,gas chromatography oven,,"A gas chromatography oven is an oven with a heated connection between the GC and the MS instrument in a GCMS-analysis, that keeps compounds in the gas phase as they leave the GC oven.",false,,,http://purl.obolibrary.org/obo/OBI_0000542,,,,,,,,,,,,,,,,,gas chromatography equipment,,"A gas chromatography oven is an oven with a heated connection between the GC and the MS instrument in a GCMS-analysis, that keeps compounds in the gas phase as they leave the GC oven.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01039,,,,,,gas chromatography oven,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000554,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,gas chromatography oven,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/CLO_0000578,CLO_0000578,,,false,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CLO:0000578,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0097278,complement-dependent cytotoxicity,,Lysis of a cell resulting from triggering of the complement cascade. An example can be seen with complement activation and subsequent lysis of a bacterial cell as a result of the binding of IgM to the cell surface followed by the binding of complement proteins to that antibody.,false,,,http://purl.obolibrary.org/obo/GO_0001906,,,,,,,,,,,,,,,,,,,Lysis of a cell resulting from triggering of the complement cascade. An example can be seen with complement activation and subsequent lysis of a bacterial cell as a result of the binding of IgM to the cell surface followed by the binding of complement proteins to that antibody.,,,,,,,complement-dependent cytotoxicity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0097278,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,complement-dependent cytotoxicity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/CHEBI_16670,peptide,,"Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc.",false,,,http://purl.obolibrary.org/obo/CHEBI_33839,,,,,,,,,,,,,,,,,,,"Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc.",,,,,,,peptide,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:16670,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,peptide,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OGMS_0000023,phenotype,,A (combination of) quality(ies) of an organism determined by the interaction of its genetic make-up and environment that differentiates specific instances of a species from other instances of the same species.,false,,,http://purl.obolibrary.org/obo/BFO_0000019,,,,,,,,,,,,,,,,,,,A (combination of) quality(ies) of an organism determined by the interaction of its genetic make-up and environment that differentiates specific instances of a species from other instances of the same species.,,,,,,,phenotype,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OGMS:0000023,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ogms.owl,,,,,,,,,,,,,,,,,,,phenotype,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000985,growth condition intervention design,,A study design in which the independent variable is the environmental condition in which the specimen is growing,false,,,http://purl.obolibrary.org/obo/OBI_0000115,,,,,,,,,,,,,,,,,,,A study design in which the independent variable is the environmental condition in which the specimen is growing,MO_588 growth_condition_design,,,,,,growth condition intervention design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000985,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,growth condition intervention design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters,,
http://purl.obolibrary.org/obo/BFO_0000147,zero-dimensional continuant fiat boundary,,,false,,,http://purl.obolibrary.org/obo/BFO_0000140,,,,,,,ZeroDimensionalContinuantFiatBoundary,0d-cf-boundary,,,,,,,,,,,,,,,,,"zero dimension continuant fiat boundaries are not spatial points. Considering the example 'the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet' : There are many frames in which that point is zooming through many points in space. Whereas, no matter what the frame, the quadripoint is always in the same relation to the boundaries of Colorado, Utah, New Mexico, and Arizona.",zero-dimensional continuant fiat boundary,a zero-dimensional continuant fiat boundary is a fiat point whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [031-001]),"the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet|the geographic North Pole|the point of origin of some spatial coordinate system.",,,,,,,,(iff (ZeroDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (ZeroDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [031-001] ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000147,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,zero-dimensional continuant fiat boundary,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://usefulinc.com/ns/doap#SVNRepository,SVNRepository,,,false,,,http://www.w3.org/2002/07/owl#Thing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,doap:SVNRepository,,,,,,,,,,,,,,,,,,,http://usefulinc.com/ns/doap,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000372,material separation function,,A material separation function is a function that increases the resolution between two or more material entities. The  to distinction between the entities is usually based on some associated physical quality.,false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,A material separation function is a function that increases the resolution between two or more material entities. The  to distinction between the entities is usually based on some associated physical quality.,,,,,,,material separation function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000372,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,material separation function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bill Bug|Daniel Schober|Frank Gibson|Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0001838,ELISPOT assay measuring epitope specific interleukin-16 production by T cells,IL-16 release|ELISPOT,An assay of epitope specific interleukin-16 production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001280,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-16 production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific interleukin-16 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001838,,,,,,,,,,,,,,,,,,,,,,,,IL-16 release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific interleukin-16 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000227,data encoding,,a documenting process to encode an information entity into a digital document,false,,,http://purl.obolibrary.org/obo/IAO_0000572,,,,,,,,,,,,,,,,,We (protocol application branch) placed this term because it kept getting bounced from data transformation and DENRIE,,a documenting process to encode an information entity into a digital document,OBI branch derived,,,,,,data encoding,,"storage of measurement results from an assay into a text file, such as",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000227,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,data encoding,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0001545,intracellular cytokine staining assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells,CCL3/MIP-1a release|ICS,An assay of epitope specific macrophage inflammatory protein-1 alpha production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001333,,,,,,,,,,,,,,,,,,,An assay of epitope specific macrophage inflammatory protein-1 alpha production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001545,,,,,,,,,,,,,,,,,,,,,,,,CCL3/MIP-1a release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001535,epitope specific interleukin-7 production by T cells,,A process of interleukin-7 production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/OBI_0001193|http://purl.obolibrary.org/obo/GO_0032636,,,,,,,,,,,,,,,,,Date: 2011-11-10; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mappings: assay_mappings.owl,,A process of interleukin-7 production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific interleukin-7 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001535,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific interleukin-7 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000665,obsolete intracellular cytokine staining assay,ICCS| ICS|intracellular cytokine staining (ICS),"The measurement of cytokines within the cytoplasm of a cell by permeabilizing the cell membrane to allow entry of specific antibodies, and counting the stained cells using a flow cytometer.",true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,ICCS| ICS,,,,,,,,,,,,,,,"The measurement of cytokines within the cytoplasm of a cell by permeabilizing the cell membrane to allow entry of specific antibodies, and counting the stained cells using a flow cytometer.",IEDB,,,,,,obsolete intracellular cytokine staining assay,,Permeabilizing T cells and staining them with fluorescent labeled anti-IFN-gamma antibodies,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000227,,,,,,,,,,,,,,,,,,OBI:0000665,,,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining (ICS),,,,,,,,,,,,,,,,,,,,,,obsolete intracellular cytokine staining assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,http://purl.obolibrary.org/obo/OBI_0000916,
http://purl.obolibrary.org/obo/IAO_0000028,symbol,,An information content entity that is a mark(s) or character(s) used as a conventional representation of another entity.,false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,,,,,,,,,,,,,,,,An information content entity that is a mark(s) or character(s) used as a conventional representation of another entity.,based on Oxford English Dictionary,,,,,"20091104, MC: this needs work and will most probably change|2014-03-31: We would like to have a deeper analysis of 'mark' and 'sign' in the future (see https://code.google.com/p/information-artifact-ontology/issues/detail?id=154).",symbol,,"a serial number such as ""12324X""|a stop sign|a written proper name such as ""OBI""",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000028,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,symbol,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Jonathan Rees|PERSON: James A. Overton,,
http://purl.obolibrary.org/obo/OBI_0001157,age since hatching measurement datum,,"An age measurement datum that is the result of the measurement of the age of an organism since hatching, the process of emergence from an egg.",false,,,http://purl.obolibrary.org/obo/OBI_0001167,,,,,,,,,,,,,,,,,,,"An age measurement datum that is the result of the measurement of the age of an organism since hatching, the process of emergence from an egg.",MO_745 hatching,,,,,,age since hatching measurement datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001157,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,age since hatching measurement datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001425,protein binding site identification design,,A study design that investigates protein binding sites on nucleic acids.,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,A study design that investigates protein binding sites on nucleic acids.,MO_933 binding_site_identification_design,,,,,,protein binding site identification design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001425,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,protein binding site identification design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001063,automatic staining machine,,A device that is used to automatically stain tissue sections on slides or tissue specimens.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A device that is used to automatically stain tissue sections on slides or tissue specimens.,PERSON: Erik Segerdell,,,,,,automatic staining machine,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000379|http://purl.obolibrary.org/obo/OBI_0000961,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001063,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,automatic staining machine,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001377,organism status comparison design,,A study design that compares samples from live and dead organisms.,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,A study design that compares samples from live and dead organisms.,MO_841 organism_status_design,,,,,,organism status comparison design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000015,,,,,,,,,,,,,,,,OBI:0001377,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,organism status comparison design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0400079,optical filter,,"An optical filter is an optical subsystem that selectively transmits light having certain properties (often, a particular range of wavelengths, that is, range of colours of light), while blocking the remainder. They are commonly used in photography, in many optical instruments, and to colour stage lighting Optical filters can be arranged to segregate and collect light by wave length.",false,,,http://purl.obolibrary.org/obo/OBI_0000932,,,,,,,,,,,,,,,,,,,"An optical filter is an optical subsystem that selectively transmits light having certain properties (often, a particular range of wavelengths, that is, range of colours of light), while blocking the remainder. They are commonly used in photography, in many optical instruments, and to colour stage lighting Optical filters can be arranged to segregate and collect light by wave length.",http://en.wikipedia.org/wiki/Optical_filter,,,,,,optical filter,,"720 LP filter, 580/30 BP filter",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000378,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400079,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,optical filter,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/BFO_0000023,role,,"A realizable entity  the manifestation of which brings about some result or end that is not essential to a continuant  in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant  in some kinds of natural, social or institutional contexts.",false,,,http://purl.obolibrary.org/obo/BFO_0000017,,,,,,,Role,role,,,,,,,,,,,"A realizable entity  the manifestation of which brings about some result or end that is not essential to a continuant  in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant  in some kinds of natural, social or institutional contexts.",,,,,,"BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role & c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals –  professor, sergeant, nurse – only during certain phases in their lives.",role,"b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])","the role of a stone in marking a property boundary|the priest role|the student role|the role of subject in a clinical trial|the role of a boundary to demarcate two neighboring administrative territories|John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married.|the role of a building in serving as a military target",,,,,,,,(forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000023,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001827,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells,CCL1/TCA-3 release|RNA/DNA detection,An assay of epitope specific chemokine (C-C motif) ligand 1 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001276,,,,,,,,,,,,,,,,,,,An assay of epitope specific chemokine (C-C motif) ligand 1 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001827,,,,,,,,,,,,,,,,,,,,,,,,CCL1/TCA-3 release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001198,biological activity assay measuring epitope specific interleukin-27 production by T cells,IL-27 release|biological activity,A T cell epitope specific cytokine production assay that detects interleukin-27 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects interleukin-27 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific interleukin-27 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001198,,,,,,,,,,,,,,,,,,,,,,,,IL-27 release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific interleukin-27 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001104,analytical balance,,A balance with weighing pan(s) inside a transparent enclosure that is used to measure mass to a very high degree of precision and accuracy.,false,,,http://purl.obolibrary.org/obo/OBI_0001135,,,,,,,,,,,,,,,,,,,A balance with weighing pan(s) inside a transparent enclosure that is used to measure mass to a very high degree of precision and accuracy.,http://en.wikipedia.org/wiki/Weighing_scale,,,,,,analytical balance,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001104,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,analytical balance,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001698,biological activity assay measuring B cell epitope specific in vivo activity,in vivo activity|biological activity,A B cell epitope dependent biological activity determination assay that uses an in vivo intervention experiment.,false,,,http://purl.obolibrary.org/obo/OBI_0001706,,,,,,,,,,,,,,,,,,,A B cell epitope dependent biological activity determination assay that uses an in vivo intervention experiment.,IEDB,,,,,,biological activity assay measuring B cell epitope specific in vivo activity,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001698,,,,,,,,,,,,,,,,,,,,,,,,in vivo activity|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring B cell epitope specific in vivo activity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/CHEBI_28619,acrylamide,,A member of the class of acrylamides that results from the formal condensation of acrylic acid with ammonia.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,A member of the class of acrylamides that results from the formal condensation of acrylic acid with ammonia.,,,,,,,acrylamide,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:28619,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,acrylamide,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000840,unblinding process,,The part of the study execution in which the subjects are told what study arm they are in and in which the investigators are told which subjects are in which trials,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,,The part of the study execution in which the subjects are told what study arm they are in and in which the investigators are told which subjects are in which trials,,,,,,,unblinding process,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000840,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,unblinding process,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/CHEBI_51760,Alexa Fluor 546,,An organic heteropentacyclic compound that has formula C44H46Cl3N4NaO14S3.,false,,,http://purl.obolibrary.org/obo/REO_0000280,,,,,,,,,,,,,,,,,,,An organic heteropentacyclic compound that has formula C44H46Cl3N4NaO14S3.,,,,,,,Alexa Fluor 546,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/REO_0000171,,,,,,,,,,,,CHEBI:51760,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,Alexa Fluor 546,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001739,surface plasmon resonance assay measuring the off rate [koff] of a B cell epitope:antibody complex,off rate|surface plasmon resonance (SPR)|1/s,A B cell epitope binding off rate measurement (koff) determination assay that uses a surface plasmon resonance assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001723,,,,,,,,,,,,,,,,,,,A B cell epitope binding off rate measurement (koff) determination assay that uses a surface plasmon resonance assay.,IEDB,,,,,,surface plasmon resonance assay measuring the off rate [koff] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001739,,,,,,,,,,,,,,,,,,,,,,,,off rate|surface plasmon resonance (SPR)|1/s,,,,,,,,,,,,,,,,,,,,,,surface plasmon resonance assay measuring the off rate [koff] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000807,presentation of stimulus,stimulation of organism,a planned process in which an organism is exposed to some stimulus with the intent to invoke an action,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,stimulation of organism,,,,,,,,,,,,,,,a planned process in which an organism is exposed to some stimulus with the intent to invoke an action,"Helen Parkinson, Jessica Turner, Dirk Derom",,,,,,presentation of stimulus,,The presentation of a flashing light to a monkey during reward training,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000807,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,presentation of stimulus,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Helen Parkinson, Jessica Turner, Dirk Derom",,
http://purl.obolibrary.org/obo/OBI_0400140,gel tank,electrophoresis unit|electrophoresis box,a device which holds a gel and running buffers to allow electrophoresis to be performed. A gel tank has the function to contain and to control the contained environment and transfer energy from an energy supply through the running buffers to the gel matrix and the material with charged molecules in an electric field across a porous matrix or medium with the objective to separate the charged molecules.,false,,,http://purl.obolibrary.org/obo/OBI_0000967|http://purl.obolibrary.org/obo/OBI_0001034,,,,electrophoresis unit|electrophoresis box,,,,,,,,,,,,,,,a device which holds a gel and running buffers to allow electrophoresis to be performed. A gel tank has the function to contain and to control the contained environment and transfer energy from an energy supply through the running buffers to the gel matrix and the material with charged molecules in an electric field across a porous matrix or medium with the objective to separate the charged molecules.,sep:00095,,,,,,gel tank,,"CHEF gel box, slab gel box, capillary electrophoresis",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000370|http://purl.obolibrary.org/obo/OBI_0000401,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,gel tank,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Kevin Clancy|Person:Frank Gibson,,
http://purl.obolibrary.org/obo/OBI_0000395,signal amplification function,,"A signal amplification function is a signal conversion function to inject energy into an input signal so as to produce an output signal with increased differential magnitude while also seeking to minimize increases in the signal to noise ratio. For example, to produce a 0.1 KW output signal from a 1 mW RMS input signal.",false,,,http://purl.obolibrary.org/obo/OBI_0000393,,,,,,,,,,,,,,,,,,,"A signal amplification function is a signal conversion function to inject energy into an input signal so as to produce an output signal with increased differential magnitude while also seeking to minimize increases in the signal to noise ratio. For example, to produce a 0.1 KW output signal from a 1 mW RMS input signal.",,,,,,,signal amplification function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000395,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,signal amplification function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bill Bug|Daniel Schober|Frank Gibson|Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0100046,phosphate buffered saline solution,PBS buffer,"Phosphate buffered saline (abbreviated PBS) is a buffer solution commonly used in biochemistry. It is a salty solution containing sodium chloride, sodium phosphate and in some preparations potassium chloride and potassium phosphate. The buffer helps to maintain a constant pH. The concentration usually matches the human body (isotonic).",false,,,http://purl.obolibrary.org/obo/OBI_0302729,,,,PBS buffer,,,,,,,,,,,,,,,"Phosphate buffered saline (abbreviated PBS) is a buffer solution commonly used in biochemistry. It is a salty solution containing sodium chloride, sodium phosphate and in some preparations potassium chloride and potassium phosphate. The buffer helps to maintain a constant pH. The concentration usually matches the human body (isotonic).",WEB: http://en.wikipedia.org/wiki/Phosphate_buffered_saline,,,,,,phosphate buffered saline solution,,PMID: 16279733.Dent Mater J. 2005 Sep;24(3):414-21.PBS buffer solutions with different pH values can change porosity of DNA-chitosan complexes.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0302731,,,,,,,,,,,,OBI:0100046,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,phosphate buffered saline solution,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Tina Boussard|PERSON: Melanie Courtot|PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0600019,non-specific labeling,,The addition of a reagent labeling the entire input biomaterial enabling future detection of the output biomaterial,false,,,http://purl.obolibrary.org/obo/OBI_0600038,,,,,,,,,,,,,,,,,"definition blessed by Allyson, Bjoern, Jay & Randi",,The addition of a reagent labeling the entire input biomaterial enabling future detection of the output biomaterial,OBI branch derived,,,,,,non-specific labeling,,"The addition of phycoerytherin label to an anti-CD8 antibody, to label all antibodies.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600019,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,non-specific labeling,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0000463,column chromatography detector,,"There is a wide range of detectors available for both GC and LC each having their own particular areas of application. In general the more catholic the response, the less sensitive the detector and the most sensitive detectors are those that have a specific response. The performance of all detectors should be properly specified so that the user can determine which is most suitable for a specific application. Such specifications are also essential to compare the performance of different detectors supplied by alternative instrument manufactures. Detector specifications should be presented in a standard form and in standard units, so that detectors can be compared that function on widely different principles.",false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,"chromatography detector, defined class/xps",,"There is a wide range of detectors available for both GC and LC each having their own particular areas of application. In general the more catholic the response, the less sensitive the detector and the most sensitive detectors are those that have a specific response. The performance of all detectors should be properly specified so that the user can determine which is most suitable for a specific application. Such specifications are also essential to compare the performance of different detectors supplied by alternative instrument manufactures. Detector specifications should be presented in a standard form and in standard units, so that detectors can be compared that function on widely different principles.",WEB:<http://www.chromatography-online.org/Principles/Basic-Chromatograph/Detector/rs56.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01077,,,,,,column chromatography detector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000463,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,column chromatography detector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_9999994,chromium release assay,,An in vitro cell killing assay in which radioactive chromium is absorbed by cells and released into supernatant when the cells die. The amount of radioactivity measured in the supernatant is a proxy for the number of cells that have died.,false,,,http://purl.obolibrary.org/obo/OBI_0000903,,,,,,,,,,,,,,,,,,,An in vitro cell killing assay in which radioactive chromium is absorbed by cells and released into supernatant when the cells die. The amount of radioactivity measured in the supernatant is a proxy for the number of cells that have died.,IEDB,,,,,,chromium release assay,,"Autologous EBV-transformed B-LCL were used as target cells for the influenza virus-specific CTL assays. Equal volumes of target and effector cells were added to triplicate wells of 96-well tissue culture plates, and 1:2 serial dilutions of effectors were made, producing effector-to-target (E:T) ratios of 100:1, 50:1, 25:1, and 12.5:1. After a 4-h incubation of the effector cells with the target cells, supernatants were collected following brief centrifugation and transferred to polystyrene tubes to be counted with the LKB 1272 Clinigamma counter (Wallac). Percent specific killing was determined with the following equation: (experimental 51Cr release - spontaneous 51Cr release)/(maximum 51Cr release - spontaneous 51Cr release) x 100.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000201,,,,,,,,,,,,,,,,OBI:9999994,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,chromium release assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PlanAndPlannedProcess Branch, IEDB",,
http://purl.obolibrary.org/obo/OBI_0001782,detection of specific nucleic acids with complementary probes assay measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells,CCL9/MIP-1g release|RNA/DNA detection,An assay of epitope specific macrophage inflammatory protein-1 gamma production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001456,,,,,,,,,,,,,,,,,,,An assay of epitope specific macrophage inflammatory protein-1 gamma production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001782,,,,,,,,,,,,,,,,,,,,,,,,CCL9/MIP-1g release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000498,NMR tube washing system,,An automatic cleaning system for NMR tubes that removes previous probe and sample residues in order to allow for tube recycling.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,NMR instrument,,An automatic cleaning system for NMR tubes that removes previous probe and sample residues in order to allow for tube recycling.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400204,,,,,,NMR tube washing system,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000498,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NMR tube washing system,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001135,balance,,A measuring instrument that is used to determine the weight or mass of an object.,false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,A measuring instrument that is used to determine the weight or mass of an object.,http://en.wikipedia.org/wiki/Weighing_scale,,,,,,balance,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453|http://purl.obolibrary.org/obo/OBI_0000379,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001135,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,balance,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0200188,cross validation objective,rotation estimation objective,"A cross validation objective is a data transformation objective in which the aim is to partition a sample of data into subsets such that the analysis is initially performed on a single subset, while the other subset(s) are retained for subsequent use in confirming and validating the initial analysis.",false,,,http://purl.obolibrary.org/obo/OBI_0200172,,,,rotation estimation objective,,,,,,,,,,,,,,,"A cross validation objective is a data transformation objective in which the aim is to partition a sample of data into subsets such that the analysis is initially performed on a single subset, while the other subset(s) are retained for subsequent use in confirming and validating the initial analysis.",WEB: http://en.wikipedia.org/wiki/Cross_validation,,,,,,cross validation objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200188,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cross validation objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0001268,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-12 production by T cells,IL-12 release|RNA/DNA detection,An assay of epitope specific interleukin-12 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001391,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-12 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-12 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001268,,,,,,,,,,,,,,,,,,,,,,,,IL-12 release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-12 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000832,measurement device,,A device in which a measure function inheres.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A device in which a measure function inheres.,OBI,,,,,,measurement device,,"A ruler, a microarray scanner, a Geiger counter.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000832,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,measurement device,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP:OBI Philly workshop,,
http://purl.obolibrary.org/obo/OBI_0001562,intracellular cytokine staining assay measuring epitope specific interleukin-17F production by T cells,IL-17F release|ICS,A T cell epitope specific interleukin-17F production assay that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_1110178|http://purl.obolibrary.org/obo/OBI_0001772,,,,,,,,,,,,,,,,,,,A T cell epitope specific interleukin-17F production assay that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-17F production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001562,,,,,,,,,,,,,,,,,,,,,,,,IL-17F release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-17F production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001478,mass spectrometry assay measuring MHC ligand processing and presentation,ligand presentation|mass spectrometry,A MHC ligand processing and presentation assay that uses a mass spectrometry assay to identify eluted ligands,false,,,http://purl.obolibrary.org/obo/OBI_1110125,,,,,,,,,,,,,,,,,,,A MHC ligand processing and presentation assay that uses a mass spectrometry assay to identify eluted ligands,IEDB,,,,,,mass spectrometry assay measuring MHC ligand processing and presentation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001478,,,,,,,,,,,,,,,,,,,,,,,,ligand presentation|mass spectrometry,,,,,,,,,,,,,,,,,,,,,,mass spectrometry assay measuring MHC ligand processing and presentation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000592,chromatography detector filter,,An optical filter that is used to obtain monochromatic light of a defined wavelength from detector lamps.,false,,,http://purl.obolibrary.org/obo/OBI_0000601,,,,,,,,,,,,,,,,,,,An optical filter that is used to obtain monochromatic light of a defined wavelength from detector lamps.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01121,,,,,,chromatography detector filter,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000592,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,chromatography detector filter,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001351,epitope specific tumor necrosis factor superfamily cytokine production by T cells,,A process of tumor necrosis factor superfamily cytokine production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/OBI_0001193|http://purl.obolibrary.org/obo/GO_0071706,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of tumor necrosis factor superfamily cytokine production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific tumor necrosis factor superfamily cytokine production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001351,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific tumor necrosis factor superfamily cytokine production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_1110206,epitope specific TNF release by T cells,,A biological process where T cells produce TNF resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/OBI_0001351|http://purl.obolibrary.org/obo/GO_0032640,,,,,,,,,,,,,,,,,,,A biological process where T cells produce TNF resulting from the recognition of a T cell epitope.,IEDB,,,,,,epitope specific TNF release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110206,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific TNF release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0400037,FACS Canto,,"A FACS_Canto is a flow_cytometer_analyser manufactured by Becton Dickinson. It features digital electronics, a solid state 488 nm, and a HeNe 633 nm lasers, and filters and PMTs for collecting up to 6 fluorescent parameters. The FACS_Canto is an analyser usually used in clinical applications.",false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,,,,,,,,,,,,,,,,"A FACS_Canto is a flow_cytometer_analyser manufactured by Becton Dickinson. It features digital electronics, a solid state 488 nm, and a HeNe 633 nm lasers, and filters and PMTs for collecting up to 6 fluorescent parameters. The FACS_Canto is an analyser usually used in clinical applications.",http://www.bdbiosciences.com/pdfs/brochures/23-8742-00.pdf,,,,,,FACS Canto,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400037,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,FACS Canto,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0001538,training service,,"A service  in which the service provider offers educational materials or events, such as courses, workshops or graduate programs, to the service consumer.",false,,,http://purl.obolibrary.org/obo/OBI_0001173,,,,,,,,,,,,,,,,,,,"A service  in which the service provider offers educational materials or events, such as courses, workshops or graduate programs, to the service consumer.",PERSON: Matthew Brush,,,,,,training service,,A service that offers training for a specific instrument or technique. A course to learn how to use a microscope,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000939,,,,,,,,,,,,,,,,OBI:0001538,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,training service,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Carlo Torniai|PERSON: Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_0000671,sample from organism,,a material obtained from an organism in order to be a representative of the whole,false,,,http://purl.obolibrary.org/obo/OBI_0001479|http://purl.obolibrary.org/obo/OBI_0000747,,,,,,,,,,,,,,,,,,,a material obtained from an organism in order to be a representative of the whole,,,http://purl.obolibrary.org/obo/CARO_0001008,,,"we need to work on this: Is taking a urine sample a material separation process? If not, we will need to specify what 'taking a sample from organism' entails. We can argue that the objective to obtain a urine sample from a patient is enough to call it a material separation process, but it could dilute what material separation was supposed to be about.|5/29: This is a helper class for now",sample from organism,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000002,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000671,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sample from organism,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001455,ELISPOT assay measuring epitope specific interleukin-5 production by T cells,IL-5 release|ELISPOT,An assay of epitope specific interleukin-5 production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001230,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-5 production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific interleukin-5 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001455,,,,,,,,,,,,,,,,,,,,,,,,IL-5 release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific interleukin-5 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000420,obsolete_trypsinized material,,A material entity that has undergone a process of digestion with trypsin,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,Test Class: to evaluate OBI design pattern,,A material entity that has undergone a process of digestion with trypsin,,,,,,"decided to be deprecated on Aug 2, 2010 dev call",obsolete_trypsinized material,,A trypsinized suspension of cells,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000002,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,OBI:0000420,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_trypsinized material,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_1110019,pathogen release in laboratory accident,,"a process in which a an infectious agent maintained in a laboratory setting is not contained as planned, leading to potential exposure of human beings to the agent",false,,,http://purl.obolibrary.org/obo/OBI_1110111,,,,,,,,,,,,,,,,,,,"a process in which a an infectious agent maintained in a laboratory setting is not contained as planned, leading to potential exposure of human beings to the agent",IEDB,,,,,,pathogen release in laboratory accident,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110019,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,pathogen release in laboratory accident,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000674,center value,median,A data item that is produced as the output of a center calculation data transformation and represents the center value of the input data.,false,,,http://purl.obolibrary.org/obo/IAO_0000027,,,,median,,,,,,,,,,,,,,,A data item that is produced as the output of a center calculation data transformation and represents the center value of the input data.,,,,,,,center value,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000674,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,center value,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: James Malone|PERSON: Monnie McGee,,
http://usefulinc.com/ns/doap#Version,Version,,,false,,,http://www.w3.org/2002/07/owl#Thing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,doap:Version,,,,,,,,,,,,,,,,,,,http://usefulinc.com/ns/doap,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000515,chromatofocusing column,,A chromatofocusing column is a chromatography column in which a resin is equilibrated at one pH and eluted at a second pH. The use of a weak ion-exchange resin causes a pH gradient to be formed at the solvent front owing to the buffering action of the resin. This pH gradient in turn leads to an ordering of proteins by isoelectric point. Molecules of charge sign opposite the resin bind; those of charge sign like the resin do not bind.,false,,,http://purl.obolibrary.org/obo/OBI_0000038,,,,,,,,,,,,,,,,,,,A chromatofocusing column is a chromatography column in which a resin is equilibrated at one pH and eluted at a second pH. The use of a weak ion-exchange resin causes a pH gradient to be formed at the solvent front owing to the buffering action of the resin. This pH gradient in turn leads to an ordering of proteins by isoelectric point. Molecules of charge sign opposite the resin bind; those of charge sign like the resin do not bind.,WEB:<http://www.bioprocessintl.com/default.asp?page=glossary&TopicID=1>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01209,,,,,,chromatofocusing column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000515,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,chromatofocusing column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/GO_0002517,T cell tolerance induction,,A process involving any mechanism for tolerance induction in T cells.,false,,,http://purl.obolibrary.org/obo/GO_0002507,,,,,,,,,,,,,,,,,,,A process involving any mechanism for tolerance induction in T cells.,,,,,,,T cell tolerance induction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0002517,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,T cell tolerance induction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0002514,B cell tolerance induction,,A process involving any mechanism for tolerance induction in B cells.,false,,,http://purl.obolibrary.org/obo/GO_0002507,,,,,,,,,,,,,,,,,,,A process involving any mechanism for tolerance induction in B cells.,,,,,,,B cell tolerance induction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0002514,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,B cell tolerance induction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000593,cation trap column,,A cation trap column is a trap column and ion-exchange column which contains anionic cation-exchange resins.,false,,,http://purl.obolibrary.org/obo/OBI_0000518,,,,,,,,,,,,,,,,,,,A cation trap column is a trap column and ion-exchange column which contains anionic cation-exchange resins.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01278,,,,,,cation trap column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000593,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cation trap column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000397,image acquisition function,,An image acquisition function is a function to acquire an image of a material,false,,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,An image acquisition function is a function to acquire an image of a material,,,,,,,image acquisition function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000397,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000398,,,,,,,,,,,,,,,,,image acquisition function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Frank Gibson,,
http://purl.obolibrary.org/obo/IAO_0000575,associating information with a centrally registered identifier in its registry,associating information with a CRID in the CRID registry,A planned process in which a CRID registry associates an information content entity with a CRID symbol,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,associating information with a CRID in the CRID registry,,,,,,,,,,,,,,,A planned process in which a CRID registry associates an information content entity with a CRID symbol,,,,,,,associating information with a centrally registered identifier in its registry,,Articles in Pubmed are reviewed by curators who add MESH terms to the Pubmed records in order to categorize them better and improve the ability to search for them. ,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000579,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000577|http://purl.obolibrary.org/obo/IAO_0000030,,,,IAO:0000575,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,associating information with a centrally registered identifier in its registry,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0000963,categorical label,,A label that is part of a categorical datum and that indicates the value of the data item on the categorical scale.,false,,,http://purl.obolibrary.org/obo/IAO_0000009,,,,,,,,,,,,,,,,,,,A label that is part of a categorical datum and that indicates the value of the data item on the categorical scale.,Bjoern Peters,,,,,,categorical label,,"The labels 'positive' vs. 'negative', or 'left handed', 'right handed', 'ambidexterous', or 'strongly binding', 'weakly binding' , 'not binding', or '+++', '++', '+', '-' etc. form scales of categorical labels. ",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000963,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,categorical label,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000508,column jacket,,A column jacket is a piece of column chromatography equipment that covers a column in order to ensure thermoisolation and create a controllable thermostatic microenvironment.,false,,,http://purl.obolibrary.org/obo/OBI_0000048,,,,,,,,,,,,,,,,,chromatography device,,A column jacket is a piece of column chromatography equipment that covers a column in order to ensure thermoisolation and create a controllable thermostatic microenvironment.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01276,,,,,,column jacket,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000508,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,column jacket,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000025,reference substance role,reference substance,a role inhering in a material entity that is realized when  characteristics or responses elicited by the substance are used for comparison or reference.,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,reference substance,,,,,,,,,,,,,,,a role inhering in a material entity that is realized when  characteristics or responses elicited by the substance are used for comparison or reference.,OBI,,,,,,reference substance role,,"Calibration standard, positive control substance, vehicle   Good Laboratory Practices: Questions and Answers - Test Control and Reference Substance Characterization  http://www.epa.gov/enforcement/monitoring/programs/fifra/glpqanda-character.html",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000025,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,reference substance role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0001115,ELISA microplate washer,,A microplate washer that is used for enzyme-linked immunosorbent assays (ELISA).,false,,,http://purl.obolibrary.org/obo/OBI_0001113,,,,,,,,,,,,,,,,,,,A microplate washer that is used for enzyme-linked immunosorbent assays (ELISA).,PERSON: Erik Segerdell,,,,,,ELISA microplate washer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001115,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ELISA microplate washer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/CL_0000789,alpha-beta T cell,,A T cell that expresses an alpha-beta T cell receptor complex.,false,,,http://purl.obolibrary.org/obo/CL_0000084,,,,,,,,,,,,,,,,,,,A T cell that expresses an alpha-beta T cell receptor complex.,,,,,,,alpha-beta T cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CL:0000789,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/cl.owl,,,,,,,,,,,,,,,,,,,alpha-beta T cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/CL_0000786,plasma cell,,"A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin.",false,,,http://purl.obolibrary.org/obo/CL_0000236,,,,,,,,,,,,,,,,,,,"A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin.",,,,,,,plasma cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CL:0000786,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/cl.owl,,,,,,,,,,,,,,,,,,,plasma cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001197,comparative genome hybridization by array design,,A study design that detects genomic copy number variations using microarray technology.,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,A study design that detects genomic copy number variations using microarray technology.,MO_856 comparative_genome_hybridization_design,,,,,,comparative genome hybridization by array design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000131,,,,,,,,,,,,,,,,OBI:0001197,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,comparative genome hybridization by array design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/PATO_0000146,temperature,,A physical quality of the thermal energy of a system.,false,,,http://purl.obolibrary.org/obo/PATO_0001237,,,,,,,,,,,,,,,,,,,A physical quality of the thermal energy of a system.,,,,,,,temperature,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0000146,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,temperature,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001281,ELISA measuring epitope specific IP-10 production by T cells,CXCL10/IP-10 release|ELISA,An assay of epitope specific IP-10 production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001308,,,,,,,,,,,,,,,,,,,An assay of epitope specific IP-10 production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific IP-10 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001281,,,,,,,,,,,,,,,,,,,,,,,,CXCL10/IP-10 release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific IP-10 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0200123,skewness calculation,,A skewness calculation is a descriptive statistics calculation defined as a parameter that describes how much a distribution (or a data set) varies from a bell-shaped curve.  See http://www.riskglossary.com/link/skewness.htm for details.  It is also known as the third central moment,false,,,http://purl.obolibrary.org/obo/OBI_0200184|http://purl.obolibrary.org/obo/OBI_0200181,,http://purl.obolibrary.org/obo/OBI_0200078,,,,,,,,,,,,,,,From Monnie's file comments - need to add moment calculation role but they doesn't exist yet - (editor note added by James Jan 2008),,A skewness calculation is a descriptive statistics calculation defined as a parameter that describes how much a distribution (or a data set) varies from a bell-shaped curve.  See http://www.riskglossary.com/link/skewness.htm for details.  It is also known as the third central moment,WEB: http://www.riskglossary.com/link/skewness.htm,,,,,,skewness calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,skewness calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Monnie McGee,,
http://purl.obolibrary.org/obo/OBI_0000627,quaternary pump system,,A pump system that pump and mix up to four different solvents in parallel.,false,,,http://purl.obolibrary.org/obo/OBI_0000589,,,,,,,,,,,,,,,,,,,A pump system that pump and mix up to four different solvents in parallel.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01047,,,,,,quaternary pump system,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000627,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,quaternary pump system,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000862,nuclear RNA extract,,"A RNA extract that is the output of an extraction process in which RNA molecules found in the nucleus, including mRNA precursors (pre-mRNA), are extracted.",false,,,http://purl.obolibrary.org/obo/OBI_0000880,,,,,,,,,,,,,,,,,,,"A RNA extract that is the output of an extraction process in which RNA molecules found in the nucleus, including mRNA precursors (pre-mRNA), are extracted.",UPenn Group,,,,,,nuclear RNA extract,,Isolation and purification of nuclear RNA from animal cells using Norgen Bioteck corp. cytoplasmic and nuclear RNA purification kit (http://www.norgenbiotek.com/display-product.php?ID=30),,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000862,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000888,,,nuclear RNA extract,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Chris Stoeckert|PERSON: Jie Zheng,,
http://purl.obolibrary.org/obo/OBI_0100086,glucose in solution,glucose molecules,A scattered aggregate of glucose molecules in a liquid,false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,glucose molecules,,,,,,,,,,,,,,,A scattered aggregate of glucose molecules in a liquid,,,,,,,glucose in solution,,Glucose present in blood,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0100086,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,glucose in solution,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Jie Zheng,,
http://purl.obolibrary.org/obo/OBI_0001251,biological activity assay measuring epitope specific interleukin-13 production by T cells,IL-13 release|biological activity,A T cell epitope specific cytokine production assay that detects interleukin-13 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects interleukin-13 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific interleukin-13 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001251,,,,,,,,,,,,,,,,,,,,,,,,IL-13 release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific interleukin-13 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001381,epitope specific interleukin-23 production by T cells,,A process of interleukin-23 production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0032627|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of interleukin-23 production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific interleukin-23 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001381,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific interleukin-23 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/IAO_0000580,looking up a centrally registered identifier,looking up a CRID,A planned process in which a request to a CRID registry is made to return the information associated with a CRID symbol,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,looking up a CRID,,,,,,,,,,,,,,,A planned process in which a request to a CRID registry is made to return the information associated with a CRID symbol,,,,,,,looking up a centrally registered identifier,,Going to the PubMed website and entering a PubMed ID in order to retrieve the Pubmed information associated with that ID. ,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000579,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000577,http://purl.obolibrary.org/obo/IAO_0000030,,,IAO:0000580,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,looking up a centrally registered identifier,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters|PERSON: Melanie Courtot|PERSON: Bill Hogan|PERSON: Alan Ruttenberg,,
http://purl.obolibrary.org/obo/HP_0000855,Insulin resistance,,"Increased resistance towards insulin, that is, diminished effectiveness of insulin in reducing blood glucose levels.",false,,,http://purl.obolibrary.org/obo/BFO_0000016,,,,,,,,,,,,,,,,,,,"Increased resistance towards insulin, that is, diminished effectiveness of insulin in reducing blood glucose levels.",,,,,,,Insulin resistance,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,HP:0000855,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/hp.owl,,,,,,,,,,,,,,,,,,,Insulin resistance,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000570,spin column,,A spin column is a chromatography column which is suitable for putting it into a centrifuge. A spin column enforces separation through increased G-forces while spinning the column in a centrifuge. It is often used in DNA gel extraction kits.,false,,,http://purl.obolibrary.org/obo/OBI_0000038,,,,,,,,,,,,,,,,,,,A spin column is a chromatography column which is suitable for putting it into a centrifuge. A spin column enforces separation through increased G-forces while spinning the column in a centrifuge. It is often used in DNA gel extraction kits.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01232,,,,,,spin column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000570,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,spin column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000852,record of missing knowledge,,a information content entity created to indicate that information about something is not available to the person recording it.,false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,,,,,,,,,,,,,,,,a information content entity created to indicate that information about something is not available to the person recording it.,"",,,,,"This class should probably end up in IAO. It could be further breaken down to indicate different kinds of lack of knowledge, e.g. inability to determine something vs. no attempt made to determine something vs. no informatino available if it was even attempted to determine something. The design pattern should be generalizable. 'unknown sex' is the first example, and needed immediately.",record of missing knowledge,,A statement in a journal article indicating that the age of a patient at the onset of disease is not known. A statement indicating that the weight of a mouse was not measured.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000852,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,record of missing knowledge,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001714,B cell epitope specific immunoglobulin-mediated neutralization,,immunoglobulin-mediated neutralization resulting from antibody binding to epitope,false,,,http://purl.obolibrary.org/obo/GO_0097282,,,,,,,,,,,,,,,,,Date: 2012-05-03; Spreadsheet: BcellAssays.xls; Worksheet: Especific template; Mapping: ebcell_specific_mappings.owl,,immunoglobulin-mediated neutralization resulting from antibody binding to epitope,IEDB (QTT),,,,,,B cell epitope specific immunoglobulin-mediated neutralization,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001714,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,B cell epitope specific immunoglobulin-mediated neutralization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/IAO_0000414,mass measurement datum,,A scalar measurement datum that is the result of measurement of mass quality,false,,,http://purl.obolibrary.org/obo/IAO_0000032,,,,,,,,,,,,,,,,,,,A scalar measurement datum that is the result of measurement of mass quality,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,mass measurement datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000414,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,mass measurement datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0000708,laboratory animal care,,a process that realizes an animal care protocol that specifies how animals are kept and maintained,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,,,a process that realizes an animal care protocol that specifies how animals are kept and maintained,,,,,,,laboratory animal care,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000708,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,laboratory animal care,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000889,survival curve,,A survival curve is a report graph which is a graphical representation of data where the percentage of survival is plotted as a function of time.,false,,,http://purl.obolibrary.org/obo/IAO_0000573,,,,,,,,,,,,,,,,,,,A survival curve is a report graph which is a graphical representation of data where the percentage of survival is plotted as a function of time.,WEB: http://www.graphpad.com/www/book/survive.htm,,,,,,survival curve,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000889,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000789,,,,,,,,,,,,,,,,survival curve,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:James Malone|PERSON:Chris Stoeckert|PERSON:Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0001746,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-1 alpha production by T cells,IL-1a release|RNA/DNA detection,An assay of epitope specific interleukin-1 alpha production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001388,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-1 alpha production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-1 alpha production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001746,,,,,,,,,,,,,,,,,,,,,,,,IL-1a release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-1 alpha production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_1110028,293-T cell line,,"A cell line derived from human embryonic kidney cells. This cell line contains the SV40 Large T-antigen, allowing episomal replication of transfected plasmids containing the SV40 origin of replication.",false,,,http://purl.obolibrary.org/obo/CLO_0009828,,,,,,,,,,,,,,,,,,,"A cell line derived from human embryonic kidney cells. This cell line contains the SV40 Large T-antigen, allowing episomal replication of transfected plasmids containing the SV40 origin of replication.",IEDB|http://www.biotech.ist.unige.it/cldb/cl5008.html,,,,,,293-T cell line,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110028,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,293-T cell line,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001280,biological activity assay measuring epitope specific interleukin-16 production by T cells,IL-16 release|biological activity,A T cell epitope specific cytokine production assay that detects interleukin-16 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects interleukin-16 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific interleukin-16 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001280,,,,,,,,,,,,,,,,,,,,,,,,IL-16 release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific interleukin-16 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/EGO_0000000003,human chromosome I location,,a genomic location in human chromosome I,false,,,http://purl.obolibrary.org/obo/EGO_0000000002,,,,,,,,,,,,,,,,,,,a genomic location in human chromosome I,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,EGO:0000000003,,,,,,,,,,,,,,,,Oliver He,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,human chromosome I location,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/EGO_0000000009,human epigenome,,"a eukaryotic epigenome that exists in human.|The human genome is the complete assembly of DNA (deoxyribonucleic acid)-about 3 billion base pairs - that makes each individual unique. DNA holds the instructions for building the proteins that carry out a variety of functions in a cell. Web: https://www.genome.gov/27532724|The epigenome marks the genome in two main ways, both of which play a role in turning genes on or off. The first type of mark, called DNA methylation, directly affects the DNA in a genome. In this process, proteins attach chemical tags called methyl groups to the bases of the DNA molecule in specific places. The methyl groups turn genes on or off by affecting interactions between the DNA and other proteins. In this way, cells can remember which genes are on or off. The second kind of mark, called histone modification, affects DNA indirectly. DNA in cells is wrapped around histone proteins, which form spool-like structures that enable DNA's very long molecules to be wound up neatly into chromosomes inside the cell nucleus. Proteins can attach a variety of chemical tags to histones.  Other proteins in cells can detect these tags and determine whether that region of DNA should be used or ignored in that cell. Web: https://www.genome.gov/27532724",false,,,http://purl.obolibrary.org/obo/EGO_0000000005,,,,,,,,,,,,,,,,,,,a eukaryotic epigenome that exists in human.,WEB: https://en.wikipedia.org/wiki/Epigenome,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/NCBITaxon_9606,EGO:0000000009,http://purl.obolibrary.org/obo/NCBITaxon_9606,,,,,,,,,,,,,,,"Oliver He, Steve Qin, and Steve Pittard",,"The human genome is the complete assembly of DNA (deoxyribonucleic acid)-about 3 billion base pairs - that makes each individual unique. DNA holds the instructions for building the proteins that carry out a variety of functions in a cell. Web: https://www.genome.gov/27532724|The epigenome marks the genome in two main ways, both of which play a role in turning genes on or off. The first type of mark, called DNA methylation, directly affects the DNA in a genome. In this process, proteins attach chemical tags called methyl groups to the bases of the DNA molecule in specific places. The methyl groups turn genes on or off by affecting interactions between the DNA and other proteins. In this way, cells can remember which genes are on or off. The second kind of mark, called histone modification, affects DNA indirectly. DNA in cells is wrapped around histone proteins, which form spool-like structures that enable DNA's very long molecules to be wound up neatly into chromosomes inside the cell nucleus. Proteins can attach a variety of chemical tags to histones.  Other proteins in cells can detect these tags and determine whether that region of DNA should be used or ignored in that cell. Web: https://www.genome.gov/27532724",,,,,,,,,,,,,,,,,,,,,,,,,,,,human epigenome,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/EGO_0000000002,human genomic location,,a genomic location in human,false,,,http://purl.obolibrary.org/obo/EGO_0000000011,,,,,,,,,,,,,,,,,,,a genomic location in human,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,EGO:0000000002,,,,,,,,,,,,,,,,Oliver He,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,human genomic location,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/EGO_0000000007,MAX binding,,,false,,,http://purl.obolibrary.org/obo/GO_0008134,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,EGO:0000000007,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,MAX binding,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/EGO_0000000006,mouse genomic location,,a genomic location in mouse,false,,,http://purl.obolibrary.org/obo/EGO_0000000011,,,,,,,,,,,,,,,,,,,a genomic location in mouse,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,EGO:0000000006,,,,,,,,,,,,,,,,Oliver He,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,mouse genomic location,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/EGO_0000000004,Pos 3 of human Chr I,,the position 3 in a genomic location in human chromosome I,false,,,http://purl.obolibrary.org/obo/EGO_0000000003,,,,,,,,,,,,,,,,,,,the position 3 in a genomic location in human chromosome I,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,EGO:0000000004,,,,,,,,,,,,,,,,Oliver He,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Pos 3 of human Chr I,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/EGO_0000000001,epigenome,,"a material entity that is made up of chemical compounds and proteins that can attach to DNA and direct such actions as turning genes on or off, controlling the production of proteins in particular cells.|When epigenomic compounds attach to DNA and modify its function, they are said to have ""marked"" the genome. These marks do not change the sequence of the DNA. Rather, they change the way cells use the DNA's instructions. The marks are sometimes passed on from cell to cell as cells divide. They also can be passed down from one generation to the next.",false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,"a material entity that is made up of chemical compounds and proteins that can attach to DNA and direct such actions as turning genes on or off, controlling the production of proteins in particular cells.",WEB: https://en.wikipedia.org/wiki/Epigenome,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,EGO:0000000001,,,,,,,,,,,,,,,,"Oliver He, Steve Qin, and Steve Pittard",,"When epigenomic compounds attach to DNA and modify its function, they are said to have ""marked"" the genome. These marks do not change the sequence of the DNA. Rather, they change the way cells use the DNA's instructions. The marks are sometimes passed on from cell to cell as cells divide. They also can be passed down from one generation to the next.",,,,,,,,,,,,,,,,,,,,,,,,,,,,epigenome,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/EGO_0000000005,eukaryotic epigenome,,an epigenome that exists in a eukaryotic organism,false,,,http://purl.obolibrary.org/obo/EGO_0000000001,,,,,,,,,,,,,,,,,,,an epigenome that exists in a eukaryotic organism,WEB: https://www.genome.gov/27532724,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,EGO:0000000005,,,,,,,,,,,,,,,,"Oliver He, Steve Qin, and Steve Pittard",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,eukaryotic epigenome,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0500012,graeco latin square design,,Greco-Latin square design is a study design which relates to Latin square design,false,,,http://purl.obolibrary.org/obo/OBI_0500007,,,,,,,,,,,,,,,,,only 2 articles in pubmed ->probably irrelevant,,Greco-Latin square design is a study design which relates to Latin square design,Adapted from: http://www.itl.nist.gov/div898/handbook/pri/section3/pri3321.htm and,,,,,,graeco latin square design,,"PMID: 6846242-Beaton et al (Am J Clin Nutr 1979;32:2546-59) reported on the partitioning of variance in 1-day dietary data for the intake of energy, protein, total carbohydrate, total fat, classes of fatty acids, cholesterol, and alcohol. Using the same food intake data and the expanded National Heart, Lung and Blood Institute food composition data base, these analyses of sources of variance have been expanded to include classes of carbohydrate, vitamin A, vitamin C, thiamin, riboflavin, niacin, calcium, iron, total ash, caffeine, and crude fiber. The analyses relate to observed intakes (replicated six times) of 30 adult males and 30 adult females obtained under a paired Graeco-Latin square design with sequence of interview, interviewer, and day of the week as determinants. Neither sequence nor interviewer made consistent contribution to variance. In females, day of the week had a significant effect for several nutrients. The major partitioning of variance was between interindividual variation (between subjects) and intraindividual variation (within subjects) which included both true day-to-day variation in intake and methodological variation. For all except caffeine, the intraindividual variability of 1-day data was larger than the interindividual variability. For vitamin A, almost all of the variance was associated with day-to-day variability. One day data provide a very inadequate estimate of usual intake of individuals. In the design of nutrition studies it is critical that the intended use of dietary data be a major consideration in deciding on methodology. There is no ideal dietary method. There may be preferred methods for particular purposes.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500012,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,graeco latin square design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0200097,non-negative matrix factorization,,Non negative matrix factorization is a data transformation in which factorises a matrix and which forces that all elements must be equal to or greater than zero.,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,Non negative matrix factorization is a data transformation in which factorises a matrix and which forces that all elements must be equal to or greater than zero.,http://en.wikipedia.org/wiki/Non-negative_matrix_factorization,,,,,,non-negative matrix factorization,,Non-negative matrix factorization is used in text mining where document-term matrix is constructed with the weights of various terms (typically weighted word frequency information) from a set of documents. This matrix is factored into a term-feature and a feature-document matrix.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200097,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,non-negative matrix factorization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000896,secondary structure of RNA molecule,,"",false,,,http://purl.obolibrary.org/obo/OBI_0000885,,,,,,,,,,,,,,,,,,,"",,,,,,2010-01-31: Philippe Rocca-Serra: This is a placeholder to allow work on 'nucleic acid mapping assay' in collaboration with RNAOntology group. Need to liaise with SO,secondary structure of RNA molecule,,PMID: 15630685: Single molecule studies of RNA secondary structure: AFM of TYMV viral RNA.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000896,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,secondary structure of RNA molecule,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000567,Bruker UltraShield NMR magnet,,An NMR magnet manufactured by Bruker that ensures field homogeneity without amplified effects from vibrations or thermal changes. This magnet technology uses active shielding and optimizes coil design.,false,,,http://purl.obolibrary.org/obo/OBI_0000597,,,,,,,,,,,,,,,,,NMR instrument,,An NMR magnet manufactured by Bruker that ensures field homogeneity without amplified effects from vibrations or thermal changes. This magnet technology uses active shielding and optimizes coil design.,WEB:<http://www.bruker-biospin.com/nmr_magnets_us.html?&print=http%3A%2Fitsupportunit.com%2Fawstats%2Ficon%2Fnisum%2Fivuj%2F>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400187,,,,,,Bruker UltraShield NMR magnet,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000567,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker UltraShield NMR magnet,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/CHEBI_31624,fluorescein,,"A xanthene dye that is a highly fluorescent dye, detectable even when present in minute quantities. Used forensically to detect traces of blood, in analytical chemistry as an indicator in silver nitrate titrations and in microscopy.",false,,,http://purl.obolibrary.org/obo/REO_0000280,,,,,,,,,,,,,,,,,,,"A xanthene dye that is a highly fluorescent dye, detectable even when present in minute quantities. Used forensically to detect traces of blood, in analytical chemistry as an indicator in silver nitrate titrations and in microscopy.",,,,,,,fluorescein,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/REO_0000171,,,,,,,,,,,,CHEBI:31624,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,fluorescein,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001964,decision-theoretic analysis objective,decision analysis objective,"An objective specification which what includes a description of two or more alternative actions to take in a particular situation and a metric that enables comparisons of the two actions. The objective specified is achieved in a planned process which includes a data transformation, the output of which is an identification of the 'best' choice according to the metric.",false,,,http://purl.obolibrary.org/obo/IAO_0000005,,,,decision analysis objective,,,,,,,,,,,,,,,"An objective specification which what includes a description of two or more alternative actions to take in a particular situation and a metric that enables comparisons of the two actions. The objective specified is achieved in a planned process which includes a data transformation, the output of which is an identification of the 'best' choice according to the metric.",PERSON: Bill Hogan,,,,,The best action to take is typically defined as the one that maximizes expected utility.,decision-theoretic analysis objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001964,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,decision-theoretic analysis objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bill Hogan,,
http://purl.obolibrary.org/obo/OBI_0001089,microhardness tester,,A hardness testing device that is used in light-optical microscopes.,false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,A hardness testing device that is used in light-optical microscopes.,United States Patent 4611487,,,,,,microhardness tester,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001089,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,microhardness tester,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0000234,trial statistician role,trial statistician,a worker role that analyzes data obtained during a trial or study; this role occurs after the trial or study is completed or terminated.,false,,,http://purl.obolibrary.org/obo/OBI_0000116,,,,trial statistician,,,,,,,,,,,,,CDISC definition:  trial statistician. A statistician who has a combination of education/training and experience sufficient to implement the principles in the ICH E9 guidance and who is responsible for the statistical aspects of the trial. [ICH E9],,a worker role that analyzes data obtained during a trial or study; this role occurs after the trial or study is completed or terminated.,,,,,,,trial statistician role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000234,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,trial statistician role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0001011,ENU structure mapping assay,single nucleotide resolution mapping assay using ENU probe,a single-nucleotide-resolution nucleic acid structure mapping assay which uses ENU as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,false,,,http://purl.obolibrary.org/obo/OBI_0001017,,http://purl.obolibrary.org/obo/OBI_0000441,,single nucleotide resolution mapping assay using ENU probe,,,,,,,,,,,,,,,a single-nucleotide-resolution nucleic acid structure mapping assay which uses ENU as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,RNA ontology,,,,,,ENU structure mapping assay,,PMID:7002606 and PMID:2446263,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001011,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENU structure mapping assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001357,detection of specific nucleic acids with complementary probes assay measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells,GM-CSF release|RNA/DNA detection,An assay of epitope specific granulocyte macrophage colony stimulating factor production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001233,,,,,,,,,,,,,,,,,,,An assay of epitope specific granulocyte macrophage colony stimulating factor production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001357,,,,,,,,,,,,,,,,,,,,,,,,GM-CSF release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_1110055,obsolete_disease,,placeholder to be imported from disease ontology,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,placeholder to be imported from disease ontology,IEDB,,,,,,obsolete_disease,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000121,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000228,,,,,,,,,,,,,,,,,,OBI:1110055,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_disease,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,http://purl.obolibrary.org/obo/OGMS_0000031,
http://purl.obolibrary.org/obo/OBI_0001170,reverse transcription polymerase chain reaction assay,,"an assay that evaluates the concentration of RNA in a sample in which an RNA strand is first reverse transcribed into its DNA complement (complementary DNA, or cDNA) using the enzyme reverse transcriptase, and the resulting cDNA is amplified using traditional or real-time PCR. ",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,"an assay that evaluates the concentration of RNA in a sample in which an RNA strand is first reverse transcribed into its DNA complement (complementary DNA, or cDNA) using the enzyme reverse transcriptase, and the resulting cDNA is amplified using traditional or real-time PCR. ",GROUP: Penn Group,,,,,,reverse transcription polymerase chain reaction assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000552,,,,,,,,,,,,,,,,OBI:0001170,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,reverse transcription polymerase chain reaction assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://www.geneontology.org/formats/oboInOwl#Definition,Definition,,,false,,,http://purl.obolibrary.org/obo/IAO_0000102,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,oboInOwl:Definition,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0400027,CytoBuoy flow cytometer analyzer,,"A flow cytometer analyser which is manufactured by Cyto Buoy Inc. They are the buoy mounted version of the CytoSense, equipped with wireless transmission of control and data files. They are a single laser, multi parameter instrument. Various types of micro-laser are offered; available measuring parameters are forward light scatter, side scatter, and fluorescence (max. 9 colour bands). The current series have 5 parameters.",false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,,,,,,,,,,,,,,,,"A flow cytometer analyser which is manufactured by Cyto Buoy Inc. They are the buoy mounted version of the CytoSense, equipped with wireless transmission of control and data files. They are a single laser, multi parameter instrument. Various types of micro-laser are offered; available measuring parameters are forward light scatter, side scatter, and fluorescence (max. 9 colour bands). The current series have 5 parameters.",http://www.cytobuoy.com/,,,,,,CytoBuoy flow cytometer analyzer,,CytoBuoy can be used to conduct extended and/or high frequency time series of phytoplankton distribution and abundance on fixed locations,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400027,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CytoBuoy flow cytometer analyzer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"John Quinn, Melanie Courtot",,
http://purl.obolibrary.org/obo/OBI_0002025,Human Exon 1.0 ST tilling array,Human Exon 1.0|Human Exon 1.0 ST Array|Affymetrix Human Exon 1.0 St Array,"A tiling microarray which is manufactured by the Affymetrix corporation. Built to analyze 3' DNA sequence copy number by comparative genomic hybridization for human DNA against 28,000 genes. It  can be used for gene expression and alternative splicing assay",false,,,http://purl.obolibrary.org/obo/OBI_0001307,,,,Human Exon 1.0|Human Exon 1.0 ST Array|Affymetrix Human Exon 1.0 St Array,,,,,,,,,,,,,,,"A tiling microarray which is manufactured by the Affymetrix corporation. Built to analyze 3' DNA sequence copy number by comparative genomic hybridization for human DNA against 28,000 genes. It  can be used for gene expression and alternative splicing assay",http://www.affymetrix.com/catalog/131453/AFFY/Human+Gene+ST+Arrays#1_1,,,,,,Human Exon 1.0 ST tilling array,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002025,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Human Exon 1.0 ST tilling array,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001953,freezing,,A planned process in which a material entity has it's temperature lowered to below the freezing point in order to bring it to a state in which it can be maintained at this lower temperature in order to preserve some of its qualities.,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,,,A planned process in which a material entity has it's temperature lowered to below the freezing point in order to bring it to a state in which it can be maintained at this lower temperature in order to preserve some of its qualities.,Mathias Brochhausen,,,,,,freezing,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001953,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,freezing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Mathias Brochhausen, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000970,scalar score from composite inputs,questionaire score,"A measurement datum which is the result of combining multiple datum. For example, a mean or summary score. ",false,,,http://purl.obolibrary.org/obo/IAO_0000032,,,,questionaire score,,,,,,,,,,,,,"JZ: can we defined it logically as the output of some data transformation, like aggragate data transformation?",,"A measurement datum which is the result of combining multiple datum. For example, a mean or summary score. ",Person: Jessica Turner,,,,,"JT:  We included this because we wanted to talk about an output from a questionnaire that summarized the answers to the questionnaire, but which was not actually the answer to any single question. ",scalar score from composite inputs,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000970,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0200000,,,scalar score from composite inputs,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jessica Turner,,
http://purl.obolibrary.org/obo/OBI_1110017,living with infected household contact,,a process in which a a human being lives in the same household as another human being that is known to be infected with an infectious agent,false,,,http://purl.obolibrary.org/obo/OBI_1110111,,,,,,,,,,,,,,,,,,,a process in which a a human being lives in the same household as another human being that is known to be infected with an infectious agent,IEDB,,,,,,living with infected household contact,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110017,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,living with infected household contact,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001742,quenching assay measuring the on rate [kon] of a B cell epitope:antibody complex,on rate|quenching|M^-1s^-1,A B cell epitope on rate measurement (kon) determination assay that uses an antibody binding detection by fluorescence quenching assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001718|http://purl.obolibrary.org/obo/OBI_0001499,,,,,,,,,,,,,,,,,,,A B cell epitope on rate measurement (kon) determination assay that uses an antibody binding detection by fluorescence quenching assay.,IEDB,,,,,,quenching assay measuring the on rate [kon] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001742,,,,,,,,,,,,,,,,,,,,,,,,on rate|quenching|M^-1s^-1,,,,,,,,,,,,,,,,,,,,,,quenching assay measuring the on rate [kon] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000916,flow cytometry assay,,"A cytometry assay in which an input cell population is put in solution, is passed by a laser, and optical sensors are used to detect scattering of the laser light and/or fluorescence of specific markers to count and characterize the particles in solution.",false,,,http://purl.obolibrary.org/obo/OBI_0001977,,,,,,,,,,,,,,,,,,,"A cytometry assay in which an input cell population is put in solution, is passed by a laser, and optical sensors are used to detect scattering of the laser light and/or fluorescence of specific markers to count and characterize the particles in solution.",IEDB,,,,,,flow cytometry assay,,Using a flow cytometer to quantitate the percent of CD3 positive cells in a population by labeling them with a FITC tagged anti-CD3 antibody.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000916,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,flow cytometry assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_1110155,ELISA measuring epitope specific tumor necrosis factor production by T cells,TNFa release|ELISA,A T cell epitope specific tumor necrosis factor production assay that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001416|http://purl.obolibrary.org/obo/OBI_0001246,,,,,,,,,,,,,,,,,,,A T cell epitope specific tumor necrosis factor production assay that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific tumor necrosis factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110155,,,,,,,,,,,,,,,,,,,,,,,,TNFa release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific tumor necrosis factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001851,transcription start site identification objective,,A transcription profiling identification objective that aims to characterize the transcription start sites of genes.,false,,,http://purl.obolibrary.org/obo/OBI_0001331,,,,,,,,,,,,,,,,,,,A transcription profiling identification objective that aims to characterize the transcription start sites of genes.,Penn Group,,,,,,transcription start site identification objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001851,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,transcription start site identification objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001155,3D structural organization datum,,A measurement datum that describes the structural orientation of a material entity in 3D space. ,false,,,http://purl.obolibrary.org/obo/IAO_0000109,,,,,,,,,,,,,,,,,,,A measurement datum that describes the structural orientation of a material entity in 3D space. ,,,,,,,3D structural organization datum,,"The atom coordinates found in a PDB (Protein Data Bank) file, generated by X Ray crystallography or NMR. ",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001155,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,3D structural organization datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Jason Greenbaum, Randi Vita, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001532,cytometric bead array assay measuring epitope specific interleukin-9 production by T cells,IL-9 release|cytometric bead array,An assay of epitope specific interleukin-9 production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001253,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-9 production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific interleukin-9 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001532,,,,,,,,,,,,,,,,,,,,,,,,IL-9 release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific interleukin-9 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001642,biological activity assay measuring epitope specific antibody-dependent cellular cytotoxicity,antibody-dependent cellular cytotoxicity|biological activity,A B cell epitope specific activation of additional immune response in vitro assay that detects antibody-dependent cellular cytotoxicity.,false,,,http://purl.obolibrary.org/obo/OBI_0001704,,,,,,,,,,,,,,,,,,,A B cell epitope specific activation of additional immune response in vitro assay that detects antibody-dependent cellular cytotoxicity.,IEDB,,,,,,biological activity assay measuring epitope specific antibody-dependent cellular cytotoxicity,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001642,,,,,,,,,,,,,,,,,,,,,,,,antibody-dependent cellular cytotoxicity|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific antibody-dependent cellular cytotoxicity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_1110193,epitope specific IL-17 release by T cells,,A biological process where T cells produce IL-17 resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0032620|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,,,A biological process where T cells produce IL-17 resulting from the recognition of a T cell epitope.,IEDB,,,,,,epitope specific IL-17 release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110193,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific IL-17 release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000686,material combination objective,,is an objective to obtain an output material that contains several input materials.,false,,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,,,is an objective to obtain an output material that contains several input materials.,bp,,,,,,material combination objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000686,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,material combination objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PPPB branch,,
http://purl.obolibrary.org/obo/OBI_0000734,DNA sequencing by synthesis,,is a DNA sequencing which relies on DNA polymerase activity to perform chain extension during the sequencing reaction step.,false,,,http://purl.obolibrary.org/obo/OBI_0000626,,,,,,,,,,,,,,,,,,,is a DNA sequencing which relies on DNA polymerase activity to perform chain extension during the sequencing reaction step.,,,,,,,DNA sequencing by synthesis,,"PMID: 18263613. A new class of cleavable fluorescent nucleotides: synthesis and optimization as reversible terminators for DNA sequencing by synthesis. Turcatti G, Romieu A, Fedurco M, Tairi AP. Nucleic Acids Res. 2008 Mar;36(4):e25.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/GO_0042575,,,,OBI:0000734,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNA sequencing by synthesis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/IAO_0000402,two dimensional cartesian spatial coordinate datum,,A cartesion spatial coordinate datum that  uses two values to specify a position within a two dimensional spatial region,false,,,http://purl.obolibrary.org/obo/IAO_0000400,,,,,,,,,,,,,,,,,,,A cartesion spatial coordinate datum that  uses two values to specify a position within a two dimensional spatial region,,,,,,,two dimensional cartesian spatial coordinate datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000402,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,two dimensional cartesian spatial coordinate datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_1110173,intracellular cytokine staining assay measuring epitope specific interleukin-2 production by T cells,IL-2 release|ICS,An assay of epitope specific interleukin-2 production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001445,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-2 production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-2 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110173,,,,,,,,,,,,,,,,,,,,,,,,IL-2 release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-2 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001132,capillary electrophoresis instrument,,An electrophoresis system that is used to separate ionic species by their charge and frictional forces and mass.,false,,,http://purl.obolibrary.org/obo/OBI_0001053,,,,,,,,,,,,,,,,,,,An electrophoresis system that is used to separate ionic species by their charge and frictional forces and mass.,http://en.wikipedia.org/wiki/Capillary_electrophoresis,,,,,,capillary electrophoresis instrument,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001132,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,capillary electrophoresis instrument,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001615,investigation description,project description|study description,A textual entity that describes an investigation.,false,,,http://purl.obolibrary.org/obo/IAO_0000300,,,,,,,,,,,,,,,,,,,A textual entity that describes an investigation.,NIAID GSCID-BRC metadata working group,,,,,,investigation description,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001615,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000066,,,,,,,,,,,,,,,study description,investigation description,,,,,,project description,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/BFO_0000009,two-dimensional spatial region,,,false,,,http://purl.obolibrary.org/obo/BFO_0000006,,,,,,,TwoDimensionalSpatialRegion,2d-s-region,,,,,,,,,,,,,,,,,,two-dimensional spatial region,A two-dimensional spatial region is a spatial region that is of two dimensions. (axiom label in BFO2 Reference: [039-001]),an infinitely thin plane in space.|the surface of a sphere-shaped part of space,,,,,,,,(forall (x) (if (TwoDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [039-001] ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000009,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,two-dimensional spatial region,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000500,dual loop autosampler,,A dual loop autosampler is an autosampler that is designed for handling both analytical (10 mL/min flow rate) to preparative scale sample purification (100 mL/min flow rate).,false,,,http://purl.obolibrary.org/obo/OBI_0000494,,,,,,,,,,,,,,,,,,,A dual loop autosampler is an autosampler that is designed for handling both analytical (10 mL/min flow rate) to preparative scale sample purification (100 mL/min flow rate).,WEB:<http://www.chem.agilent.com/scripts/pds.asp?lpage=17149>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01063,,,,,,dual loop autosampler,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000500,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,dual loop autosampler,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_1110034,antigen,,is a material entity that has the antigen role,false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,is a material entity that has the antigen role,IEDB,,,,,,antigen,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110034,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,antigen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001303,intracellular cytokine staining assay measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells,GM-CSF release|ICS,An assay of epitope specific granulocyte macrophage colony stimulating factor production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001233,,,,,,,,,,,,,,,,,,,An assay of epitope specific granulocyte macrophage colony stimulating factor production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001303,,,,,,,,,,,,,,,,,,,,,,,,GM-CSF release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000975,cell-cell binding detection by flow cytometry assay,,A binding assay which uses a flow cytometer to detect pairs of cells that are bound to each other by staining them with different fluorescent labels.,false,,,http://purl.obolibrary.org/obo/OBI_0001499|http://purl.obolibrary.org/obo/OBI_0001977,,,,,,,,,,,,,,,,,,,A binding assay which uses a flow cytometer to detect pairs of cells that are bound to each other by staining them with different fluorescent labels.,IEDB,,,,,,cell-cell binding detection by flow cytometry assay,,"Staining a B cell with PE and staining a T cell with FITC, incubating them together with a peptide, and counting the number of co-stained conjugates.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000975,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cell-cell binding detection by flow cytometry assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001140,spike-in quality control role,,a reference substance role that is borne by a material entity with a known amount which is mixed into the evaluant of assays for quality control or data normalization purposes,false,,,http://purl.obolibrary.org/obo/OBI_0000025,,,,,,,,,,,,,,,,,,,a reference substance role that is borne by a material entity with a known amount which is mixed into the evaluant of assays for quality control or data normalization purposes,MO_937 spike_quality_control,,,,,,spike-in quality control role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,spike-in quality control role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng, Bjoern Peter",,
http://purl.obolibrary.org/obo/OBI_0000020,contract research organization role,contract research organization,"a worker role of carrying out the study according to the protocol document or study plan delivered by the PI, under the control of the study director.  This role cannot make decisions about the study execution",false,,,http://purl.obolibrary.org/obo/OBI_0000116,,,,contract research organization,,,,,,,,,,,,,,,"a worker role of carrying out the study according to the protocol document or study plan delivered by the PI, under the control of the study director.  This role cannot make decisions about the study execution",,,,,,,contract research organization role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000020,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,contract research organization role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0400077,neodymium-YAG laser,,"A Neodymium-YAG (yttrium aluminum garnet) laser is a solid state laser in which the lasing medium is a solid rod of crystalline material pumped by a flash lamp or a diode laser. Typical output wavelengths are 355, 532, and 1064 nm. A neodymium-YAG laser can by used to irradiate cells in a flow cytometer.",false,,,http://purl.obolibrary.org/obo/OBI_0400096,,,,,,,,,,,,,,,,,,,"A Neodymium-YAG (yttrium aluminum garnet) laser is a solid state laser in which the lasing medium is a solid rod of crystalline material pumped by a flash lamp or a diode laser. Typical output wavelengths are 355, 532, and 1064 nm. A neodymium-YAG laser can by used to irradiate cells in a flow cytometer.",John Quinn,,,,,,neodymium-YAG laser,,Neodymium-YAG Laser in DURIP99 System,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400077,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,neodymium-YAG laser,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001940,N50,weighted median item size,"the weighted median item size or N50 is a weighted median of the lengths of items, equal to the length of the longest item i such that the sum of the lengths of items greater than or equal in length to i is greater than or equal to half the length of all of the items. With regard to assemblies the items are typically contigs or scaffolds. It therefore denotes the ability of the software to create contigs and provides information about the resulting sequence assembly",false,,,http://purl.obolibrary.org/obo/IAO_0000032,,,,weighted median item size,,,,,,,,,,,,,,,"the weighted median item size or N50 is a weighted median of the lengths of items, equal to the length of the longest item i such that the sum of the lengths of items greater than or equal in length to i is greater than or equal to half the length of all of the items. With regard to assemblies the items are typically contigs or scaffolds. It therefore denotes the ability of the software to create contigs and provides information about the resulting sequence assembly","adapted from:
""http://genome.cshlp.org/content/21/12/2224.full?sid=74019122-f944-4ccc-bffe-d16fdd0e7d6c""
(from table 7)
and from ""http://www.nature.com/nrg/journal/v14/n3/full/nrg3367.html""",,,,,,N50,,"Gigascience. 2012 Dec 27;1(1):18. doi: 10.1186/2047-217X-1-18.
PMID: 23587118. 

""Here, the contig and scaffold N50 of the YH genome were ~20.9 kbp and ~22 Mbp""",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000003,,,,,,,,,,,,,,,,,,,,,OBI:0001940,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/SO_0001248,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001872,,,N50,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Alejandra Gonzalez-Beltran|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001273,cell culture analyte detection bioassay measuring epitope specific interleukin-5 production by T cells,IL-5 release|bioassay,An assay of epitope specific interleukin-5 production by T cells that uses a cell culture analyte detection bioassay.,false,,,http://purl.obolibrary.org/obo/OBI_0001230,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-5 production by T cells that uses a cell culture analyte detection bioassay.,IEDB,,,,,,cell culture analyte detection bioassay measuring epitope specific interleukin-5 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001273,,,,,,,,,,,,,,,,,,,,,,,,IL-5 release|bioassay,,,,,,,,,,,,,,,,,,,,,,cell culture analyte detection bioassay measuring epitope specific interleukin-5 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_1110003,host exposure to infectious agent,,a process in which an infectious agent comes into physical contact with a host organism.,false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,a process in which an infectious agent comes into physical contact with a host organism.,IEDB,,,,,,host exposure to infectious agent,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110003,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,host exposure to infectious agent,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000978,in container assay,,an assay in which a measurement is made by observing entities located in a container.,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,an assay in which a measurement is made by observing entities located in a container.,,,,,,,in container assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000978,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,in container assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0002019,transcription factor binding site identification by ChIP-Seq assay,TF Binding ChIP-Seq,A ChIP-seq assay to identify binding sites for transcription factors.,false,,,http://purl.obolibrary.org/obo/OBI_0000716|http://purl.obolibrary.org/obo/OBI_0000291,,http://purl.obolibrary.org/obo/OBI_0001398,,TF Binding ChIP-Seq,,,,,,,,,,,,,,,A ChIP-seq assay to identify binding sites for transcription factors.,Penn group,,,,,,transcription factor binding site identification by ChIP-Seq assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002019,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,transcription factor binding site identification by ChIP-Seq assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Beta Cell Biology Consoritum,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001843,detection of specific nucleic acids with complementary probes measuring epitope specific interleukin-15 production by T cells,IL-15 release|RNA/DNA detection,An assay of epitope specific interleukin-15 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001292,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-15 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes measuring epitope specific interleukin-15 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001843,,,,,,,,,,,,,,,,,,,,,,,,IL-15 release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes measuring epitope specific interleukin-15 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001516,cell lysate MHC direct binding assay measuring half maximal effective concentration [EC50] of a MHC:ligand complex using radioactivity detection,half maximal effective concentration (EC50)|lysate MHC/direct/radioactivity|nM,A cell lysate MHC ligand binding half maximal effective concentration (EC50) determination assay that uses radioactivity detection to measure direct ligand binding.,false,,,http://purl.obolibrary.org/obo/OBI_0001991|http://purl.obolibrary.org/obo/OBI_0001491,,,,,,,,,,,,,,,,,,,A cell lysate MHC ligand binding half maximal effective concentration (EC50) determination assay that uses radioactivity detection to measure direct ligand binding.,IEDB,,,,,,cell lysate MHC direct binding assay measuring half maximal effective concentration [EC50] of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001516,,,,,,,,,,,,,,,,,,,,,,,,half maximal effective concentration (EC50)|lysate MHC/direct/radioactivity|nM,,,,,,,,,,,,,,,,,,,,,,cell lysate MHC direct binding assay measuring half maximal effective concentration [EC50] of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/PATO_0002202,left handedness,,Handedness where the organism preferentially uses the left hand or foot for tasks requiring the use of a single hand or foot or a dominant hand or foot.,false,,,http://purl.obolibrary.org/obo/PATO_0002201,,,,,,,,,,,,,,,,,,,Handedness where the organism preferentially uses the left hand or foot for tasks requiring the use of a single hand or foot or a dominant hand or foot.,,,,,,,left handedness,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0002202,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,left handedness,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0002204,ambidextrous handedness,,Handedness where the organism exhibits no overall dominance in the use of right or left hand or foot in the performance of tasks that require one hand or foot or a dominant hand or foot.,false,,,http://purl.obolibrary.org/obo/PATO_0002201,,,,,,,,,,,,,,,,,,,Handedness where the organism exhibits no overall dominance in the use of right or left hand or foot in the performance of tasks that require one hand or foot or a dominant hand or foot.,,,,,,,ambidextrous handedness,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0002204,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,ambidextrous handedness,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0002203,right handedness,,Handedness where the organism preferentially uses the right hand or foot for tasks requiring the use of a single hand or foot or a dominant hand or foot.,false,,,http://purl.obolibrary.org/obo/PATO_0002201,,,,,,,,,,,,,,,,,,,Handedness where the organism preferentially uses the right hand or foot for tasks requiring the use of a single hand or foot or a dominant hand or foot.,,,,,,,right handedness,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0002203,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,right handedness,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0002201,handedness,,A behavioral quality inhering ina bearer by virtue of the bearer's unequal distribution of fine motor skill between its left and right hands or feet.,false,,,http://purl.obolibrary.org/obo/PATO_0000186,,,,,,,,,,,,,,,,,,,A behavioral quality inhering ina bearer by virtue of the bearer's unequal distribution of fine motor skill between its left and right hands or feet.,,,,,,,handedness,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0002201,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,handedness,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0400032,differential pressure gauge,,"Part of the fluidics subsystem. The differential pressure gauge monitors the difference between sample and sheath fluid pressures in systems where pressure is used to force the sample fluid to flow in the center of the sheath fluid. A differential pressure gauge can be used by the operator to make sure that the sample fluid is at a greater pressure than the sheath fluid, which maintains a core of sample fluid.",false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,"Part of the fluidics subsystem. The differential pressure gauge monitors the difference between sample and sheath fluid pressures in systems where pressure is used to force the sample fluid to flow in the center of the sheath fluid. A differential pressure gauge can be used by the operator to make sure that the sample fluid is at a greater pressure than the sheath fluid, which maintains a core of sample fluid.","Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253",,,,,,differential pressure gauge,,LSR2 differential pressure gauge,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400032,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,differential pressure gauge,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0001032,light emission device,,a device which has a function to emit light.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,a device which has a function to emit light.,OBI,,,,,,light emission device,,"A light source is an optical subsystem that provides light for use in a distant area using a delivery system (e.g., fiber optics)",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001032,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,light emission device,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Helen Parkinson,,
http://purl.obolibrary.org/obo/GO_0005216,ion channel activity,,Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.,false,,,http://purl.obolibrary.org/obo/GO_0009987,,,,,,,,,,,,,,,,,,,Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.,,,,,,,ion channel activity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0005216,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,ion channel activity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000275,analyte role,,A role borne by a molecular entity or an atom and realized in an analyte assay which achieves the objective to measure the magnitude/concentration/amount of the analyte in the entity bearing evaluant role,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,"Feb 10, 2009.  changes after discussion at OBI Consortium Workshop Feb 2-6, 2009.  accepted as core term.",,A role borne by a molecular entity or an atom and realized in an analyte assay which achieves the objective to measure the magnitude/concentration/amount of the analyte in the entity bearing evaluant role,OBI,,,,,"qualities such as weight, color are not assayed but measured, so they do not fall into this category.|interestingly, an analyte is still an analyte even if it is not detected.  for this reason it does not bear a specified input role|pH (technically the inverse log of [H+]) may be considered a quality; this remains to be tested.",analyte role,,Glucose in blood (measured in an assay to determine the concentration of glucose).,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000275,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,analyte role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP: Role Branch,,
http://purl.obolibrary.org/obo/OBI_0200167,data normalization objective,,"A normalization objective is a data transformation objective where the aim is to remove
systematic sources of variation to put the data on equal footing in order
to create a common base for comparisons.",false,,,http://purl.obolibrary.org/obo/OBI_0200166,,,,,,,,,,,,,,,,,,,"A normalization objective is a data transformation objective where the aim is to remove
systematic sources of variation to put the data on equal footing in order
to create a common base for comparisons.",PERSON: James Malone|PERSON: Helen Parkinson|PERSON: Elisabetta Manduchi,,,,,,data normalization objective,,"Quantile transformation which has normalization objective can be used for expression microarray assay normalization and it is referred to as ""quantile normalization"", according to the procedure described e.g. in PMID 12538238.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200167,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,data normalization objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Helen Parkinson|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OGMS_0000031,disease,,A disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism.,false,,,http://purl.obolibrary.org/obo/BFO_0000016,,,,,,,,,,,,,,,,,,,A disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism.,,,,,,,disease,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OGMS:0000031,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ogms.owl,,,,,,,,,,,,,,,,,,,disease,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000920,cytometric bead array assay,Luminex assay,An analyte assay in which a series of beads coated with antibodies specific for different analytes and marked with discrete fluorescent labels are used to simultaneously capture and quantitate soluble analytes.,false,,,http://purl.obolibrary.org/obo/OBI_0000443,,,,Luminex assay,,,,,,,,,,,,,,,An analyte assay in which a series of beads coated with antibodies specific for different analytes and marked with discrete fluorescent labels are used to simultaneously capture and quantitate soluble analytes.,IEDB,,,,,,cytometric bead array assay,,Using a Luminex machine to detect IFN-gamma and IL-10 in the supernatant of a cell culture.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000920,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001517,cell bound MHC competitive binding assay measuring half maximal inhibitory concentration [IC50] of a MHC:ligand complex using radioactivity detection,half maximal inhibitory concentration (IC50)|cellular MHC/competitive/radioactivity|nM,A cell bound MHC ligand binding half maximal inhibitory concentration (IC50) determination assay that uses radioactivity detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation.,false,,,http://purl.obolibrary.org/obo/OBI_0001491|http://purl.obolibrary.org/obo/OBI_0001992,,,,,,,,,,,,,,,,,,,A cell bound MHC ligand binding half maximal inhibitory concentration (IC50) determination assay that uses radioactivity detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation.,IEDB,,,,,,cell bound MHC competitive binding assay measuring half maximal inhibitory concentration [IC50] of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001517,,,,,,,,,,,,,,,,,,,,,,,,half maximal inhibitory concentration (IC50)|cellular MHC/competitive/radioactivity|nM,,,,,,,,,,,,,,,,,,,,,,cell bound MHC competitive binding assay measuring half maximal inhibitory concentration [IC50] of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001777,biological activity assay measuring epitope specific chemokine (C-C motif) ligand 22 production by T cells,CCL22/MDC release|biological activity,A T cell epitope specific cytokine production assay that detects chemokine (C-C motif) ligand 22 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects chemokine (C-C motif) ligand 22 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific chemokine (C-C motif) ligand 22 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001777,,,,,,,,,,,,,,,,,,,,,,,,CCL22/MDC release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific chemokine (C-C motif) ligand 22 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001151,genetically modified material,,"a material entity, organism or cell,  that is the output of a genetic transformation process. ",false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,,,,,,,,,,,,,,"term is proposed by BP on Oct 25, 2010 dev call",,"a material entity, organism or cell,  that is the output of a genetic transformation process. ",GROUP: OBI,,,,,,genetically modified material,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001151,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,genetically modified material,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Jie Zheng,,
http://purl.obolibrary.org/obo/OBI_0000017,regulatory role,,"a role which inheres in material entities and is realized in the processes of making, enforcing or being defined by legislation or orders issued by a governmental body.",false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,govt agents responsible for creating regulations; proxies for enforcing regulations.  CDISC definition:  regulatory authorities. Bodies having the power to regulate. NOTE: In the ICH GCP guideline the term includes the authorities that review submitted clinical data and those that conduct inspections. These bodies are sometimes referred to as competent,,"a role which inheres in material entities and is realized in the processes of making, enforcing or being defined by legislation or orders issued by a governmental body.","OBI, CDISC",,,,,,regulatory role,,"Regulatory agency, Ethics committee, Approval letter; example:  Browse these EPA Regulatory Role subtopics  http://www.epa.gov/ebtpages/enviregulatoryrole.html  Feb 29, 2008",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000017,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,regulatory role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP:  Role branch,,
http://purl.obolibrary.org/obo/OBI_0001343,detection of specific nucleic acids with complementary probes assay measuring epitope specific monocyte chemotactic protein-1 production by T cells,CCL2/MCP-1 release|RNA/DNA detection,An assay of epitope specific monocyte chemotactic protein-1 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001465,,,,,,,,,,,,,,,,,,,An assay of epitope specific monocyte chemotactic protein-1 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific monocyte chemotactic protein-1 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001343,,,,,,,,,,,,,,,,,,,,,,,,CCL2/MCP-1 release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific monocyte chemotactic protein-1 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0100010,Epstein Barr virus transformed B cell,,A material entity which results from viral transformation process using EBV as transformation agent when applied to B-cell entity,false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,,,,,,,,,,,,,,,,A material entity which results from viral transformation process using EBV as transformation agent when applied to B-cell entity,GROUP: OBI Biomaterial Branch,,,,,,Epstein Barr virus transformed B cell,,PMID: 8777380. Expression of thyroid peroxidase in EBV-transformed B cell lines using adenovirus.Thyroid. 1996 Feb;6(1):23-8.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0100010,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Epstein Barr virus transformed B cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Susanna Sansone,,
http://purl.obolibrary.org/obo/OBI_0001984,treatment intervention experiment,,An in vivo intervention experiment in which the ability of the intervention to reduce or cure the effects of a disease are tested.,false,,,http://purl.obolibrary.org/obo/OBI_0001980,,,,,,,,,,,,,,,,,,,An in vivo intervention experiment in which the ability of the intervention to reduce or cure the effects of a disease are tested.,IEDB,,,,,should have treatment as intervention,treatment intervention experiment,,Testing if administering oral histamine-blockers will reduce the number of emergency room visits in severely asthmatic individuals.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001984,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,treatment intervention experiment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001531,purified MHC direct binding assay measuring half life of a MHC:ligand complex using fluorescence detection,half life|purified MHC/direct/fluorescence|min,A purified MHC ligand half life of binding determination assay that uses fluorescence detection to measure direct ligand binding.,false,,,http://purl.obolibrary.org/obo/OBI_0001990|http://purl.obolibrary.org/obo/OBI_0001499,,,,,,,,,,,,,,,,,,,A purified MHC ligand half life of binding determination assay that uses fluorescence detection to measure direct ligand binding.,IEDB,,,,,,purified MHC direct binding assay measuring half life of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001531,,,,,,,,,,,,,,,,,,,,,,,,half life|purified MHC/direct/fluorescence|min,,,,,,,,,,,,,,,,,,,,,,purified MHC direct binding assay measuring half life of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/GO_0006955,immune response,,Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.,false,,,http://purl.obolibrary.org/obo/GO_0050896,,,,,,,,,,,,,,,,,,,Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.,,,,,,,immune response,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0006955,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,immune response,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001763,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-C motif) ligand 22 production by T cells,CCL22/MDC release|RNA/DNA detection,An assay of epitope specific chemokine (C-C motif) ligand 22 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001777,,,,,,,,,,,,,,,,,,,An assay of epitope specific chemokine (C-C motif) ligand 22 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-C motif) ligand 22 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001763,,,,,,,,,,,,,,,,,,,,,,,,CCL22/MDC release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-C motif) ligand 22 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001300,cytometric bead array assay measuring epitope specific interleukin-2 production by T cells,IL-2 release|cytometric bead array,An assay of epitope specific interleukin-2 production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001445,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-2 production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific interleukin-2 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001300,,,,,,,,,,,,,,,,,,,,,,,,IL-2 release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific interleukin-2 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0400010,argon ion laser,,"An argon-ion laser is an ion laser that uses argon ions as the lasing medium. These lasers are used primarily to emit light at wave lengths of 458 nm, 488 nm or 514.5 nm, though it is possible to use them to emit several wavelengths of blue and green light. Argon-ion lasers can emit light at many different wave lenghts, and excite a number of different flourochromes.",false,,,http://purl.obolibrary.org/obo/OBI_0400060,,,,,,,,,,,,,,,,,,,"An argon-ion laser is an ion laser that uses argon ions as the lasing medium. These lasers are used primarily to emit light at wave lengths of 458 nm, 488 nm or 514.5 nm, though it is possible to use them to emit several wavelengths of blue and green light. Argon-ion lasers can emit light at many different wave lenghts, and excite a number of different flourochromes.",John Quinn|http://en.wikipedia.org/wiki/Laser#Gas_lasers,,,,,,argon ion laser,,argon ion laser in a cytometer,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400010,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,argon ion laser,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000482,normal phase column,,A normal phase column is a chromatography column in which the stationary phase is more polar than the mobile phase. Its counterpart is the reversed phase column.,false,,,http://purl.obolibrary.org/obo/OBI_0000038,,,,,,,,,,,,,,,,,,,A normal phase column is a chromatography column in which the stationary phase is more polar than the mobile phase. Its counterpart is the reversed phase column.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01097,,,,,,normal phase column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000482,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,normal phase column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001220,cell culture analyte detection bioassay measuring epitope specific interleukin-10 production by T cells,IL-10 release|bioassay,An assay of epitope specific interleukin-10 production by T cells that uses a cell culture analyte detection bioassay.,false,,,http://purl.obolibrary.org/obo/OBI_0001209,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-10 production by T cells that uses a cell culture analyte detection bioassay.,IEDB,,,,,,cell culture analyte detection bioassay measuring epitope specific interleukin-10 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001220,,,,,,,,,,,,,,,,,,,,,,,,IL-10 release|bioassay,,,,,,,,,,,,,,,,,,,,,,cell culture analyte detection bioassay measuring epitope specific interleukin-10 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0400109,homogenizer,,"A homogenizer is an instrument for the homogenization of various types of material, such as tissue, plant, food, soil, and many others.",false,,,http://purl.obolibrary.org/obo/OBI_0001033,,,,,,,,,,,,,,,,,,,"A homogenizer is an instrument for the homogenization of various types of material, such as tissue, plant, food, soil, and many others.",http://en.wikipedia.org/wiki/Homogenizer,,,,,,homogenizer,,"mortar, blender",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/OBI_0000377,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400109,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,homogenizer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Melanie Courtot|Trish Whetzel,,
http://purl.obolibrary.org/obo/OBI_0001756,ELISPOT assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells,CXCL9/MIG release|ELISPOT,An assay of epitope specific chemokine (C-X-C motif) ligand 9 production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001459,,,,,,,,,,,,,,,,,,,An assay of epitope specific chemokine (C-X-C motif) ligand 9 production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001756,,,,,,,,,,,,,,,,,,,,,,,,CXCL9/MIG release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001659,flow cytometry assay measuring binding of a B cell epitope:antibody complex,qualitative binding|flow cytometry,A B cell epitope qualitative binding to antibody assay that uses a flow cytometry assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001703|http://purl.obolibrary.org/obo/OBI_0001499,,,,,,,,,,,,,,,,,,,A B cell epitope qualitative binding to antibody assay that uses a flow cytometry assay.,IEDB,,,,,,flow cytometry assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001659,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|flow cytometry,,,,,,,,,,,,,,,,,,,,,,flow cytometry assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001290,transcription profiling by array design,,A study design that identifies forms and abundance of transcripts in the genome using microarray technology.,false,,,http://purl.obolibrary.org/obo/OBI_0001430,,,,,,,,,,,,,,,,,,,A study design that identifies forms and abundance of transcripts in the genome using microarray technology.,MO_533 transcript_identification_design,,,,,,transcription profiling by array design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001331,,,,,,,,,,,,,,,,OBI:0001290,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,transcription profiling by array design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0400116,thermal cycler,Polymerase_Chain_Reaction_ machine|DNA_amplifier|thermocycler|PCR_machine,An instrument that is capable of repeatedly altering and maintaining specific temperatures for defined periods of time.,false,,,http://purl.obolibrary.org/obo/OBI_0000967|http://purl.obolibrary.org/obo/OBI_0001034,,,,Polymerase_Chain_Reaction_ machine|DNA_amplifier|thermocycler|PCR_machine,,,,,,,,,,,,,,,An instrument that is capable of repeatedly altering and maintaining specific temperatures for defined periods of time.,MO,,,,,,thermal cycler,,Piko(tm) 96-well Thermal Cycler,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/OBI_0000370|http://purl.obolibrary.org/obo/OBI_0000401,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400116,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,thermal cycler,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Melanie Courtot|Trish Whetzel,,
http://purl.obolibrary.org/obo/OBI_0001973,ion semiconductor chip,ion semiconductor|ion integrated circuit|ion chip,"An ion detector that is organized as an electronic circuit whose components, such as transistors and resistors, are etched or deposited on a single slice of semiconductor material to produce a chip. The specific chip detects ion charge induced when an ion passes by or hits a surface.",false,,,http://purl.obolibrary.org/obo/OBI_0000364,,,,ion semiconductor|ion integrated circuit|ion chip,,,,,,,,,,,,,,,"An ion detector that is organized as an electronic circuit whose components, such as transistors and resistors, are etched or deposited on a single slice of semiconductor material to produce a chip. The specific chip detects ion charge induced when an ion passes by or hits a surface.",http://www.thefreedictionary.com/Semiconductor+chip,,,,,"Issue Tracker: #776
https://sourceforge.net/p/obi/obi-terms/776/",ion semiconductor chip,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001973,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ion semiconductor chip,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Sagar Jain,,
http://purl.obolibrary.org/obo/OBI_0000865,96-well neutralization assay,microneutralization assay,A serum neutralization of viral infectivity assay which done in a 96-well plate.,false,,,http://purl.obolibrary.org/obo/OBI_0000872,,,,microneutralization assay,,,,,,,,,,,,,"MC: 20100217: microneutralization is used by the influenza community, to refer to a nutralizationassay at a smaller scale. However smaller is difficult to define accurately, and we therefore chose a label being more specific.",,A serum neutralization of viral infectivity assay which done in a 96-well plate.,,,,,,,96-well neutralization assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000865,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,96-well neutralization assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person: Bjoern Peters|person: Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0001418,dose response design,,A study design that examines the relationship between the size of the administered dose and the extent of the response.,false,,,http://purl.obolibrary.org/obo/OBI_0000951,,,,,,,,,,,,,,,,,,,A study design that examines the relationship between the size of the administered dose and the extent of the response.,MO_485 dose_response_design,,,,,,dose response design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000015,,,,,,,,,,,,,,,,OBI:0001418,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,dose response design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000112,specimen role,,a role borne by a material entity that is gained during a specimen collection process and that can be realized by use of the specimen in an investigation,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,,,a role borne by a material entity that is gained during a specimen collection process and that can be realized by use of the specimen in an investigation,OBI,,,,,"blood taken from animal: animal continues in study, whereas blood has role specimen.
something taken from study subject, leaves the study and becomes the specimen.|parasite example
- when parasite in people we study people, people are subjects and parasites are specimen
- when parasite extracted, they become subject in the following study
specimen can later be subject.|22Jun09.  The definition includes whole organisms, and can include a human.  The link between specimen role and study subject role has been removed.  A specimen taken as part of a case study is not considered to be a population representative, while a specimen taken as representing a population, e.g. person taken from a cohort, blood specimen taken from an animal) would be considered a population representative and would also bear material sample role.|Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation.",specimen role,,liver section; a portion of a culture of cells; a nemotode or other animal once no longer a subject (generally killed); portion of blood from a patient.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000112,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,specimen role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP:  Role Branch,,
http://purl.obolibrary.org/obo/OBI_0001029,OH-radical structure mapping assay,MOHCA assay|single nucleotide resolution mapping assay using OH-radical probe|OH footprinting assay,a single-nucleotide-resolution nucleic acid structure mapping assay which uses hydroxyl radical as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,false,,,http://purl.obolibrary.org/obo/OBI_0001017,,http://purl.obolibrary.org/obo/OBI_0000441,,MOHCA assay|single nucleotide resolution mapping assay using OH-radical probe|OH footprinting assay,,,,,,,,,,,,,,,a single-nucleotide-resolution nucleic acid structure mapping assay which uses hydroxyl radical as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,RNA ontology,,,,,,OH-radical structure mapping assay,,PMID:2501870,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001029,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OH-radical structure mapping assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/NCBITaxon_117571,Euteleostomi,bony vertebrates,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_7742,,,,bony vertebrates,,,,,,,,,,,,,,,,,,,,,,Euteleostomi,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:117571,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Euteleostomi,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200186,error correction objective,,"An error correction objective is a data transformation objective where the aim is to remove (correct for) erroneous contributions arising from the input data, or the transformation itself.",false,,,http://purl.obolibrary.org/obo/OBI_0200168,,,,,,,,,,,,,,,,,,,"An error correction objective is a data transformation objective where the aim is to remove (correct for) erroneous contributions arising from the input data, or the transformation itself.",PERSON: James Malone,,,,,,error correction objective,,Application of a multiple testing correction method,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200186,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,error correction objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"James Malone, Helen Parkinson",,
http://purl.obolibrary.org/obo/OBI_0000445,mass measurement assay,,a process to determine the mass of an evaluant|Philippe Rocca-Serra,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,http://purl.obolibrary.org/obo/OBI_0000441,,,,,,,,,,,,,,,,,a process to determine the mass of an evaluant,OBI,,,,,,mass measurement assay,,The patients was weighed and mass was determined to be 47 kilograms,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000414,,,OBI:0000445,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,,,,,,,,,,,,,,,,,,,,,,,,,,,mass measurement assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0000928,material combination function,,A material separation function is a function that decreases the resolution between two or more material entities.,false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,A material separation function is a function that decreases the resolution between two or more material entities.,OBI,,,,,,material combination function,,A stirrer has a material combination function,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000928,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,material combination function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0000411,cloning vector role,,"A material to be added role played by a small, self-replicating DNA or RNA molecule - usually a plasmid or chromosome - and realized in a process whereby foreign DNA or RNA is inserted into the vector during the process of cloning.",false,,,http://purl.obolibrary.org/obo/OBI_0000319,,,,,,,,,,,,,,,,,,,"A material to be added role played by a small, self-replicating DNA or RNA molecule - usually a plasmid or chromosome - and realized in a process whereby foreign DNA or RNA is inserted into the vector during the process of cloning.",,,,,,JZ: related tracker: https://sourceforge.net/p/obi/obi-terms/102/,cloning vector role,,pBluescript plays the role of a cloning vector,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000411,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cloning vector role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0000207,health care provider role,health care provider,a worker role of providing medical care either within or outside the study timeline,false,,,http://purl.obolibrary.org/obo/OBI_0000116,,,,health care provider,,,,,,,,,,,,,,,a worker role of providing medical care either within or outside the study timeline,,,,,,,health care provider role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000207,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,health care provider role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Jennifer Fostel,,
http://purl.obolibrary.org/obo/IAO_0000182,obsolete_survival curve,,A survival curve is a report graph which is a graphical representation of data where the percentage of survival is plotted as a function of time.,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,A survival curve is a report graph which is a graphical representation of data where the percentage of survival is plotted as a function of time.,WEB: http://www.graphpad.com/www/book/survive.htm,,,,,,obsolete_survival curve,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,IAO:0000182,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_survival curve,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:James Malone|PERSON:Chris Stoeckert|PERSON:Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0001222,ELISA measuring epitope specific RANTES production by T cells,CCL5/RANTES release|ELISA,An assay of epitope specific RANTES production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001232,,,,,,,,,,,,,,,,,,,An assay of epitope specific RANTES production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific RANTES production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001222,,,,,,,,,,,,,,,,,,,,,,,,CCL5/RANTES release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific RANTES production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000383,transfer function,,A transfer function is a function to displace a material from one location to another.,false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,A transfer function is a function to displace a material from one location to another.,,,,,,,transfer function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000383,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,transfer function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bill Bug|Daniel Schober|Frank Gibson|Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0001149,gene knock in,,"a genetic transformation that involves the insertion of a protein coding cDNA sequence at a particular locus in an organism's chromosome. Typically, this is done in mice since the technology for this process is more refined, and because mouse embryonic stem cells are easily manipulated. The difference between knock-in technology and transgenic technology is that a knock-in involves a gene inserted into a specific locus, and is a ""targeted"" insertion.",false,,,http://purl.obolibrary.org/obo/OBI_0600043,,,,,,,,,,,,,,,,,,,"a genetic transformation that involves the insertion of a protein coding cDNA sequence at a particular locus in an organism's chromosome. Typically, this is done in mice since the technology for this process is more refined, and because mouse embryonic stem cells are easily manipulated. The difference between knock-in technology and transgenic technology is that a knock-in involves a gene inserted into a specific locus, and is a ""targeted"" insertion.",WEB: http://en.wikipedia.org/wiki/Gene_Knock-in|MO_437 gene_knock_in,,,,,,gene knock in,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001149,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,gene knock in,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0600059,DNA transduction,,a genetic transformation which relies on the use of lysogenic infection to transfer DNA sequences into an organism,false,,,http://purl.obolibrary.org/obo/OBI_0600043,,,,,,,,,,,,,,,,,,,a genetic transformation which relies on the use of lysogenic infection to transfer DNA sequences into an organism,OBI branch derived,,,,,,DNA transduction,,The transfer of a recombinant bacterial plasmid into E.coli to facilitate amplification of a specific protein,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/NCBITaxon_10239,,,,OBI:0600059,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNA transduction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Kevin Clancy,,
http://purl.obolibrary.org/obo/OBI_1110157,ELISA measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells,GM-CSF release|ELISA,An assay of epitope specific granulocyte macrophage colony stimulating factor production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001233,,,,,,,,,,,,,,,,,,,An assay of epitope specific granulocyte macrophage colony stimulating factor production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110157,,,,,,,,,,,,,,,,,,,,,,,,GM-CSF release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0600017,detection of molecular label,,an assay that detects the presence or a quality of a molecular label which is a proxy for the detection of the molecular target to which the label is attached,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,http://purl.obolibrary.org/obo/OBI_0000441,,,,,,,,,,,,,,,,,an assay that detects the presence or a quality of a molecular label which is a proxy for the detection of the molecular target to which the label is attached,"OBI developer call, 3-12-12",,,,,,detection of molecular label,,Determination of the amount of phycoerytherin label present in a cell population stained with anti-CD8-PE in order to determine the percentage of CD8+ T cells present,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001936,,,,OBI:0600017,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,detection of molecular label,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/REO_0000171,,,,,,,,,,,,,,,,PERSON:Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_0000310,adverse event trigger,,revisit?,false,,,http://purl.obolibrary.org/obo/IAO_0000001,,,,,,,,,,,,,,,,,,,revisit?,OBI branch derived,,,,,,adverse event trigger,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000310,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,adverse event trigger,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0000201,radioactivity detection,,"An assay that measures the amount of radiation in the radioactive spectrum (alpha, beta or gamma rays) emitted from an input material.",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,"An assay that measures the amount of radiation in the radioactive spectrum (alpha, beta or gamma rays) emitted from an input material.",IEDB,,,,,,radioactivity detection,,Placing the evaluant input material close to a scintillation counter which emits light upon being hit with alpha/beta/gamma radiation and counting the frequency of light blasts to determine the radioactivity of the input material.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000201,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,radioactivity detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PlanAndPlannedProcess Branch, IEDB",,
http://purl.obolibrary.org/obo/OBI_0400110,hybridization chamber,,A device which is used to maintain constant contact of a liquid on an array.  This can be either a glass vial or slide.,false,,,http://purl.obolibrary.org/obo/OBI_0000967|http://purl.obolibrary.org/obo/OBI_0001034,,,,,,,,,,,,,,,,,,,A device which is used to maintain constant contact of a liquid on an array.  This can be either a glass vial or slide.,MO_563 hybridization_chamber,,,,,,hybridization chamber,,Glass Array Hybridization Cassette,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000370|http://purl.obolibrary.org/obo/OBI_0000401,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,hybridization chamber,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Trish Whetzel,,
http://purl.obolibrary.org/obo/CHEBI_42191,ethylenediaminetetraacetic acid,,A polyamino carboxylic acid that has formula C10H16N2O8.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,A polyamino carboxylic acid that has formula C10H16N2O8.,,,,,,,ethylenediaminetetraacetic acid,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:42191,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,ethylenediaminetetraacetic acid,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001109,bead array reader,,A device that is used to acquire and image bead array data.,false,,,http://purl.obolibrary.org/obo/OBI_0000398,,,,,,,,,,,,,,,,,,,A device that is used to acquire and image bead array data.,PERSON: Erik Segerdell,,,,,,bead array reader,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453|http://purl.obolibrary.org/obo/OBI_0000397,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001109,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,bead array reader,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0000667,obsolete MHC multimer staining assay,MHC tetramer assay|MHC tetramer/multimer staining,An MHC multimer assay is an assay that detects T cells capable of binding the MHC:ligand complexes present in the multimer. The multimer is fluorescently labelled. The T cells bound to multimers are counted in a flow cytometer,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,MHC tetramer assay,,,,,,,,,,,,,,,An MHC multimer assay is an assay that detects T cells capable of binding the MHC:ligand complexes present in the multimer. The multimer is fluorescently labelled. The T cells bound to multimers are counted in a flow cytometer,IEDB,,,,,,obsolete MHC multimer staining assay,,Measuring T cells that are specific for the SYFPEITHI peptide when presented by the murine MHC molecule H-2 Kd by staining them with a tetramer of peptide loaded MHC complexes.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000227,,,,,,,,,,,,,,,,,,OBI:0000667,,,,,,,,,,,,,,,,,,,,,,,,MHC tetramer/multimer staining,,,,,,,,,,,,,,,,,,,,,,obsolete MHC multimer staining assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,http://purl.obolibrary.org/obo/OBI_1110179,
http://purl.obolibrary.org/obo/GO_0002250,adaptive immune response,,"An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory).",false,,,http://purl.obolibrary.org/obo/GO_0006955,,,,,,,,,,,,,,,,,,,"An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory).",,,,,,,adaptive immune response,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0002250,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,adaptive immune response,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001364,genetic alteration information,,"a genetic characteristics information that is about known changes or the lack thereof from the genetic background, including allele information, duplication, insertion, deletion, etc.",false,,,http://purl.obolibrary.org/obo/OBI_0001404,,,,,,,,,,,,,,,,,,,"a genetic characteristics information that is about known changes or the lack thereof from the genetic background, including allele information, duplication, insertion, deletion, etc.",Group: OBI group,,,,,"proposed and discussed on San Diego OBI workshop, March 2011",genetic alteration information,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001364,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,genetic alteration information,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Group: OBI group,,
http://purl.obolibrary.org/obo/OBI_0000158,eSource document,,"an eSource document is a digital document consisting of a logical collection of Source data and other eSource documents that can be presented in an ordered way and capture the time of completion, change, and any signatures",false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,,,,,,,,,,,,,,,,"an eSource document is a digital document consisting of a logical collection of Source data and other eSource documents that can be presented in an ordered way and capture the time of completion, change, and any signatures",article-without-pmid-or-doi:CDISCglossary,,,,,,eSource document,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000158,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,eSource document,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0001327,biological activity assay measuring epitope specific lymphotoxin A production by T cells,lymphotoxin A/TNFb release|biological activity,A T cell epitope specific cytokine production assay that detects lymphotoxin A production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_0001400,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects lymphotoxin A production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific lymphotoxin A production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001327,,,,,,,,,,,,,,,,,,,,,,,,lymphotoxin A/TNFb release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific lymphotoxin A production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001435,DNA methylation profiling by high throughput sequencing design,,A study design in which the methylation state of DNA is determined and is compared between samples using high throughput sequencing technology.,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,A study design in which the methylation state of DNA is determined and is compared between samples using high throughput sequencing technology.,GROUP: ArrayExpress production team,,,,,,DNA methylation profiling by high throughput sequencing design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001234,,,,,,,,,,,,,,,,OBI:0001435,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNA methylation profiling by high throughput sequencing design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001211,ex vivo design,,"A study design where all or part of an organism is removed and studied in vitro, e.g. part of a mouse is removed and cultured in vitro. A cell culture with an established cell line is an in vitro experiment.",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A study design where all or part of an organism is removed and studied in vitro, e.g. part of a mouse is removed and cultured in vitro. A cell culture with an established cell line is an in vitro experiment.",MO_808 ex_vivo_design,,,,,,ex vivo design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001211,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ex vivo design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/CHEBI_33375,gadolinium atom,,A lanthanoid atom that has formula Gd.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,A lanthanoid atom that has formula Gd.,,,,,,,gadolinium atom,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:33375,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,gadolinium atom,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_1110016,adaptive immune effector function,,"A function realized as an immune response, which inheres in a T cell, B cell or antibody which derives from or is produced by a cell with prior antigen experience.",false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,"A function realized as an immune response, which inheres in a T cell, B cell or antibody which derives from or is produced by a cell with prior antigen experience.",IEDB,,,,,,adaptive immune effector function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110016,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,adaptive immune effector function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001093,microtome knife sharpener,,A device that is used to sharpen knives used in microtomy.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A device that is used to sharpen knives used in microtomy.,PERSON: Erik Segerdell,,,,,,microtome knife sharpener,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000379,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001093,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,microtome knife sharpener,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001595,X-ray crystallography assay determining the 3D structure of a MHC:ligand complex,3D structure|x-ray crystallography|angstroms,A MHC binding 3D structure determination of MHC molecule:epitope complex assay that uses an X-ray crystallography assay.,false,,,http://purl.obolibrary.org/obo/OBI_0002050,,,,,,,,,,,,,,,,,,,A MHC binding 3D structure determination of MHC molecule:epitope complex assay that uses an X-ray crystallography assay.,IEDB,,,,,,X-ray crystallography assay determining the 3D structure of a MHC:ligand complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001595,,,,,,,,,,,,,,,,,,,,,,,,3D structure|x-ray crystallography|angstroms,,,,,,,,,,,,,,,,,,,,,,X-ray crystallography assay determining the 3D structure of a MHC:ligand complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/UBERON_0002358,peritoneum,,"A serous membrane that lines the peritoneal cavity[VHOG,modified].",false,,,http://purl.obolibrary.org/obo/CARO_0000055,,,,,,,,,,,,,,,,,,,"A serous membrane that lines the peritoneal cavity[VHOG,modified].",,,,,,,peritoneum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UBERON:0002358,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uberon.owl,,,,,,,,,,,,,,,,,,,peritoneum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001409,cell cycle design,,"A study design that assays events that occur in relation to the cell cycle, which is the period between the formation of a cell, by division of its mother cell and the time when the cell itself divides to form two daughter cells.",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A study design that assays events that occur in relation to the cell cycle, which is the period between the formation of a cell, by division of its mother cell and the time when the cell itself divides to form two daughter cells.",MO_822 cell_cycle_design,,,,,,cell cycle design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001409,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cell cycle design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001255,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-5 production by T cells,IL-5 release|RNA/DNA detection,An assay of epitope specific interleukin-5 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001230,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-5 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-5 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001255,,,,,,,,,,,,,,,,,,,,,,,,IL-5 release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-5 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0200089,multiple testing correction method,multiple testing procedure,A multiple testing correction method is a hypothesis test performed simultaneously on M > 1 hypotheses.  Multiple testing procedures produce a set of rejected hypotheses that is an estimate for the set of false null hypotheses while controlling for a suitably define Type I error rate,false,,,http://purl.obolibrary.org/obo/OBI_0000668,,,,multiple testing procedure,,,,,,,,,,,,,,,A multiple testing correction method is a hypothesis test performed simultaneously on M > 1 hypotheses.  Multiple testing procedures produce a set of rejected hypotheses that is an estimate for the set of false null hypotheses while controlling for a suitably define Type I error rate,"PAPER: Dudoit, Sandrine and van der Laan, Mark J. (2008) Multiple Testing Procedures with Applications to Genomics.  New York: Springer , p. 9-10.",,,,,,multiple testing correction method,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200089,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,multiple testing correction method,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Monnie McGee,,
http://purl.obolibrary.org/obo/IAO_0000029,numeral,,A symbol that denotes a number.,false,,,http://purl.obolibrary.org/obo/IAO_0000028,,,,,,,,,,,,,,,,,,,A symbol that denotes a number.,,,,,,,numeral,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000029,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,numeral,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Jonathan Rees,,
http://purl.obolibrary.org/obo/IAO_0000027,data item,data,"a data item is an information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements.",false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,data,,,,,,,,,,,,,,,"a data item is an information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements.",,,,,,"2014-03-31: See discussion at http://odontomachus.wordpress.com/2014/03/30/aboutness-objects-propositions/|JAR: datum     -- well, this will be very tricky to define, but maybe some 
information-like stuff that might be put into a computer and that is 
meant, by someone, to denote and/or to be interpreted by some 
process... I would include lists, tables, sentences... I think I might 
defer to Barry, or to Brian Cantwell Smith

JAR: A data item is an approximately justified approximately true approximate belief|2009-03-16: data item deliberatly ambiguous: we merged data set and datum to be one entity, not knowing how to define singular versus plural. So data item is more general than datum.|2/2/2009 Alan and Bjoern discussing FACS run output data. This is a data item because it is about the cell population. Each element records an event and is typically further composed a set of measurment data items that record the fluorescent intensity stimulated by one of the lasers.|2009-03-16: removed datum as alternative term as datum specifically refers to singular form, and is thus not an exact synonym.",data item,,"Data items include counts of things, analyte concentrations, and statistical summaries.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000027,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,data item,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Jonathan Rees|PERSON: Chris Stoeckert|PERSON: Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0001105,scanning force microscope,,A microscope that forms images of surfaces using a physical probe that scans the specimen.,false,,,http://purl.obolibrary.org/obo/OBI_0400169,,,,,,,,,,,,,,,,,,,A microscope that forms images of surfaces using a physical probe that scans the specimen.,http://en.wikipedia.org/wiki/Scanning_probe_microscopy,,,,,,scanning force microscope,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001105,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,scanning force microscope,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/PR_000023089,DNA ligase,ligase,A protein that is a translation product of the Escherichia coli K-12 ligA gene or a 1:1 ortholog thereof.,false,,,http://purl.obolibrary.org/obo/PR_000000001|http://purl.obolibrary.org/obo/OBI_0000427,,,,ligase,,,,,,,,,,,,,,,A protein that is a translation product of the Escherichia coli K-12 ligA gene or a 1:1 ortholog thereof.,,,,,,Definition defined by OBI developers: an enzyme that covalently joins two compatible pieces of DNA through the cleavage of an ATP molecule,DNA ligase,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/GO_0003824,,,,,,,,,,,,,,,,,,,,,,,,,,,,PR:000023089,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pr.owl,,,,,,,,,,,,,,,,,,,DNA ligase,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0100060,cultured cell population,cell culture sample,"A processed material comprised of a collection of cultured cells that has been continuously maintained together in culture and shares a common propagation history.|The extent of a 'cultured cell population' is restricted only in that all cell members must share a propagation history (ie be derived through a common lineage of passages from an initial culture). In being defined in this way, this class can be used to refer to the populations that researchers actually use in the practice of science - ie are the inputs to culturing, experimentation, and sharing. The cells in such populations will be a relatively uniform population as they have experienced similar selective pressures due to their continuous co-propagation. And this population will also have a single passage number, again owing to their common passaging history. Cultured cell populations represent only a collection of cells (ie do not include media, culture dishes, etc), and include populations of cultured unicellular organisms or cultured multicellular organism cells. They can exist under active culture, stored in a quiescent state for future use, or applied experimentally.",false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,cell culture sample,,,,,,,,,,,,,,,A processed material comprised of a collection of cultured cells that has been continuously maintained together in culture and shares a common propagation history.,PERSON:Matthew Brush,,,,,"2013-6-5 MHB: This OBI class was formerly called 'cell culture', but label changed and definition updated following CLO alignment efforts in spring 2013, during which the intent of this class was clarified to refer to portions of a culture or line rather than a complete cell culture or line.",cultured cell population,,"A cultured cell population applied in an experiment: ""293 cells expressing TrkA were serum-starved for 18 hours and then neurotrophins were added for 10 min before cell harvest.""  (Lee, Ramee, et al. ""Regulation of cell survival by secreted proneurotrophins."" Science 294.5548 (2001): 1945-1948).

A cultured cell population maintained in vitro: ""Rat cortical neurons from 15 day embryos are grown in dissociated cell culture and maintained in vitro for 8–12 weeks"" (Dichter, Marc A. ""Rat cortical neurons in cell culture: culture methods, cell morphology, electrophysiology, and synapse formation."" Brain Research 149.2 (1978): 279-293).",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,http://purl.obolibrary.org/obo/CL_0000010,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0100060,,,,,,,,,,,,,,,,,,"The extent of a 'cultured cell population' is restricted only in that all cell members must share a propagation history (ie be derived through a common lineage of passages from an initial culture). In being defined in this way, this class can be used to refer to the populations that researchers actually use in the practice of science - ie are the inputs to culturing, experimentation, and sharing. The cells in such populations will be a relatively uniform population as they have experienced similar selective pressures due to their continuous co-propagation. And this population will also have a single passage number, again owing to their common passaging history. Cultured cell populations represent only a collection of cells (ie do not include media, culture dishes, etc), and include populations of cultured unicellular organisms or cultured multicellular organism cells. They can exist under active culture, stored in a quiescent state for future use, or applied experimentally.",,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0600024,,,cultured cell population,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_0200168,correction objective,,"A correction objective is a data transformation objective where the aim is to correct for error, noise or other impairments to the input of the data transformation or derived from the data transformation itself",false,,,http://purl.obolibrary.org/obo/OBI_0200166,,,,,,,,,,,,,,,,,,,"A correction objective is a data transformation objective where the aim is to correct for error, noise or other impairments to the input of the data transformation or derived from the data transformation itself",PERSON: Melanie Courtot|PERSON: James Malone,,,,,,correction objective,,Type I error correction,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200168,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,correction objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0001086,radiation measurement device,,A device that consists of a radiosensitive detector and a means of recording the effects of radiation on the detector.,false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,A device that consists of a radiosensitive detector and a means of recording the effects of radiation on the detector.,PERSON: Erik Segerdell,,,,,,radiation measurement device,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453|http://purl.obolibrary.org/obo/OBI_0000368,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001086,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,radiation measurement device,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/CHEBI_59052,"1,1-dihydroxy-3-ethoxy-2-butanone",,A butanone derivative having two hydroxy substituents at the 1-position and an ethoxy substituent at the 3-position.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,A butanone derivative having two hydroxy substituents at the 1-position and an ethoxy substituent at the 3-position.,,,,,,,"1,1-dihydroxy-3-ethoxy-2-butanone",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:59052,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,"1,1-dihydroxy-3-ethoxy-2-butanone",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000050,obsolete_platform,,A platform is an object_aggregate that is the set of instruments and software needed to perform a process. definition_source: OBI.,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,"rem1: We decided at the Philly workshop that consumables do not include reagents.
FG: we could actully add a relation to platform which would be ""has_part some instrument""
DS: Sounds fine to me, with the restriction that I would assume a min. cardinality of 2 to be applicable for this crossproduct, so at least 2 instruments make it a platform... at least one is not  enough
AR:has_part is transitive, and transitive properties can't have  cardinality constraints in OWL-DL. We can always put this particular  constraint in the owl-full file.

We need to make this a defined class when the class software is in the ontology|suggested for deprecation https://sourceforge.net/tracker/index.php?func=detail&aid=2881353&group_id=177891&atid=886178",,A platform is an object_aggregate that is the set of instruments and software needed to perform a process. definition_source: OBI.,OBI Instrument branch,,,,,,obsolete_platform,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,OBI:0000050,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_platform,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI Instrument branch,,
http://purl.obolibrary.org/obo/OBI_0000806,material maintenance objective,,An objective specification maintains some or all of the qualities of a material over time.,false,,,http://purl.obolibrary.org/obo/IAO_0000005,,,,,,,,,,,,,,,,,,,An objective specification maintains some or all of the qualities of a material over time.,PERSON: Bjoern Peters,,,,,,material maintenance objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000806,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,material maintenance objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001873,number of errors,,"a data item that is the number of times that a given process failed, as an integer",false,,,http://purl.obolibrary.org/obo/IAO_0000027|http://purl.obolibrary.org/obo/OBI_0001933,,,,,,,,,,,,,,,,,,,"a data item that is the number of times that a given process failed, as an integer","PRS, AGB",,,,,,number of errors,,"Gigascience. 2012 Dec 27;1(1):18. doi: 10.1186/2047-217X-1-18.
PMID: 23587118. see table2",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001873,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000015,,,,,,,,,,,,,,,,number of errors,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Alejandra Gonzalez-Beltran|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001604,purified MHC direct binding assay measuring 50% dissociation of binding temperature [Tm] of a MHC:ligand complex using fluorescence detection,50% dissociation temperature|purified MHC/direct/fluorescence|°C,A purified MHC binding assay that uses fluorescence detection to measure the 50% dissociation of binding temperature of direct ligand binding.,false,,,http://purl.obolibrary.org/obo/OBI_0001555|http://purl.obolibrary.org/obo/OBI_0001499,,,,,,,,,,,,,,,,,,,A purified MHC binding assay that uses fluorescence detection to measure the 50% dissociation of binding temperature of direct ligand binding.,IEDB,,,,,,purified MHC direct binding assay measuring 50% dissociation of binding temperature [Tm] of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001501,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001566,,,OBI:0001604,,,,,,,,,,,,,,,,,,,,,,,,50% dissociation temperature|purified MHC/direct/fluorescence|°C,,,,,,,,,,,,,,,,,,,,,,purified MHC direct binding assay measuring 50% dissociation of binding temperature [Tm] of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/GO_0071924,chemokine (C-C motif) ligand 22 production,,"The appearance of chemokine (C-C motif) ligand 22 (CCL22) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0032602,,,,,,,,,,,,,,,,,,,"The appearance of chemokine (C-C motif) ligand 22 (CCL22) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,chemokine (C-C motif) ligand 22 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0071924,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,chemokine (C-C motif) ligand 22 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200199,gas chromatography mass spectrometry,,"Gas chromatography mass spectrometry is a data transformation combining mass spectrometry and  
gas chromatography for the qualitative as well as quantitative  
determinations of compounds.",false,,,http://purl.obolibrary.org/obo/OBI_0200085,,http://purl.obolibrary.org/obo/OBI_0200197,,,,,,,,,,,,,,,,,"Gas chromatography mass spectrometry is a data transformation combining mass spectrometry and  
gas chromatography for the qualitative as well as quantitative  
determinations of compounds.",PERSON: Tina Boussard,,,,,,gas chromatography mass spectrometry,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200199,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,gas chromatography mass spectrometry,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Tina Boussard|PERSON: James Malone,,
http://purl.obolibrary.org/obo/OBI_0001621,longitude coordinate measurement datum,longitude|Specimen Collection Location - Longitude,A measurement datum that is the measure of the longitude coordinate of a site.,false,,,http://purl.obolibrary.org/obo/IAO_0000109,,,,longitude,,,,,,,,,,,,,,,A measurement datum that is the measure of the longitude coordinate of a site.,NIAID GSCID-BRC metadata working group,,,,,,longitude coordinate measurement datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001621,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,longitude coordinate measurement datum,,,,,,Specimen Collection Location - Longitude,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001635,antibody binding detection by fluorescence quenching,,"A binding assay in which affinity is measured by detecting a change in fluorescence (usually quenching) that occurs upon binding of the antibody to the ligand. The fluorescent signal that is affected by binding is either from an exogenous fluorophore attached to the ligand, or is the intrisic fluorescence of aromatic (tryptophan) residues on the binding site of the antibody (no conjugated fluorophore necessary) or, less commonly, on the ligand binding region (epitope).",false,,,http://purl.obolibrary.org/obo/OBI_0001979,,,,,,,,,,,,,,,,,,,"A binding assay in which affinity is measured by detecting a change in fluorescence (usually quenching) that occurs upon binding of the antibody to the ligand. The fluorescent signal that is affected by binding is either from an exogenous fluorophore attached to the ligand, or is the intrisic fluorescence of aromatic (tryptophan) residues on the binding site of the antibody (no conjugated fluorophore necessary) or, less commonly, on the ligand binding region (epitope).",IEDB,,,,,,antibody binding detection by fluorescence quenching,,"The binding affinity of Fab 4-4-20 for the fluorescein molecule was determined using the fluorescence quenching assay, by placing the Fab and the fluorescein together in a well and measuring the fluorescence after each addition of increasing concentrations of the Fab (PMID: 8637844). ",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001501,,,,,,,,,,,,,,,,OBI:0001635,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,antibody binding detection by fluorescence quenching,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001798,intracellular cytokine staining assay measuring epitope specific interleukin-9 production by T cells,IL-9 release|ICS,An assay of epitope specific interleukin-9 production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001253,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-9 production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-9 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001798,,,,,,,,,,,,,,,,,,,,,,,,IL-9 release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-9 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000525,splitless GC injector,,"Injected sample enters column immediately (while split valve to split vent is closed). Here a sample is introduced into a heated small chamber via a syringe through a septum - the heat facilitates volatilization of the sample and sample matrix. The carrier gas then either sweeps the entirety (splitless mode) or a portion (split mode) of the sample into the column. In split mode, a part of the sample/carrier gas mixture in the injection chamber is exhausted through the split vent.",false,,,http://purl.obolibrary.org/obo/OBI_0000504,,,,,,,,,,,,,,,,,,,"Injected sample enters column immediately (while split valve to split vent is closed). Here a sample is introduced into a heated small chamber via a syringe through a septum - the heat facilitates volatilization of the sample and sample matrix. The carrier gas then either sweeps the entirety (splitless mode) or a portion (split mode) of the sample into the column. In split mode, a part of the sample/carrier gas mixture in the injection chamber is exhausted through the split vent.",WEB:<http://en.wikipedia.org/wiki/Gas_chromatography>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01060,,,,,,splitless GC injector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000525,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,splitless GC injector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0002028,SAGE ditag library preparation,,"A library preparation in which tags identifiying transcripts are created, ligated to form ditags, amplified, concatemerized and ligated into a vector to create a library.
",false,,,http://purl.obolibrary.org/obo/OBI_0000711,,,,,,,,,,,,,,,,,,,"A library preparation in which tags identifiying transcripts are created, ligated to form ditags, amplified, concatemerized and ligated into a vector to create a library.
",PMID:15905473,,,,,Related tracker:https://sourceforge.net/p/obi/obi-terms/720/,SAGE ditag library preparation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002028,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,SAGE ditag library preparation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0000172,parameter threshold,,"A measurement datum measuring the minimal signal that must be detected to generate an electrical event, as compared to the maximal detected signal in a flow cytometer instrument. The datum has a qualitative role",false,,,http://purl.obolibrary.org/obo/IAO_0000109,,,,,,,,,,,,,,,,,,,"A measurement datum measuring the minimal signal that must be detected to generate an electrical event, as compared to the maximal detected signal in a flow cytometer instrument. The datum has a qualitative role",Submitted by the Flow Cytometry community in DigitalEntity-FlowCytometry-2007-03-30.txt,,,,,,parameter threshold,,"0.01, 0.03",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000172,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,parameter threshold,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Kevin Clancy,,
http://purl.obolibrary.org/obo/OBI_0000684,specimen collection objective,,A objective specification to obtain a material entity for potential use as an input during an investigation.,false,,,http://purl.obolibrary.org/obo/IAO_0000005,,,,,,,,,,,,,,,,,,,A objective specification to obtain a material entity for potential use as an input during an investigation.,Bjoern Peters,,,,,,specimen collection objective,,The objective to collect bits of excrement in the rainforest. The objective to obtain a blood sample from a patient.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000684,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,specimen collection objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001359,ELISA measuring epitope specific interleukin-8 production by T cells,IL-8 release|ELISA,An assay of epitope specific interleukin-8 production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001218,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-8 production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific interleukin-8 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001359,,,,,,,,,,,,,,,,,,,,,,,,IL-8 release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific interleukin-8 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_1110037,assay measuring binding of a T cell epitope:MHC:TCR complex,T cell binding|any method,An immune epitope assay that detects T cell epitope recognition.,false,,,http://purl.obolibrary.org/obo/OBI_1110128,,,,,,,,,,,,,,,,,,,An immune epitope assay that detects T cell epitope recognition.,IEDB,,,,,,assay measuring binding of a T cell epitope:MHC:TCR complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110037,,,,,,,,,,,,,,,,,,,,,,,,T cell binding|any method,,,,,,,,,,,,,,,,,,,,,,assay measuring binding of a T cell epitope:MHC:TCR complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001544,cell lysate MHC competitive binding assay measuring equilibrium dissociation constant [KD] of a MHC:ligand complex using radioactivity detection,dissociation constant KD|lysate MHC/competitive/radioactivity|nM,A cell lysate MHC ligand binding equilibrium dissociation constant (KD) determination assay that uses radioactivity detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation.,false,,,http://purl.obolibrary.org/obo/OBI_0001988|http://purl.obolibrary.org/obo/OBI_0001491,,,,,,,,,,,,,,,,,,,A cell lysate MHC ligand binding equilibrium dissociation constant (KD) determination assay that uses radioactivity detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation.,IEDB,,,,,,cell lysate MHC competitive binding assay measuring equilibrium dissociation constant [KD] of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001544,,,,,,,,,,,,,,,,,,,,,,,,dissociation constant KD|lysate MHC/competitive/radioactivity|nM,,,,,,,,,,,,,,,,,,,,,,cell lysate MHC competitive binding assay measuring equilibrium dissociation constant [KD] of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000286,precipitate,precipited material,a precipitate is a material entity which is output of a precipitation process,false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,precipited material,,,,,,,,,,,,,,,a precipitate is a material entity which is output of a precipitation process,GROUP: OBI Biomaterial Branch,,,,,,precipitate,,Physicochemical properties and antibacterial activity of the precipitate of vancomycin and ceftazidime: implications in the management of endophthalmitis. Retina. 2008 Feb;28(2):320-5. PMID: 18301038,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000286,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0600034,,,precipitate,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0002065,cytometric bead array assay measuring epitope specific granzyme B release by T cells,granzyme B release|cytometric bead array,A T cell epitope specific granzyme B release assay that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001436,,,,,,,,,,,,,,,,,,,A T cell epitope specific granzyme B release assay that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific granzyme B release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002065,,,,,,,,,,,,,,,,,,,,,,,,granzyme B release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific granzyme B release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001616,specimen identifier,specimen ID|Specimen ID,A CRID symbol denotes a specimen and used to distinguish one specimen from another in an investigation.,false,,,http://purl.obolibrary.org/obo/IAO_0000577,,,,specimen ID,,,,,,,,,,,,,,,A CRID symbol denotes a specimen and used to distinguish one specimen from another in an investigation.,NIAID GSCID-BRC metadata working group,,,,,,specimen identifier,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001616,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,specimen identifier,,,,,,Specimen ID,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001549,cell bound MHC competitive binding assay measuring equilibrium dissociation constant [KD] of a MHC:ligand complex using radioactivity detection,dissociation constant KD|cellular MHC/competitive/radioactivity|nM,A cell bound MHC ligand binding equilibrium dissociation constant (KD) determination assay that uses radioactivity detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation.,false,,,http://purl.obolibrary.org/obo/OBI_0001988|http://purl.obolibrary.org/obo/OBI_0001491,,,,,,,,,,,,,,,,,,,A cell bound MHC ligand binding equilibrium dissociation constant (KD) determination assay that uses radioactivity detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation.,IEDB,,,,,,cell bound MHC competitive binding assay measuring equilibrium dissociation constant [KD] of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001549,,,,,,,,,,,,,,,,,,,,,,,,dissociation constant KD|cellular MHC/competitive/radioactivity|nM,,,,,,,,,,,,,,,,,,,,,,cell bound MHC competitive binding assay measuring equilibrium dissociation constant [KD] of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0302876,dissolved material entity,,A material entity that has been going through a process of being put into solution,false,,,http://purl.obolibrary.org/obo/BFO_0000040|http://purl.obolibrary.org/obo/OBI_0000576,,,,,,,,,,,,,,,,,,,A material entity that has been going through a process of being put into solution,,,,,,,dissolved material entity,,Salt molecules that have been mixed into water,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302876,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,dissolved material entity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra|Person:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0600016,pooling specimens,sample pooling,physical combination of several instances of like material,false,,,http://purl.obolibrary.org/obo/OBI_0000652,,http://purl.obolibrary.org/obo/OBI_0000686,,sample pooling,,,,,,,,,,,,,like' is one of the things that you should be controling for in a well-designed experiment. The instances of material need to have the same class.,,physical combination of several instances of like material,OBI branch derived,,,,,,pooling specimens,,"http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=104564; Combining spleens of 20 mice, Combining supernatant from a cell culture obtained at different time points",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100051,http://purl.obolibrary.org/obo/OBI_0302716,,,OBI:0600016,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,pooling specimens,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0000951,compound treatment design,,an intervention design in which the treatment is the administration of a compound,false,,,http://purl.obolibrary.org/obo/OBI_0500000|http://purl.obolibrary.org/obo/OBI_0000115,,,,,,,,,,,,,,,,,,,an intervention design in which the treatment is the administration of a compound,MO_555 compound_treatment_design,,,,,"This is meant to include all kinds of material administrations, including vaccinations, chemical compounds etc.",compound treatment design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000951,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,compound treatment design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_1110056,epitope specific IL-2 release by T cells,,A biological process where T cells produce IL-2 resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0032623|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,,,A biological process where T cells produce IL-2 resulting from the recognition of a T cell epitope.,IEDB,,,,,,epitope specific IL-2 release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110056,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific IL-2 release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000879,random primed DNA labeling,,a labeling in which random primers are used to uniformly label input DNA,false,,,http://purl.obolibrary.org/obo/OBI_0600038,,,,,,,,,,,,,,,,,,,a labeling in which random primers are used to uniformly label input DNA,"PMID: 6312838. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Feinberg AP, Vogelstein B. Anal Biochem. 1983 Jul 1;132(1):6-13.",,,,,need to add Klenow subunit of DNA polymerase I under material entity,random primed DNA labeling,,"PMID: 8713846. Random primed 32P-labeling of DNA. Smith DR.
Methods Mol Biol. 1996;58:27-9.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000879,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,random primed DNA labeling,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Philippe Rocca-Serra|Person: Bjoern Peters
Person: Chris Stoeckert",,
http://purl.obolibrary.org/obo/OBI_0400017,BioSorter500,,"A BioSorter500 is a flow_cytometer_sorter manufactured by Union Biometrica. It includes analog electronics, 488/514 nm multi-line Argon-ion laser for fluorescence and a light stabilized 670 nm forward scatter laser for extinction and time-of-flight. It has filters and PMTs for 3 fluorescent parameters and photodiodes for scatter, time of flight, and extinction. The flow cell is quartz cuvette. The BioSorterTM 500 is an instrument for analyzing and sorting objects from 100-250 microns in diameter and less than 2mm in length.",false,,,http://purl.obolibrary.org/obo/OBI_0400099,,,,,,,,,,,,,,,,,,,"A BioSorter500 is a flow_cytometer_sorter manufactured by Union Biometrica. It includes analog electronics, 488/514 nm multi-line Argon-ion laser for fluorescence and a light stabilized 670 nm forward scatter laser for extinction and time-of-flight. It has filters and PMTs for 3 fluorescent parameters and photodiodes for scatter, time of flight, and extinction. The flow cell is quartz cuvette. The BioSorterTM 500 is an instrument for analyzing and sorting objects from 100-250 microns in diameter and less than 2mm in length.",http://www.unionbio.com/products/BioSorter.html,,,,,,BioSorter500,,BioSorter 500 at TSRI Flow Cytometry Core Facility,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400017,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BioSorter500,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0200131,quantitative node degree calculation,,A node quality calculation in which an input data set describing object nodes and quantitative relationship edges between object nodes is used to sum all of the quantitative relationships of an individual object node.,false,,,http://purl.obolibrary.org/obo/OBI_0200129,,,,,,,,,,,,,,,,,,,A node quality calculation in which an input data set describing object nodes and quantitative relationship edges between object nodes is used to sum all of the quantitative relationships of an individual object node.,PERSON: Richard Scheuermann,,,,,,quantitative node degree calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200131,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,quantitative node degree calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Richard Scheuermann,,
http://purl.obolibrary.org/obo/OBI_0200189,merging objective,combining objective,A merging objective is a data transformation objective in which the data transformation has the aim of performing a union of two or more sets.,false,,,http://purl.obolibrary.org/obo/OBI_0200166,,,,combining objective,,,,,,,,,,,,,,,A merging objective is a data transformation objective in which the data transformation has the aim of performing a union of two or more sets.,PERSON: Data Transformation Branch,,,,,,merging objective,,merging of columns from two different data sets,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200189,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,merging objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0000404,gel dryer,,A gel dryer is a device which has the function to contain and to control the contained environment to facilitate the drying of gels,false,,,http://purl.obolibrary.org/obo/OBI_0000967|http://purl.obolibrary.org/obo/OBI_0001034,,,,,,,,,,,,,,,,,,,A gel dryer is a device which has the function to contain and to control the contained environment to facilitate the drying of gels,sep:00094,,,,,,gel dryer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000370|http://purl.obolibrary.org/obo/OBI_0000401,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000404,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,gel dryer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Frank Gibson,,
http://purl.obolibrary.org/obo/OBI_1110047,cultured CD3+ T cell population,CD3+ T cell culture sample,A T cell population characterized by expressing the CD3 molecule on its surface.,false,,,http://purl.obolibrary.org/obo/OBI_0001875,,,,CD3+ T cell culture sample,,,,,,,,,,,,,,,A T cell population characterized by expressing the CD3 molecule on its surface.,IEDB,,,,,,cultured CD3+ T cell population,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110047,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cultured CD3+ T cell population,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0200064,centroid mass spectrum,centroid mass spectrum calculation|centroiding,"A centroid mass spectrum is a data transformation in which many points are used to delineate a mass spectral peak, is converted into mass-centroided data by a data compression algorithm. The centroided mass peak is located at the weighted center of mass of the profile peak. The normalized area of the peak provides the mass intensity data.",false,,,http://purl.obolibrary.org/obo/OBI_0200085,,http://purl.obolibrary.org/obo/OBI_0200197,,centroid mass spectrum calculation|centroiding,,,,,,,,,,,,,,,"A centroid mass spectrum is a data transformation in which many points are used to delineate a mass spectral peak, is converted into mass-centroided data by a data compression algorithm. The centroided mass peak is located at the weighted center of mass of the profile peak. The normalized area of the peak provides the mass intensity data.",centroid mass spectrum,,,,,,centroid mass spectrum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200064,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,centroid mass spectrum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Tina Hernandez-Boussard,,
http://purl.obolibrary.org/obo/OBI_0400053,helium neon ion laser,,"A helium-neon laser (HeNe) is an ion laser that uses helium and neon gas-ions as lasing medium. HeNe lasers emit at 543 nm and 633 nm most commonly and can also be used at 543, 594, and 611 nm.",false,,,http://purl.obolibrary.org/obo/OBI_0400060,,,,,,,,,,,,,,,,,,,"A helium-neon laser (HeNe) is an ion laser that uses helium and neon gas-ions as lasing medium. HeNe lasers emit at 543 nm and 633 nm most commonly and can also be used at 543, 594, and 611 nm.",John Quinn|http://en.wikipedia.org/wiki/Laser#Gas_lasers,,,,,,helium neon ion laser,,A helium neon laser can by used to irradiate cells in a flow cytometer.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400053,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,helium neon ion laser,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Daniel Schober,,
http://purl.obolibrary.org/obo/GO_0008134,GO_0008134,,,false,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0008134,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/BFO_0000008,temporal region,,,false,,,http://purl.obolibrary.org/obo/BFO_0000003,,,,,,,TemporalRegion,t-region,,,,,,,,,,,,,,,,,Temporal region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the mereological sum of a temporal instant and a temporal interval that doesn't overlap the instant. In this case the resultant temporal region is neither 0-dimensional nor 1-dimensional,temporal region,A temporal region is an occurrent entity that is part of time as defined relative to some reference frame. (axiom label in BFO2 Reference: [100-001]),,,,,,,,,(forall (r) (if (TemporalRegion r) (occupiesTemporalRegion r r))) // axiom label in BFO2 CLIF: [119-002] |(forall (x y) (if (and (TemporalRegion x) (occurrentPartOf y x)) (TemporalRegion y))) // axiom label in BFO2 CLIF: [101-001] |(forall (x) (if (TemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [100-001] ,Every temporal region t is such that t occupies_temporal_region t. (axiom label in BFO2 Reference: [119-002])|All parts of temporal regions are temporal regions. (axiom label in BFO2 Reference: [101-001]),,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000008,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,temporal region,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/SO_0000001,region,sequence|primary structure of sequence macromolecule,A sequence_feature with an extent greater than zero. A nucleotide region is composed of bases and a polypeptide region is composed of amino acids.,false,,,http://purl.obolibrary.org/obo/BFO_0000031,,,,sequence|primary structure of sequence macromolecule,,,,,,,,,,,,,,,A sequence_feature with an extent greater than zero. A nucleotide region is composed of bases and a polypeptide region is composed of amino acids.,,,,,,,region,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,SO:0000001,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/so.owl,,,,,,,,,,,,,,,,,,,region,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000533,affinity column,,An affinity column is a chromatography column that is used in affinity chromatography. Differences in the affinity of molecules to be separated to a stationary phase are used for discriminate retention.,false,,,http://purl.obolibrary.org/obo/OBI_0000038,,,,,,,,,,,,,,,,,,,An affinity column is a chromatography column that is used in affinity chromatography. Differences in the affinity of molecules to be separated to a stationary phase are used for discriminate retention.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01094,,,,,,affinity column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000533,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,affinity column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0400065,light source,,"A light source is an optical subsystem that provides light for use in a distant area using a delivery system (e.g., fiber optics). Light sources may include one of a variety of lamps (e.g., xenon, halogen, mercury). Most light sources are operated from line power, but some may be powered from batteries. They are mostly used in endoscopic, microscopic, and other examination and/or in surgical procedures. The light source is part of the optical subsystem. In a flow cytometer the light source directs high intensity light at particles at the interrogation point. The light source in a flow cytometer is usually a laser.",false,,,http://purl.obolibrary.org/obo/OBI_0001032,,,,,,,,,,,,,,,,,,,"A light source is an optical subsystem that provides light for use in a distant area using a delivery system (e.g., fiber optics). Light sources may include one of a variety of lamps (e.g., xenon, halogen, mercury). Most light sources are operated from line power, but some may be powered from batteries. They are mostly used in endoscopic, microscopic, and other examination and/or in surgical procedures. The light source is part of the optical subsystem. In a flow cytometer the light source directs high intensity light at particles at the interrogation point. The light source in a flow cytometer is usually a laser.","Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253",,,,,,light source,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000367,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400065,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,light source,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elizabeth M. Goralczyk|John Quinn|Olga Tchuvatkina,,
http://purl.obolibrary.org/obo/OBI_0001384,cell culture analyte detection bioassay measuring epitope specific interleukin-3 production by T cells,IL-3 release|bioassay,An assay of epitope specific interleukin-3 production by T cells that uses a cell culture analyte detection bioassay.,false,,,http://purl.obolibrary.org/obo/OBI_0001406,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-3 production by T cells that uses a cell culture analyte detection bioassay.,IEDB,,,,,,cell culture analyte detection bioassay measuring epitope specific interleukin-3 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001384,,,,,,,,,,,,,,,,,,,,,,,,IL-3 release|bioassay,,,,,,,,,,,,,,,,,,,,,,cell culture analyte detection bioassay measuring epitope specific interleukin-3 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000820,activated partial thromboplastin time (aPTT) assay,,"An activated partial thromboplastin time (aPTT) assay is a an assay measuring the efficacy of both the 'intrinsic' (now referred to as the contact activation pathway) and the common coagulation pathways. In order to activate the intrinsic pathway, phospholipid, an activator (such as silica, celite, kaolin, ellagic acid), and calcium (to reverse the anticoagulant effect of the oxalate) are mixed into the plasma sample . The time is measured until a thrombus (clot) forms.",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,,"An activated partial thromboplastin time (aPTT) assay is a an assay measuring the efficacy of both the 'intrinsic' (now referred to as the contact activation pathway) and the common coagulation pathways. In order to activate the intrinsic pathway, phospholipid, an activator (such as silica, celite, kaolin, ellagic acid), and calcium (to reverse the anticoagulant effect of the oxalate) are mixed into the plasma sample . The time is measured until a thrombus (clot) forms.",WEB:http://en.wikipedia.org/wiki/Partial_thromboplastin_time@2008/10/06,,,,,2009/10/18 Alan Ruttenberg. This assay was added during the fucoidan use case exercise but still needs to be fleshed out. Only the AT-III assay has more carefully specified inputs and outputs,activated partial thromboplastin time (aPTT) assay,,PMID:19696660#The activated partial thromboplastin time (aPTT) was determined using Dade Actin FSL activated PTT reagent.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000820,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,activated partial thromboplastin time (aPTT) assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/CHEBI_37989,Cy5 dye,,,false,,,http://purl.obolibrary.org/obo/REO_0000280,,,,,,,,,,,,,,,,,,,,,,,,,,Cy5 dye,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/REO_0000171,,,,,,,,,,,,CHEBI:37989,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,Cy5 dye,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000622,gel permeation column,,A gel permeation column is a chromatography column which is used in gel permeation chromatography and which employs as the stationary phase a swollen gel made by polymerizing and cross-linking styrene in the presence of a diluent which is a nonsolvent for the styrene polymer. The polymer to be analyzed is introduced at the top of the column and then is elutriated with a solvent. The polymer molecules diffuse through the gel at rates depending on their molecular size.,false,,,http://purl.obolibrary.org/obo/OBI_0000038,,,,,,,,,,,,,,,,,,,A gel permeation column is a chromatography column which is used in gel permeation chromatography and which employs as the stationary phase a swollen gel made by polymerizing and cross-linking styrene in the presence of a diluent which is a nonsolvent for the styrene polymer. The polymer to be analyzed is introduced at the top of the column and then is elutriated with a solvent. The polymer molecules diffuse through the gel at rates depending on their molecular size.,WEB:<http://composite.about.com/od/glossaries/l/bldef_g2419.htm>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01103,,,,,,gel permeation column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000622,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,gel permeation column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0500007,randomized complete block design,,A randomized complete block design is_a study design which assigns randomly treatments to block. The number of units per block equals the number of treatment so each block receives each treatment exactly once (hence the qualifier 'complete'). The design was originally devised from field trials used in agronomy and agriculture. The analysis assumes that there is no interaction between block and treatment. The method was then used in other settings So The randomised complete block design is a design in which the subjects are matched according to a variable which the experimenter wishes to control. The subjects are put into groups (blocks) of the same size as the number of treatments. The members of each block are then randomly assigned to different treatment groups.,false,,,http://purl.obolibrary.org/obo/OBI_0000115,,,,,,,,,,,,,,,,,,,A randomized complete block design is_a study design which assigns randomly treatments to block. The number of units per block equals the number of treatment so each block receives each treatment exactly once (hence the qualifier 'complete'). The design was originally devised from field trials used in agronomy and agriculture. The analysis assumes that there is no interaction between block and treatment. The method was then used in other settings So The randomised complete block design is a design in which the subjects are matched according to a variable which the experimenter wishes to control. The subjects are put into groups (blocks) of the same size as the number of treatments. The members of each block are then randomly assigned to different treatment groups.,http://www.tufts.edu/~gdallal/ranblock.htm,,,,,,randomized complete block design,,"http://www.stats.gla.ac.uk/steps/glossary/anova.html,(A researcher is carrying out a study of the effectiveness of four different skin creams for the treatment of a certain skin disease. He has eighty subjects and plans to divide them into 4 treatment groups of twenty subjects each. Using a randomised blocks& design, the subjects are assessed and put in blocks of four according to how severe their skin condition is; the four most severe cases are the first block, the next four most severe cases are the second block, and so on to the twentieth block. The four &members of each block are then randomly assigned, one to each of the four treatment groups. http://www.stats.gla.ac.uk/steps/glossary/anova.html#rbd))",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500007,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,randomized complete block design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000940,optical microscope,,A microscope that produces an image of an object by targeting it with an electro-magnetic beam in the visible frequency range,false,,,http://purl.obolibrary.org/obo/OBI_0400169,,,,,,,,,,,,,,,,,,,A microscope that produces an image of an object by targeting it with an electro-magnetic beam in the visible frequency range,,,,,,,optical microscope,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000940,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,optical microscope,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Bjoern Peters,,
http://purl.obolibrary.org/obo/CHEBI_37972,phosphorus-32 atom,,The radioactive isotope of phosphorus with relative atomic mass 31.973907 and half-life of 14.26 days.,false,,,http://purl.obolibrary.org/obo/CHEBI_33250,,,,,,,,,,,,,,,,,,,The radioactive isotope of phosphorus with relative atomic mass 31.973907 and half-life of 14.26 days.,,,,,,,phosphorus-32 atom,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/REO_0000171,,,,,,,,,,,,CHEBI:37972,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,phosphorus-32 atom,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000993,service provision objective,,An objective which is fulfilled by the provision of some service e.g. a training service,false,,,http://purl.obolibrary.org/obo/IAO_0000005,,,,,,,,,,,,,,,,,,,An objective which is fulfilled by the provision of some service e.g. a training service,OBI,,,,,,service provision objective,,A sequencing centre has a service provision objective,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000993,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,service provision objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0001791,ELISPOT assay measuring epitope specific lymphotoxin A production by T cells,lymphotoxin A/TNFb release|ELISPOT,An assay of epitope specific lymphotoxin A production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001327|http://purl.obolibrary.org/obo/OBI_0001272,,,,,,,,,,,,,,,,,,,An assay of epitope specific lymphotoxin A production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific lymphotoxin A production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001791,,,,,,,,,,,,,,,,,,,,,,,,lymphotoxin A/TNFb release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific lymphotoxin A production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001130,vacuum oven,,A device that heats materials in a vacuum.,false,,,http://purl.obolibrary.org/obo/OBI_0000967|http://purl.obolibrary.org/obo/OBI_0001034,,,,,,,,,,,,,,,,,,,A device that heats materials in a vacuum.,PERSON: Erik Segerdell,,,,,,vacuum oven,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000370|http://purl.obolibrary.org/obo/OBI_0000379|http://purl.obolibrary.org/obo/OBI_0000371,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001130,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,vacuum oven,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001941,contig N50,,"N50 statistic computed for the contigs produced by the assembly process. A contig N50 is calculated by first ordering every contig by length from longest to shortest. Next, starting from the longest contig, the lengths of each contig are summed, until this running sum equals one-half of the total length of all contigs in the assembly. The contig N50 of the assembly is the length of the shortest contig in this list.",false,,,http://purl.obolibrary.org/obo/OBI_0001940,,,,,,,,,,,,,,,,,,,"N50 statistic computed for the contigs produced by the assembly process. A contig N50 is calculated by first ordering every contig by length from longest to shortest. Next, starting from the longest contig, the lengths of each contig are summed, until this running sum equals one-half of the total length of all contigs in the assembly. The contig N50 of the assembly is the length of the shortest contig in this list.",adapted from: nature:http://www.nature.com/nrg/journal/v13/n5/box/nrg3174_BX1.html,,,,,,contig N50,,"Gigascience. 2012 Dec 27;1(1):18. doi: 10.1186/2047-217X-1-18.
PMID: 23587118. 

""Here, the contig and scaffold N50 of the YH genome were ~20.9 kbp and ~22 Mbp""",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001941,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,contig N50,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Alejandra Gonzalez-Beltran|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0200051,principal components analysis dimensionality reduction,pca data reduction,A principal components analysis dimensionality reduction is a dimensionality reduction achieved by applying principal components analysis and by keeping low-order principal components and excluding higher-order ones.,false,,,http://purl.obolibrary.org/obo/OBI_0200050,,,,pca data reduction,,,,,,,,,,,,,,,A principal components analysis dimensionality reduction is a dimensionality reduction achieved by applying principal components analysis and by keeping low-order principal components and excluding higher-order ones.,PERSON: Elisabetta Manduchi|PERSON: James Malone|PERSON: Melanie Courtot,,,,,,principal components analysis dimensionality reduction,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200051,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,principal components analysis dimensionality reduction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Melanie Courtot|Elisabetta Manduchi|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001502,epitope specific perforin production by T cells,,"The production of perforin, an immune mediator molecule involved in T cell degranulation,  resulting from the recognition of a T cell epitope.",false,,,http://purl.obolibrary.org/obo/GO_0035944,,,,,,,,,,,,,,,,,,,"The production of perforin, an immune mediator molecule involved in T cell degranulation,  resulting from the recognition of a T cell epitope.",,,,,,"Should be linked to a GO process, which will be requested by IEDB team. Along with granzyme B production, should be tied to T cell degranulation",epitope specific perforin production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001502,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific perforin production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Bjoern Peters, Randi Vita",,
http://purl.obolibrary.org/obo/OBI_0001203,detection of specific nucleic acids with complementary probes assay measuring epitope specific transforming growth factor-beta production by T cells,TGFb release|RNA/DNA detection,An assay of epitope specific transforming growth factor-beta production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001264,,,,,,,,,,,,,,,,,,,An assay of epitope specific transforming growth factor-beta production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific transforming growth factor-beta production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001203,,,,,,,,,,,,,,,,,,,,,,,,TGFb release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific transforming growth factor-beta production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000260,plan,,A plan is a realizable entity that is the inheres in a bearer who is committed to realizing it as a planned process.,false,,,http://purl.obolibrary.org/obo/BFO_0000017,,,,,,,,,,,,,,,,,,,A plan is a realizable entity that is the inheres in a bearer who is committed to realizing it as a planned process.,branch derived,,,,,"This class is included to make clear how the plan specification, the plan, and the planned process relate. OBI will however only subclass and work under the 'plan specification', and 'planned process' class, as we want to avoid to get deep into discussions of 'intend' etc.",plan,,The plan of researcher X to perform an experiment according to a protocol.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000260,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,plan,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"AR, BP, JM, MC, PRS",,
http://purl.obolibrary.org/obo/OBI_0001500,coelution assay measuring MHC ligand processing and presentation using T cell recognition of HPLC fractionated eluate compared to synthetic ligand,ligand presentation|coelution,A MHC ligand processing and presentation assay in which an HPL chromatography is run to separate an input mixture of ligands eluted from MHC into fractions. These fractions are tested for recognition by T cells and compared to the recognition of a synthetic ligand that is presumed to be the recognized epitope. Identical HPLC fractionation and T cell recognition patterns confirm that the specific ligand was presented by MHC molecules. ,false,,,http://purl.obolibrary.org/obo/OBI_1110125,,,,,,,,,,,,,,,,,,,A MHC ligand processing and presentation assay in which an HPL chromatography is run to separate an input mixture of ligands eluted from MHC into fractions. These fractions are tested for recognition by T cells and compared to the recognition of a synthetic ligand that is presumed to be the recognized epitope. Identical HPLC fractionation and T cell recognition patterns confirm that the specific ligand was presented by MHC molecules. ,IEDB,,,,,,coelution assay measuring MHC ligand processing and presentation using T cell recognition of HPLC fractionated eluate compared to synthetic ligand,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_1110037,,,,,,,,,,,,,,,,OBI:0001500,,,,,,,,,,,,,,,,,,,,,,,,ligand presentation|coelution,,,,,,,,,,,,,,,,,,,,,,coelution assay measuring MHC ligand processing and presentation using T cell recognition of HPLC fractionated eluate compared to synthetic ligand,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000167,electronic case report form,,An electronic case report form is a digital document used to record all of the protocol required information to be reported for each trial subject. An eCRF has the property that it can be audited and compliant with requirements of 21 CFR Part 11.,false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,,,,,,,,,,,,,,,,An electronic case report form is a digital document used to record all of the protocol required information to be reported for each trial subject. An eCRF has the property that it can be audited and compliant with requirements of 21 CFR Part 11.,CDISC glossary,,,,,,electronic case report form,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000167,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,electronic case report form,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0000676,reduced dimension data set,,A data set that is produced as the output of a data vector reduction data transformation and consists of producing a data set which has fewer vectors than the input data set.,false,,,http://purl.obolibrary.org/obo/IAO_0000100,,,,,,,,,,,,,,,,,,,A data set that is produced as the output of a data vector reduction data transformation and consists of producing a data set which has fewer vectors than the input data set.,,,,,,,reduced dimension data set,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000676,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,reduced dimension data set,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: James Malone|PERSON: Monnie McGee,,
http://purl.obolibrary.org/obo/OBI_0200020,homogeneous polynomial transformation,,A homogeneous polynomial transformation is a polynomial transformation where all the term of the polynomial have the same degree.,false,,,http://purl.obolibrary.org/obo/OBI_0200093,,,,,,,,,,,,,,,,,,,A homogeneous polynomial transformation is a polynomial transformation where all the term of the polynomial have the same degree.,WEB: http://mathworld.wolfram.com/HomogeneousPolynomial.html,,,,,,homogeneous polynomial transformation,,"a*x, with a non-zero, is a homogeneous polynomial of degree 1 in 1 variable, a*x^2, with a non-zero, is a homogeneous polynomial of degree 2 in 1 variable; a_1*x_1+...+a_n*x_n, with at least one of the a_i's non-zero, is a homogeneous polynomial of degree one in n variables; a*x_n^3+b*x_1*x_2*x_3, with at least one of a and b non-zero, is a homogeneous polynomial of degree 3 in n variables.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200020,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,homogeneous polynomial transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0001760,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-X-C motif) ligand 13 production by T cells,CXCL13/BLC release|RNA/DNA detection,An assay of epitope specific chemokine (C-X-C motif) ligand 13 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001779,,,,,,,,,,,,,,,,,,,An assay of epitope specific chemokine (C-X-C motif) ligand 13 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-X-C motif) ligand 13 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001760,,,,,,,,,,,,,,,,,,,,,,,,CXCL13/BLC release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-X-C motif) ligand 13 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0200160,generalized family wise error rate correction method,gFWER correction,"A generalized FWER correction method is a multiple testing procedure that controls the probability of at least k+1 false positives, where k is a user-supplied integer.",false,,,http://purl.obolibrary.org/obo/OBI_0200089,,http://purl.obolibrary.org/obo/OBI_0000791,,gFWER correction,,,,,,,,,,,,,,,"A generalized FWER correction method is a multiple testing procedure that controls the probability of at least k+1 false positives, where k is a user-supplied integer.","Dudoit, Sandrine and van der Laan, Mark J. (2008) Multiple Testing Procedures with Applications to Genomics.  New York: Springer , p. 19",,,,,,generalized family wise error rate correction method,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200160,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,generalized family wise error rate correction method,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Monnie McGee,,
http://purl.obolibrary.org/obo/NCBITaxon_7227,Drosophila melanogaster,fruit fly,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_197562,,,,fruit fly,,,,,,,,,,,,,,,,,,,,,,Drosophila melanogaster,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:7227,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Drosophila melanogaster,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001107,tissue embedding station,,A device that is used to perform paraffin embedding of tissue specimens.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A device that is used to perform paraffin embedding of tissue specimens.,PERSON: Erik Segerdell,,,,,,tissue embedding station,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000379,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001107,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,tissue embedding station,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/NCBITaxon_33208,NCBITaxon_33208,,,false,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:33208,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000741,topologically preserved clustered data set,,"A clustered data set in which the topology, i.e. the spatial properties between data points, is preserved from the original input data from which it was derived.",false,,,http://purl.obolibrary.org/obo/OBI_0000648,,,,,,,,,,,,,,,,,,,"A clustered data set in which the topology, i.e. the spatial properties between data points, is preserved from the original input data from which it was derived.",PERSON: James Malone,,,,,,topologically preserved clustered data set,,the output data set generated from a self-organizing map.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000741,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,topologically preserved clustered data set,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0000436,needle,,"a needle is a sharp, hollow device used to penetrate tissue or soft material. When attached to a syringe. it allows delivery of a specific volume of liquid or gaseous mixture.",false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,"a needle is a sharp, hollow device used to penetrate tissue or soft material. When attached to a syringe. it allows delivery of a specific volume of liquid or gaseous mixture.",OBI Instrument,,,,,,needle,,"Ovarian carcinoma presenting with axillary lymph node metastasis: A case diagnosed by fine-needle aspiration and brief review of the literature.
Diagn Cytopathol. 2008 Oct 16. PMID: 18925569",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000383,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000436,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,needle,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000948,oscilloscope,,"A device that measures and displayes signal voltages, usually as a two-dimensional graph of one or more electrical potential differences (vertical axis) plotted as a function of time or of some other voltage (horizontal axis).",false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,"A device that measures and displayes signal voltages, usually as a two-dimensional graph of one or more electrical potential differences (vertical axis) plotted as a function of time or of some other voltage (horizontal axis).",http://en.wikipedia.org/wiki/Oscilloscope,,,,,,oscilloscope,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000948,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,oscilloscope,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0002050,3D structure determining assay of a MHC:ligand complex,3D structure|any method,A MHC:ligand binding assay that uses a 3D structure determination of bound complex assay.,false,,,http://purl.obolibrary.org/obo/OBI_1110126|http://purl.obolibrary.org/obo/OBI_0001145,,,,,,,,,,,,,,,,,,,A MHC:ligand binding assay that uses a 3D structure determination of bound complex assay.,IEDB,,,,,,3D structure determining assay of a MHC:ligand complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002050,,,,,,,,,,,,,,,,,,,,,,,,3D structure|any method,,,,,,,,,,,,,,,,,,,,,,3D structure determining assay of a MHC:ligand complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001399,epitope specific interleukin-22 production by T cells,,A process of interleukin-22 production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0032626|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of interleukin-22 production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific interleukin-22 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001399,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific interleukin-22 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0400153,droplet sorter,,"A droplet sorter is part_of a flow cytometer sorter that converts the carrier fluid stream into individual droplets, and these droplets are directed into separate locations for recovery (enriching the original
sample for particles of interest based on qualities determined by gating) or disposal.",false,,,http://purl.obolibrary.org/obo/OBI_0000932,,,,,,,,,,,,,,,,,,,"A droplet sorter is part_of a flow cytometer sorter that converts the carrier fluid stream into individual droplets, and these droplets are directed into separate locations for recovery (enriching the original
sample for particles of interest based on qualities determined by gating) or disposal.",OBI Instrument branch,,,,,,droplet sorter,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000403,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400153,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,droplet sorter,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI Instrument branch,,
http://purl.obolibrary.org/obo/OBI_0001139,liquid chromatography instrument,,A chromatography device that dissolves a mixture in liquid mobile phase to separate the analyte to be measured from other molecules in the mixture and allows it to be isolated,false,,,http://purl.obolibrary.org/obo/OBI_0000048,,,,,,,,,,,,,,,,,,,A chromatography device that dissolves a mixture in liquid mobile phase to separate the analyte to be measured from other molecules in the mixture and allows it to be isolated,PERSON: Matthew Brush,,,,,,liquid chromatography instrument,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001139,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,liquid chromatography instrument,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Matthew Brush,,
http://purl.obolibrary.org/obo/IAO_0000572,documenting,,a planned process in which a document is created or added to by including the specified input in it.,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,,,a planned process in which a document is created or added to by including the specified input in it.,wikipedia http://en.wikipedia.org/wiki/Documenting,,,,,"6/11/9: Edited at OBI workshop. We need to be able identify a child form of information artifact which corresponds to something enduring (not brain like). This used to be restricted to physical document or digital entity as the output, but that excludes e.g. an audio cassette tape",documenting,,Recording the current temperature in a laboratory notebook. Writing a journal article. Updating a patient record in a database.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000030,http://purl.obolibrary.org/obo/IAO_0000310,,,IAO:0000572,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,documenting,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/CHEBI_59055,(S)-1-(4-bromoacetamidobenzyl)EDTA,,A tetracarboxylic acid consisting of ethylenediaminetetraacetic acid having a 4-bromoacetamidobenzyl group at the C1-position and (S)-configuration.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,A tetracarboxylic acid consisting of ethylenediaminetetraacetic acid having a 4-bromoacetamidobenzyl group at the C1-position and (S)-configuration.,,,,,,,(S)-1-(4-bromoacetamidobenzyl)EDTA,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:59055,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,(S)-1-(4-bromoacetamidobenzyl)EDTA,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000929,obsolete_training service provider role,,a service provider role which is realized by a servicer provider organization performing some training,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,a service provider role which is realized by a servicer provider organization performing some training,OBI,,,,,"obsolete during the San Diego workshop, March 2011
The reason is that we decided to pursue a different modeling approach for services keeping just the 'service consumer' and 'service provider' roles and differentiate just at the level of planned process offered a s service.",obsolete_training service provider role,,EBI provides training on databases and tools and has a training service provider role,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,OBI:0000929,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_training service provider role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0001439,epitope specific chemokine (C-X-C motif) ligand 9 production by T cells,,A process of chemokine (C-X-C motif) ligand 9 production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0035393|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of chemokine (C-X-C motif) ligand 9 production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific chemokine (C-X-C motif) ligand 9 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001439,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific chemokine (C-X-C motif) ligand 9 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000100,obsolete_role of being first subject treated,,First subject treated role is a study subject role borne by the subject realized in the application of the process specified in intervention study design with no previous study subject realizing the role prior in the study,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,First subject treated role is a study subject role borne by the subject realized in the application of the process specified in intervention study design with no previous study subject realizing the role prior in the study,OBI,,,,,first subject treated. First subject who receives the test article or placebo in a clinical trial.,obsolete_role of being first subject treated,,Rat 1A; first enrolled patient to receive treatment,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,OBI:0000100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_role of being first subject treated,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Role Branch,,
http://purl.obolibrary.org/obo/OBI_0500018,replicate design,,A replicate experimental design type is where a series of replicates are performed to evaluate reproducibility or as a pilot study to determine the appropriate number of replicates for a subsequent experiments.,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,A replicate experimental design type is where a series of replicates are performed to evaluate reproducibility or as a pilot study to determine the appropriate number of replicates for a subsequent experiments.,MO_885,,,,,,replicate design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500018,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,replicate design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra on behalf of MO,,
http://purl.obolibrary.org/obo/OBI_0001768,intracellular cytokine staining assay measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells,CCL1/TCA-3 release|ICS,An assay of epitope specific chemokine (C-C motif) ligand 1 production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001276,,,,,,,,,,,,,,,,,,,An assay of epitope specific chemokine (C-C motif) ligand 1 production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001768,,,,,,,,,,,,,,,,,,,,,,,,CCL1/TCA-3 release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001870,Illumina methylation BeadChip,,A BeadChip made for an analyte assay that generates information about DNA methylation.,false,,,http://purl.obolibrary.org/obo/OBI_0001869,,,,,,,,,,,,,,,,,,,A BeadChip made for an analyte assay that generates information about DNA methylation.,Penn Group,,,,,,Illumina methylation BeadChip,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001870,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Illumina methylation BeadChip,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng, Alan Ruttenberg",,
http://purl.obolibrary.org/obo/OBI_0000917,nasal swab specimen,,"A specimen obtained using a cotton swab on a stick, passed up the nostril to obtain a sample of
exudate and epithelial debris for microbiological or cellular examination.",false,,,http://purl.obolibrary.org/obo/OBI_0100051,,,,,,,,,,,,,,,,,,,"A specimen obtained using a cotton swab on a stick, passed up the nostril to obtain a sample of
exudate and epithelial debris for microbiological or cellular examination.",WEB: http://www.wpro.who.int/NR/rdonlyres/EFD2B9A7-2265-4AD0-BC98-97937B4FA83C/0/manualonanimalaidiagnosisandsurveillance.pdf,,,,,,nasal swab specimen,,type of sample used in the PCIRN influenza network,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000112,,,,,,,,,,,,OBI:0000917,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,nasal swab specimen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0000143,baseline participant role,baseline participant,a reference participant role which is realized by making the reference to qualities at the start of the study or intervention,false,,,http://purl.obolibrary.org/obo/OBI_0000220,,,,baseline participant,,,,,,,,,,,,,,,a reference participant role which is realized by making the reference to qualities at the start of the study or intervention,,,,,,,baseline participant role,,Subject at time = 0; subject before a stress test.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000143,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,baseline participant role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0302743,obsolete_liver,,"liver is an anatomical entity which constituent are mainly hepatocytes, which has a function of detoxification, hematopoietic center, glucose and fat metabolism management. liver is only found in animals , all Vertebrates and some families of invertebrates",true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,PRS: Test. added for evaluation and validation of possible imports from CARO (or other anatomical resources),,"liver is an anatomical entity which constituent are mainly hepatocytes, which has a function of detoxification, hematopoietic center, glucose and fat metabolism management. liver is only found in animals , all Vertebrates and some families of invertebrates",GROUP: OBI Biomaterial Branch,,,,,,obsolete_liver,,"PMID: 2104732. Caudate lobe of the liver: anatomy, embryology, and pathology.
AJR Am J Roentgenol. 1990 Jan;154(1):87-93.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000228,,,,,,,,,,,,,,,,,,OBI:0302743,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_liver,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000996,device creation objective,,an objective which aims to create a device with a specified function,false,,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,,,an objective which aims to create a device with a specified function,OBI,,,,,,device creation objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000996,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,device creation objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0001805,intracellular cytokine staining assay measuring epitope specific interleukin-7 production by T cells,IL-7 release|ICS,An assay of epitope specific interleukin-7 production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001587,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-7 production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-7 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001805,,,,,,,,,,,,,,,,,,,,,,,,IL-7 release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-7 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000221,vital dye role,vital dye,A dye role that is realized when used to detect live cells in an experiment,false,,,http://purl.obolibrary.org/obo/OBI_0000250,,,,vital dye,,,,,,,,,,,,,,,A dye role that is realized when used to detect live cells in an experiment,,,,,,2009-11-10. Tracker: https://sourceforge.net/tracker/?func=detail&aid=2893048&group_id=177891&atid=886178,vital dye role,,typtan blue has a vital dye,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000221,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,vital dye role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jennifer Fostel|Person: Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0001758,ELISPOT assay measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells,CCL4/MIP-1b release|ELISPOT,An assay of epitope specific chemokine (C-C motif) ligand 4 production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001345,,,,,,,,,,,,,,,,,,,An assay of epitope specific chemokine (C-C motif) ligand 4 production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001758,,,,,,,,,,,,,,,,,,,,,,,,CCL4/MIP-1b release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000010,fluorescent reporter intensity,,A measurement datum that represents the output of a scanner measuring the intensity value for each fluorescent reporter.,false,,,http://purl.obolibrary.org/obo/IAO_0000109,,,,,,,,,,,,,,,,,"From the DT branch: This term and definition were originally submitted by the community to our branch, but we thought they best fit DENRIE. However we see several issues with this. First of all the name 'probe' might not be used in OBI. Instead we have a 'reporter' role. Also, albeit the term 'probe intensity' is often used in communities such as the microarray one, the name 'probe' is ambiguous (some use it to refer to what's on the array, some use it to refer to what's hybed to the array). Furthermore, this concept could possibly be encompassed by combining different OBI terms, such as the roles of analyte, detector and reporter (you need something hybed to a probe on the array to get an intensity) and maybe a more general term for 'measuring intensities'. We need to find the right balance between what is consistent with OBI and combinations of its terms and what is user-friendly. Finally, note that 'intensity' is already in the OBI .owl file and is also in PATO. Why didn't OBI import it from PATO? This might be a problem.",,A measurement datum that represents the output of a scanner measuring the intensity value for each fluorescent reporter.,group:OBI,,,,,,fluorescent reporter intensity,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000010,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,fluorescent reporter intensity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0200006,biexponential transformation,,"A biexponential transformation is a data transformation that, for each (one dimensional) real number input x, outputs an approximation (found, e.g. with the Newton's method) to a solution y of the equation B(y)-x=0, where B denotes a b transformation.",false,,,http://purl.obolibrary.org/obo/OBI_0200169|http://purl.obolibrary.org/obo/OBI_0200072,,http://purl.obolibrary.org/obo/OBI_0200174,,,,,,,,,,,,,,,,,"A biexponential transformation is a data transformation that, for each (one dimensional) real number input x, outputs an approximation (found, e.g. with the Newton's method) to a solution y of the equation B(y)-x=0, where B denotes a b transformation.",WEB: http://flowcyt.sourceforge.net/gating/latest.pdf,,,,,,biexponential transformation,,This type of transformation is typically used in flow cytometry.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200006,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,biexponential transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Ryan Brinkman|Joseph Spliden|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/IAO_0000093,obsolete2_binary executable,,"Binary executable is a digital entity consisting of the binary representation of machine instructions of a specific processor or they may be binary pseudocode for a virtual machine. A non-source executable file is also called an object program. It is assumed that the binary executable file contains properly-formatted computer instructions.  (derived from Wikipedia, Nov 1, 2007)",true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,"Binary executable is a digital entity consisting of the binary representation of machine instructions of a specific processor or they may be binary pseudocode for a virtual machine. A non-source executable file is also called an object program. It is assumed that the binary executable file contains properly-formatted computer instructions.  (derived from Wikipedia, Nov 1, 2007)",group:OBI|OBI_0000222,,,,,"3/22/2009 Alan Ruttenberg, obsoleted per http://groups.google.com/group/information-ontology/browse_thread/thread/789ad4b7708d5cf4
superclass was 'digital entity'",obsolete2_binary executable,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,IAO:0000093,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete2_binary executable,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0001818,epitope specific chemokine (C-X-C motif) ligand 12 production by T cells,,A process of chemokine (C-X-C motif) ligand 12 production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0097390|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,Date: 2012-11-16; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mappings: MMExpressionsTcell.txt,,A process of chemokine (C-X-C motif) ligand 12 production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific chemokine (C-X-C motif) ligand 12 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001818,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific chemokine (C-X-C motif) ligand 12 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/CHEBI_32142,sodium citrate dihydrate,,The dihydrate of trisodium citrate.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,The dihydrate of trisodium citrate.,,,,,,,sodium citrate dihydrate,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:32142,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,sodium citrate dihydrate,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001052,two-photon laser/detector,,"A light source used in fluorescence imaging that allows the imaging of living tissue up to a depth of 1 mm, based on the concept that two photons of low energy can excite a fluorophore in a quantum event, resulting in the emission of a fluorescence photon, typically at a higher energy than either of the two excitatory photons.",false,,,http://purl.obolibrary.org/obo/OBI_0400065,,,,,,,,,,,,,,,,,,,"A light source used in fluorescence imaging that allows the imaging of living tissue up to a depth of 1 mm, based on the concept that two photons of low energy can excite a fluorophore in a quantum event, resulting in the emission of a fluorescence photon, typically at a higher energy than either of the two excitatory photons.",http://en.wikipedia.org/wiki/Two-photon_excitation_microscopy,,,,,,two-photon laser/detector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001052,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,two-photon laser/detector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001591,direct binding assay,,a binding assay that measures the formation or disassociation of a complex of 2 material entities directly without use of a competitve ligand. ,false,,,http://purl.obolibrary.org/obo/OBI_0001146,,,,,,,,,,,,,,,,,,,a binding assay that measures the formation or disassociation of a complex of 2 material entities directly without use of a competitve ligand. ,IEDB,,,,,,direct binding assay,,"Detecting the binding of a fluorescently labeled antibody to a peptide bound to the bottom of an ELISA plate, by incubating the antibody in the well, washing the plate, and detecing fluorescence which is a proxy for the presence of the bound antibody. 
",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001591,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,direct binding assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Bjoern Peters, Randi Vita",,
http://purl.obolibrary.org/obo/OBI_0001872,sequence assembly process,,"A data transformation that assembles two or more individual sequence reads into contiguous sequences (i.e., contigs).",false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,"A data transformation that assembles two or more individual sequence reads into contiguous sequences (i.e., contigs).",NIAID GSCID-BRC metadata working group,,,,,"PRS/AGB:
changed to restrictions by adding 2 possible specified outputs (N50 and genome coverage) for sequence assembly.
",sequence assembly process,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000973,http://purl.obolibrary.org/obo/OBI_0001939|http://purl.obolibrary.org/obo/OBI_0001940|http://purl.obolibrary.org/obo/OBI_0000973,,,OBI:0001872,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sequence assembly process,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Jie Zheng, Chris Stoeckert|Alejandra Gonzalez-Beltran|Philippe Rocca-Serra",,
http://purl.obolibrary.org/obo/OBI_0000389,isoelectric focusing device,isoelectric focusing unit,An isoelectric focusing device is a device in which isoelectric focusing can be performed. An isoelectric focussing device had the function to contain and control the contained environment and transfer electrical energy from a power supply to a separation medium and the charged material to be separated.,false,,,http://purl.obolibrary.org/obo/OBI_0000967|http://purl.obolibrary.org/obo/OBI_0001034,,,,isoelectric focusing unit,,http://purl.obolibrary.org/obo/OBI_0000654,,,,,,,,,,,,,An isoelectric focusing device is a device in which isoelectric focusing can be performed. An isoelectric focussing device had the function to contain and control the contained environment and transfer electrical energy from a power supply to a separation medium and the charged material to be separated.,sep:00097,,,,,,isoelectric focusing device,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000370|http://purl.obolibrary.org/obo/OBI_0000383|http://purl.obolibrary.org/obo/OBI_0000401,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000389,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,isoelectric focusing device,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Frank Gibson,,
http://purl.obolibrary.org/obo/OBI_0001411,cell type comparison design,,"A study design that compares cells of different type, for example different cell lines.",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A study design that compares cells of different type, for example different cell lines.",MO_764 cell_type_comparison_design,,,,,,cell type comparison design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000219,,,,,,,,,,,,,,,,OBI:0001411,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cell type comparison design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0302732,solvent role,,solvent role is a role which inheres in a molecular entity capable of ensuring the dissolution of another chemical entity and realized by the process of solvation,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,,,solvent role is a role which inheres in a molecular entity capable of ensuring the dissolution of another chemical entity and realized by the process of solvation,adpated from wikipedia (http://en.wikipedia.org/wiki/Solvatation),,,,,,solvent role,,PMID: 18373502.Transfusion. 2008 Mar 25. Solvent/detergent treatment of platelet concentrates enhances the release of growth factors.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302732,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,solvent role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000296,obsolete_enrollment,,enrollment is a process of identifying a set of objects for further use in an investigation based on a set of criteria or rules,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,enrollment is a process of identifying a set of objects for further use in an investigation based on a set of criteria or rules,IEDB,,,,,merged with 'enrollment of human subjects,obsolete_enrollment,,"Enrollment of patients in a study.
Short-term outcome of neuropsychiatric events in systemic lupus erythematosus upon enrollment into an international inception cohort study. Arthritis Rheum. 2008 May 15;59(5):721-9. PMID: 18438902",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000227,,,,,,,,,,,,,,,,,,OBI:0000296,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_enrollment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_1110001,epitope,,a material entity bearing the epitope role,false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,a material entity bearing the epitope role,IEDB,,,,,,epitope,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110001,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000540,isolation of adherent cells,,a material separation process in which cells that stick to the container in which they are grown as a cell culture are separated from those in the liquid component of the culture. The output of this process are adherent cells.,false,,,http://purl.obolibrary.org/obo/OBI_0000512,,,,,,,,,,,,,,,,,,,a material separation process in which cells that stick to the container in which they are grown as a cell culture are separated from those in the liquid component of the culture. The output of this process are adherent cells.,,,,,,,isolation of adherent cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100060,http://purl.obolibrary.org/obo/OBI_0100060,,,OBI:0000540,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,isolation of adherent cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000735,NTP-2000,,"a material consisting of 14.5% protein, 8.5% fat and 9.5% fiber produced to feed rodents",false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,,,,,,,,,,,,,,,,"a material consisting of 14.5% protein, 8.5% fat and 9.5% fiber produced to feed rodents",,,,,,,NTP-2000,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000248,,,,,,,,,,,,OBI:0000735,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000457,,,NTP-2000,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Jennifer Fostel, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0400112,liquid handler,liquid_handling_instrument,a device that is used for automated liquid transfer and handling.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,liquid_handling_instrument,,,,,,,,,,,,,"DS: Is this class justified? Its a unnamed class. If so, put a fluidic_system and the fluidic_subsystem as subclasses.
TW: This is required by MO.
FG & DS: Capture as function.
All: Needs to be reviewed, according to query use case. If we keep it its kept as unnamed owl class.
The liquid handling class remains but as an undefined class with are unlikely to have children. It is expected that the reasoner would classifiy appropriate classes under this class that meet the have the liquid_handling function relation.|DS: Is this class justified? Its a unnamed class. If so, put a fluidic_system and the fluidic_subsystem as subclasses.
TW: This is required by MO.
FG: Or as function.",,a device that is used for automated liquid transfer and handling.,MO_868 liquid_handler,,,,,,liquid handler,,Beckman BioMek 2000,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000383,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400112,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,liquid handler,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000339,planning,,a process of creating or modifying a plan specification,false,,,http://purl.obolibrary.org/obo/BFO_0000015,,,,,,,,,,,,,,,,,,,a process of creating or modifying a plan specification,Bjoern Peters|Plans and Planned Processes Branch,,,,,"7/18/2011 BP: planning used to itself be a planned process. Barry Smith pointed out that this would lead to an infinite regression, as there would have to be a plan to conduct a planning process, which in itself would be the result of planning etc. Therefore, the restrictions on 'planning' were loosened to allow for informal processes that result in an 'ad hoc plan '. This required changing from 'has_specified_output some plan specifiction' to 'has_participant some plan specification'. ",planning,,"The process of a scientist thinking about and deciding what reagents to use as part of a protocol for an experiment. Note that the scientist could be human or a ""robot scientist"" executing software.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000339,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,planning,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000113,sequence feature identification objective,,"Sequence_feature_identification_objective is a biological_feature_identification_objective role describing a study designed to examine or characterize molecular features exhibited at the level of a macromolecular sequence, e.g. nucleic acid, protein, polysaccharide.",false,,,http://purl.obolibrary.org/obo/OBI_0000015,,,,,,,,,,,,,,,,,,,"Sequence_feature_identification_objective is a biological_feature_identification_objective role describing a study designed to examine or characterize molecular features exhibited at the level of a macromolecular sequence, e.g. nucleic acid, protein, polysaccharide.",,,,,,,sequence feature identification objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000113,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sequence feature identification objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_1110179,MHC tetramer/multimer assay measuring binding of a T cell epitope:MHC:TCR complex,qualitative binding|multimer/tetramer,A T cell epitope qualitative binding assay that uses an MHC multimer staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001317|http://purl.obolibrary.org/obo/OBI_1110124,,,,,,,,,,,,,,,,,,,A T cell epitope qualitative binding assay that uses an MHC multimer staining assay.,IEDB,,,,,,MHC tetramer/multimer assay measuring binding of a T cell epitope:MHC:TCR complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110179,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|multimer/tetramer,,,,,,,,,,,,,,,,,,,,,,MHC tetramer/multimer assay measuring binding of a T cell epitope:MHC:TCR complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000546,capillary pump system,,A pump system optimized for capillary chromatography.,false,,,http://purl.obolibrary.org/obo/OBI_0000589,,,,,,,,,,,,,,,,,,,A pump system optimized for capillary chromatography.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01051,,,,,,capillary pump system,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000546,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,capillary pump system,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000693,MeDIP-seq assay,Methylated DNA immunoprecipitation sequencing assay,"is an assay which aims at identifying methylated sites in genomic DNA and determining methylation pattern that affect  gene transcription by relying on immunoprecipitation of methylated genomic DNA, creation of a library of corresponding DNA fragments (either single or paired-end fragments) and subsequent sequencing using parallelized sequencing methods.",false,,,http://purl.obolibrary.org/obo/OBI_0000634|http://purl.obolibrary.org/obo/OBI_0600047|http://purl.obolibrary.org/obo/OBI_0001956,,http://purl.obolibrary.org/obo/OBI_0000441,,Methylated DNA immunoprecipitation sequencing assay,,,,,,,,,,,,,,,"is an assay which aims at identifying methylated sites in genomic DNA and determining methylation pattern that affect  gene transcription by relying on immunoprecipitation of methylated genomic DNA, creation of a library of corresponding DNA fragments (either single or paired-end fragments) and subsequent sequencing using parallelized sequencing methods.",adapted from wikipedia,,,,,,MeDIP-seq assay,,"PMID: 18612301. A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis. Down TA, Rakyan VK, Turner DJ, Flicek P, Li H, Kulesha E, Gräf S, Johnson N, Herrero J, Tomazou EM, Thorne NP, Bäckdahl L, Herberth M, Howe KL, Jackson DK, Miretti MM, Marioni JC, Birney E, Hubbard TJ, Durbin R, Tavaré S, Beck S. Nat Biotechnol. 2008 Jul;26(7):779-85.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000690|http://purl.obolibrary.org/obo/OBI_0000711,,,,,,,,,,,,,,,,OBI:0000693,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,MeDIP-seq assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000969,dose specification,,a directive information entity that describes the dose that will be administered to a target,false,,,http://purl.obolibrary.org/obo/IAO_0000033,,,,,,,,,,,,,,,,,,,a directive information entity that describes the dose that will be administered to a target,,,,,,,dose specification,,a protocol specifying to administer 1 ml of vaccine to a mouse,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000969,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,dose specification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://www.geneontology.org/formats/oboInOwl#Subset,Subset,,,false,,,http://purl.obolibrary.org/obo/IAO_0000102,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,oboInOwl:Subset,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001233,biological activity assay measuring epitope specific granulocyte macrophage colony stimulating factor production by T cells,GM-CSF release|biological activity,A T cell epitope specific cytokine production assay that detects granulocyte macrophage colony stimulating factor production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects granulocyte macrophage colony stimulating factor production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific granulocyte macrophage colony stimulating factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001233,,,,,,,,,,,,,,,,,,,,,,,,GM-CSF release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific granulocyte macrophage colony stimulating factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_1110111,environmental proximity to infectious agent,,Is a process in which an infectious agent comes close enough to a potential host organism in its habitat that a contact can result,false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,Is a process in which an infectious agent comes close enough to a potential host organism in its habitat that a contact can result,IEDB,,,,,,environmental proximity to infectious agent,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110111,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,environmental proximity to infectious agent,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001578,ELISA measuring epitope specific vascular endothelial growth factor production by T cells,VEGF release|ELISA,An assay of epitope specific vascular endothelial growth factor production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001570,,,,,,,,,,,,,,,,,,,An assay of epitope specific vascular endothelial growth factor production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific vascular endothelial growth factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001578,,,,,,,,,,,,,,,,,,,,,,,,VEGF release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific vascular endothelial growth factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000960,reagent application function,,A function that is realized when a reagent is automatically added to some research material.,false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,"4/10/2011: It is unclear if we need / want this, or what this is supposed to be for. Lots of the functions we have are reagent specific. Will this only confuse people?",,A function that is realized when a reagent is automatically added to some research material.,"PERSON: Nicole Vasilevsky, Matthew Brush",,,,,,reagent application function,,An automatic tissue processor automatically applies antibodies and buffers to histological tissue preparations.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000960,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,reagent application function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Nicole Vasilevsky, Matthew Brush",,
http://purl.obolibrary.org/obo/OBI_0200095,exponential transformation,,"An exponential transformation is a data transformation consisting in the application of the exponential function with a given base a (where a>0 and a is typically not equal to 1) to a (one dimensional) real number input. For alternative definitions and properties of this function see, e.g., http://en.wikipedia.org/wiki/Exponential_function and http://en.wikipedia.org/wiki/Characterizations_of_the_exponential_function.",false,,,http://purl.obolibrary.org/obo/OBI_0200169,,http://purl.obolibrary.org/obo/OBI_0200167,,,,,,,,,,,,,,,,,"An exponential transformation is a data transformation consisting in the application of the exponential function with a given base a (where a>0 and a is typically not equal to 1) to a (one dimensional) real number input. For alternative definitions and properties of this function see, e.g., http://en.wikipedia.org/wiki/Exponential_function and http://en.wikipedia.org/wiki/Characterizations_of_the_exponential_function.",WEB: http://en.wikipedia.org/wiki/Exponential_function|WEB: http://en.wikipedia.org/wiki/Characterizations_of_the_exponential_function,,,,,,exponential transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200095,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,exponential transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/CHEBI_31643,gadoteridol,,A non-ionic gadolinium chelate having a macrocyclic tetraamine framework. It is used as a paramagnetic contrast agent in magnetic resonance imaging (MRI).,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,A non-ionic gadolinium chelate having a macrocyclic tetraamine framework. It is used as a paramagnetic contrast agent in magnetic resonance imaging (MRI).,,,,,,,gadoteridol,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:31643,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,gadoteridol,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001319,cell culture analyte detection bioassay measuring epitope specific interferon-gamma production by T cells,IFNg release|bioassay,An assay of epitope specific interferon-gamma production by T cells that uses a cell culture analyte detection bioassay.,false,,,http://purl.obolibrary.org/obo/OBI_0001414,,,,,,,,,,,,,,,,,,,An assay of epitope specific interferon-gamma production by T cells that uses a cell culture analyte detection bioassay.,IEDB,,,,,,cell culture analyte detection bioassay measuring epitope specific interferon-gamma production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001319,,,,,,,,,,,,,,,,,,,,,,,,IFNg release|bioassay,,,,,,,,,,,,,,,,,,,,,,cell culture analyte detection bioassay measuring epitope specific interferon-gamma production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_1110203,epitope specific IL-6 release by T cells,,A biological process where T cells produce IL-6 resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/OBI_0001193|http://purl.obolibrary.org/obo/GO_0032635,,,,,,,,,,,,,,,,,,,A biological process where T cells produce IL-6 resulting from the recognition of a T cell epitope.,IEDB,,,,,,epitope specific IL-6 release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110203,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific IL-6 release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_1110126,assay measuring binding of a MHC:ligand complex,MHC binding|binding assay,A MHC ligand assay that detects the binding of a ligand to an MHC molecule.,false,,,http://purl.obolibrary.org/obo/OBI_0002075,,,,,,,,,,,,,,,,,,,A MHC ligand assay that detects the binding of a ligand to an MHC molecule.,IEDB,,,,,,assay measuring binding of a MHC:ligand complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110126,,,,,,,,,,,,,,,,,,,,,,,,MHC binding|binding assay,,,,,,,,,,,,,,,,,,,,,,assay measuring binding of a MHC:ligand complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/PATO_0001347,F mating type,,A bacterial mating type indicating the presence of F plasmid in a bacterial cell.,false,,,http://purl.obolibrary.org/obo/PATO_0000047,,,,,,,,,,,,,,,,,,,A bacterial mating type indicating the presence of F plasmid in a bacterial cell.,,,,,,,F mating type,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001347,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,F mating type,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0001348,F minus mating type,,A bacterial mating type indicating the absence of F plasmid in a bacterial cell.,false,,,http://purl.obolibrary.org/obo/PATO_0000047,,,,,,,,,,,,,,,,,,,A bacterial mating type indicating the absence of F plasmid in a bacterial cell.,,,,,,,F minus mating type,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001348,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,F minus mating type,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0001346,h plus,,A S. pombe mating type determined by the mat1-Pc and mat1-Pi on the mat1 locus.,false,,,http://purl.obolibrary.org/obo/PATO_0000047,,,,,,,,,,,,,,,,,,,A S. pombe mating type determined by the mat1-Pc and mat1-Pi on the mat1 locus.,,,,,,,h plus,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001346,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,h plus,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0001341,a mating type (yeast),,A S. cerevisiae mating type cells that secrete a pheromone that in alpha haploids stimulates processes that lead to mating.,false,,,http://purl.obolibrary.org/obo/PATO_0000047,,,,,,,,,,,,,,,,,,,A S. cerevisiae mating type cells that secrete a pheromone that in alpha haploids stimulates processes that lead to mating.,,,,,,,a mating type (yeast),,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001341,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,a mating type (yeast),,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0001340,hermaphrodite,,A biological sex quality inhering in an organism or a population with both male and female sexual organs in one individual.,false,,,http://purl.obolibrary.org/obo/PATO_0000047,,,,,,,,,,,,,,,,,,,A biological sex quality inhering in an organism or a population with both male and female sexual organs in one individual.,,,,,,,hermaphrodite,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001340,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,hermaphrodite,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0001345,h minus,,A S. pombe mating type determined by the mat1-Mc and mat1-Mi on the mat1 locus.,false,,,http://purl.obolibrary.org/obo/PATO_0000047,,,,,,,,,,,,,,,,,,,A S. pombe mating type determined by the mat1-Mc and mat1-Mi on the mat1 locus.,,,,,,,h minus,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001345,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,h minus,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0001344,alpha mating type (yeast),,A S. cerevisiae mating type cells that secrete a pheromone that stimulates a haploids.,false,,,http://purl.obolibrary.org/obo/PATO_0000047,,,,,,,,,,,,,,,,,,,A S. cerevisiae mating type cells that secrete a pheromone that stimulates a haploids.,,,,,,,alpha mating type (yeast),,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001344,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,alpha mating type (yeast),,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001391,biological activity assay measuring epitope specific interleukin-12 production by T cells,IL-12 release|biological activity,A T cell epitope specific cytokine production assay that detects interleukin-12 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects interleukin-12 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific interleukin-12 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001391,,,,,,,,,,,,,,,,,,,,,,,,IL-12 release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific interleukin-12 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000632,Bruker Metabolic Profiler,,"An NMR platform for conducting metabonomics studies, traditional metabolism studies, and analysis of complex mixtures, featuring an Avance NMR spectrometer and a microTOF from Bruker Daltonics. By combining the structural resolving power of NMR with mass accuracy of the microTOF Bruker offers a complete system for metabolic research. The Metabolic Profiler provides a simple, easy to use and inexpensive base-system to acquire the spectroscopic data, needed to do basic metabolic profiling including metabonomic statistical analysis.",false,,,http://purl.obolibrary.org/obo/OBI_0000596,,,,,,,,,,,,,,,,,NMR instrument|hyphenated NMR instrument platform,,"An NMR platform for conducting metabonomics studies, traditional metabolism studies, and analysis of complex mixtures, featuring an Avance NMR spectrometer and a microTOF from Bruker Daltonics. By combining the structural resolving power of NMR with mass accuracy of the microTOF Bruker offers a complete system for metabolic research. The Metabolic Profiler provides a simple, easy to use and inexpensive base-system to acquire the spectroscopic data, needed to do basic metabolic profiling including metabonomic statistical analysis.",WEB:<http://www.bruker-biospin.com/metabolicprofiler.html>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400199,,,,,,Bruker Metabolic Profiler,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000632,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker Metabolic Profiler,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001237,biological activity assay measuring epitope specific interleukin-21 production by T cells,IL-21 release|biological activity,A T cell epitope specific cytokine production assay that detects interleukin-21 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects interleukin-21 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific interleukin-21 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001237,,,,,,,,,,,,,,,,,,,,,,,,IL-21 release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific interleukin-21 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/IAO_0000578,centrally registered identifier,CRID,An information content entity that consists of a CRID symbol and additional information about the CRID registry to which it belongs.,false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,CRID,,,,,,,,,,,,,,,An information content entity that consists of a CRID symbol and additional information about the CRID registry to which it belongs.,"Original proposal from Bjoern, discussions at IAO calls",,,,,"2014-05-05: In defining this term we take no position on what the CRID denotes. In particular do not assume it denotes a *record* in the CRID registry (since the registry might not have 'records').|Note, IAO call 20101124: URIs are not always CRID, as not centrally registered. We acknowledge that CRID is a subset of a larger identifier class, but this subset fulfills our current needs. OBI PURLs are CRID as they are registered with OCLC. UPCs (Universal Product Codes from AC Nielsen)are not CRID as they are not centrally registered.|Alan, IAO call 20101124: potentially the CRID denotes the instance it was associated with during creation. 
",centrally registered identifier,,"The sentence ""The article has Pubmed ID 12345."" contains a CRID that has two parts: one part is the CRID symbol, which is '12345'; the other part denotes the CRID registry, which is Pubmed.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000577,,,,,,,,,,,,,,,,IAO:0000578,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,centrally registered identifier,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters|PERSON: Melanie Courtot|PERSON: Bill Hogan|PERSON: Alan Ruttenberg,,
http://purl.obolibrary.org/obo/UO_0000051,concentration unit,,A unit which represents a standard measurement of how much of a given substance there is mixed with another substance.,false,,,http://purl.obolibrary.org/obo/IAO_0000003,,,,,,,,,,,,,,,,,,,A unit which represents a standard measurement of how much of a given substance there is mixed with another substance.,,,,,,,concentration unit,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UO:0000051,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uo.owl,,,,,,,,,,,,,,,,,,,concentration unit,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001160,assay validation objective,,an objective specification to check the accuracy or the quality of the results of an assay by comparison with independent results,false,,,http://purl.obolibrary.org/obo/IAO_0000005,,,,,,,,,,,,,,,,,,,an objective specification to check the accuracy or the quality of the results of an assay by comparison with independent results,GROUP: Penn Group,,,,,,assay validation objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001160,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,assay validation objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000340,obsolete_documenting,,,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,,wikipedia http://en.wikipedia.org/wiki/Documenting,,,,,"6/11/9: Edited at workshop. Should go into IAO. We need to be able identify a child form of information artifact which corresponds to something enduring (not brain like). This used to be restricted to physical document or digital entity as the output, but that excludes e.g. an audio cassette tape",obsolete_documenting,,Recording the current temperature in a laboratory notebook. Writing a journal article. Updating a patient record in a database.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000228,,,,,,,,,,,,,,,,,,OBI:0000340,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_documenting,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,IAO_0000572,
http://purl.obolibrary.org/obo/OBI_0001446,epitope specific interleukin-15 production by T cells,,A process of interleukin-15 production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/OBI_0001193|http://purl.obolibrary.org/obo/GO_0032618,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of interleukin-15 production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific interleukin-15 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001446,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific interleukin-15 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001652,immuno staining assay measuring binding of a B cell epitope:antibody complex,qualitative binding|immuno staining,A B cell epitope qualitative binding to antibody assay that uses an immuno staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001703,,,,,,,,,,,,,,,,,,,A B cell epitope qualitative binding to antibody assay that uses an immuno staining assay.,IEDB,,,,,,immuno staining assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001652,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|immuno staining,,,,,,,,,,,,,,,,,,,,,,immuno staining assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0200192,classified data visualization,,A data visualization which has input of a classified data set and produces an output of a report graph which is capable of rendering data of this type.,false,,,http://purl.obolibrary.org/obo/OBI_0200111,,,,,,,,,,,,,,,,,,,A data visualization which has input of a classified data set and produces an output of a report graph which is capable of rendering data of this type.,,,,,,,classified data visualization,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200192,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,classified data visualization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0000911,real time reverse-transcription polymerase chain reaction  assay,RRT-PCR|RT-rt PCR|qRT-PCR,Is_a PCR real time preceded by a reverse transcription step (reverse transcription step = an RNA strand is reverse transcribed into its DNA complement using the enzyme reverse transcriptase),false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,RRT-PCR|RT-rt PCR|qRT-PCR,,,,,,,,,,,,,,,Is_a PCR real time preceded by a reverse transcription step (reverse transcription step = an RNA strand is reverse transcribed into its DNA complement using the enzyme reverse transcriptase),,,,,,,real time reverse-transcription polymerase chain reaction  assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000911,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,real time reverse-transcription polymerase chain reaction  assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot|PERSON: Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000547,evaporative light scattering detector,,"The evaporative light scattering detector, as its name implies, utilizes a spray that continuously atomizes the column eluent into small droplets. These droplets are allowed to evaporate, leaving the solutes as fine particulate matter suspended in the atomizing gas.",false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,"The evaporative light scattering detector, as its name implies, utilizes a spray that continuously atomizes the column eluent into small droplets. These droplets are allowed to evaporate, leaving the solutes as fine particulate matter suspended in the atomizing gas.",WEB:<http://www.chromatography-online.org/HPLC-Detectors/Evaporative-Light-Scattering/rs73.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01082,,,,,,evaporative light scattering detector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000547,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,evaporative light scattering detector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001761,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-X-C motif) ligand 16 production by T cells,CXCL16 release|RNA/DNA detection,An assay of epitope specific chemokine (C-X-C motif) ligand 16 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001778,,,,,,,,,,,,,,,,,,,An assay of epitope specific chemokine (C-X-C motif) ligand 16 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-X-C motif) ligand 16 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001761,,,,,,,,,,,,,,,,,,,,,,,,CXCL16 release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-X-C motif) ligand 16 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0600034,precipitation,,"a protocol application to cause a material to precipitate (becoming a solid) out of solution. Input is a solution, output is a solution plus a solid component (the precipitate)",false,,,http://purl.obolibrary.org/obo/OBI_0600014,,http://purl.obolibrary.org/obo/OBI_0000681,,,,,,,,,,,,,,,,,"a protocol application to cause a material to precipitate (becoming a solid) out of solution. Input is a solution, output is a solution plus a solid component (the precipitate)",OBI branch derived,,,,,,precipitation,,The use of ethanol to precipitate DNA molecules from a solution containing DNA,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600034,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,precipitation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Kevin Clancy,,
http://purl.obolibrary.org/obo/OBI_0001929,mass value specification,,A value specification that specifies the mass of some thing.,false,,,http://purl.obolibrary.org/obo/OBI_0001931,,,,,,,,,,,,,,,,,,,A value specification that specifies the mass of some thing.,,,,,,,mass value specification,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001929,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,mass value specification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/PATO_0000125,,,,,,,PERSON:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000023,classified data set,data set with assigned class labels,A data set that is produced as the output of a class prediction data transformation and consists of a data set with assigned class labels.,false,,,http://purl.obolibrary.org/obo/IAO_0000100,,,,data set with assigned class labels,,,,,,,,,,,,,,,A data set that is produced as the output of a class prediction data transformation and consists of a data set with assigned class labels.,,,,,,,classified data set,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000023,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,classified data set,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: James Malone|PERSON: Monnie McGee,,
http://purl.obolibrary.org/obo/OBI_0002031,genotyping by SNP array,DNA sequence variation detection by snp array,"A genotyping by array assay that aims to detect variation in (mostly) genomic DNA of an organism, strain, etc relative to some reference sequence employing snp array technology. ",false,,,http://purl.obolibrary.org/obo/OBI_0001274,,,,DNA sequence variation detection by snp array,,,,,,,,,,,,,,,"A genotyping by array assay that aims to detect variation in (mostly) genomic DNA of an organism, strain, etc relative to some reference sequence employing snp array technology. ",PMID:20393561,,,,,Details see tracker: https://sourceforge.net/p/obi/obi-terms/720/,genotyping by SNP array,,PMID:20080586,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001204,,,,,,,,,,,,,,,OBI:0002031,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,genotyping by SNP array,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Saccharomyces Genome Database (SGD),,,,,,,,"Person:Janos Demeter, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000467,Bruker US 2 NMR magnet,,"An actively-shielded superconducting magnet from Bruker that combines Bruker BioSpin's advanced, proprietary UltraShield active shielding and UltraStabilized sub-cooling technologies. This shielded and stabilized (US2) magnet system delivers high sensitivity and spectral dispersion.",false,,,http://purl.obolibrary.org/obo/OBI_0000597,,,,,,,,,,,,,,,,,NMR instrument,,"An actively-shielded superconducting magnet from Bruker that combines Bruker BioSpin's advanced, proprietary UltraShield active shielding and UltraStabilized sub-cooling technologies. This shielded and stabilized (US2) magnet system delivers high sensitivity and spectral dispersion.",WEB:<http://www.bruker-biospin.com/nmr_magnets_950us2.html>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400189,,,,,,Bruker US 2 NMR magnet,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000467,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker US 2 NMR magnet,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001614,GenBank ID,GenBank Record ID,A CRID symbol uniquely indentifies the submitted GeneBank sequence record.,false,,,http://purl.obolibrary.org/obo/IAO_0000577,,,,,,,,,,,,,,,,,,,A CRID symbol uniquely indentifies the submitted GeneBank sequence record.,NIAID GSCID-BRC metadata working group,,,,,,GenBank ID,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001614,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GenBank ID,,,,,,GenBank Record ID,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/NCBITaxon_1206794,Ecdysozoa,,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_33213,,,,,,,,,,,,,,,,,,,,,,,,,,Ecdysozoa,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:1206794,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Ecdysozoa,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001833,ELISPOT assay measuring epitope specific interleukin-17A production by T cells,IL-17A release|ELISPOT,A T cell epitope specific interleukin-17A production assay that uses an ELISPOT.,false,,,http://purl.obolibrary.org/obo/OBI_0001773|http://purl.obolibrary.org/obo/OBI_0001354,,,,,,,,,,,,,,,,,,,A T cell epitope specific interleukin-17A production assay that uses an ELISPOT.,IEDB,,,,,,ELISPOT assay measuring epitope specific interleukin-17A production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001833,,,,,,,,,,,,,,,,,,,,,,,,IL-17A release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific interleukin-17A production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001839,intracellular cytokine staining assay measuring epitope specific interleukin-16 production by T cells,IL-16 release|ICS,An assay of epitope specific interleukin-16 production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001280,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-16 production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-16 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001839,,,,,,,,,,,,,,,,,,,,,,,,IL-16 release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-16 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0200077,gating,,"Gating is a property-based vector selection with the objective of partitioning a data vector set into vector subsets based on dimension values of individual vectors (events), in which vectors represent individual physical particles (often cells) of a sample and dimension values represent light intensity qualities as measured by flow cytometry.",false,,,http://purl.obolibrary.org/obo/OBI_0200171|http://purl.obolibrary.org/obo/OBI_0200182,,http://purl.obolibrary.org/obo/OBI_0200157|http://purl.obolibrary.org/obo/OBI_0200172,,,,,,,,,,,,,,,,,"Gating is a property-based vector selection with the objective of partitioning a data vector set into vector subsets based on dimension values of individual vectors (events), in which vectors represent individual physical particles (often cells) of a sample and dimension values represent light intensity qualities as measured by flow cytometry.",PERSON: James Malone|PERSON: Josef Spidlen|PERSON: Ryan Brinkman|PERSON: Richard Scheuermann|PERSON:Melanie Courtot,,,,,,gating,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200077,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,gating,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Josef Spidlen|James Malone|Ryan Brinkman|Melanie Courtot|Richard Scheuermann,,
http://purl.obolibrary.org/obo/OBI_0400023,CYFlow ML,,"A CyFlow_ML is a flow_cytometer_analyser manufactured by Partec. It is a digital machine which uses 4 light sources: triple laser configurations including new powerful 200mW@488nm blue solid state laser + 100W UV lamp for highest resolution DNA analysis, and can collect 16 optical parameters: FSC1, FSC2, SSC, FL1-FL13. Ultracompact high end desktop multilaser Flow Cytometer for all applications in cell analysis and absolute counting.",false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,,,,,,,,,,,,,,,,"A CyFlow_ML is a flow_cytometer_analyser manufactured by Partec. It is a digital machine which uses 4 light sources: triple laser configurations including new powerful 200mW@488nm blue solid state laser + 100W UV lamp for highest resolution DNA analysis, and can collect 16 optical parameters: FSC1, FSC2, SSC, FL1-FL13. Ultracompact high end desktop multilaser Flow Cytometer for all applications in cell analysis and absolute counting.",http://www.partec.de/products/cyflow-ml.html,,,,,,CYFlow ML,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400023,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CYFlow ML,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0001528,material service,,A service which has a material entity as specified input and/or specified output.,false,,,http://purl.obolibrary.org/obo/OBI_0001173,,,,,,,,,,,,,,,,,,,A service which has a material entity as specified input and/or specified output.,PERSON: Carlo Torniai,,,,,,material service,,"A service performing DNA sequencing, a service preforming cell analysis. A service performing cell line immortalization",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001528,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,material service,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Carlo Torniai|PERSON: Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_0000810,informed consent process,,A planned process in which a person or their legal representative is informed about key facts about potential risks and benefits of a process and makes a documented decision as to whether the person in question will participate.,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,,A planned process in which a person or their legal representative is informed about key facts about potential risks and benefits of a process and makes a documented decision as to whether the person in question will participate.,http://clinicaltrials.gov/ct2/info/glossary#informed,,,,,09/28/2009 Alan Ruttenberg: This is made a subclass of the higher level processual entity in BFO because I don't want to take a stand on whether it is a process aggregate. Analogous to the situation with Material entity.,informed consent process,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/NCBITaxon_9606,,,,OBI:0000810,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,informed consent process,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0000641,JEOL ECA NMR spectrometer,,"The ECA series of NMR spectrometers is a high performance, research grade NMR system configurable to a wide range off applications. The ECA NMR is available from 300 to 930 MHz field strengths and is 1GHz ready. The system is designed around a modular, digital NMR electronics chassis controlled from a UNIX or Windows workstation and acquisition system. Both the workstation and spectrometer may be connected to a standard network, allowing seamless remote operation anywhere in the world.",false,,,http://purl.obolibrary.org/obo/OBI_0000600,,,,,,,,,,,,,,,,,NMR instrument,,"The ECA series of NMR spectrometers is a high performance, research grade NMR system configurable to a wide range off applications. The ECA NMR is available from 300 to 930 MHz field strengths and is 1GHz ready. The system is designed around a modular, digital NMR electronics chassis controlled from a UNIX or Windows workstation and acquisition system. Both the workstation and spectrometer may be connected to a standard network, allowing seamless remote operation anywhere in the world.",WEB:<http://www.jeol.com/PRODUCTS/AnalyticalInstruments/NuclearMagneticResonance/ECA/tabid/146/Default.aspx>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400228,,,,,,JEOL ECA NMR spectrometer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000641,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,JEOL ECA NMR spectrometer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001469,monospecific T cell recognition assay measuring MHC ligand processing and presentation,ligand presentation|T cell recognition ,A MHC ligand processing and presentation assay in which the presence of a specific ligand in an eluate is detected using the response of T cells that are known to be monospecific for that ligand as a readout.,false,,,http://purl.obolibrary.org/obo/OBI_1110125,,,,,,,,,,,,,,,,,,,A MHC ligand processing and presentation assay in which the presence of a specific ligand in an eluate is detected using the response of T cells that are known to be monospecific for that ligand as a readout.,IEDB,,,,,,monospecific T cell recognition assay measuring MHC ligand processing and presentation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_1110037,,,,,,,,,,,,,,,,OBI:0001469,,,,,,,,,,,,,,,,,,,,,,,,ligand presentation|T cell recognition ,,,,,,,,,,,,,,,,,,,,,,monospecific T cell recognition assay measuring MHC ligand processing and presentation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001080,patch clamp device,,A device used in electrophysiology that allows the study of single or multiple ion channels in cells.,false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,A device used in electrophysiology that allows the study of single or multiple ion channels in cells.,http://en.wikipedia.org/wiki/Patch_clamp,,,,,,patch clamp device,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001080,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,patch clamp device,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/CHEBI_59424,bromophenol blue,,"3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 3,5-dibromo-4-hydroxyphenyl groups. It is used as a laboratory indicator, changing from yellow below pH 3 to purple at pH 4.6, and as a size marker for monitoring the progress of agarose gel and polyacrylamide gel electrophoresis. It has also been used as an industrial dye.",false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,"3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 3,5-dibromo-4-hydroxyphenyl groups. It is used as a laboratory indicator, changing from yellow below pH 3 to purple at pH 4.6, and as a size marker for monitoring the progress of agarose gel and polyacrylamide gel electrophoresis. It has also been used as an industrial dye.",,,,,,,bromophenol blue,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:59424,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,bromophenol blue,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000966,in live organism assay,in vivo assay,An assay in which a measurement is made by observing entities located in an organism.,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,in vivo assay,,,,,,,,,,,,,,,An assay in which a measurement is made by observing entities located in an organism.,,,,,,,in live organism assay,,Measuring the rate in which cells that are pulsed with a peptide are killed inside a mouse by peptide specific cytotoxic T cells.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000966,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,in live organism assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0500017,dye swap design,,"An experiment design type where the label orientations are reversed. exact synonym: flip dye, dye flip",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"An experiment design type where the label orientations are reversed. exact synonym: flip dye, dye flip",MO_858,,,,,,dye swap design,,"PMID: 17411393-Dye-specific bias effects, commonly observed in the two-color microarray platform, are normally corrected using the dye swap design. This design, however, is relatively expensive and labor-intensive. We propose a self-self hybridization design as an alternative to the dye swap design. In this design, the treated and control samples are labeled with Cy5 and Cy3 (or Cy3 and Cy5), respectively, without dye swap, along with a set of self-self hybridizations on the control sample. We compare this design with the dye swap design through investigation of mouse primary hepatocytes treated with three peroxisome proliferator-activated receptor-alpha (PPARalpha) agonists at three dose levels. Using Agilent's Whole Mouse Genome microarray, differentially expressed genes (DEG) were determined for both the self-self hybridization and dye swap designs. The DEG concordance between the two designs was over 80% across each dose treatment and chemical. Furthermore, 90% of DEG-associated biological pathways were in common between the designs, indicating that biological interpretations would be consistent. The reduced labor and expense for the self-self hybridization design make it an efficient substitute for the dye swap design. For example, in larger toxicogenomic studies, only about half the chips are required for the self-self hybridization design compared to that needed in the dye swap design.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500017,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,dye swap design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra on behalf of MO,,
http://purl.obolibrary.org/obo/OBI_0000398,image creation device,image acquisition device,An image creation device is a device which captures a digitized image of an object,false,,,http://purl.obolibrary.org/obo/OBI_0000832|http://purl.obolibrary.org/obo/OBI_0000968,,,,image acquisition device,,,,,,,,,,,,,,,An image creation device is a device which captures a digitized image of an object,sep:00096,,,,,,image creation device,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000398,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,image creation device,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Frank Gibson,,
http://purl.obolibrary.org/obo/NCBITaxon_2157,Archaea,,,false,,,http://purl.obolibrary.org/obo/OBI_0100026,,,,,,,,,,,,,,,,,,,,,,,,,,Archaea,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:2157,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Archaea,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001830,ELISPOT assay measuring epitope specific interleukin-17F production by T cells,IL-17F release|ELISPOT,A T cell epitope specific interleukin-17F production assay that uses an ELISPOT.,false,,,http://purl.obolibrary.org/obo/OBI_0001354|http://purl.obolibrary.org/obo/OBI_0001772,,,,,,,,,,,,,,,,,,,A T cell epitope specific interleukin-17F production assay that uses an ELISPOT.,IEDB,,,,,,ELISPOT assay measuring epitope specific interleukin-17F production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001830,,,,,,,,,,,,,,,,,,,,,,,,IL-17F release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific interleukin-17F production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/BFO_0000024,fiat object,,,false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,FiatObjectPart,fiat-object,,,,,,,,,,,,,,,,,BFO 2 Reference: Most examples of fiat object parts are associated with theoretically drawn divisions,fiat object,"b is a fiat object part = Def. b is a material entity which is such that for all times t, if b exists at t then there is some object c such that b proper continuant_part of  c at t and c is demarcated from the remainder of c by a two-dimensional continuant fiat boundary. (axiom label in BFO2 Reference: [027-004])","the upper and lower lobes of the left lung|the dorsal and ventral surfaces of the body|the division of the brain into regions|or with divisions drawn by cognitive subjects for practical reasons, such as the division of a cake (before slicing) into (what will become) slices (and thus member parts of an object aggregate). However, this does not mean that fiat object parts are dependent for their existence on divisions or delineations effected by cognitive subjects. If, for example, it is correct to conceive geological layers of the Earth as fiat object parts of the Earth, then even though these layers were first delineated in recent times, still existed long before such delineation and what holds of these layers (for example that the oldest layers are also the lowest layers) did not begin to hold because of our acts of delineation.Treatment of material entity in BFOExamples viewed by some as problematic cases for the trichotomy of fiat object part, object, and object aggregate include: a mussel on (and attached to) a rock, a slime mold, a pizza, a cloud, a galaxy, a railway train with engine and multiple carriages, a clonal stand of quaking aspen, a bacterial community (biofilm), a broken femur. Note that, as Aristotle already clearly recognized, such problematic cases – which lie at or near the penumbra of instances defined by the categories in question – need not invalidate these categories. The existence of grey objects does not prove that there are not objects which are black and objects which are white; the existence of mules does not prove that there are not objects which are donkeys and objects which are horses. It does, however, show that the examples in question need to be addressed carefully in order to show how they can be fitted into the proposed scheme, for example by recognizing additional subdivisions [29|the division of the planet into hemispheres|the Western hemisphere of the Earth|the FMA:regional parts of an intact human body.",,,,,,,,(forall (x) (if (FiatObjectPart x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y) (and (Object y) (properContinuantPartOfAt x y t)))))))) // axiom label in BFO2 CLIF: [027-004] ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000024,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,fiat object,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001626,Bioinformatics Resource Center,BRC,"An organization that  is one of the Internet-based research centers established and funded by NIAID (the National Institute of Allergy and Infectious Diseases). The Bioinformatics Resource Centers (BRCs) were formed in response to the threats posed by emerging and re-emerging pathogens, particularly CDC Category A, B, and C pathogens, and their potential use in bioterrorism. The intention of NIAID in funding these bioinformatics centers is to assist researchers involved in the experimental characterization of such pathogens and the formation of drugs, vaccines, or diagnostic tools to combat them.",false,,,http://purl.obolibrary.org/obo/OBI_0000245,,,,BRC,,,,,,,,,,,,,,,"An organization that  is one of the Internet-based research centers established and funded by NIAID (the National Institute of Allergy and Infectious Diseases). The Bioinformatics Resource Centers (BRCs) were formed in response to the threats posed by emerging and re-emerging pathogens, particularly CDC Category A, B, and C pathogens, and their potential use in bioterrorism. The intention of NIAID in funding these bioinformatics centers is to assist researchers involved in the experimental characterization of such pathogens and the formation of drugs, vaccines, or diagnostic tools to combat them.",Website: http://en.wikipedia.org/wiki/Bioinformatics_Resource_Centers,,,,,,Bioinformatics Resource Center,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001626,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bioinformatics Resource Center,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/BFO_0000148,zero-dimensional temporal region,temporal instant.,,false,,,http://purl.obolibrary.org/obo/BFO_0000008,,,,temporal instant.,,,ZeroDimensionalTemporalRegion,0d-t-region,,,,,,,,,,,,,,,,,,zero-dimensional temporal region,A zero-dimensional temporal region is a temporal region that is without extent. (axiom label in BFO2 Reference: [102-001]),the moment at which a finger is detached in an industrial accident|the moment at which a child is born|the moment of death.|a temporal region that is occupied by a process boundary|right now,,,,,,,,(forall (x) (if (ZeroDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [102-001] ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000148,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,zero-dimensional temporal region,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200028,quantile transformation,,"A quantile transformation is a data transformation that takes as input a collection of data sets, where each can be thought as an n-dimensional (real) vector, and which transforms each data set so that the resulting output data sets have equal quantiles.",false,,,http://purl.obolibrary.org/obo/OBI_0200169|http://purl.obolibrary.org/obo/OBI_0200181,,http://purl.obolibrary.org/obo/OBI_0200167,,,,,,,,,,,,,,,,,"A quantile transformation is a data transformation that takes as input a collection of data sets, where each can be thought as an n-dimensional (real) vector, and which transforms each data set so that the resulting output data sets have equal quantiles.",PERSON: Elisabetta Manduchi,,,,,,quantile transformation,,"This can be used for expression microarray assay normalization and it is referred to as ""quantile normalization"", according to the procedure described e.g. in PMID 12538238.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200028,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,quantile transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0001911,cell line culture,,"A cell culture comprised of cell line cells and the media in which they are being actively propagated or quiescently stored.|A cell line culture includes the cells in culture, as well as the media and all additives/reagents in which the cells are being grown or in which they are stored.",false,,,http://purl.obolibrary.org/obo/OBI_0001876,,,,,,,,,,,,,,,,,,,A cell culture comprised of cell line cells and the media in which they are being actively propagated or quiescently stored.,OBI-CLO Alignment Working Group (Spring 2013),,,,,,cell line culture,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CLO_0000001,,,,,,,,,,,,,,,,OBI:0001911,,,,,,,,,,,,,,,,,,"A cell line culture includes the cells in culture, as well as the media and all additives/reagents in which the cells are being grown or in which they are stored.",,,,,,,,,,,,,,,,,,,,,,,,,,,,cell line culture,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_0302733,solute role,,solute role is a role played by a chemical entity which is dissolved by another chemical entity (the solvent) when creating a solution,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,,,solute role is a role played by a chemical entity which is dissolved by another chemical entity (the solvent) when creating a solution,adapted from wikipedia (http://en.wikipedia.org/wiki/Solute),,,,,,solute role,,PMID: 18380397.Pharmazie. 2008 Feb;63(2):113-21.Deviations of drug solubility in water-cosolvent mixtures from the Jouyban-Acree model--effect of solute structure.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302733,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,solute role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000514,Bruker AMX series NMR instrument,,"A series of older Bruker NMR magnets, now out of production. The Bruker AMX500 has proven an extremely reliable workhorse, with excellent lineshape yielding superior water suppression even without gradients. The Oxford 11.7 Tesla 5.2 cm bore magnet rests on a TMC vibration damping table. Homogeneity is controlled by a BSN-18 and BSN-2 with 19 shim controls. In addition to the 5 mm triple resonance probe, the AMX is equipped with a 10mm broadband observe probe.",false,,,http://purl.obolibrary.org/obo/OBI_0000596,,,,,,,,,,,,,,,,,NMR instrument,,"A series of older Bruker NMR magnets, now out of production. The Bruker AMX500 has proven an extremely reliable workhorse, with excellent lineshape yielding superior water suppression even without gradients. The Oxford 11.7 Tesla 5.2 cm bore magnet rests on a TMC vibration damping table. Homogeneity is controlled by a BSN-18 and BSN-2 with 19 shim controls. In addition to the 5 mm triple resonance probe, the AMX is equipped with a 10mm broadband observe probe.",WEB:<http://www.tufts.edu/med/biochemistry/NMR/amx500.html>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400240,,,,,,Bruker AMX series NMR instrument,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000514,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker AMX series NMR instrument,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000364,ion detector,,"An ion detector is a device that measures and records
the charge induced or current produced when an ion passes by or hits a
surface. 

Example: In a scanning instrument the signal produced in the detector
during the course of the scan versus where the instrument is in the
scan (at what m/Q) will produce a mass spectrum, a record of ions as a
function of m/Q.",false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,"An ion detector is a device that measures and records
the charge induced or current produced when an ion passes by or hits a
surface. 

Example: In a scanning instrument the signal produced in the detector
during the course of the scan versus where the instrument is in the
scan (at what m/Q) will produce a mass spectrum, a record of ions as a
function of m/Q.",http://en.wikipedia.org/wiki/Mass_spectrometry#Detector,,,,,,ion detector,,The ion detector of the Voyager-DE(tm) STR Biospectrometry Workstation,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000364,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ion detector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Frank Gibson,,
http://purl.obolibrary.org/obo/OBI_0000739,Student's t-test,,Studen't t-test is a data transformation with the objective of a statistical hypothesis test in which the test statistic has a Student's t distribution if the null hypothesis is true. It is applied when the population is assumed to be normally distributed but the sample sizes are small enough that the statistic on which inference is based is not normally distributed because it relies on an uncertain estimate of standard deviation rather than on a precisely known value.,false,,,http://purl.obolibrary.org/obo/OBI_0000673,,http://purl.obolibrary.org/obo/OBI_0000675,,,,,,,,,,,,,,,,,Studen't t-test is a data transformation with the objective of a statistical hypothesis test in which the test statistic has a Student's t distribution if the null hypothesis is true. It is applied when the population is assumed to be normally distributed but the sample sizes are small enough that the statistic on which inference is based is not normally distributed because it relies on an uncertain estimate of standard deviation rather than on a precisely known value.,WEB: http://en.wikipedia.org/wiki/T-test,,,,,,Student's t-test,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000175,,,OBI:0000739,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Student's t-test,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0000341,histological sample preparation,,histological sample preparation is the preparation of an input tissue via slicing and labeling to make tissue microstructure of interest visible in a future histology assay,false,,,http://purl.obolibrary.org/obo/OBI_0000094|http://purl.obolibrary.org/obo/OBI_0000659,,http://purl.obolibrary.org/obo/OBI_0000684|http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,histological sample preparation is the preparation of an input tissue via slicing and labeling to make tissue microstructure of interest visible in a future histology assay,OBI branch derived,,,,,,histological sample preparation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0400168,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100066,,,,OBI:0000341,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,histological sample preparation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0002056,biological activity assay measuring epitope specific chemokine (C-C motif) ligand 17 production by T cells,CCL17/TARC release|biological activity,A T cell epitope specific cytokine production assay that detects production of chemokine (C-C motif) ligand 17 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects production of chemokine (C-C motif) ligand 17 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific chemokine (C-C motif) ligand 17 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002056,,,,,,,,,,,,,,,,,,,,,,,,CCL17/TARC release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific chemokine (C-C motif) ligand 17 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0002054,NMR assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex,dissociation constant KD|nuclear magnetic resonance (NMR)|nM,A B cell epitope equilibrium dissociation constant (KD) determination assay that uses a nuclear magnetic resonance assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001708,,,,,,,,,,,,,,,,,,,A B cell epitope equilibrium dissociation constant (KD) determination assay that uses a nuclear magnetic resonance assay.,IEDB,,,,,,NMR assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002054,,,,,,,,,,,,,,,,,,,,,,,,dissociation constant KD|nuclear magnetic resonance (NMR)|nM,,,,,,,,,,,,,,,,,,,,,,NMR assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000738,restriction enzyme based cloning,,"restriction enzyme based cloning is a recombinant vector cloning process that has as an input genetic material that was cleaved with restriction enzymes, and a cloning vector that was cleaved with complementary restriction enzymes. It uses ligase to chemically join the input genetic material and the cloning vector to create a recombinant vector.",false,,,http://purl.obolibrary.org/obo/OBI_0600064,,,,,,,,,,,,,,,,,,,"restriction enzyme based cloning is a recombinant vector cloning process that has as an input genetic material that was cleaved with restriction enzymes, and a cloning vector that was cleaved with complementary restriction enzymes. It uses ligase to chemically join the input genetic material and the cloning vector to create a recombinant vector.",,,,,,,restriction enzyme based cloning,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0302892,,,,,,,,,,,,,,,,OBI:0000738,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,restriction enzyme based cloning,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Kevin Clancy, Bjoern Peters",,
http://purl.obolibrary.org/obo/IAO_0000591,software method,,"A software method (also called subroutine, subprogram, procedure, method, function, or routine) is software designed to execute a specific task.",false,,,http://purl.obolibrary.org/obo/IAO_0000010,,,,,,,,,,,,,,,,,,,"A software method (also called subroutine, subprogram, procedure, method, function, or routine) is software designed to execute a specific task.",http://code.google.com/p/information-artifact-ontology/issues/detail?id=80,,,,,,software method,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000591,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,software method,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot|PERSON: Michel Dumontier,,
http://purl.obolibrary.org/obo/IAO_0000443,data item extraction from journal article,,"a planned process in which journal articles are read or processed and data items are extracted, typically for further analysis or indexing",false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,,,"a planned process in which journal articles are read or processed and data items are extracted, typically for further analysis or indexing",,,,,,,data item extraction from journal article,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000013,http://purl.obolibrary.org/obo/IAO_0000027,,,IAO:0000443,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,data item extraction from journal article,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0001487,B cell epitope specific immune intervention,,An epitope specific immune intervention in which the induced response targets a B cell epitope,false,,,http://purl.obolibrary.org/obo/OBI_0001192,,,,,,,,,,,,,,,,,,,An epitope specific immune intervention in which the induced response targets a B cell epitope,IEDB,,,,,,B cell epitope specific immune intervention,,Injecting a mouse with recombinant antibody targeting an anthrax epitope,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001487,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,B cell epitope specific immune intervention,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000086,reagent role,reagent,"A role inhering in a biological or chemical entity that is intended to be applied in a scientific technique to participate (or have molecular components that participate) in a chemical reaction that facilitates the generation of data about some entity distinct from the bearer, or the generation of some specified material output distinct from the bearer.|(copied from ReO)
Reagents are distinguished from instruments or devices that also participate in scientific techniques by the fact that reagents are chemical or biological in nature and necessarily participate in or have parts that participate in some chemical interaction or reaction during their intended participation in some technique.  By contrast, instruments do not participate in a chemical reaction/interaction during the technique.

Reagents are distinguished from study subjects/evaluants in that study subjects and evaluants are that about which conclusions are drawn and knowledge is sought in an investigation - while reagents, by definition, are not.  It should be noted, however, that reagent and study subject/evaluant roles can be borne by instances of the same type of material entity - but a given instance will realize only one of these roles in the execution of a given assay or technique. For example, taq polymerase can bear a reagent role or an evaluant role.  In a DNA sequencing assay aimed at generating sequence data about some plasmid, the reagent role of the taq polymerase is realized. In an assay to evaluate the quality of the taq polymerase itself, the evaluant/study subject role of the taq is realized, but not the reagent role since the taq is the subject about which data is generated.

In regard to the statement that reagents are 'distinct' from the specified outputs of a technique, note that a reagent may be incorporated into a material output of a technique, as long as the IDENTITY of this output is distinct from that of the bearer of the reagent role.  For example, dNTPs input into a PCR are reagents that become part of the material output of this technique, but this output has a new identity (ie that of a 'nucleic acid molecule') that is distinct from the identity of the dNTPs that comprise it.  Similarly, a biotin molecule input into a cell labeling technique are reagents that become part of the specified output, but the identity of the output is that of some modified cell specimen which shares identity with the input unmodified cell specimen, and not with the biotin label. Thus, we see that an important criteria of 'reagent-ness' is that it is a facilitator, and not the primary focus of an investigation or material processing technique (ie not the specified subject/evaluant about which knowledge is sought, or the specified output material of the technique).",false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,reagent,,,,,,,,,,,,,"Feb 10, 2009.  changes after discussion at OBI Consortium Workshop Feb 2-6, 2009.  accepted as core term.

May 28 2013. Updated definition taken from ReO based on discussions initiated in Philly 2011 workshop.  Former defnition described a narrower view of reagents in chemistry that restricts bearers of the role to be chemical entities (""a role played by a molecular entity used to produce a chemical reaction to detect, measure, or produce other substances"").  Updated definition allows for broader view of reagents in the domain of biomedical research to include larger materials that have parts that participate chemically in a molecular reaction or interaction.
",,"A role inhering in a biological or chemical entity that is intended to be applied in a scientific technique to participate (or have molecular components that participate) in a chemical reaction that facilitates the generation of data about some entity distinct from the bearer, or the generation of some specified material output distinct from the bearer.",PERSON:Matthew Brush,,,,,,reagent role,,"Buffer, dye, a catalyst, a solvating agent.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000086,,,,,,,,,,,,,,,,,,"(copied from ReO)
Reagents are distinguished from instruments or devices that also participate in scientific techniques by the fact that reagents are chemical or biological in nature and necessarily participate in or have parts that participate in some chemical interaction or reaction during their intended participation in some technique.  By contrast, instruments do not participate in a chemical reaction/interaction during the technique.

Reagents are distinguished from study subjects/evaluants in that study subjects and evaluants are that about which conclusions are drawn and knowledge is sought in an investigation - while reagents, by definition, are not.  It should be noted, however, that reagent and study subject/evaluant roles can be borne by instances of the same type of material entity - but a given instance will realize only one of these roles in the execution of a given assay or technique. For example, taq polymerase can bear a reagent role or an evaluant role.  In a DNA sequencing assay aimed at generating sequence data about some plasmid, the reagent role of the taq polymerase is realized. In an assay to evaluate the quality of the taq polymerase itself, the evaluant/study subject role of the taq is realized, but not the reagent role since the taq is the subject about which data is generated.

In regard to the statement that reagents are 'distinct' from the specified outputs of a technique, note that a reagent may be incorporated into a material output of a technique, as long as the IDENTITY of this output is distinct from that of the bearer of the reagent role.  For example, dNTPs input into a PCR are reagents that become part of the material output of this technique, but this output has a new identity (ie that of a 'nucleic acid molecule') that is distinct from the identity of the dNTPs that comprise it.  Similarly, a biotin molecule input into a cell labeling technique are reagents that become part of the specified output, but the identity of the output is that of some modified cell specimen which shares identity with the input unmodified cell specimen, and not with the biotin label. Thus, we see that an important criteria of 'reagent-ness' is that it is a facilitator, and not the primary focus of an investigation or material processing technique (ie not the specified subject/evaluant about which knowledge is sought, or the specified output material of the technique).",,,,,,,,,,,,,,,,,,,,,,,,,,,,reagent role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Matthew Brush,,
http://purl.obolibrary.org/obo/SO_0000276,miRNA,,"Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.",false,,,http://purl.obolibrary.org/obo/SO_0000001,,,,,,,,,,,,,,,,,,,"Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.",,,,,,,miRNA,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,SO:0000276,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/so.owl,,,,,,,,,,,,,,,,,,,miRNA,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000984,dose,,"A measurement datum that measures the quantity of something that may be administered to an organism or that an organism may be exposed to. Quantities of nutrients, drugs, vaccines and toxins are referred to as doses.",false,,,http://purl.obolibrary.org/obo/IAO_0000109,,,,,,,,,,,,,,,,,,,"A measurement datum that measures the quantity of something that may be administered to an organism or that an organism may be exposed to. Quantities of nutrients, drugs, vaccines and toxins are referred to as doses.",,,,,,,dose,,An organism has been injected 1ml of vaccine,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000984,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,dose,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0600041,concentrate,,a protocol application to create an output material with an increased density of a material of interest that is part of the input material by separating other parts of the input material,false,,,http://purl.obolibrary.org/obo/OBI_0600014,,http://purl.obolibrary.org/obo/OBI_0000681,,,,,,,,,,,,,,,,,a protocol application to create an output material with an increased density of a material of interest that is part of the input material by separating other parts of the input material,OBI branch derived,,,,,,concentrate,,Evaporation of the solution containing DNA to increase the concentration of the DNA molecules,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600041,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,concentrate,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Kevin Clancy,,
http://purl.obolibrary.org/obo/OBI_0000034,supernatant role,,supernatant role is a role which inheres in a material entity and is realized by a material separation process using gravitational force in which the material bearing the supernatant role is the liquid component of the output material.,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,,,supernatant role is a role which inheres in a material entity and is realized by a material separation process using gravitational force in which the material bearing the supernatant role is the liquid component of the output material.,OBI,,,,,,supernatant role,,"Precipitation is the formation of a solid in a solution during a chemical reaction. When the reaction occurs, the solid formed is called the precipitate, and the liquid remaining above the solid is called the supernate.  Wikipedia",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000034,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,supernatant role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP: Role branch,,
http://purl.obolibrary.org/obo/OBI_0000823,thrombin time assay,,"A  thrombin time assay is on in which after liberating the plasma from whole blood by centrifugation, bovine Thrombin is added to the sample of plasma. The clot is formed and is detected optically or mechanically by a coagulation instrument. The time between the addition of the thrombin and the clot formation is recorded as the thrombin clotting time",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,,"A  thrombin time assay is on in which after liberating the plasma from whole blood by centrifugation, bovine Thrombin is added to the sample of plasma. The clot is formed and is detected optically or mechanically by a coagulation instrument. The time between the addition of the thrombin and the clot formation is recorded as the thrombin clotting time",WEB:http://en.wikipedia.org/wiki/Thrombin_time@2009/10/06,,,,,2009/10/18 Alan Ruttenberg. This assay was added during the fucoidan use case exercise but still needs to be fleshed out. Only the AT-III assay has more carefully specified inputs and outputs,thrombin time assay,,PMID:19696660#The thrombin time was determined using thromboclotin assay kit.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000823,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,thrombin time assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0001678,epitope specific granzyme A production by T cells,,A process of granzyme A production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0035746,,,,,,,,,,,,,,,,,Date: 2011-6-24; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mappings: MMExpressionsTcell.txt,,A process of granzyme A production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific granzyme A production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001678,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific granzyme A production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000812,measuring neural activity in the caudate nucleus,,The process of measuring neural activity  in the caudate nucleus,false,,,http://purl.obolibrary.org/obo/OBI_0000454,,,,,,,,,,,,,,,,,,,The process of measuring neural activity  in the caudate nucleus,"Jessica Turner, NIF, Dirk Derom, OBI",,,,,,measuring neural activity in the caudate nucleus,,An SU micro-electrode was used to measure neural activity in the form of spike trains in the caudate nucleus of monkeys in response to a flashing light stimulus,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000812,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,measuring neural activity in the caudate nucleus,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/UBERON_0001873,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0000793,double blind study execution,,A double blind study execution is defined as any study execution in which neither the subjects nor the investigators are informed of which study arm the subjects are part of during the portion of the trial when the subjects are being treated,false,,,http://purl.obolibrary.org/obo/OBI_0000822|http://purl.obolibrary.org/obo/OBI_0000826,,,,,,,,,,,,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,,A double blind study execution is defined as any study execution in which neither the subjects nor the investigators are informed of which study arm the subjects are part of during the portion of the trial when the subjects are being treated,http://clinicaltrials.gov/ct2/info/glossary#double,,,,,,double blind study execution,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000793,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,double blind study execution,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0001514,minimal inhibitory concentration,,A scalar measurement datum that indicates the lowest concentration at which a specific compound significantly inhibits a process from occurring compared to in the absence of the compound.,false,,,http://purl.obolibrary.org/obo/IAO_0000032,,,,,,,,,,,,,,,,,,,A scalar measurement datum that indicates the lowest concentration at which a specific compound significantly inhibits a process from occurring compared to in the absence of the compound.,"Bjoern Peters, coordinated with Albert Goldfain",,,,,Created following request by Albert Goldfain,minimal inhibitory concentration,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,http://purl.obolibrary.org/obo/UO_0000051,,,,,,,,,,,,,,,,,,,,,OBI:0001514,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001172,,,,,,,,,,,,,,,,minimal inhibitory concentration,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000481,chromatography detector,,"A chromatography detector is a device that locates in the dimensions of space and time, the positions of the components of a mixture that has been subjected to a chromatographic process and thus permits the senses to appreciate the nature of the separation.  Defining characteristics are Dynamic Range, Response Index or Linearity, Linear Dynamic range, Detector Response,  Detector Noise Level, Detector Sensitivity or Minimum Detectable Concentration, Total System Dispersion, Sensor Dimensions, Detector Time Constant, Pressure Sensitivity, Flow Sensitivity, Operating Temperature Range.",false,,,http://purl.obolibrary.org/obo/OBI_0000485,,,,,,,,,,,,,,,,,,,"A chromatography detector is a device that locates in the dimensions of space and time, the positions of the components of a mixture that has been subjected to a chromatographic process and thus permits the senses to appreciate the nature of the separation.  Defining characteristics are Dynamic Range, Response Index or Linearity, Linear Dynamic range, Detector Response,  Detector Noise Level, Detector Sensitivity or Minimum Detectable Concentration, Total System Dispersion, Sensor Dimensions, Detector Time Constant, Pressure Sensitivity, Flow Sensitivity, Operating Temperature Range.",WEB:<http://www.chromatography-online.org/GC-Detectors/Classification/rs1.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01012,,,,,,chromatography detector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000481,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,chromatography detector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000401,environment control function,,"An environmental control function is a function that regulates a contained environment within specified parameter ranges. For example the control of light exposure, humidity and temperature.",false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,"An environmental control function is a function that regulates a contained environment within specified parameter ranges. For example the control of light exposure, humidity and temperature.",,,,,,,environment control function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000401,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,environment control function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bill Bug|Daniel Schober|Frank Gibson|Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0000435,genotyping assay,"genotype profiling, SNP genotyping|SNP analysis","an assay which generates data about a genotype from a specimen of genomic DNA. A variety of
techniques and instruments can be used to produce information about sequence variation at particular genomic positions.",false,,,http://purl.obolibrary.org/obo/OBI_0000443,,http://purl.obolibrary.org/obo/OBI_0000113,,"genotype profiling, SNP genotyping",,,,,,,,,,,,,,,"an assay which generates data about a genotype from a specimen of genomic DNA. A variety of
techniques and instruments can be used to produce information about sequence variation at particular genomic positions.",OBI Biomaterial,,,,,,genotyping assay,,High-throughput genotyping of oncogenic human papilloma viruses with MALDI-TOF mass spectrometry. Clin Chem. 2008 Jan;54(1):86-92. Epub 2007 Nov 2.PMID: 17981923,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001305,,,OBI:0000435,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,SNP analysis,genotyping assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/GO_0006338,chromatin remodeling,,Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.,false,,,http://purl.obolibrary.org/obo/GO_0009987,,,,,,,,,,,,,,,,,,,Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.,,,,,,,chromatin remodeling,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0006338,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,chromatin remodeling,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000483,APOLLO console,,"The APOLLO is a compact, modular, multiple-DSP, Windows XP Professional-based console that can be equipped with up to 8 DDS-based RF transmitter channels configurable from 2 kHz to 3.5 GHz. Each transmitter channel produces a nominal 1V output and has the most agile frequency, phase and amplitude control of any system on the market. An array of additional options are available including multiple RF transmitters, linear high-power RF amplifiers, digital receiver arrays, low noise figure preamplifiers, a gradient control system, shim unit, MAS spin-speed controller, variable temperature unit, digital lock system and probe/coil interface. With its numerous options, the Apollo can be configured for any NMR, NQR or MRI application.",false,,,http://purl.obolibrary.org/obo/OBI_0000599,,,,,,,,,,,,,,,,,NMR instrument/NMR console,,"The APOLLO is a compact, modular, multiple-DSP, Windows XP Professional-based console that can be equipped with up to 8 DDS-based RF transmitter channels configurable from 2 kHz to 3.5 GHz. Each transmitter channel produces a nominal 1V output and has the most agile frequency, phase and amplitude control of any system on the market. An array of additional options are available including multiple RF transmitters, linear high-power RF amplifiers, digital receiver arrays, low noise figure preamplifiers, a gradient control system, shim unit, MAS spin-speed controller, variable temperature unit, digital lock system and probe/coil interface. With its numerous options, the Apollo can be configured for any NMR, NQR or MRI application.",WEB:<http://www.tecmag.com/apollo.htm>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400249,,,,,,APOLLO console,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000483,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,APOLLO console,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001393,comparative genomic hybridization by array assay,array CGH,An assay in which changes in DNA sequence copy number are analysed using a microarray. For example the analysis of LOH in tumor cells vs a non diseased sample or the comparison of clinical isolated of disease causing bacteria.|Philippe Rocca-Serra,false,,,http://purl.obolibrary.org/obo/OBI_0000435,,http://purl.obolibrary.org/obo/OBI_0000131,,array CGH,,,,,,,,,,,,,,,An assay in which changes in DNA sequence copy number are analysed using a microarray. For example the analysis of LOH in tumor cells vs a non diseased sample or the comparison of clinical isolated of disease causing bacteria.,EFO_0000749: comparative genomic hybridization by array,,,,,,comparative genomic hybridization by array assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0400148,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001305,,,OBI:0001393,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,,,,,,,,,,,,,,,,,,,,,,,,,,,comparative genomic hybridization by array assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: James Malone,,
http://purl.obolibrary.org/obo/OBI_0000536,fraction collector,,"A fraction detector is a device that allows regular or specified samples to be taken from a column eluate and stored in a retrievable form. The storage vessels are usually small sample tubes or vials that are oriented in a rotating disk or in a moving belt, there movement usually being controlled by a microprocessor. On receiving a signal from the microprocessor, the next vial is placed under the column outlet and the eluate collected until receiving another signal from the computer. Once the properties of the chromatogram that describes the separation has been ascertained, then the collection program can be defined. The fractions can be collected on a basis of time either at regular intervals or a specific times to collect specific peaks. Alternatively the fractions can be collected by monitoring the detector output and when a peak starts to elute the fraction collector is activated and the peak collected in a specific vial. When the peak returns to base line the column eluate is then directed to waste until the next peak starts eluting. Fraction collectors are in common use with most liquid chromatographs. They are used to collect samples for further purification, subsequent examination by spectroscopic techniques or for biological or organoleptic testing.",false,,,http://purl.obolibrary.org/obo/OBI_0000485,,,,,,,,,,,,,,,,,,,"A fraction detector is a device that allows regular or specified samples to be taken from a column eluate and stored in a retrievable form. The storage vessels are usually small sample tubes or vials that are oriented in a rotating disk or in a moving belt, there movement usually being controlled by a microprocessor. On receiving a signal from the microprocessor, the next vial is placed under the column outlet and the eluate collected until receiving another signal from the computer. Once the properties of the chromatogram that describes the separation has been ascertained, then the collection program can be defined. The fractions can be collected on a basis of time either at regular intervals or a specific times to collect specific peaks. Alternatively the fractions can be collected by monitoring the detector output and when a peak starts to elute the fraction collector is activated and the peak collected in a specific vial. When the peak returns to base line the column eluate is then directed to waste until the next peak starts eluting. Fraction collectors are in common use with most liquid chromatographs. They are used to collect samples for further purification, subsequent examination by spectroscopic techniques or for biological or organoleptic testing.",WEB:<http://www.chromatography-online.org/topics/fraction/collector.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01073,,,,,,fraction collector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000536,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,fraction collector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/CHEBI_15956,biotin,,"An organic heterobicyclic compound that consists of 2-oxohexahydro-1H-thieno[3,4-d]imidazole having a valeric acid substituent attached to the tetrahydrothiophene ring. The parent of the class of biotins.",false,,,http://purl.obolibrary.org/obo/REO_0000280,,,,,,,,,,,,,,,,,,,"An organic heterobicyclic compound that consists of 2-oxohexahydro-1H-thieno[3,4-d]imidazole having a valeric acid substituent attached to the tetrahydrothiophene ring. The parent of the class of biotins.",,,,,,,biotin,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/REO_0000171,,,,,,,,,,,,CHEBI:15956,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,biotin,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001215,intracellular material detection assay measuring epitope specific perforin release,perforin release|intracellular staining,A T cell epitope specific perforin release assay that uses an intracellular material detection by flow cytometry assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001497,,,,,,,,,,,,,,,,,,,A T cell epitope specific perforin release assay that uses an intracellular material detection by flow cytometry assay.,IEDB,,,,,,intracellular material detection assay measuring epitope specific perforin release,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001215,,,,,,,,,,,,,,,,,,,,,,,,perforin release|intracellular staining,,,,,,,,,,,,,,,,,,,,,,intracellular material detection assay measuring epitope specific perforin release,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0600022,excision,,the use physical means to remove a portion of a substance from the rest,false,,,http://purl.obolibrary.org/obo/OBI_0600014,,http://purl.obolibrary.org/obo/OBI_0000681,,,,,,,,,,,,,,,,,the use physical means to remove a portion of a substance from the rest,www.crohnsresource.com/glossary.jsp (via google define:resection),,,,,,excision,,Cutting out the portion of a gel which contains a DNA fragment,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600022,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,excision,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Alan Ruttenberg, Kevin Clancy",,
http://www.w3.org/2002/07/owl#Thing,Thing,,,false,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,owl:Thing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000375,freeze function,,A freeze function is a function to decrease the internal kinetic energy of a material below the freezing point of that type of material.,false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,A freeze function is a function to decrease the internal kinetic energy of a material below the freezing point of that type of material.,,,,,,,freeze function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000375,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,freeze function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bill Bug|Daniel Schober|Frank Gibson|Melanie Courtot,,
http://purl.obolibrary.org/obo/GO_0010467,gene expression,,The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.,false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.,,,,,,,gene expression,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0010467,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,gene expression,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001914,multiplex ligation-mediated amplification,Multiplex ligation-dependent probe amplification|LMA|MLPA,A polymerase chain reaction that amplifies multiple targets with a single primer pair mediated by hybridization of a primer with its target sequence using ligation.,false,,,http://purl.obolibrary.org/obo/OBI_0000415,,,,Multiplex ligation-dependent probe amplification|LMA|MLPA,,,,,,,,,,,,,,,A polymerase chain reaction that amplifies multiple targets with a single primer pair mediated by hybridization of a primer with its target sequence using ligation.,"web: http://en.wikipedia.org/wiki/Multiplex_Ligation-dependent_Probe_Amplification
Pubmed: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1867615/",,,,,,multiplex ligation-mediated amplification,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0302892,,,,,,,,,,,,,,,,OBI:0001914,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,multiplex ligation-mediated amplification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_1110106,cultured antigen presenting cell population,antigen presenting cell culture sample,a cell culture including cells that have an antigen presentation function,false,,,http://purl.obolibrary.org/obo/OBI_0001875,,,,antigen presenting cell culture sample,,,,,,,,,,,,,,,a cell culture including cells that have an antigen presentation function,IEDB,,,,,,cultured antigen presenting cell population,,A culture of PBMCs. A culture of Hela cells.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110106,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cultured antigen presenting cell population,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_00001975,chromatin immunoprecipitation,ChIP,"An immunoprecipitation in which chromatin (i.e. packaged DNA which can include protein and RNA complexes) is cut into short regions, reversibly cross linked, and antibodies or tags are used to select for pieces of chromatin with desired characteristics.",false,,,http://purl.obolibrary.org/obo/OBI_0000690,,,,ChIP,,,,,,,,,,,,,,,"An immunoprecipitation in which chromatin (i.e. packaged DNA which can include protein and RNA complexes) is cut into short regions, reversibly cross linked, and antibodies or tags are used to select for pieces of chromatin with desired characteristics.",OBI,,,,,,chromatin immunoprecipitation,,"Yang et al, Int J Clin Exp Pathol. 2015; 8(3): 2746–275 PMID:26045780. Cells were lysed and sonicated to shear DNA to lengths between 200-1000 bp. The sample was then incubated with antibodies against Acety-H3 to immunoprecipitate protein-DNA complexes using protein A agarose beads. The isolated protein-DNA complexes were treated with proteinase K digestion to remove histones. QPCR was then performed using primers specific for TGF-β1, MMP-9 and PI3K promoters at 95°C for 5 min, followed by 40 cycles at 95 °C for 20 s, 58°C for 20 s, and 72°C for 20 s. Each QPCR reaction was repeated in triplicate. QPCR was followed by a melt curve analysis to determine the reaction specificity. The relative gene expression was calculated using 2-ΔΔCt method.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:00001975,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,chromatin immunoprecipitation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Bjoern Peters, Randi Vita, James A. Overton",,
http://purl.obolibrary.org/obo/OBI_0500008,balanced incomplete block design,,balanced incomplete block design is a kind of factorial design where all treatment pairs occur together within a block an equal number ?? times. ??ii' is the number of times treatment i occurs with i',false,,,http://purl.obolibrary.org/obo/OBI_0500014,,,,,,,,,,,,,,,,,,,balanced incomplete block design is a kind of factorial design where all treatment pairs occur together within a block an equal number ?? times. ??ii' is the number of times treatment i occurs with i',http://en.wikipedia.org/wiki/Block_design and http://www.stat.psu.edu/~jglenn/stat503/05_factorial/02_factorial_IBD.html,,,,,,balanced incomplete block design,,"PMID: 7622388.Health Educ Q. 1995 May;22(2):201-10.Balanced incomplete block design: description, case study, and implications for practice.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500008,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,balanced incomplete block design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0100062,obsolete_cell line,cell line sample,"A secondary cultured cell population that represents a genetically stable and homogenous population of cultured cells that shares a common propagation history (ie has been successively passaged together in culture).  |1. The term 'line' is used when a culture has undergone an intentional experimental process to establish a more uniform and stable population of cells (see 'establishing cell line'). This will require one or more passages, but may involve additional selection processes. Through such passaging and/or selection processes, the resulting 'line' attains some level of genetic stability and compositional homogeneity which is typically absent in primary cultures. Because of their relative homogeneity, 'lines' are capable of being characterized and stably propagated over a period of time. A *new* cell line can be ""established"" not only through the passaging/selection of a primary culture, but also through experimental modifications of existing lines (e.g. immortalization, stable genetic modifications, drug selection for a resistant subset, etc.).  As defined here,  'cell line' can refer to a population of cells in active culture, applied experimentally, or stored in a quescent state for future use. 

2. The definitional criteria provided here for the 'cell line' class demarcates populations that represent what researchers actually use in the practice of science - e.g. as inputs to culturing, experimentation, and sharing. The definition is such that cell lines will exhibit important attributes. For example, they will have a relatively homogenous cell type composition as they have experienced similar selective pressures due to their continuous co-propagation. In addition, these populations can also be characterized by a passage number, again owing to their common passaging history.?

3. Definitinal criteria are intended to be sufficiently clear to specify what are and what are not instances of 'cell lines' in the real world. A 'HeLa cell line' would be a subset of all HeLa cells in the world - specifically any subset that has been derived through a shared continuous lineage wherein the cells have always been passaged together and thereby evolved together through the selective pressures imposed by this common history. Accordingly, 'HeLa cell line' would not be used to refer to the collection of all HeLa cells in a given lab, or all HeLa cells in the ATCC repository, as cells in these collections will likely not all share a common culture history. Rather, 'HeLa cell line' could refer to the collection of cells I am culturing at a given moment, or that I apply in an experiment (as such collections typically meet the criteria of having a shared propagation history).  As noted above, it is such collections that are typically referred to in scientific discourse and publications.

4. Notably, the term 'line' has been alternately used by other terminologies and communities to refer to cultures that have been immortalized - ie has attained the capacity for indefinite propagation in vitro.  In this ontology, we refer to such cell lines as 'immortal cell lines', and use the term 'cell line' to indicate any culture that has been passaged.",true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,cell line sample,,,,,,,,,,,,,,,A secondary cultured cell population that represents a genetically stable and homogenous population of cultured cells that shares a common propagation history (ie has been successively passaged together in culture).  ,OBI-CLO Alignment Working Group (Spring 2013),,,,,"2013-08-09 MHB: Replaced with cell line class from CLO, follwoing outcome of Spring 2013 CLO alignment work.  Subclass axioms were: 'has grain' some 'cell line cell' and 'has grain' only 'cell line cell'

2013-6-5 MHB: There is considerable ambiguity and inconsistent usage surrounding the term 'cell line' across biomedical communities. For exmaple, it can refer to the maximal collection of all cells in a cultured lineage (e.g. the colelction of all HeLa cells that exist), or to discrete portions of this maximal collection that are stored, exchanged, and applied experimentally (e.g. the dish of HeLa cells I am using in my experiment). A working group of representatives from OBI, CLO, and CL was assembled in spring of 2013 to harmonize modeling and terminology surrounding experimentally cultured cells across Open Biomedical Ontologies, following OBO Foundry principles of orthogonality and re-use. A consensus was reached to apply the term 'cell line' to refer not to a maximal collection of cells of a given type, but to discrete populations of cultured cells that share a common propagation history which has conferred a certain a genetic stability and compositional homogeneity to the population.  This meaning reflects its most common usage in domain discourse, and will best support data annotation requirements. This view means that a 'HeLa cell line' would be a subset of all HeLa cells in the world - specifically any subset that has been derived through a shared continuous lineage wherein the cells have always been passaged together and thereby evolved together through the selective pressures imposed by this specific history. Accordingly, 'HeLa cell line' would not be used to refer to collections such as all HeLa cells in a given lab, or all HeLa cells in the ATCC repository, as all cells in these collections do not necessarily share a common culture history. Rather, it could be used to refer to the collection of cells I am culturing at a given moment, or that I apply in an experiment (as such collections typically meet the criteria of having a shared propagation history).

This approach seems to accomplish several desirable goals:
1) It allows us to define the term 'cell line' for the community in a precise way that also reflects how the term is most commonly used in the literature and scientific discourse.
(2) It gives a definition that provides clear criteria to help specify what are and what are not instances of 'cell lines' in the real world
(3) The criteria it provides demarcate populations that represent what researchers actually use in the practice of science - ie are the inputs to culturing, experimentation, and sharing. The cells in such populations will be a relatively uniform population as they have experienced similar selective pressures due to their continuous co-propagation. And this population will also have a single passage number, again owing to their common passaging history.
(4) The definition seems to be true to the meaning of the word 'line' - which is suggests a specific lineage of derivation.",obsolete_cell line,,"He, Tong-Chuan, et al. \""Identification of c-MYC as a target of the APC pathway.\"" Science 281.5382 (1998): 1509-1512. - \""To evaluate the transcriptional effects of APC, we studied a human colorectal cancer cell line (HT29-APC) containing a zinc-inducible APC gene and a control cell line (HT29–β-Gal) containing an analogous inducible lacZ gene\"".

Note that common usage in the literature is often of the form \""a human colorectal cancer cell line\"", as seen above. But such references to studies in \""a line\"" refer to the fact that discrete populations of cells that are input into culturing or experiments, not an entire lineage of cells.  It is these discrete populations that we refer to as 'cell lines'.|A split of HeLa cells in active culture, or stored in frozen aliquots. Populations of HEK 293 cells used in experiments such as those documented in ""Changes in ultrastructure and endogenous ionic channels activity during culture of HEK 293 cell line"". Eur J Pharmacol. 2007 Jul 12;567(1-2):10-8. PMID: 17482592.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000228,,,,,,,,,,,,,,,,,,OBI:0100062,,,,,,,,,,,,,,,,,,"1. The term 'line' is used when a culture has undergone an intentional experimental process to establish a more uniform and stable population of cells (see 'establishing cell line'). This will require one or more passages, but may involve additional selection processes. Through such passaging and/or selection processes, the resulting 'line' attains some level of genetic stability and compositional homogeneity which is typically absent in primary cultures. Because of their relative homogeneity, 'lines' are capable of being characterized and stably propagated over a period of time. A *new* cell line can be ""established"" not only through the passaging/selection of a primary culture, but also through experimental modifications of existing lines (e.g. immortalization, stable genetic modifications, drug selection for a resistant subset, etc.).  As defined here,  'cell line' can refer to a population of cells in active culture, applied experimentally, or stored in a quescent state for future use. 

2. The definitional criteria provided here for the 'cell line' class demarcates populations that represent what researchers actually use in the practice of science - e.g. as inputs to culturing, experimentation, and sharing. The definition is such that cell lines will exhibit important attributes. For example, they will have a relatively homogenous cell type composition as they have experienced similar selective pressures due to their continuous co-propagation. In addition, these populations can also be characterized by a passage number, again owing to their common passaging history.?

3. Definitinal criteria are intended to be sufficiently clear to specify what are and what are not instances of 'cell lines' in the real world. A 'HeLa cell line' would be a subset of all HeLa cells in the world - specifically any subset that has been derived through a shared continuous lineage wherein the cells have always been passaged together and thereby evolved together through the selective pressures imposed by this common history. Accordingly, 'HeLa cell line' would not be used to refer to the collection of all HeLa cells in a given lab, or all HeLa cells in the ATCC repository, as cells in these collections will likely not all share a common culture history. Rather, 'HeLa cell line' could refer to the collection of cells I am culturing at a given moment, or that I apply in an experiment (as such collections typically meet the criteria of having a shared propagation history).  As noted above, it is such collections that are typically referred to in scientific discourse and publications.

4. Notably, the term 'line' has been alternately used by other terminologies and communities to refer to cultures that have been immortalized - ie has attained the capacity for indefinite propagation in vitro.  In this ontology, we refer to such cell lines as 'immortal cell lines', and use the term 'cell line' to indicate any culture that has been passaged.",,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_cell line,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Matthew Brush,http://purl.obolibrary.org/obo/CLO_0000031,
http://purl.obolibrary.org/obo/OBI_0000388,connection function,,A connection function is a function to couple two or more flow channels so that material or signals can be transported from one set of channels to another.,false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,A connection function is a function to couple two or more flow channels so that material or signals can be transported from one set of channels to another.,,,,,,,connection function,,An electricity cable,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000388,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,connection function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bill Bug|Daniel Schober|Frank Gibson|Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0400039,FACS Scan,,"A FACS_Scan is a flow_cytometer_analyser manufactured by Becton Dickinson. IT features analog electronics, one 488 nm solid state laser, and the filters and PMTs to collect up to three fluorescent parameters The FACS_Scan is usually used for research applications.",false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,,,,,,,,,,,,,,,,"A FACS_Scan is a flow_cytometer_analyser manufactured by Becton Dickinson. IT features analog electronics, one 488 nm solid state laser, and the filters and PMTs to collect up to three fluorescent parameters The FACS_Scan is usually used for research applications.",http://www.brc.ubc.ca/brc/facs.html,,,,,,FACS Scan,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400039,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,FACS Scan,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0000955,electrode puller,,"A device used in the first step in making electrodes, that applies constant tension on a glass capillary tube and eventually breaks it while heating it; this produces a very fine point on the capillary tube.",false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,"A device used in the first step in making electrodes, that applies constant tension on a glass capillary tube and eventually breaks it while heating it; this produces a very fine point on the capillary tube.",http://faculty.plattsburgh.edu/donald.slish/Puller1.html,,,,,,electrode puller,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000379,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000955,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,electrode puller,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000629,Bruker solid magic angle spinning probe,solid MAS probe,"Magic angle spinning, nowadays a routine technique for solids NMR, still offers the capability of innovation. The high mechanical performance of MAS probes in conjunction with efficient rf pulse techniques open new exciting fields in solids NMR of biological samples and in the field of quadrupolar nuclei.",false,,,http://purl.obolibrary.org/obo/OBI_0000561,,,,solid MAS probe,,,,,,,,,,,,,NMR probe,,"Magic angle spinning, nowadays a routine technique for solids NMR, still offers the capability of innovation. The high mechanical performance of MAS probes in conjunction with efficient rf pulse techniques open new exciting fields in solids NMR of biological samples and in the field of quadrupolar nuclei.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400193,,,,,,Bruker solid magic angle spinning probe,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000629,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker solid magic angle spinning probe,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0302887,staining,,"Staining is a process which results in the addition a class-specific (DNA, proteins, lipids, carbohydrates) dye to a substrate to qualify or quantify the presence of a specific compound.",false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,"Staining is a process which results in the addition a class-specific (DNA, proteins, lipids, carbohydrates) dye to a substrate to qualify or quantify the presence of a specific compound.",adapted from Wikipedia: http://en.wikipedia.org/wiki/Staining,,,,,,staining,,PMID: 18540298. Role of modified bleach method in staining of acid-fast bacilli in lymph node aspirates. Acta Cytol. 2008 May-Jun;52(3):325-8.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302887,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,staining,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/GO_0034061,DNA polymerase activity,,Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a nucleic acid template and a 3'hydroxyl group.,false,,,http://purl.obolibrary.org/obo/GO_0003824,,,,,,,,,,,,,,,,,,,Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a nucleic acid template and a 3'hydroxyl group.,,,,,,,DNA polymerase activity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0034061,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,DNA polymerase activity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000701,self-organizing map,SOM,"A self-organizing map (SOM) is an artificial neural network with objective class discovery that uses a neighborhood function to preserve the topological properties of a dataset to produce low-dimensional (typically 2) discretized representation of the training data set. A set of artificial neurons learn to map points in an input space to coordinates in an output space. The input space can have different dimensions and topology from the output space, and the SOM will attempt to preserve these.",false,,,http://purl.obolibrary.org/obo/OBI_0200175,,,,SOM,,,,,,,,,,,,,,,"A self-organizing map (SOM) is an artificial neural network with objective class discovery that uses a neighborhood function to preserve the topological properties of a dataset to produce low-dimensional (typically 2) discretized representation of the training data set. A set of artificial neurons learn to map points in an input space to coordinates in an output space. The input space can have different dimensions and topology from the output space, and the SOM will attempt to preserve these.",PERSON: Ryan Brinkman,,,,,,self-organizing map,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000701,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,self-organizing map,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Ryan Brinkman|James Malone,,
http://purl.obolibrary.org/obo/OBI_0200055,dye swap merge,,"A dye swap merge is a replicate analysis which takes as input data from paired two-channel microarray assays where the sample labeled with one dye in the first assay is labeled with the other dye in the second assay and vice versa. The output for each reporter is obtained by combining its (raw or possibly pre-processed) M values in the two assays, where the M value in an assay is defined as the difference of the log intensities in the two channels. This can be used as a normalization step, when appropriate assumptions are met.",false,,,http://purl.obolibrary.org/obo/OBI_0200057,,,,,,,,,,,,,,,,,,,"A dye swap merge is a replicate analysis which takes as input data from paired two-channel microarray assays where the sample labeled with one dye in the first assay is labeled with the other dye in the second assay and vice versa. The output for each reporter is obtained by combining its (raw or possibly pre-processed) M values in the two assays, where the M value in an assay is defined as the difference of the log intensities in the two channels. This can be used as a normalization step, when appropriate assumptions are met.",PERSON: Elisabetta Manduchi|PERSON: James Malone,,,,,,dye swap merge,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200055,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,dye swap merge,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0000543,syringe filter,,"A small membrane filter of defined pore size, that filters samples from a syringe.",false,,,http://purl.obolibrary.org/obo/OBI_0000592,,,,,,,,,,,,,,,,,,,"A small membrane filter of defined pore size, that filters samples from a syringe.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01122,,,,,,syringe filter,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000543,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,syringe filter,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0200075,row submatrix extraction,,A row submatrix extraction is a submatrix extraction where all the columns of the input matrix are retained and selection only occurs on the rows.,false,,,http://purl.obolibrary.org/obo/OBI_0200074,,,,,,,,,,,,,,,,,,,A row submatrix extraction is a submatrix extraction where all the columns of the input matrix are retained and selection only occurs on the rows.,PERSON: Elisabetta Manduchi|PERSON: James Malone|PERSON: Melanie Courtot,,,,,,row submatrix extraction,,"When presented with the data from an expression microarray experiment in the form of a matrix, whose rows correspond to genes and whose columns correspond to samples, if one filters some of the genes out, the resulting data set corresponds to a row submatrix of the original set.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200075,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,row submatrix extraction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Melanie Courtot|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0001724,biological activity assay measuring epitope specific hemagglutination inhibition,hemagglutination inhibition|biological activity,A B cell epitope qualitative binding to antibody assay that uses a viral hemagglutination inhibition assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001703,,,,,,,,,,,,,,,,,,,A B cell epitope qualitative binding to antibody assay that uses a viral hemagglutination inhibition assay.,IEDB,,,,,,biological activity assay measuring epitope specific hemagglutination inhibition,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001724,,,,,,,,,,,,,,,,,,,,,,,,hemagglutination inhibition|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific hemagglutination inhibition,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001172,dose response curve,,"A data item of paired values, one indicating the dose of a material, the other quantitating a measured effect at that dose. The dosing intervals are chosen so that effect values be interpolated by a plotting a curve. ",false,,,http://purl.obolibrary.org/obo/IAO_0000573,,,,,,,,,,,,,,,,,,,"A data item of paired values, one indicating the dose of a material, the other quantitating a measured effect at that dose. The dosing intervals are chosen so that effect values be interpolated by a plotting a curve. ",,,,,,,dose response curve,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001172,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,dose response curve,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters; Randi Vita,,
http://purl.obolibrary.org/obo/OBI_0001673,nano-cap analysis of gene expression ,nano-CAGE,nano-CAGE is a type of CAGE developed to work from very low amount (nanogram scale) of mRNA samples,false,,,http://purl.obolibrary.org/obo/OBI_0000070|http://purl.obolibrary.org/obo/OBI_0000424,,,,nano-CAGE,,,,,,,,,,,,,,,nano-CAGE is a type of CAGE developed to work from very low amount (nanogram scale) of mRNA samples,PMID: 20543846,,,,,,nano-cap analysis of gene expression ,,"Linking promoters to functional transcripts in small samples with nanoCAGE and CAGEscan. 
PMID:20543846
",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001673,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,nano-cap analysis of gene expression ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra; Marcus Chibucos,,
http://purl.obolibrary.org/obo/OBI_0000727,k-nearest neighbors,k-NN,"A k-nearest neighbors is a data transformation which achieves a class discovery or partitioning objective, in which an input data object with vector y is assigned to a class label based upon the k closest training data set points to y; where k is the largest value that class label is assigned.",false,,,http://purl.obolibrary.org/obo/OBI_0200171|http://purl.obolibrary.org/obo/OBI_0200175,,http://purl.obolibrary.org/obo/OBI_0200172,,k-NN,,,,,,,,,,,,,,,"A k-nearest neighbors is a data transformation which achieves a class discovery or partitioning objective, in which an input data object with vector y is assigned to a class label based upon the k closest training data set points to y; where k is the largest value that class label is assigned.",PERSON: James Malone,,,,,,k-nearest neighbors,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000727,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,k-nearest neighbors,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_1110199,epitope specific IL-4 release by T cells,,A biological process where T cells produce IL-4 resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/OBI_0001193|http://purl.obolibrary.org/obo/GO_0032633,,,,,,,,,,,,,,,,,,,A biological process where T cells produce IL-4 resulting from the recognition of a T cell epitope.,IEDB,,,,,,epitope specific IL-4 release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110199,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific IL-4 release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001143,labeled nucleic acid extract,labeled extract|labeled extract,a labeled specimen that is the output of a labeling process and has grain labeled nucleic acid for detection of the nucleic acid in future experiments.,false,,,http://purl.obolibrary.org/obo/OBI_0000924,,,,labeled extract,,,,,,,,,,,,,,,a labeled specimen that is the output of a labeling process and has grain labeled nucleic acid for detection of the nucleic acid in future experiments.,MO_221 labeledExtract,,,,,,labeled nucleic acid extract,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,http://purl.obolibrary.org/obo/CHEBI_33696,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001143,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,labeled extract,labeled nucleic acid extract,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jie Zheng,,
http://purl.obolibrary.org/obo/CHEBI_24636,proton,,"Nuclear particle of charge number +1, spin 1/2 and rest mass of 1.007276470(12) u.",false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,"Nuclear particle of charge number +1, spin 1/2 and rest mass of 1.007276470(12) u.",,,,,,,proton,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:24636,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,proton,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001120,portable fluorometer,,A compact fluorometer that can be carried or moved with ease.,false,,,http://purl.obolibrary.org/obo/OBI_0400143,,,,,,,,,,,,,,,,,,,A compact fluorometer that can be carried or moved with ease.,PERSON: Erik Segerdell,,,,,,portable fluorometer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,portable fluorometer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0000410,recombinant plasmid,,a plasmid in which extraneous DNA has been inserted.,false,,,http://purl.obolibrary.org/obo/OBI_0000731|http://purl.obolibrary.org/obo/OBI_0000430,,,,,,,,,,,,,,,,,,,a plasmid in which extraneous DNA has been inserted.,GROUP: OBI Biomaterial Branch,,,,,,recombinant plasmid,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000410,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,recombinant plasmid,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot|PERSON: Kevin Clancy|PERSON: Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001645,calorimetry assay measuring binding of a B cell epitope:antibody complex ,qualitative binding|calorimetry,A B cell epitope qualitative binding to antibody assay that uses a calorimetric binding assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001703,,,,,,,,,,,,,,,,,,,A B cell epitope qualitative binding to antibody assay that uses a calorimetric binding assay.,IEDB,,,,,,calorimetry assay measuring binding of a B cell epitope:antibody complex ,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001645,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|calorimetry,,,,,,,,,,,,,,,,,,,,,,calorimetry assay measuring binding of a B cell epitope:antibody complex ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/GO_0001913,T cell mediated cytotoxicity,,The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.,false,,,http://purl.obolibrary.org/obo/GO_0001906,,,,,,,,,,,,,,,,,,,The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.,,,,,,,T cell mediated cytotoxicity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0001913,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,T cell mediated cytotoxicity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000638,gas purifier,,"Gas purifiers are instruments used for the removal of gas impurities like hydrocarbons, oxygen, and moisture from carrier gas and fuel gases for GC or GC-MS systems.",false,,,http://purl.obolibrary.org/obo/OBI_0000542,,,,,,,,,,,,,,,,,gas chromatography equipment,,"Gas purifiers are instruments used for the removal of gas impurities like hydrocarbons, oxygen, and moisture from carrier gas and fuel gases for GC or GC-MS systems.",WEB:<http://www.sigmaaldrich.com/Area_of_Interest/Analytical__Chromatography/Gas_Chromatography/Accessories/SGT_Gas_Purifier.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01036,,,,,,gas purifier,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000638,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,gas purifier,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000824,recombinant YAC cloning,,Recombinant YAC cloning is a  process with the objective to insert genetic material into a yeast artificial chromosome vector for future replication of the inserted material,false,,,http://purl.obolibrary.org/obo/OBI_0600064,,,,,,,,,,,,,,,,,,,Recombinant YAC cloning is a  process with the objective to insert genetic material into a yeast artificial chromosome vector for future replication of the inserted material,http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=mcb.section.1611,,,,,,recombinant YAC cloning,,Isolation of a YAC clone covering a cluster of nine S100 genes on human chromosome 1q21,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000824,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,recombinant YAC cloning,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Helen Parkinson,,
http://purl.obolibrary.org/obo/PR_000025477,ribonuclease V1,,A protein with ribonuclease activity that is a constituent of cobra venom.,false,,,http://purl.obolibrary.org/obo/PR_000000001,,,,,,,,,,,,,,,,,,,A protein with ribonuclease activity that is a constituent of cobra venom.,,,,,,,ribonuclease V1,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PR:000025477,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pr.owl,,,,,,,,,,,,,,,,,,,ribonuclease V1,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PR_000025475,ribonuclease U2,,A protein that is a translation product of the Ustilago sphaerogena RNU2 gene or a 1:1 ortholog thereof.,false,,,http://purl.obolibrary.org/obo/PR_000000001,,,,,,,,,,,,,,,,,,,A protein that is a translation product of the Ustilago sphaerogena RNU2 gene or a 1:1 ortholog thereof.,,,,,,,ribonuclease U2,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PR:000025475,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pr.owl,,,,,,,,,,,,,,,,,,,ribonuclease U2,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PR_000025471,nuclease S1,,A protein that is a translation product of the Aspergillus oryzae nucS gene or a 1:1 ortholog thereof.,false,,,http://purl.obolibrary.org/obo/PR_000000001,,,,,,,,,,,,,,,,,,,A protein that is a translation product of the Aspergillus oryzae nucS gene or a 1:1 ortholog thereof.,,,,,,,nuclease S1,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PR:000025471,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pr.owl,,,,,,,,,,,,,,,,,,,nuclease S1,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PR_000025478,ribonuclease CL3,,A protein with ribonuclease activity that is purified from chicken liver.,false,,,http://purl.obolibrary.org/obo/PR_000000001,,,,,,,,,,,,,,,,,,,A protein with ribonuclease activity that is purified from chicken liver.,,,,,,,ribonuclease CL3,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PR:000025478,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pr.owl,,,,,,,,,,,,,,,,,,,ribonuclease CL3,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001175,selective organism creation objective,,"an objective specification to generate a population or type of organism within species that have some uniform behavioral, morphological, physiological, or genetic characteristics with similarly bred organisms.",false,,,http://purl.obolibrary.org/obo/IAO_0000005,,,,,,,,,,,,,,,,,,,"an objective specification to generate a population or type of organism within species that have some uniform behavioral, morphological, physiological, or genetic characteristics with similarly bred organisms.","WEB: wikipedia
http://en.wikipedia.org/wiki/Cultivar
http://en.wikipedia.org/wiki/Ecotype
http://en.wikipedia.org/wiki/Strain_%28biology%29",,,,,,selective organism creation objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001175,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,selective organism creation objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001801,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-8 production by T cells,IL-8 release|RNA/DNA detection,An assay of epitope specific interleukin-8 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001218,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-8 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-8 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001801,,,,,,,,,,,,,,,,,,,,,,,,IL-8 release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-8 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001628,investigation identifier,project ID,A CRID symbol used to identify an investigation.,false,,,http://purl.obolibrary.org/obo/IAO_0000577,,,,,,,,,,,,,,,,,,,A CRID symbol used to identify an investigation.,NIAID GSCID-BRC metadata working group,,,,,,investigation identifier,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001628,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,investigation identifier,,,,,,project ID,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"Person: Chris Stoeckert, Jie Zhneg",,
http://purl.obolibrary.org/obo/OBI_0001429,cell differentiation design,,A study design that assays events associated with cell development or differentiation.,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,A study design that assays events associated with cell development or differentiation.,MO_892 development_or_differentiation_design,,,,,,cell differentiation design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001429,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cell differentiation design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001484,biological activity assay measuring T cell epitope specific in vivo activity,in vivo activity|biological activity,A T cell epitope dependent biological activity determination assay that uses an in vivo intervention experiment.,false,,,http://purl.obolibrary.org/obo/OBI_0002055,,,,,,,,,,,,,,,,,,,A T cell epitope dependent biological activity determination assay that uses an in vivo intervention experiment.,IEDB,,,,,,biological activity assay measuring T cell epitope specific in vivo activity,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001484,,,,,,,,,,,,,,,,,,,,,,,,in vivo activity|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring T cell epitope specific in vivo activity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/BFO_0000016,disposition,,,false,,,http://purl.obolibrary.org/obo/BFO_0000017,,,,,,,Disposition,disposition,,,,,,,,,,,,,,,,,BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type.,disposition,"b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])",an atom of element X has the disposition to decay to an atom of element Y|children are innately disposed to categorize objects in certain ways.|certain people have a predisposition to colon cancer|the cell wall is disposed to filter chemicals in endocytosis and exocytosis,,,,,,,,(forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] |(forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] ,"If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000016,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,disposition,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0100058,xenograft,xenotransplant,"A material entity which results from the transplantation of living cells, tissues or organs  from on organism of one species to an organism of another species.",false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,xenotransplant,,,,,,,,,,,,,,,"A material entity which results from the transplantation of living cells, tissues or organs  from on organism of one species to an organism of another species.",WEB: http://en.wikipedia.org/wiki/Xenograft,,http://purl.obolibrary.org/obo/OBI_0100026,,,,xenograft,,"Human xenotransplantation (e.g. from pig to human) offers a potential treatment for end-stage organ failure, a significant health problem in parts of the industrialized world",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0100058,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000105,,,xenograft,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot|PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001722,B cell epitope specific hypersensitivity,,hypersensitivity resulting from antibody binding to epitope,false,,,http://purl.obolibrary.org/obo/GO_0002524,,,,,,,,,,,,,,,,,Date: 2012-05-03; Spreadsheet: BcellAssays.xls; Worksheet: Especific template; Mapping: ebcell_specific_mappings.owl,,hypersensitivity resulting from antibody binding to epitope,IEDB (QTT),,,,,,B cell epitope specific hypersensitivity,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001722,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,B cell epitope specific hypersensitivity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000427,enzyme,,"(protein or rna) or has_part (protein or rna) and
has_function some GO:0003824 (catalytic activity)",false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,"(protein or rna) or has_part (protein or rna) and
has_function some GO:0003824 (catalytic activity)",GROUP:OBI,,,,,"MC: known issue: enzyme doesn't classify under material entity for now as it isn't stated that anything
that has_part some material entity is a material entity. If we add as equivalent classes to material entity has_part some material entity and part_of some material entity  (each one in his own necessary and sufficient block) Pellet in P3 doesn't classify any more.",enzyme,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000427,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,enzyme,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person: Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0001459,biological activity assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells,CXCL9/MIG release|biological activity,A T cell epitope specific cytokine production assay that detects chemokine (C-X-C motif) ligand 9 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects chemokine (C-X-C motif) ligand 9 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001459,,,,,,,,,,,,,,,,,,,,,,,,CXCL9/MIG release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001468,cell specimen,,A specimen primarily composed of cells collected from a multicellular organism or a cell culture,false,,,http://purl.obolibrary.org/obo/OBI_0100051,,,,,,,,,,,,,,,,,,,A specimen primarily composed of cells collected from a multicellular organism or a cell culture,MO_612 cell,,,,,,cell specimen,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,http://purl.obolibrary.org/obo/CL_0000000,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000112,,,,,,,,,,,,OBI:0001468,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cell specimen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001337,clinical history design,,"A study design that the organism's clinical history of diagnosis, treatments, e.g. vaccinations, surgery etc. is studied.",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A study design that the organism's clinical history of diagnosis, treatments, e.g. vaccinations, surgery etc. is studied.",MO_832 clinical_history_design,,,,,,clinical history design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001337,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,clinical history design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001317,flow cytometry assay measuring cell-cell binding of a T cell epitope:MHC:TCR complex,T cell- APC binding|binding assay,A T cell epitope qualitative binding assay that uses a cell-cell binding detection by flow cytometry assay.,false,,,http://purl.obolibrary.org/obo/OBI_1110124|http://purl.obolibrary.org/obo/OBI_0001499,,,,,,,,,,,,,,,,,,,A T cell epitope qualitative binding assay that uses a cell-cell binding detection by flow cytometry assay.,IEDB,,,,,,flow cytometry assay measuring cell-cell binding of a T cell epitope:MHC:TCR complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001317,,,,,,,,,,,,,,,,,,,,,,,,T cell- APC binding|binding assay,,,,,,,,,,,,,,,,,,,,,,flow cytometry assay measuring cell-cell binding of a T cell epitope:MHC:TCR complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/CHEBI_33709,amino acid,,A carboxylic acid containing one or more amino groups.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,A carboxylic acid containing one or more amino groups.,,,,,,,amino acid,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:33709,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,amino acid,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001767,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-C motif) ligand 19 production by T cells,CCL19/MIP-3b release|RNA/DNA detection,An assay of epitope specific chemokine (C-C motif) ligand 19 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001775,,,,,,,,,,,,,,,,,,,An assay of epitope specific chemokine (C-C motif) ligand 19 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-C motif) ligand 19 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001767,,,,,,,,,,,,,,,,,,,,,,,,CCL19/MIP-3b release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-C motif) ligand 19 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/GO_0003823,antigen binding,,"Interacting selectively and non-covalently with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.",false,,,http://purl.obolibrary.org/obo/BFO_0000015,,,,,,,,,,,,,,,,,,,"Interacting selectively and non-covalently with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.",,,,,,,antigen binding,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0003823,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,antigen binding,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0003824,catalytic activity,,"Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.",false,,,http://purl.obolibrary.org/obo/GO_0003674,,,,,,,,,,,,,,,,,,,"Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.",,,,,,,catalytic activity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0003824,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,catalytic activity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001128,micropipette,,A microinjection device that is used to measure very small volumes of liquids.,false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,A microinjection device that is used to measure very small volumes of liquids.,http://www.answers.com/topic/micropipette,,,,,,micropipette,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453|http://purl.obolibrary.org/obo/OBI_0000379,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001128,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,micropipette,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001187,infectious agent detection assay,,"An assay in which the presence or amount of an infectious agent in an input material is detected in an evaluant
",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,"An assay in which the presence or amount of an infectious agent in an input material is detected in an evaluant
",,,,,,"2/22/2011, BP: This should probably be an analyte assay, but the logical definition of those is currently restricted to 'scattered molecular aggregates', which excludes using infectious agents as analytes. See below
(realizes some 
    ('evaluant role'
     and (role_of some material_entity)))
 and (realizes some 
    ('analyte role'
     and (role_of some 'infectious agent')))
 and (achieves_planned_objective some 'analyte measurement objective')",infectious agent detection assay,,"Culturing a sputum sample on agar medium to detect bacterial growth; Stain slices of liver from a mouse to count presence of infectious centers. 
",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001187,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,infectious agent detection assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Bjoern Peters, Randi Vita, Jason Greenbaum",,
http://purl.obolibrary.org/obo/IAO_0000010,software,,"Software is a plan specification composed of a series of instructions that can be 
interpreted by or directly executed by a processing unit.",false,,,http://purl.obolibrary.org/obo/IAO_0000104,,,,,,,,,,,,,,,,,,,"Software is a plan specification composed of a series of instructions that can be 
interpreted by or directly executed by a processing unit.",GROUP: OBI,,,,,see sourceforge tracker discussion at http://sourceforge.net/tracker/index.php?func=detail&aid=1958818&group_id=177891&atid=886178,software,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000010,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,software,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters|PERSON: Melanie Courtot|PERSON: Chris Stoeckert|PERSON: Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0500020,time series design,,Groups of assays that are related as part of a time series.,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,Groups of assays that are related as part of a time series.,MO_887,,,,,,time series design,,"PMID: 14744830-Microarrays are powerful tools for surveying the expression levels of many thousands of genes simultaneously. They belong to the new genomics technologies which have important applications in the biological, agricultural and pharmaceutical sciences. There are myriad sources of uncertainty in microarray experiments, and rigorous experimental design is essential for fully realizing the potential of these valuable resources. Two questions frequently asked by biologists on the brink of conducting cDNA or two-colour, spotted microarray experiments are 'Which mRNA samples should be competitively hybridized together on the same slide?' and 'How many times should each slide be replicated?' Early experience has shown that whilst the field of classical experimental design has much to offer this emerging multi-disciplinary area, new approaches which accommodate features specific to the microarray context are needed. In this paper, we propose optimal designs for factorial and time course experiments, which are special designs arising quite frequently in microarray experimentation. Our criterion for optimality is statistical efficiency based on a new notion of admissible designs; our approach enables efficient designs to be selected subject to the information available on the effects of most interest to biologists, the number of arrays available for the experiment, and other resource or practical constraints, including limitations on the amount of mRNA probe. We show that our designs are superior to both the popular reference designs, which are highly inefficient, and to designs incorporating all possible direct pairwise comparisons. Moreover, our proposed designs represent a substantial practical improvement over classical experimental designs which work in terms of standard interactions and main effects. The latter do not provide a basis for meaningful inference on the effects of most interest to biologists, nor make the most efficient use of valuable and limited resources.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500020,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,time series design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra on behalf of MO,,
http://purl.obolibrary.org/obo/OBI_0001737,obsolete B cell epitope specific X-ray crystallography assay,X-ray crystallography [Ã…],A X-ray crystallography assay measuring epitope specfic antibody binding event in angstroms,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,A X-ray crystallography assay measuring epitope specfic antibody binding event in angstroms,IEDB (QTT),,,,,,obsolete B cell epitope specific X-ray crystallography assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000227,,,,,,,,,,,,,,,,,,OBI:0001737,,,,,,,,,,,,,,,,,,,,,,,,X-ray crystallography [Ã…],,,,,,,,,,,,,,,,,,,,,,obsolete B cell epitope specific X-ray crystallography assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",http://purl.obolibrary.org/obo/OBI_0001738,
http://purl.obolibrary.org/obo/OBI_0200113,similarity calculation,,A similarity calculation is a data transformation that attaches to each pair of objects in the input a number that is meant to reflect how 'close' or 'similar' those objects are.,false,,,http://purl.obolibrary.org/obo/OBI_0200175|http://purl.obolibrary.org/obo/OBI_0000663,,,,,,,,,,,,,,,,,,,A similarity calculation is a data transformation that attaches to each pair of objects in the input a number that is meant to reflect how 'close' or 'similar' those objects are.,PERSON: Elisabetta Manduchi,,,,,,similarity calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000648|http://purl.obolibrary.org/obo/OBI_0000023,,,OBI:0200113,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,similarity calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0302868,mean-centered data,,a data item which has been processed by a mean centering data transformation where each output value is produced by subtracting the mean from the inout value,false,,,http://purl.obolibrary.org/obo/OBI_0000451,,,,,,,,,,,,,,,,,,,a data item which has been processed by a mean centering data transformation where each output value is produced by subtracting the mean from the inout value,,,,,,,mean-centered data,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302868,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,mean-centered data,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Helen Parkinson|Person:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0400170,microscope slide,,a microscope slide is a device usually made of glass which is used as a solid matrix for (biological) material deposited on its surface and which is compatible for use with a microscope instrument,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,a microscope slide is a device usually made of glass which is used as a solid matrix for (biological) material deposited on its surface and which is compatible for use with a microscope instrument,OBI biomaterial branch,,,,,,microscope slide,,PMID: 9668975.Microscope slide for enhanced analysis of DNA damage using the comet assay.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000399,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400170,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,microscope slide,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Phillippe Rocca-Serra,,
http://purl.obolibrary.org/obo/SO_0000353,sequence_assembly,,A sequence of nucleotides that has been algorithmically derived from an alignment of two or more different sequences.,false,,,http://purl.obolibrary.org/obo/SO_0001248,,,,,,,,,,,,,,,,,,,A sequence of nucleotides that has been algorithmically derived from an alignment of two or more different sequences.,,,,,,,sequence_assembly,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,SO:0000353,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/so.owl,,,,,,,,,,,,,,,,,,,sequence_assembly,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000980,obsolete_protocol service provider role,,a service provider role which is realized by a servicer provider organization performing a protocol execution,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,a service provider role which is realized by a servicer provider organization performing a protocol execution,,,,,,"obsolete during the San Diego workshop, March 2011
The reason is that we decided to pursue a different modeling approach for services keeping just the 'service consumer' and 'service provider' roles and differentiate just at the level of planned process offered a s service.",obsolete_protocol service provider role,,DNA sequencing of a sample by a core lab which returns data to the consumer,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,OBI:0000980,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_protocol service provider role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0000814,guar gum,,"Guar gum, also called guaran, is a galactomannan. It is primarily the ground endosperm of guar beans. The guar seeds are dehusked, milled and screened to obtain the guar gum.[1] It is typically produced as a free flowing, pale, off-white colored, coarse to fine ground powder.",false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,"Guar gum, also called guaran, is a galactomannan. It is primarily the ground endosperm of guar beans. The guar seeds are dehusked, milled and screened to obtain the guar gum.[1] It is typically produced as a free flowing, pale, off-white colored, coarse to fine ground powder.",http://en.wikipedia.org/wiki/Guar_gum,,,,,,guar gum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000814,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,guar gum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0001632,immuno staining assay,,A detection of molecular label assay in which the label is attached to an antibody so that substances are marked based on the antibody's binding specificity.,false,,,http://purl.obolibrary.org/obo/OBI_0600017,,,,,,,,,,,,,,,,,,,A detection of molecular label assay in which the label is attached to an antibody so that substances are marked based on the antibody's binding specificity.,IEDB,,,,,,immuno staining assay,,Detection of the presence of VCAM molecules on the surface of cells in a histology slide using an enzyme-linked antibody followed by enzyme activation to release a dye.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001632,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,immuno staining assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001571,equilibrium dissociation constant (KD) approximated by IC50,,"A measurement of an IC50 value under specific assay conditions approximates KD, namely the binding reaction is at an equilibrium, there is a single population of sites on the receptor that competitor and ligand are binding to, and the concentration of the receptor must be much less than the KD for the competitor and the ligand.  In this case, according to Cheng and Prussoff, KD = IC50 / (1 + Lstot / KDs), in which Lstot is the total concentration of the labeled competitor and KDs is the KD value of that competitor. ",false,,,http://purl.obolibrary.org/obo/OBI_0001191|http://purl.obolibrary.org/obo/OBI_0001144,,,,,,,,,,,,,,,,,,,"A measurement of an IC50 value under specific assay conditions approximates KD, namely the binding reaction is at an equilibrium, there is a single population of sites on the receptor that competitor and ligand are binding to, and the concentration of the receptor must be much less than the KD for the competitor and the ligand.  In this case, according to Cheng and Prussoff, KD = IC50 / (1 + Lstot / KDs), in which Lstot is the total concentration of the labeled competitor and KDs is the KD value of that competitor. ","http://dx.doi.org/10.1016/0006-2952(73)90196-2
",,,,,,equilibrium dissociation constant (KD) approximated by IC50,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001571,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,equilibrium dissociation constant (KD) approximated by IC50,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Bjoern Peters, Randi Vita",,
http://purl.obolibrary.org/obo/OBI_0001691,cellular structure feature identification objective,,is an objective specification which aims to discover cellular structure properties,false,,,http://purl.obolibrary.org/obo/OBI_0000015,,,,,,,,,,,,,,,,,,,is an objective specification which aims to discover cellular structure properties,OBI group,,,,,,cellular structure feature identification objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001691,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cellular structure feature identification objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0200156,data partitioning,,Data partitioning is a data transformation with the objective of partitioning or separating input data into output subsets.,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,Data partitioning is a data transformation with the objective of partitioning or separating input data into output subsets.,PERSON: Melanie Courtot|PERSON: Ryan Brinkman|PERSON: Richard Scheuermann,,,,,,data partitioning,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200156,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,data partitioning,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0001177,RNA sequencing,,RNA sequencing is a sequencing process which uses ribonucleic acid as input and results in a the creation of RNA sequence information artifact ,false,,,http://purl.obolibrary.org/obo/OBI_0600047,,,,,,,,,,,,,,,,,,,RNA sequencing is a sequencing process which uses ribonucleic acid as input and results in a the creation of RNA sequence information artifact ,Bjoern Peters,,,,,BP 12/21:Created based on a request from Melanie,RNA sequencing,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001177,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,RNA sequencing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0400080,optical subsystem,,"a device or part of a device that deals with the behavior and properties of light and the interaction of light with matter. Commonly optical subsystems consist of an excitation optics and collection optics. The excitation optics of a flow cytometer optical subsystem consist of the laser and lenses that are used to shape and focus the laser beam. The collections optics consist of a collection lens to collect light emitted from the particle laser beam interaction and a system of optical mirrors and filters to route specified wavelengths of the collected light to designated optical detectors. The optical subsystem in a flow cytometer consists of the equipment used to irradiate particles, and collect the light either emitted or scattered by those particles.",false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,"a device or part of a device that deals with the behavior and properties of light and the interaction of light with matter. Commonly optical subsystems consist of an excitation optics and collection optics. The excitation optics of a flow cytometer optical subsystem consist of the laser and lenses that are used to shape and focus the laser beam. The collections optics consist of a collection lens to collect light emitted from the particle laser beam interaction and a system of optical mirrors and filters to route specified wavelengths of the collected light to designated optical detectors. The optical subsystem in a flow cytometer consists of the equipment used to irradiate particles, and collect the light either emitted or scattered by those particles.",John Quinn,,,,,"DS: Is 'subsystem' necessary or is 'optical_system' enough. Not sure its graph position since an optical subsystem is not necessarily an instrument, but more likely part of one.",optical subsystem,,optical subsystem of a cytometer,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0400079|http://purl.obolibrary.org/obo/OBI_0400065|http://purl.obolibrary.org/obo/OBI_0400078,,,,,,,,,,,,,,,,OBI:0400080,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,optical subsystem,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001061,microwave synthesis system,,A device that is used to apply microwave irradiation to chemical reactions.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A device that is used to apply microwave irradiation to chemical reactions.,http://en.wikipedia.org/wiki/Microwave_chemistry,,,,,,microwave synthesis system,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000376|http://purl.obolibrary.org/obo/OBI_0000374,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001061,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,microwave synthesis system,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0000700,support vector machine,SVM,A support vector machine is a data transformation with a class prediction objective based on the construction of a separating hyperplane that maximizes the margin between two data sets of vectors in n-dimensional space.,false,,,http://purl.obolibrary.org/obo/OBI_0000663,,http://purl.obolibrary.org/obo/OBI_0200179,,SVM,,,,,,,,,,,,,,,A support vector machine is a data transformation with a class prediction objective based on the construction of a separating hyperplane that maximizes the margin between two data sets of vectors in n-dimensional space.,PERSON: Ryan Brinkman,,,,,,support vector machine,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000700,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,support vector machine,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Ryan Brinkman|James Malone,,
http://purl.obolibrary.org/obo/PATO_0001792,left side of,,A spatial quality inhering in a bearer by virtue of the bearer's being located on left side of from the a another entity.,false,,,http://purl.obolibrary.org/obo/PATO_0001631,,,,,,,,,,,,,,,,,,,A spatial quality inhering in a bearer by virtue of the bearer's being located on left side of from the a another entity.,,,,,,,left side of,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001792,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,left side of,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0001793,right side of,,A spatial quality inhering in a bearer by virtue of the bearer's being located on right side of a another entity.,false,,,http://purl.obolibrary.org/obo/PATO_0001631,,,,,,,,,,,,,,,,,,,A spatial quality inhering in a bearer by virtue of the bearer's being located on right side of a another entity.,,,,,,,right side of,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001793,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,right side of,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001389,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-6 production by T cells,IL-6 release|RNA/DNA detection,An assay of epitope specific interleukin-6 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001451,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-6 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-6 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001389,,,,,,,,,,,,,,,,,,,,,,,,IL-6 release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-6 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0500027,inclusion criteria,inclusion rule|inclusion condition,"an inclusion criterion (rule) is_a *eligibility criterion*  which defines and states a condition which, if met, makes an entity suitable for a given task or participation in a given process. For instance, in a study protocol, inclusion criteria indicate the conditions that prospective subjects MUST meet to be eligible for participation in a study.",false,,,http://purl.obolibrary.org/obo/OBI_0500026,,,,inclusion rule|inclusion condition,,,,,,,,,,,,,,,"an inclusion criterion (rule) is_a *eligibility criterion*  which defines and states a condition which, if met, makes an entity suitable for a given task or participation in a given process. For instance, in a study protocol, inclusion criteria indicate the conditions that prospective subjects MUST meet to be eligible for participation in a study.",Adapted from Clinical Research Glossary Version 4.0 CDICS glossary group,,,,,,inclusion criteria,,PMID: 23979341-The major inclusion criterion was patients in whom severe cerebral embolism was diagnosed at age 75 or younger (more than 9 in the NIHSS score on day 7 after the onset of stroke) .,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500027,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,inclusion criteria,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001333,biological activity assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells,CCL3/MIP-1a release|biological activity,A T cell epitope specific cytokine production assay that detects macrophage inflammatory protein-1 alpha production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects macrophage inflammatory protein-1 alpha production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001333,,,,,,,,,,,,,,,,,,,,,,,,CCL3/MIP-1a release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001576,obsolete purified MHC binding constant determination assay,,An assay that measures the affinity of a ligand to a purified MHC complex preparation and that quantifies the affinity with a binding constant.,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,An assay that measures the affinity of a ligand to a purified MHC complex preparation and that quantifies the affinity with a binding constant.,IEDB,,,,,,obsolete purified MHC binding constant determination assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,OBI:0001576,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete purified MHC binding constant determination assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters,,
http://purl.obolibrary.org/obo/BFO_0000017,realizable entity,,"A specifically dependent continuant  that inheres in continuant  entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances.",false,,,http://purl.obolibrary.org/obo/BFO_0000020,,,,,,,RealizableEntity,realizable,,,,,,,,,,,"A specifically dependent continuant  that inheres in continuant  entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances.",,,,,,,realizable entity,To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002]),the disposition of your blood to coagulate|the role of being a doctor|the role of this boundary to delineate where Utah and Colorado meet|the disposition of this piece of metal to conduct electricity.|the function of your reproductive organs,,,,,,,,(forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] |(forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] ,All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002]),,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000017,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,realizable entity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001745,ELISPOT assay measuring epitope specific interleukin-1 alpha production by T cells,IL-1a release|ELISPOT,An assay of epitope specific interleukin-1 alpha production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001388,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-1 alpha production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific interleukin-1 alpha production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001745,,,,,,,,,,,,,,,,,,,,,,,,IL-1a release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific interleukin-1 alpha production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000164,cDNA library,,"Mixed population of cDNAs (complementaryDNA) made from mRNA from a defined source, usually a specific cell type. This term should be associated only to nucleic acid interactors not to their proteins product. For instance in 2h screening use living cells (MI:0349) as sample process.

ALT DEF (PRS):: a cDNA library is a collection of host cells, typically E.Coli cells but not exclusively. modified by transfer of plasmid DNA molecule used as vector containing a fragment or totality of cDNA molecule (the insert) .  cDNA library may have an array of role and applications.",false,,,http://purl.obolibrary.org/obo/OBI_0000731,,,,,,,,,,,,,,,,,"PRS: 22022008. class moved under population,
modification of definition and replacement of biomaterials in previous definition with 'material'
addition of has_role restriction",,"Mixed population of cDNAs (complementaryDNA) made from mRNA from a defined source, usually a specific cell type. This term should be associated only to nucleic acid interactors not to their proteins product. For instance in 2h screening use living cells (MI:0349) as sample process.

ALT DEF (PRS):: a cDNA library is a collection of host cells, typically E.Coli cells but not exclusively. modified by transfer of plasmid DNA molecule used as vector containing a fragment or totality of cDNA molecule (the insert) .  cDNA library may have an array of role and applications.",GROUP: PSI,,,,,,cDNA library,,PMID:6110205. collection of cDNA derived from mouse splenocytes.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,http://purl.obolibrary.org/obo/OBI_0000731,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000164,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0600064,,,cDNA library,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Philippe Rocca-Serra|PERSON: Luisa Montecchi,,
http://purl.obolibrary.org/obo/UBERON_0002813,right cerebral hemisphere,,A cerebral hemisphere that is in the right side of a brain.,false,,,http://purl.obolibrary.org/obo/CARO_0000055,,,,,,,,,,,,,,,,,,,A cerebral hemisphere that is in the right side of a brain.,,,,,,,right cerebral hemisphere,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UBERON:0002813,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uberon.owl,,,,,,,,,,,,,,,,,,,right cerebral hemisphere,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/UBERON_0002812,left cerebral hemisphere,,A cerebral hemisphere that is in the left side of a brain.,false,,,http://purl.obolibrary.org/obo/CARO_0000055,,,,,,,,,,,,,,,,,,,A cerebral hemisphere that is in the left side of a brain.,,,,,,,left cerebral hemisphere,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UBERON:0002812,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uberon.owl,,,,,,,,,,,,,,,,,,,left cerebral hemisphere,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000198,biological replicate role,biological replicate,a reference participant role realized by equivalent treatment of participants,false,,,http://purl.obolibrary.org/obo/OBI_0000220,,,,biological replicate,,,,,,,,,,,,,,,a reference participant role realized by equivalent treatment of participants,OBI,,,,,,biological replicate role,,A member of a dose-time group; a patient in a given arm of a trial,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000198,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,biological replicate role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0001694,in vivo assay measuring B cell epitope specific induction of hypersensitivity,hypersensitivity|in vivo assay,An efficacy of B cell epitope intervention experiment that detects a hypersensitivity response by monitoring skin reactions.,false,,,http://purl.obolibrary.org/obo/OBI_0001698,,,,,,,,,,,,,,,,,,,An efficacy of B cell epitope intervention experiment that detects a hypersensitivity response by monitoring skin reactions.,IEDB,,,,,,in vivo assay measuring B cell epitope specific induction of hypersensitivity,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001694,,,,,,,,,,,,,,,,,,,,,,,,hypersensitivity|in vivo assay,,,,,,,,,,,,,,,,,,,,,,in vivo assay measuring B cell epitope specific induction of hypersensitivity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_1110127,assay measuring binding of a B cell epitope:antibody complex,antibody binding|any method,An immune epitope assay that detects B cell epitope recognition.,false,,,http://purl.obolibrary.org/obo/OBI_1110128,,,,,,,,,,,,,,,,,,,An immune epitope assay that detects B cell epitope recognition.,IEDB,,,,,,assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110127,,,,,,,,,,,,,,,,,,,,,,,,antibody binding|any method,,,,,,,,,,,,,,,,,,,,,,assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000524,Varian VXR spectrometer,,A Varian NMR spectrometer.,false,,,http://purl.obolibrary.org/obo/OBI_0000611,,,,,,,,,,,,,,,,,NMR instrument,,A Varian NMR spectrometer.,WEB:<http://www.scs.uiuc.edu/NMR/instruments/vxr500.php>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400238,,,,,,Varian VXR spectrometer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000524,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Varian VXR spectrometer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0200011,logical transformation,,"A logical transformation is a data transformation that, for each (one dimensional) real number input x, outputs an approximation (found, e.g. with the Newton's method) to a solution y of the equation S(y)-x=0, where S denotes an s transformation.",false,,,http://purl.obolibrary.org/obo/OBI_0200169,,http://purl.obolibrary.org/obo/OBI_0200167,,,,,,,,,,,,,,,,,"A logical transformation is a data transformation that, for each (one dimensional) real number input x, outputs an approximation (found, e.g. with the Newton's method) to a solution y of the equation S(y)-x=0, where S denotes an s transformation.",WEB: http://flowcyt.sourceforge.net/gating/latest.pdf,,,,,,logical transformation,,This type of transformation is typically used in flow cytometry.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200011,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,logical transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Ryan Brinkman|Joseph Spliden|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0000662,error corrected data set,,A data set that is produced as the output of an error correction data transformation and consists of producing a data set which has had erroneous contributions from the input to the data transformation removed (corrected for).,false,,,http://purl.obolibrary.org/obo/IAO_0000100,,,,,,,,,,,,,,,,,,,A data set that is produced as the output of an error correction data transformation and consists of producing a data set which has had erroneous contributions from the input to the data transformation removed (corrected for).,,,,,,,error corrected data set,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000662,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,error corrected data set,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: James Malone|PERSON: Monnie McGee,,
http://purl.obolibrary.org/obo/OBI_0302891,trypsination,,trypsination is a protease cleavage which uses enzyme trypsin to act on proteins present in an input material entity,false,,,http://purl.obolibrary.org/obo/OBI_0600056,,,,,,,,,,,,,,,,,,,trypsination is a protease cleavage which uses enzyme trypsin to act on proteins present in an input material entity,OBI PA,,,,,,trypsination,,The use of mild trypsinization conditions in the detachment of endothelial cells to promote subsequent endothelialization on synthetic surfaces. Biomaterials. 2007 Sep;28(27):3928-35. PMID: 17570483,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302891,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,trypsination,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000057,allotransplantation,,is the transplantation of organs between members of the same species.,false,,,http://purl.obolibrary.org/obo/OBI_0000105,,,,,,,,,,,,,,,,,,,is the transplantation of organs between members of the same species.,OBI branch derived,,,,,,allotransplantation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000057,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,allotransplantation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_1110092,adjuvant role,adjuvent role,Adjuvant role is a role that inheres in a material entity and which is realized through a process of modifying a biological response.,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,adjuvent role,,,,,,,,,,,,,,,Adjuvant role is a role that inheres in a material entity and which is realized through a process of modifying a biological response.,IEDB,,,,,,adjuvant role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110092,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,adjuvant role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0600030,experimental disease induction,,a protocol application to induce a specific disease in an organism,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,could be defined class,,a protocol application to induce a specific disease in an organism,OBI branch derived,,,,,,experimental disease induction,,the injection of mice with LCM virus iv to establish an LCMV infection. Witholding food from animals to induce starvation syndrome.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600030,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,experimental disease induction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0001440,all pairs design,,A study design in which all specimens are compared to every other specimen.,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,A study design in which all specimens are compared to every other specimen.,MO_565 all_pairs,,,,,,all pairs design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001440,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,all pairs design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/SO_0000988,circular,,A quality of a nucleotide polymer that has no terminal nucleotide residues.,false,,,http://purl.obolibrary.org/obo/PATO_0001237,,,,,,,,,,,,,,,,,,,A quality of a nucleotide polymer that has no terminal nucleotide residues.,,,,,,,circular,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,SO:0000988,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/so.owl,,,,,,,,,,,,,,,,,,,circular,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001218,biological activity assay measuring epitope specific interleukin-8 production by T cells,IL-8 release|biological activity,A T cell epitope specific cytokine production assay that detects interleukin-8 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects interleukin-8 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific interleukin-8 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001218,,,,,,,,,,,,,,,,,,,,,,,,IL-8 release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific interleukin-8 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001084,vitrification apparatus,,A device that is used to effect the transition of a substance into a glass.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A device that is used to effect the transition of a substance into a glass.,http://en.wikipedia.org/wiki/Glass_transition,,,,,,vitrification apparatus,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000379,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001084,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,vitrification apparatus,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0002034,transcript leader sequencing,TL-seq,An RNA-seq assay combining enzymatic capture of m(7)G-capped mRNA 5' ends with high-throughput sequencing.,false,,,http://purl.obolibrary.org/obo/OBI_0001271,,,,TL-seq,,,,,,,,,,,,,,,An RNA-seq assay combining enzymatic capture of m(7)G-capped mRNA 5' ends with high-throughput sequencing.,pmid:23580730,,,,,Details see tracker: https://sourceforge.net/p/obi/obi-terms/725/,transcript leader sequencing,,pmid:23580730,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002034,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,transcript leader sequencing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Saccharomyces Genome Database (SGD),,,,,,,,"Janos Demeter, Chris Stoeckert",,
http://purl.obolibrary.org/obo/OBI_1000023,cell culture supernatant,,"Supernatant of a cell culture is a material entity which contains media, supplements, and secreted products of the cells and becomes the environment of cultivated cell.",false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,,,,,,,,,,,,,,,,"Supernatant of a cell culture is a material entity which contains media, supplements, and secreted products of the cells and becomes the environment of cultivated cell.",GROUP: IEDB,,http://purl.obolibrary.org/obo/OBI_0000079,,,,cell culture supernatant,,"solution containing RPMI, fetal calf sera, antibiotics, and monoclonal antibody UCHT1.
Isolation of proliferation factor of immature T-cell clone in concanavalin A-stimulated splenocyte culture supernatant. Immunology. 2003 Jun;109(2):209-16. PMID: 12757615",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1000023,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0600029,,,cell culture supernatant,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0400100,syringe pump,,Part of the fluidics system. A syringe pump can be used to inject the sample fluid and cells into the sheath fluid in the flow chamber. Syringe pumps are useful for creating stable flow rates.,false,,,http://purl.obolibrary.org/obo/OBI_0000967,,,,,,,,,,,,,,,,,,,Part of the fluidics system. A syringe pump can be used to inject the sample fluid and cells into the sheath fluid in the flow chamber. Syringe pumps are useful for creating stable flow rates.,"http://www.answers.com/topic/syringe, 2007-05-11",,,,,,syringe pump,,NE-1000 Single Syringe Pump,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000370|http://purl.obolibrary.org/obo/OBI_0000383,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,syringe pump,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:John Quinn,,
http://purl.obolibrary.org/obo/OBI_0001563,material processing service,,"A service in which a service provider makes physical changes to a specified input material entity with the objective of producing a new material entity form input materials, or modifying the input material entity, and returning this as output to the service consumer.",false,,,http://purl.obolibrary.org/obo/OBI_0001528,,,,,,,,,,,,,,,,,,,"A service in which a service provider makes physical changes to a specified input material entity with the objective of producing a new material entity form input materials, or modifying the input material entity, and returning this as output to the service consumer.",PERSON: Carlo Torniai,,,,,,material processing service,,A service for cell line creation. A service providing cel line immortalization.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001563,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,material processing service,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000094,,,,,,,,,,,,,,,,,,,,,,PERSON: Carlo Torniai|PERSON: Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_0200026,total intensity transformation single,,"A total intensity transformation single is a data transformation that takes as input an n-dimensional (real) vector and multiplies each component of this vector by a coefficient, where the coefficient is obtained by taking the sum of the input components or of a subset of these, multiplied by a constant of choice.",false,,,http://purl.obolibrary.org/obo/OBI_0200169,,http://purl.obolibrary.org/obo/OBI_0200167,,,,,,,,,,,,,,,"Note that if the word ""sum"" is replaced by the word ""mean"" in the definition, the resulting definition is equivalent.",,"A total intensity transformation single is a data transformation that takes as input an n-dimensional (real) vector and multiplies each component of this vector by a coefficient, where the coefficient is obtained by taking the sum of the input components or of a subset of these, multiplied by a constant of choice.",OTHER: Adjusted from MGED Ontology,,,,,,total intensity transformation single,,"This can be used as a simple normalization method for expression microarray assays. For example, each intensity from a one-channel microarray assay is multiplied by a constant so that the output mean intensity over the microarray equals a desired target T (the multiplicative constant in this case is the T/(mean intensity)).",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200026,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,total intensity transformation single,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Helen Parkinson|Melanie Courtot|Elisabetta Manduchi|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001909,conclusion based on data,,An information content entity that is inferred from data.,false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,,,,,,,,,,,,,,,,An information content entity that is inferred from data.,Group:2013 Philly Workshop group,,,,,"In the Philly 2013 workshop, we recognized the limitations of ""conclusion textual entity"", and we introduced this as more general. The need for the 'textual entity' term going forward is up for future debate. ",conclusion based on data,,"The conclusion that a gene is upregulated in a tissue sample based on the band intensity in a western blot. The conclusion that a patient has a infection based on measurement of an elevated body temperature and reported headache. The conclusion that there were problems in an investigation because data from PCR and microarray are conflicting.
The following are NOT conclusions based on data: data themselves; results from pure mathematics, e.g. ""13 is prime"".",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001909,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000338,http://purl.obolibrary.org/obo/IAO_0000027,,conclusion based on data,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Group:2013 Philly Workshop group,,
http://purl.obolibrary.org/obo/OBI_1110180,3H-thymidine assay measuring epitope specific proliferation of T cells,proliferation|3H-thymidine,A T cell epitope specific proliferation assay performed on cells in vitro that uses a tritiated thymidine incorporation assay.,false,,,http://purl.obolibrary.org/obo/OBI_0002071,,,,,,,,,,,,,,,,,,,A T cell epitope specific proliferation assay performed on cells in vitro that uses a tritiated thymidine incorporation assay.,IEDB,,,,,,3H-thymidine assay measuring epitope specific proliferation of T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110180,,,,,,,,,,,,,,,,,,,,,,,,proliferation|3H-thymidine,,,,,,,,,,,,,,,,,,,,,,3H-thymidine assay measuring epitope specific proliferation of T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000931,study intervention,,the part of the execution of an intervention design study which is varied between two or more subjects in the study,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,,,the part of the execution of an intervention design study which is varied between two or more subjects in the study,GROUP: OBI,,,,,,study intervention,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000931,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,study intervention,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001651,plasmon resonance assay measuring binding of a B cell epitope:antibody complex,qualitative binding|surface plasmon resonance (SPR),A B cell epitope qualitative binding to antibody assay that uses a surface plasmon resonance assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001703,,,,,,,,,,,,,,,,,,,A B cell epitope qualitative binding to antibody assay that uses a surface plasmon resonance assay.,IEDB,,,,,,plasmon resonance assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001651,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|surface plasmon resonance (SPR),,,,,,,,,,,,,,,,,,,,,,plasmon resonance assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001088,tandem mass spectrometer,,A mass spectrometer in which ions are subjected to two or more sequential stages of analysis (which may be separated spatially or temporally) according to the quotient mass/charge.,false,,,http://purl.obolibrary.org/obo/OBI_0000049,,,,,,,,,,,,,,,,,,,A mass spectrometer in which ions are subjected to two or more sequential stages of analysis (which may be separated spatially or temporally) according to the quotient mass/charge.,http://goldbook.iupac.org/T06250.html,,,,,,tandem mass spectrometer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001088,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,tandem mass spectrometer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001266,DNA methylation profiling by high throughput sequencing assay,,An assay in which the methylation state of DNA is determined and is compared between samples using sequencing based technology|Philippe Rocca-Serra,false,,,http://purl.obolibrary.org/obo/OBI_0000634,,,,,,,,,,,,,,,,,,,An assay in which the methylation state of DNA is determined and is compared between samples using sequencing based technology,EFO_0002761 methylation profiling by high throughput sequencing,,,,,,DNA methylation profiling by high throughput sequencing assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001266,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNA methylation profiling by high throughput sequencing assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Group: ArrayExpress production team, James Malone, Helen Parkinson",,
http://purl.obolibrary.org/obo/OBI_0000432,polyacrylamide gel,,a material entity resulting from the polymerization of acrylamide with TEMED in some buffer solution,false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,,,,,,,,,,,,,,,,a material entity resulting from the polymerization of acrylamide with TEMED in some buffer solution,GROUP: OBI Biomaterial Branch,,,,,,polyacrylamide gel,,Assessing CMT cell line stability by two dimensional polyacrylamide gel electrophoresis and mass spectrometry based proteome analysis. J Proteomics. 2008 Jul 21;71(2):160-7. PMID: 18617143,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_28619,,,,,,,,,,,,,,,,OBI:0000432,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0302890,,,polyacrylamide gel,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Jie Zheng|PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001810,biological activity assay measuring epitope specific granulysin release by T cells,granulysin release|biological activity,A T cell epitope specific cytotoxic T cell degranulation assay that detects granulysin release by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_0001269,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytotoxic T cell degranulation assay that detects granulysin release by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific granulysin release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001810,,,,,,,,,,,,,,,,,,,,,,,,granulysin release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific granulysin release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001609,intracellular cytokine staining assay measuring epitope specific interleukin-8 production by T cells,IL-8 release|ICS,An assay of epitope specific interleukin-8 production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001218,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-8 production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-8 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001609,,,,,,,,,,,,,,,,,,,,,,,,IL-8 release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-8 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001747,cytometric bead array assay measuring epitope specific interleukin-1 alpha production by T cells,IL-1a release|cytometric bead array,An assay of epitope specific interleukin-1 alpha production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001388,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-1 alpha production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific interleukin-1 alpha production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001747,,,,,,,,,,,,,,,,,,,,,,,,IL-1a release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific interleukin-1 alpha production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001999,3D structure determining assay of a T cell epitope:MHC:TCR complex,3D structure|any method,A T cell epitope recognition assay that uses a 3D structure determination of bound complex assay.,false,,,http://purl.obolibrary.org/obo/OBI_0600045|http://purl.obolibrary.org/obo/OBI_1110037,,,,,,,,,,,,,,,,,,,A T cell epitope recognition assay that uses a 3D structure determination of bound complex assay.,IEDB,,,,,,3D structure determining assay of a T cell epitope:MHC:TCR complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001999,,,,,,,,,,,,,,,,,,,,,,,,3D structure|any method,,,,,,,,,,,,,,,,,,,,,,3D structure determining assay of a T cell epitope:MHC:TCR complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001437,intracellular cytokine staining assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells,CXCL9/MIG release|ICS,An assay of epitope specific chemokine (C-X-C motif) ligand 9 production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001459,,,,,,,,,,,,,,,,,,,An assay of epitope specific chemokine (C-X-C motif) ligand 9 production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001437,,,,,,,,,,,,,,,,,,,,,,,,CXCL9/MIG release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/CHEBI_23528,cytochalasin,,,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,,,,,,,,cytochalasin,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:23528,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,cytochalasin,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200093,polynomial transformation,,"A polynomial transformation is a data transformation that is obtained through a polynomial, where a polynomial is a mathematical expression involving a sum of powers in one or more variables multiplied by coefficients (e.g. see http://mathworld.wolfram.com/Polynomial.html). The number of variables and the degree are properties of a polynomial. The degree of a polynomial is the highest power of its terms, where the terms of a polynomial are the individual summands with the coefficients omitted.",false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,"A polynomial transformation is a data transformation that is obtained through a polynomial, where a polynomial is a mathematical expression involving a sum of powers in one or more variables multiplied by coefficients (e.g. see http://mathworld.wolfram.com/Polynomial.html). The number of variables and the degree are properties of a polynomial. The degree of a polynomial is the highest power of its terms, where the terms of a polynomial are the individual summands with the coefficients omitted.",WEB: http://mathworld.wolfram.com/Polynomial.html,,,,,,polynomial transformation,,"a*x+b, with a non-zero, is a polynomial of degree one in one variable;  a*x^2+b*x+c, with a nonzero, is a polynomial of degree 2 in 1
variable; a*x*y+b*y+c, with a non-zero, is a polynomial of degree 2 in 2 variables (x and y); a_1*x_1+...+a_n*x_n+b, with at least one of the a_i's non-zero, is a polynomial of degree one in n variables",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200093,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,polynomial transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/PR_000003252,antithrombin-III,,A serpin that is a translation product of the human SERPINC1 gene or a 1:1 ortholog thereof.,false,,,http://purl.obolibrary.org/obo/PR_000000001,,,,,,,,,,,,,,,,,,,A serpin that is a translation product of the human SERPINC1 gene or a 1:1 ortholog thereof.,,,,,,,antithrombin-III,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PR:000003252,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pr.owl,,,,,,,,,,,,,,,,,,,antithrombin-III,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000451,normalized data set,,A data set that is produced as the output of a normalization data transformation.,false,,,http://purl.obolibrary.org/obo/IAO_0000100,,,,,,,,,,,,,,,,,,,A data set that is produced as the output of a normalization data transformation.,,,,,,,normalized data set,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000451,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,normalized data set,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot|PERSON: James Malone,,
http://purl.obolibrary.org/obo/OBI_0400051,Guava Personal Cell Analysis-96,Guava_PCA-96,"The Guava_Personal_Cell_Analysis-96 Systems is a flow_cytometer_analyser that includes a single 532 nm laser, and filters and PMTs to collect up to 2 fluorescent parameters. It includes a photodiode forward scatter collector. Guava cytometers use aspiration instead of fluid systems to transport cells within the machine. The PCA96 uses either tubes or 96 well plates to introduce specimen. The Guava PCA -96 cytometer is a small portable cytometer particularly useful for field measurement.",false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,Guava_PCA-96,,,,,,,,,,,,,,,"The Guava_Personal_Cell_Analysis-96 Systems is a flow_cytometer_analyser that includes a single 532 nm laser, and filters and PMTs to collect up to 2 fluorescent parameters. It includes a photodiode forward scatter collector. Guava cytometers use aspiration instead of fluid systems to transport cells within the machine. The PCA96 uses either tubes or 96 well plates to introduce specimen. The Guava PCA -96 cytometer is a small portable cytometer particularly useful for field measurement.",http://www.guavatechnologies.com/main/products/PCA-96new.cfm,,,,,,Guava Personal Cell Analysis-96,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400051,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Guava Personal Cell Analysis-96,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0000250,dye role,dye,A molecular label role which inheres in a material entity and which is realized in the process of detecting a molecular dye that imparts color to some material of interest. ,false,,,http://purl.obolibrary.org/obo/REO_0000171,,,,dye,,,,,,,,,,,,,,,A molecular label role which inheres in a material entity and which is realized in the process of detecting a molecular dye that imparts color to some material of interest. ,A substance used to color materials  www.answers.com/topic/dye  19feb09,,,,,,dye role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000250,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,dye role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0001753,ELISPOT assay measuring epitope specific granulocyte colony stimulating factor production by T cells,G-CSF release|ELISPOT,An assay of epitope specific granulocyte colony stimulating factor production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001600,,,,,,,,,,,,,,,,,,,An assay of epitope specific granulocyte colony stimulating factor production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific granulocyte colony stimulating factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001753,,,,,,,,,,,,,,,,,,,,,,,,G-CSF release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific granulocyte colony stimulating factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_1000029,phage display library,display library,a phage display library is a collection of materials in which a mixture of genes or gene fragments is expressed and can be individually selected and amplified.,false,,,http://purl.obolibrary.org/obo/OBI_0000731,,,,display library,,,,,,,,,,,,,"PRS: 22022008. class moved under population,
modification of definition and replacement of biomaterials in previous definition with 'material'
addition of has_role restriction",,a phage display library is a collection of materials in which a mixture of genes or gene fragments is expressed and can be individually selected and amplified.,WEB: http://www.immuneepitope.org/home.do,,,,,,phage display library,,PMID: 15905471.Nucleic Acids Res. 2005 May 19;33(9):e81.Oligonucleotide-assisted cleavage and ligation: a novel directional DNA cloning technology to capture cDNAs. Application in the construction of a human immune antibody phage-display library. [Phage display library encoding fragments of human antibodies. m-rna library encoding for 9-mer peptides],,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,http://purl.obolibrary.org/obo/OBI_0000731,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1000029,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0600064,,,phage display library,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters|PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/PR_000007928,glial cell line-derived neurotrophic factor,,A protein that is a translation product of the human GDNF gene or a 1:1 ortholog thereof.,false,,,http://purl.obolibrary.org/obo/PR_000000001,,,,,,,,,,,,,,,,,,,A protein that is a translation product of the human GDNF gene or a 1:1 ortholog thereof.,,,,,,,glial cell line-derived neurotrophic factor,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PR:000007928,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pr.owl,,,,,,,,,,,,,,,,,,,glial cell line-derived neurotrophic factor,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/NCBITaxon_5140,Neurospora,,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_716545,,,,,,,,,,,,,,,,,,,,,,,,,,Neurospora,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:5140,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Neurospora,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000457,manufacturing,,Manufacturing is a process with the intent to produce a processed material which will have a function for future use. A person or organization (having manufacturer role) is a participant in this process,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,,,,,,,,,,,,,,,,,,Manufacturing is a process with the intent to produce a processed material which will have a function for future use. A person or organization (having manufacturer role) is a participant in this process,GROUP: OBI PlanAndPlannedProcess Branch,,,,,This includes a single scientist making a processed material for personal use.|Manufacturing implies reproducibility and responsibility AR,manufacturing,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000040,http://purl.obolibrary.org/obo/OBI_0000047,,,OBI:0000457,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,manufacturing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot|PERSON: Jennifer Fostel|PERSON: Frank Gibson|PERSON: Bjoern Peters|PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000743,immune response assay,,an assay with the objective to determine information about an immune response,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,an assay with the objective to determine information about an immune response,,,,,,,immune response assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000743,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,immune response assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001990,assay measuring the half life of a MHC:ligand complex,half life|binding assay|min,A MHC binding constant determination assay measuring half life of binding.,false,,,http://purl.obolibrary.org/obo/OBI_0001553,,,,,,,,,,,,,,,,,,,A MHC binding constant determination assay measuring half life of binding.,IEDB,,,,,,assay measuring the half life of a MHC:ligand complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001990,,,,,,,,,,,,,,,,,,,,,,,,half life|binding assay|min,,,,,,,,,,,,,,,,,,,,,,assay measuring the half life of a MHC:ligand complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0600000,adding substance to cell culture,,is process in which a material substance is added to a cell culture,false,,,http://purl.obolibrary.org/obo/OBI_0000274,,http://purl.obolibrary.org/obo/OBI_0000434,,,,,,,,,,,,,,,,,is process in which a material substance is added to a cell culture,IEDB,,,,,"renamed from 'administering substance to cell culture', to reflect that administration is commonly used only for organisms",adding substance to cell culture,,adding fetal calf serum to a 96 well plate containing a cell culture derived from a blood sample of a patient,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100060,http://purl.obolibrary.org/obo/OBI_0100060,,,OBI:0600000,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,adding substance to cell culture,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/IAO_0000309,diagram,,A figure that expresses one or more propositions,false,,,http://purl.obolibrary.org/obo/IAO_0000308,,,,,,,,,,,,,,,,,,,A figure that expresses one or more propositions,,,,,,,diagram,,"A molecular structure ribbon cartoon showing helices, turns and sheets and their relations to each other in space.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000309,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,diagram,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0600060,DNA transfection,,"a transfection which relies on the use of physical, electrical and chemical phenomena to introduce DNA into a cell",false,,,http://purl.obolibrary.org/obo/OBI_0001152,,,,,,,,,,,,,,,,,,,"a transfection which relies on the use of physical, electrical and chemical phenomena to introduce DNA into a cell",OBI branch derived,,,,,,DNA transfection,,The use of electroporation to permeabilize a cell membrane in order to introduce a plasmid encoding for a labeled protein of interest,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600060,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNA transfection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Kevin Clancy,,
http://purl.obolibrary.org/obo/OBI_0001885,specimen repository organization,Specimen Repository,An organization that provides a service to store and distribute specimens,false,,,http://purl.obolibrary.org/obo/OBI_0000245,,,,,,,,,,,,,,,,,,,An organization that provides a service to store and distribute specimens,NIAID GSCID-BRC metadata working group,,,,,,specimen repository organization,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001885,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,specimen repository organization,,,,,,Specimen Repository,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0666667,nucleic acid extraction,,a material separation to recover the nucleic acid fraction of an input material,false,,,http://purl.obolibrary.org/obo/OBI_0302884,,,,,,,,,,,,,,,,,requested by Helen Parkinson for MO. Could be defined class,,a material separation to recover the nucleic acid fraction of an input material,OBI branch derived,,,,,,nucleic acid extraction,,Phenol / chlorophorm extraction disolvation of protein content folllowed by ethanol precipitation of the nucleic acid fraction over night in the fridge followed by centrifugation to obtain a nucleic acid pellet.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_33696,,,OBI:0666667,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,nucleic acid extraction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0302737,PCR-SSCP assay,polymerase chain reaction-single strand conformation polymorphism assay,"a PCR-SSCP assay is an assay that identifies DNA sequence variation (mutation, deletion, insertions) using gel electrophoresis technique and denaturating conditions on target DNA sequences amplified using polymerase chain reaction procedure.",false,,,http://purl.obolibrary.org/obo/OBI_0000435,,http://purl.obolibrary.org/obo/OBI_0000441,,polymerase chain reaction-single strand conformation polymorphism assay,,,,,,,,,,,,,,,"a PCR-SSCP assay is an assay that identifies DNA sequence variation (mutation, deletion, insertions) using gel electrophoresis technique and denaturating conditions on target DNA sequences amplified using polymerase chain reaction procedure.",PMID: 18219595.Mol Biotechnol. 2008 Feb;38(2):155-63.PCR-SSCP: a method for the molecular analysis of genetic diseases.,,,,,,PCR-SSCP assay,,PMID: 17334176.Hum Exp Toxicol. 2007 Jan;26(1):9-18.Is there a role for PCR-SSCP among the methods for missense mutation detection of TP53 gene?,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0600014|http://purl.obolibrary.org/obo/OBI_0000415,http://purl.obolibrary.org/obo/OBI_0000432,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000809,http://purl.obolibrary.org/obo/IAO_0000101|http://purl.obolibrary.org/obo/OBI_0001305,,,OBI:0302737,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PCR-SSCP assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0200195,proportional hazards model estimation,Cox proportional hazards model|Cox model,Proportional hazards model is a data transformation model to estimate the effects of different covariates influencing the times-to-failure of a system.,false,,,http://purl.obolibrary.org/obo/OBI_0200194,,http://purl.obolibrary.org/obo/OBI_0200083,,Cox proportional hazards model|Cox model,,,,,,,,,,,,,,,Proportional hazards model is a data transformation model to estimate the effects of different covariates influencing the times-to-failure of a system.,WEB: http://en.wikipedia.org/wiki/Cox_proportional_hazards_model,,,,,,proportional hazards model estimation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200195,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,proportional hazards model estimation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Tina Boussard|PERSON: James Malone,,
http://purl.obolibrary.org/obo/CLO_0009829,mortal cell line,,A cell line is able to support only a limited number of passages in vitro.,false,,,http://purl.obolibrary.org/obo/CLO_0000031,,,,,,,,,,,,,,,,,,,A cell line is able to support only a limited number of passages in vitro.,,,,,,,mortal cell line,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CLO_0000018,,,,,,,,,,,,,,,,,,,,,,,,,,,CLO:0009829,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/clo.owl,,,,,,,,,,,,,,,,,,,mortal cell line,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/CHEBI_59050,dimethyl sulfate,,The dimethyl ester of sulfuric acid.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,The dimethyl ester of sulfuric acid.,,,,,,,dimethyl sulfate,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:59050,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,dimethyl sulfate,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/CL_0000451,dendritic cell,,"A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative).",false,,,http://purl.obolibrary.org/obo/CL_0000000,,,,,,,,,,,,,,,,,,,"A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative).",,,,,,,dendritic cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CL:0000451,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/cl.owl,,,,,,,,,,,,,,,,,,,dendritic cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000568,piston-seal,,"The seal made by a piston in a diaphragm pump. The unique property of the reciprocating diaphragm pump is that the actuating piston does not come into direct contact with the mobile phase and thus, the demands on the piston-cylinder seal are not so great. The diaphragm has a relatively high surface area and thus, the movement of the diaphragm is relatively small and consequently the pump can be operated at a fairly high frequency. High frequency pumping results in a very significant reduction in pulse amplitude and, in addition, high frequency pulses are more readily damped by the column system. Nevertheless, it must be emphasized that diaphragm pumps are not pulseless.",false,,,http://purl.obolibrary.org/obo/OBI_0000601,,,,,,,,,,,,,,,,,,,"The seal made by a piston in a diaphragm pump. The unique property of the reciprocating diaphragm pump is that the actuating piston does not come into direct contact with the mobile phase and thus, the demands on the piston-cylinder seal are not so great. The diaphragm has a relatively high surface area and thus, the movement of the diaphragm is relatively small and consequently the pump can be operated at a fairly high frequency. High frequency pumping results in a very significant reduction in pulse amplitude and, in addition, high frequency pulses are more readily damped by the column system. Nevertheless, it must be emphasized that diaphragm pumps are not pulseless.",WEB:<http://www.chromatography-online.org/HPLC/Basic-HPLC/Pump/Diaphragm/rs15.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01116,,,,,,piston-seal,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000568,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,piston-seal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001031,array image creation,array image acquisition,An image creation process that generate an image from the array.,false,,,http://purl.obolibrary.org/obo/OBI_0001007,,,,array image acquisition,,,,,,,,,,,,,,,An image creation process that generate an image from the array.,MO_929: image_acquisition,,,,,,array image creation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0400147,http://purl.obolibrary.org/obo/IAO_0000101,,,OBI:0001031,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,array image creation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Jie Zheng,,
http://purl.obolibrary.org/obo/OBI_0001194,ELISPOT assay measuring epitope specific transforming growth factor-beta production by T cells,TGFb release|ELISPOT,An assay of epitope specific transforming growth factor-beta production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001264,,,,,,,,,,,,,,,,,,,An assay of epitope specific transforming growth factor-beta production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific transforming growth factor-beta production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001194,,,,,,,,,,,,,,,,,,,,,,,,TGFb release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific transforming growth factor-beta production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000598,ozone-induced chemiluminescence detector,,"Although there are many direct ozone chemiluminescent reactions with various gaseous molecules, the incorporation of a conversion step to convert various non-chemiluminescent analytes to a species capable of reacting with ozone to produce chemiluminescence broadens the horizon of this technique tremendously. The conversion of nearly all nitrogen- and sulfur-containing compounds to their respective chemiluminescent species for universal nitrogen and sulfur detection has made nitrogen/sulfur chemiluminescence detection the most widely used analytical methods based upon ozone-induced chemiluminescence. In addition to non-chromatographic applications, nitrogen/sulfur chemiluminescence detection has been adapted to various chromatographic techniques from gas chromatography to liquid and supercritical fluid chromatography as specialized element-specific detectors. The characteristics of these detectors are evaluated and compared to other element-selective detection techniques. The unique features of the chemiluminescence detectors have made them powerful tools in many diverse fields of analytical chemistry.",false,,,http://purl.obolibrary.org/obo/OBI_0000637,,,,,,,,,,,,,,,,,,,"Although there are many direct ozone chemiluminescent reactions with various gaseous molecules, the incorporation of a conversion step to convert various non-chemiluminescent analytes to a species capable of reacting with ozone to produce chemiluminescence broadens the horizon of this technique tremendously. The conversion of nearly all nitrogen- and sulfur-containing compounds to their respective chemiluminescent species for universal nitrogen and sulfur detection has made nitrogen/sulfur chemiluminescence detection the most widely used analytical methods based upon ozone-induced chemiluminescence. In addition to non-chromatographic applications, nitrogen/sulfur chemiluminescence detection has been adapted to various chromatographic techniques from gas chromatography to liquid and supercritical fluid chromatography as specialized element-specific detectors. The characteristics of these detectors are evaluated and compared to other element-selective detection techniques. The unique features of the chemiluminescence detectors have made them powerful tools in many diverse fields of analytical chemistry.",WEB:<http://sangerhinxtongbr.library.ingentaconnect.com/content/els/00219673/1999/00000842/00000001/art00177>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01088,,,,,,ozone-induced chemiluminescence detector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000598,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ozone-induced chemiluminescence detector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000418,measuring glucose concentration in blood serum,,An assay that determines the concentration of glucose molecules in a blood serum sample,false,,,http://purl.obolibrary.org/obo/OBI_0000443,,,,,,,,,,,,,,,,,,,An assay that determines the concentration of glucose molecules in a blood serum sample,,,,,,,measuring glucose concentration in blood serum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000418,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,measuring glucose concentration in blood serum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Bjoern Peters,,
http://purl.obolibrary.org/obo/GO_0097390,chemokine (C-X-C motif) ligand 12 production,,"The appearance of chemokine (C-X-C motif) ligand 12 (CXCL12) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0032602,,,,,,,,,,,,,,,,,,,"The appearance of chemokine (C-X-C motif) ligand 12 (CXCL12) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,chemokine (C-X-C motif) ligand 12 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0097390,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,chemokine (C-X-C motif) ligand 12 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0097392,chemokine (C-X-C motif) ligand 16 production,,"The appearance of chemokine (C-X-C motif) ligand 16 (CXCL16) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0032602,,,,,,,,,,,,,,,,,,,"The appearance of chemokine (C-X-C motif) ligand 16 (CXCL16) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,chemokine (C-X-C motif) ligand 16 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0097392,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,chemokine (C-X-C motif) ligand 16 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0097391,chemokine (C-X-C motif) ligand 13 production,,"The appearance of chemokine (C-X-C motif) ligand 13 (CXCL13) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0032602,,,,,,,,,,,,,,,,,,,"The appearance of chemokine (C-X-C motif) ligand 13 (CXCL13) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,chemokine (C-X-C motif) ligand 13 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0097391,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,chemokine (C-X-C motif) ligand 13 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001250,obsolete intracellular material detection by flow cytometry assay  of epitope specific cytotoxic T cell degranulation,T cell degranulation by intracellular staining,An intracellular material detection by flow cytometry assay  that measures epitope specific cytotoxic T cell degranulation,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,An intracellular material detection by flow cytometry assay  that measures epitope specific cytotoxic T cell degranulation,IEDB (QTT),,,,,,obsolete intracellular material detection by flow cytometry assay  of epitope specific cytotoxic T cell degranulation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000227,,,,,,,,,,,,,,,,,,OBI:0001250,,,,,,,,,,,,,,,,,,,,,,,,T cell degranulation by intracellular staining,,,,,,,,,,,,,,,,,,,,,,obsolete intracellular material detection by flow cytometry assay  of epitope specific cytotoxic T cell degranulation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",http://purl.obolibrary.org/obo/OBI_0000916,
http://purl.obolibrary.org/obo/OBI_0001631,electron microscopy imaging assay,,"An imaging assay in which an electrons are used to probe the density, shape and composition of an input material which are detected in an electron microscope and utilized to produce an image of the material.",false,,,http://purl.obolibrary.org/obo/OBI_0000185,,,,,,,,,,,,,,,,,,,"An imaging assay in which an electrons are used to probe the density, shape and composition of an input material which are detected in an electron microscope and utilized to produce an image of the material.",IEDB,,,,,,electron microscopy imaging assay,,Using gold labeled antibodies to stain a mouse brain slice and use electron microscopy to generate an image that shows the location of the antibodies within the tissue structure.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001631,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,electron microscopy imaging assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001766,detection of specific nucleic acids with complementary probes assay measuring epitope specific vascular endothelial growth factor production by T cells,VEGF release|RNA/DNA detection,An assay of epitope specific vascular endothelial growth factor production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001570,,,,,,,,,,,,,,,,,,,An assay of epitope specific vascular endothelial growth factor production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific vascular endothelial growth factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001766,,,,,,,,,,,,,,,,,,,,,,,,VEGF release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific vascular endothelial growth factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000055,software optimization objective,,Software_optimization is a software_testing_objective role describing a study designed to identify the best software or parameters of the software.,false,,,http://purl.obolibrary.org/obo/OBI_0000242,,,,,,,,,,,,,,,,,,,Software_optimization is a software_testing_objective role describing a study designed to identify the best software or parameters of the software.,,,,,,,software optimization objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000055,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,software optimization objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0001970,multiplexed sequencing library,DNA-barcoded sequencing library,"a multiplexed library is a material entity which is the output of a library preparation process that uses a ligation step to attach a unique multiplexing sequence identifier to a specific sample, then mixes several such tagged samples prior to the library amplification process proper. A multiplexed library allows the sequencing of several samples in one sequencing run.",false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,DNA-barcoded sequencing library,,,,,,,,,,,,,,,"a multiplexed library is a material entity which is the output of a library preparation process that uses a ligation step to attach a unique multiplexing sequence identifier to a specific sample, then mixes several such tagged samples prior to the library amplification process proper. A multiplexed library allows the sequencing of several samples in one sequencing run.",PRS for OBI,,,,,,multiplexed sequencing library,,"http://www.ncbi.nlm.nih.gov/pubmed/24997861

Nat Methods. 2014 Aug;11(8):834-40. doi: 10.1038/nmeth.3022. Epub 2014 Jul 6.
Accelerated chromatin biochemistry using DNA-barcoded nucleosome libraries.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001967,,,,,,,,,,,,,,,,OBI:0001970,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,multiplexed sequencing library,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001717,B cell epitope specific antibody-dependent cellular cytotoxicity,,antibody-dependent cellular cytotoxicity resulting from antibody binding to epitope,false,,,http://purl.obolibrary.org/obo/GO_0001788,,,,,,,,,,,,,,,,,Date: 2012-05-03; Spreadsheet: BcellAssays.xls; Worksheet: Especific template; Mapping: ebcell_specific_mappings.owl,,antibody-dependent cellular cytotoxicity resulting from antibody binding to epitope,IEDB (QTT),,,,,,B cell epitope specific antibody-dependent cellular cytotoxicity,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001717,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,B cell epitope specific antibody-dependent cellular cytotoxicity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0500006,parallel group design,independent measure design,"A parallel group design or independent measure design is a study design which uses unique experimental unit each experimental group, in other word no two individuals are shared between experimental groups, hence also known as parallel group design. Subjects of a treatment group receive a unique combination of independent variable values making up a treatment",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,independent measure design,,,,,,,,,,,,,,,"A parallel group design or independent measure design is a study design which uses unique experimental unit each experimental group, in other word no two individuals are shared between experimental groups, hence also known as parallel group design. Subjects of a treatment group receive a unique combination of independent variable values making up a treatment",http://www.holah.karoo.net/experimentaldesigns.htm,,,,,,parallel group design,,"PMID: 17408389-Purpose: Proliferative vitreoretinopathy (PVR) is the most important reason for blindness following retinal detachment. Presently, vitreous tamponades such as gas or silicone oil cannot contact the lower part of the retina. A heavier-than-water tamponade displaces the inflammatory and PVR-stimulating environment from the inferior area of the retina. The Heavy Silicone Oil versus Standard Silicone Oil Study (HSO Study) is designed to answer the question of whether a heavier-than-water tamponade improves the prognosis of eyes with PVR of the lower retina. Methods: The HSO Study is a multicentre, randomized, prospective controlled clinical trial comparing two endotamponades within a two-arm parallel group design. Patients with inferiorly and posteriorly located PVR are randomized to either heavy silicone oil or standard silicone oil as a tamponading agent. Three hundred and fifty consecutive patients are recruited per group. After intraoperative re-attachment, patients are randomized to either standard silicone oil (1000 cSt or 5000 cSt) or Densiron((R)) as a tamponading agent. The main endpoint criteria are complete retinal attachment at 12 months and change of visual acuity (VA) 12 months postoperatively compared with the preoperative VA. Secondary endpoints include complete retinal attachment before endotamponade removal, quality of life analysis and the number of retina affecting re-operation within 1 year of follow-up. Results: The design and early recruitment phase of the study are described. Conclusions: The results of this study will uncover whether or not heavy silicone oil improves the prognosis of eyes with PVR.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500006,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,parallel group design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001270,cell culture analyte detection bioassay measuring epitope specific transforming growth factor-beta production by T cells,TGFb release|bioassay,An assay of epitope specific transforming growth factor-beta production by T cells that uses a cell culture analyte detection bioassay.,false,,,http://purl.obolibrary.org/obo/OBI_0001264,,,,,,,,,,,,,,,,,,,An assay of epitope specific transforming growth factor-beta production by T cells that uses a cell culture analyte detection bioassay.,IEDB,,,,,,cell culture analyte detection bioassay measuring epitope specific transforming growth factor-beta production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001270,,,,,,,,,,,,,,,,,,,,,,,,TGFb release|bioassay,,,,,,,,,,,,,,,,,,,,,,cell culture analyte detection bioassay measuring epitope specific transforming growth factor-beta production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0200153,number of variables,,"The number of variables is a feature of any function (including polynomial functions) with domain contained in an n-dimensional vector space and is defined as n, the dimension of such space.",false,,,http://purl.obolibrary.org/obo/OBI_0200140,,,,,,,,,,,,,,,,,,,"The number of variables is a feature of any function (including polynomial functions) with domain contained in an n-dimensional vector space and is defined as n, the dimension of such space.",PERSON: Elisabetta Manduchi,,,,,,number of variables,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200153,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,number of variables,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/UO_0000002,mass unit,,A unit which is a standard measure of the amount of matter/energy of a physical object.,false,,,http://purl.obolibrary.org/obo/IAO_0000003,,,,,,,,,,,,,,,,,,,A unit which is a standard measure of the amount of matter/energy of a physical object.,,,,,,,mass unit,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UO:0000002,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uo.owl,,,,,,,,,,,,,,,,,,,mass unit,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/UO_0000001,length unit,,A unit which is a standard measure of the distance between two points.,false,,,http://purl.obolibrary.org/obo/IAO_0000003,,,,,,,,,,,,,,,,,,,A unit which is a standard measure of the distance between two points.,,,,,,,length unit,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UO:0000001,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uo.owl,,,,,,,,,,,,,,,,,,,length unit,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/UO_0000005,temperature unit,,A unit which is a standard measure of the average kinetic energy of the particles in a sample of matter.,false,,,http://purl.obolibrary.org/obo/IAO_0000003,,,,,,,,,,,,,,,,,,,A unit which is a standard measure of the average kinetic energy of the particles in a sample of matter.,,,,,,,temperature unit,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UO:0000005,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uo.owl,,,,,,,,,,,,,,,,,,,temperature unit,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/UO_0000003,time unit,,A unit which is a standard measure of the dimension in which events occur in sequence.,false,,,http://purl.obolibrary.org/obo/IAO_0000003,,,,,,,,,,,,,,,,,,,A unit which is a standard measure of the dimension in which events occur in sequence.,,,,,,,time unit,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UO:0000003,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uo.owl,,,,,,,,,,,,,,,,,,,time unit,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/UO_0000006,substance unit,,A unit which is a standardised quantity of an element or compound with uniform composition.,false,,,http://purl.obolibrary.org/obo/IAO_0000003,,,,,,,,,,,,,,,,,,,A unit which is a standardised quantity of an element or compound with uniform composition.,,,,,,,substance unit,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UO:0000006,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uo.owl,,,,,,,,,,,,,,,,,,,substance unit,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001828,cytometric bead array assay measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells,CCL1/TCA-3 release|cytometric bead array,An assay of epitope specific chemokine (C-C motif) ligand 1 production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001276,,,,,,,,,,,,,,,,,,,An assay of epitope specific chemokine (C-C motif) ligand 1 production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001828,,,,,,,,,,,,,,,,,,,,,,,,CCL1/TCA-3 release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000029,centrifuge pellet role,,pellet role is a role which inheres in a material entity and is realized by a material separation process using gravitational force generated by a centrifuge in which the material bearing the pellet role is the heavier or heaviest component of the output material..,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,9Mar09 after discussion with process branch changed definition to include use of centrifuge;,,pellet role is a role which inheres in a material entity and is realized by a material separation process using gravitational force generated by a centrifuge in which the material bearing the pellet role is the heavier or heaviest component of the output material..,OBI,,,,,,centrifuge pellet role,,Definition of pellet :the material concentrated at the bottom of a centrifuge tube after centrifugation. http://www.everythingbio.com/glos/definition.php?word=pellet,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000029,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,centrifuge pellet role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP:  Role branch,,
http://purl.obolibrary.org/obo/OBI_0001883,Bioinformatics Resource Center contact person,Bioinformatics Resource Center Contact Name,A person who is the contact representative of a Bioinformatics Resource Center,false,,,http://purl.obolibrary.org/obo/NCBITaxon_9606,,,,,,,,,,,,,,,,,,,A person who is the contact representative of a Bioinformatics Resource Center,NIAID GSCID-BRC metadata working group,,,,,,Bioinformatics Resource Center contact person,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001883,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bioinformatics Resource Center contact person,,,,,,Bioinformatics Resource Center Contact Name,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0600005,collecting specimen from organism,,a process with the objective to obtain a material entity that was part of an organism for potential future use in an investigation,false,,,http://purl.obolibrary.org/obo/OBI_0000659,,http://purl.obolibrary.org/obo/OBI_0000684,,,,,,,,,,,,,,,,,a process with the objective to obtain a material entity that was part of an organism for potential future use in an investigation,IEDB,,,,,,collecting specimen from organism,,"taking a sputum sample from a cancer patient, taking the spleen from a killed mouse, collecting a urine sample from a patient",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100026,http://purl.obolibrary.org/obo/OBI_0100051,,,OBI:0600005,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,collecting specimen from organism,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0200078,descriptive statistical calculation objective,,"A descriptive statistical calculation objective is a data transformation objective which concerns any calculation intended to describe a feature of a data set, for example, its center or its variability.",false,,,http://purl.obolibrary.org/obo/OBI_0200166,,,,,,,,,,,,,,,,,,,"A descriptive statistical calculation objective is a data transformation objective which concerns any calculation intended to describe a feature of a data set, for example, its center or its variability.",PERSON: Elisabetta Manduchi|PERSON: James Malone|PERSON: Melanie Courtot|PERSON: Monnie McGee,,,,,,descriptive statistical calculation objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200078,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,descriptive statistical calculation objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Monnie McGee|Melanie Courtot|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/GO_0032628,interleukin-24 production,,"The appearance of interleukin-24 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-24 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-24 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032628,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-24 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032624,interleukin-20 production,,"The appearance of interleukin-20 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-20 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-20 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032624,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-20 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032627,interleukin-23 production,,"The appearance of interleukin-23 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-23 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-23 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032627,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-23 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032626,interleukin-22 production,,"The appearance of interleukin-22 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-22 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-22 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032626,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-22 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032620,interleukin-17 production,,"The appearance of any member of the interleukin-17 family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of any member of the interleukin-17 family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-17 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032620,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-17 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032629,interleukin-25 production,,"The appearance of interleukin-25 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-25 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-25 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032629,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-25 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032622,interleukin-19 production,,"The appearance of interleukin-19 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-19 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-19 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032622,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-19 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032625,interleukin-21 production,,"The appearance of interleukin-21 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-21 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-21 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032625,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-21 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032621,interleukin-18 production,,"The appearance of interleukin-18 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-18 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-18 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032621,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-18 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032623,interleukin-2 production,,"The appearance of interleukin-2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-2 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032623,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-2 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001189,epitope protection experiment based on survival,host survival after challenge,an epitope protection experiment that determines the success of the epitope intervention based on increased survival of the host. ,false,,,http://purl.obolibrary.org/obo/OBI_0001184,,,,,,,,,,,,,,,,,,,an epitope protection experiment that determines the success of the epitope intervention based on increased survival of the host. ,,,,,,,epitope protection experiment based on survival,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000699,,,,,,,,,,,,,,,,OBI:0001189,,,,,,,,,,,,,,,,,,,,,,,,host survival after challenge,,,,,,,,,,,,,,,,,,,,,,epitope protection experiment based on survival,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000609,glass column,,A glass column is a chromatography column made out of glass that is usually used for larger scale and preparative liquid chromatography separations.,false,,,http://purl.obolibrary.org/obo/OBI_0000038,,,,,,,,,,,,,,,,,,,A glass column is a chromatography column made out of glass that is usually used for larger scale and preparative liquid chromatography separations.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01101,,,,,,glass column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000609,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,glass column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000973,sequence data,,"A measurement datum that representing the primary structure of a macromolecule(it's sequence) sometimes associated with an indicator of confidence of that measurement.
",false,,,http://purl.obolibrary.org/obo/IAO_0000109,,,,,,,,,,,,,,,,,,,"A measurement datum that representing the primary structure of a macromolecule(it's sequence) sometimes associated with an indicator of confidence of that measurement.
",GROUP: OBI,,,,,,sequence data,,example of usage: the representation of a nucleotide sequence in FASTA format used for a sequence similarity search.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000973,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sequence data,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0400157,oil bath,,An oil bath is a temperature control bath in which oil acts as contact medium for the temperature transfer (from heating or cooling elements to the sample).,false,,,http://purl.obolibrary.org/obo/OBI_0400120,,,,,,,,,,,,,,,,,,,An oil bath is a temperature control bath in which oil acts as contact medium for the temperature transfer (from heating or cooling elements to the sample).,PERSON: Daniel Schober,,,,,,oil bath,,An oil bath was used to allow for fast reaction of two chemical compounds during a 2 hour period.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400157,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,oil bath,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_1110031,EL-4 cell line,,A cell line derived from mouse (C57BL/6N) lymphoma cells.,false,,,http://purl.obolibrary.org/obo/CLO_0009828,,,,,,,,,,,,,,,,,,,A cell line derived from mouse (C57BL/6N) lymphoma cells.,IEDB|http://www.biotech.ist.unige.it/cldb/cl1160.html,,,,,,EL-4 cell line,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110031,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,EL-4 cell line,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001286,RNAi profiling by array design,,"A study design in which experiment double stranded RNA is synthesized with a sequence complementary to a gene(s) of interest and introduced into a cell or organism, where it is recognized as exogenous genetic material and activates the RNAi pathway resulting in knockdown of the transcripts and providing a means to study downstream changes in gene expression.",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A study design in which experiment double stranded RNA is synthesized with a sequence complementary to a gene(s) of interest and introduced into a cell or organism, where it is recognized as exogenous genetic material and activates the RNAi pathway resulting in knockdown of the transcripts and providing a means to study downstream changes in gene expression.",Group: ArrayExpress production team,,,,,,RNAi profiling by array design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000131,,,,,,,,,,,,,,,,OBI:0001286,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,RNAi profiling by array design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0400020,cell sorter collection tube,,Part of the fluidics subsystem. The collection tube is a vessel for capturing cells of interest that have been identified by a sorter. The collection tube is the end location of sorted cells.,false,,,http://purl.obolibrary.org/obo/OBI_0000836,,,,,,,,,,,,,,,,,,,Part of the fluidics subsystem. The collection tube is a vessel for capturing cells of interest that have been identified by a sorter. The collection tube is the end location of sorted cells.,"Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253",,,,,,cell sorter collection tube,,LSR2 collection tube,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400020,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cell sorter collection tube,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0200041,k-means clustering,,"A k-means clustering is a data transformation which achieves a class discovery or partitioning objective, which takes as input a collection of objects (represented as points in multidimensional space) and which partitions them into a specified number k of clusters. The algorithm attempts to find the centers of natural clusters in the data. The most common form of the algorithm starts by partitioning the input points into k initial sets, either at random or using some heuristic data. It then calculates the mean point, or centroid, of each set. It constructs a new partition by associating each point with the closest centroid. Then the centroids are recalculated for the new clusters, and the algorithm repeated by alternate applications of these two steps until convergence, which is obtained when the points no longer switch clusters (or alternatively centroids are no longer changed).",false,,,http://purl.obolibrary.org/obo/OBI_0200171|http://purl.obolibrary.org/obo/OBI_0200175,,http://purl.obolibrary.org/obo/OBI_0200172,,,,,,,,,,,,,,,,,"A k-means clustering is a data transformation which achieves a class discovery or partitioning objective, which takes as input a collection of objects (represented as points in multidimensional space) and which partitions them into a specified number k of clusters. The algorithm attempts to find the centers of natural clusters in the data. The most common form of the algorithm starts by partitioning the input points into k initial sets, either at random or using some heuristic data. It then calculates the mean point, or centroid, of each set. It constructs a new partition by associating each point with the closest centroid. Then the centroids are recalculated for the new clusters, and the algorithm repeated by alternate applications of these two steps until convergence, which is obtained when the points no longer switch clusters (or alternatively centroids are no longer changed).",WEB: http://en.wikipedia.org/wiki/K-means,,,,,,k-means clustering,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200041,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,k-means clustering,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Philippe Rocca-Serra|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/IAO_0000307,table of abbreviations,,A table where the constituent texts are abbreviations and their expansions,false,,,http://purl.obolibrary.org/obo/IAO_0000306,,,,,,,,,,,,,,,,,,,A table where the constituent texts are abbreviations and their expansions,,,,,,,table of abbreviations,,"IAO  information artifact ontology
OBI  ontology of biomedical investiations
GO   gene ontology",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000307,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,table of abbreviations,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0001974,Ion 314 Chip v2,Ion 314 Chip|Ion PGM 314 Chip|Ion PGM 314 Chip v2,"An ion semiconductor chip manufactured by Life Technologies which detects polymerase-driven base incorporation to translate into digital form. The 314 chip is compatible with the Ion Torrent PGM and has a run time of:

2.3 hours for 200 bp reads with an output of 30-50 Mb,
3.7 hours for 400 bp reads with an output of 60-100 Mb.",false,,,http://purl.obolibrary.org/obo/OBI_0001973,,,,Ion 314 Chip|Ion PGM 314 Chip|Ion PGM 314 Chip v2,,,,,,,,,,,,,,,"An ion semiconductor chip manufactured by Life Technologies which detects polymerase-driven base incorporation to translate into digital form. The 314 chip is compatible with the Ion Torrent PGM and has a run time of:

2.3 hours for 200 bp reads with an output of 30-50 Mb,
3.7 hours for 400 bp reads with an output of 60-100 Mb.",http://www.lifetechnologies.com/us/en/home/life-science/sequencing/next-generation-sequencing/ion-torrent-next-generation-sequencing-workflow/ion-torrent-next-generation-sequencing-run-sequence/ion-pgm-ion-proton-system-chips.html,,,,,"Issue Tracker #766
https://sourceforge.net/p/obi/obi-terms/766/",Ion 314 Chip v2,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001974,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Ion 314 Chip v2,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Sagar Jain,,
http://purl.obolibrary.org/obo/GO_0005694,chromosome,,A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.,false,,,http://purl.obolibrary.org/obo/GO_0005575,,,,,,,,,,,,,,,,,,,A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.,,,,,,,chromosome,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0005694,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,chromosome,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001825,epitope specific chemokine (C-C motif) ligand 19 production by T cells,,A process of chemokine (C-C motif) ligand 19 production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0097388|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,Date: 2012-11-16; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mappings: MMExpressionsTcell.txt,,A process of chemokine (C-C motif) ligand 19 production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific chemokine (C-C motif) ligand 19 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001825,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific chemokine (C-C motif) ligand 19 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000614,guard column,,Guard columns are installed between the injection valve and the analytical or preparative column and here will remove contaminants and prolong the lifetime of the columns.,false,,,http://purl.obolibrary.org/obo/OBI_0000048,,,,,,,,,,,,,,,,,chromatography device,,Guard columns are installed between the injection valve and the analytical or preparative column and here will remove contaminants and prolong the lifetime of the columns.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01111,,,,,,guard column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000614,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,guard column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0500014,factorial design,,"factorial design is_a study design which is used to evaluate two or more factors simultaneously. The treatments are combinations of levels of the factors. The advantages of factorial designs over one-factor-at-a-time experiments is that they are more efficient and they allow interactions to be detected. In statistics, a factorial design experiment is an experiment whose design consists of two or more factors, each with discrete possible values or levels, and whose experimental units take on all possible combinations of these levels across all such factors. Such an experiment allows studying the effect of each factor on the response variable, as well as the effects of interactions between factors on the response variable.",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"factorial design is_a study design which is used to evaluate two or more factors simultaneously. The treatments are combinations of levels of the factors. The advantages of factorial designs over one-factor-at-a-time experiments is that they are more efficient and they allow interactions to be detected. In statistics, a factorial design experiment is an experiment whose design consists of two or more factors, each with discrete possible values or levels, and whose experimental units take on all possible combinations of these levels across all such factors. Such an experiment allows studying the effect of each factor on the response variable, as well as the effects of interactions between factors on the response variable.",http://www.stats.gla.ac.uk/steps/glossary/anova.html#facdes And from wikipedia (01/03/2007): http://en.wikipedia.org/wiki/Factorial_experiment),,,,,,factorial design,,"PMID: 17582121-Our objective was to examine the effects of dietary cation-anion difference (DCAD) with different concentrations of dietary crude protein (CP) on performance and acid-base status in early lactation cows. Six lactating Holstein cows averaging 44 d in milk were used in a 6 x 6 Latin square design with a 2 x 3 factorial arrangement of treatments: DCAD of -3, 22, or 47 milliequivalents (Na + K - Cl - S)/100 g of dry matter (DM), and 16 or 19% CP on a DM basis. Linear increases with DCAD occurred in DM intake, milk fat percentage, 4% fat-corrected milk production, milk true protein, milk lactose, and milk solids-not-fat. Milk production itself was unaffected by DCAD. Jugular venous blood pH, base excess and HCO3(-) concentration, and urine pH increased, but jugular venous blood Cl- concentration, urine titratable acidity, and net acid excretion decreased linearly with increasing DCAD. An elevated ratio of coccygeal venous plasma essential AA to nonessential AA with increasing DCAD indicated that N metabolism in the rumen was affected, probably resulting in more microbial protein flowing to the small intestine. Cows fed 16% CP had lower urea N in milk than cows fed 19% CP; the same was true for urea N in coccygeal venous plasma and urine. Dry matter intake, milk production, milk composition, and acid-base status did not differ between the 16 and 19% CP treatments. It was concluded that DCAD affected DM intake and performance of dairy cows in early lactation. Feeding 16% dietary CP to cows in early lactation, compared with 19% CP, maintained lactation performance while reducing urea N excretion in milk and urine.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500014,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,factorial design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001249,epitope specific T cell tolerance induction,,A process of T cell tolerance induction resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0002517|http://purl.obolibrary.org/obo/OBI_0001201,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of T cell tolerance induction resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific T cell tolerance induction,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001249,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific T cell tolerance induction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000895,total RNA extract,,A RNA extract that is the output of an extraction process in which total celluar and organelle RNA molecules are isolated from a specimen.,false,,,http://purl.obolibrary.org/obo/OBI_0000880,,,,,,,,,,,,,,,,,,,A RNA extract that is the output of an extraction process in which total celluar and organelle RNA molecules are isolated from a specimen.,UPenn Group,,,,,,total RNA extract,,Extraction of total RNA from cells with Qiagen mini RNeasy kit.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000895,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000855,,,total RNA extract,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Chris Stoeckert|PERSON: Jie Zheng,,
http://purl.obolibrary.org/obo/OBI_1110129,biological activity assay measuring epitope specific cytokine production by T cells,cytokine release|biological activity,A T cell epitope dependent biological activity assay that detects cytokine production.,false,,,http://purl.obolibrary.org/obo/OBI_0002055,,,,,,,,,,,,,,,,,,,A T cell epitope dependent biological activity assay that detects cytokine production.,IEDB,,,,,,biological activity assay measuring epitope specific cytokine production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110129,,,,,,,,,,,,,,,,,,,,,,,,cytokine release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific cytokine production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/IAO_0000109,measurement datum,,A measurement datum is an information content entity that is a recording of the output of a measurement such as produced by a device.,false,,,http://purl.obolibrary.org/obo/IAO_0000027,,,,,,,,,,,,,,,,,,,A measurement datum is an information content entity that is a recording of the output of a measurement such as produced by a device.,group:OBI|OBI_0000305,,,,,2/2/2009 is_specified_output of some assay?,measurement datum,,"Examples of measurement data are the recoding of the weight of a mouse as {40,mass,""grams""}, the recording of an observation of the behavior of the mouse {,process,""agitated""}, the recording of the expression level of a gene as measured through the process of microarray experiment {3.4,luminosity,}.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001933,,,,,,,,,IAO:0000109,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,measurement datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0001457,cytometric bead array assay measuring epitope specific interleukin-8 production by T cells,IL-8 release|cytometric bead array,An assay of epitope specific interleukin-8 production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001218,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-8 production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific interleukin-8 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001457,,,,,,,,,,,,,,,,,,,,,,,,IL-8 release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific interleukin-8 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/IAO_0000573,line graph,line chart,"A line graph is a type of graph created by connecting a series of data
points together with a line.",false,,,http://purl.obolibrary.org/obo/IAO_0000038,,,,line chart,,,,,,,,,,,,,,,"A line graph is a type of graph created by connecting a series of data
points together with a line.",GROUP:OBI|WEB: http://en.wikipedia.org/wiki/Line_chart,,,,,,line graph,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000573,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,line graph,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Chris Stoeckert|PERSON:Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0001087,lyophilizer,,A device that is used to freeze dry material.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A device that is used to freeze dry material.,http://en.wikipedia.org/wiki/Freeze_drying,,,,,,lyophilizer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000379|http://purl.obolibrary.org/obo/OBI_0000375,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001087,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,lyophilizer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_1110201,allergen,,A material entity bearing the disposition to cause an allergic reaction,false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,A material entity bearing the disposition to cause an allergic reaction,IEDB,,,,,,allergen,,Birch pollen is an allergen,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110201,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,allergen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001797,ELISPOT assay measuring epitope specific interleukin-9 production by T cells,IL-9 release|ELISPOT,An assay of epitope specific interleukin-9 production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001253,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-9 production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific interleukin-9 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001797,,,,,,,,,,,,,,,,,,,,,,,,IL-9 release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific interleukin-9 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/CARO_0001008,gross anatomical part,,"Anatomical structure that is part of a multicellular organism and is at the gross anatomical level, e.g. above the level of a cell.  Included are portions of organism substances such as blood, multi-cell-part structures such as axon tracts, acellular anatomical structures such as hair, and organism subdivisions such as head. Excluded is the whole organism and more granular parts of the organism, such as atoms, molecules, macromolecular complexes and cells.",false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,"Anatomical structure that is part of a multicellular organism and is at the gross anatomical level, e.g. above the level of a cell.  Included are portions of organism substances such as blood, multi-cell-part structures such as axon tracts, acellular anatomical structures such as hair, and organism subdivisions such as head. Excluded is the whole organism and more granular parts of the organism, such as atoms, molecules, macromolecular complexes and cells.",,,,,,,gross anatomical part,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CARO:0001008,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/caro.owl,,,,,,,,,,,,,,,,,,,gross anatomical part,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001916,DNA replication identification objective,,"A molecular feature identification objective that aims to examine charateristics of DNA replication, such as replication time.",false,,,http://purl.obolibrary.org/obo/OBI_0000131,,,,,,,,,,,,,,,,,,,"A molecular feature identification objective that aims to examine charateristics of DNA replication, such as replication time.",Group: Penn Group,,,,,,DNA replication identification objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001916,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNA replication identification objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0400074,mixed argon-krypton gas laser,,A mixed argon krypton gas laser is an ion laser in which the lasing medium is a mixture of argon and krypton. A mixed argon-krypton laser can by used to irradiate cells in a flow cytometer.,false,,,http://purl.obolibrary.org/obo/OBI_0400060,,,,,,,,,,,,,,,,,,,A mixed argon krypton gas laser is an ion laser in which the lasing medium is a mixture of argon and krypton. A mixed argon-krypton laser can by used to irradiate cells in a flow cytometer.,http://www.eio.com/repairfaq/sam/laserarg.htm,,,,,,mixed argon-krypton gas laser,,argon-krypton laser in a cytometer,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400074,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,mixed argon-krypton gas laser,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0000634,DNA methylation profiling assay,DNA methylation profiling,an assay which aims to provide information about state of methylation of DNA molecules using genomic DNA collected from a material entity using a range of techniques and instrument such as DNA sequencers and often relying on treatment with bisulfites to ensure cytosine conversion.,false,,,http://purl.obolibrary.org/obo/OBI_0002020|http://purl.obolibrary.org/obo/OBI_0000443,,http://purl.obolibrary.org/obo/OBI_0001234,,,,,,,,,,,,,,,,,an assay which aims to provide information about state of methylation of DNA molecules using genomic DNA collected from a material entity using a range of techniques and instrument such as DNA sequencers and often relying on treatment with bisulfites to ensure cytosine conversion.,OBI branch derived,,,,,,DNA methylation profiling assay,,"Genome-wide, high-resolution DNA methylation profiling using bisulfite-mediated cytosine conversion.  Reinders J, Delucinge Vivier C, Theiler G, Chollet D, Descombes P, Paszkowski J. 
Genome Res. 2008 Mar;18(3):469-76. Epub 2008 Jan 24.  PMID: 18218979",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000634,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNA methylation profiling,DNA methylation profiling assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000523,magic angle spinning rotor,MAS rotor,A rotor device that holds the NMR sample and enables the adjustment of the orientation of the rotation axis for a sample in a NMR instrument in the magic angle.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,MAS rotor,,,,,,,,,,,,,NMR instrument,,A rotor device that holds the NMR sample and enables the adjustment of the orientation of the rotation axis for a sample in a NMR instrument in the magic angle.,WEB:<http://www.freepatentsonline.com/4352066.html>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400130,,,,,,magic angle spinning rotor,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000566,OBI:0000523,http://purl.obolibrary.org/obo/OBI_0000566,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,magic angle spinning rotor,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0200119,median calculation,,"A median calculation is a  descriptive statistics calculation in which the midpoint of the data set (the 0.5 quantile) is calculated.  First, the observations are sorted in increasing order.  For an odd number of observations, the median is the middle value of the sorted data.  For an even number of observations, the median is the average of the two middle values.",false,,,http://purl.obolibrary.org/obo/OBI_0200184|http://purl.obolibrary.org/obo/OBI_0200181,,http://purl.obolibrary.org/obo/OBI_0200078,,,,,,,,,,,,,,,From Monnie's file comments - need to add center_calculation role but it doesn't exist yet - (editor note added by James Jan 2008),,"A median calculation is a  descriptive statistics calculation in which the midpoint of the data set (the 0.5 quantile) is calculated.  First, the observations are sorted in increasing order.  For an odd number of observations, the median is the middle value of the sorted data.  For an even number of observations, the median is the average of the two middle values.",PERSON: James Malone|PERSON: Monnie McGee,,,,,,median calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200119,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,median calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Monnie McGee,,
http://purl.obolibrary.org/obo/OBI_0100065,synthetic peptide,,a synthetic peptide is an material entity which is artificially engineered and results from the synthesis of a chain of amino acids which may also be found in natural protein and be identical in sequence to a protein fragment,false,,,http://purl.obolibrary.org/obo/CHEBI_16670|http://purl.obolibrary.org/obo/OBI_0000047,,,,,,,,,,,,,,,,,"PRS:22-02-2008: a chebi entity which has output role in a synthesis protocol application|original term: protein fragment split into synthetic polypeptide and fragment derived from protein
DS: Is this synthetic an oxymoron to the biomaterial?",,a synthetic peptide is an material entity which is artificially engineered and results from the synthesis of a chain of amino acids which may also be found in natural protein and be identical in sequence to a protein fragment,IEDB,,,,,"changed from synthetic polypeptide to peptide, to get rid of the restriction of having more than 10 amino acids (required by Chebi).",synthetic peptide,,the synthesized peptide SIINFEKL which also occurs in hen-egg lysozyme,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0100065,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,synthetic peptide,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001501,fluorescence detection assay,,An assay in which a material's fluorescence is determined.,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,An assay in which a material's fluorescence is determined.,IEDB,,,,,,fluorescence detection assay,,Using a laser to stimulate a cell culture that was previously labeled with fluorescent antibodies to detect light emmission at a different wavelength in order to determine the presence of surface markers the antibodies are specific for.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001501,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,fluorescence detection assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001762,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-C motif) ligand 21 production by T cells,CCL21/SLC release|RNA/DNA detection,An assay of epitope specific chemokine (C-C motif) ligand 21 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001774,,,,,,,,,,,,,,,,,,,An assay of epitope specific chemokine (C-C motif) ligand 21 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-C motif) ligand 21 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001762,,,,,,,,,,,,,,,,,,,,,,,,CCL21/SLC release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-C motif) ligand 21 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001686,in-situ hybridization,ISH,is an assay using artificially induced nucleic hybridization to localize a specific DNA or RNA sequence in a portion or section of tissue ,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,ISH,,,,,,,,,,,,,,,is an assay using artificially induced nucleic hybridization to localize a specific DNA or RNA sequence in a portion or section of tissue ,PMID:9021518,,,,,,in-situ hybridization,,"Use of in situ hybridization to examine gene expression in the embryonic, neonatal, and adult urogenital system.
PMID:22639265
",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001686,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,in-situ hybridization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra; Marcus Chibucos,,
http://purl.obolibrary.org/obo/OBI_0200118,quantile calculation,,A quantile calculation is a descriptive statistics calculation in which the kth quantile is the data value for which an approximate k fraction of the data is less than or equal to that value.  See http://www.stat.wvu.edu/SRS/Modules/Quantiles/quantiles.html for details.,false,,,http://purl.obolibrary.org/obo/OBI_0200184,,http://purl.obolibrary.org/obo/OBI_0200078,,,,,,,,,,,,,,,,,A quantile calculation is a descriptive statistics calculation in which the kth quantile is the data value for which an approximate k fraction of the data is less than or equal to that value.  See http://www.stat.wvu.edu/SRS/Modules/Quantiles/quantiles.html for details.,WEB: http://www.stat.wvu.edu/SRS/Modules/Quantiles/quantiles.html,,,,,,quantile calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200118,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,quantile calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Monnie McGee,,
http://purl.obolibrary.org/obo/OBI_0001116,vacuum manifold,,"A device that is used for the vacuum-driven processing of multiwell strips or plates, or spin columns. IS THIS AN INSTRUMENT? IS THE DEFINTION CORRECT - TO DISTRIBUTE PRESSURE EVENLY.",false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,"A device that is used for the vacuum-driven processing of multiwell strips or plates, or spin columns. IS THIS AN INSTRUMENT? IS THE DEFINTION CORRECT - TO DISTRIBUTE PRESSURE EVENLY.",PERSON: Erik Segerdell,,,,,,vacuum manifold,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000379,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001116,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,vacuum manifold,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001624,organism identification assay,Organism Detection Method,An assay that identifies the organism species in a specimen.,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,An assay that identifies the organism species in a specimen.,NIAID GSCID-BRC metadata working group,,,,,,organism identification assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001624,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,organism identification assay,,,,,,Organism Detection Method,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000355,hypothesis driven investigation,,is an investigation with the goal to test one or more hypothesis,false,,,http://purl.obolibrary.org/obo/OBI_0000066,,,,,,,,,,,,,,,,,,,is an investigation with the goal to test one or more hypothesis,OBI branch derived,,,,,,hypothesis driven investigation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000355,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,hypothesis driven investigation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0001195,operator variation design,,A study design that assesses the operator performance and relation to data consistency and quality.,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,A study design that assesses the operator performance and relation to data consistency and quality.,MO_519 operator_variation_design,,,,,,operator variation design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001195,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,operator variation design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0002007,SOLiD 3 Plus System,Applied Biosystems SOLiD 3 Plus System,"A DNA sequencer which is manufacted by the Applied Biosystems corporation. Built upon SOLiD sequencing technology, the machine generates greater than 1 billion mappable reads per run.",false,,,http://purl.obolibrary.org/obo/OBI_0000696,,,,Applied Biosystems SOLiD 3 Plus System,,,,,,,,,,,,,,,"A DNA sequencer which is manufacted by the Applied Biosystems corporation. Built upon SOLiD sequencing technology, the machine generates greater than 1 billion mappable reads per run.",http://www3.appliedbiosystems.com/cms/groups/mcb_marketing/documents/generaldocuments/cms_072050.pdf,,,,,,SOLiD 3 Plus System,,"Vissers, Lisenka ELM, et al. ""A de novo paradigm for mental retardation."" Nature genetics 42.12 (2010): 1109-1112. PMID:21076407",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002007,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,SOLiD 3 Plus System,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"PERSON: Venkat Malladi, Chris Stoeckert, Jie Zheng, Alan Ruttenberg",,
http://purl.obolibrary.org/obo/IAO_0000001,conditional specification,,a directive information entity that specifies what should happen if the trigger condition is fulfilled,false,,,http://purl.obolibrary.org/obo/IAO_0000033,,,,,,,,,,,,,,,,,,,a directive information entity that specifies what should happen if the trigger condition is fulfilled,OBI branch derived|OBI_0000349,,,,,,conditional specification,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000001,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,conditional specification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0000575,Bruker Ultrastabilized NMR magnet,,"An NMR magnet manufactured by Bruker for Ultra-High Field NMR, available from 750 MHz to 900 MHz, which provides reliable operation at reduced temperature and ambient pressure via being rigidly mounted and stabilized.",false,,,http://purl.obolibrary.org/obo/OBI_0000597,,,,,,,,,,,,,,,,,NMR instrument,,"An NMR magnet manufactured by Bruker for Ultra-High Field NMR, available from 750 MHz to 900 MHz, which provides reliable operation at reduced temperature and ambient pressure via being rigidly mounted and stabilized.",WEB:<http://www.bruker-biospin.com/nmr_magnets_ultrastabilized.html?&print=http%3A%2Fitsupportunit.com%2Fawstats%2Ficon%2Fnisum%2Fivuj%2F>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400188,,,,,,Bruker Ultrastabilized NMR magnet,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000575,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker Ultrastabilized NMR magnet,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001607,biological activity assay measuring epitope specific tumor necrosis factor (ligand) superfamily member 11 production by T cells,TNFSF11/RANKL release|biological activity,An assay of epitope specific tumor necrosis factor (ligand) superfamily member 11 production by T cells that detects tumor necrosis factor production.,false,,,http://purl.obolibrary.org/obo/OBI_0001400,,,,,,,,,,,,,,,,,,,An assay of epitope specific tumor necrosis factor (ligand) superfamily member 11 production by T cells that detects tumor necrosis factor production.,IEDB,,,,,,biological activity assay measuring epitope specific tumor necrosis factor (ligand) superfamily member 11 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001607,,,,,,,,,,,,,,,,,,,,,,,,TNFSF11/RANKL release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific tumor necrosis factor (ligand) superfamily member 11 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001675,ELISA measuring epitope specific interleukin-17A production by T cells,IL-17A release|ELISA,A T cell epitope specific interleukin-17A production assay that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001773|http://purl.obolibrary.org/obo/OBI_1110162,,,,,,,,,,,,,,,,,,,A T cell epitope specific interleukin-17A production assay that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific interleukin-17A production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001675,,,,,,,,,,,,,,,,,,,,,,,,IL-17A release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific interleukin-17A production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000924,labeled specimen,,A specimen  that has been modified in order to be able to detect it in future experiments,false,,,http://purl.obolibrary.org/obo/OBI_0100051|http://purl.obolibrary.org/obo/OBI_0000953|http://purl.obolibrary.org/obo/OBI_0001936,,,,,,,,,,,,,,,,,,,A specimen  that has been modified in order to be able to detect it in future experiments,,,,,,added during call 3/1/2010,labeled specimen,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000924,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,labeled specimen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI group,,
http://purl.obolibrary.org/obo/OBI_0001601,cytometric bead array assay measuring epitope specific intracellular cytokine staining (ICS) IL-21 production by T cells,IL-21 release|cytometric bead array,An assay of epitope specific interleukin-21 production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001237,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-21 production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific intracellular cytokine staining (ICS) IL-21 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001601,,,,,,,,,,,,,,,,,,,,,,,,IL-21 release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific intracellular cytokine staining (ICS) IL-21 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001302,ELISA measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells,CCL3/MIP-1a release|ELISA,An assay of epitope specific macrophage inflammatory protein-1 alpha production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001333,,,,,,,,,,,,,,,,,,,An assay of epitope specific macrophage inflammatory protein-1 alpha production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001302,,,,,,,,,,,,,,,,,,,,,,,,CCL3/MIP-1a release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000722,paired-end library,mate-paired library|paired-end tag (PET) library,is a collection of short paired tags from the two ends of DNA fragments are extracted and covalently linked as ditag constructs,false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,mate-paired library|paired-end tag (PET) library,,,,,,,,,,,,,,,is a collection of short paired tags from the two ends of DNA fragments are extracted and covalently linked as ditag constructs,adapted from information provided by Solid web site,,,,,,paired-end library,,"PMID: 19339662. Next-generation DNA sequencing of paired-end tags (PET) for transcriptome and genome analyses. Genome Res. 2009 Apr;19(4):521-32. Fullwood MJ, Wei CL, Liu ET, Ruan Y.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000722,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,paired-end library,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001396,stimulus or stress design,,"A study design in which the response of an organism(s) to the stress or stimulus is studied, e.g. osmotic stress, heat shock, radiation exposure, behavioral treatment etc.",false,,,http://purl.obolibrary.org/obo/OBI_0000115,,,,,,,,,,,,,,,,,,,"A study design in which the response of an organism(s) to the stress or stimulus is studied, e.g. osmotic stress, heat shock, radiation exposure, behavioral treatment etc.",MO_568 stimulus_or_stress_design,,,,,,stimulus or stress design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001396,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,stimulus or stress design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/BFO_0000029,site,,,false,,,http://purl.obolibrary.org/obo/BFO_0000141,,,,,,,Site,site,,,,,,,,,,,,,,,,,,site,b is a site means: b is a three-dimensional immaterial entity that is (partially or wholly) bounded by a material entity or it is a three-dimensional immaterial part thereof. (axiom label in BFO2 Reference: [034-002]),the interior of your refrigerator|the hold of a ship|a rabbit hole|your left nostril (a fiat part – the opening – of your left nasal cavity)|the interior of your office|the Piazza San Marco|the interior of the trunk of your car|the Grand Canyon|a hole in the interior of a portion of cheese|an air traffic control region defined in the airspace above an airport|Manhattan Canyon)|the interior of your bedroom|the lumen of your gut|the interior of a kangaroo pouch|the cockpit of an aircraft,,,,,,,,(forall (x) (if (Site x) (ImmaterialEntity x))) // axiom label in BFO2 CLIF: [034-002] ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000029,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,site,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000045,waiting,,not actively doing anything to a material for a duration of time.,false,,,http://purl.obolibrary.org/obo/OBI_0600009,,,,,,,,,,,,,,,,,BP: I have doubts about the utility of this.|We need a better handling/modeling of time (January 2008),,not actively doing anything to a material for a duration of time.,OBI branch derived,,,,,,waiting,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000045,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,waiting,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0000117,Bernoulli trial,,is an assay where the output data is a datum with one of two values denoted success and failure.,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,http://purl.obolibrary.org/obo/OBI_0000441,,,,,,,,,,,,,,,,,is an assay where the output data is a datum with one of two values denoted success and failure.,OBI branch derived,,,,,,Bernoulli trial,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000117,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bernoulli trial,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0001285,in vitro design,,"A study design that is done in a test tube or a culture dish, e.g. A bacterial invasion assay in an established cell culture.",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A study design that is done in a test tube or a culture dish, e.g. A bacterial invasion assay in an established cell culture.",MO_347 in_vitro_design,,,,,,in vitro design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001285,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,in vitro design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0002035,peptide mass fingerprinting,protein fingerprinting|PMF,"A mass spectrometry assay in which an unknown protein of interest is cleaved into smaller peptides, whose absolute masses can be accurately measured with a mass spectrometer.  These masses are then compared to values in a database containing known protein sequences.",false,,,http://purl.obolibrary.org/obo/OBI_0000470,,,,protein fingerprinting|PMF,,,,,,,,,,,,,,,"A mass spectrometry assay in which an unknown protein of interest is cleaved into smaller peptides, whose absolute masses can be accurately measured with a mass spectrometer.  These masses are then compared to values in a database containing known protein sequences.",ERO:0001668 (http://en.wikipedia.org/wiki/Peptide_mass_fingerprinting),,,,,Details see tracker: https://sourceforge.net/p/obi/obi-terms/725/,peptide mass fingerprinting,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002035,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,peptide mass fingerprinting,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Saccharomyces Genome Database (SGD),,,,,,,,"Janos Demeter, Chris Stoeckert",,
http://purl.obolibrary.org/obo/OBI_0001518,epitope specific tumor necrosis factor (ligand) superfamily member 11 production by T cells,,A process of tumor necrosis factor (ligand) superfamily member 11 production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/OBI_0001351|http://purl.obolibrary.org/obo/GO_0072535,,,,,,,,,,,,,,,,,Date: 2011-11-10; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mappings: assay_mappings.owl,,A process of tumor necrosis factor (ligand) superfamily member 11 production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific tumor necrosis factor (ligand) superfamily member 11 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001518,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific tumor necrosis factor (ligand) superfamily member 11 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0200060,t cell epitope prediction,,"A T cell epitope prediction takes as input an antigen sequence, and through an analysis of this sequence, produces as output a prediction of the likelihood the biomaterial is a T cell epitope.",false,,,http://purl.obolibrary.org/obo/OBI_0200187,,http://purl.obolibrary.org/obo/OBI_0200081,,,,,,,,,,,,,,,,,"A T cell epitope prediction takes as input an antigen sequence, and through an analysis of this sequence, produces as output a prediction of the likelihood the biomaterial is a T cell epitope.",PERSON: Helen Parkinson,,,,,,t cell epitope prediction,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200060,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,t cell epitope prediction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0500010,reference design,,A reference experiment design type is where all samples are compared to a common reference.,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,A reference experiment design type is where all samples are compared to a common reference.,MO_699,,,,,,reference design,,PMID: 12933549,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500010,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,reference design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra on behalf of MO,,
http://purl.obolibrary.org/obo/OBI_0000952,oral administration,,The administration of a substance into the mouth of an organism,false,,,http://purl.obolibrary.org/obo/OBI_0600007,,http://purl.obolibrary.org/obo/OBI_0000434,,,,,,,,,,,,,,,,,The administration of a substance into the mouth of an organism,,,,,,,oral administration,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000952,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,oral administration,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0002048,Illumina HiSeq 3000,HiSeq 3000,"A DNA sequencer manufactured by Illumina corporation, with a single flow cell and a throughput of more than 200 Gb per day.",false,,,http://purl.obolibrary.org/obo/OBI_0400103,,,,HiSeq 3000,,,,,,,,,,,,,,,"A DNA sequencer manufactured by Illumina corporation, with a single flow cell and a throughput of more than 200 Gb per day.",http://www.illumina.com/systems/hiseq-3000-4000.html,,,,,,Illumina HiSeq 3000,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002048,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Illumina HiSeq 3000,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Sagar Jain, Richard Scheuermann",,
http://purl.obolibrary.org/obo/OBI_0001310,species comparison design,,A study design that assays differences between distinct species.,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,A study design that assays differences between distinct species.,MO_675 species_design,,,,,,species comparison design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000268,,,,,,,,,,,,,,,,OBI:0001310,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,species comparison design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001067,perfusion station,,A device or system in which perfusion units are integrated.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A device or system in which perfusion units are integrated.,PERSON: Erik Segerdell,,,,,,perfusion station,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0001036,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001067,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,perfusion station,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0400073,metal vapor laser,,A metal vapor laser is a gas laser in which the lasing medium is metal vapor. A metal vapor laser can by used to irradiate cells in a flow cytometer.,false,,,http://purl.obolibrary.org/obo/OBI_0400047,,,,,,,,,,,,,,,,,,,A metal vapor laser is a gas laser in which the lasing medium is metal vapor. A metal vapor laser can by used to irradiate cells in a flow cytometer.,"Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253",,,,,,metal vapor laser,,"Gold vapor laser, Helium-cadmium metal-vapor laser",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400073,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,metal vapor laser,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0001806,intracellular cytokine staining assay measuring epitope specific interleukin-27 production by T cells,IL-27 release|ICS,An assay of epitope specific interleukin-27 production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001198,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-27 production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-27 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001806,,,,,,,,,,,,,,,,,,,,,,,,IL-27 release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-27 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001638,antigen inhibition assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex approximated by IC50,dissociation constant KD|antigen inhibition (~ IC50)|nM,A B cell epitope equilibrium dissociation constant (KD) assay that provides IC50 values determined under assay conditions where the IC50 approximates a KD value using a B cell epitope antigen inhibition of binding assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001708,,,,,,,,,,,,,,,,,,,A B cell epitope equilibrium dissociation constant (KD) assay that provides IC50 values determined under assay conditions where the IC50 approximates a KD value using a B cell epitope antigen inhibition of binding assay.,IEDB,,,,,,antigen inhibition assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex approximated by IC50,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001571,,,OBI:0001638,,,,,,,,,,,,,,,,,,,,,,,,dissociation constant KD|antigen inhibition (~ IC50)|nM,,,,,,,,,,,,,,,,,,,,,,antigen inhibition assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex approximated by IC50,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000076,unplanned occurrence effecting an investigation,,a process which is external in origin to the investigation that has an impact on the outcome.,false,,,http://purl.obolibrary.org/obo/BFO_0000015,,,,,,,,,,,,,,,,,,,a process which is external in origin to the investigation that has an impact on the outcome.,OBI,,,,,,unplanned occurrence effecting an investigation,,"Earthquake that destroys the lab, an outside investigator discovering an adverse effect of the reagants used",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000076,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,unplanned occurrence effecting an investigation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000725,host role,,"host role is a role played by an organism and realized by providing nourishment, shelter or a means of reproduction to another organism within the organism playing the host role",false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,,,"host role is a role played by an organism and realized by providing nourishment, shelter or a means of reproduction to another organism within the organism playing the host role",OBI|30 Mar09 submitted by vaccine community|http://en.wikipedia.org/wiki/Host_(biology),,,,,"30Mar09 virus reproducing inside a cell; bacteria causing a disease, host can be harmed or not.  we want to avoid a cat sitting on my lap and an animal care technician; these are not examples or hosts; dental cares = on tooth, but part of outer layer of tooth, so covered by ""within"" in the definition",host role,,"In biology, a host is an organism that harbors a virus or parasite, or a mutual or commensal symbiont, typically providing nourishment and shelter.  http://en.wikipedia.org/wiki/Host_(biology)  30 March 09",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000725,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100026,,,,,,,,,,,,,,,,,host role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP: Role Branch,,
http://purl.obolibrary.org/obo/OBI_0200151,exponential base,,The exponential base is a feature of an exponential function which is defined in http://en.wikipedia.org/wiki/Exponential_function. Its value can be any positive real number (typically different from 1).,false,,,http://purl.obolibrary.org/obo/OBI_0200140,,,,,,,,,,,,,,,,,,,The exponential base is a feature of an exponential function which is defined in http://en.wikipedia.org/wiki/Exponential_function. Its value can be any positive real number (typically different from 1).,WEB: http://en.wikipedia.org/wiki/Exponential_function,,,,,,exponential base,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200151,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,exponential base,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0500011,latin square design,,Latin square design is_a study design which allows in its simpler form controlling 2 levels of nuisance variables (also known as blocking variables).he 2 nuisance factors are divided into a tabular grid with the property that each row and each column receive each treatment exactly once.,false,,,http://purl.obolibrary.org/obo/OBI_0500007,,,,,,,,,,,,,,,,,,,Latin square design is_a study design which allows in its simpler form controlling 2 levels of nuisance variables (also known as blocking variables).he 2 nuisance factors are divided into a tabular grid with the property that each row and each column receive each treatment exactly once.,Adapted from: http://www.itl.nist.gov/div898/handbook/pri/section3/pri3321.htm and,,,,,,latin square design,,"PMID: 17582121-Our objective was to examine the effects of dietary cation-anion difference (DCAD) with different concentrations of dietary crude protein (CP) on performance and acid-base status in early lactation cows. Six lactating Holstein cows averaging 44 d in milk were used in a 6 x 6 Latin square design with a 2 x 3 factorial arrangement of treatments: DCAD of -3, 22, or 47 milliequivalents (Na + K - Cl - S)/100 g of dry matter (DM), and 16 or 19% CP on a DM basis. Linear increases with DCAD occurred in DM intake, milk fat percentage, 4% fat-corrected milk production, milk true protein, milk lactose, and milk solids-not-fat. Milk production itself was unaffected by DCAD. Jugular venous blood pH, base excess and HCO3(-) concentration, and urine pH increased, but jugular venous blood Cl- concentration, urine titratable acidity, and net acid excretion decreased linearly with increasing DCAD. An elevated ratio of coccygeal venous plasma essential AA to nonessential AA with increasing DCAD indicated that N metabolism in the rumen was affected, probably resulting in more microbial protein flowing to the small intestine. Cows fed 16% CP had lower urea N in milk than cows fed 19% CP; the same was true for urea N in coccygeal venous plasma and urine. Dry matter intake, milk production, milk composition, and acid-base status did not differ between the 16 and 19% CP treatments. It was concluded that DCAD affected DM intake and performance of dairy cows in early lactation. Feeding 16% dietary CP to cows in early lactation, compared with 19% CP, maintained lactation performance while reducing urea N excretion in milk and urine.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500011,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,latin square design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000597,Bruker NMR magnet,,An NMR magnet that is manufactured by Bruker.,false,,,http://purl.obolibrary.org/obo/OBI_0000517,,,,,,,,,,,,,,,,,NMR instrument,,An NMR magnet that is manufactured by Bruker.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400186,,,,,,Bruker NMR magnet,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000597,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker NMR magnet,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001182,negative binding datum,,A binding datum that states that there is no significant disposition of two or more entities to form a complex,false,,,http://purl.obolibrary.org/obo/OBI_0001181,,,,,,,,,,,,,,,,,,,A binding datum that states that there is no significant disposition of two or more entities to form a complex,,,,,,,negative binding datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001182,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,negative binding datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0400082,photodetector,,"A photodetector is a device used to detect and measure the intensity of radiant energy through photoelectric action. In a cytometer, photodetectors measure either the number of photons of laser light scattered on impact with a cell (for example), or the flourescence emitted by excitation of a fluorescent dye.",false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,"A photodetector is a device used to detect and measure the intensity of radiant energy through photoelectric action. In a cytometer, photodetectors measure either the number of photons of laser light scattered on impact with a cell (for example), or the flourescence emitted by excitation of a fluorescent dye.",http://einstein.stanford.edu/content/glossary/glossary.html,,,,,,photodetector,,"A photomultiplier tube, a photo diode",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400082,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,photodetector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0400031,dichroic mirror,,A dichroic mirror is an optical filter which is used to selectively reflect light of a small range of colors while passing other colors. A dichroic filter passes the specified range of light whereas a dichroic mirror reflects the specified range of light.,false,,,http://purl.obolibrary.org/obo/OBI_0400079,,,,,,,,,,,,,,,,,,,A dichroic mirror is an optical filter which is used to selectively reflect light of a small range of colors while passing other colors. A dichroic filter passes the specified range of light whereas a dichroic mirror reflects the specified range of light.,http://en.wikipedia.org/wiki/Dichroic_mirror,,,,,,dichroic mirror,,ViewLux Alexa 594 dichroic mirror,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400031,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,dichroic mirror,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/GO_0071613,granzyme B production,,"The appearance of granzyme B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,"The appearance of granzyme B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,granzyme B production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0071613,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,granzyme B production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0071612,IP-10 production,,"The appearance of IP-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0032602,,,,,,,,,,,,,,,,,,,"The appearance of IP-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,IP-10 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0071612,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,IP-10 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0071610,chemokine (C-C motif) ligand 1 production,,"The appearance of chemokine (C-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0032602,,,,,,,,,,,,,,,,,,,"The appearance of chemokine (C-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,chemokine (C-C motif) ligand 1 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0071610,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,chemokine (C-C motif) ligand 1 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0071611,granulocyte colony-stimulating factor production,,"The appearance of granulocyte colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of granulocyte colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,granulocyte colony-stimulating factor production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0071611,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,granulocyte colony-stimulating factor production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000393,signal conversion function,transduction function,"A signal conversion function is an information processor function which transforms a signal into another type of signal. For example an analog-to-digital_converter, Ac/Ac converter, a synapse converts electrical action potentials into an intermediate chemical signal. The post synapse converts it back into an electric one passed on to the axon.",false,,,http://purl.obolibrary.org/obo/OBI_0000392,,,,transduction function,,,,,,,,,,,,,,,"A signal conversion function is an information processor function which transforms a signal into another type of signal. For example an analog-to-digital_converter, Ac/Ac converter, a synapse converts electrical action potentials into an intermediate chemical signal. The post synapse converts it back into an electric one passed on to the axon.",,,,,,,signal conversion function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000393,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,signal conversion function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bill Bug|Daniel Schober|Frank Gibson|Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_1000042,peptide construct,,a material entity synthesized to contain a number of peptides conjugated together in a non-linear fashion,false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,,,,,,,,,,,,,,,,a material entity synthesized to contain a number of peptides conjugated together in a non-linear fashion,IEDB,,,,,,peptide construct,,"Multiple Antigenic Peptide (MAP) construct containing T and B cell epitopes from p. falciparum congugated to a central glycin

A novel multivalent human CTL peptide construct elicits robust cellular immune responses in HLA-A*0201 transgenic mice: implications for HTLV-1 vaccine design. Vaccine. 2003 Jun 20;21(21-22):2767-81. PMID: 12798617",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_16670,,,,,,,,,,,,,,,,OBI:1000042,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0302892,,,peptide construct,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001816,epitope specific chemokine (C-X-C motif) ligand 13 production by T cells,,A process of chemokine (C-X-C motif) ligand 13 production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0097391|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,Date: 2012-11-16; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mappings: MMExpressionsTcell.txt,,A process of chemokine (C-X-C motif) ligand 13 production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific chemokine (C-X-C motif) ligand 13 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001816,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific chemokine (C-X-C motif) ligand 13 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000581,y-column connector,,"A column connector that connects one column on one side with two columns at the other side, hence building a Y shaped structure.",false,,,http://purl.obolibrary.org/obo/OBI_0000478,,,,,,,,,,,,,,,,,,,"A column connector that connects one column on one side with two columns at the other side, hence building a Y shaped structure.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01237,,,,,,y-column connector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000581,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,y-column connector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000204,nutrient role,nutrient,a role that inheres in a material entity and is realized in the use of that material entity by an organism when it is used in that organism's metabolism and provides nourishment.,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,nutrient,,,,,,,,,,,,,19 Feb 2009; old def: A nutrient role is a role played by a substance used in an organism's metabolism which is taken in from the environment and provides nourishment.,,a role that inheres in a material entity and is realized in the use of that material entity by an organism when it is used in that organism's metabolism and provides nourishment.,"Wikipedia, feb 29, 2008",,,,,,nutrient role,,Luria broth; vitamin A; A nutrient is a substance used in an organism's metabolism which must be taken in from the environment.  Wikipedia.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000204,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,nutrient role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP:  Role branch,,
http://purl.obolibrary.org/obo/OBI_0000426,injection,,"injection is process which aims at introducing a compound or a mixture into a material entity (either biological entity or instrument) by relying on devices such as syringe or injector connection, attached or forced into a vascular system (veins of an organism or tubes of a machine) or in a tissue.",false,,,http://purl.obolibrary.org/obo/OBI_0000274,,http://purl.obolibrary.org/obo/OBI_0000434,,,,,,,,,,,,,,,,,"injection is process which aims at introducing a compound or a mixture into a material entity (either biological entity or instrument) by relying on devices such as syringe or injector connection, attached or forced into a vascular system (veins of an organism or tubes of a machine) or in a tissue.",OBI Biomaterial,,,,,,injection,,Multiple Small-Dose Injections Can Reduce the Passage of Sclerosant Foam into Deep Veins During Foam Sclerotherapy for Varicose Veins. Eur J Vasc Endovasc Surg. 2008 Oct 13. PMID: 18922712,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000426,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,injection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001241,cell culture analyte detection bioassay measuring epitope specific interleukin-4 production by T cells,IL-4 release|bioassay,An assay of epitope specific interleukin-4 production by T cells that uses a cell culture analyte detection bioassay.,false,,,http://purl.obolibrary.org/obo/OBI_0001450,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-4 production by T cells that uses a cell culture analyte detection bioassay.,IEDB,,,,,,cell culture analyte detection bioassay measuring epitope specific interleukin-4 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001241,,,,,,,,,,,,,,,,,,,,,,,,IL-4 release|bioassay,,,,,,,,,,,,,,,,,,,,,,cell culture analyte detection bioassay measuring epitope specific interleukin-4 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0002026,Human Genome U133 tiling array,Affymetrix HT Human Genome U133 Array Plate Set|HG-U133 array|HG-U133,"A tiling array which is manufactured by the Affymetrix corporation. Built to analyze DNA sequence copy number by comparative genomic hybridization for human DNA against 39,000 transcripts and variants.",false,,,http://purl.obolibrary.org/obo/OBI_0001307,,,,Affymetrix HT Human Genome U133 Array Plate Set|HG-U133 array|HG-U133,,,,,,,,,,,,,,,"A tiling array which is manufactured by the Affymetrix corporation. Built to analyze DNA sequence copy number by comparative genomic hybridization for human DNA against 39,000 transcripts and variants.",http://www.affymetrix.com/estore/esearch/search.jsp?pd=131441&N=4294967292,,,,,,Human Genome U133 tiling array,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002026,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Human Genome U133 tiling array,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000151,filter paper,,a device manufacture with the intent to provide a porous unsized paper used for filtering.,false,,,http://purl.obolibrary.org/obo/OBI_0000932,,,,,,,,,,,,,,,,,,,a device manufacture with the intent to provide a porous unsized paper used for filtering.,sep:00107,,,,,,filter paper,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000378,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000151,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,filter paper,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Frank Gibson,,
http://purl.obolibrary.org/obo/OBI_0001743,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-1 beta production by T cells,IL-1b release|RNA/DNA detection,An assay of epitope specific interleukin-1 beta production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001449,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-1 beta production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-1 beta production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001743,,,,,,,,,,,,,,,,,,,,,,,,IL-1b release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-1 beta production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_1110151,ELISA measuring epitope specific interferon-gamma production by T cells,IFNg release|ELISA,An assay of epitope specific interferon-gamma production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001414,,,,,,,,,,,,,,,,,,,An assay of epitope specific interferon-gamma production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific interferon-gamma production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110151,,,,,,,,,,,,,,,,,,,,,,,,IFNg release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific interferon-gamma production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0302745,obsolete_adipose tissue,,"adipose tissue is a tissue which main constituents are adipocytes. adipose tissue can be classified base on its location (site) but also based on adipocyte subtypes (brown or white) which reflect functional differences and is only found in animals, Vertebrates or invertebrates.",true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,PRS: this class has been added during major biomaterial.owl cleanup for evaluation and testing of imports from CARO,,"adipose tissue is a tissue which main constituents are adipocytes. adipose tissue can be classified base on its location (site) but also based on adipocyte subtypes (brown or white) which reflect functional differences and is only found in animals, Vertebrates or invertebrates.",GROUP: OBI Biomaterial derived,,,,,,obsolete_adipose tissue,,PMID: 18435934.Fatty acid composition of adipose tissue and blood in humans and its use as a biomarker of dietary intake.Prog Lipid Res. 2008 Apr 4.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000228,,,,,,,,,,,,,,,,,,OBI:0302745,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_adipose tissue,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/PATO_0000186,behavioral quality,,An organismal quality inhering in a bearer by virtue of the bearer's behavior aggregate of the responses or reactions or movements in a given situation.,false,,,http://purl.obolibrary.org/obo/PATO_0001237,,,,,,,,,,,,,,,,,,,An organismal quality inhering in a bearer by virtue of the bearer's behavior aggregate of the responses or reactions or movements in a given situation.,,,,,,,behavioral quality,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0000186,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,behavioral quality,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001668,split-ubiquitin assay ,,"is a kind of yeast 2 hybrid system which enables membrane soluble proteins to be screened.  two integral membrane proteins to be studied are fused to two different ubiquitin moieties: a C-terminal ubiquitin moiety (\""Cub\"", residues 35–76) and an N-terminal ubiquitin moiety (\""Nub\"", residues 1–34). These fused proteins are called the bait and prey, respectively. In addition to being fused to an integral membrane protein, the Cub moiety is also fused to a transcription factor (TF) that can be cleaved off by ubiquitin specific proteases. Upon bait–prey interaction, Nub and Cub-moieties assemble, reconstituting the split-ubiquitin. The reconstituted split-ubiquitin molecule is recognized by ubiquitin specific proteases, which cleave off the reporter protein, allowing it to induce the transcription of reporter genes.",false,,,http://purl.obolibrary.org/obo/OBI_0000070|http://purl.obolibrary.org/obo/OBI_0001146,,,,,,,,,,,,,,,,,add regulatory region DNA binding;sequence-specific DNA binding;obo:GO:0000975;obo:GO:0043565;,,"is a kind of yeast 2 hybrid system which enables membrane soluble proteins to be screened.  two integral membrane proteins to be studied are fused to two different ubiquitin moieties: a C-terminal ubiquitin moiety (\""Cub\"", residues 35–76) and an N-terminal ubiquitin moiety (\""Nub\"", residues 1–34). These fused proteins are called the bait and prey, respectively. In addition to being fused to an integral membrane protein, the Cub moiety is also fused to a transcription factor (TF) that can be cleaved off by ubiquitin specific proteases. Upon bait–prey interaction, Nub and Cub-moieties assemble, reconstituting the split-ubiquitin. The reconstituted split-ubiquitin molecule is recognized by ubiquitin specific proteases, which cleave off the reporter protein, allowing it to induce the transcription of reporter genes.",adapted from wikipedia,,,,,,split-ubiquitin assay ,,"Split-ubiquitin two-hybrid assay to analyze protein-protein interactions at the endosome: application to Saccharomyces cerevisiae Bro1 interacting with ESCRT complexes, the Doa4 ubiquitin hydrolase, and the Rsp5 ubiquitin ligase.
Nikko E, André B.
Eukaryot Cell. 2007 Aug;6(8):1266-77. Epub 2007 May 18.
PMID: 17513562 ",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001668,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,split-ubiquitin assay ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra; Marcus Chibucos,,
http://purl.obolibrary.org/obo/OBI_0000834,high molecular weight DNA extract,,The output of an extraction process in which DNA molecules above a molecular weight cutoff are purified in order to exclude DNA from organellas.,false,,,http://purl.obolibrary.org/obo/OBI_0001051,,,,,,,,,,,,,,,,,,,The output of an extraction process in which DNA molecules above a molecular weight cutoff are purified in order to exclude DNA from organellas.,OBI,,,,,,high molecular weight DNA extract,,Extraction of chromosomal DNA from mammalian cells by first isolating nucei,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000834,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,high molecular weight DNA extract,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0000257,DNA extraction,,A DNA extraction is a nucleic acid extraction where the desired output material is DNA.,false,,,http://purl.obolibrary.org/obo/OBI_0666667,,,,,,,,,,,,,,,,,,,A DNA extraction is a nucleic acid extraction where the desired output material is DNA.,OBI branch derived,,,,,,DNA extraction,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_16991,,,OBI:0000257,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNA extraction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0001114,nucleic acid extraction/purification instrument,,A device that is used to isolate and collect nucleic acids (DNA or RNA) for subsequent molecular analysis.,false,,,http://purl.obolibrary.org/obo/OBI_0000932,,,,,,,,,,,,,,,,,,,A device that is used to isolate and collect nucleic acids (DNA or RNA) for subsequent molecular analysis.,PERSON: Erik Segerdell,,,,,,nucleic acid extraction/purification instrument,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000372,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001114,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,nucleic acid extraction/purification instrument,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001596,PDB file chain,,A 3D structural organization datum that is part of a PDB file and has a specific chain identifier that identifies the entire information on a subset of the material entities ,false,,,http://purl.obolibrary.org/obo/OBI_0001155,,,,,,,,,,,,,,,,,,,A 3D structural organization datum that is part of a PDB file and has a specific chain identifier that identifies the entire information on a subset of the material entities ,IEDB,,,,,,PDB file chain,,The 'D' chain in the PDB file 2BSE identifies the heavy chain of the antibody in the protein:antibody complex,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001525,OBI:0001596,http://purl.obolibrary.org/obo/OBI_0001525,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PDB file chain,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Bjoern Peters, Dorjee Tamang, Jason Greenbaum",,
http://purl.obolibrary.org/obo/IAO_0000577,centrally registered identifier symbol,CRID symbol,A symbol that is part of a CRID and that is sufficient to look up a record from the CRID's registry.,false,,,http://purl.obolibrary.org/obo/IAO_0000028,,,,CRID symbol,,,,,,,,,,,,,,,A symbol that is part of a CRID and that is sufficient to look up a record from the CRID's registry.,"Original proposal from Bjoern, discussions at IAO calls",,,,,,centrally registered identifier symbol,,"The sentence ""The article has Pubmed ID 12345."" contains a CRID that has two parts: one part is the CRID symbol, which is '12345'; the other part denotes the CRID registry, which is Pubmed.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000578,IAO:0000577,http://purl.obolibrary.org/obo/IAO_0000578,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,centrally registered identifier symbol,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters|PERSON: Melanie Courtot|PERSON: Bill Hogan|PERSON: Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0001243,cytometric bead array assay measuring epitope specific monocyte chemotactic protein-1 production by T cells,CCL2/MCP-1 release|cytometric bead array,An assay of epitope specific monocyte chemotactic protein-1 production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001465,,,,,,,,,,,,,,,,,,,An assay of epitope specific monocyte chemotactic protein-1 production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific monocyte chemotactic protein-1 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001243,,,,,,,,,,,,,,,,,,,,,,,,CCL2/MCP-1 release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific monocyte chemotactic protein-1 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/BFO_0000182,history,,,false,,,http://purl.obolibrary.org/obo/BFO_0000015,,,,,,,History,history,,,,,,,,,,,,,,,,,,history,"A history is a process that is the sum of the totality of processes taking place in the spatiotemporal region occupied by a material entity or site, including processes on the surface of the entity or within the cavities to which it serves as host. (axiom label in BFO2 Reference: [138-001])",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000182,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,history,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0001396,cellular quality,,A monadic quality of continuant that exists at the cellular level of organisation.,false,,,http://purl.obolibrary.org/obo/PATO_0001237,,,,,,,,,,,,,,,,,,,A monadic quality of continuant that exists at the cellular level of organisation.,,,,,,,cellular quality,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001396,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,cellular quality,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0001394,diploid,,"A ploidy quality inhering in a bearer by virtue of the bearer's having two copies (homologs) of each chromosome, usually one from the mother and one from the father.",false,,,http://purl.obolibrary.org/obo/PATO_0001374,,,,,,,,,,,,,,,,,,,"A ploidy quality inhering in a bearer by virtue of the bearer's having two copies (homologs) of each chromosome, usually one from the mother and one from the father.",,,,,,,diploid,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001394,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,diploid,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000215,role of legally acceptable representative,legally acceptable representative,"a role which inheres in a human or organization who are able subject to applicable law to consent, on behalf of a prospective subject, to the subject`s participation in as clinical trial.",false,,,http://purl.obolibrary.org/obo/OBI_0000016,,,,legally acceptable representative,,,,,,,,,,,,,,,"a role which inheres in a human or organization who are able subject to applicable law to consent, on behalf of a prospective subject, to the subject`s participation in as clinical trial.","OBI, CDISC",,,,,"legally acceptable representative. An individual or juridical or other body authorized under applicable law to consent, on behalf of a prospective subject, to the subject's participation in the clinical trial. [ICH, E6 Glossary]",role of legally acceptable representative,,"Parent of minor patient;  Definition of legally acceptable representative
An individual or juridicial or other body authorized under applicable law to consent, on behalf of a prospective subject, to the subject`s participation in the clinical trial. http://www.geneed.com/website/catalog/glossary_search.php?id=2134&search_term=legally%20acceptable%20representative&select=TRUE",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000215,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,role of legally acceptable representative,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jennifer Fostel|Person:Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0000091,detector reagent role,,a role which inheres in a molecular entity and is realized by the process of recording or registering a stimulus.,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,,,a role which inheres in a molecular entity and is realized by the process of recording or registering a stimulus.,"One that detects, especially a mechanical, electrical, or chemical device that automatically identifies and records or registers a stimulus, such as an environmental change in pressure or temperature, an electric signal, or radiation from a radioactive material.   http://www.answers.com/topic/detector  19feb2009",,,,,19feb2009.  not clear we need this term.  originally if came from microarrays -- the probes on the array are termed detectors in some instances,detector reagent role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000091,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,detector reagent role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000219,cellular feature identification objective,,"Cellular_feature_identification_objective is a biological_feature_identification_objective role describing a study designed to examine or characterize a biological feature monitored at the cellular level, e.g. stage of cell cycle, stage of differentiation.",false,,,http://purl.obolibrary.org/obo/OBI_0000015,,,,,,,,,,,,,,,,,,,"Cellular_feature_identification_objective is a biological_feature_identification_objective role describing a study designed to examine or characterize a biological feature monitored at the cellular level, e.g. stage of cell cycle, stage of differentiation.",,,,,,,cellular feature identification objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000219,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cellular feature identification objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0000661,enzyme-linked immunosorbent assay,ELISA,"An analyte assay where binding of an enzyme linked antibody to a material entity that is immobilized on solid support is detected utilizing a chemiluminescent reaction. Depending on the setup, the enzyme-linked antibody could be binding directly to the analyte, or it serves as a secondary antibody detecting binding of the primary antibody to the analyte.",false,,,http://purl.obolibrary.org/obo/OBI_0000443,,,,ELISA,,,,,,,,,,,,,,,"An analyte assay where binding of an enzyme linked antibody to a material entity that is immobilized on solid support is detected utilizing a chemiluminescent reaction. Depending on the setup, the enzyme-linked antibody could be binding directly to the analyte, or it serves as a secondary antibody detecting binding of the primary antibody to the analyte.",IEDB,,,,,,enzyme-linked immunosorbent assay,,"1) Detection of IL-2 (analyte) in a cell supernatant (evaluant), using plate bound anti IL-2 antibodies, and a reporter enzyme-linked reporter antibody. 2) Measurement of IgG antibody (analyte) titer in a serum sample (evaluant) using plate bound antigen and a reporter anti-IgG antibody.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000661,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,enzyme-linked immunosorbent assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/CHEBI_59053,N-cyclohexyl-N'-(2-(4-morpholinyl)ethyl)carbodiimide,,A carbodiimide having cyclcohexyl and 2-(4-morpholinyl)ethyl as the two N-substituents.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,A carbodiimide having cyclcohexyl and 2-(4-morpholinyl)ethyl as the two N-substituents.,,,,,,,N-cyclohexyl-N'-(2-(4-morpholinyl)ethyl)carbodiimide,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:59053,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,N-cyclohexyl-N'-(2-(4-morpholinyl)ethyl)carbodiimide,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000550,nitrogen generator,,A gas generator that generates nitrogen gas.,false,,,http://purl.obolibrary.org/obo/OBI_0000507,,,,,,,,,,,,,,,,,,,A gas generator that generates nitrogen gas.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01034,,,,,,nitrogen generator,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000550,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,nitrogen generator,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_1110053,cancer,,A disease characterized by abnormal and uncontrolled cell division,false,,,http://purl.obolibrary.org/obo/OGMS_0000031,,,,,,,,,,,,,,,,,,,A disease characterized by abnormal and uncontrolled cell division,IEDB,,,,,,cancer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110053,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cancer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000368,record function,,A record function is a function that registers or collects information in a particular format on a particular recording medium. For example on paper or a digital representation,false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,A record function is a function that registers or collects information in a particular format on a particular recording medium. For example on paper or a digital representation,,,,,,,record function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000368,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,record function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bill Bug|Daniel Schober|Frank Gibson|Melanie Courtot,,
http://purl.obolibrary.org/obo/IAO_0000300,textual entity,text,"A textual entity is a part of a manifestation (FRBR sense), a generically dependent continuant whose concretizations are patterns of glyphs intended to be interpreted as words, formulas, etc.",false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,text,,,,,,,,,,,,,,,"A textual entity is a part of a manifestation (FRBR sense), a generically dependent continuant whose concretizations are patterns of glyphs intended to be interpreted as words, formulas, etc.",,,,,,"MC, 2009-09-14 (following IAO call 2009-09-01): textual entities live at the FRBR (http://en.wikipedia.org/wiki/Functional_Requirements_for_Bibliographic_Records) manifestation level. Everything is significant: line break, pdf and html versions of same document are different textual entities.|AR, (IAO call 2009-09-01): a document as a whole is not typically a textual entity, because it has pictures in it - rather there are parts of it that are textual entities. Examples: The title, paragraph 2 sentence 7, etc.",textual entity,,"Words, sentences, paragraphs, and the written (non-figure) parts of publications are all textual entities",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000300,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,textual entity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0000518,trap column,,"A trap column is a chromatography column which is used prior to a, e.g. mass spectrometry, separation to clean up or concentrate controlled amounts of samples prior to elution to a detector.",false,,,http://purl.obolibrary.org/obo/OBI_0000038,,,,,,,,,,,,,,,,,,,"A trap column is a chromatography column which is used prior to a, e.g. mass spectrometry, separation to clean up or concentrate controlled amounts of samples prior to elution to a detector.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01261,,,,,,trap column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000518,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,trap column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001232,biological activity assay measuring epitope specific RANTES production by T cells,CCL5/RANTES release|biological activity,A T cell epitope specific cytokine production assay that detects RANTES production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects RANTES production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific RANTES production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001232,,,,,,,,,,,,,,,,,,,,,,,,CCL5/RANTES release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific RANTES production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001035,Nuclease S1 structure mapping assay,single nucleotide resolution mapping assay using Nuclease S1,a single-nucleotide-resolution deoxyribonucleic acid structure mapping assay which uses DNAse 1 as reagent and enzymatic probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,false,,,http://purl.obolibrary.org/obo/OBI_0001014,,http://purl.obolibrary.org/obo/OBI_0000441,,single nucleotide resolution mapping assay using Nuclease S1,,,,,,,,,,,,,,,a single-nucleotide-resolution deoxyribonucleic acid structure mapping assay which uses DNAse 1 as reagent and enzymatic probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,RNA ontology,,,,,,Nuclease S1 structure mapping assay,,PMID:363143,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_33697,,,,OBI:0001035,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Nuclease S1 structure mapping assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001234,epigenetic modification identification objective,,"A molecular feature identification objective that aims to detect epigenetic modifications, such as DNA methylation, histone modifications.",false,,,http://purl.obolibrary.org/obo/OBI_0000131,,,,,,,,,,,,,,,,,,,"A molecular feature identification objective that aims to detect epigenetic modifications, such as DNA methylation, histone modifications.",Person: Chris Stoeckert,,,,,,epigenetic modification identification objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001234,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epigenetic modification identification objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0600018,material portioning,aliquoting|apportioning,a material processing in which the input substance is partitioned into a number of portions that are similar in composition.,false,,,http://purl.obolibrary.org/obo/OBI_0600014,,http://purl.obolibrary.org/obo/OBI_0000678,,aliquoting|apportioning,,,,,,,,,,,,,,,a material processing in which the input substance is partitioned into a number of portions that are similar in composition.,OBI branch derived,,,,,,material portioning,,pouring 50 mL aliquots of fetal calf serum into conical tubes from a 500 mL stock,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600018,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,material portioning,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001494,linear amplification,,An enzymatic amplification which amplifies nucleic acid sequence by making many copies off the same template.,false,,,http://purl.obolibrary.org/obo/OBI_0600058,,,,,,,,,,,,,,,,,,,An enzymatic amplification which amplifies nucleic acid sequence by making many copies off the same template.,MO_997 linear_amplification,,,,,,linear amplification,,An example is the use of the T7 promoter for amplification by transcribing many RNA copies.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001494,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,linear amplification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001769,specimen collector role,,"An Investigation agent role borne by a person or organization which 
is realized in a specimen collection process.",false,,,http://purl.obolibrary.org/obo/OBI_0000202,,,,,,,,,,,,,,,,,,,"An Investigation agent role borne by a person or organization which 
is realized in a specimen collection process.",Penn Group,,,,,,specimen collector role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001769,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,specimen collector role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"Person: Jie Zheng, Chris Stoeckert",,
http://purl.obolibrary.org/obo/OBI_0001370,intracellular cytokine staining assay measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells,CCL4/MIP-1b release|ICS,An assay of epitope specific chemokine (C-C motif) ligand 4 production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001345,,,,,,,,,,,,,,,,,,,An assay of epitope specific chemokine (C-C motif) ligand 4 production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001370,,,,,,,,,,,,,,,,,,,,,,,,CCL4/MIP-1b release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001690,molecular function identification objective,,is an objective specification which aims to discover molecular function realized by a molecular entity,false,,,http://purl.obolibrary.org/obo/OBI_0000015,,,,,,,,,,,,,,,,,,,is an objective specification which aims to discover molecular function realized by a molecular entity,OBI group,,,,,,molecular function identification objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001690,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,molecular function identification objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0600064,recombinant vector cloning,molecular cloning,a planned process with the objective to insert genetic material into a cloning vector for future replication of the inserted material,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,molecular cloning,,,,,,,,,,,,,,,a planned process with the objective to insert genetic material into a cloning vector for future replication of the inserted material,OBI branch derived,,,,,,recombinant vector cloning,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000737,http://purl.obolibrary.org/obo/OBI_0000731,,,OBI:0600064,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,recombinant vector cloning,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000411,,,,,,,,,,,,,,,,"pa_branch (Alan, Randi, Kevin, Jay, Bjoern)",,
http://purl.obolibrary.org/obo/OBI_1110011,allergic reaction,,an allergic reaction is an pathologic immune response by an organism to a non-self entity that is normally harmless(the allergen),false,,,http://purl.obolibrary.org/obo/OBI_1110122,,,,,,,,,,,,,,,,,,,an allergic reaction is an pathologic immune response by an organism to a non-self entity that is normally harmless(the allergen),IEDB,,,,,,allergic reaction,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110011,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,allergic reaction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_1110010,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0400120,temperature control bath,,"A temperature_control_bath is a device that has the function to regulate the temperature of a material, the function to contain fluid and the function to vary and maintain the temperature of the contained fluid. Heat exchange (energy transfer) between the material and the heating element is facilitated via the contained fluid. A temperature_control_bath is composed of a container, a heating element and/or a cooling element and a means to adjust the needed temperature. In most cases also a timer and a means to stir the fluid is provided as well.",false,,,http://purl.obolibrary.org/obo/OBI_0000967|http://purl.obolibrary.org/obo/OBI_0001034,,,,,,,,,,,,,,,,,DS: This was heated_bath. It was renamed to reflect the possability that the same bath can be used for cooling. We can now define the temperature variables and based on that infer if it is a cooling device or a heating device (also quite relative to surrounding temperature).,,"A temperature_control_bath is a device that has the function to regulate the temperature of a material, the function to contain fluid and the function to vary and maintain the temperature of the contained fluid. Heat exchange (energy transfer) between the material and the heating element is facilitated via the contained fluid. A temperature_control_bath is composed of a container, a heating element and/or a cooling element and a means to adjust the needed temperature. In most cases also a timer and a means to stir the fluid is provided as well.",OBI Instrument branch,,,,,,temperature control bath,,VWR Signature Deep-Chamber Heated Water Bath. A water bath is used for temperatures up to 100 degrees C. An oil bath is employed for temperatures over 100 degrees C.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000370|http://purl.obolibrary.org/obo/OBI_0000401,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,temperature control bath,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Daniel Schober|Alan Ruttenburg|Frank Gibson,,
http://purl.obolibrary.org/obo/OBI_0400034,dye laser,,"A dye laser is a laser in which the lasing medium is a fluorescent dye, usually dissolved in an organic solvent such as ethanol or ethylene glycol. The particular dye used determines the wavelengths the laser can emit. The laser medium is places between two parallel mirrors for light emission amplification.",false,,,http://purl.obolibrary.org/obo/OBI_0400064,,,,,,,,,,,,,,,,,,,"A dye laser is a laser in which the lasing medium is a fluorescent dye, usually dissolved in an organic solvent such as ethanol or ethylene glycol. The particular dye used determines the wavelengths the laser can emit. The laser medium is places between two parallel mirrors for light emission amplification.","Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253|John Quinn",,,,,,dye laser,,Rhodamine 101 dye laser used to irradiate cells in a flow cytometer.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400034,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,dye laser,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000933,positron emission tomography scanner,PET scanner?,"A device that produces a three-dimensional image or picture of functional processes in the body. It detects pairs of gamma rays emitted indirectly by a positron-emitting
radionuclide (tracer), which is introduced into the body on a biologically active molecule.",false,,,http://purl.obolibrary.org/obo/OBI_0000398,,,,PET scanner?,,,,,,,,,,,,,,,"A device that produces a three-dimensional image or picture of functional processes in the body. It detects pairs of gamma rays emitted indirectly by a positron-emitting
radionuclide (tracer), which is introduced into the body on a biologically active molecule.",http://en.wikipedia.org/wiki/Positron_emission_tomography,,,,,,positron emission tomography scanner,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000397,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000933,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,positron emission tomography scanner,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001117,DNA extraction/purification instrument,,A device that is used to isolate and collect DNA for subsequent molecular analysis.,false,,,http://purl.obolibrary.org/obo/OBI_0001114,,,,,,,,,,,,,,,,,,,A device that is used to isolate and collect DNA for subsequent molecular analysis.,http://en.wikipedia.org/wiki/DNA_extraction,,,,,,DNA extraction/purification instrument,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001117,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNA extraction/purification instrument,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001935,predicted mass value,, A predicted value where the prediction specifies the mass of some thing.,false,,,http://purl.obolibrary.org/obo/OBI_0001934,,,,,,,,,,,,,,,,,,, A predicted value where the prediction specifies the mass of some thing.,,,,,,,predicted mass value,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001935,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,predicted mass value,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Bjoern Peters,,
http://purl.obolibrary.org/obo/GO_0042101,T cell receptor complex,,"A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains.",false,,,http://purl.obolibrary.org/obo/OBI_1110022,,,,,,,,,,,,,,,,,,,"A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains.",,,,,,,T cell receptor complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0042101,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,T cell receptor complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000268,organism feature identification objective,,"Organism_feature_identification_objective is a biological_feature_identification_objective role describing a study designed to examine or characterize a biological feature monitored at the level of the organism, e.g. height, weight, stage of development, stage of life cycle.",false,,,http://purl.obolibrary.org/obo/OBI_0000015,,,,,,,,,,,,,,,,,,,"Organism_feature_identification_objective is a biological_feature_identification_objective role describing a study designed to examine or characterize a biological feature monitored at the level of the organism, e.g. height, weight, stage of development, stage of life cycle.",,,,,,,organism feature identification objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000268,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,organism feature identification objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel,,
http://purl.obolibrary.org/obo/GO_0072535,tumor necrosis factor (ligand) superfamily member 11 production,,"The appearance of tumor necrosis factor superfamily member 11 (TNFSF11; RANKL) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0071706,,,,,,,,,,,,,,,,,,,"The appearance of tumor necrosis factor superfamily member 11 (TNFSF11; RANKL) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,tumor necrosis factor (ligand) superfamily member 11 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0072535,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,tumor necrosis factor (ligand) superfamily member 11 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000492,Bruker B-ACS system,,"The Bruker Automatic Sample Changer (B-ACS 60/120), used in conjunction with Bruker DISNMR, UXNMR or XWIN-NMR software, provides dialog-guided facilities which allow the user to easily and effectively perform automatic (continuous) experiments. Features include a 60 or 120 sample capacity, random accessing of samples, positive sample identification with the optional bar code reader, and temperature control of individual samples with the optional sample heater unit.",false,,,http://purl.obolibrary.org/obo/OBI_0000464,,,,,,,,,,,,,,,,,NMR instrument,,"The Bruker Automatic Sample Changer (B-ACS 60/120), used in conjunction with Bruker DISNMR, UXNMR or XWIN-NMR software, provides dialog-guided facilities which allow the user to easily and effectively perform automatic (continuous) experiments. Features include a 60 or 120 sample capacity, random accessing of samples, positive sample identification with the optional bar code reader, and temperature control of individual samples with the optional sample heater unit.",WEB:<http://www.bruker-biospin.com/automation.html>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400210,,,,,,Bruker B-ACS system,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000492,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker B-ACS system,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001809,biological activity assay measuring epitope specific granzyme A release by T cells,granzyme A release|biological activity,A T cell epitope specific cytotoxic T cell degranulation assay that detects granzyme A release by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_0001269,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytotoxic T cell degranulation assay that detects granzyme A release by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific granzyme A release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001809,,,,,,,,,,,,,,,,,,,,,,,,granzyme A release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific granzyme A release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001148,gene knock out,,"a genetic transformation that renders a gene non-functional, e.g. due to a point mutation, or the removal of all, or part of, the gene using recombinant methods.",false,,,http://purl.obolibrary.org/obo/OBI_0600043,,,,,,,,,,,,,,,,,,,"a genetic transformation that renders a gene non-functional, e.g. due to a point mutation, or the removal of all, or part of, the gene using recombinant methods.",MO_771 gene_knock_out,,,,,,gene knock out,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001148,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,gene knock out,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000628,carbon nanotube column,,"Carbon nanotubes (CNTs) are known to have high thermal and mechanical stability and have the potential to be high-performance separation media that utilize the nanoscale interactions. CNT can be applied in long capillary tubes for the development of gas chromatography columns. A film of CNTs can be deposited by chemical vapor deposition (CVD) to form the stationary phase in the open tubular format. Altering the CVD conditions can vary the thickness and the morphology of the CNT film, which opens the possibility of selectivity tuning. The ability to fabricate long tubes coated with CNTs can be readily employed in other gas- and liquid-phase separations as well.",false,,,http://purl.obolibrary.org/obo/OBI_0000038,,,,,,,,,,,,,,,,,,,"Carbon nanotubes (CNTs) are known to have high thermal and mechanical stability and have the potential to be high-performance separation media that utilize the nanoscale interactions. CNT can be applied in long capillary tubes for the development of gas chromatography columns. A film of CNTs can be deposited by chemical vapor deposition (CVD) to form the stationary phase in the open tubular format. Altering the CVD conditions can vary the thickness and the morphology of the CNT film, which opens the possibility of selectivity tuning. The ability to fabricate long tubes coated with CNTs can be readily employed in other gas- and liquid-phase separations as well.",WEB:<http://pubs.acs.org/cgi-bin/abstract.cgi/ancham/2005/77/i21/abs/ac050812j.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01107,,,,,,carbon nanotube column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000628,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,carbon nanotube column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000809,amplified DNA,,DNA that has been produced in an enzymatic amplification process,false,,,http://purl.obolibrary.org/obo/CHEBI_16991|http://purl.obolibrary.org/obo/OBI_0000047,,,,,,,,,,,,,,,,,,,DNA that has been produced in an enzymatic amplification process,Alan Ruttenberg,,,,,,amplified DNA,,Amplied DNA  created by PCR,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000809,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,amplified DNA,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0000070,assay,measuring|scientific observation|any method|study assay,"A planned process with the objective to produce information about the material entity that is the evaluant, by physically examining it or its proxies.",false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,measuring|scientific observation,,,,,,,,,,,,,,,"A planned process with the objective to produce information about the material entity that is the evaluant, by physically examining it or its proxies.",OBI branch derived,,,,,"12/3/12: BP: the reference to the 'physical examination' is included to point out that a prediction is not an assay, as that does not require physical examiniation. ",assay,,Assay the wavelength of light emitted by excited Neon atoms. Count of geese flying over a house.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000070,,,,,,,,,,,,,,,,,,,,,,,,any method,,,,,,,,,,,,,,,,,,,,,study assay,assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000067,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0000016,regulation-assigned role,,Regulation-assigned role is a regulatory role defined by legislation or governmental orders,false,,,http://purl.obolibrary.org/obo/OBI_0000017,,,,,,,,,,,,,,,,,,,Regulation-assigned role is a regulatory role defined by legislation or governmental orders,,,,,,,regulation-assigned role,,Approval letter,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000016,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,regulation-assigned role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jennifer Fostel,,
http://purl.obolibrary.org/obo/BFO_0000018,zero-dimensional spatial region,,,false,,,http://purl.obolibrary.org/obo/BFO_0000006,,,,,,,ZeroDimensionalSpatialRegion,0d-s-region,,,,,,,,,,,,,,,,,,zero-dimensional spatial region,A zero-dimensional spatial region is a point in space. (axiom label in BFO2 Reference: [037-001]),,,,,,,,,(forall (x) (if (ZeroDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [037-001] ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000018,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,zero-dimensional spatial region,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001442,q-value,FDR adjusted p-value,"A quantitative confidence value that measures the minimum false discovery rate that is incurred when calling that test significant. 
To compute q-values, it is necessary to know the p-value produced by a test and possibly set a false discovery rate level.",false,,,http://purl.obolibrary.org/obo/OBI_0000071,,,,FDR adjusted p-value,,,,,,,,,,,,,,,"A quantitative confidence value that measures the minimum false discovery rate that is incurred when calling that test significant. 
To compute q-values, it is necessary to know the p-value produced by a test and possibly set a false discovery rate level.","Adapted from several sources, including
http://.en/wikipedia.org/wiki/False_discovery_rate
http://svitsrv25.epfl.ch/R-doc/library/qvalue.html",,,,,,q-value,,"PMID: 20483222. Comp Biochem Physiol Part D Genomics Proteomics. 2008 Sep;3(3):234-42. Analysis of Sus scrofa liver proteome and identification of proteins differentially expressed between genders, and conventional and genetically enhanced lines.
""After controlling the false discovery rate (FDR</=0.1) using the Storey q value only four proteins (EPHX1, CAT, PAH, ST13) were shown to be differentially expressed between genders (Males/Females) and two proteins (SELENBP2, TAGLN) were differentially expressed between two lines (Transgenic/Conventional pigs)""",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001442,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,q-value,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERS:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001980,in vivo intervention experiment,,An assay in which the effect of a targeted process (the intervention) on an organism is tested.,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,An assay in which the effect of a targeted process (the intervention) on an organism is tested.,IEDB,,,,,"The intervention in an experiment should be modeled accordingly to the intevention carried out in a human cllinical trial, which is currently modeled as 'study intervention'. This touches the boundaries of study vs. assay.",in vivo intervention experiment,,Comparing the level of allergy symptoms in humans before and post allergy immunotherapy. Testing if injection of a chemical compound into mice will lead to decreased survival.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001980,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,in vivo intervention experiment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000380,gas filter function,,"A gas filter function is a filter function which prevents the flow of solid objects, defined by specific qualities, in a gas-solid mixture",false,,,http://purl.obolibrary.org/obo/OBI_0000378,,,,,,,,,,,,,,,,,,,"A gas filter function is a filter function which prevents the flow of solid objects, defined by specific qualities, in a gas-solid mixture",,,,,,,gas filter function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000380,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,gas filter function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Frank Gibson,,
http://purl.obolibrary.org/obo/OBI_0200175,class discovery data transformation,unsupervised classification data transformation|clustering data transformation,A class discovery data transformation (sometimes called unsupervised classification) is a data transformation that has objective class discovery.,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,unsupervised classification data transformation|clustering data transformation,,,,,,,,,,,,,,,A class discovery data transformation (sometimes called unsupervised classification) is a data transformation that has objective class discovery.,PERSON: James Malone,,,,,,class discovery data transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200175,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,class discovery data transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0001413,cell culture analyte detection bioassay measuring epitope specific interleukin-6 production by T cells,IL-6 release|bioassay,An assay of epitope specific interleukin-6 production by T cells that uses a cell culture analyte detection bioassay.,false,,,http://purl.obolibrary.org/obo/OBI_0001451,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-6 production by T cells that uses a cell culture analyte detection bioassay.,IEDB,,,,,,cell culture analyte detection bioassay measuring epitope specific interleukin-6 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001413,,,,,,,,,,,,,,,,,,,,,,,,IL-6 release|bioassay,,,,,,,,,,,,,,,,,,,,,,cell culture analyte detection bioassay measuring epitope specific interleukin-6 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/GO_0035944,perforin production,,"The appearance of a perforin protein due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,"The appearance of a perforin protein due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,perforin production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0035944,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,perforin production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000553,Bruker Capillary LC-NMR platform,,"Capillary LC-NMR is a hyphenated technique coupling capillary liquid chromatography and NMR, which increases sensitivity dramatically through the use of miniaturization of the chromatographic techniques and NMR detection volume. LC-NMR hyphenated systems separate a mixture into its pure components and couple the output to NMR for automatic sample analysis. The ever increasing need to measure lower sample amounts and lower level impurities demands the highest NMR sensitivity. Traditional LC-NMR systems with relatively large peak volumes are not optimized for such low levels of detection. Bruker BioSpin, together with Waters and Protasis has developed a Capillary LC-NMR system. The latest capillary LC attributes and highest capillary flow probe sensitivity combine with state of the art NMR systems technology. Greater mass sensitivity and faster spectral analysis with smaller sample volumes is possible. This system is ideal for analysis of metabolites and impurities associated with the drug development process.",false,,,http://purl.obolibrary.org/obo/OBI_0000596,,,,,,,,,,,,,,,,,NMR instrument|hyphenated NMR instrument platform,,"Capillary LC-NMR is a hyphenated technique coupling capillary liquid chromatography and NMR, which increases sensitivity dramatically through the use of miniaturization of the chromatographic techniques and NMR detection volume. LC-NMR hyphenated systems separate a mixture into its pure components and couple the output to NMR for automatic sample analysis. The ever increasing need to measure lower sample amounts and lower level impurities demands the highest NMR sensitivity. Traditional LC-NMR systems with relatively large peak volumes are not optimized for such low levels of detection. Bruker BioSpin, together with Waters and Protasis has developed a Capillary LC-NMR system. The latest capillary LC attributes and highest capillary flow probe sensitivity combine with state of the art NMR systems technology. Greater mass sensitivity and faster spectral analysis with smaller sample volumes is possible. This system is ideal for analysis of metabolites and impurities associated with the drug development process.",WEB:<http://www.bruker-biospin.com/hyphenation_caplcnmr.html>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400279,,,,,,Bruker Capillary LC-NMR platform,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000553,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker Capillary LC-NMR platform,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001202,innate behavior design,,"A study design in which the innate behavior of the organism is examined, e.g. path finding in bees.",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A study design in which the innate behavior of the organism is examined, e.g. path finding in bees.",MO_355 innate_behavior_design,,,,,,innate behavior design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000268,,,,,,,,,,,,,,,,OBI:0001202,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,innate behavior design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001068,SPECT scanner,,"A nuclear medicine tomographic imaging device that uses gamma rays to provide 3D information, typically presented as cross-sectional slices through the specimen but with the ability to be freely reformatted or manipulated as required.",false,,,http://purl.obolibrary.org/obo/OBI_0000398,,,,,,,,,,,,,,,,,,,"A nuclear medicine tomographic imaging device that uses gamma rays to provide 3D information, typically presented as cross-sectional slices through the specimen but with the ability to be freely reformatted or manipulated as required.",http://en.wikipedia.org/wiki/Single_photon_emission_computed_tomography,,,,,,SPECT scanner,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453|http://purl.obolibrary.org/obo/OBI_0000397,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001068,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,SPECT scanner,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/GO_0006909,phagocytosis,,"An endocytosis process that results in the engulfment of external particulate material by phagocytes. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.",false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,"An endocytosis process that results in the engulfment of external particulate material by phagocytes. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.",,,,,,,phagocytosis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0006909,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,phagocytosis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000926,obsolete_ambidexterious handedness,,,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_ambidexterious handedness,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,OBI:0000926,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_ambidexterious handedness,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001730,surface plasmon resonance assay measuring the association constant [KA] of a B cell epitope:antibody complex,association constant KA|surface plasmon resonance (SPR)|1/nM,A B cell epitope equilibrium association constant (KA) determination assay that uses a surface plasmon resonance assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001719,,,,,,,,,,,,,,,,,,,A B cell epitope equilibrium association constant (KA) determination assay that uses a surface plasmon resonance assay.,IEDB,,,,,,surface plasmon resonance assay measuring the association constant [KA] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001730,,,,,,,,,,,,,,,,,,,,,,,,association constant KA|surface plasmon resonance (SPR)|1/nM,,,,,,,,,,,,,,,,,,,,,,surface plasmon resonance assay measuring the association constant [KA] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000288,protein-protein interaction detection,,"An assay with the objective to determine interactions between proteins, such as protein-protein binding.",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,"An assay with the objective to determine interactions between proteins, such as protein-protein binding.",,,,,,"20091101, Bjoern Peters: This class may be overly broad. Lot's of assays would seem to classify under it, and I have the feeling that the intend would be to limit this to determining protein-protein interactions as they occur within an organism, rather than e.g. peptide:MHC binding assays.",protein-protein interaction detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000288,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,protein-protein interaction detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001589,intracellular cytokine staining assay measuring epitope specific interleukin-17A production by T cells,IL-17A release|ICS,A T cell epitope specific interleukin-17A production assay that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001773|http://purl.obolibrary.org/obo/OBI_1110178,,,,,,,,,,,,,,,,,,,A T cell epitope specific interleukin-17A production assay that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-17A production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001589,,,,,,,,,,,,,,,,,,,,,,,,IL-17A release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-17A production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000784,anticoagulant-containing test tube,,A 'blue top' test tube that contains anticoagulant for storing blood specimens',false,,,http://purl.obolibrary.org/obo/OBI_0000836,,,,,,,,,,,,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,,A 'blue top' test tube that contains anticoagulant for storing blood specimens',,,,,,,anticoagulant-containing test tube,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000784,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,anticoagulant-containing test tube,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0000425,averaging objective,,An averaging objective is a data transformation objective where the aim is to perform mean calculations on the input of the data transformation.,false,,,http://purl.obolibrary.org/obo/OBI_0200166,,,,,,,,,,,,,,,,,,,An averaging objective is a data transformation objective where the aim is to perform mean calculations on the input of the data transformation.,PERSON: Elisabetta Manduchi,,,,,,averaging objective,,A mean calculation which has averaging objective is a descriptive statistics calculation in which the mean is calculated by taking the sum of all of the observations in a data set divided by the total number of observations. It gives a measure of the 'center of gravity' for the data set. It is also known as the first moment.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000425,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,averaging objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0000847,test substance role,,A role born by a material entity and realized in a process where the substance is used as specified as the independent variable for an investigation,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,,,A role born by a material entity and realized in a process where the substance is used as specified as the independent variable for an investigation,Group:OBI,,,,,,test substance role,,fucoidan bears a test substance role in a study to test safety taking a certain dosage of it orally,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000847,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,test substance role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0001700,immunoprecipitation assay,,"An analyte assay in which an input material is mixed with antibodies and bound antigen:antibody complexes are separated out using immunoprecipitation. Either the antibody has known specificy, and the antigen mixture is tested for the presence of a specific antigen, or the antigen solution is well defined and the antibody solution is tested for the presence of antigen specific antibodies.",false,,,http://purl.obolibrary.org/obo/OBI_0000443,,,,,,,,,,,,,,,,,,,"An analyte assay in which an input material is mixed with antibodies and bound antigen:antibody complexes are separated out using immunoprecipitation. Either the antibody has known specificy, and the antigen mixture is tested for the presence of a specific antigen, or the antigen solution is well defined and the antibody solution is tested for the presence of antigen specific antibodies.",IEDB,,,,,,immunoprecipitation assay,,Determining if a cell is producing a protein using a protein specific antibody to immunoprecipitate the cell lysate. Determining if the serum of a patient contains antibodies against HBV core protein by immunoprecipitating purified HBV core protein with the patients serum.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001700,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,immunoprecipitation assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001994,assay measuring the MHC ligand binding on rate [kon] of a MHC:ligand complex,on rate|binding assay|nM^-1s^-1,A MHC binding constant determination assay measuring binding on rate (kon).,false,,,http://purl.obolibrary.org/obo/OBI_0001553,,,,,,,,,,,,,,,,,,,A MHC binding constant determination assay measuring binding on rate (kon).,IEDB,,,,,,assay measuring the MHC ligand binding on rate [kon] of a MHC:ligand complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001994,,,,,,,,,,,,,,,,,,,,,,,,on rate|binding assay|nM^-1s^-1,,,,,,,,,,,,,,,,,,,,,,assay measuring the MHC ligand binding on rate [kon] of a MHC:ligand complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000856,obsolete intracellular material detection by flow cytometry assay,intracellular staining,"An assay in which the presence of a material inside a cell is measured by permeabilizing the cell membrane to allow entry of specific antibodies, and counting the stained cells using a flow cytometer.",true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,"An assay in which the presence of a material inside a cell is measured by permeabilizing the cell membrane to allow entry of specific antibodies, and counting the stained cells using a flow cytometer.",,,,,,,obsolete intracellular material detection by flow cytometry assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000227,,,,,,,,,,,,,,,,,,OBI:0000856,,,,,,,,,,,,,,,,,,,,,,,,intracellular staining,,,,,,,,,,,,,,,,,,,,,,obsolete intracellular material detection by flow cytometry assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000916,
http://purl.obolibrary.org/obo/OBI_0600043,genetic transformation,genetic modification,the introduction. alteration or integration of genetic material into a cell or organism,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0001153,,genetic modification,,,,,,,,,,,,,,,the introduction. alteration or integration of genetic material into a cell or organism,OBI branch derived,,,,,,genetic transformation,,The transduction of E. coli through the introduction of a plasmid encoding for M. avium p35,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001151,,,OBI:0600043,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,genetic transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Kevin Clancy,,
http://purl.obolibrary.org/obo/OBI_1110014,epitope binding by adaptive immune receptor,,"is the process in which an adaptive immune receptor binds to a material entity (realizing its disposition). The binding affinity is significant enough to trigger an immune response. Specifically, transient non-specific binding of adaptive immune receptors occurring during immune surveillance is not considered significant binding.",false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,"is the process in which an adaptive immune receptor binds to a material entity (realizing its disposition). The binding affinity is significant enough to trigger an immune response. Specifically, transient non-specific binding of adaptive immune receptors occurring during immune surveillance is not considered significant binding.",IEDB,,,,,,epitope binding by adaptive immune receptor,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110014,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope binding by adaptive immune receptor,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000596,Bruker NMR instrument,,An NMR instrument that is manufactured by Bruker.,false,,,http://purl.obolibrary.org/obo/OBI_0000566,,,,,,,,,,,,,,,,,NMR instrument,,An NMR instrument that is manufactured by Bruker.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400198,,,,,,Bruker NMR instrument,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000596,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker NMR instrument,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001891,sequencing facility organization,Sequencing Facility,An organization that provides sequence determination service,false,,,http://purl.obolibrary.org/obo/OBI_0000245,,,,,,,,,,,,,,,,,,,An organization that provides sequence determination service,NIAID GSCID-BRC metadata working group,,,,,,sequencing facility organization,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001891,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sequencing facility organization,,,,,,Sequencing Facility,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0302846,randomized group participant role,,a role that borne by an organism and realized by some group randomization process,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,,,a role that borne by an organism and realized by some group randomization process,,,,,,,randomized group participant role,,A person enrolled in a randomized clinical trial bears a randomized group participant role,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302846,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,randomized group participant role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Helen Parkinson|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001489,mass spectrometry assay measuring MHC ligand processing and presentation of MHC ligands eluted from cellular MHC,ligand presentation|cellular MHC/mass spectrometry,A mass spectrometry of MHC ligands assay that identifies eluted ligands from cell bound MHC.,false,,,http://purl.obolibrary.org/obo/OBI_0001478,,,,,,,,,,,,,,,,,,,A mass spectrometry of MHC ligands assay that identifies eluted ligands from cell bound MHC.,IEDB,,,,,,mass spectrometry assay measuring MHC ligand processing and presentation of MHC ligands eluted from cellular MHC,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000470,,,,,,,,,,,,,,,,OBI:0001489,,,,,,,,,,,,,,,,,,,,,,,,ligand presentation|cellular MHC/mass spectrometry,,,,,,,,,,,,,,,,,,,,,,mass spectrometry assay measuring MHC ligand processing and presentation of MHC ligands eluted from cellular MHC,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000041,pump valve switch,,A pump valve switch is a cardinal part of a liquid chromatography instrument that controls the flow.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A pump valve switch is a cardinal part of a liquid chromatography instrument that controls the flow.,OBI,,,,,FG:I would assume this should be a pump valve control switch and it would not be specific to a liquid chromatography instrument,pump valve switch,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000379,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000041,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,pump valve switch,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI Instrument branch,,
http://purl.obolibrary.org/obo/OBI_0600047,sequencing assay,,the use of a chemical or biochemical means to infer the sequence of a biomaterial,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,the use of a chemical or biochemical means to infer the sequence of a biomaterial,OBI branch derived,,,,,has_output should be sequence of input; we don't have sequence well defined yet,sequencing assay,,The use of the Sanger method of DNA sequencing to determine the order of the nucleotides in a DNA template,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600047,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sequencing assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0001462,epitope specific IP-10 production by T cells,,A process of IP-10 production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0071612|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of IP-10 production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific IP-10 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001462,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific IP-10 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000274,adding a material entity into a target,,is a process with the objective to place a material entity bearing the 'material to be added role' into a material bearing the 'target of material addition role'.,false,,,http://purl.obolibrary.org/obo/OBI_0000652,,,,,,,,,,,,,,,,,,,is a process with the objective to place a material entity bearing the 'material to be added role' into a material bearing the 'target of material addition role'.,branch derived,,,,,"Class was renamed from 'administering substance', as this is commonly used only for additions into organisms.",adding a material entity into a target,,Injecting a drug into a mouse. Adding IL-2 to a cell culture. Adding NaCl into water.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000274,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,adding a material entity into a target,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000319|http://purl.obolibrary.org/obo/OBI_0000444,,,,,,,,,,,,,,,,BP,,
http://purl.obolibrary.org/obo/OBI_0001513,purified MHC competitive binding assay of a MHC:ligand complex using radioactivity detection,qualitative binding|purified MHC/competitive/radioactivity,A purified MHC binding assay that uses radioactivity detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation.,false,,,http://purl.obolibrary.org/obo/OBI_0001555|http://purl.obolibrary.org/obo/OBI_0001491,,,,,,,,,,,,,,,,,,,A purified MHC binding assay that uses radioactivity detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation.,IEDB,,,,,,purified MHC competitive binding assay of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000201,,,,,,,,,,,,,,,,OBI:0001513,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|purified MHC/competitive/radioactivity,,,,,,,,,,,,,,,,,,,,,,purified MHC competitive binding assay of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0200182,data vector reduction data transformation,,"A data vector reduction is a data transformation that has objective data vector reduction and that consists of reducing the input vectors k to a smaller number of output vectors j, where j<k.",false,,,http://purl.obolibrary.org/obo/OBI_0000707,,,,,,,,,,,,,,,,,,,"A data vector reduction is a data transformation that has objective data vector reduction and that consists of reducing the input vectors k to a smaller number of output vectors j, where j<k.",PERSON: James Malone,,,,,,data vector reduction data transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200182,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,data vector reduction data transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_1110171,ELISPOT assay measuring epitope specific interleukin-13 production by T cells,IL-13 release|ELISPOT,An assay of epitope specific interleukin-13 production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001251,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-13 production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific interleukin-13 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110171,,,,,,,,,,,,,,,,,,,,,,,,IL-13 release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific interleukin-13 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001181,binding datum,,"A data item that states if two or more material entities have the disposition to form a complex, and if so, how strong that disposition is. ",false,,,http://purl.obolibrary.org/obo/IAO_0000027,,,,,,,,,,,,,,,,,,,"A data item that states if two or more material entities have the disposition to form a complex, and if so, how strong that disposition is. ",,,,,,,binding datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001181,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,binding datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters; Randi Vita,,
http://purl.obolibrary.org/obo/PATO_0001995,organismal quality,,A quality that inheres in an entire organism or part of an organism.,false,,,http://purl.obolibrary.org/obo/BFO_0000019,,,,,,,,,,,,,,,,,,,A quality that inheres in an entire organism or part of an organism.,,,,,,,organismal quality,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001995,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,organismal quality,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001557,material storage service,,A storage service in which a service consumer provides some material as input which a service provider stores and returns as output.,false,,,http://purl.obolibrary.org/obo/OBI_0001528|http://purl.obolibrary.org/obo/OBI_0001515,,,,,,,,,,,,,,,,,,,A storage service in which a service consumer provides some material as input which a service provider stores and returns as output.,PERSON: Matthew Brush,,,,,,material storage service,,A service that offers liquid nitrogen stroage.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001557,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,material storage service,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Carlo Torniai|PERSON: Matthew Brush,,
http://purl.obolibrary.org/obo/IAO_0000102,data about an ontology part,,"data about an ontology part is a data item about a part of an ontology, for example a term",false,,,http://purl.obolibrary.org/obo/IAO_0000027,,,,,,,,,,,,,,,,,,,"data about an ontology part is a data item about a part of an ontology, for example a term",,,,,,,data about an ontology part,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000102,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,data about an ontology part,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://www.w3.org/2002/07/owl#Nothing,Nothing,,,false,,,http://www.w3.org/2002/07/owl#Nothing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,owl:Nothing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0002032,parallel analysis of RNA structure,PARS,"A single-nucleotide-resolution nucleic acid structure mapping assay using enzymatic probing based on deep sequencing fragments of RNAs that were treated with structure-specific enzymes, thus providing simultaneous in vitro profiling of the secondary structure of thousands of RNA species at single nucleotide resolution.",false,,,http://purl.obolibrary.org/obo/OBI_0001014,,,,PARS,,,,,,,,,,,,,,,"A single-nucleotide-resolution nucleic acid structure mapping assay using enzymatic probing based on deep sequencing fragments of RNAs that were treated with structure-specific enzymes, thus providing simultaneous in vitro profiling of the secondary structure of thousands of RNA species at single nucleotide resolution.",pmid:20811459,,,,,Details see tracker: https://sourceforge.net/p/obi/obi-terms/725/,parallel analysis of RNA structure,,pmid:20811459,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002032,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,parallel analysis of RNA structure,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Saccharomyces Genome Database (SGD),,,,,,,,"Janos Demeter, Chris Stoeckert",,
http://purl.obolibrary.org/obo/OBI_1110030,experimental infection of cell culture,,is the administration of an infectious agent to a cell culture with the objective to have the agent colonize and replicate in culture,false,,,http://purl.obolibrary.org/obo/OBI_0600000,,,,,,,,,,,,,,,,,,,is the administration of an infectious agent to a cell culture with the objective to have the agent colonize and replicate in culture,IEDB,,,,,,experimental infection of cell culture,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110030,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,experimental infection of cell culture,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001752,detection of specific nucleic acids with complementary probes assay measuring epitope specific granulocyte colony stimulating factor production by T cells,G-CSF release|RNA/DNA detection,An assay of epitope specific granulocyte colony stimulating factor production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001600,,,,,,,,,,,,,,,,,,,An assay of epitope specific granulocyte colony stimulating factor production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific granulocyte colony stimulating factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001752,,,,,,,,,,,,,,,,,,,,,,,,G-CSF release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific granulocyte colony stimulating factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_1110108,material to be added,,a material that is added to another one in a material combination process,false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,a material that is added to another one in a material combination process,IEDB,,,,,"2010/02/24  Alan Ruttenberg: I think this might generate confusion as the common use of the term would consider something to be a specimen during the realization of the role, not only if it bears it. However having this class as a probe, or for display, or as a macro might be useful. Ideally we would mark or segregate such classes|10/26/09: This defined class is used as a 'macro expression' to reduce the  size of the IEDB export",material to be added,,A mixture of peptides that is being added into a cell culture.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110108,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,material to be added,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000791,multiple testing correction objective,multiple comparison correction objective,A multiple testing correction objectives is a data transformation objective where the aim is to correct for a set of statistical inferences considered simultaneously,false,,,http://purl.obolibrary.org/obo/OBI_0200186,,,,multiple comparison correction objective,,,,,,,,,,,,,,,A multiple testing correction objectives is a data transformation objective where the aim is to correct for a set of statistical inferences considered simultaneously,http://en.wikipedia.org/wiki/Multiple_Testing_Correction,,,,,,multiple testing correction objective,,Application of the Bonferroni correction,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000791,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,multiple testing correction objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0302903,nucleic acid hybridization,hybridization assay,"a planned process by which totally or partially complementary, single-stranded nucleic acids are  combined into a single molecule called heteroduplex or homoduplex to an extent depending on the amount of complementarity.",false,,,http://purl.obolibrary.org/obo/OBI_0000094,,,,,,,,,,,,,,,,,,,"a planned process by which totally or partially complementary, single-stranded nucleic acids are  combined into a single molecule called heteroduplex or homoduplex to an extent depending on the amount of complementarity.",adapted from wikipedia [http://en.wikipedia.org/wiki/Nucleic_acid_hybridization],,,,,,nucleic acid hybridization,,PMID: 18555787.Quantitative analysis of DNA hybridization in a flowthrough microarray for molecular testing. Anal Biochem. 2008 May 27.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302903,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,hybridization assay,nucleic acid hybridization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0002080,human specimen set,,A specimen set that is collected from one person during a time period which for the purpose of the study can be considered to be taken at the same sampling time.,false,,,http://purl.obolibrary.org/obo/OBI_0002079,,,,,,,,,,,,,,,,,,,A specimen set that is collected from one person during a time period which for the purpose of the study can be considered to be taken at the same sampling time.,"Helena Ellis, Anna Maria Masci, OBIB, OBI",,,,,Details see tracker: https://sourceforge.net/p/obi/obi-terms/778/,human specimen set,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002080,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,human specimen set,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Biobank,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/IAO_0000329,running title,,A shorter version of a document title,false,,,http://purl.obolibrary.org/obo/IAO_0000305,,,,,,,,,,,,,,,,,,,A shorter version of a document title,,,,,,,running title,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000329,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,running title,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0100035,obsolete_immortal cell,,a cell derived from a multicellular organism that has the potential to replicate indefinitely,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,a cell derived from a multicellular organism that has the potential to replicate indefinitely,GROUP: OBI Biomaterial Branch,,,,,,obsolete_immortal cell,,a single Hela cell,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000228,,,,,,,,,,,,,,,,,,OBI:0100035,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_immortal cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters,http://purl.obolibrary.org/obo/CL_0000002,
http://purl.obolibrary.org/obo/OBI_0001750,intracellular cytokine staining assay measuring epitope specific granulocyte colony stimulating factor production by T cells,G-CSF release|ICS,An assay of epitope specific granulocyte colony stimulating factor production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001600,,,,,,,,,,,,,,,,,,,An assay of epitope specific granulocyte colony stimulating factor production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific granulocyte colony stimulating factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001750,,,,,,,,,,,,,,,,,,,,,,,,G-CSF release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific granulocyte colony stimulating factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0400029,CytoSub,,"A CytoSub is a flow_cytometer_analyser manufactured by Cyto Buoy Inc. They are a single laser, multi parameter instrument. Various types of micro-laser are offered; available measuring parameters are forward light scatter, side scatter, and fluorescence (max. 9 colour bands). The current series have 5 parameters. The CytoSub is the submersible version equipped with a high pressure sample inlet loop and a high pressure housing to allow underwater operation down to 200 m, lowered on a cable or mounted on a flooded underwater vehicle.",false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,,,,,,,,,,,,,,,,"A CytoSub is a flow_cytometer_analyser manufactured by Cyto Buoy Inc. They are a single laser, multi parameter instrument. Various types of micro-laser are offered; available measuring parameters are forward light scatter, side scatter, and fluorescence (max. 9 colour bands). The current series have 5 parameters. The CytoSub is the submersible version equipped with a high pressure sample inlet loop and a high pressure housing to allow underwater operation down to 200 m, lowered on a cable or mounted on a flooded underwater vehicle.",http://www.cytobuoy.com/,,,,,,CytoSub,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400029,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CytoSub,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0000433,DNA sequence feature detection,,An assay with the objective to determine a sequence feature of DNA,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,http://purl.obolibrary.org/obo/OBI_0000113|http://purl.obolibrary.org/obo/OBI_0000441,,,,,,,,,,,,,,,,,An assay with the objective to determine a sequence feature of DNA,OBI,,,,,should be a defined class where interpretation of data generated by assay qualifies a DNA sequence,DNA sequence feature detection,,genotyping using an Affymetrix chip,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_16991,http://purl.obolibrary.org/obo/IAO_0000109,,,OBI:0000433,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNA sequence feature detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra|Person:Bjoern Peters,,
http://purl.obolibrary.org/obo/NCBITaxon_40674,Mammalia,mammals,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_32524,,,,mammals,,,,,,,,,,,,,,,,,,,,,,Mammalia,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:40674,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Mammalia,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/NCBITaxon_314146,Euarchontoglires,,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_40674,,,,,,,,,,,,,,,,,,,,,,,,,,Euarchontoglires,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:314146,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Euarchontoglires,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000338,drawing a conclusion based on data,,A planned process in which data gathered in an investigation is evaluated in the context of existing knowledge with the objective to generate more general conclusions or to conclude that the data does not allow one to draw general conclusion,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,,,A planned process in which data gathered in an investigation is evaluated in the context of existing knowledge with the objective to generate more general conclusions or to conclude that the data does not allow one to draw general conclusion,Bjoern Peters,,,,,,drawing a conclusion based on data,,"Concluding that a gene is upregulated in a tissue sample based on the band intensity in a western blot.  Concluding that a patient has a infection based on measurement of an elevated body temperature and reported headache. Concluding that there were problems in an investigation because data from PCR and microarray are conflicting. Concluding that 'defects in gene XYZ cause cancer due to improper DNA repair' based on data from experiments in that study that gene XYZ is involved in DNA repair, and the conclusion of a previous study that cancer patients have an increased number of mutations in this gene. ",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000027,http://purl.obolibrary.org/obo/OBI_0001909,,,OBI:0000338,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,drawing a conclusion based on data,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Jennifer Fostel|PERSON: Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0400059,interrogation_point,,"Point within the fluidic subsystem at which the laser intersects the stream, illuminating the cells where they emit their fluorescence and scatter the light. The laser irradiates the cell at the interrogation point.",false,,,http://purl.obolibrary.org/obo/BFO_0000029,,,,,,,,,,,,,,,,,,,"Point within the fluidic subsystem at which the laser intersects the stream, illuminating the cells where they emit their fluorescence and scatter the light. The laser irradiates the cell at the interrogation point.","http://www.flocyte.com/FRTP/Resources/flow_cytometry_glossary.htm, 2007-05-11",,,,,,interrogation_point,,Interrogation point in BD FACS Calibur,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400059,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,interrogation_point,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_1110182,epitope specific T cell proliferation,,A biological process where T cells proliferate resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0042098,,,,,,,,,,,,,,,,,,,A biological process where T cells proliferate resulting from the recognition of a T cell epitope.,IEDB,,,,,,epitope specific T cell proliferation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110182,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific T cell proliferation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000413,cell cycle synchronization,,a process with the objective to obtain a cell culture in which all cells are in the same stage of the cell cycle,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,a process with the objective to obtain a cell culture in which all cells are in the same stage of the cell cycle,Bjoern Peters and Nicole Washington,,,,,,cell cycle synchronization,,Elimination of serum from the culture medium for about 24 hours results in the accumulation of cells at G1 phase. This effect of nutritional deprivation can be restored by their addition by which time the cell synchrony occurs.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100060,http://purl.obolibrary.org/obo/OBI_0100060,,,OBI:0000413,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cell cycle synchronization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI PA,,
http://purl.obolibrary.org/obo/OBI_0400088,quartz cuvette flow chamber,,A flow cell in which the laser irradiates the cell as it passes through a quartz cuvette. A quartz cuvette flow chamber can be used to allow the laser to irradiate cells.,false,,,http://purl.obolibrary.org/obo/OBI_0400043,,,,,,,,,,,,,,,,,,,A flow cell in which the laser irradiates the cell as it passes through a quartz cuvette. A quartz cuvette flow chamber can be used to allow the laser to irradiate cells.,http://www.flocyte.com/FRTP/Resources/flow_cytometry_glossary.htm,,,,,,quartz cuvette flow chamber,,"CVF-Q-10 flow chamber, CV-Q-10 flow chamber",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400088,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,quartz cuvette flow chamber,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0001473,in vivo assay measuring T cell epitope specific protection from tumor challenge,tumor burden after challenge|in vivo assay,A T cell epitope in vivo intervention experiment that uses a protection from challenge in vivo intervention experiment based on tumor burden.,false,,,http://purl.obolibrary.org/obo/OBI_0002073,,,,,,,,,,,,,,,,,,,A T cell epitope in vivo intervention experiment that uses a protection from challenge in vivo intervention experiment based on tumor burden.,IEDB,,,,,,in vivo assay measuring T cell epitope specific protection from tumor challenge,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001473,,,,,,,,,,,,,,,,,,,,,,,,tumor burden after challenge|in vivo assay,,,,,,,,,,,,,,,,,,,,,,in vivo assay measuring T cell epitope specific protection from tumor challenge,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000562,anion trap column,,An anion trap column is a trap column and ion-exchange column which contains cationic anion-exchange resins.,false,,,http://purl.obolibrary.org/obo/OBI_0000518,,,,,,,,,,,,,,,,,,,An anion trap column is a trap column and ion-exchange column which contains cationic anion-exchange resins.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01277,,,,,,anion trap column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000562,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,anion trap column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000385,ionization function,,An ionization function is a function to physically convert an atom or molecule into an ion by adding or removing charged particles such as electrons or other ions.,false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,An ionization function is a function to physically convert an atom or molecule into an ion by adding or removing charged particles such as electrons or other ions.,http://en.wikipedia.org/wiki/Ionization,,,,,,ionization function,,The ion source in amass spectrometer,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000385,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ionization function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bill Bug|Daniel Schober|Frank Gibson|Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0001185,selectively maintained organism,strain|cultivar|ecotype,"An organism that is bred to have some uniform behavioral, morphological, physiological, or genetic characteristics with similarly bred organisms",false,,,http://purl.obolibrary.org/obo/OBI_0100026,,,,strain|cultivar|ecotype,,,,,,,,,,,,,,,"An organism that is bred to have some uniform behavioral, morphological, physiological, or genetic characteristics with similarly bred organisms","MO_9 StrainOrLine, MO_71 Ecotype, MO_124 Cultivar",,,,,,selectively maintained organism,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001185,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,selectively maintained organism,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Bjoern Peters, Helen Parkinson, Philippe Rocca-Serra, Jie Zheng, Chris Stoeckert ",,
http://purl.obolibrary.org/obo/IAO_0000574,assigning a centrally registered identifier,assigning a CRID,"a planned process in which a new CRID is created, associated with an entity, and stored in the CRID registry thereby registering it as being associated with some entity",false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,assigning a CRID,,,,,,,,,,,,,,,"a planned process in which a new CRID is created, associated with an entity, and stored in the CRID registry thereby registering it as being associated with some entity",,,,,,"2014-05-05: It is the CRID registry that assigns CRIDs, not the users of the registry.",assigning a centrally registered identifier,,"A new pubmed ID being created for a journal article, and the associated pubmed record containing information to the journal article. A license plate number registered at the DMV to be belonging to a specific vehicle and owner. Placing a barcode on a product and entering information in a database that this barcode is assigned.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000579,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000577,,,IAO:0000574,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,assigning a centrally registered identifier,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Melanie Courtot|Person:Bjoern Peters|Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0500000,study design,experimental design,A plan specification comprised of protocols (which may specify how and what kinds of data will be gathered) that are executed as part of an investigation and is realized during a study design execution.,false,,,http://purl.obolibrary.org/obo/IAO_0000104,,,,experimental design,,,,,,,,,,,,,rediscussed at length (MC/JF/BP). 12/9/08). The definition was clarified to differentiate it from protocol.,,A plan specification comprised of protocols (which may specify how and what kinds of data will be gathered) that are executed as part of an investigation and is realized during a study design execution.,,,,,,Editor note: there is at least an implicit restriction on the kind of data transformations that can be done based on the measured data available.,study design,,"a matched pairs study design describes criteria by which subjects are identified as pairs which then undergo the same protocols, and the data generated is analyzed by comparing the differences between the paired subjects, which constitute the results of the executed study design.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000272,,,,,,,,,,,,,,,,OBI:0500000,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/obi.owl,,,,,,,,,,,,,,,,,,,study design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0001901,specimen identifier assigned by sequencing facility,Sample ID - Sequencing Facility,A specimen identifier which is assigned by a sequencing facility,false,,,http://purl.obolibrary.org/obo/OBI_0001616,,,,,,,,,,,,,,,,,,,A specimen identifier which is assigned by a sequencing facility,NIAID GSCID-BRC metadata working group,,,,,,specimen identifier assigned by sequencing facility,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001901,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,specimen identifier assigned by sequencing facility,,,,,,Sample ID - Sequencing Facility,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001534,purified MHC competitive binding assay measuring binding of a MHC:ligand complex using fluorescence detection,qualitative binding|purified MHC/competitive/fluorescence,A purified MHC binding assay that uses fluorescence detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation.,false,,,http://purl.obolibrary.org/obo/OBI_0001555|http://purl.obolibrary.org/obo/OBI_0001499,,,,,,,,,,,,,,,,,,,A purified MHC binding assay that uses fluorescence detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation.,IEDB,,,,,,purified MHC competitive binding assay measuring binding of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001501,,,,,,,,,,,,,,,,OBI:0001534,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|purified MHC/competitive/fluorescence,,,,,,,,,,,,,,,,,,,,,,purified MHC competitive binding assay measuring binding of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0200166,data transformation objective,,An objective specification to transformation input data into output data,false,,,http://purl.obolibrary.org/obo/IAO_0000005,,,,,,,,,,,,,,,,,,,An objective specification to transformation input data into output data,PERSON: James Malone,,,,,Modified definition in 2013 Philly OBI workshop,data transformation objective,,normalize objective,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200166,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,data transformation objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0000371,heat function,,A heat function is a function that increases the internal kinetic energy of a material,false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,A heat function is a function that increases the internal kinetic energy of a material,,,,,,,heat function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000371,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,heat function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bill Bug|Daniel Schober|Frank Gibson|Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0200108,eh transformation,,"An eh transformation is a data transformation obtained by applying the function EH described in what follows to a (one dimensional) real number input. EH(x)=exp(x*d/r)+b*(d/r)*x-1, if x>=0, and EH(x)=-exp(-x*d/r)+b*(d/r)*x+1, otherwise. Here exp denotes an exponential transformation and b, d, r are positive real constants with the objective of normalization.",false,,,http://purl.obolibrary.org/obo/OBI_0200169,,http://purl.obolibrary.org/obo/OBI_0200167,,,,,,,,,,,,,,,,,"An eh transformation is a data transformation obtained by applying the function EH described in what follows to a (one dimensional) real number input. EH(x)=exp(x*d/r)+b*(d/r)*x-1, if x>=0, and EH(x)=-exp(-x*d/r)+b*(d/r)*x+1, otherwise. Here exp denotes an exponential transformation and b, d, r are positive real constants with the objective of normalization.",WEB: http://flowcyt.sourceforge.net/gating/latest.pdf,,,,,,eh transformation,,This type of transformation is typically used in flow cytometry.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200108,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,eh transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Ryan Brinkman|Joseph Spliden|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0001430,transcription profiling design,,A study design that identifies forms and abundance of transcripts in the genome.,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,A study design that identifies forms and abundance of transcripts in the genome.,MO_533 transcript_identification_design,,,,,,transcription profiling design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001430,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,transcription profiling design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0100026,organism,,"A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs.",false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,"A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs.",WEB: http://en.wikipedia.org/wiki/Organism,,,,,"13-02-2009:
OBI doesn't take position as to  when an organism starts or ends being an organism - e.g. sperm, foetus.
This issue is outside the scope of OBI.|10/21/09: This is a placeholder term, that should ideally be imported from the NCBI taxonomy, but the high level hierarchy there does not suit our needs (includes plasmids and 'other organisms')",organism,,plant|animal|fungus|virus,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0100026,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,organism,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP: OBI Biomaterial Branch,,
http://purl.obolibrary.org/obo/OBI_0001647,NMR assay determining the 3D structure of a B cell epitope:antibody complex,3D structure|nuclear magnetic resonance (NMR),A B cell epitope 3D structure determination assay that uses a nuclear magnetic resonance assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001721,,,,,,,,,,,,,,,,,,,A B cell epitope 3D structure determination assay that uses a nuclear magnetic resonance assay.,IEDB,,,,,,NMR assay determining the 3D structure of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001647,,,,,,,,,,,,,,,,,,,,,,,,3D structure|nuclear magnetic resonance (NMR),,,,,,,,,,,,,,,,,,,,,,NMR assay determining the 3D structure of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0200129,node quality calculation,,A network analysis in which an input data set describing node objects and edge relationships between node objects is used to determine the output quality of one of the node objects in the network.,false,,,http://purl.obolibrary.org/obo/OBI_0200080,,,,,,,,,,,,,,,,,,,A network analysis in which an input data set describing node objects and edge relationships between node objects is used to determine the output quality of one of the node objects in the network.,PERSON: Richard Scheuermann,,,,,,node quality calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200129,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,node quality calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Richard Scheuermann,,
http://purl.obolibrary.org/obo/OBI_0001858,cross-linking immunoprecipitation high-throughput sequencing assay,CLIP-seq assay|CLIP-seq|HITS-CLIP,"An assay that employs UV-crosslinking between RNA and the protein, followed by immunoprecipitation with antibodies for the protein, fragmentation, and high-throughput used for screening for RNA sequences that interact with a particular RNA-binding protein.",false,,,http://purl.obolibrary.org/obo/OBI_0600047|http://purl.obolibrary.org/obo/OBI_0000443,,http://purl.obolibrary.org/obo/OBI_0000437|http://purl.obolibrary.org/obo/OBI_0001854,,CLIP-seq assay|CLIP-seq|HITS-CLIP,,,,,,,,,,,,,,,"An assay that employs UV-crosslinking between RNA and the protein, followed by immunoprecipitation with antibodies for the protein, fragmentation, and high-throughput used for screening for RNA sequences that interact with a particular RNA-binding protein.",Licatalosi et al. HITS-CLIP yields genome-wide insights into brain alternative RNA processing. Nature. 2008 Nov 27 456: 464-469 [PMID:18978773],,,,,,cross-linking immunoprecipitation high-throughput sequencing assay,,Heulga et al. Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins. Cell Rep. 2012 Feb 23;1(2):167-78. [PMID:22574288],,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000800|http://purl.obolibrary.org/obo/OBI_0001177|http://purl.obolibrary.org/obo/OBI_0000690|http://purl.obolibrary.org/obo/OBI_0000711,http://purl.obolibrary.org/obo/OBI_0400103|http://purl.obolibrary.org/obo/OBI_0400114,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001573,,,OBI:0001858,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cross-linking immunoprecipitation high-throughput sequencing assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001062,densitometer,,A device that measures the degree of darkness (the optical density) of a photographic or semitransparent material or of a reflecting surface.,false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,A device that measures the degree of darkness (the optical density) of a photographic or semitransparent material or of a reflecting surface.,http://en.wikipedia.org/wiki/Densitometer,,,,,,densitometer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001062,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,densitometer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001212,epitope specific type IV hypersensitivity by T cells,,A process of type IV hypersensitivity by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0001806,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of type IV hypersensitivity by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific type IV hypersensitivity by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001212,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific type IV hypersensitivity by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_1110207,assay detecting IFN-gamma production,IFNg release,an assay that determines information about the production of the cytokine interferon gamma,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,an assay that determines information about the production of the cytokine interferon gamma,IEDB,,,,,,assay detecting IFN-gamma production,,An IFN-g ELISPOT is an assay detecting ifn-gamma production,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110207,,,,,,,,,,,,,,,,,,,,,,,,IFNg release,,,,,,,,,,,,,,,,,,,,,,assay detecting IFN-gamma production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000468,protein column,,"A protein column is a chromatography column used for the separation of complex protein mixtures. Protein columns enable sample desalting, followed by chromatographic separation or fractionation of complex protein samples, e.g. immunodepleted serum or plasma proteins.",false,,,http://purl.obolibrary.org/obo/OBI_0000038,,,,,,,,,,,,,,,,,refactor as defined class,,"A protein column is a chromatography column used for the separation of complex protein mixtures. Protein columns enable sample desalting, followed by chromatographic separation or fractionation of complex protein samples, e.g. immunodepleted serum or plasma proteins.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01238,,,,,,protein column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000468,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,protein column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001684,methylation-specific polymerase chain reaction ,MSP,"is an assay which uses initial modification of DNA by sodium bisulfite, converting all unmethylated, but not methylated, cytosines to uracil, and subsequent amplification with primers specific for methylated versus unmethylated DNA.",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,MSP,,,,,,,,,,,,,,,"is an assay which uses initial modification of DNA by sodium bisulfite, converting all unmethylated, but not methylated, cytosines to uracil, and subsequent amplification with primers specific for methylated versus unmethylated DNA.",PMID:8790415,,,,,"2015-03-30 OBI dev call:
The assay was defined as equvivalent to
(assay and (has_specified_input some 'binding complex 3D structure determination assay') and (has_specified_output some 
('data item' and ('is about' some 'regulation of DNA methylation')))) and (achieves_planned_objective some 'epigenetic modification identification objective')
 'binding complex 3D structure determination assay' is a process and cannot be the input of another process which cause inconsistent.
In the call, we decided to remove axiom and will discuss it in the assay harmonization discussion.
see tracker:
https://sourceforge.net/p/obi/obi-terms/747/

",methylation-specific polymerase chain reaction ,,Methylation status of breast cancer resistance protein detected by methylation-specific polymerase chain reaction analysis is correlated inversely with its expression in drug-resistant lung cancer cells. PMID: 18219662,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001684,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,methylation-specific polymerase chain reaction ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra; Marcus Chibucos,,
http://purl.obolibrary.org/obo/GO_0019904,protein domain specific binding,,Interacting selectively and non-covalently with a specific domain of a protein.,false,,,http://purl.obolibrary.org/obo/OBI_0001588,,,,,,,,,,,,,,,,,,,Interacting selectively and non-covalently with a specific domain of a protein.,,,,,,,protein domain specific binding,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0019904,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,protein domain specific binding,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001020,Lead structure mapping assay,single nucleotide resolution mapping assay using Lead probe,a single-nucleotide-resolution nucleic acid structure mapping assay which uses lead as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,false,,,http://purl.obolibrary.org/obo/OBI_0001017,,http://purl.obolibrary.org/obo/OBI_0000441,,single nucleotide resolution mapping assay using Lead probe,,,,,,,,,,,,,,,a single-nucleotide-resolution nucleic acid structure mapping assay which uses lead as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,RNA ontology,,,,,,Lead structure mapping assay,,PMID:2686708,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001020,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Lead structure mapping assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001864,RNA Annotation and Mapping of Promoters for the Analysis of Gene Expression assay,RAMPAGE,"An assay that identifies transcription start sites (TSS), the quantification of their expression and the characterization
of their transcripts using high throughput sequencing.",false,,,http://purl.obolibrary.org/obo/OBI_0600047|http://purl.obolibrary.org/obo/OBI_0000424,,http://purl.obolibrary.org/obo/OBI_0001851,,RAMPAGE,,,,,,,,,,,,,,,"An assay that identifies transcription start sites (TSS), the quantification of their expression and the characterization
of their transcripts using high throughput sequencing.",Batut et al. High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression. Genome Research. 2013 Jan;23(1):169-80. [PMID:22936248],,,,,,RNA Annotation and Mapping of Promoters for the Analysis of Gene Expression assay,,Batut et al. High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression. Genome Research. 2013 Jan;23(1):169-80. [PMID:22936248],,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0600023|http://purl.obolibrary.org/obo/OBI_0001177|http://purl.obolibrary.org/obo/OBI_0000711,http://purl.obolibrary.org/obo/OBI_0400103,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001573,,,OBI:0001864,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,RNA Annotation and Mapping of Promoters for the Analysis of Gene Expression assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0400098,SomaScope,,The SomaScope is an instrument to quantify somatic cells in milk.,false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,,,,,,,,,,,,,,,,The SomaScope is an instrument to quantify somatic cells in milk.,"""http://www.aicompanies.com/DeltaCD/soma_auto_adv.htm, 2007-05-10""",,,,,,SomaScope,,SomaScope Mark II Automatic Economical,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400098,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,SomaScope,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Josef Spidlen,,
http://purl.obolibrary.org/obo/OBI_0001623,organism identification objective,,A biological feature identification objective to identify the organism species in a specimen.,false,,,http://purl.obolibrary.org/obo/OBI_0000015,,,,,,,,,,,,,,,,,,,A biological feature identification objective to identify the organism species in a specimen.,Penn Group,,,,,,organism identification objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001623,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,organism identification objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001757,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells,CXCL9/MIG release|RNA/DNA detection,An assay of epitope specific chemokine (C-X-C motif) ligand 9 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001459,,,,,,,,,,,,,,,,,,,An assay of epitope specific chemokine (C-X-C motif) ligand 9 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001757,,,,,,,,,,,,,,,,,,,,,,,,CXCL9/MIG release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0002045,poly(A)-site sequencing assay,PAS-seq assay|Poly(A)-site sequencing|PAS-seq,A RNA-seq assay for quantitatively profiling RNA polyadenylation at the transcriptome level.,false,,,http://purl.obolibrary.org/obo/OBI_0001271,,,,PAS-seq assay|Poly(A)-site sequencing|PAS-seq,,,,,,,,,,,,,,,A RNA-seq assay for quantitatively profiling RNA polyadenylation at the transcriptome level.,"Shepard et al., (April 2011). ""Complex and dynamic landscape of RNA polyadenylation revealed by PAS-Seq."" RNA. 2011 Apr;17(4):761-72. doi: 10.1261/rna.2581711",,,,,,poly(A)-site sequencing assay,,"Wu et al., (July 2014). ""Genome-wide determination of poly(A) sites in Medicago truncatula: evolutionary conservation of alternative poly(A) site choice. BMC Genomics. 2014 Jul 21;15:615. doi: 10.1186/1471-2164-15-615.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002045,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,poly(A)-site sequencing assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/CHEBI_37586,sodium phosphate,,,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,,,,,,,,sodium phosphate,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:37586,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,sodium phosphate,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000732,restriction enzyme,,an enzyme that has a specific target cleavage sites within nucleic acids,false,,,http://purl.obolibrary.org/obo/PR_000000001|http://purl.obolibrary.org/obo/OBI_0000427,,,,,,,,,,,,,,,,,5/22 Need to explore if there are GO / other classes exist that capture this. We need it now for cloning experiments,,an enzyme that has a specific target cleavage sites within nucleic acids,,,,,,,restriction enzyme,,The enzyme EcoR1 cuts DNA at the canonical cleavage site CAATTG,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/GO_0003824,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000732,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,restriction enzyme,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Kevin Clancy, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001208,epitope specific T cell activation,,A process of T cell activation resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0042110,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of T cell activation resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific T cell activation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001208,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific T cell activation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001136,surface plasmon resonance instrument,,A tool for measuring adsorption of material onto planar metal (typically gold and silver) surfaces or onto the surface of metal nanoparticles.,false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,A tool for measuring adsorption of material onto planar metal (typically gold and silver) surfaces or onto the surface of metal nanoparticles.,http://en.wikipedia.org/wiki/Surface_plasmon_resonance,,,,,,surface plasmon resonance instrument,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001136,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,surface plasmon resonance instrument,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001824,intracellular cytokine staining assay measuring epitope specific interleukin-18 production by T cells,IL-18 release|ICS,An assay of epitope specific interleukin-18 production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001380,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-18 production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-18 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001824,,,,,,,,,,,,,,,,,,,,,,,,IL-18 release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-18 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001009,obsolete_qualitative binding detection assay,,"A binding assay where the specified output determines if two or more material entities do or do not have the disposition to form a complex above a threshold level of significance. The threshold can be defined through detection limits of the instrument, the use of experimental controls that establish what is considered significant binding, or a predefined cutoff based on what binding is considered significant in a certain context. ",true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,"A binding assay where the specified output determines if two or more material entities do or do not have the disposition to form a complex above a threshold level of significance. The threshold can be defined through detection limits of the instrument, the use of experimental controls that establish what is considered significant binding, or a predefined cutoff based on what binding is considered significant in a certain context. ",,,,,,,obsolete_qualitative binding detection assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,OBI:0001009,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_qualitative binding detection assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Bjoern Peters, Randi Vita, Jason Greenbaum",,
http://purl.obolibrary.org/obo/OBI_0000650,differential expression analysis data transformation,,A differential expression analysis data transformation is a data transformation that has objective differential expression analysis and that consists of,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,A differential expression analysis data transformation is a data transformation that has objective differential expression analysis and that consists of,WEB:,,,,,,differential expression analysis data transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000650,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,differential expression analysis data transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Monnie McGee|Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0001306,RNA stability design,,A study design that examines the stability and/or decay of RNA transcripts.,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,A study design that examines the stability and/or decay of RNA transcripts.,MO_553 RNA_stability_design,,,,,,RNA stability design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001306,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,RNA stability design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001348,in vivo skin test assay measuring T cell epitope specific type IV hypersensitivity,type IV hypersensitivity (DTH)|in vivo skin test,An efficacy of T cell epitope intervention experiment that detects epitope specific type IV hypersensitivity.,false,,,http://purl.obolibrary.org/obo/OBI_0001484,,,,,,,,,,,,,,,,,,,An efficacy of T cell epitope intervention experiment that detects epitope specific type IV hypersensitivity.,IEDB,,,,,,in vivo skin test assay measuring T cell epitope specific type IV hypersensitivity,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001348,,,,,,,,,,,,,,,,,,,,,,,,type IV hypersensitivity (DTH)|in vivo skin test,,,,,,,,,,,,,,,,,,,,,,in vivo skin test assay measuring T cell epitope specific type IV hypersensitivity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001918,RNA-binding protein immunoprecipitation array profiling assay,RIP-chip assay|RIP-chip,An assay that combines immunoprecipitation of an RNA-binding protein and array technology to identify mRNAs associated with selected RNA binding proteins (RBPs).,false,,,http://purl.obolibrary.org/obo/OBI_0000443,,http://purl.obolibrary.org/obo/OBI_0000437|http://purl.obolibrary.org/obo/OBI_0001854,,RIP-chip assay|RIP-chip,,,,,,,,,,,,,,,An assay that combines immunoprecipitation of an RNA-binding protein and array technology to identify mRNAs associated with selected RNA binding proteins (RBPs).,Jain et al. RIP-Chip analysis: RNA-Binding Protein Immunoprecipitation-Microarray (Chip) Profiling. Methods Mol Biol. 2011;703:247-63. [PMID:21125495],,,,,,RNA-binding protein immunoprecipitation array profiling assay,,Jain et al. RIP-Chip analysis: RNA-Binding Protein Immunoprecipitation-Microarray (Chip) Profiling. Methods Mol Biol. 2011;703:247-63. [PMID:21125495],,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000690|http://purl.obolibrary.org/obo/OBI_0000711,http://purl.obolibrary.org/obo/OBI_0400148,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000109,,,OBI:0001918,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,RNA-binding protein immunoprecipitation array profiling assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000175,p-value,,"A quantitative confidence value that represents the probability of obtaining a result at least as extreme as that actually obtained, assuming that the actual value was the result of chance alone.",false,,,http://purl.obolibrary.org/obo/OBI_0000071,,,,,,,,,,,,,,,,,,,"A quantitative confidence value that represents the probability of obtaining a result at least as extreme as that actually obtained, assuming that the actual value was the result of chance alone.",WEB: http://en.wikipedia.org/wiki/P-value,,,,,"May be outside the scope of OBI long term, is needed so is retained",p-value,,"PMID:19696660
in contrast to the in-vivo data AT-III increased significantly from
113.5% at baseline to 117% after 4 days (n = 10, P-value= 0.02; Table 2).",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000121,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000175,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,p-value,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Chris Stoeckert,,
http://purl.obolibrary.org/obo/ENVO_00010483,environmental material,,A portion of environmental material is a fiat object which forms the medium or part of the medium of an environmental system.,false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,A portion of environmental material is a fiat object which forms the medium or part of the medium of an environmental system.,,,,,,,environmental material,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENVO:00010483,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/envo.owl,,,,,,,,,,,,,,,,,,,environmental material,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001594,cell bound MHC competitive binding assay of a MHC:ligand complex using fluorescence detection,qualitative binding|cellular MHC/competitive/fluorescence,A cell bound MHC binding assay that uses fluorescence to detect loss of binding of a known reference ligand due to competition by the ligand under investigation,false,,,http://purl.obolibrary.org/obo/OBI_0001550|http://purl.obolibrary.org/obo/OBI_0001499,,,,,,,,,,,,,,,,,,,A cell bound MHC binding assay that uses fluorescence to detect loss of binding of a known reference ligand due to competition by the ligand under investigation,IEDB,,,,,,cell bound MHC competitive binding assay of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001501,,,,,,,,,,,,,,,,OBI:0001594,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|cellular MHC/competitive/fluorescence,,,,,,,,,,,,,,,,,,,,,,cell bound MHC competitive binding assay of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/GO_0006974,cellular response to DNA damage stimulus,,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.",false,,,http://purl.obolibrary.org/obo/GO_0050896,,,,,,,,,,,,,,,,,,,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.",,,,,,,cellular response to DNA damage stimulus,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0006974,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,cellular response to DNA damage stimulus,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200191,gene list visualization,,Adata visualization which has input of a gene list and produces an output of a report graph which is capable of rendering data of this type.,false,,,http://purl.obolibrary.org/obo/OBI_0200111,,,,,,,,,,,,,,,,,,,Adata visualization which has input of a gene list and produces an output of a report graph which is capable of rendering data of this type.,,,,,,,gene list visualization,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000306,,,OBI:0200191,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,gene list visualization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0600036,establishing cell culture,,"a process through which a new type of cell culture or cell line is created, either through the isolation and culture of one or more cells from a fresh source, or the deliberate experimental modification of an existing cell culture (e.g passaging a primary culture to become a secondary culture or line, or the immortalization or stable genetic modification of an existing culture or line).|A 'cell culture' as used here referes to a new lineage of cells in culture deriving from a single biological source.. New cultures are established through the initial isolation and culturing of cells from an organismal source, or through changes in an existing cell culture or line that result in a new culture with unique characteristics.  This can occur through the passaging/selection of a primary culture into a secondary culture or line, or experimental modifications of an existing cell culture or line such as an immortalization process or other stable genetic modification. This class covers establishment of cultures of either multicellular organism cells or unicellular organisms.",false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,"a process through which a new type of cell culture or cell line is created, either through the isolation and culture of one or more cells from a fresh source, or the deliberate experimental modification of an existing cell culture (e.g passaging a primary culture to become a secondary culture or line, or the immortalization or stable genetic modification of an existing culture or line).",PERSON:Matthew Brush,,,,,,establishing cell culture,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CL_0000000|http://purl.obolibrary.org/obo/OBI_0000079,http://purl.obolibrary.org/obo/OBI_0100060,,,OBI:0600036,,,,,,,,,,,,,,,,,,"A 'cell culture' as used here referes to a new lineage of cells in culture deriving from a single biological source.. New cultures are established through the initial isolation and culturing of cells from an organismal source, or through changes in an existing cell culture or line that result in a new culture with unique characteristics.  This can occur through the passaging/selection of a primary culture into a secondary culture or line, or experimental modifications of an existing cell culture or line such as an immortalization process or other stable genetic modification. This class covers establishment of cultures of either multicellular organism cells or unicellular organisms.",,,,,,,,,,,,,,,,,,,,,,,,,,,,establishing cell culture,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_0000631,Varian MERCURY spectrometer,,"MERCURYplus spectrometers provide superior control, stability, and performance for high-productivity environments. Surface-mount electronics enable a small footprint without compromising data quality. Modular design allows flexible configuration. Direct digital synthesis, linear amplifiers, and other innovative RF and digital technologies enable push-button operation.",false,,,http://purl.obolibrary.org/obo/OBI_0000611,,,,,,,,,,,,,,,,,NMR instrument,,"MERCURYplus spectrometers provide superior control, stability, and performance for high-productivity environments. Surface-mount electronics enable a small footprint without compromising data quality. Modular design allows flexible configuration. Direct digital synthesis, linear amplifiers, and other innovative RF and digital technologies enable push-button operation.",WEB:<http://www.varianinc.com/cgi-bin/nav?varinc/docs/products/NMR/spectromet/mercury/index&cid=975JINLIKLRMPGLMNOILJ>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400235,,,,,,Varian MERCURY spectrometer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000631,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Varian MERCURY spectrometer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0400054,Amnis ImageStream,,"The ImageStream is a multispectral_imaging_flow_cytometer manufactured by Amnis. Its has digital electronics, a single standard 488 nm solid state laser. In addition an optional 658 nm and your choice of either a 405 nm or 375 nm solid state laser can be added. Information is collected using cameras. The ImageStream system CCD camera produces six images of each cell, including darkfield, brightfield, and up to four fluorescent colors. Each image is used to calculate over 40 features, so a six-image assay results in ~250 morphometric and photometric features per cell. The ImageStream is a flow cytometer that takes pictures of the cells in flow.
It has both components, an Image cytometer and a flow cytometer.",false,,,http://purl.obolibrary.org/obo/OBI_0400146,,,,,,,,,,,,,,,,,,,"The ImageStream is a multispectral_imaging_flow_cytometer manufactured by Amnis. Its has digital electronics, a single standard 488 nm solid state laser. In addition an optional 658 nm and your choice of either a 405 nm or 375 nm solid state laser can be added. Information is collected using cameras. The ImageStream system CCD camera produces six images of each cell, including darkfield, brightfield, and up to four fluorescent colors. Each image is used to calculate over 40 features, so a six-image assay results in ~250 morphometric and photometric features per cell. The ImageStream is a flow cytometer that takes pictures of the cells in flow.
It has both components, an Image cytometer and a flow cytometer.",http://www.amnis.com/,,,,,"It has both components, an Image cytometer and a flow cytometer.",Amnis ImageStream,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0400044|http://purl.obolibrary.org/obo/OBI_0400135,,,,,,,,,,,,,,,,OBI:0400054,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Amnis ImageStream,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Melanie Courtot|John Quinn,,
http://purl.obolibrary.org/obo/BFO_0000003,occurrent,,"An entity that has temporal parts and that happens, unfolds or develops through time.",false,,,http://purl.obolibrary.org/obo/BFO_0000001,,,,,,,Occurrent,occurrent,,,,,,,,,,,"An entity that has temporal parts and that happens, unfolds or develops through time.",,,,,,"Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame.|Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process.|BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region|BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players.",occurrent,An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002]),,,,,,,,,(forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] |(forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] ,Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])|b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001]),,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000003,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,occurrent,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200137,network subgraph quality calculation,,A network analysis in which an input data set describing node objects and edge relationships between node objects is used to determine the output quality of a subgraph partition of the network.,false,,,http://purl.obolibrary.org/obo/OBI_0200080,,,,,,,,,,,,,,,,,,,A network analysis in which an input data set describing node objects and edge relationships between node objects is used to determine the output quality of a subgraph partition of the network.,PERSON: Richard Scheuermann,,,,,,network subgraph quality calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200137,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,network subgraph quality calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Richard Scheuermann,,
http://purl.obolibrary.org/obo/OBI_0001492,in vivo assay measuring T cell epitope specific protection based on survival,survival from challenge|in vivo assay,A T cell epitope in vivo intervention experiment that uses a protection from challenge in vivo intervention experiment based on survival.,false,,,http://purl.obolibrary.org/obo/OBI_0002073,,,,,,,,,,,,,,,,,,,A T cell epitope in vivo intervention experiment that uses a protection from challenge in vivo intervention experiment based on survival.,IEDB,,,,,,in vivo assay measuring T cell epitope specific protection based on survival,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001492,,,,,,,,,,,,,,,,,,,,,,,,survival from challenge|in vivo assay,,,,,,,,,,,,,,,,,,,,,,in vivo assay measuring T cell epitope specific protection based on survival,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000851,obsolete_diethyl pyrocarbonate,,Replaced by CHEBI_59051 Diethylpyrocarbonate,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_diethyl pyrocarbonate,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000228,,,,,,,,,,,,,,,,,,OBI:0000851,,,,,,,,,,,,,,,,,,Replaced by CHEBI_59051 Diethylpyrocarbonate,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_diethyl pyrocarbonate,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/BFO_0000004,independent continuant,,"b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])|A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.",false,,,http://purl.obolibrary.org/obo/BFO_0000002,,,,,,,IndependentContinuant,ic,,,,,,,,,,,"b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])|A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.",,,,,,,independent continuant,,a leg|an orchestra.|a molecule|an organism|the bottom right portion of a human torso|the interior of your mouth|an atom|a chair|a spatial region|a heart,,,,,,,,(iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] |(forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] |(forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] ,"For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])|For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000004,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,independent continuant,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001681,yeast one-hybrid ,Y1H,The one-hybrid variation of this technique is designed to investigate protein–DNA interactions and uses a single fusion protein in which the AD is linked directly to the binding domain. ,false,,,http://purl.obolibrary.org/obo/OBI_0000070|http://purl.obolibrary.org/obo/OBI_0001146,,,,Y1H,,,,,,,,,,,,,add regulatory region DNA binding;obo:GO:0000975;,,The one-hybrid variation of this technique is designed to investigate protein–DNA interactions and uses a single fusion protein in which the AD is linked directly to the binding domain. ,PMID: 22218861,,,,,,yeast one-hybrid ,,"Yeast one-hybrid assays for gene-centered human gene regulatory network mapping. Nat Methods. 2011 Oct 30;8(12):1050-2. doi: 10.1038/nmeth.1764.
PMID: 22037702 ",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001681,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,yeast one-hybrid ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra; Marcus Chibucos,,
http://purl.obolibrary.org/obo/ENVO_00002257,podzol,,"Podzols are soils with a typically ash-grey upper subsurface horizon, bleached by loss of organic matter and iron oxides, on top of a dark accumulation horizon with brown, reddish or black illuviated humus and/or reddish Fe compounds. Podzols occur in humid areas in the boreal and temperate zones and locally also in the tropics.",false,,,http://purl.obolibrary.org/obo/ENVO_00001998,,,,,,,,,,,,,,,,,,,"Podzols are soils with a typically ash-grey upper subsurface horizon, bleached by loss of organic matter and iron oxides, on top of a dark accumulation horizon with brown, reddish or black illuviated humus and/or reddish Fe compounds. Podzols occur in humid areas in the boreal and temperate zones and locally also in the tropics.",,,,,,,podzol,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENVO:00002257,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/envo.owl,,,,,,,,,,,,,,,,,,,podzol,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001837,ELISA measuring epitope specific interleukin-16 production by T cells,IL-16 release|ELISA,An assay of epitope specific interleukin-16 production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001280,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-16 production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific interleukin-16 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001837,,,,,,,,,,,,,,,,,,,,,,,,IL-16 release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific interleukin-16 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000097,participant under investigation role,,A role that is realized through the execution of a study design in which the bearer of the role participates and in which data about that bearer is collected.,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,"Following OBI call November 2012,26th:
 
1. it was decided there was no need for moving the children class and making them siblings of study subject role.
2. it also settles the disambiguation about 'study subject'. This is about the individual participating in the investigation/study, Not the 'topic' (as in 'toxicity study') of the investigation/study

This note closes the issue and validates the class definition to be part of the OBI core
editor = PRS
",,A role that is realized through the execution of a study design in which the bearer of the role participates and in which data about that bearer is collected.,OBI,,,,,"A participant can realize both ""specimen role"" and ""participant under investigation role"" at the same time. However ""participant under investigation role"" is distinct from ""specimen role"", since a specimen could somehow be involved in an investigation without being the thing that is under investigation.",participant under investigation role,,"Human subjects in a clinical trial, rats in a toxicogenomics study, tissue cutlures subjected to drug tests, fish observed in an ecotoxicology study. 
Parasite example: people are infected with a parasite which is then extracted; the particpant under investigation could be the parasite, the people, or a population of which the people are members, depending on the nature of the study.
Lake example: a lake could realize this role in an investigation that assays pollution levels in samples of water taken from the lake.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000097,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,participant under investigation role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP:  Role Branch,,
http://purl.obolibrary.org/obo/OBI_0001876,cell culture,,"A material entity comprised of cultured cells and the media in which they are being propagated or stored.|A cell culture includes the cells in culture, as well as the media and all additives in which the cells are being grown or in which they are stored.",false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,,,,,,,,,,,,,,,,A material entity comprised of cultured cells and the media in which they are being propagated or stored.,OBI-CLO Alignment Working Group (Spring 2013),,,,,,cell culture,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CL_0000010,,,,,,,,,,,,,,,,OBI:0001876,,,,,,,,,,,,,,,,,,"A cell culture includes the cells in culture, as well as the media and all additives in which the cells are being grown or in which they are stored.",,,,,,,,,,,,,,,,,,,,,,,,,,,,cell culture,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_0000406,PCR product,,is double stranded DNA that is the specified output of a polymerase chain reaction,false,,,http://purl.obolibrary.org/obo/OBI_0000809|http://purl.obolibrary.org/obo/CHEBI_4705,,,,,,,,,,,,,,,,,,,is double stranded DNA that is the specified output of a polymerase chain reaction,GROUP: OBI BIomaterial Branch,,,,,"We are using PCR and not the written out words, as this is the most common used.",PCR product,,PCR products are the results of amplifcation process. Detection of a PCR products is used to detect DNA and RNA.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000406,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PCR product,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP: OBI BIomaterial Branch,,
http://purl.obolibrary.org/obo/OBI_0001887,email address of Bioinformatics Resource Center contact person,Bioinformatics Resource Center Contact's email,An email address of the person who is contact representative of a Bioinformatics Resource Center,false,,,http://purl.obolibrary.org/obo/IAO_0000429,,,,,,,,,,,,,,,,,,,An email address of the person who is contact representative of a Bioinformatics Resource Center,NIAID GSCID-BRC metadata working group,,,,,,email address of Bioinformatics Resource Center contact person,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001887,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,email address of Bioinformatics Resource Center contact person,,,,,,Bioinformatics Resource Center Contact's email,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001267,epitope specific transforming growth factor-beta production by T cells,,A process of transforming growth factor-beta production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0071604|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of transforming growth factor-beta production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific transforming growth factor-beta production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001267,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific transforming growth factor-beta production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001161,age since germination measurement datum,,"An age measurement datum that is the result of the measurement of the age of an organism since germination, the process consisting of physiological and developmental changes by a seed, spore, pollen grain (microspore), or zygote that occur after release from dormancy, and encompassing events prior to and including the first visible indications of growth.",false,,,http://purl.obolibrary.org/obo/OBI_0001167,,,,,,,,,,,,,,,,,,,"An age measurement datum that is the result of the measurement of the age of an organism since germination, the process consisting of physiological and developmental changes by a seed, spore, pollen grain (microspore), or zygote that occur after release from dormancy, and encompassing events prior to and including the first visible indications of growth.",MO_590 germination,,,,,"Definition of germination comes from GO. However, the term is deprecated from GO now because it is a grouping term without biological significance.",age since germination measurement datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001161,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,age since germination measurement datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/IAO_0000005,objective specification,goal specification,a directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved.,false,,,http://purl.obolibrary.org/obo/IAO_0000033,,,,goal specification,,,,,,,,,,,,,,,a directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved.,OBI_0000217|OBI Plan and Planned Process/Roles Branch,,,,,"2009-03-16: original definition when imported from OBI read: ""objective is an non realizable information entity which can serve as that  proper part of a plan towards which the realization of the plan is directed.""|Answers the question, why did you do this experiment?|2014-03-31: In the example of usage (""In the protocol of a ChIP assay the objective specification says to identify protein and DNA interaction"") there is a protocol which is the ChIP assay protocol. In addition to being concretized on paper, the protocol can be concretized as a realizable entity, such as a plan that inheres in a person. The objective specification is the part that says that some protein and DNA interactions are identified. This is a specification of a process endpoint: the boundary in the process before which they are not identified and after which they are. During the realization of the plan, the goal is to get to the point of having the interactions, and participants in the realization of the plan try to do that.",objective specification,,In the protocol of a ChIP assay the objective specification says to identify protein and DNA interaction.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000005,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,objective specification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters|PERSON: Jennifer Fostel|PERSON: Alan Ruttenberg|PERSON: Barry Smith,,
http://purl.obolibrary.org/obo/OBI_0001780,ELISPOT assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells,CCL3/MIP-1a release|ELISPOT,An assay of epitope specific macrophage inflammatory protein-1 alpha production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001333,,,,,,,,,,,,,,,,,,,An assay of epitope specific macrophage inflammatory protein-1 alpha production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001780,,,,,,,,,,,,,,,,,,,,,,,,CCL3/MIP-1a release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/CLO_0000001,cell line cell,,A cultured cell that is part of a cell line - a stable and homogeneous population of cells with a common biological origin and propagation history in culture,false,,,http://purl.obolibrary.org/obo/OBI_0001866,,,,,,,,,,,,,,,,,,,A cultured cell that is part of a cell line - a stable and homogeneous population of cells with a common biological origin and propagation history in culture,,,http://purl.obolibrary.org/obo/CL_0000001,,,,cell line cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CLO:0000001,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/clo.owl,,,,,,,,,,,,,,,,,,,cell line cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001865,assay array,,A device made to be used in an analyte assay for immobilization of substances that bind the analyte at regular spatial positions on a surface.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A device made to be used in an analyte assay for immobilization of substances that bind the analyte at regular spatial positions on a surface.,Penn Group,,,,,,assay array,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000399,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001865,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,assay array,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng, Alan Ruttenberg",,
http://purl.obolibrary.org/obo/OBI_1110178,intracellular cytokine staining assay measuring epitope specific interleukin-17 production by T cells,IL-17 release|ICS,An assay of epitope specific interleukin-17 production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001295,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-17 production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-17 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110178,,,,,,,,,,,,,,,,,,,,,,,,IL-17 release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-17 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001587,biological activity assay measuring epitope specific interleukin-7 production by T cells,IL-7 release|biological activity,A T cell epitope specific cytokine production assay that detects interleukin-7 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects interleukin-7 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific interleukin-7 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001587,,,,,,,,,,,,,,,,,,,,,,,,IL-7 release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific interleukin-7 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000860,northern blot analysis,northern blot,"a northern blot analysis is an assay allowing monitoring presence of gene transcripts  by hybridizing labeled RNA or DNA probes against messenger RNAs isolated from tissue or cell cultures, resolved on denaturing agarose gel, transfered by blotting procedure to a nitrocellulose or nylon membrane and immobilized by cross linking or baking to the membrane. Detection of  hybridization signals is carried out by immunofluorescence or radioactivity measurements using photographic films or digital imaging devices such as Phosphor Imager",false,,,http://purl.obolibrary.org/obo/OBI_0000443,,http://purl.obolibrary.org/obo/OBI_0000441,,northern blot,,,,,,,,,,,,,,,"a northern blot analysis is an assay allowing monitoring presence of gene transcripts  by hybridizing labeled RNA or DNA probes against messenger RNAs isolated from tissue or cell cultures, resolved on denaturing agarose gel, transfered by blotting procedure to a nitrocellulose or nylon membrane and immobilized by cross linking or baking to the membrane. Detection of  hybridization signals is carried out by immunofluorescence or radioactivity measurements using photographic films or digital imaging devices such as Phosphor Imager",,,,,,2010-01-31: Philippe Rocca-Serra: Need to add a restriction taking into account probe and transcript information,northern blot analysis,,"PMID: 18428227. Analysis of RNA by northern blot hybridization.
Brown T, Mackey K.  Curr Protoc Hum Genet. 2001 Nov;Appendix 3:Appendix 3K.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000860,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,northern blot analysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/IAO_0000313,patent,,A document that has been accepted by a patent authority,false,,,http://purl.obolibrary.org/obo/IAO_0000310,,,,,,,,,,,,,,,,,,,A document that has been accepted by a patent authority,,,,,,,patent,,"US Patent 6,449,603",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000313,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,patent,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/UO_0000270,volumetric flow rate unit,,A unit which is a standard measure of the volume of fluid which passes through a given surface per unit time .,false,,,http://purl.obolibrary.org/obo/IAO_0000003,,,,,,,,,,,,,,,,,,,A unit which is a standard measure of the volume of fluid which passes through a given surface per unit time .,,,,,,,volumetric flow rate unit,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UO:0000270,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uo.owl,,,,,,,,,,,,,,,,,,,volumetric flow rate unit,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001097,liquid extraction robot,,A liquid handling device that provides automatic liquid extraction.,false,,,http://purl.obolibrary.org/obo/OBI_0400112,,,,,,,,,,,,,,,,,,,A liquid handling device that provides automatic liquid extraction.,PERSON: Erik Segerdell,,,,,,liquid extraction robot,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000379,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001097,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,liquid extraction robot,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001581,equilibrium dissociation constant (KD) approximated by EC50,,"A measurement of an EC50 value under specific assay conditions approximates KD, namely the binding reaction is at an equilibrium,  and the concentration of the receptor must be much less than the KD for the ligand.  ",false,,,http://purl.obolibrary.org/obo/OBI_0001180|http://purl.obolibrary.org/obo/OBI_0001144,,,,,,,,,,,,,,,,,,,"A measurement of an EC50 value under specific assay conditions approximates KD, namely the binding reaction is at an equilibrium,  and the concentration of the receptor must be much less than the KD for the ligand.  ","Assay Development: Fundamentals and Practices, By Ge Wu, page 74",,,,,,equilibrium dissociation constant (KD) approximated by EC50,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001581,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,equilibrium dissociation constant (KD) approximated by EC50,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Bjoern Peters, Randi Vita",,
http://purl.obolibrary.org/obo/OBI_0001552,intracellular cytokine staining assay measuring epitope specific tumor necrosis factor (ligand) superfamily member 11 production by T cells,TNFSF11/RANKL release|ICS,A T cell epitope specific tumor necrosis factor (ligand) superfamily member 11 production assay that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001385|http://purl.obolibrary.org/obo/OBI_0001607,,,,,,,,,,,,,,,,,,,A T cell epitope specific tumor necrosis factor (ligand) superfamily member 11 production assay that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific tumor necrosis factor (ligand) superfamily member 11 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001552,,,,,,,,,,,,,,,,,,,,,,,,TNFSF11/RANKL release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific tumor necrosis factor (ligand) superfamily member 11 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001059,ELISA microplate reader,,A microplate reader that is used for enzyme-linked immunosorbent assays (ELISA).,false,,,http://purl.obolibrary.org/obo/OBI_0001058,,,,,,,,,,,,,,,,,,,A microplate reader that is used for enzyme-linked immunosorbent assays (ELISA).,PERSON: Erik Segerdell,,,,,,ELISA microplate reader,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001059,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ELISA microplate reader,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0200124,kurtosis calculation,,"A kurtosis calculation is a descriptive statistics calculation defined as a parameter that measures how large or small the tails of a distribution are relative to the mean.  For details, see http://davidmlane.com/hyperstat/A53638.html",false,,,http://purl.obolibrary.org/obo/OBI_0200184|http://purl.obolibrary.org/obo/OBI_0200086,,http://purl.obolibrary.org/obo/OBI_0200078|http://purl.obolibrary.org/obo/OBI_0200180,,,,,,,,,,,,,,,From Monnie's file comments - need to add moment calculation role but they doesn't exist yet - (editor note added by James Jan 2008),,"A kurtosis calculation is a descriptive statistics calculation defined as a parameter that measures how large or small the tails of a distribution are relative to the mean.  For details, see http://davidmlane.com/hyperstat/A53638.html",WEB: http://davidmlane.com/hyperstat/A53638.html,,,,,,kurtosis calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200124,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,kurtosis calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Monnie McGee,,
http://purl.obolibrary.org/obo/OBI_0000038,chromatography column,,Chromatography column in chemistry is a tube and contents (typically glass) used to purify individual chemical compounds from mixtures of compounds. It is often used for preparative applications on scales from micrograms up to kilograms.,false,,,http://purl.obolibrary.org/obo/OBI_0000932,,,,,,,,,,,,,,,,,open tracker https://sourceforge.net/tracker/index.php?func=detail&aid=2881353&group_id=177891&atid=886178,,Chromatography column in chemistry is a tube and contents (typically glass) used to purify individual chemical compounds from mixtures of compounds. It is often used for preparative applications on scales from micrograms up to kilograms.,http://en.wikipedia.org/wiki/Column_chromatography,,,,,,chromatography column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000967,,,,,,,,,,,,,,,,OBI:0000038,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,chromatography column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Frank Gibson,,
http://purl.obolibrary.org/obo/OBI_0200092,Westfall and Young family wise error rate correction,Westfall and Young FWER correction,Is a data transformation process in which the Westfall and Young method is applied with the aim of controlling for multiple testing,false,,,http://purl.obolibrary.org/obo/OBI_0200073,,http://purl.obolibrary.org/obo/OBI_0000791,,Westfall and Young FWER correction,,,,,,,,,,,,,,,Is a data transformation process in which the Westfall and Young method is applied with the aim of controlling for multiple testing,,,,,,"PRS: 2011-03-31: set specified input and specified output to the data transformation|2011-03-31: [PRS]. 
specified input and output of dt which were missing",Westfall and Young family wise error rate correction,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000175,http://purl.obolibrary.org/obo/OBI_0001265,,,OBI:0200092,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Westfall and Young family wise error rate correction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0001307,tiling microarray,genome tiling array,a DNA microarray which has short fragments of nucleic acid immobilized on a substrate. These are designed to cover the whole genome of the target species. Tiling arrays are used to determine genome binding in ChIP assays or to identify transcribed regions.,false,,,http://purl.obolibrary.org/obo/OBI_0400148,,,,genome tiling array,,,,,,,,,,,,,,,a DNA microarray which has short fragments of nucleic acid immobilized on a substrate. These are designed to cover the whole genome of the target species. Tiling arrays are used to determine genome binding in ChIP assays or to identify transcribed regions.,EFO_0002704: tiling array,,,,,,tiling microarray,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001307,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,tiling microarray,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0400030,dichroic filter,,A dichroic filter is an optical filter which is used to selectively pass light of a small range of colors while reflecting other colors. A dichroic filter passes the specified range of light whereas a dichroic mirror reflects the specified range of light.,false,,,http://purl.obolibrary.org/obo/OBI_0400079,,,,,,,,,,,,,,,,,,,A dichroic filter is an optical filter which is used to selectively pass light of a small range of colors while reflecting other colors. A dichroic filter passes the specified range of light whereas a dichroic mirror reflects the specified range of light.,http://en.wikipedia.org/wiki/Dichroic_filter,,,,,,dichroic filter,,Cy3 Dichroic Filter,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400030,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,dichroic filter,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0000510,reversed phase column,,A reversed phase column is a chromatography column in which the mobile phase is more polar than the stationary phase. Its counterpart is the normal phase column.,false,,,http://purl.obolibrary.org/obo/OBI_0000038,,,,,,,,,,,,,,,,,,,A reversed phase column is a chromatography column in which the mobile phase is more polar than the stationary phase. Its counterpart is the normal phase column.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01106,,,,,,reversed phase column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000510,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,reversed phase column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000065,"polyethylene glycol p-(1,1,3,3-tetramethylbutyl)-phenyl ether",,triton X100 is a chemical entity which belongs to the group of The pluronics which are triblock copolymers of ethylene oxide and propylene oxide. Triton x-100 is_used_as detergent due to its non-ionic surfactant properties,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,triton X100 is a chemical entity which belongs to the group of The pluronics which are triblock copolymers of ethylene oxide and propylene oxide. Triton x-100 is_used_as detergent due to its non-ionic surfactant properties,adapted from Wikipedia before possible import from CHEBI,,,,,,"polyethylene glycol p-(1,1,3,3-tetramethylbutyl)-phenyl ether",,PMID: 30799. J Histochem Cytochem. 1978 Sep;26(9):696-712. Acid lipase: a histochemical and biochemical study using triton X100-naphtyl palmitate micelles.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000065,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"polyethylene glycol p-(1,1,3,3-tetramethylbutyl)-phenyl ether",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/IAO_0000305,document title,,A textual entity that names a document,false,,,http://purl.obolibrary.org/obo/IAO_0000300,,,,,,,,,,,,,,,,,,,A textual entity that names a document,,,,,,,document title,,Textual characteristics of traditional and Open Access scientific journals are similar,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000305,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,document title,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0000323,obsolete_peritoneum,,is the serous membrane that forms the lining of the abdominal cavity,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,is the serous membrane that forms the lining of the abdominal cavity,,,,,,"BP: should be imported in the future, but I need it now to demonstrate how to define intraperitoneal injection",obsolete_peritoneum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000002,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000228,,,,,,,,,,,,,,,,,,OBI:0000323,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_peritoneum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200031,differential expression analysis objective,,"A differential expression analysis objective is a data transformation objective whose input consists of expression levels of entities (such as transcripts or proteins), or of sets of such expression levels, under two or more conditions and whose output reflects which of these are likely to have different expression across such conditions.",false,,,http://purl.obolibrary.org/obo/OBI_0200166,,,,,,,,,,,,,,,,,,,"A differential expression analysis objective is a data transformation objective whose input consists of expression levels of entities (such as transcripts or proteins), or of sets of such expression levels, under two or more conditions and whose output reflects which of these are likely to have different expression across such conditions.",PERSON: Elisabetta Manduchi,,,,,,differential expression analysis objective,,"Analyses implemented by the SAM (http://www-stat.stanford.edu/~tibs/SAM), PaGE (www.cbil.upenn.edu/PaGE) or GSEA (www.broad.mit.edu/gsea/) algorithms and software",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200031,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,differential expression analysis objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0000171,autotransplantation,,is the transplantation of tissue from one part of \nthe body to another in the same individual. ),false,,,http://purl.obolibrary.org/obo/OBI_0000105,,,,,,,,,,,,,,,,,,,is the transplantation of tissue from one part of \nthe body to another in the same individual. ),OBI branch derived,,,,,,autotransplantation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000171,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,autotransplantation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0001299,intracellular cytokine staining assay measuring epitope specific interleukin-5 production by T cells,IL-5 release|ICS,An assay of epitope specific interleukin-5 production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001230,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-5 production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-5 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001299,,,,,,,,,,,,,,,,,,,,,,,,IL-5 release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-5 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001452,cell culture analyte detection bioassay measuring epitope specific tumor necrosis factor production by T cells,TNFa release|bioassay,A T cell epitope specific tumor necrosis factor production assay that uses a cell culture analyte detection bioassay.,false,,,http://purl.obolibrary.org/obo/OBI_0001416,,,,,,,,,,,,,,,,,,,A T cell epitope specific tumor necrosis factor production assay that uses a cell culture analyte detection bioassay.,IEDB,,,,,,cell culture analyte detection bioassay measuring epitope specific tumor necrosis factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001452,,,,,,,,,,,,,,,,,,,,,,,,TNFa release|bioassay,,,,,,,,,,,,,,,,,,,,,,cell culture analyte detection bioassay measuring epitope specific tumor necrosis factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000047,processed material,,Is a material entity that is created or changed during material processing.,false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,Is a material entity that is created or changed during material processing.,,,,,,,processed material,,"Examples include gel matrices, filter paper, parafilm and buffer solutions, mass spectrometer, tissue samples",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000047,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,processed material,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0001845,intracellular cytokine staining assay measuring epitope specific interleukin-15 production by T cells,IL-15 release|ICS,An assay of epitope specific interleukin-15 production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001292,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-15 production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-15 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001845,,,,,,,,,,,,,,,,,,,,,,,,IL-15 release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-15 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000749,CART,classification and regression trees,A CART (classification and regression trees) is a data transformation method for producing a classification or regression model with a tree-based structure.,false,,,http://purl.obolibrary.org/obo/OBI_0000707,,http://purl.obolibrary.org/obo/OBI_0000704,,classification and regression trees,,,,,,,,,,,,,,,A CART (classification and regression trees) is a data transformation method for producing a classification or regression model with a tree-based structure.,"BOOK: David J. Hand, Heikki Mannila and Padhraic Smyth (2001) Principles of Data Mining.",,,,,,CART,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000749,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CART,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0302905,elution,,the process of extracting one material from another by washing with a solvent to remove adsorbed material from an adsorbent (as in washing of loaded ion-exchange resins to remove captured ions),false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,the process of extracting one material from another by washing with a solvent to remove adsorbed material from an adsorbent (as in washing of loaded ion-exchange resins to remove captured ions),wordnet.princeton.edu/perl/webwn,,,,,,elution,,PMID: 18549238.Theory and Application of the Two-Mode Gradient Elution in Liquid Chromatography Involving Simultaneous Changes in Temperature and Mobile-Phase Composition.Anal Chem. 2008 Jun 13.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000038,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000318,,,OBI:0302905,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,elution,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001820,epitope specific chemokine (C-X-C motif) ligand 16 production by T cells,,A process of chemokine (C-X-C motif) ligand 16 production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0097392|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,Date: 2012-11-16; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mappings: MMExpressionsTcell.txt,,A process of chemokine (C-X-C motif) ligand 16 production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific chemokine (C-X-C motif) ligand 16 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001820,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific chemokine (C-X-C motif) ligand 16 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/UBERON_0002067,dermis,,"The dermis is a layer of skin between the epidermis (with which it makes up the skin) and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis[WP].",false,,,http://purl.obolibrary.org/obo/CARO_0000055,,,,,,,,,,,,,,,,,,,"The dermis is a layer of skin between the epidermis (with which it makes up the skin) and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis[WP].",,,,,,,dermis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UBERON:0002067,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uberon.owl,,,,,,,,,,,,,,,,,,,dermis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200019,loess group transformation two-channel,,A loess group transformation two-channel is a loess group transformation in the special case where the input is the result of an MA transformation applied to intensities from the two channels of a two-channel assay.,false,,,http://purl.obolibrary.org/obo/OBI_0200024,,,,,,,,,,,,,,,,,,,A loess group transformation two-channel is a loess group transformation in the special case where the input is the result of an MA transformation applied to intensities from the two channels of a two-channel assay.,OTHER: Editor's generalization based on MGED Ontology term,,,,,,loess group transformation two-channel,,A loess group transformation two-channel is a loess group transformation in the special case where the input is the result of an MA transformation applied to intensities from the two channels of a two-channel assay.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200019,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,loess group transformation two-channel,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/GO_0071606,chemokine (C-C motif) ligand 4 production,,"The appearance of chemokine (C-C motif) ligand 4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0032602,,,,,,,,,,,,,,,,,,,"The appearance of chemokine (C-C motif) ligand 4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,chemokine (C-C motif) ligand 4 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0071606,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,chemokine (C-C motif) ligand 4 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0071607,macrophage inflammatory protein-1 gamma production,,"The appearance of macrophage inflammatory protein-1 gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0032602,,,,,,,,,,,,,,,,,,,"The appearance of macrophage inflammatory protein-1 gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,macrophage inflammatory protein-1 gamma production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0071607,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,macrophage inflammatory protein-1 gamma production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0071609,chemokine (C-C motif) ligand 5 production,,"The appearance of chemokine (C-C motif) ligand 5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0032602,,,,,,,,,,,,,,,,,,,"The appearance of chemokine (C-C motif) ligand 5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,chemokine (C-C motif) ligand 5 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0071609,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,chemokine (C-C motif) ligand 5 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0071604,transforming growth factor beta production,,"The appearance of any member of the transforming growth factor-beta family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Transforming growth factor-beta family members include TGF-B1, TGF-B2, and TGF-B3.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of any member of the transforming growth factor-beta family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Transforming growth factor-beta family members include TGF-B1, TGF-B2, and TGF-B3.",,,,,,,transforming growth factor beta production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0071604,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,transforming growth factor beta production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0071608,macrophage inflammatory protein-1 alpha production,,"The appearance of macrophage inflammatory protein 1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0032602,,,,,,,,,,,,,,,,,,,"The appearance of macrophage inflammatory protein 1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,macrophage inflammatory protein-1 alpha production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0071608,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,macrophage inflammatory protein-1 alpha production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0071605,monocyte chemotactic protein-1 production,,"The appearance of monocyte chemotactic protein-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0032602,,,,,,,,,,,,,,,,,,,"The appearance of monocyte chemotactic protein-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,monocyte chemotactic protein-1 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0071605,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,monocyte chemotactic protein-1 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001150,chromosomal substitution,,"A genetic transformation in which all, or part, of a chromosome from a donor replaces that of the recipient. It does not include chromosome recombination. For single gene insertion, use the term 'gene knock in'. ",false,,,http://purl.obolibrary.org/obo/OBI_0600043,,,,,,,,,,,,,,,,,,,"A genetic transformation in which all, or part, of a chromosome from a donor replaces that of the recipient. It does not include chromosome recombination. For single gene insertion, use the term 'gene knock in'. ",MO_995 chromosomal_substitution,,,,,,chromosomal substitution,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001150,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,chromosomal substitution,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000544,Bruker SampleRail system,,"This Instrument system automatically prepares an NMR sample, inserts it into an NMR magnet, performs NMR experiments on the sample, and transports it back to the preparation system.   The SampleRail fulfills the transporting tasks from the preparation system into the NMR magnet and back.",false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,NMR instrument,,"This Instrument system automatically prepares an NMR sample, inserts it into an NMR magnet, performs NMR experiments on the sample, and transports it back to the preparation system.   The SampleRail fulfills the transporting tasks from the preparation system into the NMR magnet and back.",WEB:<http://www.bruker-biospin.com/automation.html>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400207,,,,,,Bruker SampleRail system,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000383,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000544,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker SampleRail system,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0200127,weighted network graph construction,,A network graph construction in which an input data set describing objects and quantitative relationships between objects is transformed into and output representation of these objects as nodes and the quantitative relationships as weighted edges of a network graph.,false,,,http://purl.obolibrary.org/obo/OBI_0200126,,,,,,,,,,,,,,,,,,,A network graph construction in which an input data set describing objects and quantitative relationships between objects is transformed into and output representation of these objects as nodes and the quantitative relationships as weighted edges of a network graph.,PERSON: Richard Scheuermann,,,,,,weighted network graph construction,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200127,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,weighted network graph construction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Richard Scheuermann,,
http://purl.obolibrary.org/obo/OBI_0000231,enzymatic cleavage,,enzymatic cleavage is a protocol application to digest the fraction of input material that is susceptible to that enzyme,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,enzymatic cleavage is a protocol application to digest the fraction of input material that is susceptible to that enzyme,OBI branch derived,,,,,,enzymatic cleavage,,Polymorphism R62W results in resistance of CD23 to enzymatic cleavage in cultured cells. Genes Immun. 2007 Apr;8(3):215-23. Epub 2007 Feb 15. PMID: 17301828,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100051,,,,OBI:0000231,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,enzymatic cleavage,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0001721,3D structure determining assay of a 3D B cell epitope:antibody complex,3D structure|any method,A B cell epitope recognition assay that characterizes the 3D structure of an antibody / BCR with a ligand.,false,,,http://purl.obolibrary.org/obo/OBI_0600045|http://purl.obolibrary.org/obo/OBI_1110127,,,,,,,,,,,,,,,,,,,A B cell epitope recognition assay that characterizes the 3D structure of an antibody / BCR with a ligand.,IEDB,,,,,,3D structure determining assay of a 3D B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001721,,,,,,,,,,,,,,,,,,,,,,,,3D structure|any method,,,,,,,,,,,,,,,,,,,,,,3D structure determining assay of a 3D B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0302914,digital curation,,"Digital curation is the process of establishing and developing long term repositories of digital assets for current and future reference by researchers, scientists, and historians, and scholars generally.",false,,,http://purl.obolibrary.org/obo/IAO_0000572,,,,,,,,,,,,,,,,,,,"Digital curation is the process of establishing and developing long term repositories of digital assets for current and future reference by researchers, scientists, and historians, and scholars generally.",wikipedia,,,,,,digital curation,,PMID: 16901087. Supporting the curation of biological databases with reusable text mining.Genome Inform. 2005;16(2):32-44.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302914,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,digital curation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000552,reverse transcribed polymerase chain reaction,reverse transcription polymerase chain reaction|RT-PCR,reverse transcribe pcr is a process which allow amplification of cDNA during a pcr reaction while the cDNA results from a retrotranscription of messenger RNA isolated from a material entity.,false,,,http://purl.obolibrary.org/obo/OBI_0600058,,,,reverse transcription polymerase chain reaction|RT-PCR,,,,,,,,,,,,,,,reverse transcribe pcr is a process which allow amplification of cDNA during a pcr reaction while the cDNA results from a retrotranscription of messenger RNA isolated from a material entity.,,,,,,"3/21/10,  BP:Modified definition to clarify that this is not the assay, but the material transformation",reverse transcribed polymerase chain reaction,,"Harmonisation of multi-centre real-time reverse-transcribed PCR results of a candidate prognostic marker in breast cancer: an EU-FP6 supported study of members of the EORTC - PathoBiology Group.

Span PN, Sieuwerts AM, Heuvel JJ, Spyratos F, Duffy MJ, Eppenberger-Castori S, Vacher S, O'Brien K, McKiernan E, Pierce A, Vuaroqueaux V, Foekens JA, Sweep FC, Martens JW.
Eur J Cancer. 2009 Jan;45(1):74-81. PMID: 19008094",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_33697,http://purl.obolibrary.org/obo/OBI_0000406,,,OBI:0000552,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,reverse transcribed polymerase chain reaction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0200197,spectrum analysis objective,,is a data transformation objective where the aim is to analyse some aspect of spectral data by some data transformation process. ,false,,,http://purl.obolibrary.org/obo/OBI_0200166,,,,,,,,,,,,,,,,,,,is a data transformation objective where the aim is to analyse some aspect of spectral data by some data transformation process. ,,,,,,,spectrum analysis objective,,Calculation of characteristic path length in mass spectrometry,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200197,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,spectrum analysis objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Helen Parkinson|PERSON: Tina Boussard,,
http://purl.obolibrary.org/obo/CHEBI_42098,digoxigenin,,"A hydroxy steroid that consists of 5beta-cardanolide having a double bond at the 20(22)-position as well as hydroxy groups at the 3beta-, 12beta- and 14beta-positions. It has been isolated from the plant species of the genus Digitalis.",false,,,http://purl.obolibrary.org/obo/REO_0000280,,,,,,,,,,,,,,,,,,,"A hydroxy steroid that consists of 5beta-cardanolide having a double bond at the 20(22)-position as well as hydroxy groups at the 3beta-, 12beta- and 14beta-positions. It has been isolated from the plant species of the genus Digitalis.",,,,,,,digoxigenin,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/REO_0000171,,,,,,,,,,,,CHEBI:42098,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,digoxigenin,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0100063,cultured clonal cell population,clonal cell culture sample,"A cultured cell population comprised of cells which can all be traced back to a single ancestor cell, and which therefore can be treated as identical.",false,,,http://purl.obolibrary.org/obo/OBI_0100060,,,,clonal cell culture sample,,,,,,,,,,,,,,,"A cultured cell population comprised of cells which can all be traced back to a single ancestor cell, and which therefore can be treated as identical.",GROUP: OBI Biomaterial Branch,,,,,,cultured clonal cell population,,"cell cut
Stem cell functions assessed in clonal culture. Soc Gen Physiol Ser. 1988;43:39-45. Review. PMID: 3077557",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0100063,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cultured clonal cell population,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Susanna Sansone|PERSON:Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_0000706,SOLiD sequencing,,"is a DNA sequencing which allows sequence identification by relying on the following steps:
1. Primers hybridize to the P1 adapter sequence within the library template.
2. A set of four fluorescently labeled di-base probes compete for ligation to the sequencing primer. Specificity of the di-base probe is achieved by interrogating every 1st and 2nd base in each ligation reaction.
3. Multiple cycles of ligation, detection and cleavage are performed with the number of cycles determining the eventual read length.
4. Following a series of ligation cycles, the extension product is removed and the template is reset with a primer complementary to the n-1 position for a second round of ligation cycles",false,,,http://purl.obolibrary.org/obo/OBI_0000723,,,,,,,,,,,,,,,,,,,"is a DNA sequencing which allows sequence identification by relying on the following steps:
1. Primers hybridize to the P1 adapter sequence within the library template.
2. A set of four fluorescently labeled di-base probes compete for ligation to the sequencing primer. Specificity of the di-base probe is achieved by interrogating every 1st and 2nd base in each ligation reaction.
3. Multiple cycles of ligation, detection and cleavage are performed with the number of cycles determining the eventual read length.
4. Following a series of ligation cycles, the extension product is removed and the template is reset with a primer complementary to the n-1 position for a second round of ligation cycles",adapted from Wikipedia and Applied Biosystems web site,,,,,,SOLiD sequencing,,"PMID: 19119315. High-resolution analysis of the 5'-end transcriptome using a next generation DNA sequencer.  Hashimoto S, Qu W, Ahsan B, Ogoshi K, Sasaki A, Nakatani Y, Lee Y, Ogawa M, Ametani A, Suzuki Y, Sugano S, Lee CC, Nutter RC, Morishita S, Matsushima K. PLoS One. 2009;4(1):e4108.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000696,,,,,,,,,,,http://purl.obolibrary.org/obo/PR_000023089,,,,OBI:0000706,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,SOLiD sequencing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_1110032,HeLa cell line,,A cell line derived from human cervical cancer cells.,false,,,http://purl.obolibrary.org/obo/CLO_0009828,,,,,,,,,,,,,,,,,,,A cell line derived from human cervical cancer cells.,IEDB|http://www.biotech.ist.unige.it/cldb/cl1597.html,,,,,,HeLa cell line,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110032,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,HeLa cell line,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000185,imaging assay,,An imaging assay is an assay to produce a picture of an entity. definition_source: OBI.,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,http://purl.obolibrary.org/obo/OBI_0000441,,,,,,,,,,,,,,,,,An imaging assay is an assay to produce a picture of an entity. definition_source: OBI.,OBI branch derived,,,,,,imaging assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000101,,,OBI:0000185,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,imaging assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0001934,predicted value,,an information content entity that has been generated by a prediction process in which an estimate of a value of an entity is made which can be measured but without performing such a measurement. The value specification is intended to be close to the value a measurement process would produce modulo a prediction error.,false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,,,,,,,,,,,,,,,,an information content entity that has been generated by a prediction process in which an estimate of a value of an entity is made which can be measured but without performing such a measurement. The value specification is intended to be close to the value a measurement process would produce modulo a prediction error.,,,,,,,predicted value,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001933,,,,,,,,,,,,,,,,OBI:0001934,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,predicted value,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001570,biological activity assay measuring epitope specific vascular endothelial growth factor production by T cells,VEGF release|biological activity,A T cell epitope specific cytokine production assay that detects vascular endothelial growth factor production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects vascular endothelial growth factor production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific vascular endothelial growth factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001570,,,,,,,,,,,,,,,,,,,,,,,,VEGF release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific vascular endothelial growth factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0400011,avalanche photodiode,,"An avalanche photodiode is typically used to collect photons emitted by forward scatter because it is far less sensitive, and less likely o be burned out, than a PMT. A photodiode with high quantum efficiency and a mechanism for producing gains as high as a few thousand.",false,,,http://purl.obolibrary.org/obo/OBI_0400083,,,,,,,,,,,,,,,,,,,"An avalanche photodiode is typically used to collect photons emitted by forward scatter because it is far less sensitive, and less likely o be burned out, than a PMT. A photodiode with high quantum efficiency and a mechanism for producing gains as high as a few thousand.","Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253",,,,,,avalanche photodiode,,C30644E -  InGaAs Avalanche Photodiode,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400011,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,avalanche photodiode,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/IAO_0000408,length measurement datum,,A scalar measurement datum that is the result of measurement of length quality,false,,,http://purl.obolibrary.org/obo/IAO_0000032,,,,,,,,,,,,,,,,,,,A scalar measurement datum that is the result of measurement of length quality,,,,,,,length measurement datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,http://purl.obolibrary.org/obo/UO_0000001,,,,,,,,,,,,,,,,,,,,,IAO:0000408,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/PATO_0000122,,,,,,,,length measurement datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0400142,power supply,PSU|power pack|power supply unit|electrical power supply,A power supply is an device or part of a device that permits the required application of a defined electrical charge to an instrument. The power supply may permit the defined application of a given amount of current for a defined length of time.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,PSU|power pack|power supply unit|electrical power supply,,,,,,,,,,,,,"was power_pack, maps to SEP electrical_power_supply",,A power supply is an device or part of a device that permits the required application of a defined electrical charge to an instrument. The power supply may permit the defined application of a given amount of current for a defined length of time.,PERSON: Daniel Schober|sep:00093,,,,,,power supply,,A AC/DC transformer that generates the reqired power for an electrophoresis apparatus,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,http://purl.obolibrary.org/obo/OBI_0000384,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400142,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,power supply,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Daniel Schober|Frank Gibson,,
http://purl.obolibrary.org/obo/OBI_0001869,Illumina BeadChip,,An array that consists of 3-micron silica beads that self assemble in microwells on either of two materials: fiber optic bundles or planar silica slides.,false,,,http://purl.obolibrary.org/obo/OBI_0001865,,,,,,,,,,,,,,,,,,,An array that consists of 3-micron silica beads that self assemble in microwells on either of two materials: fiber optic bundles or planar silica slides.,http://www.illumina.com/technology/beadarray_technology.ilmn,,,,,,Illumina BeadChip,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001869,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Illumina BeadChip,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng, Alan Ruttenberg, Venkat Malladi",,
http://purl.obolibrary.org/obo/OBI_0001276,biological activity assay measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells,CCL1/TCA-3 release|biological activity,A T cell epitope specific cytokine production assay that detects production of chemokine (C-C motif) ligand 1 by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects production of chemokine (C-C motif) ligand 1 by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001276,,,,,,,,,,,,,,,,,,,,,,,,CCL1/TCA-3 release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001085,radiography instrument,,An image acquisition device that uses ionizing electromagnetic radiation such as X-rays to view objects.,false,,,http://purl.obolibrary.org/obo/OBI_0000398,,,,,,,,,,,,,,,,,,,An image acquisition device that uses ionizing electromagnetic radiation such as X-rays to view objects.,http://en.wikipedia.org/wiki/Medical_radiography,,,,,,radiography instrument,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453|http://purl.obolibrary.org/obo/OBI_0000397,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001085,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,radiography instrument,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_1110045,disposition to be bound by an adaptive immune receptor,epitope disposition,Is the disposition borne by a material entity that is realized in a process of being bound by a adaptive immune receptor.,false,,,http://purl.obolibrary.org/obo/BFO_0000016,,,,epitope disposition,,,,,,,,,,,,,,,Is the disposition borne by a material entity that is realized in a process of being bound by a adaptive immune receptor.,IEDB,,,,,,disposition to be bound by an adaptive immune receptor,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110045,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,disposition to be bound by an adaptive immune receptor,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0400040,FACSAria,,"A FASCSAria is a flow_cytometer_sorter manufactured by Becton Dickinson. It features digital electronics, a solid state 488 nm blue laser, a solid state 407 nm violet laser, and a HeNe (633 nm) ion laser. The Aria has the filters and PMTs to collect side scatter and 9 fluorescent parameters. The Aria has a photodiode detector for forward scatter collector. The flow cell is Quartz cuvette. The FACSAria is a sorter used to collect and analyse cells using up to 11 parameters.",false,,,http://purl.obolibrary.org/obo/OBI_0400099,,,,,,,,,,,,,,,,,,,"A FASCSAria is a flow_cytometer_sorter manufactured by Becton Dickinson. It features digital electronics, a solid state 488 nm blue laser, a solid state 407 nm violet laser, and a HeNe (633 nm) ion laser. The Aria has the filters and PMTs to collect side scatter and 9 fluorescent parameters. The Aria has a photodiode detector for forward scatter collector. The flow cell is Quartz cuvette. The FACSAria is a sorter used to collect and analyse cells using up to 11 parameters.",http://www.bdbiosciences.com/external_files/is/doc/mkt_lit/brochures/SJ-0003-00Aria.pdf,,,,,,FACSAria,,FACSAria at TSRI Flow Cytometry Core Facility,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400040,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,FACSAria,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0001414,biological activity assay measuring epitope specific interferon-gamma production by T cells,IFNg release|biological activity,A T cell epitope specific cytokine production assay that detects interferon-gamma production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects interferon-gamma production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific interferon-gamma production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001414,,,,,,,,,,,,,,,,,,,,,,,,IFNg release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific interferon-gamma production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001530,data service,,A service that has some information content entity as input and output.|Information content entity was used as specified input and output since it was more appropriate then data item or dataset.,false,,,http://purl.obolibrary.org/obo/OBI_0001173,,,,,,,,,,,,,,,,,,,A service that has some information content entity as input and output.,PERSON: Carlo Torniai,,,,,,data service,,Data analysis service such statistical abalysis or storage service such data  backup.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000030,http://purl.obolibrary.org/obo/IAO_0000030,,,OBI:0001530,,,,,,,,,,,,,,,,,,Information content entity was used as specified input and output since it was more appropriate then data item or dataset.,,,,,,,,,,,,,,,,,,,,,,,,,,,,data service,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Carlo Torniai|PERSON: Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_0001665,cell bound MHC direct binding assay measuring the off rate [koff] of a MHC:ligand complex using fluorescence detection,off rate|cellular MHC/direct/fluorescence|1/s,A cell bound MHC ligand binding off rate measurement (koff) determination assay that uses fluorescence detection to measure direct ligand binding.,false,,,http://purl.obolibrary.org/obo/OBI_0001499|http://purl.obolibrary.org/obo/OBI_0001993,,,,,,,,,,,,,,,,,,,A cell bound MHC ligand binding off rate measurement (koff) determination assay that uses fluorescence detection to measure direct ligand binding.,IEDB,,,,,,cell bound MHC direct binding assay measuring the off rate [koff] of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001665,,,,,,,,,,,,,,,,,,,,,,,,off rate|cellular MHC/direct/fluorescence|1/s,,,,,,,,,,,,,,,,,,,,,,cell bound MHC direct binding assay measuring the off rate [koff] of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000532,column cartridge,,A device that binds the chromatography column and additional connector elements and / or valves or syringes into one physical unity for further processing.,false,,,http://purl.obolibrary.org/obo/OBI_0000048,,,,,,,,,,,,,,,,,"chromatography device, check on definition !",,A device that binds the chromatography column and additional connector elements and / or valves or syringes into one physical unity for further processing.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01055,,,,,,column cartridge,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000532,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,column cartridge,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001101,electronic repeater pipette,,A micropipette that can be programmed by the user to aspirate a volume of liquid reagent or sample and dispense a series of aliquots in successive dispensing operations.,false,,,http://purl.obolibrary.org/obo/OBI_0001128,,,,,,,,,,,,,,,,,,,A micropipette that can be programmed by the user to aspirate a volume of liquid reagent or sample and dispense a series of aliquots in successive dispensing operations.,http://www.faqs.org/patents/app/20090196797,,,,,,electronic repeater pipette,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001101,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,electronic repeater pipette,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001388,biological activity assay measuring epitope specific interleukin-1 alpha production by T cells,IL-1a release|biological activity,A T cell epitope specific cytokine production assay that detects interleukin-1 alpha production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects interleukin-1 alpha production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific interleukin-1 alpha production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001388,,,,,,,,,,,,,,,,,,,,,,,,IL-1a release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific interleukin-1 alpha production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000935,micromanipulator,,"A device that is used to physically interact with a sample under
a microscope, where a level of precision of movement is necessary that
cannot be achieved by the unaided human hand.",false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,"A device that is used to physically interact with a sample under
a microscope, where a level of precision of movement is necessary that
cannot be achieved by the unaided human hand.",http://en.wikipedia.org/wiki/Micromanipulator,,,,,,micromanipulator,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000379,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000935,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,micromanipulator,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Bjoern Peters,,
http://purl.obolibrary.org/obo/CHEBI_27889,lead(0),,An elemental lead that has formula Pb.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,An elemental lead that has formula Pb.,,,,,,,lead(0),,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:27889,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,lead(0),,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000480,Bruker high resolution probe,HR Probe,"BRUKER BIOSPIN's experienced Research & Development group not only delivers top-performance probes for the more common experiments, but also a wealth of special probes for almost any application. For high resolution (HR) NMR we offer probes with a variety of important characteristics and features.",false,,,http://purl.obolibrary.org/obo/OBI_0000561,,,,HR Probe,,,,,,,,,,,,,NMR probe,,"BRUKER BIOSPIN's experienced Research & Development group not only delivers top-performance probes for the more common experiments, but also a wealth of special probes for almost any application. For high resolution (HR) NMR we offer probes with a variety of important characteristics and features.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400223,,,,,,Bruker high resolution probe,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000480,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker high resolution probe,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001897,organization of sequencing facility contact person,Sequencing Facility Contact's Institution,An organization that is the affiliation of the contact representative at the sequencing facility,false,,,http://purl.obolibrary.org/obo/OBI_0000245,,,,,,,,,,,,,,,,,,,An organization that is the affiliation of the contact representative at the sequencing facility,NIAID GSCID-BRC metadata working group,,,,,,organization of sequencing facility contact person,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001897,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,organization of sequencing facility contact person,,,,,,Sequencing Facility Contact's Institution,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000805,antithrombin-III (AT-III) berichrome assay,,"An antithrombin-III (AT-III) assay in which exogenous bovine thrombin and heparin are added to test plasma to form a thrombin-heparin-AT complex. The residual thrombin not bound then hydrolyzes the p-nitroalanine substrate to produce a yellow color, which is read at 405 nm. The intensity of color produced is inversely proportional to the AT present. A calibration is done with standard human plasma reagent and results for a given specimen are reported as a percentage relative to the standard",false,,,http://purl.obolibrary.org/obo/OBI_0000787,,,,,,,,,,,,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,,"An antithrombin-III (AT-III) assay in which exogenous bovine thrombin and heparin are added to test plasma to form a thrombin-heparin-AT complex. The residual thrombin not bound then hydrolyzes the p-nitroalanine substrate to produce a yellow color, which is read at 405 nm. The intensity of color produced is inversely proportional to the AT present. A calibration is done with standard human plasma reagent and results for a given specimen are reported as a percentage relative to the standard",WEB:http://www.clinchem.org/cgi/content/full/43/9/1783@2009/08/06,,,,,todo Reagents from Berichrom(r) Antithrombin III (A) and standard human plasma,antithrombin-III (AT-III) berichrome assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000805,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,antithrombin-III (AT-III) berichrome assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001361,transcription profiling by RT-PCR assay,,An assay in which the transcriptome of a biological sample is analysed by reverse transcription PCR (RT-PCR),false,,,http://purl.obolibrary.org/obo/OBI_0000424,,http://purl.obolibrary.org/obo/OBI_0001331,,,,,,,,,,,,,,,,,An assay in which the transcriptome of a biological sample is analysed by reverse transcription PCR (RT-PCR),EFO_0002943: transcription profiling by RT-PCR,,,,,,transcription profiling by RT-PCR assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000552,http://purl.obolibrary.org/obo/OBI_0000989,,,,,,,,,,,,,,,OBI:0001361,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,transcription profiling by RT-PCR assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Anna Farne,,
http://purl.obolibrary.org/obo/OBI_0200125,data combination,data pooling,A data transformation in which individual input data elements and values are merged together into a output set of data elements and values.,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,http://purl.obolibrary.org/obo/OBI_0200189,,data pooling,,,,,,,,,,,,,,,A data transformation in which individual input data elements and values are merged together into a output set of data elements and values.,editor,,,,,,data combination,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,data combination,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Richard Scheuermann,,
http://purl.obolibrary.org/obo/OBI_0400091,cytometer sample tube,,"A particle delivery vessel. The cytometer sample tube is a vessel in which the sample is introduced to the cytometer. Frequently the tube is placed on the cytometer in such a manner that a seal is formed between the tube and cytometer, and gas is used to create enough pressure to push the sample out of the tube and into the cytometer.",false,,,http://purl.obolibrary.org/obo/OBI_0000836,,,,,,,,,,,,,,,,,,,"A particle delivery vessel. The cytometer sample tube is a vessel in which the sample is introduced to the cytometer. Frequently the tube is placed on the cytometer in such a manner that a seal is formed between the tube and cytometer, and gas is used to create enough pressure to push the sample out of the tube and into the cytometer.","Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253",,,,,,cytometer sample tube,,sample tube in a cytometer,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400091,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cytometer sample tube,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0002020,epigenetic modification assay,,"An assay that identifies epigenetic modification including histone modifications, open chromatin, and DNA methylation.",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,"An assay that identifies epigenetic modification including histone modifications, open chromatin, and DNA methylation.",Penn group,,,,,,epigenetic modification assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002020,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epigenetic modification assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Beta Cell Biology Consoritum,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/CHEBI_17234,glucose,,An aldohexose used as a source of energy and metabolic intermediate.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,An aldohexose used as a source of energy and metabolic intermediate.,,,,,,,glucose,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:17234,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,glucose,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0400108,heating block,,A heating block is an instrument or part of an instrument which raises or maintains the temperature of a sample to a defined constant temperature during certain parts of an assay,false,,,http://purl.obolibrary.org/obo/OBI_0001034,,,,,,,,,,,,,,,,,,,A heating block is an instrument or part of an instrument which raises or maintains the temperature of a sample to a defined constant temperature during certain parts of an assay,MO,,,,,,heating block,,An instrument used to heat and/or maintain material at a set temperature.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/OBI_0000371,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400108,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,heating block,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000811,primary structure of DNA macromolecule,,a quality of a DNA molecule that inheres in its bearer due to the order of its DNA nucleotide residues.,false,,,http://purl.obolibrary.org/obo/SO_0000001,,,,,,,,,,,,,,,,,,,a quality of a DNA molecule that inheres in its bearer due to the order of its DNA nucleotide residues.,,,,,,placeholder for SO,primary structure of DNA macromolecule,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000811,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,primary structure of DNA macromolecule,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BP et al,,
http://purl.obolibrary.org/obo/OBI_0001667,purified MHC competitive binding assay measuring equilibrium dissociation constant [KD] of a MHC:ligand complex approximated by IC50 using fluorescence detection,dissociation constant KD (~IC50)|purified MHC/competitive/fluorescence|nM,A purified MHC ligand binding equilibrium dissociation constant (KD) determination assay that uses fluorescence detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation and provides IC50 values determined under assay conditions where the IC50 approximates a KD value. ,false,,,http://purl.obolibrary.org/obo/OBI_0001537,,,,,,,,,,,,,,,,,,,A purified MHC ligand binding equilibrium dissociation constant (KD) determination assay that uses fluorescence detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation and provides IC50 values determined under assay conditions where the IC50 approximates a KD value. ,IEDB,,,,,,purified MHC competitive binding assay measuring equilibrium dissociation constant [KD] of a MHC:ligand complex approximated by IC50 using fluorescence detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001501,,,,,,,,,,,,,,,,OBI:0001667,,,,,,,,,,,,,,,,,,,,,,,,dissociation constant KD (~IC50)|purified MHC/competitive/fluorescence|nM,,,,,,,,,,,,,,,,,,,,,,purified MHC competitive binding assay measuring equilibrium dissociation constant [KD] of a MHC:ligand complex approximated by IC50 using fluorescence detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000915,freezing storage,,A storage process in temperature that maintenance the frozen status of the stored entities.,false,,,http://purl.obolibrary.org/obo/OBI_0302893,,http://purl.obolibrary.org/obo/OBI_0000806,,,,,,,,,,,,,,,,,A storage process in temperature that maintenance the frozen status of the stored entities.,MO_481 frozen_storage|OBI,,,,,"2010/3/3 Alan Ruttenberg: There is a question of whether we should have a separate objective to ""prepare for maintenance""
2014/2/3 OBI dev call: ""prepare for maintenance"" is a separate process. For example, 'freezing' and 'flash freezing' are defined and can be used to produce frozen material for storage.
Updated both textual and logical definition. Both input and output material of freezing storage have quality frozen.",freezing storage,,a fozen pellet used for later assay,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000915,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,freezing storage,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Alan Ruttenberg, Mathias Brochhausen",,
http://purl.obolibrary.org/obo/OBI_0100055,obsolete_cell line cell,,A material entity that represents generations of a primary culture.,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,A material entity that represents generations of a primary culture.,GROUP: OBI Biomaterial Branch,,,,,had superclass axiom: is_specified_output_of some 'establishing cell culture',obsolete_cell line cell,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000228,,,,,,,,,,,,,,,,,,OBI:0100055,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_cell line cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Susanna Sansone,http://purl.obolibrary.org/obo/CL_0007014,
http://purl.obolibrary.org/obo/OBI_0000859,cytoplasmic RNA extraction,,A RNA extraction process in which the desired output material is RNA in the cytoplasm.,false,,,http://purl.obolibrary.org/obo/OBI_0666666,,,,,,,,,,,,,,,,,,,A RNA extraction process in which the desired output material is RNA in the cytoplasm.,UPenn Group,,,,,,cytoplasmic RNA extraction,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000859,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cytoplasmic RNA extraction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jie Zheng|Person: Chris Stoeckert,,
http://purl.obolibrary.org/obo/CHEBI_59054,N-methylisatoic anhydride,,"A 3,1-benzoxazin-1,4-dione having an N-methyl substituent.",false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,"A 3,1-benzoxazin-1,4-dione having an N-methyl substituent.",,,,,,,N-methylisatoic anhydride,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:59054,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,N-methylisatoic anhydride,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000992,DNA sequencing service,,A DNA sequencing  process provided as a service - which is the realization of some DNA sequencing in which the service provider role is realized.,false,,,http://purl.obolibrary.org/obo/OBI_0001904,,,,,,,,,,,,,,,,,,,A DNA sequencing  process provided as a service - which is the realization of some DNA sequencing in which the service provider role is realized.,,,,,,Eagle-i will supply better English definition,DNA sequencing service,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000992,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNA sequencing service,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000626,,,,,,http://purl.obolibrary.org/obo/OBI_0000947|http://purl.obolibrary.org/obo/OBI_0000941,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001026,NMIA RNA structure mapping assay,single nucleotide resolution mapping assay using NMIA probe|SHAPE mapping assay,a single-nucleotide-resolution ribonucleic acid structure mapping assay which uses NMIA as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,false,,,http://purl.obolibrary.org/obo/OBI_0001017,,http://purl.obolibrary.org/obo/OBI_0000441,,single nucleotide resolution mapping assay using NMIA probe|SHAPE mapping assay,,,,,,,,,,,,,,,a single-nucleotide-resolution ribonucleic acid structure mapping assay which uses NMIA as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,RNA ontology,,,,,,NMIA RNA structure mapping assay,,PMID: 15796531,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_33697,,,,OBI:0001026,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NMIA RNA structure mapping assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001284,cytometric bead array assay measuring epitope specific interleukin-12 production by T cells,IL-12 release|cytometric bead array,An assay of epitope specific interleukin-12 production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001391,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-12 production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific interleukin-12 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001284,,,,,,,,,,,,,,,,,,,,,,,,IL-12 release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific interleukin-12 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001718,assay measuring the on rate [kon] of a B cell epitope:antibody complex,on rate|binding assay|M^-1s^-1,A B cell epitope binding constant determination assay that measures the on rate.,false,,,http://purl.obolibrary.org/obo/OBI_0001709,,,,,,,,,,,,,,,,,,,A B cell epitope binding constant determination assay that measures the on rate.,IEDB,,,,,,assay measuring the on rate [kon] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001718,,,,,,,,,,,,,,,,,,,,,,,,on rate|binding assay|M^-1s^-1,,,,,,,,,,,,,,,,,,,,,,assay measuring the on rate [kon] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/GO_0019815,B cell receptor complex,,"An immunoglobulin complex that is present in the plasma membrane of B cells and that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.",false,,,http://purl.obolibrary.org/obo/OBI_1110022,,,,,,,,,,,,,,,,,,,"An immunoglobulin complex that is present in the plasma membrane of B cells and that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.",,,,,,,B cell receptor complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0019815,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,B cell receptor complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0019814,immunoglobulin complex,,"A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.",false,,,http://purl.obolibrary.org/obo/GO_0043234,,,,,,,,,,,,,,,,,,,"A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.",,,,,,,immunoglobulin complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0019814,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,immunoglobulin complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200010,loess scale group transformation one-channel,,"A loess scale group transformation one-channel is a loess scale group transformation consisting in the application of a scale adjustment following a loess group transformation one-channel, to render the M group variances similar.",false,,,http://purl.obolibrary.org/obo/OBI_0200025,,,,,,,,,,,,,,,,,,,"A loess scale group transformation one-channel is a loess scale group transformation consisting in the application of a scale adjustment following a loess group transformation one-channel, to render the M group variances similar.",OTHER: Editor's adjustment based on MGED Ontology term,,,,,,loess scale group transformation one-channel,,Loess scale group normalization applied to data from two one-channel expression microarray assays.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200010,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,loess scale group transformation one-channel,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0002003,MiSeq,Illumina MiSeq,"A DNA sequencer which is manufactured by the Illumina corporation. Built upon sequencing by synthesis technology, the machine provides an end-to-end solution (cluster generation, amplification, sequencing, and data analysis) in a single machine.",false,,,http://purl.obolibrary.org/obo/OBI_0400103,,,,Illumina MiSeq,,,,,,,,,,,,,,,"A DNA sequencer which is manufactured by the Illumina corporation. Built upon sequencing by synthesis technology, the machine provides an end-to-end solution (cluster generation, amplification, sequencing, and data analysis) in a single machine.",http://res.illumina.com/documents/products/datasheets/datasheet_miseq.pdf,,,,,,MiSeq,,"Rutvisuttinunt W, Chinnawirotpisan P, Simasathien S, Shrestha SK, Yoon IK, Klungthong C, Fernandez S. Simultaneous and complete genome sequencing of influenza A and B with high coverage by Illumina MiSeq Platform. J Virol Methods. 2013 Nov;193(2):394-404. [PMID:23856301]",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002003,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,MiSeq,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"PERSON: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000942,intradermal injection,,is the injection of a material entity (bearing the administered substance role) into the dermis (bearing the target role) of an organism using a syringe,false,,,http://purl.obolibrary.org/obo/OBI_0000426|http://purl.obolibrary.org/obo/OBI_0600007,,http://purl.obolibrary.org/obo/OBI_0000434,,,,,,,,,,,,,,,,,is the injection of a material entity (bearing the administered substance role) into the dermis (bearing the target role) of an organism using a syringe,,,,,,,intradermal injection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000942,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,intradermal injection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0000589,chromatography pump system,,"Better flow rates can be achieved by using a pump or by using compressed gas (e.g. air, nitrogen, or argon) to push the solvent through the column (flash column chromatography).",false,,,http://purl.obolibrary.org/obo/OBI_0000485,,,,,,,,,,,,,,,,,,,"Better flow rates can be achieved by using a pump or by using compressed gas (e.g. air, nitrogen, or argon) to push the solvent through the column (flash column chromatography).",WEB:<http://en.wikipedia.org/wiki/Column_chromatography>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01046,,,,,,chromatography pump system,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000589,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,chromatography pump system,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0002064,detection of specific nucleic acids with complementary probes assay measuring epitope specific granzyme A release by T cells,granzyme A release|RNA/DNA detection,A T cell epitope specific granzyme A release assay that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001809,,,,,,,,,,,,,,,,,,,A T cell epitope specific granzyme A release assay that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific granzyme A release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002064,,,,,,,,,,,,,,,,,,,,,,,,granzyme A release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific granzyme A release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001674,cap analysis of gene expression ,CAGE,"An assay which aims at monitoring RNA transcript abundances in biological samples by extracting 5' ends of capped transcripts, RTPCR and sequence those. Copy numbers of CAGE tags provide  a way of quantification and provide a measure of expression of the transcriptome ",false,,,http://purl.obolibrary.org/obo/OBI_0600047|http://purl.obolibrary.org/obo/OBI_0000424,,http://purl.obolibrary.org/obo/OBI_0001331,,CAGE,,,,,,,,,,,,,,,"An assay which aims at monitoring RNA transcript abundances in biological samples by extracting 5' ends of capped transcripts, RTPCR and sequence those. Copy numbers of CAGE tags provide  a way of quantification and provide a measure of expression of the transcriptome ",PMID:14663149,,,,,,cap analysis of gene expression ,,"5' end-centered expression profiling using cap-analysis gene expression and next-generation sequencing.
Takahashi H, Lassmann T, Murata M, Carninci P.
Nat Protoc. 2012 Feb 23;7(3):542-61. doi: 10.1038/nprot.2012.005.
PMID: 22362160",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000552|http://purl.obolibrary.org/obo/OBI_0000626,http://purl.obolibrary.org/obo/OBI_0400103,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000880,,,,OBI:0001674,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cap analysis of gene expression ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra; Marcus Chibucos,,
http://purl.obolibrary.org/obo/PATO_0001233,dorsal to,,A spatial quality inhering in a bearer by virtue of the bearer's being located toward the back or upper surface of an organism relative to another entity.,false,,,http://purl.obolibrary.org/obo/PATO_0001631,,,,,,,,,,,,,,,,,,,A spatial quality inhering in a bearer by virtue of the bearer's being located toward the back or upper surface of an organism relative to another entity.,,,,,,,dorsal to,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001233,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,dorsal to,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0001237,quality of a single physical entity,,A physical object quality which inheres in a single-bearer.,false,,,http://purl.obolibrary.org/obo/BFO_0000019,,,,,,,,,,,,,,,,,,,A physical object quality which inheres in a single-bearer.,,,,,,,quality of a single physical entity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001237,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,quality of a single physical entity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0001238,quality of related physical entities,,A physical entity quality which exists in relation towards some other entity.,false,,,http://purl.obolibrary.org/obo/BFO_0000019,,,,,,,,,,,,,,,,,,,A physical entity quality which exists in relation towards some other entity.,,,,,,,quality of related physical entities,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001238,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,quality of related physical entities,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001235,transcription profiling by tiling array assay,,An assay in which the transcriptome of a biological sample is analysed using a tiling path array.,false,,,http://purl.obolibrary.org/obo/OBI_0000424,,http://purl.obolibrary.org/obo/OBI_0001331,,,,,,,,,,,,,,,,,An assay in which the transcriptome of a biological sample is analysed using a tiling path array.,EFO_0002769 transcription profiling by tiling array,,,,,,transcription profiling by tiling array assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001307,,,,,,,,,,,,,,,OBI:0001235,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,transcription profiling by tiling array assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: James Malone,,
http://purl.obolibrary.org/obo/SO_0001248,assembly,,A region of the genome of known length that is composed by ordering and aligning two or more different regions.,false,,,http://purl.obolibrary.org/obo/SO_0000001,,,,,,,,,,,,,,,,,,,A region of the genome of known length that is composed by ordering and aligning two or more different regions.,,,,,,,assembly,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,SO:0001248,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/so.owl,,,,,,,,,,,,,,,,,,,assembly,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000384,electricity supply function,power supply,"An electricity supply function is an energy supply function to transfer electricity from one source to another, typically a consumer of the electricity or as a stimulus during a neuroscience experiment.",false,,,http://purl.obolibrary.org/obo/OBI_0000391,,,,power supply,,,,,,,,,,,,,,,"An electricity supply function is an energy supply function to transfer electricity from one source to another, typically a consumer of the electricity or as a stimulus during a neuroscience experiment.",,,,,,,electricity supply function,,the function of supplying current during a neuroscience experiment.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000384,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,electricity supply function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Daniel Schober|Frank Gibson|Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0000264,obsolete_sample population,recruited population,"A sample population is an object aggregate that is selected from the population, e.g. the fish in the net that were sampled from the lake, the people that responded to the call for volunteers.",true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,recruited population,,,,,,,,,,,,,,,"A sample population is an object aggregate that is selected from the population, e.g. the fish in the net that were sampled from the lake, the people that responded to the call for volunteers.",GROUP: OBI Biomaterial Branch,,,,,"03/21/2010: BP, obsoleting this term, as it is duplicated by 'material sample'. Use that instead term instead, which now also has 'sample population' as an alternative label.",obsolete_sample population,,Patterns of benzylpiperazine/trifluoromethylphenylpiperazine party pill use and adverse effects in a population sample in New Zealand. Drug Alcohol Rev. 2008 Mar 31:1-7.  PMID: 18608458,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000227,,,,,,,,,,,,,,,,,,OBI:0000264,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_sample population,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Jennifer Fostel|PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000691,ABI 377 automated sequencer,,is a DNA sequencer which is manufactured by Applied Biosystems corporation (formerly Perkin-Elmer). It allows automated chain termination DNA sequencing. It has part polyacrylamide gel electrophoresis system and a laser -based detection system to detect fluorescence intensity emitted by the dyes attached to the dideoxyterminator nucleotides or to the primers.,false,,,http://purl.obolibrary.org/obo/OBI_0400103,,,,,,,,,,,,,,,,,,,is a DNA sequencer which is manufactured by Applied Biosystems corporation (formerly Perkin-Elmer). It allows automated chain termination DNA sequencing. It has part polyacrylamide gel electrophoresis system and a laser -based detection system to detect fluorescence intensity emitted by the dyes attached to the dideoxyterminator nucleotides or to the primers.,Applied Biosystems,,,,,,ABI 377 automated sequencer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000691,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ABI 377 automated sequencer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0200012,loess scale group transformation two-channel,,"A loess scale group transformation two-channel is a loess scale group transformation consisting in the application of a scale adjustment following a loess group transformation two-channel, to render the M group variances similar.",false,,,http://purl.obolibrary.org/obo/OBI_0200025,,,,,,,,,,,,,,,,,,,"A loess scale group transformation two-channel is a loess scale group transformation consisting in the application of a scale adjustment following a loess group transformation two-channel, to render the M group variances similar.",OTHER: Adjusted from MGED Ontology,,,,,,loess scale group transformation two-channel,,Loess scale group normalization applied to data from a two-channel expression microarray assay.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200012,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,loess scale group transformation two-channel,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0000621,custom made column,,A custom made column ia a chromatography column which is specifically tailored according to the needs of the separation as requested by a scientist or working group.,false,,,http://purl.obolibrary.org/obo/OBI_0000038,,,,,,,,,,,,,,,,,,,A custom made column ia a chromatography column which is specifically tailored according to the needs of the separation as requested by a scientist or working group.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01234,,,,,,custom made column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000621,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,custom made column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0400119,microarray wash station,,a device that is used to wash Affymetrix-type arrays.,false,,,http://purl.obolibrary.org/obo/OBI_0001034,,,,,,,,,,,,,,,,,,,a device that is used to wash Affymetrix-type arrays.,MO_626 wash_station,,,,,,microarray wash station,,ArrayIt(r) Microarray Wash Station,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000401,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400119,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,microarray wash station,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Trish Whetzel,,
http://purl.obolibrary.org/obo/OBI_0200141,log base,logarithmic base|logarithm base,The log base is a feature of a logarithmic function which is defined in http://en.wikipedia.org/wiki/Logarithm. Its value can be any positive real number different from 1.,false,,,http://purl.obolibrary.org/obo/OBI_0200140,,,,logarithmic base|logarithm base,,,,,,,,,,,,,,,The log base is a feature of a logarithmic function which is defined in http://en.wikipedia.org/wiki/Logarithm. Its value can be any positive real number different from 1.,WEB: http://en.wikipedia.org/wiki/Logarithm,,,,,,log base,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200141,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,log base,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0000446,obsolete_identification,,a process by which the identity (what a thing is) of a material entity is established within a certain confidence interval,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,a process by which the identity (what a thing is) of a material entity is established within a certain confidence interval,,,,,,"Alan Ruttenberg 2010/11/22: After OBI call. A specific identification objective should be used instead, as necessary|See tracker:
https://sourceforge.net/tracker/index.php?func=detail&aid=3302925&group_id=177891&atid=886178",obsolete_identification,,"DNA cleavage assay for the identification of topoisomerase I inhibitors.
Nat Protoc. 2008;3(11):1736-50. PMID: 18927559",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000124,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,OBI:0000446,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_identification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000702,454 Genome Sequencer FLX,GS-FLX|454 GS FLX,"is a DNA sequencer which is manufactured by 454 Life Science Corporation and enables pyrosequencing to be performed. It comprises both optics and fluidics subsystems, which are
controlled by a computer subsystem. The fluidics subsystem ensures accurate reagent dispensing. It consists of a reagents cassette (which holds the reagent containers), a sipper manifold, pumps, valves, and debubblers. The fluidics subsystem flows the sequencing reagents across the wells of the PicoTiterPlate device, and moves the spent reagents from the PicoTiterPlate device to the waste receptacle. The optics subsystem consists of a CCD camera and a camera controller. The camera captures the light emitted in the wells of the PicoTiterPlate device during each step of the sequencing cycle, and sends the digital images to the computer subsystem for processing. The computer controls the other Sequencer subsystems, and processes the digital images sent by the camera to extract the DNA sequence information.",false,,,http://purl.obolibrary.org/obo/OBI_0400103,,,,GS-FLX|454 GS FLX,,,,,,,,,,,,,,,"is a DNA sequencer which is manufactured by 454 Life Science Corporation and enables pyrosequencing to be performed. It comprises both optics and fluidics subsystems, which are
controlled by a computer subsystem. The fluidics subsystem ensures accurate reagent dispensing. It consists of a reagents cassette (which holds the reagent containers), a sipper manifold, pumps, valves, and debubblers. The fluidics subsystem flows the sequencing reagents across the wells of the PicoTiterPlate device, and moves the spent reagents from the PicoTiterPlate device to the waste receptacle. The optics subsystem consists of a CCD camera and a camera controller. The camera captures the light emitted in the wells of the PicoTiterPlate device during each step of the sequencing cycle, and sends the digital images to the computer subsystem for processing. The computer controls the other Sequencer subsystems, and processes the digital images sent by the camera to extract the DNA sequence information.",adapted from https://www.roche-applied-science.com/servlet/RCProductDisplay?langId=-1&storeId=10202&productId=3.8.8.1.1.3&catalogId=10202&krypto=mgV8a0Sdps6%2BCXU8IoddmzNEyGgjde9j8MOFCiMzRsduELeenAlVZ%2FE1QR%2BxLpzNlqMZPLRHqaI%3D&ddkey=https:RCProductDisplay,,,,,,454 Genome Sequencer FLX,,"PMID: 18616967. The Genome Sequencer FLX System--longer reads, more applications, straight forward bioinformatics and more complete data sets.  Droege M, Hill B.
J Biotechnol. 2008 Aug 31;136(1-2):3-10.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000702,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,454 Genome Sequencer FLX,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000291,transcription factor binding site assay,TF binding,An assay with objective to find DNA region specifically recognized by proteins that function as transcription factors,false,,,http://purl.obolibrary.org/obo/OBI_0000070|http://purl.obolibrary.org/obo/OBI_0001146,,,,TF binding,,,,,,,,,,,,,,,An assay with objective to find DNA region specifically recognized by proteins that function as transcription factors,OBI,,,,,"JZ: fixed inconsistency issue and relabel the term
see tracker: https://sourceforge.net/p/obi/obi-terms/767/|JZ: add equivalent axiom for classification
add alternative term 'TF binding' which was used in BCBC database",transcription factor binding site assay,,"Transcription factor binding site identification in yeast: a comparison of high-density oligonucleotide and PCR-based microarray platforms.
Funct Integr Genomics. 2007 Oct;7(4):335-45. Epub 2007 Jul 19. PMID: 17638031",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000291,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,transcription factor binding site assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000826,treatment portion of study execution,,"A planned process, part of a study design execution, during which the treatment of subjects is ongoing",false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,,"A planned process, part of a study design execution, during which the treatment of subjects is ongoing",,,,,,09/28/2009 Alan Ruttenberg. Needed because we have to have a process to scope blinding over,treatment portion of study execution,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000471,OBI:0000826,http://purl.obolibrary.org/obo/OBI_0000471,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,treatment portion of study execution,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_1110167,ELISPOT assay measuring epitope specific interleukin-4 production by T cells,IL-4 release|ELISPOT,An assay of epitope specific interleukin-4 production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001450,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-4 production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific interleukin-4 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110167,,,,,,,,,,,,,,,,,,,,,,,,IL-4 release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific interleukin-4 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/GO_0070358,actin polymerization-dependent cell motility,,A process involved in the controlled movement of a bacterial cell powered by the continuous polymerization of actin at one pole of the cell.,false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,A process involved in the controlled movement of a bacterial cell powered by the continuous polymerization of actin at one pole of the cell.,,,,,,,actin polymerization-dependent cell motility,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0070358,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,actin polymerization-dependent cell motility,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001027,Terbium RNA structure mapping assay,single nucleotide resolution mapping assay using Terbium probe,a single-nucleotide-resolution nucleic acid structure mapping assay which uses Terbium as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,false,,,http://purl.obolibrary.org/obo/OBI_0001017,,http://purl.obolibrary.org/obo/OBI_0000441,,single nucleotide resolution mapping assay using Terbium probe,,,,,,,,,,,,,,,a single-nucleotide-resolution nucleic acid structure mapping assay which uses Terbium as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,RNA ontology,,,,,,Terbium RNA structure mapping assay,,PMID:10772868,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_33697,,,,OBI:0001027,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Terbium RNA structure mapping assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/GO_0010573,vascular endothelial growth factor production,,"The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,vascular endothelial growth factor production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0010573,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,vascular endothelial growth factor production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001318,proteomic profiling by array assay,,"An assay that proteins in a sample are detected, quantified or otherwise analysed, e.g. antibody profiling using an array based technology",false,,,http://purl.obolibrary.org/obo/OBI_0000443,,http://purl.obolibrary.org/obo/OBI_0000131,,,,,,,,,,,,,,,,,"An assay that proteins in a sample are detected, quantified or otherwise analysed, e.g. antibody profiling using an array based technology",EFO_0002765 proteomic profiling by array,,,,,,proteomic profiling by array assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0400149,,,,,,,,,,,,,,,OBI:0001318,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,proteomic profiling by array assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: James Malone,,
http://purl.obolibrary.org/obo/OBI_0001844,ELISPOT assay measuring epitope specific interleukin-12 production by T cells,IL-12 release|ELISPOT,An assay of epitope specific interleukin-12 production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001391,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-12 production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific interleukin-12 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001844,,,,,,,,,,,,,,,,,,,,,,,,IL-12 release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific interleukin-12 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001802,ELISPOT assay measuring epitope specific interleukin-3 production by T cells,IL-3 release|ELISPOT,An assay of epitope specific interleukin-3 production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001406,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-3 production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific interleukin-3 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001802,,,,,,,,,,,,,,,,,,,,,,,,IL-3 release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific interleukin-3 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/GO_0006306,DNA methylation,,The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.,false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.,,,,,,,DNA methylation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0006306,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,DNA methylation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001848,chromatin interaction analysis by paired-end tag sequencing,ChIA-PET assay|ChIA-PET,"An assay that incorporates chromatin immunoprecipitation (ChIP)-based enrichment, chromatin proximity ligation, Paired-End Tags, and high-throughput sequencing to determine de novo long-range chromatin interactions genome-wide.",false,,,http://purl.obolibrary.org/obo/OBI_0600047|http://purl.obolibrary.org/obo/OBI_0001956,,http://purl.obolibrary.org/obo/OBI_0000437|http://purl.obolibrary.org/obo/OBI_0001398,,ChIA-PET assay|ChIA-PET,,,,,,,,,,,,,,,"An assay that incorporates chromatin immunoprecipitation (ChIP)-based enrichment, chromatin proximity ligation, Paired-End Tags, and high-throughput sequencing to determine de novo long-range chromatin interactions genome-wide.",http://en.wikipedia.org/wiki/ChIA-PET,,,,,,chromatin interaction analysis by paired-end tag sequencing,,"Zhang, et al. ChIA-PET analysis of transcriptional chromatin interactions. Methods. 2012 Nov;58(3):289-99. [PMID:22926262]",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000800|http://purl.obolibrary.org/obo/OBI_0001852|http://purl.obolibrary.org/obo/OBI_0000690|http://purl.obolibrary.org/obo/OBI_0000626,http://purl.obolibrary.org/obo/OBI_0400103,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001573,,,OBI:0001848,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,chromatin interaction analysis by paired-end tag sequencing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000883,in vivo cell killing assay,,A cell killing assay that measures if and how many target cells are killed within an organism.,false,,,http://purl.obolibrary.org/obo/OBI_0000882,,,,,,,,,,,,,,,,,,,A cell killing assay that measures if and how many target cells are killed within an organism.,IEDB,,,,,,in vivo cell killing assay,,"Labeling two populations of cells with different levels of CFSE, pusling one population with an influenza peptide, injecting the cells into a mouse, and recoving cells 24 hours later. By comparing the recovery rate of cells with different CFSE labeling, it is possible to determine if there was specific killing of peptide pulsed target cells.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000883,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,in vivo cell killing assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/IAO_0000319,discussion section of a publication about an investigation,discussion section,A part of a publication about an investigation that is about the study interpretation of the investigation,false,,,http://purl.obolibrary.org/obo/IAO_0000314,,,,discussion section,,,,,,,,,,,,,,,A part of a publication about an investigation that is about the study interpretation of the investigation,,,,,,,discussion section of a publication about an investigation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000319,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,discussion section of a publication about an investigation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0001913,computation run time,computation run time datum,"computation run time is a time measurement datum which corresponds the time expressed in second, minute, hour necessary for a computer program to complete a process execution, for example genome assembly. It is an important metrics as it indicates the resource occupancy and computer program efficiency.
",false,,,http://purl.obolibrary.org/obo/IAO_0000416,,,,computation run time datum,,,,,,,,,,,,,,,"computation run time is a time measurement datum which corresponds the time expressed in second, minute, hour necessary for a computer program to complete a process execution, for example genome assembly. It is an important metrics as it indicates the resource occupancy and computer program efficiency.
","PRS,AGB",,,,,,computation run time,,"Gigascience. 2012 Dec 27;1(1):18. doi: 10.1186/2047-217X-1-18.
PMID: 23587118. 

See Table 4",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001913,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,computation run time,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Alejandra Gonzalez-Beltran|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/GO_0030097,hemopoiesis,,"The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.",false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,"The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.",,,,,,,hemopoiesis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0030097,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,hemopoiesis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_1110204,epitope specific killing by T cells,,A biological process where T cells lyse antigen presenting cells resulting from the recognition of a T cell epitope on MHC molecules of the antigen presenting cell.,false,,,http://purl.obolibrary.org/obo/GO_0001913,,,,,,,,,,,,,,,,,,,A biological process where T cells lyse antigen presenting cells resulting from the recognition of a T cell epitope on MHC molecules of the antigen presenting cell.,IEDB,,,,,,epitope specific killing by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110204,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific killing by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001371,epitope specific granzyme B production by T cells,,A process of granzyme B production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0071613,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of granzyme B production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific granzyme B production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001371,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific granzyme B production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000872,serum neutralization of viral infectivity assay,influenza neutralization assay,"A quantitative assay where different
dilutions of serum are mixed with virus and used to infect cells. At
the lower dilutions, antibodies will block infection, but at higher
dilutions, there will be too few antibodies to have an effect. The
simple process of dilution provides a way to compare the virus-
neutralizing abilities of different sera. The neutralization titer is
expressed as the reciprocal of the highest dilution at which virus
infection is blocked.",false,,,http://purl.obolibrary.org/obo/OBI_0000443,,http://purl.obolibrary.org/obo/OBI_0000437,,influenza neutralization assay,,,,,,,,,,,,,"MC, 20100217: I added influenza neutralization assay as alternative term. This should be tagged with a community specific value, eg ""influenza ontology"" or else.",,"A quantitative assay where different
dilutions of serum are mixed with virus and used to infect cells. At
the lower dilutions, antibodies will block infection, but at higher
dilutions, there will be too few antibodies to have an effect. The
simple process of dilution provides a way to compare the virus-
neutralizing abilities of different sera. The neutralization titer is
expressed as the reciprocal of the highest dilution at which virus
infection is blocked.",WEB: http://www.virology.ws/2009/05/28/influenza-microneutralization-assay/,,,,,,serum neutralization of viral infectivity assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000872,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,serum neutralization of viral infectivity assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person: Bjoern Peters|person: Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0001209,biological activity assay measuring epitope specific interleukin-10 production by T cells,IL-10 release|biological activity,A T cell epitope specific cytokine production assay that detects interleukin-10 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects interleukin-10 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific interleukin-10 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001209,,,,,,,,,,,,,,,,,,,,,,,,IL-10 release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific interleukin-10 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/GO_0001806,type IV hypersensitivity,,An inflammatory response driven by T cell recognition of processed soluble or cell-associated antigens leading to cytokine release and leukocyte activation.,false,,,http://purl.obolibrary.org/obo/GO_0002524,,,,,,,,,,,,,,,,,,,An inflammatory response driven by T cell recognition of processed soluble or cell-associated antigens leading to cytokine release and leukocyte activation.,,,,,,,type IV hypersensitivity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0001806,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,type IV hypersensitivity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001054,PET synthesizer,,A device that is used to produce targeted molecular pharmaceuticals for use in positron emission tomography.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A device that is used to produce targeted molecular pharmaceuticals for use in positron emission tomography.,PERSON: Erik Segerdell,,,,,,PET synthesizer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000376,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001054,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PET synthesizer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0302847,methylated polymer,,A methylated polymer which has artificially acquired one or more methyl groups,false,,,http://purl.obolibrary.org/obo/OBI_0000047|http://purl.obolibrary.org/obo/CHEBI_33839,,,,,,,,,,,,,,,,,,,A methylated polymer which has artificially acquired one or more methyl groups,OBI Biomaterial,,,,,,methylated polymer,,"Binding and penetration of methylated DNA into primary and transformed human cells.
Ann N Y Acad Sci. 2008 Aug;1137:36-40. PMID: 18837922",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302847,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,methylated polymer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000092,role of certified IRB professional,certified IRB professional,a role of which inheres in a Homo sapiens and realized during administration and oversight of the daily activities of Institutional Review Boards (IRBs) in the USA,false,,,http://purl.obolibrary.org/obo/OBI_0000016,,,,certified IRB professional,,,,,,,,,,,,,,,a role of which inheres in a Homo sapiens and realized during administration and oversight of the daily activities of Institutional Review Boards (IRBs) in the USA,WEB: http://en.wikipedia.org/wiki/Certified_IRB_Professional,,,,,,role of certified IRB professional,,CIP= Certified IRB Professional; http://acronyms.thefreedictionary.com/Certified+IRB+Professional,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000092,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,role of certified IRB professional,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Jennifer Fostel|Person:Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0000403,sort function,,A sort function is a function to distinguish material components based on some associated physical quality or entity and to partition the separate components into distinct fractions according to a defined order.,false,,,http://purl.obolibrary.org/obo/OBI_0000372,,,,,,,,,,,,,,,,,,,A sort function is a function to distinguish material components based on some associated physical quality or entity and to partition the separate components into distinct fractions according to a defined order.,,,,,,,sort function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000403,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sort function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Daniel Schober|Frank Gibson|Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0001476,phage display binding assay,,"A binding assay in which a collection of phages expressing a library of different peptides or protein fragnments is used to infect cells, followed by screening for cells that bind a protein of interest, and identifiying the sequence of infecting phages to determine a suitable binding partner.",false,,,http://purl.obolibrary.org/obo/OBI_0001146,,,,,,,,,,,,,,,,,,,"A binding assay in which a collection of phages expressing a library of different peptides or protein fragnments is used to infect cells, followed by screening for cells that bind a protein of interest, and identifiying the sequence of infecting phages to determine a suitable binding partner.",IEDB,,,,,,phage display binding assay,,"Using a commercial library of phages that produce random peptide sequences to infect E coli cells, and screening them for binding to a selecting antibody of unknown specificity. By iteratively using phages from selected E coli cells and repeating this process, phages encoding high affinity peptides for the antibody are selected, sequenced, and thereby the specificity of the antibody is elucidated.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001476,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,phage display binding assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/CL_0000010,cultured cell,,A cell in vitro that is or has been maintained or propagated as part of a cell culture.,false,,,http://purl.obolibrary.org/obo/CL_0000578,,,,,,,,,,,,,,,,,,,A cell in vitro that is or has been maintained or propagated as part of a cell culture.,,,,,,,cultured cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CL:0000010,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/cl.owl,,,,,,,,,,,,,,,,,,,cultured cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001045,capillary blotter,,"A device that is used to transfer nucleic acids from agarose gels onto a membrane, based on the movement of buffer from a reservoir through the gel and the blotting membrane to a stack of dry blotting paper by capillary force. The molecules are carried to the blotting membrane on which they are adsorbed.",false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,"A device that is used to transfer nucleic acids from agarose gels onto a membrane, based on the movement of buffer from a reservoir through the gel and the blotting membrane to a stack of dry blotting paper by capillary force. The molecules are carried to the blotting membrane on which they are adsorbed.",http://www.biometra.de/,,,,,,capillary blotter,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000383,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001045,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,capillary blotter,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/IAO_0000030,information content entity,,A generically dependent continuant that is about some thing.,false,,,http://purl.obolibrary.org/obo/BFO_0000031,,,,,,,,,,,,,,,,,,,A generically dependent continuant that is about some thing.,OBI_0000142,,,,,"information_content_entity 'is_encoded_in' some digital_entity in obi before split (040907). information_content_entity 'is_encoded_in' some physical_document in obi before split (040907).

Previous. An information content entity is a non-realizable information entity that 'is encoded in' some digital or physical entity.|2014-03-10: The use of ""thing"" is intended to be general enough to include universals and configurations (see https://groups.google.com/d/msg/information-ontology/GBxvYZCk1oc/-L6B5fSBBTQJ).",information content entity,,"Examples of information content entites include journal articles, data, graphical layouts, and graphs.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000030,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000001,,,,,,,,,,,,,,,,information content entity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0001180,half maximal effective concentration (EC50),,"half maximal effective concentration (EC50) is a scalar measurement datum corresponding to the concentration of a compound which induces a response halfway between the baseline and maximum after some specified exposure time. 
",false,,,http://purl.obolibrary.org/obo/IAO_0000032,,,,,,,,,,,,,,,,,,,"half maximal effective concentration (EC50) is a scalar measurement datum corresponding to the concentration of a compound which induces a response halfway between the baseline and maximum after some specified exposure time. 
",wikipedia,,,,,,half maximal effective concentration (EC50),,"Determining the potentency of a drug / antibody / toxicant by measuring a graded dose response curve, and determining the concentration of the compound where 50% of its maximal effect is observed. ",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,http://purl.obolibrary.org/obo/UO_0000051,,,,,,,,,,,,,,,,,,,,,OBI:0001180,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001172,,,,,,,,,,,,,,,,half maximal effective concentration (EC50),,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters; Randi Vita,,
http://purl.obolibrary.org/obo/OBI_0200049,Benjamini and Yekutieli false discovery rate correction method,,A data transformation in which the Benjamini and Yekutieli method is applied with the aim of correcting false discovery rate,false,,,http://purl.obolibrary.org/obo/OBI_0200163,,http://purl.obolibrary.org/obo/OBI_0000791,,,,,,,,,,,,,,,,,A data transformation in which the Benjamini and Yekutieli method is applied with the aim of correcting false discovery rate,Helen Parkinson,,,,,"2011-03-31: [PRS]. 
specified input and output of dt which were missing",Benjamini and Yekutieli false discovery rate correction method,,"The expression set was compared univariately between the stroke patients and controls, gene list was generated using False Discovery Rate correction (Benjamini and Yekutieli)",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000175,http://purl.obolibrary.org/obo/OBI_0000662|http://purl.obolibrary.org/obo/OBI_0001442,,,OBI:0200049,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Benjamini and Yekutieli false discovery rate correction method,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra|Helen Parkinson,,
http://purl.obolibrary.org/obo/GO_0008283,cell proliferation,,"The multiplication or reproduction of cells, resulting in the expansion of a cell population.",false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,"The multiplication or reproduction of cells, resulting in the expansion of a cell population.",,,,,,,cell proliferation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0008283,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,cell proliferation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001046,bioreactor,,A device or system that supports a biologically active environment. ALAN SAYS NOT AN INSTRUMENT,false,,,http://purl.obolibrary.org/obo/OBI_0001034,,,,,,,,,,,,,,,,,,,A device or system that supports a biologically active environment. ALAN SAYS NOT AN INSTRUMENT,http://en.wikipedia.org/wiki/Bioreactor,,,,,,bioreactor,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000379|http://purl.obolibrary.org/obo/OBI_0000401,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001046,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,bioreactor,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_1110018,living in endemic area,,a process in which a potential host organism lives in a geographic area in which an infectious agent is present to such a degree of frequency that contact is likely,false,,,http://purl.obolibrary.org/obo/OBI_1110111,,,,,,,,,,,,,,,,,,,a process in which a potential host organism lives in a geographic area in which an infectious agent is present to such a degree of frequency that contact is likely,IEDB,,,,,,living in endemic area,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110018,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,living in endemic area,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001367,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-10 production by T cells,IL-10 release|RNA/DNA detection,An assay of epitope specific interleukin-10 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001209,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-10 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-10 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001367,,,,,,,,,,,,,,,,,,,,,,,,IL-10 release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-10 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000434,adding material objective,,is the specification of an objective to add a material into a target material. The adding is asymmetric in the sense that the target material largely retains its identity,false,,,http://purl.obolibrary.org/obo/OBI_0000686,,,,,,,,,,,,,,,,,,,is the specification of an objective to add a material into a target material. The adding is asymmetric in the sense that the target material largely retains its identity,,,,,,,adding material objective,,creating a mouse infected with LCM virus,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000434,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,adding material objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BP,,
http://purl.obolibrary.org/obo/OBI_0000599,tecmag NMR console,,An NMR console manufactured by tecmac.,false,,,http://purl.obolibrary.org/obo/OBI_0000499,,,,,,,,,,,,,,,,,NMR instrument,,An NMR console manufactured by tecmac.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400246,,,,,,tecmag NMR console,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000599,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,tecmag NMR console,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_1110175,intracellular cytokine staining assay measuring epitope specific interleukin-4 production by T cells,IL-4 release|ICS,An assay of epitope specific interleukin-4 production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001450,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-4 production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-4 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110175,,,,,,,,,,,,,,,,,,,,,,,,IL-4 release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-4 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001792,detection of specific nucleic acids with complementary probes assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells,CCL3/MIP-1a release|RNA/DNA detection,An assay of epitope specific macrophage inflammatory protein-1 alpha production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001333,,,,,,,,,,,,,,,,,,,An assay of epitope specific macrophage inflammatory protein-1 alpha production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001792,,,,,,,,,,,,,,,,,,,,,,,,CCL3/MIP-1a release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000848,polyA RNA extraction,,A RNA extraction process typically involving the use of poly dT oligomers in which the desired output material is polyA RNA.,false,,,http://purl.obolibrary.org/obo/OBI_0666666,,,,,,,,,,,,,,,,,,,A RNA extraction process typically involving the use of poly dT oligomers in which the desired output material is polyA RNA.,UPenn Group,,,,,,polyA RNA extraction,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000848,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,polyA RNA extraction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jie Zheng|Person: Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0001036,specimen fixation function,,a function that allows specific identification of individual speciment from one another.,false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,a function that allows specific identification of individual speciment from one another.,,,,,,,specimen fixation function,,e.g the function of a bar code reader used to read slide bar codes,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001036,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,specimen fixation function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,EAGLE-I,,
http://purl.obolibrary.org/obo/OBI_0001390,biological activity assay measuring epitope specific interferon-beta production by T cells,IFNb release|biological activity,A T cell epitope specific cytokine production assay that detects interferon-beta production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects interferon-beta production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific interferon-beta production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001390,,,,,,,,,,,,,,,,,,,,,,,,IFNb release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific interferon-beta production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0600007,administering substance in vivo,,A process by which a substance is intentionally given to an organism resulting in exposure of the organism to that substance.,false,,,http://purl.obolibrary.org/obo/OBI_0000274,,http://purl.obolibrary.org/obo/OBI_0000434,,,,,,,,,,,,,,,,,A process by which a substance is intentionally given to an organism resulting in exposure of the organism to that substance.,IEDB,,,,,"Update the definition based on the discussion. Details see the tracker:
https://sourceforge.net/p/obi/obi-terms/738/|needs roles such as perturber and perturbee (children of input role). Perturb is too strong. Host might be the name for one role. Others considered: Doner, Donated, Acceptor.|Different routes and means of administration should go as children underneath this|2009-11-10. Tracker: https://sourceforge.net/tracker/?func=detail&aid=2893050&group_id=177891&atid=886178",administering substance in vivo,,"injecting mice with 10 ug morphine intranasally, a patient taking two pills of 1 mg aspirin orally|Balb/c mice received an intracameral or subconjunctival injection of trinitrophenylated spleen cells",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100026,http://purl.obolibrary.org/obo/OBI_0100026,,,OBI:0600007,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,administering substance in vivo,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters|Person:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0200056,moving average,,"A moving average is a data transformation in which center calculations, usually mean calculations, are performed on values within a sliding window across the input data set.",false,,,http://purl.obolibrary.org/obo/OBI_0200170,,,,,,,,,,,,,,,,,,,"A moving average is a data transformation in which center calculations, usually mean calculations, are performed on values within a sliding window across the input data set.",PERSON: Elisabetta Manduchi|PERSON: Helen Parkinson,,,,,,moving average,,The moving average is often used to handle data from tiling arrays.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200056,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,moving average,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Helen Parkinson|Elisabetta Manduchi|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0302889,irradiation,,"irradiation is a process by which a material entity is exposed to radiative energy, which could be ionizing radiation (such as gamma rays or X-rays)  or not such as UV light or microwaves",false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,"irradiation is a process by which a material entity is exposed to radiative energy, which could be ionizing radiation (such as gamma rays or X-rays)  or not such as UV light or microwaves",adapted from wikipedia (http://en.wikipedia.org/wiki/Irradiation),,,,,,irradiation,,PMID: 18563778.Histological and modeling study of skin thermal injury to 2.0 mum laser irradiation.Lasers Surg Med. 2008 Jun 18;40(5):358-370.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0400065,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,OBI:0302889,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,irradiation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/IAO_0000403,three dimensional cartesian spatial coordinate datum,,A cartesion spatial coordinate datum that  uses three values to specify a position within a three dimensional spatial region,false,,,http://purl.obolibrary.org/obo/IAO_0000400,,,,,,,,,,,,,,,,,,,A cartesion spatial coordinate datum that  uses three values to specify a position within a three dimensional spatial region,,,,,,,three dimensional cartesian spatial coordinate datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000403,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,three dimensional cartesian spatial coordinate datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0001225,genetic population background information,,a genetic characteristics information which is a part of genotype information that identifies the population of organisms,false,,,http://purl.obolibrary.org/obo/OBI_0001404,,,,,,,,,,,,,,,,,,,a genetic characteristics information which is a part of genotype information that identifies the population of organisms,Group: OBI group,,,,,"proposed and discussed on San Diego OBI workshop, March 2011",genetic population background information,,"genotype information 'C57BL/6J  Hnf1a+/-' in this case, C57BL/6J is the genetic population background information",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001305,OBI:0001225,http://purl.obolibrary.org/obo/OBI_0001305,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,genetic population background information,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Group: OBI group,,
http://purl.obolibrary.org/obo/GO_0016064,immunoglobulin mediated immune response,,"An immune response mediated by immunoglobulins, whether cell-bound or in solution.",false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,"An immune response mediated by immunoglobulins, whether cell-bound or in solution.",,,,,,,immunoglobulin mediated immune response,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0016064,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,immunoglobulin mediated immune response,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001254,epitope specific interleukin-3 production by T cells,,A process of interleukin-3 production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/OBI_0001193|http://purl.obolibrary.org/obo/GO_0032632,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of interleukin-3 production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific interleukin-3 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001254,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific interleukin-3 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001275,epitope specific interleukin-16 production by T cells,,A process of interleukin-16 production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/OBI_0001193|http://purl.obolibrary.org/obo/GO_0032619,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of interleukin-16 production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific interleukin-16 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001275,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific interleukin-16 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000527,flow high resolution probe,flow HR-probe,Hyphenated analytical techniques combining mass spectrometry and chromatography are well-established laboratory tools. The combination of chromatography and NMR has also made its way into the analytical laboratory. Further developments even combine all three techniques into an LC-NMR/NMR-MS system. The use of solid phase extraction provides an efficient interface between chromatography and NMR with demands for special type of flow probes.,false,,,http://purl.obolibrary.org/obo/OBI_0000480,,,,flow HR-probe,,,,,,,,,,,,,NMR probe,,Hyphenated analytical techniques combining mass spectrometry and chromatography are well-established laboratory tools. The combination of chromatography and NMR has also made its way into the analytical laboratory. Further developments even combine all three techniques into an LC-NMR/NMR-MS system. The use of solid phase extraction provides an efficient interface between chromatography and NMR with demands for special type of flow probes.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400195,,,,,,flow high resolution probe,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000527,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,flow high resolution probe,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0200080,network analysis,network topology analysis,"A data transformation that takes as input data that describes biological networks in terms of the node (a.k.a. vertex) and edge graph elements and their characteristics and generates as output properties of the constituent nodes and edges, the sub-graphs, and the entire network.",false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,network topology analysis,,,,,,,,,,,,,,,"A data transformation that takes as input data that describes biological networks in terms of the node (a.k.a. vertex) and edge graph elements and their characteristics and generates as output properties of the constituent nodes and edges, the sub-graphs, and the entire network.",PERSON: Richard Scheuermann,,,,,,network analysis,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200080,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,network analysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Richard Scheuermann,,
http://purl.obolibrary.org/obo/OBI_1110010,disposition to cause an allergic reaction,allergenic disposition,The role borne by a material entity that is realized when it is recognized by the immune system and results in the occurrence of an allergic disease.,false,,,http://purl.obolibrary.org/obo/BFO_0000016,,,,allergenic disposition,,,,,,,,,,,,,,,The role borne by a material entity that is realized when it is recognized by the immune system and results in the occurrence of an allergic disease.,IEDB,,,,,,disposition to cause an allergic reaction,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110010,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,disposition to cause an allergic reaction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000908,labeled DNA extract,,a labeled specimen that is the output of a labeling process and has grain labeled DNA to be able to detect DNA in future experiments.,false,,,http://purl.obolibrary.org/obo/OBI_0001143,,,,,,,,,,,,,,,,,,,a labeled specimen that is the output of a labeling process and has grain labeled DNA to be able to detect DNA in future experiments.,Group: OBI group,,,,,"Need to find out if we consider labeled nucleotides still nucleotides. It is after consulting with ChEBI group.
Added duirng Mar 1, 2010 dev call",labeled DNA extract,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,http://purl.obolibrary.org/obo/CHEBI_16991,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000908,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,labeled DNA extract,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Group: OBI group,,
http://purl.obolibrary.org/obo/OBI_0001296,cytometric bead array assay measuring epitope specific interleukin-17 production by T cells,IL-17 release|cytometric bead array,An assay of epitope specific interleukin-17 production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001295,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-17 production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific interleukin-17 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001296,,,,,,,,,,,,,,,,,,,,,,,,IL-17 release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific interleukin-17 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/NCBITaxon_8353,Xenopus <genus>,Xenopus,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_32523,,,,Xenopus,,,,,,,,,,,,,,,,,,,,,,Xenopus <genus>,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:8353,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Xenopus <genus>,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0302906,DNA Subtraction,,a material separation process by which repetitive genomic DNA is removed during the construction of cDNA library.,false,,,http://purl.obolibrary.org/obo/OBI_0600014,,http://purl.obolibrary.org/obo/OBI_0000681,,,,,,,,,,,,,,,,,a material separation process by which repetitive genomic DNA is removed during the construction of cDNA library.,OBI-Branch,,,,,,DNA Subtraction,,PMID: 10718422. Identification of genes overexpressed in head and neck squamous cell carcinoma using a combination of complementary DNA subtraction and microarray analysis. Laryngoscope. 2000 Mar;110(3 Pt 1):374-81,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302906,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNA Subtraction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_1110124,assay measuring qualitiative binding of a T cell epitope:MHC:TCR complex,qualitative binding|binding assay,A T cell epitope recognition assay that qualitatively detects MHC:epitope complex binding to TCR.,false,,,http://purl.obolibrary.org/obo/OBI_1110037|http://purl.obolibrary.org/obo/OBI_0001146,,,,,,,,,,,,,,,,,,,A T cell epitope recognition assay that qualitatively detects MHC:epitope complex binding to TCR.,IEDB,,,,,,assay measuring qualitiative binding of a T cell epitope:MHC:TCR complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110124,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|binding assay,,,,,,,,,,,,,,,,,,,,,,assay measuring qualitiative binding of a T cell epitope:MHC:TCR complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/IDO_0000666,human pathogenicity disposition,,A disposition to initiate processes that result in a disorder in a human organism.,false,,,http://purl.obolibrary.org/obo/BFO_0000016,,,,,,,,,,,,,,,,,,,A disposition to initiate processes that result in a disorder in a human organism.,,,,,,,human pathogenicity disposition,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IDO:0000666,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ido.owl,,,,,,,,,,,,,,,,,,,human pathogenicity disposition,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000694,animal feeding,,animal feeding is a process in which animals are provided with food,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,,,animal feeding is a process in which animals are provided with food,branch derived,,,,,"In an investigation, this will typically be part of an animal care process",animal feeding,,giving crickets to a snake.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100026,http://purl.obolibrary.org/obo/OBI_0100026,,,OBI:0000694,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,animal feeding,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000248,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/CLO_0007599,CLO_0007599,,,false,,,http://purl.obolibrary.org/obo/CLO_0000578,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CLO:0007599,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/CHEBI_31991,phenol red,,"3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxyphenyl groups. A pH indicator changing colour from yellow below pH 6.8 to bright pink above pH 8.2, it is commonly used as an indicator in cell cultures and in home swimming pool test kits. It is also used in the (now infrequently performed) phenolsulfonphthalein (PSP) test for estimation of overall blood flow through the kidney.",false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,"3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxyphenyl groups. A pH indicator changing colour from yellow below pH 6.8 to bright pink above pH 8.2, it is commonly used as an indicator in cell cultures and in home swimming pool test kits. It is also used in the (now infrequently performed) phenolsulfonphthalein (PSP) test for estimation of overall blood flow through the kidney.",,,,,,,phenol red,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:31991,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,phenol red,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001666,cell bound MHC direct binding assay measuring binding on rate [kon] of a MHC:ligand complex using fluorescence detection,on rate|cellular MHC/direct/fluorescence|nM^-1s^-1,A cell bound MHC ligand binding on rate (kon) determination assay that uses fluorescence detection to measure direct ligand binding.,false,,,http://purl.obolibrary.org/obo/OBI_0001994|http://purl.obolibrary.org/obo/OBI_0001499,,,,,,,,,,,,,,,,,,,A cell bound MHC ligand binding on rate (kon) determination assay that uses fluorescence detection to measure direct ligand binding.,IEDB,,,,,,cell bound MHC direct binding assay measuring binding on rate [kon] of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001666,,,,,,,,,,,,,,,,,,,,,,,,on rate|cellular MHC/direct/fluorescence|nM^-1s^-1,,,,,,,,,,,,,,,,,,,,,,cell bound MHC direct binding assay measuring binding on rate [kon] of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000531,Bruker CryoProbe,,"The Bruker BioSpin CryoProbe is a high-performance cryogenically cooled probe developed for high-resolution applications. It has improved signal/noise (S/N) ratios obtained by reducing the operating temperature of the coil and the pre-amplifier. As a result, the efficiency of the coil is improved and the noise of the coil and the pre-amplifier are reduced.The dramatic increase in the S/N ratio by a factor of 3-4, as compared to conventional probes, leads to a possible reduction in experiment time of up to 16 or a reduction in required sample concentration by a factor of up to 4. The CryoProbes possess key characteristics for NMR analysis:\n   Significant S/N gains (with moderately salty samples also)\n   Short pulse widths\n   Short ring down times\n   Linear behavior in power response\n   Gradient capability\n   CryoProbes are available as Triple Resonance, Dual, Selective X Detection, MicroImaging, and Quad Nucleus Probes configurations at 400 MHz and higher\n   All high resolution probes have a lock circuit\n   All high resolution probes have Z-gradient.",false,,,http://purl.obolibrary.org/obo/OBI_0000561,,,,,,,,,,,,,,,,,NMR probe,,"The Bruker BioSpin CryoProbe is a high-performance cryogenically cooled probe developed for high-resolution applications. It has improved signal/noise (S/N) ratios obtained by reducing the operating temperature of the coil and the pre-amplifier. As a result, the efficiency of the coil is improved and the noise of the coil and the pre-amplifier are reduced.The dramatic increase in the S/N ratio by a factor of 3-4, as compared to conventional probes, leads to a possible reduction in experiment time of up to 16 or a reduction in required sample concentration by a factor of up to 4. The CryoProbes possess key characteristics for NMR analysis:\n   Significant S/N gains (with moderately salty samples also)\n   Short pulse widths\n   Short ring down times\n   Linear behavior in power response\n   Gradient capability\n   CryoProbes are available as Triple Resonance, Dual, Selective X Detection, MicroImaging, and Quad Nucleus Probes configurations at 400 MHz and higher\n   All high resolution probes have a lock circuit\n   All high resolution probes have Z-gradient.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400191,,,,,,Bruker CryoProbe,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000531,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker CryoProbe,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_1110162,ELISA measuring epitope specific interleukin-17 production by T cells,IL-17 release|ELISA,An assay of epitope specific interleukin-17 production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001295,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-17 production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific interleukin-17 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110162,,,,,,,,,,,,,,,,,,,,,,,,IL-17 release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific interleukin-17 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000447,intra cellular electrophysiology recording,,An intracellular electrophysiology recording is a process where the recording location of the electrode is intracellular,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,http://purl.obolibrary.org/obo/OBI_0000441,,,,,,,,,,,,,,,,,An intracellular electrophysiology recording is a process where the recording location of the electrode is intracellular,PERSON: Frank Gibson,,,,,,intra cellular electrophysiology recording,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000447,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,intra cellular electrophysiology recording,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Frank Gibson,,
http://purl.obolibrary.org/obo/OBI_0001405,cytometric bead array assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells,CCL3/MIP-1a release|cytometric bead array,An assay of epitope specific macrophage inflammatory protein-1 alpha production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001333,,,,,,,,,,,,,,,,,,,An assay of epitope specific macrophage inflammatory protein-1 alpha production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001405,,,,,,,,,,,,,,,,,,,,,,,,CCL3/MIP-1a release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000356,hypothesis generating investigation,,is an investigation in which data is generated and analyzed with the purpose of generating new hypothesis,false,,,http://purl.obolibrary.org/obo/OBI_0000066,,,,,,,,,,,,,,,,,,,is an investigation in which data is generated and analyzed with the purpose of generating new hypothesis,OBI branch derived,,,,,,hypothesis generating investigation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000356,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,hypothesis generating investigation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0002059,assay measuring a binding constant of a T cell epitope:MHC:TCR complex,binding constant|binding assay,A T cell epitope recognition assay that quantitavely characterizes the binding of a TCR with a ligand by determining a binding constant. ,false,,,http://purl.obolibrary.org/obo/OBI_1110037|http://purl.obolibrary.org/obo/OBI_0001025,,,,,,,,,,,,,,,,,,,A T cell epitope recognition assay that quantitavely characterizes the binding of a TCR with a ligand by determining a binding constant. ,IEDB,,,,,,assay measuring a binding constant of a T cell epitope:MHC:TCR complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001144,,,OBI:0002059,,,,,,,,,,,,,,,,,,,,,,,,binding constant|binding assay,,,,,,,,,,,,,,,,,,,,,,assay measuring a binding constant of a T cell epitope:MHC:TCR complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000066,investigation,study,"a planned process that consists of parts: planning, study design execution, documentation and which produce conclusion(s).",false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,"Following OBI call November 2012,26th: it was decided there was no need for adding ""achieves objective of drawing conclusion"" as existing relations were providing equivalent ability. this note closes the issue and validates the class definition to be part of the OBI core
editor = PRS|Could add specific objective specification",,"a planned process that consists of parts: planning, study design execution, documentation and which produce conclusion(s).",OBI branch derived,,,,,,investigation,,"Lung cancer investigation using expression profiling, a stem cell transplant investigation, biobanking is not an investigation, though it may be part of an investigation",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000471|http://purl.obolibrary.org/obo/IAO_0000572|http://purl.obolibrary.org/obo/OBI_0000338,,,,,,,,,,,,,,,,OBI:0000066,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/obi.owl,,,,,,,,,,,,,,,,,,study,investigation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0302900,group randomization,,A group assignment which relies on chance to assign materials to a group of materials in order to avoid bias in experimental set up.,false,,,http://purl.obolibrary.org/obo/OBI_0600015,,,,,,,,,,,,,,,,,,,A group assignment which relies on chance to assign materials to a group of materials in order to avoid bias in experimental set up.,adapted from wikipedia [http://en.wikipedia.org/wiki/Randomization],,,,,,group randomization,,PMID: 18349405. Randomization reveals unexpected acute leukemias in Southwest Oncology Group prostate cancer trial. J Clin Oncol. 2008 Mar 20;26(9):1532-6.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302900,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,group randomization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_1110094,immunization,,The process of an epitope that is part of or derived from an immunogen coming into contact with adaptive immune cells resulting in these cells acquiring immune effector functions specific for the epitope.,false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,The process of an epitope that is part of or derived from an immunogen coming into contact with adaptive immune cells resulting in these cells acquiring immune effector functions specific for the epitope.,IEDB,,,,,,immunization,,Infection with influenza (the immunogen) leading to B cells producing antibodies (the effector function) against surface regions of the HA protein (the epitope).,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110094,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,immunization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000977,paraffin storage,,a storage process with input organism or anatomical entity and paraffin and output material embedded in paraffin for long term storage|need to specify paraffin or wax is one of specified input of the process,false,,,http://purl.obolibrary.org/obo/OBI_0302893,,http://purl.obolibrary.org/obo/OBI_0000806,,,,,,,,,,,,,,,,,a storage process with input organism or anatomical entity and paraffin and output material embedded in paraffin for long term storage,UPenn Group,,,,,,paraffin storage,,"",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000977,,,,,,,,,,,,,,,,,,need to specify paraffin or wax is one of specified input of the process,,,,,,,,,,,,,,,,,,,,,,,,,,,,paraffin storage,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Chris Stoeckert|PERSON: Jie Zheng,,
http://purl.obolibrary.org/obo/OBI_0001656,electron microscopy assay measuring binding of a B cell epitope:antibody complex,qualitative binding|electron microscopy,A B cell epitope qualitative binding to antibody assay that uses an electron microscopy imaging assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001703,,,,,,,,,,,,,,,,,,,A B cell epitope qualitative binding to antibody assay that uses an electron microscopy imaging assay.,IEDB,,,,,,electron microscopy assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001656,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|electron microscopy,,,,,,,,,,,,,,,,,,,,,,electron microscopy assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/BFO_0000034,function,,,false,,,http://purl.obolibrary.org/obo/BFO_0000016,,,,,,,Function,function,,,,,,,,,,,,,,,,,"BFO 2 Reference: In the past, we have distinguished two varieties of function, artifactual function and biological function. These are not asserted subtypes of BFO:function however, since the same function – for example: to pump, to transport – can exist both in artifacts and in biological entities. The asserted subtypes of function that would be needed in order to yield a separate monoheirarchy are not artifactual function, biological function, etc., but rather transporting function, pumping function, etc.",function,"A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])",the function of a heart pacemaker to regulate the beating of a heart through electricity|the function of a hammer to drive in nails|the function of amylase in saliva to break down starch into sugar,,,,,,,,(forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001] ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000034,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/IAO_0000017,model number,,"A model number is an information content entity specifically borne by catalogs, design specifications, advertising materials, inventory systems and similar  that is about manufactured objects of the same class. The model number is an alternative term for the class. The manufactered objects may or may not also bear the model number. Model numbers can be encoded in a variety of other information objects, such as bar codes, numerals, or patterns of dots.",false,,,http://purl.obolibrary.org/obo/IAO_0000028,,,,,,,,,,,,,,,,,,,"A model number is an information content entity specifically borne by catalogs, design specifications, advertising materials, inventory systems and similar  that is about manufactured objects of the same class. The model number is an alternative term for the class. The manufactered objects may or may not also bear the model number. Model numbers can be encoded in a variety of other information objects, such as bar codes, numerals, or patterns of dots.",,,,,,"manufactered items may have more than one model number, sometimes by rebranding, or because companies are sold and the products issued new model numbers",model number,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000017,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,model number,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0001988,assay measuring the dissociation constant [KD] of a MHC:ligand complex,dissociation constant KD|binding assay|nM,A MHC binding constant determination assay measuring equilibrium dissociation constant (KD).,false,,,http://purl.obolibrary.org/obo/OBI_0001553,,,,,,,,,,,,,,,,,,,A MHC binding constant determination assay measuring equilibrium dissociation constant (KD).,IEDB,,,,,,assay measuring the dissociation constant [KD] of a MHC:ligand complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001988,,,,,,,,,,,,,,,,,,,,,,,,dissociation constant KD|binding assay|nM,,,,,,,,,,,,,,,,,,,,,,assay measuring the dissociation constant [KD] of a MHC:ligand complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0400043,flow cell,flow_cell,"Aparatus in the fluidic subsystem where the sheath and sample meet. Can be one of several types; jet-in-air, quartz cuvette, or a hybrid of the two. The sample flows through the center of a fluid column of sheath fluid in the flow cell.",false,,,http://purl.obolibrary.org/obo/OBI_0000967,,,,flow_cell,,,,,,,,,,,,,,,"Aparatus in the fluidic subsystem where the sheath and sample meet. Can be one of several types; jet-in-air, quartz cuvette, or a hybrid of the two. The sample flows through the center of a fluid column of sheath fluid in the flow cell.",http://www.flocyte.com/FRTP/Resources/flow_cytometry_glossary.htm,,,,,,flow cell,,Biofilm Flow Cell,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000370,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400043,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,flow cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:John Quinn,,
http://purl.obolibrary.org/obo/OBI_0001374,injury design,,A study design in which the response of an organism(s) to injury or damage is studied.,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,A study design in which the response of an organism(s) to injury or damage is studied.,MO_726 injury_design,,,,,,injury design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000268,,,,,,,,,,,,,,,,OBI:0001374,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,injury design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000666,background correction data transformation,,A background correction data transformation (sometimes called supervised classification) is a data transformation that has the objective background correction.,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,A background correction data transformation (sometimes called supervised classification) is a data transformation that has the objective background correction.,PERSON: James Malone,,,,,,background correction data transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000666,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,background correction data transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0001479,tissue specimen,,"A specimen that derives from an anatomical part or substance arising from an organism. Examples of tissue specimen include tissue, organ, physiological system, blood, or body location (arm).",false,,,http://purl.obolibrary.org/obo/OBI_0100051,,,,,,,,,,,,,,,,,,,"A specimen that derives from an anatomical part or substance arising from an organism. Examples of tissue specimen include tissue, organ, physiological system, blood, or body location (arm).",MO_954 organism_part,,,,,,tissue specimen,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001479,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,tissue specimen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/GO_0097087,interleukin-17A production,,"The appearance of interleukin-17A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0032620,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-17A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-17A production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0097087,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-17A production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0097088,interleukin-17F production,,"The appearance of interleukin-17F due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0032620,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-17F due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-17F production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0097088,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-17F production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/UBERON_0001638,vein,,Any of the tubular branching vessels that carry blood from the capillaries toward the heart.,false,,,http://purl.obolibrary.org/obo/CARO_0000055,,,,,,,,,,,,,,,,,,,Any of the tubular branching vessels that carry blood from the capillaries toward the heart.,,,,,,,vein,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UBERON:0001638,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uberon.owl,,,,,,,,,,,,,,,,,,,vein,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0019882,antigen processing and presentation,,The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.,false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.,,,,,,,antigen processing and presentation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0019882,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,antigen processing and presentation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001332,DNA methylation profiling by array assay,,An assay in which the methylation state of DNA is determined and is compared between samples using array technology|Philippe Rocca-Serra,false,,,http://purl.obolibrary.org/obo/OBI_0000634,,,,,,,,,,,,,,,,,,,An assay in which the methylation state of DNA is determined and is compared between samples using array technology,EFO_0002759 methylation profiling by array,,,,,,DNA methylation profiling by array assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001332,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNA methylation profiling by array assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: James Malone,,
http://purl.obolibrary.org/obo/OBI_0000909,cloacal specimen,,"A specimen obtained by inserting a swab deeply into the vent of the cloaca of
an organism and vigorously swabbing the wall. The swab should be deeply
stained with fecal material and is then placed in transport medium.",false,,,http://purl.obolibrary.org/obo/OBI_0100051,,,,,,,,,,,,,,,,,,,"A specimen obtained by inserting a swab deeply into the vent of the cloaca of
an organism and vigorously swabbing the wall. The swab should be deeply
stained with fecal material and is then placed in transport medium.",WEB: http://www.wpro.who.int/NR/rdonlyres/EFD2B9A7-2265-4AD0-BC98-97937B4FA83C/0/manualonanimalaidiagnosisandsurveillance.pdf,,,,,,cloacal specimen,,type of sample used in the PCIRN influenza network,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000112,,,,,,,,,,,,OBI:0000909,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cloacal specimen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0000110,pH indicator dye role,pH indicator dye,the role of a dye that is realized when the dye is used in an experiment to measure the pH in a material entity,false,,,http://purl.obolibrary.org/obo/OBI_0000250,,,,pH indicator dye,,,,,,,,,,,,,,,the role of a dye that is realized when the dye is used in an experiment to measure the pH in a material entity,,,,,,,pH indicator dye role,,phenol red in RPMI; pH=4 indicator dye (also carries reference role)|bromophenol blue has a pH indicator dye role,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,pH indicator dye role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jennifer Fostel|Person:Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0001042,pump function,,"a transfer unction where the transfer requires work to move the entity, often against a gradient.",false,,,http://purl.obolibrary.org/obo/OBI_0000383,,,,,,,,,,,,,,,,,,,"a transfer unction where the transfer requires work to move the entity, often against a gradient.",,,,,,,pump function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001042,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,pump function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,EAGLE-I,,
http://purl.obolibrary.org/obo/OBI_0000618,size exclusion column,,A size exclusion column is a chromatography column as used in size exclusion chromatography and which enables the separation of mixtures according to differrences in molecular size.,false,,,http://purl.obolibrary.org/obo/OBI_0000038,,,,,,,,,,,,,,,,,,,A size exclusion column is a chromatography column as used in size exclusion chromatography and which enables the separation of mixtures according to differrences in molecular size.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01100,,,,,,size exclusion column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000618,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,size exclusion column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000742,nucleic acid restriction enzyme digest,,A nucleic acid digest is a material that is the output of a process in which nucleic acids are combined with a restriction enzyme resulting in digested fragments with defined ends based on the enzymes cleavage site,false,,,http://purl.obolibrary.org/obo/OBI_0000047|http://purl.obolibrary.org/obo/CHEBI_33696,,,,,,,,,,,,,,,,,,,A nucleic acid digest is a material that is the output of a process in which nucleic acids are combined with a restriction enzyme resulting in digested fragments with defined ends based on the enzymes cleavage site,,,,,,,nucleic acid restriction enzyme digest,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000742,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,nucleic acid restriction enzyme digest,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Kevin Clancy, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000698,obsolete_DNA ligase,ligase,A DNA ligase is an enzyme that covalently joins two compatible pieces of DNA through the cleavage of an ATP molecule,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,ligase,,,,,,,,,,,,,,,A DNA ligase is an enzyme that covalently joins two compatible pieces of DNA through the cleavage of an ATP molecule,,,,,,5/22 Need to explore if there are GO / other classes exist that capture this. We need it now for cloning experiments|replaced by imported PRO: DNA ligase,obsolete_DNA ligase,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000228,,,,,,,,,,,,,,,,,,OBI:0000698,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_DNA ligase,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Kevin Clancy, Bjoern Peters",,
http://purl.obolibrary.org/obo/CL_0000625,"CD8-positive, alpha-beta T cell",,A T cell expressing an alpha-beta T cell receptor and the CD8 coreceptor.,false,,,http://purl.obolibrary.org/obo/CL_0000789,,,,,,,,,,,,,,,,,,,A T cell expressing an alpha-beta T cell receptor and the CD8 coreceptor.,,,,,,,"CD8-positive, alpha-beta T cell",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CL:0000625,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/cl.owl,,,,,,,,,,,,,,,,,,,"CD8-positive, alpha-beta T cell",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/CL_0000624,"CD4-positive, alpha-beta T cell",,A mature alpha-beta T cell that expresses an alpha-beta T cell receptor and the CD4 coreceptor.,false,,,http://purl.obolibrary.org/obo/CL_0000789,,,,,,,,,,,,,,,,,,,A mature alpha-beta T cell that expresses an alpha-beta T cell receptor and the CD4 coreceptor.,,,,,,,"CD4-positive, alpha-beta T cell",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CL:0000624,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/cl.owl,,,,,,,,,,,,,,,,,,,"CD4-positive, alpha-beta T cell",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001017,single-nucleotide-resolution nucleic acid structure mapping assay using chemical probing,,a single-nucleotide-resolution nucleic acid structure mapping assay which relies on small chemical compounds acting as chemical probes  in order to produce measurement information which one interpreted provide structural information about the RNA species under study.,false,,,http://purl.obolibrary.org/obo/OBI_0000870,,,,,,,,,,,,,,,,,,,a single-nucleotide-resolution nucleic acid structure mapping assay which relies on small chemical compounds acting as chemical probes  in order to produce measurement information which one interpreted provide structural information about the RNA species under study.,RNAO and OBI,,,,,,single-nucleotide-resolution nucleic acid structure mapping assay using chemical probing,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001017,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,single-nucleotide-resolution nucleic acid structure mapping assay using chemical probing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0600057,enzymatic DNA replication,,the use of enzymes to duplicate DNA molecule any process used to make additional copies of a biomaterial,false,,,http://purl.obolibrary.org/obo/OBI_0600058,,,,,,,,,,,,,,,,,,,the use of enzymes to duplicate DNA molecule any process used to make additional copies of a biomaterial,OBI branch derived,,,,,,enzymatic DNA replication,,the use of enzymes to duplicate DNA molecules,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600057,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,enzymatic DNA replication,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Kevin Clancy,,
http://purl.obolibrary.org/obo/OBI_0200040,modular decomposition,,Molecular decomposition is the partition of a network into distinct subgraphs for the purpose of identifying functional clusters. The network data is run through any of several existing algorithms designed to partition a network into distinct subgraphs for the purpose of isolating groups of functionally linked biological elements such as proteins.,false,,,http://purl.obolibrary.org/obo/OBI_0200080,,,,,,,,,,,,,,,,,,,Molecular decomposition is the partition of a network into distinct subgraphs for the purpose of identifying functional clusters. The network data is run through any of several existing algorithms designed to partition a network into distinct subgraphs for the purpose of isolating groups of functionally linked biological elements such as proteins.,editor,,,,,,modular decomposition,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200040,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,modular decomposition,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Tina Hernandez-Boussard,,
http://purl.obolibrary.org/obo/OBI_0001497,biological activity assay measuring epitope specific perforin release by T cells,perforin release|biological activity,A T cell epitope specific cytotoxic T cell degranulation assay that detects perforin release by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_0001269,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytotoxic T cell degranulation assay that detects perforin release by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific perforin release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001497,,,,,,,,,,,,,,,,,,,,,,,,perforin release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific perforin release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/CL_0000182,hepatocyte,,"The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated.",false,,,http://purl.obolibrary.org/obo/CL_0000066,,,,,,,,,,,,,,,,,,,"The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated.",,,,,,,hepatocyte,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CL:0000182,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/cl.owl,,,,,,,,,,,,,,,,,,,hepatocyte,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/IAO_0000301,citation,,a textual entity intended to identify a particular publication,false,,,http://purl.obolibrary.org/obo/IAO_0000300,,,,,,,,,,,,,,,,,,,a textual entity intended to identify a particular publication,,,,,,,citation,,"Verspoor, K., Cohen, KB., Hunter, L. Textual characteristics of traditional and Open Access scientific journals are similar, BMC Bioinformatics 2009, 10:183.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000301,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000310,,,,,,,,,,,,,,,,citation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0400060,ion laser,,An ion laser is a gas laser which uses an ionized gas as its lasing medium.,false,,,http://purl.obolibrary.org/obo/OBI_0400047,,,,,,,,,,,,,,,,,,,An ion laser is a gas laser which uses an ionized gas as its lasing medium.,John Quinn|http://en.wikipedia.org/wiki/Ion_laser,,,,,,ion laser,,2 Watt Lexel 88 Argon Ion laser,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400060,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ion laser,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Daniel Schober,,
http://purl.obolibrary.org/obo/CHEBI_50076,chromium-51,,"A synthetic radioactive isotope of chromium having a half-life of 27.7 days and decaying by electron capture with emission of gamma rays (0.32 MeV); it is used to label red blood cells for measurement of mass or volume, survival time, and sequestration studies, for the diagnosis of gastrointestinal bleeding, and to label platelets to study their survival.",false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,"A synthetic radioactive isotope of chromium having a half-life of 27.7 days and decaying by electron capture with emission of gamma rays (0.32 MeV); it is used to label red blood cells for measurement of mass or volume, survival time, and sequestration studies, for the diagnosis of gastrointestinal bleeding, and to label platelets to study their survival.",,,,,,,chromium-51,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:50076,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,chromium-51,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200062,continuum mass spectrum,,A continuum mass spectrum is a data transformation that contains the full profile of the detected signals for a given ion.,false,,,http://purl.obolibrary.org/obo/OBI_0200085,,http://purl.obolibrary.org/obo/OBI_0200197,,,,,,,,,,,,,,,,,A continuum mass spectrum is a data transformation that contains the full profile of the detected signals for a given ion.,PERSON: Tina Boussard,,,,,,continuum mass spectrum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200062,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,continuum mass spectrum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Tina Hernandez-Boussard|PERSON: James Malone,,
http://purl.obolibrary.org/obo/OBI_0200100,canonical variate analysis,CVA,"canonical variate analysis is a form of discriminant analysis that takes several continuous predictor variables and uses the entire set to predict several criterion variables, each of which is also continuous. CVA simultaneously calculates a linear composite of all x variables and  a linear composite of all y variables. Unlike other multivariate techniques, these weighted composites are derived in pairs. Each linear combination is called a canonical variate and takes the general linear form.",false,,,http://purl.obolibrary.org/obo/OBI_0200106|http://purl.obolibrary.org/obo/OBI_0200171,,http://purl.obolibrary.org/obo/OBI_0200172,,CVA,,,,,,,,,,,,,,,"canonical variate analysis is a form of discriminant analysis that takes several continuous predictor variables and uses the entire set to predict several criterion variables, each of which is also continuous. CVA simultaneously calculates a linear composite of all x variables and  a linear composite of all y variables. Unlike other multivariate techniques, these weighted composites are derived in pairs. Each linear combination is called a canonical variate and takes the general linear form.",WEB: http://en.wikipedia.org/wiki/Canonical_analysis,,,,,,canonical variate analysis,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,canonical variate analysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Tina Hernandez-Boussard,,
http://purl.obolibrary.org/obo/OBI_0001683,chromosome organization assay by fluorescence in-situ hybridization,FISH,is an in-situ hybridization assay that uses fluorescence as means of detection chromosomal integrity,false,,,http://purl.obolibrary.org/obo/OBI_0001686,,,,FISH,,,,,,,,,,,,,,,is an in-situ hybridization assay that uses fluorescence as means of detection chromosomal integrity,,,,,,Changed label from fluorescence in-situ hybridization as per tracker item #788,chromosome organization assay by fluorescence in-situ hybridization,,Duplication of intrachromosomal insertion segments 4q32→q35 confirmed by comparative genomic hybridization and fluorescent in situ hybridization.PMID:22384449,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001683,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,chromosome organization assay by fluorescence in-situ hybridization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra; Marcus Chibucos,,
http://purl.obolibrary.org/obo/OBI_0200169,normalization data transformation,,A normalization data transformation is a data transformation that has objective normalization.,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,A normalization data transformation is a data transformation that has objective normalization.,PERSON: James Malone,,,,,,normalization data transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200169,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,normalization data transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0600014,material component separation,,a material processing in which components of an input material become segregated in space,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,,,,,,,,,,,,,,,,,,a material processing in which components of an input material become segregated in space,IEDB,,,,,,material component separation,,"Using a cell sorter to separate a mixture of T cells into two fractions; one with surface receptor CD8 and the other lacking the receptor, or purification",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000040,http://purl.obolibrary.org/obo/BFO_0000040,,,OBI:0600014,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,material component separation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0200136,edge betweenness calculation,,An edge quality calculation in which the input is a data sets of shortest paths between all pairs of node in the network and the output is the sum of all shortest paths that traverse the specific edge.,false,,,http://purl.obolibrary.org/obo/OBI_0200135,,,,,,,,,,,,,,,,,,,An edge quality calculation in which the input is a data sets of shortest paths between all pairs of node in the network and the output is the sum of all shortest paths that traverse the specific edge.,PERSON: Richard Scheuermann,,,,,,edge betweenness calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200136,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,edge betweenness calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Richard Scheuermann,,
http://purl.obolibrary.org/obo/OBI_0001179,epitope protection from infectious challenge experiment,protection from infectious challenge ,An epitope protection experiment in which the ability of the epitope to protect the host from an infection is assessed. ,false,,,http://purl.obolibrary.org/obo/OBI_0001184,,,,,,,,,,,,,,,,,,,An epitope protection experiment in which the ability of the epitope to protect the host from an infection is assessed. ,,,,,,,epitope protection from infectious challenge experiment,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000712,,,,,,,,,,,,,,,,OBI:0001179,,,,,,,,,,,,,,,,,,,,,,,,protection from infectious challenge ,,,,,,,,,,,,,,,,,,,,,,epitope protection from infectious challenge experiment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001053,electrophoresis system,,A device that moves charged particles through a medium by using an electric field induced by electrodes.,false,,,http://purl.obolibrary.org/obo/OBI_0000932,,,,,,,,,,,,,,,,,,,A device that moves charged particles through a medium by using an electric field induced by electrodes.,http://en.wikipedia.org/wiki/Category:Electrophoresis,,,,,,electrophoresis system,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000372,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001053,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,electrophoresis system,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0000703,Illumina Genome Analyzer II,,is a DNA sequence which is manufactured by Illumina (Solexa) corporation. it support sequencing of single or paired end clone libraries relying on sequencing by synthesis technology,false,,,http://purl.obolibrary.org/obo/OBI_0400103,,,,,,,,,,,,,,,,,,,is a DNA sequence which is manufactured by Illumina (Solexa) corporation. it support sequencing of single or paired end clone libraries relying on sequencing by synthesis technology,Illumina Corporation,,,,,,Illumina Genome Analyzer II,,"PMID: 19336255. RNA-Seq-quantitative measurement of expression through massively parallel RNA-sequencing. Wilhelm BT, Landry JR.Methods. 2009 Jul;48(3):249-57.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000703,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Illumina Genome Analyzer II,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000115,intervention design,,An intervention design is a study design in which a controlled process applied to the subjects (the intervention) serves as the independent variable manipulated by the experimentalist. The treatment (perturbation or intervention) defined can be defined as a combination of values taken by independent variable manipulated by the experimentalists are applied to the recruited subjects assigned (possibly by applying specific methods) to treatment groups. The specificity of intervention design is the fact that independent variables are being manipulated and a response of the biological system is evaluated via response variables as monitored by possibly a series of assays.,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,An intervention design is a study design in which a controlled process applied to the subjects (the intervention) serves as the independent variable manipulated by the experimentalist. The treatment (perturbation or intervention) defined can be defined as a combination of values taken by independent variable manipulated by the experimentalists are applied to the recruited subjects assigned (possibly by applying specific methods) to treatment groups. The specificity of intervention design is the fact that independent variables are being manipulated and a response of the biological system is evaluated via response variables as monitored by possibly a series of assays.,OBI branch derived,,,,,,intervention design,,PMID: 18208636.Br J Nutr. 2008 Jan 22;:1-11.Effect of vitamin D supplementation on bone and vitamin D status among Pakistani immigrants in Denmark: a randomised double-blinded placebo-controlled intervention study.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000115,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,intervention design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philppe Rocca-Serra,,
http://purl.obolibrary.org/obo/PATO_0001985,frozen,,A quality inhering in a bearer by virtue of the bearer's being kept below its freezing point.,false,,,http://purl.obolibrary.org/obo/PATO_0001237,,,,,,,,,,,,,,,,,,,A quality inhering in a bearer by virtue of the bearer's being kept below its freezing point.,,,,,,,frozen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001985,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,frozen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000136,incubator,,"a device in which environmental conditions (light, photoperiod, temperature, humidity, etc.) can be controlled",false,,,http://purl.obolibrary.org/obo/OBI_0001034,,,,,,,,,,,,,,,,,,,"a device in which environmental conditions (light, photoperiod, temperature, humidity, etc.) can be controlled",http://www.medterms.com/script/main/art.asp?articlekey=18426,,,,,,incubator,,"Incubators are used in microbiology for culturing (growing) bacteria and other microorganisms. Incubators in tissue culture rooms are used for culturing stem cells, lymphocytes, skin fibroblasts and other types of cells",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000401,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000136,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,incubator,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Frank Gibson,,
http://purl.obolibrary.org/obo/OBI_0500009,loop design,,A loop experiment design is where labeled extracts are compared in consecutive pairs. synonym: circular design,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,A loop experiment design is where labeled extracts are compared in consecutive pairs. synonym: circular design,MO_912,,,,,,loop design,,PMID: 12933549,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500009,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,loop design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra on behalf of MO,,
http://purl.obolibrary.org/obo/OBI_0000888,nuclear RNA extraction,,A RNA extraction process in which the desired output material is RNA in the nucleus.,false,,,http://purl.obolibrary.org/obo/OBI_0666666,,,,,,,,,,,,,,,,,,,A RNA extraction process in which the desired output material is RNA in the nucleus.,UPenn Group,,,,,,nuclear RNA extraction,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000888,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,nuclear RNA extraction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jie Zheng|Person: Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0000655,blood specimen,,a material entity derived from a portion of blood collected from an organism,false,,,http://purl.obolibrary.org/obo/OBI_0001479,,,,,,,,,,,,,,,,,,,a material entity derived from a portion of blood collected from an organism,Bjoern Peters,,http://purl.obolibrary.org/obo/UBERON_0000178,,,,blood specimen,,blood drawn from a human for glucose assay,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000112,,,,,,,,,,,,OBI:0000655,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0600005,,,blood specimen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001022,gene dosage assay,,"an assay of changes in phenotype due to increased or decreased
dosage of a single allele of a gene.",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,"an assay of changes in phenotype due to increased or decreased
dosage of a single allele of a gene.",David Osumi Sutherland,,,,,,gene dosage assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001022,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,gene dosage assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000572,transfer line,,A combination of devices that are used in connection with a sampling head for transferring components of an applied sample to the analyzing part of a chromatography system.,false,,,http://purl.obolibrary.org/obo/OBI_0000048,,,,,,,,,,,,,,,,,chromatography device,,A combination of devices that are used in connection with a sampling head for transferring components of an applied sample to the analyzing part of a chromatography system.,WEB:<http://www.freepatentsonline.com/5702671.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01235,,,,,,transfer line,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000572,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,transfer line,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001499,fluorescence detection binding assay,,binding assay that uses fluorescence detection as an indicator of binding,false,,,http://purl.obolibrary.org/obo/OBI_0001146,,,,,,,,,,,,,,,,,,,binding assay that uses fluorescence detection as an indicator of binding,IEDB,,,,,,fluorescence detection binding assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001499,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,fluorescence detection binding assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Bjoern Peters, Randi Vita",,
http://purl.obolibrary.org/obo/OBI_0600048,vector mediated amplification,,The process of creating a copy of some biological entity in cell culture,false,,,http://purl.obolibrary.org/obo/OBI_0600064,,,,,,,,,,,,,,,,,,,The process of creating a copy of some biological entity in cell culture,OBI branch derived,,,,,,vector mediated amplification,,E coli expressing the gene for M avium p35 were cultured in order to produce p35.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600048,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,vector mediated amplification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Kevin Clancy,,
http://purl.obolibrary.org/obo/PR_000001004,CD4 molecule,,"A protein that is a translation product of the human CD4 gene or a 1:1 ortholog thereof. CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It is the primary receptor for HIV-1. CD4 has four immunoglobulin-like domains in its extracellular region that share the same structure, but can differ in sequence.",false,,,http://purl.obolibrary.org/obo/PR_000000001,,,,,,,,,,,,,,,,,,,"A protein that is a translation product of the human CD4 gene or a 1:1 ortholog thereof. CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It is the primary receptor for HIV-1. CD4 has four immunoglobulin-like domains in its extracellular region that share the same structure, but can differ in sequence.",,,,,,,CD4 molecule,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PR:000001004,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pr.owl,,,,,,,,,,,,,,,,,,,CD4 molecule,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001365,cellular process design,,"A study design that aims to study the processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A study design that aims to study the processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.",MO_810 cellular_process_design,,,,,,cellular process design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001365,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cellular process design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001932,comparing prediction to measurement,,A planned process in which predicted values for some thing are compared to measured values for that thing.,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,,,A planned process in which predicted values for some thing are compared to measured values for that thing.,,,,,,,comparing prediction to measurement,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001934,,,,OBI:0001932,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,comparing prediction to measurement,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001043,cell transfer function,,is a transfer function that displaces cells from one place to another,false,,,http://purl.obolibrary.org/obo/OBI_0000383,,,,,,,,,,,,,,,,,,,is a transfer function that displaces cells from one place to another,,,,,,,cell transfer function,,A cell harvester has a cell transfer function.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001043,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cell transfer function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,EAGLE-I,,
http://purl.obolibrary.org/obo/OBI_0400121,molecular crosslinker,molecular crosslinker,a device that is able to chemically join two or more molecules.,false,,,http://purl.obolibrary.org/obo/OBI_0001034|http://purl.obolibrary.org/obo/OBI_0001032,,,,molecular crosslinker,,,,,,,,,,,,,,,a device that is able to chemically join two or more molecules.,MO ?? cannot be found in MO,,,,,"AL: if we intend that other ontologies can be used in conjunction with OBI, we shouldn't have such a general term used specifically for chemically joining two or more molecules. I'm sure there are other ""crosslinkers"" that are on a much different scale in engineering etc. I have moved the original label to be an alternative term, and have renamed the main label accordingly.",molecular crosslinker,,Stratalinker,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000401|http://purl.obolibrary.org/obo/OBI_0000367,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400121,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,molecular crosslinker,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Trish Whetzel,,
http://purl.obolibrary.org/obo/IAO_0000321,author list,,part of a document that enumerates the authors of the document,false,,,http://purl.obolibrary.org/obo/IAO_0000314,,,,,,,,,,,,,,,,,,,part of a document that enumerates the authors of the document,,,,,,,author list,,Lawrence Hunter and Kevin Brettonel Cohen,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000302,,,,,,,,,,,,,,,,IAO:0000321,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,author list,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0001702,immunoglobulin binding to epitope,,a process of an immunoglobulin complex binding to a material entity at the immunoglobulin complementarity determining region (CDR). ,false,,,http://purl.obolibrary.org/obo/OBI_1110014|http://purl.obolibrary.org/obo/OBI_0001588,,,,,,,,,,,,,,,,,,,a process of an immunoglobulin complex binding to a material entity at the immunoglobulin complementarity determining region (CDR). ,IEDB,,,,,,immunoglobulin binding to epitope,,Binding of the LA5  antibody to a discontinuous set of amino acid residues on the surface of the D8 protein of Vaccinia virus ,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/GO_0042571,,,,,,,,,,,,,,,OBI:0001702,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,immunoglobulin binding to epitope,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Bjoern Peters, Randi Vita",,
http://purl.obolibrary.org/obo/OBI_0001899,target capture specification,Target Capture,"A plan specification which specifies how the material enrichment procedure will influence the scale, or type of material that will be assayed in the specimen.",false,,,http://purl.obolibrary.org/obo/IAO_0000104,,,,,,,,,,,,,,,,,,,"A plan specification which specifies how the material enrichment procedure will influence the scale, or type of material that will be assayed in the specimen.",NIAID GSCID-BRC metadata working group,,,,,,target capture specification,,"Some examples of target capture are Whole, CloneEnds, Exome, TargetedLocusLoci, RandomSurvey",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0500000,OBI:0001899,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,target capture specification,,,,,,Target Capture,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001565,cell lysate MHC direct binding assay measuring half life of a MHC:ligand complex using radioactivity detection,half life|lysate MHC/direct/radioactivity|min,A cell lysate MHC ligand half life of binding determination assay that uses radioactivity detection to measure direct ligand binding.,false,,,http://purl.obolibrary.org/obo/OBI_0001990|http://purl.obolibrary.org/obo/OBI_0001491,,,,,,,,,,,,,,,,,,,A cell lysate MHC ligand half life of binding determination assay that uses radioactivity detection to measure direct ligand binding.,IEDB,,,,,,cell lysate MHC direct binding assay measuring half life of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001565,,,,,,,,,,,,,,,,,,,,,,,,half life|lysate MHC/direct/radioactivity|min,,,,,,,,,,,,,,,,,,,,,,cell lysate MHC direct binding assay measuring half life of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0600055,"DNA cleavage, restriction analysis",restriction enzyme assay,"the use of enzymes to cut DNA molecules, the study of DNA through cleavage, mapping, and analysis of the fragments",false,,,http://purl.obolibrary.org/obo/OBI_0000231,,,,restriction enzyme assay,,,,,,,,,,,,,,,"the use of enzymes to cut DNA molecules, the study of DNA through cleavage, mapping, and analysis of the fragments","the use of the restriction enzymes SalPI and PstI to cleave DNA into fragments, assay made up of components",,,,,,"DNA cleavage, restriction analysis",,"the use of the restriction enzymes SalPI and PstI to cleave DNA into fragments, assay made up of components",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_33697,,,,OBI:0600055,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"DNA cleavage, restriction analysis",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Kevin Clancy,,
http://purl.obolibrary.org/obo/OBI_0000894,protein extract,,"a protein extract is the output of an extraction process from tissues or cell cultures resulting in a solution of cellular and/or organellar proteins in buffer solution used to prevent degradation,",false,,,http://purl.obolibrary.org/obo/OBI_0000423,,,,,,,,,,,,,,,,,,,"a protein extract is the output of an extraction process from tissues or cell cultures resulting in a solution of cellular and/or organellar proteins in buffer solution used to prevent degradation,",OBI & wikipedia,,,,,,protein extract,,"PMID: 20032479. A bovine whey protein extract stimulates human neutrophils to generate bioactive IL-1Ra through a NF-kappaB- and MAPK-dependent mechanism. Rusu D, Drouin R, Pouliot Y, Gauthier S, Poubelle PE.
J Nutr. 2010 Feb;140(2):382-91. Epub 2009 Dec 23.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/PR_000000001,,,,,,,,,,,,,,,,OBI:0000894,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0302884,,,protein extract,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001024,RNASE U2 structure mapping assay,single nucleotide resolution mapping assay using RNAse U2,a single-nucleotide-resolution ribonucleic acid structure mapping assay which uses RNAase U2 as reagent and enzymatic probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,false,,,http://purl.obolibrary.org/obo/OBI_0001014,,http://purl.obolibrary.org/obo/OBI_0000441,,single nucleotide resolution mapping assay using RNAse U2,,,,,,,,,,,,,,,a single-nucleotide-resolution ribonucleic acid structure mapping assay which uses RNAase U2 as reagent and enzymatic probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,RNA ontology,,,,,,RNASE U2 structure mapping assay,,PMID:409999,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_33697,,,,OBI:0001024,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,RNASE U2 structure mapping assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000376,synthesizing function,,A synthesizing function is a function to assemble new output materials from distinct input materials.  The output materials typically consist of chemically distinct monomeric objects or object aggregate polymers.,false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,A synthesizing function is a function to assemble new output materials from distinct input materials.  The output materials typically consist of chemically distinct monomeric objects or object aggregate polymers.,,,,,,,synthesizing function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000376,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,synthesizing function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bill Bug|Daniel Schober|Frank Gibson|Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0000818,calibration,,"A planned process with the objective to establish the relationship between data produced by a measurement device and physical qualities. This is done by using the measurement device under defined conditions, and either tuning it to adjust the measured output, or record the output and use it as a reference in future measurements.",false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,,,"A planned process with the objective to establish the relationship between data produced by a measurement device and physical qualities. This is done by using the measurement device under defined conditions, and either tuning it to adjust the measured output, or record the output and use it as a reference in future measurements.",WEB:http://en.wikipedia.org/wiki/calibration,,,,,,calibration,,the process of using pH buffer adjust a pH meter,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000832,,,OBI:0000818,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,calibration,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP: OBI Philly workshop,,
http://purl.obolibrary.org/obo/OBI_0000717,HeliScope Single Molecule Sequencer,,is a DNA sequencer manufacturer by Helicos Corporation to carry out Single Molecule sequencing using reversible termination chemistry,false,,,http://purl.obolibrary.org/obo/OBI_0400103,,,,,,,,,,,,,,,,,,,is a DNA sequencer manufacturer by Helicos Corporation to carry out Single Molecule sequencing using reversible termination chemistry,,,,,,,HeliScope Single Molecule Sequencer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000717,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,HeliScope Single Molecule Sequencer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0600056,protease cleavage,,protease cleavage is an enzymatic cleavage which relies on enzyme with protease activity to act on proteins and produce polypeptides (protein fragments).,false,,,http://purl.obolibrary.org/obo/OBI_0000231,,,,,,,,,,,,,,,,,,,protease cleavage is an enzymatic cleavage which relies on enzyme with protease activity to act on proteins and produce polypeptides (protein fragments).,OBI branch derived,,,,,enzymatic digestion,protease cleavage,,the use of trypsin to cleave pepsin into peptide fragments,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_16670,,,OBI:0600056,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,protease cleavage,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0200103,multiple linear regression analysis,,"multiple linear regression is a regression method that models the relationship between a dependent variable Y, independent variables Xi, i = 1, ..., p, and a random term epsilon. The model can be written as
    Y = \beta_0 + \beta_1 X_1 + \beta_2 X_2 + \cdots +\beta_p X_p + \varepsilon
where \beta_0 =  0 is the intercept (""constant"" term), the \beta_i s  are the respective parameters of independent variables, and p is the number of parameters to be estimated in the linear regression.",false,,,http://purl.obolibrary.org/obo/OBI_0200102,,,,,,,,,,,,,,,,,,,"multiple linear regression is a regression method that models the relationship between a dependent variable Y, independent variables Xi, i = 1, ..., p, and a random term epsilon. The model can be written as
    Y = \beta_0 + \beta_1 X_1 + \beta_2 X_2 + \cdots +\beta_p X_p + \varepsilon
where \beta_0 =  0 is the intercept (""constant"" term), the \beta_i s  are the respective parameters of independent variables, and p is the number of parameters to be estimated in the linear regression.",WEB:http://en.wikipedia.org/wiki/Linear_regression,,,,,,multiple linear regression analysis,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200103,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,multiple linear regression analysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Tina Hernandez-Boussard,,
http://purl.obolibrary.org/obo/OBI_0001072,cryostat,,"A device consisting of a vessel, similar in construction to a vacuum flask, that is used to maintain cold cryogenic temperatures. FIX THIS DEFINITION",false,,,http://purl.obolibrary.org/obo/OBI_0000967|http://purl.obolibrary.org/obo/OBI_0001034,,,,,,,,,,,,,,,,,,,"A device consisting of a vessel, similar in construction to a vacuum flask, that is used to maintain cold cryogenic temperatures. FIX THIS DEFINITION",http://en.wikipedia.org/wiki/Cryostat,,,,,,cryostat,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000370|http://purl.obolibrary.org/obo/OBI_0000379|http://purl.obolibrary.org/obo/OBI_0000387,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001072,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cryostat,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/BFO_0000142,one-dimensional continuant fiat boundary,,,false,,,http://purl.obolibrary.org/obo/BFO_0000140,,,,,,,OneDimensionalContinuantFiatBoundary,1d-cf-boundary,,,,,,,,,,,,,,,,,,one-dimensional continuant fiat boundary,a one-dimensional continuant fiat boundary is a continuous fiat line whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [032-001]),the line separating the outer surface of the mucosa of the lower lip from the outer surface of the skin of the chin.|all lines of latitude and longitude|The Equator|the median sulcus of your tongue|all geopolitical boundaries,,,,,,,,(iff (OneDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (OneDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [032-001] ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000142,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,one-dimensional continuant fiat boundary,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000690,immunoprecipitation,,is a process which realizes a material separation objective by relying on antibodies to specifically binding to material entity,false,,,http://purl.obolibrary.org/obo/OBI_0600014,,http://purl.obolibrary.org/obo/OBI_0000639,,,,,,,,,,,,,,,,,is a process which realizes a material separation objective by relying on antibodies to specifically binding to material entity,OBI plan and planned process branch,,,,,,immunoprecipitation,,"PMID: 19419533. Arabidopsis RNA immunoprecipitation. Terzi LC, Simpson GG. Plant J. 2009 Jul;59(1):163-8.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/GO_0042571,,,,OBI:0000690,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,immunoprecipitation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0302895,electrocution,,electrocution is process by which electric current is applied to a material with quality alive and result the termination of life process.,false,,,http://purl.obolibrary.org/obo/OBI_0000919,,,,,,,,,,,,,,,,,,,electrocution is process by which electric current is applied to a material with quality alive and result the termination of life process.,OBI branch,,,,,,electrocution,,PMID: 9587208. Electrocution of horses and cattle. Vet Rec. 1998 Apr 4;142(14):376.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0400142,,,,,,,,,,,,,,,OBI:0302895,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,electrocution,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000094,material processing,material transformation,A planned process which results in physical changes in a specified input material,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,material transformation,,,,,,,,,,,,,,,A planned process which results in physical changes in a specified input material,OBI branch derived,,,,,,material processing,,"A cell lysis, production of a cloning vector, creating a buffer.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000040,http://purl.obolibrary.org/obo/OBI_0000047,,,OBI:0000094,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,material processing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters|PERSON: Melanie Courtot|PERSON: Jennifer Fostel|PERSON: Frank Gibson|PERSON: Philippe Rocca Serra,,
http://purl.obolibrary.org/obo/BFO_0000027,object aggregate,,,false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,ObjectAggregate,object-aggregate,,,,,,,,,,,,"ISBN:978-3-938793-98-5pp124-158#Thomas Bittner and Barry Smith, 'A Theory of Granular Partitions', in K. Munn and B. Smith (eds.), Applied Ontology: An Introduction, Frankfurt/Lancaster: ontos, 2008, 125-158.",,,,,"An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects |BFO 2 Reference: object aggregates may gain and lose parts while remaining numerically identical (one and the same individual) over time. This holds both for aggregates whose membership is determined naturally (the aggregate of cells in your body) and aggregates determined by fiat (a baseball team, a congressional committee).",object aggregate,b is an object aggregate means: b is a material entity consisting exactly of a plurality of objects as member_parts at all times at which b exists. (axiom label in BFO2 Reference: [025-004]),"the nitrogen atoms in the atmosphere|the aggregate of bearings in a constant velocity axle joint|a collection of cells in a blood biobank.|the restaurants in Palo Alto|defined via attributive delimitations such as: the patients in this hospital|a symphony orchestra|the aggregate of blood cells in your body|defined through physical attachment: the aggregate of atoms in a lump of granite|defined through physical containment: the aggregate of molecules of carbon dioxide in a sealed container|an organization is an aggregate whose member parts have roles of specific types (for example in a jazz band, a chess club, a football team)|defined by fiat: the aggregate of members of an organization|your collection of Meissen ceramic plates.|a swarm of bees is an aggregate of members who are linked together through natural bonds",,,,,,,,(forall (x) (if (ObjectAggregate x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y z) (and (Object y) (Object z) (memberPartOfAt y x t) (memberPartOfAt z x t) (not (= y z)))))) (not (exists (w t_1) (and (memberPartOfAt w x t_1) (not (Object w)))))))) // axiom label in BFO2 CLIF: [025-004] ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000027,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,object aggregate,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000489,nitrogen phosphorous detector,,"The nitrogen phosphorus detector (NPD) (sometimes called the thermionic detector) is a very sensitive, specific detector the design of which, is based on the FID. Physically the sensor appears to be very similar to the FID but, in fact, operates on an entirely different principle. The nitrogen phosphorous detector (sometimes called the thermionic detector) is a very sensitive but specific detector that responds almost exclusively to nitrogen and phosphorous compounds. It is based on the flame ionization detector but differs in that it contains a rubidium or cesium silicate (glass) bead situated in a heater coil, a little distance from the hydrogen flame. If the detector is to respond to both nitrogen and phosphorous then the hydrogen flow should be minimal so that the gas does not ignite at the jet. If the detector is to respond to phosphorous only, a large flow of hydrogen is used which is burnt at the jet. The heated bead emits electrons by thermionic emission. These electrons are collected under a potential of a few volts by an appropriately placed anode, and provides a background current. When a solute containing nitrogen or phosphorous is eluted from the column, the partially combusted nitrogen and phosphorous materials are adsorbed on the surface of the bead. The adsorbed material reduces the work function of the surface and, as consequence, the emission of electrons is increased which raises the current collected at the electrode. The sensitivity of the detector to phosphorous is about 10-12 gram per ml and for nitrogen about 10-11 gram per ml at a signal to nose ratio of 2. The alkali bead as a finite life and needs regular replacement.",false,,,http://purl.obolibrary.org/obo/OBI_0000637,,,,,,,,,,,,,,,,,,,"The nitrogen phosphorus detector (NPD) (sometimes called the thermionic detector) is a very sensitive, specific detector the design of which, is based on the FID. Physically the sensor appears to be very similar to the FID but, in fact, operates on an entirely different principle. The nitrogen phosphorous detector (sometimes called the thermionic detector) is a very sensitive but specific detector that responds almost exclusively to nitrogen and phosphorous compounds. It is based on the flame ionization detector but differs in that it contains a rubidium or cesium silicate (glass) bead situated in a heater coil, a little distance from the hydrogen flame. If the detector is to respond to both nitrogen and phosphorous then the hydrogen flow should be minimal so that the gas does not ignite at the jet. If the detector is to respond to phosphorous only, a large flow of hydrogen is used which is burnt at the jet. The heated bead emits electrons by thermionic emission. These electrons are collected under a potential of a few volts by an appropriately placed anode, and provides a background current. When a solute containing nitrogen or phosphorous is eluted from the column, the partially combusted nitrogen and phosphorous materials are adsorbed on the surface of the bead. The adsorbed material reduces the work function of the surface and, as consequence, the emission of electrons is increased which raises the current collected at the electrode. The sensitivity of the detector to phosphorous is about 10-12 gram per ml and for nitrogen about 10-11 gram per ml at a signal to nose ratio of 2. The alkali bead as a finite life and needs regular replacement.",WEB:<http://www.chromatography-online.org/topics/nitrogen/phosphorus/detector.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01089,,,,,,nitrogen phosphorous detector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000489,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,nitrogen phosphorous detector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0600002,tumor grading,grading of tumor,"Determination of the grade (severity/stage) of a tumor sample, used in cancer biology to describe abnormalities/qualities of tumor cells or tissues. Values can be described by terms from NCI Thesaurus.",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,http://purl.obolibrary.org/obo/OBI_0000441,,grading of tumor,,,,,,,,,,,,,,,"Determination of the grade (severity/stage) of a tumor sample, used in cancer biology to describe abnormalities/qualities of tumor cells or tissues. Values can be described by terms from NCI Thesaurus.",OBI branch derived; submitted by MO,,,,,,tumor grading,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100051,,,,OBI:0600002,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,tumor grading,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Compiled by Helen Parkinson for Transcriptomics thanks to Adam Witney,,
http://purl.obolibrary.org/obo/OBI_0000563,fluorescene detector,,"A single wavelength detector, where the excitation light wavelength is normally a mercury lamp generated high intensity UV light at 253.7 nm. Many substances that fluoresce will be excited by light of this wavelength and hence be detected.",false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,"A single wavelength detector, where the excitation light wavelength is normally a mercury lamp generated high intensity UV light at 253.7 nm. Many substances that fluoresce will be excited by light of this wavelength and hence be detected.",WEB:<http://www.chromatography-online.org/HPLC-Detectors/Fluorescence/Single-Wavelength-Excitation/rs57.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01080,,,,,,fluorescene detector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000563,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,fluorescene detector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001322,ELISPOT assay measuring epitope specific granzyme B release by T cells,granzyme B release|ELISPOT,A T cell epitope specific granzyme B release assay that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001436,,,,,,,,,,,,,,,,,,,A T cell epitope specific granzyme B release assay that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific granzyme B release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001322,,,,,,,,,,,,,,,,,,,,,,,,granzyme B release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific granzyme B release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/BFO_0000026,one-dimensional spatial region,,,false,,,http://purl.obolibrary.org/obo/BFO_0000006,,,,,,,OneDimensionalSpatialRegion,1d-s-region,,,,,,,,,,,,,,,,,,one-dimensional spatial region,A one-dimensional spatial region is a line or aggregate of lines stretching from one point in space to another. (axiom label in BFO2 Reference: [038-001]),an edge of a cube-shaped portion of space.,,,,,,,,(forall (x) (if (OneDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [038-001] ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000026,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,one-dimensional spatial region,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/UBERON_0000178,blood,,A fluid that is composed of blood plasma and erythrocytes.,false,,,http://purl.obolibrary.org/obo/CARO_0000004,,,,,,,,,,,,,,,,,,,A fluid that is composed of blood plasma and erythrocytes.,,,,,,,blood,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UBERON:0000178,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uberon.owl,,,,,,,,,,,,,,,,,,,blood,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000430,plasmid,,"plasmid = DNA and has_quality circular and has_function
(is_realized_as some gene expression) GO:0010467",false,,,http://purl.obolibrary.org/obo/CHEBI_4705,,,,,,,,,,,,,,,,,,,"plasmid = DNA and has_quality circular and has_function
(is_realized_as some gene expression) GO:0010467",group:OBI,,,,,,plasmid,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000430,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,plasmid,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0002015,transcription profiling by MPSS assay,expression MPSS,An assay in which the transcriptome of a biological sample is analysed using Massive Parallel Signature Sequencing (MPSS).,false,,,http://purl.obolibrary.org/obo/OBI_0000424,,http://purl.obolibrary.org/obo/OBI_0001331,,expression MPSS,,,,,,,,,,,,,,,An assay in which the transcriptome of a biological sample is analysed using Massive Parallel Signature Sequencing (MPSS).,http://en.wikipedia.org/wiki/Massively_parallel_signature_sequencing,,,,,,transcription profiling by MPSS assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000711|http://purl.obolibrary.org/obo/OBI_0000626,http://purl.obolibrary.org/obo/OBI_1000207,,,,,,,,,,,,,,,OBI:0002015,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,transcription profiling by MPSS assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Beta Cell Biology Consoritum,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000154,role of Institutional Review Board,Internal Review Board,the role of a organization that is realized by members reviewing study designs for their agreement with regulations,false,,,http://purl.obolibrary.org/obo/OBI_0000014,,,,Internal Review Board,,,,,,,,,,,,,"CDISC definition:  institutional review board; independent ethics committee (IEC). An independent body (a review board or a committee, institutional, regional, national, or supranational) constituted of medical/scientific professionals and non-scientific members, whose responsibility it is to ensure the protection of the rights, safety and well-being of human subjects involved in a trial.",,the role of a organization that is realized by members reviewing study designs for their agreement with regulations,"OBI, CDISC",,,,,,role of Institutional Review Board,,"An institutional review board/independent ethics committee (IRB/IEC) (also known as ethical review board) is a group that has been formally designated to approve, monitor, and review biomedical and behavioral research involving humans with the alleged aim to protect the rights and welfare of the subjects.  Wikipedia March 2008|Animal protocol review board",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000154,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,role of Institutional Review Board,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Jennifer Fostel|Person:Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0200152,polynomial degree,,"The polynomial degree is a feature of a polynomial function defined as the highest power of the polynomial's terms, where the terms of a polynomial are the individual summands with the coefficients omitted.",false,,,http://purl.obolibrary.org/obo/OBI_0200140,,,,,,,,,,,,,,,,,,,"The polynomial degree is a feature of a polynomial function defined as the highest power of the polynomial's terms, where the terms of a polynomial are the individual summands with the coefficients omitted.",PERSON: Elisabetta Manduchi,,,,,,polynomial degree,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200152,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,polynomial degree,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0001509,Edman degradation assay measuring MHC ligand processing and presentation,ligand presentation|Edman degradation,A MHC ligand processing and presentation assay that uses Edman degradation to identify the eluted ligands,false,,,http://purl.obolibrary.org/obo/OBI_1110125,,,,,,,,,,,,,,,,,,,A MHC ligand processing and presentation assay that uses Edman degradation to identify the eluted ligands,IEDB,,,,,,Edman degradation assay measuring MHC ligand processing and presentation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001509,,,,,,,,,,,,,,,,,,,,,,,,ligand presentation|Edman degradation,,,,,,,,,,,,,,,,,,,,,,Edman degradation assay measuring MHC ligand processing and presentation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001507,in vivo assay measuring T cell epitope specific treatment of disease,decreased disease|in vivo assay,An efficacy of T cell epitope intervention experiment that detects a decrease in disease.,false,,,http://purl.obolibrary.org/obo/OBI_0001484,,,,,,,,,,,,,,,,,,,An efficacy of T cell epitope intervention experiment that detects a decrease in disease.,IEDB,,,,,,in vivo assay measuring T cell epitope specific treatment of disease,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001507,,,,,,,,,,,,,,,,,,,,,,,,decreased disease|in vivo assay,,,,,,,,,,,,,,,,,,,,,,in vivo assay measuring T cell epitope specific treatment of disease,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001630,analytical chromatography,,An analyte assay that uses a biomaterial's preferential affinity for either the mobile phase or the stationary phase to separate it from other materials and thereby detect its presence in an input material.,false,,,http://purl.obolibrary.org/obo/OBI_0000443,,,,,,,,,,,,,,,,,,,An analyte assay that uses a biomaterial's preferential affinity for either the mobile phase or the stationary phase to separate it from other materials and thereby detect its presence in an input material.,IEDB,,,,,,analytical chromatography,,"Detection of the presence of blood group A specific antibodies by passing a serum sample through an affinity column containing blood group A carbohydrate, and quantifying the protein content eluted from the column.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001630,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,analytical chromatography,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001023,Fe-BABE RNA structure mapping assay,single nucleotide resolution mapping assay using Fe-BABE probe,a single-nucleotide-resolution ribonucleic acid structure mapping assay which uses Fe-BABE as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,false,,,http://purl.obolibrary.org/obo/OBI_0001017,,http://purl.obolibrary.org/obo/OBI_0000441,,single nucleotide resolution mapping assay using Fe-BABE probe,,,,,,,,,,,,,,,a single-nucleotide-resolution ribonucleic acid structure mapping assay which uses Fe-BABE as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,RNA ontology,,,,,,Fe-BABE RNA structure mapping assay,,PMID: 7862644,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_33697,,,,OBI:0001023,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Fe-BABE RNA structure mapping assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000712,pathogen challenge,,A pathogen challenge is the administration of a live pathogenic organism to a host,false,,,http://purl.obolibrary.org/obo/OBI_0600007,,,,,,,,,,,,,,,,,,,A pathogen challenge is the administration of a live pathogenic organism to a host,,,,,,,pathogen challenge,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000712,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,pathogen challenge,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000725,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001378,ELISA measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells,CCL4/MIP-1b release|ELISA,An assay of epitope specific chemokine (C-C motif) ligand 4 production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001345,,,,,,,,,,,,,,,,,,,An assay of epitope specific chemokine (C-C motif) ligand 4 production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001378,,,,,,,,,,,,,,,,,,,,,,,,CCL4/MIP-1b release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001112,autoclave,,"A device that is used to sterilize equipment and supplies by subjecting them to high pressure steam at 121 C or more, typically for 15 to 20 minutes depending on the size of the load and the contents.",false,,,http://purl.obolibrary.org/obo/OBI_0001034,,,,,,,,,,,,,,,,,,,"A device that is used to sterilize equipment and supplies by subjecting them to high pressure steam at 121 C or more, typically for 15 to 20 minutes depending on the size of the load and the contents.","J. Black, Microbiology, Prentice Hall (1993) pg. 334; http://en.wikipedia.org/wiki/Autoclave",,,,,,autoclave,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000379|http://purl.obolibrary.org/obo/OBI_0000371|http://purl.obolibrary.org/obo/OBI_0000946,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001112,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,autoclave,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0500028,exclusion criterion,,"an exclusion criterion (rule) is_a *eligibility criterion*  which defines and states a condition which, if met, makes an entity unsuitable for a given task or participation in a given process. For instance, in a study protocol, exclusion criteria indicate the conditions that prospective subjects SHOULD NOT meet to be eligible for participation in a study",false,,,http://purl.obolibrary.org/obo/OBI_0500026,,,,,,,,,,,,,,,,,,,"an exclusion criterion (rule) is_a *eligibility criterion*  which defines and states a condition which, if met, makes an entity unsuitable for a given task or participation in a given process. For instance, in a study protocol, exclusion criteria indicate the conditions that prospective subjects SHOULD NOT meet to be eligible for participation in a study",Adapted from Clinical Research Glossary Version 4.0 CDICS glossary group,,,,,,exclusion criterion,,PMID: 17600285-Exclusion criteria included the use of any topical ophthalmic or topical oral medication and/or history of ocular or oral surgery within the past six months.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500028,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,exclusion criterion,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/IAO_0000132,lot number,batch number,"A lot number is an information content entity which is an identical sequence of character borne by part of manufactured product or its packaging for each instances of a product class in a discrete batch of an item. Lot numbers are usually assigned to each separate production run of an item. Manufacturing as a lot might be due to a variety of reasons, for example,  a single process during which many individuals are made from the same portion of source material. Lot numbers can be encoded in a pattern  of other information objects, such as bar codes, numerals, or patterns of dots.",false,,,http://purl.obolibrary.org/obo/IAO_0000028,,,,batch number,,,,,,,,,,,,,,,"A lot number is an information content entity which is an identical sequence of character borne by part of manufactured product or its packaging for each instances of a product class in a discrete batch of an item. Lot numbers are usually assigned to each separate production run of an item. Manufacturing as a lot might be due to a variety of reasons, for example,  a single process during which many individuals are made from the same portion of source material. Lot numbers can be encoded in a pattern  of other information objects, such as bar codes, numerals, or patterns of dots.",,,,,,,lot number,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000132,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,lot number,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP: IAO,,
http://purl.obolibrary.org/obo/OBI_0000602,column frit,,"A part of the column content that separates column packing compartments. In radial columns the packing is supported between two cylindrical frits and the gap between represents the bed height or column length. The outer frit is the column inlet and consequently the sample initially has a large area of stationary phase with which to interact. Frits are porous metal products to prevent unwanted particles from entering the chromatography system. These particles may come from the sample, the solvent or debris generated by the chromatography system itself. Such particles entering the system may lead to clogging of capillaries, interference with the chromatography by changing chromatographic parameters or disturbance of the detector function. Characteristics of a frit, besides the diameter and the thickness, is the porosity (pore distribution, density).",false,,,http://purl.obolibrary.org/obo/OBI_0000048,,,,,,,,,,,,,,,,,chromatography device,,"A part of the column content that separates column packing compartments. In radial columns the packing is supported between two cylindrical frits and the gap between represents the bed height or column length. The outer frit is the column inlet and consequently the sample initially has a large area of stationary phase with which to interact. Frits are porous metal products to prevent unwanted particles from entering the chromatography system. These particles may come from the sample, the solvent or debris generated by the chromatography system itself. Such particles entering the system may lead to clogging of capillaries, interference with the chromatography by changing chromatographic parameters or disturbance of the detector function. Characteristics of a frit, besides the diameter and the thickness, is the porosity (pore distribution, density).",WEB:<http://www.chromatography-online.org/topics/radial/columns.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01070,,,,,,column frit,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000602,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,column frit,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000673,statistical hypothesis test,,A statistical hypothesis test data transformation is a data transformation that has objective statistical hypothesis test.,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,A statistical hypothesis test data transformation is a data transformation that has objective statistical hypothesis test.,PERSON: James Malone,,,,,,statistical hypothesis test,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000673,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,statistical hypothesis test,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0000096,protocol testing objective,,Protocol_testing_objective is a methodology_testing_objective role describing a study designed to examine the effects of using different protocols.,false,,,http://purl.obolibrary.org/obo/OBI_0000208,,,,,,,,,,,,,,,,,,,Protocol_testing_objective is a methodology_testing_objective role describing a study designed to examine the effects of using different protocols.,,,,,,,protocol testing objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000096,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,protocol testing objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel,,
http://purl.obolibrary.org/obo/NCBITaxon_33213,Bilateria,,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_33154,,,,,,,,,,,,,,,,,,,,,,,,,,Bilateria,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:33213,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Bilateria,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200128,directed network graph construction,,A network graph construction in which an input data set describing objects and directional relationships between objects is transformed into and output representation of these objects as nodes and the directional relationships as directed edges of a network graph.,false,,,http://purl.obolibrary.org/obo/OBI_0200126,,,,,,,,,,,,,,,,,,,A network graph construction in which an input data set describing objects and directional relationships between objects is transformed into and output representation of these objects as nodes and the directional relationships as directed edges of a network graph.,PERSON: Richard Scheuermann,,,,,,directed network graph construction,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200128,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,directed network graph construction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Richard Scheuermann,,
http://purl.obolibrary.org/obo/OBI_0001297,cytometric bead array assay measuring epitope specific interleukin-10 production by T cells,IL-10 release|cytometric bead array,An assay of epitope specific interleukin-10 production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001209,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-10 production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific interleukin-10 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001297,,,,,,,,,,,,,,,,,,,,,,,,IL-10 release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific interleukin-10 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000867,establishing cancer cell line,,is a planned process in which the objective is to generate a cell line from a natural population of cancer cells which are already immortal|Helen Parkinson,false,,,http://purl.obolibrary.org/obo/OBI_0001867,,,,,,,,,,,,,,,,,,,is a planned process in which the objective is to generate a cell line from a natural population of cancer cells which are already immortal,"",,,,,,establishing cancer cell line,,Establishment of HeLa immortal cell line,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001906,,,OBI:0000867,,,,,,,,,,,,,,,,,,Helen Parkinson,,,,,,,,,,,,,,,,,,,,,,,,,,,,establishing cancer cell line,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200101,linear discriminant functional analysis,,"Linear discriminant functional analysis (LDFA) is a multivariate technique used in special applications where there are several intact groups (random assignment may be impossible) and they have been measured on several independent measures. Thus, you will want to describe how these groups differ on the basis of these measures. In this case, classification and prediction is the main objective.",false,,,http://purl.obolibrary.org/obo/OBI_0200106|http://purl.obolibrary.org/obo/OBI_0200175|http://purl.obolibrary.org/obo/OBI_0000663,,,,,,,,,,,,,,,,,,,"Linear discriminant functional analysis (LDFA) is a multivariate technique used in special applications where there are several intact groups (random assignment may be impossible) and they have been measured on several independent measures. Thus, you will want to describe how these groups differ on the basis of these measures. In this case, classification and prediction is the main objective.",PERSON: Tina Hernandez-Boussard,,,,,,linear discriminant functional analysis,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000648,,,OBI:0200101,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,linear discriminant functional analysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Tina Hernandez-Boussard,,
http://purl.obolibrary.org/obo/OBI_0000040,drug role,drug,"a role borne by a molecular entity and is realized in a process of absorption by an organism  alters, or effects  (or is assumed to effect) a function(s) which inhere in an organism",false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,drug,,,,,,,,,,,,,,,"a role borne by a molecular entity and is realized in a process of absorption by an organism  alters, or effects  (or is assumed to effect) a function(s) which inhere in an organism","OBI, CDISC",,,,,,drug role,,"http://www.answers.com/topic/drug
   1. A substance used in the diagnosis, treatment, or prevention of a disease or as a component of a medication.
   2. Such a substance as recognized or defined by the U.S. Food, Drug, and Cosmetic Act.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000040,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,drug role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Role Branch,,
http://purl.obolibrary.org/obo/OBI_0000639,material separation objective,,is an objective to transform a material entity into spatially separated components.,false,,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,,,is an objective to transform a material entity into spatially separated components.,PPPB branch,,,,,,material separation objective,,The objective to obtain multiple aliquots of an enzyme preparation. The objective to obtain cells contained in a sample of blood.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000639,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,material separation objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PPPB branch,,
http://purl.obolibrary.org/obo/OBI_0600044,lavage,,A protocol application to separate cells and/or cellular secretions from an anatomical space by the introduction and removal of fluid,false,,,http://purl.obolibrary.org/obo/OBI_0600005|http://purl.obolibrary.org/obo/OBI_0600014,,http://purl.obolibrary.org/obo/OBI_0000639,,,,,,,,,,,,,,,,,A protocol application to separate cells and/or cellular secretions from an anatomical space by the introduction and removal of fluid,OBI branch derived,,,,,"This is not washing, in which case the material of interest is not the resulting fluid",lavage,,the collection of bronchoalveolar lavage fluid (BAL) from the lungs of mice in order to study the cytokines present,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600044,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,lavage,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0001907,immortalizing cell line transformation,,a genetic transformation of a cell line cell with transgenic constructs intended to confer the capability for indefinite propagation in culture,false,,,http://purl.obolibrary.org/obo/OBI_0600043,,,,,,,,,,,,,,,,,,,a genetic transformation of a cell line cell with transgenic constructs intended to confer the capability for indefinite propagation in culture,,,,,,,immortalizing cell line transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000428,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CLO_0000001,,,,OBI:0001907,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,immortalizing cell line transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001417,ChIP-chip by tiling array design,,A study design which aims to identify protein binding sites in genomic DNA by a combination of chromatin immunoprecipitation and tiling microarray (chip) assays.,false,,,http://purl.obolibrary.org/obo/OBI_0001403,,,,,,,,,,,,,,,,,,,A study design which aims to identify protein binding sites in genomic DNA by a combination of chromatin immunoprecipitation and tiling microarray (chip) assays.,Group: ArrayExpress production team,,,,,,ChIP-chip by tiling array design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001417,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ChIP-chip by tiling array design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0200063,characteristic path length calculation,,Quantifying subgraph navigability based on shortest-path length averaged over all pairs of subgraph vertices,false,,,http://purl.obolibrary.org/obo/OBI_0200085,,http://purl.obolibrary.org/obo/OBI_0200197,,,,,,,,,,,,,,,,,Quantifying subgraph navigability based on shortest-path length averaged over all pairs of subgraph vertices,PERSON: Tina Hernandez-Boussard,,,,,,characteristic path length calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200063,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,characteristic path length calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Tina Hernandez-Boussard,,
http://purl.obolibrary.org/obo/OBI_1110033,JAWS II cell line,,A cell line derived from mouse dendritic cells.,false,,,http://purl.obolibrary.org/obo/CLO_0009828,,,,,,,,,,,,,,,,,,,A cell line derived from mouse dendritic cells.,IEDB|http://www.atcc.org/ATCCAdvancedCatalogSearch/ProductDetails/tabid/452/Default.aspx?ATCCNum=CRL-11904&Template=cellBiology,,,,,,JAWS II cell line,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110033,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,JAWS II cell line,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000573,gradient pump system,,A pump system optimized for gradient chromatography.,false,,,http://purl.obolibrary.org/obo/OBI_0000589,,,,,,,,,,,,,,,,,,,A pump system optimized for gradient chromatography.,WEB:<http://www.buchi.com/Gradient-Pump-System.531.0.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01050,,,,,,gradient pump system,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000573,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,gradient pump system,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0600052,dialysis,,a protocol application that uses diffusion through a semi-permeable membrane to separate an input material into two fractions of different composition,false,,,http://purl.obolibrary.org/obo/OBI_0600014,,http://purl.obolibrary.org/obo/OBI_0000681,,,,,,,,,,,,,,,,,a protocol application that uses diffusion through a semi-permeable membrane to separate an input material into two fractions of different composition,OBI branch derived,,,,,,dialysis,,the use of a dialysis bag of select pore size to remove salt from collagen isolated from mouse cartilage,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600052,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,dialysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Kevin Clancy,,
http://purl.obolibrary.org/obo/OBI_0200114,euclidean distance calculation,,"An euclidean distance calculation is a similarity calculation that attaches to each pair of real number vectors of the same dimension n the square root of the sum of the square differences between corresponding components. The smaller this number, the more similar the two vectors are considered.",false,,,http://purl.obolibrary.org/obo/OBI_0200113,,,,,,,,,,,,,,,,,,,"An euclidean distance calculation is a similarity calculation that attaches to each pair of real number vectors of the same dimension n the square root of the sum of the square differences between corresponding components. The smaller this number, the more similar the two vectors are considered.",PERSON: Elisabetta Manduchi,,,,,,euclidean distance calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200114,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,euclidean distance calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0302910,prediction,,a process by which an  event or an entity is described before it actually happens or is being discovered and identified.,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,,,a process by which an  event or an entity is described before it actually happens or is being discovered and identified.,OBI,,,,,,prediction,,Prediction of TF target sites based on atomistic models of protein-DNA complexes. BMC Bioinformatics. 2008 Oct 16;9(1):436. PMID: 18922190,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000109,http://purl.obolibrary.org/obo/IAO_0000109,,,OBI:0302910,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,prediction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001995,chromatography assay measuring the association constant [KA] of a B cell epitope:antibody complex,association constant KA|chromatography|1/nM,A B cell epitope equilibrium association constant (KA) determination assay that uses an analytical chromatography assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001719,,,,,,,,,,,,,,,,,,,A B cell epitope equilibrium association constant (KA) determination assay that uses an analytical chromatography assay.,IEDB,,,,,,chromatography assay measuring the association constant [KA] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001995,,,,,,,,,,,,,,,,,,,,,,,,association constant KA|chromatography|1/nM,,,,,,,,,,,,,,,,,,,,,,chromatography assay measuring the association constant [KA] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/GO_0033036,macromolecule localization,,"Any process in which a macromolecule is transported to, or maintained in, a specific location.",false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,"Any process in which a macromolecule is transported to, or maintained in, a specific location.",,,,,,,macromolecule localization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0033036,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,macromolecule localization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0400089,Reflection,,"A Reflection is a sorter manufactured by iCyte. It uses digital signal processing, and can be configured with lasers of the users choice from among these excitation wavelengths: 355, 405,488, 532, 635nm. It accommodates up to 48 traditional PMTs. Options include an acousto-optical tunable filter (AOTF) and 16 channel spectrometer (370 to 730 nm). The various detection components can be uniquely configured across multiple Highly Automated Parallel Sorting (HAPS) modules. The Reflection can be used to analyse, sort, and collect cells.",false,,,http://purl.obolibrary.org/obo/OBI_0400099,,,,,,,,,,,,,,,,,,,"A Reflection is a sorter manufactured by iCyte. It uses digital signal processing, and can be configured with lasers of the users choice from among these excitation wavelengths: 355, 405,488, 532, 635nm. It accommodates up to 48 traditional PMTs. Options include an acousto-optical tunable filter (AOTF) and 16 channel spectrometer (370 to 730 nm). The various detection components can be uniquely configured across multiple Highly Automated Parallel Sorting (HAPS) modules. The Reflection can be used to analyse, sort, and collect cells.",http://www.i-cyt.com/reflection.htm,,,,,,Reflection,,Reflection at TSRI Flow Cytometry Core Facility,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400089,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Reflection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0001168,age since fertilization measurement datum,,"An age measurement datum that is the result of the measurement of the age of an organism since fertilization, the process of the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote.",false,,,http://purl.obolibrary.org/obo/OBI_0001167,,,,,,,,,,,,,,,,,,,"An age measurement datum that is the result of the measurement of the age of an organism since fertilization, the process of the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote.",MO_701 fertilization,,,,,Definition of fertilization comes from GO.,age since fertilization measurement datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001168,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,age since fertilization measurement datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000477,Varian GEMINI spectrometer,,An older Varian Broadband NMR spectrometer.,false,,,http://purl.obolibrary.org/obo/OBI_0000611,,,,,,,,,,,,,,,,,NMR instrument,,An older Varian Broadband NMR spectrometer.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400239,,,,,,Varian GEMINI spectrometer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000477,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Varian GEMINI spectrometer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/CHEBI_35729,gadolinium molecular entity,,,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,,,,,,,,gadolinium molecular entity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:35729,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,gadolinium molecular entity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/IAO_0000129,version number,,A version number is an information content entity which is a sequence of characters borne by part of each of a class of manufactured products or its packaging and indicates its order within a set of other products having the same name.,false,,,http://purl.obolibrary.org/obo/IAO_0000028,,,,,,,,,,,,,,,,,,,A version number is an information content entity which is a sequence of characters borne by part of each of a class of manufactured products or its packaging and indicates its order within a set of other products having the same name.,,,,,,"Note: we feel that at the moment we are happy with a general version number, and that we will subclass as needed in the future. For example, see 7. genome sequence version",version number,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000129,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,version number,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP: IAO,,
http://purl.obolibrary.org/obo/OBI_0001900,specimen identifier assigned by specimen repository,Specimen Repository Sample ID,A specimen identifier which is assigned by a specimen repository,false,,,http://purl.obolibrary.org/obo/OBI_0001616,,,,,,,,,,,,,,,,,,,A specimen identifier which is assigned by a specimen repository,NIAID GSCID-BRC metadata working group,,,,,,specimen identifier assigned by specimen repository,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001900,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,specimen identifier assigned by specimen repository,,,,,,Specimen Repository Sample ID,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000689,454 Genome Sequence 20,GS 20,"is a DNA sequencer which is manufactured by 454 Life Science Corporation and enables pyrosequencing to be performed. It comprises both optics and fluidics subsystems, which are
controlled by a computer subsystem. The fluidics subsystem ensures accurate reagent dispensing. It consists of a reagents cassette (which holds the reagent containers), a sipper manifold, pumps, valves, and debubblers. The fluidics subsystem flows the sequencing reagents across the wells of the PicoTiterPlate device, and moves the spent reagents from the PicoTiterPlate device to the waste receptacle. The optics subsystem consists of a CCD camera and a camera controller. The camera captures the light emitted in the wells of the PicoTiterPlate device during each step of the sequencing cycle, and sends the digital images to the computer subsystem for processing. The computer controls the other Sequencer subsystems, and processes the digital images sent by the camera to extract the DNA sequence information.",false,,,http://purl.obolibrary.org/obo/OBI_0400103,,,,GS 20,,,,,,,,,,,,,,,"is a DNA sequencer which is manufactured by 454 Life Science Corporation and enables pyrosequencing to be performed. It comprises both optics and fluidics subsystems, which are
controlled by a computer subsystem. The fluidics subsystem ensures accurate reagent dispensing. It consists of a reagents cassette (which holds the reagent containers), a sipper manifold, pumps, valves, and debubblers. The fluidics subsystem flows the sequencing reagents across the wells of the PicoTiterPlate device, and moves the spent reagents from the PicoTiterPlate device to the waste receptacle. The optics subsystem consists of a CCD camera and a camera controller. The camera captures the light emitted in the wells of the PicoTiterPlate device during each step of the sequencing cycle, and sends the digital images to the computer subsystem for processing. The computer controls the other Sequencer subsystems, and processes the digital images sent by the camera to extract the DNA sequence information.",,,,,,,454 Genome Sequence 20,,"PMID: 18946007.Pyrosequencing analysis of the oral microflora of healthy adults. 
Keijser BJ, Zaura E, Huse SM, van der Vossen JM, Schuren FH, Montijn RC, ten Cate JM, Crielaard W. J Dent Res. 2008 Nov;87(11):1016-20.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000689,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,454 Genome Sequence 20,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/GO_0016570,histone modification,,The covalent alteration of one or more amino acid residues within a histone protein.,false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,The covalent alteration of one or more amino acid residues within a histone protein.,,,,,,,histone modification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0016570,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,histone modification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000551,needle assembly,,"The needle assembly attached to the autosampler, comprises the injector needle that feeds a sample or carrier gas into the inlet",false,,,http://purl.obolibrary.org/obo/OBI_0000048,,,,,,,,,,,,,,,,,"chromatography device, check on definition !",,"The needle assembly attached to the autosampler, comprises the injector needle that feeds a sample or carrier gas into the inlet",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01065,,,,,,needle assembly,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000551,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,needle assembly,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001541,purified MHC direct binding assay measuring binding on rate [kon] of a MHC:ligand complex using fluorescence detection,on rate|purified MHC/direct/fluorescence|nM^-1s^-1,A purified MHC ligand binding on rate (kon) determination assay that uses fluorescence detection to measure direct ligand binding.,false,,,http://purl.obolibrary.org/obo/OBI_0001994|http://purl.obolibrary.org/obo/OBI_0001499,,,,,,,,,,,,,,,,,,,A purified MHC ligand binding on rate (kon) determination assay that uses fluorescence detection to measure direct ligand binding.,IEDB,,,,,,purified MHC direct binding assay measuring binding on rate [kon] of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001541,,,,,,,,,,,,,,,,,,,,,,,,on rate|purified MHC/direct/fluorescence|nM^-1s^-1,,,,,,,,,,,,,,,,,,,,,,purified MHC direct binding assay measuring binding on rate [kon] of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001539,cell bound MHC competitive binding assay measuring equilibrium dissociation constant [KD] of a MHC:ligand complex using fluorescence detection,dissociation constant KD|cellular MHC/competitive/fluorescence|nM,A cell bound MHC ligand binding equilibrium dissociation constant (KD) determination assay that uses fluorescence detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation.,false,,,http://purl.obolibrary.org/obo/OBI_0001988|http://purl.obolibrary.org/obo/OBI_0001499,,,,,,,,,,,,,,,,,,,A cell bound MHC ligand binding equilibrium dissociation constant (KD) determination assay that uses fluorescence detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation.,IEDB,,,,,,cell bound MHC competitive binding assay measuring equilibrium dissociation constant [KD] of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001539,,,,,,,,,,,,,,,,,,,,,,,,dissociation constant KD|cellular MHC/competitive/fluorescence|nM,,,,,,,,,,,,,,,,,,,,,,cell bound MHC competitive binding assay measuring equilibrium dissociation constant [KD] of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0400013,band pass filter,,A band pass filter is an optical filter that passes wavelengths of light within a certain range and rejects (attenuates) frequencies outside that range. The passed wavelengths are indicated in the specifications of the filter and its name. A 480/20 band-pass filter pass light with at wavelengths of 460 to 500 nm and attenuates all others.,false,,,http://purl.obolibrary.org/obo/OBI_0400079,,,,,,,,,,,,,,,,,,,A band pass filter is an optical filter that passes wavelengths of light within a certain range and rejects (attenuates) frequencies outside that range. The passed wavelengths are indicated in the specifications of the filter and its name. A 480/20 band-pass filter pass light with at wavelengths of 460 to 500 nm and attenuates all others.,http://en.wikipedia.org/wiki/Band_pass_filter,,,,,,band pass filter,,"530/30 BP filter, 585/42 BP filter",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400013,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,band pass filter,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:John Quinn,,
http://purl.obolibrary.org/obo/OBI_0000692,recombination enzyme based cloning,,a recombination enzyme based cloning is a recombinant vector cloning process that uses complementary nucleotide sequences in both the insert genetic material and the cloning vector with a recombination enzyme to directly create a recombinant vector,false,,,http://purl.obolibrary.org/obo/OBI_0600064,,,,,,,,,,,,,,,,,,,a recombination enzyme based cloning is a recombinant vector cloning process that uses complementary nucleotide sequences in both the insert genetic material and the cloning vector with a recombination enzyme to directly create a recombinant vector,,,,,,,recombination enzyme based cloning,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000692,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,recombination enzyme based cloning,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001253,biological activity assay measuring interleukin-9 production by T cells,IL-9 release|biological activity,A T cell epitope specific cytokine production assay that detects interleukin-9 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects interleukin-9 production by T cells.,IEDB,,,,,,biological activity assay measuring interleukin-9 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001253,,,,,,,,,,,,,,,,,,,,,,,,IL-9 release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring interleukin-9 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/GO_0006006,glucose metabolic process,,"The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.",false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,"The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.",,,,,,,glucose metabolic process,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0006006,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,glucose metabolic process,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0400068,LSR2,,"A LSR2 is a sorter manufactured by Becton Dickinson. It features digital electronics, a solid state 488 nm blue laser and optionally can also have any combination of solid state UV (355 nm) and violet (405 nm) lasers and the a HeNe (633 nm) ion laser. The LSR2 has the filters and PMTs to work with 13 fluorescent parameters. The LSR II is one of the most common sorters in use.",false,,,http://purl.obolibrary.org/obo/OBI_0400099,,,,,,,,,,,,,,,,,,,"A LSR2 is a sorter manufactured by Becton Dickinson. It features digital electronics, a solid state 488 nm blue laser and optionally can also have any combination of solid state UV (355 nm) and violet (405 nm) lasers and the a HeNe (633 nm) ion laser. The LSR2 has the filters and PMTs to work with 13 fluorescent parameters. The LSR II is one of the most common sorters in use.",http://www.bdbiosciences.com/external_files/is/doc/mkt_lit/brochures/live/web_enabled/SJ-0142-00LSR2.pdf,,,,,,LSR2,,LSR2 at TSRI Flow Cytometry Core Facility,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400068,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,LSR2,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0000949,accessed material role,,is realized in a planned process where the bearer participates,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,,,is realized in a planned process where the bearer participates,,,,,,"AR: rent a DNA sequencer for a period of time. two realizations, payment for the service and also when the person who pays for the service uses it",accessed material role,,"the role of the  DNA sequencer to which someone gets access to a period of time, e.g. by payment, or other mechanism",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000949,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,accessed material role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000381,liquid filter function,,"A liquid filter function is a filter function which prevents the flow of solid objects, defined by specific qualities, in a liquid-solid mixture",false,,,http://purl.obolibrary.org/obo/OBI_0000378,,,,,,,,,,,,,,,,,,,"A liquid filter function is a filter function which prevents the flow of solid objects, defined by specific qualities, in a liquid-solid mixture",,,,,,,liquid filter function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000381,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,liquid filter function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Frank Gibson,,
http://purl.obolibrary.org/obo/OBI_0100064,screening library,,a screening library is a collection of materials engineered to identify qualities of a subset of its members during a screening process?,false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,,,,,,,,,,,,,,7/13/09: Need to clarify if this meets reagent role definition,,a screening library is a collection of materials engineered to identify qualities of a subset of its members during a screening process?,GROUP: IEDB,,,,,"PRS: 22-02-2008: while working on definition of cDNA library and looking at current example of usage, a screening library should be a defined class -> any material library which has input_role in a screening protocol application
change biomaterial to material in definition",screening library,,"PMID: 15615535.J Med Chem. 2004 Dec 30;47(27):6864-74.A screening library for peptide activated G-protein coupled receptors. 1. The test set. [cdna_library, phage display library]",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0100064,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,screening library,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000174,study group role,study group population,"a study population role where the bearer is a population of material entities and the role is realized in the implementation of a study design wherein the entities bearing the study population role are observed or subjected to intervention according to the study design and are biological replicates, i.e. they receive the same treatment under the protocol",false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,study group population,,,,,,,,,,,,,,,"a study population role where the bearer is a population of material entities and the role is realized in the implementation of a study design wherein the entities bearing the study population role are observed or subjected to intervention according to the study design and are biological replicates, i.e. they receive the same treatment under the protocol",,,,,,,study group role,,The group of randomized participants that are assigned to a treatment arm of the trial,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000174,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,study group role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0200061,data imputation,,"Imputation is a means of filling in missing data values from a predictive distribution of the missing values.  The predictive distribution can be created either based on a formal statistical model (i,e, a multivariate normal distribution) or an algorithm.",false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,"Imputation is a means of filling in missing data values from a predictive distribution of the missing values.  The predictive distribution can be created either based on a formal statistical model (i,e, a multivariate normal distribution) or an algorithm.","ARTICLE: Little, RJA and Rubin, DB (2002).  Statistical Analysis with Missing Data, Second Edition.  John Wiley: Hoboken New Jersey, pp. 59-60.",,,,,,data imputation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200061,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,data imputation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Monnie McGee,,
http://purl.obolibrary.org/obo/OBI_0000623,NMR spectroscopy,Nuclear magnetic resonance spectroscopy,NMR spectroscopy is a process which exploits the magnetic properties of certain nuclei (those with a spin) to resonate when placed in particular magnetic field conditions. Instruments recording NMR spectrum and sets of analysis can be used to deduce  identity of chemical as well as composition of complex chemical mixtures.,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,http://purl.obolibrary.org/obo/OBI_0000441,,Nuclear magnetic resonance spectroscopy,,,,,,,,,,,,,,,NMR spectroscopy is a process which exploits the magnetic properties of certain nuclei (those with a spin) to resonate when placed in particular magnetic field conditions. Instruments recording NMR spectrum and sets of analysis can be used to deduce  identity of chemical as well as composition of complex chemical mixtures.,adapted from Wikipedia,,,,,,NMR spectroscopy,,"Metabolic profiling studies on the toxicological effects of realgar in rats by (1)H NMR spectroscopy.  Wei L, Liao P, Wu H, Li X, Pei F, Li W, Wu Y. Toxicol Appl Pharmacol. 2008 Nov 25. PMID: 19073202",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000623,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NMR spectroscopy,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0200013,loess global transformation one-channel,,A loess global transformation one-channel is a loess global transformation in the special case where the input is the result of an MA transformation applied to intensities from two related one-channel assays.,false,,,http://purl.obolibrary.org/obo/OBI_0200023,,,,,,,,,,,,,,,,,,,A loess global transformation one-channel is a loess global transformation in the special case where the input is the result of an MA transformation applied to intensities from two related one-channel assays.,OTHER: Editor's generalization based on MGED Ontology term,,,,,,loess global transformation one-channel,,"Loess global normalization applied to data from two one-channel expression microarray assays, where the curve is obtained using all reporters. The goal is to remove intensity-dependent biases.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200013,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,loess global transformation one-channel,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0500024,standard compliance rule,,a  standard compliance rule is a compliance rule which defines conformity to a representation standard,false,,,http://purl.obolibrary.org/obo/OBI_0500023,,,,,,,,,,,,,,,,,,,a  standard compliance rule is a compliance rule which defines conformity to a representation standard,PRS,,,,,,standard compliance rule,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500024,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,standard compliance rule,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PRS,,
http://purl.obolibrary.org/obo/IAO_0000100,data set,,A data item that is an aggregate of other data items of the same type that have something in common. Averages and distributions can be determined for data sets.,false,,,http://purl.obolibrary.org/obo/IAO_0000027,,,,,,,,,,,,,,,,,,,A data item that is an aggregate of other data items of the same type that have something in common. Averages and distributions can be determined for data sets.,OBI_0000042|group:OBI,,,,,"2014-05-05: Data sets are aggregates and thus must include two or more data items. We have chosen not to add logical axioms to make this restriction.|2009/10/23 Alan Ruttenberg. The intention is that this term represent collections of like data. So this isn't for, e.g. the whole contents of a cel file, which includes parameters, metadata etc. This is more like java arrays of a certain rather specific type",data set,,Intensity values in a CEL file or from multiple CEL files comprise a data set (as opposed to the CEL files themselves).,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,data set,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Allyson Lister|person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0001050,RNA extraction/purification instrument,,A device that is used to isolate and collect RNA for subsequent molecular analysis.,false,,,http://purl.obolibrary.org/obo/OBI_0001114,,,,,,,,,,,,,,,,,,,A device that is used to isolate and collect RNA for subsequent molecular analysis.,PERSON: Erik Segerdell,,,,,,RNA extraction/purification instrument,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001050,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,RNA extraction/purification instrument,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0000419,reverse transcriptase,,"enzyme and has_function some GO:0003964 (RNA-directed DNA polymerase
activity)",false,,,http://purl.obolibrary.org/obo/OBI_0000427,,,,,,,,,,,,,,,,,,,"enzyme and has_function some GO:0003964 (RNA-directed DNA polymerase
activity)",group:OBI,,,,,,reverse transcriptase,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000419,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,reverse transcriptase,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0000990,electron microscope,,A microscope that produces an image of an object by targeting it with an electron beam,false,,,http://purl.obolibrary.org/obo/OBI_0400169,,,,,,,,,,,,,,,,,,,A microscope that produces an image of an object by targeting it with an electron beam,,,,,,,electron microscope,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000990,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,electron microscope,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0001631,relational spatial quality,,A quality of related physical entities inhering in a bearer by virtue of the bearer's pertaining to or involving or having the nature of space in relation to another entity.,false,,,http://purl.obolibrary.org/obo/PATO_0001238,,,,,,,,,,,,,,,,,,,A quality of related physical entities inhering in a bearer by virtue of the bearer's pertaining to or involving or having the nature of space in relation to another entity.,,,,,,,relational spatial quality,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001631,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,relational spatial quality,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0001632,anterior to,frontal,A spatial quality inhering in a bearer by virtue of the bearer's being located toward the front of an organism relative to another entity.,false,,,http://purl.obolibrary.org/obo/PATO_0001631,,,,frontal,,,,,,,,,,,,,,,A spatial quality inhering in a bearer by virtue of the bearer's being located toward the front of an organism relative to another entity.,,,,,,,anterior to,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001632,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,anterior to,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_1110048,cultured CD3- T cell population,CD3- T cell culture sample,A T cell population characterized by not expressing the CD3 molecule on its surface.,false,,,http://purl.obolibrary.org/obo/OBI_0001875,,,,CD3- T cell culture sample,,,,,,,,,,,,,,,A T cell population characterized by not expressing the CD3 molecule on its surface.,IEDB,,,,,,cultured CD3- T cell population,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110048,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cultured CD3- T cell population,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000714,graph of vertices,,A construct that consists of many nodes connected with edges. The edges represent a relationship between the objects represented by the nodes.  A graph can be equivalently represented as a matrix.,false,,,http://purl.obolibrary.org/obo/IAO_0000038,,,,,,,,,,,,,,,,,,,A construct that consists of many nodes connected with edges. The edges represent a relationship between the objects represented by the nodes.  A graph can be equivalently represented as a matrix.,WEB: http://mitpress.mit.edu/books/FLAOH/cbnhtml/glossary-G.html,,,,,,graph of vertices,,"For example, if the nodes are cities, then the edges may have numerical values that correspond to the distances between the cities.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000714,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,graph of vertices,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Chris Stoeckert|Bjoern Peters,,
http://purl.obolibrary.org/obo/IAO_0000047,obsolete2_text based digital entity,,A text based digital entity is a digital entity that is encoded so that it only contains text characters.,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,A text based digital entity is a digital entity that is encoded so that it only contains text characters.,group:OBI|OBI_0000132,,,,,"digital_entity|3/22/2009 Alan Ruttenberg, obsoleted per http://groups.google.com/group/information-ontology/browse_thread/thread/789ad4b7708d5cf4
superclass was 'digital document'",obsolete2_text based digital entity,,"XML file, C++ source code file",,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,IAO:0000047,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete2_text based digital entity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0001244,ELISA measuring epitope specific interleukin-23 production by T cells,IL-23 release|ELISA,An assay of epitope specific interleukin-23 production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001363,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-23 production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific interleukin-23 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001244,,,,,,,,,,,,,,,,,,,,,,,,IL-23 release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific interleukin-23 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001100,microcentrifuge,,"A type of centrifuge that is designed for small tubes (0.2 ml to 2.0 ml), has a compact design, and has a small footprint.",false,,,http://purl.obolibrary.org/obo/OBI_0400106,,,,,,,,,,,,,,,,,,,"A type of centrifuge that is designed for small tubes (0.2 ml to 2.0 ml), has a compact design, and has a small footprint.",http://en.wikipedia.org/wiki/Laboratory_centrifuge,,,,,,microcentrifuge,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,microcentrifuge,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/GO_0051276,chromosome organization,,"A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.",false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,"A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.",,,,,,,chromosome organization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0051276,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,chromosome organization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_1110128,immune epitope assay,immune epitope assay,An assay that detects the binding of an epitope to an adaptive immune receptor or a immune response process resulting from such a binding event,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,An assay that detects the binding of an epitope to an adaptive immune receptor or a immune response process resulting from such a binding event,IEDB,,,,,,immune epitope assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110128,,,,,,,,,,,,,,,,,,,,,,,,immune epitope assay,,,,,,,,,,,,,,,,,,,,,,immune epitope assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001526,epitope specific interleukin-17A production by T cells,,A process of interleukin-17A production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/OBI_1110193|http://purl.obolibrary.org/obo/GO_0097087,,,,,,,,,,,,,,,,,Date: 2011-11-10; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mappings: assay_mappings.owl,,A process of interleukin-17A production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific interleukin-17A production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001526,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific interleukin-17A production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000497,sample inlet,,The column inlet (or injector) provides the means to introduce a sample into a continuous flow of carrier gas. The inlet is a piece of hardware attached to the column head.,false,,,http://purl.obolibrary.org/obo/OBI_0000048,,,,,,,,,,,,,,,,,chromatography device,,The column inlet (or injector) provides the means to introduce a sample into a continuous flow of carrier gas. The inlet is a piece of hardware attached to the column head.,WEB:<http://en.wikipedia.org/wiki/Gas_chromatography#Inlets>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01044,,,,,,sample inlet,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000497,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sample inlet,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_1110050,cultured CD4- T cell population,CD4- T cell culture sample,A T cell population characterized by not expressing the CD4 molecule on its surface.,false,,,http://purl.obolibrary.org/obo/OBI_0001875,,,,CD4- T cell culture sample,,,,,,,,,,,,,,,A T cell population characterized by not expressing the CD4 molecule on its surface.,IEDB,,,,,,cultured CD4- T cell population,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110050,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cultured CD4- T cell population,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001629,grant identifier,grant ID,A CRID symbol used to identify a grant.,false,,,http://purl.obolibrary.org/obo/IAO_0000577,,,,,,,,,,,,,,,,,,,A CRID symbol used to identify a grant.,NIAID GSCID-BRC metadata working group,,,,,,grant identifier,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001629,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,grant identifier,,,,,,grant ID,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/NCBITaxon_9031,Gallus gallus,chickens|bantam|chicken,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_32524,,,,chickens|bantam|chicken,,,,,,,,,,,,,,,,,,,,,,Gallus gallus,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:9031,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Gallus gallus,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001134,agarose gel electrophoresis system,,"A gel electrophoresis system that is used to separate DNA or RNA molecules by size, achieved by moving negatively charged nucleic acid molecules through an agarose matrix with an electric field.",false,,,http://purl.obolibrary.org/obo/OBI_0001053,,,,,,,,,,,,,,,,,,,"A gel electrophoresis system that is used to separate DNA or RNA molecules by size, achieved by moving negatively charged nucleic acid molecules through an agarose matrix with an electric field.",http://en.wikipedia.org/wiki/Agarose_gel_electrophoresis,,,,,,agarose gel electrophoresis system,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001134,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,agarose gel electrophoresis system,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0000584,anion exchange column,,An anion exchange column is a chromatography column that is used in anion exchange chromatography and which enables the separation of anion mixtures.,false,,,http://purl.obolibrary.org/obo/OBI_0000560,,,,,,,,,,,,,,,,,,,An anion exchange column is a chromatography column that is used in anion exchange chromatography and which enables the separation of anion mixtures.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01095,,,,,,anion exchange column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000584,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,anion exchange column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0200016,sine transformation,,"A sine transformation is a data transformation which consists in applying the sine function to a (one dimensional) real number input. The sine function is one of the basic trigonometric functions and a definition is provided, e.g., at http://mathworld.wolfram.com/Sine.html.",false,,,http://purl.obolibrary.org/obo/OBI_0200169,,http://purl.obolibrary.org/obo/OBI_0200167,,,,,,,,,,,,,,,,,"A sine transformation is a data transformation which consists in applying the sine function to a (one dimensional) real number input. The sine function is one of the basic trigonometric functions and a definition is provided, e.g., at http://mathworld.wolfram.com/Sine.html.",WEB: http://mathworld.wolfram.com/Sine.html,,,,,,sine transformation,,"sine(0)=0, sine(pi/2)=1, sine(pi)=0, sine(3*pi/2)=-1, sine(pi/6)=1/2, sine(x+2*k*pi)=sine(x) where k is any integer, etc.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200016,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sine transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0001098,ultrasound machine,,"A device that is used to visualize subcutaneous body structures including tendons, muscles, joints, vessels and internal organs.",false,,,http://purl.obolibrary.org/obo/OBI_0000398,,,,,,,,,,,,,,,,,,,"A device that is used to visualize subcutaneous body structures including tendons, muscles, joints, vessels and internal organs.",http://en.wikipedia.org/wiki/Sonography,,,,,,ultrasound machine,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453|http://purl.obolibrary.org/obo/OBI_0000397,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001098,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ultrasound machine,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001415,epitope specific interleukin-9 production by T cells,,A process of interleukin-9 production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/OBI_0001193|http://purl.obolibrary.org/obo/GO_0032638,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of interleukin-9 production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific interleukin-9 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001415,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific interleukin-9 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_1110185,epitope specific IFN-g release by T cells,,A biological process where T cells produce IFNg resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0032609|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,,,A biological process where T cells produce IFNg resulting from the recognition of a T cell epitope.,IEDB,,,,,,epitope specific IFN-g release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110185,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific IFN-g release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000658,data representational model,data structure specification|data structure,Data representational model is an information content entity of the  relationships between data items. A data representational model is encoded in a data format specification such as for cytoscape or biopax.,false,,,http://purl.obolibrary.org/obo/IAO_0000033,,,,data structure specification|data structure,,,,,,,,,,,,,2009-02-28: work on this term has been finalized during the OBI workshop winter 2009,,Data representational model is an information content entity of the  relationships between data items. A data representational model is encoded in a data format specification such as for cytoscape or biopax.,GROUP: OBI,,,,,,data representational model,,gene regulatory graph model|protein interaction network|phylogenetic tree,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000658,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,data representational model,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Melanie Courtot,,
http://purl.obolibrary.org/obo/CHEBI_33376,terbium atom,,A lanthanoid atom that has formula Tb.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,A lanthanoid atom that has formula Tb.,,,,,,,terbium atom,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:33376,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,terbium atom,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001083,multichannel electronic pipette,,A multichannel pipette that can be programmed by the user to aspirate a volume of liquid reagent or sample and dispense the aspirated volume or a series of aliquots in successive dispensing operations.,false,,,http://purl.obolibrary.org/obo/OBI_0001118,,,,,,,,,,,,,,,,,,,A multichannel pipette that can be programmed by the user to aspirate a volume of liquid reagent or sample and dispense the aspirated volume or a series of aliquots in successive dispensing operations.,http://www.faqs.org/patents/app/20090196797,,,,,,multichannel electronic pipette,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001083,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,multichannel electronic pipette,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001488,epitope tolerance induction experiment,tolerance induction,An efficacy of epitope intervention experiment that tests the ability of the intervention to decrease an existing immune response ,false,,,http://purl.obolibrary.org/obo/OBI_0001178,,,,,,,,,,,,,,,,,,,An efficacy of epitope intervention experiment that tests the ability of the intervention to decrease an existing immune response ,IEDB,,,,,,epitope tolerance induction experiment,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001488,,,,,,,,,,,,,,,,,,,,,,,,tolerance induction,,,,,,,,,,,,,,,,,,,,,,epitope tolerance induction experiment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000448,packed column,,A packed column is a chromatography column where the particles of the solid stationary phase or the support coated with a liquid stationary phase may fill the whole inside volume of the tube.,false,,,http://purl.obolibrary.org/obo/OBI_0000038,,,,,,,,,,,,,,,,,,,A packed column is a chromatography column where the particles of the solid stationary phase or the support coated with a liquid stationary phase may fill the whole inside volume of the tube.,WEB:<http:www.iupac.org/publications/pac/1993/pdf/6504x0819.pdf>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01218,,,,,,packed column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000448,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,packed column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001878,establishing primary cell culture,,"an establishing cell culture process whereby cells explanted directly from an organismal source or specimen, and placed in culture for maintenance or propagation as a primary cell culture|Cells are originally plated at a certain concentration referred to as seeding density. Upon a first passage this primary culture becomes a secondary cell culture that can be propagated to become a stable and homogneous cell line. This class covers establishment of primary cultures from any native cell - 'in vivo' cells isolated from some multicellular organism, or 'in environment' unicellular organisms isolated from some natural environment.",false,,,http://purl.obolibrary.org/obo/OBI_0600036,,,,,,,,,,,,,,,,,,,"an establishing cell culture process whereby cells explanted directly from an organismal source or specimen, and placed in culture for maintenance or propagation as a primary cell culture",PERSON: Matthew Brush,,,,,,establishing primary cell culture,,"Effects of establishing cell cultures and cell culture conditions on the proliferative life span of human fibroblasts isolated from different tissues and donors of different ages.
Exp Cell Res. 2002 Apr 1;274(2):275-87. PMID: 11900488

When harvesting blood from a human, isolating T cells, and then limited dilution cloning of the cells, the establishing_cell_culture step comprises preparing the cells at a certain dilution and plating them in a container with growth medium.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100061,,,OBI:0001878,,,,,,,,,,,,,,,,,,"Cells are originally plated at a certain concentration referred to as seeding density. Upon a first passage this primary culture becomes a secondary cell culture that can be propagated to become a stable and homogneous cell line. This class covers establishment of primary cultures from any native cell - 'in vivo' cells isolated from some multicellular organism, or 'in environment' unicellular organisms isolated from some natural environment.",,,,,,,,,,,,,,,,,,,,,,,,,,,,establishing primary cell culture,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000591,Bruker BEST NMR system,Bruker Efficient Sample Transfer NMR,"The introduction of biological screening and combinatorial chemistry for chemical synthesis has also introduced new requirements for NMR automation, e.g., the use of well plates for sample input, increased demands on throughput, and the need for quick and simple interpretation of the acquired NMR data.",false,,,http://purl.obolibrary.org/obo/OBI_0000464,,,,Bruker Efficient Sample Transfer NMR,,,,,,,,,,,,,NMR instrument,,"The introduction of biological screening and combinatorial chemistry for chemical synthesis has also introduced new requirements for NMR automation, e.g., the use of well plates for sample input, increased demands on throughput, and the need for quick and simple interpretation of the acquired NMR data.",WEB:<http://www.bruker-biospin.com/automation.html>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400206,,,,,,Bruker BEST NMR system,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000591,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker BEST NMR system,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001998,immunohistochemistry assay measuring binding of a B cell epitope:antibody complex,qualitative binding|immunohistochemistry,A B cell epitope qualitative binding to antibody assay that uses an immunohistochemistry assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001703|http://purl.obolibrary.org/obo/OBI_0001652,,,,,,,,,,,,,,,,,,,A B cell epitope qualitative binding to antibody assay that uses an immunohistochemistry assay.,IEDB,,,,,,immunohistochemistry assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001998,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|immunohistochemistry,,,,,,,,,,,,,,,,,,,,,,immunohistochemistry assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001137,protein sequencer,,An device that is used to determine the order of amino acids in protein sequences.,false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,An device that is used to determine the order of amino acids in protein sequences.,PERSON: Erik Segerdell,,,,,,protein sequencer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001137,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,protein sequencer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0200017,cosine transformation,,"A cosine transformation is a data transformation which consists in applying the cosine function to a (one dimensional) real number input. The cosine function is one of the basic trigonometric functions and a definition is provided, e.g., at http://mathworld.wolfram.com/Cosine.html.",false,,,http://purl.obolibrary.org/obo/OBI_0200169,,http://purl.obolibrary.org/obo/OBI_0200167,,,,,,,,,,,,,,,,,"A cosine transformation is a data transformation which consists in applying the cosine function to a (one dimensional) real number input. The cosine function is one of the basic trigonometric functions and a definition is provided, e.g., at http://mathworld.wolfram.com/Cosine.html.",WEB: http://mathworld.wolfram.com/Cosine.html,,,,,,cosine transformation,,"cosine(0)=1, cosine(pi/2)=0, cosine(pi)=-1, cosine(3*pi/2)=0, cosine(pi/3)=1/2, cosine(x+2*k*pi)=cosine(x) where k is any integer, etc.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200017,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cosine transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001566,50% dissociation of binding temperature (Tm),melting temperature (Tm),"A binding datum that specifies the temperature at which half of the binding partners are forming a complex and the other half are unbound. 
",false,,,http://purl.obolibrary.org/obo/OBI_0001181,,,,melting temperature (Tm),,,,,,,,,,,,,,,"A binding datum that specifies the temperature at which half of the binding partners are forming a complex and the other half are unbound. 
",IEDB,,,,,,50% dissociation of binding temperature (Tm),,"Preparing a complex of a purified HLA-A*02:01 bound to a specific peptide ligand, varying the temperature while detecting the fraction of bound complexes with a  complex conformation specific antibody, and interpolating the temperature at which 50% of complexes are dissociated.  
",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,http://purl.obolibrary.org/obo/UO_0000005,,,,,,,,,,,,,,,,,,,,,OBI:0001566,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,50% dissociation of binding temperature (Tm),,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Bjoern Peters, Randi Vita",,
http://purl.obolibrary.org/obo/BFO_0000030,object,,,false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,Object,object,,,,,,,,,,,,,,,,,"BFO 2 Reference: Each object is such that there are entities of which we can assert unproblematically that they lie in its interior, and other entities of which we can assert unproblematically that they lie in its exterior. This may not be so for entities lying at or near the boundary between the interior and exterior. This means that two objects – for example the two cells depicted in Figure 3 – may be such that there are material entities crossing their boundaries which belong determinately to neither cell. Something similar obtains in certain cases of conjoined twins (see below).|BFO 2 Reference: ‘objects’ are sometimes referred to as ‘grains’ [74|BFO 2 Reference: an object is a maximal causally unified material entity|BFO 2 Reference: To say that b is causally unified means: b is a material entity which is such that its material parts are tied together in such a way that, in environments typical for entities of the type in question,if c, a continuant part of b that is in the interior of b at t, is larger than a certain threshold size (which will be determined differently from case to case, depending on factors such as porosity of external cover) and is moved in space to be at t at a location on the exterior of the spatial region that had been occupied by b at t, then either b’s other parts will be moved in coordinated fashion or b will be damaged (be affected, for example, by breakage or tearing) in the interval between t and t.causal changes in one part of b can have consequences for other parts of b without the mediation of any entity that lies on the exterior of b. Material entities with no proper material parts would satisfy these conditions trivially. Candidate examples of types of causal unity for material entities of more complex sorts are as follows (this is not intended to be an exhaustive list):CU1: Causal unity via physical coveringHere the parts in the interior of the unified entity are combined together causally through a common membrane or other physical covering\. The latter points outwards toward and may serve a protective function in relation to what lies on the exterior of the entity [13, 47|BFO 2 Reference: BFO rests on the presupposition that at multiple micro-, meso- and macroscopic scales reality exhibits certain stable, spatially separated or separable material units, combined or combinable into aggregates of various sorts (for example organisms into what are called ‘populations’). Such units play a central role in almost all domains of natural science from particle physics to cosmology. Many scientific laws govern the units in question, employing general terms (such as ‘molecule’ or ‘planet’) referring to the types and subtypes of units, and also to the types and subtypes of the processes through which such units develop and interact. The division of reality into such natural units is at the heart of biological science, as also is the fact that these units may form higher-level units (as cells form multicellular organisms) and that they may also form aggregates of units, for example as cells form portions of tissue and organs form families, herds, breeds, species, and so on. At the same time, the division of certain portions of reality into engineered units (manufactured artifacts) is the basis of modern industrial technology, which rests on the distributed mass production of engineered parts through division of labor and on their assembly into larger, compound units such as cars and laptops. The division of portions of reality into units is one starting point for the phenomenon of counting.",object,b is an object means: b is a material entity which manifests causal unity of one or other of the types CUn listed above & is of a type (a material universal) instances of which are maximal relative to this criterion of causal unity. (axiom label in BFO2 Reference: [024-001]),organism|organelle|cell|atom|cells and organisms|molecule|grain of sand|planet|solid portions of matter|engineered artifacts|star,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000030,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,object,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000504,sample injection system,,An automated chromatography system that injects the sample into the chromatography columns in order to increase speed and minimize human involvement in the purification process for  better reproducibility.,false,,,http://purl.obolibrary.org/obo/OBI_0000048,,,,,,,,,,,,,,,,,chromatography device,,An automated chromatography system that injects the sample into the chromatography columns in order to increase speed and minimize human involvement in the purification process for  better reproducibility.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01057,,,,,,sample injection system,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000504,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sample injection system,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000186,protocol optimization objective,,Protocol_optimization is a protocol_testing_objective role describing a study designed to identify the best protocol.  This may be carried out by comparing different protocols or by modifying the parameters used within a single protocol.,false,,,http://purl.obolibrary.org/obo/OBI_0000096,,,,,,,,,,,,,,,,,,,Protocol_optimization is a protocol_testing_objective role describing a study designed to identify the best protocol.  This may be carried out by comparing different protocols or by modifying the parameters used within a single protocol.,,,,,,,protocol optimization objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000186,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,protocol optimization objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0000367,light emission function,,A light emission function is an excitation function to excite a material to a specific excitation state that it emits light.,false,,,http://purl.obolibrary.org/obo/OBI_0000374,,,,,,,,,,,,,,,,,,,A light emission function is an excitation function to excite a material to a specific excitation state that it emits light.,,,,,,,light emission function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000367,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,light emission function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bill Bug|Daniel Schober|Frank Gibson|Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0001677,epitope specific granulysin production by T cells,,A process of granulysin production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0036262,,,,,,,,,,,,,,,,,Date: 2011-6-24; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mappings: MMExpressionsTcell.txt,,A process of granulysin production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific granulysin production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001677,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific granulysin production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001880,organization of specimen provider principal investigator,Sample Provider PI's Institution,An organization that is the affiliation of the principal investigator providing the specimens for the investigation,false,,,http://purl.obolibrary.org/obo/OBI_0000245,,,,,,,,,,,,,,,,,,,An organization that is the affiliation of the principal investigator providing the specimens for the investigation,NIAID GSCID-BRC metadata working group,,,,,,organization of specimen provider principal investigator,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001880,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,organization of specimen provider principal investigator,,,,,,Sample Provider PI's Institution,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/GO_0001047,core promoter binding,,Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for the basal transcription machinery. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.,false,,,http://purl.obolibrary.org/obo/OBI_0001588,,,,,,,,,,,,,,,,,,,Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for the basal transcription machinery. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.,,,,,,,core promoter binding,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0001047,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,core promoter binding,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001862,reduced representation bisulfite sequencing assay,reduced representation bisulfite-seq|RRBS|RRBS assay,A bisulfite sequencing assay that identifies genomic methylation patterns by using a bisulfite based protocol that enriches CG-rich parts of the genome.,false,,,http://purl.obolibrary.org/obo/OBI_0000748,,,,reduced representation bisulfite-seq|RRBS|RRBS assay,,,,,,,,,,,,,,,A bisulfite sequencing assay that identifies genomic methylation patterns by using a bisulfite based protocol that enriches CG-rich parts of the genome.,Meissner et al. Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis. Nucleic Acids Res. 2005; 33(18): 5868–5877. [PMCID: PMC1258174],,,,,,reduced representation bisulfite sequencing assay,,Meissner et al. Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis. Nucleic Acids Res. 2005; 33(18): 5868–5877. [PMCID: PMC1258174],,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000711|http://purl.obolibrary.org/obo/OBI_0600050,,,,,,,,,,,,,,,,OBI:0001862,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,reduced representation bisulfite sequencing assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/NCBITaxon_4896,Schizosaccharomyces pombe,fission yeast,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_4890,,,,fission yeast,,,,,,,,,,,,,,,,,,,,,,Schizosaccharomyces pombe,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:4896,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Schizosaccharomyces pombe,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/NCBITaxon_4890,Ascomycota,ascomycetes|sac fungi,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_33154,,,,ascomycetes|sac fungi,,,,,,,,,,,,,,,,,,,,,,Ascomycota,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:4890,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Ascomycota,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001037,obsolete_specimen fixation function,,"A specimen 
fixation function is a function that holds or fastens an entity in a fixed position.|duplicate term",true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,"A specimen 
fixation function is a function that holds or fastens an entity in a fixed position.",,,,,,,obsolete_specimen fixation function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000227,,,,,,,,,,,,,,,,,,OBI:0001037,,,,,,,,,,,,,,,,,,duplicate term,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_specimen fixation function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,EAGLE-I,,
http://purl.obolibrary.org/obo/OBI_0000946,sterilization function,,a function to remove viable organisms from an input material,false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,a function to remove viable organisms from an input material,,,,,,,sterilization function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000946,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sterilization function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0100061,primary cultured cell population,primary cell culture|primary cell culture sample,"A cultured cell population comprised of cells expanded directly from living tissue prior to being passaged.

",false,,,http://purl.obolibrary.org/obo/OBI_0100060,,,,primary cell culture|primary cell culture sample,,,,,,,,,,,,,,,"A cultured cell population comprised of cells expanded directly from living tissue prior to being passaged.

",PERSON:Matthew Brush,,,,,"2013-6-5 MHB: This OBI class was formerly called 'primary cell culture', but label changed and definition updated following CLO alignment work.  Previous definition: 'a primary cell culture is a cell culture where the cells derive from a fresh tissue source.'",primary cultured cell population,,"Spleen cells put directly into culture;  Cold storage of biopsies from wild endangered native Chilean species in field conditions and subsequent isolation of primary culture cell lines. In Vitro Cell Dev Biol Anim. 2008 Jul 2. PMID: 18594934|cells that have been isolated from some organismal source, expanded in culture, but not undergone a complete passaging (ie are still in culture, or have been lifted from culture and frozen in aliquots for future use)",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,http://purl.obolibrary.org/obo/CL_0000001,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0100061,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,primary cultured cell population,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_1000048,transgenic organism,,a transgenic organism is material entity which derives from an organism which has been modified to express a gene not normally part of it,false,,,http://purl.obolibrary.org/obo/OBI_0302859,,,,,,,,,,,,,,,,,,,a transgenic organism is material entity which derives from an organism which has been modified to express a gene not normally part of it,GROUP:IEDB,,,,,PRS:22-02-2008: is a organism which has output_role during genetic modification of type (KO) protocol-application,transgenic organism,,"HLA-A*0201 transgenic mice, Vaccinia virus expressing the LCMV gp protein
Possible ecological risks of transgenic organism release when transgenes affect mating success: sexual selection and the Trojan gene hypothesis. Proc Natl Acad Sci U S A. 1999 Nov 23;96(24):13853-6. PMID: 10570162",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1000048,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0600043,,,transgenic organism,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters|PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0002077,specimens derived from shared ancestor,specimen family,A collection of specimens derived from one common specimen via one or more material processing process(es).,false,,,http://purl.obolibrary.org/obo/OBI_0002076,,,,specimen family,,,,,,,,,,,,,,,A collection of specimens derived from one common specimen via one or more material processing process(es).,"Helena Ellis, Anna Maria Masci, OBIB, OBI",,,,,Details see tracker: https://sourceforge.net/p/obi/obi-terms/778/,specimens derived from shared ancestor,,Aliquoting one specimen to multiple tubes and the collection of the aliquoted specimens are a specimen family. Slicing a tissue specimen into multiple sections for microscopy.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002077,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,specimens derived from shared ancestor,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Biobank,,,,,,,,"Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001787,cytometric bead array assay measuring epitope specific vascular endothelial growth factor production by T cells,VEGF release|cytometric bead array,An assay of epitope specific vascular endothelial growth factor production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001570,,,,,,,,,,,,,,,,,,,An assay of epitope specific vascular endothelial growth factor production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific vascular endothelial growth factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001787,,,,,,,,,,,,,,,,,,,,,,,,VEGF release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific vascular endothelial growth factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001619,specimen collection time measurement datum,collection date|Specimen Collection Date,A time measurement datum that is the measure of the time when the specimens are collected.,false,,,http://purl.obolibrary.org/obo/IAO_0000416,,,,collection date,,,,,,,,,,,,,,,A time measurement datum that is the measure of the time when the specimens are collected.,NIAID GSCID-BRC metadata working group,,,,,,specimen collection time measurement datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001619,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,specimen collection time measurement datum,,,,,,Specimen Collection Date,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000659,specimen collection process,specimen collection,A planned process with the objective of collecting a specimen.,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,specimen collection,,,,,,,,,,,,,"5/31/2012: This process is not necessarily an acquisition, as specimens may be collected from materials already in posession|6/9/09: used at workshop",,A planned process with the objective of collecting a specimen.,,,,,,"label  changed to 'specimen collection process' on 10/27/2014, details see tracker:
http://sourceforge.net/p/obi/obi-terms/716/|Philly2013: A specimen collection can have as part a material entity acquisition, such as ordering from a bank. The distinction is that specimen collection necessarily involves the creation of a specimen role. However ordering cell lines cells from ATCC for use in an investigation is NOT a specimen collection, because the cell lines already have a specimen role.|Philly2013: The specimen_role for the specimen is created during the specimen collection process.|Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation.",specimen collection process,,"drawing blood from a patient for analysis, collecting a piece of a plant for depositing in a herbarium, buying meat from a butcher in order to measure its protein content in an investigation",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000040,http://purl.obolibrary.org/obo/OBI_0100051,,,OBI:0000659,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,specimen collection process,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_1110177,intracellular cytokine staining assay measuring epitope specific interleukin-10 production by T cells,IL-10 release|ICS,An assay of epitope specific interleukin-10 production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001209,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-10 production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-10 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110177,,,,,,,,,,,,,,,,,,,,,,,,IL-10 release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-10 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0200111,data visualization,visualization|data encoding as image,"An planned process that creates images, diagrams or animations from the input data.",false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,visualization|data encoding as image,,,,,,,,,,,,,"Possible future hierarchy might include this:
information_encoding
>data_encoding
>>image_encoding",,"An planned process that creates images, diagrams or animations from the input data.",PERSON: Elisabetta Manduchi|PERSON: James Malone|PERSON: Tina Boussard|PERSON: Melanie Courtot,,,,,,data visualization,,Generation of a heatmap from a microarray dataset,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000027,,,,OBI:0200111,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,data visualization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Tina Boussard|Melanie Courtot|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0000678,portioning objective,,"A material separation objective aiming to separate material into multiple portions, each of which contains a similar composition of the input material.",false,,,http://purl.obolibrary.org/obo/OBI_0000639,,,,,,,,,,,,,,,,,,,"A material separation objective aiming to separate material into multiple portions, each of which contains a similar composition of the input material.",,,,,,,portioning objective,,The objective to obtain multiple aliquots of an enzyme preparation.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000678,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,portioning objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001230,biological activity assay measuring epitope specific interleukin-5 production by T cells,IL-5 release|biological activity,A T cell epitope specific cytokine production assay that detects interleukin-5 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects interleukin-5 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific interleukin-5 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001230,,,,,,,,,,,,,,,,,,,,,,,,IL-5 release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific interleukin-5 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/BFO_0000144,process profile,,b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002]),false,,,http://purl.obolibrary.org/obo/BFO_0000015,,,,,,,ProcessProfile,process-profile,,,,,,,,,,,b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002]),,,,,,,process profile,"b process_profile_of c holds when b proper_occurrent_part_of c& there is some proper_occurrent_part d of c which has no parts in common with b & is mutually dependent on b& is such that b, c and d occupy the same temporal region (axiom label in BFO2 Reference: [094-005])","The simplest type of process profiles are what we shall call ‘quality process profiles’, which are the process profiles which serve as the foci of the sort of selective abstraction that is involved when measurements are made of changes in single qualities, as illustrated, for example, by process profiles of mass, temperature, aortic pressure, and so on.|One important sub-family of rate process profiles is illustrated by the beat or frequency profiles of cyclical processes, illustrated by the 60 beats per minute beating process of John’s heart, or the 120 beats per minute drumming process involved in one of John’s performances in a rock band, and so on. Each such process includes what we shall call a beat process profile instance as part, a subtype of rate process profile in which the salient ratio is not distance covered but rather number of beat cycles per unit of time. Each beat process profile instance instantiates the determinable universal beat process profile. But it also instantiates multiple more specialized universals at lower levels of generality, selected from   rate process profilebeat process profileregular beat process profile3 bpm beat process profile4 bpm beat process profileirregular beat process profileincreasing beat process profileand so on.In the case of a regular beat process profile, a rate can be assigned in the simplest possible fashion by dividing the number of cycles by the length of the temporal region occupied by the beating process profile as a whole. Irregular process profiles of this sort, for example as identified in the clinic, or in the readings on an aircraft instrument panel, are often of diagnostic significance.|On a somewhat higher level of complexity are what we shall call rate process profiles, which are the targets of selective abstraction focused not on determinate quality magnitudes plotted over time, but rather on certain ratios between these magnitudes and elapsed times. A speed process profile, for example, is represented by a graph plotting against time the ratio of distance covered per unit of time. Since rates may change, and since such changes, too, may have rates of change, we have to deal here with a hierarchy of process profile universals at successive levels",,,,,,,,(forall (x y) (if (processProfileOf x y) (and (properContinuantPartOf x y) (exists (z t) (and (properOccurrentPartOf z y) (TemporalRegion t) (occupiesSpatioTemporalRegion x t) (occupiesSpatioTemporalRegion y t) (occupiesSpatioTemporalRegion z t) (not (exists (w) (and (occurrentPartOf w x) (occurrentPartOf w z))))))))) // axiom label in BFO2 CLIF: [094-005] |(iff (ProcessProfile a) (exists (b) (and (Process b) (processProfileOf a b)))) // axiom label in BFO2 CLIF: [093-002] ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000144,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,process profile,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000075,diagnosis textual entity,,"diagnosis is an assessment of a disease or injury, its likely prognosis and treatment.",false,,,http://purl.obolibrary.org/obo/IAO_0000300,,,,,,,,,,,,,,,,,,,"diagnosis is an assessment of a disease or injury, its likely prognosis and treatment.",,,,,,,diagnosis textual entity,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000075,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,diagnosis textual entity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0600051,gradient separation,,a protocol application that uses different concentrations of materials in a defined order to create a gradient to facilitate the separation of an input material into its components with specific qualities,false,,,http://purl.obolibrary.org/obo/OBI_0600014,,http://purl.obolibrary.org/obo/OBI_0000681,,,,,,,,,,,,,,,,,a protocol application that uses different concentrations of materials in a defined order to create a gradient to facilitate the separation of an input material into its components with specific qualities,OBI branch derived,,,,,,gradient separation,,the use of a sucrose gradient to isolate mitochondria,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600051,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,gradient separation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Kevin Clancy,,
http://purl.obolibrary.org/obo/OBI_0000875,viral hemagglutination inhibition assay,,"An assay that measures the ability of an evaluant to inhibit hemagglutination by a virus. Hemagglutinin is a viral protein which binds to sialic acid receptors on cells or to erythrocytes, causing the cells to clump. Loss of clumping indicates hemagglutination inhibition by the antibody.",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,"An assay that measures the ability of an evaluant to inhibit hemagglutination by a virus. Hemagglutinin is a viral protein which binds to sialic acid receptors on cells or to erythrocytes, causing the cells to clump. Loss of clumping indicates hemagglutination inhibition by the antibody.",Bjoern and Melanie,,,,,,viral hemagglutination inhibition assay,,Examining the ability of a monoclonal antibody to inhibit hemagglutination by Influenza A virus by comparing the levels of hemagglutination with and without the presence of the antibody.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000875,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,viral hemagglutination inhibition assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern and Melanie,,
http://purl.obolibrary.org/obo/OBI_0001808,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-3 production by T cells,IL-3 release|RNA/DNA detection,An assay of epitope specific interleukin-3 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001406,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-3 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-3 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001808,,,,,,,,,,,,,,,,,,,,,,,,IL-3 release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-3 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000986,obsolete_DNA sequencing training service,,A training process with the objective to provide a trainee with the skill to run DNA sequencing experiments,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,A training process with the objective to provide a trainee with the skill to run DNA sequencing experiments,,,,,,03/22/2010:workshop: there is a user requirement that not in all cases of the training the trainee gains the skills.,obsolete_DNA sequencing training service,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,OBI:0000986,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_DNA sequencing training service,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/IAO_0000007,action specification,,a directive information entity that describes an action the bearer will take,false,,,http://purl.obolibrary.org/obo/IAO_0000033,,,,,,,,,,,,,,,,,,,a directive information entity that describes an action the bearer will take,OBI Plan and Planned Process branch,,,,,,action specification,,Pour the contents of flask 1 into flask 2,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000007,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,action specification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0001625,sequence annotation algorithm,Annotation Algorithm,An algorithm used to identify sequence features (e.g. protein coding regions) in the assembled contig sequence.  This may also include a description of any manual curation that may have generated or validated the annotation.,false,,,http://purl.obolibrary.org/obo/IAO_0000064,,,,,,,,,,,,,,,,,,,An algorithm used to identify sequence features (e.g. protein coding regions) in the assembled contig sequence.  This may also include a description of any manual curation that may have generated or validated the annotation.,NIAID GSCID-BRC metadata working group,,,,,,sequence annotation algorithm,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001625,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sequence annotation algorithm,,,,,,Annotation Algorithm,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000995,administration of material to specimen,,The directed combination of a material entity with a specimen.,false,,,http://purl.obolibrary.org/obo/OBI_0000274,,,,,,,,,,,,,,,,,,,The directed combination of a material entity with a specimen.,Bjoern Peters,,,,,,administration of material to specimen,,Staining cells in a tissue slice with a dye. ,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000995,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,administration of material to specimen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000153,cell co-culturing,,A material combination in which cell cultures of two or more different types are are combined and allowed to culture as one.,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,A material combination in which cell cultures of two or more different types are are combined and allowed to culture as one.,OBI branch derived,,,,,,cell co-culturing,,Culturing  cytotoxic T-lymphocytes together with target cells in order to study lysis of the target cells. See chromium_release_assay,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000079,http://purl.obolibrary.org/obo/OBI_0100060,,,OBI:0000153,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cell co-culturing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/BFO_0000019,quality,,,false,,,http://purl.obolibrary.org/obo/BFO_0000020,,,,,,,Quality,quality,,,,,,,,,,,,,,,,,,quality,"a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])",the color of a tomato|the ambient temperature of this portion of air|the length of the circumference of your waist|the mass of this piece of gold.|the shape of your nostril|the shape of your nose,,,,,,,,(forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] |(forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] ,"If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000019,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,quality,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000574,high temperature column,,A high temperature column is a chromatography column which is suitable for and withstands very high temperatures in chromatography ovens.,false,,,http://purl.obolibrary.org/obo/OBI_0000038,,,,,,,,,,,,,,,,,,,A high temperature column is a chromatography column which is suitable for and withstands very high temperatures in chromatography ovens.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01233,,,,,,high temperature column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000574,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,high temperature column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000868,pattern matching objective,,"A pattern matching objective aims to detect the presence of the constituents of a given pattern. In contrast to pattern recognition, the pattern is rigidly specified. Patterns are typicall sequences or trees.",false,,,http://purl.obolibrary.org/obo/OBI_0200166,,,,,,,,,,,,,,,,,,,"A pattern matching objective aims to detect the presence of the constituents of a given pattern. In contrast to pattern recognition, the pattern is rigidly specified. Patterns are typicall sequences or trees.",http://en.wikipedia.org/wiki/Pattern_matching,,,,,,pattern matching objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000868,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,pattern matching objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Tina Boussard,,
http://purl.obolibrary.org/obo/OBI_0000144,role of independent data monitoring committee,independent data monitoring committee,"a trial monitor role charged recommending whether to continue, modify, or end the trial",false,,,http://purl.obolibrary.org/obo/OBI_0000060,,,,independent data monitoring committee,,,,,,,,,,,,,,,"a trial monitor role charged recommending whether to continue, modify, or end the trial",,,,,,,role of independent data monitoring committee,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000144,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,role of independent data monitoring committee,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0001344,ELISA measuring epitope specific monocyte chemotactic protein-1 production by T cells,CCL2/MCP-1 release|ELISA,An assay of epitope specific monocyte chemotactic protein-1 production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001465,,,,,,,,,,,,,,,,,,,An assay of epitope specific monocyte chemotactic protein-1 production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific monocyte chemotactic protein-1 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001344,,,,,,,,,,,,,,,,,,,,,,,,CCL2/MCP-1 release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific monocyte chemotactic protein-1 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0200147,network graph quality calculation,,A network analysis in which an input data set describing node objects and edge relationships between node objects is used to determine the output quality of the network as a whole.,false,,,http://purl.obolibrary.org/obo/OBI_0200080,,,,,,,,,,,,,,,,,,,A network analysis in which an input data set describing node objects and edge relationships between node objects is used to determine the output quality of the network as a whole.,PERSON: Richard Scheuermann,,,,,,network graph quality calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200147,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,network graph quality calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Richard Scheuermann,,
http://purl.obolibrary.org/obo/OBI_0001884,specimen-based scope of investigation specification,Sample Scope,A plan specification which specifies the scope of an investigation based on the heterogeneity of organisms or type of material that are the specified input of specimen collection.,false,,,http://purl.obolibrary.org/obo/IAO_0000104,,,,,,,,,,,,,,,,,,,A plan specification which specifies the scope of an investigation based on the heterogeneity of organisms or type of material that are the specified input of specimen collection.,NIAID GSCID-BRC metadata working group,,,,,,specimen-based scope of investigation specification,,"Some examples of specimen scope are Monoisolate, Multiisolate, Multi-species, Environment, or Synthetic.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0500000,OBI:0001884,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,specimen-based scope of investigation specification,,,,,,Sample Scope,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001271,RNA-seq assay,transcription profiling by high throughput sequencing,"An assay in which sequencing technology (e.g. Solexa/454) is used to generate RNA sequence, analyse the transcibed regions of the genome, and or to quantitate transcript abundance",false,,,http://purl.obolibrary.org/obo/OBI_0600047|http://purl.obolibrary.org/obo/OBI_0000424,,http://purl.obolibrary.org/obo/OBI_0001331,,transcription profiling by high throughput sequencing,,,,,,,,,,,,,"JZ: should be inferred as 'DNA sequencing'. Will check in the future.|an assay that uses high-throughput sequencing technologies to sequence cDNA in order to get information about a sample's RNA content. RNA-Seq provides researchers with efficient ways to measure transcriptome data experimentally, allowing them to get information such as how different alleles of a gene are expressed, detect post-transcriptional mutations or identify gene fusions.

WEB: http://en.wikipedia.org/wiki/RNA-Seq",,"An assay in which sequencing technology (e.g. Solexa/454) is used to generate RNA sequence, analyse the transcibed regions of the genome, and or to quantitate transcript abundance",EFO_0002770 transcription profiling by high throughput sequencing,,,,,,RNA-seq assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0400103,,,,,,,,,,,,,,,OBI:0001271,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,RNA-seq assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: James Malone,,
http://purl.obolibrary.org/obo/OBI_0200115,pearson correlation coefficient calculation,,"A pearson correlation coefficient calculation is a similarity calculation which attaches to each pair of random variables X and Y the ratio of their covariance by the product of their standard deviations. Given a series of n measurements of X and Y written as x_i and y_i where i = 1, 2, ..., n, then their Pearson correlation coefficient refers to the ""sample correlation coefficient"" and is written as the sum over i of the ratios (x_i-xbar)*(y_i-ybar)/((n-1)*s_x*s_y) where xbar and ybar are the sample means of X and Y , s_x and s_y are the sample standard deviations of X and Y. The closer the pearson correlation coefficient is to 1, the more similar the inputs are considered.",false,,,http://purl.obolibrary.org/obo/OBI_0200113,,,,,,,,,,,,,,,,,,,"A pearson correlation coefficient calculation is a similarity calculation which attaches to each pair of random variables X and Y the ratio of their covariance by the product of their standard deviations. Given a series of n measurements of X and Y written as x_i and y_i where i = 1, 2, ..., n, then their Pearson correlation coefficient refers to the ""sample correlation coefficient"" and is written as the sum over i of the ratios (x_i-xbar)*(y_i-ybar)/((n-1)*s_x*s_y) where xbar and ybar are the sample means of X and Y , s_x and s_y are the sample standard deviations of X and Y. The closer the pearson correlation coefficient is to 1, the more similar the inputs are considered.",PERSON: Elisabetta Manduchi|WEB: http://en.wikipedia.org/wiki/Correlation,,,,,,pearson correlation coefficient calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200115,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,pearson correlation coefficient calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0001075,hybridization oven,,A device that creates an appropriate environment for nucleic acid hybridization.,false,,,http://purl.obolibrary.org/obo/OBI_0000967|http://purl.obolibrary.org/obo/OBI_0000136,,,,,,,,,,,,,,,,,,,A device that creates an appropriate environment for nucleic acid hybridization.,PERSON: Erik Segerdell,,,,,,hybridization oven,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000370|http://purl.obolibrary.org/obo/OBI_0000379,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001075,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,hybridization oven,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0000954,subcutaneous injection,,is the injection of a material entity (bearing the administered substance role) into the hypodermis (bearing the target role) of an organism using a syringe,false,,,http://purl.obolibrary.org/obo/OBI_0000426|http://purl.obolibrary.org/obo/OBI_0600007,,http://purl.obolibrary.org/obo/OBI_0000434,,,,,,,,,,,,,,,,,is the injection of a material entity (bearing the administered substance role) into the hypodermis (bearing the target role) of an organism using a syringe,,,,,,,subcutaneous injection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000954,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,subcutaneous injection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0000688,rodent care protocol,,A rodent care protocol is an animal protocol in which the animals being taken care of are rodents.,false,,,http://purl.obolibrary.org/obo/OBI_0000715,,,,,,,,,,,,,,,,,,,A rodent care protocol is an animal protocol in which the animals being taken care of are rodents.,Bjoern Peters,,,,,,rodent care protocol,,"Keeping mice in the UCSD animals facility at 20 - 25 degrees celsius, in cages of 4 animals each and providing food twice daily.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000688,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,rodent care protocol,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000374,excitation function,,"A excitation function is a function  to inject energy by bombarding a material with energetic particles (e.g., photons) thereby imbuing internal material components such as electrons with additional energy.  These internal, 'excited' particles may lead to the rupturing of covalent chemical bonds or may quickly relax back to there unexcited state with an exponential time course thereby locally emitting energy in the form of photons.",false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,"A excitation function is a function  to inject energy by bombarding a material with energetic particles (e.g., photons) thereby imbuing internal material components such as electrons with additional energy.  These internal, 'excited' particles may lead to the rupturing of covalent chemical bonds or may quickly relax back to there unexcited state with an exponential time course thereby locally emitting energy in the form of photons.",,,,,,,excitation function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000374,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,excitation function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bill Bug|Daniel Schober|Frank Gibson|Melanie Courtot,,
http://purl.obolibrary.org/obo/GO_0035393,chemokine (C-X-C motif) ligand 9 production,,"The appearance of chemokine (C-X-C motif) ligand 9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0032602,,,,,,,,,,,,,,,,,,,"The appearance of chemokine (C-X-C motif) ligand 9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,chemokine (C-X-C motif) ligand 9 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0035393,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,chemokine (C-X-C motif) ligand 9 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0035397,helper T cell enhancement of adaptive immune response,,Positive regulation of an adaptive immune response mediated via cytokine production by helper T cell.,false,,,http://purl.obolibrary.org/obo/GO_0002250,,,,,,,,,,,,,,,,,,,Positive regulation of an adaptive immune response mediated via cytokine production by helper T cell.,,,,,,,helper T cell enhancement of adaptive immune response,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0035397,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,helper T cell enhancement of adaptive immune response,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0035399,helper T cell enhancement of B cell mediated immune response,,Positive regulation of a B cell mediated immune response mediated via cytokine production by a helper T cell.,false,,,http://purl.obolibrary.org/obo/GO_0035397,,,,,,,,,,,,,,,,,,,Positive regulation of a B cell mediated immune response mediated via cytokine production by a helper T cell.,,,,,,,helper T cell enhancement of B cell mediated immune response,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0035399,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,helper T cell enhancement of B cell mediated immune response,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0035398,helper T cell enhancement of T cell mediated immune response,,Positive regulation of a T cell mediated immune response mediated via cytokine production by a helper T cell.,false,,,http://purl.obolibrary.org/obo/GO_0035397,,,,,,,,,,,,,,,,,,,Positive regulation of a T cell mediated immune response mediated via cytokine production by a helper T cell.,,,,,,,helper T cell enhancement of T cell mediated immune response,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0035398,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,helper T cell enhancement of T cell mediated immune response,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000073,sample preparation for assay,study,A sample_preparation_for_assay is a protocol_application including material_enrollments and biomaterial_transformations. definition_source: OBI.,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,study,,,,,,,,,,,,,,,A sample_preparation_for_assay is a protocol_application including material_enrollments and biomaterial_transformations. definition_source: OBI.,OBI branch derived,,,,,,sample preparation for assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000073,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sample preparation for assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/IAO_0000310,document,,A collection of information content entities intended to be understood together as a whole,false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,,,,,,,,,,,,,,,,A collection of information content entities intended to be understood together as a whole,,,,,,,document,,"A journal article, patent application, laboratory notebook, or a book",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000310,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,document,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0001849,structural analysis by paired-end tag sequencing,DNA-PET assay|DNA-PET,An assay that incorporates Paired-End Tags and sequencing technology to determine structural variants.,false,,,http://purl.obolibrary.org/obo/OBI_0000626,,http://purl.obolibrary.org/obo/OBI_0000113,,DNA-PET assay|DNA-PET,,,,,,,,,,,,,,,An assay that incorporates Paired-End Tags and sequencing technology to determine structural variants.,"Yao, et al. Long Span DNA Paired-End-Tag (DNA-PET) Sequencing Strategy for the Interrogation of Genomic Structural Mutations and Fusion-Point-Guided Reconstruction of Amplicons. PLoS One. 2012;7(9):e46152 [PMID:23029419]",,,,,,structural analysis by paired-end tag sequencing,,"Yao, et al. Long Span DNA Paired-End-Tag (DNA-PET) Sequencing Strategy for the Interrogation of Genomic Structural Mutations and Fusion-Point-Guided Reconstruction of Amplicons. PLoS One. 2012;7(9):e46152 [PMID:23029419]",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001852|http://purl.obolibrary.org/obo/OBI_0000626,http://purl.obolibrary.org/obo/OBI_0400103,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001573,,,OBI:0001849,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,structural analysis by paired-end tag sequencing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001453,intracellular cytokine staining assay measuring epitope specific lymphotoxin A production by T cells,lymphotoxin A/TNFb release|ICS,An assay of epitope specific lymphotoxin A production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001385|http://purl.obolibrary.org/obo/OBI_0001327,,,,,,,,,,,,,,,,,,,An assay of epitope specific lymphotoxin A production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific lymphotoxin A production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001453,,,,,,,,,,,,,,,,,,,,,,,,lymphotoxin A/TNFb release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific lymphotoxin A production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0200126,network graph construction,,A network analysis in which an input data set describing objects and relationships between objects is transformed into an output representation of these objects as nodes and the relationships as edges of a network graph.,false,,,http://purl.obolibrary.org/obo/OBI_0200080,,,,,,,,,,,,,,,,,,,A network analysis in which an input data set describing objects and relationships between objects is transformed into an output representation of these objects as nodes and the relationships as edges of a network graph.,PERSON: Richard Scheuermann,,,,,,network graph construction,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200126,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,network graph construction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Richard Scheuermann,,
http://purl.obolibrary.org/obo/IAO_0000579,centrally registered identifier registry,CRID registry,"A CRID registry is a dataset of CRID records, each consisting of a CRID symbol and additional information which was recorded in the dataset through a assigning a centrally registered identifier process.",false,,,http://purl.obolibrary.org/obo/IAO_0000100,,,,CRID registry,,,,,,,,,,,,,,,"A CRID registry is a dataset of CRID records, each consisting of a CRID symbol and additional information which was recorded in the dataset through a assigning a centrally registered identifier process.","Original proposal from Bjoern, discussions at IAO calls",,,,,,centrally registered identifier registry,,PubMed is a CRID registry. It has a dataset of PubMed identifiers associated with journal articles. ,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000579,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,centrally registered identifier registry,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters|PERSON: Melanie Courtot|PERSON: Bill Hogan|PERSON: Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0001829,ELISPOT assay measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells,CCL1/TCA-3 release|ELISPOT,An assay of epitope specific chemokine (C-C motif) ligand 1 production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001276,,,,,,,,,,,,,,,,,,,An assay of epitope specific chemokine (C-C motif) ligand 1 production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001829,,,,,,,,,,,,,,,,,,,,,,,,CCL1/TCA-3 release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_1110131,biological activity assay measuring epitope specific proliferation of T cells,proliferation|biological activity,A T cell epitope dependent biological activity assay that detects T cell proliferation.,false,,,http://purl.obolibrary.org/obo/OBI_0002055,,,,,,,,,,,,,,,,,,,A T cell epitope dependent biological activity assay that detects T cell proliferation.,IEDB,,,,,,biological activity assay measuring epitope specific proliferation of T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110131,,,,,,,,,,,,,,,,,,,,,,,,proliferation|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific proliferation of T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001903,email address of specimen provider principal investigator,Sample Provider PI's email,An email address of the principal investigator providing the specimens for the investigation,false,,,http://purl.obolibrary.org/obo/IAO_0000429,,,,,,,,,,,,,,,,,,,An email address of the principal investigator providing the specimens for the investigation,NIAID GSCID-BRC metadata working group,,,,,,email address of specimen provider principal investigator,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001903,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,email address of specimen provider principal investigator,,,,,,Sample Provider PI's email,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001131,slide warmer,,A device that is used to heat microscope slides.,false,,,http://purl.obolibrary.org/obo/OBI_0001034,,,,,,,,,,,,,,,,,,,A device that is used to heat microscope slides.,PERSON: Erik Segerdell,,,,,,slide warmer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000371,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001131,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,slide warmer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001963,target subfragment specification,target subfragment,"is a directive information specifying a genomic region, possibly located in a coding genomic region, which is the focus of a planned process such as an assay, for instance in a environmental gene survey",false,,,http://purl.obolibrary.org/obo/IAO_0000033,,,,,,,,,,,,,,,,,,,"is a directive information specifying a genomic region, possibly located in a coding genomic region, which is the focus of a planned process such as an assay, for instance in a environmental gene survey",PRS for OBI,,,,,,target subfragment specification,,"http://www.ncbi.nlm.nih.gov/pubmed/23335919

""performing a profiling of microbial phylogenetic composition using massively-parallel pyrotag sequencing targeting the V9 hypervariable region (used as target subfragment) of the 18S ribosomal RNA (rRNA) gene (used as target gene)",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001963,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,target subfragment,target subfragment specification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001201,epitope specific tolerance induction by T cells,,A process of tolerance induction by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0002507,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of tolerance induction by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific tolerance induction by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001201,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific tolerance induction by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000813,to be treated with active ingredient role,,"A study subject role which begins to exist when a subject is assigned to be one of those who will receive active ingredient, and is realized in a study execution in which they receive the active ingredient",false,,,http://purl.obolibrary.org/obo/OBI_0000097,,,,,,,,,,,,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,,"A study subject role which begins to exist when a subject is assigned to be one of those who will receive active ingredient, and is realized in a study execution in which they receive the active ingredient",PERSON: Helen Parkinson,,,,,,to be treated with active ingredient role,,Role of a patient in a group treated with an active substance in a clinical trial,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000813,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,to be treated with active ingredient role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/GO_0005575,cellular_component,,"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.",false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.",,,,,,,cellular_component,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0005575,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,cellular_component,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/REO_0000171,molecular label role,molecular tracer role,"a reagent role inhering in a molecular entity intended to associate with some molecular target to serve as a proxy for the presence, abundance, or location of this target in a detection of molecular label assay.",false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,molecular tracer role,,,,,,,,,,,,,,,"a reagent role inhering in a molecular entity intended to associate with some molecular target to serve as a proxy for the presence, abundance, or location of this target in a detection of molecular label assay.","OBI developer call, 3-12-12",,,,,MHB (9-29-13): 'molecular label role' imported from the Reagent Ontology and replaced OBI:OBI_0000140 (label role),molecular label role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,REO:0000171,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/reo.owl,,,,,,,,,,,,,,,,,,,molecular label role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0400042,FC 500,,"A FC_500 is a flow_cytometer_analyser manufactured by Beckman Coulter. It features digital electronics, 488 nm and 635 nm lasers, filters and PMTs for 5 fluorescent parameters, a diode for collecting side scatter and a solid state detector for forward scatter. The FC 500 is an analyser usually used for either research or clinical applications.",false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,,,,,,,,,,,,,,,,"A FC_500 is a flow_cytometer_analyser manufactured by Beckman Coulter. It features digital electronics, 488 nm and 635 nm lasers, filters and PMTs for 5 fluorescent parameters, a diode for collecting side scatter and a solid state detector for forward scatter. The FC 500 is an analyser usually used for either research or clinical applications.",http://www.beckmancoulter.com/products/instrument/flowcytometry/fc500series.asp,,,,,,FC 500,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400042,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,FC 500,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0000654,device setting,,a quality inheres_in some device and is concretization of some (device_setting_specification and is_about a quality of the device,false,,,http://purl.obolibrary.org/obo/BFO_0000019,,,,,,,,,,,,,,,,,,,a quality inheres_in some device and is concretization of some (device_setting_specification and is_about a quality of the device,,,,,,,device setting,,"Examples, 300V for 4 hours, 200mvolts, 37degrees.A knob set a 300 V is the device setting, the protocol stating to set the instrument to 300V is a device setting specification",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000654,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,,,,,,,,,,,,,,device setting,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Frank Gibson,,
http://purl.obolibrary.org/obo/OBI_0000612,Bruker MATCH tube holder system,Bruker Multiple Adjustable Tube Clamp Holder,"The Bruker Multiple Adjustable Tube Clamp Holder MATCH system is a holder for 100 mm long NMR sample tubes with diameters ranging from micro tubes up to 5 mm NMR tubes. The MATCH insert fits into a standard 10 mm Bruker spinner and is suitable for all non-spinning applications.\n   The MATCH system provides an easy and cost efficient means of optimizing the signal-to-noise ratio of each sample. By matching the NMR tube diameter to the size of the sample, most of the sample can be placed in the active column of the NMR coil. This leads to an enhanced signal detection compared to diluting the same sample quantity in a larger tube.",false,,,http://purl.obolibrary.org/obo/OBI_0000484,,,,Bruker Multiple Adjustable Tube Clamp Holder,,,,,,,,,,,,,NMR instrument,,"The Bruker Multiple Adjustable Tube Clamp Holder MATCH system is a holder for 100 mm long NMR sample tubes with diameters ranging from micro tubes up to 5 mm NMR tubes. The MATCH insert fits into a standard 10 mm Bruker spinner and is suitable for all non-spinning applications.\n   The MATCH system provides an easy and cost efficient means of optimizing the signal-to-noise ratio of each sample. By matching the NMR tube diameter to the size of the sample, most of the sample can be placed in the active column of the NMR coil. This leads to an enhanced signal detection compared to diluting the same sample quantity in a larger tube.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400211,,,,,,Bruker MATCH tube holder system,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000612,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker MATCH tube holder system,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0302716,pool of specimens,,"A pool of specimens is a mixture of a population of samples which have been gathered from one or more sample populations, obtained by the physical process of mixing individual specimens, e.g.  mixing the DNA collected from the individual fish.",false,,,http://purl.obolibrary.org/obo/OBI_0100051|http://purl.obolibrary.org/obo/OBI_0000953,,,,,,,,,,,,,,,,,,,"A pool of specimens is a mixture of a population of samples which have been gathered from one or more sample populations, obtained by the physical process of mixing individual specimens, e.g.  mixing the DNA collected from the individual fish.",GROUP: CEBS,,,,,"check with advisors as to how to represent multiple instances of any class? a set of specimens which have been gathered from one or more sample_populations, obtained by the physical process of mixing individual specimens, e.g.  mixing the DNA collected from the individual fish",pool of specimens,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302716,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,pool of specimens,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0200154,agglomerative hierarchical clustering,bottom-up hierarchical clustering,An agglomerative hierarchical clustering is a hierarchical clustering which starts with separate clusters and then successively combines these clusters until there is only one cluster remaining.,false,,,http://purl.obolibrary.org/obo/OBI_0200042,,,,bottom-up hierarchical clustering,,,,,,,,,,,,,,,An agglomerative hierarchical clustering is a hierarchical clustering which starts with separate clusters and then successively combines these clusters until there is only one cluster remaining.,PERSON: Elisabetta Manduchi,,,,,,agglomerative hierarchical clustering,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200154,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,agglomerative hierarchical clustering,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0001465,biological activity assay measuring epitope specific monocyte chemotactic protein-1 production by T cells,CCL2/MCP-1 release|biological activity,A T cell epitope specific cytokine production assay that detects monocyte chemotactic protein-1 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects monocyte chemotactic protein-1 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific monocyte chemotactic protein-1 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001465,,,,,,,,,,,,,,,,,,,,,,,,CCL2/MCP-1 release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific monocyte chemotactic protein-1 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_1110118,P815 cell line,,A cell line derived from mouse mastocytoma.,false,,,http://purl.obolibrary.org/obo/CLO_0009828,,,,,,,,,,,,,,,,,,,A cell line derived from mouse mastocytoma.,IEDB|http://www.biotech.ist.unige.it/cldb/cl5244.html,,,,,,P815 cell line,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110118,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,P815 cell line,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000795,glucometer,glucose meter,A measurement device with the function to measure and record the level/amount of glucose in a blood sample,false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,glucose meter,,,,,,,,,,,,,,,A measurement device with the function to measure and record the level/amount of glucose in a blood sample,http://en.wikipedia.org/wiki/Glucose_meter,,,,,,glucometer,,Diabetic patients use glucometers to determine their glucose levels,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000795,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,glucometer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Frank Gibson|PERSON:Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0001283,ELISA measuring epitope specific interleukin-15 production by T cells,IL-15 release|ELISA,An assay of epitope specific interleukin-15 production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001292,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-15 production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific interleukin-15 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001283,,,,,,,,,,,,,,,,,,,,,,,,IL-15 release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific interleukin-15 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_1110052,cultured CD4-/CD8- T cell population,CD4-/CD8- T cell culture sample,A T cell population characterized by not expressing the CD4 nor the CD8 molecule on its surface.,false,,,http://purl.obolibrary.org/obo/OBI_1110050|http://purl.obolibrary.org/obo/OBI_0001875|http://purl.obolibrary.org/obo/OBI_1110051,,,,CD4-/CD8- T cell culture sample,,,,,,,,,,,,,,,A T cell population characterized by not expressing the CD4 nor the CD8 molecule on its surface.,IEDB,,,,,,cultured CD4-/CD8- T cell population,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110052,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cultured CD4-/CD8- T cell population,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001380,biological activity assay measuring epitope specific interleukin-18 production by T cells,IL-18 release|biological activity,A T cell epitope specific cytokine production assay that detects interleukin-18 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects interleukin-18 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific interleukin-18 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001380,,,,,,,,,,,,,,,,,,,,,,,,IL-18 release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific interleukin-18 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0600058,enzymatic amplification,,the use of enzymes to increase the number of molecules of a biomaterial,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,the use of enzymes to increase the number of molecules of a biomaterial,OBI branch derived,,,,,,enzymatic amplification,,the use of a polymerase chain reaction to amplify a fragment of DNA,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600058,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,enzymatic amplification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Kevin Clancy,,
http://purl.obolibrary.org/obo/IAO_0000324,acknowledgements section,,Part of a publication that is about the contributions of people or institutions other than the authors.,false,,,http://purl.obolibrary.org/obo/IAO_0000314,,,,,,,,,,,,,,,,,,,Part of a publication that is about the contributions of people or institutions other than the authors.,,,,,,,acknowledgements section,,The authors wish to thank Alan Ruttenberg for his constructive comments about an earlier draft of this manuscript,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000324,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,acknowledgements section,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0000801,spike train datum,spike train measurement,A measurement datum which represents information about an ordered series of action potentials in an organism's CNS measured over time.,false,,,http://purl.obolibrary.org/obo/IAO_0000109,,,,spike train measurement,,,,,,,,,,,,,,,A measurement datum which represents information about an ordered series of action potentials in an organism's CNS measured over time.,"Jessica Turner, NIF",,,,,needs more work to see exactly what the data set looks like - HP,spike train datum,,Measurement of temporal regularity of spike train responses in auditory nerve fibers of the green treefrog,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000801,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,spike train datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Helen Parkinson, Alan Ruttenberg",,
http://purl.obolibrary.org/obo/OBI_1110159,ELISA measuring epitope specific interleukin-13 production by T cells,IL-13 release|ELISA,An assay of epitope specific interleukin-13 production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001251,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-13 production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific interleukin-13 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110159,,,,,,,,,,,,,,,,,,,,,,,,IL-13 release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific interleukin-13 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/GO_0009566,fertilization,,The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).,false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).,,,,,,,fertilization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0009566,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,fertilization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001727,RIA measuring the dissociation constant [KD] of a B cell epitope:antibody complex,dissociation constant KD|radio immuno assay (RIA)|nM,A B cell epitope equilibrium dissociation constant (KD) determination assay that uses a radio immuno assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001491|http://purl.obolibrary.org/obo/OBI_0001708,,,,,,,,,,,,,,,,,,,A B cell epitope equilibrium dissociation constant (KD) determination assay that uses a radio immuno assay.,IEDB,,,,,,RIA measuring the dissociation constant [KD] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001727,,,,,,,,,,,,,,,,,,,,,,,,dissociation constant KD|radio immuno assay (RIA)|nM,,,,,,,,,,,,,,,,,,,,,,RIA measuring the dissociation constant [KD] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001716,B cell epitope specific complement-dependent cytotoxicity,,complement-dependent cytotoxicity resulting from antibody binding to epitope,false,,,http://purl.obolibrary.org/obo/GO_0097278,,,,,,,,,,,,,,,,,Date: 2012-05-03; Spreadsheet: BcellAssays.xls; Worksheet: Especific template; Mapping: ebcell_specific_mappings.owl,,complement-dependent cytotoxicity resulting from antibody binding to epitope,IEDB (QTT),,,,,,B cell epitope specific complement-dependent cytotoxicity,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001716,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,B cell epitope specific complement-dependent cytotoxicity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/IAO_0000024,obsolete_unit of measure,,a unit of measure is the quality of some material entity compared to which another quality is some multiple of.,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,a unit of measure is the quality of some material entity compared to which another quality is some multiple of.,"Smith, Ceusters, Ruttenberg, 2000 years of philosophy",,,,,,obsolete_unit of measure,,The length of a ruler.,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,IAO:0000024,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_unit of measure,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0002012,PacBio RS II,Pacific Biosciences RS II,"A DNA sequencer which is manufactured by the Pacific Biosciences corporation. Built upon single molecule real-time sequencing technology, the machine is optimized for generation with long reads and high consensus accuracy.",false,,,http://purl.obolibrary.org/obo/OBI_0400103,,,,Pacific Biosciences RS II,,,,,,,,,,,,,,,"A DNA sequencer which is manufactured by the Pacific Biosciences corporation. Built upon single molecule real-time sequencing technology, the machine is optimized for generation with long reads and high consensus accuracy.",http://www.pacificbiosciences.com/products/,,,,,,PacBio RS II,,"Spaethling, Jennifer M., and James H. Eberwine. ""Single-cell transcriptomics for drug target discovery."" Current opinion in pharmacology (2013). pmid:23725882",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002012,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PacBio RS II,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"PERSON: Venkat Malladi, Chris Stoeckert, Jie Zheng, Alan Ruttenberg",,
http://purl.obolibrary.org/obo/OBI_0001282,translation profiling assay,,"An assay in which surface-bound, translationally competent ribosome complexes are used to generate a translation profile for mRNA, which mRNA may be a single molecular species, or a combination of species, including complex mixtures such as those found in the set of mRNAs isolated from a cell or tissue. One or more components of the surface-bound ribosome complex may be labeled at specific positions to permit analysis of multiple or single molecules for determination of ribosomal conformational changes and translation kinetics. Translation profiles are used as the basis for comparison of an mRNA or set of mRNA species. The translation profile can be used to determine such characteristics as kinetics of initiation, kinetic of elongation, identity of the polypeptide product, and the like. Analysis of translation profiles may be used to determine differential gene expression, optimization of mRNA sequences for expression, screening drug candidates for an effect on translation.",false,,,http://purl.obolibrary.org/obo/OBI_0000443,,http://purl.obolibrary.org/obo/OBI_0000131,,,,,,,,,,,,,,,,,"An assay in which surface-bound, translationally competent ribosome complexes are used to generate a translation profile for mRNA, which mRNA may be a single molecular species, or a combination of species, including complex mixtures such as those found in the set of mRNAs isolated from a cell or tissue. One or more components of the surface-bound ribosome complex may be labeled at specific positions to permit analysis of multiple or single molecules for determination of ribosomal conformational changes and translation kinetics. Translation profiles are used as the basis for comparison of an mRNA or set of mRNA species. The translation profile can be used to determine such characteristics as kinetics of initiation, kinetic of elongation, identity of the polypeptide product, and the like. Analysis of translation profiles may be used to determine differential gene expression, optimization of mRNA sequences for expression, screening drug candidates for an effect on translation.",EFO_0001033 translation profiling,,,,,,translation profiling assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001282,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,translation profiling assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: James Malone,,
http://purl.obolibrary.org/obo/GO_0043227,membrane-bounded organelle,,"Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.",false,,,http://purl.obolibrary.org/obo/GO_0005575,,,,,,,,,,,,,,,,,,,"Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.",,,,,,,membrane-bounded organelle,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0043227,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,membrane-bounded organelle,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001603,binding off rate measurement datum (koff),,A rate measurement datum of how quickly bound complexes disassociate,false,,,http://purl.obolibrary.org/obo/OBI_0001554|http://purl.obolibrary.org/obo/OBI_0001144,,,,,,,,,,,,,,,,,,,A rate measurement datum of how quickly bound complexes disassociate,IEDB,,,,,,binding off rate measurement datum (koff),,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001603,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,binding off rate measurement datum (koff),,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Bjoern Peters, Randi Vita",,
http://purl.obolibrary.org/obo/OBI_0001074,cryofixation device,,A device that is used for the fixation or stabilization of biological materials as the first step in specimen preparation for electron microscopy.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A device that is used for the fixation or stabilization of biological materials as the first step in specimen preparation for electron microscopy.,http://en.wikipedia.org/wiki/Cryofixation,,,,,,cryofixation device,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0001036,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001074,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cryofixation device,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001450,biological activity assay measuring epitope specific interleukin-4 production by T cells,IL-4 release|biological activity,A T cell epitope specific cytokine production assay that detects interleukin-4 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects interleukin-4 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific interleukin-4 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001450,,,,,,,,,,,,,,,,,,,,,,,,IL-4 release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific interleukin-4 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/SO_0000104,polypeptide,polypeptide sequence,A sequence of amino acids linked by peptide bonds which may lack appreciable tertiary structure and may not be liable to irreversible denaturation.,false,,,http://purl.obolibrary.org/obo/SO_0000001,,,,polypeptide sequence,,,,,,,,,,,,,,,A sequence of amino acids linked by peptide bonds which may lack appreciable tertiary structure and may not be liable to irreversible denaturation.,,,,,,,polypeptide,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,SO:0000104,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/so.owl,,,,,,,,,,,,,,,,,,,polypeptide,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_1110202,epitope specific IL-5 release by T cells,,A biological process where T cells produce IL-5 resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/OBI_0001193|http://purl.obolibrary.org/obo/GO_0032634,,,,,,,,,,,,,,,,,,,A biological process where T cells produce IL-5 resulting from the recognition of a T cell epitope.,IEDB,,,,,,epitope specific IL-5 release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110202,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific IL-5 release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000513,DISCOVERY console,,"The Discovery console is a Windows XP Professional-based, integrated console designed especially for Solid-State NMR. The console includes everything needed to interface to any magnet and solids probe - from computer to cables to duplexing network.",false,,,http://purl.obolibrary.org/obo/OBI_0000599,,,,,,,,,,,,,,,,,NMR instrument/NMR console,,"The Discovery console is a Windows XP Professional-based, integrated console designed especially for Solid-State NMR. The console includes everything needed to interface to any magnet and solids probe - from computer to cables to duplexing network.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400247,,,,,,DISCOVERY console,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000513,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DISCOVERY console,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0200140,mathematical feature,,"feature is a (parent_class) that describes a characteristic, trait or quality of a data transformation",false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,"feature is a (parent_class) that describes a characteristic, trait or quality of a data transformation",PERSON: James Malone,,,,,This class is temporary and will be placed outside of data transformation ultimately (if it still remains at all after review),mathematical feature,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,mathematical feature,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0000118,gene list,,A data set of the names or identifiers of genes that are the outcome of an analysis or have been put together for the purpose of an analysis.,false,,,http://purl.obolibrary.org/obo/IAO_0000100,,,,,,,,,,,,,,,,,"kind of report. (alan) need to be careful to distinguish from output of a data transformation or calculation. A gene list is a report when it is published as such? Relates to question of whether report is a whole, or whether it can be a part of some other narrative object.",,A data set of the names or identifiers of genes that are the outcome of an analysis or have been put together for the purpose of an analysis.,group:OBI,,,,,,gene list,,"Gene lists may arise from analysis to determine differentially expressed genes, may be collected from the literature for involvement in a particular process or pathway (e.g., inflammation), or may be the input for gene set enrichment analysis.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000118,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,gene list,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0001682,bacterial one-hybrid ,B1H," is a method for identifying the sequence-specific target site of a DNA-binding domain. In this system, a given transcription factor (TF) is expressed as a fusion to a subunit of RNA polymerase. In parallel, a library of randomized oligonucleotides representing potential TF target sequences, is cloned into a separate vector containing the selectable genes HIS3 and URA3. If the DNA-binding domain (bait) binds a potential DNA target site (prey) in vivo, it will recruit RNA polymerase to the promoter and activate transcription of the reporter genes in that clone. The two reporter genes, HIS3 and URA3, allow for positive and negative selections, respectively. At the end of the process, positive clones are sequenced and examined with motif-finding tools in order to resolve the favoured DNA target sequence",false,,,http://purl.obolibrary.org/obo/OBI_0000070|http://purl.obolibrary.org/obo/OBI_0001681,,,,B1H,,,,,,,,,,,,,add regulatory region DNA binding;obo:GO:0000975;,," is a method for identifying the sequence-specific target site of a DNA-binding domain. In this system, a given transcription factor (TF) is expressed as a fusion to a subunit of RNA polymerase. In parallel, a library of randomized oligonucleotides representing potential TF target sequences, is cloned into a separate vector containing the selectable genes HIS3 and URA3. If the DNA-binding domain (bait) binds a potential DNA target site (prey) in vivo, it will recruit RNA polymerase to the promoter and activate transcription of the reporter genes in that clone. The two reporter genes, HIS3 and URA3, allow for positive and negative selections, respectively. At the end of the process, positive clones are sequenced and examined with motif-finding tools in order to resolve the favoured DNA target sequence",http://en.wikipedia.org/wiki/Bacterial_one-hybrid_system,,,,,,bacterial one-hybrid ,,"A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system.
Noyes MB, Meng X, Wakabayashi A, Sinha S, Brodsky MH, Wolfe SA.
Nucleic Acids Res. 2008 May;36(8):2547-60. Epub 2008 Mar 10.
PMID: 18332042",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001682,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,bacterial one-hybrid ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra; Marcus Chibucos,,
http://purl.obolibrary.org/obo/OBI_0001592,purified MHC direct binding assay measuring half maximal effective concentration [EC50] of a MHC:ligand complex using fluorescence detection,half maximal effective concentration (EC50)|purified MHC/direct/fluorescence|nM,A purified MHC ligand binding half maximal effective concentration (EC50) determination assay that uses fluorescence detection to measure direct ligand binding.,false,,,http://purl.obolibrary.org/obo/OBI_0001991|http://purl.obolibrary.org/obo/OBI_0001499,,,,,,,,,,,,,,,,,,,A purified MHC ligand binding half maximal effective concentration (EC50) determination assay that uses fluorescence detection to measure direct ligand binding.,IEDB,,,,,,purified MHC direct binding assay measuring half maximal effective concentration [EC50] of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001592,,,,,,,,,,,,,,,,,,,,,,,,half maximal effective concentration (EC50)|purified MHC/direct/fluorescence|nM,,,,,,,,,,,,,,,,,,,,,,purified MHC direct binding assay measuring half maximal effective concentration [EC50] of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_1000024,cell pellet,,A material entity which results from the aggregation of cells produced by the application of centrifugal force to a liquid containing cells in suspension,false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,,,,,,,,,,,,,,,,A material entity which results from the aggregation of cells produced by the application of centrifugal force to a liquid containing cells in suspension,GROUP: CEBS|GROUP: OBI Biomaterial Branch,,,,,,cell pellet,,Detection of fetal DNA in a cell pellet after centrifugation of mountant. J Forensic Sci. 2003 Jan;48(1):135-6. PMID: 12570214,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1000024,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0302886,,,cell pellet,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Helen Parkinson|PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001184,epitope protection experiment,protection from challenge ,an epitope intervention experiment that tests the efficacy of inducing an immune epitope response to prevent disease in a host. ,false,,,http://purl.obolibrary.org/obo/OBI_0001178,,,,,,,,,,,,,,,,,,,an epitope intervention experiment that tests the efficacy of inducing an immune epitope response to prevent disease in a host. ,,,,,,,epitope protection experiment,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001184,,,,,,,,,,,,,,,,,,,,,,,,protection from challenge ,,,,,,,,,,,,,,,,,,,,,,epitope protection experiment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0600015,group assignment,study assignment|cohort assignment,group assignment is a process which has an organism as specified input and during which a role is assigned,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,study assignment|cohort assignment,,,,,,,,,,,,,,,group assignment is a process which has an organism as specified input and during which a role is assigned,OBI Plan,,,,,,group assignment,,Assigning' to be treated with active ingredient role' to an organism during group assignment. The group is those organisms that have the same role in the context of an investigation,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100026,,,,OBI:0600015,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,group assignment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000188,role of pathology review board,pathology review board,a worker role comprised of providing a confirmed and consensus diagnosis for histopathology results obtained during the investigation,false,,,http://purl.obolibrary.org/obo/OBI_0000116,,,,pathology review board,,,,,,,,,,,,,,,a worker role comprised of providing a confirmed and consensus diagnosis for histopathology results obtained during the investigation,,,,,,,role of pathology review board,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000188,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,role of pathology review board,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0001159,age since egg laying measurement datum,,"An age measurement datum that is the result of the measurement of the age of an organism since egg laying, the process of the production of egg(s) by an organism.",false,,,http://purl.obolibrary.org/obo/OBI_0001167,,,,,,,,,,,,,,,,,,,"An age measurement datum that is the result of the measurement of the age of an organism since egg laying, the process of the production of egg(s) by an organism.",MO_767 egg laying,,,,,,age since egg laying measurement datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001159,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,age since egg laying measurement datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001524,cell bound MHC direct binding assay measuring equilibrium association constant [KA] of a MHC:ligand complex using fluorescence detection,association constant KA|cellular MHC/direct/fluorescence|1/M,A cell bound MHC ligand binding equilibrium association constant (KA) determination assay that uses fluorescence detection to detect direct binding.,false,,,http://purl.obolibrary.org/obo/OBI_0001987|http://purl.obolibrary.org/obo/OBI_0001499,,,,,,,,,,,,,,,,,,,A cell bound MHC ligand binding equilibrium association constant (KA) determination assay that uses fluorescence detection to detect direct binding.,IEDB,,,,,,cell bound MHC direct binding assay measuring equilibrium association constant [KA] of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001524,,,,,,,,,,,,,,,,,,,,,,,,association constant KA|cellular MHC/direct/fluorescence|1/M,,,,,,,,,,,,,,,,,,,,,,cell bound MHC direct binding assay measuring equilibrium association constant [KA] of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001070,scintillation counter,,A device that is used to measure ionizing radiation.,false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,A device that is used to measure ionizing radiation.,http://en.wikipedia.org/wiki/Scintillation_counter,,,,,,scintillation counter,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001070,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,scintillation counter,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001252,array platform variation design,,"A study design in which the array platform is compared, e.g. Agilent versus Affymetrix.",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A study design in which the array platform is compared, e.g. Agilent versus Affymetrix.",MO_899 array_platform_variation_design,,,,,,array platform variation design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000208,,,,,,,,,,,,,,,,OBI:0001252,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,array platform variation design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/IAO_0000184,scatter plot,scattergraph,"A scatterplot is a graph which uses Cartesian coordinates to display values for two variables for a set of data. The data is displayed as a collection of points, each having the value of one variable determining the position on the horizontal axis and the value of the other variable determining the position on the vertical axis.",false,,,http://purl.obolibrary.org/obo/IAO_0000038,,,,scattergraph,,,,,,,,,,,,,,,"A scatterplot is a graph which uses Cartesian coordinates to display values for two variables for a set of data. The data is displayed as a collection of points, each having the value of one variable determining the position on the horizontal axis and the value of the other variable determining the position on the vertical axis.",WEB: http://en.wikipedia.org/wiki/Scatterplot,,,,,,scatter plot,,Comparison of gene expression values in two samples can be displayed in a scatter plot,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000184,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,scatter plot,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:James Malone|PERSON:Chris Stoeckert|PERSON:Melanie Courtot,,
http://purl.obolibrary.org/obo/CHEBI_33839,macromolecule,polymer,"A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.",false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,polymer,,,,,,,,,,,,,,,"A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.",,,,,,,macromolecule,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:33839,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,macromolecule,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000679,average value,arithmetic mean,A  data item that is produced as the output of an averaging data transformation and represents the average value of the input data.,false,,,http://purl.obolibrary.org/obo/IAO_0000027,,,,arithmetic mean,,,,,,,,,,,,,,,A  data item that is produced as the output of an averaging data transformation and represents the average value of the input data.,,,,,,,average value,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000679,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,average value,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: James Malone|PERSON: Monnie McGee,,
http://purl.obolibrary.org/obo/OBI_0400070,Luminex 200,,"A Luminex_200 is a flow_cytometer_analyser manufactured by Luminex. The optical specifications are: Reporter laser: 532 nm, nominal output 10 - 15 mW, maximum 500 mW, frequency-doubled diode; mode of operation, continuous wave (CW). Classification laser: 635 nm, 9.1 __ 6%, maximum output 25 mW, diode; mode of operation, continuous wave (CW) Reporter detector: Photomultiplier tube, detection bandwidth of 565 - 585 nm Classification detector and doublet discriminator: Avalanche photo diodes with temperature compensation",false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,,,,,,,,,,,,,,,,"A Luminex_200 is a flow_cytometer_analyser manufactured by Luminex. The optical specifications are: Reporter laser: 532 nm, nominal output 10 - 15 mW, maximum 500 mW, frequency-doubled diode; mode of operation, continuous wave (CW). Classification laser: 635 nm, 9.1 __ 6%, maximum output 25 mW, diode; mode of operation, continuous wave (CW) Reporter detector: Photomultiplier tube, detection bandwidth of 565 - 585 nm Classification detector and doublet discriminator: Avalanche photo diodes with temperature compensation",http://www.luminexcorp.com/support/faqs.html,,,,,,Luminex 200,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400070,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Luminex 200,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0001813,ELISPOT assay measuring epitope specific interleukin-27 production by T cells,IL-27 release|ELISPOT,An assay of epitope specific interleukin-27 production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001198,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-27 production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific interleukin-27 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001813,,,,,,,,,,,,,,,,,,,,,,,,IL-27 release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific interleukin-27 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000842,informing subject of study arm,,"A process in which the subject is made aware of which study arm they are participating in, for example whether they are receiving a placebo or a treatment with an investigational compound.",false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,,"A process in which the subject is made aware of which study arm they are participating in, for example whether they are receiving a placebo or a treatment with an investigational compound.",,,,,,09/28/2009 Alan Ruttenberg. This and the class informing-investigator-of-study-arm are defined in order to solve the question of how to represent single and double blind experiments. To represent the aspect of blinding pertaining to subjects (happens in single and double blinding) we say that that the study execution doesn't include any processes of this sort,informing subject of study arm,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000842,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,informing subject of study arm,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0000844,hospital,,A medical organization at which sick or injured people are given clinical care,false,,,http://purl.obolibrary.org/obo/OBI_0000245,,,,,,,,,,,,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,,A medical organization at which sick or injured people are given clinical care,http://www.golovchenko.org/cgi-bin/wnsearch?q=hospital#2n|modified from the wording of the wordnet definition,,,,,,hospital,,human ethics approval was obtained from the Southern Tasmania Health & Medical Human Research Ethics Committee and the Royal Hobart Hospital Research Ethics Committee [pmid:19696660],,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000844,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,hospital,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Helen Parkinson|Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0200184,descriptive statistical calculation data transformation,,"A descriptive statistical calculation data transformation is a data transformation that has objective descriptive statistical calculation and which concerns any calculation intended to describe a feature of a data set, for example, its center or its variability.",false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,"A descriptive statistical calculation data transformation is a data transformation that has objective descriptive statistical calculation and which concerns any calculation intended to describe a feature of a data set, for example, its center or its variability.",PERSON: James Malone,,,,,,descriptive statistical calculation data transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200184,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,descriptive statistical calculation data transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0000945,vibration isolation table,,A device  that supports another device such as a precision instrument by isolating it from vibration that is transmitted from the floor.,false,,,http://purl.obolibrary.org/obo/OBI_0001034,,,,,,,,,,,,,,,,,,,A device  that supports another device such as a precision instrument by isolating it from vibration that is transmitted from the floor.,United States Patent 6877711,,,,,,vibration isolation table,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000401,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000945,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,vibration isolation table,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000613,Bruker SPE-NMR platform,,A Solid Phase Extraction (SPE) system provides an interface between liquid chromatography (LC) and NMR. For the process of LC-SPE  NMR a chromatographic separation is done and the peaks of interest are trapped on an individual SPE cartridge after the column. The peak selection is done either by UV detection or by evaluation of the on-line registered MS or MSn spectra.,false,,,http://purl.obolibrary.org/obo/OBI_0000596,,,,,,,,,,,,,,,,,NMR instrument|hyphenated NMR instrument platform,,A Solid Phase Extraction (SPE) system provides an interface between liquid chromatography (LC) and NMR. For the process of LC-SPE  NMR a chromatographic separation is done and the peaks of interest are trapped on an individual SPE cartridge after the column. The peak selection is done either by UV detection or by evaluation of the on-line registered MS or MSn spectra.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400278,,,,,,Bruker SPE-NMR platform,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000613,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker SPE-NMR platform,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000145,pathologist role,Pathologist,a worker role of being responsible for making the histopathology diagnoses associated with data from a study; this activity occurs outside the study timeline,false,,,http://purl.obolibrary.org/obo/OBI_0000116,,,,Pathologist,,,,,,,,,,,,,,,a worker role of being responsible for making the histopathology diagnoses associated with data from a study; this activity occurs outside the study timeline,,,,,,,pathologist role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000145,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,pathologist role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0001547,material analysis service,,A service in which a service consumer provides some input material and a service provider performs some analysis of this material to generate data that is returned to the service consumer.,false,,,http://purl.obolibrary.org/obo/OBI_0001528,,,,,,,,,,,,,,,,,,,A service in which a service consumer provides some input material and a service provider performs some analysis of this material to generate data that is returned to the service consumer.,PERSON: Matthew Brush,,,,,,material analysis service,,Services performing DNA sequencing or Cell Analysis,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001547,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,material analysis service,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Carlo Torniai|PERSON: Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_0001960,taxonomic diversity assessment by targeted gene survey,targeted gene survey DNA barcoding|environmental gene survey|targeted gene survey,is an assay which aims to provide information about taxonomic information and community diversity by mean of sequencing specific genomic regions used as marker of identity or diversity.,false,,,http://purl.obolibrary.org/obo/OBI_0600047,,http://purl.obolibrary.org/obo/OBI_0001969,,targeted gene survey DNA barcoding,,,,,,,,,,,,,,,is an assay which aims to provide information about taxonomic information and community diversity by mean of sequencing specific genomic regions used as marker of identity or diversity.,OBI,,,,,,taxonomic diversity assessment by targeted gene survey,,"http://www.ncbi.nlm.nih.gov/pubmed/20679230

http://www.ncbi.nlm.nih.gov/pubmed/25367129",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001960,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,environmental gene survey|targeted gene survey,taxonomic diversity assessment by targeted gene survey,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001295,biological activity assay measuring epitope specific interleukin-17 production by T cells,IL-17 release|biological activity,A T cell epitope specific cytokine production assay that detects interleukin-17 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects interleukin-17 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific interleukin-17 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001295,,,,,,,,,,,,,,,,,,,,,,,,IL-17 release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific interleukin-17 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000871,viral hemagglutination assay,HI|viral hemeagglutination assay|HA,The viral hemagglutination assay (HA) is a quantification of viruses by hemagglutination.,false,,,http://purl.obolibrary.org/obo/OBI_0000443,,http://purl.obolibrary.org/obo/OBI_0000437,,HI|viral hemeagglutination assay|HA,,,,,,,,,,,,,,,The viral hemagglutination assay (HA) is a quantification of viruses by hemagglutination.,WEB: http://en.wikipedia.org/wiki/Hemagglutination_assay,,,,,,viral hemagglutination assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000906,,,,,,,,,,,,,,,,OBI:0000871,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,viral hemagglutination assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person: Bjoern Peters|person: Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_1110120,assay antigen role,,"Any molecule recognized by the adaptive immune receptors? Recognized means bound with a certain affinity? From GO ag binding:Interacting selectively with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen. see OBI_1110120 below",false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,,,"Any molecule recognized by the adaptive immune receptors? Recognized means bound with a certain affinity? From GO ag binding:Interacting selectively with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen. see OBI_1110120 below",IEDB,,,,,,assay antigen role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,assay antigen role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0200005,feature extraction objective,,A feature extraction objective is a data transformation objective where the aim of the data transformation is to generate quantified values from a scanned image.,false,,,http://purl.obolibrary.org/obo/OBI_0200166,,,,,,,,,,,,,,,,,,,A feature extraction objective is a data transformation objective where the aim of the data transformation is to generate quantified values from a scanned image.,TERM: http://mged.sourceforge.net/ontologies/MGEDOntology.owl#feature_extraction,,,,,,feature extraction objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200005,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,feature extraction objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0001910,primary cell culture,,A cell culture comprised of primary cultured cells and the media in which they are being actively propaged or quiescently stored.,false,,,http://purl.obolibrary.org/obo/OBI_0001876,,,,,,,,,,,,,,,,,,,A cell culture comprised of primary cultured cells and the media in which they are being actively propaged or quiescently stored.,OBI-CLO Alignment Working Group (Spring 2013),,,,,,primary cell culture,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CL_0000001,,,,,,,,,,,,,,,,OBI:0001910,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,primary cell culture,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_0001013,kethoxal structure mapping assay,,is a single-nucleotide-resolution nucleic acid structure mapping assay which uses kethoxal as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,false,,,http://purl.obolibrary.org/obo/OBI_0001017,,http://purl.obolibrary.org/obo/OBI_0000441,,,,,,,,,,,,,,,,,is a single-nucleotide-resolution nucleic acid structure mapping assay which uses kethoxal as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,RNA ontology,,,,,,kethoxal structure mapping assay,,single nucleotide resolution mapping assay using Kethoxal probe,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001013,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,kethoxal structure mapping assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001354,ELISPOT assay measuring epitope specific interleukin-17 production by T cells,IL-17 release|ELISPOT,An assay of epitope specific interleukin-17 production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001295,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-17 production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific interleukin-17 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001354,,,,,,,,,,,,,,,,,,,,,,,,IL-17 release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific interleukin-17 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/IAO_0000140,setting datum,,A settings datum is a datum that denotes some configuration of an instrument.,false,,,http://purl.obolibrary.org/obo/IAO_0000027,,,,,,,,,,,,,,,,,,,A settings datum is a datum that denotes some configuration of an instrument.,,,,,,"Alan grouped these in placeholder for the moment. Name by analogy to measurement datum.|2/3/2009 Feedback from OBI

This should be a ""setting specification"". There is a question of whether it is information about a realizable or not.

Pro other specification are about realizables.
Cons sometimes specifies a quality which is not a realizable.",setting datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,setting datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/NCBITaxon_6668,Daphnia,common water fleas,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_197562,,,,common water fleas,,,,,,,,,,,,,,,,,,,,,,Daphnia,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:6668,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Daphnia,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001445,biological activity assay measuring epitope specific interleukin-2 production by T cells,IL-2 release|biological activity,A T cell epitope specific cytokine production assay that detects interleukin-2 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects interleukin-2 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific interleukin-2 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001445,,,,,,,,,,,,,,,,,,,,,,,,IL-2 release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific interleukin-2 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001618,average depth of sequence coverage,Depth of Coverage - Average,An average value of the depth of sequence coverage based both on external (e.g. Cot-based size estimates) and internal (average coverage in the assembly) measures of genome size.,false,,,http://purl.obolibrary.org/obo/OBI_0000679,,,,,,,,,,,,,,,,,,,An average value of the depth of sequence coverage based both on external (e.g. Cot-based size estimates) and internal (average coverage in the assembly) measures of genome size.,NIAID GSCID-BRC metadata working group,,,,,,average depth of sequence coverage,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001618,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,average depth of sequence coverage,,,,,,Depth of Coverage - Average,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000182,nuclear magnetic resonance 3D structure determination assay,,A 3D structure determination assay that uses magnetic properties of atomic nuclei to determine the 3D structure and dynamics of molecules in the input sample.,false,,,http://purl.obolibrary.org/obo/OBI_0600045,,,,,,,,,,,,,,,,,,,A 3D structure determination assay that uses magnetic properties of atomic nuclei to determine the 3D structure and dynamics of molecules in the input sample.,IEDB,,,,,,nuclear magnetic resonance 3D structure determination assay,,"Determining the binding of epitope-specific nanobody cAb-HuL5 to wild type human lysozyme by chemical shift perturbations in NMR spectra (Erwin De Genst, J Phys Chem B 2013).",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000182,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,nuclear magnetic resonance 3D structure determination assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PlanAndPlannedProcess Branch, IEDB",,
http://purl.obolibrary.org/obo/GO_0007049,cell cycle,,"The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.",false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,"The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.",,,,,,,cell cycle,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0007049,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,cell cycle,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001125,laser scanning confocal microscope,,"A confocal microscope that obtains high-resolution optical images with depth selectivity, in which a laser beam passes through a light source aperture and then is focused by an objective lens into a small (ideally diffraction limited) focal volume within or on the surface of a specimen.",false,,,http://purl.obolibrary.org/obo/OBI_0001079,,,,,,,,,,,,,,,,,,,"A confocal microscope that obtains high-resolution optical images with depth selectivity, in which a laser beam passes through a light source aperture and then is focused by an objective lens into a small (ideally diffraction limited) focal volume within or on the surface of a specimen.",http://en.wikipedia.org/wiki/Confocal_laser_scanning_microscopy,,,,,,laser scanning confocal microscope,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,laser scanning confocal microscope,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/PATO_0002243,fluid flow rate,,A physical quality inhering in a fluid (liquid or gas) by virtue of the amount of fluid which passes through a given surface per unit time.,false,,,http://purl.obolibrary.org/obo/PATO_0001237,,,,,,,,,,,,,,,,,,,A physical quality inhering in a fluid (liquid or gas) by virtue of the amount of fluid which passes through a given surface per unit time.,,,,,,,fluid flow rate,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0002243,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,fluid flow rate,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000208,methodology testing objective,,Methodology_testing_objective is an objective role carried out by a proposition defining the aim of the study is to examine the effect of using different methodologies.,false,,,http://purl.obolibrary.org/obo/IAO_0000005,,,,,,,,,,,,,,,,,,,Methodology_testing_objective is an objective role carried out by a proposition defining the aim of the study is to examine the effect of using different methodologies.,,,,,,,methodology testing objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000208,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,methodology testing objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0000981,agar stab specimen,,a specimen that is output of a process that cell culture inoculated into agar for long term storage.,false,,,http://purl.obolibrary.org/obo/OBI_0001472,,,,,,,,,,,,,,,,,,,a specimen that is output of a process that cell culture inoculated into agar for long term storage.,MO_971 agar_stab,,,,,,agar stab specimen,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000981,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,agar stab specimen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Chris Stoeckert|PERSON: Jie Zheng,,
http://purl.obolibrary.org/obo/OBI_0001533,data storage service,,A storage service in which a service consumer provides data as input which a service provider stores and returns as output in its original form.,false,,,http://purl.obolibrary.org/obo/OBI_0001530,,,,,,,,,,,,,,,,,,,A storage service in which a service consumer provides data as input which a service provider stores and returns as output in its original form.,PERSON: Matthew Brush,,,,,,data storage service,,A service offering data backup,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001533,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,data storage service,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Carlo Torniai|PERSON: Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_0000663,class prediction data transformation,supervised classification data transformation,A class prediction data transformation (sometimes called supervised classification) is a data transformation that has objective class prediction.,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,supervised classification data transformation,,,,,,,,,,,,,,,A class prediction data transformation (sometimes called supervised classification) is a data transformation that has objective class prediction.,PERSON: James Malone,,,,,,class prediction data transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000663,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,class prediction data transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0001952,flash freezing,,"A freezing process by which material entities are quickly frozen by subjecting them to cryogenic temperatures, or in direct contact with Liquid nitrogen at -320.8F or -196°C. ",false,,,http://purl.obolibrary.org/obo/OBI_0001953,,,,,,,,,,,,,,,,,,,"A freezing process by which material entities are quickly frozen by subjecting them to cryogenic temperatures, or in direct contact with Liquid nitrogen at -320.8F or -196°C. ",WEB: http://en.wikipedia.org/wiki/Flash_freezing,,,,,,flash freezing,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001952,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,flash freezing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Mathias Brochhausen, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000637,gas chromatography detector,FID,"A gas chromatography detector is a chromatography detector that locates in the dimensions of space and time, the positions of the components of a mixture that has been subjected to a gas chromatographic process and thus permits the senses to appreciate the nature of the separation. There is no LC detector that has an equivalent performance to the flame ionization detector (FID) used in GC. In general, LC detectors have sensitivities of two to three orders of magnitude less than their GC counterparts and linear dynamic ranges one to two orders of magnitude lower. Only highly specific LC detectors have sensitivities that can approach those of GC detectors.",false,,,http://purl.obolibrary.org/obo/OBI_0000481,,,,FID,,,,,,,,,,,,,"chromatography detector, defined class/xps",,"A gas chromatography detector is a chromatography detector that locates in the dimensions of space and time, the positions of the components of a mixture that has been subjected to a gas chromatographic process and thus permits the senses to appreciate the nature of the separation. There is no LC detector that has an equivalent performance to the flame ionization detector (FID) used in GC. In general, LC detectors have sensitivities of two to three orders of magnitude less than their GC counterparts and linear dynamic ranges one to two orders of magnitude lower. Only highly specific LC detectors have sensitivities that can approach those of GC detectors.",WEB:<http://www.chromatography-online.org/GC-Detectors/Classification/rs1.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01083,,,,,,gas chromatography detector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000637,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,gas chromatography detector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001477,lowess transformation,,"A data transformation of normalizing ratio data by using a locally weighted polynomial regression (typically after a log transformation). The regression can be performed on log ratios resulting from the relation of two data sets versus the average log intensity data from the same two data sets or it can be performed on raw or log transformed values from one data set versus values from another. The goal could be to remove intensity-dependent dye-specific effects from the set of pair wise ratios. This method can be applied globally, or limited by one or more specified criteria. ",false,,,http://purl.obolibrary.org/obo/OBI_0200169,,http://purl.obolibrary.org/obo/OBI_0200167,,,,,,,,,,,,,,,,,"A data transformation of normalizing ratio data by using a locally weighted polynomial regression (typically after a log transformation). The regression can be performed on log ratios resulting from the relation of two data sets versus the average log intensity data from the same two data sets or it can be performed on raw or log transformed values from one data set versus values from another. The goal could be to remove intensity-dependent dye-specific effects from the set of pair wise ratios. This method can be applied globally, or limited by one or more specified criteria. ",MO_720 lowess_normalization,,,,,,lowess transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001477,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,lowess transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0302885,filtration,,filtration is a process which separates components suspended in a fluid based on granularity properties relying on a filter device,false,,,http://purl.obolibrary.org/obo/OBI_0600014,,http://purl.obolibrary.org/obo/OBI_0000681,,,,,,,,,,,,,,,,,filtration is a process which separates components suspended in a fluid based on granularity properties relying on a filter device,OBI-Branch: adapted from wikipedia and wordnet,,,,,,filtration,,PMID: 18524968.Filtration of CSF improves isolation of Mycobacteria.J Clin Microbiol. 2008 Jun 4.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000151,,,,,,,,,,,,,,,OBI:0302885,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,filtration,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0302867,predicted data item,,A data item that was generated on the basis of a calculation or logical reasoning,false,,,http://purl.obolibrary.org/obo/IAO_0000027,,,,,,,,,,,,,,,,,,,A data item that was generated on the basis of a calculation or logical reasoning,,,,,,"BP 12/21: Edited the incomplete definition from Philippe. It is still unclear to me if this should be a data item at all, or an information content entity. This will be important, because if we exclude predictions from data items, we will run into issues that we willl have to duplicate things like 'weight datum' etc. all of which can be predicted. ",predicted data item,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302867,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,predicted data item,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra; Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000415,polymerase chain reaction,PCR,"PCR is the process in which a DNA polymerase is used to amplify a piece of DNA by in vitro enzymatic replication. As PCR progresses, the DNA thus generated is itself used as a template for replication. This sets in motion a chain reaction in which the DNA template is exponentially amplified.",false,,,http://purl.obolibrary.org/obo/OBI_0600058,,http://purl.obolibrary.org/obo/OBI_0000456,,PCR,,,,,,,,,,,,,,,"PCR is the process in which a DNA polymerase is used to amplify a piece of DNA by in vitro enzymatic replication. As PCR progresses, the DNA thus generated is itself used as a template for replication. This sets in motion a chain reaction in which the DNA template is exponentially amplified.",adapted from wikipedai,,,,,,polymerase chain reaction,,Opisthorchis viverrini: Detection by polymerase chain reaction (PCR) in human stool samples. Exp Parasitol. 2008 Sep 9.  PMID: 18805413,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_16991,http://purl.obolibrary.org/obo/OBI_0000406,,,OBI:0000415,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,polymerase chain reaction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI Plan,,
http://purl.obolibrary.org/obo/OBI_0000817,fucoidan,,"Fucoidan is a sulfated polysaccharide (MW: average 20,000) found mainly in various species of brown seaweed such as kombu, limu moui,bladderwrack, wakame, mozuku, and hijiki (variant forms of fucoidan have also been found in animal species, including the sea cucumber).",false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,"Fucoidan is a sulfated polysaccharide (MW: average 20,000) found mainly in various species of brown seaweed such as kombu, limu moui,bladderwrack, wakame, mozuku, and hijiki (variant forms of fucoidan have also been found in animal species, including the sea cucumber).",http://en.wikipedia.org/wiki/Fucoidan,,,,,,fucoidan,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000817,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,fucoidan,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0001962,target gene specification,target gene,"is a directive information specifying a coding genomic region which is the focus of a planned process such as an assay, for instance in a environmental gene survey",false,,,http://purl.obolibrary.org/obo/IAO_0000033,,,,,,,,,,,,,,,,,,,"is a directive information specifying a coding genomic region which is the focus of a planned process such as an assay, for instance in a environmental gene survey",PRS for OBI,,,,,,target gene specification,,"http://www.ncbi.nlm.nih.gov/pubmed/25367129

""performing a profiling of microbial phylogenetic composition using sequencing of 16S rRNA gene (used as target gene)",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001962,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,target gene,target gene specification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000838,material maintenance,,a process with that achieves the objective to maintain some or all of the characteristics of an input material over time,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,,,a process with that achieves the objective to maintain some or all of the characteristics of an input material over time,,,,,,,material maintenance,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000838,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,material maintenance,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/UBERON_0000165,mouth,,"The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes gums, lips, tongue and parts of the palate. Typically also includes the teeth, except where these occur elsewhere (e.g. pharyngeal jaws) or protrude from the mouth (tusks).",false,,,http://purl.obolibrary.org/obo/CARO_0000055,,,,,,,,,,,,,,,,,,,"The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes gums, lips, tongue and parts of the palate. Typically also includes the teeth, except where these occur elsewhere (e.g. pharyngeal jaws) or protrude from the mouth (tusks).",,,,,,,mouth,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UBERON:0000165,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uberon.owl,,,,,,,,,,,,,,,,,,,mouth,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000441,assay objective,,an objective specification to determine a specified type of information about an evaluated entity (the material entity bearing evaluant role),false,,,http://purl.obolibrary.org/obo/IAO_0000005,,,,,,,,,,,,,,,,,,,an objective specification to determine a specified type of information about an evaluated entity (the material entity bearing evaluant role),PPPB branch,,,,,,assay objective,,the objective to determine the weight of a mouse.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000441,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,assay objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PPPB branch,,
http://purl.obolibrary.org/obo/OBI_0600042,recombinant plasmid cloning,,the insertion of a particular DNA fragment into a plasmid in order to make copies of a biomaterial,false,,,http://purl.obolibrary.org/obo/OBI_0600064,,,,,,,,,,,,,,,,,,,the insertion of a particular DNA fragment into a plasmid in order to make copies of a biomaterial,OBI branch derived,,,,,,recombinant plasmid cloning,,The DNA fragment encoding the p35 gene from Mycobacterium avium complex was inserted into pcDNAII and expressed in E coli in order to study p35.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600042,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,recombinant plasmid cloning,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Kevin Clancy,,
http://purl.obolibrary.org/obo/OBI_0000345,mass analyzer,,A Mass analyzer is a device that separates ions according to their mass-to-charge ratio. All mass spectrometers are based on dynamics of charged particles in electric and magnetic fields in vacuum where the two laws of Lorentz force law and Newton's second law of motion apply.,false,,,http://purl.obolibrary.org/obo/OBI_0000832|http://purl.obolibrary.org/obo/OBI_0000932,,,,,,,,,,,,,,,,,,,A Mass analyzer is a device that separates ions according to their mass-to-charge ratio. All mass spectrometers are based on dynamics of charged particles in electric and magnetic fields in vacuum where the two laws of Lorentz force law and Newton's second law of motion apply.,http://en.wikipedia.org/wiki/Mass_spectrometry#Mass_analyzer,,,,,,mass analyzer,,The mass analyzer of the Voyager-DE(tm) STR Biospectrometry Workstation,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453|http://purl.obolibrary.org/obo/OBI_0000372,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000345,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,mass analyzer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Daniel Schober|Frank Gibson,,
http://purl.obolibrary.org/obo/OBI_0000968,device,instrument,"A material entity that is designed to perform a function in a scientific investigation, but is not a reagent.",false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,instrument,,,,,,,,,,,,,,,"A material entity that is designed to perform a function in a scientific investigation, but is not a reagent.",OBI development call 2012-12-17.,,,,,"2012-12-17 JAO: In common lab usage, there is a distinction made between devices and reagents that is difficult to model. Therefore we have chosen to specifically exclude reagents from the definition of ""device"", and are enumerating the types of roles that a reagent can perform.

2013-6-5 MHB: The following clarifications are outcomes of the May 2013 Philly Workshop. Reagents are distinguished from devices that also participate in scientific techniques by the fact that reagents are chemical or biological in nature and necessarily participate in some chemical interaction or reaction during the realization of their experimental role. By contrast, devices do not participate in such chemical reactions/interactions.  Note that there are cases where devices use reagent components during their operation, where the reagent-device distinction is less clear.  For example:

(1) An HPLC machine is considered a device, but has a column that holds a stationary phase resin as an operational component.  This resin qualifies as a device if it participates purely in size exclusion, but bears a reagent role that is realized in the running of a column if it interacts electrostatically or chemically with the evaluant. The container the resin is in (“the column”) considered alone is a device. So the entire column as well as the entire HPLC machine are devices that have a reagent as an operating part.

(2) A pH meter is a device, but its electrode component bears a reagent role in virtue of its interacting directly with the evaluant in execution of an assay.

(3) A gel running  box  is a device that has a metallic lead as a component that participates in a chemical reaction with the running buffer when a charge is passed through it.  This metallic lead is considered to have a reagent role as a component of this device realized in the running of a gel.

In the examples above, a reagent is an operational component of a device, but the device itself does not realize a reagent role (as bearing a reagent role is not transitive across the part_of relation).  In this way, the asserted disjointness between a reagent and device holds, as both roles are never realized in the same bearer during execution of an assay.  ",device,,A voltmeter is a measurement device which is intended to perform some measure function.|An autoclave is a device that sterlizes instruments or contaminated waste by applying high temperature and pressure.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000968,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000094,,,device,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0001580,material transport service,,A service in which a service provider facilitates the transport of some material entity to a specified destination for the service consumer.,false,,,http://purl.obolibrary.org/obo/OBI_0001528,,,,,,,,,,,,,,,,,,,A service in which a service provider facilitates the transport of some material entity to a specified destination for the service consumer.,PERSON: Carlo Torniai,,,,,,material transport service,,A service for chemical disposal,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001580,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,material transport service,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Carlo Torniai|PERSON: Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_0200164,proportion of expected false positives correction method,PEFP correction method,A proportion of expected false positives correction method is a multiple testing procedure that controls the ratio of the expected value of the numbers of false positives to the expected value of the numbers of rejected hypotheses.,false,,,http://purl.obolibrary.org/obo/OBI_0200089,,,,PEFP correction method,,,,,,,,,,,,,,,A proportion of expected false positives correction method is a multiple testing procedure that controls the ratio of the expected value of the numbers of false positives to the expected value of the numbers of rejected hypotheses.,"Dudoit, Sandrine and van der Laan, Mark J. (2008) Multiple Testing Procedures with Applications to Genomics.  New York: Springer , p. 21",,,,,,proportion of expected false positives correction method,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200164,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,proportion of expected false positives correction method,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Monnie McGee,,
http://purl.obolibrary.org/obo/OBI_0400016,BioSorter250,,"A BioSorter250 is a flow_cytometer_sorter manufactured by Union Biometrica. It includes analog electronics, 488/514 nm multi-line Argon-ion laser for fluorescence and a light stabilized 670 nm forward scatter laser for extinction and time-of-flight. It has filters and PMTs for 3 fluorescent parameters and photodiodes for scatter, time of flight, and extinction. The flow cell is quartz cuvette. The BioSorterTM 250 is an instrument for analyzing and sorting objects from 40-200 microns in diameter.",false,,,http://purl.obolibrary.org/obo/OBI_0400099,,,,,,,,,,,,,,,,,,,"A BioSorter250 is a flow_cytometer_sorter manufactured by Union Biometrica. It includes analog electronics, 488/514 nm multi-line Argon-ion laser for fluorescence and a light stabilized 670 nm forward scatter laser for extinction and time-of-flight. It has filters and PMTs for 3 fluorescent parameters and photodiodes for scatter, time of flight, and extinction. The flow cell is quartz cuvette. The BioSorterTM 250 is an instrument for analyzing and sorting objects from 40-200 microns in diameter.",http://www.unionbio.com/products/BioSorter.html,,,,,,BioSorter250,,BioSorter 250 at TSRI Flow Cytometry Core Facility,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400016,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BioSorter250,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0000162,complete nutrient role,complete nutrient,A nutrient role that inheres in a material entity and is realized in the use of that material entity by an organism to provide all needed nourishment.,false,,,http://purl.obolibrary.org/obo/OBI_0000204,,,,complete nutrient,,,,,,,,,,,,,,,A nutrient role that inheres in a material entity and is realized in the use of that material entity by an organism to provide all needed nourishment.,,,,,,,complete nutrient role,,"Rat chow; RPMI medium + serum; use example:  CNS17 (Complete Nutrient System) Grow 3-2-4, http://www.kalyx.com/store/proddetail.cfm/ItemID/552307/CategoryID/12000/SubCatID/2755/file.htm",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000162,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,complete nutrient role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0000697,Helicos sequencing,true single molecule sequencing,is a DNA sequencing which allows sequence identification of billions of DNA molecules immobilized to a surface by using DNA polymerase and fluorescently labeled nucleotides added one at a time. The sequencing process does not requires amplification step and is typically able to produce reads of 25 base pair length.,false,,,http://purl.obolibrary.org/obo/OBI_0000734,,,,true single molecule sequencing,,,,,,,,,,,,,,,is a DNA sequencing which allows sequence identification of billions of DNA molecules immobilized to a surface by using DNA polymerase and fluorescently labeled nucleotides added one at a time. The sequencing process does not requires amplification step and is typically able to produce reads of 25 base pair length.,adapted from wikipedia,,,,,,Helicos sequencing,,"PMID: 18388294. Single-molecule DNA sequencing of a viral genome.
Harris TD, Buzby PR, Babcock H, Beer E, Bowers J, Braslavsky I, Causey M, Colonell J, Dimeo J, Efcavitch JW, Giladi E, Gill J, Healy J, Jarosz M, Lapen D, Moulton K, Quake SR, Steinmann K, Thayer E, Tyurina A, Ward R, Weiss H, Xie Z. Science. 2008 Apr 4;320(5872):106-9.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000717,,,,,,,,,,,,,,,OBI:0000697,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0302902,,,,,,,,,,,,,,,,,,,,,Helicos sequencing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/CLO_0009251,CLO_0009251,,,false,,,http://purl.obolibrary.org/obo/CLO_0000578,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CLO:0009251,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0400158,digital-to-analog converter,,A digital-to-analog_converter is an instrument that converts a finite resolution digital signal into an infinite resolution analog signal.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A digital-to-analog_converter is an instrument that converts a finite resolution digital signal into an infinite resolution analog signal.,PERSON: Daniel Schober,,,,,,digital-to-analog converter,,"A digital-to-analog_converter is used to convert a computergenerated discrete signal into a continuous analog one, e.g. a sound.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000393,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400158,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,digital-to-analog converter,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001657,ELISA measuring binding of a B cell epitope:antibody complex,qualitative binding|ELISA,A B cell epitope qualitative binding to antibody assay that uses an enzyme-linked immunosorbent assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001703,,,,,,,,,,,,,,,,,,,A B cell epitope qualitative binding to antibody assay that uses an enzyme-linked immunosorbent assay.,IEDB,,,,,,ELISA measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001657,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000101,measured expression level,,"A measurement datum that is the outcome of the quantification of an assay for the activity of a gene, or the number of RNA transcripts.",false,,,http://purl.obolibrary.org/obo/IAO_0000109,,,,,,,,,,,,,,,,,,,"A measurement datum that is the outcome of the quantification of an assay for the activity of a gene, or the number of RNA transcripts.",OBI Data Transformation branch,,,,,,measured expression level,,"Examples are quantified data from an expression microarray experiment, PCR measurements, etc.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000101,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,measured expression level,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0000218,investigation results report,,An investigation report is a report on the results of an investigation.,false,,,http://purl.obolibrary.org/obo/IAO_0000088,,,,,,,,,,,,,,,,,,,An investigation report is a report on the results of an investigation.,group:OBI,,,,,,investigation results report,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000218,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,investigation results report,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0001723,assay measuring the off rate [koff] of a B cell epitope:antibody complex,off rate|binding assay|1/s,A B cell epitope binding constant determination assay that measures the off rate.,false,,,http://purl.obolibrary.org/obo/OBI_0001709,,,,,,,,,,,,,,,,,,,A B cell epitope binding constant determination assay that measures the off rate.,IEDB,,,,,,assay measuring the off rate [koff] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001723,,,,,,,,,,,,,,,,,,,,,,,,off rate|binding assay|1/s,,,,,,,,,,,,,,,,,,,,,,assay measuring the off rate [koff] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000213,fluorescence compensation matrix,,"A fluorescence compensation matrix is a square matrix which is used as the left multiplier of the vector of fluorescence values while performing digital fluorescence compensation. Also, fluorescence compensation matrix is the inverse of the fluorescence spillover matrix.",false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,,,,,,,,,,,,,,,,"A fluorescence compensation matrix is a square matrix which is used as the left multiplier of the vector of fluorescence values while performing digital fluorescence compensation. Also, fluorescence compensation matrix is the inverse of the fluorescence spillover matrix.",group:Flow Cytometry community,,,,,,fluorescence compensation matrix,,"((1.053096, -0.22476), (-0.24877, 1.053096))",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000213,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,fluorescence compensation matrix,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0001868,genetic material,genomic material|hereditary genetic material,"A nucleic acid macromolecule that is part of a cell or virion and is inherited from an immediate ancestor, or incorporated in a manner that it has the disposition to be replicated and inherited by descendants.|Naturally occurring or experimentally incorporated nucleic acids that meet these criteria can qualify as genetic/genomic material.

Qualifying examples include: (1) inherited chromosomal DNA in germ cells, stem cells, fully differentiated cells, or cell line cells, or the DNA/RNA content of a virion; (2) natural replicons exchanged through horizontal gene transfer mechanisms such as bacterial conjugation, which are capable of replication and inheritance by progeny; (3) a chromosomally integrated  gene targeting DNA construct transfected into a cell; or (4) a stable extra-chromosomal replicon delivered into cells, such as a plasmid in bacterial host with ori allowing indefinite propagation.  

Non-qualifying examples include a transiently transfected plasmid or siRNA oligo (as these are not able to be replicated and inherited by progeny cells).
",false,,,http://purl.obolibrary.org/obo/CHEBI_33696,,,,genomic material|hereditary genetic material,,,,,,,,,,,,,,,"A nucleic acid macromolecule that is part of a cell or virion and is inherited from an immediate ancestor, or incorporated in a manner that it has the disposition to be replicated and inherited by descendants.","OBI developer calls, March 4 2013 and March 11 2013",,,,,"MHB 3-22-13: Discussions are ongoing about the label of this class, given consideration of a second class that covers nucleic acid parts of cells or virions that participate in gene expression processes as a template for expression or a direct effector of expression of some other genetic element (e.g. an siRNA), but are not necessarily heritable by progeny or inherited from ancestors.  So things like transiently transfected plasmids and siRNAs would qualify as instances of this second class, but not of 'genetic material' as defined here.

Also, OBI needs to import a class representing virions for an axiom on genetic material (part_of some (cell or virion).",genetic material,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000428,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001868,,,,,,,,,,,,,,,,,,"Naturally occurring or experimentally incorporated nucleic acids that meet these criteria can qualify as genetic/genomic material.

Qualifying examples include: (1) inherited chromosomal DNA in germ cells, stem cells, fully differentiated cells, or cell line cells, or the DNA/RNA content of a virion; (2) natural replicons exchanged through horizontal gene transfer mechanisms such as bacterial conjugation, which are capable of replication and inheritance by progeny; (3) a chromosomally integrated  gene targeting DNA construct transfected into a cell; or (4) a stable extra-chromosomal replicon delivered into cells, such as a plasmid in bacterial host with ori allowing indefinite propagation.  

Non-qualifying examples include a transiently transfected plasmid or siRNA oligo (as these are not able to be replicated and inherited by progeny cells).
",,,,,,,,,,,,,,,,,,,,,,,,,,,,genetic material,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/IAO_0000037,dot plot,,A dot plot is a report graph which is a graphical representation of data where each data point is represented by a single dot placed on coordinates corresponding to data point values in particular dimensions.,false,,,http://purl.obolibrary.org/obo/IAO_0000038,,,,,,,,,,,,,,,,,,,A dot plot is a report graph which is a graphical representation of data where each data point is represented by a single dot placed on coordinates corresponding to data point values in particular dimensions.,OBI_0000123|group:OBI,,,,,,dot plot,,Dot plot of SSC-H and FSC-H.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000002,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000037,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,dot plot,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Allyson Lister|person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0001679,yeast 2-hybrid ,Y2H,"yeast 2 hybrid screen is an assay meant  to discover protein–protein interactions and protein–DNA interactions by testing for physical interactions (such as binding) between two proteins or a single protein and a DNA molecule, respectively. The premise behind the test is the activation of downstream reporter gene(s) by the binding of a transcription factor onto an upstream activating sequence (UAS). For two-hybrid screening, the transcription factor is split into two separate fragments, called the binding domain (BD) and activating domain (AD). The BD is the domain responsible for binding to the UAS and the AD is the domain responsible for the activation of transcription.[1][2] The Y2H is thus a protein-fragment complementation assay.",false,,,http://purl.obolibrary.org/obo/OBI_0000070|http://purl.obolibrary.org/obo/OBI_0001146,,,,Y2H,,,,,,,,,,,,,add regulatory region DNA binding;GO:0043565;,,"yeast 2 hybrid screen is an assay meant  to discover protein–protein interactions and protein–DNA interactions by testing for physical interactions (such as binding) between two proteins or a single protein and a DNA molecule, respectively. The premise behind the test is the activation of downstream reporter gene(s) by the binding of a transcription factor onto an upstream activating sequence (UAS). For two-hybrid screening, the transcription factor is split into two separate fragments, called the binding domain (BD) and activating domain (AD). The BD is the domain responsible for binding to the UAS and the AD is the domain responsible for the activation of transcription.[1][2] The Y2H is thus a protein-fragment complementation assay.",adapted from wikipedia,,,,,,yeast 2-hybrid ,,"Strong FANCA/FANCG but weak FANCA/FANCC interaction in the yeast 2-hybrid system.
Reuter T, Herterich S, Bernhard O, Hoehn H, Gross HJ.
Blood. 2000 Jan 15;95(2):719-20.
PMID: 10627486",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001679,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,yeast 2-hybrid ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra; Marcus Chibucos,,
http://purl.obolibrary.org/obo/IAO_0000101,image,,"An image is an affine projection to a two dimensional surface, of measurements of some quality of an entity or entities repeated at regular intervals across a spatial range, where the measurements are represented as color and luminosity on the projected on surface.",false,,,http://purl.obolibrary.org/obo/IAO_0000308,,,,,,,,,,,,,,,,,,,"An image is an affine projection to a two dimensional surface, of measurements of some quality of an entity or entities repeated at regular intervals across a spatial range, where the measurements are represented as color and luminosity on the projected on surface.",OBI_0000030|group:OBI,,,,,,image,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000101,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,image,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Alan Ruttenberg|person:Allyson|person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0400155,water bath,,A water bath is a temperature control bath in which a water acts as contact medium enabling temperature transfer from the heating element or cooling element to the sample. The temperature can be controlled in the 0 to 100 degree centigrade range (under normal pressure).,false,,,http://purl.obolibrary.org/obo/OBI_0400120,,,,,,,,,,,,,,,,,,,A water bath is a temperature control bath in which a water acts as contact medium enabling temperature transfer from the heating element or cooling element to the sample. The temperature can be controlled in the 0 to 100 degree centigrade range (under normal pressure).,PERSON: Daniel Schober,,,,,,water bath,,A water bath was used to allow for cell incubation at 38 degree centigrade for 8 hours.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400155,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,water bath,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001305,genotype information,,"a genetic characteristics information that is about the genetic material of an organism and minimally includes information about the genetic background and can in addition contain information about specific alleles, genetic modifications, etc.",false,,,http://purl.obolibrary.org/obo/OBI_0001404,,,,,,,,,,,,,,,,,,,"a genetic characteristics information that is about the genetic material of an organism and minimally includes information about the genetic background and can in addition contain information about specific alleles, genetic modifications, etc.",Group: OBI group,,,,,"discussed on San Diego OBI workshop, March 2011",genotype information,,"Genotype information can be: Mus musculus wild type (in this case the genetic population background information is Mus musculus), C57BL/6J  Hnf1a+/- (in this case, C57BL/6J is the genetic population background information and Hnf1a+/- is the allele information",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001305,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,genotype information,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Group: OBI group,,
http://purl.obolibrary.org/obo/OBI_0001662,NMR assay measuring binding of a B cell epitope:antibody complex,qualitative binding|nuclear magnetic resonance (NMR),A B cell epitope qualitative binding to antibody assay that uses a nuclear magnetic resonance assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001703,,,,,,,,,,,,,,,,,,,A B cell epitope qualitative binding to antibody assay that uses a nuclear magnetic resonance assay.,IEDB,,,,,,NMR assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001662,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|nuclear magnetic resonance (NMR),,,,,,,,,,,,,,,,,,,,,,NMR assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000904,reporter cell line analyte detection bioassay,,An analyte assay in which a cell line whose growth is known to be affected by the presence of a specific type of material (the anlyte) is cultured in the presence of an input material (the evaluant) in order to detect presence of the analyte in the evaluant.,false,,,http://purl.obolibrary.org/obo/OBI_0000443,,,,,,,,,,,,,,,,,,,An analyte assay in which a cell line whose growth is known to be affected by the presence of a specific type of material (the anlyte) is cultured in the presence of an input material (the evaluant) in order to detect presence of the analyte in the evaluant.,IEDB,,,,,,reporter cell line analyte detection bioassay,,CTLL-2 cells were grown in the presence of hybridoma supernatants and their growth was monitored by a 3H-thymidine incorporation cell proliferation assay in order to detect IL-2 in the hybridoma supernatant.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0600024,,,,,,,,,,,,,,,,OBI:0000904,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,reporter cell line analyte detection bioassay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_1110107,cultured effector T cell population,effector T cell culture sample|culture of effector T cells,A cell culture including cells that have an effector T cell function,false,,,http://purl.obolibrary.org/obo/OBI_0001875,,,,effector T cell culture sample|culture of effector T cells,,,,,,,,,,,,,,,A cell culture including cells that have an effector T cell function,IEDB,,,,,,cultured effector T cell population,,A culture of cytotoxic CD8+ T cells.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110107,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cultured effector T cell population,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200003,logit-log curve fitting,,"A logit-log curve fitting is a curve fitting where first the limits y_0 an y_infty of y when x->0 and x->infinity, respectively, are estimated from the input data points (x_1, y_1), (x_2,y_2), ..., (x_n, y_n). Then a curve with equation log((y-y_0)/(y_infty-y))=a+b log(x) is obtained, where a and b are determined to optimize its fit to the input data points.",false,,,http://purl.obolibrary.org/obo/OBI_0200072,,http://purl.obolibrary.org/obo/OBI_0200174,,,,,,,,,,,,,,,,,"A logit-log curve fitting is a curve fitting where first the limits y_0 an y_infty of y when x->0 and x->infinity, respectively, are estimated from the input data points (x_1, y_1), (x_2,y_2), ..., (x_n, y_n). Then a curve with equation log((y-y_0)/(y_infty-y))=a+b log(x) is obtained, where a and b are determined to optimize its fit to the input data points.","ARTICLE: Plikaytis B.D. et al. (1991), J. Clin. Microbiol. 29(7): 1439-1448",,,,,"The above definition refers to the 'fully specified' logit-log model. The reduced form of this, when it is assumed that y_0=0, is named 'partially specified' logit-log model.",logit-log curve fitting,,"Typically used in an enzyme-linked immunosorbent assay (ELISA) to model the relationship between optical density (OD) and dilution. In this case OD_0 (also referred to OD_min) and OD_infty (also referred to OD_max) correspond to the theoretical OD of the assay at zero and infinite concentrations, respectively.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200003,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,logit-log curve fitting,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Ryan Brinkman|Melanie Courtot|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/GO_0032601,connective tissue growth factor production,,"The appearance of connective tissue growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of connective tissue growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,connective tissue growth factor production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032601,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,connective tissue growth factor production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032605,hepatocyte growth factor production,,"The appearance of hepatocyte growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of hepatocyte growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,hepatocyte growth factor production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032605,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,hepatocyte growth factor production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032608,interferon-beta production,,"The appearance of interferon-beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interferon-beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interferon-beta production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032608,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interferon-beta production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032606,type I interferon production,,"The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.",,,,,,,type I interferon production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032606,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,type I interferon production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032602,chemokine production,,"The appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,chemokine production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032602,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,chemokine production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032609,interferon-gamma production,,"The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon-gamma is also known as type II interferon.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon-gamma is also known as type II interferon.",,,,,,,interferon-gamma production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032609,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interferon-gamma production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032604,granulocyte macrophage colony-stimulating factor production,,"The appearance of granulocyte macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of granulocyte macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,granulocyte macrophage colony-stimulating factor production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032604,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,granulocyte macrophage colony-stimulating factor production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001401,protocol optimization design,,A study design where different protocols or protocol parameters are compared aims to find an optimized protocol,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,A study design where different protocols or protocol parameters are compared aims to find an optimized protocol,MO_934 optimization_design,,,,,,protocol optimization design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000186,,,,,,,,,,,,,,,,OBI:0001401,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,protocol optimization design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001709,assay measuring a binding constant of a B cell epitope:antibody complex,binding constant|binding assay,A B cell epitope recognition assay that quantitavely characterizes the binding of an antibody / BCR with a ligand by determining a binding constant. ,false,,,http://purl.obolibrary.org/obo/OBI_1110127|http://purl.obolibrary.org/obo/OBI_0001025,,,,,,,,,,,,,,,,,,,A B cell epitope recognition assay that quantitavely characterizes the binding of an antibody / BCR with a ligand by determining a binding constant. ,IEDB,,,,,,assay measuring a binding constant of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001709,,,,,,,,,,,,,,,,,,,,,,,,binding constant|binding assay,,,,,,,,,,,,,,,,,,,,,,assay measuring a binding constant of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0600033,cell permeabilization,,"A protocol application to permeabilize cell membranes, allowing molecules to more easily pass through the membrane than was possible prior to the protocol application",false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,"definition blessed by Jay, Alan, Randi",,"A protocol application to permeabilize cell membranes, allowing molecules to more easily pass through the membrane than was possible prior to the protocol application",OBI branch derived,,,,,need to add output cell has_quality permeable,cell permeabilization,,Electroporation of HeLa cells to allow transfection with pUC19.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CL_0000000,http://purl.obolibrary.org/obo/CL_0000000,,,OBI:0600033,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cell permeabilization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001038,Ruthenium structure mapping assay,,is a single-nucleotide-resolution nucleic acid structure mapping assay which uses Rhutenium as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,false,,,http://purl.obolibrary.org/obo/OBI_0001017,,http://purl.obolibrary.org/obo/OBI_0000441,,,,,,,,,,,,,,,,,is a single-nucleotide-resolution nucleic acid structure mapping assay which uses Rhutenium as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,RNAOntology,,,,,,Ruthenium structure mapping assay,,PMID:3016894,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001038,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Ruthenium structure mapping assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0200076,column submatrix extraction,,A column submatrix extraction is a submatrix extraction where all the rows of the input matrix are retained and selection only occurs on the columns.,false,,,http://purl.obolibrary.org/obo/OBI_0200074,,,,,,,,,,,,,,,,,,,A column submatrix extraction is a submatrix extraction where all the rows of the input matrix are retained and selection only occurs on the columns.,PERSON: Elisabetta Manduchi|PERSON: James Malone|PERSON: Melanie Courtot,,,,,,column submatrix extraction,,"When presented with the data from an expression microarray experiment in the form of a matrix, whose rows correspond to genes and whose columns correspond to samples, if one filters some of the samples out, the resulting data set corresponds to a column submatrix of the original set.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200076,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,column submatrix extraction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Melanie Courtot|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0001586,purified MHC direct binding assay measuring half life of a MHC:ligand complex using radioactivity detection,half life|purified MHC/direct/radioactivity|min,A purified MHC ligand half life of binding determination assay that uses radioactivity detection to measure direct ligand binding.,false,,,http://purl.obolibrary.org/obo/OBI_0001990|http://purl.obolibrary.org/obo/OBI_0001491,,,,,,,,,,,,,,,,,,,A purified MHC ligand half life of binding determination assay that uses radioactivity detection to measure direct ligand binding.,IEDB,,,,,,purified MHC direct binding assay measuring half life of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001586,,,,,,,,,,,,,,,,,,,,,,,,half life|purified MHC/direct/radioactivity|min,,,,,,,,,,,,,,,,,,,,,,purified MHC direct binding assay measuring half life of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0302837,decapitated organism,,decapitated organism is an organism which has had it's head removed,false,,,http://purl.obolibrary.org/obo/OBI_0000047|http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,decapitated organism is an organism which has had it's head removed,OBI Biomaterial,,,,,,decapitated organism,,"Ovarian development induced in decapitated female Culex pipiens pallens mosquitoes by infusion of physiological quantities of 20-hydroxyecdysone together with amino acids.
J Insect Physiol. 1998 May;44(5-6):525-528. PMID: 12770172",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302837,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,decapitated organism,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_1110095,blood harvesting,,A material separation where blood is taken from an organism.,false,,,http://purl.obolibrary.org/obo/OBI_0600014,,,,,,,,,,,,,,,,,,,A material separation where blood is taken from an organism.,IEDB,,,,,,blood harvesting,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000655,,,OBI:1110095,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,blood harvesting,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/GO_0050896,response to stimulus,,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.",false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.",,,,,,,response to stimulus,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0050896,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,response to stimulus,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000956,obsolete_handedness,,,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_handedness,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000228,,,,,,,,,,,,,,,,,,OBI:0000956,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_handedness,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/PATO_0002201,
http://purl.obolibrary.org/obo/OBI_0001585,cytometric bead array assay measuring epitope specific interleukin-7 production by T cells,IL-7 release|cytometric bead array,An assay of epitope specific interleukin-7 production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001587,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-7 production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific interleukin-7 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001585,,,,,,,,,,,,,,,,,,,,,,,,IL-7 release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific interleukin-7 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/GO_0030041,actin filament polymerization,,Assembly of actin filaments by the addition of actin monomers to a filament.,false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,Assembly of actin filaments by the addition of actin monomers to a filament.,,,,,,,actin filament polymerization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0030041,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,actin filament polymerization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0034343,type III interferon production,,"The appearance of type III interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon lambda is the only member of the type III interferon found so far.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of type III interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon lambda is the only member of the type III interferon found so far.",,,,,,,type III interferon production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0034343,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,type III interferon production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001190,epitope treatment experiment,decreased disease symptoms after treatment,an epitope intervention experiment that tests the ability of inducing an epitope immune response to treat an existing disease  in the host.,false,,,http://purl.obolibrary.org/obo/OBI_0001178,,,,,,,,,,,,,,,,,,,an epitope intervention experiment that tests the ability of inducing an epitope immune response to treat an existing disease  in the host.,,,,,,,epitope treatment experiment,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001190,,,,,,,,,,,,,,,,,,,,,,,,decreased disease symptoms after treatment,,,,,,,,,,,,,,,,,,,,,,epitope treatment experiment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_1110044,cultured PBMC cell population,PBMC cell culture sample,"A mixed cell population obtained by processing whole blood. The cells are characterized by having a similar density and are largely mononuclear cells (includes T cells, B cells, and other cell types).",false,,,http://purl.obolibrary.org/obo/OBI_0001875,,,,PBMC cell culture sample,,,,,,,,,,,,,,,"A mixed cell population obtained by processing whole blood. The cells are characterized by having a similar density and are largely mononuclear cells (includes T cells, B cells, and other cell types).",IEDB,,,,,,cultured PBMC cell population,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110044,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cultured PBMC cell population,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001274,genotyping by array assay,,An assay in which an array is used to detect polymorphisms in DNA samples,false,,,http://purl.obolibrary.org/obo/OBI_0000435,,,,,,,,,,,,,,,,,,,An assay in which an array is used to detect polymorphisms in DNA samples,EFO_0002767: genotyping by array,,,,,,genotyping by array assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0400148,,,,,,,,,,,,,,,OBI:0001274,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,genotyping by array assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Group: ArrayExpress production team,,
http://purl.obolibrary.org/obo/OBI_0200052,probabilistic algorithm,,A probabilistic algorithm is one which involves an element of probability or randomness in the transformation of the data.,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,A probabilistic algorithm is one which involves an element of probability or randomness in the transformation of the data.,PERSON: James Malone,,,,,,probabilistic algorithm,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200052,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,probabilistic algorithm,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0001957,hardware testing design,,"A study design that aims to compare different types of hardware for performance, reproducibility, accuracy and precision.",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A study design that aims to compare different types of hardware for performance, reproducibility, accuracy and precision.",MO_734 hardware_variation_design,,,,,,hardware testing design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001957,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,hardware testing design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jie Zheng,,
http://purl.obolibrary.org/obo/OBI_0200023,loess global transformation,,"A loess global transformation is a loess transformation where only one loess fitting is performed, utilizing one subset of (or possibly all of) the data points in the input so that there is only one resulting loess curve y=f(x) which is used for the transformation.",false,,,http://purl.obolibrary.org/obo/OBI_0200071,,,,,,,,,,,,,,,,,,,"A loess global transformation is a loess transformation where only one loess fitting is performed, utilizing one subset of (or possibly all of) the data points in the input so that there is only one resulting loess curve y=f(x) which is used for the transformation.",OTHER: Editor's generalization based on MGED Ontology term,,,,,,loess global transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200023,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,loess global transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Melanie Courtot|Elisabetta Manduchi|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0400102,waste tank,,"Part of the fluidics systems. In analyzers the sheath and sample fluid, once analyzed is dumped into a waste tank. The waste tank is where the fluids passing through the cytometer end up after the analysis is finished.",false,,,http://purl.obolibrary.org/obo/OBI_0000967,,,,,,,,,,,,,,,,,,,"Part of the fluidics systems. In analyzers the sheath and sample fluid, once analyzed is dumped into a waste tank. The waste tank is where the fluids passing through the cytometer end up after the analysis is finished.","Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253",,,,,,waste tank,,LSR2 waste tank,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000370,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400102,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,waste tank,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:John Quinn,,
http://purl.obolibrary.org/obo/OBI_0001627,country name,Specimen Collection Location - Country,A textual entity that denotes a geographic location that is a site or part of a site that is identified as a country in the political geography.,false,,,http://purl.obolibrary.org/obo/IAO_0000300,,,,,,,,,,,,,,,,,,,A textual entity that denotes a geographic location that is a site or part of a site that is identified as a country in the political geography.,Website: http://en.wikipedia.org/wiki/Country|NIAID GSCID-BRC metadata working group,http://purl.obolibrary.org/obo/GAZ_00000448,,,,,country name,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001627,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,country name,,,,,,Specimen Collection Location - Country,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001448,individual genetic characteristics comparison design,,"A study design where genotype, haplotype, or other individual genetic characteristics are compared.",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A study design where genotype, haplotype, or other individual genetic characteristics are compared.",MO_527 individual_genetic_characteristics_design,,,,,,individual genetic characteristics comparison design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000015,,,,,,,,,,,,,,,,OBI:0001448,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,individual genetic characteristics comparison design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/IAO_0000315,abstract,,A summary of the entire document that is substantially smaller than the document it summarizes.  It is about the document it summarizes.,false,,,http://purl.obolibrary.org/obo/IAO_0000314,,,,,,,,,,,,,,,,,,,A summary of the entire document that is substantially smaller than the document it summarizes.  It is about the document it summarizes.,,,,,,,abstract,,"The profusion of high-throughput instruments and the explosion of new results in the scientific literature, particularly in molecular biomedicine, is both a blessing and a curse to the bench researcher.   Even knowledgeable and experienced scientists can benefit from computational tools that help navigate this vast and rapidly evolving terrain. In this paper, we describe a novel computational approach to this challenge, a knowledge-based system that combines reading, reasoning and reporting methods to facilitate analysis of experimental data. Reading methods extract information from external resources, either by parsing structured data or biomedical language processing to extract information from unstructured data, and track knowledge provenance.  Reasoning methods enrich the knowledge that results from reading by, for example, noting two genes that are annotated to the same ontology term or database entry.  Reasoning is also used to combine all sources into a knowledge network that represents the integration of all sorts of relationships between a pair of genes, and to calculate a combined reliability score. Reporting methods combine the knowledge network with a congruent network constructed from experimental data and visualize the combined network in a tool that facilitates the knowledge-based analysis of that data.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000315,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000310,,,,,,,,,,,,,,,,abstract,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0600027,artificially induced cell membrane lysis,,"a material transformation to break the membranes of cells, releasing the cells contents; input=>cells; output=>cell_lysate",false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,"a material transformation to break the membranes of cells, releasing the cells contents; input=>cells; output=>cell_lysate",OBI branch derived,,,,,"---\nThere is a more general 'membrane lysis', which could apply to artificial membranes etc. For this general membrane encapsulated objects would need to be defined.",artificially induced cell membrane lysis,,http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&amp;list_uids=16080188&dopt=AbstractPlus; The destruction of cell membranes with detergent.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600027,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,artificially induced cell membrane lysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0001470,epitope specific interleukin-17F production by T cells,,A process of interleukin-17F production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/OBI_1110193|http://purl.obolibrary.org/obo/GO_0097088,,,,,,,,,,,,,,,,,Date: 2011-06-27; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of interleukin-17F production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific interleukin-17F production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001470,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific interleukin-17F production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000487,fourier transformation NMR instrument,,"In fourier transformation NMR, all frequencies in a spectrum are irradiated simultaneously with a radio frequency pulse. Following the pulse, the nuclei return to thermal equilibrium. A time domain emission signal is recorded by the instrument as the nuclei relax. A frequency domain spectrum is obtained by Fourier transformation.",false,,,http://purl.obolibrary.org/obo/OBI_0000566,,,,,,,,,,,,,,,,,NMR instrument,,"In fourier transformation NMR, all frequencies in a spectrum are irradiated simultaneously with a radio frequency pulse. Following the pulse, the nuclei return to thermal equilibrium. A time domain emission signal is recorded by the instrument as the nuclei relax. A frequency domain spectrum is obtained by Fourier transformation.",GROUP:<http://teaching.shu.ac.uk/hwb/chemistry/tutorials/molspec/nmr3.htm>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400284,,,,,,fourier transformation NMR instrument,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000487,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,fourier transformation NMR instrument,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000181,population,,"a population is a collection of individuals from the same taxonomic class living, counted or sampled at a particular site or in a particular area",false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,rem1: collection somehow always involve a selection process,,"a population is a collection of individuals from the same taxonomic class living, counted or sampled at a particular site or in a particular area",adapted from Oxford English Dictionnary,,,,,"1/28/2013, BP, on the call it was raised that we may want to switch to an external ontology for all populatin terms: 
http://code.google.com/p/popcomm-ontology/",population,,PMID12564891. Environ Sci Technol. 2003 Jan 15;37(2):223-8. Effects of historic PCB exposures on the reproductive success of the Hudson River striped bass population.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000181,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,population,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001788,detection of specific nucleic acids with complementary probes assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells,TNF release|RNA/DNA detection,An assay of epitope specific tumor necrosis factor superfamily cytokine production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001400,,,,,,,,,,,,,,,,,,,An assay of epitope specific tumor necrosis factor superfamily cytokine production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001788,,,,,,,,,,,,,,,,,,,,,,,,TNF release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001890,email address of specimen collector,Specimen Collector's email,An email address of the person collecting the specimen,false,,,http://purl.obolibrary.org/obo/IAO_0000429,,,,,,,,,,,,,,,,,,,An email address of the person collecting the specimen,NIAID GSCID-BRC metadata working group,,,,,,email address of specimen collector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001890,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,email address of specimen collector,,,,,,Specimen Collector's email,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/GO_0003964,RNA-directed DNA polymerase activity,,Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time.,false,,,http://purl.obolibrary.org/obo/GO_0003824,,,,,,,,,,,,,,,,,,,Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time.,,,,,,,RNA-directed DNA polymerase activity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0003964,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,RNA-directed DNA polymerase activity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001221,ChIP-chip by SNP array assay,,An assay where chromatin immunoprecipitation (ChIP) is used in combination with SNP microarray technology,false,,,http://purl.obolibrary.org/obo/OBI_0001248,,,,,,,,,,,,,,,,,,,An assay where chromatin immunoprecipitation (ChIP) is used in combination with SNP microarray technology,EFO_0002764 ChIP-chip by SNP array,,,,,,ChIP-chip by SNP array assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001204,,,,,,,,,,,,,,,OBI:0001221,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ChIP-chip by SNP array assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Group: ArrayExpress production team,,
http://purl.obolibrary.org/obo/OBI_0000921,labeled RNA extract,,a labeled specimen that is the output of a labeling process and has grain labeled RNA to be able to detect RNA in future experiments.,false,,,http://purl.obolibrary.org/obo/OBI_0001143,,,,,,,,,,,,,,,,,,,a labeled specimen that is the output of a labeling process and has grain labeled RNA to be able to detect RNA in future experiments.,Group: OBI group,,,,,"Need to find out if we consider labeled nucleotides still nucleotides. It is after consulting with ChEBI group.
Added duirng Mar 1, 2010 dev call",labeled RNA extract,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,http://purl.obolibrary.org/obo/CHEBI_33697,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000921,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,labeled RNA extract,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Group: OBI group,,
http://purl.obolibrary.org/obo/OBI_0200196,correlation study objective,,"A data transformation objective in which correlation is obtained (often measured as a correlation coefficient, ρ) which indicates the strength and direction of a relationship between two random variables.",false,,,http://purl.obolibrary.org/obo/OBI_0200166,,,,,,,,,,,,,,,,,,,"A data transformation objective in which correlation is obtained (often measured as a correlation coefficient, ρ) which indicates the strength and direction of a relationship between two random variables.",,,,,,,correlation study objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200196,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,correlation study objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Tina Boussard,,
http://purl.obolibrary.org/obo/OBI_0001575,assigning gene property based on phenotypic assessment,,"Interpreting data from assays that evaluate the qualities or dispositions inhering in an organism or organism part and comparing it to data from other organisms that have a defined genetic difference, and assigning a property to the product of the targeted gene as a result.",false,,,http://purl.obolibrary.org/obo/OBI_0000338,,,,,,,,,,,,,,,,,,,"Interpreting data from assays that evaluate the qualities or dispositions inhering in an organism or organism part and comparing it to data from other organisms that have a defined genetic difference, and assigning a property to the product of the targeted gene as a result.",Philly workshop 2011,,,,,,assigning gene property based on phenotypic assessment,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001575,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,assigning gene property based on phenotypic assessment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philly workshop 2011,,
http://purl.obolibrary.org/obo/OBI_0000400,display function,,A display function is a function to present information by translating that information through some lookup process into visual form.,false,,,http://purl.obolibrary.org/obo/OBI_0000392,,,,,,,,,,,,,,,,,,,A display function is a function to present information by translating that information through some lookup process into visual form.,,,,,,,display function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000400,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,display function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bill Bug|Daniel Schober|Frank Gibson|Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0001775,biological activity assay measuring epitope specific chemokine (C-C motif) ligand 19 production by T cells,CCL19/MIP-3b release|biological activity,A T cell epitope specific cytokine production assay that detects chemokine (C-C motif) ligand 19 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects chemokine (C-C motif) ligand 19 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific chemokine (C-C motif) ligand 19 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001775,,,,,,,,,,,,,,,,,,,,,,,,CCL19/MIP-3b release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific chemokine (C-C motif) ligand 19 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0600025,substance detection,,any protocol which results in the detection of a specified substance,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,http://purl.obolibrary.org/obo/OBI_0000441,,,,,,,,,,,,,,,,,any protocol which results in the detection of a specified substance,OBI branch derived,,,,,,substance detection,,the detection of phycoerytherin by means of flow cytometry,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000040,http://purl.obolibrary.org/obo/IAO_0000109,,,OBI:0600025,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,substance detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Kevin Clancy,,
http://purl.obolibrary.org/obo/GO_0036262,granulysin production,,"The appearance of granulysin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,"The appearance of granulysin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,granulysin production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0036262,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,granulysin production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001183,epitope protection from tumor challenge experiment,tumor burden after challenge,An epitope protection experiment in which the ability of the epitope to protect the host from developing tumors is assessed. ,false,,,http://purl.obolibrary.org/obo/OBI_0001184,,,,,,,,,,,,,,,,,,,An epitope protection experiment in which the ability of the epitope to protect the host from developing tumors is assessed. ,,,,,,,epitope protection from tumor challenge experiment,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001183,,,,,,,,,,,,,,,,,,,,,,,,tumor burden after challenge,,,,,,,,,,,,,,,,,,,,,,epitope protection from tumor challenge experiment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000424,transcription profiling assay,gene expression profiling|transcription profiling,"An assay which aims to provide information about gene expression and transcription activity using ribonucleic acids collected from a material entity using a range of techniques and instrument such as DNA sequencers, DNA microarrays, Northern Blot",false,,,http://purl.obolibrary.org/obo/OBI_0000070|http://purl.obolibrary.org/obo/OBI_0000443,,,,gene expression profiling,,,,,,,,,,,,,,,"An assay which aims to provide information about gene expression and transcription activity using ribonucleic acids collected from a material entity using a range of techniques and instrument such as DNA sequencers, DNA microarrays, Northern Blot",OBI,,,,,,transcription profiling assay,,Whole genome transcription profiling of Anaplasma phagocytophilum in human and tick host cells by tiling array analysis. BMC Genomics. 2008 Jul 31;9:364. PMID: 18671858,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000424,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,transcription profiling,transcription profiling assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0200018,loess group transformation one-channel,,A loess group transformation one-channel is a loess group transformation in the special case where the input is the result of an MA transformation applied to intensities from two related one-channel assays.,false,,,http://purl.obolibrary.org/obo/OBI_0200024,,,,,,,,,,,,,,,,,,,A loess group transformation one-channel is a loess group transformation in the special case where the input is the result of an MA transformation applied to intensities from two related one-channel assays.,OTHER: Editor's generalization based on MGED Ontology term,,,,,,loess group transformation one-channel,,A loess group transformation one-channel is a loess group transformation in the special case where the input is the result of an MA transformation applied to intensities from two related one-channel assays.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200018,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,loess group transformation one-channel,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0001744,intracellular cytokine staining assay measuring epitope specific interleukin-1 alpha production by T cells,IL-1a release|ICS,An assay of epitope specific interleukin-1 alpha production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001388,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-1 alpha production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-1 alpha production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001744,,,,,,,,,,,,,,,,,,,,,,,,IL-1a release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-1 alpha production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001040,current amplification function,,A current amplification function is an amplification function that increases the amplitude of a current.,false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,A current amplification function is an amplification function that increases the amplitude of a current.,,,,,,,current amplification function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001040,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,current amplification function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,EAGLE-I,,
http://purl.obolibrary.org/obo/OBI_0001392,in vivo assay measuring epitope specific T cell killing,cytotoxicity|in vivo assay,A T cell epitope specific killing assay that uses an in vivo cell mediated cell killing assay.,false,,,http://purl.obolibrary.org/obo/OBI_1110130,,,,,,,,,,,,,,,,,,,A T cell epitope specific killing assay that uses an in vivo cell mediated cell killing assay.,IEDB,,,,,,in vivo assay measuring epitope specific T cell killing,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001392,,,,,,,,,,,,,,,,,,,,,,,,cytotoxicity|in vivo assay,,,,,,,,,,,,,,,,,,,,,,in vivo assay measuring epitope specific T cell killing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_1110020,Immunization in vitro,,Process of administering an object playing the role of immunogen to a cell culture,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,Process of administering an object playing the role of immunogen to a cell culture,IEDB,,,,,,Immunization in vitro,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_1110094,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100060,http://purl.obolibrary.org/obo/OBI_0100060,,,OBI:1110020,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Immunization in vitro,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0002049,Illumina HiSeq 4000,HiSeq 4000,"A DNA sequencer manufactured by Illumina corporation, with two flow cell and a throughput of more than 400 Gb per day.",false,,,http://purl.obolibrary.org/obo/OBI_0400103,,,,HiSeq 4000,,,,,,,,,,,,,,,"A DNA sequencer manufactured by Illumina corporation, with two flow cell and a throughput of more than 400 Gb per day.",http://www.illumina.com/systems/hiseq-3000-4000.html,,,,,,Illumina HiSeq 4000,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002049,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Illumina HiSeq 4000,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Sagar Jain, Richard Scheuermann",,
http://purl.obolibrary.org/obo/OBI_0001955,competitive binding reference ligand role,,"A positive reference substance role that inheres in a material entity that is known to bind to a target entity, and that is realized in a competitive binding assay that has as specified input the target entity, an evaluant and the positive reference substance, where the binding of the evaluant to the target is measured based on the evaluant's ability to compete with the positive reference substance for binding to the target.",false,,,http://purl.obolibrary.org/obo/OBI_0000064,,,,,,,,,,,,,,,,,,,"A positive reference substance role that inheres in a material entity that is known to bind to a target entity, and that is realized in a competitive binding assay that has as specified input the target entity, an evaluant and the positive reference substance, where the binding of the evaluant to the target is measured based on the evaluant's ability to compete with the positive reference substance for binding to the target.",Bjoern Peters,,,,,,competitive binding reference ligand role,,The role of a radiolabeled peptide that is known to bind to the MHC molecule HLA-A*02:01 with high affinity when it is used in a competitive binding assay in which another peptide of interest is tested for its ability to outcompete binding of the labeled peptide in a dose dependent fashion.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001955,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,competitive binding reference ligand role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Bjoern Peters, Randi Vita, James A. Overton",,
http://purl.obolibrary.org/obo/OBI_0002013,nCounter Human V2 miRNA Expression array,,"An array which is manufacutred by NanoString Technologies. Built upon color-coded molecular barcodes technology, the array profiles miRNA with increased specificity and sensitivty than microarrays.",false,,,http://purl.obolibrary.org/obo/OBI_0001865,,,,,,,,,,,,,,,,,,,"An array which is manufacutred by NanoString Technologies. Built upon color-coded molecular barcodes technology, the array profiles miRNA with increased specificity and sensitivty than microarrays.",http://www.nanostring.com/media/pdf/PDS_nCounter_Human_v2_miRNA_Assay.pdf,,,,,,nCounter Human V2 miRNA Expression array,,"Kolbert, Christopher P., et al. ""Multi-platform analysis of microRNA expression measurements in RNA from fresh frozen and FFPE tissues."" PloS one 8.1 (2013): e52517. PMID:23382819",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002013,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,nCounter Human V2 miRNA Expression array,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"PERSON: Venkat Malladi, Chris Stoeckert, Jie Zheng, Alan Ruttenberg",,
http://purl.obolibrary.org/obo/OBI_0001099,immunoblot scanner,,A device that is used for the imaging of immunoblots.,false,,,http://purl.obolibrary.org/obo/OBI_0000398,,,,,,,,,,,,,,,,,,,A device that is used for the imaging of immunoblots.,PERSON: Erik Segerdell,,,,,,immunoblot scanner,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453|http://purl.obolibrary.org/obo/OBI_0000397,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001099,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,immunoblot scanner,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001904,sequencing service,,A service provides sequencing service which is the realization of some sequencing such as RNA and DNA sequencing in which the service provider role is realized.,false,,,http://purl.obolibrary.org/obo/OBI_0001528|http://purl.obolibrary.org/obo/OBI_0001547,,,,,,,,,,,,,,,,,,,A service provides sequencing service which is the realization of some sequencing such as RNA and DNA sequencing in which the service provider role is realized.,Adpated from 'DNA sequencing service',,,,,,sequencing service,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001904,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sequencing service,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,Person: Jie Zheng,,
http://purl.obolibrary.org/obo/OBI_0000526,preparative autosampler,,For preparative LC with injection of sample volumes ranging from L to mL ranges.,false,,,http://purl.obolibrary.org/obo/OBI_0000494,,,,,,,,,,,,,,,,,,,For preparative LC with injection of sample volumes ranging from L to mL ranges.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01062,,,,,,preparative autosampler,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000526,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,preparative autosampler,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001227,ELISPOT assay measuring epitope specific interleukin-6 production by T cells,IL-6 release|ELISPOT,An assay of epitope specific interleukin-6 production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001451,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-6 production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific interleukin-6 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001227,,,,,,,,,,,,,,,,,,,,,,,,IL-6 release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific interleukin-6 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001395,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-23 production by T cells,IL-23 release|RNA/DNA detection,An assay of epitope specific interleukin-23 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001363,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-23 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-23 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001395,,,,,,,,,,,,,,,,,,,,,,,,IL-23 release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-23 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000014,regulator role,regulator,a regulatory role involved with making and/or enforcing relevant legislation and governmental orders,false,,,http://purl.obolibrary.org/obo/OBI_0000017,,,,regulator,,,,,,,,,,,,,,,a regulatory role involved with making and/or enforcing relevant legislation and governmental orders,OBI,,,,,,regulator role,,Fact sheet - Regulating the companies The role of the regulator. Ofwat is the economic regulator of the water and sewerage industry in England and Wales.  http://www.ofwat.gov.uk/aptrix/ofwat/publish.nsf/Content/roleofregulator_factsheet170805,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000014,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,regulator role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0001472,specimen with known storage state,,A specimen for which it is known whether it has been subjected to storage of a specified type.,false,,,http://purl.obolibrary.org/obo/OBI_0100051,,,,,,,,,,,,,,,,,,,A specimen for which it is known whether it has been subjected to storage of a specified type.,MO_95 BiosourceType,,,,,,specimen with known storage state,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001472,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,specimen with known storage state,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001007,image creation,image acquisition,A planned process that captures an image of an object.,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,image acquisition,,,,,,,,,,,,,,,A planned process that captures an image of an object.,,,,,,,image creation,,Taking a polaroid picture of a patients skin lesion; Using a digital camera to take a picture of a gel,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000040,http://purl.obolibrary.org/obo/IAO_0000101,,,OBI:0001007,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,image creation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Jie Zheng,,
http://purl.obolibrary.org/obo/OBI_0000093,patient role,patient,a role which inheres in a person and is realized by the process of being under the care of a physician or health care provider,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,patient,,,,,,,,,,,,,"CDISC definition:  patient. Person under a physician's care for a particular disease or condition. NOTE: A subject in a clinical trial is not necessarily a patient, but a patient in a clinical trial is a subject. See also subject, trial subject, healthy volunteer. Often used interchangeably",,a role which inheres in a person and is realized by the process of being under the care of a physician or health care provider,"OBI, CDISC",,,,,,patient role,,a hospitalized person; a person with controlled diabetes; the patient's role http://www.fertilityjourney.com/testingAndDiagnosis/theRightDoctor/thePatientsRole/index.asp?C=55245395146924652778,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000093,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/NCBITaxon_9606,,,,,,,,,,,,,,,,,patient role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP:Role Branch,,
http://purl.obolibrary.org/obo/IAO_0000013,journal article,,a report that is published in a journal,false,,,http://purl.obolibrary.org/obo/IAO_0000088,,,,,,,,,,,,,,,,,,,a report that is published in a journal,group:OBI|OBI_0000159,,,,,,journal article,,"Examples are articles published in the journals, Nature and Science. The content can often be cited by reference to a paper based encoding, e.g.  Authors, Title of article, Journal name, date or year of publication, volume and page number.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000013,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,journal article,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Alan Ruttenberg|person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/IAO_0000065,software interpreter,,A software interpreter is a software application that executes some specified input software. ,false,,,http://purl.obolibrary.org/obo/IAO_0000064,,,,,,,,,,,,,,,,,,,A software interpreter is a software application that executes some specified input software. ,OBI_0000199|group:OBI,,,,,"Do we care? Jennifer: Yes, there was a particular version of R that had a bug and it was fixed later. That would imply that we mean specific version of an interpreter. So an instance of this would be a particular version of the interpreter",software interpreter,,"R program, Perl interpreter, Java virtual machine",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000065,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,software interpreter,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Alan Ruttenberg|person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0001006,CMCT structure mapping assay,single nucleotide resolution mapping assay using CMCT probe,a single-nucleotide-resolution nucleic acid structure mapping assay which uses CMCT as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,false,,,http://purl.obolibrary.org/obo/OBI_0001017,,http://purl.obolibrary.org/obo/OBI_0000441,,single nucleotide resolution mapping assay using CMCT probe,,,,,,,,,,,,,,,a single-nucleotide-resolution nucleic acid structure mapping assay which uses CMCT as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,RNA ontology,,,,,,CMCT structure mapping assay,,PMID:2422386 and PMID:2446263,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001006,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CMCT structure mapping assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000794,transcription factor binding site,,PLace_holder for sequence ontology term,false,,,http://purl.obolibrary.org/obo/OBI_0000905,,,,,,,,,,,,,,,,,,,,SO:0000235,,,,,,transcription factor binding site,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000002,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000794,,,,,,,,,,,,,,,,,,PLace_holder for sequence ontology term,,,,,,,,,,,,,,,,,,,,,,,,,,,,transcription factor binding site,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001356,detection of specific nucleic acids with complementary probes assay measuring epitope specific interferon-beta production by T cells,IFNb release|RNA/DNA detection,An assay of epitope specific interferon-beta production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001390,,,,,,,,,,,,,,,,,,,An assay of epitope specific interferon-beta production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interferon-beta production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001356,,,,,,,,,,,,,,,,,,,,,,,,IFNb release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interferon-beta production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/CHEBI_29191,hydroxyl,,An oxygen radical that has formula HO.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,An oxygen radical that has formula HO.,,,,,,,hydroxyl,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:29191,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,hydroxyl,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0048869,cellular developmental process,,A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.,false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.,,,,,,,cellular developmental process,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0048869,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,cellular developmental process,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001387,genotyping by array design,,"A study design that classifies an individual or group of individuals on the basis of alleles, haplotypes, SNPs using microarray technology.",false,,,http://purl.obolibrary.org/obo/OBI_0001444,,,,,,,,,,,,,,,,,,,"A study design that classifies an individual or group of individuals on the basis of alleles, haplotypes, SNPs using microarray technology.",MO_560 genotyping_design,,,,,,genotyping by array design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001387,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,genotyping by array design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001875,cultured immune cell population,immune cell culture sample,a cultured cell population comprised of a single type of immune system cell,false,,,http://purl.obolibrary.org/obo/OBI_0100060,,,,immune cell culture sample,,,,,,,,,,,,,,,a cultured cell population comprised of a single type of immune system cell,PERSON:Matthew Brush,,,,,"MHB 3-5-13: created as a (temporary) organizational class to organize IEDB immune cultured cell population types. These were all previously labled as 'cell cultures' - and relabeld here as 'cultured cell populations' since a CLO alignment outcome was to use the term 'cell culture' to refer to cultured cells + media.  Consult with BP as to whether this organizational class is useful and if so, how to define it.  Also check whether the intent was to represent cell populations rather than cell cultures.",cultured immune cell population,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001875,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cultured immune cell population,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_0002051,in vivo assay measuring B cell epitope specific protection from infectious challenge based on pathogen burden,pathogen burden after challenge|in vivo assay,A B cell epitope in vivo intervention experiment that uses a protection from challenge in vivo intervention experiment based on pathogen burden.,false,,,http://purl.obolibrary.org/obo/OBI_0001710,,,,,,,,,,,,,,,,,,,A B cell epitope in vivo intervention experiment that uses a protection from challenge in vivo intervention experiment based on pathogen burden.,IEDB,,,,,,in vivo assay measuring B cell epitope specific protection from infectious challenge based on pathogen burden,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001982,,,,,,,,,,,,,,,,OBI:0002051,,,,,,,,,,,,,,,,,,,,,,,,pathogen burden after challenge|in vivo assay,,,,,,,,,,,,,,,,,,,,,,in vivo assay measuring B cell epitope specific protection from infectious challenge based on pathogen burden,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001065,stereo microscope,,An optical microscope that uses two separate optical paths with two objectives and two eyepieces to provide slightly different viewing angles to the left and right eyes.,false,,,http://purl.obolibrary.org/obo/OBI_0000940,,,,,,,,,,,,,,,,,,,An optical microscope that uses two separate optical paths with two objectives and two eyepieces to provide slightly different viewing angles to the left and right eyes.,http://en.wikipedia.org/wiki/Optical_microscope#Stereo_microscope,,,,,,stereo microscope,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001065,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,stereo microscope,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0000571,manufacturer role,,Manufacturer role is a role which inheres in a person or organization and which is realized by a manufacturing process.,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,,,Manufacturer role is a role which inheres in a person or organization and which is realized by a manufacturing process.,OBI,,,,,,manufacturer role,,"With respect to The Accuri C6 Flow Cytometer System, the organization Accuri bears the role manufacturer role.  With respect to a transformed line of tissue culture cells derived by a specific lab, the lab whose personnel isolated the cll line bears the role manufacturer role.  With respect to a specific antibody produced by an individual scientist, the scientist who purifies, characterizes and distributes the anitbody bears the role manufacturer role.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000571,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,manufacturer role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP:  Role Branch,,
http://purl.obolibrary.org/obo/OBI_1110160,ELISA measuring epitope specific interleukin-12 production by T cells,IL-12 release|ELISA,An assay of epitope specific interleukin-12 production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001391,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-12 production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific interleukin-12 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110160,,,,,,,,,,,,,,,,,,,,,,,,IL-12 release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific interleukin-12 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001944,sequence annotation,,A planned process that identifies and reports sequence features (e.g. protein coding regions) in sequence data.,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,,,A planned process that identifies and reports sequence features (e.g. protein coding regions) in sequence data.,NIAID GSCID-BRC metadata working group,,,,,,sequence annotation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000973,http://purl.obolibrary.org/obo/OBI_0000905,,,OBI:0001944,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sequence annotation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Jie Zheng, Chris Stoeckert",,
http://purl.obolibrary.org/obo/OBI_0200185,scaling data transformation,,A scaling data transformation is a data transformation that has objective scaling.,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,A scaling data transformation is a data transformation that has objective scaling.,PERSON: James Malone,,,,,,scaling data transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200185,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,scaling data transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0000484,NMR sample holder,,"An NMR sample holder is the part of an NMR instrument, which carries the NMR probe,sample tube and the nmr sample.",false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,NMR device,,"An NMR sample holder is the part of an NMR instrument, which carries the NMR probe,sample tube and the nmr sample.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400212,,,,,,NMR sample holder,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000484,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NMR sample holder,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/PATO_0000047,biological sex,,An organismal quality inhering in a bearer by virtue of the bearer's ability to undergo sexual reproduction in order to differentiate the individuals or types involved.,false,,,http://purl.obolibrary.org/obo/PATO_0001995,,,,,,,,,,,,,,,,,,,An organismal quality inhering in a bearer by virtue of the bearer's ability to undergo sexual reproduction in order to differentiate the individuals or types involved.,,,,,,,biological sex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0000047,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,biological sex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001369,wild type allele information,,"an allele information that is about the allele found most frequently in natural populations, or in standard laboratory stocks for a given organism.",false,,,http://purl.obolibrary.org/obo/OBI_0001352,,,,,,,,,,,,,,,,,,,"an allele information that is about the allele found most frequently in natural populations, or in standard laboratory stocks for a given organism.",MO_605 genotype,,,,,"discussed on San Diego OBI workshop, March 2011",wild type allele information,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001369,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,wild type allele information,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_1110039,T2 cell line,,A human T-B lymphoblastoid hybrid cell line,false,,,http://purl.obolibrary.org/obo/CLO_0009828,,,,,,,,,,,,,,,,,,,A human T-B lymphoblastoid hybrid cell line,http://www.atcc.org/ATCCAdvancedCatalogSearch/ProductDetails/tabid/452/Default.aspx?ATCCNum=CRL-1992&Template=cellBiology|IEDB,,,,,,T2 cell line,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110039,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,T2 cell line,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0600029,isolation of cell culture supernatant,,a protocol which results in the separation of supernatant material from a cell culture,false,,,http://purl.obolibrary.org/obo/OBI_0600014,,http://purl.obolibrary.org/obo/OBI_0000681,,,,,,,,,,,,,,,,,a protocol which results in the separation of supernatant material from a cell culture,OBI branch derived,,,,,This does not apply to the case where the cells are lysed,isolation of cell culture supernatant,,Pouring out a portion of the fluid part of an adherant cell culture growing in a flask.; The centrifugation of a T cell culture followed by aspiration of the supernatant while the cellular pellet remains in the centrifuge tube.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600029,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,isolation of cell culture supernatant,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0400055,inFlux Analyzer,,"The inFlux Analyzer is a flow_cytometer_analyser manufactured by Cytopeia. It is a digital machine, with these laser options: Coherent 70, 90, 300 series water cooled lasers, solid state UV 355nm, Violet 408nm, Violet-Blue 479nm, Blue-488nm, Green-531nm, Red-635nm, Red-647nm. Filters and PMTs are used for all parameters (including forward light scatter), and up to 12 PMTs can be included. The Influx analyser can be used to measure the properties of individual cells.",false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,,,,,,,,,,,,,,,,"The inFlux Analyzer is a flow_cytometer_analyser manufactured by Cytopeia. It is a digital machine, with these laser options: Coherent 70, 90, 300 series water cooled lasers, solid state UV 355nm, Violet 408nm, Violet-Blue 479nm, Blue-488nm, Green-531nm, Red-635nm, Red-647nm. Filters and PMTs are used for all parameters (including forward light scatter), and up to 12 PMTs can be included. The Influx analyser can be used to measure the properties of individual cells.",http://www.cytopeia.com/analyzer.htm,,,,,,inFlux Analyzer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400055,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,inFlux Analyzer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0000478,column connector,,"A device that connects two or more columns together in a functional way with leak-tight connection, low dead volume, low thermal mass and high inertness.",false,,,http://purl.obolibrary.org/obo/OBI_0000048,,,,,,,,,,,,,,,,,chromatography device,,"A device that connects two or more columns together in a functional way with leak-tight connection, low dead volume, low thermal mass and high inertness.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01236,,,,,,column connector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000478,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,column connector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/BFO_0000146,two-dimensional continuant fiat boundary,,,false,,,http://purl.obolibrary.org/obo/BFO_0000140,,,,,,,TwoDimensionalContinuantFiatBoundary,2d-cf-boundary,,,,,,,,,,,,,,,,,,two-dimensional continuant fiat boundary,a two-dimensional continuant fiat boundary (surface) is a self-connected fiat surface whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [033-001]),,,,,,,,,(iff (TwoDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (TwoDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [033-001] ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000146,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,two-dimensional continuant fiat boundary,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000796,purification objective,isolation objective,"The objective to separate a material entity into different compositions of which one or more have are purified fractions that contain higher concentration of a desired component, while others contain impurities and are not of interest",false,,,http://purl.obolibrary.org/obo/OBI_0000681,,,,isolation objective,,,,,,,,,,,,,"10/14/09,  BP: This should be linked to the 'purified' 'currently conferred quality",,"The objective to separate a material entity into different compositions of which one or more have are purified fractions that contain higher concentration of a desired component, while others contain impurities and are not of interest",BP,,,,,,purification objective,,the objective to obtain a pure fraction of a specific peptide when running an HPLC on a crude synthesis of peptides.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000796,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,purification objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001711,in vivo assay measuring B cell epitope specific disease exacerbation,disease exacerbation|in vivo assay,An efficacy of B cell epitope intervention experiment that uses a disease exacerbation in vivo intervention experiment.,false,,,http://purl.obolibrary.org/obo/OBI_0001698,,,,,,,,,,,,,,,,,,,An efficacy of B cell epitope intervention experiment that uses a disease exacerbation in vivo intervention experiment.,IEDB,,,,,,in vivo assay measuring B cell epitope specific disease exacerbation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001711,,,,,,,,,,,,,,,,,,,,,,,,disease exacerbation|in vivo assay,,,,,,,,,,,,,,,,,,,,,,in vivo assay measuring B cell epitope specific disease exacerbation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000237,antigen role,,Antigen is a role played by material which when introduced into an immune-competent organism causes an immune response,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,9Mar09 waiting for discussion with immunology terms,,Antigen is a role played by material which when introduced into an immune-competent organism causes an immune response,OBI,,,,,"An antigen is a substance that prompts the generation of antibodies and can cause an immune response.  Wikipedia  http://en.wikipedia.org/wiki/Antigen. In the strict sense, immunogens are those substances that elicit a response from the immune system, whereas antigens are defined as substances that bind to specific antibodies. Not all antigens produce an immunogenic response, but all immunogens are antigens",antigen role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000237,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,antigen role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Role Branch,,
http://purl.obolibrary.org/obo/OBI_0000392,information processor function,data processor function,"An information processor function is a function that converts information from one form to another, by a lossless process or an extraction process.",false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,data processor function,,,,,,,,,,,,,,,"An information processor function is a function that converts information from one form to another, by a lossless process or an extraction process.",,,,,,,information processor function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000453|http://purl.obolibrary.org/obo/OBI_0000455,,,,,,,,,,,,,,,,OBI:0000392,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,information processor function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Frank Gibson,,
http://purl.obolibrary.org/obo/OBI_0200070,edge weighting,,"Edge weighting is the substitution or transformation of edge length using numerical data.  Data input include a symmetric adjacency matrix for a network and a second data set, for example a list of interactor pairs and a confidence score associated with the experimental detection of each pair's interaction.  Each element in the adjacency matrix is transformed or replaced with the corresponding number in the second data set.  Output data are a modified adjacency matrix reflecting the transformed state of the network.",false,,,http://purl.obolibrary.org/obo/OBI_0200080,,,,,,,,,,,,,,,,,"was classified under algorithm class which is not acceptable super-class
TO BE DEALT WITH STILL BY RICHARD.  JAMES",,"Edge weighting is the substitution or transformation of edge length using numerical data.  Data input include a symmetric adjacency matrix for a network and a second data set, for example a list of interactor pairs and a confidence score associated with the experimental detection of each pair's interaction.  Each element in the adjacency matrix is transformed or replaced with the corresponding number in the second data set.  Output data are a modified adjacency matrix reflecting the transformed state of the network.",editor,,,,,,edge weighting,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200070,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,edge weighting,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Tina Hernandez-Boussard,,
http://purl.obolibrary.org/obo/OBI_0200157,data vector reduction objective,,"Data vector reduction is a data transformation objective in which k m-dimensional input vectors are reduced to j m-dimensional output vectors, where j is smaller than k.",false,,,http://purl.obolibrary.org/obo/OBI_0200166,,,,,,,,,,,,,,,,,,,"Data vector reduction is a data transformation objective in which k m-dimensional input vectors are reduced to j m-dimensional output vectors, where j is smaller than k.",PERSON: Richard H. Scheuermann,,,,,,data vector reduction objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200157,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,data vector reduction objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Richard H. Scheuermann|James Malone,,
http://purl.obolibrary.org/obo/OBI_0002009,Mouse 3x720K Whole Genome CGH Tiling Array,Nimblegen Mouse 3x720K Whole Genome CGH Tiling Array,"A tiling array which is manufactured by the Nimblegen corporation. Built to analyze DNA sequence copy number by comparative genomic hybridization for mouse DNA against 3x720,000 features.",false,,,http://purl.obolibrary.org/obo/OBI_0001307,,,,Nimblegen Mouse 3x720K Whole Genome CGH Tiling Array,,,,,,,,,,,,,,,"A tiling array which is manufactured by the Nimblegen corporation. Built to analyze DNA sequence copy number by comparative genomic hybridization for mouse DNA against 3x720,000 features.",http://www.nimblegen.com/downloads/support/05434483001_NG_CGHLOH_UGuide_v9p1.pdf,,,,,,Mouse 3x720K Whole Genome CGH Tiling Array,,"Wartman, Lukas D., et al. ""Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progression."" The Journal of clinical investigation 121.4 (2011): 1445. PMID:21436584",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002009,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Mouse 3x720K Whole Genome CGH Tiling Array,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"PERSON: Venkat Malladi, Chris Stoeckert, Jie Zheng, Alan Ruttenberg",,
http://purl.obolibrary.org/obo/IAO_0000079,density plot,,A density plot is a report graph which is a graphical representation of data where the tint of a particular pixel corresponds to some kind of function corresponding the the amount of data points relativelly with their distance from the the pixel.,false,,,http://purl.obolibrary.org/obo/IAO_0000038,,,,,,,,,,,,,,,,,,,A density plot is a report graph which is a graphical representation of data where the tint of a particular pixel corresponds to some kind of function corresponding the the amount of data points relativelly with their distance from the the pixel.,OBI_0000179|group:Flow Cytometry community,,,,,,density plot,,Density plot of SSC-H and FSC-H.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000002,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000079,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,density plot,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Allyson Lister|person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0000015,biological feature identification objective,,Biological_feature_identification_objective is an objective role carried out by the proposition defining the aim of a study designed to examine or characterize a particular biological feature.,false,,,http://purl.obolibrary.org/obo/IAO_0000005,,,,,,,,,,,,,,,,,,,Biological_feature_identification_objective is an objective role carried out by the proposition defining the aim of a study designed to examine or characterize a particular biological feature.,,,,,,,biological feature identification objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000015,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,biological feature identification objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0000056,notified body role,notified body,Notified body is regulator of consumables and medical devices charged by the Competent Authority with verifying compliance of medical devices (not drugs) with the applicable Essential Requirements stated in the Medical Device Directive,false,,,http://purl.obolibrary.org/obo/OBI_0000273,,,,notified body,,,,,,,,,,,,,,,Notified body is regulator of consumables and medical devices charged by the Competent Authority with verifying compliance of medical devices (not drugs) with the applicable Essential Requirements stated in the Medical Device Directive,"OBI, CDISC",,,,,"Notified Body (NB). A private institution charged by the Competent Authority with verifying compliance of medical devices (not drugs) with the applicable Essential Requirements stated in the Medical Device Directive. This process, called Conformity Assessment, has EU-wide validity once completed by the NB.",notified body role,,The role of notified bodies presentation: http://ec.europa.eu/enterprise/electr_equipment/emc/revision/notified_bodies.pdf,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000056,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,notified body role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0000802,prothrombin time assay,,"The prothrombin time is an assay most commonly measured using blood plasma. Blood is drawn into a test tube containing liquid citrate, which acts as an anticoagulant by binding the calcium in a sample. The blood is mixed, then centrifuged to separate blood cells from plasma. In newborns, whole blood is used. The plasma is analyzed by a biomedical scientist on an automated instrument at 37 degrees C, which takes a sample of the plasma. An excess of calcium is added (thereby reversing the effects of citrate), which enables the blood to clot again. For an accurate measurement the proportion of blood to citrate needs to be fixed; many laboratories will not perform the assay if the tube is underfilled and contains a relatively high concentration of citrate. If the tube is underfilled or overfilled with blood, the standardized dilution of 1 part anticoagulant to 9 parts whole blood is no longer valid. For the prothrombin time test the appropriate sample is the blue top tube, or sodium citrate tube, which is a liquid anticoagulant. Tissue factor (also known as factor III or thromboplastin) is added, and the time the sample takes to clot is measured optically. Some laboratories use a mechanical measurement, which eliminates interferences from lipemic and icteric samples. The prothrombin ratio is the prothrombin time for a patient, divided by the result for control plasma.",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,,"The prothrombin time is an assay most commonly measured using blood plasma. Blood is drawn into a test tube containing liquid citrate, which acts as an anticoagulant by binding the calcium in a sample. The blood is mixed, then centrifuged to separate blood cells from plasma. In newborns, whole blood is used. The plasma is analyzed by a biomedical scientist on an automated instrument at 37 degrees C, which takes a sample of the plasma. An excess of calcium is added (thereby reversing the effects of citrate), which enables the blood to clot again. For an accurate measurement the proportion of blood to citrate needs to be fixed; many laboratories will not perform the assay if the tube is underfilled and contains a relatively high concentration of citrate. If the tube is underfilled or overfilled with blood, the standardized dilution of 1 part anticoagulant to 9 parts whole blood is no longer valid. For the prothrombin time test the appropriate sample is the blue top tube, or sodium citrate tube, which is a liquid anticoagulant. Tissue factor (also known as factor III or thromboplastin) is added, and the time the sample takes to clot is measured optically. Some laboratories use a mechanical measurement, which eliminates interferences from lipemic and icteric samples. The prothrombin ratio is the prothrombin time for a patient, divided by the result for control plasma.",WEB:http://en.wikipedia.org/wiki/Prothrombin_time@2009/10/06,,,,,2009/10/18 Alan Ruttenberg. This assay was added during the fucoidan use case exercise but still needs to be fleshed out. Only the AT-III assay has more carefully specified inputs and outputs,prothrombin time assay,,"PMID:19696660#The prothrombin time (PT) was quantitatively determined using RecombiPlasTin (Instrumentation Laboratory Company, Lexington, Massachusetts, USA).",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000802,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,prothrombin time assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/UO_0000280,rate unit,,A unit which represents a standard measurement occurrence of a process per unit time.,false,,,http://purl.obolibrary.org/obo/IAO_0000003,,,,,,,,,,,,,,,,,,,A unit which represents a standard measurement occurrence of a process per unit time.,,,,,,,rate unit,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UO:0000280,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uo.owl,,,,,,,,,,,,,,,,,,,rate unit,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_1110181,BrdU assay measuring epitope specific proliferation of T cells,proliferation|BrdU,A T cell epitope specific proliferation assay performed on cells in vitro that uses a BrdU incorporation assay.,false,,,http://purl.obolibrary.org/obo/OBI_0002071,,,,,,,,,,,,,,,,,,,A T cell epitope specific proliferation assay performed on cells in vitro that uses a BrdU incorporation assay.,IEDB,,,,,,BrdU assay measuring epitope specific proliferation of T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110181,,,,,,,,,,,,,,,,,,,,,,,,proliferation|BrdU,,,,,,,,,,,,,,,,,,,,,,BrdU assay measuring epitope specific proliferation of T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001670,RNA protection assay,RPA; RNAse protection assay,"RPA is a technique to assess the presence and estimate abundance of transcript species by first creating an homo or heteroduplex by adding a specific, complementary sequence to the sequence of interest and then exposing the mixture of ribonuclease, which will degrade only single stranded molecules. A detection step will reveal if the sample contained a sequence of interest.",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,RPA; RNAse protection assay,,,,,,,,,,,,,,,"RPA is a technique to assess the presence and estimate abundance of transcript species by first creating an homo or heteroduplex by adding a specific, complementary sequence to the sequence of interest and then exposing the mixture of ribonuclease, which will degrade only single stranded molecules. A detection step will reveal if the sample contained a sequence of interest.",adapted from wikipedia + PMID:16491611,,,,,,RNA protection assay,,"Absolute concentrations of mRNA for type I and type VI collagen in the canine meniscus in normal and ACL-deficient knee joints obtained by RNase protection assay.
Wildey GM, Billetz AC, Matyas JR, Adams ME, McDevitt CA.
J Orthop Res. 2001 Jul;19(4):650-8.
PMID: 11518275",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001670,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,RNA protection assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra; Marcus Chibucos,,
http://purl.obolibrary.org/obo/OBI_0000841,subject agrees they understand informed consent document,,A process in which a subject receives an informed consent document and agrees that they have understood it,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,,A process in which a subject receives an informed consent document and agrees that they have understood it,,,,,,"09/28/2009 Alan Ruttenberg. There's a need for a general process like this in IAO - document and person in, signed document (and associated obligations, rights, out",subject agrees they understand informed consent document,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000810,OBI:0000841,http://purl.obolibrary.org/obo/OBI_0000810,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,subject agrees they understand informed consent document,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0001515,material maintenance service,,"A material processing service in which a service provider makes physical modifications to a specified input material, such that at least one of the specified outputs of this process is a modified version of a specified input material.|Here we need to go back to the defintoin of storage process. It has object specification which is material maintenance. Not necessareley a material maintenance is needed in a storage process. ",false,,,http://purl.obolibrary.org/obo/OBI_0001528,,,,,,,,,,,,,,,,,,,"A material processing service in which a service provider makes physical modifications to a specified input material, such that at least one of the specified outputs of this process is a modified version of a specified input material.",PERSON: Matthew Brush,,,,,,material maintenance service,,model organism colony maintanance,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001515,,,,,,,,,,,,,,,,,,Here we need to go back to the defintoin of storage process. It has object specification which is material maintenance. Not necessareley a material maintenance is needed in a storage process. ,,,,,,,,,,,,,,,,,,,,,,,,,,,,material maintenance service,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Carlo Torniai|PERSON: Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_0001308,biological activity assay measuring epitope specific IP-10 production by T cells,CXCL10/IP-10 release|biological activity,A T cell epitope specific cytokine production assay that detects IP-10 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects IP-10 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific IP-10 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001308,,,,,,,,,,,,,,,,,,,,,,,,CXCL10/IP-10 release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific IP-10 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/GO_0032906,transforming growth factor beta2 production,,"The appearance of transforming growth factor-beta2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of transforming growth factor-beta2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,transforming growth factor beta2 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032906,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,transforming growth factor beta2 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032905,transforming growth factor beta1 production,,"The appearance of transforming growth factor-beta1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of transforming growth factor-beta1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,transforming growth factor beta1 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032905,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,transforming growth factor beta1 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032907,transforming growth factor beta3 production,,"The appearance of transforming growth factor-beta3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of transforming growth factor-beta3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,transforming growth factor beta3 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032907,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,transforming growth factor beta3 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/IAO_0000429,email address,,,false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,,,,,,,,,,,,,,,,,,,,,,"Alan Ruttenberg 1/3/2012 - Provisional id, see issue at http://code.google.com/p/information-artifact-ontology/issues/detail?id=130&thanks=130&ts=1325636583",email address,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000429,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,email address,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Chris Stoeckart|Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0600040,synthesis,synthesize,the construction of a biomaterial from simpler biomaterials,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,synthesize,,,,,,,,,,,,,,,the construction of a biomaterial from simpler biomaterials,OBI branch derived,,,,,This probably needs breaking down into more specific applications. The example given is already covered in reverse_transcription,synthesis,,making cDNA from nucleotides using RNA as a template,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_23367,http://purl.obolibrary.org/obo/CHEBI_23367,,,OBI:0600040,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,synthesis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Kevin Clancy,,
http://purl.obolibrary.org/obo/OBI_0400095,short pass filter,,A short pass filter is an optical filter that passes low wavelengths of light but attenuates (or reduces) wavelengths higher than the cutoff frequency. A short pass filter with a cutoff of 500 nm would pass all wavelengths less than 500 nm.,false,,,http://purl.obolibrary.org/obo/OBI_0400079,,,,,,,,,,,,,,,,,,,A short pass filter is an optical filter that passes low wavelengths of light but attenuates (or reduces) wavelengths higher than the cutoff frequency. A short pass filter with a cutoff of 500 nm would pass all wavelengths less than 500 nm.,http://en.wikipedia.org/wiki/Low-pass_filter,,,,,,short pass filter,,620 SP filter,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400095,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,short pass filter,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0000936,obsolete_material access provider role,,a service provider role which is realized by a servicer provider organization performing access to some material,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,a service provider role which is realized by a servicer provider organization performing access to some material,OBI,,,,,"obsolete during the San Diego workshop, March 2011
The reason is that we decided to pursue a different modeling approach for services keeping just the 'service consumer' and 'service provider' roles and differentiate just at the level of planned process offered a s service.",obsolete_material access provider role,,A person or organization who provides access to a DNA sequencer.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,OBI:0000936,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_material access provider role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0001336,quality control testing design,,A study design in which some aspects of the experiment is quality controlled for the purposes of quality assurance.,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,A study design in which some aspects of the experiment is quality controlled for the purposes of quality assurance.,MO_981 quality_control_testing_design,,,,,,quality control testing design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001336,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,quality control testing design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000953,processed specimen,,A specimen that has been intentionally physically modified.|A tissue sample that has been sliced and stained for a histology study.,false,,,http://purl.obolibrary.org/obo/OBI_0100051|http://purl.obolibrary.org/obo/OBI_0000047,,,,,,,,,,,,,,,,,,,A specimen that has been intentionally physically modified.,Bjoern Peters,,,,,,processed specimen,,"A tissue sample that has been sliced and stained for a histology study.
A blood specimen that has been centrifuged to obtain the white blood cells.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000953,,,,,,,,,,,,,,,,,,A tissue sample that has been sliced and stained for a histology study.,,,,,,,,,,,,,,,,,,,,,,,,,,,,processed specimen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0200045,single linkage hierarchical clustering,,"A single linkage hierarchical clustering is an agglomerative hierarchical clustering which generates successive clusters based on a distance measure, where the distance between two clusters is calculated as the minimum distance between objects from the first cluster and objects from the second cluster.",false,,,http://purl.obolibrary.org/obo/OBI_0200154,,,,,,,,,,,,,,,,,,,"A single linkage hierarchical clustering is an agglomerative hierarchical clustering which generates successive clusters based on a distance measure, where the distance between two clusters is calculated as the minimum distance between objects from the first cluster and objects from the second cluster.",PERSON: Elisabetta Manduchi,,,,,,single linkage hierarchical clustering,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200045,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,single linkage hierarchical clustering,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0200187,sequence analysis data transformation,,A sequence analysis data transformation is a data transformation that has objective sequence analysis and has the aim of analysing ordered biological data for sequential patterns.,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,A sequence analysis data transformation is a data transformation that has objective sequence analysis and has the aim of analysing ordered biological data for sequential patterns.,EDITOR,,,,,,sequence analysis data transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200187,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sequence analysis data transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/IAO_0000316,introduction to a publication about an investigation,introduction,A part of a publication about an investigation that is about the objective specification (why the investigation is being done),false,,,http://purl.obolibrary.org/obo/IAO_0000314,,,,introduction,,,,,,,,,,,,,,,A part of a publication about an investigation that is about the objective specification (why the investigation is being done),,,,,,,introduction to a publication about an investigation,,Section labelled 'introduction' of a typical scientific journal article,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000316,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000005,,,,,,,,,,,,,,,,introduction to a publication about an investigation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0000944,handedness assay,handedness test,A handedness assay measures the unequal distribution of fine motor skill between the left and right hands typically in human subjects by means of some questionnaire and scoring procedure.,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,handedness test,,,,,,,,,,,,,,,A handedness assay measures the unequal distribution of fine motor skill between the left and right hands typically in human subjects by means of some questionnaire and scoring procedure.,http://en.wikipedia.org/wiki/Handedness,,,,,,handedness assay,,The Edinburgh handedness assay is a specific method of determing handedness,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000944,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,handedness assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0000897,DEPC structure mapping assay,,is a single-nucleotide-resolution nucleic acid structure mapping assay which uses DEPC as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,false,,,http://purl.obolibrary.org/obo/OBI_0001017,,http://purl.obolibrary.org/obo/OBI_0000441,,,,,,,,,,,,,,,,,is a single-nucleotide-resolution nucleic acid structure mapping assay which uses DEPC as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,RNA ontology,,,,,,DEPC structure mapping assay,,PMID:2446263. Probing the structure of RNAs in solution. Nucleic Acids Res. 1987 Nov 25;15(22):9109-28.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000897,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DEPC structure mapping assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_1110196,epitope specific IL-1b release by T cells,,A biological process where T cells produce IL-1b resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/OBI_0001193|http://purl.obolibrary.org/obo/GO_0032611,,,,,,,,,,,,,,,,,,,A biological process where T cells produce IL-1b resulting from the recognition of a T cell epitope.,IEDB,,,,,,epitope specific IL-1b release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110196,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific IL-1b release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/BFO_0000011,spatiotemporal region,,,false,,,http://purl.obolibrary.org/obo/BFO_0000003,,,,,,,SpatiotemporalRegion,st-region,,,,,,,,,,,,,,,,,,spatiotemporal region,A spatiotemporal region is an occurrent entity that is part of spacetime. (axiom label in BFO2 Reference: [095-001]),the spatiotemporal region occupied by a process of cellular meiosis.|the spatiotemporal region occupied by the development of a cancer tumor|the spatiotemporal region occupied by a human life,,,,,,,,(forall (r) (if (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion r r))) // axiom label in BFO2 CLIF: [107-002] |(forall (x t) (if (SpatioTemporalRegion x) (exists (y) (and (SpatialRegion y) (spatiallyProjectsOntoAt x y t))))) // axiom label in BFO2 CLIF: [099-001] |(forall (x y) (if (and (SpatioTemporalRegion x) (occurrentPartOf y x)) (SpatioTemporalRegion y))) // axiom label in BFO2 CLIF: [096-001] |(forall (x) (if (SpatioTemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [095-001] |(forall (x) (if (SpatioTemporalRegion x) (exists (y) (and (TemporalRegion y) (temporallyProjectsOnto x y))))) // axiom label in BFO2 CLIF: [098-001] ,All parts of spatiotemporal regions are spatiotemporal regions. (axiom label in BFO2 Reference: [096-001])|Each spatiotemporal region projects_onto some temporal region. (axiom label in BFO2 Reference: [098-001])|Every spatiotemporal region s is such that s occupies_spatiotemporal_region s. (axiom label in BFO2 Reference: [107-002])|Every spatiotemporal region occupies_spatiotemporal_region itself.|Each spatiotemporal region at any time t projects_onto some spatial region at t. (axiom label in BFO2 Reference: [099-001]),,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000011,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,spatiotemporal region,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000116,worker role,worker,"a personnel role played by a party who executes a component of the study plan; this can occur before, during, after or outside the study timeline",false,,,http://purl.obolibrary.org/obo/OBI_0000202,,,,worker,,,,,,,,,,,,,,,"a personnel role played by a party who executes a component of the study plan; this can occur before, during, after or outside the study timeline",OBI,,,,,"""executes the study plan"" includes the suppliers and manufacturers of reagents and other materials used in the study",worker role,,Public sector workers in states that run their own OSHA programs are covered by those states.   http://www.osha.gov/as/opa/worker/index.html,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000116,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,worker role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Jennifer Fostel,,
http://purl.obolibrary.org/obo/IAO_0000322,institution list,,part of a document that has parts that are institution identifications associated with the authors of the document,false,,,http://purl.obolibrary.org/obo/IAO_0000314,,,,,,,,,,,,,,,,,,,part of a document that has parts that are institution identifications associated with the authors of the document,,,,,,,institution list,,The University of Colorado Denver School of Medicine and the University of Colorado Boulder.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000303,,,,,,,,,,,,,,,,IAO:0000322,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,institution list,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0000750,study design independent variable,independent variable|experimental factor|study factor,"a directive information entity that is part of a study design. Independent variables are entities whose values are selected to determine its relationship to an observed phenomenon (the dependent variable). In such an experiment, an attempt is made to find evidence that the values of the independent variable determine the values of the dependent variable (that which is being measured). The independent variable can be changed as required, and its values do not represent a problem requiring explanation in an analysis, but are taken simply as given. The dependent variable on the other hand, usually cannot be directly controlled",false,,,http://purl.obolibrary.org/obo/IAO_0000033,,,,independent variable|experimental factor,,,,,,,,,,,,,2009-03-16: work has been done on this term during during the OBI workshop winter 2009 and the current definition was considered acceptable for use in OBI. If there is a need to modify thisdefinition please notify OBI.,,"a directive information entity that is part of a study design. Independent variables are entities whose values are selected to determine its relationship to an observed phenomenon (the dependent variable). In such an experiment, an attempt is made to find evidence that the values of the independent variable determine the values of the dependent variable (that which is being measured). The independent variable can be changed as required, and its values do not represent a problem requiring explanation in an analysis, but are taken simply as given. The dependent variable on the other hand, usually cannot be directly controlled",Web: http://en.wikipedia.org/wiki/Dependent_and_independent_variables,,,,,"In the Philly 2013 workshop the label was chosen to distinguish it from ""dependent variable"" as used in statistical modelling. See: http://en.wikipedia.org/wiki/Statistical_modeling|2/2/2009 Original definition - In the design of experiments, independent variables are those whose values are controlled or selected by the person experimenting (experimenter) to determine its relationship to an observed phenomenon (the dependent variable). In such an experiment, an attempt is made to find evidence that the values of the independent variable determine the values of the dependent variable (that which is being measured). The independent variable can be changed as required, and its values do not represent a problem requiring explanation in an analysis, but are taken simply as given. The dependent variable on the other hand, usually cannot be directly controlled.",study design independent variable,,"In a study in which gene expression is measured in patients between 8 month to 4 years old that have mild or severe malaria and in which the hypothesis is that gene expression in that age group is a function of disease status, disease status is the independent variable.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0500000,OBI:0000750,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,study factor,study design independent variable,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Alan Ruttenberg|PERSON: Bjoern Peters|PERSON: Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0200073,family wise error rate correction method,FWER correction,A family wise error rate correction method is a multiple testing procedure that controls the probability of at least one false positive.,false,,,http://purl.obolibrary.org/obo/OBI_0200089,,http://purl.obolibrary.org/obo/OBI_0000791,,FWER correction,,,,,,,,,,,,,,,A family wise error rate correction method is a multiple testing procedure that controls the probability of at least one false positive.,"Dudoit, Sandrine and van der Laan, Mark J. (2008) Multiple Testing Procedures with Applications to Genomics.  New York: Springer , p. 19",,,,,"2011-03-31: [PRS]. 
creating a defined class by specifying the necessary output of dt
allows correct classification of FWER dt",family wise error rate correction method,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200073,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,family wise error rate correction method,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra|Monnie McGee,,
http://purl.obolibrary.org/obo/OBI_0002038,ribosomal profiling by sequencing assay,Ribo-seq assay|ribosomal profiling|Ribo-seq,A RNA-seq assay to sequence only mRNA protected by the ribosome during translation.,false,,,http://purl.obolibrary.org/obo/OBI_0001271,,,,Ribo-seq assay|ribosomal profiling|Ribo-seq,,,,,,,,,,,,,,,A RNA-seq assay to sequence only mRNA protected by the ribosome during translation.,"Ingolia, Nicholas T. (28 January 2014). ""Ribosome profiling: new views of translation, from single codons to genome scale"". Nature Reviews Genetics 15 (3): 205-213. doi:10.1038/nrg3645. PMID 24468696.",,,,,,ribosomal profiling by sequencing assay,,"Aspden et al., (August 2014). ""Extensive translation of small open reading frames revealed by poly-ribo-seq."" eLIFE 2014;3:e03528",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002038,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ribosomal profiling by sequencing assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/UBERON_0001874,putamen,,"Subcortical nucleus of telencephalic , which together with the caudate nucleus, forms the striatum. The putamen lies lateral to the internal capsule and medial to the external medullary lamina, and is separated from the caudate nucleus by the fibers of the internal capsule for most of its length, except at its anterior portion.",false,,,http://purl.obolibrary.org/obo/CARO_0000055,,,,,,,,,,,,,,,,,,,"Subcortical nucleus of telencephalic , which together with the caudate nucleus, forms the striatum. The putamen lies lateral to the internal capsule and medial to the external medullary lamina, and is separated from the caudate nucleus by the fibers of the internal capsule for most of its length, except at its anterior portion.",,,,,,,putamen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UBERON:0001874,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uberon.owl,,,,,,,,,,,,,,,,,,,putamen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/UBERON_0001873,caudate nucleus,,"Subcortical nucleus of telecephalic origin consisting of an elongated gray mass lying lateral to and bordering the lateral ventricle. It is divided into a head, body and tail in some species.",false,,,http://purl.obolibrary.org/obo/CARO_0000055,,,,,,,,,,,,,,,,,,,"Subcortical nucleus of telecephalic origin consisting of an elongated gray mass lying lateral to and bordering the lateral ventricle. It is divided into a head, body and tail in some species.",,,,,,,caudate nucleus,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UBERON:0001873,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uberon.owl,,,,,,,,,,,,,,,,,,,caudate nucleus,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000470,mass spectrometry assay,,An assay that identifies the amount and type of material entities present in a sample by fragmenting it and measuring the mass-to-charge ratio of the resulting particles.,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,An assay that identifies the amount and type of material entities present in a sample by fragmenting it and measuring the mass-to-charge ratio of the resulting particles.,Philippe Rocca-Serra,,,,,,mass spectrometry assay,,"Identification of a proteins cut out from a 2D gel by cleaving it into peptides using trypsin digestion using electrospray ionizatino to ensure the peptides are charged, and accelerating them with an electro magnetic field in which the flight path is determined by the mass / charge ratio of the peptides. Comparing the mass/charge ratio of peptides in the proteins with databases of protein sequences allows to identify which protein gave rise to the peptides.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000470,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,mass spectrometry assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/GO_0042098,T cell proliferation,,The expansion of a T cell population by cell division. Follows T cell activation.,false,,,http://purl.obolibrary.org/obo/GO_0008283,,,,,,,,,,,,,,,,,,,The expansion of a T cell population by cell division. Follows T cell activation.,,,,,,,T cell proliferation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0042098,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,T cell proliferation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001622,investigation title,project title|study title,A textual entity that denotes an investigation.,false,,,http://purl.obolibrary.org/obo/IAO_0000300,,,,,,,,,,,,,,,,,,,A textual entity that denotes an investigation.,NIAID GSCID-BRC metadata working group,http://purl.obolibrary.org/obo/OBI_0000066,,,,,investigation title,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001622,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,study title,investigation title,,,,,,project title,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"Person:Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000923,surface plasmon resonance binding assay,,"A binding assay that uses the detection of electromagnetic waves in a surface to detect material entities adsorbed to the surface, which change the local optical index of refraction.",false,,,http://purl.obolibrary.org/obo/OBI_0001146,,,,,,,,,,,,,,,,,,,"A binding assay that uses the detection of electromagnetic waves in a surface to detect material entities adsorbed to the surface, which change the local optical index of refraction.",IEDB,,,,,,surface plasmon resonance binding assay,,"Running a Biacore instrument to measure the affinity, on and off rates of binding of a plate bound antibody to a antigen passing by in flow.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000923,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,surface plasmon resonance binding assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000578,NMR sample tube,,The sample-tube holds the NMR sample and sits in the nmr probe. It is usually a glass tube of 5-20mm diameter.,false,,,http://purl.obolibrary.org/obo/OBI_0000836,,,,,,,,,,,,,,,,,NMR device,,The sample-tube holds the NMR sample and sits in the nmr probe. It is usually a glass tube of 5-20mm diameter.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400132,,,,,,NMR sample tube,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000566,OBI:0000578,http://purl.obolibrary.org/obo/OBI_0000566,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NMR sample tube,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001639,biological activity assay measuring epitope specific Ig-mediated histamine release,histamine release|biological activity,A B cell epitope specific activation of additional immune response in vitro assay that detects histamine release.,false,,,http://purl.obolibrary.org/obo/OBI_0001704,,,,,,,,,,,,,,,,,,,A B cell epitope specific activation of additional immune response in vitro assay that detects histamine release.,IEDB,,,,,,biological activity assay measuring epitope specific Ig-mediated histamine release,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001639,,,,,,,,,,,,,,,,,,,,,,,,histamine release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific Ig-mediated histamine release,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0600006,killing,death status type|sacrifice|euthanisia|life termination,A protocol application in which an organism is intentionally put to death,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,death status type|sacrifice|euthanisia|life termination,,,,,,,,,,,,,,,A protocol application in which an organism is intentionally put to death,"CEBS, Biomaterial_branch",,,,,"difficult to place this properly - JG. Death process (e.g. unscheduled death) is out of scope but should be added somewhere. All killings have death process as a part, but not all death processes are part of a killing.",killing,,Terminal sacrifice of animals by cervical dislocation at the end of an investigation.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600006,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,killing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0200085,mass spectrometry analysis,,A data transformation which has the objective of spectrum analysis.,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,A data transformation which has the objective of spectrum analysis.,,,,,,,mass spectrometry analysis,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200085,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,mass spectrometry analysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000961,addition of molecular tracer function,,"A reagent application function that is realized when a molecular tracer, such as an antibody or probe is automatically transferred to a biological specimen.",false,,,http://purl.obolibrary.org/obo/OBI_0000960,,,,,,,,,,,,,,,,,,,"A reagent application function that is realized when a molecular tracer, such as an antibody or probe is automatically transferred to a biological specimen.","PERSON: Nicole Vasilevsky, Matthew Brush",,,,,,addition of molecular tracer function,,Immunohistochemical labeling of tissue sections by an autostainer staining system.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000961,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,addition of molecular tracer function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Nicole Vasilevsky, Matthew Brush",,
http://purl.obolibrary.org/obo/IAO_0000096,source code module,,"A source code module is a directive information entity that specifies, using a programming language, some algorithm.",false,,,http://purl.obolibrary.org/obo/IAO_0000033,,,,,,,,,,,,,,,,,,,"A source code module is a directive information entity that specifies, using a programming language, some algorithm.",OBI_0000039|group:OBI,,,,,,source code module,,"The written source code that implements part of an algorithm. Test - if you know that it was written in a specific language, then it can be source code module. We mean here, roughly, the wording of a document such as a perl script.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000096,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,source code module,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Alan Ruttenberg|person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0302890,polymerization,,polymerization is process by which molecular entity of small mass are aggregated in motifs over the course of a chemical reaction catalyzed by enzymes or other molecular entities acting as catalyst. polymerization results in molecular entity of high molecular weight,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,polymerization is process by which molecular entity of small mass are aggregated in motifs over the course of a chemical reaction catalyzed by enzymes or other molecular entities acting as catalyst. polymerization results in molecular entity of high molecular weight,OBI-Branch,,,,,PRS:22102008: need to import catalyst from CHEBI 35223,polymerization,,PMID: 18517209. The electronic role of DNA-functionalized carbon nanotubes: efficacy for in situ polymerization of conducting polymer nanocomposites. J Am Chem Soc. 2008 Jun 25;130(25):7921-8. Epub 2008 Jun 3.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_23367,http://purl.obolibrary.org/obo/CHEBI_33839,,,OBI:0302890,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,polymerization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0200054,global modularity calculation,,A network graph quality calculation in which an input data set of subgraph modules and their in-degree and out-degree qualities is used to calculate the average modularity of subgraphs within the network.,false,,,http://purl.obolibrary.org/obo/OBI_0200147,,,,,,,,,,,,,,,,,,,A network graph quality calculation in which an input data set of subgraph modules and their in-degree and out-degree qualities is used to calculate the average modularity of subgraphs within the network.,PERSON: Richard Scheuermann,,,,,,global modularity calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200054,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,global modularity calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Richard Scheuermann,,
http://purl.obolibrary.org/obo/OBI_0001064,automatic tissue processor,,"A device for processing histological tissue having a tissue carrier basket suspended from a turntable overlying a plurality of beakers suspended from a carrier plate. The turntable is raised, indexed, and lowered by a suitable driving mechanism to move the tissue basket sequentially through the beakers. Timers can each be programmed to control the movement of the turntable to provide various different cycles for processing the tissue. Some of the beakers are received in individual thermal baths to heat and control the temperature of the substances received in the beakers for treating the tissue.",false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,"A device for processing histological tissue having a tissue carrier basket suspended from a turntable overlying a plurality of beakers suspended from a carrier plate. The turntable is raised, indexed, and lowered by a suitable driving mechanism to move the tissue basket sequentially through the beakers. Timers can each be programmed to control the movement of the turntable to provide various different cycles for processing the tissue. Some of the beakers are received in individual thermal baths to heat and control the temperature of the substances received in the beakers for treating the tissue.",United States Patent 3762362,,,,,,automatic tissue processor,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000379|http://purl.obolibrary.org/obo/OBI_0000960,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001064,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,automatic tissue processor,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001379,cytometric bead array assay measuring epitope specific interferon-gamma production by T cells,IFNg release|cytometric bead array,An assay of epitope specific interferon-gamma production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001414,,,,,,,,,,,,,,,,,,,An assay of epitope specific interferon-gamma production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific interferon-gamma production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001379,,,,,,,,,,,,,,,,,,,,,,,,IFNg release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific interferon-gamma production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001650,immunoblot assay measuring binding of a B cell epitope:antibody complex,qualitative binding|western blot,A B cell epitope qualitative binding to antibody assay that uses an immunoblot assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001703,,,,,,,,,,,,,,,,,,,A B cell epitope qualitative binding to antibody assay that uses an immunoblot assay.,IEDB,,,,,,immunoblot assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001650,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|western blot,,,,,,,,,,,,,,,,,,,,,,immunoblot assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000068,reporting party role,submitter|reporting party,a study personnel role played by a party who reports the outcome of a study component,false,,,http://purl.obolibrary.org/obo/OBI_0000202,,,,submitter|reporting party,,,,,,,,,,,,,,,a study personnel role played by a party who reports the outcome of a study component,OBI,,,,,"MO:submitter mapped to this term. So, alternative term 'submitter' was added.",reporting party role,,"The first section has been pre-designated as the 'Reporting Party' section and should be filled with the Reporting Party's personal information.  http://www.mercedsheriff.com/SelfReporting.htm|Person who prepares microarray data in MAGE-TAB format and submits to a database, such as ArrayExpress.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000068,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,reporting party role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0001583,half life of binding datum,,A half life datum of the time it takes for 50% of bound complexes in an ensemble to disassociate in absence of re-association. ,false,,,http://purl.obolibrary.org/obo/OBI_0001144|http://purl.obolibrary.org/obo/OBI_0001171,,,,,,,,,,,,,,,,,,,A half life datum of the time it takes for 50% of bound complexes in an ensemble to disassociate in absence of re-association. ,IEDB,,,,,,half life of binding datum,,The 45 minute period in which one half of the complexes formed by peptide ligand bound to a  HLA-A*0201molecule disassociate.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001583,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,half life of binding datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Bjoern Peters, Randi Vita",,
http://purl.obolibrary.org/obo/OBI_0001598,data maintenance service,,"A maintenance service in which a service provider actively manages or maintains data or a database for the service consumer.  Maintenance of the data is performed to maintain its integrity or enhance its quality or utility for the consumer, but new data is not generated as a result of the maintenance. ",false,,,http://purl.obolibrary.org/obo/OBI_0001530,,,,,,,,,,,,,,,,,,,"A maintenance service in which a service provider actively manages or maintains data or a database for the service consumer.  Maintenance of the data is performed to maintain its integrity or enhance its quality or utility for the consumer, but new data is not generated as a result of the maintenance. ",PERSON: Matthew Brush,,,,,,data maintenance service,,"A database management service, a web hosting service.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001598,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,data maintenance service,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Carlo Torniai|PERSON: Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_0200105,partial least square regression analysis,PLS-RA,"Partial least squares regression is an extension of the multiple linear regression model (see, e.g., Multiple Regression or General Stepwise Regression). In its simplest form, a linear model specifies the (linear) relationship between a dependent (response) variable Y, and a set of predictor variables, the X's, so that
Y = b0 + b1X1 + b2X2 + ... + bpXp
In this equation b0 is the regression coefficient for the intercept and the bi values are the regression coefficients (for variables 1 through p) computed from the data.",false,,,http://purl.obolibrary.org/obo/OBI_0200102,,,,PLS-RA,,,,,,,,,,,,,,,"Partial least squares regression is an extension of the multiple linear regression model (see, e.g., Multiple Regression or General Stepwise Regression). In its simplest form, a linear model specifies the (linear) relationship between a dependent (response) variable Y, and a set of predictor variables, the X's, so that
Y = b0 + b1X1 + b2X2 + ... + bpXp
In this equation b0 is the regression coefficient for the intercept and the bi values are the regression coefficients (for variables 1 through p) computed from the data.","ARTICLE: de Jong, S. (1993). SIMPLS: An alternative approach to partial least squares regression. Chemometrics and Intelligent Laboratory Systems, 18: 251-263.",,,,,,partial least square regression analysis,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200105,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,partial least square regression analysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Tina Hernandez-Boussard,,
http://purl.obolibrary.org/obo/OBI_0001144,binding constant,,A binding datum about the disposition of two or more material entities to form complexes which comes in the form of a scalar and unit that are utilized in equations that model the binding process,false,,,http://purl.obolibrary.org/obo/OBI_0001181,,,,,,,,,,,,,,,,,,,A binding datum about the disposition of two or more material entities to form complexes which comes in the form of a scalar and unit that are utilized in equations that model the binding process,,,,,,"10/6/11 BP: The distinction between binding datum and binding constant is based on the later being part of an equation. That should be captured in the logical definition here, and used to make it to a defined class. ",binding constant,,"The predicted or measured binding affinity of a peptide to a MHC molecule can be captured in the binding constants ""IC50 = 12 nM"" or ""t 1/2 = 30 minutes"". ",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001144,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,binding constant,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Bjoern Peters, Randi Vita, Jason Greenbaum",,
http://purl.obolibrary.org/obo/IAO_0000183,dendrogram,,"A dendrogram is a report graph which is a tree diagram
frequently used to illustrate the arrangement of the clusters produced by a
clustering algorithm.",false,,,http://purl.obolibrary.org/obo/IAO_0000038,,,,,,,,,,,,,,,,,,,"A dendrogram is a report graph which is a tree diagram
frequently used to illustrate the arrangement of the clusters produced by a
clustering algorithm.",WEB: http://en.wikipedia.org/wiki/Dendrogram,,,,,,dendrogram,,"Dendrograms are often used in computational biology to
illustrate the clustering of genes.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000183,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,dendrogram,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:James Malone|PERSON:Chris Stoeckert|PERSON:Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0600054,selection by survival,,the use of environmental conditions to select for the organism or cells that have a certain trait,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,the use of environmental conditions to select for the organism or cells that have a certain trait,OBI branch derived,,,,,,selection by survival,,The insertion of a gene for antibiotic resistance into a cell population and subsequent growth in the presence of the antibiotic to select for those cells which were successfully transfected,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600054,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,selection by survival,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Kevin Clancy,,
http://purl.obolibrary.org/obo/OBI_0002079,specimens collected in one encounter,specimen set,A collection of specimens that is collected from one source (e.g. one organism) during a time period which for the purpose of the study can be considered to be taken at the same sampling time.,false,,,http://purl.obolibrary.org/obo/OBI_0002076,,,,specimen set,,,,,,,,,,,,,,,A collection of specimens that is collected from one source (e.g. one organism) during a time period which for the purpose of the study can be considered to be taken at the same sampling time.,"OBIB, OBI",,,,,Details see tracker: https://sourceforge.net/p/obi/obi-terms/778/,specimens collected in one encounter,,Both blood and urine specimens collected in one clinical visit; liver and brain specimens taken during an autopsy.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002079,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,specimens collected in one encounter,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Biobank,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000506,photoionization detector,PID,"The selective determination of aromatic hydrocarbons or organo-heteroatom species is the job of the photoionization detector (PID). This device uses ultraviolet light as a means of ionizing an analyte exiting from a GC column. The ions produced by this process are collected by electrodes. The current generated is therefore a measure of the analyte concentration. f the amount of ionization is reproducible for a given compound, pressure, and light source then the current collected at the PID's reaction cell electrodes is reproducibly proportional to the amount of that compound entering the cell. The reason why the compounds that are routinely analyzed are either aromatic hydrocarbons or heteroatom containing compounds (like organosulfur or organophosphorus species) is because these species have ionization potentials (IP) that are within reach of commercially available UV lamps. The available lamp energies range from 8.3 to 11.7 ev, that is, lambda max ranging from 150 nm to 106 nm. Although most PIDs have only one lamp, lamps in the PID are exchanged depending on the compound selectivity required in the analysis.",false,,,http://purl.obolibrary.org/obo/OBI_0000637,,,,PID,,,,,,,,,,,,,,,"The selective determination of aromatic hydrocarbons or organo-heteroatom species is the job of the photoionization detector (PID). This device uses ultraviolet light as a means of ionizing an analyte exiting from a GC column. The ions produced by this process are collected by electrodes. The current generated is therefore a measure of the analyte concentration. f the amount of ionization is reproducible for a given compound, pressure, and light source then the current collected at the PID's reaction cell electrodes is reproducibly proportional to the amount of that compound entering the cell. The reason why the compounds that are routinely analyzed are either aromatic hydrocarbons or heteroatom containing compounds (like organosulfur or organophosphorus species) is because these species have ionization potentials (IP) that are within reach of commercially available UV lamps. The available lamp energies range from 8.3 to 11.7 ev, that is, lambda max ranging from 150 nm to 106 nm. Although most PIDs have only one lamp, lamps in the PID are exchanged depending on the compound selectivity required in the analysis.",WEB:<http://www.chemistry.adelaide.edu.au/external/soc-rel/content/pid.htm>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01090,,,,,,photoionization detector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000506,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,photoionization detector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001304,RNAi profiling by array assay,,"An assay in which double stranded RNA is synthesized with a sequence complementary to a gene(s) of interest and introduced into a cell or organism, where it is recognized as exogenous genetic material and activates the RNAi pathway resulting in knockdown of the transcripts and providing a means to study downstream changes in gene expression.",false,,,http://purl.obolibrary.org/obo/OBI_0000443,,http://purl.obolibrary.org/obo/OBI_0000131,,,,,,,,,,,,,,,,,"An assay in which double stranded RNA is synthesized with a sequence complementary to a gene(s) of interest and introduced into a cell or organism, where it is recognized as exogenous genetic material and activates the RNAi pathway resulting in knockdown of the transcripts and providing a means to study downstream changes in gene expression.",EFO_0001030 RNAi profiling by array,,,,,,RNAi profiling by array assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0400148,,,,,,,,,,,,,,,OBI:0001304,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,RNAi profiling by array assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: James Malone,,
http://purl.obolibrary.org/obo/OBI_0000044,physical document,,A physical document is an object serving as a record of information by means of symbolic marks.,false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,,,,,,,,,,,,,,,,A physical document is an object serving as a record of information by means of symbolic marks.,GROUP: OBI,,,,,,physical document,,a book is a physical document,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000044,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,physical document,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001314,epitope specific T cell enhancement of B cell mediated immune response,,A process of T cell enhancement of B cell mediated immune response resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0035399,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of T cell enhancement of B cell mediated immune response resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific T cell enhancement of B cell mediated immune response,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001314,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific T cell enhancement of B cell mediated immune response,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0200161,quantile number of false positives correction method,QNFP,A quantile number of false positives correction method is a MTP that controls for the pth quantile of the distribution of the number of false positives out of the total number of tests performed',false,,,http://purl.obolibrary.org/obo/OBI_0200089,,,,QNFP,,,,,,,,,,,,,,,A quantile number of false positives correction method is a MTP that controls for the pth quantile of the distribution of the number of false positives out of the total number of tests performed',"Dudoit, Sandrine and van der Laan, Mark J. (2008) Multiple Testing Procedures with Applications to Genomics.  New York: Springer , p. 19",,,,,,quantile number of false positives correction method,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200161,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,quantile number of false positives correction method,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Monnie McGee,,
http://purl.obolibrary.org/obo/OBI_0000710,Li-Cor 4300 DNA Analysis System,,is a DNA sequencer which is manufactured by Li-Cor corporation and enable automated chain termination based DNA sequencing,false,,,http://purl.obolibrary.org/obo/OBI_0400103,,,,,,,,,,,,,,,,,,,is a DNA sequencer which is manufactured by Li-Cor corporation and enable automated chain termination based DNA sequencing,OBI and Li-Cor,,,,,,Li-Cor 4300 DNA Analysis System,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000710,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Li-Cor 4300 DNA Analysis System,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001467,in vivo assay measuring T cell epitope specific disease exacerbation,disease exacerbation|in vivo assay,An efficacy of T cell epitope intervention experiment that uses a disease exacerbation in vivo intervention experiment.,false,,,http://purl.obolibrary.org/obo/OBI_0001484,,,,,,,,,,,,,,,,,,,An efficacy of T cell epitope intervention experiment that uses a disease exacerbation in vivo intervention experiment.,IEDB,,,,,,in vivo assay measuring T cell epitope specific disease exacerbation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001467,,,,,,,,,,,,,,,,,,,,,,,,disease exacerbation|in vivo assay,,,,,,,,,,,,,,,,,,,,,,in vivo assay measuring T cell epitope specific disease exacerbation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0200043,average linkage hierarchical clustering,,"An average linkage hierarchical clustering is an agglomerative hierarchical clustering which generates successive clusters based on a distance measure, where the distance between two clusters is calculated as the average distance between objects from the first cluster and objects from the second cluster.",false,,,http://purl.obolibrary.org/obo/OBI_0200154,,,,,,,,,,,,,,,,,,,"An average linkage hierarchical clustering is an agglomerative hierarchical clustering which generates successive clusters based on a distance measure, where the distance between two clusters is calculated as the average distance between objects from the first cluster and objects from the second cluster.",PERSON: Elisabetta Manduchi,,,,,,average linkage hierarchical clustering,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200043,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,average linkage hierarchical clustering,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0001733,calorimetry assay measuring the association constant [KA] of a B cell epitope:antibody complex,association constant KA|calorimetry|1/nM,A B cell epitope equilibrium association constant (KA) determination assay that uses a calorimetric binding assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001719,,,,,,,,,,,,,,,,,,,A B cell epitope equilibrium association constant (KA) determination assay that uses a calorimetric binding assay.,IEDB,,,,,,calorimetry assay measuring the association constant [KA] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001733,,,,,,,,,,,,,,,,,,,,,,,,association constant KA|calorimetry|1/nM,,,,,,,,,,,,,,,,,,,,,,calorimetry assay measuring the association constant [KA] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0400075,MoFlo,,"A MoFlo is a flow_cytometer_sorter manufactured by Dako Cytomation. It features digital electronics, the option to include several lasers (solid state 488 nm, 635 nm, and a 351 nm diode laser), and has the filtering and collection capacity for up to 10 flouresecent parameters. The MoFlo is an instrument that can be used to both analyze quantitatively and collect cells in a flowing medium.",false,,,http://purl.obolibrary.org/obo/OBI_0400099,,,,,,,,,,,,,,,,,,,"A MoFlo is a flow_cytometer_sorter manufactured by Dako Cytomation. It features digital electronics, the option to include several lasers (solid state 488 nm, 635 nm, and a 351 nm diode laser), and has the filtering and collection capacity for up to 10 flouresecent parameters. The MoFlo is an instrument that can be used to both analyze quantitatively and collect cells in a flowing medium.",http://www.dakousa.com/index/prod_search/prod_groups.htm?productareaid=16,,,,,,MoFlo,,MoFlo at TSRI Flow Cytometry Core Facility,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400075,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,MoFlo,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0000269,number of lost events computer,,A measurement datum recording the number of measurement events lost due to overloading of the analysis chip in a flow cytometer instrument. The datum has a qualitative role,false,,,http://purl.obolibrary.org/obo/IAO_0000109,,,,,,,,,,,,,,,,,,,A measurement datum recording the number of measurement events lost due to overloading of the analysis chip in a flow cytometer instrument. The datum has a qualitative role,Submitted by the Flow Cytometry community in DigitalEntity-FlowCytometry-2007-03-30.txt,,,,,,number of lost events computer,,"0, 125, 787 events lost due to computer busy.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000269,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,number of lost events computer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Kevin Clancy,,
http://purl.obolibrary.org/obo/GO_0097389,chemokine (C-C motif) ligand 21 production,,"The appearance of chemokine (C-C motif) ligand 21 (CCL21) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0032602,,,,,,,,,,,,,,,,,,,"The appearance of chemokine (C-C motif) ligand 21 (CCL21) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,chemokine (C-C motif) ligand 21 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0097389,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,chemokine (C-C motif) ligand 21 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0097388,chemokine (C-C motif) ligand 19 production,,"The appearance of chemokine (C-C motif) ligand 19 (CCL19) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0032602,,,,,,,,,,,,,,,,,,,"The appearance of chemokine (C-C motif) ligand 19 (CCL19) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,chemokine (C-C motif) ligand 19 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0097388,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,chemokine (C-C motif) ligand 19 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001882,target material in specimen specification,Target Material,A plan specification which specifies the type of material that will be assayed in an investigation.,false,,,http://purl.obolibrary.org/obo/IAO_0000104,,,,,,,,,,,,,,,,,,,A plan specification which specifies the type of material that will be assayed in an investigation.,NIAID GSCID-BRC metadata working group,,,,,,target material in specimen specification,,"Some examples of target material are Genome, Purified chromosome, Transcriptome, Phenotype, Proteome.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0500000,OBI:0001882,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,target material in specimen specification,,,,,,Target Material,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000253,artificially induced nucleic acid hybridization,,Is a material transformation in which strands of nucleic acids that are (somewhat) complementary form a double-stranded molecule. Has input at least two single stranded molecules of nucleic acid molecules.,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,Is a material transformation in which strands of nucleic acids that are (somewhat) complementary form a double-stranded molecule. Has input at least two single stranded molecules of nucleic acid molecules.,OBI branch derived,,,,,,artificially induced nucleic acid hybridization,,"www.ornl.gov/sci/techresources/Human_Genome/publicat/97pr/09gloss.html, http://www.accessexcellence.org/RC/VL/GG/nucleic.html, http://omrf.ouhsc.edu/~frank/HYBNOTES.html. http://en.wikipedia.org/wiki/Nucleic_acid_hybridization,http://www.pnas.org/cgi/reprint/46/8/1044.pdf",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000253,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,artificially induced nucleic acid hybridization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0001118,multichannel pipette,,A pipetting system that has a plurality of tip fittings and is used for multi-well plate applications.,false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,A pipetting system that has a plurality of tip fittings and is used for multi-well plate applications.,PERSON: Erik Segerdell,,,,,,multichannel pipette,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453|http://purl.obolibrary.org/obo/OBI_0000379,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001118,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,multichannel pipette,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0400041,FACSvantage,,"The FACSvantage is a flow_cytometer_sorter manufactured by Becton Dickinson. It has analog electronics, three lasers (several options are available), and the filters and PMTs to collect 6 fluorescent parameters and side scatter, and a photodiode to collect forward scatter. The FACSvantage can be used to analyse, sort and collect cells.",false,,,http://purl.obolibrary.org/obo/OBI_0400099,,,,,,,,,,,,,,,,,,,"The FACSvantage is a flow_cytometer_sorter manufactured by Becton Dickinson. It has analog electronics, three lasers (several options are available), and the filters and PMTs to collect 6 fluorescent parameters and side scatter, and a photodiode to collect forward scatter. The FACSvantage can be used to analyse, sort and collect cells.",http://www.bdbiosciences.com/features/products/display_product.php?keyID=42,,,,,,FACSvantage,,FACSvantage at TSRI Flow Cytometry Core Facility,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400041,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,FACSvantage,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0001704,biological activity assay measuring epitope specific activation of additional immune response in vitro,secondary in vitro activity|biological activity,A B cell epitope dependent biological activity determination assay that detects secondary in vitro activity.,false,,,http://purl.obolibrary.org/obo/OBI_0001706,,,,,,,,,,,,,,,,,,,A B cell epitope dependent biological activity determination assay that detects secondary in vitro activity.,IEDB,,,,,,biological activity assay measuring epitope specific activation of additional immune response in vitro,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001704,,,,,,,,,,,,,,,,,,,,,,,,secondary in vitro activity|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific activation of additional immune response in vitro,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/IAO_0000326,supplementary material to a document,supplementary material|appendix,part of a document that is segregated from the rest of the document due to its size,false,,,http://purl.obolibrary.org/obo/IAO_0000314,,,,supplementary material|appendix,,,,,,,,,,,,,,,part of a document that is segregated from the rest of the document due to its size,,,,,,,supplementary material to a document,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000326,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,supplementary material to a document,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/PATO_0001338,mixed sex,,A biological sex quality inhering in a population of multiple sexes.,false,,,http://purl.obolibrary.org/obo/BFO_0000019,,,,,,,,,,,,,,,,,,,A biological sex quality inhering in a population of multiple sexes.,,,,,,,mixed sex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001338,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,mixed sex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0001339,biomaterial purity,,A composition quality inhering in an bearer by virtue of the bearer's homogeneity of a biomaterial.,false,,,http://purl.obolibrary.org/obo/PATO_0001237,,,,,,,,,,,,,,,,,,,A composition quality inhering in an bearer by virtue of the bearer's homogeneity of a biomaterial.,,,,,,,biomaterial purity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001339,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,biomaterial purity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000438,DNA sequence variation detection,,"DNA sequence variation detection is a process which aims at finding changes (expansion, amplification, deletion, mutation) in sequence of DNA molecule.",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,http://purl.obolibrary.org/obo/OBI_0000113|http://purl.obolibrary.org/obo/OBI_0000441,,,,,,,,,,,,,,,,,"DNA sequence variation detection is a process which aims at finding changes (expansion, amplification, deletion, mutation) in sequence of DNA molecule.",OBI Biomaterial,,,,,,DNA sequence variation detection,,Capturing genomic signatures of DNA sequence variation using a standard anonymous microarray platform. Nucleic Acids Res. 2006;34(18):e121. PMID: 17000641,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_16991,http://purl.obolibrary.org/obo/IAO_0000109,,,OBI:0000438,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNA sequence variation detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001612,epitope specific vascular endothelial growth factor production by T cells,,A process of vascular endothelial growth factor production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0010573|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,Date: 2011-11-10; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mappings: assay_mappings.owl,,A process of vascular endothelial growth factor production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific vascular endothelial growth factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001612,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific vascular endothelial growth factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0100067,bronchial alveolar lavage,BAL,"Group of biomaterials present in the bronchial aveolar space of an organism which are collected through lavage including the reagents used to for the lavage process, organisms, cells, and cellular secretions present in the bronchial aveolar space.",false,,,http://purl.obolibrary.org/obo/OBI_0100051,,,,BAL,,,,,,,,,,,,,,,"Group of biomaterials present in the bronchial aveolar space of an organism which are collected through lavage including the reagents used to for the lavage process, organisms, cells, and cellular secretions present in the bronchial aveolar space.",GROUP: IEDB,,,,,,bronchial alveolar lavage,,"solution containing lung derived T cells, eosinophils, and TNFa.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000112,,,,,,,,,,,,OBI:0100067,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,bronchial alveolar lavage,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001877,random access memory,RAM,"Random-access memory (RAM) is a form of computer data storage. A random-access device allows stored data to be accessed directly in any random order. In contrast, other data storage media such as hard disks, CDs, DVDs and magnetic tape, as well as early primary memory types such as drum memory, read and write data only in a predetermined order, consecutively, because of mechanical design limitations. Therefore, the time to access a given data location varies significantly depending on its physical location",false,,,http://purl.obolibrary.org/obo/IAO_0000178,,,,RAM,,,,,,,,,,,,,,,"Random-access memory (RAM) is a form of computer data storage. A random-access device allows stored data to be accessed directly in any random order. In contrast, other data storage media such as hard disks, CDs, DVDs and magnetic tape, as well as early primary memory types such as drum memory, read and write data only in a predetermined order, consecutively, because of mechanical design limitations. Therefore, the time to access a given data location varies significantly depending on its physical location","http://en.wikipedia.org/wiki/RAM
last accessed: 2013-12-02",,,,,,random access memory,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001877,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,random access memory,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Alejandra Gonzalez-Beltran|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001444,genotyping design,,"A study design that classifies an individual or group of individuals on the basis of alleles, haplotypes, SNPs.",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A study design that classifies an individual or group of individuals on the basis of alleles, haplotypes, SNPs.",MO_560 genotyping_design,,,,,,genotyping design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000113,,,,,,,,,,,,,,,,OBI:0001444,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,genotyping design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0400135,image cytometer,,An image_cytometer is an instrument for image-based study or measurement of cells.,false,,,http://purl.obolibrary.org/obo/OBI_0000398,,,,,,,,,,,,,,,,,,,An image_cytometer is an instrument for image-based study or measurement of cells.,http://web.mit.edu/solab/Research/ImageCytometry.html,,,,,,image cytometer,,"The most common current application of image cytometry is for DNA analysis, followed by quantitation of immunohistochemical staining.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/OBI_0000397,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0400079|http://purl.obolibrary.org/obo/OBI_0400065|http://purl.obolibrary.org/obo/OBI_0400082,,,,,,,,,,,,,,,,OBI:0400135,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,image cytometer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0000987,obsolete_general scalar measurement datum,,,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,,,,,,,"4/10/2011 BP: It is unclear to me why we need this, and don't just use the scalar measurement datum. |See tracker:
https://sourceforge.net/tracker/index.php?func=detail&aid=3302925&group_id=177891&atid=886178",obsolete_general scalar measurement datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000124,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,OBI:0000987,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_general scalar measurement datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001406,biological activity assay measuring epitope specific interleukin-3 production by T cells,IL-3 release|biological activity,A T cell epitope specific cytokine production assay that detects interleukin-3 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects interleukin-3 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific interleukin-3 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001406,,,,,,,,,,,,,,,,,,,,,,,,IL-3 release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific interleukin-3 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001277,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-2 production by T cells,IL-2 release|RNA/DNA detection,An assay of epitope specific interleukin-2 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001445,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-2 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-2 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001277,,,,,,,,,,,,,,,,,,,,,,,,IL-2 release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-2 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/GO_0032641,lymphotoxin A production,TNF beta production,"The appearance of lymphotoxin A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0071706,,,,TNF beta production,,,,,,,,,,,,,,,"The appearance of lymphotoxin A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,lymphotoxin A production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032641,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,lymphotoxin A production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032640,tumor necrosis factor production,TNF alpha production,"The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0071706,,,,TNF alpha production,,,,,,,,,,,,,,,"The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,tumor necrosis factor production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032640,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,tumor necrosis factor production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0400114,sonicator,,"A device that converts a variable electrical current to mechanical vibration of a metallic probe. The device is used for the lysis of cells, the mixing of compounds or solutions, to framgent molecules of DNA, or to create emulsions.",false,,,http://purl.obolibrary.org/obo/OBI_0001033,,,,,,,,,,,,,,,,,,,"A device that converts a variable electrical current to mechanical vibration of a metallic probe. The device is used for the lysis of cells, the mixing of compounds or solutions, to framgent molecules of DNA, or to create emulsions.",MO,,,,,,sonicator,,Sonicator 3000,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/OBI_0000377,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400114,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sonicator,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Trish Whetzel,,
http://purl.obolibrary.org/obo/OBI_0001889,specimen provider principal investigator,Sample Provider Principal Investigator (PI) Name,A person who is a principal investigator and provides the specimen,false,,,http://purl.obolibrary.org/obo/NCBITaxon_9606,,,,,,,,,,,,,,,,,,,A person who is a principal investigator and provides the specimen,NIAID GSCID-BRC metadata working group,,,,,,specimen provider principal investigator,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001889,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,specimen provider principal investigator,,,,,,Sample Provider Principal Investigator (PI) Name,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_1110170,ELISPOT assay measuring epitope specific interleukin-10 production by T cells,IL-10 release|ELISPOT,An assay of epitope specific interleukin-10 production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001209,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-10 production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific interleukin-10 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110170,,,,,,,,,,,,,,,,,,,,,,,,IL-10 release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific interleukin-10 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000740,material sample role,,A material sample role is a specimen role borne by a material entity that is the output of a material sampling process.,false,,,http://purl.obolibrary.org/obo/OBI_0000112,,,,,,,,,,,,,,,,,,,A material sample role is a specimen role borne by a material entity that is the output of a material sampling process.,,,,,,7/13/09: Note that this is a relational role: between the sample taken and the 'sampled' material of which the sample is thought to be representative off.,material sample role,,a role borne by a portion of blood taken to represent all the blood in an organism; the role borne by a population of humans with HIV enrolled in a study taken to represent patients with HIV in general.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000740,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,material sample role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0040029,"regulation of gene expression, epigenetic",,"Any process that modulates the frequency, rate or extent of gene expression; the process is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence.",false,,,http://purl.obolibrary.org/obo/GO_0040030,,,,,,,,,,,,,,,,,,,"Any process that modulates the frequency, rate or extent of gene expression; the process is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence.",,,,,,,"regulation of gene expression, epigenetic",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0040029,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,"regulation of gene expression, epigenetic",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001246,ELISA measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells,TNF release|ELISA,An assay of epitope specific tumor necrosis factor superfamily cytokine production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001400,,,,,,,,,,,,,,,,,,,An assay of epitope specific tumor necrosis factor superfamily cytokine production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001246,,,,,,,,,,,,,,,,,,,,,,,,TNF release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001519,cell lysate MHC direct binding assay of a MHC:ligand complex using fluorescence detection,qualitative binding|lysate MHC/direct/fluorescence,A cell lysate MHC binding assay that uses fluorescence detection to detect direct binding.,false,,,http://purl.obolibrary.org/obo/OBI_0001499|http://purl.obolibrary.org/obo/OBI_0001579,,,,,,,,,,,,,,,,,,,A cell lysate MHC binding assay that uses fluorescence detection to detect direct binding.,IEDB,,,,,,cell lysate MHC direct binding assay of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001501,,,,,,,,,,,,,,,,OBI:0001519,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|lysate MHC/direct/fluorescence,,,,,,,,,,,,,,,,,,,,,,cell lysate MHC direct binding assay of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_1110054,autoimmune disease,,Is a disease characterized by an immune response of an organism against parts of itself,false,,,http://purl.obolibrary.org/obo/OGMS_0000031,,,,,,,,,,,,,,,,,,,Is a disease characterized by an immune response of an organism against parts of itself,IEDB,,,,,,autoimmune disease,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110054,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,autoimmune disease,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/UBERON_0000105,life cycle stage,,A spatiotemporal region encompassing some part of the life cycle of an organism.,false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,A spatiotemporal region encompassing some part of the life cycle of an organism.,,,,,,,life cycle stage,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UBERON:0000105,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uberon.owl,,,,,,,,,,,,,,,,,,,life cycle stage,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_1110038,RMA cell line,,"A cell line derived from a mouse lymphoma, specifically a Rauscher virus-induced tumor.This cell ine is antigen processing-defective and expresses a very low level of MHC molecules on its surface.",false,,,http://purl.obolibrary.org/obo/CLO_0009828,,,,,,,,,,,,,,,,,,,"A cell line derived from a mouse lymphoma, specifically a Rauscher virus-induced tumor.This cell ine is antigen processing-defective and expresses a very low level of MHC molecules on its surface.",IEDB,,,,,,RMA cell line,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110038,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,RMA cell line,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001836,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-16 production by T cells,IL-16 release|RNA/DNA detection,An assay of epitope specific interleukin-16 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001280,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-16 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-16 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001836,,,,,,,,,,,,,,,,,,,,,,,,IL-16 release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-16 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000366,metabolite profiling,metabolite assay,metabolite profiling is a process which aims at detecting and identifying chemical entities resulting from biochemical and cellular metabolism,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,http://purl.obolibrary.org/obo/OBI_0000441,,metabolite assay,,,,,,,,,,,,,,,metabolite profiling is a process which aims at detecting and identifying chemical entities resulting from biochemical and cellular metabolism,OBI,,,,,,metabolite profiling,,Metabolite profiling of human colon carcinoma - deregulation of TCA cycle and amino acid turnover. Mol Cancer. 2008 Sep 18;7(1):72. PMID: 18799019,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100051,http://purl.obolibrary.org/obo/IAO_0000109,,,OBI:0000366,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,metabolite profiling,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001400,biological activity assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells,TNF release|biological activity,A T cell epitope specific cytokine production assay that detects tumor necrosis factor superfamily cytokine production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects tumor necrosis factor superfamily cytokine production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001400,,,,,,,,,,,,,,,,,,,,,,,,TNF release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0002023,Human Genome U133 Plus 2.0 tiling array,Affymetrix HT Human Genome U133 Plus 2 Array Plate Set|HG-U133 Plus 2|HG-U133 Plus 2 array,"A tiling array which is  a comprehensive whole human genome expression array manufactured by the Affymetrix corporation. Built to analyze DNA sequence copy number by comparative genomic hybridization for human DNA against 47,000 transcripts and variants.",false,,,http://purl.obolibrary.org/obo/OBI_0001307,,,,Affymetrix HT Human Genome U133 Plus 2 Array Plate Set|HG-U133 Plus 2|HG-U133 Plus 2 array,,,,,,,,,,,,,,,"A tiling array which is  a comprehensive whole human genome expression array manufactured by the Affymetrix corporation. Built to analyze DNA sequence copy number by comparative genomic hybridization for human DNA against 47,000 transcripts and variants.",http://www.affymetrix.com/estore/esearch/search.jsp?pd=131455&N=4294967292,,,,,,Human Genome U133 Plus 2.0 tiling array,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002023,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Human Genome U133 Plus 2.0 tiling array,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001854,protein and RNA interaction identification objective,,A sequence feature identification objective that aims to characterize the interactions between protein and RNA.,false,,,http://purl.obolibrary.org/obo/OBI_0000113,,,,,,,,,,,,,,,,,,,A sequence feature identification objective that aims to characterize the interactions between protein and RNA.,Jie Zheng,,,,,JZ: Term added for ENCODE project requested assays. Definition adapted from 'protein and DNA interaction identification objective'.,protein and RNA interaction identification objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001854,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,protein and RNA interaction identification objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jie Zheng,,
http://purl.obolibrary.org/obo/OBI_0001245,detection of specific nucleic acids with complementary probes assay measuring epitope specific perforin release,perforin release|RNA/DNA detection,A T cell epitope specific perforin release assay that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001497,,,,,,,,,,,,,,,,,,,A T cell epitope specific perforin release assay that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific perforin release,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001245,,,,,,,,,,,,,,,,,,,,,,,,perforin release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific perforin release,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_1110109,target of material addition,,A material entity into which another is being added in a material combinatino process,false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,A material entity into which another is being added in a material combinatino process,IEDB,,,,,10/26/09: This defined class is used as a 'macro' to reduce the size of the IEDB export.,target of material addition,,A cell culture into which a mixture of peptides is being added.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110109,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,target of material addition,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0001025,pressure,,A physical quality that inheres in a bearer by virtue of the bearer's amount of force per unit area it exerts.,false,,,http://purl.obolibrary.org/obo/PATO_0001237,,,,,,,,,,,,,,,,,,,A physical quality that inheres in a bearer by virtue of the bearer's amount of force per unit area it exerts.,,,,,,,pressure,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001025,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,pressure,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0400169,microscope,,"A microscope is an instrument which magnifies the view on objects (too small to be viewed by the naked eye) under increased resolution. A microscope can be an optical instrument but also and electronic instrument. There are various kind of optical microscopes, e.g confocal microscope, epifluoresence microscope)",false,,,http://purl.obolibrary.org/obo/OBI_0000398,,,,,,,,,,,,,,,,,,,"A microscope is an instrument which magnifies the view on objects (too small to be viewed by the naked eye) under increased resolution. A microscope can be an optical instrument but also and electronic instrument. There are various kind of optical microscopes, e.g confocal microscope, epifluoresence microscope)",wikipedia,,,,,,microscope,,PMID:18466942. A light and transmission electron microscope study of hepatic portal tracts in the rhesus monkey (Macacus rhesus). Tissue Cell. 2008 May 6,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000397|http://purl.obolibrary.org/obo/OBI_0000369,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400169,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,microscope,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Phillippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000196,role of impartial witness,impartial witness,a role which inheres in a Homo sapiens and is realized during a clinical trial - the impartial witness is independent of the trial and cannot be unfairly influenced by people involved with the trial,false,,,http://purl.obolibrary.org/obo/OBI_0000016,,,,impartial witness,,,,,,,,,,,,,,,a role which inheres in a Homo sapiens and is realized during a clinical trial - the impartial witness is independent of the trial and cannot be unfairly influenced by people involved with the trial,,,,,,"impartial witness. A person, who is independent of the trial, who cannot be unfairly influenced by people involved with the trial, who attends the informed consent process if the subject or the subject's legally acceptable representative cannot read, and who",role of impartial witness,,"According to GCP , an impartial witness should be present for an
illiterate subject. PharmPK Discussion, http://www.boomer.org/pkin/PK06/PK2006253.html",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000196,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,role of impartial witness,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jennifer Fostel|Person: Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0001294,wild type organism genotype information,,a genotype information about an organism and includes information that there are no known modifications to the genetic background. Generally it is the genotype information of a representative individual from a class of organisms.,false,,,http://purl.obolibrary.org/obo/OBI_0001305,,,,,,,,,,,,,,,,,,,a genotype information about an organism and includes information that there are no known modifications to the genetic background. Generally it is the genotype information of a representative individual from a class of organisms.,Group: OBI group,,,,,"proposed and discussed on San Diego OBI workshop, March 2011",wild type organism genotype information,,C57BL/6J wild type,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001294,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,wild type organism genotype information,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Group: OBI group,,
http://purl.obolibrary.org/obo/OBI_0000669,tritiated thymidine incorporation assay,,A cell proliferation assay in which cells are cultured in the presence of tritiated thymidine which is incorporated into newly synthesized DNA of replicating cells (during the S phase of the cell cycle). The radioactivity of tritiated thymidine in a cell is a proxy for cells that were actively replicating.,false,,,http://purl.obolibrary.org/obo/OBI_0000891,,,,,,,,,,,,,,,,,,,A cell proliferation assay in which cells are cultured in the presence of tritiated thymidine which is incorporated into newly synthesized DNA of replicating cells (during the S phase of the cell cycle). The radioactivity of tritiated thymidine in a cell is a proxy for cells that were actively replicating.,IEDB,,,,,,tritiated thymidine incorporation assay,,"The measurement of T cell proliferation as a response to a viral peptide by culturing T cells stimulated with APCs and peptide in the presence of tritiated thymidine, and using a scintillation counter to detect the radioactivity.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000201,,,,,,,,,,,,,,,,OBI:0000669,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,tritiated thymidine incorporation assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001765,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells,CCL4/MIP-1b release|RNA/DNA detection,An assay of epitope specific chemokine (C-C motif) ligand 4 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001345,,,,,,,,,,,,,,,,,,,An assay of epitope specific chemokine (C-C motif) ligand 4 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001765,,,,,,,,,,,,,,,,,,,,,,,,CCL4/MIP-1b release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0200190,clustered data visualization,,A data visualization which has input of a clustered data set and produces an output of a report graph which is capable of rendering data of this type.,false,,,http://purl.obolibrary.org/obo/OBI_0200111,,,,,,,,,,,,,,,,,,,A data visualization which has input of a clustered data set and produces an output of a report graph which is capable of rendering data of this type.,,,,,,,clustered data visualization,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200190,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,clustered data visualization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/IAO_0000131,serial number,,"A serial number is an information content entity which is a unique sequence of characters borne by part of manufactured product or its packaging that is assigned to each individual in some class of products, and so can serve as a way to identify an individual product within the class. Serial numbers can be encoded in a variety of other information objects, such as bar codes, numerals, or patterns of dots.",false,,,http://purl.obolibrary.org/obo/IAO_0000028,,,,,,,,,,,,,,,,,,,"A serial number is an information content entity which is a unique sequence of characters borne by part of manufactured product or its packaging that is assigned to each individual in some class of products, and so can serve as a way to identify an individual product within the class. Serial numbers can be encoded in a variety of other information objects, such as bar codes, numerals, or patterns of dots.",,,,,,Note: during the call there was some confusion between serial number and model number. We agreed that it would be very helpful for all those terms to have example of usages - please add if you have any :-),serial number,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000131,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,serial number,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP: IAO,,
http://purl.obolibrary.org/obo/OBI_0001908,testable hypothesis,hypothesis,An information content entity that expresses an assertion that is intended to be tested.,false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,hypothesis,,,,,,,,,,,,,,,An information content entity that expresses an assertion that is intended to be tested.,Group:2013 Philly Workshop group,,,,,"In the Philly 2013 workshop, we recognized the limitations of ""hypothesis textual entity"", and we introduced this as more general. The need for the 'textual entity' term going forward is up for future debate. 
",testable hypothesis,,"that fucoidan has a small statistically significant effect on AT3 level but no useful clinical effect as in-vivo anticoagulant, a paraphrase of part of the last paragraph of the discussion section of the paper 'Pilot clinical study to evaluate the anticoagulant activity of fucoidan', by Lowenthal et. al.PMID:19696660",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001908,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,testable hypothesis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Group:2013 Philly Workshop group,,
http://purl.obolibrary.org/obo/OBI_0200072,curve fitting data transformation,,A curve fitting is a data transformation that has objective curve fitting and that consists of finding a curve which matches a series of data points and possibly other constraints.,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,A curve fitting is a data transformation that has objective curve fitting and that consists of finding a curve which matches a series of data points and possibly other constraints.,WEB: http://en.wikipedia.org/wiki/Curve_fitting,,,,,,curve fitting data transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200072,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,curve fitting data transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Melanie Courtot|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/NCBITaxon_3702,Arabidopsis thaliana,thale cress|thale-cress|mouse-ear cress,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_2759,,,,thale cress|thale-cress|mouse-ear cress,,,,,,,,,,,,,,,,,,,,,,Arabidopsis thaliana,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:3702,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Arabidopsis thaliana,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000930,calorimeter,calorimetry instrument?,A measurement device that is used to calculate the heat flow of a chemical reaction or physical change.,false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,calorimetry instrument?,,,,,,,,,,,,,,,A measurement device that is used to calculate the heat flow of a chemical reaction or physical change.,http://chemistry.about.com/od/chemistryglossary/a/calorimeterdef.htm,,,,,,calorimeter,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000930,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,calorimeter,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Bjoern Peters,,
http://purl.obolibrary.org/obo/VO_0000001,vaccine,,"A vaccine is a processed material with the function that when administered, it prevents or ameliorates a disorder in a target organism by inducing or modifying adaptive immune responses specific to the antigens in the vaccine.",false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,"A vaccine is a processed material with the function that when administered, it prevents or ameliorates a disorder in a target organism by inducing or modifying adaptive immune responses specific to the antigens in the vaccine.",,,,,,,vaccine,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,VO:0000001,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/vo.owl,,,,,,,,,,,,,,,,,,,vaccine,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/VO_0000002,vaccination,,"a process of administering substance in vivo that involves in adding a vaccine into a host (e.g., human) in vivo with the intent to invoke a protective or therapeutic adaptive immune response.",false,,,http://purl.obolibrary.org/obo/OBI_0600007,,,,,,,,,,,,,,,,,,,"a process of administering substance in vivo that involves in adding a vaccine into a host (e.g., human) in vivo with the intent to invoke a protective or therapeutic adaptive immune response.",,,,,,,vaccination,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,VO:0000002,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/vo.owl,,,,,,,,,,,,,,,,,,,vaccination,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200022,variance stabilizing transformation,variance stabilising transformation,"A variance stabilizing transformation is a data transformation, described in PMID 12169536, whose input is a matrix [y_ik] and whose output is a matrix obtained by applying formula (6) in this paper. One of the goals is to obtain an output matrix whose rows have equal variances. The method relies on various assumptions described in the paper.",false,,,http://purl.obolibrary.org/obo/OBI_0200169,,http://purl.obolibrary.org/obo/OBI_0200167,,variance stabilising transformation,,,,,,,,,,,,,,,"A variance stabilizing transformation is a data transformation, described in PMID 12169536, whose input is a matrix [y_ik] and whose output is a matrix obtained by applying formula (6) in this paper. One of the goals is to obtain an output matrix whose rows have equal variances. The method relies on various assumptions described in the paper.",PMID: 12169536,,,,,,variance stabilizing transformation,,"This can be used for expression microarray assay normalization and it is referred to as ""variance stabilizing normalization"", according to the procedure described e.g. in PMID 12169536.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200022,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,variance stabilizing transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Melanie Courtot|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0000519,flow probe,,"An NMR probe that allows the automatized flow-through of a sample. The sample is aspirated via a syringe pump into the Flow probe, the NMR spectrum is acquired and when the experiment is complete, the sample is returned to back to an external source (well plate) or flushed to waste. Sometimes pulsed field gradients (PFG) can be established in flow probes.",false,,,http://purl.obolibrary.org/obo/OBI_0000516,,,,,,,,,,,,,,,,,NMR device,,"An NMR probe that allows the automatized flow-through of a sample. The sample is aspirated via a syringe pump into the Flow probe, the NMR spectrum is acquired and when the experiment is complete, the sample is returned to back to an external source (well plate) or flushed to waste. Sometimes pulsed field gradients (PFG) can be established in flow probes.",WEB:<http://www.varianinc.com/cgi-bin/nav?products/NMR/accessory/auto_samplers/vast/index&cid=HFIH>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400131,,,,,,flow probe,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000519,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,flow probe,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001971,Ion 316 Chip v2,Ion PGM 316 Chip v2|Ion PGM 316 Chip|Ion 316 Chip,"An ion semiconductor chip manufactured by Life Technologies which detects polymerase-driven base incorporation to translate into digital form. The 316 chip is compatible with the Ion Torrent PGM and has a run time of:

3.0 hours for 200 bp reads with an output of 30-50 Mb,
4.9 hours for 400 bp reads with an output of 60 Mb-1 Gb.",false,,,http://purl.obolibrary.org/obo/OBI_0001973,,,,Ion PGM 316 Chip v2|Ion PGM 316 Chip|Ion 316 Chip,,,,,,,,,,,,,,,"An ion semiconductor chip manufactured by Life Technologies which detects polymerase-driven base incorporation to translate into digital form. The 316 chip is compatible with the Ion Torrent PGM and has a run time of:

3.0 hours for 200 bp reads with an output of 30-50 Mb,
4.9 hours for 400 bp reads with an output of 60 Mb-1 Gb.",http://www.lifetechnologies.com/us/en/home/life-science/sequencing/next-generation-sequencing/ion-torrent-next-generation-sequencing-workflow/ion-torrent-next-generation-sequencing-run-sequence/ion-pgm-ion-proton-system-chips.html,,,,,"Issue Tracker #774
https://sourceforge.net/p/obi/obi-terms/774/",Ion 316 Chip v2,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001971,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Ion 316 Chip v2,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Sagar Jain,,
http://purl.obolibrary.org/obo/OBI_0000399,solid support function,,A solid support function is a function of a device on which an entity is kept in a defined position and prevented in its movement,false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,A solid support function is a function of a device on which an entity is kept in a defined position and prevented in its movement,,,,,,,solid support function,,"Taped, glued, pinned, dried or molecularly bonded to a solid support",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000399,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,solid support function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Daniel Schober|Frank Gibson|Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0001871,LSRFortessa X-20,,"A flow cytometer analyzer manifactured by Becton ans Dickinson. Can be configured with up to 5 lasers, 488nm, 532 or 561 nm, 640 nm, 405 nm, 355 nm for measuring up to 20 parameters simultaneously. ",false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,,,,,,,,,,,,,,,,"A flow cytometer analyzer manifactured by Becton ans Dickinson. Can be configured with up to 5 lasers, 488nm, 532 or 561 nm, 640 nm, 405 nm, 355 nm for measuring up to 20 parameters simultaneously. ",http://www.bdbiosciences.com/instruments/lsrx20/index.jsp?WT.srch=1&gclid=CJjJ8JTR5LoCFXBo7AodZycAbg,,,,,,LSRFortessa X-20,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001871,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,LSRFortessa X-20,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Anna Maria Masci,,
http://purl.obolibrary.org/obo/OBI_0400171,animal cage,laboratory cage,a processed material which has the function to define a bounded habitat which is amenable to keeping animals.,false,,,http://purl.obolibrary.org/obo/OBI_0000967,,,,laboratory cage,,,,,,,,,,,,,,,a processed material which has the function to define a bounded habitat which is amenable to keeping animals.,OBI biomaterial branch,,,,,,animal cage,,PMID: 18246864.Barthold SW.Effects of cage density on behavior in young adult mice.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/OBI_0000370,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400171,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,animal cage,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Phillippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000387,cool function,,A cool function is a function to decrease the internal kinetic energy of a material below the initial kinetic energy of that type of material.,false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,A cool function is a function to decrease the internal kinetic energy of a material below the initial kinetic energy of that type of material.,,,,,,,cool function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000387,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cool function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Daniel Schober|Frank Gibson|Melanie Courtot,,
http://purl.obolibrary.org/obo/NCBITaxon_32523,Tetrapoda,tetrapods,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_117571,,,,tetrapods,,,,,,,,,,,,,,,,,,,,,,Tetrapoda,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:32523,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Tetrapoda,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_1110158,ELISA measuring epitope specific interleukin-6 production by T cells,IL-6 release|ELISA,An assay of epitope specific interleukin-6 production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001451,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-6 production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific interleukin-6 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110158,,,,,,,,,,,,,,,,,,,,,,,,IL-6 release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific interleukin-6 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/GO_0001788,antibody-dependent cellular cytotoxicity,,"Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells.",false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,"Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells.",,,,,,,antibody-dependent cellular cytotoxicity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0001788,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,antibody-dependent cellular cytotoxicity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001423,intracellular material detection measuring epitope specific granzyme B release by T cells,granzyme B release|intracellular staining,A T cell epitope specific granzyme B release assay that uses an intracellular material detection by flow cytometry assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001436,,,,,,,,,,,,,,,,,,,A T cell epitope specific granzyme B release assay that uses an intracellular material detection by flow cytometry assay.,IEDB,,,,,,intracellular material detection measuring epitope specific granzyme B release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001423,,,,,,,,,,,,,,,,,,,,,,,,granzyme B release|intracellular staining,,,,,,,,,,,,,,,,,,,,,,intracellular material detection measuring epitope specific granzyme B release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001676,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-7 production by T cells,IL-7 release|RNA/DNA detection,An assay of epitope specific interleukin-7 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001587,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-7 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-7 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001676,,,,,,,,,,,,,,,,,,,,,,,,IL-7 release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-7 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000685,creating a mixture of molecules in solution,,is a process with the objective to prepare a liquid solution of one or more chemicals at desired concentrations.,false,,,http://purl.obolibrary.org/obo/OBI_0000652,,http://purl.obolibrary.org/obo/OBI_0000686|http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,is a process with the objective to prepare a liquid solution of one or more chemicals at desired concentrations.,PERSON: Helen Parkinson,,,,,,creating a mixture of molecules in solution,,The production of PBS,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000040,http://purl.obolibrary.org/obo/OBI_0302729,,,OBI:0000685,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,creating a mixture of molecules in solution,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0400107,computer,,"A computer is an instrument which manipulates (stores, retrieves, and processes) data according to a list of instructions.",false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,"A computer is an instrument which manipulates (stores, retrieves, and processes) data according to a list of instructions.",http://en.wikipedia.org/wiki/Computer,,,,,,computer,,"Apple PowerBook, Dell OptiPlex",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/OBI_0000392,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400107,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,computer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Melanie Courtot|Trish Whetzel,,
http://purl.obolibrary.org/obo/OBI_0200079,mean calculation,,A mean calculation is a descriptive statistics calculation in which the mean is calculated by taking the sum of all of the observations in a data set divided by the total number of observations. It gives a measure of the 'center of gravity' for the data set. It is also known as the first moment.,false,,,http://purl.obolibrary.org/obo/OBI_0200184|http://purl.obolibrary.org/obo/OBI_0200181|http://purl.obolibrary.org/obo/OBI_0200170,,http://purl.obolibrary.org/obo/OBI_0200078,,,,,,,,,,,,,,,From Monnie's file comments - need to add moment_calculation and center_calculation roles but they don't exist yet - (editor note added by James Jan 2008),,A mean calculation is a descriptive statistics calculation in which the mean is calculated by taking the sum of all of the observations in a data set divided by the total number of observations. It gives a measure of the 'center of gravity' for the data set. It is also known as the first moment.,PERSON: James Malone|PERSON: Monnie McGee,,,,,,mean calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200079,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,mean calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Monnie McGee|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/CHEBI_23367,molecular entity,,"Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity.",false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,"Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity.",,,,,,"We are assuming that every molecular entity has to be completely connected by chemical bonds. This excludes protein complexes, which are comprised of minimally two separate molecular entities. We will follow up with Chebi to ensure this is their understanding as well",molecular entity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:23367,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,molecular entity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001920,DNA replication timing by sequencing assay,Repli-seq assay|Repli-seq,An assay in which timing of DNA replication is quantified as a function of genome position based on genome-wide sequencing.,false,,,http://purl.obolibrary.org/obo/OBI_0600047,,http://purl.obolibrary.org/obo/OBI_0001916,,Repli-seq assay|Repli-seq,,,,,,,,,,,,,,,An assay in which timing of DNA replication is quantified as a function of genome position based on genome-wide sequencing.,Hansen et al. Sequencing newly replicated DNA reveals widespread plasticity in human replication timing. Proc Natl Acad Sci U S A. 2010 January 5; 107(1): 139–144. [PMID:19966280],,,,,,DNA replication timing by sequencing assay,,Hansen et al. Sequencing newly replicated DNA reveals widespread plasticity in human replication timing. Proc Natl Acad Sci U S A. 2010 January 5; 107(1): 139–144. [PMID:19966280],,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000690|http://purl.obolibrary.org/obo/OBI_0000626,http://purl.obolibrary.org/obo/OBI_0400103|http://purl.obolibrary.org/obo/OBI_0400099,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_472552,http://purl.obolibrary.org/obo/OBI_0001573,,,OBI:0001920,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNA replication timing by sequencing assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001015,DMS structure mapping assay,single nucleotide resolution mapping assay using DMS probe,a single-nucleotide-resolution nucleic acid structure mapping assay which uses DMS as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,false,,,http://purl.obolibrary.org/obo/OBI_0001017,,http://purl.obolibrary.org/obo/OBI_0000441,,single nucleotide resolution mapping assay using DMS probe,,,,,,,,,,,,,,,a single-nucleotide-resolution nucleic acid structure mapping assay which uses DMS as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,RNA Ontology,,,,,,DMS structure mapping assay,,PMID:6159633 and PMID:2446263,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001015,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DMS structure mapping assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001671,electrophoretic mobility shift assay ,"EMSA,gel shift assay, gel mobility shift assay, band shift assay, gel retardation assay",is an assay which aims to provide information about Protein-DNA or Protein-RNA interaction and which used gel electrophoresis and relies on the fact the molecular interactions will cause the heterodimer to be retarded on the gel when compared to controls corresponding to protein extract alone and protein extract + neutral nucleic acid.,false,,,http://purl.obolibrary.org/obo/OBI_0000070|http://purl.obolibrary.org/obo/OBI_0001146,,,,"EMSA,gel shift assay, gel mobility shift assay, band shift assay, gel retardation assay",,,,,,,,,,,,,,,is an assay which aims to provide information about Protein-DNA or Protein-RNA interaction and which used gel electrophoresis and relies on the fact the molecular interactions will cause the heterodimer to be retarded on the gel when compared to controls corresponding to protein extract alone and protein extract + neutral nucleic acid.,PMID:6269071,,,,,,electrophoretic mobility shift assay ,,"Electrophoretic mobility shift assay reveals a novel recognition sequence for Setaria italica NAC protein.
Puranik S, Kumar K, Srivastava PS, Prasad M.
Plant Signal Behav. 2011 Oct;6(10):1588-90. Epub 2011 Oct 1.
PMID: 21918373",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001671,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,electrophoretic mobility shift assay ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra; Marcus Chibucos,,
http://purl.obolibrary.org/obo/IAO_0000104,plan specification,,"A directive information entity with action specifications and objective specifications as parts that, when concretized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified.|2/3/2009 Comment from OBI review.

Action specification not well enough specified.
Conditional specification not well enough specified.
Question whether all plan specifications have objective specifications.

Request that IAO either clarify these or change definitions not to use them",false,,,http://purl.obolibrary.org/obo/IAO_0000033,,,,,,,,,,,,,,,,,,,"A directive information entity with action specifications and objective specifications as parts that, when concretized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified.",OBI Plan and Planned Process branch|OBI_0000344,,,,,"2014-03-31: A plan specification can have other parts, such as conditional specifications.|2009-03-16: provenance: a term a plan was proposed for OBI (OBI_0000344) , edited by the PlanAndPlannedProcess branch. Original definition was "" a plan is a specification of a process that is realized by an actor to achieve the objective specified as part of the plan"". It has been subsequently moved to IAO where the objective for which the original term was defined was satisfied with the definitionof this, different, term.|Alternative previous definition: a plan is a set of instructions that specify how an objective should be achieved",plan specification,,PMID: 18323827.Nat Med. 2008 Mar;14(3):226.New plan proposed to help resolve conflicting medical advice.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000005|http://purl.obolibrary.org/obo/IAO_0000007,,,,,,,,,,,,,,,,IAO:0000104,,,,,,,,,,,,,,,,,,"2/3/2009 Comment from OBI review.

Action specification not well enough specified.
Conditional specification not well enough specified.
Question whether all plan specifications have objective specifications.

Request that IAO either clarify these or change definitions not to use them",,,,,,,,,,,,,,,,,,,,,,,,,,,,plan specification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0001719,assay measuring the association constant [KA] of a B cell epitope:antibody complex,association constant KA|binding assay|1/nM,A B cell epitope binding constant determination assay that measures the association constant KA.,false,,,http://purl.obolibrary.org/obo/OBI_0001709,,,,,,,,,,,,,,,,,,,A B cell epitope binding constant determination assay that measures the association constant KA.,IEDB,,,,,,assay measuring the association constant [KA] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001719,,,,,,,,,,,,,,,,,,,,,,,,association constant KA|binding assay|1/nM,,,,,,,,,,,,,,,,,,,,,,assay measuring the association constant [KA] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001349,cytometric bead array assay measuring epitope specific interleukin-13 production by T cells,IL-13 release|cytometric bead array,An assay of epitope specific interleukin-13 production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001251,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-13 production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific interleukin-13 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001349,,,,,,,,,,,,,,,,,,,,,,,,IL-13 release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific interleukin-13 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001582,obsolete cell bound MHC direct binding assay,cell bound MHC direct binding ,direct binding assay measuring MHC ligand binding using MHC derived from a cell,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,direct binding assay measuring MHC ligand binding using MHC derived from a cell,IEDB (QTT),,,,,,obsolete cell bound MHC direct binding assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,OBI:0001582,,,,,,,,,,,,,,,,,,,,,,,,cell bound MHC direct binding ,,,,,,,,,,,,,,,,,,,,,,obsolete cell bound MHC direct binding assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0400147,microarray,,A processed material that is made to be used in an analyte assay. It consists of a physical immobilisation matrix in which substances that bind the analyte are placed in regular spatial position.,false,,,http://purl.obolibrary.org/obo/OBI_0001865,,,,,,,,,,,,,,,,,,,A processed material that is made to be used in an analyte assay. It consists of a physical immobilisation matrix in which substances that bind the analyte are placed in regular spatial position.,PERSON: Chris Stoeckert,,,,,,microarray,,"An affymetrix U133 array is a microarray. Microarrays include 1 and 2-color arrays, custom and commercial arrays (e.g, Affymetrix, Agilent, Nimblegen, Illumina, etc.) for expression profiling, DNA variant detection, protein binding, and other genomic and functional genomic assays.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400147,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,microarray,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001456,biological activity assay measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells,CCL9/MIP-1g release|biological activity,A T cell epitope specific cytokine production assay that detects macrophage inflammatory protein-1 gamma production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects macrophage inflammatory protein-1 gamma production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001456,,,,,,,,,,,,,,,,,,,,,,,,CCL9/MIP-1g release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001556,cell lysate MHC direct binding assay of a MHC:ligand complex using radioactivity detection,qualitative binding|lysate MHC/direct/radioactivity,A cell lysate MHC binding assay that uses radioactivity detection to detect direct binding.,false,,,http://purl.obolibrary.org/obo/OBI_0001491|http://purl.obolibrary.org/obo/OBI_0001579,,,,,,,,,,,,,,,,,,,A cell lysate MHC binding assay that uses radioactivity detection to detect direct binding.,IEDB,,,,,,cell lysate MHC direct binding assay of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000201,,,,,,,,,,,,,,,,OBI:0001556,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|lysate MHC/direct/radioactivity,,,,,,,,,,,,,,,,,,,,,,cell lysate MHC direct binding assay of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0500016,fractional factorial design,,A fractional factorial design is_a study design in which only an adequately chosen fraction of the treatment combinations required for the complete factorial experiment is selected to be run,false,,,http://purl.obolibrary.org/obo/OBI_0500014,,,,,,,,,,,,,,,,,,,A fractional factorial design is_a study design in which only an adequately chosen fraction of the treatment combinations required for the complete factorial experiment is selected to be run,http://www.itl.nist.gov/div898/handbook/pri/section3/pri334.htm From ASQC (1983) Glossary & Tables for Statistical Quality Control,,,,,,fractional factorial design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500016,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,fractional factorial design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000011,planned process,,A processual entity that realizes a plan which is the concretization of a plan specification.,false,,,http://purl.obolibrary.org/obo/BFO_0000015,,,,,,,,,,,,,,,,,"This class merges the previously separated objective driven process and planned process, as they the separation proved hard to maintain. (1/22/09, branch call)|6/11/9: Edited at workshop. Used to include: is initiated by an agent",,A processual entity that realizes a plan which is the concretization of a plan specification.,branch derived,,,,,"'Plan' includes a future direction sense. That can be problematic if plans are changed during their execution. There are however implicit contingencies for protocols that an agent has in his mind that can be considered part of the plan, even if the agent didn't have them in mind before. Therefore, a planned process can diverge from what the agent would have said the plan was before executing it, by adjusting to problems encountered during execution (e.g. choosing another reagent with equivalent properties, if the originally planned one has run out.)|We are only considering successfully completed planned processes. A plan may be modified, and details added during execution. For a given planned process, the associated realized plan specification is the one encompassing all changes made during execution. This means that all processes in which an agent acts towards achieving some 
objectives is a planned process.",planned process,,Injecting mice with a vaccine in order to test its efficacy,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000011,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/obi.owl,,,,,,,,,,,,,,,,,,,planned process,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001119,cell harvester,,A device that is used to harvest cells from microplates and deposit samples on a filter mat. NOT AN INSTRUMENT?,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A device that is used to harvest cells from microplates and deposit samples on a filter mat. NOT AN INSTRUMENT?,PERSON: Erik Segerdell,,,,,,cell harvester,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0001043,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001119,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cell harvester,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/IAO_0000320,references section,,A part of a document that has citations as parts,false,,,http://purl.obolibrary.org/obo/IAO_0000314,,,,,,,,,,,,,,,,,,,A part of a document that has citations as parts,,,,,,,references section,,"The list of citations found at the end of a scientific publication, grant proposal or patent application, sometimes called ""literature cited"" or ""bibliography""",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000301,,,,,,,,,,,,,,,,IAO:0000320,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,references section,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0000549,column cartridger,,A chromatography device where the column cartridge is inserted into and stabilised.,false,,,http://purl.obolibrary.org/obo/OBI_0000485,,,,,,,,,,,,,,,,,check on definition !,,A chromatography device where the column cartridge is inserted into and stabilised.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01054,,,,,,column cartridger,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000549,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,column cartridger,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001505,purification,,"A planned process to separate a material entity into different compositions of which one or more have are purified fractions that contain higher concentration of a desired component, while others contain impurities and are not of interest",false,,,http://purl.obolibrary.org/obo/OBI_0600014,,,,,,,,,,,,,,,,,,,"A planned process to separate a material entity into different compositions of which one or more have are purified fractions that contain higher concentration of a desired component, while others contain impurities and are not of interest",MO_406 purify,,,,,,purification,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001505,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,purification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0400052,helium cadmium ion laser,,"A helium-cadmium laser is a metal vapor laser that emits wavelengths of 442, 325 and 354 nms. This laser is a metal vapor laser. A helium-cadmium laser can by used to irradiate cells in a flow cytometer.",false,,,http://purl.obolibrary.org/obo/OBI_0400073,,,,,,,,,,,,,,,,,,,"A helium-cadmium laser is a metal vapor laser that emits wavelengths of 442, 325 and 354 nms. This laser is a metal vapor laser. A helium-cadmium laser can by used to irradiate cells in a flow cytometer.",http://en.wikipedia.org/wiki/Laser#Gas_lasers,,,,,,helium cadmium ion laser,,KIMMON HeCd 325nm laser,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400052,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,helium cadmium ion laser,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0001996,chromatography assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex,dissociation constant KD|chromatography|nM,A B cell epitope equilibrium dissociation constant (KD) determination assay that uses an analytical chromatography assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001708,,,,,,,,,,,,,,,,,,,A B cell epitope equilibrium dissociation constant (KD) determination assay that uses an analytical chromatography assay.,IEDB,,,,,,chromatography assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001996,,,,,,,,,,,,,,,,,,,,,,,,dissociation constant KD|chromatography|nM,,,,,,,,,,,,,,,,,,,,,,chromatography assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0302874,edited document,,A document which is the output of a document editing process,false,,,http://purl.obolibrary.org/obo/IAO_0000310,,,,,,,,,,,,,,,,,,,A document which is the output of a document editing process,,,,,,,edited document,,The OBI manuscript is (much) edited imformation,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302874,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0302908,,,edited document,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra|Person:Bjoern Peters,,
http://www.geneontology.org/formats/oboInOwl#Synonym,Synonym,,,false,,,http://purl.obolibrary.org/obo/IAO_0000102,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,oboInOwl:Synonym,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000466,thermal conductivity detector,"TCD, hot wire detector","The most commonly used detector in preparative GC is the thermal conductivity detector (hot wire detector). Even this detector, however, is often too sensitive and has too high a flow impedance. Under such circumstances, the procedure mentioned above must be employed. The eluent from the preparative column is split and a small portion diverted through the detector (sometimes with further dilution with carrier gas to reduce sensitivity).",false,,,http://purl.obolibrary.org/obo/OBI_0000637,,,,"TCD, hot wire detector",,,,,,,,,,,,,,,"The most commonly used detector in preparative GC is the thermal conductivity detector (hot wire detector). Even this detector, however, is often too sensitive and has too high a flow impedance. Under such circumstances, the procedure mentioned above must be employed. The eluent from the preparative column is split and a small portion diverted through the detector (sometimes with further dilution with carrier gas to reduce sensitivity).",WEB:<http://www.chromatography-online.org/Preparative/Apparatus/Detectors/rs27.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01084,,,,,,thermal conductivity detector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000466,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,thermal conductivity detector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0302840,curated information,,A information content entity that has undergone a digital curation performed by a curator for accuracy checks and compliance with curation requirements. Information which has been assessed for accuracy by domain experts.,false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,,,,,,,,,,,,,,,,A information content entity that has undergone a digital curation performed by a curator for accuracy checks and compliance with curation requirements. Information which has been assessed for accuracy by domain experts.,OBI,,,,,"2010-01-31 Philippe Rocca-Serra: restriction now changed to be the output of a digital curation process + reflected in example of usage and reference|2009-11-10 Bjoern Peters. Need to check if this was intended. overlap with 'edited information', and has the same logical restrictions.",curated information,,PMID: 17344875: A curated compendium of phosphorylation motifs.Nat Biotechnol. 2007 Mar;25(3):285-6.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302840,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0302914,,,curated information,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Philippe Rocca-Serra|Person:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000485,chromatography instrument,,Any instrument that is used to carry out a chromatography experiment.,false,,,http://purl.obolibrary.org/obo/OBI_0000932,,,,,,,,,,,,,,,,,"chromatography device, defined class?",,Any instrument that is used to carry out a chromatography experiment.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01262,,,,,,chromatography instrument,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000372,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000485,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,chromatography instrument,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000539,imaging NMR probe,,An NMR probe that is designed for generating pictures from sample states via NMR imaging.,false,,,http://purl.obolibrary.org/obo/OBI_0000516,,,,,,,,,,,,,,,,,NMR device,,An NMR probe that is designed for generating pictures from sample states via NMR imaging.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400244,,,,,,imaging NMR probe,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000539,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,imaging NMR probe,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/CHEBI_59056,EDTA methidiumpropylamide,,"A combined intercalating and chelating reagent. The iron chelate, prepared by adding Fe(NH4)2(SO4)2, effects random oxidative cleavage of DNA in the presence of O2 and a reducing agent. This activity is useful as a footprinting probe.",false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,"A combined intercalating and chelating reagent. The iron chelate, prepared by adding Fe(NH4)2(SO4)2, effects random oxidative cleavage of DNA in the presence of O2 and a reducing agent. This activity is useful as a footprinting probe.",,,,,,,EDTA methidiumpropylamide,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:59056,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,EDTA methidiumpropylamide,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000991,Edinburgh score,,A score that measures the dominance of a person's right or left hand in everyday activities.,false,,,http://purl.obolibrary.org/obo/OBI_0000970,,,,,,,,,,,,,,,,,,,A score that measures the dominance of a person's right or left hand in everyday activities.,"PMID:5146491#Oldfield, R.C. (1971). The assessment and analysis of handedness: The Edinburgh inventory. Neuropsychologia, 9, 97-113|WEB:http://www.cse.yorku.ca/course_archive/2006-07/W/4441/EdinburghInventory.html",,,,,,Edinburgh score,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000991,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/PATO_0002201,,,,,http://purl.obolibrary.org/obo/OBI_0001001,,,Edinburgh score,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Jessica Turner|Person: Alan Ruttenberg,,
http://purl.obolibrary.org/obo/UBERON_0001013,adipose tissue,,Portion of connective tissue composed of adipocytes enmeshed in areolar tissue,false,,,http://purl.obolibrary.org/obo/CARO_0000055,,,,,,,,,,,,,,,,,,,Portion of connective tissue composed of adipocytes enmeshed in areolar tissue,,,,,,,adipose tissue,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UBERON:0001013,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uberon.owl,,,,,,,,,,,,,,,,,,,adipose tissue,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/IAO_0000035,obsolete_study interpretation,conclusion,"A study interpretation is a textual entity about the implications of a study result. Examples include discussion of whether a hypothesis is false, whether the study failed to address the hypothesis, and whether the study results have led to new hypotheses",true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,conclusion,,,,,,,,,,,,,,,"A study interpretation is a textual entity about the implications of a study result. Examples include discussion of whether a hypothesis is false, whether the study failed to address the hypothesis, and whether the study results have led to new hypotheses",OBI_0000005,,,,,"The obsoleting of narrative object required a modest change in the definition of this term.  Circularity with ""interpretation... interprets"" has been removed, using ""about the implications"" instead.|2009-03-16: work has been done on this term during during the OBI workshop winter 2009 and the current definition was considered acceptable for use in OBI. If there is a need to modify this definition please notify OBI.|2009-03-16: definition was ""A conclusion is a narrative object which can be published in a paper summerizing and interpreting a protocol application.""",obsolete_study interpretation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,IAO:0000035,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_study interpretation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Jennifer Fostel|Lawrence Hunter|PERSON: Melanie Courtot|PERSON: Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0001491,radioactivity detection binding assay,,binding assay that uses radioactivity detection as an indicator of binding,false,,,http://purl.obolibrary.org/obo/OBI_0001146,,,,,,,,,,,,,,,,,,,binding assay that uses radioactivity detection as an indicator of binding,IEDB,,,,,,radioactivity detection binding assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001491,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,radioactivity detection binding assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Bjoern Peters, Randi Vita",,
http://purl.obolibrary.org/obo/OBI_0001590,purified MHC direct binding assay measuring binding of a MHC:ligand complex using fluorescence detection,qualitative binding|purified MHC/direct/fluorescence,A purified MHC binding assay that uses fluorescence detection to measure direct ligand binding.,false,,,http://purl.obolibrary.org/obo/OBI_0001555|http://purl.obolibrary.org/obo/OBI_0001499,,,,,,,,,,,,,,,,,,,A purified MHC binding assay that uses fluorescence detection to measure direct ligand binding.,IEDB,,,,,,purified MHC direct binding assay measuring binding of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001501,,,,,,,,,,,,,,,,OBI:0001590,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|purified MHC/direct/fluorescence,,,,,,,,,,,,,,,,,,,,,,purified MHC direct binding assay measuring binding of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001977,cytometry assay,,An assay that measures properties of cells.,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,An assay that measures properties of cells.,IEDB,,,,,,cytometry assay,,An intracellular material detection by flow cytometry assay measuring peforin inside a culture of T cells.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001977,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cytometry assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001272,ELISPOT assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells,TNF release|ELISPOT,An assay of epitope specific tumor necrosis factor superfamily cytokine production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001400,,,,,,,,,,,,,,,,,,,An assay of epitope specific tumor necrosis factor superfamily cytokine production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001272,,,,,,,,,,,,,,,,,,,,,,,,TNF release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/EGO_0000000011,genomic location,,a site that indicates the location at a genome,false,,,http://purl.obolibrary.org/obo/BFO_0000029,,,,,,,,,,,,,,,,,,,a site that indicates the location at a genome,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,EGO:0000000011,,,,,,,,,,,,,,,,Oliver He,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,genomic location,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/EGO_0000000013,MAX binding in MCF-7 cell,,,false,,,http://purl.obolibrary.org/obo/EGO_0000000007,,,,,,,,,http://purl.obolibrary.org/obo/PR_P61244,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,EGO:0000000013,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,MAX binding in MCF-7 cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CLO_0007605,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/EGO_0000000010,mouse epigenome,,a eukaryotic epigenome that exists in mouse,false,,,http://purl.obolibrary.org/obo/EGO_0000000005,,,,,,,,,,,,,,,,,,,a eukaryotic epigenome that exists in mouse,WEB: https://en.wikipedia.org/wiki/Epigenome,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/NCBITaxon_10090,EGO:0000000010,http://purl.obolibrary.org/obo/NCBITaxon_10090,,,,,,,,,,,,,,,"Oliver He, Steve Qin, and Steve Pittard",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,mouse epigenome,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/EGO_0000000016,Pos 5 of human Chr I,,the position 5 in a genomic location in human chromosome I,false,,,http://purl.obolibrary.org/obo/EGO_0000000003,,,,,,,,,,,,,,,,,,,the position 5 in a genomic location in human chromosome I,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,EGO:0000000016,,,,,,,,,,,,,,,,Oliver He,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Pos 5 of human Chr I,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0400071,MACS Quant,,"A MACS Quant is a flow_cytometer_analyser manufactured by Miltenyi. It uses digital electronics, and has three lasers of wavelengths 405 nm, 488 nm, and 635 nm. It has filters and detectors to collect 7 fluorescent parameters and 2 scatter parameters. The MACS Quant is an analyser usually used in research applications.",false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,,,,,,,,,,,,,,,,"A MACS Quant is a flow_cytometer_analyser manufactured by Miltenyi. It uses digital electronics, and has three lasers of wavelengths 405 nm, 488 nm, and 635 nm. It has filters and detectors to collect 7 fluorescent parameters and 2 scatter parameters. The MACS Quant is an analyser usually used in research applications.",http://www.miltenyi.com,,,,,,MACS Quant,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400071,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,MACS Quant,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0000912,X-ray crystallography assay,,A 3D structure determination assay in which the diffraction of pattern of X-ray beams in a crystal of purified material entities is used to resolve the 3-dimensional structure of the material entity of interest.,false,,,http://purl.obolibrary.org/obo/OBI_0600045,,,,,,,,,,,,,,,,,,,A 3D structure determination assay in which the diffraction of pattern of X-ray beams in a crystal of purified material entities is used to resolve the 3-dimensional structure of the material entity of interest.,IEDB,,,,,,X-ray crystallography assay,,"Crystallizing an antibody:antigen complex, and recording the diffraction pattern of a synchrotron beam, and assembling the 3d complex structure based on homologous complexes.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000912,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,X-ray crystallography assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_1000207,assay bead,bead,A globular or round particle of defined physicochemical properties and size which can be exploited as either the primary substance for detection or as a secondary solid platform for the attachment of bioactive molecules.,false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,bead,,,,,,,,,,,,,,,A globular or round particle of defined physicochemical properties and size which can be exploited as either the primary substance for detection or as a secondary solid platform for the attachment of bioactive molecules.,,,,,,DS: Probably better modeled as a role.,assay bead,,Dynabeads are commercially available magnetic beads which are precoated with antibodies specific for select cellular receptors and are used to separate cell populations.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1000207,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,assay bead,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI,,
http://purl.obolibrary.org/obo/OBI_0001008,MPE-Fe(II) structure mapping assay,single nucleotide resolution mapping assay using Fe-MP probe,a single-nucleotide-resolution ribonucleic acid structure mapping assay which uses Fe-MP as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,false,,,http://purl.obolibrary.org/obo/OBI_0001017,,http://purl.obolibrary.org/obo/OBI_0000441,,single nucleotide resolution mapping assay using Fe-MP probe,,,,,,,,,,,,,,,a single-nucleotide-resolution ribonucleic acid structure mapping assay which uses Fe-MP as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,RNA ontology,,,,,,MPE-Fe(II) structure mapping assay,,PMID:6209709,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_33697,,,,OBI:0001008,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,MPE-Fe(II) structure mapping assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001288,ELISA measuring epitope specific lymphotoxin A production by T cells,lymphotoxin A/TNFb release|ELISA,An assay of epitope specific lymphotoxin A production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001327|http://purl.obolibrary.org/obo/OBI_0001246,,,,,,,,,,,,,,,,,,,An assay of epitope specific lymphotoxin A production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific lymphotoxin A production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001288,,,,,,,,,,,,,,,,,,,,,,,,lymphotoxin A/TNFb release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific lymphotoxin A production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001921,RNA-binding protein immunoprecipitation tiling array profiling,,A RNA-binding protein immunoprecipitation array profiling assay that combines immunoprecipitation of an RNA-binding protein and RNA tiling array  to identify mRNAs associated with selected RNA binding proteins (RBPs).,false,,,http://purl.obolibrary.org/obo/OBI_0001918,,,,,,,,,,,,,,,,,,,A RNA-binding protein immunoprecipitation array profiling assay that combines immunoprecipitation of an RNA-binding protein and RNA tiling array  to identify mRNAs associated with selected RNA binding proteins (RBPs).,Jain et al. RIP-Chip analysis: RNA-Binding Protein Immunoprecipitation-Microarray (Chip) Profiling. Methods Mol Biol. 2011;703:247-63. [PMID:21125495],,,,,,RNA-binding protein immunoprecipitation tiling array profiling,,Jain et al. RIP-Chip analysis: RNA-Binding Protein Immunoprecipitation-Microarray (Chip) Profiling. Methods Mol Biol. 2011;703:247-63. [PMID:21125495],,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001307,,,,,,,,,,,,,,,OBI:0001921,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,RNA-binding protein immunoprecipitation tiling array profiling,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/BFO_0000141,immaterial entity,,,false,,,http://purl.obolibrary.org/obo/BFO_0000004,,,,,,,ImmaterialEntity,immaterial,,,,,,,,,,,,,,,,,"BFO 2 Reference: Immaterial entities are divided into two subgroups:boundaries and sites, which bound, or are demarcated in relation, to material entities, and which can thus change location, shape and size and as their material hosts move or change shape or size (for example: your nasal passage; the hold of a ship; the boundary of Wales (which moves with the rotation of the Earth) [38, 7, 10",immaterial entity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000141,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,immaterial entity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000873,pre-mortem specimen,,a specimen that was taken from a live organism,false,,,http://purl.obolibrary.org/obo/OBI_0001506,,,,,,,,,,,,,,,,,,,a specimen that was taken from a live organism,MO_705 premortem,,,,,,pre-mortem specimen,,material obtained through a liver biopsy from a human patient,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000873,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,pre-mortem specimen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000619,chromatography splitter,,"An adjustable restriction that is placed in the waste outlet to allow the necessary pressure to develop at the column inlet to force a flow (q ml/min) through the column. If the flow of mobile phase is Q ml/min then the waste flow will be (Q-q) ml/min. by adjusting the waste flow, the proportion of the sample entering the capillary column can be varied over a wide range of values and the necessary minimum permissible volume for the particular column in use can be selected for analysis. Unfortunately, the fraction taken in this way may not be representative of the original sample. This is due to the individual solutes in the mixture having different diffusivities and, thus, they distribute themselves across the sampling tube in an irregular manner. In general, the components with higher diffusivities (e.g., those solutes of lower molecular weight) will diffuse away from the bulk sample more quickly than those having lower diffusivities.",false,,,http://purl.obolibrary.org/obo/OBI_0000048,,,,,,,,,,,,,,,,,chromatography device,,"An adjustable restriction that is placed in the waste outlet to allow the necessary pressure to develop at the column inlet to force a flow (q ml/min) through the column. If the flow of mobile phase is Q ml/min then the waste flow will be (Q-q) ml/min. by adjusting the waste flow, the proportion of the sample entering the capillary column can be varied over a wide range of values and the necessary minimum permissible volume for the particular column in use can be selected for analysis. Unfortunately, the fraction taken in this way may not be representative of the original sample. This is due to the individual solutes in the mixture having different diffusivities and, thus, they distribute themselves across the sampling tube in an irregular manner. In general, the components with higher diffusivities (e.g., those solutes of lower molecular weight) will diffuse away from the bulk sample more quickly than those having lower diffusivities.",WEB:<http://www.chromatography-online.org/EC-Dispersion/GC-Capillary-Columns/rs13.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01041,,,,,,chromatography splitter,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000619,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,chromatography splitter,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000747,material sample,sample population|sample,A material entity that has the material sample role,false,,,http://purl.obolibrary.org/obo/OBI_0100051|http://purl.obolibrary.org/obo/BFO_0000040,,,,sample population,,,,,,,,,,,,,,,A material entity that has the material sample role,,,,,,,material sample,,blood drawn from patient to measure his systemic glucose level. A population of humans with HIV enrolled in a study taken to represent patients with HIV in general.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000747,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sample,material sample,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI: workshop,,
http://purl.obolibrary.org/obo/OBI_0001948,sequence assembly name,assembly name,A textual entity that is used to denote a sequence assembly. ,false,,,http://purl.obolibrary.org/obo/IAO_0000300,,,,,,,,,,,,,,,,,,,A textual entity that is used to denote a sequence assembly. ,NIAID GSCID-BRC metadata working group,,,,,,sequence assembly name,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001948,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sequence assembly name,,,,,,assembly name,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Jie Zheng, Chris Stoeckert",,
http://purl.obolibrary.org/obo/CARO_0000043,portion of tissue,,"Anatomical structure, that consists of similar cells and intercellular matrix, aggregated according to genetically determined spatial relationships.",false,,,http://purl.obolibrary.org/obo/CARO_0001008,,,,,,,,,,,,,,,,,,,"Anatomical structure, that consists of similar cells and intercellular matrix, aggregated according to genetically determined spatial relationships.",,,,,,,portion of tissue,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CARO:0000043,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/caro.owl,,,,,,,,,,,,,,,,,,,portion of tissue,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000653,fuzzy clustering objective,,"A fuzzy clustering objective is a data transformation objective where the aim is to assign input objects (typically vectors of attributes) a probability that a point belongs to a class, where the number of class and their specifications are not known a priori.",false,,,http://purl.obolibrary.org/obo/OBI_0200166,,,,,,,,,,,,,,,,,,,"A fuzzy clustering objective is a data transformation objective where the aim is to assign input objects (typically vectors of attributes) a probability that a point belongs to a class, where the number of class and their specifications are not known a priori.",PERSON: Ryan Brinkman|PERSON: James Malone,,,,,,fuzzy clustering objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000653,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,fuzzy clustering objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0002027,Genome Analyzer IIe,Illumina Genome Analyzer IIe|Illumina GA IIe,"An Illumina Genome Analyzer II which is manufactured by the Illumina corporation. It supports sequencing of single, long or short insert paired end clone libraries relying on sequencing by synthesis technology. The Genome Analyzer IIe makes industry-leading next-generation sequencing technology accessible to more laboratories.",false,,,http://purl.obolibrary.org/obo/OBI_0000703,,,,Illumina Genome Analyzer IIe|Illumina GA IIe,,,,,,,,,,,,,,,"An Illumina Genome Analyzer II which is manufactured by the Illumina corporation. It supports sequencing of single, long or short insert paired end clone libraries relying on sequencing by synthesis technology. The Genome Analyzer IIe makes industry-leading next-generation sequencing technology accessible to more laboratories.",http://res.illumina.com/documents/products/datasheets/datasheet_genome_analyzer_iie.pdf,,,,,,Genome Analyzer IIe,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002027,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Genome Analyzer IIe,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000006,role of being consumer safety officer,,the role of a human being that is realized by enforcing regulations to ensure consumer safety,false,,,http://purl.obolibrary.org/obo/OBI_0000273,,,,,,,,,,,,,,,,,,,the role of a human being that is realized by enforcing regulations to ensure consumer safety,"OBI, CDISC",,,,,,role of being consumer safety officer,,"Person charged with serving as CSO, FDA official who coordinates the review|Consumer safety officer; Consumer Safety Officer Positions at FDA http://69.20.19.211/jobs/cso.htm",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000006,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,role of being consumer safety officer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel|Person:Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0001162,validation by reverse transcription PCR design,,a study design in which checks the accuracy or the quality of the result of an assay  by comparing with reverse transcription PCR results,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,a study design in which checks the accuracy or the quality of the result of an assay  by comparing with reverse transcription PCR results,MO_986 reverse_transcription_PCR_quality_control,,,,,,validation by reverse transcription PCR design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001162,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,validation by reverse transcription PCR design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000687,nucleotide overhang cloning,,Nucleotide overhang cloning is the process of inserting nucleic acid into a vector using nucleotide overhangs used to prevent self ligation,false,,,http://purl.obolibrary.org/obo/OBI_0600064,,,,,,,,,,,,,,,,,,,Nucleotide overhang cloning is the process of inserting nucleic acid into a vector using nucleotide overhangs used to prevent self ligation,,,,,,,nucleotide overhang cloning,,Cloning vectors are commercially available and supplied in linearized form with 3' dT overhangs,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000687,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,nucleotide overhang cloning,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0001759,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-X-C motif) ligand 12 production by T cells,CXCL12/SDF-1 release|RNA/DNA detection,An assay of epitope specific chemokine (C-X-C motif) ligand 12 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001776,,,,,,,,,,,,,,,,,,,An assay of epitope specific chemokine (C-X-C motif) ligand 12 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-X-C motif) ligand 12 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001759,,,,,,,,,,,,,,,,,,,,,,,,CXCL12/SDF-1 release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-X-C motif) ligand 12 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0500022,stopping rule,,a stopping rule (criterion) is_a *rule* which causes a *stopping process* to happen,false,,,http://purl.obolibrary.org/obo/IAO_0000055,,,,,,,,,,,,,,,,,,,a stopping rule (criterion) is_a *rule* which causes a *stopping process* to happen,PRS,,,,,,stopping rule,,"PMID: 17591081-BACKGROUND/AIMS: To investigate the viral kinetics of Chinese CHC patients received pegylated interferon plus ribavirin and examine the impact of HCV genotypes and severity of liver disease. METHODOLOGY: 65 treatment-naove CHC patients who finished a 24-week therapy with peginterferon (alpha-2b (1.5 mcg/kg/week) plus ribavirin (1000-1200 mg /day) and 24 weeks of follow-up were enrolled. Hepatic fibrosis was graded by the METAVIR scoring system. Serum quantitative HCV RNA was determined by Versant HCV RNA 3.0 assay (Bayer Inc.). RESULTS: Genotype non-1 patients responded quickly and a higher percentage of them achieved undetectable HCV RNA (< 615 IU/mL) at week 4 compared with genotype 1 patients (93% vs. 69%, p = 0.018). Degree of hepatic fibrosis significantly affected end-of-treatment and sustained response (SVR). For patients who did not achieve early virological response (EVR), the negative predictive value for SVR was 100%. In genotype 1 patients, undetectable HCV RNA by week 4 was a good marker to predict treatment response, with a positive predictive value of 84% and a negative predictive value of 82%. CONCLUSIONS: EVR can be applied to Chinese patients as an early stopping rule. A 24-week duration of pegylated IFN/ribavirin might be adequate for genotype 1 patients who rapidly responded to therapy.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500022,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,stopping rule,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PRS,,
http://purl.obolibrary.org/obo/OBI_0001102,electron paramagnetic resonance spectrometer,,"An spectrophotometer that is used to investigate chemical species that have one or more unpaired electrons, such as organic and inorganic free radicals or inorganic complexes possessing a transition metal ion.",false,,,http://purl.obolibrary.org/obo/OBI_0400115,,,,,,,,,,,,,,,,,,,"An spectrophotometer that is used to investigate chemical species that have one or more unpaired electrons, such as organic and inorganic free radicals or inorganic complexes possessing a transition metal ion.",http://en.wikipedia.org/wiki/Electron_paramagnetic_resonance,,,,,,electron paramagnetic resonance spectrometer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001102,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,electron paramagnetic resonance spectrometer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0000922,frozen specimen,,A specimen that has been frozen in order to store it.,false,,,http://purl.obolibrary.org/obo/OBI_0001472,,,,,,,,,,,,,,,,,,,A specimen that has been frozen in order to store it.,MO_610 frozen_sample,,,,,,frozen specimen,,Frozen blood plasma,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000922,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,frozen specimen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/IAO_0000323,author contributions section,,A part of a publication that is about the specific contributions of each author,false,,,http://purl.obolibrary.org/obo/IAO_0000314,,,,,,,,,,,,,,,,,,,A part of a publication that is about the specific contributions of each author,,,,,,,author contributions section,,"LH conceived of the hypothesis, designed the study and contributed to the writing of the manuscript.  KBC executed the experiments, analyzed the data, and contributed to the writing of the manuscript.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000323,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,author contributions section,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0001606,cell bound MHC direct binding assay of a MHC:ligand complex using fluorescence detection,qualitative binding|cellular MHC/direct/fluorescence,A cell bound MHC binding assay that uses fluorescence detection to detect direct binding.,false,,,http://purl.obolibrary.org/obo/OBI_0001550|http://purl.obolibrary.org/obo/OBI_0001499,,,,,,,,,,,,,,,,,,,A cell bound MHC binding assay that uses fluorescence detection to detect direct binding.,IEDB,,,,,,cell bound MHC direct binding assay of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001501,,,,,,,,,,,,,,,,OBI:0001606,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|cellular MHC/direct/fluorescence,,,,,,,,,,,,,,,,,,,,,,cell bound MHC direct binding assay of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0400014,BioSorter1000,,"A BioSorter1000 is a flow_cytometer_sorter manufactured by Union Biometrica. It includes analog electronics, 488/514 nm multi-line Argon-ion laser for fluorescence and a light stabilized 670 nm forward scatter laser for extinction and time-of-flight. It has filters and PMTs for 3 fluorescent parameters and photodiodes for scatter, time of flight, and extinction. The flow cell is quartz cuvette. The BioSorterTM 1000 is an instrument for analyzing and sorting objects from 200-600 microns in diameter.",false,,,http://purl.obolibrary.org/obo/OBI_0400099,,,,,,,,,,,,,,,,,,,"A BioSorter1000 is a flow_cytometer_sorter manufactured by Union Biometrica. It includes analog electronics, 488/514 nm multi-line Argon-ion laser for fluorescence and a light stabilized 670 nm forward scatter laser for extinction and time-of-flight. It has filters and PMTs for 3 fluorescent parameters and photodiodes for scatter, time of flight, and extinction. The flow cell is quartz cuvette. The BioSorterTM 1000 is an instrument for analyzing and sorting objects from 200-600 microns in diameter.",http://www.unionbio.com/products/BioSorter.html,,,,,,BioSorter1000,,BioSorter 1000 at TSRI Flow Cytometry Core Facility,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400014,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BioSorter1000,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0400018,Cell Lab Quanta SC,,"A Cell Lab Quanta SC is a flow_cytometer_analyser manufactured by Becman Coulter. It features a mercury arc lamp optimized at 366, 405, and 435 nm, and a 488 nm laser diode. It has filters and PMTs to collect up to 3 fluorescent parameters, and a photodiode for side scatter detection. This cytometer uses Couter-Volume for cell size measurements. The Cell Lab Quanta SC can be used for measuring the properties of individual cells.",false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,,,,,,,,,,,,,,,,"A Cell Lab Quanta SC is a flow_cytometer_analyser manufactured by Becman Coulter. It features a mercury arc lamp optimized at 366, 405, and 435 nm, and a 488 nm laser diode. It has filters and PMTs to collect up to 3 fluorescent parameters, and a photodiode for side scatter detection. This cytometer uses Couter-Volume for cell size measurements. The Cell Lab Quanta SC can be used for measuring the properties of individual cells.",http://www.beckmancoulter.com/cell-lab,,,,,,Cell Lab Quanta SC,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400018,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Cell Lab Quanta SC,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/IAO_0000186,photographic print,,A photographic print is a material entity upon which a photograph generically depends.,false,,,http://purl.obolibrary.org/obo/BFO_0000040|http://purl.obolibrary.org/obo/IAO_0000178,,,,,,,,,,,,,,,,,,,A photographic print is a material entity upon which a photograph generically depends.,,,,,,,photographic print,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000186,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,photographic print,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Alan Ruttenberg|PERSON:Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0200133,node out-degree calculation,,A node quality calculation in which an input data set describing object nodes and directional relationship edges between object nodes is used to enumerate the number of unique relationships pointing out of an individual object node.,false,,,http://purl.obolibrary.org/obo/OBI_0200129,,,,,,,,,,,,,,,,,,,A node quality calculation in which an input data set describing object nodes and directional relationship edges between object nodes is used to enumerate the number of unique relationships pointing out of an individual object node.,PERSON: Richard Scheuermann,,,,,,node out-degree calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200133,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,node out-degree calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Richard Scheuermann,,
http://purl.obolibrary.org/obo/OBI_0000594,column adapter,,An Adapter that enabled the connection of a column to additional devices.,false,,,http://purl.obolibrary.org/obo/OBI_0000048,,,,,,,,,,,,,,,,,chromatography device,,An Adapter that enabled the connection of a column to additional devices.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01113,,,,,,column adapter,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000594,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,column adapter,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/IAO_0000015,information carrier,,A quality of an information bearer that imparts the information content,false,,,http://purl.obolibrary.org/obo/BFO_0000019,,,,,,,,,,,,,,,,,,,A quality of an information bearer that imparts the information content,"Smith, Ceusters, Ruttenberg, 2000 years of philosophy",,,,,"2014-03-10: We are not certain that all information carriers are qualities. There was a discussion of dropping it.|12/15/09: There is a concern that some ways that carry information may be processes rather than qualities, such as in a 'delayed wave carrier'.",information carrier,,In the case of a printed paperback novel the physicality of the ink and of the paper form part of the information bearer. The qualities of appearing black and having a certain pattern for the ink and appearing white for the paper form part of the information carrier in this case.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000015,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,information carrier,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0000251,cluster,,A data set which is a subset of data that are a similar to each other in some way.,false,,,http://purl.obolibrary.org/obo/IAO_0000100,,,,,,,,,,,,,,,,,,,A data set which is a subset of data that are a similar to each other in some way.,group:OBI,,,,,,cluster,,Cluster of the lymphocytes population.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000251,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cluster,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Allyson|person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_1110174,intracellular cytokine staining assay measuring epitope specific tumor necrosis factor production by T cells,TNFa release|ICS,A T cell epitope specific tumor necrosis factor production assay that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001416|http://purl.obolibrary.org/obo/OBI_0001385,,,,,,,,,,,,,,,,,,,A T cell epitope specific tumor necrosis factor production assay that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific tumor necrosis factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110174,,,,,,,,,,,,,,,,,,,,,,,,TNFa release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific tumor necrosis factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000146,supernatant collection system harvesting frame,,"a device that is designed for collecting 90% of the supernatant in a microplate well and separating the living cell with no stress, eliminating centrifugation and other similar techniques. It can be used in a variety of release assays with different radioactive isotopes, such as Cr51 or I125.",false,,,http://purl.obolibrary.org/obo/OBI_0000967,,,,,,,,,,,,,,,,,,,"a device that is designed for collecting 90% of the supernatant in a microplate well and separating the living cell with no stress, eliminating centrifugation and other similar techniques. It can be used in a variety of release assays with different radioactive isotopes, such as Cr51 or I125.",google,,,,,,supernatant collection system harvesting frame,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000370,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000146,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,supernatant collection system harvesting frame,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000792,statistical model validation,,A data transformation which assesses how the results of a statistical analysis will generalize to an independent data set.,false,,,http://purl.obolibrary.org/obo/OBI_0200171,,,,,,,,,,,,,,,,,,,A data transformation which assesses how the results of a statistical analysis will generalize to an independent data set.,http://en.wikipedia.org/wiki/Cross-validation_%28statistics%29,,,,,,statistical model validation,,Using the expression levels of 20 proteins to predict whether a cancer patient will respond to a drug. A practical goal would be to determine which subset of the 20 features should be used to produce the best predictive model. - wikipedia,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000792,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,statistical model validation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_1110051,cultured CD8- T cell population,CD8- T cell culture sample,A T cell population characterized by not expressing the CD8 molecule on its surface.,false,,,http://purl.obolibrary.org/obo/OBI_0001875,,,,CD8- T cell culture sample,,,,,,,,,,,,,,,A T cell population characterized by not expressing the CD8 molecule on its surface.,IEDB,,,,,,cultured CD8- T cell population,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110051,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cultured CD8- T cell population,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000616,high resolution probe with automatic tuning and matching,"High Resolution Probes with Automatic Tuning and Matching, HR_probe_with_ATM","The Automatic Tuning and Matching (ATM) option for AVANCE spectrometers is available for double resonance probes in fixed-frequency and broadband tunable configurations with either direct or indirect detection. Thus, for multinuclear operation, as often required for applications in inorganic chemistry, ATM facilitates the accurate setting of 90 degree pulse widths on both observe and decoupling channels for each chosen nucleus and each individual sample - even with full automation. Triple resonance probes in fixed-frequency configurations, as typically used for inverse detection with high-field systems.",false,,,http://purl.obolibrary.org/obo/OBI_0000480,,,,"High Resolution Probes with Automatic Tuning and Matching, HR_probe_with_ATM",,,,,,,,,,,,,NMR probe,,"The Automatic Tuning and Matching (ATM) option for AVANCE spectrometers is available for double resonance probes in fixed-frequency and broadband tunable configurations with either direct or indirect detection. Thus, for multinuclear operation, as often required for applications in inorganic chemistry, ATM facilitates the accurate setting of 90 degree pulse widths on both observe and decoupling channels for each chosen nucleus and each individual sample - even with full automation. Triple resonance probes in fixed-frequency configurations, as typically used for inverse detection with high-field systems.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400224,,,,,,high resolution probe with automatic tuning and matching,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000616,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,high resolution probe with automatic tuning and matching,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001217,biological activity assay measuring epitope specific interleukin-22 production by T cells,IL-22 release|biological activity,A T cell epitope specific cytokine production assay that detects interleukin-22 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects interleukin-22 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific interleukin-22 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001217,,,,,,,,,,,,,,,,,,,,,,,,IL-22 release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific interleukin-22 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/GO_0006260,DNA replication,,"The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.",false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,"The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.",,,,,,,DNA replication,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0006260,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,DNA replication,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000105,transplantation,,a protocol application to replace an organ or tissue of an organism,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,a protocol application to replace an organ or tissue of an organism,OBI branch derived,,,,,,transplantation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000105,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,transplantation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0000248,feed role,feed,a role that inheres in a material entity and is realized in the use of that material entity by lab animal to provide all needed nourishment.,false,,,http://purl.obolibrary.org/obo/OBI_0000162,,,,feed,,,,,,,,,,,,,,,a role that inheres in a material entity and is realized in the use of that material entity by lab animal to provide all needed nourishment.,OBI,,,,,,feed role,,"Purina rat chow; cited use:  Control; F = feed (rat chow); W = water; F. g. = feed-ginger concentrate. www.academicjournals.org/AJB/PDF/pdf2007/19Sep/Egwurugwu%20et%20al.pdf -  Feb 29, 2008",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000248,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,feed role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0000507,gas generator,,"An instrument that generates gases for use with the gas chromatograph. Previously gas was obtained from gas tanks or gas cylinders. However, over the past decade the use of gas generators have become more popular as it avoids having gases at high pressure in the laboratory which is perceived by some as potentially dangerous. In addition, the use of a hydrogen generator avoids the use of a cylinder of hydrogen at high pressure which is also perceived by some as a serious fire hazard despite the fact that they have been used in laboratories, quite safely for nearly a century.",false,,,http://purl.obolibrary.org/obo/OBI_0000542,,,,,,,,,,,,,,,,,gas chromatography equipment,,"An instrument that generates gases for use with the gas chromatograph. Previously gas was obtained from gas tanks or gas cylinders. However, over the past decade the use of gas generators have become more popular as it avoids having gases at high pressure in the laboratory which is perceived by some as potentially dangerous. In addition, the use of a hydrogen generator avoids the use of a cylinder of hydrogen at high pressure which is also perceived by some as a serious fire hazard despite the fact that they have been used in laboratories, quite safely for nearly a century.",WEB:<http://www.chromatography-online.org/GC/Gas-Supplies/Pure-Air-Generators./rs5.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01033,,,,,,gas generator,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000507,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,gas generator,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000882,cell-cell killing assay,,A cytometry assay that monitors a cell population to track how many are killed by other cells.,false,,,http://purl.obolibrary.org/obo/OBI_0001977,,,,,,,,,,,,,,,,,,,A cytometry assay that monitors a cell population to track how many are killed by other cells.,IEDB,,,,,,cell-cell killing assay,,"Autologous EBV-transformed B-LCL were used as target cells for the influenza virus-specific CTL assays. Equal volumes of target and effector cells were added to tissue culture plates, and 1:2 serial dilutions of effectors were made. After a 4-h incubation of the effector cells with the target cells, supernatants were collected and counted with the LKB 1272 Clinigamma counter. Percent specific killing was determined with the following equation: (experimental 51Cr release - spontaneous 51Cr release)/(maximum 51Cr release - spontaneous 51Cr release) x 100.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000882,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cell-cell killing assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000635,JEOL CapNMR probe,,"The JEOL ECA and ECX NMR spectrometers now support the MRM/Protasis CapNMR Probe for well plate-based and microvial-based NMR analysis. The CapNMR probe is available at proton frequencies ranging from 300 MHz to 800 MHz in both indirect configurations (e.g. 1H{13C} and 1H {31P}) and also in triple resonance configurations (e.g. 1H{13C, 15N}, 1H{31P, 15N}). Both employ a high-strength z-directed field gradient. The flowprobes come with the choice of two flowcell volumes: a 5 μl flowcell with an NMR active volume of 2.5 μl, and a 10 μl flowcell with an NMR active volume of 5 μl. The fluidic connections are 75 μm i.d. and 1/32 o.d. FEP Teflon with hastelloy unions for exceptional solvent compatibility.",false,,,http://purl.obolibrary.org/obo/OBI_0000529,,,,,,,,,,,,,,,,,NMR probe,,"The JEOL ECA and ECX NMR spectrometers now support the MRM/Protasis CapNMR Probe for well plate-based and microvial-based NMR analysis. The CapNMR probe is available at proton frequencies ranging from 300 MHz to 800 MHz in both indirect configurations (e.g. 1H{13C} and 1H {31P}) and also in triple resonance configurations (e.g. 1H{13C, 15N}, 1H{31P, 15N}). Both employ a high-strength z-directed field gradient. The flowprobes come with the choice of two flowcell volumes: a 5 μl flowcell with an NMR active volume of 2.5 μl, and a 10 μl flowcell with an NMR active volume of 5 μl. The fluidic connections are 75 μm i.d. and 1/32 o.d. FEP Teflon with hastelloy unions for exceptional solvent compatibility.",WEB:<http://www.jeol.com/PRODUCTS/AnalyticalInstruments/NuclearMagneticResonance/CapNMRProbe/tabid/396/Default.aspx>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400233,,,,,,JEOL CapNMR probe,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000635,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,JEOL CapNMR probe,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000907,supplying,,"The planned process of providing material entities
to be used in an investigation.",false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,"5/31/2012: A supplying process implies that there is an acquisition process. These may need to be tied together, so that modeling either way is reciprocal. ",,"The planned process of providing material entities
to be used in an investigation.",Jennifer Fostel,,,,,,supplying,,Jackson Labs supplies mouse strains.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,OBI:0000907,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,supplying,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0001229,plasmon resonance assay measuring the dissociation constant [KD] of a T cell epitope:MHC:TCR complex,dissociation constant KD|surface plasmon resonance (SPR)|nM,A T cell epitope equilibrium dissociation constant (KD) determination assay that uses a surface plasmon resonance assay.,false,,,http://purl.obolibrary.org/obo/OBI_0002059,,,,,,,,,,,,,,,,,,,A T cell epitope equilibrium dissociation constant (KD) determination assay that uses a surface plasmon resonance assay.,IEDB,,,,,,plasmon resonance assay measuring the dissociation constant [KD] of a T cell epitope:MHC:TCR complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001229,,,,,,,,,,,,,,,,,,,,,,,,dissociation constant KD|surface plasmon resonance (SPR)|nM,,,,,,,,,,,,,,,,,,,,,,plasmon resonance assay measuring the dissociation constant [KD] of a T cell epitope:MHC:TCR complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001090,multimode microplate reader,,"A microplate reader that can detect multiple types of absorbance, luminescence or fluorescence.",false,,,http://purl.obolibrary.org/obo/OBI_0001058,,,,,,,,,,,,,,,,,,,"A microplate reader that can detect multiple types of absorbance, luminescence or fluorescence.",PERSON: Erik Segerdell,,,,,,multimode microplate reader,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001090,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,multimode microplate reader,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0600028,artificially induced reverse transcription,,a protocol with the objective to transcribe single-stranded RNA into complementary DNA (cDNA),false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,a protocol with the objective to transcribe single-stranded RNA into complementary DNA (cDNA),OBI branch derived,,,,,"We need to indicate the relationship between the cDNA generated and the RNA that was used as a template. This may be outside of the OBI scope|It could also be added that the reverse transcriptase is bearer of a GO:0003964 RNA-directed DNA polymerase activity, which is realized in this process.",artificially induced reverse transcription,,The use of M-MLV reverse transcriptase from the Moloney murine leukemia virus to transcribe an RNA sample into cDNA,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_33697|http://purl.obolibrary.org/obo/OBI_0000419,http://purl.obolibrary.org/obo/CHEBI_16991,,,OBI:0600028,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,artificially induced reverse transcription,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Kevin Clancy,,
http://purl.obolibrary.org/obo/OBI_0000456,material transformation objective,artifact  creation objective,an objective specifiction that creates an specific output object from input materials.,false,,,http://purl.obolibrary.org/obo/IAO_0000005,,,,artifact  creation objective,,,,,,,,,,,,,,,an objective specifiction that creates an specific output object from input materials.,GROUP: OBI PlanAndPlannedProcess Branch,,,,,,material transformation objective,,The objective to create a mouse infected with LCM virus. The objective to create a defined solution of PBS.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000456,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,material transformation objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot|PERSON: Jennifer Fostel|PERSON: Frank Gibson|PERSON: Bjoern Peters|PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000711,library preparation,library construction,is a process which results in the creation of a library from fragments of DNA using cloning vectors or oligonucleotides with the role of adaptors.,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,library construction,,,,,,,,,,,,,,,is a process which results in the creation of a library from fragments of DNA using cloning vectors or oligonucleotides with the role of adaptors.,,,,,,,library preparation,,"PMID: 19570239. Construction and analysis of cotton (Gossypium arboreum L.) drought-related cDNA library. Zhang L, Li FG, Liu CL, Zhang CJ, Zhang XY. BMC Res Notes. 2009 Jul 2;2:120.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000711,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,library preparation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001660,intracellular material detection assay measuring epitope specific granzyme A release by T cells,granzyme A release|intracellular staining,A T cell epitope specific granzyme A release assay that uses an intracellular material detection by flow cytometry assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001809,,,,,,,,,,,,,,,,,,,A T cell epitope specific granzyme A release assay that uses an intracellular material detection by flow cytometry assay.,IEDB,,,,,,intracellular material detection assay measuring epitope specific granzyme A release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001660,,,,,,,,,,,,,,,,,,,,,,,,granzyme A release|intracellular staining,,,,,,,,,,,,,,,,,,,,,,intracellular material detection assay measuring epitope specific granzyme A release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/IAO_0000097,obsolete_report table,,"A report table is a report display element consisting of a matrix of cells layed out in a grid, some set of which are filled with some information content",true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,"A report table is a report display element consisting of a matrix of cells layed out in a grid, some set of which are filled with some information content",group:OBI|OBI_0000265,,,,,2009-08-10 Alan Ruttenberg: Larry Hunter suggests that this be obsoleted and replaced by 'textual entity table'. Alan restored as there are OBI dependencies and this merits further discussion,obsolete_report table,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000002,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,IAO:0000097,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_report table,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Alan Ruttenberg|person:Allyson Lister,,
http://purl.obolibrary.org/obo/OBI_1110163,ELISA measuring epitope specific interleukin-18 production by T cells,IL-18 release|ELISA,An assay of epitope specific interleukin-18 production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001380,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-18 production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific interleukin-18 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110163,,,,,,,,,,,,,,,,,,,,,,,,IL-18 release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific interleukin-18 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000220,reference subject role,reference participant,a reference subject  role which inheres in an organism or entity of organismal origin so that the characteristics or responses of the participant playing the reference participant role are used for comparison or reference,false,,,http://purl.obolibrary.org/obo/OBI_0000097,,,,reference participant,,,,,,,,,,,,,,,a reference subject  role which inheres in an organism or entity of organismal origin so that the characteristics or responses of the participant playing the reference participant role are used for comparison or reference,OBI,,,,,,reference subject role,,Saline treated rat; one of three identically-treated subjects,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000220,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,reference subject role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel,,
http://purl.obolibrary.org/obo/IAO_0000325,footnote,endnote,A part of a document that is about a specific other part of the document.  Usually footnotes are spatially segregated from the rest of the document.,false,,,http://purl.obolibrary.org/obo/IAO_0000314,,,,endnote,,,,,,,,,,,,,,,A part of a document that is about a specific other part of the document.  Usually footnotes are spatially segregated from the rest of the document.,,,,,,,footnote,,"The referent in the text is usually indicated by a special typographic character such as * or a superscripted number, which is also used to indicate the footnote that refers to that text.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000325,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000314,,,,,,,,,,,,,,,,footnote,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0000877,cell line immortalization,'establishing immortal cell line through directed genetic modification',"an establishing cell line process whereby a mortal cell line is intentionally genetically modified to be capable of indefinite propagation and re-established as a new immortal cell line|A immortalizing genetic transformation of an existing population of cell line cells is required as part of this process, as are additional steps for  selecting and propagating the cells output form this process into a cell line.",false,,,http://purl.obolibrary.org/obo/OBI_0001867,,,,'establishing immortal cell line through directed genetic modification',,,,,,,,,,,,,,,an establishing cell line process whereby a mortal cell line is intentionally genetically modified to be capable of indefinite propagation and re-established as a new immortal cell line,OBI,,,,,"4-20-13 MHB: This class was repositioned as a child of 'establishing cell line', based on the existing definition (""the planned process of experimentally creating a cell line which is capable of dividing indefinitely in vitro""), and examples and other annotations indicating the intent to describe a process through which a new immortal cell line is established from an existing mortal cell line using genetic modification techniques.  The definition above was modified to clarify this perspective.",cell line immortalization,,Production of a cell line for the purposes of experimentation e.g. EBV transformation of PBMs,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001907,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CLO_0009828,,,OBI:0000877,,,,,,,,,,,,,,,,,,"A immortalizing genetic transformation of an existing population of cell line cells is required as part of this process, as are additional steps for  selecting and propagating the cells output form this process into a cell line.",,,,,,,,,,,,,,,,,,,,,,,,,,,,cell line immortalization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/IAO_0000038,graph,,A diagram that presents one or more tuples of information by mapping those tuples in to a two dimensional space in a non arbitrary way.,false,,,http://purl.obolibrary.org/obo/IAO_0000309,,,,,,,,,,,,,,,,,,,A diagram that presents one or more tuples of information by mapping those tuples in to a two dimensional space in a non arbitrary way.,OBI_0000240|group:OBI,,,,,,graph,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000038,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,graph,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Alan Ruttenberg|person:Allyson Lister|PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0000611,Varian NMR instrument,,An NMR instrument that is manufactured by Varian.,false,,,http://purl.obolibrary.org/obo/OBI_0000566,,,,,,,,,,,,,,,,,NMR instrument,,An NMR instrument that is manufactured by Varian.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400234,,,,,,Varian NMR instrument,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000611,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Varian NMR instrument,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000444,target of material addition role,,target of material addition role is a role realized by an entity into which a material is added in a material addition process,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,,,target of material addition role is a role realized by an entity into which a material is added in a material addition process,OBI,,,,,"From Branch discussion with BP, AR, MC -- there is a need for the recipient to interact with the administered material.  for example, a tooth receiving a filling was not considered to be a target role.",target of material addition role,,peritoneum of an animal receiving an interperitoneal injection; solution in a tube receiving additional material; location of absorbed material following a dermal application.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000444,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,target of material addition role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP:  Role Branch,,
http://purl.obolibrary.org/obo/OBI_1110187,epitope specific IL-10 release by T cells,,A biological process where T cells produce IL-10 resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/OBI_0001193|http://purl.obolibrary.org/obo/GO_0032613,,,,,,,,,,,,,,,,,,,A biological process where T cells produce IL-10 resulting from the recognition of a T cell epitope.,IEDB,,,,,,epitope specific IL-10 release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110187,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific IL-10 release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001902,sample preparation for sequencing assay,Nucleic Acid Preparation Method,A sample preparation for assay that preparation of nucleic acids for a sequencing assay,false,,,http://purl.obolibrary.org/obo/OBI_0000073,,,,,,,,,,,,,,,,,,,A sample preparation for assay that preparation of nucleic acids for a sequencing assay,NIAID GSCID-BRC metadata working group,,,,,,sample preparation for sequencing assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001902,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sample preparation for sequencing assay,,,,,,Nucleic Acid Preparation Method,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001874,random access memory size,,random access memory size is a scalar measurement datum which denotes the amount of physical memory know as random access memory present of a computer or required by a computational process or data transformation,false,,,http://purl.obolibrary.org/obo/IAO_0000032,,,,,,,,,,,,,,,,,,,random access memory size is a scalar measurement datum which denotes the amount of physical memory know as random access memory present of a computer or required by a computational process or data transformation,"PRS, AGB",,,,,,random access memory size,,"Gigascience. 2012 Dec 27;1(1):18. doi: 10.1186/2047-217X-1-18.
PMID: 23587118.
""However, the error correction module in SOAPdenovo was designed for short Illumina reads (35-50 bp), which consumes an excessive amount of computational time and memory on longer reads, for example, over 150 GB memory running for two days using 40-fold 100 bp paired-end Illumina HiSeq 2000 reads""",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001874,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,random access memory size,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Alejandra Gonzalez-Beltran|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001176,Individual epitope immunization in vivo,,An immunization in which an individual epitope is administered into a host organism. ,false,,,http://purl.obolibrary.org/obo/OBI_1110015,,,,,,,,,,,,,,,,,,,An immunization in which an individual epitope is administered into a host organism. ,,,,,,3/16/11 BP: This should have as a logical definition the exclusion that the immunogen cannot be something beyond the epitope itself. I don't know if that is possible to do here. ,Individual epitope immunization in vivo,,Injection of a peptide T cell epitope into a mouse,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001176,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Individual epitope immunization in vivo,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Bjoern Peters, Jason Greenbaum, Randi Vita",,
http://purl.obolibrary.org/obo/OBI_0302714,obsolete_collection (of entities of organismal origin),"set, group, ensemble","a collection is a bfo:aggregate object, that is a set of material object of the same kind",true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,"set, group, ensemble",,,,,,,,,,,,,"PRS: How can we distinguish with 'collection' as the process of collecting entities, (eg. data collection, urine collection)",,"a collection is a bfo:aggregate object, that is a set of material object of the same kind",PERSON: Philippe Rocca-Serra,,,,,"added during 22-02-2008 biomaterial call to distinguish library and population|2009-11-04, MC: Entity of organismal origin has been deprecated a while ago. We still have collection (of entities of organismal origin). I am not sure we could replace with collection of material entity without altering the meaning (i.e. deprecating the class). In addition, if we do deprecate that class, should we just assert the children under material entity?|03/17/2010: obsoleted (on call), and replaced by 'material entity' and/or specimen. No need for the 'collection' part of this class any more after merging bfo:aggregate object into material entity, and by dealing with 'specimen' rather than with entities of organismal origin.",obsolete_collection (of entities of organismal origin),,PMID: 18037794. Magn Reson Med Sci. 2007;6(3):139-46. Imaging of a large collection of human embryo using a super-parallel MR microscope.[the Orsay Museum has a nice collection of Impressionnist paintings],,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,OBI:0302714,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_collection (of entities of organismal origin),,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Susanna Sansone,,
http://purl.obolibrary.org/obo/OBI_0200149,unit-variance scaling,autoscaling,A unit-variance scaling is a data transformation that divides all measurements of a variable by the standard deviation of that variable.,false,,,http://purl.obolibrary.org/obo/OBI_0200169,,http://purl.obolibrary.org/obo/OBI_0200167,,autoscaling,,,,,,,,,,,,,,,A unit-variance scaling is a data transformation that divides all measurements of a variable by the standard deviation of that variable.,PMID:16762068,,,,,,unit-variance scaling,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200149,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,unit-variance scaling,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000476,manual injection system,,"The traditional hardware system that allows a human to inject a sample into an inlet by hand, using a syringe.",false,,,http://purl.obolibrary.org/obo/OBI_0000504,,,,,,,,,,,,,,,,,,,"The traditional hardware system that allows a human to inject a sample into an inlet by hand, using a syringe.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01064,,,,,,manual injection system,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000476,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,manual injection system,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001898,comment on investigation,Comments,A textual entity that is about any of the aspects of an investigation worth noting,false,,,http://purl.obolibrary.org/obo/IAO_0000300,,,,,,,,,,,,,,,,,,,A textual entity that is about any of the aspects of an investigation worth noting,NIAID GSCID-BRC metadata working group,,,,,,comment on investigation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001898,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,comment on investigation,,,,,,Comments,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/REO_0000280,molecular label,molecular tracer,"a molecular reagent intended to associate with some molecular target to serve as a proxy for the presence, abundance, or location of this target in a detection of molecular label assay",false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,molecular tracer,,,,,,,,,,,,,,,"a molecular reagent intended to associate with some molecular target to serve as a proxy for the presence, abundance, or location of this target in a detection of molecular label assay","OBI developer call, 3-12-12",,,,,,molecular label,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,REO:0000280,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/reo.owl,,,,,,,,,,,,,,,,,,,molecular label,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001986,immunohistochemistry,,An immunostaining assay to detect and potentially localize antigens within the cells of a tissue section.,false,,,http://purl.obolibrary.org/obo/OBI_0001632,,,,,,,,,,,,,,,,,,,An immunostaining assay to detect and potentially localize antigens within the cells of a tissue section.,IEDB,,,,,,immunohistochemistry,,Staining a brain tissue sample from an Alzheimer's disease patient with antibodies to amyloid beta to identify amyloid plaques.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001986,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,immunohistochemistry,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0500005,matched pairs design,,"A matched pair design is a study design which use groups of individuals associated (hence matched) to each other based on a set of criteria, one member going to one treatment, the other member receiving the other treatment.",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A matched pair design is a study design which use groups of individuals associated (hence matched) to each other based on a set of criteria, one member going to one treatment, the other member receiving the other treatment.",http://www.holah.karoo.net/experimentaldesigns.htm,,,,,,matched pairs design,,"PMID: 17288613-BSTRACT: BACKGROUND: Physicians in Canadian emergency departments (EDs) annually treat 185,000 alert and stable trauma victims who are at risk for cervical spine (C-spine) injury. However, only 0.9% of these patients have suffered a cervical spine fracture. Current use of radiography is not efficient. The Canadian C-Spine Rule is designed to allow physicians to be more selective and accurate in ordering C-spine radiography, and to rapidly clear the C-spine without the need for radiography in many patients. The goal of this phase III study is to evaluate the effectiveness of an active strategy to implement the Canadian C-Spine Rule into physician practice. Specific objectives are to: 1) determine clinical impact, 2) determine sustainability, 3) evaluate performance, and 4) conduct an economic evaluation. METHODS: We propose a matched-pair cluster design study that compares outcomes during three consecutive 12-months before, after, and decay periods at six pairs of intervention and control sites. These 12 hospital ED sites will be stratified as teaching or community hospitals, matched according to baseline C-spine radiography ordering rates, and then allocated within each pair to either intervention or control groups. During the after period at the intervention sites, simple and inexpensive strategies will be employed to actively implement the Canadian C-Spine Rule. The following outcomes will be assessed: 1) measures of clinical impact, 2) performance of the Canadian C-Spine Rule, and 3) economic measures. During the 12-month decay period, implementation strategies will continue, allowing us to evaluate the sustainability of the effect. We estimate a sample size of 4,800 patients in each period in order to have adequate power to evaluate the main outcomes. DISCUSSION: Phase I successfully derived the Canadian C-Spine Rule and phase II confirmed the accuracy and safety of the rule, hence, the potential for physicians to improve care. What remains unknown is the actual change in clinical behaviors that can be affected by implementation of the Canadian C-Spine Rule, and whether implementation can be achieved with simple and inexpensive measures. We believe that the Canadian C-Spine Rule has the potential to significantly reduce health care costs and improve the efficiency of patient flow in busy Canadian EDs.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500005,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,matched pairs design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000927,lyophilization storage,,"a storage process with input material entity and output freeze dried material for long time storage|can link to freezing-dying equipment, such as freeze-dryer, rotary evaporator, if needed",false,,,http://purl.obolibrary.org/obo/OBI_0302893,,http://purl.obolibrary.org/obo/OBI_0000806,,,,,,,,,,,,,,,,,a storage process with input material entity and output freeze dried material for long time storage,"",,,,,,lyophilization storage,,"",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,OBI:0000927,,,,,,,,,,,,,,,,,,"can link to freezing-dying equipment, such as freeze-dryer, rotary evaporator, if needed",,,,,,,,,,,,,,,,,,,,,,,,,,,,lyophilization storage,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Chris Stoeckert|PERSON: Jie Zheng,,
http://purl.obolibrary.org/obo/OBI_0001634,calorimetric binding assay,,"A binding assay in which the heat generated or absorbed during a binding event is measured, which allows determination of binding constants, reaction stoichiometry, enthalpy and entropy.",false,,,http://purl.obolibrary.org/obo/OBI_0001146,,,,,,,,,,,,,,,,,,,"A binding assay in which the heat generated or absorbed during a binding event is measured, which allows determination of binding constants, reaction stoichiometry, enthalpy and entropy.",IEDB,,,,,,calorimetric binding assay,,"A solution of a proteins is titrated into a solution containing a specific antibody. The heat released upon their interaction (ΔH) is monitored over time where each peak represents a heat change associated with the injection of a small volume of sample into the reaction cell. As successive amounts of the ligand are titrated into the cell, the quantity of heat absorbed or released is in direct proportion to the amount of binding. As the system reaches saturation, the heat signal diminishes until only heats of dilution are observed. A binding curve is then obtained from a plot of the heats from each injection against the ratio of protein and antibody in the cell . ",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001634,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,calorimetric binding assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000737,cloning vector,,"A cloning vector is an engineered material that is used as an input material for a recombinant vector cloning process to carry inserted nucleic acids. It contains an origin of replication for a specific destination host organism, encodes for a selectable gene product and contains a cloning site.",false,,,http://purl.obolibrary.org/obo/OBI_1110108|http://purl.obolibrary.org/obo/OBI_0000047|http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,"A cloning vector is an engineered material that is used as an input material for a recombinant vector cloning process to carry inserted nucleic acids. It contains an origin of replication for a specific destination host organism, encodes for a selectable gene product and contains a cloning site.",,,,,,,cloning vector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000737,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000094,,,cloning vector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001071,programmable array microscope,,A confocal microscope that uses a programmable spatial light modulator for generating an arbitrary pattern of conjugate illumination and detection apertures.,false,,,http://purl.obolibrary.org/obo/OBI_0001079,,,,,,,,,,,,,,,,,,,A confocal microscope that uses a programmable spatial light modulator for generating an arbitrary pattern of conjugate illumination and detection apertures.,"Verveer et al, Journal of Microscopy, vol. 189, pt. 3, pp. 192-8",,,,,,programmable array microscope,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001071,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,programmable array microscope,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001173,service,,A planned process in which a service provider performs a task (i.e. a planned process) for a service consumer.,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,,,A planned process in which a service provider performs a task (i.e. a planned process) for a service consumer.,OBI workshop San Diego 2011,,,,,,service,,providing a training course for UCSD employees how to run a DNA sequencer; sequencing a DNA sample provided by a service consumer restricted to non-human samples; giving access to tissue samples in a biobank within OHSU; JAX shipping mice from their colony ,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,OBI:0001173,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,service,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Carlo; Matt,,
http://purl.obolibrary.org/obo/UBERON_0005022,mucosa of nasopharynx,,A mucosa that is part of a nasopharynx [Automatically generated definition].,false,,,http://purl.obolibrary.org/obo/CARO_0000043,,,,,,,,,,,,,,,,,,,A mucosa that is part of a nasopharynx [Automatically generated definition].,,,,,,,mucosa of nasopharynx,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UBERON:0005022,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uberon.owl,,,,,,,,,,,,,,,,,,,mucosa of nasopharynx,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/UBERON_0005023,mucosa of oropharynx,,A mucosa that is part of a oropharynx [Automatically generated definition].,false,,,http://purl.obolibrary.org/obo/CARO_0000043,,,,,,,,,,,,,,,,,,,A mucosa that is part of a oropharynx [Automatically generated definition].,,,,,,,mucosa of oropharynx,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UBERON:0005023,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uberon.owl,,,,,,,,,,,,,,,,,,,mucosa of oropharynx,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/IAO_0000059,obsolete2_report figure,,"A report figure is a report display element that has some aspect of illustration, but may be a composite of figures, images, and other elements",true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,"A report figure is a report display element that has some aspect of illustration, but may be a composite of figures, images, and other elements",group:OBI|OBI_0000027,,,,,"Replaced by defined version of figure|I prepended the 'report ' to make it clear that we mean parts of reports here. We may want a more generic version of 'figure', in which case this would become a defined class - figure and part_of some report",obsolete2_report figure,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000124,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,IAO:0000059,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete2_report figure,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Alan Ruttenberg|person:Allyson Lister,,
http://purl.obolibrary.org/obo/OBI_0200110,s transformation,,"An s transformation is a data transformation obtained by applying the function S described in what follows to a (one dimensional) real number input. S(x)=T*exp(w-m)*(exp(x-w)-(p^2)*exp((w-x)/p)+p^2-1) if x>=w, S(x)=-S(w-x) otherwise; where exp denotes an exponential_transformations, 'p^' denotes the exponential transformation with base p; T, w, m, p are real constants with T, m, and p positive and w non-negative, and where w and p are related by w=2p*ln(p)(p+1) with the objective of normalization.",false,,,http://purl.obolibrary.org/obo/OBI_0200169,,http://purl.obolibrary.org/obo/OBI_0200167,,,,,,,,,,,,,,,,,"An s transformation is a data transformation obtained by applying the function S described in what follows to a (one dimensional) real number input. S(x)=T*exp(w-m)*(exp(x-w)-(p^2)*exp((w-x)/p)+p^2-1) if x>=w, S(x)=-S(w-x) otherwise; where exp denotes an exponential_transformations, 'p^' denotes the exponential transformation with base p; T, w, m, p are real constants with T, m, and p positive and w non-negative, and where w and p are related by w=2p*ln(p)(p+1) with the objective of normalization.",WEB: http://flowcyt.sourceforge.net/gating/latest.pdf,,,,,,s transformation,,This type of transformation is typically used in flow cytometry.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,s transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Ryan Brinkman|Joseph Spliden|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0001003,agar stab storage,,a storage process with input cell culture and agar and output agar stab for long time storage|need to specify that agar is one of input for this process,false,,,http://purl.obolibrary.org/obo/OBI_0302893,,http://purl.obolibrary.org/obo/OBI_0000806,,,,,,,,,,,,,,,,,a storage process with input cell culture and agar and output agar stab for long time storage,UPenn Group,,,,,,agar stab storage,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100060,,,,OBI:0001003,,,,,,,,,,,,,,,,,,need to specify that agar is one of input for this process,,,,,,,,,,,,,,,,,,,,,,,,,,,,agar stab storage,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Chris Stoeckert|PERSON: Jie Zheng,,
http://purl.obolibrary.org/obo/OBI_0000243,sponsor role,sponsor,"a responsible party role involved with any of the following activities:  initiating, managing and funding a study",false,,,http://purl.obolibrary.org/obo/OBI_0000102,,,,sponsor,,,,,,,,,,,,,"CDISC definition: sponsor. 1. An individual, company, institution, or organization that takes responsibility for the initiation, management, and/or financing of a clinical trial. 2. A corporation or agency whose employees conduct the investigation is considered a sponsor; employees are considered investigators",,"a responsible party role involved with any of the following activities:  initiating, managing and funding a study",,,,,,,sponsor role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000243,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sponsor role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jennifer Fostel,,
http://purl.obolibrary.org/obo/CL_0000097,mast cell,,"A cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. Progenitors leave bone marrow and mature in connective and mucosal tissue. Mature mast cells are found in all tissues, except the bloodstream. Their phenotype is CD117-high, CD123-negative, CD193-positive, CD200R3-positive, and FceRI-high. Stem-cell factor (KIT-ligand; SCF) is the main controlling signal of their survival and development.",false,,,http://purl.obolibrary.org/obo/CL_0000000,,,,,,,,,,,,,,,,,,,"A cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. Progenitors leave bone marrow and mature in connective and mucosal tissue. Mature mast cells are found in all tissues, except the bloodstream. Their phenotype is CD117-high, CD123-negative, CD193-positive, CD200R3-positive, and FceRI-high. Stem-cell factor (KIT-ligand; SCF) is the main controlling signal of their survival and development.",,,,,,,mast cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CL:0000097,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/cl.owl,,,,,,,,,,,,,,,,,,,mast cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0302892,enzymatic ligation,,An enzymatic ligation is a planned process in which molecules  are joined by covalent bonds through the action of an material entity with a ligase activity,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,An enzymatic ligation is a planned process in which molecules  are joined by covalent bonds through the action of an material entity with a ligase activity,OBI-Branch,,,,,,enzymatic ligation,,PMID: 17853876. Enzymatic ligation assisted by nucleases: simultaneous ligation and digestion promote the ordered assembly of DNA. Nat Protoc. 2007;2(9):2198-202.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302892,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,enzymatic ligation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001646,electron microscopy assay determining the 3D structure of a B cell epitope:antibody complex,3D structure|electron microscopy,A B cell epitope 3D structure determination assay that uses an electron microscopy imaging assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001721,,,,,,,,,,,,,,,,,,,A B cell epitope 3D structure determination assay that uses an electron microscopy imaging assay.,IEDB,,,,,,electron microscopy assay determining the 3D structure of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001646,,,,,,,,,,,,,,,,,,,,,,,,3D structure|electron microscopy,,,,,,,,,,,,,,,,,,,,,,electron microscopy assay determining the 3D structure of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001894,email address of sequencing facility contact person,Sequencing Facility Contact's email,An email address of the contact representative at the sequencing facility,false,,,http://purl.obolibrary.org/obo/IAO_0000429,,,,,,,,,,,,,,,,,,,An email address of the contact representative at the sequencing facility,NIAID GSCID-BRC metadata working group,,,,,,email address of sequencing facility contact person,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001894,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,email address of sequencing facility contact person,,,,,,Sequencing Facility Contact's email,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000407,viral RNA extraction,,The extraction of RNA from an input material that specifically isolates viral RNA,false,,,http://purl.obolibrary.org/obo/OBI_0666666,,,,,,,,,,,,,,,,,,,The extraction of RNA from an input material that specifically isolates viral RNA,,,,,,,viral RNA extraction,,"The AccuPrepTM Viral RNA Extraction Kit is designed for the rapid and convenient extraction of viral RNA from cell-free samples as serum, plasma, CSF, urine, etc - http://www.biokits.com/moreinfos.html?id=2703",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/NCBITaxon_10239,,,,OBI:0000407,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,viral RNA extraction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0200194,survival analysis data transformation,,A data transformation which has the objective of performing survival analysis.,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,A data transformation which has the objective of performing survival analysis.,PERSON: James Malone,,,,,,survival analysis data transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200194,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,survival analysis data transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0001588,binding,,The process of material entities forming complexes. ,false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,The process of material entities forming complexes. ,IEDB,,,,,9/28/11 BP: The disposition referenced is the one of the ligand to bind the molecule. This along with binding as a function / process needs to be figured out with GO which is inconsistent at this point. ,binding,,A peptide binding to an MHC molecule to form a complex. ,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001588,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,binding,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Bjoern Peters, Randi Vita",,
http://purl.obolibrary.org/obo/IAO_0000025,programming language,,"A language in which source code is written that is intended to be executed/run by a software interpreter. Programming languages are ways to write instructions that specify what to do, and sometimes, how to do it.",false,,,http://purl.obolibrary.org/obo/IAO_0000104,,,,,,,,,,,,,,,,,,,"A language in which source code is written that is intended to be executed/run by a software interpreter. Programming languages are ways to write instructions that specify what to do, and sometimes, how to do it.",OBI_0000058|group:OBI,,,,,,programming language,,"R, Perl, Java",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000025,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,programming language,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Alan Ruttenberg|person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0200071,loess transformation,,"A loess transformation is a data transformation that takes as input a collection of real number pairs (x, y) and, after performing (one or more) loess fittings, utilizes the resulting curves to transform each (x, y) in the input into (x, y-f(x)) where f(x) is one of the fitted curves.",false,,,http://purl.obolibrary.org/obo/OBI_0200169,,http://purl.obolibrary.org/obo/OBI_0200167,,,,,,,,,,,,,,,,,"A loess transformation is a data transformation that takes as input a collection of real number pairs (x, y) and, after performing (one or more) loess fittings, utilizes the resulting curves to transform each (x, y) in the input into (x, y-f(x)) where f(x) is one of the fitted curves.",OTHER: Editor's generalization based on MGED Ontology term,,,,,,loess transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200071,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,loess transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Melanie Courtot|Elisabetta Manduchi|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001451,biological activity assay measuring epitope specific interleukin-6 production by T cells,IL-6 release|biological activity,A T cell epitope specific cytokine production assay that detects interleukin-6 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects interleukin-6 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific interleukin-6 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001451,,,,,,,,,,,,,,,,,,,,,,,,IL-6 release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific interleukin-6 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/IAO_0000409,denotator type,,A denotator type indicates how a term should be interpreted from an ontological perspective.,false,,,http://purl.obolibrary.org/obo/IAO_0000102,,,,,,,,,,,,,,,,,,,A denotator type indicates how a term should be interpreted from an ontological perspective.,"Barry Smith, Werner Ceusters",,,,,,denotator type,,"The Basic Formal Ontology ontology makes a distinction between Universals and defined classes, where the formal are ""natural kinds"" and the latter arbitrary collections of entities.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000409,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,denotator type,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0200002,logistic-log curve fitting,,"A logistic-log curve fitting is a curve fitting where a curve of the form y=d+((a-d)/(1+(x/c)^b)) is obtained, where a, b, c, and d are determined so to optimize its fit to the input data points (x_1, y_1), (x_2, y_2), ..., (x_n, y_n).",false,,,http://purl.obolibrary.org/obo/OBI_0200072,,http://purl.obolibrary.org/obo/OBI_0200174,,,,,,,,,,,,,,,,,"A logistic-log curve fitting is a curve fitting where a curve of the form y=d+((a-d)/(1+(x/c)^b)) is obtained, where a, b, c, and d are determined so to optimize its fit to the input data points (x_1, y_1), (x_2, y_2), ..., (x_n, y_n).","ARTICLE: Plikaytis B.D. et al. (1991), J. Clin. Microbiol. 29(7): 1439-1448",,,,,,logistic-log curve fitting,,"Typically used in an enzyme-linked immunosorbent assay (ELISA) to model the relationship between optical density (OD) and dilution. In this case a and d correspond to the theoretical OD of the assay at zero and infinite concentrations, respectively; c is the dilution associated with the point of symmetry of the sigmoid and is located at the midpoint of the assay found at the inflection point of the curve; b is a curvature parameter and is related to the slope of the curve.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200002,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,logistic-log curve fitting,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Ryan Brinkman|Melanie Courtot|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0001881,organization of Bioinformatics Resource Center contact person,Bioinformatics Resource Center Contact's Institution,An organization that is the affiliation of the person who is contact representative of a Bioinformatics Resource Center,false,,,http://purl.obolibrary.org/obo/OBI_0000245,,,,,,,,,,,,,,,,,,,An organization that is the affiliation of the person who is contact representative of a Bioinformatics Resource Center,NIAID GSCID-BRC metadata working group,,,,,,organization of Bioinformatics Resource Center contact person,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001881,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,organization of Bioinformatics Resource Center contact person,,,,,,Bioinformatics Resource Center Contact's Institution,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001039,inline probing RNA structure mapping,,is a single-nucleotide-resolution ribonucleic acid structure mapping assay which uses intromolecular reactivity to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,false,,,http://purl.obolibrary.org/obo/OBI_0001017,,http://purl.obolibrary.org/obo/OBI_0000441,,,,,,,,,,,,,,,,,is a single-nucleotide-resolution ribonucleic acid structure mapping assay which uses intromolecular reactivity to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,RNA ontology,,,,,,inline probing RNA structure mapping,,PMID:10573122 and PMID: 18369975,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_33697,,,,OBI:0001039,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,inline probing RNA structure mapping,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0200145,intra subgraph connectivity calculation,,"A network subgraph quality calculation in which an input data set describing internal nodes, edges and node degrees is used to determine the average node degree within the subgraph.",false,,,http://purl.obolibrary.org/obo/OBI_0200137,,,,,,,,,,,,,,,,,,,"A network subgraph quality calculation in which an input data set describing internal nodes, edges and node degrees is used to determine the average node degree within the subgraph.",PERSON: Richard Scheuermann,,,,,,intra subgraph connectivity calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200145,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,intra subgraph connectivity calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Richard Scheuermann,,
http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,Obsolete Class,,,false,,,http://www.w3.org/2002/07/owl#Thing,,,,,,,,,,,,,,,,,,,,,,,,,,Obsolete Class,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,oboInOwl:ObsoleteClass,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Obsolete Class,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0400101,voltage amplifier,,A voltage amplifier is a device that amplifies the voltage signal.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A voltage amplifier is a device that amplifies the voltage signal.,http://en.wiktionary.org/wiki/amplifier,,,,,,voltage amplifier,,"Linear amplifier, log amplifier, microwave amplifier",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000395,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400101,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,voltage amplifier,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn|Frank Gibson,,
http://purl.obolibrary.org/obo/NCBITaxon_10239,Viruses,,,false,,,http://purl.obolibrary.org/obo/OBI_0100026,,,,,,,,,,,,,,,,,,,,,,,,,,Viruses,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:10239,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Viruses,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/IAO_0000078,curation status specification,,The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value.,false,,,http://purl.obolibrary.org/obo/IAO_0000102,,,,,,,,,,,,,,,,,,,The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value.,GROUP:OBI:<http://purl.obolibrary.org/obo/obi>|OBI_0000266,,,,,Better to represent curation as a process with parts and then relate labels to that process (in IAO meeting),curation status specification,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000078,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,curation status specification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Bill Bug,,
http://purl.obolibrary.org/obo/OBI_0400087,preamplifier,,A preamplifier is part of the electronics subsystem. It converts the current output from its associated detector to a voltage. The preamplifier is the first stage in analog electronics signal processing.,false,,,http://purl.obolibrary.org/obo/OBI_0400101,,,,,,,,,,,,,,,,,,,A preamplifier is part of the electronics subsystem. It converts the current output from its associated detector to a voltage. The preamplifier is the first stage in analog electronics signal processing.,"Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253",,,,,,preamplifier,,Built in preamplifier in a Hamamatsu H9656 PMT,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400087,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,preamplifier,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_1110130,biological activity assay measuring epitope specific T cell killing,cytotoxicity|biological activity,A T cell epitope dependent biological activity assay that detects the killing of an antigen presenting cell (APC) by a T cell whose TCR recognizes an epitope presented by the APC.,false,,,http://purl.obolibrary.org/obo/OBI_0002055,,,,,,,,,,,,,,,,,,,A T cell epitope dependent biological activity assay that detects the killing of an antigen presenting cell (APC) by a T cell whose TCR recognizes an epitope presented by the APC.,IEDB,,,,,,biological activity assay measuring epitope specific T cell killing,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110130,,,,,,,,,,,,,,,,,,,,,,,,cytotoxicity|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific T cell killing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001231,ELISA measuring epitope specific transforming growth factor-beta production by T cells,TGFb release|ELISA,An assay of epitope specific transforming growth factor-beta production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001264,,,,,,,,,,,,,,,,,,,An assay of epitope specific transforming growth factor-beta production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific transforming growth factor-beta production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001231,,,,,,,,,,,,,,,,,,,,,,,,TGFb release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific transforming growth factor-beta production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001605,binding on rate measurement datum (kon),,A rate measurement datum of how quickly bound complexes form,false,,,http://purl.obolibrary.org/obo/OBI_0001554|http://purl.obolibrary.org/obo/OBI_0001144,,,,,,,,,,,,,,,,,,,A rate measurement datum of how quickly bound complexes form,IEDB,,,,,,binding on rate measurement datum (kon),,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001605,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,binding on rate measurement datum (kon),,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Bjoern Peters, Randi Vita",,
http://purl.obolibrary.org/obo/OBI_0002044,RNA Bind-n-Seq assay,RNA Bind-n-Seq|RBNS|RNBS assay,A RNA-seq assay that comprehensively characterizes sequence and structural specificity of RNA binding proteins (RBPs),false,,,http://purl.obolibrary.org/obo/OBI_0001271,,,,RNA Bind-n-Seq|RBNS|RNBS assay,,,,,,,,,,,,,,,A RNA-seq assay that comprehensively characterizes sequence and structural specificity of RNA binding proteins (RBPs),"Lambert et al., (June 2014). ""RNA Bind-n-Seq: quantitative assessment of the sequence and structural binding specificity of RNA binding proteins."" Mol Cell. 2014 Jun 5;54(5):887-900. doi: 10.1016/j.molcel.2014.04.016",,,,,,RNA Bind-n-Seq assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002044,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,RNA Bind-n-Seq assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/BFO_0000040,material entity,,An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.,false,,,http://purl.obolibrary.org/obo/BFO_0000004,,,,,,,MaterialEntity,material,,,,,,,,,,,An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.,,,,,,"BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity.|BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60|BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here.",material entity,A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002]),an aggregate of human beings.|a forest fire|a tornado|a human being|an energy wave|the undetached arm of a human being|an epidemic|a flame|a photon|a sea wave|a puff of smoke|a hurricane,,,,,,,,(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] |(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] |(forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] ,every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])|Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002]),,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000040,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,material entity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000535,gel filtration column,,"A Gel filtration column is a chromatography column for size-exclusion chromatography, in which the stationary phase is a gel. The main application of gel filtration chromatography is the fractionation of proteins and other water-soluble polymers.",false,,,http://purl.obolibrary.org/obo/OBI_0000618,,,,,,,,,,,,,,,,,,,"A Gel filtration column is a chromatography column for size-exclusion chromatography, in which the stationary phase is a gel. The main application of gel filtration chromatography is the fractionation of proteins and other water-soluble polymers.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01104,,,,,,gel filtration column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000535,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,gel filtration column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001145,3D structure determination of bound complex assay,,A 3D structure determination assay in which a complex of 2 or more material enties is characterized which provides information on their binding configuration.,false,,,http://purl.obolibrary.org/obo/OBI_0600045|http://purl.obolibrary.org/obo/OBI_0001146,,,,,,,,,,,,,,,,,,,A 3D structure determination assay in which a complex of 2 or more material enties is characterized which provides information on their binding configuration.,IEDB,,,,,,3D structure determination of bound complex assay,,"Determination of a 3D structure of an antibody binding a protein by X-Ray crystallography, which identifies the specific binding site of the antibody.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001145,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,3D structure determination of bound complex assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000078,eMedical record,,An eMedical record is a digital document derived from a computer system used primarily for patient care in a clinical setting.  Not required to be compliant with requirements of 21 CFR Part 11.,false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,,,,,,,,,,,,,,,,An eMedical record is a digital document derived from a computer system used primarily for patient care in a clinical setting.  Not required to be compliant with requirements of 21 CFR Part 11.,article-without-pmid-or-doi:CDISCglossary,,,,,,eMedical record,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000078,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,eMedical record,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0000704,decision tree induction objective,,A decision tree induction objective is a data transformation objective in which a tree-like graph of edges and nodes is created and from which the selection of each branch requires that some type of logical decision is made.,false,,,http://purl.obolibrary.org/obo/OBI_0200166,,,,,,,,,,,,,,,,,,,A decision tree induction objective is a data transformation objective in which a tree-like graph of edges and nodes is created and from which the selection of each branch requires that some type of logical decision is made.,,,,,,,decision tree induction objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000704,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,decision tree induction objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0302859,genetically modified organism,,an organism that is the output of a genetic transformation process,false,,,http://purl.obolibrary.org/obo/OBI_0001151|http://purl.obolibrary.org/obo/OBI_0100026,,,,,,,,,,,,,,,,,,,an organism that is the output of a genetic transformation process,OBI Biomaterial,,,,,,genetically modified organism,,"A protocol for removal of antibiotic resistance cassettes from human embryonic stem cells genetically modified by homologous recombination or transgenesis.
Nat Protoc. 2008;3(10):1550-8. PMID: 18802436",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302859,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,genetically modified organism,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001968,operational taxonomic unit matrix,,"Operational Taxonomic Unit matrix  is a data item, organized as a table, where organismal taxonomic units, computed by sequence analysis and genetic distance calculation, are counted in a set of biological or environmental samples. The table is  used to appraise biodiversity of a population or community of living organism.
",false,,,http://purl.obolibrary.org/obo/IAO_0000027,,,,,,,,,,,,,,,,,,,"Operational Taxonomic Unit matrix  is a data item, organized as a table, where organismal taxonomic units, computed by sequence analysis and genetic distance calculation, are counted in a set of biological or environmental samples. The table is  used to appraise biodiversity of a population or community of living organism.
",PRS for OBI,,,,,,operational taxonomic unit matrix,,http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1610290/,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001968,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0200000,,,operational taxonomic unit matrix,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0002073,in vivo assay measuring T cell epitope specific protection from challenge,protection from challenge|in vivo assay,An efficacy of T cell epitope intervention experiment that uses a protection from challenge in vivo intervention experiment.,false,,,http://purl.obolibrary.org/obo/OBI_0001484,,,,,,,,,,,,,,,,,,,An efficacy of T cell epitope intervention experiment that uses a protection from challenge in vivo intervention experiment.,IEDB,,,,,,in vivo assay measuring T cell epitope specific protection from challenge,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002073,,,,,,,,,,,,,,,,,,,,,,,,protection from challenge|in vivo assay,,,,,,,,,,,,,,,,,,,,,,in vivo assay measuring T cell epitope specific protection from challenge,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/NCBITaxon_9606,Homo sapiens,human being|human|man,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_314146,,,,human being|human|man,,,,,,,,,,,,,,,,,,,,,,Homo sapiens,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:9606,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Homo sapiens,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000018,material supplier role,supplier|material provider role,"a role realized through the process of supplying materials such as animal subjects, reagents or other materials used in an investigation.",false,,,http://purl.obolibrary.org/obo/OBI_0000947,,,,supplier|material provider role,,,,,,,,,,,,,,,"a role realized through the process of supplying materials such as animal subjects, reagents or other materials used in an investigation.",,,,,,"Supplier role is a special kind of service, e.g. biobank",material supplier role,,Jackson Labs is an organization which provide mice as experimental material,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000018,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,material supplier role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0002074,in vitro assay measuring T cell epitope specific suppression,suppression|in vitro assay,T cell epitope dependent biological activity assay that detects suppression of an in vitro response.,false,,,http://purl.obolibrary.org/obo/OBI_0002055,,,,,,,,,,,,,,,,,,,T cell epitope dependent biological activity assay that detects suppression of an in vitro response.,IEDB,,,,,,in vitro assay measuring T cell epitope specific suppression,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002074,,,,,,,,,,,,,,,,,,,,,,,,suppression|in vitro assay,,,,,,,,,,,,,,,,,,,,,,in vitro assay measuring T cell epitope specific suppression,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, James Overton, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001432,operon identification design,,A study design that identifies locations and members of operons in a genome.,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,A study design that identifies locations and members of operons in a genome.,MO_772 operon_identification_design,,,,,,operon identification design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000113,,,,,,,,,,,,,,,,OBI:0001432,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,operon identification design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001553,assay measuring a binding constant of a MHC:ligand complex,binding constant|binding assay,A MHC:ligand binding assay that measures a binding constant.,false,,,http://purl.obolibrary.org/obo/OBI_1110126|http://purl.obolibrary.org/obo/OBI_0001025,,,,,,,,,,,,,,,,,,,A MHC:ligand binding assay that measures a binding constant.,IEDB,,,,,,assay measuring a binding constant of a MHC:ligand complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001553,,,,,,,,,,,,,,,,,,,,,,,,binding constant|binding assay,,,,,,,,,,,,,,,,,,,,,,assay measuring a binding constant of a MHC:ligand complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000937,obsolete_left handedness,,,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_left handedness,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000228,,,,,,,,,,,,,,,,,,OBI:0000937,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_left handedness,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0002008,Mouse 385K Whole Genome CGH Tiling Array,Nimblegen Mouse 385K Whole Genome CGH Tiling Array,"A tiling array which is manufactured by the Nimblegen corporation. Built to analyze DNA sequence copy number by comparative genomic hybridization for mouse DNA against 385,000 features.",false,,,http://purl.obolibrary.org/obo/OBI_0001307,,,,Nimblegen Mouse 385K Whole Genome CGH Tiling Array,,,,,,,,,,,,,,,"A tiling array which is manufactured by the Nimblegen corporation. Built to analyze DNA sequence copy number by comparative genomic hybridization for mouse DNA against 385,000 features.",http://www.nimblegen.com/downloads/support/05434483001_NG_CGHLOH_UGuide_v9p1.pdf,,,,,,Mouse 385K Whole Genome CGH Tiling Array,,"Miller, Becky Akiko. Detection and biological assessment of genome structural variation in Plasmodium falciparum. Diss. University of Notre Dame, 2012.  http://etd.nd.edu/ETD-db/theses/available/etd-04182012-114744/",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002008,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Mouse 385K Whole Genome CGH Tiling Array,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"PERSON: Venkat Malladi, Chris Stoeckert, Jie Zheng, Alan Ruttenberg",,
http://purl.obolibrary.org/obo/CHEBI_59051,diethyl pyrocarbonate,,The diethyl ester of dicarbonic acid.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,The diethyl ester of dicarbonic acid.,,,,,,,diethyl pyrocarbonate,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:59051,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,diethyl pyrocarbonate,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200081,sequence analysis objective,,A sequence analysis objective is a data transformation objective which aims to analyse some ordered biological data for sequential patterns.,false,,,http://purl.obolibrary.org/obo/OBI_0200166,,,,,,,,,,,,,,,,,,,A sequence analysis objective is a data transformation objective which aims to analyse some ordered biological data for sequential patterns.,PERSON: James Malone,,,,,,sequence analysis objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200081,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sequence analysis objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0000891,cell proliferation assay,,A cytometry assay which measures the degreee to which input cells are replicating.,false,,,http://purl.obolibrary.org/obo/OBI_0001977,,,,,,,,,,,,,,,,,,,A cytometry assay which measures the degreee to which input cells are replicating.,IEDB,,,,,,cell proliferation assay,,Measuring the amount of tritiated thymidine incorporated by dividing cells as a proxy for cell proliferation.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000891,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cell proliferation assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001216,cell culture analyte detection bioassay measuring epitope specific interleukin-2 production by T cells,IL-2 release|bioassay,An assay of epitope specific interleukin-2 production by T cells that uses a cell culture analyte detection bioassay.,false,,,http://purl.obolibrary.org/obo/OBI_0001445,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-2 production by T cells that uses a cell culture analyte detection bioassay.,IEDB,,,,,,cell culture analyte detection bioassay measuring epitope specific interleukin-2 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001216,,,,,,,,,,,,,,,,,,,,,,,,IL-2 release|bioassay,,,,,,,,,,,,,,,,,,,,,,cell culture analyte detection bioassay measuring epitope specific interleukin-2 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001438,ELISA measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells,CCL9/MIP-1g release|ELISA,An assay of epitope specific macrophage inflammatory protein-1 gamma production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001456,,,,,,,,,,,,,,,,,,,An assay of epitope specific macrophage inflammatory protein-1 gamma production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001438,,,,,,,,,,,,,,,,,,,,,,,,CCL9/MIP-1g release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000464,Bruker autosampler,,A Bruker autosampler is an autosampler made by Bruker.,false,,,http://purl.obolibrary.org/obo/OBI_0000555,,,,,,,,,,,,,,,,,,,A Bruker autosampler is an autosampler made by Bruker.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400209,,,,,,Bruker autosampler,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000464,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker autosampler,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001362,epitope specific chemokine (C-C motif) ligand 4 production by T cells,,A process of chemokine (C-C motif) ligand 4 production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0071606|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of chemokine (C-C motif) ligand 4 production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific chemokine (C-C motif) ligand 4 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001362,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific chemokine (C-C motif) ligand 4 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/PATO_0001741,radioactive,,A radiation quality inhering in bearer by virtue of the bearer's exhibiting or being caused by radioactivity.,false,,,http://purl.obolibrary.org/obo/BFO_0000016,,,,,,,,,,,,,,,,,,,A radiation quality inhering in bearer by virtue of the bearer's exhibiting or being caused by radioactivity.,,,,,,,radioactive,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001741,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,radioactive,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200179,class prediction objective,supervised classification objective|classification objective,"A class prediction objective (sometimes called supervised classification) is a data transformation objective where the aim is to create a predictor from training data through a machine learning technique. The training data consist of pairs of objects (typically vectors of attributes) and
class labels for these objects. The resulting predictor can be used to attach class labels to any valid novel input object. Depending on usage, the prediction can be definite or probabilistic. A classification is learned from the training data and can then be tested on test data.",false,,,http://purl.obolibrary.org/obo/OBI_0200166,,,,supervised classification objective|classification objective,,,,,,,,,,,,,,,"A class prediction objective (sometimes called supervised classification) is a data transformation objective where the aim is to create a predictor from training data through a machine learning technique. The training data consist of pairs of objects (typically vectors of attributes) and
class labels for these objects. The resulting predictor can be used to attach class labels to any valid novel input object. Depending on usage, the prediction can be definite or probabilistic. A classification is learned from the training data and can then be tested on test data.",PERSON: James Malone|PERSON: Elisabetta Manduchi,,,,,,class prediction objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200179,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,class prediction objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0001814,ELISA measuring epitope specific interleukin-27 production by T cells,IL-27 release|ELISA,An assay of epitope specific interleukin-27 production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001198,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-27 production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific interleukin-27 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001814,,,,,,,,,,,,,,,,,,,,,,,,IL-27 release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific interleukin-27 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/IAO_0000330,copyright section,,A document part that describes  legal restrictions on making or distributing copies of the document,false,,,http://purl.obolibrary.org/obo/IAO_0000314,,,,,,,,,,,,,,,,,,,A document part that describes  legal restrictions on making or distributing copies of the document,,,,,,,copyright section,,This work is licensed under a Creative Commons Attribution-Share Alike 3.0 United States License.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000330,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,copyright section,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0000242,software testing objective,,"Software_testing_objective is a hardware_optimization role describing a study designed to examine the effects of using different software or software parameters, e.g. data processing software.",false,,,http://purl.obolibrary.org/obo/OBI_0000208,,,,,,,,,,,,,,,,,,,"Software_testing_objective is a hardware_optimization role describing a study designed to examine the effects of using different software or software parameters, e.g. data processing software.",,,,,,,software testing objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000242,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,software testing objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel,,
http://purl.obolibrary.org/obo/BFO_0000038,one-dimensional temporal region,,,false,,,http://purl.obolibrary.org/obo/BFO_0000008,,,,,,,OneDimensionalTemporalRegion,1d-t-region,,,,,,,,,,,,,,,,,"BFO 2 Reference: A temporal interval is a special kind of one-dimensional temporal region, namely one that is self-connected (is without gaps or breaks).",one-dimensional temporal region,A one-dimensional temporal region is a temporal region that is extended. (axiom label in BFO2 Reference: [103-001]),the temporal region during which a process occurs.,,,,,,,,(forall (x) (if (OneDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [103-001] ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000038,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,one-dimensional temporal region,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/NCBITaxon_716545,saccharomyceta,,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_4890,,,,,,,,,,,,,,,,,,,,,,,,,,saccharomyceta,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:716545,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,saccharomyceta,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000405,primer role,,a complementary nucleotide probe role which inheres in nucleic acid molecular entity and is realized by the use of the entity bearing the role to initiate chain elongation.,false,,,http://purl.obolibrary.org/obo/OBI_0000857,,,,,,,,,,,,,,,,,,,a complementary nucleotide probe role which inheres in nucleic acid molecular entity and is realized by the use of the entity bearing the role to initiate chain elongation.,"(cell and molecular biology) A short strand of RNA that is synthesized along single-stranded DNA during replication, initiating DNA polymerase-catalyzed synthesis of the complementary strand. http://www.answers.com/topic/rna-primer",,,,,,primer role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000405,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,primer role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001113,microplate washer,,A device that is used to wash immunoassays in microwell strips and plates with professional accuracy. WHAT IS PROFESSIONAL ACCURACY??,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A device that is used to wash immunoassays in microwell strips and plates with professional accuracy. WHAT IS PROFESSIONAL ACCURACY??,http://www.articlesnatch.com/Article/Microplate-Readers-And-Washers-For-Laboratories/948037,,,,,,microplate washer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000379,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001113,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,microplate washer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0000934,intramuscular injection,,is the injection of a material entity (bearing the administered substance role) into the muscle (bearing the target role) of an organism using a syringe,false,,,http://purl.obolibrary.org/obo/OBI_0000426|http://purl.obolibrary.org/obo/OBI_0600007,,http://purl.obolibrary.org/obo/OBI_0000434,,,,,,,,,,,,,,,,,is the injection of a material entity (bearing the administered substance role) into the muscle (bearing the target role) of an organism using a syringe,,,,,,,intramuscular injection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000934,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,intramuscular injection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000790,recombinant BAC cloning,,Recombinant BAC cloning is a  process with the objective to insert genetic material into an F plasmid based bacterial artificial chromosome for future replication of the inserted material,false,,,http://purl.obolibrary.org/obo/OBI_0600064,,,,,,,,,,,,,,,,,,,Recombinant BAC cloning is a  process with the objective to insert genetic material into an F plasmid based bacterial artificial chromosome for future replication of the inserted material,http://en.wikipedia.org/wiki/Bacterial_artificial_chromosome,,,,,,recombinant BAC cloning,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000790,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,recombinant BAC cloning,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000903,in vitro cell killing assay,,A cell killing assay that measures if and how many target cells are actively killed by other cells in a cell culture.,false,,,http://purl.obolibrary.org/obo/OBI_0000882,,,,,,,,,,,,,,,,,,,A cell killing assay that measures if and how many target cells are actively killed by other cells in a cell culture.,IEDB,,,,,,in vitro cell killing assay,,"Autologous EBV-transformed B-LCL were used as target cells for the influenza virus-specific CTL assays. Equal volumes of target and effector cells were added to tissue culture plates, and 1:2 serial dilutions of effectors were made. After a 4-h incubation of the effector cells with the target cells, supernatants were collected and counted with the LKB 1272 Clinigamma counter. Percent specific killing was determined with the following equation: (experimental 51Cr release - spontaneous 51Cr release)/(maximum 51Cr release - spontaneous 51Cr release) x 100.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000903,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,in vitro cell killing assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0400148,DNA microarray,DNA Chip|DNA-array,A DNA-microarray is a microarray that is used as a physical 2D immobilisation matrix for DNA sequences. DNA microarray-bound DNA fragments are used as targets for a hybridising probed sample.,false,,,http://purl.obolibrary.org/obo/OBI_0400147,,,,DNA Chip|DNA-array,,,,,,,,,,,,,,,A DNA-microarray is a microarray that is used as a physical 2D immobilisation matrix for DNA sequences. DNA microarray-bound DNA fragments are used as targets for a hybridising probed sample.,Web:<http://en.wikipedia.org/wiki/DNA_microarray>@2008/03/03,,,,,,DNA microarray,,"Moran G, Stokes C, Thewes S, Hube B, Coleman DC, Sullivan D (2004). ""Comparative genomics using Candida albicans DNA microarrays reveals absence and divergence of virulence-associated genes in Candida dubliniensis"". Microbiology 150: 3363-3382. doi:10.1099/mic.0.27221-0. PMID 15470115",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400148,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNA microarray,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Daniel Schober|PERSON: Frank Gibson,,
http://purl.obolibrary.org/obo/OBI_0400106,centrifuge,,A device with a rapidly rotating container that applies centrifugal force to its contents,false,,,http://purl.obolibrary.org/obo/OBI_0000832|http://purl.obolibrary.org/obo/OBI_0000932,,,,,,,,,,,,,,,,,,,A device with a rapidly rotating container that applies centrifugal force to its contents,http://en.wikipedia.org/wiki/Centrifuge,,,,,,centrifuge,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400106,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,centrifuge,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Melanie Courtot|Trish Whetzel|Person: Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0000899,organellar RNA extract,,"A RNA extract that is the output of an extraction process in which RNA molecules found in an organelle, e.g., mitochondrion, ER, or chloroplast, excluding the nucleus, are extracted.",false,,,http://purl.obolibrary.org/obo/OBI_0000880,,,,,,,,,,,,,,,,,,,"A RNA extract that is the output of an extraction process in which RNA molecules found in an organelle, e.g., mitochondrion, ER, or chloroplast, excluding the nucleus, are extracted.",UPenn Group,,,,,,organellar RNA extract,,Extraction of organellar RNA from plant cells using organellar RNA binding protein.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000899,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000849,,,organellar RNA extract,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Chris Stoeckert|PERSON: Jie Zheng,,
http://purl.obolibrary.org/obo/OBI_0000910,radio immuno assay,,An assay in which a radioactive labeled antigen or antibody is used to determine the interaction between an antigen and its receptor. This can be used to detect the presence of an antigen of interest in an input sample or determine the specificity of an input antibody.,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,An assay in which a radioactive labeled antigen or antibody is used to determine the interaction between an antigen and its receptor. This can be used to detect the presence of an antigen of interest in an input sample or determine the specificity of an input antibody.,IEDB,,,,,,radio immuno assay,,"To evaluate the specificity of antibody binding to 35S-labeled IA-2(256–760) in comparison with 35S-labeled IA-2IC construct, the mutual inhibition activity of different concentrations of unlabeled IA-2IC and/or IA-2(256–760) fragments were tested. Unlabeled recombinant IA-2(256–760) and/or IA-2IC (0.5-, 1-, 2-, and 4-fold the amount of 35S-labeled protein) were added to each tube and incubated overnight at 4°C with patient sera. The following day, after incubation with radiolabeled 35S–IA-2(256–760) or 35S–IA-2IC proteins, samples were processed with the usual radioimmunoprecipitation assay.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000201,,,,,,,,,,,,,,,,OBI:0000910,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,radio immuno assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001949,sequence annotation reporting role,,A reporting party role that is realized by a person or organization who reports the feature annotation results from the analysis of a macromolecular sequence.,false,,,http://purl.obolibrary.org/obo/OBI_0000068,,,,,,,,,,,,,,,,,,,A reporting party role that is realized by a person or organization who reports the feature annotation results from the analysis of a macromolecular sequence.,NIAID GSCID-BRC metadata working group,,,,,,sequence annotation reporting role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001949,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sequence annotation reporting role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Jie Zheng, Chris Stoeckert",,
http://purl.obolibrary.org/obo/OBI_0001969,biodiversity assessment objective,,biodiversity assessment objective is an objective of a planned process aimed at producing data item whose interpretation should provide insight about variety of biological species found in a biological sample at macroscopic or microscopic level,false,,,http://purl.obolibrary.org/obo/OBI_0000015,,,,,,,,,,,,,,,,,,,biodiversity assessment objective is an objective of a planned process aimed at producing data item whose interpretation should provide insight about variety of biological species found in a biological sample at macroscopic or microscopic level,PRS for OBI,,,,,,biodiversity assessment objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001969,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,biodiversity assessment objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0200050,dimensionality reduction,data projection,"A dimensionality reduction is data partitioning which transforms each input m-dimensional vector (x_1, x_2, ..., x_m) into an output n-dimensional vector (y_1, y_2, ..., y_n), where n is smaller than m.",false,,,http://purl.obolibrary.org/obo/OBI_0200175,,,,data projection,,,,,,,,,,,,,,,"A dimensionality reduction is data partitioning which transforms each input m-dimensional vector (x_1, x_2, ..., x_m) into an output n-dimensional vector (y_1, y_2, ..., y_n), where n is smaller than m.",PERSON: Elisabetta Manduchi|PERSON: James Malone|PERSON: Melanie Courtot,,,,,,dimensionality reduction,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200050,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,dimensionality reduction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Melanie Courtot|Elisabetta Manduchi|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000854,western blot analysis,,"An analyte assay that detects specific peptides in an input material by separating it using gel electrophoresis, transfering the separated molecules to a membrane, and staining them with  antibodies specific to the analyte molecules.",false,,,http://purl.obolibrary.org/obo/OBI_0001978,,,,,,,,,,,,,,,,,,,"An analyte assay that detects specific peptides in an input material by separating it using gel electrophoresis, transfering the separated molecules to a membrane, and staining them with  antibodies specific to the analyte molecules.","Philippe Rocca-Serra, IEDB",,,,,,western blot analysis,,"Running a cell lysate on an acrylamide gel in a western blot aparatus to separate the constituent proteins, followed by transfer of the proteins from the gel to a nitrocellulose membrane. Staining this membrane with specific antibodies to detect the presence of specific proteins of interest.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000854,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,western blot analysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Philippe Rocca-Serra, IEDB",,
http://purl.obolibrary.org/obo/OBI_0100014,chimera,,An organism which contains cells or tissues with a different genotype,false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,An organism which contains cells or tissues with a different genotype,GROUP: OBI,,,,,,chimera,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0100014,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,chimera,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0000503,Bruker LC-NMR platform,,The LC-NMR/MS setup was first introduced by Bruker BioSpin in 1999. An LC-NMR system including a Bruker Peak Sampling Unit (BPSU-36) was coupled with a Bruker Daltonics esquire series ion trap mass spectrometer via a Bruker NMR-MS interface (BNMI). Since October 2004 the Bruker Daltonics microTOF-LC time-of-flight mass spectrometer can also be integrated in an LC-NMR setup.,false,,,http://purl.obolibrary.org/obo/OBI_0000596,,,,,,,,,,,,,,,,,NMR instrument|hyphenated NMR instrument platform,,The LC-NMR/MS setup was first introduced by Bruker BioSpin in 1999. An LC-NMR system including a Bruker Peak Sampling Unit (BPSU-36) was coupled with a Bruker Daltonics esquire series ion trap mass spectrometer via a Bruker NMR-MS interface (BNMI). Since October 2004 the Bruker Daltonics microTOF-LC time-of-flight mass spectrometer can also be integrated in an LC-NMR setup.,WEB:<http://www.bruker-biospin.com/hyphenation_lcnmr_ms.html>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400276,,,,,,Bruker LC-NMR platform,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000503,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker LC-NMR platform,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001946,forward PCR primer,sense primer|5' primer|forward primer,"A short oligonucleotide complementary to target DNA (5'->3' on plus strand) that acts as the leader for DNA extension in a PCR reaction. The polymerase starts replication at the 3'-end of the primer, and copies the opposite strand. A primer is characterized by its 'melting temperature' (Tm) and pairs of primers should have similar Tm.",false,,,http://purl.obolibrary.org/obo/CHEBI_16991|http://purl.obolibrary.org/obo/OBI_0001879,,,,sense primer|5' primer|forward primer,,,,,,,,,,,,,,,"A short oligonucleotide complementary to target DNA (5'->3' on plus strand) that acts as the leader for DNA extension in a PCR reaction. The polymerase starts replication at the 3'-end of the primer, and copies the opposite strand. A primer is characterized by its 'melting temperature' (Tm) and pairs of primers should have similar Tm.",adapted from http://www.ncbi.nlm.nih.gov/projects/genome/probe/doc/Glossary.shtml#p,,,,,,forward PCR primer,,"SP6 promoter, forward primer (SP6 TTTAGGTGACACTATAG)",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001946,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,forward PCR primer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000501,variable wavelength detector,,"A chromatography detector, that can detect signals within a certain range at user-defined wavelengths.",false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,"A chromatography detector, that can detect signals within a certain range at user-defined wavelengths.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01079,,,,,,variable wavelength detector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000501,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,variable wavelength detector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001412,cytometric bead array assay measuring epitope specific RANTES production by T cells,CCL5/RANTES release|cytometric bead array,An assay of epitope specific RANTES production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001232,,,,,,,,,,,,,,,,,,,An assay of epitope specific RANTES production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific RANTES production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001412,,,,,,,,,,,,,,,,,,,,,,,,CCL5/RANTES release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific RANTES production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000726,peak matching,,Peak matching is a data transformation performed on a dataset of a graph of ordered data points (e.g. a spectrum) with the objective of pattern matching local maxima above a noise threshold,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,Peak matching is a data transformation performed on a dataset of a graph of ordered data points (e.g. a spectrum) with the objective of pattern matching local maxima above a noise threshold,PERSON: Ryan Brinkman,,,,,,peak matching,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000726,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,peak matching,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Ryan Brinkman|James Malone,,
http://purl.obolibrary.org/obo/OBI_0001821,ELISPOT assay measuring epitope specific interleukin-22 production by T cells,IL-22 release|ELISPOT,An assay of epitope specific interleukin-22 production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001217,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-22 production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific interleukin-22 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001821,,,,,,,,,,,,,,,,,,,,,,,,IL-22 release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific interleukin-22 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/CHEBI_31642,gadodiamide hydrate,,The hydrate of gadodiamide.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,The hydrate of gadodiamide.,,,,,,,gadodiamide hydrate,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:31642,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,gadodiamide hydrate,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001866,secondary cultured cell,,A cultured cell that has been passaged or derives from a cell that has been passaged in culture. |A secondary cultured cell has been passaged in culture or is a descendant of such a cell that is derived through propagation in culture.,false,,,http://purl.obolibrary.org/obo/CL_0000010,,,,,,,,,,,,,,,,,,,A cultured cell that has been passaged or derives from a cell that has been passaged in culture. ,PERSON: Matthew Brush,,http://purl.obolibrary.org/obo/CL_0000001,,,"The term 'secondary cell culture' is generally used in biological texts/protocols to refer to any culture following an initial passage.  We include it here because there are often a number of passages between a primary culture and the establishment of a stable, homogenous cell line.  Such cultures are considered to be 'secondary cultures' but not 'cell lines' during this intermediate passaging/selection period between their derivation from a 'primary cell culture' and derivation into a 'cell line', which is a more specific type of secondary culture.",secondary cultured cell,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001866,,,,,,,,,,,,,,,,,,A secondary cultured cell has been passaged in culture or is a descendant of such a cell that is derived through propagation in culture.,,,,,,,,,,,,,,,,,,,,,,,,,,,,secondary cultured cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Matthew Brush,,
http://purl.obolibrary.org/obo/BFO_0000002,continuant,,"An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.",false,,,http://purl.obolibrary.org/obo/BFO_0000001,,,,,,,Continuant,continuant,,,,,,,,,,,"An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.",,,,,,"BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240|Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants",continuant,"A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])",,,,,,,,,(forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] |(forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] |(forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] |(forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] ,"if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])|if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])|if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000002,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,continuant,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001654,mass spectrometry assay measuring binding of a B cell epitope:antibody complex,qualitative binding|mass spectrometry,A B cell epitope qualitative binding to antibody assay that uses a mass spectrometry assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001703,,,,,,,,,,,,,,,,,,,A B cell epitope qualitative binding to antibody assay that uses a mass spectrometry assay.,IEDB,,,,,,mass spectrometry assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001654,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|mass spectrometry,,,,,,,,,,,,,,,,,,,,,,mass spectrometry assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/IAO_0000308,figure,,An information content entity consisting of a two dimensional arrangement of information content entities such that the arrangement itself is about something.,false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,,,,,,,,,,,,,,,,An information content entity consisting of a two dimensional arrangement of information content entities such that the arrangement itself is about something.,,,,,,,figure,,"Any picture, diagram or table",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000308,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,figure,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0302835,denatured polymer,,Is a polymer which has lost secondary or tertiary structure,false,,,http://purl.obolibrary.org/obo/OBI_0000047|http://purl.obolibrary.org/obo/CHEBI_33839,,,,,,,,,,,,,,,,,,,Is a polymer which has lost secondary or tertiary structure,http://en.wikipedia.org/wiki/Denaturation_%28biochemistry%29,,,,,,denatured polymer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302835,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,denatured polymer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0000557,flash pump system,,"Any pump system used in flash column chromatography to push the solvent through the column. Better flow rates can be achieved by using a pump or by using compressed gas (e.g. air, nitrogen, or argon) to push the solvent through the column (flash column chromatography).",false,,,http://purl.obolibrary.org/obo/OBI_0000589,,,,,,,,,,,,,,,,,,,"Any pump system used in flash column chromatography to push the solvent through the column. Better flow rates can be achieved by using a pump or by using compressed gas (e.g. air, nitrogen, or argon) to push the solvent through the column (flash column chromatography).",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01048,,,,,,flash pump system,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000557,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,flash pump system,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0200109,b transformation,,"A b transformation is a data transformation obtained by applying the function B described in what follows to a (one dimensional) real number input. B(x)= a*exp(b*x)-c*exp(-d*x)+f, where exp denotes an exponential transformation and a, b, c, d, f are real constants with a, b, c, d positive with the objective of normalization.",false,,,http://purl.obolibrary.org/obo/OBI_0200169,,,,,,,,,,,,,,,,,,,"A b transformation is a data transformation obtained by applying the function B described in what follows to a (one dimensional) real number input. B(x)= a*exp(b*x)-c*exp(-d*x)+f, where exp denotes an exponential transformation and a, b, c, d, f are real constants with a, b, c, d positive with the objective of normalization.",WEB: http://flowcyt.sourceforge.net/gating/latest.pdf,,,,,,b transformation,,This type of transformation is typically used in flow cytometry.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200109,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,b transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Ryan Brinkman|Joseph Spliden|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0002024,SOLiD 4 System,Applied Biosystems SOLiD 4 System|SOLiD 4,"An AB SOLid System which is manufacted by the Applied Biosystems corporation. Built upon SOLiD sequencing technology, the machine generates greater than 1 billion mappable reads per run.",false,,,http://purl.obolibrary.org/obo/OBI_0000696,,,,Applied Biosystems SOLiD 4 System|SOLiD 4,,,,,,,,,,,,,,,"An AB SOLid System which is manufacted by the Applied Biosystems corporation. Built upon SOLiD sequencing technology, the machine generates greater than 1 billion mappable reads per run.",http://www.appliedbiosystems.com/absite/us/en/home/applications-technologies/solid-next-generation-sequencing/next-generation-systems/solid-4-system.html?CID=FL-091411_solid4,,,,,,SOLiD 4 System,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002024,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,SOLiD 4 System,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001537,purified MHC competitive binding assay measuring equilibrium dissociation constant [KD] of a MHC:ligand complex using fluorescence detection,dissociation constant KD|purified MHC/competitive/fluorescence|nM,A purified MHC ligand binding equilibrium dissociation constant (KD) determination assay that uses fluorescence detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation.,false,,,http://purl.obolibrary.org/obo/OBI_0001988|http://purl.obolibrary.org/obo/OBI_0001499,,,,,,,,,,,,,,,,,,,A purified MHC ligand binding equilibrium dissociation constant (KD) determination assay that uses fluorescence detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation.,IEDB,,,,,,purified MHC competitive binding assay measuring equilibrium dissociation constant [KD] of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001537,,,,,,,,,,,,,,,,,,,,,,,,dissociation constant KD|purified MHC/competitive/fluorescence|nM,,,,,,,,,,,,,,,,,,,,,,purified MHC competitive binding assay measuring equilibrium dissociation constant [KD] of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/IAO_0000314,document part,,an information content entity that is part of a document,false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,,,,,,,,,,,,,,,,an information content entity that is part of a document,,,,,,,document part,,"An abstract, introduction, method or results section.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000310,IAO:0000314,http://purl.obolibrary.org/obo/IAO_0000310,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,document part,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0302908,document editing,,is a planned process with specified input original document and specified output edited document,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,,,is a planned process with specified input original document and specified output edited document,adapted from wikipedia,,,,,,document editing,,"Wax DB, Beilin Y, Hossain S, Lin HM, Reich DL.
Manual editing of automatically recorded data in an anesthesia information management system. Anesthesiology. 2008 Nov;109(5):811-5. PMID: 18946292",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000310,http://purl.obolibrary.org/obo/OBI_0302874,,,OBI:0302908,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,document editing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra and OBI consortium,,
http://purl.obolibrary.org/obo/OBI_0001893,organization of specimen collector,Specimen Collector's Institution,An organization that is the affiliation of the person collecting the specimen,false,,,http://purl.obolibrary.org/obo/OBI_0000245,,,,,,,,,,,,,,,,,,,An organization that is the affiliation of the person collecting the specimen,NIAID GSCID-BRC metadata working group,,,,,,organization of specimen collector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001893,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,organization of specimen collector,,,,,,Specimen Collector's Institution,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0200181,center calculation data transformation,,A center calculation data transformation is a data transformation that has objective of center calculation.,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,A center calculation data transformation is a data transformation that has objective of center calculation.,PERSON: James Malone,,,,,,center calculation data transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200181,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,center calculation data transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0001447,epitope specific macrophage inflammatory protein-1 gamma production by T cells,,A process of macrophage inflammatory protein-1 gamma production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0071607|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of macrophage inflammatory protein-1 gamma production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific macrophage inflammatory protein-1 gamma production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001447,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific macrophage inflammatory protein-1 gamma production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000858,record of unknown sex,,a record indicating that the biological sex of an organism is not known.,false,,,http://purl.obolibrary.org/obo/OBI_0000852,,,,,,,,,,,,,,,,,,,a record indicating that the biological sex of an organism is not known.,,,,,,I think the statement is still about the instance of the biological sex quality of an organism. It is also about information available to the person making the statement.,record of unknown sex,,A database record indicating that the tissue sample in a microarray experiment came from an organism for which the biological sex is not known to the person who created the record.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000858,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/PATO_0000047,,,,,,,,,,,,,,,,record of unknown sex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000651,urine specimen,,a portion of urine collected from an organism,false,,,http://purl.obolibrary.org/obo/OBI_0001479,,,,,,,,,,,,,,,,,,,a portion of urine collected from an organism,,,http://purl.obolibrary.org/obo/UBERON_0001088,,,"This could be instead a kind of collection of secreted stuff. Among secreted stuff there is passive, and active. urine is secreted, passiv.  lavage is secreted, active|4/10/2011BP: It seems to me that the editor notes refer to a previous version, and are no longer relevant. |are we happy calling collection of urine a material separation?",urine specimen,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000112,,,,,,,,,,,,OBI:0000651,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0600005,,,urine specimen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001548,equilibrium association constant (KA),,A binding constant defined as the ratio of koff over kon (off-rate of binding divided by on-rate),false,,,http://purl.obolibrary.org/obo/OBI_0001144,,,,,,,,,,,,,,,,,,,A binding constant defined as the ratio of koff over kon (off-rate of binding divided by on-rate),IEDB,,,,,,equilibrium association constant (KA),,KA = 10^-12 M^-1 is the equilibirum association constant maximally found for antibody binding to haptens. ,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001548,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,equilibrium association constant (KA),,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Bjoern Peters, Randi Vita",,
http://purl.obolibrary.org/obo/OBI_0600050,specific enzymatic cleavage,,a protocol application to digest the fraction of input material that is susceptible to that enzyme,false,,,http://purl.obolibrary.org/obo/OBI_0000231,,,,,,,,,,,,,,,,,,,a protocol application to digest the fraction of input material that is susceptible to that enzyme,OBI branch derived,,,,,,specific enzymatic cleavage,,The use of a protease to digest a protein into peptides,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600050,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,specific enzymatic cleavage,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Kevin Clancy,,
http://purl.obolibrary.org/obo/OBI_0001095,coagulation analyzer,,A device for automatically analyzing blood coagulation in a clinical laboratory.,false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,A device for automatically analyzing blood coagulation in a clinical laboratory.,United States Patent 5439646,,,,,,coagulation analyzer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001095,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,coagulation analyzer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/UBERON_0002107,liver,,"An exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO].",false,,,http://purl.obolibrary.org/obo/CARO_0000055,,,,,,,,,,,,,,,,,,,"An exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO].",,,,,,,liver,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UBERON:0002107,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uberon.owl,,,,,,,,,,,,,,,,,,,liver,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/UBERON_0002106,spleen,,the organ that functions to filter blood and to store red corpuscles and platelets,false,,,http://purl.obolibrary.org/obo/CARO_0001008,,,,,,,,,,,,,,,,,,,the organ that functions to filter blood and to store red corpuscles and platelets,,,,,,,spleen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UBERON:0002106,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uberon.owl,,,,,,,,,,,,,,,,,,,spleen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001807,cytometric bead array assay measuring epitope specific interleukin-3 production by T cells,IL-3 release|cytometric bead array,An assay of epitope specific interleukin-3 production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001406,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-3 production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific interleukin-3 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001807,,,,,,,,,,,,,,,,,,,,,,,,IL-3 release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific interleukin-3 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0002018,transcription factor binding site identification by ChIP-chip assay,TF Binding ChIP-chip,A ChIP-chip assay to identify binding sites for transcription factors.,false,,,http://purl.obolibrary.org/obo/OBI_0001248|http://purl.obolibrary.org/obo/OBI_0000291,,http://purl.obolibrary.org/obo/OBI_0001398,,TF Binding ChIP-chip,,,,,,,,,,,,,,,A ChIP-chip assay to identify binding sites for transcription factors.,Penn group,,,,,,transcription factor binding site identification by ChIP-chip assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002018,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,transcription factor binding site identification by ChIP-chip assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Beta Cell Biology Consoritum,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/IAO_0000442,author role,,"A role inhering in a person or organization that is realized when the bearer participates in the work which is the basis of the document, in the writing of the document, and signs it with their name.",false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,,,"A role inhering in a person or organization that is realized when the bearer participates in the work which is the basis of the document, in the writing of the document, and signs it with their name.",,,,,,,author role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000442,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,author role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot|PERSON: Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0001983,tolerance induction intervention experiment,,An in vivo intervention experiment that tests the ability of the intervention to decrease an immune response.,false,,,http://purl.obolibrary.org/obo/OBI_0001980,,,,,,,,,,,,,,,,,,,An in vivo intervention experiment that tests the ability of the intervention to decrease an immune response.,IEDB,,,,,should have tolerance induction as intervention,tolerance induction intervention experiment,,Injecting a set of mice with a Der p 2 peptide and measuring the IL-2 response of T cells from those mice when exposed to the Der p 2 protein in vitro to determine if those T cells made less IL-2 than cells taken from mice which were not injected with the same Der p 2 peptide.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001983,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,tolerance induction intervention experiment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001826,ELISPOT assay measuring epitope specific interleukin-21 production by T cells,IL-21 release|ELISPOT,An assay of epitope specific interleukin-21 production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001237,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-21 production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific interleukin-21 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001826,,,,,,,,,,,,,,,,,,,,,,,,IL-21 release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific interleukin-21 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001138,X-ray source,x-ray generator,A device that is used to generate X-rays.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,x-ray generator,,,,,,,,,,,,,,,A device that is used to generate X-rays.,http://en.wikipedia.org/wiki/X-ray_generator,,,,,,X-ray source,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000374,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001138,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,X-ray source,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0400036,FACS Calibur,,The FACS Calibur is one of the most popular cytometers in use for research.,false,,,http://purl.obolibrary.org/obo/OBI_0400099,,,,,,,,,,,,,,,,,,,The FACS Calibur is one of the most popular cytometers in use for research.,"""http://www.bdbiosciences.com/immunocytometry_systems/products/display_product.php?keyID=45, 2007-05-11""",,,,,,FACS Calibur,,"""FACS Calibur at TFL, BCCRC, Vancouver""",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400036,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,FACS Calibur,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0400117,vacuum dryer,,"An instrument which removes liquid by the application of negative pressure,  i.e. vacuum.",false,,,http://purl.obolibrary.org/obo/OBI_0000967|http://purl.obolibrary.org/obo/OBI_0001034,,,,,,,,,,,,,,,,,,,"An instrument which removes liquid by the application of negative pressure,  i.e. vacuum.",MO,,,,,,vacuum dryer,,Model 777 Microarray Oven,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/OBI_0000370|http://purl.obolibrary.org/obo/OBI_0000383|http://purl.obolibrary.org/obo/OBI_0000401,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400117,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,vacuum dryer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Trish Whetzel,,
http://purl.obolibrary.org/obo/OBI_0000163,radiolabel role,radiolabel,a molecular label role which inheres in a material entity which is realized by the process of radioactivity detection,false,,,http://purl.obolibrary.org/obo/REO_0000171,,,,radiolabel,,,,,,,,,,,,,,,a molecular label role which inheres in a material entity which is realized by the process of radioactivity detection,,,,,,,radiolabel role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000163,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,radiolabel role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0100016,blood plasma specimen,plasma,"a material entity which corresponds to the liquid component of blood, in which the blood cells are suspended.",false,,,http://purl.obolibrary.org/obo/OBI_0000953|http://purl.obolibrary.org/obo/BFO_0000040,,,,plasma,,,,,,,,,,,,,,,"a material entity which corresponds to the liquid component of blood, in which the blood cells are suspended.",WEB: http://en.wikipedia.org/wiki/Blood_plasma,,,,,"03/21/2010: BP, blood plasma is defined as the output of certain separation processes, so this is in the domain of OBI, not FMA.",blood plasma specimen,,PMID: 18217225.Sex Transm Dis. 2008 Jan;35(1):55-60. Review.Human immunodeficiency virus viral load in blood plasma and semen: review and implications of empirical findings.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0100016,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,blood plasma specimen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot|PERSON: Maura Gasparetto|PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000988,performing a diagnosis,,The interpretation of the information available about bodily features (clinical picture) of a patient resulting in a diagnosis,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,The interpretation of the information available about bodily features (clinical picture) of a patient resulting in a diagnosis,,,,,,,performing a diagnosis,,"Diagnosing that a patient has pneumonia based on information on measurements of temperature, sound of breathing, and patient complaining about a headache.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000075,,,OBI:0000988,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,performing a diagnosis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/IDO_0000586,infection,,"A part of an extended organism that itself has as part a population of one or more infectious agents and that (1) exists as a result of processes initiated by members of the infectious agent population and is (2) clinically abnormal in virtue of the presence of this infectious agent population, or (3) has a disposition to bring clinical abnormality to immunocompetent organisms of the same Species as the host (the organism corresponding to the extended organism) through transmission of a member or offspring of a member of the infectious agent population.",false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,"A part of an extended organism that itself has as part a population of one or more infectious agents and that (1) exists as a result of processes initiated by members of the infectious agent population and is (2) clinically abnormal in virtue of the presence of this infectious agent population, or (3) has a disposition to bring clinical abnormality to immunocompetent organisms of the same Species as the host (the organism corresponding to the extended organism) through transmission of a member or offspring of a member of the infectious agent population.",,,,,,,infection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IDO:0000586,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ido.owl,,,,,,,,,,,,,,,,,,,infection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/IAO_0000576,obsolete_establishing a CRID registry,,"a planned process with the objective to establish a system that allows to refer to specific entities of a certain kind and store information about them, by establishing a CRID registry and plan specifications for the process of 1) assigning a CRID and 2) looking up a CRID.",true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,"a planned process with the objective to establish a system that allows to refer to specific entities of a certain kind and store information about them, by establishing a CRID registry and plan specifications for the process of 1) assigning a CRID and 2) looking up a CRID.",,,,,,"MC, 20101124: deprecated following discussion at IAO call 20101124. Term was deemed not necessary - no use case for now.",obsolete_establishing a CRID registry,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,IAO:0000576,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_establishing a CRID registry,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200183,scaling objective,,"is a data transformation objective where all, or some of a data set is adjusted by some data transformation according to some scale, for example a user defined minimum or maximum",false,,,http://purl.obolibrary.org/obo/OBI_0200166,,,,,,,,,,,,,,,,,,,"is a data transformation objective where all, or some of a data set is adjusted by some data transformation according to some scale, for example a user defined minimum or maximum",,,,,,Awaiting English definition from Monnie McGee,scaling objective,,Scaling gene expression data for cross platform analysis http://www.springerprotocols.com/Abstract/doi/10.1007/978-1-59745-454-4_13,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200183,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,scaling objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Person:Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0500019,self vs self design,,"A study design that investigates variance and error estimates in the experimental system, and is where the same extract is compared.",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A study design that investigates variance and error estimates in the experimental system, and is where the same extract is compared.",MO_490,,,,,,self vs self design,,"PMID: 17411393-Dye-specific bias effects, commonly observed in the two-color microarray platform, are normally corrected using the dye swap design. This design, however, is relatively expensive and labor-intensive. We propose a self-self hybridization design as an alternative to the dye swap design. In this design, the treated and control samples are labeled with Cy5 and Cy3 (or Cy3 and Cy5), respectively, without dye swap, along with a set of self-self hybridizations on the control sample. We compare this design with the dye swap design through investigation of mouse primary hepatocytes treated with three peroxisome proliferator-activated receptor-alpha (PPARalpha) agonists at three dose levels. Using Agilent's Whole Mouse Genome microarray, differentially expressed genes (DEG) were determined for both the self-self hybridization and dye swap designs. The DEG concordance between the two designs was over 80% across each dose treatment and chemical. Furthermore, 90% of DEG-associated biological pathways were in common between the designs, indicating that biological interpretations would be consistent. The reduced labor and expense for the self-self hybridization design make it an efficient substitute for the dye swap design. For example, in larger toxicogenomic studies, only about half the chips are required for the self-self hybridization design compared to that needed in the dye swap design.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500019,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,self vs self design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra on behalf of MO,,
http://purl.obolibrary.org/obo/OBI_0000043,xenotransplantation,,"is the transplantation of living cells, tissues or \norgans from one species to another such as from pigs to humans",false,,,http://purl.obolibrary.org/obo/OBI_0000105,,,,,,,,,,,,,,,,,,,"is the transplantation of living cells, tissues or \norgans from one species to another such as from pigs to humans",OBI branch derived,,,,,,xenotransplantation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000043,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,xenotransplantation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0001834,drawing a conclusion,,A planned process in which new information is inferred from existing information.,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,,,A planned process in which new information is inferred from existing information.,,,,,,,drawing a conclusion,,"Concluding that the length of the hypotenuse is equal to the square root of the sum of squares of the other two sides in a right-triangle. 
Concluding that a gene is upregulated in a tissue sample based on the band intensity in a western blot.  Concluding that a patient has a infection based on measurement of an elevated body temperature and reported headache. Concluding that there were problems in an investigation because data from PCR and microarray are conflicting. 
",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,OBI:0001834,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,drawing a conclusion,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001091,mechanical balance,,"A balance that is used to compare the weights of two bodies, to determine the difference in mass (or weight).",false,,,http://purl.obolibrary.org/obo/OBI_0001135,,,,,,,,,,,,,,,,,,,"A balance that is used to compare the weights of two bodies, to determine the difference in mass (or weight).",http://www.britannica.com/EBchecked/topic/49765/balance,,,,,,mechanical balance,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001091,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,mechanical balance,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0000855,total RNA extraction,,A RNA extraction process in which total cellular and organelle RNA are extracted.|,false,,,http://purl.obolibrary.org/obo/OBI_0666666,,,,,,,,,,,,,,,,,,,A RNA extraction process in which total cellular and organelle RNA are extracted.,UPenn Group,,,,,,total RNA extraction,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000855,,,,,,,,,,,,,,,,,,"",,,,,,,,,,,,,,,,,,,,,,,,,,,,total RNA extraction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jie Zheng|Person: Chris Stoeckert,,
http://purl.obolibrary.org/obo/IAO_0000400,cartesian spatial coordinate datum,,"A cartesian spatial coordinate datum is a representation of a point in a spatial region, in which equal changes in the magnitude of a coordinate value denote length qualities with the same magnitude",false,,,http://purl.obolibrary.org/obo/IAO_0000027,,,,,,,,,,,,,,,,,AR notes: We need to discuss whether it should include site.,,"A cartesian spatial coordinate datum is a representation of a point in a spatial region, in which equal changes in the magnitude of a coordinate value denote length qualities with the same magnitude",,http://purl.obolibrary.org/obo/BFO_0000018,,,,2009-08-18 Alan Ruttenberg - question to BFO list about whether the BFO sense of the lower dimensional regions is that they are always part of actual space (the three dimensional sort) http://groups.google.com/group/bfo-discuss/browse_thread/thread/9d04e717e39fb617,cartesian spatial coordinate datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000400,,,,,,,,,,,,,,,,,,,,http://groups.google.com/group/bfo-discuss/browse_thread/thread/9d04e717e39fb617,,,,,,,,,,,,,,,,,,,,,,,,,,cartesian spatial coordinate datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0001186,epitope protection from infectious challenge experiment based on pathogen burden ,pathogen burden after infectious challenge ,An epitope protection from infectious challenge experiment in which the readout is a reduction in the presence of pathogens in the host compared to controls. ,false,,,http://purl.obolibrary.org/obo/OBI_0001179,,,,,,,,,,,,,,,,,,,An epitope protection from infectious challenge experiment in which the readout is a reduction in the presence of pathogens in the host compared to controls. ,,,,,,,epitope protection from infectious challenge experiment based on pathogen burden ,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001187,,,,,,,,,,,,,,,,OBI:0001186,,,,,,,,,,,,,,,,,,,,,,,,pathogen burden after infectious challenge ,,,,,,,,,,,,,,,,,,,,,,epitope protection from infectious challenge experiment based on pathogen burden ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001832,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-17F production by T cells,IL-17F release|RNA/DNA detection,A T cell epitope specific interleukin-17F production assay that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001291|http://purl.obolibrary.org/obo/OBI_0001772,,,,,,,,,,,,,,,,,,,A T cell epitope specific interleukin-17F production assay that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-17F production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001832,,,,,,,,,,,,,,,,,,,,,,,,IL-17F release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-17F production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/IAO_0000306,table,,"A textual entity that contains a two-dimensional arrangement of texts repeated at regular intervals across a spatial range, such that the spatial relationships among the constituent texts expresses propositions",false,,,http://purl.obolibrary.org/obo/IAO_0000300,,,,,,,,,,,,,,,,,,,"A textual entity that contains a two-dimensional arrangement of texts repeated at regular intervals across a spatial range, such that the spatial relationships among the constituent texts expresses propositions",,,,,,,table,,"| T     F
--+-----
T   | T     F
F   |  F    F",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000306,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,table,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0001793,cytometric bead array assay measuring epitope specific lymphotoxin A production by T cells,lymphotoxin A/TNFb release|cytometric bead array,An assay of epitope specific lymphotoxin A production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001327|http://purl.obolibrary.org/obo/OBI_0001368,,,,,,,,,,,,,,,,,,,An assay of epitope specific lymphotoxin A production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific lymphotoxin A production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001793,,,,,,,,,,,,,,,,,,,,,,,,lymphotoxin A/TNFb release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific lymphotoxin A production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001640,biological activity assay measuring epitope specific immunoglobulin-mediated antigen activation,antigen activation|biological activity,A B cell epitope dependent biological activity determination assay that detects antigen activation.,false,,,http://purl.obolibrary.org/obo/OBI_0001706,,,,,,,,,,,,,,,,,,,A B cell epitope dependent biological activity determination assay that detects antigen activation.,IEDB,,,,,,biological activity assay measuring epitope specific immunoglobulin-mediated antigen activation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001640,,,,,,,,,,,,,,,,,,,,,,,,antigen activation|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific immunoglobulin-mediated antigen activation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000620,Bruker micro imaging probe,,"For medical, biological and material sciences research, avance imaging systems provide optimal object handling and performance with a variety of samples types. Two classes of imaging probes are available: in vivo probes for handling and sustaining live objects such as animals and plants, and conventional imaging probes for materials samples.",false,,,http://purl.obolibrary.org/obo/OBI_0000561,,,,,,,,,,,,,,,,,NMR probe,,"For medical, biological and material sciences research, avance imaging systems provide optimal object handling and performance with a variety of samples types. Two classes of imaging probes are available: in vivo probes for handling and sustaining live objects such as animals and plants, and conventional imaging probes for materials samples.",WEB:<http://www.bruker-biospin.com/probes_microimaging.html>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400225,,,,,,Bruker micro imaging probe,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000620,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker micro imaging probe,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000021,list-mode data file,,"A list-mode data file is a binary digital entity where events are stored sequentially, parameter by parameter.",false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,,,,,,,,,,,,,,,,"A list-mode data file is a binary digital entity where events are stored sequentially, parameter by parameter.",group:Flow Cytometry community,,,,,"One example of usage is in the context of flow cytometry, however is not restricted to this community and is more widely used, e.g. by imaging people.",list-mode data file,,An example of a list-mode data file is a file following list-mode Flow Cytometry Standard (FCS) format. Since FCS files can be in histogram mode or  list-mode we have to specify which data format specifically. List-mode format in the overwhelming (even universal) option used.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000021,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,list-mode data file,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0000803,denaturing,,Is a process in which the tertiary or secondary structure of a polymer is disrupted,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,Is a process in which the tertiary or secondary structure of a polymer is disrupted,http://en.wikipedia.org/wiki/Denaturation_%28biochemistry%29,,,,,,denaturing,,Denaturing DNA in alcohol,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000803,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,denaturing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/CHEBI_37973,phosphorus-33 atom,,"The radioactive isotope of phosphorus with relative atomic mass 32.971725, half-life of 25.34 days and nuclear spin (1)/2.",false,,,http://purl.obolibrary.org/obo/CHEBI_33250,,,,,,,,,,,,,,,,,,,"The radioactive isotope of phosphorus with relative atomic mass 32.971725, half-life of 25.34 days and nuclear spin (1)/2.",,,,,,,phosphorus-33 atom,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/REO_0000171,,,,,,,,,,,,CHEBI:37973,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,phosphorus-33 atom,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0600032,artificially induced DNA repair,,a protocol application to repair damaged DNA molecules,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,---\nis this really a protocol?\n--> This as several other protocol applications is also a natural process. The fact that it is induced experimetnally by following a protocol makes it a protocol application. Need to make sure that labels don't conflict wi,,a protocol application to repair damaged DNA molecules,OBI branch derived,,,,,,artificially induced DNA repair,,the use of DNA repair enzymes uracil DNA glycosylase and 3-methyladenine DNA glycosylase to repair DNA strands,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600032,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,artificially induced DNA repair,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/BFO_0000031,generically dependent continuant,,A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time.|b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001]),false,,,http://purl.obolibrary.org/obo/BFO_0000002,,,,,,,GenericallyDependentContinuant,gdc,,,,,,,,,,,A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time.|b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001]),,,,,,,generically dependent continuant,,"the pdf file on your laptop, the pdf file that is a copy thereof on my laptop|the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule.|The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity.",,,,,,,,(iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000031,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,generically dependent continuant,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001783,intracellular cytokine staining assay measuring epitope specific monocyte chemotactic protein-1 production by T cells,CCL2/MCP-1 release|ICS,An assay of epitope specific monocyte chemotactic protein-1 production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001465,,,,,,,,,,,,,,,,,,,An assay of epitope specific monocyte chemotactic protein-1 production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific monocyte chemotactic protein-1 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001783,,,,,,,,,,,,,,,,,,,,,,,,CCL2/MCP-1 release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific monocyte chemotactic protein-1 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000843,Sysmex CA-6000 Coagulation Analyzer,,The Sysmex CA-6000 automated coagulation analyzer is a random access instrument that is capable of performing 20 clot-based and chromogenic assays,false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,,The Sysmex CA-6000 automated coagulation analyzer is a random access instrument that is capable of performing 20 clot-based and chromogenic assays,web:http://www.clinchem.org/cgi/content/full/43/9/1783@2009/08/06,,,,,,Sysmex CA-6000 Coagulation Analyzer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000843,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Sysmex CA-6000 Coagulation Analyzer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0000555,autosampler,,An optional part of an NMR instrument used to hold samples prior to NMR analysis and that sequentially loads these samples into the analytical part of the NMR instrument. \n   alt The autosampler is an automatic sample changer device.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,NMR instrument,,An optional part of an NMR instrument used to hold samples prior to NMR analysis and that sequentially loads these samples into the analytical part of the NMR instrument. \n   alt The autosampler is an automatic sample changer device.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400002,,,,,,autosampler,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000555,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,autosampler,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001226,environmental history design,,"A study design in which some aspect of the organism's environmental history is studied, such as exposure to teratogen, radiation, climate etc.",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A study design in which some aspect of the organism's environmental history is studied, such as exposure to teratogen, radiation, climate etc.",MO_698 environmental_history_design,,,,,,environmental history design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000015,,,,,,,,,,,,,,,,OBI:0001226,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,environmental history design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0200165,quantile proportion of false positives correction method,QPFP correction method,A quantile proportion of false positives correction method is a multiple testing procedure that controls the pth quantile of the distribution of the proportion of false positives among the rejected hypothesis (false discovery rate).,false,,,http://purl.obolibrary.org/obo/OBI_0200089,,,,QPFP correction method,,,,,,,,,,,,,,,A quantile proportion of false positives correction method is a multiple testing procedure that controls the pth quantile of the distribution of the proportion of false positives among the rejected hypothesis (false discovery rate).,"Dudoit, Sandrine and van der Laan, Mark J. (2008) Multiple Testing Procedures with Applications to Genomics.  New York: Springer , p. 21",,,,,,quantile proportion of false positives correction method,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200165,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,quantile proportion of false positives correction method,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Monnie McGee,,
http://purl.obolibrary.org/obo/OBI_0000119,number of particles in subset,,A measurement datum measuring the number of subjects in a defined subset in a flow cytometer instrument. The datum has a qualitative role,false,,,http://purl.obolibrary.org/obo/IAO_0000109,,,,,,,,,,,,,,,,,,,A measurement datum measuring the number of subjects in a defined subset in a flow cytometer instrument. The datum has a qualitative role,Submitted by the Flow Cytometry community in DigitalEntity-FlowCytometry-2007-03-30.txt,,,,,,number of particles in subset,,"500, 200, 0",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000119,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,number of particles in subset,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Kevin Clancy,,
http://purl.obolibrary.org/obo/OBI_0000943,chemical cleavage,,chemical cleavage is a protocol application relying on a chemical compound to cause the fragmentation of an input material that is susceptible to that chemical agent,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,chemical cleavage is a protocol application relying on a chemical compound to cause the fragmentation of an input material that is susceptible to that chemical agent,RNA ontology group,,,,,,chemical cleavage,,"PMID: 20171258. Comparative reactivity of mismatched and unpaired bases in relation to their type and surroundings. Chemical cleavage of DNA mismatches in mutation detection analysis.Yakubovskaya MG, Belyakova AA, Gasanova VK, Belitsky GA, Dolinnaya NG.
Biochimie. 2010 Feb 18.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100051,,,,OBI:0000943,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,chemical cleavage,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000361,ion source,,"An ion source is a device that is part of a mass
spectrometer that ionizes the material under analysis. The ions are
then transported by magnetic or electric fields to the mass analyzer.
Techniques for ionization have been key to determining what types of
samples can be analyzed by mass spectrometry. Electron ionization and
chemical ionization are used for gases and vapors. In chemical
ionization sources, the material is ionized by chemical ion-molecule
reactions during collisions in the source. Two techniques often used
with liquid and solid biological samples include electrospray
ionization (due to John Fenn PMID 2675315.) and matrix-assisted laser
desorption/ionization (MALDI, due to M. Karas and F. Hillenkamp
(Measuring Mass: From Positive Rays to Proteins by Michael A. Grayson
(Editor) (ISBN 0-941901-31-9))).",false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,"An ion source is a device that is part of a mass
spectrometer that ionizes the material under analysis. The ions are
then transported by magnetic or electric fields to the mass analyzer.
Techniques for ionization have been key to determining what types of
samples can be analyzed by mass spectrometry. Electron ionization and
chemical ionization are used for gases and vapors. In chemical
ionization sources, the material is ionized by chemical ion-molecule
reactions during collisions in the source. Two techniques often used
with liquid and solid biological samples include electrospray
ionization (due to John Fenn PMID 2675315.) and matrix-assisted laser
desorption/ionization (MALDI, due to M. Karas and F. Hillenkamp
(Measuring Mass: From Positive Rays to Proteins by Michael A. Grayson
(Editor) (ISBN 0-941901-31-9))).",http://en.wikipedia.org/wiki/Mass_spectrometry#Ion_source,,,,,,ion source,,The ion source of a Voyager-DE??? STR Biospectrometry Workstation,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/OBI_0000385,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000361,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ion source,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Frank Gibson,,
http://purl.obolibrary.org/obo/OBI_0001959,sequencing library multiplexing,,"a planned process which consists in running a set of samples as a pool in one single instrument run of data acquisition process while retaining the ability to associate individual results to each of the individual input samples thanks to the use of a multiplex identifier, introduced during the ligation step of the individual library preparation and specific to a given sample.",false,,,http://purl.obolibrary.org/obo/OBI_0000094,,,,,,,,,,,,,,,,,,,"a planned process which consists in running a set of samples as a pool in one single instrument run of data acquisition process while retaining the ability to associate individual results to each of the individual input samples thanks to the use of a multiplex identifier, introduced during the ligation step of the individual library preparation and specific to a given sample.",OBI,,,,,,sequencing library multiplexing,,http://www.illumina.com/technology/multiplexing_sequencing_assay.ilmn,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001959,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sequencing library multiplexing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001754,cytometric bead array assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells,CXCL9/MIG release|cytometric bead array,An assay of epitope specific chemokine (C-X-C motif) ligand 9 production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001459,,,,,,,,,,,,,,,,,,,An assay of epitope specific chemokine (C-X-C motif) ligand 9 production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001754,,,,,,,,,,,,,,,,,,,,,,,,CXCL9/MIG release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001786,ELISPOT assay measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells,CCL9/MIP-1g release|ELISPOT,An assay of epitope specific macrophage inflammatory protein-1 gamma production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001456,,,,,,,,,,,,,,,,,,,An assay of epitope specific macrophage inflammatory protein-1 gamma production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001786,,,,,,,,,,,,,,,,,,,,,,,,CCL9/MIP-1g release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000281,intraperitoneal injection,,is the injection of a material entity (bearing the administered substance role) into the peritoneum (bearing the target role) of an organism using a syringe,false,,,http://purl.obolibrary.org/obo/OBI_0000426|http://purl.obolibrary.org/obo/OBI_0000429,,http://purl.obolibrary.org/obo/OBI_0000434,,,,,,,,,,,,,,,,,is the injection of a material entity (bearing the administered substance role) into the peritoneum (bearing the target role) of an organism using a syringe,,,,,,,intraperitoneal injection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000281,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,intraperitoneal injection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BP,,
http://purl.obolibrary.org/obo/OBI_0001643,biological activity assay measuring epitope specific immunoglobulin-mediated neutralization,neutralization |biological activity,A B cell epitope dependent biological activity determination assay that detects neutralization of the antigen.,false,,,http://purl.obolibrary.org/obo/OBI_0001706,,,,,,,,,,,,,,,,,,,A B cell epitope dependent biological activity determination assay that detects neutralization of the antigen.,IEDB,,,,,,biological activity assay measuring epitope specific immunoglobulin-mediated neutralization,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001643,,,,,,,,,,,,,,,,,,,,,,,,neutralization |biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific immunoglobulin-mediated neutralization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001111,paraffin oven,,A device that is used for the warming of paraffin embedding medium.,false,,,http://purl.obolibrary.org/obo/OBI_0000967|http://purl.obolibrary.org/obo/OBI_0001034,,,,,,,,,,,,,,,,,,,A device that is used for the warming of paraffin embedding medium.,PERSON: Erik Segerdell,,,,,,paraffin oven,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000370|http://purl.obolibrary.org/obo/OBI_0000379|http://purl.obolibrary.org/obo/OBI_0000371,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001111,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,paraffin oven,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/IAO_0000225,obsolescence reason specification,,The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value.,false,,,http://purl.obolibrary.org/obo/IAO_0000102,,,,,,,,,,,,,,,,,,,The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value.,,,,,,"The creation of this class has been inspired in part by Werner Ceusters' paper, Applying evolutionary terminology auditing to the Gene Ontology.",obsolescence reason specification,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000225,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolescence reason specification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot|PERSON: Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0400056,Influx Cell Sorter,,"A Influx Cell Sorter is a flow_cytometer_sorter manufactured by Cytopeia. It is a digital machine, with these laser options: Coherent 70, 90, 300 series water cooled lasers, solid state UV 355nm, Violet 408nm, Violet-Blue 479nm, Blue-488nm, Green-531nm, Red-635nm, Red-647nm. The sorting is multi-way, index, and proportional sorting. Filters and PMTs are used for all parameters (including forward light scatter), and up to 12 PMTs can be included. The Influx cell sorter can be used to measure, sort, and collect ndividual cells.",false,,,http://purl.obolibrary.org/obo/OBI_0400099,,,,,,,,,,,,,,,,,,,"A Influx Cell Sorter is a flow_cytometer_sorter manufactured by Cytopeia. It is a digital machine, with these laser options: Coherent 70, 90, 300 series water cooled lasers, solid state UV 355nm, Violet 408nm, Violet-Blue 479nm, Blue-488nm, Green-531nm, Red-635nm, Red-647nm. The sorting is multi-way, index, and proportional sorting. Filters and PMTs are used for all parameters (including forward light scatter), and up to 12 PMTs can be included. The Influx cell sorter can be used to measure, sort, and collect ndividual cells.",http://www.cytopeia.com/sorter.htm,,,,,,Influx Cell Sorter,,Influx Cell Sorter at TSRI Flow Cytometry Core Facility,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400056,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Influx Cell Sorter,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0001463,transcription profiling by array assay,RNA profiling by array assay,An assay in which  the transcriptome of a biological sample is analysed using array technology.,false,,,http://purl.obolibrary.org/obo/OBI_0000424,,http://purl.obolibrary.org/obo/OBI_0001331,,RNA profiling by array assay,,,,,,,,,,,,,,,An assay in which  the transcriptome of a biological sample is analysed using array technology.,EFO_0002768: transcription profiling by array,,,,,"JZ: add alternative term: 'RNA profiling by array assay' requested by ENCODE developer.
See tracker: https://sourceforge.net/p/obi/obi-terms/757/",transcription profiling by array assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0400148,,,,,,,,,,,,,,,OBI:0001463,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,transcription profiling by array assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: James Malone,,
http://purl.obolibrary.org/obo/OBI_0302897,asphyxiation,,"asphyxiation is a process by which oxygen supplies are restricted (by mechanical, e.g obstructing airways or chemical means, e.g. increasing CO2 partial pressure) resulting in termination of life in oxygen reliant organisms.",false,,,http://purl.obolibrary.org/obo/OBI_0000919,,,,,,,,,,,,,,,,,,,"asphyxiation is a process by which oxygen supplies are restricted (by mechanical, e.g obstructing airways or chemical means, e.g. increasing CO2 partial pressure) resulting in termination of life in oxygen reliant organisms.",OBI branch,,,,,,asphyxiation,,"PMID: 18246869. Loss of cortical function in mice after decapitation, cervical dislocation, potassium chloride injection, and CO2 inhalation. Comp Med. 2007 Dec;57(6):570-",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302897,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,asphyxiation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001945,scaffold N50,,N50 statistic computed for the scaffold produced by the assembly process. The method for computing the value is similar to that of contig N50 but uses scaffold information instead of contig information,false,,,http://purl.obolibrary.org/obo/OBI_0001940,,,,,,,,,,,,,,,,,,,N50 statistic computed for the scaffold produced by the assembly process. The method for computing the value is similar to that of contig N50 but uses scaffold information instead of contig information,adapted from: nature:http://www.nature.com/nrg/journal/v13/n5/box/nrg3174_BX1.html,,,,,,scaffold N50,,"Gigascience. 2012 Dec 27;1(1):18. doi: 10.1186/2047-217X-1-18.
PMID: 23587118. 

""Here, the contig and scaffold N50 of the YH genome were ~20.9 kbp and ~22 Mbp""",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001945,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,scaffold N50,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Alejandra Gonzalez-Beltran|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001725,B cell epitope specific histamine secretion mediated by immunoglobulin,,histamine secretion mediated by immunoglobulin resulting from antibody binding to epitope,false,,,http://purl.obolibrary.org/obo/GO_0097280,,,,,,,,,,,,,,,,,Date: 2012-05-03; Spreadsheet: BcellAssays.xls; Worksheet: Especific template; Mapping: ebcell_specific_mappings.owl,,histamine secretion mediated by immunoglobulin resulting from antibody binding to epitope,IEDB (QTT),,,,,,B cell epitope specific histamine secretion mediated by immunoglobulin,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001725,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,B cell epitope specific histamine secretion mediated by immunoglobulin,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0100066,organ section,,A processed material which derives from an organ and results from a process of dissection or histological sample preparation a portion(formerly an organ section is portion of an organ removed from the context of the organ),false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,,,,,,,,,,,,,,,,A processed material which derives from an organ and results from a process of dissection or histological sample preparation a portion(formerly an organ section is portion of an organ removed from the context of the organ),GROUP: CEBS|GROUP: OBI Biomaterial Branch,,http://purl.obolibrary.org/obo/CARO_0001008,,,,organ section,,"A liver slice used in a perfusion experiment.
Thyroidectomy during laryngectomy for advanced laryngeal carcinoma--whole organ section study with long-term functional evaluation. Clin Otolaryngol Allied Sci. 1995 Apr;20(2):145-9. PMID: 7634521",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0100066,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,organ section,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Helen Parkinson|PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001368,cytometric bead array assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells,TNF release|cytometric bead array,An assay of epitope specific tumor necrosis factor superfamily cytokine production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001400,,,,,,,,,,,,,,,,,,,An assay of epitope specific tumor necrosis factor superfamily cytokine production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001368,,,,,,,,,,,,,,,,,,,,,,,,TNF release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001822,ELISPOT assay measuring epitope specific interleukin-23 production by T cells,IL-23 release|ELISPOT,An assay of epitope specific interleukin-23 production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001363,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-23 production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific interleukin-23 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001822,,,,,,,,,,,,,,,,,,,,,,,,IL-23 release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific interleukin-23 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0002058,biological activity assay measuring epitope specific oncostatin M production by T cells,oncostatin M release|biological activity,A T cell epitope specific cytokine production assay that detects oncostatin M production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects oncostatin M production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific oncostatin M production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002058,,,,,,,,,,,,,,,,,,,,,,,,oncostatin M release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific oncostatin M production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_1110191,epitope specific IL-13 release by T cells,,A biological process where T cells produce IL-13 resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/OBI_0001193|http://purl.obolibrary.org/obo/GO_0032616,,,,,,,,,,,,,,,,,,,A biological process where T cells produce IL-13 resulting from the recognition of a T cell epitope.,IEDB,,,,,,epitope specific IL-13 release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110191,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific IL-13 release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000964,in live cell assay,,An assay in which a measurement is made by observing entities located in a live cell.,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,An assay in which a measurement is made by observing entities located in a live cell.,,,,,,,in live cell assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000964,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,in live cell assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001636,grant,,A plan specification of organization A to give money to organization B so that B conducts investigations. Organization A has funder role and Organization B has research organization role.,false,,,http://purl.obolibrary.org/obo/IAO_0000104,,,,,,,,,,,,,,,,,"AR: Grant isn't a plan specification, it has a part which is a plan specification. See tracker: https://sourceforge.net/tracker/?func=detail&aid=3483338&group_id=177891&atid=886178",,A plan specification of organization A to give money to organization B so that B conducts investigations. Organization A has funder role and Organization B has research organization role.,OBI,,,,,"Discussed on Feb 13, 2012 dev call. Details see the tracker:
https://sourceforge.net/tracker/?func=detail&aid=3483338&group_id=177891&atid=886178",grant,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0500000,OBI:0001636,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,grant,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Group: OBI,,
http://purl.obolibrary.org/obo/OBI_0000849,organellar RNA extraction,,A RNA extraction process in which the desired output material is RNA in the organelle(s).,false,,,http://purl.obolibrary.org/obo/OBI_0666666,,,,,,,,,,,,,,,,,,,A RNA extraction process in which the desired output material is RNA in the organelle(s).,UPenn Group,,,,,,organellar RNA extraction,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000849,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,organellar RNA extraction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jie Zheng|Person: Chris Stoeckert,,
http://purl.obolibrary.org/obo/IAO_0000303,institutional identification,,A textual entity intended to identify a particular institution,false,,,http://purl.obolibrary.org/obo/IAO_0000300,,,,,,,,,,,,,,,,,,,A textual entity intended to identify a particular institution,,,,,,,institutional identification,,University of Colorado Denver School of Medicine,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000303,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,institutional identification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/NCBITaxon_10090,Mus musculus,house mouse|mouse,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_33208|http://purl.obolibrary.org/obo/NCBITaxon_39107,,,,house mouse|mouse,,,,,,,,,,,,,,,,,,,,,,Mus musculus,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:10090,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Mus musculus,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_1110012,occurrence of allergy,,The process of an allergic disease occurring in an organism.,false,,,http://purl.obolibrary.org/obo/OGMS_0000063,,,,,,,,,,,,,,,,,,,The process of an allergic disease occurring in an organism.,IEDB,,,,,,occurrence of allergy,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_1110011,,,,,,,,,,,,,,,,OBI:1110012,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,occurrence of allergy,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/IAO_0000327,table of contents,,A table that relates document parts to specific locations in a document (usually page numbers).  This is also a document part (subsumption there should be inferred).,false,,,http://purl.obolibrary.org/obo/IAO_0000306,,,,,,,,,,,,,,,,,,,A table that relates document parts to specific locations in a document (usually page numbers).  This is also a document part (subsumption there should be inferred).,,,,,,,table of contents,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000327,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,table of contents,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0000060,trial monitor role,trial monitor,"a responsible party involved in planning, overseeing the conduct of a study or study component, and interpreting data from a study",false,,,http://purl.obolibrary.org/obo/OBI_0000102,,,,trial monitor,,,,,,,,,,,,,"CDISC definition:  Person employed by the sponsor or CRO who is responsible for determining that a trial is being conducted in accordance with the protocol and GCP guidance. NOTE: A monitor's duties may include, but are not limited to, helping to plan and initiate a trial, assessing the conduct of trials, and assisting in data analysis, interpretation and extrapolation. Clinical Research Associate:  Primary representative of the sponsor; monitors progress of investigator sites participating in a clinical study.",,"a responsible party involved in planning, overseeing the conduct of a study or study component, and interpreting data from a study",,,,,,,trial monitor role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000060,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,trial monitor role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0000827,pill,,A dose of medicine or placebo in the form of a small pellet.,false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,,,,,,,,,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,,A dose of medicine or placebo in the form of a small pellet.,http://www.golovchenko.org/cgi-bin/wnsearch?q=pill#2n,,,,,,pill,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000827,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,pill,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_1110184,epitope specific GM-CSF release by T cells,,A biological process where T cells produce GM-CSF resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0032604|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,,,A biological process where T cells produce GM-CSF resulting from the recognition of a T cell epitope.,IEDB,,,,,,epitope specific GM-CSF release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110184,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific GM-CSF release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000245,organization,,"An entity that can bear roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members.",false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,"An entity that can bear roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members.",GROUP: OBI,,,,,"BP: The definition summarizes long email discussions on the OBI developer, roles, biomaterial and denrie branches. It leaves open if an organization is a material entity or a dependent continuant, as no consensus was reached on that.  The current placement as material is therefore temporary, in order to move forward with development. Here is the entire email summary, on which the definition is based:

1) there are organization_member_roles (president, treasurer, branch
editor), with individual persons as bearers

2) there are organization_roles (employer, owner, vendor, patent holder)

3) an organization has a charter / rules / bylaws, which specify what roles
there are, how they should be realized, and how to modify the
charter/rules/bylaws themselves.

It is debatable what the organization itself is (some kind of dependent
continuant or an aggregate of people). This also determines who/what the
bearer of organization_roles' are. My personal favorite is still to define
organization as a kind of 'legal entity', but thinking it through leads to
all kinds of questions that are clearly outside the scope of OBI.

Interestingly enough, it does not seem to matter much where we place
organization itself, as long as we can subclass it (University, Corporation,
Government Agency, Hospital), instantiate it (Affymetrix, NCBI, NIH, ISO,
W3C, University of Oklahoma), and have it play roles.

This leads to my proposal: We define organization through the statements 1 -
3 above, but without an 'is a' statement for now. We can leave it in its
current place in the is_a hierarchy (material entity) or move it up to
'continuant'. We leave further clarifications to BFO, and close this issue
for now.",organization,,PMID: 16353909.AAPS J. 2005 Sep 22;7(2):E274-80. Review. The joint food and agriculture organization of the United Nations/World Health Organization Expert Committee on Food Additives and its role in the evaluation of the safety of veterinary drug residues in foods.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000245,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,organization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Alan Ruttenberg|PERSON: Susanna Sansone|PERSON: Bjoern Peters|PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/CHEBI_33250,atom,,A chemical entity constituting the smallest component of an element having the chemical properties of the element.,false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,A chemical entity constituting the smallest component of an element having the chemical properties of the element.,,,,,,,atom,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:33250,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,atom,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001485,purified MHC molecule preparation,,A mixture containing MHC molecules that was purified to remove non-MHC molecular entities. ,false,,,http://purl.obolibrary.org/obo/OBI_0001633,,,,,,,,,,,,,,,,,,,A mixture containing MHC molecules that was purified to remove non-MHC molecular entities. ,,,,,,BP: 06/09/11: This needs to be coordinated with the broader treatment of 'purified materials' in general. ,purified MHC molecule preparation,,HLA A*0201 that was purified from cell lysate using an HLA class I specific antibody ,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001485,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,purified MHC molecule preparation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0400104,array scanner,,An processed material which acquires images of fluorescence (induced with lasers) from labeled molecules on the surface of the microarray chip,false,,,http://purl.obolibrary.org/obo/OBI_0000398,,,,,,,,,,,,,,,,,,,An processed material which acquires images of fluorescence (induced with lasers) from labeled molecules on the surface of the microarray chip,GROUP: MGED Ontology,,,,,,array scanner,,"GenePix 4200A, GenePix4000B",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/OBI_0000453|http://purl.obolibrary.org/obo/OBI_0000397,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400104,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,array scanner,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Trish Whetzel,,
http://purl.obolibrary.org/obo/OBI_0001239,transcription profiling by high throughput sequencing design,,"A study design in which sequencing technology (e.g. Solexa/454) is used to generate RNA sequence, analyse the transcibed regions of the genome, and/or to quantitate transcript abundance",false,,,http://purl.obolibrary.org/obo/OBI_0001430,,,,,,,,,,,,,,,,,,,"A study design in which sequencing technology (e.g. Solexa/454) is used to generate RNA sequence, analyse the transcibed regions of the genome, and/or to quantitate transcript abundance",Group: ArrayExpress production team,,,,,,transcription profiling by high throughput sequencing design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001331,,,,,,,,,,,,,,,,OBI:0001239,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,transcription profiling by high throughput sequencing design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001572,obsolete cell bound MHC binding constant determination assay,,An assay that measures the affinity of a ligand to MHC moleculs bound to the cell surface and that quantifies the affinity with a binding constant.,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,An assay that measures the affinity of a ligand to MHC moleculs bound to the cell surface and that quantifies the affinity with a binding constant.,IEDB,,,,,,obsolete cell bound MHC binding constant determination assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,OBI:0001572,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete cell bound MHC binding constant determination assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters,,
http://purl.obolibrary.org/obo/IAO_0000091,obsolete_report element,,"A report element is a narrative object in which information is presented and consumed by a human being, and is part of a report. Examples of report elements are figure (dot plot), table, text portion (may include a movie or audio clip on a web page).",true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,"A report element is a narrative object in which information is presented and consumed by a human being, and is part of a report. Examples of report elements are figure (dot plot), table, text portion (may include a movie or audio clip on a web page).",GROUP:OBI|OBI_0000001,,,,,"There will be some issue here about whether these are defined classes. As intended these are meant to denote the parts of the report that are not textual but are typically boxed and set within the text, labelled with some identifier, and referred to in the text|2009-08-10 Alan Ruttenberg: Larry Hunter suggests that this be obsoleted and replaced by 'textual entity' and 'figure'. Alan restored as there are OBI dependencies and this merits further discussion|2009-03-16: was report display element with definition: A report display element is a narrative object that is part of a report. Report display elements are set off from the textual parts of a report and are typically given a label(e.g. Figure 2) which is used to refer to the element from the text. Typically the 2d layout is part of the identity of such elements.|Replaced by textual entity and figure|2009-03-16: work has been done on this term during during the OBI workshop winter 2009 and the current definition was considered acceptable for use in OBI. If there is a need to modify this definition please notify OBI.|2009-03-16: needs some more work (clarify relations).",obsolete_report element,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,IAO:0000091,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_report element,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Allyson Lister|PERSON: Alan Ruttenberg|PERSON: Melanie Courtot,,
http://purl.obolibrary.org/obo/IAO_0000034,time trigger,,revisit?,false,,,http://purl.obolibrary.org/obo/IAO_0000001,,,,,,,,,,,,,,,,,,,revisit?,OBI_0000331|OBI branch derived,,,,,,time trigger,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000124,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000034,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,time trigger,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0001094,plate shaker,,A device that provides shaking motion for microplates.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A device that provides shaking motion for microplates.,PERSON: Erik Segerdell,,,,,,plate shaker,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000379,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001094,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,plate shaker,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0400084,photomultiplier tube,,"A photomultiplier is a device that is normally in the form of a tube, that uses a photocathode to convert photons into photoelectrons which are then amplified. PMTs are typically used to detect SSC and fluorescent parameters. Cytometers have a PMT for each color they can collect.",false,,,http://purl.obolibrary.org/obo/OBI_0000967|http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,"A photomultiplier is a device that is normally in the form of a tube, that uses a photocathode to convert photons into photoelectrons which are then amplified. PMTs are typically used to detect SSC and fluorescent parameters. Cytometers have a PMT for each color they can collect.",http://cyto.mednet.ucla.edu/Protocols/flow.htm,,,,,,photomultiplier tube,,R9647 by manufactured by Hamamatsu,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000453|http://purl.obolibrary.org/obo/OBI_0000370|http://purl.obolibrary.org/obo/OBI_0000395,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400084,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,photomultiplier tube,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0001301,cell culture analyte detection bioassay measuring epitope specific interleukin-16 production by T cells,IL-16 release|bioassay,An assay of epitope specific interleukin-16 production by T cells that uses a cell culture analyte detection bioassay.,false,,,http://purl.obolibrary.org/obo/OBI_0001280,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-16 production by T cells that uses a cell culture analyte detection bioassay.,IEDB,,,,,,cell culture analyte detection bioassay measuring epitope specific interleukin-16 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001301,,,,,,,,,,,,,,,,,,,,,,,,IL-16 release|bioassay,,,,,,,,,,,,,,,,,,,,,,cell culture analyte detection bioassay measuring epitope specific interleukin-16 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001863,shotgun bisulfite-seq assay,whole genome bisulfite sequencing|Shotgun bisulfite sequencing|whole-genome shotgun bisulfite sequencing|WGBS|WGSBS,A bisulfite sequencing assay that identifies methylated cytosines across the genome using high throughput sequencing.,false,,,http://purl.obolibrary.org/obo/OBI_0000748,,,,whole genome bisulfite sequencing|Shotgun bisulfite sequencing|whole-genome shotgun bisulfite sequencing|WGBS|WGSBS,,,,,,,,,,,,,,,A bisulfite sequencing assay that identifies methylated cytosines across the genome using high throughput sequencing.,Cokus et al. Shotgun bisulfite sequencing of the Arabidopsis genome reveals DNA methylation patterning. Nature. 2008 Mar 13;452(7184):215-9. [PMID:18278030],,,,,,shotgun bisulfite-seq assay,,Cokus et al. Shotgun bisulfite sequencing of the Arabidopsis genome reveals DNA methylation patterning. Nature. 2008 Mar 13;452(7184):215-9. [PMID:18278030].,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000711,http://purl.obolibrary.org/obo/OBI_0400114,,,,,,,,,,,,,,,OBI:0001863,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,shotgun bisulfite-seq assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/CL_0000084,T cell,,A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.,false,,,http://purl.obolibrary.org/obo/CL_0000542,,,,,,,,,,,,,,,,,,,A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.,,,,,,,T cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CL:0000084,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/cl.owl,,,,,,,,,,,,,,,,,,,T cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001258,ChIP-seq design,,"A study design which aims to identify protein and DNA interactions using a combination of chromatin immunoprecipitation and high throughput sequencing. Massively parallel sequence analyses are used in conjunction with whole-genome sequence databases to analyze the interaction pattern of any protein with DNA, or the pattern of any epigenetic chromatin modifications.",false,,,http://purl.obolibrary.org/obo/OBI_0001425,,,,,,,,,,,,,,,,,,,"A study design which aims to identify protein and DNA interactions using a combination of chromatin immunoprecipitation and high throughput sequencing. Massively parallel sequence analyses are used in conjunction with whole-genome sequence databases to analyze the interaction pattern of any protein with DNA, or the pattern of any epigenetic chromatin modifications.",http://en.wikipedia.org/wiki/Chip-Sequencing,,,,,,ChIP-seq design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001234|http://purl.obolibrary.org/obo/OBI_0001398,,,,,,,,,,,,,,,,OBI:0001258,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ChIP-seq design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001056,DNA synthesizer,,An oligonucleotide synthesizer that is used to custom-build DNA molecules to contain a particular sequence of nucleotides.,false,,,http://purl.obolibrary.org/obo/OBI_0400113,,,,,,,,,,,,,,,,,,,An oligonucleotide synthesizer that is used to custom-build DNA molecules to contain a particular sequence of nucleotides.,http://www.globalspec.com/LearnMore/Labware_Scientific_Instruments/Clinical_Research_Labware/DNA_Synthesizers,,,,,,DNA synthesizer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001056,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNA synthesizer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001123,microdissection instrument,,A device that is used for the dissection of tissues under magnification.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A device that is used for the dissection of tissues under magnification.,http://medical-dictionary.thefreedictionary.com/microdissection,,,,,,microdissection instrument,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000379,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,microdissection instrument,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001147,cell culture expansion,,a processual entity that results in the increase of cell numbers,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,"BP:
add it as subclass of 'cell culturing'
JZ:
No 'cell culturing' in OBI
Has term 'cell co-culturing' and  'maintaining cell culture'. Don't think either of it fit. So leave the term under process.",,a processual entity that results in the increase of cell numbers,MO_758 grow,,,,,including grow of yeast and bacteria,cell culture expansion,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001147,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cell culture expansion,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000950,paraffin specimen,,a specimen that is output of a paraffin storage process in which specimen is embedded in paraffin,false,,,http://purl.obolibrary.org/obo/OBI_0001472,,,,,,,,,,,,,,,,,,,a specimen that is output of a paraffin storage process in which specimen is embedded in paraffin,MO_990 paraffin_sample,,,,,,paraffin specimen,,liver tissue embedded in paraffin,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000950,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,paraffin specimen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Chris Stoeckert|PERSON: Jie Zheng,,
http://purl.obolibrary.org/obo/NCBITaxon_7955,Danio rerio,zebrafish|leopard danio|zebra fish|zebra danio,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_117571,,,,zebrafish|leopard danio|zebra fish|zebra danio,,,,,,,,,,,,,,,,,,,,,,Danio rerio,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:7955,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Danio rerio,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0400069,Luminex 100,,The Luminex 100 is a flow_cytometer_analyser manufactured by Luminex. It is a single laser system (575 nm) with avalanche photodiodes in red and infrared and a single PMT for fluorescence. The flow chamber is a square quartz cuvette.,false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,,,,,,,,,,,,,,,,The Luminex 100 is a flow_cytometer_analyser manufactured by Luminex. It is a single laser system (575 nm) with avalanche photodiodes in red and infrared and a single PMT for fluorescence. The flow chamber is a square quartz cuvette.,http://www.luminexcorp.com/products/luminex_100IS.html,,,,,,Luminex 100,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400069,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Luminex 100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0001954,ChIP assay,chromatin immunoprecipitation assay,"An assay in which protein-DNA complexes are extracted from short regions of chromatin and are reversibly cross linked, immunoprecipitated with antibodies or tags, purified, and amplified with the aim of analysis gene- and promoter-specific known targets",false,,,http://purl.obolibrary.org/obo/OBI_0002020|http://purl.obolibrary.org/obo/OBI_0001956,,http://purl.obolibrary.org/obo/OBI_0001234|http://purl.obolibrary.org/obo/OBI_0001398,,chromatin immunoprecipitation assay,,,,,,,,,,,,,"as per user (pployd) request and proposal by Alan Ruttenberg
http://sourceforge.net/p/obi/obi-terms/707/",,"An assay in which protein-DNA complexes are extracted from short regions of chromatin and are reversibly cross linked, immunoprecipitated with antibodies or tags, purified, and amplified with the aim of analysis gene- and promoter-specific known targets","adapted from CHS protocols, wikipedia, life tech, ChIP-seq term definition",,,,,,ChIP assay,,"PMID: 6379641
Gilmour & Lis. Proc Natl Acad Sci U S A. 1984 Jul;81(14):4275-9.
and can be found linked from here:
",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000690,,,,,,,,,,,,,,,,OBI:0001954,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ChIP assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/IAO_0000590,written name,,A textual entity that denotes a particular in reality.,false,,,http://purl.obolibrary.org/obo/IAO_0000300,,,,,,,,,,,,,,,,,"The qualifier ""written"" is to set it apart from spoken names.  Also, note the restrictions to particulars.  We are not naming universals.   We could however, be naming, attributive collections which are particulars, so ""All people located in the boundaries of the city of Little Rock, AR on June 18, 2011 at 9:50a CDT"" would be a name.",,A textual entity that denotes a particular in reality.,http://code.google.com/p/information-artifact-ontology/issues/detail?id=114,,,,,,written name,,"""The Eiffel Tower""|""Bill Clinton""|""United States of America""",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000590,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,written name,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bill Hogan,,
http://purl.obolibrary.org/obo/OBI_0400064,laser,light amplification by the stimulated emission of radiation,"A laser (acronym for light amplification by the stimulated emission of radiation) is a light source that emits photons of the same characteristics in a coherent beam. A laser uses a solid, liquid or gaseous lasing medium, that contains molecules, of which some atoms have electrons that emit photons of the same frequency when falling back to their normal orbital after excitation (pumping) by external means A laser is the most common way to irradiate a cell in a flow cytometer.",false,,,http://purl.obolibrary.org/obo/OBI_0400065,,,,light amplification by the stimulated emission of radiation,,,,,,,,,,,,,,,"A laser (acronym for light amplification by the stimulated emission of radiation) is a light source that emits photons of the same characteristics in a coherent beam. A laser uses a solid, liquid or gaseous lasing medium, that contains molecules, of which some atoms have electrons that emit photons of the same frequency when falling back to their normal orbital after excitation (pumping) by external means A laser is the most common way to irradiate a cell in a flow cytometer.",John Quinn|http://en.wikipedia.org/wiki/Laser,,,,,,laser,,A laser is the most common way to irradiate a cell in a flow cytometer.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400064,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,laser,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0302911,validation,,a planned process with objective to check that the accuracy or the quality of a claim or prediction  satisfies some criteria and which is assessed by comparing with independent results,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,,,a planned process with objective to check that the accuracy or the quality of a claim or prediction  satisfies some criteria and which is assessed by comparing with independent results,adapted from wordnet (wkipedia),,,,,,validation,,PMID: 18557814 . Chemical and genetic validation of dihydrofolate reductase-thymidylate synthase as a drug target in African trypanosomes. Mol Microbiol. 2008 Jun 16.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302911,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,validation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001193,epitope specific cytokine production by T cells,,A process of cytokine production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of cytokine production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific cytokine production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001193,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific cytokine production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0002072,assay measuring qualitiative binding of a MHC:ligand complex,qualitative binding|binding assay,A MHC:ligand binding assay that detects qualitative binding.,false,,,http://purl.obolibrary.org/obo/OBI_1110126,,,,,,,,,,,,,,,,,,,A MHC:ligand binding assay that detects qualitative binding.,IEDB,,,,,,assay measuring qualitiative binding of a MHC:ligand complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002072,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|binding assay,,,,,,,,,,,,,,,,,,,,,,assay measuring qualitiative binding of a MHC:ligand complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0200193,background corrected data visualization,,A data visualization which has input of a background corrected data set and produces an output of a report graph which is capable of rendering data of this type.,false,,,http://purl.obolibrary.org/obo/OBI_0200111,,,,,,,,,,,,,,,,,,,A data visualization which has input of a background corrected data set and produces an output of a report graph which is capable of rendering data of this type.,,,,,,,background corrected data visualization,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200193,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,background corrected data visualization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Monnie McGee,,
http://purl.obolibrary.org/obo/GO_0002534,cytokine production involved in inflammatory response,,"The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.",,,,,,,cytokine production involved in inflammatory response,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0002534,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,cytokine production involved in inflammatory response,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000913,promoter activity detection by reporter gene assay,,An assay in which the activity of a promoter in a cell is monitored by using a reporter gene that was inserted in a genomic location under control of the promoter and whose expression can be easily detected based on qualities or functions of the gene.,false,,,http://purl.obolibrary.org/obo/OBI_0001146,,,,,,,,,,,,,,,,,,,An assay in which the activity of a promoter in a cell is monitored by using a reporter gene that was inserted in a genomic location under control of the promoter and whose expression can be easily detected based on qualities or functions of the gene.,IEDB,,,,,,promoter activity detection by reporter gene assay,,"A T cell hybridoma in which the beta-galactosidase gene (lacZ) was inserted under the control of the IL-2 promoter, is detected by adding the X-gal substrate which when cleaved by lacZ results in detectable blue color.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CL_0000000,,,,OBI:0000913,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,promoter activity detection by reporter gene assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0002039,assay for transposase-accessible chromatin using sequencing,ATAC-seq assay|ATAC-seq,"An assay to capture the location of open chromatin, DNA-binding proteins, individual nucleosomes and chromatin compaction at nucleotide resolution by Tn5 transposase insertion.",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,ATAC-seq assay|ATAC-seq,,,,,,,,,,,,,,,"An assay to capture the location of open chromatin, DNA-binding proteins, individual nucleosomes and chromatin compaction at nucleotide resolution by Tn5 transposase insertion.","Buenrostro JD, Giresi PG, Zaba LC, Chang HY, and Greenleaf WJ. (2013) ""Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position."" Nature Methods",,,,,,assay for transposase-accessible chromatin using sequencing,,"Kasinathan et al., (February 2014). ""High-resolution mapping of transcription factor binding sites on natitve chromatin."" Nat Methods 11(2):203-9. doi: 10.1038/nmeth.2766.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002039,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,assay for transposase-accessible chromatin using sequencing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://www.geneontology.org/formats/oboInOwl#SynonymType,SynonymType,,,false,,,http://purl.obolibrary.org/obo/IAO_0000102,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,oboInOwl:SynonymType,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000815,Berichrom(r) Antithrombin III (A) Kit,,"For the chromogenic determination of antithrombin III. Autoanalyzer method for undiluted samples. For the quantitative chromogenic determination of the functional activity of antithrombin III in plasma on autoanalyzers for the diagnosis of diminished AT III synthesis, increased consumption, and for monitoring substitution therapy. Berichrom(r) Antithrombin III (A) is used for the rapid determination of the physiologically active antithrombin III and permits the diagnosis of congenital and acquired antithrombin III deficiency, a condition frequently associated with an increased risk of thrombosis. Acquired antithrombin III deficiencies frequently occur due to consumption following major operations or due to disseminated intravascular coagulation (DIC) in cases of septicaemia, nephroses, liver parenchymal damage (hepatitis, drug intoxication, alcoholism) and estrogen-containing contraceptives. The test permits early detection of patients at increased risk for thrombosis. Kit contains: 6 x for 5.0 mL Thrombin (bovine), 3 x for 3.0 mL Substrate Reagent, 1 x 30.0 mL Buffer Solution",false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,,,,,,,,,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,,"For the chromogenic determination of antithrombin III. Autoanalyzer method for undiluted samples. For the quantitative chromogenic determination of the functional activity of antithrombin III in plasma on autoanalyzers for the diagnosis of diminished AT III synthesis, increased consumption, and for monitoring substitution therapy. Berichrom(r) Antithrombin III (A) is used for the rapid determination of the physiologically active antithrombin III and permits the diagnosis of congenital and acquired antithrombin III deficiency, a condition frequently associated with an increased risk of thrombosis. Acquired antithrombin III deficiencies frequently occur due to consumption following major operations or due to disseminated intravascular coagulation (DIC) in cases of septicaemia, nephroses, liver parenchymal damage (hepatitis, drug intoxication, alcoholism) and estrogen-containing contraceptives. The test permits early detection of patients at increased risk for thrombosis. Kit contains: 6 x for 5.0 mL Thrombin (bovine), 3 x for 3.0 mL Substrate Reagent, 1 x 30.0 mL Buffer Solution",WEB:http://www.dadebehring.com/edbna2/ebusiness/products/productDetail.jsp?sDiscipline=Hemostasis&FirstLevelOID=-13075&sCategory_Name=BCS&SecondLevelOID=-13895&ThirdLevelOID=-13904&selectedProductType=H-Assays+-+non+US&sProductName=OWWR15&PROD_OID=44198@2009/08/06,,,,,,Berichrom(r) Antithrombin III (A) Kit,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000815,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Berichrom(r) Antithrombin III (A) Kit,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0000140,obsolete_label role,label,Label role is a role which inheres in a material entity and which is realized in a detection of label assay,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,label,,,,,,,,,,,,,,,Label role is a role which inheres in a material entity and which is realized in a detection of label assay,OBI,,,,,"MHB (9-26-12): consider deprecation of this class and replacement with REO:'molecular label role'|Nucleotides synthesized with the incorporation of biotin were used to synthesize cDNA, which was then detected by adding fluorochrome-conjugated anti-biotin antibody.  the fluorochrome bears label role, the antibody bears detector role, the biotin bears reporter role. may need to change the terms following discussion|need to add a restriction that the material entity has the disposition / quality that permits it to be detected, and one way to say this (BP) is that the entity is such that an assay exists that detects the presence of the material entity|we need to sort out probe, detector and reporter.  See https://sourceforge.net/tracker/index.php?func=detail&amp;aid=1866458&amp;group_id=177891&amp;atid=886178",obsolete_label role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000428,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000228,,,,,,,,,,,,,,,,,,OBI:0000140,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_label role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Role Branch,http://purl.obolibrary.org/obo/REO_0000171,
http://purl.obolibrary.org/obo/OBI_0001433,radio immuno assay measuring epitope specific interferon-gamma production by T cells,IFNg release|radio immuno assay (RIA),An assay of epitope specific interferon-gamma production by T cells that uses a radio immuno assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001414,,,,,,,,,,,,,,,,,,,An assay of epitope specific interferon-gamma production by T cells that uses a radio immuno assay.,IEDB,,,,,,radio immuno assay measuring epitope specific interferon-gamma production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001433,,,,,,,,,,,,,,,,,,,,,,,,IFNg release|radio immuno assay (RIA),,,,,,,,,,,,,,,,,,,,,,radio immuno assay measuring epitope specific interferon-gamma production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0200180,spread calculation objective,,"is a data transformation objective whereby the aim is to the calculate the spread of a dataset, spread is a descriptive statistic which describes the variability of values in a data set ",false,,,http://purl.obolibrary.org/obo/OBI_0200166,,,,,,,,,,,,,,,,,,,"is a data transformation objective whereby the aim is to the calculate the spread of a dataset, spread is a descriptive statistic which describes the variability of values in a data set ",,,,,,Awaiting English definition from Monnie McGee,spread calculation objective,,"Spread calculation can be achieved by use of a standard deviation, which measures distance from the mean",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200180,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,spread calculation objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Person:Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0000965,lyophilized specimen,,a specimen that is output of a lyophilization storage process in which specimen is lyophilized for storage.,false,,,http://purl.obolibrary.org/obo/OBI_0001472,,,,,,,,,,,,,,,,,,,a specimen that is output of a lyophilization storage process in which specimen is lyophilized for storage.,MO_589 freeze_dried_sample,,,,,,lyophilized specimen,,freezing dried DNA,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000965,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,lyophilized specimen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Chris Stoeckert|PERSON: Jie Zheng,,
http://purl.obolibrary.org/obo/OBI_0302888,washing,,washing is a process by which a material entity acting as  contaminant (e.g. excess staining reagent) is removed by application of one or more cycles of solution in flow.,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,washing is a process by which a material entity acting as  contaminant (e.g. excess staining reagent) is removed by application of one or more cycles of solution in flow.,OBI-Branch,,,,,,washing,,PMID: 6874122. Dialysis leucopenia--no correction after prolonged washing of the membrane. Int J Artif Organs. 1983 May;6(3):113-4.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/BFO_0000040,http://purl.obolibrary.org/obo/BFO_0000040,,,OBI:0302888,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,washing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001044,angiograph,,A device that records the patterns of pulse waves inside blood vessels.,false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,A device that records the patterns of pulse waves inside blood vessels.,http://medical-dictionary.thefreedictionary.com/angiograph,,,,,,angiograph,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453|http://purl.obolibrary.org/obo/OBI_0000368,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001044,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,angiograph,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0400111,hybridization station,,"A device which is used to maintain the temperature of one or more hybridization_chamber(s) at a defined, constant temperature.",false,,,http://purl.obolibrary.org/obo/OBI_0001034|http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,"A device which is used to maintain the temperature of one or more hybridization_chamber(s) at a defined, constant temperature.",MO_497 hybridization station,,,,,,hybridization station,,Labnet Problot12,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400111,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,hybridization station,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Trish Whetzel,,
http://purl.obolibrary.org/obo/IAO_0000592,software module,, A software module is software composed of a collection of software methods.,false,,,http://purl.obolibrary.org/obo/IAO_0000010,,,,,,,,,,,,,,,,,,, A software module is software composed of a collection of software methods.,http://code.google.com/p/information-artifact-ontology/issues/detail?id=80,,,,,,software module,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000592,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,software module,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Michel Dumontier|PERSON: Melanei Courtot,,
http://purl.obolibrary.org/obo/OBI_0001713,B cell epitope specific opsonization,,opsonization resulting from antibody binding to epitope,false,,,http://purl.obolibrary.org/obo/GO_0008228,,,,,,,,,,,,,,,,,Date: 2012-05-03; Spreadsheet: BcellAssays.xls; Worksheet: Especific template; Mapping: ebcell_specific_mappings.owl,,opsonization resulting from antibody binding to epitope,IEDB (QTT),,,,,,B cell epitope specific opsonization,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001713,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,B cell epitope specific opsonization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0600004,human subject enrollment,,A planned process with the objective to obtain a population of human subjects to participate in an investigation by determining eligibility of subjects and obtaining informed consent.,false,,,http://purl.obolibrary.org/obo/OBI_0001928,,,,,,,,,,,,,,,,,criteria come from plan / clinical trial branch,,A planned process with the objective to obtain a population of human subjects to participate in an investigation by determining eligibility of subjects and obtaining informed consent.,IEDB,,,,,"As with group assignment, should the specified output here be an organism which bears a role",human subject enrollment,,enlisting familiy members of HIV patients into a study,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000810,,,,,,,,,,,,,,,,OBI:0600004,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,human subject enrollment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001278,DNA methylation profiling by array design,,A study design in which the methylation state of DNA is determined and is compared between samples using array technology.,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,A study design in which the methylation state of DNA is determined and is compared between samples using array technology.,GROUP: ArrayExpress production team,,,,,,DNA methylation profiling by array design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001234,,,,,,,,,,,,,,,,OBI:0001278,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNA methylation profiling by array design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/CHEBI_33696,nucleic acid,,"A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid.",false,,,http://purl.obolibrary.org/obo/CHEBI_33839,,,,,,,,,,,,,,,,,,,"A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid.",,,,,,,nucleic acid,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:33696,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,nucleic acid,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0600065,obsolete_defined processes,,"Place holder class, see editor note",true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,"Place holder class, see editor note",OBI branch derived,,,,,"Remove to simplify OBI release
Discussed on 2012 Ann Arbor OBI wokshop",obsolete_defined processes,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000121,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000226,,,,,,,,,,,,,,,,,,OBI:0600065,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_defined processes,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0001648,cross blocking assay measuring binding of a B cell epitope:antibody complex,qualitative binding|cross blocking,A B cell epitope qualitative binding to antibody assay that uses an antibody cross-blocking assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001703,,,,,,,,,,,,,,,,,,,A B cell epitope qualitative binding to antibody assay that uses an antibody cross-blocking assay.,IEDB,,,,,,cross blocking assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001648,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|cross blocking,,,,,,,,,,,,,,,,,,,,,,cross blocking assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000131,molecular feature identification objective,,"Molecular_feature_identification_objective is a biological_feature_identification_objective role describing a study designed to examine or characterize molecular features of a biological system, e.g. expression profiling, copy number of molecular components, epigenetic modifications.",false,,,http://purl.obolibrary.org/obo/OBI_0000015,,,,,,,,,,,,,,,,,,,"Molecular_feature_identification_objective is a biological_feature_identification_objective role describing a study designed to examine or characterize molecular features of a biological system, e.g. expression profiling, copy number of molecular components, epigenetic modifications.",,,,,,,molecular feature identification objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000131,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,molecular feature identification objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0001521,ELISA measuring epitope specific granulocyte colony stimulating factor production by T cells,G-CSF release|ELISA,An assay of epitope specific granulocyte colony stimulating factor production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001600,,,,,,,,,,,,,,,,,,,An assay of epitope specific granulocyte colony stimulating factor production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific granulocyte colony stimulating factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001521,,,,,,,,,,,,,,,,,,,,,,,,G-CSF release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific granulocyte colony stimulating factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001169,age since birth measurement datum,,"An age measurement datum that is the result of the measurement of the age of an organism since birth, the process of emergence and separation of offspring from the mother.",false,,,http://purl.obolibrary.org/obo/OBI_0001167,,,,,,,,,,,,,,,,,,,"An age measurement datum that is the result of the measurement of the age of an organism since birth, the process of emergence and separation of offspring from the mother.",MO_710 birth,,,,,,age since birth measurement datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001169,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,age since birth measurement datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000957,self reported handedness assessment,,An assay in which a person makes a statement that indicates what handedness he has from a choice of different categories.,false,,,http://purl.obolibrary.org/obo/OBI_0000944,,,,,,,,,,,,,,,,,,,An assay in which a person makes a statement that indicates what handedness he has from a choice of different categories.,,,,,,,self reported handedness assessment,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000957,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,self reported handedness assessment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001993,assay measuring the off rate measurement [koff] of a MHC:ligand complex,off rate|binding assay|1/s,A MHC binding constant determination assay measuring binding off rate measurement data item (koff).,false,,,http://purl.obolibrary.org/obo/OBI_0001553,,,,,,,,,,,,,,,,,,,A MHC binding constant determination assay measuring binding off rate measurement data item (koff).,IEDB,,,,,,assay measuring the off rate measurement [koff] of a MHC:ligand complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001993,,,,,,,,,,,,,,,,,,,,,,,,off rate|binding assay|1/s,,,,,,,,,,,,,,,,,,,,,,assay measuring the off rate measurement [koff] of a MHC:ligand complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0100015,obsolete_anatomical entity,,"An anatomical entity is a material entity that is part of a multicellular organism, and which is large enough so that it forms an identifiable structure in the organism. Specifically, it excludes granular parts of the organism, such as atoms, molecules, cells, which can be removed from the organism without affecting it. It is defined as the union of 'multi-tissue structure', 'body substance' and 'portion of tissue'",true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,"An anatomical entity is a material entity that is part of a multicellular organism, and which is large enough so that it forms an identifiable structure in the organism. Specifically, it excludes granular parts of the organism, such as atoms, molecules, cells, which can be removed from the organism without affecting it. It is defined as the union of 'multi-tissue structure', 'body substance' and 'portion of tissue'",MO,,,,,"not super happy about liquids (blood, sperm), as they seem to be 'granular' somewhat, and not form a structure.|10/20/09: This class and all subclasses are currently problematic. They should all be imported from other OBO foundry ontologies. (FMA / CARO / UBERON). Currently two problems exist: There is no cross species anatomy that covers all the entities we need. Secondly: there is not good boundary between anatomical entities and smaller parts in FMA. Currently we will use anatomical entities as if they are valid across species.|equivalent classes
'portion of tissue' or 'multi-tissue structure' or 'portion of organism substance'

Superclasses
material_entity
part_of some organism|Biom call - January 2009 - Issues: 
parasites are not macroscopic part or organism. 
fetus is_a macroscopic part (but this is up for discussion)|13-02-2009:
Biomaterial branch: change of label and definition following discussions at the OBI winter meeting 2009. It was felt that 'macroscopic part of multicellular organism' introduce an impractical delineation.

IMPORTANT NOTE:  OBI 'anatomical entity' would essentially correspond to FMA 'material anatomical entity' rather than FMA 'physical anatomical entity'. OBI does not include 'immaterial anatomical entity' as it would clash with the parent class 'material entity'

DOCUMENTATION NOTE: OBI anatomical entity granularity level excludes cell and biological  molecules.",obsolete_anatomical entity,,"Tissue, organ, system, sperm, blood or body location (arm).",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000121,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000228,,,,,,,,,,,,,,,,,,OBI:0100015,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_anatomical entity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Tina Boussard|Philippe Rocca-Serra|Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001291,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-17 production by T cells,IL-17 release|RNA/DNA detection,An assay of epitope specific interleukin-17 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001295,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-17 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-17 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001291,,,,,,,,,,,,,,,,,,,,,,,,IL-17 release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-17 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001360,cytometric bead array assay measuring epitope specific interleukin-6 production by T cells,IL-6 release|cytometric bead array,An assay of epitope specific interleukin-6 production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001451,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-6 production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific interleukin-6 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001360,,,,,,,,,,,,,,,,,,,,,,,,IL-6 release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific interleukin-6 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001236,ELISA measuring epitope specific interleukin-22 production by T cells,IL-22 release|ELISA,An assay of epitope specific interleukin-22 production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001217,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-22 production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific interleukin-22 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001236,,,,,,,,,,,,,,,,,,,,,,,,IL-22 release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific interleukin-22 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000479,solid NMR probe,,An NMR probe that is designed to hold a solid sample.,false,,,http://purl.obolibrary.org/obo/OBI_0000516,,,,,,,,,,,,,,,,,NMR device,,An NMR probe that is designed to hold a solid sample.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400243,,,,,,solid NMR probe,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000479,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,solid NMR probe,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001846,ELISPOT assay measuring epitope specific interleukin-15 production by T cells,IL-15 release|ELISPOT,An assay of epitope specific interleukin-15 production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001292,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-15 production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific interleukin-15 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001846,,,,,,,,,,,,,,,,,,,,,,,,IL-15 release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific interleukin-15 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/PATO_0001548,quality of a liquid,,"A physical quality inhering in an entity exhibiting the physical characteristics of an amorphous (non-crystalline) form of matter between a gas and a solid that has a definite volume, but no definite shape.",false,,,http://purl.obolibrary.org/obo/PATO_0001237,,,,,,,,,,,,,,,,,,,"A physical quality inhering in an entity exhibiting the physical characteristics of an amorphous (non-crystalline) form of matter between a gas and a solid that has a definite volume, but no definite shape.",,,,,,,quality of a liquid,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001548,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,quality of a liquid,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0001547,quality of a gas,,A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity consisting of particles that have neither a defined volume nor defined shape.,false,,,http://purl.obolibrary.org/obo/PATO_0001237,,,,,,,,,,,,,,,,,,,A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity consisting of particles that have neither a defined volume nor defined shape.,,,,,,,quality of a gas,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001547,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,quality of a gas,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0001546,quality of a solid,,A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity characterized by particles arranged such that their shape and volume are relatively stable.,false,,,http://purl.obolibrary.org/obo/PATO_0001237,,,,,,,,,,,,,,,,,,,A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity characterized by particles arranged such that their shape and volume are relatively stable.,,,,,,,quality of a solid,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001546,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,quality of a solid,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001559,cell bound MHC direct binding assay measuring half life of a MHC:ligand complex using fluorescence detection,half life|cellular MHC/direct/fluorescence|min,A cell bound MHC ligand half life of binding determination assay that uses fluorescence detection to measure direct ligand binding.,false,,,http://purl.obolibrary.org/obo/OBI_0001990|http://purl.obolibrary.org/obo/OBI_0001499,,,,,,,,,,,,,,,,,,,A cell bound MHC ligand half life of binding determination assay that uses fluorescence detection to measure direct ligand binding.,IEDB,,,,,,cell bound MHC direct binding assay measuring half life of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001559,,,,,,,,,,,,,,,,,,,,,,,,half life|cellular MHC/direct/fluorescence|min,,,,,,,,,,,,,,,,,,,,,,cell bound MHC direct binding assay measuring half life of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0002081,specimens collected longitudinally,,A collection of specimens that was derived from the same source material entity at different time points in order to observe changes in that entity.,false,,,http://purl.obolibrary.org/obo/OBI_0002076,,,,,,,,,,,,,,,,,,,A collection of specimens that was derived from the same source material entity at different time points in order to observe changes in that entity.,"Bjoern Peters, OBI",,,,,Details see tracker: https://sourceforge.net/p/obi/obi-terms/778/,specimens collected longitudinally,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002081,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,specimens collected longitudinally,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0000431,injection into organ section,,A process in which an input substance is injected into a organ section. ,false,,,http://purl.obolibrary.org/obo/OBI_0000426,,http://purl.obolibrary.org/obo/OBI_0000434,,,,,,,,,,,,,,,,,A process in which an input substance is injected into a organ section. ,,,,,,,injection into organ section,,Staining a specimen of human lung tissue with hematoxylin and eosin in order as a preparative step in histology,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000431,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,injection into organ section,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Bjoern Peters,,
http://purl.obolibrary.org/obo/GO_0043234,protein complex,,Any macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.,false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,Any macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.,,,,,,,protein complex,,A ribosome is a protein complex,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/PR_000000001,,,,,,,,,,,,,,,,GO:0043234,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,protein complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200122,interquartile-range calculation,,The interquartile range is a descriptive statistics calculation defined as the difference between the 0.75 quantile and the 0.25 quantile for a set of data.,false,,,http://purl.obolibrary.org/obo/OBI_0200184|http://purl.obolibrary.org/obo/OBI_0200086,,http://purl.obolibrary.org/obo/OBI_0200078|http://purl.obolibrary.org/obo/OBI_0200180,,,,,,,,,,,,,,,From Monnie's file comments - need to add spread calculation role but they doesn't exist yet - (editor note added by James Jan 2008),,The interquartile range is a descriptive statistics calculation defined as the difference between the 0.75 quantile and the 0.25 quantile for a set of data.,PERSON: Monnie McGee,,,,,,interquartile-range calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,interquartile-range calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Monnie McGee,,
http://purl.obolibrary.org/obo/OBI_0000449,obsolete_defined_output,,"This is only a placeholder for defined classes, as are its siblings _defined_material and _defined protocol application.
Its children should be defined classes constructed as output of a process.",true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,"This is only a placeholder for defined classes, as are its siblings _defined_material and _defined protocol application.
Its children should be defined classes constructed as output of a process.",,,,,,,obsolete_defined_output,,example of subclass: normalized data set - A normalized data set is a data set that is produced as the output of a normalization data transformation.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000121,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000226,,,,,,,,,,,,,,,,,,OBI:0000449,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_defined_output,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot|PERSON: Alan Ruttenberg|PERSON: James Malone,,
http://purl.obolibrary.org/obo/IAO_0000141,obsolete_digital quality,,,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,,,,,,,"3/22/2009 Alan Ruttenberg, obsoleted per http://groups.google.com/group/information-ontology/browse_thread/thread/789ad4b7708d5cf4|Need to rework digital entity. Digital quality was suggested by Barry.",obsolete_digital quality,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,IAO:0000141,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_digital quality,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_1110049,allergy,,"is a disease in which an abnormally strong inflammatory immune response is triggered against non-self entities, and the immune response has no protective effect",false,,,http://purl.obolibrary.org/obo/OGMS_0000031,,,,,,,,,,,,,,,,,,,"is a disease in which an abnormally strong inflammatory immune response is triggered against non-self entities, and the immune response has no protective effect",IEDB,,,,,,allergy,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110049,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,allergy,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000442,obsolete_heart,,"The heart is a muscular organ found in all vertebrates that is responsible for pumping blood throughout the blood vessels by repeated, rhythmic contractions",true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,"The heart is a muscular organ found in all vertebrates that is responsible for pumping blood throughout the blood vessels by repeated, rhythmic contractions",http://en.wikipedia.org/wiki/Heart,,,,,"MC: should be imported|unused class. decided to be deprecated on Aug 2, 2010 dev call. Will be imported when need.",obsolete_heart,,Alan Ruttenberg's heart,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000002,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000230,,,,,,,,,,,,,,,,,,OBI:0000442,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_heart,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_1110150,51 chromium assay measuring epitope specific T cell killing,cytotoxicity|51 chromium,A T cell epitope specific killing assay performed in vitro that uses a chromium release assay.,false,,,http://purl.obolibrary.org/obo/OBI_0002062,,,,,,,,,,,,,,,,,,,A T cell epitope specific killing assay performed in vitro that uses a chromium release assay.,IEDB,,,,,,51 chromium assay measuring epitope specific T cell killing,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110150,,,,,,,,,,,,,,,,,,,,,,,,cytotoxicity|51 chromium,,,,,,,,,,,,,,,,,,,,,,51 chromium assay measuring epitope specific T cell killing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/GO_0007596,blood coagulation,,"The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.",false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,"The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.",,,,,,,blood coagulation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0007596,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,blood coagulation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001339,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-4 production by T cells,IL-4 release|RNA/DNA detection,An assay of epitope specific interleukin-4 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001450,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-4 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-4 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001339,,,,,,,,,,,,,,,,,,,,,,,,IL-4 release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-4 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000565,electrical conductivity detector,,"The electrical conductivity detector measures the conductivity of the mobile phase. There is usually background conductivity which must be backed-off by suitable electronic adjustments. If the mobile phase contains buffers, the detector gives a base signal that completely overwhelms that from any solute usually making detection impossible. Thus, the electrical conductivity detector a bulk property detector. and senses all ions whether they are from a solute or from the mobile phase. In order to prevent polarization of the sensing electrodes, AC voltages must be used and so it is the impedance not the resistance of the electrode system that is actually measured. From a physical chemistry stand point the conductivity of a solution is more important than its resistance. However, it is the resistance (impedance) of the electrode system that determines the current across it. The resistance of any conductor varies directly as its length and inversely as its cross sectional area.",false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,"The electrical conductivity detector measures the conductivity of the mobile phase. There is usually background conductivity which must be backed-off by suitable electronic adjustments. If the mobile phase contains buffers, the detector gives a base signal that completely overwhelms that from any solute usually making detection impossible. Thus, the electrical conductivity detector a bulk property detector. and senses all ions whether they are from a solute or from the mobile phase. In order to prevent polarization of the sensing electrodes, AC voltages must be used and so it is the impedance not the resistance of the electrode system that is actually measured. From a physical chemistry stand point the conductivity of a solution is more important than its resistance. However, it is the resistance (impedance) of the electrode system that determines the current across it. The resistance of any conductor varies directly as its length and inversely as its cross sectional area.",WEB:<http://www.chromatography-online.org/HPLC-Detectors/Electrical-Conductivity/rs83.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01239,,,,,,electrical conductivity detector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000565,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,electrical conductivity detector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000443,analyte assay,,"An assay with the objective to capture information about the presence, concentration, or amount of an analyte in an evaluant.",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,"An assay with the objective to capture information about the presence, concentration, or amount of an analyte in an evaluant.","PERSON:Bjoern Peters
PERSON:Helen Parkinson
PERSON:Philippe Rocca-Serra
PERSON:Alan Ruttenberg
GROUP:OBI Planned process branch",,,,,"2013-09-23: simplify equivalent axiom|Note: is_realization of some analyte role isn't always true, for example when there is none of the analyte in the evaluant. For the moment we are writing it this way, but when the information ontology is further worked out this will be replaced with a condition discussing the measurement.|logical def modified to remove expression below, as some analyte assays report below the level of detection, and therefore not a scalar measurement datum, replaced by measurement datum

and 
('has measurement unit label' some 'measurement unit label') and 
('is quality measurement of' some 'molecular concentration'))",analyte assay,,"example of usage: In lab test for blood glucose, the test is the assay, the blood bears evaluant_role and glucose bears the analyte role. The evaluant is considered an input to the assay and the information entity that records the measurement of glucose concentration the output",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000109,,,OBI:0000443,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,analyte assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000275,,,,,,,,,,,,,,,,"PERSON:Bjoern Peters, Helen Parkinson, Philippe Rocca-Serra, Alan Ruttenberg",,
http://purl.obolibrary.org/obo/OBI_0002078,specimen set collection process,,A specimen collection process that generates multiple specimens from one source (e.g. one organism) during a time period which for the purpose of the study can be considered to be taken at the same sampling time.,false,,,http://purl.obolibrary.org/obo/OBI_0000659,,,,,,,,,,,,,,,,,,,A specimen collection process that generates multiple specimens from one source (e.g. one organism) during a time period which for the purpose of the study can be considered to be taken at the same sampling time.,"OBIB, OBI",,,,,,specimen set collection process,,Collection of both blood and urine specimens in one clinical visit; Taking out liver and brain specimens during an autopsy.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002078,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,specimen set collection process,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000869,polyA RNA extract,,A RNA extract that is the output of an extraction process in which RNA molecules with poly A tail at its 3' end are purified.,false,,,http://purl.obolibrary.org/obo/OBI_0000880,,,,,,,,,,,,,,,,,,,A RNA extract that is the output of an extraction process in which RNA molecules with poly A tail at its 3' end are purified.,UPenn Group,,,,,,polyA RNA extract,,"Preparation of polyA RNA by cellulose-bound oligo-dT (Aviv, H., Leder, P. 1972. Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose. Proc. Nat. Acad. Sci. USA 69, 1408-1412.)",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000869,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000848,,,polyA RNA extract,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Chris Stoeckert|PERSON: Jie Zheng,,
http://purl.obolibrary.org/obo/OBI_1110046,organ harvesting,,The process of removing an organ from its source organism,false,,,http://purl.obolibrary.org/obo/OBI_0600014,,,,,,,,,,,,,,,,,,,The process of removing an organ from its source organism,IEDB,,,,,,organ harvesting,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110046,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,organ harvesting,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000788,fluorescently labeled MHC multimer,,"A complex of two or more linked MHC molecules including a fluorescent label that can be loaded with a ligand, and is used in flow cytometry assay to bind to T cell receptors of T cells specific for the ligand",false,,,http://purl.obolibrary.org/obo/OBI_0001936,,,,,,http://purl.obolibrary.org/obo/PATO_0000018,,,,,,,,,,,,,"A complex of two or more linked MHC molecules including a fluorescent label that can be loaded with a ligand, and is used in flow cytometry assay to bind to T cell receptors of T cells specific for the ligand",,,,,,,fluorescently labeled MHC multimer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/REO_0000280,,,,,,,,,,,,,,,,OBI:0000788,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0600038,,,fluorescently labeled MHC multimer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001486,disposition to be bound by an MHC protein complex,MHC ligand disposition,Is the disposition borne by a material entity that is realized in a process of being bound in the antigen binding grove of an MHC protein complex.,false,,,http://purl.obolibrary.org/obo/BFO_0000016,,,,MHC ligand disposition,,,,,,,,,,,,,,,Is the disposition borne by a material entity that is realized in a process of being bound in the antigen binding grove of an MHC protein complex.,IEDB,,,,,,disposition to be bound by an MHC protein complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001486,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,disposition to be bound by an MHC protein complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Jason Greenbaum, Randi Vita, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001483,cell collecting,,A planned process that collects cells from culture.,false,,,http://purl.obolibrary.org/obo/OBI_0600014,,http://purl.obolibrary.org/obo/OBI_0000639,,,,,,,,,,,,,,,,,A planned process that collects cells from culture.,MO_982 harvest,,,,,,cell collecting,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100060,,,,OBI:0001483,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cell collecting,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000839,labeled oligonucleotide,,a labeled oligonucleotide is a short nucleic acid which underwent a labeling process resulting in a radioactive isotope such as P32 or P33 added to its backbone for instance by end labeling with polynucleotide kinase which added radiolabeled ATP to the 5' end of oligonucleotide,false,,,http://purl.obolibrary.org/obo/OBI_0001936,,,,,,,,,,,,,,,,,,,a labeled oligonucleotide is a short nucleic acid which underwent a labeling process resulting in a radioactive isotope such as P32 or P33 added to its backbone for instance by end labeling with polynucleotide kinase which added radiolabeled ATP to the 5' end of oligonucleotide,,,,,,"2010-01-31: Philippe Rocca-Serra
placeholder",labeled oligonucleotide,,"",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/REO_0000280,,,,,,,,,,,,,,,,OBI:0000839,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0600038,,,labeled oligonucleotide,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/GO_0042575,DNA polymerase complex,,A protein complex that possesses DNA polymerase activity and is involved in template directed synthesis of DNA.,false,,,http://purl.obolibrary.org/obo/OBI_0000427|http://purl.obolibrary.org/obo/GO_0043234,,,,,,,,,,,,,,,,,,,A protein complex that possesses DNA polymerase activity and is involved in template directed synthesis of DNA.,,,,,,,DNA polymerase complex,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/GO_0034061,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0042575,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,DNA polymerase complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0042571,"immunoglobulin complex, circulating",antibody|antibody,"An immunoglobulin complex that is secreted into extracellular space and found in mucosal areas or other tissues or circulating in the blood or lymph. In its canonical form, a circulating immunoglobulin complex is composed of two identical heavy chains and two identical light chains, held together by disulfide bonds. Some forms of are polymers of the basic structure and contain additional components such as J-chain and the secretory component.",false,,,http://purl.obolibrary.org/obo/OBI_1110022|http://purl.obolibrary.org/obo/GO_0019814,,,,antibody,,,,,,,,,,,,,,,"An immunoglobulin complex that is secreted into extracellular space and found in mucosal areas or other tissues or circulating in the blood or lymph. In its canonical form, a circulating immunoglobulin complex is composed of two identical heavy chains and two identical light chains, held together by disulfide bonds. Some forms of are polymers of the basic structure and contain additional components such as J-chain and the secretory component.",,,,,,,"immunoglobulin complex, circulating",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0042571,,,,,,,,,,,,,,,,,,,,,,,,antibody,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,"immunoglobulin complex, circulating",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_1110036,JY cell line,,The JY cell line is an Epstein-Barr virus (EBV)-immortalised b cell lymphoblastoid line.(wikipedia),false,,,http://purl.obolibrary.org/obo/CLO_0009828,,,,,,,,,,,,,,,,,,,The JY cell line is an Epstein-Barr virus (EBV)-immortalised b cell lymphoblastoid line.(wikipedia),IEDB,,,,,,JY cell line,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110036,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,JY cell line,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0400097,Somacount,,"A Somacount is a flow_cytometer_analyser manufactured by Bently Instruments. It is a specialized tool for counting somatic cells in milk by specifically staining them with Ethidium Bromide and counting the cells that fluoresce. It has one laser, and the filters and a PMT for the single parameter. There are three sizes available, the 150, 300, and 500 with the number indicating the maximum number of cells that can be analysed per hour. The Somacount is an example of a very specific use cytometer; it exclusively counts somatic cells in milk.",false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,,,,,,,,,,,,,,,,"A Somacount is a flow_cytometer_analyser manufactured by Bently Instruments. It is a specialized tool for counting somatic cells in milk by specifically staining them with Ethidium Bromide and counting the cells that fluoresce. It has one laser, and the filters and a PMT for the single parameter. There are three sizes available, the 150, 300, and 500 with the number indicating the maximum number of cells that can be analysed per hour. The Somacount is an example of a very specific use cytometer; it exclusively counts somatic cells in milk.",http://www.bentleyinstruments.com/somacount.html#Anchor-Bentley-49575,,,,,,Somacount,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400097,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Somacount,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_1110015,Immunization in vivo,,Process of administering an object playing the role of immunogen to a living organism,false,,,http://purl.obolibrary.org/obo/OBI_1110094,,,,,,,,,,,,,,,,,,,Process of administering an object playing the role of immunogen to a living organism,IEDB,,,,,,Immunization in vivo,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100026,,,,,,,,,,,,,,,OBI:1110015,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Immunization in vivo,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001735,ELISA measuring the association constant [KA] of a B cell epitope:antibody complex,association constant KA|ELISA|1/nM,A B cell epitope equilibrium association constant (KA) determination assay that uses an enzyme-linked immunosorbent assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001719,,,,,,,,,,,,,,,,,,,A B cell epitope equilibrium association constant (KA) determination assay that uses an enzyme-linked immunosorbent assay.,IEDB,,,,,,ELISA measuring the association constant [KA] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001735,,,,,,,,,,,,,,,,,,,,,,,,association constant KA|ELISA|1/nM,,,,,,,,,,,,,,,,,,,,,,ELISA measuring the association constant [KA] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001421,epitope specific interferon-beta production by T cells,,A process of interferon-beta production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0032608|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of interferon-beta production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific interferon-beta production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001421,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific interferon-beta production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000559,liquid NMR probe,,An NMR probe that is designed to hold a liquid sample.,false,,,http://purl.obolibrary.org/obo/OBI_0000516,,,,,,,,,,,,,,,,,NMR device,,An NMR probe that is designed to hold a liquid sample.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400242,,,,,,liquid NMR probe,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000559,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,liquid NMR probe,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000590,Bruker 1mm MicroProbe,,"Over the past few years there has been a significantly growing demand for miniaturization in all areas ofmodern research and development. Evoked by many exciting applications, there is a need for analytical methods which require less amounts of sample. Bruker BioSpin meets this challenge with a revolutionary NMR probe design: The 1mm MicroProbe. It operates with disposable 1mm capillary sample tubes and the sample volume of 5 microliters enables the use of lowest amounts of sample to run all high resolution NMR experiments with outstanding sensitivity and up to 16 times faster measurements. Due to the TXI-type probe design, the z-gradient coil and the automatic matching and tuning accessory, the 1mm MicroProbe can be used for a wide variety of NMR experiments. The key advantages of this probe include:\n   up to 4 times higher mass sensitivity than 5mm conventional probes (with respect to the same sample amount)\n   excellent solvent suppression properties\n   virtually no salt effect\n   discrete samples in tubes that can be sealed and stored\n   automation accessory for sample preparation and handling available.",false,,,http://purl.obolibrary.org/obo/OBI_0000561,,,,,,,,,,,,,,,,,NMR probe,,"Over the past few years there has been a significantly growing demand for miniaturization in all areas ofmodern research and development. Evoked by many exciting applications, there is a need for analytical methods which require less amounts of sample. Bruker BioSpin meets this challenge with a revolutionary NMR probe design: The 1mm MicroProbe. It operates with disposable 1mm capillary sample tubes and the sample volume of 5 microliters enables the use of lowest amounts of sample to run all high resolution NMR experiments with outstanding sensitivity and up to 16 times faster measurements. Due to the TXI-type probe design, the z-gradient coil and the automatic matching and tuning accessory, the 1mm MicroProbe can be used for a wide variety of NMR experiments. The key advantages of this probe include:\n   up to 4 times higher mass sensitivity than 5mm conventional probes (with respect to the same sample amount)\n   excellent solvent suppression properties\n   virtually no salt effect\n   discrete samples in tubes that can be sealed and stored\n   automation accessory for sample preparation and handling available.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400194,,,,,,Bruker 1mm MicroProbe,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000590,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker 1mm MicroProbe,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000660,background corrected data set,,A data set that is produced as the output of a background correction data transformation.,false,,,http://purl.obolibrary.org/obo/IAO_0000100,,,,,,,,,,,,,,,,,,,A data set that is produced as the output of a background correction data transformation.,,,,,,,background corrected data set,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000660,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,background corrected data set,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot|PERSON: James Malone,,
http://purl.obolibrary.org/obo/UBERON_0002072,hypodermis,,"Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP].",false,,,http://purl.obolibrary.org/obo/CARO_0000043,,,,,,,,,,,,,,,,,,,"Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP].",,,,,,,hypodermis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UBERON:0002072,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uberon.owl,,,,,,,,,,,,,,,,,,,hypodermis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/NCBITaxon_33154,Opisthokonta,,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_2759,,,,,,,,,,,,,,,,,,,,,,,,,,Opisthokonta,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:33154,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Opisthokonta,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001334,epitope specific granulocyte colony stimulating factor production by T cells,,A process of granulocyte colony stimulating factor production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0071611|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of granulocyte colony stimulating factor production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific granulocyte colony stimulating factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001334,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific granulocyte colony stimulating factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0400019,charge plate,,"Part of the fluidics subsystem. Charge plates are used or sorters. They create an charged electric field when particles deemed to be desired for further analysis are shaken form the piexo electric crystal. The charged particles are drawn toward the charged plate, and the altered drop location causes the particles to fall into a collection tube. Charge plates enable sorting.",false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,"Part of the fluidics subsystem. Charge plates are used or sorters. They create an charged electric field when particles deemed to be desired for further analysis are shaken form the piexo electric crystal. The charged particles are drawn toward the charged plate, and the altered drop location causes the particles to fall into a collection tube. Charge plates enable sorting.","Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253",,,,,,charge plate,,LSR2 charge plate,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000383|http://purl.obolibrary.org/obo/OBI_0000374,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400019,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,charge plate,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0200088,Kaplan Meier,,"a nonparametric (actuarial) data transformation technique for estimating time-related events. It is a univariate analysis that estimates the probability of the proportion of subjects in remission at a particular time, starting from the initiation of active date (time zero), and takes into account those lost to follow-up or not yet in remission at end of study (censored)",false,,,http://purl.obolibrary.org/obo/OBI_0200194,,http://purl.obolibrary.org/obo/OBI_0200083,,,,,,,,,,,,,,,,,"a nonparametric (actuarial) data transformation technique for estimating time-related events. It is a univariate analysis that estimates the probability of the proportion of subjects in remission at a particular time, starting from the initiation of active date (time zero), and takes into account those lost to follow-up or not yet in remission at end of study (censored)",http://en.wikipedia.org/wiki/Kaplan%E2%80%93Meier_estimator,,,,,,Kaplan Meier,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200088,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Kaplan Meier,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Tina Boussard|PERSON: James Malone,,
http://purl.obolibrary.org/obo/OBI_0001383,detection of specific nucleic acids with complementary probes assay measuring epitope specific IP-10 production by T cells,CXCL10/IP-10 release|RNA/DNA detection,An assay of epitope specific IP-10 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001308,,,,,,,,,,,,,,,,,,,An assay of epitope specific IP-10 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific IP-10 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001383,,,,,,,,,,,,,,,,,,,,,,,,CXCL10/IP-10 release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific IP-10 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0400099,flow cytometer sorter,,A flow_cytometer_sorter is a flow_cytometer that analyzes and separates or sorts particles passing through (based on properties measured during analysis) to collect cells of interest.,false,,,http://purl.obolibrary.org/obo/OBI_0400044|http://purl.obolibrary.org/obo/OBI_0000932,,,,,,,,,,,,,,,,,,,A flow_cytometer_sorter is a flow_cytometer that analyzes and separates or sorts particles passing through (based on properties measured during analysis) to collect cells of interest.,http://www.flocyte.com/FRTP/Resources/flow_cytometry_glossary.htm,,,,,,flow cytometer sorter,,"BioSorter2000, LSR2",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/OBI_0000372,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0400079|http://purl.obolibrary.org/obo/OBI_0400065|http://purl.obolibrary.org/obo/OBI_0400153|http://purl.obolibrary.org/obo/OBI_0400082,,,,,,,,,,,,,,,,OBI:0400099,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,flow cytometer sorter,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Melanie Courtot|John Quinn,,
http://purl.obolibrary.org/obo/OBI_0302898,intentional overdosing,lethal injection,intentional overdosing is a process by which an excess dose of a chemical compound is given with the intent of causing death,false,,,http://purl.obolibrary.org/obo/OBI_0000919,,,,lethal injection,,,,,,,,,,,,,,,intentional overdosing is a process by which an excess dose of a chemical compound is given with the intent of causing death,OBI Biomaterial,,,,,,intentional overdosing,,"In vivo measurement of tumor blood oxygenation by near-infrared spectroscopy: immediate effects of pentobarbital overdose or carmustine treatment.
J Neurooncol. 1994;22(3):209-20. PMID: 7760097",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,OBI:0302898,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,intentional overdosing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001376,intracellular cytokine staining assay measuring epitope specific interleukin-3 production by T cells,IL-3 release|ICS,An assay of epitope specific interleukin-3 production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001406,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-3 production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-3 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001376,,,,,,,,,,,,,,,,,,,,,,,,IL-3 release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-3 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001680,Sos-recruitment assay ,SRS,"is a kind of yeast 2 hybrid system where mammalian guanyl nucleotide exchange factor (GEF) Sos is recruited to the Saccharomyces cerevisiae plasma membrane harboring a temperature-sensitive Ras GEF, Cdc25-2, allowing growth at the nonpermissive temperature. Using the Sos recruitment system, interacting proteins for targeted domain can be detected.",false,,,http://purl.obolibrary.org/obo/OBI_0000070|http://purl.obolibrary.org/obo/OBI_0001146,,,,SRS,,,,,,,,,,,,,add regulatory region DNA binding;GO:0043565;,,"is a kind of yeast 2 hybrid system where mammalian guanyl nucleotide exchange factor (GEF) Sos is recruited to the Saccharomyces cerevisiae plasma membrane harboring a temperature-sensitive Ras GEF, Cdc25-2, allowing growth at the nonpermissive temperature. Using the Sos recruitment system, interacting proteins for targeted domain can be detected.","adapted from the original publication by Aronheim et al, 1997. PMID: 9154808",,,,,,Sos-recruitment assay ,,"The Sos-recruitment system as a tool to analyze cellular localization of plant proteins: membrane localization of Arabidopsis thaliana PEPINO/PASTICCINO2.
Schönhofer-Merl S, Torres-Ruiz RA.
Mol Genet Genomics. 2010 May;283(5):439-49. Epub 2010 Mar 19.
PMID: 20300944",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001680,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Sos-recruitment assay ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra; Marcus Chibucos,,
http://purl.obolibrary.org/obo/OBI_0000509,electron capture detector,ECD,"The electron capture detector is a GC detector that uses a radioactive Beta emitter (electrons) to ionize some of the carrier gas and produce a current between a biased pair of electrodes. When organic molecules that contain electronegative functional groups, such as halogens, phosphorous, and nitro groups pass by the detector, they capture some of the electrons and reduce the current measured between the electrodes.",false,,,http://purl.obolibrary.org/obo/OBI_0000637,,,,ECD,,,,,,,,,,,,,,,"The electron capture detector is a GC detector that uses a radioactive Beta emitter (electrons) to ionize some of the carrier gas and produce a current between a biased pair of electrodes. When organic molecules that contain electronegative functional groups, such as halogens, phosphorous, and nitro groups pass by the detector, they capture some of the electrons and reduce the current measured between the electrodes.",WEB:<http://homepages.onsnet.nu/%7Ealkema/html/whatisgc.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01085,,,,,,electron capture detector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000509,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,electron capture detector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001427,transcription profiling by tiling array design,,"A study design in which gene expression on a genome-wide basis is evaluated, without bias toward coding or noncoding regions, using tiling arrays containing oligonucleotides that are either overlapping or spaced at regular intervals.",false,,,http://purl.obolibrary.org/obo/OBI_0001430,,,,,,,,,,,,,,,,,,,"A study design in which gene expression on a genome-wide basis is evaluated, without bias toward coding or noncoding regions, using tiling arrays containing oligonucleotides that are either overlapping or spaced at regular intervals.",MO_507 tiling_path_design,,,,,,transcription profiling by tiling array design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001331,,,,,,,,,,,,,,,,OBI:0001427,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,transcription profiling by tiling array design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001461,ELISA measuring epitope specific granzyme B release by T cells,granzyme B release|ELISA,A T cell epitope specific granzyme B release assay that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001436,,,,,,,,,,,,,,,,,,,A T cell epitope specific granzyme B release assay that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific granzyme B release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001461,,,,,,,,,,,,,,,,,,,,,,,,granzyme B release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific granzyme B release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0200036,Benjamini and Hochberg false discovery rate correction method,,A data transformation process in which the Benjamini and Hochberg method sequential p-value procedure  is applied with the aim of correcting false discovery rate,false,,,http://purl.obolibrary.org/obo/OBI_0200163,,http://purl.obolibrary.org/obo/OBI_0000791,,,,,,,,,,,,,,,,,A data transformation process in which the Benjamini and Hochberg method sequential p-value procedure  is applied with the aim of correcting false discovery rate,Helen Parkinson,,,,,"2011-03-31: [PRS]. 
specified input and output of dt which were missing",Benjamini and Hochberg false discovery rate correction method,,Statistical significance of the 8 most represented biological processes (GO level 4) among E7 6 month upregulated genes following analysis with DAVID software; Benjamini-Hochberg FDR (false discovery rate),,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000175,http://purl.obolibrary.org/obo/OBI_0000662|http://purl.obolibrary.org/obo/OBI_0001442,,,OBI:0200036,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Benjamini and Hochberg false discovery rate correction method,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra|Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0001661,chromatography assay measuring binding of a B cell epitope:antibody complex,qualitative binding|chromatography,A B cell epitope qualitative binding to antibody assay that uses an analytical chromatography assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001703,,,,,,,,,,,,,,,,,,,A B cell epitope qualitative binding to antibody assay that uses an analytical chromatography assay.,IEDB,,,,,,chromatography assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001661,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|chromatography,,,,,,,,,,,,,,,,,,,,,,chromatography assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000595,pulsed amperometric detector,PAD,"A chromatography detector as used by high-performance anion exchange chromatography that provides sensitive and specific detection of carbohydrates. Pulsed Electrochemical Detection (PED) allows simple, sensitive, and direct detection of numerous polar aliphatic compounds, especially carbohydrates. This technique exploits the electrocatalytic activity of noble metal electrode surfaces to oxidize various polar functional groups. In PED, multi-step potential-time waveforms at Au and Pt electrodes realize amperometric/coulometric detection while maintaining uniform and reproducible electrode activity. The response mechanisms in PED are dominated by the surface properties of the electrode, and, as a consequence, members of each chemical class of compounds produce virtually identical voltammetric responses. Thus, the full potential is realized when combined with high performance liquid chromatography (HPLC).",false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,PAD,,,,,,,,,,,,,,,"A chromatography detector as used by high-performance anion exchange chromatography that provides sensitive and specific detection of carbohydrates. Pulsed Electrochemical Detection (PED) allows simple, sensitive, and direct detection of numerous polar aliphatic compounds, especially carbohydrates. This technique exploits the electrocatalytic activity of noble metal electrode surfaces to oxidize various polar functional groups. In PED, multi-step potential-time waveforms at Au and Pt electrodes realize amperometric/coulometric detection while maintaining uniform and reproducible electrode activity. The response mechanisms in PED are dominated by the surface properties of the electrode, and, as a consequence, members of each chemical class of compounds produce virtually identical voltammetric responses. Thus, the full potential is realized when combined with high performance liquid chromatography (HPLC).",WEB:<http://adsabs.harvard.edu/abs/2004SPIE.5261..103L>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01240,,,,,,pulsed amperometric detector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000595,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,pulsed amperometric detector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001259,translational bias design,,A study design that characterizes the association of transcripts and translation machinery.,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,A study design that characterizes the association of transcripts and translation machinery.,MO_939 translational_bias_design,,,,,,translational bias design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000015,,,,,,,,,,,,,,,,OBI:0001259,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,translational bias design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0200176,Fisher's exact test,,"Fisher's exact test is a data transformation used to determine if there are nonrandom associations between two Fisher's exact test is a statistical significance test used in the analysis of contingency tables where sample sizes are small where the significance of the deviation from a null hypothesis can be calculated exactly, rather than relying on an approximation that becomes exact in the limit as the sample size grows to infinity, as with many statistical tests.",false,,,http://purl.obolibrary.org/obo/OBI_0000673,,http://purl.obolibrary.org/obo/OBI_0000675,,,,,,,,,,,,,,,,,"Fisher's exact test is a data transformation used to determine if there are nonrandom associations between two Fisher's exact test is a statistical significance test used in the analysis of contingency tables where sample sizes are small where the significance of the deviation from a null hypothesis can be calculated exactly, rather than relying on an approximation that becomes exact in the limit as the sample size grows to infinity, as with many statistical tests.",WEB:http://mathworld.wolfram.com/FishersExactTest.html,,,,,,Fisher's exact test,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200176,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Fisher's exact test,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/NCBITaxon_39107,Murinae,,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_9989,,,,,,,,,,,,,,,,,,,,,,,,,,Murinae,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:39107,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Murinae,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0002066,detection of specific nucleic acids with complementary probes assay measuring epitope specific granzyme B release by T cells,granzyme B release|RNA/DNA detection,A T cell epitope specific granzyme B release assay that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001436,,,,,,,,,,,,,,,,,,,A T cell epitope specific granzyme B release assay that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific granzyme B release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002066,,,,,,,,,,,,,,,,,,,,,,,,granzyme B release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific granzyme B release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0200042,hierarchical clustering,,"A hierarchical clustering is a data transformation which achieves a class discovery objective, which takes as input data item and builds a hierarchy of clusters. The traditional representation of this hierarchy is a tree (visualized by a dendrogram), with the individual input objects at one end (leaves) and a single cluster containing every object at the other (root).",false,,,http://purl.obolibrary.org/obo/OBI_0200175,,,,,,,,,,,,,,,,,,,"A hierarchical clustering is a data transformation which achieves a class discovery objective, which takes as input data item and builds a hierarchy of clusters. The traditional representation of this hierarchy is a tree (visualized by a dendrogram), with the individual input objects at one end (leaves) and a single cluster containing every object at the other (root).",WEB: http://en.wikipedia.org/wiki/Data_clustering#Hierarchical_clustering,,,,,,hierarchical clustering,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200042,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,hierarchical clustering,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0200174,curve fitting objective,,A curve fitting objective is a data transformation objective in which the aim is to find a curve which matches a series of data points and possibly other constraints.,false,,,http://purl.obolibrary.org/obo/OBI_0200166,,,,,,,,,,,,,,,,,,,A curve fitting objective is a data transformation objective in which the aim is to find a curve which matches a series of data points and possibly other constraints.,PERSON: Elisabetta Manduchi,,,,,,curve fitting objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200174,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,curve fitting objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/IAO_0000178,material information bearer,,A material entity in which a concretization of an information content entity inheres.,false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,A material entity in which a concretization of an information content entity inheres.,,,,,,,material information bearer,,"a brain|A page of a paperback novel with writing on it. The paper itself is a material information bearer, the pattern of ink is the information carrier.|a hard drive",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000178,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,material information bearer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP: IAO,,
http://purl.obolibrary.org/obo/OBI_0001493,cell bound MHC competitive binding assay of a MHC:ligand complex using T cell epitope recognition,qualitative binding|cellular MHC/T cell inhibition,A cell bound MHC binding assay that uses a T cell epitope recognition assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001550,,,,,,,,,,,,,,,,,,,A cell bound MHC binding assay that uses a T cell epitope recognition assay.,IEDB,,,,,,cell bound MHC competitive binding assay of a MHC:ligand complex using T cell epitope recognition,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_1110037,,,,,,,,,,,,,,,,OBI:0001493,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|cellular MHC/T cell inhibition,,,,,,,,,,,,,,,,,,,,,,cell bound MHC competitive binding assay of a MHC:ligand complex using T cell epitope recognition,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/CHEBI_17709,5'-adenylyl sulfate,,An adenosine 5'-phosphate having a sulfo group attached to one the phosphate OH groups.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,An adenosine 5'-phosphate having a sulfo group attached to one the phosphate OH groups.,,,,,,,5'-adenylyl sulfate,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:17709,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,5'-adenylyl sulfate,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0100056,obsolete_immortal cell line culture,immortal cell line sample|permanent cell line,A cell line that is expected to be capable of indefinite propagation in an vitro culture.,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,immortal cell line sample|permanent cell line,,,,,,,,,,,,,,,A cell line that is expected to be capable of indefinite propagation in an vitro culture.,PERSON:Matthew Brush,,,,,"2013-08-09 MHB: Replaced with cell line class from CLO, follwoing outcome of Spring 2013 CLO alignment work.  Subclass axioms were: 'has grain' some 'immortal cell line cell' and 'has grain' only 'immortalcell line cell'

MHB 3-5-13:  This OBI class was formerly called 'immortalized cell line culture', but label changed and definition updated following CLO alignment work in spring of 2013.",obsolete_immortal cell line culture,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000228,,,,,,,,,,,,,,,,,,OBI:0100056,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_immortal cell line culture,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Matthew Brush,http://purl.obolibrary.org/obo/CLO_0009828,
http://purl.obolibrary.org/obo/OBI_0000845,primary structure of RNA molecule,,The primary structure of an RNA molecule that is completely defined by the set of its nucleic residue parts and the linear order induced by the peptide bonds that hold them together,false,,,http://purl.obolibrary.org/obo/SO_0000001,,,,,,,,,,,,,,,,,,,The primary structure of an RNA molecule that is completely defined by the set of its nucleic residue parts and the linear order induced by the peptide bonds that hold them together,,,,,,,primary structure of RNA molecule,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000845,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,primary structure of RNA molecule,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001689,cytochalasin-induced inhibition of actin polymerization assay,,is an assay which uses compound cytochalasin (CHEBI: 23528)  to block actin polymerization-dependent cell motility (GO:0070358) and actin filament polymerization (GO:0030041).,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,add ;actin filament polymerization obo:GO:0070358;,,is an assay which uses compound cytochalasin (CHEBI: 23528)  to block actin polymerization-dependent cell motility (GO:0070358) and actin filament polymerization (GO:0030041).,,,,,,,cytochalasin-induced inhibition of actin polymerization assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001689,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cytochalasin-induced inhibition of actin polymerization assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra; Marcus Chibucos,,
http://purl.obolibrary.org/obo/OBI_0001720,B cell epitope specific immune complex formation,,immune complex formation resulting from antibody binding to epitope,false,,,http://purl.obolibrary.org/obo/GO_0097281|http://purl.obolibrary.org/obo/OBI_0001702,,,,,,,,,,,,,,,,,Date: 2012-05-03; Spreadsheet: BcellAssays.xls; Worksheet: Especific template; Mapping: ebcell_specific_mappings.owl,,immune complex formation resulting from antibody binding to epitope,IEDB (QTT),,,,,,B cell epitope specific immune complex formation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001720,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,B cell epitope specific immune complex formation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000959,vibrotome,,"A preparation device that uses a vibrating razor blade to cut
through tissue.",false,,,http://purl.obolibrary.org/obo/OBI_0000932,,,,,,,,,,,,,,,,,,,"A preparation device that uses a vibrating razor blade to cut
through tissue.",,,,,,,vibrotome,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000372,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000959,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,vibrotome,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001736,RIA measuring the association constant [KA] of a B cell epitope:antibody complex,association constant KA|radio immuno assay (RIA)|1/nM,A B cell epitope equilibrium association constant (KA) determination assay that uses a radio immuno assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001719|http://purl.obolibrary.org/obo/OBI_0001491,,,,,,,,,,,,,,,,,,,A B cell epitope equilibrium association constant (KA) determination assay that uses a radio immuno assay.,IEDB,,,,,,RIA measuring the association constant [KA] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001736,,,,,,,,,,,,,,,,,,,,,,,,association constant KA|radio immuno assay (RIA)|1/nM,,,,,,,,,,,,,,,,,,,,,,RIA measuring the association constant [KA] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/NCBITaxon_7742,Vertebrata <Metazoa>,vertebrates|Vertebrata,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_33213,,,,vertebrates|Vertebrata,,,,,,,,,,,,,,,,,,,,,,Vertebrata <Metazoa>,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:7742,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Vertebrata <Metazoa>,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0042611,MHC protein complex,,"A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen.",false,,,http://purl.obolibrary.org/obo/GO_0043234,,,,,,,,,,,,,,,,,,,"A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen.",,,,,,,MHC protein complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0042611,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,MHC protein complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001335,microRNA profiling by array assay,,An assay in which a microRNA array is used to analyse the microRNA component of the transcriptome.,false,,,http://purl.obolibrary.org/obo/OBI_0001926,,http://purl.obolibrary.org/obo/OBI_0001331,,,,,,,,,,,,,,,,,An assay in which a microRNA array is used to analyse the microRNA component of the transcriptome.,EFO_0000753 microRNA profiling by array,,,,,,microRNA profiling by array assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0400148,,,,,,,,,,,,,,,OBI:0001335,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,microRNA profiling by array assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: James Malone,,
http://purl.obolibrary.org/obo/OBI_0300310,sequential design,,"Any design in which the decision as to whether to enroll the next patient, pair of patients, or block of patients is determined by whether the cumulative treatment difference for all previous patients is within specified limits.  Enrollment is continued if the difference does not exceed the limits.  It is terminated if it does",false,,,http://purl.obolibrary.org/obo/OBI_0000115,,,,,,,,,,,,,,,,,Provenance: OCI,,"Any design in which the decision as to whether to enroll the next patient, pair of patients, or block of patients is determined by whether the cumulative treatment difference for all previous patients is within specified limits.  Enrollment is continued if the difference does not exceed the limits.  It is terminated if it does",MUSC,,,,,,sequential design,,PMID: 17710740.Pharm Stat. 2007 Aug 20.Sequential design approaches for bioequivalence studies with crossover designs.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0300310,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sequential design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_1110061,exposure resulting in immune reactivity,,"a process in which an organism (host) is exposed to some material entity, which results in an immune reactivity",false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,"a process in which an organism (host) is exposed to some material entity, which results in an immune reactivity",IEDB,,,,,,exposure resulting in immune reactivity,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110061,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,exposure resulting in immune reactivity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001289,cytometric bead array assay measuring epitope specific interleukin-5 production by T cells,IL-5 release|cytometric bead array,An assay of epitope specific interleukin-5 production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001230,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-5 production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific interleukin-5 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001289,,,,,,,,,,,,,,,,,,,,,,,,IL-5 release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific interleukin-5 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/GO_0002507,tolerance induction,,"A process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it.",false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,"A process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it.",,,,,,,tolerance induction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0002507,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,tolerance induction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000707,decision tree building data transformation,,A decision tree building data transformation is a data transformation that has objective decision tree induction.,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,A decision tree building data transformation is a data transformation that has objective decision tree induction.,PERSON: James Malone,,,,,,decision tree building data transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000707,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,decision tree building data transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/IAO_0000318,results section,,A part of a publication about an investigation that is about a study design execution,false,,,http://purl.obolibrary.org/obo/IAO_0000314,,,,,,,,,,,,,,,,,,,A part of a publication about an investigation that is about a study design execution,,,,,,,results section,,The section labelled 'results' in a typical scientific journal article,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000318,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000471,,,,,,,,,,,,,,,,results section,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0600039,artificially induced methylation,,A planned process of adding methyl groups to polymers,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,A planned process of adding methyl groups to polymers,OBI branch derived,,,,,,artificially induced methylation,,the use of enzymes to add methyl groups to DNA molecules,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600039,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,artificially induced methylation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Kevin Clancy,,
http://purl.obolibrary.org/obo/OBI_0001126,digital microscope,,A microscope that uses optics and a charge-coupled device (CCD) camera to output a digital image to a monitor.,false,,,http://purl.obolibrary.org/obo/OBI_0400169,,,,,,,,,,,,,,,,,,,A microscope that uses optics and a charge-coupled device (CCD) camera to output a digital image to a monitor.,http://en.wikipedia.org/wiki/Digital_microscope,,,,,,digital microscope,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001126,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,digital microscope,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0000576,scattered molecular aggregate,Collective,a material entity that consists of all the molecules of a specific type that are located in some bounded region and which is part of a more massive material entity that has parts that are other such aggregates,false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,Collective,,,,,,,,,,,,,,,a material entity that consists of all the molecules of a specific type that are located in some bounded region and which is part of a more massive material entity that has parts that are other such aggregates,"Discussion in Karslruhe with, among others, Alan Rector, Stefan Schulz, Marijke Keet, Melanie Courtot, and Alan Ruttenberg. With inspiration from the paper Granularity, scale and collectivity: When size does and does not matter, Alan Recto, Jeremy Rogers, Thomas Bittner, Journal of Biomedical Informatics 39 (2006) 333-349",,,,,,scattered molecular aggregate,,the sodium and chloride ions in a glass of salt water,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000576,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,scattered molecular aggregate,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0400007,analog-to-digital converter,A-D|A2D,An analog-to-digital_converter is an instrument that converts an infinite resolution analog signal to a finite resolution digital signal.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,A-D|A2D,,,,,,,,,,,,,,,An analog-to-digital_converter is an instrument that converts an infinite resolution analog signal to a finite resolution digital signal.,http://en.wiktionary.org/wiki/Analog-to-Digital_Converter,,,,,,analog-to-digital converter,,The analog to digital converter transformed the analog output from the photomultiplier tube to a digital signal for collection.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000393,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400007,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,analog-to-digital converter,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Melanie Courtot|John Quinn,,
http://purl.obolibrary.org/obo/OBI_0001449,biological activity assay measuring epitope specific interleukin-1 beta production by T cells,IL-1b release|biological activity,A T cell epitope specific cytokine production assay that detects interleukin-1 beta production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects interleukin-1 beta production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific interleukin-1 beta production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001449,,,,,,,,,,,,,,,,,,,,,,,,IL-1b release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific interleukin-1 beta production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000880,RNA extract,,an extract which is the output of an extraction process in which RNA molecules are isolated from a specimen.,false,,,http://purl.obolibrary.org/obo/OBI_0001010,,,,,,,,,,,,,,,,,,,an extract which is the output of an extraction process in which RNA molecules are isolated from a specimen.,Group: UPenn Group,,,,,,RNA extract,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,http://purl.obolibrary.org/obo/CHEBI_33697,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000880,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0666666,,,RNA extract,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Chris Stoeckert|PERSON: Jie Zheng,,
http://purl.obolibrary.org/obo/OBI_1110153,ELISA measuring epitope specific interleukin-4 production by T cells,IL-4 release|ELISA,An assay of epitope specific interleukin-4 production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001450,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-4 production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific interleukin-4 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110153,,,,,,,,,,,,,,,,,,,,,,,,IL-4 release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific interleukin-4 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/IAO_0000328,table of figures,,A table that relates figures in a document to specific locations in that document (usually page numbers).  This is also a document part (subsumption there should be inferred).,false,,,http://purl.obolibrary.org/obo/IAO_0000306,,,,,,,,,,,,,,,,,,,A table that relates figures in a document to specific locations in that document (usually page numbers).  This is also a document part (subsumption there should be inferred).,,,,,,,table of figures,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000328,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,table of figures,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Lawrence Hunter,,
http://purl.obolibrary.org/obo/OBI_0000983,intranasal mucosal administration,,The administration of a substance into the intranasal mucosis of an organism,false,,,http://purl.obolibrary.org/obo/OBI_0600007,,http://purl.obolibrary.org/obo/OBI_0000434,,,,,,,,,,,,,,,,,The administration of a substance into the intranasal mucosis of an organism,,,,,,,intranasal mucosal administration,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000983,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,intranasal mucosal administration,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0002062,in vitro assay measuring epitope specific T cell killing,cytotoxicity|in vitro assay,A T cell epitope specific killing assay that uses an in vitro cell killing assay.,false,,,http://purl.obolibrary.org/obo/OBI_1110130,,,,,,,,,,,,,,,,,,,A T cell epitope specific killing assay that uses an in vitro cell killing assay.,IEDB,,,,,,in vitro assay measuring epitope specific T cell killing,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002062,,,,,,,,,,,,,,,,,,,,,,,,cytotoxicity|in vitro assay,,,,,,,,,,,,,,,,,,,,,,in vitro assay measuring epitope specific T cell killing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001992,assay measuring the half maximal inhibitory concentration [IC50] of a MHC:ligand complex,half maximal inhibitory concentration (IC50)|binding assay|nM,A MHC binding constant determination assay measuring half maximal inhibitory concentration (IC50).,false,,,http://purl.obolibrary.org/obo/OBI_0001553,,,,,,,,,,,,,,,,,,,A MHC binding constant determination assay measuring half maximal inhibitory concentration (IC50).,IEDB,,,,,,assay measuring the half maximal inhibitory concentration [IC50] of a MHC:ligand complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001992,,,,,,,,,,,,,,,,,,,,,,,,half maximal inhibitory concentration (IC50)|binding assay|nM,,,,,,,,,,,,,,,,,,,,,,assay measuring the half maximal inhibitory concentration [IC50] of a MHC:ligand complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://www.geneontology.org/formats/oboInOwl#DbXref,DbXref,,,false,,,http://purl.obolibrary.org/obo/IAO_0000102,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,oboInOwl:DbXref,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000709,yeast artificial chromosome vector,YAC,"a double-stranded DNA that was engineered to contain a yeast origin of replication, encodes for a selectable gene product, contains a cloning site, and has yeast telomerase sequences",false,,,http://purl.obolibrary.org/obo/OBI_0000737|http://purl.obolibrary.org/obo/CHEBI_4705,,,,YAC,,,,,,,,,,,,,,,"a double-stranded DNA that was engineered to contain a yeast origin of replication, encodes for a selectable gene product, contains a cloning site, and has yeast telomerase sequences",,,,,,this should be a child of 'chromosome' if we import that from another source,yeast artificial chromosome vector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000411,,,,,,,,,,,,OBI:0000709,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,yeast artificial chromosome vector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Kevin Clancy, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_1110029,C1R cell line,,A cell line derived from human B cells. This cell line was created by EBV transformation (B-lymphoblastoid cell-line (BLCL)).,false,,,http://purl.obolibrary.org/obo/CLO_0009828,,,,,,,,,,,,,,,,,,,A cell line derived from human B cells. This cell line was created by EBV transformation (B-lymphoblastoid cell-line (BLCL)).,IEDB,,,,,,C1R cell line,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110029,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,C1R cell line,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/PATO_0001385,aneuploid,,"A ploidy quality inhering in a bearer by virtue of the bearer's containing a non-integral multiple of the monoploid number, due to extra or missing chromosomes.",false,,,http://purl.obolibrary.org/obo/PATO_0001374,,,,,,,,,,,,,,,,,,,"A ploidy quality inhering in a bearer by virtue of the bearer's containing a non-integral multiple of the monoploid number, due to extra or missing chromosomes.",,,,,,,aneuploid,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001385,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,aneuploid,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000941,service consumer role,,a role which inheres in a person who uses a service,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,,,a role which inheres in a person who uses a service,OBI,,,,,,service consumer role,,A biologist who uses a sequencing services fulfills the role of a service consumer,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000941,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,service consumer role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Helen Parkinson,,
http://purl.obolibrary.org/obo/PATO_0001375,haploid,,A ploidy quality inhering in a bearer by virtue of the bearer's containing a single set of homologous chromosomes.,false,,,http://purl.obolibrary.org/obo/PATO_0001374,,,,,,,,,,,,,,,,,,,A ploidy quality inhering in a bearer by virtue of the bearer's containing a single set of homologous chromosomes.,,,,,,,haploid,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001375,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,haploid,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0001377,polyploid,,A ploidy quality inhering in a bearer by virtue of the bearer's containing more than two homologous sets of chromosomes.,false,,,http://purl.obolibrary.org/obo/PATO_0001374,,,,,,,,,,,,,,,,,,,A ploidy quality inhering in a bearer by virtue of the bearer's containing more than two homologous sets of chromosomes.,,,,,,,polyploid,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001377,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,polyploid,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0001374,ploidy,,"A cellular quality inhering in a bearer by virtue of the bearer's number of homologous sets of chromosomes in the nucleus or primary chromosome-containing compartment of the cell, each set essentially coding for all the biological traits of the organism.",false,,,http://purl.obolibrary.org/obo/PATO_0001396,,,,,,,,,,,,,,,,,,,"A cellular quality inhering in a bearer by virtue of the bearer's number of homologous sets of chromosomes in the nucleus or primary chromosome-containing compartment of the cell, each set essentially coding for all the biological traits of the organism.",,,,,,,ploidy,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001374,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,ploidy,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000517,NMR magnet,,A magnet which induces a certain frequency (MHz) and which has a certain bore diameter.\n  alt The NMR signal is a natural physical property of the certain atomic nuclei but it can only be detected with an external magnetic field. A magnet is a fundamental part of an NMR instrument which induces an electromagnetic force field (RF pulse) and by this excites and aligns the spins of the electrons of the NMR acquisition nucleus. It is usually a big (superconducting) electromagnet which is cooled by liquid helium and can be adjusted to a frequency between 200 and 950 MHz. The magnetic field strength is measured in Tesla or Gauss.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,NMR instrument,,A magnet which induces a certain frequency (MHz) and which has a certain bore diameter.\n  alt The NMR signal is a natural physical property of the certain atomic nuclei but it can only be detected with an external magnetic field. A magnet is a fundamental part of an NMR instrument which induces an electromagnetic force field (RF pulse) and by this excites and aligns the spins of the electrons of the NMR acquisition nucleus. It is usually a big (superconducting) electromagnet which is cooled by liquid helium and can be adjusted to a frequency between 200 and 950 MHz. The magnetic field strength is measured in Tesla or Gauss.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400185,,,,,,NMR magnet,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000517,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NMR magnet,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000486,continuous wave NMR instrument,,"Continuous wave NMR spectrometers are similar to optical spectrometers, but the sample is held in a strong magnetic field, where the frequency of the source is slowly scanned (in some instruments, the source frequency is held constant, and the field is scanned).",false,,,http://purl.obolibrary.org/obo/OBI_0000566,,,,,,,,,,,,,,,,,NMR instrument,,"Continuous wave NMR spectrometers are similar to optical spectrometers, but the sample is held in a strong magnetic field, where the frequency of the source is slowly scanned (in some instruments, the source frequency is held constant, and the field is scanned).",WEB:<http://teaching.shu.ac.uk/hwb/chemistry/tutorials/molspec/nmr3.htm>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400283,,,,,,continuous wave NMR instrument,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000486,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,continuous wave NMR instrument,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0200074,submatrix extraction,,"A submatrix extraction is a projection whose input is a matrix and whose output is a matrix obtained by selecting certain rows and columns from the input. (Note that, if one represents the input matrix as a vector obtained by concatenating its rows, then extracting a submatrix is equivalent to projecting this vector into that composed by the entries belonging to the rows and columns of interest from the input matrix.)",false,,,http://purl.obolibrary.org/obo/OBI_0200050,,,,,,,,,,,,,,,,,,,"A submatrix extraction is a projection whose input is a matrix and whose output is a matrix obtained by selecting certain rows and columns from the input. (Note that, if one represents the input matrix as a vector obtained by concatenating its rows, then extracting a submatrix is equivalent to projecting this vector into that composed by the entries belonging to the rows and columns of interest from the input matrix.)",WEB: http://en.wikipedia.org/wiki/Submatrix,,,,,Note that this can be considered as a special case of projection if one represents the input matrix as a vector obtained by concatenating its rows. Then extracting a submatrix is equivalent to projecting this vector into the entries belonging to the rows and columns of interest from the input matrix.,submatrix extraction,,"When presented with the data from an expression microarray experiment in the form of a matrix, whose rows correspond to genes and whose columns correspond to samples, if one filters some of the genes and/or some of the samples out, the resulting data set corresponds to a submatrix of the original set.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200074,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,submatrix extraction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Melanie Courtot|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/IAO_0000144,conclusion textual entity,,"A textual entity that expresses the results of reasoning about a problem, for instance as typically found towards the end of scientific papers.",false,,,http://purl.obolibrary.org/obo/OBI_0001909|http://purl.obolibrary.org/obo/IAO_0000300,,,,,,,,,,,,,,,,,,,"A textual entity that expresses the results of reasoning about a problem, for instance as typically found towards the end of scientific papers.",,,,,,2009/10/23 Alan Ruttenberg: We need to work on the definition still|2009/09/28 Alan Ruttenberg. Fucoidan-use-case,conclusion textual entity,,"that fucoidan has a small statistically significant effect on AT3 level but no useful clinical effect as in-vivo anticoagulant, a paraphrase of part of the last paragraph of the discussion section of the paper 'Pilot clinical study to evaluate the anticoagulant activity of fucoidan', by Lowenthal et. al.PMID:19696660",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000144,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000338,http://purl.obolibrary.org/obo/IAO_0000027,,conclusion textual entity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0001982,protection from challenge in vivo intervention experiment,,An in vivo intervention experiment that tests the ability of the intervention to prevent occurrence of a disease in a host.,false,,,http://purl.obolibrary.org/obo/OBI_0001980,,,,,,,,,,,,,,,,,,,An in vivo intervention experiment that tests the ability of the intervention to prevent occurrence of a disease in a host.,IEDB,,,,,should have challenge as intervention ,protection from challenge in vivo intervention experiment,,Injecting a set of mice with a peptide and measuring symtoms to determine if their disease course was less severe than the disease course of a set of mice that were not injected with the same peptide. ,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001982,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,protection from challenge in vivo intervention experiment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000474,nano pump system,,A pump system optimized for nano flow chromatography.,false,,,http://purl.obolibrary.org/obo/OBI_0000589,,,,,,,,,,,,,,,,,,,A pump system optimized for nano flow chromatography.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01052,,,,,,nano pump system,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000474,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,nano pump system,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_1110161,ELISA measuring epitope specific interleukin-1 beta production by T cells,IL-1b release|ELISA,An assay of epitope specific interleukin-1 beta production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001449,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-1 beta production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific interleukin-1 beta production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110161,,,,,,,,,,,,,,,,,,,,,,,,IL-1b release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific interleukin-1 beta production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/CHEBI_25078,luciferin,,A low-molecular-mass compound present in bioluminescent organisms that emits light when oxidized in presence of enzyme luciferase.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,A low-molecular-mass compound present in bioluminescent organisms that emits light when oxidized in presence of enzyme luciferase.,,,,,,,luciferin,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:25078,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,luciferin,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001931,scalar value specification,,A value specification that consists of two parts: a numeral and a unit label,false,,,http://purl.obolibrary.org/obo/OBI_0001933,,,,,,,,,,,,,,,,,,,A value specification that consists of two parts: a numeral and a unit label,,,,,,,scalar value specification,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001931,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,scalar value specification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000925,infectious agent,,is a material entity bearing the disposition to infect an organism,false,,,http://purl.obolibrary.org/obo/OBI_0100026,,,,,,,,,,,,,,,,,,,is a material entity bearing the disposition to infect an organism,IEDB,,,,,,infectious agent,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000925,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,infectious agent,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0002017,histone modification identification by ChIP-Seq assay,histone modification ChIP-Seq,A ChIP-seq assay to identify regions containing specific histones and their modifications.,false,,,http://purl.obolibrary.org/obo/OBI_0000716,,http://purl.obolibrary.org/obo/OBI_0001234,,histone modification ChIP-Seq,,,,,,,,,,,,,,,A ChIP-seq assay to identify regions containing specific histones and their modifications.,Penn group,,,,,,histone modification identification by ChIP-Seq assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002017,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,histone modification identification by ChIP-Seq assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Beta Cell Biology Consoritum,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0400038,FACS Canto2,,"A FACS_Canto2 is a flow_cytometer_analyser manufactured by BD. It features digital electronics, two solid state lasers at 488 and 633 nm with the option for a third 405 nm laser, and filters and collectors for measuring up to 8 fluorescent paramters with either the 2 or 3 laser option. The FACS_Canto2 is an analyser usually used in clinical applications.",false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,,,,,,,,,,,,,,,,"A FACS_Canto2 is a flow_cytometer_analyser manufactured by BD. It features digital electronics, two solid state lasers at 488 and 633 nm with the option for a third 405 nm laser, and filters and collectors for measuring up to 8 fluorescent paramters with either the 2 or 3 laser option. The FACS_Canto2 is an analyser usually used in clinical applications.",http://www.bdbiosciences.com/cgi-bin/literature/view?part_num=23-8786-01,,,,,,FACS Canto2,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400038,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,FACS Canto2,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0001481,lowess global transformation,,"A lowess transformation where the same normalization curve is used for all members of the data set; e.g. Features on an array, picked spots on a gel, or measured metabolites in a sample. ",false,,,http://purl.obolibrary.org/obo/OBI_0001477,,,,,,,,,,,,,,,,,,,"A lowess transformation where the same normalization curve is used for all members of the data set; e.g. Features on an array, picked spots on a gel, or measured metabolites in a sample. ",MO_692 lowess_global_normalization,,,,,,lowess global transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001481,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,lowess global transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0000494,liquid chromatography autosampler,,Designed to perform capillary LC with injection of sample volumes ranging from nL to L.,false,,,http://purl.obolibrary.org/obo/OBI_0000485,,,,,,,,,,,,,,,,,,,Designed to perform capillary LC with injection of sample volumes ranging from nL to L.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01061,,,,,,liquid chromatography autosampler,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000494,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,liquid chromatography autosampler,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0200091,inter-rater reliability objective,inter-rater agreement,a data transformation objective of determining the concordance or agreement between human judges.,false,,,http://purl.obolibrary.org/obo/OBI_0200166,,,,inter-rater agreement,,,,,,,,,,,,,,,a data transformation objective of determining the concordance or agreement between human judges.,http://en.wikipedia.org/wiki/Inter-rater_reliability,,,,,,inter-rater reliability objective,,"A study was conducted to determine the inter-rater reliability of common clinical examination procedures proposed to identify patients with lumbar segmental instability.

Examples include joint-probability of agreement, Cohen's kappa and the related Fleiss' kappa, inter-rater correlation, concordance correlation coefficient and intra-class correlation.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200091,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,inter-rater reliability objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Helen Parkinson|Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0001699,antibody cross-blocking assay,antibody inhibition of antibody binding,"A competitive inhibition of binding assay in which two antibodies that are known to bind the same antigen are tested for the ability of one antibody to inhibit binding of the other antibody to the antigen, thereby determining if they have overlapping binding sites.",false,,,http://purl.obolibrary.org/obo/OBI_0001593,,,,antibody inhibition of antibody binding,,,,,,,,,,,,,,,"A competitive inhibition of binding assay in which two antibodies that are known to bind the same antigen are tested for the ability of one antibody to inhibit binding of the other antibody to the antigen, thereby determining if they have overlapping binding sites.",IEDB,,,,,,antibody cross-blocking assay,,Testing two antibodies that bind the HBV core protein for the ability of one antibody pre-incubated with the protein in solution to inhibit binding to the other antibody which is plate-bound in an ELISA format.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001699,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,antibody cross-blocking assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0002061,cytometric bead array assay measuring epitope specific chemokine (C-C motif) ligand 22 production by T cells,CCL22/MDC release|cytometric bead array,An assay of epitope specific chemokine (C-C motif) ligand 22 production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001777,,,,,,,,,,,,,,,,,,,An assay of epitope specific chemokine (C-C motif) ligand 22 production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific chemokine (C-C motif) ligand 22 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002061,,,,,,,,,,,,,,,,,,,,,,,,CCL22/MDC release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific chemokine (C-C motif) ligand 22 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0002030,genotyping by tiling array,DNA sequence variation detection by tiling array,"A genotyping by array assay that aims to detect variation in (mostly) genomic DNA of an organism, strain, etc relative to some reference sequence employing tiling array technology.",false,,,http://purl.obolibrary.org/obo/OBI_0001274,,,,DNA sequence variation detection by tiling array,,,,,,,,,,,,,,,"A genotyping by array assay that aims to detect variation in (mostly) genomic DNA of an organism, strain, etc relative to some reference sequence employing tiling array technology.",PMID:19521816,,,,,Details see tracker: https://sourceforge.net/p/obi/obi-terms/720/,genotyping by tiling array,,PMID:19521816,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001307,,,,,,,,,,,,,,,OBI:0002030,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,genotyping by tiling array,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Saccharomyces Genome Database (SGD),,,,,,,,"Person:Janos Demeter, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0002067,cytometric bead array assay measuring epitope specific macrophage migration inhibitory factor (MIF) production by T cells,MIF release|cytometric bead array,An assay of epitope specific macrophage migration inhibitory factor (MIF) production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0002057,,,,,,,,,,,,,,,,,,,An assay of epitope specific macrophage migration inhibitory factor (MIF) production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific macrophage migration inhibitory factor (MIF) production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002067,,,,,,,,,,,,,,,,,,,,,,,,MIF release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific macrophage migration inhibitory factor (MIF) production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0200098,soft independent modeling of class analogy analysis,SIMCA,Soft independent modeling by class analogy (SIMCA) is a descriptive statistics method for supervised classification of data. The method requires a training data set consisting of samples (or objects) with a set of attributes and their class membership. The term soft refers to the fact the classifier can identify samples as belonging to multiple classes and not necessarily producing a classification of samples into non-overlapping classes.,false,,,http://purl.obolibrary.org/obo/OBI_0200169,,http://purl.obolibrary.org/obo/OBI_0200167,,SIMCA,,,,,,,,,,,,,,,Soft independent modeling by class analogy (SIMCA) is a descriptive statistics method for supervised classification of data. The method requires a training data set consisting of samples (or objects) with a set of attributes and their class membership. The term soft refers to the fact the classifier can identify samples as belonging to multiple classes and not necessarily producing a classification of samples into non-overlapping classes.,WEB: http://en.wikipedia.org/wiki/Soft_independent_modelling_of_class_analogies,,,,,,soft independent modeling of class analogy analysis,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200098,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,soft independent modeling of class analogy analysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Tina Hernandez-Boussard,,
http://purl.obolibrary.org/obo/OGMS_0000063,disease course,,The totality of all processes through which a given disease instance is realized.,false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,"replace 'OBI:occurrence of disease', need to add logical definition
The axioms of OBI occurence of disease:
Equivalent classes:
realizes some disease
Superclasses:
'has part' some 'pathologic process'
'has participant' some 
    (organism
     and ('has role' some 'host of immune response role'))
biological_process
realizes some 'host of immune response role'",,The totality of all processes through which a given disease instance is realized.,,,,,,,disease course,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OGMS:0000063,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ogms.owl,,,,,,,,,,,,,,,,,,,disease course,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001156,age since planting measurement datum,,"An age measurement datum that is the result of the measurement of the age of an organism since planting, the process of placing a plant in media (e.g. soil) to allow it to grow, which excludes sowing.",false,,,http://purl.obolibrary.org/obo/OBI_0001167,,,,,,,,,,,,,,,,,"Discussed by Jie and Chris, proposed to combine with different kinds of processes as initial time point. Proposed 'age measurement assay' is proceeded by some process. The process can be any kind of process defined in OBI. Think it is more flexible. However, it is hard to model  due to lake of temporal predicates on Nov 15, 2010 dev call.
Term proposed by Bjoern on Nov 8, 2010 dev call
Supported by Alan on Nov 15, 2010 dev call",,"An age measurement datum that is the result of the measurement of the age of an organism since planting, the process of placing a plant in media (e.g. soil) to allow it to grow, which excludes sowing.",MO_495 planting,,,,,,age since planting measurement datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001156,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,age since planting measurement datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001867,establishing cell line,,"a process whereby a new type of cell line is created, either through passaging of a primary cell culture to relative genetic stability and compositional homogeneity, or through some experimental modification of an existing cell line to produce a new line with novel characteristics  (e.g. immortalization or some other stable genetic modification, or selection of some defined subset).",false,,,http://purl.obolibrary.org/obo/OBI_0600036,,,,,,,,,,,,,,,,,,,"a process whereby a new type of cell line is created, either through passaging of a primary cell culture to relative genetic stability and compositional homogeneity, or through some experimental modification of an existing cell line to produce a new line with novel characteristics  (e.g. immortalization or some other stable genetic modification, or selection of some defined subset).",PERSON:Matthew Brush,,,,,"2013-4-20 MHB: For cases of initial establilshment of a line from a primary culture, successive passaging and/or selection processes can confer increasing degrees of genetic stability and compositional homogeneity as compared to the input primary culture. Historically, many texts consider the first passage as the clearest point to define the beginning of a line. However, in practice it is more often that case that more than one passage, and possibly additional selective techniques, may be required before a culture is deemed to have sufficient stability and homogeneity to be considered cell line. This is the view taken in OBI. Regardless, what is important is that some intentional, experimental step has been taken to establish a more homogenous and stable culture that can be characterized and  progatated over time.",establishing cell line,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CLO_0000031,,,OBI:0001867,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,establishing cell line,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_0001313,transcription profiling by RT-PCR design,,A study design which aims to examine the transcriptome of a biological sample by reverse transcription PCR (RT-PCR).,false,,,http://purl.obolibrary.org/obo/OBI_0001430,,,,,,,,,,,,,,,,,,,A study design which aims to examine the transcriptome of a biological sample by reverse transcription PCR (RT-PCR).,Group: ArrayExpress production team,,,,,,transcription profiling by RT-PCR design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001331,,,,,,,,,,,,,,,,OBI:0001313,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,transcription profiling by RT-PCR design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000625,JEOL ECX NMR spectrometer,,"The ECX series of NMR spectrometers is designed for any laboratory needing an easy-to-use, reliable, routine NMR system. The ECX NMR series is available from 300 to 500 MHz. The console is designed around a modular, digital NMR electronics chassis controlled by an intelligent acquisition computer. For unprecedented flexibility, the JEOL NMR system offers a Windows XP, Mac OSX or LINUX. Both the workstation and spectrometer may be connected to a standard network, allowing seamless remote operation anywhere in the world.",false,,,http://purl.obolibrary.org/obo/OBI_0000600,,,,,,,,,,,,,,,,,NMR instrument,,"The ECX series of NMR spectrometers is designed for any laboratory needing an easy-to-use, reliable, routine NMR system. The ECX NMR series is available from 300 to 500 MHz. The console is designed around a modular, digital NMR electronics chassis controlled by an intelligent acquisition computer. For unprecedented flexibility, the JEOL NMR system offers a Windows XP, Mac OSX or LINUX. Both the workstation and spectrometer may be connected to a standard network, allowing seamless remote operation anywhere in the world.",WEB:<http://www.jeol.com/PRODUCTS/AnalyticalInstruments/NuclearMagneticResonance/ECX/tabid/145/Default.aspx>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400227,,,,,,JEOL ECX NMR spectrometer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000625,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,JEOL ECX NMR spectrometer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/GO_0032615,interleukin-12 production,,"The appearance of interleukin-12 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-12 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-12 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032615,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-12 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032613,interleukin-10 production,,"The appearance of interleukin-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-10 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032613,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-10 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032610,interleukin-1 alpha production,,"The appearance of interleukin-1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0032612,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-1 alpha production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032610,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-1 alpha production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032618,interleukin-15 production,,"The appearance of interleukin-15 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-15 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-15 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032618,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-15 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032617,interleukin-14 production,,"The appearance of interleukin-14 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-14 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-14 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032617,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-14 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032619,interleukin-16 production,,"The appearance of interleukin-16 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-16 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-16 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032619,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-16 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032611,interleukin-1 beta production,,"The appearance of interleukin-1 beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0032612,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-1 beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-1 beta production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032611,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-1 beta production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032616,interleukin-13 production,,"The appearance of interleukin-13 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-13 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-13 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032616,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-13 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032612,interleukin-1 production,,"The appearance of interleukin-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-1 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032612,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-1 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032614,interleukin-11 production,,"The appearance of interleukin-11 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-11 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-11 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032614,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-11 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001363,biological activity assay measuring epitope specific interleukin-23 production by T cells,IL-23 release|biological activity,A T cell epitope specific cytokine production assay that detects interleukin-23 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects interleukin-23 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific interleukin-23 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001363,,,,,,,,,,,,,,,,,,,,,,,,IL-23 release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific interleukin-23 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0400076,multi-well plate,,A particle deliver vessel. A multi-well plate is a vessel that can deliver multiple samples to a flow cytometer in a specified order. It must be used with a plate loader.,false,,,http://purl.obolibrary.org/obo/OBI_0400081,,,,,,,,,,,,,,,,,,,A particle deliver vessel. A multi-well plate is a vessel that can deliver multiple samples to a flow cytometer in a specified order. It must be used with a plate loader.,http://www.nuncbrand.com/page.aspx?ID=301,,,,,FG this is synonymous with microtiter plate,multi-well plate,,"96 well plate, 48 multiwell plate",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400076,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,multi-well plate,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0000874,detection of specific nucleic acid polymers with complementary probes,,"An analyte assay in which a specified input material (the evaluant) is examined for the presence or quantity of specified nucleic acid polymers, which are identified based on the use of complementary nucleic acid probes.",false,,,http://purl.obolibrary.org/obo/OBI_0000443,,,,,,,,,,,,,,,,,,,"An analyte assay in which a specified input material (the evaluant) is examined for the presence or quantity of specified nucleic acid polymers, which are identified based on the use of complementary nucleic acid probes.",IEDB,,,,,,detection of specific nucleic acid polymers with complementary probes,,"Primer based PCR assay, Norther blot, Southern Blot, and RNAse protection assays.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000874,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acid polymers with complementary probes,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001912,cell freezing medium,,"A processed material that serves as a liquid vehicle for freezing cells for long term quiescent stroage, which contains chemicls needed to sustain cell viability across freeze-thaw cycles. ",false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,,,,,,,,,,,,,,,,"A processed material that serves as a liquid vehicle for freezing cells for long term quiescent stroage, which contains chemicls needed to sustain cell viability across freeze-thaw cycles. ",,,,,,,cell freezing medium,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001912,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cell freezing medium,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_0000718,pathogen role,,pathogen role is a role which inheres in an organism and realized in the process of disease course in the organism bearing host role caused by the organism bearing pathogen role,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,6 April 2009:  from the Vaccine Community,,pathogen role is a role which inheres in an organism and realized in the process of disease course in the organism bearing host role caused by the organism bearing pathogen role,OBI,,,,,,pathogen role,,"Pathogen: An agent of disease. A disease producer. The term pathogen most commonly is used to refer to infectious organisms. These include bacteria (such as staph), viruses (such as HIV), and fungi (such as yeast). Less commonly, pathogen refers to a noninfectious agent of disease such as a chemical.   http://www.medterms.com/script/main/art.asp?articlekey=6383",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000718,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100026,,,,,,,,,,,,,,,,,pathogen role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP: Role Branch,,
http://purl.obolibrary.org/obo/OBI_0000125,number of lost events electronic,,A measurement datum measuring the number of analysis events lost due to errors in data acquisition electronic coincidence in a flow cytometer instrument. The datum has a qualitative role.,false,,,http://purl.obolibrary.org/obo/IAO_0000109,,,,,,,,,,,,,,,,,,,A measurement datum measuring the number of analysis events lost due to errors in data acquisition electronic coincidence in a flow cytometer instrument. The datum has a qualitative role.,Submitted by the Flow Cytometry community in DigitalEntity-FlowCytometry-2007-03-30.txt,,,,,,number of lost events electronic,,"74, 0, 14 events lost due to data acquisition electronic coincidence.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,number of lost events electronic,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Kevin Clancy,,
http://purl.obolibrary.org/obo/OBI_0001163,age since eclosion measurement datum,,"An age measurement datum that is the result of the measurement of the age of an organism since eclosion, the process of emergence of an adult insect from its pupa or cocoon.",false,,,http://purl.obolibrary.org/obo/OBI_0001167,,,,,,,,,,,,,,,,,,,"An age measurement datum that is the result of the measurement of the age of an organism since eclosion, the process of emergence of an adult insect from its pupa or cocoon.",MO_876 eclosion,,,,,,age since eclosion measurement datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001163,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,age since eclosion measurement datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001048,digital camera,,"An image acquisition device that takes video or still photographs, or both, digitally by recording images via an electronic image sensor.",false,,,http://purl.obolibrary.org/obo/OBI_0000398,,,,,,,,,,,,,,,,,,,"An image acquisition device that takes video or still photographs, or both, digitally by recording images via an electronic image sensor.",http://en.wikipedia.org/wiki/Digital_camera,,,,,,digital camera,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000397,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001048,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,digital camera,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0000804,informing investigator of subject study arm,,"A process in which an investigator is made aware of which study arm that a patient is participating in, for example whether they are receiving a placebo or a treatment with an investigational compound.",false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,,,,,,,,,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,,"A process in which an investigator is made aware of which study arm that a patient is participating in, for example whether they are receiving a placebo or a treatment with an investigational compound.",,,,,,"09/28/2009 Alan Ruttenberg. This and the class informing-subject-of-study-arm are defined in order to solve the question of how to represent single and double blind experiments. To represent the aspect of double blinding pertaining to investigators, we say that the study execution doesn't include any processes of this sort",informing investigator of subject study arm,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000804,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,informing investigator of subject study arm,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0001961,PCR program,,"a PCR program is a plan specification which is executed during a polymerase chain reaction (PCR) by a thermocycler instrument that will iterate through the changes in temperature and duration of each of the annealing, denaturation, elongation steps for as many times as specified by the program.",false,,,http://purl.obolibrary.org/obo/IAO_0000104,,,,,,,,,,,,,,,,,,,"a PCR program is a plan specification which is executed during a polymerase chain reaction (PCR) by a thermocycler instrument that will iterate through the changes in temperature and duration of each of the annealing, denaturation, elongation steps for as many times as specified by the program.",OBI,,,,,,PCR program,,https://www.neb.com/protocols/1/01/01/taq-dna-polymerase-with-standard-taq-buffer-m0273,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001961,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PCR program,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/IAO_0000031,integer numeral,,a numeral that denotes an integer,false,,,http://purl.obolibrary.org/obo/IAO_0000029,,,,,,,,,,,,,,,,,,,a numeral that denotes an integer,,,,,,,integer numeral,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000031,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,integer numeral,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Jonathan Rees,,
http://purl.obolibrary.org/obo/BFO_0000035,process boundary,,p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001]),false,,,http://purl.obolibrary.org/obo/BFO_0000003,,,,,,,ProcessBoundary,p-boundary,,,,,,,,,,,p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001]),,,,,,,process boundary,,the boundary between the 2nd and 3rd year of your life.,,,,,,,,(forall (x) (if (ProcessBoundary x) (exists (y) (and (ZeroDimensionalTemporalRegion y) (occupiesTemporalRegion x y))))) // axiom label in BFO2 CLIF: [085-002] |(iff (ProcessBoundary a) (exists (p) (and (Process p) (temporalPartOf a p) (not (exists (b) (properTemporalPartOf b a)))))) // axiom label in BFO2 CLIF: [084-001] ,Every process boundary occupies_temporal_region a zero-dimensional temporal region. (axiom label in BFO2 Reference: [085-002]),,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000035,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,process boundary,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001803,ELISA measuring epitope specific interleukin-7 production by T cells,IL-7 release|ELISA,An assay of epitope specific interleukin-7 production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001587,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-7 production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific interleukin-7 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001803,,,,,,,,,,,,,,,,,,,,,,,,IL-7 release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific interleukin-7 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000059,gamma counter,,A processed material which measures gamma radiation,false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,A processed material which measures gamma radiation,http://en.wikipedia.org/wiki/Gamma_counter,,,,,,gamma counter,,A Geiger counter,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000059,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,gamma counter,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Frank Gibson,,
http://purl.obolibrary.org/obo/OBI_0000982,computed tomography scanner,X-ray computed tomography scanner|CT scanner,"An image acquisition device that generates a
three-dimensional image of the inside of an object from a large series of
two-dimensional X-ray images taken around a single axis of rotation.",false,,,http://purl.obolibrary.org/obo/OBI_0000398,,,,X-ray computed tomography scanner|CT scanner,,,,,,,,,,,,,,,"An image acquisition device that generates a
three-dimensional image of the inside of an object from a large series of
two-dimensional X-ray images taken around a single axis of rotation.",http://en.wikipedia.org/wiki/X-ray_computed_tomography,,,,,,computed tomography scanner,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000397,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000982,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,computed tomography scanner,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001127,freeze substitution system,,A device or system for dehydrating and then chemically fixing electron microscopy samples at low temperatures in preparation for various treatments including embedding in resins.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A device or system for dehydrating and then chemically fixing electron microscopy samples at low temperatures in preparation for various treatments including embedding in resins.,doi:10.1017/S143192760707866X,,,,,,freeze substitution system,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000379|http://purl.obolibrary.org/obo/OBI_0000375,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001127,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,freeze substitution system,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001196,cytometric bead array assay measuring epitope specific IP-10 production by T cells,CXCL10/IP-10 release|cytometric bead array,An assay of epitope specific IP-10 production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001308,,,,,,,,,,,,,,,,,,,An assay of epitope specific IP-10 production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific IP-10 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001196,,,,,,,,,,,,,,,,,,,,,,,,CXCL10/IP-10 release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific IP-10 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/NCBITaxon_4932,Saccharomyces cerevisiae,lager beer yeast|baker's yeast|brewer's yeast|yeast,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_716545,,,,lager beer yeast|baker's yeast|brewer's yeast|yeast,,,,,,,,,,,,,,,,,,,,,,Saccharomyces cerevisiae,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:4932,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Saccharomyces cerevisiae,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200102,regression analysis method,,Regression analysis is a descriptive statistics technique that examines the relation of a dependent variable (response variable) to specified independent variables (explanatory variables). Regression analysis can be used as a descriptive method of data analysis (such as curve fitting) without relying on any assumptions about underlying processes generating the data.,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,Regression analysis is a descriptive statistics technique that examines the relation of a dependent variable (response variable) to specified independent variables (explanatory variables). Regression analysis can be used as a descriptive method of data analysis (such as curve fitting) without relying on any assumptions about underlying processes generating the data.,"BOOK: Richard A. Berk, Regression Analysis: A Constructive Critique, Sage Publications (2004) 978-0761929048",,,,,,regression analysis method,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200102,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,regression analysis method,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Tina Hernandez-Boussard,,
http://purl.obolibrary.org/obo/OBI_0000664,BrdU incorporation assay,,"A cell proliferation assay in which cells are cultured in the presence of BrdU which is incorporated into newly synthesized DNA of replicating cells (during the S phase of the cell cycle), substituting for thymidine during DNA replication, which can be quantified by BrdU specific antibodies.",false,,,http://purl.obolibrary.org/obo/OBI_0000891,,,,,,,,,,,,,,,,,,,"A cell proliferation assay in which cells are cultured in the presence of BrdU which is incorporated into newly synthesized DNA of replicating cells (during the S phase of the cell cycle), substituting for thymidine during DNA replication, which can be quantified by BrdU specific antibodies.",IEDB,,,,,,BrdU incorporation assay,,The measurement of T cell proliferation as a response to a viral peptide by culturing T cells stimulated with APCs and peptide in the presence of BrdU.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000664,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BrdU incorporation assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0400083,photodiode,,A photodiode is a semiconductor photodetector used to detect light and generate an electrical current. Typically used in forward scatter (FSC) detection. The photodiode collects the forward light scatter in a cytometer.,false,,,http://purl.obolibrary.org/obo/OBI_0400082,,,,,,,,,,,,,,,,,,,A photodiode is a semiconductor photodetector used to detect light and generate an electrical current. Typically used in forward scatter (FSC) detection. The photodiode collects the forward light scatter in a cytometer.,http://cyto.mednet.ucla.edu/Protocols/flow.htm,,,,,,photodiode,,Avalanche photodiode,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400083,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,photodiode,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0200000,data transformation,data processing|data analysis,A planned process that produces output data from input data.,false,,,http://purl.obolibrary.org/obo/OBI_0000011,,,,data processing|data analysis,,,,,,,,,,,,,,,A planned process that produces output data from input data.,Branch editors,,,,,,data transformation,,The application of a clustering protocol to microarray data or the application of a statistical testing method on a primary data set to determine a p-value.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000027,http://purl.obolibrary.org/obo/IAO_0000027,,,OBI:0200000,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,data transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Tina Hernandez-Boussard|James Malone|Helen Parkinson|Ryan Brinkman|Melanie Courtot|Richard Scheuermann|Elisabetta Manduchi|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001110,real-time PCR machine,,An PCR instrument that enables both detection and quantification of one or more specific sequences in a DNA sample.,false,,,http://purl.obolibrary.org/obo/OBI_0000989,,,,,,,,,,,,,,,,,,,An PCR instrument that enables both detection and quantification of one or more specific sequences in a DNA sample.,http://en.wikipedia.org/wiki/Real-time_polymerase_chain_reaction,,,,,,real-time PCR machine,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001110,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,real-time PCR machine,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001316,epitope specific interleukin-21 production by T cells,,A process of interleukin-21 production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0032625|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of interleukin-21 production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific interleukin-21 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001316,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific interleukin-21 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0302838,validated information,,"an information content entity which results from a validation process aimed at confirming a claim, a finding or a predicted information entity about a material entity or a process by experimental means.",false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,,,,,,,,,,,,,,,,"an information content entity which results from a validation process aimed at confirming a claim, a finding or a predicted information entity about a material entity or a process by experimental means.",OBI,,,,,,validated information,,"PMID: 20084519: ""..Three of four interactions were validated via functional magnetic resonance imaging (fMRI) in an independent sample of healthy controls;...""",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302838,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0302911,,,validated information,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001779,biological activity assay measuring epitope specific chemokine (C-X-C motif) ligand 13 production by T cells,CXCL13/BLC release|biological activity,A T cell epitope specific cytokine production assay that detects chemokine (C-X-C motif) ligand 13 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects chemokine (C-X-C motif) ligand 13 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific chemokine (C-X-C motif) ligand 13 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001779,,,,,,,,,,,,,,,,,,,,,,,,CXCL13/BLC release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific chemokine (C-X-C motif) ligand 13 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0200004,log-log curve fitting,,"A log-log curve fitting is a curve fitting where first a logarithmic transformation is applied both to the x and the y coordinates of the input data points (x_1, y_1), (x_2, y_2), ..., (x_n, y_n), and then coefficients a and b are determined to optimize the fit of log(y)=a+b*log(x) to these input data points.",false,,,http://purl.obolibrary.org/obo/OBI_0200072,,http://purl.obolibrary.org/obo/OBI_0200174,,,,,,,,,,,,,,,,,"A log-log curve fitting is a curve fitting where first a logarithmic transformation is applied both to the x and the y coordinates of the input data points (x_1, y_1), (x_2, y_2), ..., (x_n, y_n), and then coefficients a and b are determined to optimize the fit of log(y)=a+b*log(x) to these input data points.","ARTICLE: Plikaytis B.D. et al. (1991), J. Clin. Microbiol. 29(7): 1439-1446",,,,,,log-log curve fitting,,Typically used in an enzyme-linked immunosorbent assay (ELISA) to model the relationship between optical density (OD) and dilution.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200004,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,log-log curve fitting,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Ryan Brinkman|Melanie Courtot|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0001081,gel imaging system,,A device that is used to acquire images of laboratory gels.,false,,,http://purl.obolibrary.org/obo/OBI_0000398,,,,,,,,,,,,,,,,,,,A device that is used to acquire images of laboratory gels.,PERSON: Erik Segerdell,,,,,,gel imaging system,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453|http://purl.obolibrary.org/obo/OBI_0000397,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001081,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,gel imaging system,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001498,atmosphere,,A growth environment pertaining to the atmospheric conditions that is used to culture or grow an organism.,false,,,http://purl.obolibrary.org/obo/OBI_0000997,,,,,,,,,,,,,,,,,,,A growth environment pertaining to the atmospheric conditions that is used to culture or grow an organism.,MO_219 atmosphere,,,,,,atmosphere,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001498,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,atmosphere,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001471,T cell epitope specific immune intervention,,An epitope specific immune intervention in which the induced response targets a T cell epitope,false,,,http://purl.obolibrary.org/obo/OBI_0001192,,,,,,,,,,,,,,,,,,,An epitope specific immune intervention in which the induced response targets a T cell epitope,IEDB,,,,,,T cell epitope specific immune intervention,,Injecting a mouse with peptide SIINFEKL to induce a T cell response against the peptide,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001471,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,T cell epitope specific immune intervention,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/NCBITaxon_9989,Rodentia,rodents,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_314146,,,,rodents,,,,,,,,,,,,,,,,,,,,,,Rodentia,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:9989,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Rodentia,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PR_000025402,T cell receptor co-receptor CD8,,A protein complex that is a membrane-bound heterodimeric co-receptor for MHC class-I antigen/T-cell receptor interaction.,false,,,http://purl.obolibrary.org/obo/PR_000000001,,,,,,,,,,,,,,,,,,,A protein complex that is a membrane-bound heterodimeric co-receptor for MHC class-I antigen/T-cell receptor interaction.,,,,,,,T cell receptor co-receptor CD8,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PR:000025402,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pr.owl,,,,,,,,,,,,,,,,,,,T cell receptor co-receptor CD8,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/UBERON_0001134,skeletal muscle tissue,,Muscle tissue that consists primarily of skeletal muscle fibers.,false,,,http://purl.obolibrary.org/obo/CARO_0000043,,,,,,,,,,,,,,,,,,,Muscle tissue that consists primarily of skeletal muscle fibers.,,,,,,,skeletal muscle tissue,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UBERON:0001134,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uberon.owl,,,,,,,,,,,,,,,,,,,skeletal muscle tissue,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001560,obsolete cell lysate MHC binding constant determination assay,,An assay that measures the affinity of a ligand to a MHC in a cell lysate preparation and that quantifies the affinity with a binding constant.,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,An assay that measures the affinity of a ligand to a MHC in a cell lysate preparation and that quantifies the affinity with a binding constant.,IEDB,,,,,,obsolete cell lysate MHC binding constant determination assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,OBI:0001560,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete cell lysate MHC binding constant determination assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001242,detection of specific nucleic acids with complementary probes assay measuring epitope specific tumor necrosis factor production by T cells,TNFa release|RNA/DNA detection,A T cell epitope specific tumor necrosis factor production assay that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001416|http://purl.obolibrary.org/obo/OBI_0001788,,,,,,,,,,,,,,,,,,,A T cell epitope specific tumor necrosis factor production assay that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific tumor necrosis factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001242,,,,,,,,,,,,,,,,,,,,,,,,TNFa release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific tumor necrosis factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001263,biological activity assay measuring epitope specific helper T cell enhancement of a T cell mediated immune response,T cell help|biological activity,A T cell epitope specific helper activity assay that detects the ability of a T cell epitope to enhance a T cell response.,false,,,http://purl.obolibrary.org/obo/OBI_0001495,,,,,,,,,,,,,,,,,,,A T cell epitope specific helper activity assay that detects the ability of a T cell epitope to enhance a T cell response.,IEDB,,,,,,biological activity assay measuring epitope specific helper T cell enhancement of a T cell mediated immune response,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001263,,,,,,,,,,,,,,,,,,,,,,,,T cell help|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific helper T cell enhancement of a T cell mediated immune response,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000989,PCR instrument,,"A device that is used to amplify a single or few copies of a piece of DNA across several orders of magnitude, generating thousands to millions of copies of a particular DNA sequence.",false,,,http://purl.obolibrary.org/obo/OBI_0400116,,,,,,,,,,,,,,,,,,,"A device that is used to amplify a single or few copies of a piece of DNA across several orders of magnitude, generating thousands to millions of copies of a particular DNA sequence.",,,,,,03/21/2010: Added because it is unclear if the thermal cycler definition is intentionally broader than PCR instrument. Contacted Melanie and Trish about this. Definitions and use of alternative terms need to be made consistent.,PCR instrument,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000989,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PCR instrument,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"",,
http://purl.obolibrary.org/obo/OBI_0001933,value specification,,An information content entity that specifies a value within a classification scheme or on a quantitative scale.,false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,,,,,,,,,,,,,,,,An information content entity that specifies a value within a classification scheme or on a quantitative scale.,,,,,,"This term is currently a descendant of 'information content entity', which requires that it 'is about' something. A value specification of '20g' for a measurement data item of the mass of a particular mouse 'is about' the mass of that mouse. However there are cases where a value specification is not clearly about any particular. In the future we may change 'value specification' to remove the 'is about' requirement.",value specification,,"The value of 'positive' in a classification scheme of ""positive or negative""; the value of '20g' on the quantitative scale of mass.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001933,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,value specification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000974,obsolete_right handedness,,,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_right handedness,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000228,,,,,,,,,,,,,,,,,,OBI:0000974,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_right handedness,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000914,nasopharyngeal aspirate specimen,,"A speciemn which derives from nasopharyngeal mucosa after
aspiration.",false,,,http://purl.obolibrary.org/obo/OBI_0100051,,,,,,,,,,,,,,,,,,,"A speciemn which derives from nasopharyngeal mucosa after
aspiration.",WEB: http://www.wpro.who.int/NR/rdonlyres/EFD2B9A7-2265-4AD0-BC98-97937B4FA83C/0/manualonanimalaidiagnosisandsurveillance.pdf,,,,,,nasopharyngeal aspirate specimen,,type of sample used in the PCIRN influenza network,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000112,,,,,,,,,,,,OBI:0000914,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,nasopharyngeal aspirate specimen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0001610,cytometric bead array assay measuring epitope specific intracellular cytokine staining (ICS) IL-223 production by T cells,IL-23 release|cytometric bead array,An assay of epitope specific interleukin-23 production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001363,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-23 production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific intracellular cytokine staining (ICS) IL-223 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001610,,,,,,,,,,,,,,,,,,,,,,,,IL-23 release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific intracellular cytokine staining (ICS) IL-223 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000624,Bruker SampleJet system,,"Bruker BioSpin introduces the SampleJet, a robot for NMR tube automation. The SampleJet has been consciously designed to meet the growing customer demand for simplicity, versatility and higher throughput in NMR sample tube automation.\n  The SampleJet utilizes the modern-day industry standard for sample arrangements-the 96 well plate array. Therefore, the samples may be handled by standard lab automation devices before or after the NMR measurement.",false,,,http://purl.obolibrary.org/obo/OBI_0000464,,,,,,,,,,,,,,,,,NMR instrument,,"Bruker BioSpin introduces the SampleJet, a robot for NMR tube automation. The SampleJet has been consciously designed to meet the growing customer demand for simplicity, versatility and higher throughput in NMR sample tube automation.\n  The SampleJet utilizes the modern-day industry standard for sample arrangements-the 96 well plate array. Therefore, the samples may be handled by standard lab automation devices before or after the NMR measurement.",WEB:<http://www.bruker-biospin.com/automation.html>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400208,,,,,,Bruker SampleJet system,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000624,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker SampleJet system,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0002037,micrococcal nuclease digestion followed by tiling array assay,,"An array based nucleic acid structure mapping assay to identify nucleosome positions, genome wide, by detection of regions protected by nucleosomes from digestion by micrococal nuclease using tiling arrays.",false,,,http://purl.obolibrary.org/obo/OBI_0002036,,,,,,,,,,,,,,,,,,,"An array based nucleic acid structure mapping assay to identify nucleosome positions, genome wide, by detection of regions protected by nucleosomes from digestion by micrococal nuclease using tiling arrays.",,,,,,Details see tracker: https://sourceforge.net/p/obi/obi-terms/725/,micrococcal nuclease digestion followed by tiling array assay,,pmid:17873876,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002037,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,micrococcal nuclease digestion followed by tiling array assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Saccharomyces Genome Database (SGD),,,,,,,,"Janos Demeter, Chris Stoeckert",,
http://purl.obolibrary.org/obo/GO_0071706,tumor necrosis factor superfamily cytokine production,,"The appearance of any member of the TNF superfamily due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of any member of the TNF superfamily due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,tumor necrosis factor superfamily cytokine production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0071706,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,tumor necrosis factor superfamily cytokine production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001527,support service,,A service  in which the service provider assists the consumer in activities directly or indirectly associated with the production and analysis of experimental research data.,false,,,http://purl.obolibrary.org/obo/OBI_0001173,,,,,,,,,,,,,,,,,,,A service  in which the service provider assists the consumer in activities directly or indirectly associated with the production and analysis of experimental research data.,PERSON; Carlo Torniai,,,,,,support service,,An help desk for an instrument or a software. ,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001527,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,support service,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Carlo Torniai|PERSON: Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_1110116,splenocyte specimen,,"A cell specimen comprised of a mixed cell population obtained by processing whole spleen into individual cells, typically performed using a sieve or blender. This population includes T cells, B cells, macrophages, and other cell types.",false,,,http://purl.obolibrary.org/obo/OBI_0001468|http://purl.obolibrary.org/obo/OBI_0000953,,,,,,,,,,,,,,,,,,,"A cell specimen comprised of a mixed cell population obtained by processing whole spleen into individual cells, typically performed using a sieve or blender. This population includes T cells, B cells, macrophages, and other cell types.",IEDB,,,,,,splenocyte specimen,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110116,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,splenocyte specimen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/IAO_0000098,data format specification,,"A data format specification is the information content borne by the document published defining the specification.
Example: The ISO document specifying what encompasses an XML document; The instructions in a XSD file",false,,,http://purl.obolibrary.org/obo/IAO_0000033,,,,,,,,,,,,,,,,,,,"A data format specification is the information content borne by the document published defining the specification.
Example: The ISO document specifying what encompasses an XML document; The instructions in a XSD file",OBI branch derived|OBI_0000187,,,,,"2009-03-16: provenance: term imported from OBI_0000187, which had original definition ""A data format specification is a plan which organizes
information. Example: The ISO document specifying what encompasses an
XML document; The instructions in a XSD file""",data format specification,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000098,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,data format specification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch|PERSON: Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0001293,disease state design,,"A study design in which the pathological condition of a part, organ, or system of an organism is studied. The etiology may be from infection, genetic defect, or environmental stress.",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A study design in which the pathological condition of a part, organ, or system of an organism is studied. The etiology may be from infection, genetic defect, or environmental stress.",MO_902 disease_state_design,,,,,,disease state design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000268,,,,,,,,,,,,,,,,OBI:0001293,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,disease state design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001323,microRNA profiling by array design,,A study design in which a microRNA array is used to analyse the microRNA component of the transcriptome.,false,,,http://purl.obolibrary.org/obo/OBI_0001430,,,,,,,,,,,,,,,,,,,A study design in which a microRNA array is used to analyse the microRNA component of the transcriptome.,Group: ArrayExpress production team,,,,,,microRNA profiling by array design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001331,,,,,,,,,,,,,,,,OBI:0001323,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,microRNA profiling by array design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001771,ELISPOT assay measuring epitope specific vascular endothelial growth factor production by T cells,VEGF release|ELISPOT,An assay of epitope specific vascular endothelial growth factor production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001570,,,,,,,,,,,,,,,,,,,An assay of epitope specific vascular endothelial growth factor production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific vascular endothelial growth factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001771,,,,,,,,,,,,,,,,,,,,,,,,VEGF release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific vascular endothelial growth factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/PATO_0000918,volume,,A 3-D extent quality inhering in a bearer by virtue of the bearer's amount of 3-dimensional space it occupies.,false,,,http://purl.obolibrary.org/obo/PATO_0001237,,,,,,,,,,,,,,,,,,,A 3-D extent quality inhering in a bearer by virtue of the bearer's amount of 3-dimensional space it occupies.,,,,,,,volume,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0000918,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,volume,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/ENVO_00001998,soil,,"Soil is an environmental material which is primarily composed of minerals, varying proportions of sand, silt, and clay, organic material such as humus, gases, liquids, and a broad range of resident micro- and macroorganisms.",false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,"Soil is an environmental material which is primarily composed of minerals, varying proportions of sand, silt, and clay, organic material such as humus, gases, liquids, and a broad range of resident micro- and macroorganisms.",,,,,,,soil,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENVO:00001998,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/envo.owl,,,,,,,,,,,,,,,,,,,soil,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0400085,piezo electric crystal,,Apparatus in the fluidic subsystem of sorters that vibrates to break up the stream coming out of the flow chamber into droplets for sorting. The peizo electric crystal vibrates in a manner that breaks off droplets at regular intervals. Not all droplets contain a cell.,false,,,http://purl.obolibrary.org/obo/OBI_0001033,,,,,,,,,,,,,,,,,"think this is natural thing, not a device HP/JF",,Apparatus in the fluidic subsystem of sorters that vibrates to break up the stream coming out of the flow chamber into droplets for sorting. The peizo electric crystal vibrates in a manner that breaks off droplets at regular intervals. Not all droplets contain a cell.,http://www.flocyte.com/FRTP/Resources/flow_cytometry_glossary.htm,,,,,,piezo electric crystal,,"quartz piezoelectric crystal, topaz piezoelectric crystal, piezoelectric crystal in a sonar",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000377,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400085,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,piezo electric crystal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_1110154,ELISA measuring epitope specific interleukin-5 production by T cells,IL-5 release|ELISA,An assay of epitope specific interleukin-5 production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001230,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-5 production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific interleukin-5 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110154,,,,,,,,,,,,,,,,,,,,,,,,IL-5 release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific interleukin-5 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001174,passive immunization,adoptive transfer,"The injection of immune effector material (antibodies, T cells or B cells) into an organism so that the organisms immune system gains its  immune effector function to recognize specific antigens.",false,,,http://purl.obolibrary.org/obo/OBI_0600007,,,,adoptive transfer,,,,,,,,,,,,,,,"The injection of immune effector material (antibodies, T cells or B cells) into an organism so that the organisms immune system gains its  immune effector function to recognize specific antigens.",,,,,,,passive immunization,,"Giving VIG (concentrated antibodies from vaccinated donors) to a patient that is infected with smallpox. 
Transferring epitope specific T cells from one mouse into another.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001174,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,passive immunization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Bjoern Peters, Randi Vita, Jason Greenbaum",,
http://purl.obolibrary.org/obo/OBI_0302912,electroporation,electropermeabilization,"a process in which a significant increase in the electrical conductivity and permeability of the cell plasma membrane caused by an externally applied electrical field. It is usually used in molecular biology as a way of introducing some substance into a cell, such as loading it with a molecular probe, a drug that can change the cell's function, or a piece of coding DNA",false,,,http://purl.obolibrary.org/obo/OBI_0600033,,,,electropermeabilization,,,,,,,,,,,,,,,"a process in which a significant increase in the electrical conductivity and permeability of the cell plasma membrane caused by an externally applied electrical field. It is usually used in molecular biology as a way of introducing some substance into a cell, such as loading it with a molecular probe, a drug that can change the cell's function, or a piece of coding DNA",WEB:http://en.wikipedia.org/wiki/Electroporation,,,,,,electroporation,,PMID: 18551712. Microfluidic electroporation for selective release of intracellular molecules at the single-cell level. Electrophoresis. 2008 Jun 13.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0400142,,,,,,,,,,,http://purl.obolibrary.org/obo/CL_0000000,,,,OBI:0302912,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,electroporation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/IAO_0000582,time stamped measurement datum,,,false,,,http://purl.obolibrary.org/obo/IAO_0000109,,,,,,,,,,,,,,,,,,,,,,,,,,time stamped measurement datum,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000582,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,time stamped measurement datum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0002367,cytokine production involved in immune response,,"The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels.",,,,,,,cytokine production involved in immune response,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0002367,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,cytokine production involved in immune response,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/CARO_0000055,multi-tissue structure,,Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types.,false,,,http://purl.obolibrary.org/obo/CARO_0001008,,,,,,,,,,,,,,,,,,,Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types.,,,,,,,multi-tissue structure,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CARO:0000055,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/caro.owl,,,,,,,,,,,,,,,,,,,multi-tissue structure,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000541,Bruker AC series NMR instrument,,"A series of older Bruker NMR magnets, now out of production.",false,,,http://purl.obolibrary.org/obo/OBI_0000596,,,,,,,,,,,,,,,,,NMR instrument,,"A series of older Bruker NMR magnets, now out of production.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400241,,,,,,Bruker AC series NMR instrument,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000541,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker AC series NMR instrument,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0200014,split-scale transformation,,"A split-scale transformation is a data transformation which is an application of a function f described as follows to a (one dimensional) real number input. f(x)=a*x+b if x=for x>t; where log denotes a logarithmic transformation and a, b, c, d, r, t are real constants, with a, c, d, r, t positive, chosen so that f is continuous with a continuous derivative at the transition point t.",false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,"A split-scale transformation is a data transformation which is an application of a function f described as follows to a (one dimensional) real number input. f(x)=a*x+b if x=for x>t; where log denotes a logarithmic transformation and a, b, c, d, r, t are real constants, with a, c, d, r, t positive, chosen so that f is continuous with a continuous derivative at the transition point t.",WEB: http://flowcyt.sourceforge.net/gating/latest.pdf,,,,,,split-scale transformation,,This type of transformation is typically used in flow cytometry,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200014,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,split-scale transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Ryan Brinkman|Joseph Spliden|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_1110300,direct submission to IEDB,,"A report about experiments in an investigation that characterize immune epitopes, and was submitted directly by the authors to the Immune Epitope Database (IEDB)",false,,,http://purl.obolibrary.org/obo/IAO_0000088,,,,,,,,,,,,,,,,,,,"A report about experiments in an investigation that characterize immune epitopes, and was submitted directly by the authors to the Immune Epitope Database (IEDB)",IEDB,,,,,,direct submission to IEDB,,"The report on ""Identification of a dominant CD4 T cell epitope in the membrane lipoprotein Tul4 from Francisella tularensis LVS. "" submitted by Valentino et al to the IEDB. 

The content of that report on the IEDB website is here: http://iedb.org/refId/1013357",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110300,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,direct submission to IEDB,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001976,hydrogen/deuterium exchange assay,,"An assay that uses a chemical reaction whereby a covalently bonded hydrogen atom is replaced by a deuterium atom, or vice versa in order to gather information about the solvent accessibility of parts of a molecule and thus its tertiary structure.",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,"An assay that uses a chemical reaction whereby a covalently bonded hydrogen atom is replaced by a deuterium atom, or vice versa in order to gather information about the solvent accessibility of parts of a molecule and thus its tertiary structure.",IEDB,,,,,,hydrogen/deuterium exchange assay,,"Performing deuterium exchange on a protein by itself and in the presence of a binding partner, degrading the protein into peptide segments and identifying where deuterium exchange occurred by detecting the peptides in Mass Spectrometry. Peptides that have a modified deuteration pattern when the protein was bound to a partner are expected to be part of the binding interface.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001976,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,hydrogen/deuterium exchange assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001228,biological activity assay measuring epitope specific helper T cell enhancement of a B cell mediated immune response,antibody help|biological activity,A T cell epitope specific helper activity assay that detects the ability of a T cell epitope to enhance an antibody response.,false,,,http://purl.obolibrary.org/obo/OBI_0001495,,,,,,,,,,,,,,,,,,,A T cell epitope specific helper activity assay that detects the ability of a T cell epitope to enhance an antibody response.,IEDB,,,,,,biological activity assay measuring epitope specific helper T cell enhancement of a B cell mediated immune response,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001228,,,,,,,,,,,,,,,,,,,,,,,,antibody help|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific helper T cell enhancement of a B cell mediated immune response,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000561,Bruker NMR probe,,An NMR probe that is manufactured by Bruker.,false,,,http://purl.obolibrary.org/obo/OBI_0000516,,,,,,,,,,,,,,,,,"NMR device, TODO: May need no definition.",,An NMR probe that is manufactured by Bruker.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400231,,,,,,Bruker NMR probe,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000561,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bruker NMR probe,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001687,contact representative role,,"A role inhering in a person who represents an institution, organization, or service provider and realized when communication is directed at them about the entity they represent.",false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,,,"A role inhering in a person who represents an institution, organization, or service provider and realized when communication is directed at them about the entity they represent.",,,,,,"Discussed on May 7, 2012 dev call
propose:contact role, type of organization role, and create shortcut relation between 'organization role' and 'organization' ?
Whether it works for communicating author in manuscript or not?
Tracker:
https://sourceforge.net/tracker/?func=detail&aid=3512891&group_id=177891&atid=886178",contact representative role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001687,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/NCBITaxon_9606,,,,,,,,,,,,,,,,,contact representative role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,Person: Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0000831,DNA residue methylation,,a quality of a DNA residue that has a methyl group attached to it,false,,,http://purl.obolibrary.org/obo/PATO_0001237,,,,,,,,,,,,,,,,,,,a quality of a DNA residue that has a methyl group attached to it,,,,,,,DNA residue methylation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000831,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNA residue methylation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000545,column compartment,,"For chromatography analyses, the ability to maintain a stable column environment regardless of ambient temperature fluctuations is critical for maintaining retention time precision. In order to ensure such stable conditions at different chromatography steps a column compartment can be installed that ensures e.g. stable temperature of the column in a given step.",false,,,http://purl.obolibrary.org/obo/OBI_0000048,,,,,,,,,,,,,,,,,,,"For chromatography analyses, the ability to maintain a stable column environment regardless of ambient temperature fluctuations is critical for maintaining retention time precision. In order to ensure such stable conditions at different chromatography steps a column compartment can be installed that ensures e.g. stable temperature of the column in a given step.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01068,,,,,,column compartment,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000545,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,column compartment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000499,NMR console,,A component of an NMR instrument that controls the activities of the other components.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,"NMR instrument, TODO: same as or part of acquisition computer?",,A component of an NMR instrument that controls the activities of the other components.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400015,,,,,,NMR console,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000499,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NMR console,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000439,agarose gel,,a material entity resulting from the polymerization of agarose after heating agarose suspended in some buffer solution,false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,,,,,,,,,,,,,,,,a material entity resulting from the polymerization of agarose after heating agarose suspended in some buffer solution,GROUP: OBI Biomaterial Branch,,,,,,agarose gel,,Performance comparison of capillary and agarose gel electrophoresis for the identification and characterization of monoclonal immunoglobulins. Am J Clin Pathol. 2008 Mar;129(3):451-8. PMID: 18285269,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000439,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0302890,,,agarose gel,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000278,disease stage,,a part of an occurrence of a disease process which is associated with position in the normal progression of the disease,false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,a part of an occurrence of a disease process which is associated with position in the normal progression of the disease,,,,,,,disease stage,,"Stage II breast cancer, The timepoint of recovery from a disease",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OGMS_0000063,OBI:0000278,http://purl.obolibrary.org/obo/OGMS_0000063,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,disease stage,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Bjoern peters,,
http://purl.obolibrary.org/obo/OBI_0001021,RNASE T2 structure mapping assay,single nucleotide resolution mapping assay using RNAse T2,a single-nucleotide-resolution ribonucleic acid structure mapping assay which uses RNAse T2 as reagent and enzymatic probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,false,,,http://purl.obolibrary.org/obo/OBI_0001014,,http://purl.obolibrary.org/obo/OBI_0000441,,single nucleotide resolution mapping assay using RNAse T2,,,,,,,,,,,,,,,a single-nucleotide-resolution ribonucleic acid structure mapping assay which uses RNAse T2 as reagent and enzymatic probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure,RNA ontology,,,,,,RNASE T2 structure mapping assay,,PMID:6207483,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_33697,,,,OBI:0001021,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,RNASE T2 structure mapping assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000819,anticoagulant tube storage of blood specimen,,Storage of a blood specimen in a tube with anticoagulant,false,,,http://purl.obolibrary.org/obo/OBI_0302893,,,,,,,,,,,,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,,Storage of a blood specimen in a tube with anticoagulant,,,,,,,anticoagulant tube storage of blood specimen,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000819,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,anticoagulant tube storage of blood specimen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0000224,sub-investigator role,sub-investigator,a worker role authorized to make study-related decisions and carry out tasks related to the study; this role occurs during the study timeline,false,,,http://purl.obolibrary.org/obo/OBI_0000116,,,,sub-investigator,,,,,,,,,,,,,"CDISC definition:  Sub-investigator. Any member of the clinical trial team designated and supervised by the investigator at a trial site to perform critical trial-related procedures and/or to make important trial-related decisions (e.g., associates, residents, research fellows) [ICH] See associates, residents, research fellows",,a worker role authorized to make study-related decisions and carry out tasks related to the study; this role occurs during the study timeline,,,,,,,sub-investigator role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000224,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sub-investigator role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_1110021,infection process,,the detrimental process in which an infectious agent colonizes or replicates in a host environment,false,,,http://purl.obolibrary.org/obo/OBI_1110122,,,,,,,,,,,,,,,,,,,the detrimental process in which an infectious agent colonizes or replicates in a host environment,IEDB,,,,,,infection process,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IDO_0000586,,,,,,,,,,,,,,,OBI:1110021,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,infection process,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_1110093,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001923,protein sequencing by tandem mass spectrometry assay,,A sequencing assay in which amino acid sequences of proteins is determined using multiple rounds of mass spectrometry and molecule fragmentation.,false,,,http://purl.obolibrary.org/obo/OBI_0600047,,,,,,,,,,,,,,,,,,,A sequencing assay in which amino acid sequences of proteins is determined using multiple rounds of mass spectrometry and molecule fragmentation.,Hunt et al. Protein sequencing by tandem mass spectrometry. Proc Natl Acad Sci U S A. 1986;83(17): 6233–6237. [PMID:3462691],,,,,,protein sequencing by tandem mass spectrometry assay,,Taylor et al.Implementation and uses of automated de novo peptide sequencing by tandem mass spectrometry. Anal Chem. 2001 Jun;73(11):2594-604. [PMID:11403305],,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0600056,http://purl.obolibrary.org/obo/OBI_0001088,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000973,,,OBI:0001923,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,protein sequencing by tandem mass spectrometry assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000751,study design dependent variable,dependent variable,dependent variable specification is part of a study design. The dependent variable is the event studied and expected to change when the independent variable varies.,false,,,http://purl.obolibrary.org/obo/IAO_0000033,,,,dependent variable,,,,,,,,,,,,,2009-03-16: work has been done on this term during during the OBI workshop winter 2009 and the current definition was considered acceptable for use in OBI. If there is a need to modify thisdefinition please notify OBI.,,dependent variable specification is part of a study design. The dependent variable is the event studied and expected to change when the independent variable varies.,WEB: http://en.wikipedia.org/wiki/Dependent_and_independent_variables,,,,,"In the Philly 2013 workshop the label was chosen to distinguish it from ""dependent variable"" as used in statistical modelling. See: http://en.wikipedia.org/wiki/Statistical_modeling|2/2/2009 In the design of experiments, independent variables are those whose values are controlled or selected by the person experimenting (experimenter) to determine its relationship to an observed phenomenon (the dependent variable). In such an experiment, an attempt is made to find evidence that the values of the independent variable determine the values of the dependent variable (that which is being measured). The independent variable can be changed as required, and its values do not represent a problem requiring explanation in an analysis, but are taken simply as given. The dependent variable on the other hand, usually cannot be directly controlled.",study design dependent variable,,"In a study in which gene expression is measured in patients between 8 month to 4 years old that have mild or severe malaria and in which the hypothesis is that gene expression in that age group is a function of disease status, the gene expression is the dependent variable. ",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0500000,OBI:0000751,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,study design dependent variable,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Alan Ruttenberg|PERSON: Bjoern Peters|PERSON: Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0001328,organism development design,,A study design that assays events associated with development. Development applies to organism(s) acquiring a mature state.,false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,A study design that assays events associated with development. Development applies to organism(s) acquiring a mature state.,MO_892 development_or_differentiation_design,,,,,,organism development design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001328,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,organism development design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/GO_0044030,regulation of DNA methylation,,"Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.",false,,,http://purl.obolibrary.org/obo/GO_0040030,,,,,,,,,,,,,,,,,,,"Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.",,,,,,,regulation of DNA methylation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0044030,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,regulation of DNA methylation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000577,obsolete_molecular concentration,,A concentration is a relational quality that inheres in a material entity towards molecular scattered aggregate that is part of it by virtue of some ratio of masses of the two or the counts of the grains of the two or volume occupied by the larger material entity.,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,A concentration is a relational quality that inheres in a material entity towards molecular scattered aggregate that is part of it by virtue of some ratio of masses of the two or the counts of the grains of the two or volume occupied by the larger material entity.,"Discussion in Karslruhe, Oct 2008, with, among others, Alan Rector, Stefan Schulz, Marijke Keet, Melanie Courtot, and Alan Ruttenberg.",,,,,"logical definition in OBI:
  'quality of related physical entities'
  ('inheres in' some material_entity) and (towards some 'scattered molecular aggregate')|This term represent a quality of molecular concentration. If there is need for some other sort of concentration - e.g. ratio of counts of cells, another term is needed. 

OBI uses a standard unit for representing concentration qualities but this still needs to be decided on. A relation needs to be defined that relates the quality instance to the representation of its quantitative value in the chosen units. See http://en.wikipedia.org/wiki/Concentration

Measurements of concentration may be in any appropriate unit. Note that precise concentrations are virtually never known.

Finally, note that there is no such thing as a concentration of 0. A concentration is a *relational* quality and so can't exist unless both entities it inheres in exist. However one map make concentration measurements that turn out not to be about concentrations qualities, if it happens that the scattered molecular aggregate doesn't actually exist.|JZ: Can we replace the term by PATO:
http://purl.obolibrary.org/obo/PATO_0000033
If not, we will wait the term available in PATO.

Although specified that obsolete reason is 'term imported', the term has not imported yet. Will keep tracking this term until import the replaced term.

Term depracted since the object property 'towards' used in the axioms is not avaliable in BFO2. ",obsolete_molecular concentration,,the phosphate concentration should be 0.1M,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000228,,,,,,,,,,,,,,,,,,OBI:0000577,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_molecular concentration,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0000605,chart recorder,,"The chart recorder is a device that transduces signal-intensities into a graphical peak output: As the separated components of the gas sample emerge into the detector, the change in voltage in the detecting bridge circuit causes a representative peak to be drawn on a chart recorder. The position of the peak along the time axis of the chart measures the component's retention time, which identifies the component. This is directly related to carrier gas flow rate, temperature and column packing and dimensions. The area under each peak is proportional to the concentration of the component of the sample. The area of the peaks inscribed on the chart recorder can be determined by multiplying the height of the peak in mm, by the width of the peak in mm at 1/2 the peak height. The calibration curves for use with the chart recorder are therefore peak area plotted against concentration.",false,,,http://purl.obolibrary.org/obo/OBI_0000048,,,,,,,,,,,,,,,,,chromatography device,,"The chart recorder is a device that transduces signal-intensities into a graphical peak output: As the separated components of the gas sample emerge into the detector, the change in voltage in the detecting bridge circuit causes a representative peak to be drawn on a chart recorder. The position of the peak along the time axis of the chart measures the component's retention time, which identifies the component. This is directly related to carrier gas flow rate, temperature and column packing and dimensions. The area under each peak is proportional to the concentration of the component of the sample. The area of the peaks inscribed on the chart recorder can be determined by multiplying the height of the peak in mm, by the width of the peak in mm at 1/2 the peak height. The calibration curves for use with the chart recorder are therefore peak area plotted against concentration.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01069,,,,,,chart recorder,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000605,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,chart recorder,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/GO_0008228,opsonization,,"The process in which a microorganism (or other particulate material) is rendered more susceptible to phagocytosis by coating with an opsonin, a blood serum protein such as a complement component or antibody.",false,,,http://purl.obolibrary.org/obo/GO_0006909,,,,,,,,,,,,,,,,,,,"The process in which a microorganism (or other particulate material) is rendered more susceptible to phagocytosis by coating with an opsonin, a blood serum protein such as a complement component or antibody.",,,,,,,opsonization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0008228,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,opsonization,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001558,cell bound MHC direct binding assay measuring half life of a MHC:ligand complex using radioactivity detection,half life|cellular MHC/direct/radioactivity|min,A cell bound MHC ligand half life of binding determination assay that uses radioactivity detection to measure direct ligand binding.,false,,,http://purl.obolibrary.org/obo/OBI_0001990|http://purl.obolibrary.org/obo/OBI_0001491,,,,,,,,,,,,,,,,,,,A cell bound MHC ligand half life of binding determination assay that uses radioactivity detection to measure direct ligand binding.,IEDB,,,,,,cell bound MHC direct binding assay measuring half life of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001558,,,,,,,,,,,,,,,,,,,,,,,,half life|cellular MHC/direct/radioactivity|min,,,,,,,,,,,,,,,,,,,,,,cell bound MHC direct binding assay measuring half life of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/CHEBI_4705,double-stranded DNA,,,false,,,http://purl.obolibrary.org/obo/CHEBI_16991,,,,,,,,,,,,,,,,,,,,,,,,,,double-stranded DNA,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:4705,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,double-stranded DNA,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000273,role of regulator of consumables and medical devices,drug regulatoy authority,"a regulator involved with making and enforcing legislation and governmental orders relevant to the development, testing, manufacture and use of food, drugs and medical devices",false,,,http://purl.obolibrary.org/obo/OBI_0000014,,,,drug regulatoy authority,,,,,,,,,,,,,,,"a regulator involved with making and enforcing legislation and governmental orders relevant to the development, testing, manufacture and use of food, drugs and medical devices","OBI, CDISC",,,,,,role of regulator of consumables and medical devices,,"FDA, EMEA; http://www.fda.gov/; The International Conference of Drug Regulatory Authorities (ICDRAs) provide drug regulatory authorities of WHO Member States with a forum to meet and discuss ways to strengthen collaboration.http://www.who.int/medicines/areas/quality_safety/regulation_legislation/icdra/en/index.html",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000273,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,role of regulator of consumables and medical devices,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0000633,column heater,,"The glass liner can be fitted with a separate heater and the volatilization temperature can, thus, be controlled. This flash heater system is available in most chromatographs. By using a syringe with a long needle, the tip can be made to penetrate past the liner and discharge its contents directly into the column packing. This procedure is called 'on-column injection' and, as it reduces peak dispersion on injection and thus, provides higher column efficiencies, is often the preferred procedure.",false,,,http://purl.obolibrary.org/obo/OBI_0000485,,,,,,,,,,,,,,,,,,,"The glass liner can be fitted with a separate heater and the volatilization temperature can, thus, be controlled. This flash heater system is available in most chromatographs. By using a syringe with a long needle, the tip can be made to penetrate past the liner and discharge its contents directly into the column packing. This procedure is called 'on-column injection' and, as it reduces peak dispersion on injection and thus, provides higher column efficiencies, is often the preferred procedure.",WEB:<http://www.chromatography-online.org/GC/Injection-Devices/Open-Tubular-Column/rs15.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01040,,,,,,column heater,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000633,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,column heater,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0302894,cell lysis,,cell lysis is a process by which cell membrane integrity of live cells  is compromised and leads to cell death. Cell lysis may be achieved by means of viral action or osmotic shock.,false,,,http://purl.obolibrary.org/obo/OBI_0600006,,,,,,,,,,,,,,,,,,,cell lysis is a process by which cell membrane integrity of live cells  is compromised and leads to cell death. Cell lysis may be achieved by means of viral action or osmotic shock.,adapted from wikipedia [http://en.wikipedia.org/wiki/Lysis],,,,,"BP, JG, RV: There is also a need for the unplanned cell lysis, which is probably not in the scope of OBI, but should be linked to from this process.",cell lysis,,PMID: 18484276.Cell lysis with dimethyl sulphoxide produces stable homogeneous solutions in the dichlorofluorescein oxidative stress assay. Free Radic Res. 2008 May;42(5):435-41.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302894,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cell lysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0200021,linlog transformation,,"A linlog transformation is a data transformation, described in PMID 16646782, whose input is a matrix [y_ik] and whose output is a matrix obtained by applying formula (9) of this paper, where values below an appropriately determined threshold (dependent on the row i) are transformed via a polynomial of degree 1, and values above this threshold are transformed via a logarithm.",false,,,http://purl.obolibrary.org/obo/OBI_0200169,,http://purl.obolibrary.org/obo/OBI_0200167,,,,,,,,,,,,,,,,,"A linlog transformation is a data transformation, described in PMID 16646782, whose input is a matrix [y_ik] and whose output is a matrix obtained by applying formula (9) of this paper, where values below an appropriately determined threshold (dependent on the row i) are transformed via a polynomial of degree 1, and values above this threshold are transformed via a logarithm.",PMID: 16646782,,,,,,linlog transformation,,"This can be used for microarray normalization, e.g. to normalize the data from a two-channel expression microarray assay, as described in PMID 16646782.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200021,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,linlog transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001726,quenching assay measuring binding of a B cell epitope:antibody complex,qualitative binding|quenching,A B cell epitope qualitative binding to antibody assay that uses an antibody binding detection by fluorescence quenching.,false,,,http://purl.obolibrary.org/obo/OBI_0001703|http://purl.obolibrary.org/obo/OBI_0001499,,,,,,,,,,,,,,,,,,,A B cell epitope qualitative binding to antibody assay that uses an antibody binding detection by fluorescence quenching.,IEDB,,,,,,quenching assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001726,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|quenching,,,,,,,,,,,,,,,,,,,,,,quenching assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/BFO_0000145,relational quality,,"b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001])",false,,,http://purl.obolibrary.org/obo/BFO_0000019,,,,,,,RelationalQuality,r-quality,,,,,,,,,,,"b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001])",,,,,,,relational quality,,"a marriage bond, an instance of love, an obligation between one person and another.|John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married.",,,,,,,,(iff (RelationalQuality a) (exists (b c t) (and (IndependentContinuant b) (IndependentContinuant c) (qualityOfAt a b t) (qualityOfAt a c t)))) // axiom label in BFO2 CLIF: [057-001] ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000145,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,relational quality,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001936,molecular-labeled material,,a material entity that is the specified output of an addition of molecular label process that aims to label some molecular target to allow for its detection in a detection of molecular label assay,false,,,http://purl.obolibrary.org/obo/OBI_0000047|http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,a material entity that is the specified output of an addition of molecular label process that aims to label some molecular target to allow for its detection in a detection of molecular label assay,"OBI developer call, 3-12-12",,,,,,molecular-labeled material,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001936,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,molecular-labeled material,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Matthew Brush,,
http://purl.obolibrary.org/obo/OBI_0000469,solvent mixer,,"A liquid chromatography device that mixes different solvents, e.g. under high pressure and in differrent volumes ranging from 5 ml to 5 L capacity. Powerful magnetic mixers provide vigorous agitation required for high pressure reaction chemistry.",false,,,http://purl.obolibrary.org/obo/OBI_0000485,,,,,,,,,,,,,,,,,check on definition !,,"A liquid chromatography device that mixes different solvents, e.g. under high pressure and in differrent volumes ranging from 5 ml to 5 L capacity. Powerful magnetic mixers provide vigorous agitation required for high pressure reaction chemistry.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01072,,,,,,solvent mixer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000469,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,solvent mixer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000607,high resolution magic angle spin probe,"high resolution MAS, hr-MAS","Samples that are neither solid nor liquid, being of biological, chemical, or pharmaceutical interest, reveal highly resolved spectra when magic angle spinning is applied. The correct solution is a gradient, such that the field varies along the spinner axis. This so-called Magic Angle Gradient is employed in Brukers high resolution Magic Angle Spinning (hr-MAS) probes, and is implemented in such a way that it is compatible with the stator and does not interfere with the sample eject or insert. Bruker BioSpin has developed a series of dedicated probes for standard bore magnets to accommodate the rapidly expanding field of hr-MAS. These probes are available in double (e.g. 1H and 13C) and triple resonance (e.g. 1H, 13C, 15N) modes and come equipped with a deuterium lock channel. The probes have automatic sample ejection and insertion capability, with the availability of an optional sample changer, enabling fully automated sample runs. Probes can be equipped with an optional B0 gradient, directed along the magic angle, so that gradient spectroscopy can be done used.",false,,,http://purl.obolibrary.org/obo/OBI_0000480,,,,"high resolution MAS, hr-MAS",,,,,,,,,,,,,NMR probe,,"Samples that are neither solid nor liquid, being of biological, chemical, or pharmaceutical interest, reveal highly resolved spectra when magic angle spinning is applied. The correct solution is a gradient, such that the field varies along the spinner axis. This so-called Magic Angle Gradient is employed in Brukers high resolution Magic Angle Spinning (hr-MAS) probes, and is implemented in such a way that it is compatible with the stator and does not interfere with the sample eject or insert. Bruker BioSpin has developed a series of dedicated probes for standard bore magnets to accommodate the rapidly expanding field of hr-MAS. These probes are available in double (e.g. 1H and 13C) and triple resonance (e.g. 1H, 13C, 15N) modes and come equipped with a deuterium lock channel. The probes have automatic sample ejection and insertion capability, with the availability of an optional sample changer, enabling fully automated sample runs. Probes can be equipped with an optional B0 gradient, directed along the magic angle, so that gradient spectroscopy can be done used.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400192,,,,,,high resolution magic angle spin probe,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000607,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,high resolution magic angle spin probe,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/GO_0043565,sequence-specific DNA binding,,"Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.",false,,,http://purl.obolibrary.org/obo/OBI_0001588,,,,,,,,,,,,,,,,,,,"Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.",,,,,,,sequence-specific DNA binding,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0043565,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,sequence-specific DNA binding,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001315,ELISA measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells,CCL1/TCA-3 release|ELISA,An assay of epitope specific chemokine (C-C motif) ligand 1 production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001276,,,,,,,,,,,,,,,,,,,An assay of epitope specific chemokine (C-C motif) ligand 1 production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001315,,,,,,,,,,,,,,,,,,,,,,,,CCL1/TCA-3 release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/GO_0032635,interleukin-6 production,,"The appearance of interleukin-6 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-6 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-6 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032635,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-6 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032638,interleukin-9 production,,"The appearance of interleukin-9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-9 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032638,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-9 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032637,interleukin-8 production,,"The appearance of interleukin-8 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-8 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-8 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032637,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-8 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032634,interleukin-5 production,,"The appearance of interleukin-5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-5 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032634,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-5 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032632,interleukin-3 production,,"The appearance of interleukin-3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-3 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032632,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-3 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032630,interleukin-26 production,,"The appearance of interleukin-26 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-26 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-26 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032630,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-26 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032633,interleukin-4 production,,"The appearance of interleukin-4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-4 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032633,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-4 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032636,interleukin-7 production,,"The appearance of interleukin-7 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-7 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-7 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032636,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-7 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032631,interleukin-27 production,,"The appearance of interleukin-27 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of interleukin-27 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,interleukin-27 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032631,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,interleukin-27 production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0032639,TRAIL production,,"The appearance of TRAIL due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The appearance of TRAIL due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,TRAIL production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0032639,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,TRAIL production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000429,intraperitoneal administration,,The administration of a substance into the peritoneum of an organism,false,,,http://purl.obolibrary.org/obo/OBI_0600007,,http://purl.obolibrary.org/obo/OBI_0000434,,,,,,,,,,,,,,,,,The administration of a substance into the peritoneum of an organism,,,,,,,intraperitoneal administration,,Rats were injected intraperitoneally with either rrIL-6 (250 ng/0.5 ml) or equal-volume sterile saline twice within an interval of 24 h,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000429,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,intraperitoneal administration,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001823,epitope specific chemokine (C-C motif) ligand 21 production by T cells,,A process of chemokine (C-C motif) ligand 21 production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0097389|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,Date: 2012-11-16; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mappings: MMExpressionsTcell.txt,,A process of chemokine (C-C motif) ligand 21 production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific chemokine (C-C motif) ligand 21 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001823,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific chemokine (C-C motif) ligand 21 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/CL_0000767,basophil,,"Any of the immature or mature forms of a granular leukocyte that in its mature form has an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse, bluish-black granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. A basophil is CD123-positive, CD193-positive, CD203c-positive, and FceRIa-positive.",false,,,http://purl.obolibrary.org/obo/CL_0000000,,,,,,,,,,,,,,,,,,,"Any of the immature or mature forms of a granular leukocyte that in its mature form has an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse, bluish-black granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. A basophil is CD123-positive, CD193-positive, CD203c-positive, and FceRIa-positive.",,,,,,,basophil,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CL:0000767,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/cl.owl,,,,,,,,,,,,,,,,,,,basophil,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001774,biological activity assay measuring epitope specific chemokine (C-C motif) ligand 21 production by T cells,CCL21/SLC release|biological activity,A T cell epitope specific cytokine production assay that detects chemokine (C-C motif) ligand 21 production by T cells.,false,,,http://purl.obolibrary.org/obo/OBI_1110129,,,,,,,,,,,,,,,,,,,A T cell epitope specific cytokine production assay that detects chemokine (C-C motif) ligand 21 production by T cells.,IEDB,,,,,,biological activity assay measuring epitope specific chemokine (C-C motif) ligand 21 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001774,,,,,,,,,,,,,,,,,,,,,,,,CCL21/SLC release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific chemokine (C-C motif) ligand 21 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001247,genotyping by high throughput sequencing assay,,An assay in which high througput sequencer is used to detect polymorphisms in DNA samples,false,,,http://purl.obolibrary.org/obo/OBI_0000435,,,,,,,,,,,,,,,,,,,An assay in which high througput sequencer is used to detect polymorphisms in DNA samples,EFO_0002771: genotyping by high throughput sequencing,,,,,,genotyping by high throughput sequencing assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0400103,,,,,,,,,,,,,,,OBI:0001247,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,genotyping by high throughput sequencing assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: James Malone,,
http://purl.obolibrary.org/obo/OBI_0002046,surface plasmon resonance sensor chip,biosensor chip|SPR sensor chip|sensor chip,"a device that is used as a binding surface for ligand during a surface plasmon resonance assay, consisting of a glass plate to which a metal film is attached",false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,biosensor chip|SPR sensor chip|sensor chip,,,,,,,,,,,,,,,"a device that is used as a binding surface for ligand during a surface plasmon resonance assay, consisting of a glass plate to which a metal film is attached",OBI,,,,,,surface plasmon resonance sensor chip,,ProteOn GLC Sensor Chip #176-5011,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,http://purl.obolibrary.org/obo/OBI_0000399,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001136,OBI:0002046,http://purl.obolibrary.org/obo/OBI_0001136,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,surface plasmon resonance sensor chip,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Anna Maria Masci,,
http://purl.obolibrary.org/obo/OBI_0002076,collection of specimens,,A material entity that has two or more specimens as its parts.,false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,A material entity that has two or more specimens as its parts.,"OBIB, OBI",,,,,Details see tracker: https://sourceforge.net/p/obi/obi-terms/778/,collection of specimens,,Blood cells collected from multiple donors over the course of a study.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002076,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,collection of specimens,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Biobank,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001522,sequence assembly algorithm,Assembly Algorithm,"An algorithm used to assemble individual sequence reads into larger contiguous sequences (contigs).  Assembly details include but are not limited to assembler type (overlap-layout-consensus, deBruijn), assembler version, and any relevant quality control information such as per cent known genes/ESTs captured.",false,,,http://purl.obolibrary.org/obo/IAO_0000064,,,,,,,,,,,,,,,,,,,"An algorithm used to assemble individual sequence reads into larger contiguous sequences (contigs).  Assembly details include but are not limited to assembler type (overlap-layout-consensus, deBruijn), assembler version, and any relevant quality control information such as per cent known genes/ESTs captured.",NIAID GSCID-BRC metadata working group,,,,,,sequence assembly algorithm,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001522,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sequence assembly algorithm,,,,,,Assembly Algorithm,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0002004,Methylation 450K BeadChip,Illumina Infinium Human Methylation 450K BeadChip,"A methylation BeadChip which is manufactured by the Illumina corporation. Built upon BeadChip tehcnology, the array interrogates ~ 485,000 methylation sites per sample at single-nucleotide resolution.",false,,,http://purl.obolibrary.org/obo/OBI_0001870,,,,Illumina Infinium Human Methylation 450K BeadChip,,,,,,,,,,,,,,,"A methylation BeadChip which is manufactured by the Illumina corporation. Built upon BeadChip tehcnology, the array interrogates ~ 485,000 methylation sites per sample at single-nucleotide resolution.",http://www.illumina.com/products/methylation_450_beadchip_kits.ilmn,,,,,,Methylation 450K BeadChip,,"Naumov, Vladimir A., et al. ""Genome-scale analysis of DNA methylation in colorectal cancer using Infinium HumanMethylation450 BeadChips."" Epigenetics 8.9 (2013): 0-1. PMID: 23867710",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002004,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Methylation 450K BeadChip,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"PERSON: Venkat Malladi, Chris Stoeckert, Jie Zheng, Alan Ruttenberg",,
http://purl.obolibrary.org/obo/OBI_0002029,serial analysis of gene expression,SAGE,A transcription profiling assay which aims to quantify RNA through creating short signature tags of the messages and ligating them into a larger molecule that is than sequenced. ,false,,,http://purl.obolibrary.org/obo/OBI_0000424,,,,SAGE,,,,,,,,,,,,,,,A transcription profiling assay which aims to quantify RNA through creating short signature tags of the messages and ligating them into a larger molecule that is than sequenced. ,PMID:7570003,,,,,Details see tracker: https://sourceforge.net/p/obi/obi-terms/720/,serial analysis of gene expression,,PMID:15905473,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0002028|http://purl.obolibrary.org/obo/OBI_0600047,http://purl.obolibrary.org/obo/OBI_0400103,,,,,,,,,,,,,,,OBI:0002029,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,serial analysis of gene expression,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Saccharomyces Genome Database (SGD),,,,,,,,"Person:Janos Demeter, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0200163,false discovery rate correction method,FDR correction method,"The false discovery rate is a  data transformation used in multiple hypothesis testing to correct for multiple comparisons. It controls the expected proportion of incorrectly rejected null hypotheses (type I errors) in a list of rejected hypotheses. It is a less conservative comparison procedure with greater power than familywise error rate (FWER) control, at a cost of increasing the likelihood of obtaining type I errors. .",false,,,http://purl.obolibrary.org/obo/OBI_0200089,,http://purl.obolibrary.org/obo/OBI_0000791,,FDR correction method,,,,,,,,,,,,,,,"The false discovery rate is a  data transformation used in multiple hypothesis testing to correct for multiple comparisons. It controls the expected proportion of incorrectly rejected null hypotheses (type I errors) in a list of rejected hypotheses. It is a less conservative comparison procedure with greater power than familywise error rate (FWER) control, at a cost of increasing the likelihood of obtaining type I errors. .","Dudoit, Sandrine and van der Laan, Mark J. (2008) Multiple Testing Procedures with Applications to Genomics.  New York: Springer , p. 21 and http://www.wikidoc.org/index.php/False_discovery_rate",,,,,"2011-03-31: [PRS]. 
creating a defined class by specifying the necessary output of dt
allows correct classification of FDR dt",false discovery rate correction method,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000175,,,,OBI:0200163,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,false discovery rate correction method,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra|Monnie McGee,,
http://purl.obolibrary.org/obo/PR_000014060,ribonuclease T2,,A protein that is a translation product of the human RNASET2 gene or a 1:1 ortholog thereof.,false,,,http://purl.obolibrary.org/obo/PR_000000001,,,,,,,,,,,,,,,,,,,A protein that is a translation product of the human RNASET2 gene or a 1:1 ortholog thereof.,,,,,,,ribonuclease T2,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PR:000014060,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pr.owl,,,,,,,,,,,,,,,,,,,ribonuclease T2,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000490,cation exchange column,,A cation exchange column is a chromatography column that is used in cation exchange chromatography.,false,,,http://purl.obolibrary.org/obo/OBI_0000560,,,,,,,,,,,,,,,,,,,A cation exchange column is a chromatography column that is used in cation exchange chromatography.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01096,,,,,,cation exchange column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000490,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cation exchange column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0400137,cytometer,,A cytometer is an instrument for counting and measuring cells.,false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,A cytometer is an instrument for counting and measuring cells.,http://medical.merriam-webster.com/medical/cytometer,,,,,,cytometer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400137,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cytometer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0000736,single fragment library,fragment library,"is a collection of short tags from DNA fragments, are extracted and covalently linked as single tag constructs",false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,fragment library,,,,,,,,,,,,,,,"is a collection of short tags from DNA fragments, are extracted and covalently linked as single tag constructs",,,,,,,single fragment library,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000736,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,single fragment library,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000932,material separation device,,A device with a separation function realized in a planed process,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A device with a separation function realized in a planed process,,,,,,,material separation device,,flow cytometer,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000932,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,material separation device,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0002001,Illumina HiSeq 2000,HiSeq 2000,"A DNA sequencer which is manufactured by the Illumina corporation, with two flow cells and a throughput of up to 55 Gb per day. Built upon sequencing by synthesis technology, the machine is optimized for generation of data for multiple samples in a single run.",false,,,http://purl.obolibrary.org/obo/OBI_0400103,,,,HiSeq 2000,,,,,,,,,,,,,,,"A DNA sequencer which is manufactured by the Illumina corporation, with two flow cells and a throughput of up to 55 Gb per day. Built upon sequencing by synthesis technology, the machine is optimized for generation of data for multiple samples in a single run.",http://res.illumina.com/documents/products/datasheets/datasheet_hiseq_systems.pdf,,,,,,Illumina HiSeq 2000,,"Wang J, Qi J, Zhao H, He S, Zhang Y, Wei S, Zhao F. Metagenomic sequencing reveals microbiota and its functional potential associated with periodontal disease. Sci Rep. 2013 May;3:1843. PMID:23673380",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002001,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Illumina HiSeq 2000,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"PERSON: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001697,in vivo assay measuring B cell epitope specific treatment of disease,decreased disease|in vivo assay,An efficacy of B cell epitope intervention experiment that detects a decrease in disease.,false,,,http://purl.obolibrary.org/obo/OBI_0001698,,,,,,,,,,,,,,,,,,,An efficacy of B cell epitope intervention experiment that detects a decrease in disease.,IEDB,,,,,,in vivo assay measuring B cell epitope specific treatment of disease,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001697,,,,,,,,,,,,,,,,,,,,,,,,decreased disease|in vivo assay,,,,,,,,,,,,,,,,,,,,,,in vivo assay measuring B cell epitope specific treatment of disease,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000715,animal care protocol,,An animal care protocol is a protocol which specifies the environment in which animals are being kept in captivity for research purposes,false,,,http://purl.obolibrary.org/obo/OBI_0000272,,,,,,,,,,,,,,,,,,,An animal care protocol is a protocol which specifies the environment in which animals are being kept in captivity for research purposes,Bjoern Peters,,,,,,animal care protocol,,"Keeping mice in the UCSD animals facility at 20 - 25 degrees celsius, in cages of 4 animals each and providing food twice daily.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000715,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,animal care protocol,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001265,FWER adjusted p-value,,A quantitative confidence value resulting from a multiple testing error correction method which adjusts the p-value used as input to control for Type I error in the context of multiple pairwise tests,false,,,http://purl.obolibrary.org/obo/OBI_0000071,,,,,,,,,,,,,,,,,,,A quantitative confidence value resulting from a multiple testing error correction method which adjusts the p-value used as input to control for Type I error in the context of multiple pairwise tests,adapted from wikipedia (http://en.wikipedia.org/wiki/Familywise_error_rate) ,,,,,,FWER adjusted p-value,,http://ugrad.stat.ubc.ca/R/library/LPE/html/mt.rawp2adjp.html,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001265,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,FWER adjusted p-value,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERS:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001260,ELISA measuring epitope specific interleukin-3 production by T cells,IL-3 release|ELISA,An assay of epitope specific interleukin-3 production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001406,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-3 production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific interleukin-3 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001260,,,,,,,,,,,,,,,,,,,,,,,,IL-3 release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific interleukin-3 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0200117,mode calculation,,A mode calculation is a descriptive statistics calculation in which the mode is calculated which is the most common value in a data set. It is most often used as a measure of center for discrete data.,false,,,http://purl.obolibrary.org/obo/OBI_0200184|http://purl.obolibrary.org/obo/OBI_0200181,,http://purl.obolibrary.org/obo/OBI_0200078,,,,,,,,,,,,,,,From Monnie's file comments - need to add center_calculation role but it doesn't exist yet - (editor note added by James Jan 2008),,A mode calculation is a descriptive statistics calculation in which the mode is calculated which is the most common value in a data set. It is most often used as a measure of center for discrete data.,PERSON: James Malone|PERSON: Monnie McGee,,,,,,mode calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200117,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,mode calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Monnie McGee,,
http://purl.obolibrary.org/obo/OBI_0600037,cell culture splitting,cell culture passaging,"The act of taking part of a homogeneous cell culture and creating one or more additional separate cultures of similar qualities. input: cell_culture, output cell_culture min cardinality 2. part of cell culturing|An active cell culture is typically split when it has grown to confluence in its culture dish.  Cell culture splitting of a cell culture sample results in an increase in its passage number, which measures how long a sample has been propagated in vitro, and therefore how many selective or genetic changes it is likely to have undergone.",false,,,http://purl.obolibrary.org/obo/OBI_0600014,,http://purl.obolibrary.org/obo/OBI_0000678,,cell culture passaging,,,,,,,,,,,,,,,"The act of taking part of a homogeneous cell culture and creating one or more additional separate cultures of similar qualities. input: cell_culture, output cell_culture min cardinality 2. part of cell culturing",OBI branch derived,,,,,,cell culture splitting,,"The act of taking a cell culture of high density, counting the cells, removing part of the cells, and re-seeding a select number of the cells into new flasks with fresh tissue culture media.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100060,http://purl.obolibrary.org/obo/OBI_0100060,,,OBI:0600037,,,,,,,,,,,,,,,,,,"An active cell culture is typically split when it has grown to confluence in its culture dish.  Cell culture splitting of a cell culture sample results in an increase in its passage number, which measures how long a sample has been propagated in vitro, and therefore how many selective or genetic changes it is likely to have undergone.",,,,,,,,,,,,,,,,,,,,,,,,,,,,cell culture splitting,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/CL_0000578,experimentally modified cell in vitro,,A cell in vitro that has undergone physical changes as a consequence of a deliberate and specific experimental procedure.,false,,,http://purl.obolibrary.org/obo/CL_0000000|http://purl.obolibrary.org/obo/OBI_0000047,,,,,,,,,,,,,,,,,,,A cell in vitro that has undergone physical changes as a consequence of a deliberate and specific experimental procedure.,,,,,,,experimentally modified cell in vitro,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CL:0000578,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/cl.owl,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000094,,,experimentally modified cell in vitro,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001058,microplate reader,,"A measurement device that detects biological, chemical or physical events of samples in microtiter plates.",false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,"A measurement device that detects biological, chemical or physical events of samples in microtiter plates.",http://en.wikipedia.org/wiki/Plate_reader,,,,,,microplate reader,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001058,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,microplate reader,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0001311,X-ray crystallography assay determining the 3D structure of a T cell epitope:MHC:TCR complex,3D structure|x-ray crystallography|angstroms,A T cell epitope 3D structure determination assay that uses an X-ray crystallography assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001999,,,,,,,,,,,,,,,,,,,A T cell epitope 3D structure determination assay that uses an X-ray crystallography assay.,IEDB,,,,,,X-ray crystallography assay determining the 3D structure of a T cell epitope:MHC:TCR complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001311,,,,,,,,,,,,,,,,,,,,,,,,3D structure|x-ray crystallography|angstroms,,,,,,,,,,,,,,,,,,,,,,X-ray crystallography assay determining the 3D structure of a T cell epitope:MHC:TCR complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0002041,self-transcribing active regulatory region sequencing assay,self-transcribing active regulatory region sequencing|STARR-seq assay|STARR-seq,"A RNA-seq assay to identify the sequences that act as transcriptional enhancers in a direct, quantitative, and genome-wide manner from sheared genomic DNA.",false,,,http://purl.obolibrary.org/obo/OBI_0001271,,,,self-transcribing active regulatory region sequencing|STARR-seq assay|STARR-seq,,,,,,,,,,,,,,,"A RNA-seq assay to identify the sequences that act as transcriptional enhancers in a direct, quantitative, and genome-wide manner from sheared genomic DNA.","Arnold et al. (January 2013). ""Genome-Wide Quantitative Enhancer Activity Maps Identified by STARR-seq"". Science 339 (6123): 1074-7.",,,,,,self-transcribing active regulatory region sequencing assay,,"Bohla et al., (September 2014). ""A functional insulator screen identifies NURF and dREAM components to be required for enhancer-blocking."" PLoS One 9(9):e107765. doi: 10.1371/journal.pone.0107765.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002041,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,self-transcribing active regulatory region sequencing assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001785,intracellular cytokine staining assay measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells,CCL9/MIP-1g release|ICS,An assay of epitope specific macrophage inflammatory protein-1 gamma production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001456,,,,,,,,,,,,,,,,,,,An assay of epitope specific macrophage inflammatory protein-1 gamma production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001785,,,,,,,,,,,,,,,,,,,,,,,,CCL9/MIP-1g release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001749,intracellular cytokine staining assay measuring epitope specific interferon-beta production by T cells,IFNb release|ICS,An assay of epitope specific interferon-beta production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001390,,,,,,,,,,,,,,,,,,,An assay of epitope specific interferon-beta production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific interferon-beta production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001749,,,,,,,,,,,,,,,,,,,,,,,,IFNb release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific interferon-beta production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000516,NMR probe,,"Part of an NMR instrument that detects the signals emitted from a sample. No single probe can perform the full range of experiments, and probes that are designed to perform more than one type of measurement usually suffer from performance compromises. The probe represents a rather fragile single point of failure that can render an NMR system completely unusable if the probe is dropped or otherwise damaged. Probes are usually characterised by Sample diameter and Frequency.\n  alt The instrument that transmits and receives radiofrequency to and from the NMR sample.",false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,NMR instrument,,"Part of an NMR instrument that detects the signals emitted from a sample. No single probe can perform the full range of experiments, and probes that are designed to perform more than one type of measurement usually suffer from performance compromises. The probe represents a rather fragile single point of failure that can render an NMR system completely unusable if the probe is dropped or otherwise damaged. Probes are usually characterised by Sample diameter and Frequency.\n  alt The instrument that transmits and receives radiofrequency to and from the NMR sample.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400014,,,,,,NMR probe,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000566,OBI:0000516,http://purl.obolibrary.org/obo/OBI_0000566,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NMR probe,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000588,flame photometric detector,FPD,"The determination of sulfur or phosphorus containing compounds is the job of the flame photometric detector (FPD). This device uses the chemiluminescent reactions of these compounds in a hydrogen/air flame as a source of analytical information that is relatively specific for substances containing these two kinds of atoms. The emitting species for sulfur compounds is excited S2. The lambda max for emission of excited S2 is approximately 394 nm. The emitter for phosphorus compounds in the flame is excited HPO (lambda max = doublet 510-526 nm). In order to selectively detect one or the other family of compounds as it elutes from the GC column, an interference filter is used between the flame and the photomultiplier tube (PMT) to isolate the appropriate emission band. The drawback here being that the filter must be exchanged between chromatographic runs if the other family of compounds is to be detected.",false,,,http://purl.obolibrary.org/obo/OBI_0000637,,,,FPD,,,,,,,,,,,,,,,"The determination of sulfur or phosphorus containing compounds is the job of the flame photometric detector (FPD). This device uses the chemiluminescent reactions of these compounds in a hydrogen/air flame as a source of analytical information that is relatively specific for substances containing these two kinds of atoms. The emitting species for sulfur compounds is excited S2. The lambda max for emission of excited S2 is approximately 394 nm. The emitter for phosphorus compounds in the flame is excited HPO (lambda max = doublet 510-526 nm). In order to selectively detect one or the other family of compounds as it elutes from the GC column, an interference filter is used between the flame and the photomultiplier tube (PMT) to isolate the appropriate emission band. The drawback here being that the filter must be exchanged between chromatographic runs if the other family of compounds is to be detected.",WEB:<http://www.shsu.edu/~chemistry/FPD/FPD.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01091,,,,,,flame photometric detector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000588,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,flame photometric detector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000556,isocratic pump system,,A pump system optimized for isocratic chromatography.,false,,,http://purl.obolibrary.org/obo/OBI_0000589,,,,,,,,,,,,,,,,,,,A pump system optimized for isocratic chromatography.,WEB:<http://www.buchi.com/Isocratic-Pump-System.253.0.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01049,,,,,,isocratic pump system,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000556,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,isocratic pump system,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000465,organic acid column,,An organic acid column is a chromatography column which enables (reversed-phase) separation of hydrophilic aliphatic and aromatic organic acids with UV detection. Organic acid columns allow retention of polar and apolar organic acids and are hydrolysis resistant.,false,,,http://purl.obolibrary.org/obo/OBI_0000038,,,,,,,,,,,,,,,,,,,An organic acid column is a chromatography column which enables (reversed-phase) separation of hydrophilic aliphatic and aromatic organic acids with UV detection. Organic acid columns allow retention of polar and apolar organic acids and are hydrolysis resistant.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01099,,,,,,organic acid column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000465,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,organic acid column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000249,technical replicate role,technical replicate,technical replicate role is realized when two portions from one evaluant are used in replicate runs of an assay,false,,,http://purl.obolibrary.org/obo/OBI_0000220,,,,technical replicate,,,,,,,,,,,,,,,technical replicate role is realized when two portions from one evaluant are used in replicate runs of an assay,,,,,,,technical replicate role,,Aliquots of a tissue subjected to parallel assays,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000249,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,technical replicate role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0001896,investigation assay specification,Project Method,A plan specification which indicates the assay type used to obtain data.,false,,,http://purl.obolibrary.org/obo/IAO_0000104,,,,,,,,,,,,,,,,,,,A plan specification which indicates the assay type used to obtain data.,NIAID GSCID-BRC metadata working group,,,,,,investigation assay specification,,"Some examples of Project Method are Sequence, Array, Mass Spectrometry",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0500000,OBI:0001896,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,investigation assay specification,,,,,,Project Method,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NIAID GSCID-BRC,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0200170,averaging data transformation,,An averaging data transformation is a data transformation that has objective averaging.,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,An averaging data transformation is a data transformation that has objective averaging.,PERSON: James Malone,,,,,,averaging data transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200170,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,averaging data transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/OBI_0000885,secondary structure of sequence macromolecule,,"A quality inhering in a molecule that refers to general three-dimensional form of local segments of biopolymers such as proteins and nucleic acids (DNA/RNA). It does not, however, describe specific atomic positions in three-dimensional space, which are considered to be tertiary structure.
Secondary structure was introduced by Kaj Ulrik Linderstrøm-Lang in the 1952 Lane medical lectures at Stanford.",false,,,http://purl.obolibrary.org/obo/PATO_0001237,,,,,,,,,,,,,,,,,,,"A quality inhering in a molecule that refers to general three-dimensional form of local segments of biopolymers such as proteins and nucleic acids (DNA/RNA). It does not, however, describe specific atomic positions in three-dimensional space, which are considered to be tertiary structure.
Secondary structure was introduced by Kaj Ulrik Linderstrøm-Lang in the 1952 Lane medical lectures at Stanford.",Wikipedia,,,,,2010-01-31: Philippe Rocca-Serra: This is a placeholder to allow work on 'nucleic acid mapping assay' in collaboration with RNAOntology group. Need to liaise with SO,secondary structure of sequence macromolecule,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000002,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000885,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,secondary structure of sequence macromolecule,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000211,proxy respondent role,proxy respondent,Proxy respondent is a worker role of describing patient's symptoms or condition to medical personnel,false,,,http://purl.obolibrary.org/obo/OBI_0000116,,,,proxy respondent,,,,,,,,,,,,,,,Proxy respondent is a worker role of describing patient's symptoms or condition to medical personnel,,,,,,,proxy respondent role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000211,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,proxy respondent role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0001613,purified MHC competitive binding assay measuring half maximal inhibitory concentration [IC50] of a MHC:ligand complex using fluorescence detection,half maximal inhibitory concentration (IC50)|purified MHC/competitive/fluorescence|nM,A purified MHC ligand binding half maximal inhibitory concentration (IC50) determination assay that uses fluorescence detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation.,false,,,http://purl.obolibrary.org/obo/OBI_0001499|http://purl.obolibrary.org/obo/OBI_0001992,,,,,,,,,,,,,,,,,,,A purified MHC ligand binding half maximal inhibitory concentration (IC50) determination assay that uses fluorescence detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation.,IEDB,,,,,,purified MHC competitive binding assay measuring half maximal inhibitory concentration [IC50] of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001613,,,,,,,,,,,,,,,,,,,,,,,,half maximal inhibitory concentration (IC50)|purified MHC/competitive/fluorescence|nM,,,,,,,,,,,,,,,,,,,,,,purified MHC competitive binding assay measuring half maximal inhibitory concentration [IC50] of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000730,pyrosequencing,,"is a DNA sequencing which allows sequencing of a single strand of DNA by synthesizing the complementary strand along it, one base pair at a time, and detecting which base was actually added at each step. The template DNA is immobilized, and solutions of A, C, G, and T nucleotides are added and removed after the reaction, sequentially. Light is produced only when the nucleotide solution complements the first unpaired base of the template. The sequence of solutions which produce chemiluminescent signals allows the determination of the sequence of the template.

ssDNA template is hybridized to a sequencing primer and incubated with the enzymes DNA polymerase, ATP sulfurylase, luciferase and apyrase, and with the substrates adenosine 5-prime phosphosulfate (APS) and luciferin.",false,,,http://purl.obolibrary.org/obo/OBI_0000734,,,,,,,,,,,,,,,,,,,"is a DNA sequencing which allows sequencing of a single strand of DNA by synthesizing the complementary strand along it, one base pair at a time, and detecting which base was actually added at each step. The template DNA is immobilized, and solutions of A, C, G, and T nucleotides are added and removed after the reaction, sequentially. Light is produced only when the nucleotide solution complements the first unpaired base of the template. The sequence of solutions which produce chemiluminescent signals allows the determination of the sequence of the template.

ssDNA template is hybridized to a sequencing primer and incubated with the enzymes DNA polymerase, ATP sulfurylase, luciferase and apyrase, and with the substrates adenosine 5-prime phosphosulfate (APS) and luciferin.",Wikipedia (http://en.wikipedia.org/wiki/Pyrosequencing) and Roche 454 life science web site,,,,,,pyrosequencing,,"Pyrosequencing sheds light on DNA sequencing.
PMID: 1115661.  Ronaghi M. Genome Res. 2001 Jan;11(1):3-11. Review.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000730,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,pyrosequencing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001989,purified MHC competitive binding assay measuring equilibrium dissociation constant [KD] of a MHC:ligand complex using radioactivity detection,dissociation constant KD|purified MHC/direct/radioactivity|nM,A purified MHC ligand binding equilibrium dissociation constant (KD) determination assay that uses radioactivity detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation.,false,,,http://purl.obolibrary.org/obo/OBI_0001988|http://purl.obolibrary.org/obo/OBI_0001491,,,,,,,,,,,,,,,,,,,A purified MHC ligand binding equilibrium dissociation constant (KD) determination assay that uses radioactivity detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation.,IEDB,,,,,,purified MHC competitive binding assay measuring equilibrium dissociation constant [KD] of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001989,,,,,,,,,,,,,,,,,,,,,,,,dissociation constant KD|purified MHC/direct/radioactivity|nM,,,,,,,,,,,,,,,,,,,,,,purified MHC competitive binding assay measuring equilibrium dissociation constant [KD] of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001692,in vivo assay measuring B cell epitope specific protection from fertility,protection from fertility|in vivo assay,An efficacy of B cell epitope intervention experiment that uses a protection from challenge in vivo intervention experiment based on reduction of fertility.,false,,,http://purl.obolibrary.org/obo/OBI_0001698,,,,,,,,,,,,,,,,,,,An efficacy of B cell epitope intervention experiment that uses a protection from challenge in vivo intervention experiment based on reduction of fertility.,IEDB,,,,,,in vivo assay measuring B cell epitope specific protection from fertility,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001980,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100026,,,,OBI:0001692,,,,,,,,,,,,,,,,,,,,,,,,protection from fertility|in vivo assay,,,,,,,,,,,,,,,,,,,,,,in vivo assay measuring B cell epitope specific protection from fertility,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, James Overton, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001407,biological activity assay measuring epitope specific T cell activation,activation|biological activity,A T cell epitope dependent biological activity assay that detects T cell activation.,false,,,http://purl.obolibrary.org/obo/OBI_0002055,,,,,,,,,,,,,,,,,,,A T cell epitope dependent biological activity assay that detects T cell activation.,IEDB,,,,,,biological activity assay measuring epitope specific T cell activation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001407,,,,,,,,,,,,,,,,,,,,,,,,activation|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific T cell activation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001200,genotyping by high throughput sequencing design,,"A study design that classifies an individual or group of individuals on the basis of alleles, haplotypes, SNPs using high througput sequencing techniques.",false,,,http://purl.obolibrary.org/obo/OBI_0001444,,,,,,,,,,,,,,,,,,,"A study design that classifies an individual or group of individuals on the basis of alleles, haplotypes, SNPs using high througput sequencing techniques.",MO_560 genotyping_design,,,,,,genotyping by high throughput sequencing design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001200,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,genotyping by high throughput sequencing design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001398,protein and DNA interaction identification objective,,A sequence feature identification objective that aims to characterize the interactions between protein and DNA which includes identification of transcription factor binding sites.,false,,,http://purl.obolibrary.org/obo/OBI_0000113,,,,,,,,,,,,,,,,,,,A sequence feature identification objective that aims to characterize the interactions between protein and DNA which includes identification of transcription factor binding sites.,MO_933 binding_site_identification_design,,,,,,protein and DNA interaction identification objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001398,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,protein and DNA interaction identification objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001454,pathogenicity design,,"A study design in which an infective agent such as a bacterium, virus, protozoan, fungus etc. infects a host organism(s) and the infective agent is assayed.",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A study design in which an infective agent such as a bacterium, virus, protozoan, fungus etc. infects a host organism(s) and the infective agent is assayed.",MO_807 pathogenicity_design,,,,,,pathogenicity design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000015,,,,,,,,,,,,,,,,OBI:0001454,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,pathogenicity design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0302886,centrifugation,,centrifugation is a process separating molecules by size or density using centrifugal forces generated by a spinning rotor. G-forces of several hundred thousand times gravity are generated in ultracentrifugation,false,,,http://purl.obolibrary.org/obo/OBI_0600014,,http://purl.obolibrary.org/obo/OBI_0000681,,,,,,,,,,,,,,,,,centrifugation is a process separating molecules by size or density using centrifugal forces generated by a spinning rotor. G-forces of several hundred thousand times gravity are generated in ultracentrifugation,adapted from http://www.fao.org/DOCREP/003/X3910E/X3910E06.htm,,,,,,centrifugation,,PMID: 18428461.Purification of oligodendrocytes and their progenitors using immunomagnetic separation and Percoll gradient centrifugation. Curr Protoc Neurosci. 2001 May;Chapter 3:Unit 3.12.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0400106,,,,,,,,,,,,,,,OBI:0302886,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,centrifugation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000512,isolation of cell population,,a process in which a population of cells with certain characteristics is isolated from a larger population,false,,,http://purl.obolibrary.org/obo/OBI_0600014,,http://purl.obolibrary.org/obo/OBI_0000681,,,,,,,,,,,,,,,,,a process in which a population of cells with certain characteristics is isolated from a larger population,,,,,,,isolation of cell population,,removing CD4+ cells from PBMCs using magnetic beads.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0100060,http://purl.obolibrary.org/obo/OBI_0100060,,,OBI:0000512,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,isolation of cell population,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0001841,intracellular cytokine staining assay measuring epitope specific interleukin-1 beta production by T cells,IL-1b release|ICS,An assay of epitope specific interleukin-1 beta production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001449,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-1 beta production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-1 beta production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001841,,,,,,,,,,,,,,,,,,,,,,,,IL-1b release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-1 beta production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001520,cell bound MHC competitive binding assay measuring half maximal inhibitory concentration [IC50] of a MHC:ligand complex using fluorescence detection,half maximal inhibitory concentration (IC50)|cellular MHC/competitive/fluorescence|nM,A cell bound MHC ligand binding half maximal inhibitory concentration (IC50) determination assay that uses fluorescence detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation.,false,,,http://purl.obolibrary.org/obo/OBI_0001499|http://purl.obolibrary.org/obo/OBI_0001992,,,,,,,,,,,,,,,,,,,A cell bound MHC ligand binding half maximal inhibitory concentration (IC50) determination assay that uses fluorescence detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation.,IEDB,,,,,,cell bound MHC competitive binding assay measuring half maximal inhibitory concentration [IC50] of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001520,,,,,,,,,,,,,,,,,,,,,,,,half maximal inhibitory concentration (IC50)|cellular MHC/competitive/fluorescence|nM,,,,,,,,,,,,,,,,,,,,,,cell bound MHC competitive binding assay measuring half maximal inhibitory concentration [IC50] of a MHC:ligand complex using fluorescence detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000089,role of regulator of chemical manufacturer,regulator of chemical manufacture,a regulator involved with making and enforcing legislation and governmental orders relevant to chemical manufacture,false,,,http://purl.obolibrary.org/obo/OBI_0000014,,,,regulator of chemical manufacture,,,,,,,,,,,,,,,a regulator involved with making and enforcing legislation and governmental orders relevant to chemical manufacture,OBI,,,,,,role of regulator of chemical manufacturer,,"EPA; John Mollison is the registrar of chemical products in Tasmania, the body that administers the Act that regulates chemical use in that State. http://www.abc.net.au/rn/science/earth/stories/s1160346.htm",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000089,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,role of regulator of chemical manufacturer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0001171,half life datum (t 1/2),t 1/2,The time it takes for 50% of a class of stochastic processes to occur. ,false,,,http://purl.obolibrary.org/obo/IAO_0000416,,,,t 1/2,,,,,,,,,,,,,,,The time it takes for 50% of a class of stochastic processes to occur. ,Bjoern Peters,,,,,,half life datum (t 1/2),,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,http://purl.obolibrary.org/obo/UO_0000003,,,,,,,,,,,,,,,,,,,,,OBI:0001171,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,half life datum (t 1/2),,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000252,cohort role,,a cohort role is a biological replicate role played by a group of study participants who share a common characteristic of interest to the study.,false,,,http://purl.obolibrary.org/obo/OBI_0000198,,,,,,,,,,,,,,,,,,,a cohort role is a biological replicate role played by a group of study participants who share a common characteristic of interest to the study.,"WEB:http://www.thebody.org/content/treat/art2612.html # a group of individuals in a study who share a demographic, clinical, or other statistical characteristic (eg, age, study site).|WEB:http://www.uhhospitals.org/tabid/591/Default.aspx # A cohort is a group of people with a common characteristic that is studied over a period of time as part of a scientific or medical investigation.|WEB:http://www.sceoc.com/glossaryofterms/ # a group of individuals having a statistical factor (as age or class membership) in common in a demographic study, such as a cohort of students.",,,,,,cohort role,,"In statistics and demography, a cohort is a group of subjects - most often humans from a given population - defined by experiencing an event (typically birth) in a particular time span.  Wikipedia ""cohort"", Feb 29 2008",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000252,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cohort role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0000649,data set of features,,A data set that is produced as the output of a descriptive statistical calculation data transformation and consists of producing a data set that represents one or more features of interest about the input data set.,false,,,http://purl.obolibrary.org/obo/IAO_0000100,,,,,,,,,,,,,,,,,,,A data set that is produced as the output of a descriptive statistical calculation data transformation and consists of producing a data set that represents one or more features of interest about the input data set.,,,,,,,data set of features,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000649,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,data set of features,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: James Malone|PERSON: Monnie McGee,,
http://purl.obolibrary.org/obo/OBI_0400146,multispectral imaging flow cytometer,MIFC,"A multispectral_imaging_flow_cytometer is an instrument which combines quantitative image analysis and flow cytometry in a single platform. It measures the amount, location and movement of molecules on, in, or between cells, and  the location and co-localization of multiple markers on or in cells. It can also quantitate morphologically distinct cell subpopulations.",false,,,http://purl.obolibrary.org/obo/OBI_0000398,,,,MIFC,,,,,,,,,,,,,,,"A multispectral_imaging_flow_cytometer is an instrument which combines quantitative image analysis and flow cytometry in a single platform. It measures the amount, location and movement of molecules on, in, or between cells, and  the location and co-localization of multiple markers on or in cells. It can also quantitate morphologically distinct cell subpopulations.",http://www.amnis.com/,,,,,,multispectral imaging flow cytometer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/OBI_0000397|http://purl.obolibrary.org/obo/OBI_0000392,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0400044,,,,,,,,,,,,,,,,OBI:0400146,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,multispectral imaging flow cytometer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0000369,magnify function,,A magnify function is a function to increase the size of a transmitted object image through the precise arrangement of energy diffraction elements along an imaging path.,false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,A magnify function is a function to increase the size of a transmitted object image through the precise arrangement of energy diffraction elements along an imaging path.,,,,,,,magnify function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000369,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,magnify function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bill Bug|Daniel Schober|Frank Gibson|Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0000668,error correction data transformation,,"An error correction data transformation is a data transformation that has the objective of error correction, where the aim is to remove (correct for) erroneous contributions from the input to the data transformation.",false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,"An error correction data transformation is a data transformation that has the objective of error correction, where the aim is to remove (correct for) erroneous contributions from the input to the data transformation.",EDITORS,,,,,,error correction data transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000668,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,error correction data transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Monnie McGee,,
http://purl.obolibrary.org/obo/GO_0009987,cellular process,,"Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.",false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,"Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.",,,,,,,cellular process,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0009987,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,cellular process,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0500026,eligibility criterion,eligibility rule,"an eligibility criterion (rule) is_a selection criterion which 
defines and states the requirements (positive or negative) for an entity to be considered as suitable for a given task or participation in a process.
",false,,,http://purl.obolibrary.org/obo/OBI_0001755,,,,eligibility rule,,,,,,,,,,,,,,,"an eligibility criterion (rule) is_a selection criterion which 
defines and states the requirements (positive or negative) for an entity to be considered as suitable for a given task or participation in a process.
",Adapted from Clinical Research Glossary Version 4.0 CDICS glossary group,,,,,,eligibility criterion,,"PMID: 17579629 -Eligibility criteria included: untreated ED-SCLC; age >/=70 and performance status 0-2, or age <70 and PS 3.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500026,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,eligibility criterion,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000892,Southern blot analysis,Southern blot,"Southern blot analysis is a an assay used in molecular biology to assert the presence/absence status  of a specific DNA sequence in DNA samples. DNA samples to be assayed are first digested by restriction enzymes, fragments are then resolved by gel electrophoresis following by a blotting ensuring transfer to  nitrocellulose or nylon membrane. Immobilization of DNA fragments to the membrane is achieved by UV crosslinking and/or baking. Probes raised against the specific sequences are then hybridized to the membrane.  Detection of  hybridization signals is carried out by immunofluorescence or radioactivity measurements using photographic films or digital imaging devices such as Phosphor Imager.",false,,,http://purl.obolibrary.org/obo/OBI_0000443,,http://purl.obolibrary.org/obo/OBI_0000441,,Southern blot,,,,,,,,,,,,,,,"Southern blot analysis is a an assay used in molecular biology to assert the presence/absence status  of a specific DNA sequence in DNA samples. DNA samples to be assayed are first digested by restriction enzymes, fragments are then resolved by gel electrophoresis following by a blotting ensuring transfer to  nitrocellulose or nylon membrane. Immobilization of DNA fragments to the membrane is achieved by UV crosslinking and/or baking. Probes raised against the specific sequences are then hybridized to the membrane.  Detection of  hybridization signals is carried out by immunofluorescence or radioactivity measurements using photographic films or digital imaging devices such as Phosphor Imager.",OBI & Wikipedia,,,,,"2010-01-31: Philippe Rocca-Serra:
need extra work on 'labeled probe'|2010-01-31: Philippe Rocca-Serra: 
departure from naming convention as the assay is named after Edwin Southern.",Southern blot analysis,,"PMID: 9452032. Germline mutations detected in the von Hippel-Lindau disease tumor suppressor gene by Southern blot and direct genomic DNA sequencing. Li C, Weber G, Ekman P, Lagercrantz J, Norlen BJ, Akerström G, Nordenskjöld M, Bergerheim US. Hum Mutat. 1998;Suppl 1:S31-3.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000892,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Southern blot analysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/NCBITaxon_44689,Dictyostelium discoideum,,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_2759,,,,,,,,,,,,,,,,,,,,,,,,,,Dictyostelium discoideum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:44689,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Dictyostelium discoideum,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001967,multiplexing sequence identifier,,A multiplexing sequence identifier is a nucleic acid sequence which is used in a ligation step of library preparation process to allow pooling of samples while maintaining ability to identify individual source material and creation of a multiplexed library,false,,,http://purl.obolibrary.org/obo/CHEBI_16991,,,,,,,,,,,,,,,,,,,A multiplexing sequence identifier is a nucleic acid sequence which is used in a ligation step of library preparation process to allow pooling of samples while maintaining ability to identify individual source material and creation of a multiplexed library,OBI,,,,,,multiplexing sequence identifier,,We designed primers specifically to amplify protease and reverse transcriptase from Brazilian HIV subtypes and developed a multiplexing scheme using multiplex identifier tags to minimize cost while providing more robust data than traditional genotyping techniques. in http://www.ncbi.nlm.nih.gov/pubmed/22574170,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001967,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,multiplexing sequence identifier,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0002069,ELISPOT assay measuring epitope specific perforin release by T cells,perforin release|ELISPOT,A T cell epitope specific perforin release assay that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001497,,,,,,,,,,,,,,,,,,,A T cell epitope specific perforin release assay that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific perforin release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002069,,,,,,,,,,,,,,,,,,,,,,,,perforin release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific perforin release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0400066,logarithmic voltage amplifier,,"A logarithmic voltage amplifier is an analog electronic circuit that puts out a voltage or current proportional to the voltage or current at its input, with logarithmic proportionality. In an analog system, the logarithmic voltage amplifier is used to present parameters with a high dynamic range on a more useful scale.",false,,,http://purl.obolibrary.org/obo/OBI_0400101,,,,,,,,,,,,,,,,,,,"A logarithmic voltage amplifier is an analog electronic circuit that puts out a voltage or current proportional to the voltage or current at its input, with logarithmic proportionality. In an analog system, the logarithmic voltage amplifier is used to present parameters with a high dynamic range on a more useful scale.","Practical Flow Cytometry 4th Edition, Howard Shapiro, ISBN-10: 0471411256, ISBN-13: 978-0471411253",,,,,,logarithmic voltage amplifier,,"HLVA-100 logarithmic voltage amplifier developed by FEMTO Messtechnik, GmbH",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400066,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,logarithmic voltage amplifier,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0001840,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-17A production by T cells,IL-17A release|RNA/DNA detection,A T cell epitope specific interleukin-17A production assay that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001773|http://purl.obolibrary.org/obo/OBI_0001291,,,,,,,,,,,,,,,,,,,A T cell epitope specific interleukin-17A production assay that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-17A production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001840,,,,,,,,,,,,,,,,,,,,,,,,IL-17A release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-17A production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001850,transcript analysis by paired-end tag sequencing,RNA-PET assay|RNA-PET,"An assay that incorporates Paired-End Tags and sequencing technology to determine transcripts, gene structures, and gene expressions.",false,,,http://purl.obolibrary.org/obo/OBI_0600047|http://purl.obolibrary.org/obo/OBI_0000424,,http://purl.obolibrary.org/obo/OBI_0001331,,RNA-PET assay|RNA-PET,,,,,,,,,,,,,,,"An assay that incorporates Paired-End Tags and sequencing technology to determine transcripts, gene structures, and gene expressions.","Ruan, et al. Genome wide full-length transcript analysis using 5' and 3' paired-end-tag next generation sequencing (RNA-PET). Methods Mol Biol. 2012;809:535-62. [PMID:22113299]",,,,,,transcript analysis by paired-end tag sequencing,,"Ruan, et al. Genome wide full-length transcript analysis using 5' and 3' paired-end-tag next generation sequencing (RNA-PET). Methods Mol Biol. 2012;809:535-62. [PMID:22113299]",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001852|http://purl.obolibrary.org/obo/OBI_0001177,http://purl.obolibrary.org/obo/OBI_0400103,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0001573,,,OBI:0001850,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,transcript analysis by paired-end tag sequencing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0002063,cytometric bead array assay measuring epitope specific granzyme A release by T cells,granzyme A release|cytometric bead array,A T cell epitope specific granzyme A release assay that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001809,,,,,,,,,,,,,,,,,,,A T cell epitope specific granzyme A release assay that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific granzyme A release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002063,,,,,,,,,,,,,,,,,,,,,,,,granzyme A release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific granzyme A release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001331,transcription profiling identification objective,,A molecular feature identification objective that aims to characterize the abundance of transcripts,false,,,http://purl.obolibrary.org/obo/OBI_0000131,,,,,,,,,,,,,,,,,,,A molecular feature identification objective that aims to characterize the abundance of transcripts,Group: Penn Group,,,,,,transcription profiling identification objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001331,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,transcription profiling identification objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001199,in vivo design,,"A study design that is conducted entirely in a living organism, e.g. a compound treatment in a mouse model.",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A study design that is conducted entirely in a living organism, e.g. a compound treatment in a mouse model.",MO_454 in_vivo_design,,,,,,in vivo design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001199,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,in vivo design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0000083,electronic case report tabulation,,An electronic case report tabulation is a digital document containing tabular data about multiple trial participants which is part of a clinical regulatory submission.  An eCRT has the property that it can be audited and compliant with requirements of 21 CFR Part 11  and has format suited to review by regulators.,false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,,,,,,,,,,,,,,,,An electronic case report tabulation is a digital document containing tabular data about multiple trial participants which is part of a clinical regulatory submission.  An eCRT has the property that it can be audited and compliant with requirements of 21 CFR Part 11  and has format suited to review by regulators.,CDISC glossary,,,,,,electronic case report tabulation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000083,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,electronic case report tabulation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Jennifer Fostel,,
http://purl.obolibrary.org/obo/CHEBI_23995,N-ethyl-N-nitrosourea,,A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by ethyl and nitroso groups.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by ethyl and nitroso groups.,,,,,,,N-ethyl-N-nitrosourea,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:23995,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,N-ethyl-N-nitrosourea,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001025,binding constant determination assay,,A binding assay where the specified output is a binding constant,false,,,http://purl.obolibrary.org/obo/OBI_0001146,,,,,,,,,,,,,,,,,,,A binding assay where the specified output is a binding constant,,,,,,,binding constant determination assay,,Determination of KD value for an antibody binding a protein using a BIACORE assay. ,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001025,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,binding constant determination assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Bjoern Peters, Randi Vita, Jason Greenbaum",,
http://purl.obolibrary.org/obo/OBI_0000893,real time polymerase chain reaction assay,kinetic polymerase chain reaction|quantitative real time polymerase chain reaction|qPCR|Q-PCR|real time PCR,"A laboratory technique based on the PCR, which is used to
amplify and simultaneously quantify a specific DNA
molecule based on the use of complementary probes/primers. It enables
both detection and quantification (as absolute number of copies or relative
amount when normalized to DNA input or additional normalizing genes) of one
or more specific sequences in a DNA sample.",false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,kinetic polymerase chain reaction|quantitative real time polymerase chain reaction|qPCR|Q-PCR,,,,,,,,,,,,,,,"A laboratory technique based on the PCR, which is used to
amplify and simultaneously quantify a specific DNA
molecule based on the use of complementary probes/primers. It enables
both detection and quantification (as absolute number of copies or relative
amount when normalized to DNA input or additional normalizing genes) of one
or more specific sequences in a DNA sample.",WEB: http://en.wikipedia.org/wiki/Real-time_polymerase_chain_reaction,,,,,,real time polymerase chain reaction assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000415,,,,,,,,,,,,,,,,OBI:0000893,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,real time PCR,real time polymerase chain reaction assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person: Bjoern Peters|person: Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0001041,stabilization function,isolation function,A stabilization function is a function that holds or isolates an entity such as an instrument or specimen steadfast or at an unfluctuating level or quantity.,false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,isolation function,,,,,,,,,,,,,,,A stabilization function is a function that holds or isolates an entity such as an instrument or specimen steadfast or at an unfluctuating level or quantity.,,,,,,,stabilization function,,"",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001041,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,stabilization function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,EAGLE-I,,
http://purl.obolibrary.org/obo/OBI_0000825,to be treated with placebo role,,"A study subject role which begins to exist when a subject is assigned to be one of those who will receive a placebo, and realized in a study execution in which they receive the placebo",false,,,http://purl.obolibrary.org/obo/OBI_0000097,,,,,,,,,,,,,,,,,2009/09/28 Alan Ruttenberg. Fucoidan-use-case,,"A study subject role which begins to exist when a subject is assigned to be one of those who will receive a placebo, and realized in a study execution in which they receive the placebo",,,,,,,to be treated with placebo role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000825,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,to be treated with placebo role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0000521,flame ionization detector,FID,A flame ionization detector is a GC detector that consist of a hydrogen/air flame and a collector plate which are normally heated independently of the chromatographic oven. Heating is necessary in order to prevent condensation of water generated by the flame and also to prevent any hold-up of solutes as they pass from the column to the flame. There is an electrode above the flame to collect the ions formed at a hydrogen/air flame. The number of ions hitting the collector is measured and a signal is generated. Flame ionization detectors are most widely used and generally applicable for gas chromatography and hence is used for routine and general purpose analysis. It is easy to use but destructive of the sample.,false,,,http://purl.obolibrary.org/obo/OBI_0000637,,,,FID,,,,,,,,,,,,,,,A flame ionization detector is a GC detector that consist of a hydrogen/air flame and a collector plate which are normally heated independently of the chromatographic oven. Heating is necessary in order to prevent condensation of water generated by the flame and also to prevent any hold-up of solutes as they pass from the column to the flame. There is an electrode above the flame to collect the ions formed at a hydrogen/air flame. The number of ions hitting the collector is measured and a signal is generated. Flame ionization detectors are most widely used and generally applicable for gas chromatography and hence is used for routine and general purpose analysis. It is easy to use but destructive of the sample.,WEB:<http://homepages.onsnet.nu/%7Ealkema/html/whatisgc.html>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01197,,,,,,flame ionization detector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000521,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,flame ionization detector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000542,gas chromatography equipment,,Any device used in a gas chromatography experiment.,false,,,http://purl.obolibrary.org/obo/OBI_0000048,,,,,,,,,,,,,,,,,will become defined class/xps,,Any device used in a gas chromatography experiment.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01030,,,,,,gas chromatography equipment,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000542,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,gas chromatography equipment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000051,liquid chromatography mass spectrometry platform,,"A liquid chromatography mass spectrometry platform is a platform that is the collection of instrument, software and reagents needed to perform a liquid chromatography mass spectrometry protocol. definition_source: OBI.",false,,,http://purl.obolibrary.org/obo/OBI_0000832|http://purl.obolibrary.org/obo/OBI_0000932,,,,,,,,,,,,,,,,,,,"A liquid chromatography mass spectrometry platform is a platform that is the collection of instrument, software and reagents needed to perform a liquid chromatography mass spectrometry protocol. definition_source: OBI.",OBI Instrument branch,,,,,,liquid chromatography mass spectrometry platform,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000453|http://purl.obolibrary.org/obo/OBI_0000372,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000049|http://purl.obolibrary.org/obo/OBI_0000048,,,,,,,,,,,,,,,,OBI:0000051,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,liquid chromatography mass spectrometry platform,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI instrument branch,,
http://purl.obolibrary.org/obo/OBI_0001506,specimen with pre- or post-mortem status,,A specimen that has been established to be taken from a live (pre-mortem) or dead (post-mortem) organism.,false,,,http://purl.obolibrary.org/obo/OBI_0100051,,,,,,,,,,,,,,,,,,,A specimen that has been established to be taken from a live (pre-mortem) or dead (post-mortem) organism.,MO_84 OrganismStatus,,,,,"organizational term, used in description of specimen that is created from known pre- or post-mortem status",specimen with pre- or post-mortem status,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001506,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,specimen with pre- or post-mortem status,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/NCBITaxon_10116,Rattus norvegicus,rat|Norway rat|rats|Rattus sp. strain Wistar|brown rat,,false,,,http://purl.obolibrary.org/obo/NCBITaxon_39107,,,,rat|Norway rat|rats|Rattus sp. strain Wistar|brown rat,,,,,,,,,,,,,,,,,,,,,,Rattus norvegicus,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:10116,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Rattus norvegicus,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0042110,T cell activation,,"The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.",false,,,http://purl.obolibrary.org/obo/GO_0008150,,,,,,,,,,,,,,,,,,,"The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.",,,,,,,T cell activation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0042110,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,T cell activation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000032,clinical research coordinator role,clinical research coordinator,a worker role comprised of handling the administrative duties of a trial or study.,false,,,http://purl.obolibrary.org/obo/OBI_0000116,,,,clinical research coordinator,,,,,,,,,,,,,,,a worker role comprised of handling the administrative duties of a trial or study.,,,,,,,clinical research coordinator role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000032,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,clinical research coordinator role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0001997,hydrogen/deuterium exchange assay measuring binding of a B cell epitope:antibody complex,qualitative binding|hydrogen/deuterium exchange,A B cell epitope qualitative binding to antibody assay that uses a hydrogen/deuterium exchange assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001703,,,,,,,,,,,,,,,,,,,A B cell epitope qualitative binding to antibody assay that uses a hydrogen/deuterium exchange assay.,IEDB,,,,,,hydrogen/deuterium exchange assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001997,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|hydrogen/deuterium exchange,,,,,,,,,,,,,,,,,,,,,,hydrogen/deuterium exchange assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0600049,DNA polymerase amplification,,DNA polymerase amplification is an enzymatic amplification which uses DNA polymerase enzyme to make copies of a DNA contained in biomaterial used as input,false,,,http://purl.obolibrary.org/obo/OBI_0600058,,,,,,,,,,,,,,,,,,,DNA polymerase amplification is an enzymatic amplification which uses DNA polymerase enzyme to make copies of a DNA contained in biomaterial used as input,OBI branch derived,,,,,,DNA polymerase amplification,,The use of taq polymerase to amplify a DNA fragment during a PCR.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/GO_0042575,,,,OBI:0600049,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,DNA polymerase amplification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Kevin Clancy|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001330,ELISA measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells,CXCL9/MIG release|ELISA,An assay of epitope specific chemokine (C-X-C motif) ligand 9 production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001459,,,,,,,,,,,,,,,,,,,An assay of epitope specific chemokine (C-X-C motif) ligand 9 production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001330,,,,,,,,,,,,,,,,,,,,,,,,CXCL9/MIG release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0500013,hyper graeco latin square design,,PRS to do,false,,,http://purl.obolibrary.org/obo/OBI_0500007,,,,,,,,,,,,,,,,,no example found in pubmed->not in use in the community,,PRS to do,Adapted from: http://www.itl.nist.gov/div898/handbook/pri/section3/pri3321.htm and,,,,,,hyper graeco latin square design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500013,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,hyper graeco latin square design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_1110091,immune epitope carrier role,,A role inhering in a material entity that is covalently bound to an epitope in order to increase the epitopes immunogenicity.,false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,,,,,,,,,,,,,,,,A role inhering in a material entity that is covalently bound to an epitope in order to increase the epitopes immunogenicity.,IEDB,,,,,"03/21/2010,  BP: surveying the literature, this seems to be a messy term. Need to clarify what material entities can be carriers, and if only immunogenicity (not antigenicity) is effected by their presence.",immune epitope carrier role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110091,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,immune epitope carrier role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001474,lowess group transformation,,"A lowess transformation where a potentially different normalization curve is generated and used for two or more groups (delineated by some criteria); criteria could include blocks (e.g. print-tip groups) on an array, or the day on which mass spectrometry was performed. ",false,,,http://purl.obolibrary.org/obo/OBI_0001477,,,,,,,,,,,,,,,,,,,"A lowess transformation where a potentially different normalization curve is generated and used for two or more groups (delineated by some criteria); criteria could include blocks (e.g. print-tip groups) on an array, or the day on which mass spectrometry was performed. ",MO_861 lowess_group_normalization,,,,,,lowess group transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001474,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,lowess group transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0001579,cell lysate MHC binding assay measuring binding of a MHC:ligand complex,qualitative binding|lysate MHC,A MHC binding qualitative binding to ligand assay using MHC in a cell lysate.,false,,,http://purl.obolibrary.org/obo/OBI_0002072,,,,,,,,,,,,,,,,,,,A MHC binding qualitative binding to ligand assay using MHC in a cell lysate.,IEDB,,,,,,cell lysate MHC binding assay measuring binding of a MHC:ligand complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001579,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|lysate MHC,,,,,,,,,,,,,,,,,,,,,,cell lysate MHC binding assay measuring binding of a MHC:ligand complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001373,epitope specific interleukin-8 production by T cells,,A process of interleukin-8 production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/OBI_0001193|http://purl.obolibrary.org/obo/GO_0032637,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of interleukin-8 production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific interleukin-8 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001373,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific interleukin-8 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OGMS_0000015,clinical history,,A series of statements representing health-relevant qualities of a patient and of a patient's family.,false,,,http://purl.obolibrary.org/obo/IAO_0000030,,,,,,,,,,,,,,,,,,,A series of statements representing health-relevant qualities of a patient and of a patient's family.,,,,,,,clinical history,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OGMS:0000015,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ogms.owl,,,,,,,,,,,,,,,,,,,clinical history,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200138,subgraph degree calculation,,A network subgraph quality calculation in which an input data set describing subgraphs and relationship edges between subgraphs and other network objects is used to enumerate the number of unique relationships of an individual subgraph.,false,,,http://purl.obolibrary.org/obo/OBI_0200137,,,,,,,,,,,,,,,,,,,A network subgraph quality calculation in which an input data set describing subgraphs and relationship edges between subgraphs and other network objects is used to enumerate the number of unique relationships of an individual subgraph.,PERSON: Richard Scheuermann,,,,,,subgraph degree calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200138,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,subgraph degree calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Richard Scheuermann,,
http://purl.obolibrary.org/obo/OBI_0000640,indirect detection probe,,An NMR probe designed to allow the indirect detection of acquisition nuclei.,false,,,http://purl.obolibrary.org/obo/OBI_0000516,,,,,,,,,,,,,,,,,NMR device,,An NMR probe designed to allow the indirect detection of acquisition nuclei.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400281,,,,,,indirect detection probe,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000640,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,indirect detection probe,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/NCBITaxon_2,Bacteria,eubacteria,,false,,,http://purl.obolibrary.org/obo/OBI_0100026,,,,eubacteria,,,,,,,,,,,,,,,,,,,,,,Bacteria,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,NCBITaxon:2,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/ncbitaxon.owl,,,,,,,,,,,,,,,,,,,Bacteria,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0600067,specific labeling,,a labeling in which the labeling reagent used  has a specificity to bind only certain components of the input material,false,,,http://purl.obolibrary.org/obo/OBI_0600038,,,,,,,,,,,,,,,,,"definition blessed by Allyson, Bjoern, Jay & Randi",,a labeling in which the labeling reagent used  has a specificity to bind only certain components of the input material,OBI branch derived,,,,,,specific labeling,,The addition of anti-CD8 antibody for an ICCS assay in order to selectively stain the CD8+ cells,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600067,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,specific labeling,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0002002,Illumina HiSeq 2500,HiSeq 2500,"A DNA sequencer which is manufactured by the Illumina corporation, with two flow cells and a throughput of up to 160 Gb per day. Built upon sequencing by synthesis technology, the machine is optimized for generation of data for batching multiple samples or rapid results on a few samples.",false,,,http://purl.obolibrary.org/obo/OBI_0400103,,,,HiSeq 2500,,,,,,,,,,,,,,,"A DNA sequencer which is manufactured by the Illumina corporation, with two flow cells and a throughput of up to 160 Gb per day. Built upon sequencing by synthesis technology, the machine is optimized for generation of data for batching multiple samples or rapid results on a few samples.",http://res.illumina.com/documents/products/datasheets/datasheet_hiseq2500.pdf,,,,,,Illumina HiSeq 2500,,"Spaethling, Jennifer M., and James H. Eberwine. ""Single-cell transcriptomics for drug target discovery."" Current opinion in pharmacology (2013). pmid:23725882",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002002,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Illumina HiSeq 2500,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"PERSON: Venkat Malladi, Chris Stoeckert, Jie Zheng, Alan Ruttenberg",,
http://purl.obolibrary.org/obo/OBI_0001188,epitope disease exacerbation experiment,exacerbation assay,an epitope intervention experiment that tests the ability of inducing an epitope immune response to increase the severity of an existing disease in the host.,false,,,http://purl.obolibrary.org/obo/OBI_0001178,,,,,,,,,,,,,,,,,,,an epitope intervention experiment that tests the ability of inducing an epitope immune response to increase the severity of an existing disease in the host.,,,,,,,epitope disease exacerbation experiment,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001188,,,,,,,,,,,,,,,,,,,,,,,,exacerbation assay,,,,,,,,,,,,,,,,,,,,,,epitope disease exacerbation experiment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0200198,tandem mass spectrometry,,Tandem mass spectrometry is a data transformation that uses two or more analyzers separated by a region in which ions can be induced to fragment by transfer of energy (frequently by collision with other molecules).,false,,,http://purl.obolibrary.org/obo/OBI_0200085,,http://purl.obolibrary.org/obo/OBI_0200197,,,,,,,,,,,,,,,,,Tandem mass spectrometry is a data transformation that uses two or more analyzers separated by a region in which ions can be induced to fragment by transfer of energy (frequently by collision with other molecules).,PERSON: Tina Boussard,,,,,,tandem mass spectrometry,,"A precursor ion is selected in the first stage, allowed to fragment and then all resultant masses are scanned in the second mass analyzer and detected in the detector that is positioned after the second mass analyzer. This experiment is commonly performed to identify transitions used for quantification by tandem MS.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200198,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,tandem mass spectrometry,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Tina Boussard|PERSON: James Malone,,
http://purl.obolibrary.org/obo/OBI_0001146,binding assay,,An assay with the objective to characterize the disposition of two or more material entities to form a complex.,false,,,http://purl.obolibrary.org/obo/OBI_0000070,,,,,,,,,,,,,,,,,,,An assay with the objective to characterize the disposition of two or more material entities to form a complex.,"PERSON:Bjoern Peters, Randi Vita, Jason Greenbaum",,,,,,binding assay,,"Determination of KD value for an antibody binding a protein using a BIACORE assay. Using plate bound antigen in an ELISA to determine if a mixture of serum antibodies bind the antigen.nnThe following are NOT binding assays, as the desired output is not binding data: RNA microarray experiments to determine levels of gene expression. ChIP experiments to determine where in DNA a transcription factor binds. Using an IL-2 antibody on an ELISA plate to determine presence of IL-2 after stimulating a T cell culture. ",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001146,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,binding assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Bjoern Peters, Randi Vita, Jason Greenbaum",,
http://purl.obolibrary.org/obo/OBI_0001685,amplification of intermethylated sites (AIMS) assay ,"AIMS assay,intermethylated site amplification ", amplification of intermethylated sites (AIMS) is an assay appropriate for genome-wide estimates of DNA methylation and the discovery of specific methylated sequences. AIMS is based on the differential enzymatic digestion of genomic DNA with methylation-sensitive and methylation-insensitive isoschizomers followed by restrained PCR amplification of methylated sequences.,false,,,http://purl.obolibrary.org/obo/OBI_0000634|http://purl.obolibrary.org/obo/OBI_0000070,,,,"AIMS assay,intermethylated site amplification ",,,,,,,,,,,,,,, amplification of intermethylated sites (AIMS) is an assay appropriate for genome-wide estimates of DNA methylation and the discovery of specific methylated sequences. AIMS is based on the differential enzymatic digestion of genomic DNA with methylation-sensitive and methylation-insensitive isoschizomers followed by restrained PCR amplification of methylated sequences.,PMID: 18987810,,,,,,amplification of intermethylated sites (AIMS) assay ,,Analysis of DNA methylation by amplification of intermethylated sites (AIMS).PMID:18987810,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001685,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,amplification of intermethylated sites (AIMS) assay ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Philippe Rocca-Serra; Marcus Chibucos,,
http://purl.obolibrary.org/obo/CHEBI_53526,tritiated thymidine,,Thymidine linked to the radioisotope tritium. Used to label DNA in the study of cellular and viral DNA synthesis.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,Thymidine linked to the radioisotope tritium. Used to label DNA in the study of cellular and viral DNA synthesis.,,,,,,,tritiated thymidine,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:53526,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,tritiated thymidine,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001207,epitope specific macrophage inflammatory protein-1 alpha production by T cells,,A process of macrophage inflammatory protein-1 alpha production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0071608|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of macrophage inflammatory protein-1 alpha production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific macrophage inflammatory protein-1 alpha production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001207,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific macrophage inflammatory protein-1 alpha production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/IAO_0000012,obsolete2_digital entity,,A digital entity is an information entity which is a collection of bits that can be interpreted by a computer. Two digital entities are the same if they are bitwise identical.,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,A digital entity is an information entity which is a collection of bits that can be interpreted by a computer. Two digital entities are the same if they are bitwise identical.,group:OBI|OBI_0000261,,,,,"3/22/2009 Alan Ruttenberg, obsoleted per http://groups.google.com/group/information-ontology/browse_thread/thread/789ad4b7708d5cf4

Superclass was 'digitial quality'",obsolete2_digital entity,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000103,,,,,,,,,,,,,,,,,,IAO:0000012,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete2_digital entity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,person:Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0400047,gas laser,,A gas laser is a laser in which the lasing medium is a gas. The laser medium is places between two parallel mirrors for light emission amplification. The gas is excited to emit light via an external light source or an electric current discharging through the gas.,false,,,http://purl.obolibrary.org/obo/OBI_0400064,,,,,,,,,,,,,,,,,,,A gas laser is a laser in which the lasing medium is a gas. The laser medium is places between two parallel mirrors for light emission amplification. The gas is excited to emit light via an external light source or an electric current discharging through the gas.,John Quinn|http://en.wikipedia.org/wiki/Gas_laser,,,,,,gas laser,,helium-neon gas laser used to erradiate cells in a flow cytometer.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400047,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,gas laser,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000084,polystyrene tube,,a polystyrene tube is a test tube made of polystyrene,false,,,http://purl.obolibrary.org/obo/OBI_0000836,,,,,,,,,,,,,,,,,,,a polystyrene tube is a test tube made of polystyrene,PERSON: Chris Stoeckert,,,,,,polystyrene tube,,Polystyrene tubes can be used  to contain tissue culture cells during centrifgation,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000084,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,polystyrene tube,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0001546,comparative phenotypic assessment,,Interpreting data from assays that evaluate the qualities or dispositions inhering in an organism or organism part and comparing it to data from other organisms to make a conclusion about a phenotypic difference,false,,,http://purl.obolibrary.org/obo/OBI_0000338|http://purl.obolibrary.org/obo/OBI_0001834,,,,,,,,,,,,,,,,,6/1/2012: We will utilize 'comparative qualities' once they are available in BFO2,,Interpreting data from assays that evaluate the qualities or dispositions inhering in an organism or organism part and comparing it to data from other organisms to make a conclusion about a phenotypic difference,Philly workshop 2011,,,,,,comparative phenotypic assessment,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001546,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,comparative phenotypic assessment,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philly workshop 2011,,
http://purl.obolibrary.org/obo/OBI_0001738,X-ray crystallography assay determining the 3D structure of a B cell epitope:antibody complex,3D structure|x-ray crystallography|angstroms,A B cell epitope 3D structure determination assay that uses an X-ray crystallography assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001721,,,,,,,,,,,,,,,,,,,A B cell epitope 3D structure determination assay that uses an X-ray crystallography assay.,IEDB,,,,,,X-ray crystallography assay determining the 3D structure of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001738,,,,,,,,,,,,,,,,,,,,,,,,3D structure|x-ray crystallography|angstroms,,,,,,,,,,,,,,,,,,,,,,X-ray crystallography assay determining the 3D structure of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000202,investigation agent role,investigator|study person role,"A role borne by an entity and that is realized in a process that is part of an investigation in which an objective is achieved. These processes include, among others: planning, overseeing, funding, reviewing.|Philly2013: Historically, this role would have been borne only by humans or organizations. However, we now also want to enable investigations run by robot scientists such as ADAM (King et al, Science, 2009)",false,,,http://purl.obolibrary.org/obo/BFO_0000023,,,,investigator,,,,,,,,,,,,,"Feb 10, 2009.  changes after discussion at OBI Consortium Workshop Feb 2-6, 2009.  accepted as core term.",,"A role borne by an entity and that is realized in a process that is part of an investigation in which an objective is achieved. These processes include, among others: planning, overseeing, funding, reviewing.",OBI,,,,,"Philly2013: Historically, this role would have been borne only by humans or organizations. However, we now also want to enable representing investigations run by robot scientists such as ADAM (King et al, Science, 2009)|Implementing a study means carrying out or performing the study and providing reagents or other materials used in the study and other tasks without which the study would not happen.",investigation agent role,,"The person perform microarray experiments and submit microarray results (including raw data, processed data) with experiment description to ArrayExpress.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000202,,,,,,,,,,,,,,,,,,"Philly2013: Historically, this role would have been borne only by humans or organizations. However, we now also want to enable investigations run by robot scientists such as ADAM (King et al, Science, 2009)",,,,,,,,,,,,,,,,,,,,,,,,,,,study person role,investigation agent role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GROUP:  Role Branch,,
http://purl.obolibrary.org/obo/OBI_0001511,disposition to be a product of antigen processing and presentation,,A disposition of a material entity to be presented by MHC molecules on the cell surface as a result of antigen processing by an antigen presenting cell. ,false,,,http://purl.obolibrary.org/obo/BFO_0000016,,,,,,,,,,,,,,,,,,,A disposition of a material entity to be presented by MHC molecules on the cell surface as a result of antigen processing by an antigen presenting cell. ,IEDB,,,,,,disposition to be a product of antigen processing and presentation,,The disposition of the peptide AALKNLPLI to be created from the source protein long-chain-fatty-acid--CoA ligase 3 in murine macrophages through cleavage before residue 599 and after residue 607 by the proteasome and subsequent transport into the ER.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001511,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,disposition to be a product of antigen processing and presentation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001573,DNA sequence data,,A sequence data item that is about the primary structure of DNA,false,,,http://purl.obolibrary.org/obo/OBI_0000973,,,,,,,,,,,,,,,,,"8/29/11 call: This is added after a request from Melanie and Yu. They should review it further. This should be a child of 'sequence data', and as of the current definition will infer there.  ",,A sequence data item that is about the primary structure of DNA,OBI call; Melanie Courtout,,,,,,DNA sequence data,,The part of a FASTA file that contains the letters ACTGGGAA ,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001573,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000811,,,,,,,,,,,,,,,,DNA sequence data,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI call; Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000520,clinical chemistry assay,detection of analyte in blood sample|chemical pathology|clinical chemistry,a process which uses analytical methods to produce measurements and data on the concentration of a chemical parameters (analytes) present in a bodily fluid collected from an organism.,false,,,http://purl.obolibrary.org/obo/OBI_0000443,,http://purl.obolibrary.org/obo/OBI_0000437,,detection of analyte in blood sample|chemical pathology,,,,,,,,,,,,,,,a process which uses analytical methods to produce measurements and data on the concentration of a chemical parameters (analytes) present in a bodily fluid collected from an organism.,adapted from Wikipedia,,,,,"3/26/09: There needs to be a restriction set that specifies which type of evaluants are used in the assay, somewhere along the lines of 'sample derived of bodily fluid'",clinical chemistry assay,,"Influence of hydroxyethyl starch (6% HES 130/0.4) administration on hematology and clinical chemistry parameters.
Mueller T, Schimetta W, Dieplinger B, Loeffler P, Rehm M, Kreimeier U, Poelz W, Haltmayer M.
Clin Chem Lab Med. 2008;46(4):558-62.
PMID: 18605936",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000520,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,clinical chemistry,clinical chemistry assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/CHEBI_9754,tris,,A primary amino compound that is tert-butylamine in which one hydrogen attached to each methyl group is replaced by a hydroxy group. A compound widely used as a biological buffer substance in the pH range 7--9; pKa = 8.3 at 20 degreeC; pKa = 7.82 at 37 degreeC.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,A primary amino compound that is tert-butylamine in which one hydrogen attached to each methyl group is replaced by a hydroxy group. A compound widely used as a biological buffer substance in the pH range 7--9; pKa = 8.3 at 20 degreeC; pKa = 7.82 at 37 degreeC.,,,,,,,tris,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:9754,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,tris,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001106,pulsed-field gel electrophoresis system,,A gel electrophoresis system that is used to separate very large molecules of DNA.,false,,,http://purl.obolibrary.org/obo/OBI_0001121,,,,,,,,,,,,,,,,,,,A gel electrophoresis system that is used to separate very large molecules of DNA.,http://en.wikipedia.org/wiki/Pulsed_field_gel_electrophoresis,,,,,,pulsed-field gel electrophoresis system,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001106,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,pulsed-field gel electrophoresis system,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0000626,DNA sequencing,nucleotide sequencing,DNA sequencing is a sequencing process which uses deoxyribonucleic acid as input and results in a the creation of DNA sequence information artifact using a DNA sequencer instrument.,false,,,http://purl.obolibrary.org/obo/OBI_0600047,,http://purl.obolibrary.org/obo/OBI_0000441,,,,,,,,,,,,,,,,,DNA sequencing is a sequencing process which uses deoxyribonucleic acid as input and results in a the creation of DNA sequence information artifact using a DNA sequencer instrument.,OBI Branch derived,,,,,,DNA sequencing,,"Genomic deletions of OFD1 account for 23% of oral-facial-digital type 1 syndrome after negative DNA sequencing. Thauvin-Robinet C, Franco B, Saugier-Veber P, Aral B, Gigot N, Donzel A, Van Maldergem L, Bieth E, Layet V, Mathieu M, Teebi A, Lespinasse J, Callier P, Mugneret F, Masurel-Paulet A, Gautier E, Huet F, Teyssier JR, Tosi M, Frébourg T, Faivre L.  Hum Mutat. 2008 Nov 19. PMID: 19023858",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0400103,,,,,,,,,,,,,,,OBI:0000626,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,nucleotide sequencing,DNA sequencing,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/IAO_0000128,obsolete_identifier,,,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,,,,,,,"_identifier is a container under information content entity for collecting types of terms to indicate a specific instance or clas of what was used or participated in an investigation. Identifiers are borne by a product or its packaging, and can be encoded in a variety of other information objects, such as bar codes, numerals, or patterns of dots.

Note: everybody agreed that identifier is probably a too general term. We however felt that it would be appropriate to group ""identifiying"" terms under some kind of umbrella. We therefore propose to use _identifier for that purpose. As per OBI conventions, the _ prefixing identifier indicates that this is a helper class and shouldn't be considered as final.",obsolete_identifier,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000121,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000226,,,,,,,,,,,,,,,,,,IAO:0000128,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_identifier,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001028,feature extraction,,A planed process with objective of obtaining quantified values from an image.|,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,http://purl.obolibrary.org/obo/OBI_0200005,,,,,,,,,,,,,,,,,A planed process with objective of obtaining quantified values from an image.,MO_928: feature_extraction,,,,,,feature extraction,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000101,http://purl.obolibrary.org/obo/IAO_0000027,,,OBI:0001028,,,,,,,,,,,,,,,,,,"",,,,,,,,,,,,,,,,,,,,,,,,,,,,feature extraction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Jie Zheng,,
http://purl.obolibrary.org/obo/OBI_0200139,quantitative subgraph degree calculation,,A network subgraph quality calculation in which an input data set describing subgraphs and quantitative relationship edges between subgraphs and other network objects is used to sum the quantitative relationships of an individual subgraph.,false,,,http://purl.obolibrary.org/obo/OBI_0200137,,,,,,,,,,,,,,,,,,,A network subgraph quality calculation in which an input data set describing subgraphs and quantitative relationship edges between subgraphs and other network objects is used to sum the quantitative relationships of an individual subgraph.,PERSON: Richard Scheuermann,,,,,,quantitative subgraph degree calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200139,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,quantitative subgraph degree calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Richard Scheuermann,,
http://purl.obolibrary.org/obo/OBI_0100017,blood serum specimen,,A material entity which derives from blood and corresponds to blood plasma without fibrinogen or the other clotting factors.,false,,,http://purl.obolibrary.org/obo/OBI_0000953,,,,,,,,,,,,,,,,,,,A material entity which derives from blood and corresponds to blood plasma without fibrinogen or the other clotting factors.,WEB: http://en.wikipedia.org/wiki/Blood_plasma,,,,,,blood serum specimen,,PMID: 18229666.Adv Med Sci. 2007;52 Suppl 1:204-6.Antioxidant activity of blood serum and saliva in patients with periodontal disease treated due to epilepsy.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000112,,,,,,,,,,,,OBI:0100017,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,blood serum specimen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot|PERSON: Maura Gasparetto|PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000079,culture medium,,a processed material that provides the needed nourishment for microorganisms or cells grown in vitro.,false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,,,,,,,,,,,,,,,,a processed material that provides the needed nourishment for microorganisms or cells grown in vitro.,OBI,,,,,"changed from a role to a processed material based on on Aug 22, 2011 dev call. Details see the tracker item: http://sourceforge.net/tracker/?func=detail&aid=3325270&group_id=177891&atid=886178
Modification made by JZ.",culture medium,,"A growth medium or culture medium is a substance in which microorganisms or cells can grow.  Wikipedia, growth medium, Feb 29, 2008",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000079,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,culture medium,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Jennifer Fostel, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0200150,MA transformation,,"An MA transformation is a data transformation which takes as input a collection of data points (g_1, r_1), (g_2, r_2), ..., (g_n, r_n)  with the r_i and g_i positive real numbers, and whose output is the collection of data points (A_1, M_1), (A_2, M_2), ..., (A_n, M_n) where, for each i, A_i=(log(g_i)+log(r_i))/2 and M_i=log(r_i)-log(g_i). Here log denotes a logarithmic transformation.",false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,"An MA transformation is a data transformation which takes as input a collection of data points (g_1, r_1), (g_2, r_2), ..., (g_n, r_n)  with the r_i and g_i positive real numbers, and whose output is the collection of data points (A_1, M_1), (A_2, M_2), ..., (A_n, M_n) where, for each i, A_i=(log(g_i)+log(r_i))/2 and M_i=log(r_i)-log(g_i). Here log denotes a logarithmic transformation.",PERSON: Elisabetta Manduchi,,,,,,MA transformation,,"MA transformations are typically used in microarray data analyses. In this context, the g_i and r_i represent the reporter intensities in the two channels of a 2-channel assay or the reporter intensities in two related one-channel assays. Typically the base used for the logarithm is 2.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200150,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,MA transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0002022,Illumina HiSeq 1000,HiSeq 1000,"A DNA sequencer which is manufactured by the Illumina corporation, with a single flow cell and a throughput of up to 35 Gb per day. It supports sequencing of single, long or short insert paired end clone libraries relying on sequencing by synthesis technology.",false,,,http://purl.obolibrary.org/obo/OBI_0400103,,,,HiSeq 1000,,,,,,,,,,,,,,,"A DNA sequencer which is manufactured by the Illumina corporation, with a single flow cell and a throughput of up to 35 Gb per day. It supports sequencing of single, long or short insert paired end clone libraries relying on sequencing by synthesis technology.",http://res.illumina.com/documents/products/datasheets/datasheet_hiseq_systems.pdf,,,,,,Illumina HiSeq 1000,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002022,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Illumina HiSeq 1000,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0001649,RIA measuring binding of a B cell epitope:antibody complex,qualitative binding|radio immuno assay (RIA),A B cell epitope qualitative binding to antibody assay that uses a radio immuno assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001703|http://purl.obolibrary.org/obo/OBI_0001491,,,,,,,,,,,,,,,,,,,A B cell epitope qualitative binding to antibody assay that uses a radio immuno assay.,IEDB,,,,,,RIA measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001649,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|radio immuno assay (RIA),,,,,,,,,,,,,,,,,,,,,,RIA measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/UBERON_0000955,brain,,"The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP].",false,,,http://purl.obolibrary.org/obo/CARO_0001008,,,,,,,,,,,,,,,,,,,"The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP].",,,,,,,brain,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UBERON:0000955,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uberon.owl,,,,,,,,,,,,,,,,,,,brain,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200130,node degree calculation,,A node quality calculation in which an input data set describing object nodes and relationship edges between object nodes is used to enumerate the number of unique relationships of an individual object node.,false,,,http://purl.obolibrary.org/obo/OBI_0200129,,,,,,,,,,,,,,,,,,,A node quality calculation in which an input data set describing object nodes and relationship edges between object nodes is used to enumerate the number of unique relationships of an individual object node.,PERSON: Richard Scheuermann,,,,,,node degree calculation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200130,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,node degree calculation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Richard Scheuermann,,
http://purl.obolibrary.org/obo/OBI_0001568,purified MHC competitive binding assay measuring half maximal inhibitory concentration [IC50] of a MHC:ligand complex using radioactivity detection,half maximal inhibitory concentration (IC50)|purified MHC/competitive/radioactivity|nM,A purified MHC ligand binding half maximal inhibitory concentration (IC50) determination assay that uses radioactivity detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation.,false,,,http://purl.obolibrary.org/obo/OBI_0001491|http://purl.obolibrary.org/obo/OBI_0001992,,,,,,,,,,,,,,,,,,,A purified MHC ligand binding half maximal inhibitory concentration (IC50) determination assay that uses radioactivity detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation.,IEDB,,,,,,purified MHC competitive binding assay measuring half maximal inhibitory concentration [IC50] of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001568,,,,,,,,,,,,,,,,,,,,,,,,half maximal inhibitory concentration (IC50)|purified MHC/competitive/radioactivity|nM,,,,,,,,,,,,,,,,,,,,,,purified MHC competitive binding assay measuring half maximal inhibitory concentration [IC50] of a MHC:ligand complex using radioactivity detection,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000391,energy supply function,,An energy supply function is a function to supply or transfer energy from an energy source to a consumer of the energy,false,,,http://purl.obolibrary.org/obo/BFO_0000034,,,,,,,,,,,,,,,,,,,An energy supply function is a function to supply or transfer energy from an energy source to a consumer of the energy,,,,,,,energy supply function,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000391,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,energy supply function,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Frank Gibson,,
http://purl.obolibrary.org/obo/OBI_0002000,Genome Analyzer IIx,Illumina Genome Analyzer IIx|Illumina GA IIx,"An Illumina Genome Analyzer II which is manufactured by the Illumina corporation. It supports sequencing of single, long or short insert paired end clone libraries relying on sequencing by synthesis technology. The Genome Analyzer IIx is the most widely adopted next-generation sequencing platform and proven and published across the broadest range of research applications.",false,,,http://purl.obolibrary.org/obo/OBI_0000703,,,,Illumina Genome Analyzer IIx|Illumina GA IIx,,,,,,,,,,,,,,,"An Illumina Genome Analyzer II which is manufactured by the Illumina corporation. It supports sequencing of single, long or short insert paired end clone libraries relying on sequencing by synthesis technology. The Genome Analyzer IIx is the most widely adopted next-generation sequencing platform and proven and published across the broadest range of research applications.",ENCODE group,,,,,,Genome Analyzer IIx,,"Gravina, Michael T., Jenny H. Lin, and Stuart S. Levine. ""Lane-by-lane sequencing using Illumina's Genome Analyzer II."" BioTechniques 54.5 (2013): 265-269. PMID: 23662897
",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002000,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Genome Analyzer IIx,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"PERSON: Venkat Malladi, Chris Stoeckert, Jie Zheng, Alan Ruttenberg",,
http://purl.obolibrary.org/obo/OBI_0000861,Likelihood-ratio test,,Likelihood-ratio is a data transformation which tests whether there is evidence of the need to move from a simple model to a more complicated one (where the simple model is nested within the complicated one); tests of the goodness-of-fit between two models.,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,Likelihood-ratio is a data transformation which tests whether there is evidence of the need to move from a simple model to a more complicated one (where the simple model is nested within the complicated one); tests of the goodness-of-fit between two models.,,,,,,,Likelihood-ratio test,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000861,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Likelihood-ratio test,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Tina Boussard,,
http://purl.obolibrary.org/obo/OBI_0000052,microarray platform,,"A microarray platform is a platform that contains the instruments, software and reagents needed to perform a microarray protocol. definition_source: OBI.",false,,,http://purl.obolibrary.org/obo/OBI_0001034,,,,,,,,,,,,,,,,,,,"A microarray platform is a platform that contains the instruments, software and reagents needed to perform a microarray protocol. definition_source: OBI.",OBI Instrument branch,,,,,,microarray platform,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000401,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0400147,,,,,,,,,,,,,,,,OBI:0000052,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,microarray platform,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI Instrument branch,,
http://purl.obolibrary.org/obo/OBI_0200094,logarithmic transformation,,A logarithmic transformation is a data transformation consisting in the application of the logarithm function with a given base a (where a>0 and a is not equal to 1) to a (one dimensional) positive real number input. The logarithm function with base a can be defined as the inverse of the exponential function with the same base. See e.g. http://en.wikipedia.org/wiki/Logarithm.,false,,,http://purl.obolibrary.org/obo/OBI_0200169,,http://purl.obolibrary.org/obo/OBI_0200167,,,,,,,,,,,,,,,,,A logarithmic transformation is a data transformation consisting in the application of the logarithm function with a given base a (where a>0 and a is not equal to 1) to a (one dimensional) positive real number input. The logarithm function with base a can be defined as the inverse of the exponential function with the same base. See e.g. http://en.wikipedia.org/wiki/Logarithm.,WEB: http://en.wikipedia.org/wiki/Logarithm,,,,,,logarithmic transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200094,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,logarithmic transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0200086,spread calculation data transformation,,A spread calculation is a data transformation that has objective spread calculation.,false,,,http://purl.obolibrary.org/obo/OBI_0200000,,,,,,,,,,,,,,,,,,,A spread calculation is a data transformation that has objective spread calculation.,EDITOR,,,,,,spread calculation data transformation,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200086,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,spread calculation data transformation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone,,
http://purl.obolibrary.org/obo/CLO_0007605,CLO_0007605,,,false,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CLO:0007605,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200015,loess global transformation two-channel,,A loess global transformation two-channel is a loess global transformation in the special case where the input the result of an MA transformation applied to intensities from the two channels of a two-channel assay.,false,,,http://purl.obolibrary.org/obo/OBI_0200023,,,,,,,,,,,,,,,,,,,A loess global transformation two-channel is a loess global transformation in the special case where the input the result of an MA transformation applied to intensities from the two channels of a two-channel assay.,OTHER: Editor's generalization based on MGED Ontology term,,,,,,loess global transformation two-channel,,"Loess global normalization applied to data from a two-channel expression microarray assay, where the curve is obtained using all reporters. The goal is to remove intensity-dependent biases.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200015,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,loess global transformation two-channel,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0000729,cloning plasmid,,"A cloning plasmid is a plasmid that was engineered to contain a bacterial origin of replication, encodes for a selectable gene product and contains a cloning site.",false,,,http://purl.obolibrary.org/obo/OBI_0000430|http://purl.obolibrary.org/obo/OBI_0000737,,,,,,,,,,,,,,,,,,,"A cloning plasmid is a plasmid that was engineered to contain a bacterial origin of replication, encodes for a selectable gene product and contains a cloning site.",,,,,,Note: 'cloning vector role' is really a function. Should be dealt with globally,cloning plasmid,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000729,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cloning plasmid,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001708,assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex,dissociation constant KD|binding assay|nM,A B cell epitope binding constant determination assay that measures the dissociation constant KD.,false,,,http://purl.obolibrary.org/obo/OBI_0001709,,,,,,,,,,,,,,,,,,,A B cell epitope binding constant determination assay that measures the dissociation constant KD.,IEDB,,,,,,assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001708,,,,,,,,,,,,,,,,,,,,,,,,dissociation constant KD|binding assay|nM,,,,,,,,,,,,,,,,,,,,,,assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/IAO_0000003,measurement unit label,,A measurement unit label is as a label that is part of a scalar measurement datum and denotes a unit of measure.,false,,,http://purl.obolibrary.org/obo/IAO_0000009,,,,,,,,,,,,,,,,,,,A measurement unit label is as a label that is part of a scalar measurement datum and denotes a unit of measure.,,,,,,"2009-03-16: review of this term done during during the OBI workshop winter 2009 and the current definition was considered acceptable for use in OBI. If there is a need to modify this definition please notify OBI.|2009-03-16: provenance: a term measurement unit was
proposed for OBI (OBI_0000176) , edited by Chris Stoeckert and
Cristian Cocos, and subsequently moved to IAO where the objective for
which the original term was defined was satisfied with the definition
of this, different, term.",measurement unit label,,"Examples of measurement unit labels are liters, inches, weight per volume.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000003,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,measurement unit label,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot|PERSON: Alan Ruttenberg,,
http://purl.obolibrary.org/obo/OBI_0200134,node shortest path identification,,A node quality calculation in which a path describing the shortest path needed to transverse through connected nodes and edges to arrive at a specific target node in the network.,false,,,http://purl.obolibrary.org/obo/OBI_0200129,,,,,,,,,,,,,,,,,,,A node quality calculation in which a path describing the shortest path needed to transverse through connected nodes and edges to arrive at a specific target node in the network.,PERSON: Richard Scheuermann,,,,,,node shortest path identification,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200134,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,node shortest path identification,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Richard Scheuermann,,
http://purl.obolibrary.org/obo/OBI_0000785,study design controlled variable,controlled variable,"Controlled variable specification  is a part of a study design. They are the entities that could vary, but are kept constant to prevent their influence on the effect of the independent variable on the dependent.",false,,,http://purl.obolibrary.org/obo/IAO_0000033,,,,controlled variable,,,,,,,,,,,,,2009-03-16: work has been done on this term during during the OBI workshop winter 2009 and the current definition was considered acceptable for use in OBI. If there is a need to modify thisdefinition please notify OBI.,,"Controlled variable specification  is a part of a study design. They are the entities that could vary, but are kept constant to prevent their influence on the effect of the independent variable on the dependent.",WEB: http://en.wikipedia.org/wiki/Control_variable,,,,,"In the Philly 2013 workshop the label was chosen to distinguish it from ""controlled variable"" as used in statistical modelling|2/2/2009 Original definition: Controlled variables are also important to identify in experiments. They are the variables that are kept constant to prevent their influence on the effect of the independent variable on the dependent. Every experiment has a controlling variable, and it is necessary to not change it, or the results of the experiment won't be valid",study design controlled variable,,"In a study in which gene expression is measured in patients between 8 month to 4 years old that have mild or severe malaria and in which the hypothesis is that gene expression in that age group is a function of disease status, age is a controlled variable.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0500000,OBI:0000785,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,study design controlled variable,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Alan Ruttenberg|PERSON: Bjoern Peters|PERSON: Chris Stoeckert,,
http://purl.obolibrary.org/obo/OBI_0500003,cross over design,,"a repeated measure design which ensures that experimental units receive, in sequence, the treatment (or the control), and then, after a specified time interval (aka *wash-out periods*), switch to the control (or treatment). In this design, subjects (patients in human context) serve as their own controls, and randomization may be used to determine the ordering which a subject receives the treatment and control",false,,,http://purl.obolibrary.org/obo/OBI_0500002,,,,,,,,,,,,,,,,,,,"a repeated measure design which ensures that experimental units receive, in sequence, the treatment (or the control), and then, after a specified time interval (aka *wash-out periods*), switch to the control (or treatment). In this design, subjects (patients in human context) serve as their own controls, and randomization may be used to determine the ordering which a subject receives the treatment and control",(source: http://www.sbu.se/Filer/Content0/publikationer/1/literaturesearching_1993/glossary.html),,,,,,cross over design,,"PMID: 17601993-Objective: HIV-infected patients with lipodystrophy (HIV-lipodystrophy) are insulin resistant and have elevated plasma free fatty acid (FFA) concentrations. We aimed to explore the mechanisms underlying FFA-induced insulin resistance in patients with HIV-lipodystrophy. Research Design and Methods: Using a randomized placebo-controlled cross-over design, we studied the effects of an overnight acipimox-induced suppression of FFA on glucose and FFA metabolism by using stable isotope labelled tracer techniques during basal conditions and a two-stage euglycemic, hyperinsulinemic clamp (20 mU insulin/m(2)/min; 50 mU insulin/m(2)/min) in nine patients with nondiabetic HIV-lipodystrophy. All patients received antiretroviral therapy. Biopsies from the vastus lateralis muscle were obtained during each stage of the clamp. Results: Acipimox treatment reduced basal FFA rate of appearance by 68.9% (52.6%-79.5%) and decreased plasma FFA concentration by 51.6 % (42.0%-58.9%), (both, P < 0.0001). Endogenous glucose production was not influenced by acipimox. During the clamp the increase in glucose-uptake was significantly greater after acipimox treatment compared to placebo (acipimox: 26.85 (18.09-39.86) vs placebo: 20.30 (13.67-30.13) mumol/kg/min; P < 0.01). Insulin increased phosphorylation of Akt (Thr(308)) and GSK-3beta (Ser(9)), decreased phosphorylation of glycogen synthase (GS) site 3a+b and increased GS-activity (I-form) in skeletal muscle (P < 0.01). Acipimox decreased phosphorylation of GS (site 3a+b) (P < 0.02) and increased GS-activity (P < 0.01) in muscle. Conclusion: The present study provides direct evidence that suppression of lipolysis in patients with HIV-lipodystrophy improves insulin-stimulated peripheral glucose-uptake. The increased glucose-uptake may in part be explained by increased dephosphorylation of GS (site 3a+b) resulting in increased GS activity.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0500003,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cross over design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001219,epitope specific chemokine (C-C motif) ligand 1 production by T cells,,A process of chemokine (C-C motif) ligand 1 production by T cells resulting from the recognition of a T cell epitope.,false,,,http://purl.obolibrary.org/obo/GO_0071610|http://purl.obolibrary.org/obo/OBI_0001193,,,,,,,,,,,,,,,,,Date: 2011-04-01; Spreadsheet: All AssayTypes.xls; Worksheet: E specific Template; Mapping: e_specific_mappings.owl,,A process of chemokine (C-C motif) ligand 1 production by T cells resulting from the recognition of a T cell epitope.,IEDB (QTT),,,,,,epitope specific chemokine (C-C motif) ligand 1 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001219,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,epitope specific chemokine (C-C motif) ligand 1 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/BFO_0000020,specifically dependent continuant,,"A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.|b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n &gt; 1 independent continuants c1, … cn which are not spatial regions are such that for all 1  i &lt; j  n, ci  and cj share no common parts, are such that for each 1  i  n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004])|b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])",false,,,http://purl.obolibrary.org/obo/BFO_0000002,,,,,,,SpecificallyDependentContinuant,sdc,,,,,,,,,,,"A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.|b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n &gt; 1 independent continuants c1, … cn which are not spatial regions are such that for all 1  i &lt; j  n, ci  and cj share no common parts, are such that for each 1  i  n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004])|b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])",,,,,,"Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc.",specifically dependent continuant,,"the mutual dependence of proton donors and acceptors in chemical reactions [79|the pink color of a medium rare piece of grilled filet mignon at its center|the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction|of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates.|the shape of this hole.|the role of being a doctor|the function of this heart: to pump blood|the smell of this portion of mozzarella|of one-sided specifically dependent continuants: the mass of this tomato|the disposition of this fish to decay|Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key",,,,,,,,(iff (RelationalSpecificallyDependentContinuant a) (and (SpecificallyDependentContinuant a) (forall (t) (exists (b c) (and (not (SpatialRegion b)) (not (SpatialRegion c)) (not (= b c)) (not (exists (d) (and (continuantPartOfAt d b t) (continuantPartOfAt d c t)))) (specificallyDependsOnAt a b t) (specificallyDependsOnAt a c t)))))) // axiom label in BFO2 CLIF: [131-004] |(iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BFO:0000020,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/bfo.owl,,,,,,,,,,,,,,,,,,,,,,,,,,,specifically dependent continuant,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200172,partitioning objective,,A partitioning objective is a data transformation objective where the aim is to generate a collection of disjoint non-empty subsets whose union equals a non-empty input set.,false,,,http://purl.obolibrary.org/obo/OBI_0200166,,,,,,,,,,,,,,,,,,,A partitioning objective is a data transformation objective where the aim is to generate a collection of disjoint non-empty subsets whose union equals a non-empty input set.,PERSON: Elisabetta Manduchi,,,,,,partitioning objective,,A k-means clustering which has partitioning objective is a data transformation in which the input data is partitioned into k output sets.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200172,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,partitioning objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0400086,plate loader,,Part of the fluidics system. A plate loader positions the wells of a multi-well plate under the aspiration tube is a preset order. A plate loader is used for high throughput applications.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,Part of the fluidics system. A plate loader positions the wells of a multi-well plate under the aspiration tube is a preset order. A plate loader is used for high throughput applications.,http://www.beckmancoulter.com/literature/Bioresearch/P-10202A.pdf,,,,,measurement function is not corret as discussed on April 26 dev call. Will add new function such as positioning function. Add to tracker will discuss in the future.,plate loader,,FC 500 plate loader,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000383,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400086,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,plate loader,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0000214,negative reference substance role,negative reference substance,"a reference role in which the characteristics or responses elicited by the substance playing the reference substance role are used to establish a ""no effect"" response",false,,,http://purl.obolibrary.org/obo/OBI_0000025,,,,negative reference substance,,,,,,,,,,,,,,,"a reference role in which the characteristics or responses elicited by the substance playing the reference substance role are used to establish a ""no effect"" response",,,,,,,negative reference substance role,,Saline solution,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000214,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,negative reference substance role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person: Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0001496,intracellular cytokine staining assay measuring epitope specific interleukin-22 production by T cells,IL-22 release|ICS,An assay of epitope specific interleukin-22 production by T cells that uses an intracellular cytokine staining assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001217,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-22 production by T cells that uses an intracellular cytokine staining assay.,IEDB,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-22 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001496,,,,,,,,,,,,,,,,,,,,,,,,IL-22 release|ICS,,,,,,,,,,,,,,,,,,,,,,intracellular cytokine staining assay measuring epitope specific interleukin-22 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000682,obsolete_study result,,Study result is an information content entity  that is a specified data output of a study.,true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,2009-02-28: work on this term has been finalized during the OBI workshop winter 2009,,Study result is an information content entity  that is a specified data output of a study.,GROUP: OBI,,,,,,obsolete_study result,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000230,,,,,,,,,,,,,,,,,,OBI:0000682,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_study result,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0000394,blot module,,A blot module is a device which has the function to conatin and facilitate the material transfer process blotting to be realised,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A blot module is a device which has the function to conatin and facilitate the material transfer process blotting to be realised,sep:00092,,,,,,blot module,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000383,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000394,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,blot module,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Frank Gibson,,
http://purl.obolibrary.org/obo/OBI_1000049,whole mount tissue,whole mount sample,A whole organism preparation resulting from a histological preparation known as whole mount preparation where the whole specimen is mounted or spread on the microscope (glass) slide,false,,,http://purl.obolibrary.org/obo/OBI_0000680|http://purl.obolibrary.org/obo/OBI_0001479|http://purl.obolibrary.org/obo/OBI_0000953,,,,whole mount sample,,,,,,,,,,,,,PRS:22-02-2008: is a material which has output_role during whole mount preparation protocol-application|PRS:22-02-2008: indicates the need to create a protocol application and distinguish it from this entity,,A whole organism preparation resulting from a histological preparation known as whole mount preparation where the whole specimen is mounted or spread on the microscope (glass) slide,GROUP: OBI,,http://purl.obolibrary.org/obo/CARO_0001008,,,,whole mount tissue,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1000049,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000341,,,whole mount tissue,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Helen Parkinson|PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001664,intracellular material detection assay measuring epitope specific granulysin release by T cells,granulysin release|intracellular staining,A T cell epitope specific granulysin release assay that uses an intracellular material detection by flow cytometry assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001810,,,,,,,,,,,,,,,,,,,A T cell epitope specific granulysin release assay that uses an intracellular material detection by flow cytometry assay.,IEDB,,,,,,intracellular material detection assay measuring epitope specific granulysin release by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001664,,,,,,,,,,,,,,,,,,,,,,,,granulysin release|intracellular staining,,,,,,,,,,,,,,,,,,,,,,intracellular material detection assay measuring epitope specific granulysin release by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000971,fresh specimen,,a specimen that is output of a specimen creation process used for an investigation without storage.,false,,,http://purl.obolibrary.org/obo/OBI_0001472,,,,,,,,,,,,,,,,,,,a specimen that is output of a specimen creation process used for an investigation without storage.,MO_730 fresh_sample,,,,,,fresh specimen,,a liver freshly removed from a rat,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000971,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,fresh specimen,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Chris Stoeckert|PERSON: Jie Zheng,,
http://purl.obolibrary.org/obo/CHEBI_15377,water,,An inorganic hydroxy compound that has formula H2O.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,An inorganic hydroxy compound that has formula H2O.,,,,,,,water,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:15377,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,water,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001790,ELISPOT assay measuring epitope specific RANTES production by T cells,CCL5/RANTES release|ELISPOT,An assay of epitope specific RANTES production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001232,,,,,,,,,,,,,,,,,,,An assay of epitope specific RANTES production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific RANTES production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001790,,,,,,,,,,,,,,,,,,,,,,,,CCL5/RANTES release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific RANTES production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/CLO_0009828,immortal cell line,,A cell line that is expected to be capable of indefinite propagation in an vitro culture.,false,,,http://purl.obolibrary.org/obo/CLO_0000031,,,,,,,,,,,,,,,,,,,A cell line that is expected to be capable of indefinite propagation in an vitro culture.,,,,,,,immortal cell line,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CLO_0000019,,,,,,,,,,,,,,,,,,,,,,,,,,,CLO:0009828,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/clo.owl,,,,,,,,,,,,,,,,,,,immortal cell line,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001751,ELISA measuring epitope specific interferon-beta production by T cells,IFNb release|ELISA,An assay of epitope specific interferon-beta production by T cells that uses an ELISA.,false,,,http://purl.obolibrary.org/obo/OBI_0001390,,,,,,,,,,,,,,,,,,,An assay of epitope specific interferon-beta production by T cells that uses an ELISA.,IEDB,,,,,,ELISA measuring epitope specific interferon-beta production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001751,,,,,,,,,,,,,,,,,,,,,,,,IFNb release|ELISA,,,,,,,,,,,,,,,,,,,,,,ELISA measuring epitope specific interferon-beta production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0666666,RNA extraction,,A RNA extraction is a nucleic acid extraction where the desired output material is RNA,false,,,http://purl.obolibrary.org/obo/OBI_0666667,,,,,,,,,,,,,,,,,requested by Helen Parkinson for MO,,A RNA extraction is a nucleic acid extraction where the desired output material is RNA,OBI branch derived,,,,,,RNA extraction,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/CHEBI_33697,,,OBI:0666666,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,RNA extraction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PlanAndPlannedProcess Branch,,
http://purl.obolibrary.org/obo/OBI_0100069,obsolete_polymer,,"A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.",true,,,http://www.geneontology.org/formats/oboInOwl#ObsoleteClass,,,,,,,,,,,,,,,,,,,"A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.",TERM: CHEBI:33839,,,,,"MC, 20100316: Replaced by Chebi polymer and usage polymerization also fixed.",obsolete_polymer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000228,,,,,,,,,,,,,,,,,,OBI:0100069,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obsolete_polymer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/IAO_0000179,histogram,,"A histogram is a report graph which is a statistical description of a
distribution in terms of occurrence frequencies of different event classes.",false,,,http://purl.obolibrary.org/obo/IAO_0000038,,,,,,,,,,,,,,,,,,,"A histogram is a report graph which is a statistical description of a
distribution in terms of occurrence frequencies of different event classes.",GROUP:OBI,,,,,,histogram,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IAO:0000179,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,histogram,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:James Malone|PERSON:Chris Stoeckert|PERSON:Melanie Courtot,,
http://purl.obolibrary.org/obo/OBI_0001729,quenching assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex,dissociation constant KD|quenching|nM,A B cell epitope equilibrium dissociation constant (KD) determination assay that uses an antibody binding detection by fluorescence quenching assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001499|http://purl.obolibrary.org/obo/OBI_0001708,,,,,,,,,,,,,,,,,,,A B cell epitope equilibrium dissociation constant (KD) determination assay that uses an antibody binding detection by fluorescence quenching assay.,IEDB,,,,,,quenching assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001729,,,,,,,,,,,,,,,,,,,,,,,,dissociation constant KD|quenching|nM,,,,,,,,,,,,,,,,,,,,,,quenching assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0000458,manufacturing objective,,is the objective to manufacture a material of a certain function (device),false,,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,,,is the objective to manufacture a material of a certain function (device),GROUP: OBI PlanAndPlannedProcess Branch,,,,,,manufacturing objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000458,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,manufacturing objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Melanie Courtot|PERSON: Jennifer Fostel|PERSON: Frank Gibson|PERSON: Bjoern Peters|PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0001772,biological activity assay measuring epitope specific interleukin-17F production by T cells,IL-17F release|biological activity,An assay of epitope specific interleukin-17 production by T cells that detects interleukin-17F production.,false,,,http://purl.obolibrary.org/obo/OBI_0001295,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-17 production by T cells that detects interleukin-17F production.,IEDB,,,,,,biological activity assay measuring epitope specific interleukin-17F production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001772,,,,,,,,,,,,,,,,,,,,,,,,IL-17F release|biological activity,,,,,,,,,,,,,,,,,,,,,,biological activity assay measuring epitope specific interleukin-17F production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001069,array manufacturer role,,a manufacturer role which is played by the person or organization that manufactured the array,false,,,http://purl.obolibrary.org/obo/OBI_0000571,,,,,,,,,,,,,,,,,,,a manufacturer role which is played by the person or organization that manufactured the array,MO_695 array_manufacturer,,,,,,array manufacturer role,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001069,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,array manufacturer role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/CHEBI_17137,hydrogensulfite,,A sulfur oxoanion that has formula HO3S.,false,,,http://purl.obolibrary.org/obo/CHEBI_23367,,,,,,,,,,,,,,,,,,,A sulfur oxoanion that has formula HO3S.,,,,,,,hydrogensulfite,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CHEBI:17137,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/chebi.owl,,,,,,,,,,,,,,,,,,,hydrogensulfite,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0002055,assay measuring T cell epitope specific biological activity,biological activity|any method,A T cell epitope recognition assay that detects biological activity.,false,,,http://purl.obolibrary.org/obo/OBI_1110037,,,,,,,,,,,,,,,,,,,A T cell epitope recognition assay that detects biological activity.,IEDB,,,,,,assay measuring T cell epitope specific biological activity,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002055,,,,,,,,,,,,,,,,,,,,,,,,biological activity|any method,,,,,,,,,,,,,,,,,,,,,,assay measuring T cell epitope specific biological activity,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0002053,microarray assay measuring binding of a B cell epitope:antibody complex,qualitative binding|microarray,A B cell epitope qualitative binding to antibody assay that uses a microarray.,false,,,http://purl.obolibrary.org/obo/OBI_0001703,,,,,,,,,,,,,,,,,,,A B cell epitope qualitative binding to antibody assay that uses a microarray.,IEDB,,,,,,microarray assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002053,,,,,,,,,,,,,,,,,,,,,,,,qualitative binding|microarray,,,,,,,,,,,,,,,,,,,,,,microarray assay measuring binding of a B cell epitope:antibody complex,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0400118,vortexer,vortex_mixer,A vortexer is an instrument that mixes small vials of liquid by creating a rotation of the liquid around its own center. It consists of an electric motor with the drive shaft oriented vertically and attached to a cupped rubber piece mounted slightly off-center. As the motor runs the rubber piece oscillates rapidly in a circular motion. When a test tube or other appropriate container is pressed into the rubber cup (or touched to its edge) the motion is transmitted to the liquid inside and a vortex is created.,false,,,http://purl.obolibrary.org/obo/OBI_0001033,,,,vortex_mixer,,,,,,,,,,,,,,,A vortexer is an instrument that mixes small vials of liquid by creating a rotation of the liquid around its own center. It consists of an electric motor with the drive shaft oriented vertically and attached to a cupped rubber piece mounted slightly off-center. As the motor runs the rubber piece oscillates rapidly in a circular motion. When a test tube or other appropriate container is pressed into the rubber cup (or touched to its edge) the motion is transmitted to the liquid inside and a vortex is created.,http://en.wikipedia.org/wiki/Vortex_mixer,,,,,,vortexer,,VWR  Genie 2,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,http://purl.obolibrary.org/obo/OBI_0000377,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400118,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,vortexer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Melanie Courtot|Trish Whetzel,,
http://purl.obolibrary.org/obo/PR_P61244,PR_P61244,,,false,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PR:P61244,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001279,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-22 production by T cells,IL-22 release|RNA/DNA detection,An assay of epitope specific interleukin-22 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001217,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-22 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-22 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001279,,,,,,,,,,,,,,,,,,,,,,,,IL-22 release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-22 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0302896,cervical dislocation,,cervical dislocation is a process by which a Vertebrate organism has its life terminated by rupturing spinal cord between cervical vertebrae induced by excessive mechanical torsion,false,,,http://purl.obolibrary.org/obo/OBI_0000919,,,,,,,,,,,,,,,,,,,cervical dislocation is a process by which a Vertebrate organism has its life terminated by rupturing spinal cord between cervical vertebrae induced by excessive mechanical torsion,OBI branch,,,,,PRS:21102008: Input must be restricted to Vertebrates (requires import from NCBI tax),cervical dislocation,,"PMID: 18246869. Loss of cortical function in mice after decapitation, cervical dislocation, potassium chloride injection, and CO2 inhalation. Comp Med. 2007 Dec;57(6):570-3",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0302896,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,cervical dislocation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0200099,discriminant function analysis,,Discriminant function analysis is a form of discriminant analysis used to determine which variables discriminate between two or more naturally occurring groups. Analysis is used to determine which variable(s) are the best predictors of a particular outcome.,false,,,http://purl.obolibrary.org/obo/OBI_0200106|http://purl.obolibrary.org/obo/OBI_0200175|http://purl.obolibrary.org/obo/OBI_0000663,,,,,,,,,,,,,,,,,,,Discriminant function analysis is a form of discriminant analysis used to determine which variables discriminate between two or more naturally occurring groups. Analysis is used to determine which variable(s) are the best predictors of a particular outcome.,WEB: http://www.statsoft.com/textbook/stdiscan.html,,,,,,discriminant function analysis,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000648,,,OBI:0200099,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,discriminant function analysis,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Tina Hernandez-Boussard,,
http://purl.obolibrary.org/obo/OBI_0000423,extract,extracted material,an extract is a material entity which results from an extraction process,false,,,http://purl.obolibrary.org/obo/OBI_0000047,,,,extracted material,,,,,,,,,,,,,,,an extract is a material entity which results from an extraction process,GROUP: OBI Biomatrial Branch,,,,,,extract,,Up-regulation of inflammatory signalings by areca nut extract and role of cyclooxygenase-2 -1195G>a polymorphism reveal risk of oral cancer. Cancer Res. 2008 Oct 15;68(20):8489-98. PMID: 18922923,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000423,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0302884,,,extract,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000129,calibration substance role,,A reference substance role that is realized when characteristics or responses elicited by the bearer are used to ensure an instrument is within protocol specification of accuracy or performance,false,,,http://purl.obolibrary.org/obo/OBI_0000025,,,,,,,,,,,,,,,,,,,A reference substance role that is realized when characteristics or responses elicited by the bearer are used to ensure an instrument is within protocol specification of accuracy or performance,,,,,,,calibration substance role,,pH buffer used to calibrate a pH meter bears a calibration substance role,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000129,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,calibration substance role,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Jennifer Fostel,,
http://purl.obolibrary.org/obo/OBI_0001861,methylation-sensitive restriction enzyme sequencing assay,MRE-seq assay|MRE-seq,An assay that identifies unmethylated CpGs by  use of methylation sensitive restriction enzymes to fragment DNA.,false,,,http://purl.obolibrary.org/obo/OBI_0001266|http://purl.obolibrary.org/obo/OBI_0000626,,http://purl.obolibrary.org/obo/OBI_0001234,,MRE-seq assay|MRE-seq,,,,,,,,,,,,,,,An assay that identifies unmethylated CpGs by  use of methylation sensitive restriction enzymes to fragment DNA.,Maunakea et al. Conserved role of intragenic DNA methylation in regulating alternative promoters. Nature. 2010 Jul 8;466(7303):253-7. [PMID:20613842],,,,,,methylation-sensitive restriction enzyme sequencing assay,,Maunakea et al. Conserved role of intragenic DNA methylation in regulating alternative promoters. Nature. 2010 Jul 8;466(7303):253-7. [PMID:20613842],,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000711|http://purl.obolibrary.org/obo/OBI_0600050|http://purl.obolibrary.org/obo/OBI_0000626,http://purl.obolibrary.org/obo/OBI_0400103,,,,,,,,,,,,,,,OBI:0001861,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,methylation-sensitive restriction enzyme sequencing assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0002042,carbon-copy chromosome conformation capture assay followed by sequencing assay,Carbon-copy chromosome conformation capture assay followed by sequencing|HiC|HiC assay,"A carbon-copy chromosome conformation capture assay to analyze the organization of chromosomes in an unbiased, genome-wide manner using high throughput sequening following carbon-copy chromosome conformation capture.",false,,,http://purl.obolibrary.org/obo/OBI_0001919,,,,Carbon-copy chromosome conformation capture assay followed by sequencing|HiC|HiC assay,,,,,,,,,,,,,,,"A carbon-copy chromosome conformation capture assay to analyze the organization of chromosomes in an unbiased, genome-wide manner using high throughput sequening following carbon-copy chromosome conformation capture.","Lieberman-Aiden E, et al. (2009). Comprehensive mapping of long-range interactions reveals folding principles of the human genome. Science 326: 289-293.",,,,,,carbon-copy chromosome conformation capture assay followed by sequencing assay,,"Fudenberg et al., (November 2014). ""High order chromatin architecture shapes the landscape of chromosomal alterations in cancer."" Nat Biotechol 29(12):1109-13. doi: 10.1038/nbt.2049.",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002042,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,carbon-copy chromosome conformation capture assay followed by sequencing assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,ENCODE project,,,,,,,,"Person: Venkat Malladi, Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/SO_0000148,supercontig,,One or more contigs that have been ordered and oriented using end-read information. Contains gaps that are filled with N's.,false,,,http://purl.obolibrary.org/obo/SO_0000353,,,,,,,,,,,,,,,,,,,One or more contigs that have been ordered and oriented using end-read information. Contains gaps that are filled with N's.,,,,,,,supercontig,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,SO:0000148,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/so.owl,,,,,,,,,,,,,,,,,,,supercontig,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/SO_0000149,contig,,"A contiguous sequence derived from sequence assembly. Has no gaps, but may contain N's from unavailable bases.",false,,,http://purl.obolibrary.org/obo/SO_0000353,,,,,,,,,,,,,,,,,,,"A contiguous sequence derived from sequence assembly. Has no gaps, but may contain N's from unavailable bases.",,,,,,,contig,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,SO:0000149,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/so.owl,,,,,,,,,,,,,,,,,,,contig,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001141,individual organism identifier,,a CRID symbol used to distinguish one individual organism from another.,false,,,http://purl.obolibrary.org/obo/IAO_0000577,,,,,,,,,,,,,,,,,,,a CRID symbol used to distinguish one individual organism from another.,MO_169 Individual,,,,,,individual organism identifier,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001141,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,individual organism identifier,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/OBI_0200058,b cell epitope prediction,,"A B cell epitope prediction takes as input an antigen sequence, and through an analysis of this sequence, produces as output a prediction of the likelihood the biomaterial is a B Cell Epitope.",false,,,http://purl.obolibrary.org/obo/OBI_0200187,,http://purl.obolibrary.org/obo/OBI_0200081,,,,,,,,,,,,,,,,,"A B cell epitope prediction takes as input an antigen sequence, and through an analysis of this sequence, produces as output a prediction of the likelihood the biomaterial is a B Cell Epitope.",PERSON: Helen Parkinson,,,,,,b cell epitope prediction,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200058,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,b cell epitope prediction,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0001124,micropipette puller,,A device that is used to fabricate glass micropipettes.,false,,,http://purl.obolibrary.org/obo/OBI_0000968,,,,,,,,,,,,,,,,,,,A device that is used to fabricate glass micropipettes.,http://en.wikipedia.org/wiki/Micropipette,,,,,,micropipette puller,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000379,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001124,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,micropipette puller,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Erik Segerdell,,
http://purl.obolibrary.org/obo/OBI_0000586,plunger column,,A plunger column is a chromatography column with adjustable heigth control. By means of an adjustable endpiece (plunger) the user can adjust the column length without disturbing the packed bed. Plunger columns can equalize volume changes and thus avoids dead volumes within the column.,false,,,http://purl.obolibrary.org/obo/OBI_0000038,,,,,,,,,,,,,,,,,,,A plunger column is a chromatography column with adjustable heigth control. By means of an adjustable endpiece (plunger) the user can adjust the column length without disturbing the packed bed. Plunger columns can equalize volume changes and thus avoids dead volumes within the column.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01108,,,,,,plunger column,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000586,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,plunger column,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/PATO_0001196,ventral to,,A spatial quality inhering in a bearer by virtue of the bearer's being located toward the abdomen of an organism relative to another entity.,false,,,http://purl.obolibrary.org/obo/PATO_0001631,,,,,,,,,,,,,,,,,,,A spatial quality inhering in a bearer by virtue of the bearer's being located toward the abdomen of an organism relative to another entity.,,,,,,,ventral to,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001196,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,ventral to,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0001193,lateral to,,A spatial quality inhering in a bearer by virtue of the bearer's being located toward the side relative to another entity.,false,,,http://purl.obolibrary.org/obo/PATO_0001631,,,,,,,,,,,,,,,,,,,A spatial quality inhering in a bearer by virtue of the bearer's being located toward the side relative to another entity.,,,,,,,lateral to,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0001193,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,lateral to,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200034,jackknifing method,jackknifing,Jacknifing is a re-sampling data transformation process used to estimate the precision of sampling statistics and is a resampling method,false,,,http://purl.obolibrary.org/obo/OBI_0000792,,http://purl.obolibrary.org/obo/OBI_0200188,,jackknifing,,,,,,,,,,,,,,,Jacknifing is a re-sampling data transformation process used to estimate the precision of sampling statistics and is a resampling method,http://en.wikipedia.org/wiki/Resampling_%28statistics%29,,,,,,jackknifing method,,"simple weighting procedure is suggested for combining information over alleles and loci, and sample variances may be estimated by a jackknife procedure",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200034,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,jackknifing method,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Helen Parkinson,,
http://purl.obolibrary.org/obo/PATO_0000384,male,,A biological sex quality inhering in an individual or a population whose sex organs contain only male gametes.,false,,,http://purl.obolibrary.org/obo/PATO_0000047,,,,,,,,,,,,,,,,,,,A biological sex quality inhering in an individual or a population whose sex organs contain only male gametes.,,,,,,,male,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0000384,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,male,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PATO_0000383,female,,A biological sex quality inhering in an individual or a population that only produces gametes that can be fertilised by male gametes.,false,,,http://purl.obolibrary.org/obo/PATO_0000047,,,,,,,,,,,,,,,,,,,A biological sex quality inhering in an individual or a population that only produces gametes that can be fertilised by male gametes.,,,,,,,female,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PATO:0000383,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pato.owl,,,,,,,,,,,,,,,,,,,female,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0200173,background correction objective,,"A background correction objective is a data transformation objective where the aim is to remove irrelevant contributions from the measured signal, e.g. those due to instrument noise or sample preparation.",false,,,http://purl.obolibrary.org/obo/OBI_0200168,,,,,,,,,,,,,,,,,,,"A background correction objective is a data transformation objective where the aim is to remove irrelevant contributions from the measured signal, e.g. those due to instrument noise or sample preparation.",PERSON: Elisabetta Manduchi,,,,,,background correction objective,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000125,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0200173,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,background correction objective,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,James Malone|Elisabetta Manduchi,,
http://purl.obolibrary.org/obo/OBI_0200066,Holm-Bonferroni family-wise error rate correction method,,"a data transformation that performs more than one hypothesis test simultaneously, a closed-test procedure, that  controls the familywise error rate for all the k hypotheses at level α in the strong sense. Objective: multiple testing correction",false,,,http://purl.obolibrary.org/obo/OBI_0200073,,http://purl.obolibrary.org/obo/OBI_0000791,,,,,,,,,,,,,,,,,"a data transformation that performs more than one hypothesis test simultaneously, a closed-test procedure, that  controls the familywise error rate for all the k hypotheses at level α in the strong sense. Objective: multiple testing correction",WEB: http://en.wikipedia.org/wiki/Holm%E2%80%93Bonferroni_method,,,,,"2011-03-14: [PRS]. Class Label has been changed to address the conflict with the definition
Also added restriction to specify the output to be a FWER adjusted p-value

The 'editor preferred term' should be removed",Holm-Bonferroni family-wise error rate correction method,,"t-tests were used with the type I error adjusted for multiple comparisons, Holm's correction (HOLM 1979), and false discovery rate, http://www.genetics.org/cgi/content/full/172/2/1179",,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000175,http://purl.obolibrary.org/obo/OBI_0001265,,,OBI:0200066,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Holm-Bonferroni family-wise error rate correction method,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Philippe Rocca-Serra|Person:Helen Parkinson,,
http://purl.obolibrary.org/obo/OBI_0400009,arc lamp,,"Arc lamp is a light source that produces light by an electric arc (or voltaic arc). The lamp consists of two electrodes typically made of tungsten which are separated by a gas. The type of lamp is often named by the gas contained in the bulb; including neon, argon, xenon, krypton, sodium, metal halide, and mercury. The electric arc in an arc lamp consists of gas which is initially ionized by a voltage and is therefore electrically conductive. To start an arc lamp, usually a very high voltage is needed to ignite or strike the arc. This requires an electrical circuit sometimes called an igniter, which is part of a larger circuit called the ballast. The ballast supplies a suitable voltage and current to the lamp as its electrical characteristics change with temperature and time. Older cytometers may use arc lamps to irradiate particles at the interrogation point.",false,,,http://purl.obolibrary.org/obo/OBI_0400065,,,,,,,,,,,,,,,,,,,"Arc lamp is a light source that produces light by an electric arc (or voltaic arc). The lamp consists of two electrodes typically made of tungsten which are separated by a gas. The type of lamp is often named by the gas contained in the bulb; including neon, argon, xenon, krypton, sodium, metal halide, and mercury. The electric arc in an arc lamp consists of gas which is initially ionized by a voltage and is therefore electrically conductive. To start an arc lamp, usually a very high voltage is needed to ignite or strike the arc. This requires an electrical circuit sometimes called an igniter, which is part of a larger circuit called the ballast. The ballast supplies a suitable voltage and current to the lamp as its electrical characteristics change with temperature and time. Older cytometers may use arc lamps to irradiate particles at the interrogation point.",http://en.wikipedia.org/wiki/Arc_lamp,,,,,,arc lamp,,The Jablochkoff Candle,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400009,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,arc lamp,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0000534,tecmag NMR instrument,,An NMR instrument that is manufactured by tecmag.,false,,,http://purl.obolibrary.org/obo/OBI_0000566,,,,,,,,,,,,,,,,,NMR instrument,,An NMR instrument that is manufactured by tecmag.,GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400250,,,,,,tecmag NMR instrument,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000534,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,tecmag NMR instrument,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001206,ELISPOT assay measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells,GM-CSF release|ELISPOT,An assay of epitope specific granulocyte macrophage colony stimulating factor production by T cells that uses an ELISPOT assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001233,,,,,,,,,,,,,,,,,,,An assay of epitope specific granulocyte macrophage colony stimulating factor production by T cells that uses an ELISPOT assay.,IEDB,,,,,,ELISPOT assay measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001206,,,,,,,,,,,,,,,,,,,,,,,,GM-CSF release|ELISPOT,,,,,,,,,,,,,,,,,,,,,,ELISPOT assay measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0400078,obscuration bar,,An obscuration bar is a an optical subsystem which is a strip of metal or other material that serves to block out direct light from the illuminating beam. The obscuration bar prevents the bright light scattered in the forward directions from burning out the collection device.,false,,,http://purl.obolibrary.org/obo/OBI_0000932,,,,,,,,,,,,,,,,,,,An obscuration bar is a an optical subsystem which is a strip of metal or other material that serves to block out direct light from the illuminating beam. The obscuration bar prevents the bright light scattered in the forward directions from burning out the collection device.,"John Quinn|Flow Cytometry: First Principles, by Alice Longobardi Givan, ISBN-10: 0471382248, ISBN-13: 978-0471382249",,,,,,obscuration bar,,obscuration bar in a flow cytometer,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,http://purl.obolibrary.org/obo/OBI_0000378,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400078,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,obscuration bar,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001325,detection of specific nucleic acids with complementary probes assay measuring epitope specific RANTES production by T cells,CCL5/RANTES release|RNA/DNA detection,An assay of epitope specific RANTES production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001232,,,,,,,,,,,,,,,,,,,An assay of epitope specific RANTES production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific RANTES production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001325,,,,,,,,,,,,,,,,,,,,,,,,CCL5/RANTES release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific RANTES production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0002068,cytometric bead array assay measuring epitope specific oncostatin M production by T cells,oncostatin M release|cytometric bead array,An assay of epitope specific oncostatin M production by T cells that uses a cytometric bead array assay.,false,,,http://purl.obolibrary.org/obo/OBI_0002058,,,,,,,,,,,,,,,,,,,An assay of epitope specific oncostatin M production by T cells that uses a cytometric bead array assay.,IEDB,,,,,,cytometric bead array assay measuring epitope specific oncostatin M production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0002068,,,,,,,,,,,,,,,,,,,,,,,,oncostatin M release|cytometric bead array,,,,,,,,,,,,,,,,,,,,,,cytometric bead array assay measuring epitope specific oncostatin M production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0001956,assay using chromatin immunoprecipitation,,an assay which uses immunoprecipitation and which produces data about protein-DNA interaction or DNA epigenetic modification,false,,,http://purl.obolibrary.org/obo/OBI_0001700,,,,,,,,,,,,,,,,,,,an assay which uses immunoprecipitation and which produces data about protein-DNA interaction or DNA epigenetic modification,,,,,,"as per user (pployd) request and proposal by Alan Ruttenberg
http://sourceforge.net/p/obi/obi-terms/707/",assay using chromatin immunoprecipitation,,http://www.lifetechnologies.com/uk/en/home/life-science/epigenetics-noncoding-rna-research/chromatin-remodeling/chromatin-immunoprecipitation-chip.html,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001956,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,assay using chromatin immunoprecipitation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON: Philippe Rocca-Serra,,
http://purl.obolibrary.org/obo/OBI_0000505,multiple wavelength detector,,"A chromatography detector, that can detect many discrete wavelengths in parallel and produces a multiple wavelength chromatographic profile.",false,,,http://purl.obolibrary.org/obo/OBI_0000832,,,,,,,,,,,,,,,,,,,"A chromatography detector, that can detect many discrete wavelengths in parallel and produces a multiple wavelength chromatographic profile.",GROUP:<http://msi-ontology.sourceforge.net>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01078,,,,,,multiple wavelength detector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,http://purl.obolibrary.org/obo/OBI_0000453,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000505,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,multiple wavelength detector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0000642,atomic emission detector,AED,"Instead of measuring simple gas phase (carbon containing) ions created in a flame as with the flame ionization detector, or the change in background current because of electronegative element capture of thermal electrons as with the electron capture detector, the AED has a much wider applicability because it is based on the detection of atomic emissions. The strength of the AED lies in the detector's ability to simultaneously determine the atomic emissions of many of the elements in analytes that elute from a GC capillary column (called eluants or solutes in some books). As eluants come off the capillary column they are fed into a microwave powered plasma (or discharge) cavity where the compounds are destroyed and their atoms are excited by the energy of the plasma. The light that is emitted by the excited particles is separated into individual lines via a photodiode array. The associated computer then sorts out the individual emission lines and can produce chromatograms made up of peaks from eluants that contain only a specific element.",false,,,http://purl.obolibrary.org/obo/OBI_0000637,,,,AED,,,,,,,,,,,,,,,"Instead of measuring simple gas phase (carbon containing) ions created in a flame as with the flame ionization detector, or the change in background current because of electronegative element capture of thermal electrons as with the electron capture detector, the AED has a much wider applicability because it is based on the detection of atomic emissions. The strength of the AED lies in the detector's ability to simultaneously determine the atomic emissions of many of the elements in analytes that elute from a GC capillary column (called eluants or solutes in some books). As eluants come off the capillary column they are fed into a microwave powered plasma (or discharge) cavity where the compounds are destroyed and their atoms are excited by the energy of the plasma. The light that is emitted by the excited particles is separated into individual lines via a photodiode array. The associated computer then sorts out the individual emission lines and can produce chromatograms made up of peaks from eluants that contain only a specific element.",WEB:<http://elchem.kaist.ac.kr/vt/chem-ed/sep/gc/detector/aed.htmt>|http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01086,,,,,,atomic emission detector,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000642,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,atomic emission detector,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0400048,Guava EasyCyte Mini,,"A Guava_EasyCyte_Mini is a flow_cytometer_analyser that includes a single 488 nm laser, and filters and PMTs to collect up to 3 fluorescent parameters. It includes a photodiode forward scatter collector and an optional photodiode for side scatter collection.Guava cytometers use aspiration instead of fluid systems to transport cells within the machine. The mini accepts tubes only for inputting cells or beads. The Guava_EasyCyte_Mini cytometer is a small portable cytometer particularly useful for field measurement.",false,,,http://purl.obolibrary.org/obo/OBI_0400008,,,,,,,,,,,,,,,,,,,"A Guava_EasyCyte_Mini is a flow_cytometer_analyser that includes a single 488 nm laser, and filters and PMTs to collect up to 3 fluorescent parameters. It includes a photodiode forward scatter collector and an optional photodiode for side scatter collection.Guava cytometers use aspiration instead of fluid systems to transport cells within the machine. The mini accepts tubes only for inputting cells or beads. The Guava_EasyCyte_Mini cytometer is a small portable cytometer particularly useful for field measurement.",http://www.guavatechnologies.com/main/products/easyCyteMini.cfm,,,,,,Guava EasyCyte Mini,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0400048,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Guava EasyCyte Mini,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,John Quinn,,
http://purl.obolibrary.org/obo/OBI_0000835,manufacturer,,A person or organization that has a manufacturer role,false,,,http://purl.obolibrary.org/obo/BFO_0000040,,,,,,,,,,,,,,,,,,,A person or organization that has a manufacturer role,,,,,,,manufacturer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000123,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000835,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,manufacturer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0600008,acquisition,,the planned process of gaining possession of a continuant ,false,,,http://purl.obolibrary.org/obo/OBI_0001928,,,,,,,,,,,,,,,,,This needs to be fleshed out and logical definitions added that will allow to place the children terms automatically under acquisition,,the planned process of gaining possession of a continuant ,IEDB,,,,,"Following OBI call November 2012,5th:
addition of a restriction to acquisition class to capture the need of having selection criteria
Relates to the creation of a class 'selection rule'|5/31/2012 - OBI workshop: This process is not implying ownership of the material / information. ",acquisition,,Downloading a 3D structure from the PDB. Purchasing antibodies from sigma. ,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000122,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0600008,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,acquisition,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Bjoern Peters,,
http://purl.obolibrary.org/obo/OBI_0000719,vaccine preparation,,vaccine preparation is a planned  process with specified output a vaccine,false,,,http://purl.obolibrary.org/obo/OBI_0000094,,http://purl.obolibrary.org/obo/OBI_0000456,,,,,,,,,,,,,,,,,vaccine preparation is a planned  process with specified output a vaccine,OBI,,,,,,vaccine preparation,,The production of B. pertussis vaccine.,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000719,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,vaccine preparation,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/PR_000006592,deoxyribonuclease-1,,A protein that is a translation product of the human DNASE1 gene or a 1:1 ortholog thereof.,false,,,http://purl.obolibrary.org/obo/PR_000000001,,,,,,,,,,,,,,,,,,,A protein that is a translation product of the human DNASE1 gene or a 1:1 ortholog thereof.,,,,,,,deoxyribonuclease-1,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PR:000006592,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/pr.owl,,,,,,,,,,,,,,,,,,,deoxyribonuclease-1,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001350,detection of specific nucleic acids with complementary probes assay measuring epitope specific interferon-gamma production by T cells,IFNg release|RNA/DNA detection,An assay of epitope specific interferon-gamma production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001414,,,,,,,,,,,,,,,,,,,An assay of epitope specific interferon-gamma production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interferon-gamma production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001350,,,,,,,,,,,,,,,,,,,,,,,,IFNg release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interferon-gamma production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
http://purl.obolibrary.org/obo/OBI_0001329,family history design,,"A study design in which the family history such as traits, characteristics, susceptibility to disease is studied.",false,,,http://purl.obolibrary.org/obo/OBI_0500000,,,,,,,,,,,,,,,,,,,"A study design in which the family history such as traits, characteristics, susceptibility to disease is studied.",MO_544 family_history_design,,,,,,family history design,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000268,,,,,,,,,,,,,,,,OBI:0001329,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,family history design,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"Person: Chris Stoeckert, Jie Zheng",,
http://purl.obolibrary.org/obo/CL_0000235,macrophage,,"A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells.",false,,,http://purl.obolibrary.org/obo/CL_0000000,,,,,,,,,,,,,,,,,,,"A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells.",,,,,,,macrophage,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CL:0000235,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/cl.owl,,,,,,,,,,,,,,,,,,,macrophage,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/CL_0000232,erythrocyte,,"A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen.",false,,,http://purl.obolibrary.org/obo/CL_0000000,,,,,,,,,,,,,,,,,,,"A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen.",,,,,,,erythrocyte,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CL:0000232,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/cl.owl,,,,,,,,,,,,,,,,,,,erythrocyte,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/CL_0000236,B cell,,"A lymphocyte of B lineage with the phenotype CD19-positive, CD20-positive, and capable of B cell mediated immunity.",false,,,http://purl.obolibrary.org/obo/CL_0000542,,,,,,,,,,,,,,,,,,,"A lymphocyte of B lineage with the phenotype CD19-positive, CD20-positive, and capable of B cell mediated immunity.",,,,,,,B cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CL:0000236,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/cl.owl,,,,,,,,,,,,,,,,,,,B cell,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/UO_0000095,volume unit,,"A unit which is a standard measure of the amount of space occupied by any substance, whether solid, liquid, or gas.",false,,,http://purl.obolibrary.org/obo/IAO_0000003,,,,,,,,,,,,,,,,,,,"A unit which is a standard measure of the amount of space occupied by any substance, whether solid, liquid, or gas.",,,,,,,volume unit,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,UO:0000095,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/uo.owl,,,,,,,,,,,,,,,,,,,volume unit,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/GO_0002390,platelet activating factor production,,"The synthesis or release of platelet activating factor following a stimulus, resulting in an increase in its intracellular or extracellular levels.",false,,,http://purl.obolibrary.org/obo/GO_0001816,,,,,,,,,,,,,,,,,,,"The synthesis or release of platelet activating factor following a stimulus, resulting in an increase in its intracellular or extracellular levels.",,,,,,,platelet activating factor production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,GO:0002390,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/go.owl,,,,,,,,,,,,,,,,,,,platelet activating factor production,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
http://purl.obolibrary.org/obo/OBI_0001001,Edinburgh handedness assay,,"The Edinburgh Handedness assay is an assay in which a set of questions  = the Edinburgh Handedness inventory - is asked and the answers to these questions are turned into a score, used to assess the dominance of a person's right or left hand in everyday activities. The inventory can be used by an observer assessing the person, or by a person self-reporting hand use. The latter method tends to be less reliable due to a person over-attributing tasks to the dominant hand.",false,,,http://purl.obolibrary.org/obo/OBI_0000944,,,,,,,,,,,,,,,,,,,"The Edinburgh Handedness assay is an assay in which a set of questions  = the Edinburgh Handedness inventory - is asked and the answers to these questions are turned into a score, used to assess the dominance of a person's right or left hand in everyday activities. The inventory can be used by an observer assessing the person, or by a person self-reporting hand use. The latter method tends to be less reliable due to a person over-attributing tasks to the dominant hand.",WEB:http://en.wikipedia.org/wiki/Edinburgh_Handedness_Inventory,,,,,,Edinburgh handedness assay,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/OBI_0000991,,,OBI:0001001,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Edinburgh handedness assay,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Person:Alan Ruttenberg|PERSON:Jessica Turner,,
http://purl.obolibrary.org/obo/OBI_1110057,MHC:epitope complex binding to TCR,,a process of an MHC molecule binding to an entity playing the role of epitope to create an MHC:epitope complex which is then bound by a TCR molecule.,false,,,http://purl.obolibrary.org/obo/OBI_1110014|http://purl.obolibrary.org/obo/OBI_0001588,,,,,,,,,,,,,,,,,,,a process of an MHC molecule binding to an entity playing the role of epitope to create an MHC:epitope complex which is then bound by a TCR molecule.,IEDB,,,,,,MHC:epitope complex binding to TCR,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:1110057,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,MHC:epitope complex binding to TCR,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,IEDB,,
http://purl.obolibrary.org/obo/OBI_0000580,AVANCE II spectrometer,,"A spectrometer suitable for metabolomics and in vivo NMR studies but structural analysis of small molecules and low molecular weight proteins can also be performed. To accomplish these studies there are six probe-heads available. A successor, the AVANCE III came out recently.",false,,,http://purl.obolibrary.org/obo/OBI_0000596,,,,,,,,,,,,,,,,,NMR instrument,,"A spectrometer suitable for metabolomics and in vivo NMR studies but structural analysis of small molecules and low molecular weight proteins can also be performed. To accomplish these studies there are six probe-heads available. A successor, the AVANCE III came out recently.",WEB:<http://cermax.itqb.unl.pt/mambo/en/index.php?option=com_content&task=view&id=36&Itemid=93>|http://msi-ontology.sourceforge.net/ontology/NMR.owl#msi_400197,,,,,,AVANCE II spectrometer,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0000580,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,AVANCE II spectrometer,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,PERSON:Daniel Schober,,
http://purl.obolibrary.org/obo/OBI_0001382,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-27 production by T cells,IL-27 release|RNA/DNA detection,An assay of epitope specific interleukin-27 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,false,,,http://purl.obolibrary.org/obo/OBI_0001198,,,,,,,,,,,,,,,,,,,An assay of epitope specific interleukin-27 production by T cells that uses a detection of specific nucleic acids with complementary probes assay.,IEDB,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-27 production by T cells,,,,,,,,,,,,,,,http://purl.obolibrary.org/obo/IAO_0000120,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,OBI:0001382,,,,,,,,,,,,,,,,,,,,,,,,IL-27 release|RNA/DNA detection,,,,,,,,,,,,,,,,,,,,,,detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-27 production by T cells,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,"PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters",,
