EpilepsyOntology.owl
type: Ontology
comment: The Epilepsy Ontology (BioPortal ID: EpSO) is an application ontology developed to support epilepsy research, patient care, and health system management. The updated version of the Epilepsy Ontology adds Dravet Syndrome (DS) related terms covering both model systems and patients with DS. This version is an extension of the previous version of the ontology that focused on neuropathology terms, including immunohistochemistry, microscopy, and anatomical description, related to epilepsy. This work has been funded in part by the Dravet Syndrome Foundation, International League Against Epilepsy (ILAE), and the US National Institutes of Health. Some of the funding agencies retain intellectual ownership of the ontology, together with the Case Western Reserve University and other collaborating institutions. Contributors: Satya S. Sahoo, Jeffrey Buchhalter, Samden D. Lhatoo, Katja Kobow, Deepak K. Gupta, Alireza Bozorgi, Aman Dabir, Bilal Gonen, Hans O. Luders, Kenneth Loparo, Veronica Hood Contact: satya.sahoo@case.edu
comment: The Epilepsy Ontology is released under the Creative Commons Non-Commercial, Share Alike and Unported License.
comment: Version date: March, 2024
version info: 3

hasVariantConsequence
type: ObjectProperty

WHO grading
type: ObjectProperty

isProvokedBy
type: ObjectProperty

acetyl-CoA acetyltransferase 1
type: Class
subclass of: Gene

acrosin
type: Class
subclass of: Gene

adhesion G protein-coupled receptor V1
type: Class
subclass of: Gene

aldehyde dehydrogenase 7 family member A1
type: Class
subclass of: Gene

alkaline phosphatase, biomineralization associated
type: Class
subclass of: Gene

arylsulfatase A
type: Class
subclass of: Gene

aristaless related homeobox
type: Class
subclass of: Gene

N-acylsphingosine amidohydrolase 1
type: Class
subclass of: Gene

atrophin 1
type: Class
subclass of: Gene

ATPase Na+/K+ transporting subunit alpha 2
type: Class
subclass of: Gene

ATPase Na+/K+ transporting subunit alpha 3
type: Class
subclass of: Gene

Right Fronto Parietal Abcess
type: Class
subclass of: Structural Cause

Abdominal Aura
type: Class
subclass of: Non-Specific Aura
comment: Abdominal aura is used to denote a type of somatosensory or somaesthetic aura that typically manifests itself as a rising epigastric sensation.
comment: Autonomic (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Abdominal Aura Status
type: Class
subclass of: Aura status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Abilify
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 352393

Abnormal Developmental Status
type: Class
subclass of: Developmental Status

Abnormal EEG Pattern
type: Class
subclass of: EEG Pattern
label: Abnormal Electroencephalogram Pattern
label: AbnormalEEGPattern

Abnormal Neurological Exam Finding
type: Class
subclass of: Neurological Exam Finding
comment: Abnormal

Abnormal Radial Migration
type: Class
subclass of: CorticalDyslamination

Abnormal tangential cortical lamination
type: Class
subclass of: CorticalDyslamination

Acephalobrachius (disorder)
type: Class
subclass of: Congenital anomaly of head (disorder)

AChR
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: Neurotransmitter receptor
label: Acetylcholin Receptor

AChRA Associated Encephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
subclass of: Restriction
  on property: hasAssociatedAntigen
  some values from: AChR
label: AChRAssociatedEncephalitis
label: Acetylcholin Receptor Associated Encephalitis

Acetylcholine chloride
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: Neuro Transmitter

Acquired Epileptic Aphasia
type: Class
subclass of: Undetermined Epilepsy
label: Landau-Kleffner syndrome

Acquired periventricular cyst
type: Class
subclass of: Cerebral cyst (disorder)
label: Acquired periventricular cyst (disorder)

Activation Procedure
type: Class
subclass of: Normal EEG Pattern

Activity of Arousal
type: Class
subclass of: Sleep Related EEG Pattern
comment: EEG pattern occuring during awakening from sleep and usually consists of widespread, usually alpha frequency rhythms

Activity of Drowsiness
type: Class
subclass of: Sleep Related EEG Pattern
comment: EEG pattern occuring during the onset of sleep (becoming drwosy) and consists of -

Activity of Sleep
type: Class
subclass of: Sleep Related EEG Pattern
comment: EEG pattern occuring during sleep

Acute Dissociated Cell Culture
type: Class
subclass of: Disassociated Cell Culture
label: Acute Dissociated Culture
label: AcuteDissociatedCulture

Adderall
type: Class
subclass of: Drug Brand Name
see also: RxCUI 84815

Adgan
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 215027

Adhesion Molecule
type: Class
subclass of: Protein Function
comment: https://www.nature.com/articles/pr199633
label: Cell adhesion molecule

Adolescent
type: Class
subclass of: Human
subclass of: Restriction
  on property: hasRecordedAge
  min qualified cardinality: 13
  on class: Year
subclass of: Restriction
  on property: hasRecordedAge
  max qualified cardinality: 18
  on class: Year
comment: the period between puberty and the completion of physical growth, roughly from 11 to 19 years of age

Adult
type: Class
subclass of: Human
subclass of: Restriction
  on property: hasRecordedAge
  min qualified cardinality: 19
  on class: Year
comment: having attained full growth or maturity, or an organism that has done so.

Adult Zebrafish
type: Class
subclass of: Zebrafish

ASPS
type: Class
subclass of: Sleep disorder
label: Advanced Sleep Phase Syndrome

Age
type: Class
subclass of: Organism Phenotype
comment: The length of time that one has existed; duration of life

Akinectic Status
type: Class
subclass of: Special Status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Ictal paresis (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Akinetic Episode
type: Class
subclass of: Special Episode

Akinetic Seizure
type: Class
subclass of: Special Seizure
comment: Akinetic seizures are characterized by inability to perform voluntary movements and preferentially affect more distal muscles.
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Generalized Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Motor (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Alcohol Abuse
type: Class
subclass of: Substance Abuse

Alkabel
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 608686

Alpha Amino 3 Hydroxy 5 Methyl 4 Isoxazolepropionic Acid Receptor
type: Class
subclass of: Ionotropic Glutamate Receptor

AMPAR1
type: Class
subclass of: Restriction
  on property: hasFunction
  some values from: Neurotransmitter receptor

AMPAR1 Associated Encephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
subclass of: Restriction
  on property: hasAssociatedAntigen
label: AMPAR1AssociatedEncephalitis
label: Alpha Amino 3 Hydroxy 5 Methyl 4 Isoxazolepropionic Acid Receptor 1 Associated Encephalitis

AMPAR2
type: Class
subclass of: Restriction
  on property: hasFunction
  some values from: Neurotransmitter receptor

AMPAR2 Associated Encephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
subclass of: Restriction
  on property: hasAssociatedAntigen
label: AMPAR2AssociatedEncephalitis
label: Alpha Amino 3 Hydroxy 5 Methyl 4 Isoxazolepropionic Acid Receptor 2 Associated Encephalitis

Alpha Coma
type: Class
subclass of: Special Pattern
comment: Alpha coma / Alpha stupor (AS) refers to EEG of a comatose/stuporous patient in which alpha activity predominates.

Alpha Rhythm
type: Class
subclass of: Normal EEG Pattern
comment: Alpha rhythm is the initial starting point for visual analysis of EEG, originates from occipital region of brain and has a frequency of 8 to 13 Hertz in adults.

Alpha Stupor
type: Class
subclass of: Special Pattern
comment: Alpha coma / Alpha stupor (AS) refers to EEG of a comatose/stuporous patient in which alpha activity predominates.

Alpha Variant
type: Class
subclass of: Rhythmic Benign Variant
comment: Alpha variant consists of activity over the posterior head regions that have a harmonic relationship to the alpha rhythm and show similar activity and distribution.

Altered Level Of Consciousness
type: Class
subclass of: Seizure consciousness state
comment: Altered Level Of Consciousness refers to relative unresponsiveness with postictal amnesia for the events that happened during the seizure.

Amaurosis Status
type: Class
subclass of: Visual Aura Status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Amisulpride
type: Class
subclass of: Drug Ingredient
comment: Antidepressant Drug
see also: RxCUI 46303

Amitriptyline
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Class
    intersection of: Amitriptyline Hydrochloride
    intersection of: Amitriptyline Oxide
    intersection of: Amitriptyline Pamoate
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Elavil
    union of: Etrafon
    union of: Limbitrol
    union of: Vanatrip
comment: Neuroleptic Drug
see also: RxCUI 704

Amitriptyline Hydrochloride
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 203168

Amitriptyline Oxide
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 236734

Amitriptyline Pamoate
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 235737

Amnestic Seizure
type: Class
subclass of: Special Seizure
comment: Cognitive (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Nonmotor Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Unknown Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Amoxapine
type: Class
subclass of: Drug Ingredient
comment: Neuroleptic Drug
see also: RxCUI 722

Amphetamine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Class
    intersection of: Amphetamine Aspartate
    intersection of: Amphetamine Aspartate Monohydrate
    intersection of: Amphetamine Saccharate
    intersection of: Amphetamine Sulfate
subclass of: Restriction
  on property: hasTradename
  some values from: Adderall
comment: Neuroleptic Drug
see also: RxCUI 725

Amphetamine Aspartate
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 221057

Amphetamine Aspartate Monohydrate
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 405812

Amphetamine Saccharate
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 540810

Amphetamine Sulfate
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 81952

AMPH
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: Endocytosis
label: amphiphysin I

AMPH Associated Encephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
subclass of: Restriction
  on property: hasAssociatedAntigen
  some values from: AMPH
label: AMPHAssociatedEncephalitis
label: Amphiphysin Associated Encephalitis

Amygdalar
type: Class
subclass of: Basal Ganglion of Telencephalon
comment: Subdivision of basal ganglion of telencephalon which is an almond-shaped gray mass in the dorsomedial part of the temporal lobe. (source: FMA)

Amygdalar Epilepsy
type: Class
subclass of: Temporal Lobe Epilepsy
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: Psychic Aura

Amygdaloclaustral Area
type: Class
subclass of: Telencephalon Zone

Amygdalohippocampal Area
type: Class
subclass of: Telencephalon Zone

Amygdalopiriform Transition Area
type: Class
subclass of: Telencephalon Zone

Amyloid Angiopath Spontaneous Intracerebral Hemorrhage
type: Class
subclass of: Intracerebral Hemorrhage

Anafranil
type: Class
subclass of: Drug Brand Name
comment: RxCUI 756
comment: http://purl.bioontology.org/ontology/RXNORM/756

AA
type: Class
subclass of: Astrocytic
label: Anaplastic Astrocytoma

Anaplastic Ependymoma
type: Class
subclass of: Ependymal Tumor
subclass of: Restriction
  on property: WHO grading
  some values from: WHO_III

Anaplastic Ganglioglioma
type: Class
subclass of: Brain Glial Neuronal Tumor
subclass of: Restriction
  on property: WHO grading
  some values from: WHO_III

Anaplastic Glioma
type: Class
subclass of: Glioma

Anaplastic Oligoastrocytoma
type: Class
subclass of: Mixed Astrocytic Oligodendroglial
subclass of: Restriction
  on property: WHO grading
  some values from: WHO_III

Anaplastic Oligodendroglioma
type: Class
subclass of: Oligodendroglial
subclass of: Restriction
  on property: WHO grading
  some values from: WHO_III

Anaplastic Pleomorphic Xanthoastrocytoma
type: Class
subclass of: Other Astrocytic Tumor
subclass of: Restriction
  on property: hasAssociatedMutationIn
  some values from: B-Raf proto-oncogene
subclass of: Restriction
  on property: WHO grading
  some values from: WHO_III
comment: Associated with frequent BRAF V600E mutation

Anatomical Boundary Entity
type: Class
subclass of: Immaterial Anatomical Entity
comment: "Immaterial anatomical entity of one less dimension than the anatomical entity it bounds or demarcates from another anatomical entity. Examples: surface of heart, surface of epithelial cell, cervicothoracic plane, supra-orbital notch, costal margin, apex beat, Sylvian point." (Foundational Model of Anatomy)

Anatomical Cavity
type: Class
subclass of: Anatomical Space
comment: "Anatomical space which contains portions of one or more body substances and is bounded by the internal surface of one maximally connected anatomical structure or two or more adjacent anatomical structures. Examples: nasal cavity, cavity of stomach, pharyngeal recess space, lumen of artery, cavity of serous sac." (Foundational Model of Anatomy)

Anatomical Cluster
type: Class
subclass of: Anatomical Structure
comment: Anatomical group that has its parts adjacent to one another. Anatomical structure, which has as its parts a heterogeneous collection of organs, organ parts, cells or body part subdivisions that are adjacent to, or continuous with one another; does not constitute an organ, organ system or organ system subdivision, or body part or body part subdivision.

Anatomical Compartment Space
type: Class
subclass of: Anatomical Space
comment: "Anatomical space which contains two or more anatomical structures demarcated by bona fide boundaries and is bounded by the surface of one or more anatomical structures. Examples: orbital cavity, suprasternal space, thoracic cavity, fascial space, hepatic lacuna." (Foundational Model of Anatomy)

Anatomical Conduit Space
type: Class
subclass of: Anatomical Space
comment: "Anatomical space which connects two or more compartment spaces or two or more anatomical cavities. Examples: foramen magnum, pyloric orifice, space of right inguinal canal, nutrient canal space" (Foundational Model of Anatomy)

Anatomical containment
type: Class
subclass of: Non-physical anatomical entity

Anatomical Coordinate
type: Class
subclass of: Non-physical anatomical entity

Anatomical entity
type: Class
subclass of: Bodily Feature

Anatomical Fissure
type: Class
subclass of: Anatomical Space
label: Groove

Anatomical Line
type: Class
subclass of: Anatomical Boundary Entity
comment: "Anatomical boundary entity, each instance of which has one spatial dimension. Examples: margin of tongue, posterior border of right lung, inferior margin of liver, arcuate line of hip bone, sulcus terminalis of heart, pancreatic incisure." (Foundational Model of Anatomy)

Anatomical Point
type: Class
subclass of: Anatomical Boundary Entity
comment: "Anatomical boundary entity, each instance of which has zero spatial dimension. Examples: Apex of lung, vertex, mentale, McBurney's point." (Foundational Model of Anatomy)

Anatomical Point of Face
type: Class
subclass of: Anatomical Point of Head

Anatomical Point of Head
type: Class
subclass of: Anatomical Point

Anatomical Point of Skull
type: Class
subclass of: Anatomical Point of Head
label: Anatomical cranial point
label: Cranial osteometric point

Anatomical Space
type: Class
subclass of: Immaterial Anatomical Entity
comment: "Immaterial anatomical entity, each instance of which has three spatial dimensions. Examples: body cavity, thoracic cavity, lesser sac, cavity of right atrium, lumen of aorta, mediastinal space, space of anterior compartment of forearm." (Foundational Model of Anatomy)

Anatomical Structure
type: Class
subclass of: Material Anatomical Entity
comment: Anatomical structure, which has as its parts a heterogeneous collection of organs, organ parts, cells, cell parts or body part subdivisions that are adjacent to, or continuous with one another; does not constitute a cell part, cell, tissue, organ, organ system or organ system subdivision, cardinal body part, body part subdivision or anatomical junction. Examples: joint, adnexa of uterus, root of lung, renal pedicle, back. (source: FMA)

Anatomical Surface
type: Class
subclass of: Anatomical Boundary Entity
comment: "Anatomical boundary entity, each instance of which has two spatial dimensions. Examples: body surface, epigastrium, precordium, right iliac fossa." (Foundational Model of Anatomy)

Anergan
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 992861

AG
type: Class
subclass of: Other Glioma
subclass of: Restriction
  on property: hasAssociatedMutationIn
  some values from: MYB proto-oncogene, transcription factor
subclass of: Restriction
  on property: WHO grading
  some values from: WHO grade I
synonym: Angiocentric glioma (morphologic abnormality)
label: Angiocentric Glioma

Animal Seizure-like Activity
type: Class
subclass of: Paroxysmal Event

Anterior Cingulate Epilepsy
type: Class
subclass of: Cingulate Epilepsy
subclass of: Restriction
  on property: hasInterIctalEpileptiformAbnormality
  some values from: Class
    union of: Sharp Wave
    union of: Spike
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: Class
    union of: Hypermotor Seizure
    union of: Psychic Aura
    union of: Simple Motor Seizure
subclass of: Restriction
  on property: hasAgeOfOnset
  min qualified cardinality: 2
  on class: Year
subclass of: Restriction
  on property: hasAgeOfOnset
  max qualified cardinality: 51
  on class: Year

Anterior Cranial Fossa
type: Class
subclass of: Cranial Fossa

AnteriorHypothalamicRegion
type: Class
subclass of: Hypothalamus Zone
comment: Anterior Hypothalamic Region

Anterior Median Eminence
type: Class
subclass of: Diencephalon Zone

Anterior Slow Activity in Children
type: Class
subclass of: Normal EEG Pattern
comment: Slow wave activity, usually in the 4-7 Hz range seen in the anterior head regions in children.

Anterior transverse temporal convolution of Heschl
type: Class
subclass of: TemporalLobeGyrus
label: Anterior transverse temporal gyrus
label: First transverse gyrus of Heschl
label: Great transverse gyrus of Heschl

Anti Neuronal Nuclear Antibody 1 Associated Encephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
subclass of: Restriction
  on property: hasAssociatedAntigen
  some values from: ANNA1Antibody
comment: Anti-Hu associated encephalitis
label: Anti-ANNA1 Associated Encephalitis
label: Anti-ANNA1AssociatedEncephalitis

ANNA2AssociatedEncephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
subclass of: Restriction
  on property: hasAssociatedAntigen
  some values from: ANNA2Antibody
label: Anti Neuronal Nuclear Antibody 2 Associated Encephalitis

ANNA3AssociatedEncephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
subclass of: Restriction
  on property: hasAssociatedAntigen
  some values from: ANNA3
label: Anti Neuronal Nuclear Antibody 3 Associated Encephalitis

Antibody-associated Encelphalitis
type: Class
subclass of: Encephalitis
label: Autoimmune encelphalitis

Antinaus
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 992865

Aphasic Episode
type: Class
subclass of: Special Episode

Aphasic Seizure
type: Class
subclass of: Special Seizure
comment: Aphasic seizures are seizures during which the patient has either a global aphasia or a more selective expressive or comprehensive aphasia.
comment: Cognitive (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Nonmotor Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Unknown Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Aphasic Status
type: Class
subclass of: Special Status
label: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Aplenzin
type: Class
subclass of: Drug Brand Name
see also: RxCUI 835486

Apoptosis (morphologic abnormality)
type: Class
subclass of: Morphologic alteration

Apraxis Seizure
type: Class
subclass of: Special Seizure
comment: Cognitive (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Nonmotor Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Unknown Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Aptiom
type: Class
subclass of: Drug Brand Name
see also: RxCUI 1482508

AQP4
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: Channel

AQP4AssociatedEncephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
subclass of: Restriction
  on property: hasAssociatedAntigen
  some values from: AQP4
label: Aquaporin 4 Associated Encephalitis

Aripiprazole
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Abilify
comment: Neuroleptic Drug
see also: RxCUI 89013

Arm
type: Class
subclass of: Proximal Free Limb Segment
comment: The part of the forelimb extending from the shoulder to the autopod[cjm]

ArteriovenousMalformation
type: Class
subclass of: Vascular Malformation
comment: Arteriovenous Malformation (AVM)

Artifact Obscured EEG (AOE)
type: Class
subclass of: Inter Ictal Pattern
comment: Artifact-obscured EEG (AOE) refers to an ictal record that is obscured by artifacts, thereby making its interpretation difficult or impossible.

Asenapine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Asenapine Maleate
subclass of: Restriction
  on property: hasTradename
  some values from: Saphris
comment: Antidepressant Drug
see also: RxCUI 784649

Asenapine Maleate
type: Class
subclass of: Precise Drug Ingredient
synonym: RxCUI 860647

Astatic Episode
type: Class
subclass of: Special Episode

Astatic Seizure
type: Class
subclass of: Special Seizure
comment: Astatic seizures are characterized by an epileptic fall, but the precise mechanism of the fall cannot be defined by the available information.
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Generalized Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Motor (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Astatic Status
type: Class
subclass of: Special Status
label: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
label: Ictal paresis (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
label: Motor onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Astrocytus
type: Class
subclass of: Macroglial cell
subclass of: Restriction
  on property: isMarkedBy
  some values from: GFAP
label: astrocytic glia

Asymmetry Pattern
type: Class
subclass of: Special Pattern
comment: Asymmetry (AS) refers exclusively to amplitude differences of physiological EEG activity between the two hemispheres.

CardiacArrest
type: Class
subclass of: ECG label

Ativan
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 202479

Atomoxetine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Atomoxetine Hydrochloride
subclass of: Restriction
  on property: hasTradename
  some values from: Strattera
comment: Neuroleptic Drug
see also: RxCUI 38400

Atomoxetine Hydrochloride
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 353103

Atonic
type: Class
subclass of: Special Episode
label: Atonic Episode

Atonic Seizure
type: Class
subclass of: Special Seizure
comment: Atonic seizures are characterized by loss of postural tone.
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Generalized Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Motor (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Atonic Status
type: Class
subclass of: Special Status
comment: Ictal paresis (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
label: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
label: Motor onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Atrial Fibrillation
type: Class
subclass of: Arrhythmia

Atrial Myocyte
type: Class
subclass of: Heart Myocyte

Atrophic degeneration (morphologic abnormality)
type: Class
subclass of: Degenerative abnormality (morphologic abnormality)

Atrophy (morphologic abnormality)
type: Class
subclass of: Degenerative abnormality (morphologic abnormality)
label: http://purl.bioontology.org/ontology/SNOMEDCT/13331008

ADHD
type: Class
subclass of: Neuropsychiatric Problem
label: Attention deficit hyperactivity disorder

Attention deficit hyperactivity disorder combined type
type: Class
subclass of: ADHD
label: Attention deficit hyperactivity disorder, combined type

Attention deficit hyperactivity disorder, inattentive presentation (restrictive)
type: Class
subclass of: ADHD

Attention deficit hyperactivity disorder, predominantly hyperactive impulsive type
type: Class
subclass of: ADHD

Attention deficit hyperactivity disorder, predominantly inattentive type
type: Class
subclass of: ADHD

Atypical Dialeptic Episode
type: Class
subclass of: Dialeptic Episode

Atypical Dialeptic Seizure
type: Class
subclass of: Dialeptic Seizure

Atypical Dialeptic Status
type: Class
subclass of: Dialeptic Status
comment: Atypical (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Generalized Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Versio
comment: Impaired Consciousness (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Atypical Ganglioglioma
type: Class
subclass of: Brain Glial Neuronal Tumor
subclass of: Restriction
  on property: WHO grading
  some values from: Class
    union of: WHO_II
    union of: WHO_III

Auditory Aura
type: Class
subclass of: Non-Specific Aura
comment: Auditory auras consist of auditory hallucinations in the the form of sounds or noises that may or may not be localized in space.
comment: Sensory (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Auditory Aura Status
type: Class
subclass of: Aura status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Auditory Frontocentral N400
type: Class
subclass of: Scalp Recorded ERP Extracted Pattern

Auditory Frontocentral P200
type: Class
subclass of: Scalp Recorded ERP Extracted Pattern
label: auditory_frontocentral_P200

Auditory N2b
type: Class
subclass of: Scalp Recorded ERP Extracted Pattern

Auditory stimulus
type: Class
subclass of: Inducing Factor

Non-Specific Aura
type: Class
subclass of: Epileptic Seizure
comment: An aura is the perceptual disturbance experienced by epileptic patient and not detectable by an observer.
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Nonmotor Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Unclassified (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Unknown Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Aura status
type: Class
subclass of: SE
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Autism Spectrum Disorder
type: Class
subclass of: General Learning Disability

Automatism with Preserved Responsiveness
type: Class
subclass of: Automatism

Automatism without Preserved Responsiveness
type: Class
subclass of: Automatism

Automotor Episode
type: Class
subclass of: Complex Motor Episode

Automotor Seizure
type: Class
subclass of: Complex Motor Seizure
comment: Automotor seizures are complex motor seizures characterized primarily by automatisms of the distal segments of body, including in particular the fingers, hands, tongue and lips.

Automotor Status
type: Class
subclass of: Complex Motor Status

Autonomic Aura
type: Class
subclass of: Non-Specific Aura
comment: A term used to denote a type of *aura that manifests itself as an autonomic alteration such as palpitations or 'hot flashes', without any objective proof of an autonomic disturbance.
comment: Autonomic (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Autonomic Aura Status
type: Class
subclass of: Aura status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Autonomic Dysfunction
type: Class
subclass of: Aetiology

Autonomic Episode
type: Class
subclass of: Non-Epileptic Seizure

Autonomic Seizure
type: Class
subclass of: Epileptic Seizure
comment: Autonomic (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Autonomic seizures are epileptic seizures which have objectively documented autonomic signs as main ictal symptoms.

Autonomic Status
type: Class
subclass of: SE
comment: Autonomics status epilepticus (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Generalized Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Unknown Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

ADNFLE
type: Class
subclass of: Single Focal Epilepsy
subclass of: Restriction
  on property: hasAgeOfOnset
  some values from: Child
subclass of: Restriction
  on property: hasAssociatedDisorder
  some values from: General Learning Disability
subclass of: Restriction
  on property: hasAssociatedMutationIn
  some values from: Class
    union of: cholinergic receptor, nicotinic, alpha 2 (neuronal)
    union of: cholinergic receptor, nicotinic, alpha 4 (neuronal)
    union of: cholinergic receptor, nicotinic, beta 2 (neuronal)
subclass of: Restriction
  on property: hasEtiology
  some values from: Genetic Mutation
subclass of: Restriction
  on property: hasIctalEpileptiformAbnormality
  some values from: EEG-SZ
subclass of: Restriction
  on property: hasInterIctalEpileptiformAbnormality
  some values from: Class
    union of: PolySpikes
    union of: Sharp Wave
    union of: Spike
subclass of: Restriction
  on property: hasPreferredMedication
  some values from: Zonisamide
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: Hypermotor Seizure
label: Autosomal Dominant Nocturnal Frontal Lobe Epilepsy

ADPEAF
type: Class
subclass of: Single Focal Epilepsy
subclass of: Restriction
  on property: hasAssociatedMutationIn
  some values from: leucine-rich, glioma inactivated 1
subclass of: Restriction
  on property: hasEtiology
  some values from: Genetic Mutation
subclass of: Restriction
  on property: hasIctalEpileptiformAbnormality
  some values from: EEG-SZ
subclass of: Restriction
  on property: hasInterIctalEpileptiformAbnormality
  some values from: Class
    union of: Sharp Wave
    union of: Spike
subclass of: Restriction
  on property: hasPreferredMedication
  some values from: Class
    union of: Phenytoin
    union of: Valproate
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: Class
    union of: Aphasic Seizure
    union of: Auditory Aura
subclass of: Restriction
  on property: hasAgeOfOnset
  min qualified cardinality: 4
  on class: Year
subclass of: Restriction
  on property: hasAgeOfOnset
  max qualified cardinality: 50
  on class: Year
label: Autosomal Dominant Partial Epilepsy With Auditory Features

Averaged EEG Data
type: Class
subclass of: EEG data

B Cell
type: Class
subclass of: Lymphocyte
label: B Lymphocyte
label: lymphocyte of B lineage

B-Raf proto-oncogene
type: Class
subclass of: Gene

Background Slow
type: Class
subclass of: Slow Activity
comment: Continuous slow (CS) refers to the activity that occurs continuously (>80% of the time), is non-responsive to external stimuli, and clearly exceeds the amount considered physiologically normal for the patient's age.
label: Background Slow Activity

Background Suppression
type: Class
subclass of: Special Pattern
comment: Background suppression (BS) refers to activity which is less than 10 uV (reference derivation).

Balloon Cell
type: Class
subclass of: Radial glial fiber
subclass of: Restriction
  on property: isMarkedBy
  some values from: Class
    union of: pS6
    union of: Vimentin
comment: Reference: Balloon cells derive from radial glial progenitor cells (https://academic.oup.com/brain/article/130/9/2267/291780)

Band Heterotopia
type: Class
subclass of: Heterotopia

Banzel
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 824296
comment: Treats seizures in patients who have Lennox-Gastaut syndrome (LGS).

Basal Temporal Epilepsy
type: Class
subclass of: Temporal Lobe Epilepsy

Basal Temporal
type: Class
subclass of: TemporalLobeSegment

Mature Basophil
type: Class
subclass of: Granular Leukocyte

Behavioral Arrest
type: Class
subclass of: No Clinical Signs

Bellatal
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 215608

Benign Childhood Epilepsy With Centrotemporal Spikes
type: Class
subclass of: Single Focal Epilepsy
subclass of: Restriction
  on property: hasEtiology
  some values from: Genetic Defect
subclass of: Restriction
  on property: hasInterIctalEpileptiformAbnormality
  some values from: Benign Focal Epileptiform Discharge of Childhood (BFEDC)
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: Class
    union of: Clonic Seizure
    union of: Somatosensory Aura
    union of: ConvulsiveMotorSeizure
subclass of: Restriction
  on property: hasAgeOfOnset
  min qualified cardinality: 4
  on class: Year
subclass of: Restriction
  on property: hasAgeOfOnset
  max qualified cardinality: 10
  on class: Year

Benign EEG Pattern
type: Class
subclass of: EEG Pattern
label: Benign Electroencephalogram Pattern

Benign Focal Epileptiform Discharge of Childhood (BFEDC)
type: Class
subclass of: Inter Ictal Pattern
comment: Benign focal epileptiform discharges of childhood (BFEDC) refer to regional or multiregional sharp waves that are normally followed by a negative slow wave with lower amplitude than the negative peak of the sharp wave and ocassionally show a dipolar distribution.

Benign Myoclonic Epilepsy In Infancy
type: Class
subclass of: Generalized Epilepsy

Benign Neonatal Convulsions
type: Class
subclass of: Generalized Epilepsy

Benign Neonatal Familial Convulsions
type: Class
subclass of: Generalized Epilepsy

Beta Activity
type: Class
subclass of: Normal EEG Pattern
comment: Beta activity refers to activity with frequency range 13 to 30 Hz.

Beta Coma
type: Class
subclass of: Special Pattern
comment: Beta coma (BC) / Beta stupor (BS) refers to predominance of beta activity with amplitudes higher than 30 uV in a comatose/stuporous patient.

Beta Stupor
type: Class
subclass of: Special Pattern
comment: Beta coma (BC) / Beta stupor (BS) refers to predominance of beta activity with amplitudes higher than 30 uV in a comatose/stuporous patient.

Bilateral Periodic Lateralized Epileptiform Discharge (Bi-PLED)
type: Class
subclass of: Periodic Lateralized Epileptiform Discharge (PLED)
comment: Periodic sharp waves that occur in both hemispheres but do so asynchronously between the two hemispheres

BiLobar Epilepsy
type: Class
subclass of: Epilepsy

BiLobar Epileptogenic Zone
type: Class
subclass of: Focal epileptogenic zone

Bicipital Space
type: Class
subclass of: Anatomical Compartment Space
label: Bicipital space of arm
label: Space of bicipital groove

Bifocal Encephalomalacia
type: Class
subclass of: Structural Cause

Big Toe
type: Class
subclass of: Toe

Bilateral Asymmetric Tonic Seizure
type: Class
subclass of: ConvulsiveMotorSeizure
comment: Motor (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Bilateral Seizure
type: Class
subclass of: Paroxysmal Event

Biological Substance
type: Class
subclass of: Independent Continuant
subclass of: Restriction
  on property: hasFunction
  some values from: Antigen

Bipolar Disorder
type: Class
subclass of: Neuropsychiatric Problem

Birth Injury
type: Class
subclass of: Structural Cause

Blurring of Grey White Matter Junction
type: Class
subclass of: Radiological Examination Finding

Bodily Feature
type: Class
subclass of: Independent Continuant

Subdivision of Body Proper
type: Class
subclass of: Cardinal Body Part Subdivision
comment: Subdivision of body proper. (source: FMA)

Body Temperature
type: Class
subclass of: Physiological Data
comment: CURE CDE (WG #1: Core and Death-Related Information)

Body Temperature Stimulus
type: Class
subclass of: Inducing Factor

Anterior Segment of Brodmann Area 3 Right Paracentral Lobule
type: Class

Brodmann Area 4 Right Postcentral Gyrus
type: Class
subclass of: Brodmann Area 4 Postcentral Gyrus

Bradycardic Seizure
type: Class
subclass of: Autonomic Seizure

Brain
type: Class
subclass of: Neuraxis Segment
subclass of: Restriction
  on property: hasPart
  all values from: Brain Segment
comment: The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals.[1] Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]

Brain Benign Neoplastic Cyst
type: Class
subclass of: Cerebral cyst (disorder)

Brain Dermoid Cyst
type: Class
subclass of: Cerebral cyst (disorder)
label: Dermoid cyst of brain (disorder)

Brain Epidermoid Cyst
type: Class
subclass of: Cerebral cyst (disorder)
see also: Epidermoid cyst of brain (disorder)

Brain Glial Neuronal Tumor
type: Class
subclass of: Brain Tumor
subclass of: Restriction
  on property: hasPart
  some values from: Cyst (disorder)

Brain Glial Tumor
type: Class
subclass of: Brain Tumor
label: Glial tumour of brain

Brain Neoplasm
type: Class
subclass of: Disorder
label: Neoplasm of brain

Brain Neural Tissue
type: Class
subclass of: Brain Segment
subclass of: Restriction
  on property: isConstitutionalPartOf
  some values from: Brain
comment: Portion of tissue which consists of neurons, neuroglia and vasculature. Examples: Neural tissue of brain, neural tissue of peripheral ganglion, neural tissue of nerve[FMA]

Brain Neural Tissue Segment
type: Class
subclass of: Brain Segment
comment: Fmaid 268523

Brain Neuronal Tumor
type: Class
subclass of: Brain Tumor

Brain Segment
type: Class
subclass of: Neuraxis Segment
comment: A multi-tissue structure that is part of a brain [Obol].

Brain Tumor
type: Class
subclass of: Structural Cause
subclass of: Restriction
  on property: isMarkedBy
  some values from: Blurring of Grey White Matter Junction

Brain Vascular
type: Class
subclass of: Brain Segment
subclass of: Restriction
  on property: isConstitutionalPartOf
  some values from: Brain

Brain Ventricle Ependymal Cyst
type: Class
subclass of: Cerebral cyst (disorder)
label: Ependymal cyst of ventricle of brain (disorder)

Brain Ventricular System
type: Class
subclass of: Brain Segment
subclass of: Restriction
  on property: isConstitutionalPartOf
  some values from: Brain

Brainstem Segment
type: Class
subclass of: Brain Segment
comment: Multi-tissue structure that has as its parts the medulla oblongata of the hindbrain and the tegmentum of the midbrain[ZFA,adopted].

Breach Rhythm
type: Class
subclass of: Epileptiform Benign Variant
comment: Breach rhythm refers to high-voltage activity that occurs in the region of a skull defect and have a spiky appearance and consist of sharply contoured arciform waveforms that usually have a frequency of 6-11 Hz.

Brisdelle
type: Class
subclass of: Drug Brand Name
see also: RxCUI 1430123

Brivaracetam
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Briviact
comment: Anti seizure medication
see also: RxCUI 1739745

Briviact
type: Class
subclass of: Drug Brand Name
see also: RxCUI 1739750

Brodmann Area
type: Class
subclass of: Cerebral Cortex Region

Brodmann Area 3 Frontal Lobe
type: Class
subclass of: Brodmann Area 3 Segment

Brodmann Area 3 Left Frontal Lobe
type: Class
subclass of: Brodmann Area 3 Frontal Lobe

Anterior Segment of Brodmann Area 3 Left Paracentral Lobule
type: Class

Brodmann Area 3 Left Postcentral Gyrus
type: Class
subclass of: Brodmann Area 3 Postcentral Gyrus

Brodmann Area 3 Left Precentral Gyrus
type: Class
subclass of: Brodmann Area 3 Precentral Gyrus

Anterior Segment of Brodmann Area 3 Paracentral Lobule
type: Class
subclass of: Brodmann Area 3 Segment

Brodmann Area 3 Postcentral Gyrus
type: Class
subclass of: Brodmann Area 3 Segment

Brodmann Area 3 Precentral Gyrus
type: Class
subclass of: Brodmann Area 3 Segment

Brodmann Area 3 Right Frontal Lobe
type: Class
subclass of: Brodmann Area 3 Frontal Lobe

Brodmann Area 3 Right Postcentral Gyrus
type: Class
subclass of: Brodmann Area 3 Postcentral Gyrus

Brodmann Area 3 Right Precentral Gyrus
type: Class
subclass of: Brodmann Area 3 Precentral Gyrus

Brodmann Area 3 Segment
type: Class
subclass of: Brodmann Area Segment

Brodmann Area 4 Frontal Lobe
type: Class
subclass of: Brodmann Area 4 Segment

Brodmann Area 4 Left Frontal Lobe
type: Class
subclass of: Brodmann Area 4 Frontal Lobe

Brodmann Area 4 Left Middle Frontal Gyrus
type: Class
subclass of: Brodmann Area 4 Middle Frontal Gyrus

Brodmann Area 4 Left Paracentral Lobule
type: Class
subclass of: Brodmann Area 4 Paracentral Lobule

Anterior Segment of Brodmann Area 4 Left Paracentral Lobule
type: Class

Posterior Segment of Brodmann Area 4 Left Paracentral Lobule
type: Class

Brodmann Area 4 Left Postcentral Gyrus
type: Class
subclass of: Brodmann Area 4 Postcentral Gyrus

Brodmann Area 4 Left Precentral Gyrus
type: Class
subclass of: Brodmann Area 4 Precentral Gyrus

Brodmann Area 4 Middle Frontal Gyrus
type: Class
subclass of: Brodmann Area 4 Segment

Brodmann Area 4 Paracentral Lobule
type: Class
subclass of: Brodmann Area 4 Segment

Anterior Segment of Brodmann Area 4 Paracentral Lobule
type: Class
subclass of: Brodmann Area 4 Segment

Posterior Segment of Brodmann Area 4 Paracentral Lobule
type: Class
subclass of: Brodmann Area 4 Segment

Brodmann Area 4 Postcentral Gyrus
type: Class
subclass of: Brodmann Area 4 Segment

Brodmann Area 4 Precentral Gyrus
type: Class
subclass of: Brodmann Area 4 Segment

Brodmann Area 4 Right Frontal Lobe
type: Class
subclass of: Brodmann Area 4 Frontal Lobe

Brodmann Area 4 Right Middle Frontal Gyrus
type: Class
subclass of: Brodmann Area 4 Middle Frontal Gyrus

Brodmann Area 4 Right Paracentral Lobule
type: Class
subclass of: Brodmann Area 4 Paracentral Lobule

Anterior Segment of Brodmann Area 4 Right Paracentral Lobule
type: Class

Posterior Segment of Brodmann Area 4 Right Paracentral Lobule
type: Class

Brodmann Area 4 Right Precentral Gyrus
type: Class
subclass of: Brodmann Area 4 Precentral Gyrus

Brodmann Area 4 Segment
type: Class
subclass of: Brodmann Area Segment

Brodmann Area Segment
type: Class
subclass of: Cerebral Cortex Region

Budeprion
type: Class
subclass of: Drug Brand Name
see also: RxCUI 581646

Buproban
type: Class
subclass of: Drug Brand Name
see also: RxCUI 581650

Bupropion
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Class
    intersection of: Bupropion Hydrobromide
    intersection of: Bupropion Hydrochloride
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Aplenzin
    union of: Budeprion
    union of: Buproban
    union of: Forfivo
    union of: Wellbutrin
    union of: Zyban
comment: Neuroleptic Drug
see also: RxCUI 42347

Bupropion Hydrobromide
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 993548

Bupropion Hydrochloride
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 203204

Burst Suppression
type: Class
subclass of: Special Pattern
comment: Burst suppression (BUS) refers to a form of periodic pattern in which cerebral activity is of an amplitude less than 10 uV between bursts of relatively higher-amplitude complexes.

CA1
type: Class
subclass of: Segment of hippocampus proper
label: CA1 field
label: CA1 field of hippocampus
label: Cornu Ammonis 1
label: Regio I cornus ammonis
label: Regio I hippocampi proprii
label: Regio superior of the hippocampus
label: Region I of Ammon's horn
label: Region I of hippocampus proper
see also: birnlex_1197 (Neurolex)

CA2
type: Class
subclass of: Segment of hippocampus proper
label: CA2 field of hippocampus
label: Cornu Ammonis 2
label: Regio II cornus ammonis
label: Regio II hippocampi proprii
label: Region II of Ammon's horn
label: Region II of hippocampus proper
see also: birnlex_1362 (Neurolex)

CA3
type: Class
subclass of: Segment of hippocampus proper
label: CA3 field
label: CA3 field of hippocampus
label: Cornu Ammonis 3
label: Regio III cornus ammonis
label: Regio III hippocampi proprii
label: Region III of Ammon's horn
label: Region III of hippocampus proper

CA4
type: Class
subclass of: Segment of hippocampus proper
label: Regio IV cornus ammonis
label: Regio IV hippocampi proprii
label: Region IV of Ammon's horn
label: Region IV of hippocampus proper

calcium voltage-gated channel subunit alpha1 A
type: Class
subclass of: Gene

calcium channel, voltage-dependent, T type, alpha 1H subunit
type: Class
subclass of: Gene

calcium channel, voltage-dependent, beta 4 subunit
type: Class
subclass of: Gene

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
type: Class
subclass of: Gene

chemokine (C-C motif) ligand 22
type: Class
subclass of: Gene

chemokine (C-C motif) ligand 23
type: Class
subclass of: Gene

chemokine (C-C motif) ligand 5
type: Class
subclass of: Gene

cyclin dependent kinase like 5
type: Class
subclass of: Gene

centrosomal protein 290
type: Class
subclass of: Gene

ceramide synthase
type: Class
subclass of: Gene

chromodomain helicase DNA binding protein 2
type: Class
subclass of: Gene

cholinergic receptor, nicotinic, alpha 2 (neuronal)
type: Class
subclass of: Gene

cholinergic receptor, nicotinic, alpha 4 (neuronal)
type: Class
subclass of: Gene
see also: Source: http://ghr.nlm.nih.gov/gene/CHRNA4

cholinergic receptor nicotinic alpha 7 subunit
type: Class
subclass of: Gene

cholinergic receptor, nicotinic, beta 2 (neuronal)
type: Class
subclass of: Gene

chloride channel, voltage-sensitive 2
type: Class
subclass of: Gene

CLN8, transmembrane ER and ERGIC protein
type: Class
subclass of: Gene

canopy FGF signaling regulator 3
type: Class
subclass of: Gene

contactin 2
type: Class
subclass of: Gene

carboxypeptidase A6
type: Class
subclass of: Gene

corticotropin releasing hormone
type: Class
subclass of: Gene

cysteine and serine rich nuclear protein 3
type: Class
subclass of: Gene

cystatin B
type: Class
subclass of: Gene

chemokine (C-X-C motif) ligand 10
type: Class
subclass of: Gene

chemokine (C-X-C motif) ligand 9
type: Class
subclass of: Gene

Cannabidiol
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasFunction
  some values from: Cannabinoid
subclass of: Restriction
  on property: hasTradename
  some values from: Epidiolex
comment: Anti seizure medication
comment: Antiepileptic drug
see also: RxCUI 2045371

Endocannabinoid
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasFunction
  some values from: Neuro Transmitter
comment: Anti seizure medication
comment: Anti-epileptic medication
see also: RxCUI C0006865

Carbamazepine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Carbatrol®
    union of: Tegretol®
    union of: Tegretol XR®
comment: Anti seizure medication
comment: Antiepileptic Drug
is defined by: Treats different types of seizures. Also used to treat nerve pain and bipolar disorder, also known as manic-depressive illness.
see also: RxCUI 2002

Carbatrol®
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 215879
comment: Treats different types of seizures. Also used to treat nerve pain and bipolar disorder, also known as manic-depressive illness.

Arrhythmia
type: Class
subclass of: ECG label
label: Cardiac Arrythmia

Cardiac Cell Culture
type: Class
subclass of: Cell Culture

Cardinal Body Part
type: Class
subclass of: Anatomical Structure
comment: Anatomical structure, which has as its direct parts instances of anatomical sets of organs and cardinal organ parts spatially associated with either the skull, vertebral column, or the skeleton of a limb; in their aggregate are surrounded by a part of the skin Examples: Head, body proper, right upper limb. (source: FMA)

Cardinal Body Part Subdivision
type: Class
subclass of: Anatomical Structure
comment: Anatomical structure, which is a subdivision of a cardinal body part; it may exclude bones; is demarcated from other subdivisions of the same cardinal body part by anatomical surfaces or lines or topographical references; together with other contiguous subdivisions of the same cardinal body part, it constitutes a cardinal body part. Examples: thorax, perineum, back of neck, forearm, hand, phalanx, nose, auricle of ear, scrotum.

Cardinal Brain Segment
type: Class
subclass of: Brain Segment

Cardinal Free Limb Segment
type: Class
subclass of: Free Limb Segment

Cardinal Organ Part
type: Class
subclass of: Anatomical Structure
comment: Fmaid 82472

Cartesian Spatial Coordinate Datum
type: Class
subclass of: Derived EEG Data

Cavernoma
type: Class
subclass of: Vascular Malformation
label: Cavernous Angioma

Celexa
type: Class
subclass of: Drug Brand Name
see also: RxCUI 215928

Cell Culture
type: Class
subclass of: Model System

Cell Part Cluster
type: Class
subclass of: Anatomical Cluster
comment: Anatomical cluster which has as direct parts cell parts from two or more cells.

Cenobamate
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Xcopri
comment: Anti seizure medication
see also: RxCUI 2265690

Central 10-10 System
type: Class
subclass of: 10-10 System

Central Myelin
type: Class
subclass of: Myelin

Central Nervous System Cyst
type: Class
subclass of: Cyst (disorder)
label: Cyst of central nervous system (disorder)

Cerebellum
type: Class
subclass of: Segment of Metencephalon Segment
comment: Part of the metencephalon that lies in the posterior cranial fossa behind the brain stem. It is concerned with the coordination of movement[MESH]. A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe[BTO]. Brain structure derived from the anterior hindbrain, and perhaps including posterior midbrain. The cerebellum plays a role in somatic motor function, the control of muscle tone, and balance[ZFA]

Cerebellum Hemisphere
type: Class
subclass of: Segment of Cerebellum
comment: the region of a cerebellar lobule that resides in either of the lateral sections of the cerebellum outside the vermis; in mammals, the vermis portion of the cerebellum has a foliation pattern along the AP axis that is distinct from the lateral cerebellar hemispheres

Cerebellum Neural Tissue
type: Class
subclass of: Brain Neural Tissue Segment
subclass of: Restriction
  on property: regional part of
  some values from: Metencephalon
subclass of: Restriction
  on property: isConstitutionalPartOf
  some values from: Cerebellum
comment: Fmaid 268535

Segment of Cerebellum
type: Class
subclass of: Segment of Metencephalon Segment
comment: A regional part of brain that is part of a cerebellum [Obol].

Cerebellum Vermis
type: Class
subclass of: Segment of Cerebellum
comment: the region of a cerebellar lobule that resides in the central section of the cerebellum between the two hemispheres; in humans, vermis lobule regions may be nearly continuous with the cerebellar hemisphere lobules dorsally but are separated by deeper longitudinal fissues in the ventral regions; in mammals, the vermis portion of the cerebellum has a foliation pattern along the AP axis that is distinct from the lateral cerebellar hemispheres

Cerebral Abcess
type: Class
subclass of: Infection

Cerebral Cortex Region
type: Class
subclass of: Organ Component Region
comment: The cerebral cortex is a structure within the brain that plays a key role in memory, attention, perceptual awareness, thought, language, and consciousness. It constitutes the outermost layer of the cerebrum. In preserved brains, it has a grey color, hence the name 'grey matter'. Grey matter is formed by neurons and their unmyelinated fibers, whereas the white matter below the grey matter of the cortex is formed predominantly by myelinated axons interconnecting different regions of the central nervous system. The human cerebral cortex is 2–4 mm (0.08–0.16 inches) thick. The surface of the cerebral cortex is folded in large mammals, such that more than two-thirds of the cortical surface is buried in the grooves, called 'sulci. ' The phylogenetically most recent part of the cerebral cortex, the neocortex, also called isocortex, is differentiated into six horizontal layers; the more ancient part of the cerebral cortex, the hippocampus (also called archicortex), has at most three cellular layers, and is divided into subfields. Relative variations in thickness or cell type (among other parameters) allow us to distinguish between different neocortical architectonic fields. The geometry of at least some of these fields seems to be related to the anatomy of the cortical folds, and, for example, layers in the upper part of the cortical ridges seem to be more clearly differentiated than in its deeper parts

Cerebral cyst (disorder)
type: Class
subclass of: Central Nervous System Cyst

Cerebral Hemisphere
type: Class
subclass of: Forebrain Segment
comment: "One of two bilateral, largely symmetrical organ subdivisions within the telencephalon which contain the cerebral cortex and cerebral white matter." [FMA v3.1]

CerebralHemisphereLobe
type: Class
subclass of: CerebralHemisphereSegment
comment: Subdivision of telencephalon which is one of five subdivisions of each hemisphere separated by both real landmarks (sulci and fissures) and arbitrary boundaries.

Cerebral Hemorrhage
type: Class
subclass of: Cerebrovascular Disease

Cerebral hydatid cyst
type: Class
subclass of: Cerebral cyst (disorder)
label: Cerebral hydatid cyst (disorder)

Cerebral Infarction
type: Class
subclass of: Cerebrovascular Disease

Segment of cerebral lobe
type: Class
subclass of: CerebralHemisphereSegment

Cerebral Palsy
type: Class
subclass of: Structural Cause

Cerebral Thrombosis
type: Class
subclass of: Disorder of Head

Cerebrovascular Disease
type: Class
subclass of: Structural Cause

Cerebyx
type: Class
subclass of: Drug Brand Name
comment: Antiepileptic drug
see also: RxCUI 134860

Child
type: Class
subclass of: Human
subclass of: Restriction
  on property: hasRecordedAge
  min qualified cardinality: 2
  on class: Year
subclass of: Restriction
  on property: hasRecordedAge
  max qualified cardinality: 12
  on class: Year
comment: a person of either sex between the time of birth and adolescence

Child attention deficit disorder
type: Class
subclass of: ADHD

Childhood Absence Epilepsy
type: Class
subclass of: Generalized Epilepsy
subclass of: Restriction
  on property: hasEtiology
  some values from: Genetic Mutation
subclass of: Restriction
  on property: hasIctalEpileptiformAbnormality
  some values from: Class
    union of: Slow Spike and Wave Complex
    union of: 3-Hz Spike-and-Wave Complex
subclass of: Restriction
  on property: hasInterIctalEpileptiformAbnormality
  some values from: Slow Spike and Wave Complex
subclass of: Restriction
  on property: hasPreferredMedication
  some values from: Class
    union of: Ethosuximide
    union of: Valproate
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: Dialeptic Seizure
subclass of: Restriction
  on property: hasAgeOfOnset
  min qualified cardinality: 4
  on class: Year
subclass of: Restriction
  on property: hasAgeOfOnset
  max qualified cardinality: 10
  on class: Year
label: Pyknolepsy

Childhood epilepsy with occipital paroxysms
type: Class
subclass of: Single Focal Epilepsy
subclass of: Restriction
  on property: hasEtiology
  some values from: Genetic Defect
subclass of: Restriction
  on property: hasIctalEpileptiformAbnormality
  some values from: EEG-SZ
subclass of: Restriction
  on property: hasPreferredMedication
  some values from: Clobazam
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: Class
    union of: Clonic Seizure
    union of: Visual Aura
subclass of: Restriction
  on property: hasAgeOfOnset
  min qualified cardinality: 4
  on class: Year
subclass of: Restriction
  on property: hasAgeOfOnset
  max qualified cardinality: 13
  on class: Year
label: Panayiotopoulos syndrome

Childhood Febrile Seizure
type: Class
subclass of: Paroxysmal Event

Benign childhood epilepsy with centrotemporal spikes
type: Class
subclass of: Single Focal Epilepsy
subclass of: Restriction
  on property: hasIctalEpileptiformAbnormality
  some values from: EEG-SZ
subclass of: Restriction
  on property: hasInterIctalEpileptiformAbnormality
  some values from: Class
    union of: Benign Focal Epileptiform Discharge of Childhood (BFEDC)
    union of: Slow Spike and Wave Complex
subclass of: Restriction
  on property: hasPreferredMedication
  some values from: Class
    union of: Gabapentin
    union of: Levetiracetam
    union of: Phenytoin
    union of: Valproate
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: Class
    union of: Aphasic Seizure
    union of: Autonomic Seizure
    union of: Simple Motor Seizure
    union of: Somatosensory Aura
    union of: SE
    union of: ConvulsiveMotorSeizure
subclass of: Restriction
  on property: hasAgeOfOnset
  min qualified cardinality: 1
  on class: Year
subclass of: Restriction
  on property: hasAgeOfOnset
  max qualified cardinality: 14
  on class: Year
label: Childhood Rolandic Epilepsy

Chlorpromazine
type: Class
subclass of: Drug Ingredient
comment: Antidepressant Drug
is defined by: Treats mental disorders, severe behavior disorders, severe hiccups, severe nausea and vomiting, and certain types of porphyria. Also used before and after surgery to relieve anxiety. Belongs to a class of drugs called phenothiazines.
see also: RxCUI 2403

Chlorprothixene
type: Class
subclass of: Drug Ingredient
comment: Antidepressant Drug
see also: RxCUI 2406

Choroid plexus cyst (disorder)
type: Class
subclass of: Cerebral cyst (disorder)

Chromosomal Abnormality
type: Class
subclass of: Genetic Defect

Chronic Dissociated Cell Culture
type: Class
subclass of: Disassociated Cell Culture
label: Chronic dissociated culture

Chronic Progressive Epilepsia Partialis Continua of Childhood
type: Class
subclass of: Single Focal Epilepsy
subclass of: Restriction
  on property: hasAssociatedMutationIn
  some values from: Class
    union of: chemokine (C-C motif) ligand 22
    union of: chemokine (C-C motif) ligand 23
    union of: chemokine (C-C motif) ligand 5
    union of: chemokine (C-X-C motif) ligand 10
    union of: chemokine (C-X-C motif) ligand 9
    union of: MUNC18-1
subclass of: Restriction
  on property: hasEtiology
  some values from: Class
    union of: Malformation of Cortical Development
    union of: Genetic Defect
    union of: Metabolic Cause
subclass of: Restriction
  on property: hasInterIctalEpileptiformAbnormality
  some values from: EEG-SZ
subclass of: Restriction
  on property: hasInterIctalEpileptiformAbnormality
  some values from: Class
    union of: Sharp Wave
    union of: Spike
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: ConvulsiveMotorSeizure
subclass of: Restriction
  on property: hasAgeOfOnset
  min qualified cardinality: 15
  on class: Year
subclass of: Restriction
  on property: hasAgeOfOnset
  max qualified cardinality: 15
  on class: Year
label: Rasmussen’s Encephalitis

Cingulate Epilepsy
type: Class
subclass of: Single Focal Epilepsy

Cingular
type: Class
subclass of: LimbicLobeGyrus

Cingular
type: Class
subclass of: Segment of cerebral lobe

Cipramil
type: Class
subclass of: Drug Brand Name
see also: RxCUI 151516

Citalopraam
type: Class
subclass of: Drug Brand Name
see also: RxCUI 540845

Citalopram
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Citalopram Hydrobromide
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Celexa
    union of: Cipramil
    union of: Citalopraam
comment: Neuroleptic Drug
see also: RxCUI 2556

Citalopram Hydrobromide
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 221078

Clinical Care Management
type: Class
subclass of: Patient Care Management

ClinicalDrugComponent
type: Class
subclass of: Independent Continuant
comment: Clinical drug component (RxNorm)

Clinical Evaluation
type: Class
subclass of: Clinical Care Management

Clinical Finding
type: Class
subclass of: Dependent Continuant

Clinical History Recording
type: Class
subclass of: Clinical Care Management

Clinical onset of seizure
type: Class
subclass of: Paroxysmal Event

Clinical Recommendation
type: Class
subclass of: Clinical Care Management

Clinical Seizure End
type: Class
subclass of: Paroxysmal Event

Clobazam
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Frisium
    union of: Onfi®
comment: Anti seizure medication
comment: Antiepileptic Drug
comment: Benzodiazepine
is defined by: Treats seizures in patients who have Lennox-Gastaut syndrome (LGS). This medicine is a benzodiazepine.
see also: RxCUI 21241

Clomicalm
type: Class
subclass of: Drug Brand Name
comment: RxCUI 892743
comment: http://purl.bioontology.org/ontology/RXNORM/892743

Clomipramine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Clomipramine Hydrochloride
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Anafranil
    union of: Clomicalm
comment: Neuroleptic Drug
see also: RxCUI 2597

Clomipramine Hydrochloride
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 81984

Clonazepam
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Klonopin
comment: Anti seizure medication
comment: Antiepileptic Drug
comment: Benzodiazepine
is defined by: Treats seizures, panic disorder, and anxiety. This medicine is a benzodiazepine.
see also: RxCUI 2598

Clonic Episode
type: Class
subclass of: Simple Motor Episode

Clonic Seizure
type: Class
subclass of: Simple Motor Seizure
comment: Clonic seizures consist of myoclonic jerks that recur at regular intervals of less than 1 to 2 seconds.
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Generalized Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Unknown Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
label: ConvulsiveMotorSeizure

End of Clonic Phase
type: Class
subclass of: Clonic Seizure

Onset of Clonic Phase
type: Class
subclass of: Clonic Seizure

Clonic Status
type: Class
subclass of: SimpleMotorStatus
comment: Convulsive status epilepticus (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Generalized Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Unknown Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Clonic Tonic Clonic Episode
type: Class
subclass of: Simple Motor Episode

Clonic-tonic-clonic Seizure
type: Class
subclass of: Simple Motor Seizure
comment: Clonic (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Generalized Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Generalized motor seizures in which there is an initial clonic phase preceding the tonic-clonic phase
comment: Tonic (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Unknown Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
label: ConvulsiveMotorSeizure

Clonic Tonic Clonic Status
type: Class
subclass of: SimpleMotorStatus
comment: Convulsive status epilepticus (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Generalized Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Unknown Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Clozapine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Clozaril
    union of: Fazaclo
    union of: Versacloz
comment: Antidepressant Drug
see also: RxCUI 2626

Clozaril
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 216102

CD3
type: Class
subclass of: Biological Substance
comment: CD3 Antigen
label: Cluster of Differentiation 3
label: T3 Antigens
label: T3 Complex

CD8
type: Class
subclass of: Biological Substance
label: CD8 Antigen
label: Cluster of Differentiation 8
label: Leu 2 Antigens
label: T8 Antigens, T Cell

Coagulopathy Hemorrhage
type: Class
subclass of: Intracerebral Hemorrhage

Cognitive Seizure
type: Class
subclass of: No Clinical Signs

Colloid brain cyst
type: Class
subclass of: Cerebral cyst (disorder)
label: Colloid brain cyst (disorder)

Combined dexamethasone-corticotropin releasing hormone test
type: Class
subclass of: Model System Depression Scale
label: DEXCRH

Compazine
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 203546

Complex Auditory Aura
type: Class
subclass of: Auditory Aura
comment: Complex auditory auras are those such as humming or chirping sounds as well as more elaborate phenomena such as music or voices.

Complex Auditory Aura Status
type: Class
subclass of: Auditory Aura Status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Complex Motor Episode
type: Class
subclass of: Motor Episode

Complex Motor Seizure
type: Class
subclass of: Motor Seizure
comment: Complex motor seizures consist of motor seizures during which the patient performs movements that imitate natural movements, are relatively complex, and tend to involve different body segments, which are moved in different planes.
comment: Motor (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Complex Motor Status
type: Class
subclass of: Motor Status

Complex Visual Hallucination
type: Class
subclass of: Visual Hallucination
comment: Simple visual hallucinations are crude, unformed elementary hallucinations including colored or colorless lights and shapes.

Complex Visual Hallucination Status
type: Class
subclass of: Visual Hallucination Status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Compro
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 285056

Compulsive Neurosis
type: Class
subclass of: Obsessive compulsive disorder

Concerta
type: Class
subclass of: Drug Brand Name
see also: RxCUI 284704

Conditioned stimulus
type: Class
subclass of: Inducing Factor

Congenital abnormality of skull and face bones (disorder)
type: Class
subclass of: Congenital anomaly of head (disorder)

Congenital anomaly of head (disorder)
type: Class
subclass of: Disorder of Head

Congenital anomaly of skull (disorder)
type: Class
subclass of: Congenital abnormality of skull and face bones (disorder)

Congenital Neurological Deficit
type: Class
subclass of: Disorder
label: Neurological disorder at the time of birth

Congenital cerebral cyst
type: Class
subclass of: Cerebral cyst (disorder)
label: Congenital cerebral cyst (disorder)

CASPR2
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: VGKC Associated Protein
label: Contactin Associated Protein 2

CASPR2AssociatedEncephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
subclass of: Restriction
  on property: hasAssociatedAntigen
  some values from: CASPR2
label: Contactin Associated Protein 2 Associated Encephalitis

CCFC
type: Class
subclass of: Model System Anxiety Scale
label: Contextual and cued fear conditioning

Continuous Slow
type: Class
subclass of: Slow Activity
comment: Continuous slow (CS) refers to the activity that occurs continuously (>80% of the time), is non-responsive to external stimuli, and clearly exceeds the amount considered physiologically normal for the patient's age.
label: Continuous Slow Activity

End of Continuous Slow
type: Class
subclass of: Continuous Slow

Onset of Continuous Slow
type: Class
subclass of: Continuous Slow

Corpus Callosotomy
type: Class
subclass of: Epilepsy Surgery

Cortical
type: Class
subclass of: Cell Culture
label: Cortical Cell Culture

Malformation of Cortical Development
type: Class
subclass of: Structural Cause

CorticalDyslamination
type: Class
subclass of: Malformation of Cortical Development
synonym: Abnormal cortical layering
synonym: Abnormality of cortical lamination

Cranial Cavity
type: Class
subclass of: Space of Compartment of Head
comment: "Space of compartment of head which is bound by the internal surface of the skull." (Foundational Model of Anatomy)

Cranial Fossa
type: Class
subclass of: Anatomical Compartment Space
label: http://purl.org/sig/ont/fma/fma321144

Cranium bifidum
type: Class
subclass of: Congenital anomaly of skull (disorder)

Cuneate Tubercle
type: Class
subclass of: Medulla Oblongata

Cyamemazine
type: Class
subclass of: Drug Ingredient
comment: Antidepressant Drug
see also: RxCUI 21877

CNPase
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: isUsedForMarkingCellularPattern
  some values from: Myelin
label: Cyclic Nucleotide Phosphodiesterase

Cyclin-dependent Kinase Inhibitor 2A
type: Class
subclass of: Biological Substance
label: p16
label: p16INK4 Genes

Cyclocephaly
type: Class
subclass of: Congenital abnormality of skull and face bones (disorder)

Cymbalta
type: Class
subclass of: Drug Brand Name
see also: RxCUI 482574

Cyst (disorder)
type: Class
subclass of: Disorder

Cystic leucoencephalopathy without megalencephaly
type: Class
subclass of: Cerebral cyst (disorder)

D-Tal
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 216326

DDHD2
type: Class
subclass of: Gene
see also: DDHD domain containing 2

DEP domain containing 5
type: Class
subclass of: Gene
subclass of: Restriction
  on property: hasSequenceVariant
  all values from: Class
    union of: Allele ID: 59810
    union of: Allele ID: 59812
    union of: Allele ID: 59814
    union of: Allele ID: 59815
    union of: Allele ID: 59809
comment: NM_001242897.2(DEPDC5):c.21C>G (p.Tyr7Ter) (source: Simple ClinVar)

DEPDC5 SequenceVariant
type: Class
subclass of: Genetic Variant
comment: Sequence variant of gene DEPDC5

Daily Seizure
type: Class
subclass of: Seizure Frequency Category
comment: Daily (i.e., 4 or more days per week)
comment: LA32854-4 (LOINC Code)

Daytrana
type: Class
subclass of: Drug Brand Name
see also: RxCUI 631252

Decreased Asymmetry Pattern
type: Class
subclass of: Asymmetry Pattern

DBS
type: Class
subclass of: Neurostimulation Therapy
label: Deep Brain Stimulation

DAMP
type: Class
subclass of: ADHD
label: Deficits in attention motor control and perception

Definite SUDEP
type: Class
subclass of: SUDEP
label: Definite Sudden Unexpected Death in Epilepsy

Degenerative abnormality (morphologic abnormality)
type: Class
subclass of: Abnormal tissue appearance
label: http://purl.bioontology.org/ontology/SNOMEDCT/107669003

Deja Vu
type: Class
subclass of: Psychic Aura
comment: Psychic auras in which the patient has the feeling of already having experienced the present situation.

Deja Vu Status
type: Class
subclass of: Pyschic Aura Status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Delayed membranous cranial ossification (disorder)
type: Class
subclass of: Cranium bifidum

DSPS
type: Class
subclass of: Sleep disorder
label: Delayed Sleep Phase Syndrome

Deletion
type: Class
subclass of: Variation Type
label: Deletion Variant

Delta Coma
type: Class
subclass of: Special Pattern
comment: Delta coma (DC) / Delta stupor (DS) refers to irregular, high voltage delta background activity in a comatose/stuporous patient.

DNERAssociatedEncephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
subclass of: Restriction
  on property: hasAssociatedAntigen
  some values from: DNER
label: Delta Notch Epidermal Growth Factor Receptor Associated Encephalitis

DNER
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: Neural Development
label: Delta Notch Like Epidermal Growth Factor Related Receptor

Delta Rhythm
type: Class
subclass of: Normal EEG Pattern
comment: Delta activity refers to activity with a frequency range of 1 to 3 Hz.

Delta Stupor
type: Class
subclass of: Special Pattern
comment: Delta coma (DC) / Delta stupor (DS) refers to irregular, high voltage delta background activity in a comatose/stuporous patient.

Dendritic Cell
type: Class
subclass of: Immune cell
label: interdigitating cell
label: veiled cell

Dentate Granule
type: Class
subclass of: Granule Cell
label: Dentate Granule Cell
label: DentateGranuleCell

Area dentata
type: Class
subclass of: Segment of hippocampus
label: Dentate gyrus
label: Fascia dentata
label: Fascia dentata (Crosby)
label: Fascia dentata hippocampi (Shantha)
label: Gyrus dentatus

Depacon
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 216458

Depakene®
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 203245
comment: Treats seizures (epilepsy). Also used to treat mood disorders and prevent migraine headaches. This medicine is an anticonvulsant.

Depakote®
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 216459
comment: Treat various types of seizure disorders. It is sometimes used together with other seizure medications.

Depakote ER®
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 284710
comment: An extended-release product used to prevent or reduce the occurrence of migraines. It is indicated for the prevention of migraine headaches in adults.

Derived EEG Data
type: Class
subclass of: EEG data

Desipramine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Class
    intersection of: Desipramine Dibudinate
    intersection of: Desipramine Hydrochloride
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Norpramin
    union of: Pertofrane
comment: Neuroleptic Drug
see also: RxCUI 3247

Desipramine Dibudinate
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 1099738

Desipramine Hydrochloride
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 3247

Desvenlafaxine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Desvenlafaxine Succinate
subclass of: Restriction
  on property: hasTradename
  some values from: Pristiq
comment: Neuroleptic Drug
see also: RxCUI 734064

Desvenlafaxine Succinate
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 683693

Developmental Epileptic Encephalopathy
type: Class
subclass of: Disorder

Developmental language disorder
type: Class
subclass of: Neuropsychiatric Problem
label: Pervasive Developmental Disorder

"Developmental entity which is a 3-D immaterial anatomical entity created during an organism's gestation." (Foundational Model of Anatomy)
type: Class
subclass of: Anatomical Space
label: Developmental Space

Developmental Status
type: Class
subclass of: Clinical Finding

Dexedrine
type: Class
subclass of: Drug Brand Name
see also: RxCUI 151612

Dexmethylphenidate
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Dexmethylphenidate Hydrochloride
subclass of: Restriction
  on property: hasTradename
  some values from: Focalin
comment: Neuroleptic Drug
see also: RxCUI 352372

Dexmethylphenidate Hydrochloride
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 353105

DextroStat
type: Class
subclass of: Drug Brand Name
see also: RxCUI 216555

Dextroamphetamine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Adderall
    union of: Dexedrine
    union of: DextroStat
    union of: LiquADD
    union of: ProCentra
    union of: Zenzedi
comment: Neuroleptic Drug
see also: RxCUI 3288

Dextroamphetamine Saccharate
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 221088

Dextroamphetamine Sulfate
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 3287

Di-Phen
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 216561

Diacomit
type: Class
subclass of: Drug Brand Name
see also: RxCUI C4722949

Dialeptic Episode
type: Class
subclass of: Non-Epileptic Seizure

Dialeptic Seizure
type: Class
subclass of: Epileptic Seizure
comment: Dialeptic seizures have alteration or loss of consciousness as the main ictal manifestation usually without loss of postural tone
comment: Nonmotor (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
label: Impaired Awareness

Dialeptic Status
type: Class
subclass of: SE
comment: Atypical (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Generalized Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Impaired Consciousness (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Typical (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Diastat
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 216586
comment: Treats anxiety, muscle spasms, seizures, and other medical conditions. This medicine is a benzodiazepine.

Benzodiazepine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Diastat
comment: Anti seizure medication
comment: Antiepileptic Drug
is defined by: Treats anxiety, muscle spasms, seizures, and other medical conditions. This medicine is a benzodiazepine.
see also: RxCUI 3322

Diencephalon
type: Class
subclass of: Forebrain Segment
subclass of: Restriction
  on property: regional part of
  some values from: Forebrain
comment: "Organ component of neuraxis that has as its parts the epithalamus, thalamus, hypothalamus, subthalamus. There is only one diencephalon." [FMA v3.1]

Diencephalon Anterior Tubercle
type: Class
subclass of: Diencephalon Zone

Diencephalon Neural Tissue
type: Class
subclass of: Brain Neural Tissue Segment
subclass of: Restriction
  on property: regional part of
  some values from: Forebrain Neural Tissue
subclass of: Restriction
  on property: isConstitutionalPartOf
  some values from: Diencephalon
comment: Fmaid 268527

Diencephalon Zone
type: Class
subclass of: Neuraxis Zone
subclass of: Restriction
  on property: isPartOf
  some values from: Diencephalon
comment: A regional part of brain that is part of a diencephalon

Diffuse Astrocytoma
type: Class
subclass of: Astrocytic
subclass of: Restriction
  on property: hasAssociatedMutationIn
  some values from: Class
    union of: MYB proto-oncogene, transcription factor
    union of: MYB proto-oncogene like 1
subclass of: Restriction
  on property: WHO grading
  some values from: WHO_II

Diffuse Glioma
type: Class
subclass of: Brain Glial Tumor

Diffuse High Grade Glioma
type: Class
subclass of: Astrocytic
subclass of: Restriction
  on property: hasAssociatedMutationIn
  some values from: Class
    union of: H3.3 histone A
    union of: Isocitrate Dehydrogenase (NADP(+)) 1
    union of: Isocitrate Dehydrogenase (NADP(+)) 2

Diffuse Leptomeningeal Glioneuronal Tumor
type: Class
subclass of: Brain Glial Neuronal Tumor

Diffuse Low Grade Glioma
type: Class
subclass of: Astrocytic
subclass of: Restriction
  on property: hasAssociatedMutationIn
  some values from: Fibroblast Growth Factor Receptor

Diffuse Midline Glioma
type: Class
subclass of: Astrocytic
subclass of: Restriction
  on property: hasAssociatedMutationIn
  some values from: H3.3 histone A
subclass of: Restriction
  on property: WHO grading
  some values from: Class
    union of: WHO_III
    union of: WHO_IV
label: H3 K27M-mutant

DTI
type: Class
subclass of: StructuralImaging

DWI
type: Class
subclass of: StructuralImaging

CRAM
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: Neural Development
label: CRMP-5
label: CRMP3-associated molecule
label: DPYSL5
label: DRP-5
label: Dihydropyrimidinase Related Protein 5
label: ULIP6
label: UNC33-like phosphoprotein 6
label: collapsin response mediator protein 5

DPYSL5AssociatedEncephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
subclass of: Restriction
  on property: hasAssociatedAntigen
  some values from: CRAM
label: Dihydropyrimidinase Related Protein 5 Associated Encephalitis

Dilantin®
type: Class
subclass of: Drug Brand Name
comment: Treats seizures. This medicine is an anticonvulsant.
see also: RxCUI 202740

DPPX
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: VGKC Associated Protein
label: Dipeptidyl Peptidase Like Protein 6

DPPXAssociatedEncephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
subclass of: Restriction
  on property: hasAssociatedAntigen
  some values from: DPPX
label: Dipeptidyl Peptidase like Protein 6 Associated Encephalitis

Diplopia Status
type: Class
subclass of: Visual Illusion Status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Disassociated Cell Culture
type: Class
subclass of: Cell Culture

DRDCC
type: Class
subclass of: Cell Culture
label: Disassociated Rodent Derived Cell Culture

Disorder
type: Class
subclass of: Dependent Continuant

Disorder of Head
type: Class
subclass of: Disorder

DistalFreeLimbSegment
type: Class
subclass of: Cardinal Free Limb Segment
comment: Distal Free Limb Segment

Divalproex Sodium
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 266856

Donnapine
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 216723

Donnatal
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 115141

Dopamine hydrochloride
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: Neuro Transmitter

Dorsal Hypothalamic Area
type: Class
subclass of: Hypothalamus Zone

Dosulepin
type: Class
subclass of: Drug Ingredient
comment: Neuroleptic Drug
see also: RxCUI 3634

Dothiepin Hydrochloride
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 142133

Doxepin
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Doxepin Hydrochloride
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Prudoxin
    union of: Silenor
    union of: Zonalon
comment: Neuroleptic Drug
see also: RxCUI 3638

Doxepin Hydrochloride
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 203179

Dravet Syndrome
type: Class
subclass of: Generalized Epilepsy
subclass of: Restriction
  on property: hasAgeOfOnset
  some values from: Infant
subclass of: Restriction
  on property: hasAssociatedDisorder
  some values from: Class
    union of: Autism Spectrum Disorder
    union of: Mental Retardation
subclass of: Restriction
  on property: hasAssociatedMutationIn
  some values from: sodium channel, voltage-gated, type I, alpha subunit
subclass of: Restriction
  on property: hasEtiology
  some values from: Genetic Mutation
subclass of: Restriction
  on property: hasIctalEpileptiformAbnormality
  some values from: EEG-SZ
subclass of: Restriction
  on property: hasInterIctalEpileptiformAbnormality
  some values from: Class
    union of: PolySpikes
    union of: Sharp Wave
    union of: Spike
    union of: Spike and Wave Complex
subclass of: Restriction
  on property: hasPreferredMedication
  some values from: Class
    union of: Clobazam
    union of: Clonazepam
    union of: Levetiracetam
    union of: Topiramate
    union of: Valproate
    union of: Zonisamide
subclass of: Restriction
  on property: hasPrematureMortality
  some values from: SUDEP
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: Class
    union of: ConvulsiveMotorSeizure
subclass of: Restriction
  on property: isTypeOfSyndrome
  some values from: Developmental Epileptic Encephalopathy
label: SMEI
label: Severe Myoclonic Epilepsy In Infancy
label: SevereMyoclonicEpilepsyInInfancy

Drop Attack
type: Class
subclass of: Clinical Finding
subclass of: Restriction
  on property: isCausedBy
  some values from: Class
    union of: Atonic Seizure
    union of: Clonic Seizure
    union of: ConvulsiveMotorSeizure
label: Drop Seizure
label: DropAttack

Droperidol
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Inapsine
comment: Antidepressant Drug
is defined by: Treats anxiety, nausea, and vomiting before and after surgical and diagnostic procedures.
see also: RxCUI 3648

Drug Brand Name
type: Class
subclass of: ClinicalDrugComponent

Drug Dose Form
type: Class
subclass of: ClinicalDrugComponent

Drug Ingredient
type: Class
subclass of: ClinicalDrugComponent

Dual pathology
type: Class
subclass of: Cortical Dysplasia
subclass of: Class
  complement of: Restriction
    on property: isAdjacentTo
    some values from: Hippocampal sclerosis

Duloxetine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Duloxetine Hydrochloride
subclass of: Restriction
  on property: hasTradename
  some values from: Cymbalta
comment: Neuroleptic Drug
see also: RxCUI 72625

Duloxetine Hydrochloride
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 476250

Duplication
type: Class
subclass of: Variation Type
label: Duplication Variant

dynamic contrast-enhanced MRI
type: Class
subclass of: MR

DNET
type: Class
subclass of: Brain Glial Neuronal Tumor
subclass of: Restriction
  on property: WHO grading
  some values from: WHO grade I
subclass of: Restriction
  on property: hasAssociatedMutationIn
  all values from: Fibroblast Growth Factor Receptor
label: DNT
label: Dysembryoplastic Neuroepithelial Tumor

Dysmetropsia Status
type: Class
subclass of: Visual Illusion Status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Dysmorphic Neurons
type: Class
subclass of: Neuron
subclass of: Restriction
  on property: isMarkedBy
  some values from: Class
    union of: NF-M20 PhosphorylationIndependent
    union of: pS6
comment: Dysmorphic cells derive from radial glial progenitor cells (https://academic.oup.com/brain/article/130/9/2267/291780)

EEG 128Channel Topographic Wave Plot
type: Class
subclass of: EEG Topographic Wave Plot

EEG 16 Channel Topographic Wave Plot
type: Class
subclass of: EEG Topographic Wave Plot

EEG 256 Channel Topographic Wave Plot
type: Class
subclass of: EEG Topographic Wave Plot

EEG 32 Channel Topographic Wave Plot
type: Class
subclass of: EEG Topographic Wave Plot

EEG 64 Channel Topographic Wave Plot
type: Class
subclass of: EEG Topographic Wave Plot

EEG 8 Channel Topographic Wave Plot
type: Class
subclass of: EEG Topographic Wave Plot

EEG Current Source Density Map
type: Class
subclass of: EEG Topographic Map

EEG Field Potential Map
type: Class
subclass of: EEG Topographic Map

EEG Scalp Difference Map
type: Class
subclass of: EEG Field Potential Map

EEG Scalp Field Potential Map
type: Class
subclass of: EEG Field Potential Map

EEG Seizure End
type: Class
subclass of: EEG event

EEGSeizureOnset
type: Class
subclass of: EEG event
comment: EEG Seizure Onset

EEG Statistical T Map
type: Class
subclass of: EEG Field Potential Map

End of EEG Suppression
type: Class
subclass of: EEG Suppression

Onset of Seizure Onset
type: Class
subclass of: EEG Suppression

EEG Topographic Map
type: Class
subclass of: Derived EEG Data

EEG Topographic Wave Plot
type: Class
subclass of: Derived EEG Data

EEG Wave Plot
type: Class
subclass of: EEG Topographic Map

EF-hand domain (C-terminal) containing 1
type: Class
subclass of: Gene

EPM2A, laforin glucan phosphatase
type: Class
subclass of: Gene

Early Infantile Epileptic Encephalopathy With Suppression Bursts
type: Class
subclass of: Generalized Epilepsy
subclass of: Restriction
  on property: isTypeOfSyndrome
  some values from: Developmental Epileptic Encephalopathy

Early Myoclonic Encephalopathy
type: Class
subclass of: Generalized Epilepsy
subclass of: Restriction
  on property: isTypeOfSyndrome
  some values from: Developmental Epileptic Encephalopathy

Elavil
type: Class
subclass of: Drug Brand Name
see also: RxCUI 42940

ECG label
type: Class
subclass of: Electrophysiological data
label: Electrocardiography Data
see also: CURE CDE WG#3: ECG

Electrocerebral Inactivity
type: Class
subclass of: Special Pattern
synonym: ECI

Electrode
type: Class
subclass of: Independent Continuant
see also: Electrode device

Electrode A1
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Left Temporal

Electrode A2
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Right Temporal

Electrode AF3
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: LeftFrontalLobe

Electrode AF4
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: RightFrontalLobe

Electrode AF7
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: LeftFrontalLobe

Electrode AF8
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: RightFrontalLobe

Electrode AFz
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: FrontalLobe

AL3
type: Class
subclass of: Intracranial Electrode
label: Electrode AL3

AL4
type: Class
subclass of: Intracranial Electrode
label: Electrode AL4

AL5
type: Class
subclass of: Intracranial Electrode
label: Electrode AL5

AM5
type: Class
subclass of: Intracranial Electrode
label: Electrode AM5

AM6
type: Class
subclass of: Intracranial Electrode
label: Electrode AM6

AM7
type: Class
subclass of: Intracranial Electrode
label: Electrode AM7

AP5
type: Class
subclass of: Intracranial Electrode
label: Electrode AP5

AP6
type: Class
subclass of: Intracranial Electrode
label: Electrode AP6

AP7
type: Class
subclass of: Intracranial Electrode
label: Electrode AP7

Electrode C2
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: RightFrontalLobe

Electrode C3
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: LeftFrontalLobe

Electrode C4
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: RightFrontalLobe

Electrode C5
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: LeftFrontalLobe

Electrode C6
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: RightFrontalLobe

Electrode CI4
type: Class
subclass of: Scalp Electrode

Electrode CI5
type: Class
subclass of: Scalp Electrode

Electrode CI6
type: Class
subclass of: Scalp Electrode

Electrode CP1
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Left Parietal

Electrode CP2
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Right Parietal

Electrode CP3
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Left Parietal

Electrode CP4
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Right Parietal

Electrode CP5
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Left Parietal

Electrode CP6
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Right Parietal

Electrode CPz
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Parietal

Electrode Cz
type: Class
subclass of: Scalp Electrode

Electrode F1
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: LeftFrontalLobe

Electrode F10
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: RightFrontalLobe

Electrode F2
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: RightFrontalLobe

Electrode F3
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: LeftFrontalLobe

Electrode F4
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: RightFrontalLobe

Electrode F5
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: LeftFrontalLobe

Electrode F6
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: RightFrontalLobe

Electrode F7
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: LeftFrontalLobe

Electrode F8
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: RightFrontalLobe

Electrode F9
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: LeftFrontalLobe

Electrode FC1
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: LeftFrontalLobe

Electrode FC2
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: RightFrontalLobe

Electrode FC3
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: LeftFrontalLobe

Electrode FC4
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: RightFrontalLobe

Electrode FC5
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: LeftFrontalLobe

Electrode FC6
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: RightFrontalLobe

Electrode FCz
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: FrontalLobe

Electrode FP1
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Left Frontal Pole

Electrode FP2
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Right Frontal Pole

Electrode FPz
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Frontal Pole

Electrode FT10
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Right Temporal

Electrode FT7
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Left Temporal

Electrode FT8
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Right Temporal

Electrode FT9
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Left Temporal

Electrode Fz
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: FrontalLobe

Electrode Iz
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Inion

Electrode Nz
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Nasion

Electrode O1
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Left Occipital

Electrode O2
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Right Occipital

Electrode Oz
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Occipital

Electrode P1
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Left Parietal

Electrode P10
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Right Parietal

Electrode P2
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Right Parietal

Electrode P3
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Left Parietal

Electrode P4
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Right Parietal

Electrode P5
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Left Parietal

Electrode P6
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Right Parietal

Electrode P7
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Left Parietal

Electrode P8
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Right Parietal

Electrode P9
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Left Parietal

Electrode PL4
type: Class
subclass of: Scalp Electrode

Electrode PL5
type: Class
subclass of: Scalp Electrode

Electrode PL6
type: Class
subclass of: Scalp Electrode

Electrode PO3
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Left Parietal

Electrode PO4
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Right Parietal

Electrode PO7
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Left Parietal

Electrode PO8
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Right Parietal

Electrode POz
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Parietal

Electrode Placement System
type: Class
subclass of: Dependent Continuant
comment: Placement system for electrodes to record brain activity.
see also: CURE CDE WG#3: Electrode Placement

Electrode Pz
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Parietal

Electrode SP1
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Left Temporal

Electrode SP2
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Right Temporal

Electrode T10
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Right Temporal

Electrode T3
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Left Temporal

Electrode T4
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Right Temporal

Electrode T5
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Left Temporal

Electrode T6
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Right Temporal

Electrode T7
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Left Temporal

Electrode T8
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Right Temporal

Electrode T9
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Left Temporal

Electrode TP10
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Right Temporal

Electrode TP7
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Left Temporal

Electrode TP8
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Right Temporal

Electrode TP9
type: Class
subclass of: Scalp Electrode
subclass of: Restriction
  on property: isLocatedAt
  some values from: Left Temporal

Electrodecrement
type: Class
subclass of: Inter Ictal Pattern
comment: A focal or generalized flattening of the EEG due to a sudden desynchronization of brain activity

EEG
type: Class
subclass of: Electrophysiological Modality
label: Electroencephalography

EEG event
type: Class
subclass of: EEG Pattern
comment: Clinical event annotation terms used to annotate the EEG.
label: Electroencephalogram Event

Electroencephalogram Finding
type: Class
subclass of: Clinical Finding

EEG Pattern
type: Class
subclass of: Dependent Continuant
subclass of: Restriction
  on property: isLocatedAt
  some values from: Anatomical Structure
label: EEGPattern
label: Electroencephalogram Pattern

EEG Suppression
type: Class
subclass of: EEG Pattern
label: Electroencephalogram Suppression

EEG data
type: Class
subclass of: Electrophysiological data
label: Electroencephalography Data

Electrographic Seizure
type: Class
subclass of: Ictal Pattern
comment: Electrographic seizure has no clinical correlate.

Electrophysiological data
type: Class
subclass of: Physiological Data
comment: Data of electrophysiological phenomena

Electrophysiological Modality
type: Class
subclass of: Nervous System Measurement Modality

Simple Auditory Aura
type: Class
subclass of: Auditory Aura
comment: Elementary auditory auras involve simple tones such as buzzing or ringing.

Elementary Auditory Aura Status
type: Class
subclass of: Auditory Aura Status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

EPM
type: Class
subclass of: Model System Anxiety Scale
label: Elevated plus maze

Emetic Seizure
type: Class
subclass of: Autonomic Seizure

Emotional Seizure
type: Class
subclass of: No Clinical Signs

Craniocele
type: Class
subclass of: Cranium bifidum
label: http://purl.bioontology.org/ontology/SNOMEDCT/55999004

Endocrine Disorder
type: Class
subclass of: Disorder

Endocrine response to the immobilization stress
type: Class
subclass of: Model System Depression Scale
label: IMS

Endocytosis
type: Class
subclass of: Protein Function
comment: "A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle." (Gene Ontology)

Endothelial Cell
type: Class
subclass of: Cell

mature eosinocyte
type: Class
subclass of: Granular Leukocyte
label: mature eosinophil leucocyte
label: polymorphonuclear leucocyte
label: polymorphonuclear leukocyte

Ependymal Tumor
type: Class
subclass of: NonDiffuse Glioma

Ependymoma RELA-Fusion Positive
type: Class
subclass of: Ependymal Tumor
subclass of: Restriction
  on property: hasAssociatedMutationIn
  some values from: RELA proto-oncogene, NF-kB subunit
subclass of: Restriction
  on property: WHO grading
  some values from: WHO_III

Epidiolex
type: Class
subclass of: Drug Brand Name
comment: Antiepileptic drug
see also: RxCUI 2058901

Epilepsy
type: Class
subclass of: Disorder
comment: "A disorder characterized by recurrent seizures." (SNOMED CT)

Epilepsy Of Infancy With Migrating Focal Seizures
type: Class
subclass of: Multi Focal Epilepsy

Epilepsy Surgery
type: Class
subclass of: Therapy

Epilepsy With Continuous Spike-waves During Slow-wave Sleep
type: Class
subclass of: Undetermined Epilepsy

Epilepsy With General Tonic Clonic Seizure On Awakening
type: Class
subclass of: Generalized Epilepsy
subclass of: Restriction
  on property: hasAssociatedMutationIn
  some values from: EF-hand domain (C-terminal) containing 1
subclass of: Restriction
  on property: hasEtiology
  some values from: Genetic Defect
subclass of: Restriction
  on property: hasIctalEpileptiformAbnormality
  some values from: Class
    union of: PolySpikes
    union of: Spike
subclass of: Restriction
  on property: hasInterIctalEpileptiformAbnormality
  some values from: Class
    union of: PolySpikes
    union of: Spike
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: ConvulsiveMotorSeizure
subclass of: Restriction
  on property: hasAgeOfOnset
  min qualified cardinality: 13
  on class: Year
comment: Specific type of Idiopathic Generalized Epilepsies (IGE)

Epilepsy With Myoclonic-astatic Seizures
type: Class
subclass of: Generalized Epilepsy

Epilepsy With Myoclonic Absences
type: Class
subclass of: Generalized Epilepsy

EpilepsyZone
type: Class
subclass of: Independent Continuant
comment: Epilepsy zone
comment: https://pubmed.ncbi.nlm.nih.gov/11522572/

Epileptic Episode
type: Class
subclass of: Simple Motor Episode

Epileptic Seizure
type: Class
subclass of: Paroxysmal Event
disjoint with: Non-Epileptic Seizure
comment: An epileptic seizure, occasionally referred to as a fit, is defined as a transient symptom of "abnormal excessive or synchronous neuronal activity in the brain".

ConvulsiveMotorSeizure
type: Class
subclass of: Simple Motor Seizure
comment: Epileptic spasms consists of a more or less sustained contractions of axial muscles leading to flexion of the trunk and abduction and elevation of both arms in "salaam" positions.
comment: Generalized Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Unknown Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
label: Epileptic Spasm
label: Infantile spasm syndrome
label: Spasm

Epileptic Spasm Status
type: Class
subclass of: SimpleMotorStatus
comment: Myoclonic (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Epileptiform Benign Variant
type: Class
subclass of: Benign EEG Pattern
comment: Eileptiform benign variant have an epileptiform appearance but are not epileptogenic, that is, they are not associated with seizures.

Epileptiform Pattern
type: Class
subclass of: Abnormal EEG Pattern
comment: Epileptiform patterns refers to the discharges that are easily differentiated from background activity, are usually seen in patients with epilepsy and indicate a tendency to epilepsy.

Epileptogenic Lesion
type: Class
subclass of: EpilepsyZone
comment: Potentially epileptogenic lesion visible on anatomical neuroimaging.

Epileptogenic Zone
type: Class
subclass of: EpilepsyZone
subclass of: Restriction
  on property: isLocatedAt
  some values from: Anatomical Structure
comment: Area of cortex that is indispensable to the generation of clinical epileptic seizures.

Epilim
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 151706

Epithelial Cell
type: Class
subclass of: Somatic Cell

Epithelial Cyst
type: Class
subclass of: Brain Tumor

Antigen
type: Class
subclass of: Biological Substance
label: Antigenic determinant

Escitalopram
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Escitalopram Oxalate
subclass of: Restriction
  on property: hasTradename
  some values from: Lexapro
comment: Neuroleptic Drug
see also: RxCUI 321988

Escitalopram Oxalate
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 353108

Eslicarbazepine Acetate
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 1482501

Ethosuximide
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Zarontin®
comment: Anti seizure medication
comment: Antiepileptic Drug
is defined by: Used for the control of absence (petit mal) epilepsy.
see also: RxCUI 4135

Aetiology
type: Class
subclass of: Dependent Continuant

Etrafon
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 1372742

Euthasol
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 1100450

Excessive Fast Pattern
type: Class
subclass of: Special Pattern
comment: Excessive fast (EF) refers to an EEG recording in which at least 50 % of the awake recording is dominated by generalized beta activity of amplitude exceeding 50 uV (reference derivation)

External
type: Class
subclass of: Anatomical Coordinate

Extracted ERP Pattern
type: Class
subclass of: Averaged EEG Data

Eye
type: Class
subclass of: Subdivision of Face
comment: OM: Generally the eye is considered synonymous with the eyeball. In clinical practice, eye surgeries include not only procedures on the eyeball alone but also on the extraocular muscles, the eyelids and the other extraocular (both intraorbital and extraorbital) structures. Classification of eye diseases follows the same approach. The decision on classifying the eye as a body part subdivision (part of face) is partly based on this. A consideration would be to name the body part subdivision as the "ocular region" or "ocular part of face" and use "eye" as a synonym of "eyeball". (source: FMA)

Eyelid myoclonia
type: Class
subclass of: ConvulsiveMotorSeizure

Ezogabine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Potiga
comment: Antiepileptic Drug
is defined by: Used to treat partial-onset seizures in adults.
see also: RxCUI 1112990

FANCD2 and FANCI associated nuclease 1
type: Class
subclass of: Gene

Fibroblast Growth Factor Receptor
type: Class
subclass of: Gene

FYCOMPA
type: Class
subclass of: Drug Brand Name
see also: RxCUI 1356558

Face
type: Class
subclass of: Subdivision of Head
comment: Subdivision of head which consists of the viscerocranium and all layers superficial to it. Examples: There is only one face. (source: FMA)

Subdivision of Face
type: Class
subclass of: Subdivision of Head

Familial Focal Epilepsy With Variable Foci
type: Class
subclass of: Multi Focal Epilepsy

Family History of Seizures
type: Class
subclass of: Genetic Defect

Fanapt
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 848723

Fanatrex
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 997847

Fast Alpha Variant
type: Class
subclass of: Alpha Variant
comment: Occurs at a harmonic twice that of the alpha range

Fast Ripple
type: Class
subclass of: High Frequency Oscillation
comment: Oscillations between 250 and 500 Hz, Brain (2007) 130 (9): 2354-2366. doi: 10.1093/brain/awm149

Fazaclo
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 542974

Febrile Seizure
type: Class
subclass of: Temperature Induced Seizure
subclass of: Restriction
  on property: isManifestedBy
  some values from: Class
    union of: ConvulsiveMotorSeizure
comment: Seizures provoked by temperature

Felbamate
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Felbatol®
comment: Anti seizure medication
comment: Antiepileptic Drug
is defined by: Used alone or together with other medicines to control partial seizures in patients who have failed other treatments. Also given to children with a type of epilepsy called Lennox-Gastaut syndrome. Belongs to a class of medicines called anticonvulsants.
see also: RxCUI 24812

Felbatol®
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 224900
comment: Used alone or together with other medicines to control partial seizures in patients who have failed other treatments. Also given to children with a type of epilepsy called Lennox-Gastaut syndrome. Belongs to a class of medicines called anticonvulsants.

Fenfluramine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: fenfluramine hydrochloride
subclass of: Restriction
  on property: hasTradename
  some values from: Fintepla
comment: Anti seizure medication
see also: RxCUI 4328

fenfluramine hydrochloride
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI C0282179

Fibrillary Astrogliosis
type: Class
subclass of: Astrogliosis
subclass of: Restriction
  on property: hasValue
  qualified cardinality: 2
  on data range: integer

Finger
type: Class
subclass of: Hand Segment
comment: Subdivision of the hand demarcated from the hand proper by the skin crease in line with the distal edge of finger webs. Examples: thumb, right middle finger, left little finger. (source: FMA)

Fintepla
type: Class
subclass of: Drug Brand Name
see also: RxCUI C5239669

Flash Light Stimulus
type: Class
subclass of: Light

FLAIR
type: Class
subclass of: StructuralImaging

Fluoxetine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Fluoxetine Hydrochloride
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Prozac
    union of: Rapiflux
    union of: Reconcile
    union of: Sarafem
    union of: Symbyax
comment: Neuroleptic Drug
see also: RxCUI 4493

Fluoxetine Hydrochloride
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 227224

Flupenthixol
type: Class
subclass of: Drug Ingredient
comment: Antidepressant Drug
see also: RxCUI 4495

Fluphenazine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Permitil
    union of: Prolixin
comment: Antidepressant Drug
is defined by: Treats schizophrenia and different types of behavior problems. Belongs to a class of drugs called phenothiazines.
see also: RxCUI 4496

Fluvoxamine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Fluvoxamine Maleate
subclass of: Restriction
  on property: hasTradename
  some values from: Luvox
comment: Neuroleptic Drug
see also: RxCUI 42355

Fluvoxamine Maleate
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 203143

Cortical Dysplasia
type: Class
subclass of: Malformation of Cortical Development
label: FCD
label: Focal Cortical Dysplasia

Focal Cortical Dysplasia Type I
type: Class
subclass of: Cortical Dysplasia
comment: FCD Type I (Isolated)

FCD Type IA
type: Class
subclass of: Focal Cortical Dysplasia Type I
subclass of: Restriction
  on property: hasNeuroPathologyFinding
  some values from: Abnormal Radial Migration
comment: FCD Type IA (Abnormal Radial Cortical Lamination)
label: Focal Cortical Dysplasia Type IA

FCD Type IB
type: Class
subclass of: Focal Cortical Dysplasia Type I
subclass of: Restriction
  on property: hasNeuroPathologyFinding
  some values from: Abnormal tangential cortical lamination
comment: FCD Type IB (Abnormal Tangential Cortical Lamination)
label: Focal Cortical Dysplasia Type IB

FCD Type IC
type: Class
subclass of: Focal Cortical Dysplasia Type I
subclass of: Restriction
  on property: hasNeuroPathologyFinding
  some values from: Class
    intersection of: Abnormal Radial Migration
    intersection of: Abnormal tangential cortical lamination
comment: FCD Type IC (Abnormal Radial and Tangential Cortical Lamination)
label: Focal Cortical Dysplasia Type IC

Focal Cortical Dysplasia Type II
type: Class
subclass of: Cortical Dysplasia
comment: FCD Type II (Isolated)

FCD Type IIA
type: Class
subclass of: Focal Cortical Dysplasia Type II
subclass of: Restriction
  on property: hasNeuroPathologyFinding
  some values from: Dysmorphic Neurons
comment: FCD Type IIA (Dysmorphic Neuron)
label: Focal Cortical Dysplasia Type IIA

FCD Type IIB
type: Class
subclass of: Focal Cortical Dysplasia Type II
subclass of: Class
  union of: Restriction
    on property: hasNeuroPathologyFinding
    some values from: Loss of myelination
  union of: Restriction
    on property: hasNeuroPathologyFinding
    some values from: Class
      intersection of: Balloon Cell
      intersection of: Dysmorphic Neurons
comment: FCD Type IIB (Dysmorphic Neurons and Balloon Cell)
label: Focal Cortical Dysplasia Type IIB

Focal Cortical Dysplasia Type III
type: Class
subclass of: Cortical Dysplasia
comment: FCD Type III (Associated with Principal Lesion)

FCD Type IIIA
type: Class
subclass of: Focal Cortical Dysplasia Type III
subclass of: Class
  intersection of: Restriction
    on property: hasNeuroPathologyFinding
    some values from: Class
      intersection of: CorticalDyslamination
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Temporal
  intersection of: Restriction
    on property: isAdjacentTo
    some values from: Hippocampal sclerosis
comment: FCD Type IIIA (Cortical Lamination Abnormality in the Temporal Lobe Associated with Hippocampal Sclerosis)
label: Focal Cortical Dysplasia Type IIIA

FCD Type IIIB
type: Class
subclass of: Focal Cortical Dysplasia Type III
subclass of: Restriction
  on property: hasNeuroPathologyFinding
  some values from: Class
    intersection of: CorticalDyslamination
    intersection of: Class
      union of: Brain Glial Neuronal Tumor
      union of: Restriction
        on property: isAdjacentTo
        all values from: Brain Glial Tumor
comment: FCD Type IIIB (Cortical Lamination Adjacent to a Glial or Glioneuronal Tumor)
label: Focal Cortical Dysplasia Type IIIB

FCD Type IIIC
type: Class
subclass of: Focal Cortical Dysplasia Type III
subclass of: Restriction
  on property: hasNeuroPathologyFinding
  some values from: Class
    intersection of: CorticalDyslamination
    intersection of: Restriction
      on property: isAdjacentTo
      all values from: Vascular Malformation
comment: FCD Type IIIC (Cortical Lamination Adjacent to Vascular Malformation)
label: Focal Cortical Dysplasia Type IIIC

FCD Type IIID
type: Class
subclass of: Focal Cortical Dysplasia Type III
subclass of: Class
  intersection of: Restriction
    on property: hasNeuroPathologyFinding
    some values from: CorticalDyslamination
  intersection of: Restriction
    on property: isAdjacentTo
    some values from: Scar
comment: FCD Type IIID (Cortical Lamination Abnormality Adjacent to Any Other Lesion Acquired During Early Life)
label: Focal Cortical Dysplasia Type IIID

FCD Type III
type: Class
subclass of: Focal Cortical Dysplasia Type III
comment: FCD Type III (Not Otherwise Specified, NOS)
label: Focal Cortical Dysplasia Type III NOS
label: Focal Cortical Dysplasia Type III Not Otherwise Specified

Focal Epilepsy
type: Class
subclass of: Epilepsy
subclass of: Restriction
  on property: hasPreferredMedication
  some values from: Carbamazepine

Focal epileptogenic zone
type: Class
subclass of: Epileptogenic Zone

Focal Polyspikes
type: Class
subclass of: PolySpikes

Focal Resection
type: Class
subclass of: Epilepsy Surgery

Focal Seizure
type: Class
subclass of: Paroxysmal Event
subclass of: Restriction
  on property: hasSeizureOnsetZone
  some values from: CerebralHemisphereLobe

Focal Sharp Wave
type: Class
subclass of: Sharp Wave

Focal Spike
type: Class
subclass of: Spike

Focalin
type: Class
subclass of: Drug Brand Name
see also: RxCUI 352654

Foot Segment
type: Class
subclass of: Free Lower Limb Segment

FST
type: Class
subclass of: Model System Depression Scale
label: Forced swim test

Forebrain
type: Class
subclass of: Cardinal Brain Segment
subclass of: Restriction
  on property: regional part of
  some values from: Brain
comment: The most anterior region the brain including both the telencephalon and diencephalon.

Forebrain Neural Tissue
type: Class
subclass of: Brain Neural Tissue Segment
subclass of: Restriction
  on property: regional part of
  some values from: Brain Neural Tissue
comment: Fmaid 268544

Forebrain Segment
type: Class
subclass of: Brain Segment

Forfivo
type: Class
subclass of: Drug Brand Name
see also: RxCUI 1232586

Fosphenytoin
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Cerebyx
    union of: Sesquient
comment: Antiepileptic drug
see also: RxCUI 72236

Fourteen-Six Hertz Positive Burst
type: Class
subclass of: Epileptiform Benign Variant
comment: Fourteen and six-hertz positive bursts consist of short trains of arch-shaped waveforms with alternating postive spiky components and a negative, smooth, rounded waveforms that occur at a rate of 14 Hz or 6-7 Hz and last from 0.5 to 1 second.

Fourth Toe
type: Class
subclass of: Toe

Frameshift
type: Class
subclass of: "Molecular consequence represents effects on protein products from the alterations in the coding nucleotide sequence. " (https://www.ncbi.nlm.nih.gov/variation/docs/glossary/)
label: Frameshift Variant
label: frameshift_variant

Free gamma-aminobutyric acid
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: Neuro Transmitter

Free Limb Segment
type: Class
subclass of: Limb Segment

Free Lower Limb Segment
type: Class
subclass of: Free Limb Segment

Free Upper Limb Segment
type: Class
subclass of: Free Limb Segment
comment: Free upper limb segment (Source: FMA)

Frisium
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 151794
comment: Treats seizures in patients who have Lennox-Gastaut syndrome (LGS). This medicine is a benzodiazepine.

Frontal 10-10 System
type: Class
subclass of: 10-10 System

Frontal
type: Class
subclass of: Anatomical Coordinate

FAR
type: Class
subclass of: Rhythmic Benign Variant
comment: Frontal arousal rhythm (FAR) consists of trains of 7- to 20-Hz waveforms that occur predominantly over the frontal regions in runs lasting up to 20 seconds.
label: Frontal Arousal Rhythm

Frontal intermittent Rhythmic Delta Activity
type: Class
subclass of: Slow Activity
subclass of: Restriction
  on property: isLocatedAt
  some values from: FrontalLobe

FrontalLobe
type: Class
subclass of: CerebralHemisphereLobe
comment: Frontal lobe is the anterior-most of five lobes of the cerebral hemisphere. It is bounded by the central sulcus on its posterior border and by the longitudinal cerebral fissure on its medial border. (FMA)

Frontal Lobe Dorsolateral Zone
type: Class
subclass of: Telencephalon Zone

Frontal Lobe Epilepsy
type: Class
subclass of: Single Focal Epilepsy
subclass of: Restriction
  on property: hasEtiology
  some values from: Class
    union of: Brain Tumor
    union of: Cortical Dysplasia
    union of: Vascular Malformation
subclass of: Restriction
  on property: hasIctalEpileptiformAbnormality
  some values from: EEG-SZ
subclass of: Restriction
  on property: hasInterIctalEpileptiformAbnormality
  some values from: Class
    union of: Sharp Wave
    union of: Spike

Gyrus of frontal lobe
type: Class
subclass of: BrainGyrus

Orbitobasal segment of frontal lobe
type: Class
subclass of: Frontal

Basal Frontal
type: Class
subclass of: Frontal
comment: Orbitofrontal segment of frontal lobe
label: Orbito-Frontal

Frontal
type: Class
subclass of: Segment of cerebral lobe

Frontal Operculum
type: Class
subclass of: Telencephalon Zone
label: Fronto-Opercular

Frontal Pole
type: Class
subclass of: Telencephalon Zone
label: Fronto-Polar

Frontomarginal gyrus
type: Class
subclass of: Gyrus of frontal lobe

Frontocentral N270
type: Class
subclass of: Scalp Recorded ERP Extracted Pattern

Frontocentral P3a
type: Class
subclass of: Scalp Recorded ERP Extracted Pattern

Frontopolar Epilepsy
type: Class
subclass of: Lateral Frontal Epilepsy

Frontotemporal N3
type: Class
subclass of: Scalp Recorded ERP Extracted Pattern

Functional Deficit Zone
type: Class
subclass of: EpilepsyZone
comment: Area of cortex, which by functional neuroimaging, neuropsychological testing, neurologic examination, or other tests shows functional abnormalities.

fMRI
type: Class
subclass of: MR
label: functional magnetic resonance imaging

FunctionalNearInfraredSpectroscopy
type: Class
subclass of: MRS
see also: Functional NIR Spectroscopy
see also: Functional Near-Infrared Spectroscopy

Fusiform gyrus
type: Class
subclass of: TemporalLobeGyrus
label: Lateral occipitotemporal gyrus
label: Medial occipitotemporal gyrus-1 (Heimer)
label: Occipitotemporal gyrus

gamma-aminobutyric acid (GABA) A receptor, alpha 1
type: Class
subclass of: Gene

gamma-aminobutyric acid type A receptor subunit beta3
type: Class
subclass of: Gene

gamma-aminobutyric acid (GABA) A receptor, delta
type: Class
subclass of: Gene

gamma-aminobutyric acid (GABA) A receptor, gamma 2
type: Class
subclass of: Gene
subclass of: Restriction
  on property: hasSequenceVariant
  all values from: Allele ID: 75270

galanin and GMAP prepropeptide
type: Class
subclass of: Gene

polypeptide N-acetylgalactosaminyltransferase 3
type: Class
subclass of: Gene

glycine decarboxylase
type: Class
subclass of: Gene

GLI family zinc finger 3
type: Class
subclass of: Gene

golgi SNAP receptor complex member 2
type: Class
subclass of: Gene

glutamate ionotropic receptor NMDA type subunit 1
type: Class
subclass of: Gene

glutamate ionotropic receptor NMDA type subunit 2A
type: Class
subclass of: Gene
subclass of: Restriction
  on property: hasSequenceVariant
  some values from: Class
    union of: Allele ID: 94304
    union of: Allele ID: 94305
    union of: Allele ID: 94306
    union of: Allele ID: 94309
    union of: Allele ID: 94310
    union of: Allele ID: 94311

glutamate ionotropic receptor NMDA type subunit 2B
type: Class
subclass of: Gene

Gabapentin
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Fanatrex
    union of: Gabarone
    union of: Gralise
    union of: Horizant
    union of: Neurontin®
comment: Anti seizure medication
comment: Antiepileptic Drug
is defined by: Treats certain types of seizures, called partial seizures, in people who have epilepsy. Also treats Restless Legs Syndrome (RLS) and pain caused by shingles (postherpetic neuralgia).
see also: RxCUI 25480

Gabarone
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 602396

Gabitril®
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 217243
comment: Controls partial seizures when used in combination with other medicines. This medicine is an anticonvulsant.

Gamma-aminobutyric acid
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: Neuro Transmitter

GABA
type: Class
subclass of: Biological Substance
subclass of: Class
  union of: GABA B Receptor
  union of: Restriction
    on property: hasBindingTo
    some values from: GABA A Receptor
subclass of: Restriction
  on property: hasFunction
  some values from: Protein
label: Gamma Amino Butyric Acid

Ganaxolone
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Ztalmy
see also: RxCUI 2604689

GG
type: Class
subclass of: Brain Glial Neuronal Tumor
subclass of: Restriction
  on property: WHO grading
  some values from: WHO grade I
subclass of: Restriction
  on property: hasAssociatedMutationIn
  all values from: B-Raf proto-oncogene
label: Gangliocytoma

Gelastic Episode
type: Class
subclass of: Complex Motor Episode

Gelastic Seizure
type: Class
subclass of: Complex Motor Seizure
comment: Cognitive (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Gelastic seizures are complex motor seizures that include laughing as the essential "complex motor activity".

Gelastic Status
type: Class
subclass of: Complex Motor Status
comment: Aware (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Gender
type: Class
subclass of: Organism Phenotype
comment: CURE CDE (WG #1: Core and Death-Related Information)
label: Sex

Gene Attribute
type: Class
subclass of: Independent Continuant

General Learning Disability
type: Class
subclass of: Disorder
label: Mental Retardation

Generalized Epilepsy
type: Class
subclass of: Epilepsy

GEFS+
type: Class
subclass of: Generalized Epilepsy
subclass of: Restriction
  on property: hasAgeOfOnset
  some values from: Infant
subclass of: Restriction
  on property: hasAssociatedMutationIn
  some values from: Class
    union of: gamma-aminobutyric acid (GABA) A receptor, delta
    union of: gamma-aminobutyric acid (GABA) A receptor, gamma 2
    union of: sodium channel, voltage-gated, type I, alpha subunit
    union of: sodium channel, voltage-gated, type I, beta subunit
    union of: sodium channel, voltage-gated, type II, alpha subunit
subclass of: Restriction
  on property: hasEtiology
  some values from: Class
    union of: Genetic Mutation
    union of: Unknown Cause
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: Class
    union of: Dialeptic Seizure
    union of: Simple Motor Seizure
label: Generalized Epilepsy With Febrile Seizures Plus

Generalized epileptogenic zone
type: Class
subclass of: Epileptogenic Zone

Focal to bilateral tonic-clonic
type: Class
subclass of: ConvulsiveMotorSeizure

Generalized Paroxysmal Fast Activity
type: Class
subclass of: Inter Ictal Pattern

Generalized Polyspike
type: Class
subclass of: Spike

Generalized Polyspikes
type: Class
subclass of: PolySpikes

Generalized Seizure
type: Class
subclass of: Paroxysmal Event

Generalized Sharp Wave
type: Class
subclass of: Sharp Wave

Genetic Background
type: Class
subclass of: Organism Genotype
comment: CURE CDE (WG #1: Core and Death-Related Information)

Genetic Defect
type: Class
subclass of: Aetiology

Genetic Mutation
type: Class
subclass of: Genetic Defect

Genomic Variation
type: Class
subclass of: Independent Continuant
comment: Based on the NCBI ClinVar genomic variation data resource with sequence variation, type of variation, and variant consequence information

Geodon
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 285064

Glial Cell
type: Class
subclass of: Neural Cell

GFAP
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: isUsedForMarkingCellularPattern
  some values from: Astrocytus
label: Glial Fibrillary Acidic Protein
label: http://purl.bioontology.org/ontology/SNOMEDCT/24675006

GBM
type: Class
subclass of: Astrocytic
subclass of: Restriction
  on property: hasAssociatedMutationIn
  some values from: Class
    union of: Isocitrate Dehydrogenase (NADP(+)) 1
    union of: Isocitrate Dehydrogenase (NADP(+)) 2
subclass of: Restriction
  on property: WHO grading
  some values from: WHO_IV
label: Glioblastoma Multiforme

Gliosis
type: Class
subclass of: Astrogliosis
subclass of: Restriction
  on property: hasValue
  qualified cardinality: 1
  on data range: integer

Gliosis without hippocampal sclerosis
type: Class
subclass of: Hippocampal sclerosis
subclass of: Restriction
  on property: hasAstrogliosisValue
  some values from: Class
    union of: Class
      intersection of: Gliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA1
    union of: Class
      intersection of: Moderate Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA1
subclass of: Restriction
  on property: hasAstrogliosisValue
  some values from: Class
    union of: Class
      intersection of: Gliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA2
    union of: Class
      intersection of: Moderate Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA2
subclass of: Restriction
  on property: hasAstrogliosisValue
  some values from: Class
    union of: Class
      intersection of: Gliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA3
    union of: Class
      intersection of: Moderate Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA3
subclass of: Restriction
  on property: hasAstrogliosisValue
  some values from: Class
    union of: Class
      intersection of: Gliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA4
    union of: Class
      intersection of: Moderate Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA4
subclass of: Restriction
  on property: hasAstrogliosisValue
  some values from: Class
    union of: Class
      intersection of: Gliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Area dentata
    union of: Class
      intersection of: Moderate Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Area dentata
subclass of: Restriction
  on property: hasAstrogliosisValue
  some values from: Class
    union of: Class
      intersection of: Gliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Subiculum hippocampi
    union of: Class
      intersection of: Moderate Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Subiculum hippocampi
subclass of: Restriction
  on property: hasNeuronalLossValue
  some values from: Class
    union of: Class
      intersection of: GFAP
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA1
    union of: Class
      intersection of: No neuronal loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA1
subclass of: Restriction
  on property: hasNeuronalLossValue
  some values from: Class
    union of: Class
      intersection of: GFAP
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA2
    union of: Class
      intersection of: No neuronal loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA2
subclass of: Restriction
  on property: hasNeuronalLossValue
  some values from: Class
    union of: Class
      intersection of: GFAP
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA3
    union of: Class
      intersection of: No neuronal loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA3
subclass of: Restriction
  on property: hasNeuronalLossValue
  some values from: Class
    union of: Class
      intersection of: GFAP
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA4
    union of: Class
      intersection of: No neuronal loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA4
subclass of: Restriction
  on property: hasNeuronalLossValue
  some values from: Class
    union of: Class
      intersection of: GFAP
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Area dentata
    union of: Class
      intersection of: No neuronal loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Area dentata
subclass of: Restriction
  on property: hasNeuronalLossValue
  some values from: Class
    union of: Class
      intersection of: GFAP
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Subiculum hippocampi
    union of: Class
      intersection of: No neuronal loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Subiculum hippocampi

GAD65
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: Neurotransmitter synthesis
label: Glutamate Decarboxylase 65

GAD65AssociatedEncephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
subclass of: Restriction
  on property: hasAssociatedAntigen
  some values from: GAD65
label: Glutamate Decarboxylase 65 Associated Encephalitis

Glutamic acid
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: Neuro Transmitter

Glutamic Acid Hydrochloride
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: Neuro Transmitter

glycine receptor protein
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: Neurotransmitter receptor

GlyRAssociatedEncephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
subclass of: Restriction
  on property: hasAssociatedAntigen
  some values from: glycine receptor protein
label: Glycine Receptor Associated Encephalitis

Golgi Complex
type: Class
subclass of: Sub Cellular Structure

Gracile Tubercle
type: Class
subclass of: Medulla Oblongata

Gralise
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 1087976

Granular Leukocyte
type: Class
subclass of: Immune cell

Granule Cell
type: Class
subclass of: Neuron

Gustatory Aura
type: Class
subclass of: Non-Specific Aura
comment: It used to denote a type of aura that manifests itself in the form of a gustatory hallucination or illusion.
comment: Sensory (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Gustatory Aura Status
type: Class
subclass of: Aura status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

H3.3 histone A
type: Class
subclass of: Gene

hyperpolarization activated cyclic nucleotide gated potassium channel 1
type: Class
subclass of: Gene

ClassicalSeverePatternsHippocampalSclerosis
type: Class
subclass of: Hippocampal sclerosis
subclass of: Restriction
  on property: hasAstrogliosisValue
  some values from: Class
    intersection of: Fibrillary Astrogliosis
    intersection of: Restriction
      on property: isLocatedAt
      all values from: CA1
subclass of: Restriction
  on property: hasAstrogliosisValue
  some values from: Class
    intersection of: Fibrillary Astrogliosis
    intersection of: Restriction
      on property: isLocatedAt
      all values from: CA4
subclass of: Restriction
  on property: hasAstrogliosisValue
  some values from: Class
    union of: Class
      intersection of: Fibrillary Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA2
    union of: Class
      intersection of: Gliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA2
    union of: Class
      intersection of: Moderate Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA2
subclass of: Restriction
  on property: hasAstrogliosisValue
  some values from: Class
    union of: Class
      intersection of: Fibrillary Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA3
    union of: Class
      intersection of: Gliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA3
    union of: Class
      intersection of: Moderate Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA3
subclass of: Restriction
  on property: hasAstrogliosisValue
  some values from: Class
    union of: Class
      intersection of: Fibrillary Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Area dentata
    union of: Class
      intersection of: Gliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Area dentata
    union of: Class
      intersection of: Moderate Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Area dentata
subclass of: Restriction
  on property: hasAstrogliosisValue
  some values from: Class
    union of: Class
      intersection of: Gliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Subiculum hippocampi
    union of: Class
      intersection of: Moderate Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Subiculum hippocampi
subclass of: Restriction
  on property: hasNeuronalLossValue
  some values from: Class
    intersection of: Severe Neuronal Loss
    intersection of: Restriction
      on property: isLocatedAt
      all values from: CA1
subclass of: Restriction
  on property: hasNeuronalLossValue
  some values from: Class
    intersection of: Severe Neuronal Loss
    intersection of: Restriction
      on property: isLocatedAt
      all values from: CA4
subclass of: Restriction
  on property: hasNeuronalLossValue
  some values from: Class
    union of: Class
      intersection of: GFAP
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA2
    union of: Class
      intersection of: No neuronal loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA2
    union of: Class
      intersection of: Severe Neuronal Loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA2
subclass of: Restriction
  on property: hasNeuronalLossValue
  some values from: Class
    union of: Class
      intersection of: GFAP
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA3
    union of: Class
      intersection of: No neuronal loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA3
    union of: Class
      intersection of: Severe Neuronal Loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA3
subclass of: Restriction
  on property: hasNeuronalLossValue
  some values from: Class
    union of: Class
      intersection of: GFAP
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Area dentata
    union of: Class
      intersection of: No neuronal loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Area dentata
    union of: Class
      intersection of: Severe Neuronal Loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Area dentata
subclass of: Restriction
  on property: hasNeuronalLossValue
  some values from: Class
    union of: Class
      intersection of: GFAP
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Subiculum hippocampi
    union of: Class
      intersection of: No neuronal loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Subiculum hippocampi
label: HSILAEType1

CA1Sclerosis
type: Class
subclass of: Hippocampal sclerosis
subclass of: Restriction
  on property: hasAstrogliosisValue
  some values from: Class
    union of: Class
      intersection of: Fibrillary Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA1
    union of: Class
      intersection of: Moderate Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA1
subclass of: Restriction
  on property: hasAstrogliosisValue
  some values from: Class
    union of: Class
      intersection of: Gliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA2
    union of: Class
      intersection of: Moderate Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA2
subclass of: Restriction
  on property: hasAstrogliosisValue
  some values from: Class
    union of: Class
      intersection of: Gliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA3
    union of: Class
      intersection of: Moderate Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA3
subclass of: Restriction
  on property: hasAstrogliosisValue
  some values from: Class
    union of: Class
      intersection of: Gliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA4
    union of: Class
      intersection of: Moderate Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA4
subclass of: Restriction
  on property: hasAstrogliosisValue
  some values from: Class
    union of: Class
      intersection of: Gliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Area dentata
    union of: Class
      intersection of: Moderate Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Area dentata
subclass of: Restriction
  on property: hasAstrogliosisValue
  some values from: Class
    union of: Class
      intersection of: Gliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Subiculum hippocampi
    union of: Class
      intersection of: Moderate Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Subiculum hippocampi
subclass of: Restriction
  on property: hasNeuronalLossValue
  some values from: Class
    union of: Class
      intersection of: GFAP
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA1
    union of: Class
      intersection of: Severe Neuronal Loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA1
subclass of: Restriction
  on property: hasNeuronalLossValue
  some values from: Class
    union of: Class
      intersection of: GFAP
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA2
    union of: Class
      intersection of: No neuronal loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA2
subclass of: Restriction
  on property: hasNeuronalLossValue
  some values from: Class
    union of: Class
      intersection of: GFAP
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA3
    union of: Class
      intersection of: No neuronal loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA3
subclass of: Restriction
  on property: hasNeuronalLossValue
  some values from: Class
    union of: Class
      intersection of: GFAP
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA4
    union of: Class
      intersection of: No neuronal loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA4
subclass of: Restriction
  on property: hasNeuronalLossValue
  some values from: Class
    union of: Class
      intersection of: GFAP
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Area dentata
    union of: Class
      intersection of: No neuronal loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Area dentata
subclass of: Restriction
  on property: hasNeuronalLossValue
  some values from: Class
    union of: Class
      intersection of: GFAP
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Subiculum hippocampi
    union of: Class
      intersection of: No neuronal loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Subiculum hippocampi
label: HSILAEType2

CA4Sclerosis
type: Class
subclass of: Hippocampal sclerosis
subclass of: Restriction
  on property: hasAstrogliosisValue
  some values from: Class
    union of: Class
      intersection of: Fibrillary Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA3
    union of: Class
      intersection of: Gliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA3
    union of: Class
      intersection of: Moderate Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA3
subclass of: Restriction
  on property: hasAstrogliosisValue
  some values from: Class
    union of: Class
      intersection of: Fibrillary Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA4
    union of: Class
      intersection of: Moderate Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA4
subclass of: Restriction
  on property: hasAstrogliosisValue
  some values from: Class
    union of: Class
      intersection of: Fibrillary Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Area dentata
    union of: Class
      intersection of: Gliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Area dentata
    union of: Class
      intersection of: Moderate Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Area dentata
subclass of: Restriction
  on property: hasAstrogliosisValue
  some values from: Class
    union of: Class
      intersection of: Gliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA1
    union of: Class
      intersection of: Moderate Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA1
subclass of: Restriction
  on property: hasAstrogliosisValue
  some values from: Class
    union of: Class
      intersection of: Gliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA2
    union of: Class
      intersection of: Moderate Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA2
subclass of: Restriction
  on property: hasAstrogliosisValue
  some values from: Class
    union of: Class
      intersection of: Gliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Subiculum hippocampi
    union of: Class
      intersection of: Moderate Astrogliosis
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Subiculum hippocampi
subclass of: Restriction
  on property: hasNeuronalLossValue
  some values from: Class
    union of: Class
      intersection of: GFAP
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA1
    union of: Class
      intersection of: No neuronal loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA1
subclass of: Restriction
  on property: hasNeuronalLossValue
  some values from: Class
    union of: Class
      intersection of: GFAP
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA2
    union of: Class
      intersection of: No neuronal loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA2
subclass of: Restriction
  on property: hasNeuronalLossValue
  some values from: Class
    union of: Class
      intersection of: GFAP
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA3
    union of: Class
      intersection of: No neuronal loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA3
    union of: Class
      intersection of: Severe Neuronal Loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA3
subclass of: Restriction
  on property: hasNeuronalLossValue
  some values from: Class
    union of: Class
      intersection of: GFAP
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA4
    union of: Class
      intersection of: Severe Neuronal Loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: CA4
subclass of: Restriction
  on property: hasNeuronalLossValue
  some values from: Class
    union of: Class
      intersection of: GFAP
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Area dentata
    union of: Class
      intersection of: No neuronal loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Area dentata
    union of: Class
      intersection of: Severe Neuronal Loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Area dentata
subclass of: Restriction
  on property: hasNeuronalLossValue
  some values from: Class
    union of: Class
      intersection of: GFAP
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Subiculum hippocampi
    union of: Class
      intersection of: No neuronal loss
      intersection of: Restriction
        on property: isLocatedAt
        all values from: Subiculum hippocampi
label: EndfoliumSclerosis
label: HSILAEType3

Habenula
type: Class
subclass of: Diencephalon Zone
comment: Habenula is a segment of the epithalamus that has as its parts the lateral and medial habenular nuclei and the habenular commissure.

Habenular Trigone
type: Class
subclass of: Diencephalon Zone
comment: The habenular trigone is a small depressed triangular area situated in front of the superior colliculus and on the lateral aspect of the posterior part of the taenia thalami. It contains a group of nerve cells termed the ganglion habenulC&. Fibers enter it from the stalk of the pineal body, and others, forming what is termed the habenular commissure, pass across the middle line to the corresponding ganglion of the opposite side. Most of its fibers are, however, directed downward and form a bundle, the fasciculus retroflexus of Meynert, which passes medial to the red nucleus, and, after decussating with the corresponding fasciculus of the opposite side, ends in the interpeduncular ganglion

Habitual Seizure Type
type: Class
subclass of: Clinical Finding
subclass of: Restriction
  on property: isManifestedBy
  some values from: Epileptic Seizure

Haematopoietic Cell
type: Class
subclass of: Cell

Haldol
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 151839

Haloperidol
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Haldol
comment: Antidepressant Drug
is defined by: Treats mental illness (such as schizophrenia), behavior problems, agitation, and symptoms of Tourette's syndrome.
see also: RxCUI 5093

Hand Segment
type: Class
subclass of: Free Upper Limb Segment
comment: Segment of hand (source: FMA)

Haponal
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 217492

Head
type: Class
subclass of: Cardinal Body Part
comment: Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the skull, it is partially surrounded by skin of head. Examples: There is only one head. (source: FMA)

Head Region 10-10 System
type: Class
subclass of: 10-10 System

Subdivision of Head
type: Class
subclass of: Cardinal Body Part Subdivision

Heart Myocyte
type: Class
subclass of: MuscleCell

Heart Rate
type: Class
subclass of: Physiological Data
comment: CURE CDE (WG #1: Core and Death-Related Information)

Hemi Clonic Episode
type: Class
subclass of: Simple Motor Episode

ConvulsiveMotorSeizure
type: Class
subclass of: Simple Motor Seizure
comment: Clonic (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Generalized Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Motor seizures characterized by rhythmic or semi-rhythmic jerking of half the body.
comment: Unknown Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
label: Hemiclonic Seizure
label: Hemiconvulsive seizure

Hemi Clonic Status
type: Class
subclass of: SimpleMotorStatus
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Motor Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Hemiconvulsion Hemiplegia Epilepsy
type: Class
subclass of: Multi Focal Epilepsy
label: Hemiconvulsion-hemiplegia-epilepsy

Hemisphere 10-10 System
type: Class
subclass of: 10-10 System

Hemisphere
type: Class
subclass of: Focal epileptogenic zone
subclass of: Restriction
  on property: isLocatedAt
  some values from: Class
    union of: Left Cerebral Hemisphere
    union of: Right Cerebral Hemisphere
label: Hemispheric Epileptogenic Zone

Heterogeneous Cluster
type: Class
subclass of: Anatomical Cluster
comment: Anatomical cluster which has as its direct parts all or some members of two or more organ subclasses and one or more organ part subclasses which are grouped together according to some shared attributes. Examples: joint, internal ear, pharynx. (source: FMA)

High Frequency Oscillation
type: Class
subclass of: Intra Cranial EEG Data

Hind Limb Extension
type: Class
subclass of: Posture At Death
subclass of: Restriction
  on property: occursIn
  some values from: Rodent

Hippocampal Cell Culture
type: Class
subclass of: Cell Culture

Hippocampal Epilepsy
type: Class
subclass of: Temporal Lobe Epilepsy
subclass of: Restriction
  on property: hasEtiology
  some values from: Hippocampal Sclerosis
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: Abdominal Aura

Hippocampal Formation
type: Class
subclass of: Telencephalon Zone

Hippocampal sclerosis
type: Class
subclass of: Sclerosis
subclass of: Restriction
  on property: hasNeuronalLossValue
  some values from: Neuronal Loss

Hippocampal Slice
type: Class
subclass of: Slice

Hippocampal
type: Class
subclass of: LimbicLobeGyrus

Segment of hippocampus proper
type: Class
subclass of: Segment of hippocampus

Segment of hippocampus
type: Class
subclass of: Segment of gyrus of limbic lobe

Horizant
type: Class
subclass of: Drug Brand Name
synonym: RxCU I095698

Horizontal
type: Class
subclass of: Anatomical Coordinate

Human
type: Class
subclass of: Independent Continuant
label: Human Being

Human Body Part
type: Class
subclass of: Bodily Feature

Human Measurement Method
type: Class
subclass of: Measurement Method

Hyosophen
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 217656

Hypehydrotic Seizure
type: Class
subclass of: Autonomic Seizure

Hyperkinesis with developmental delay
type: Class
subclass of: ADHD

Hyperkinetic conduct disorder
type: Class
subclass of: ADHD

Hypermotor Episode
type: Class
subclass of: Complex Motor Episode

Hypermotor Seizure
type: Class
subclass of: Complex Motor Seizure
comment: Hyperkinetic (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Hypermotor seizures are complex motor seizures in which movements affect primarily proximal body segments resulting in high amplitude, rapid movements such as cycling movements.

Hypermotor Status
type: Class
subclass of: Complex Motor Status
comment: Hyperkinetic status epilepticus (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Hypertensive Spontaneous Intracerebral Hemorrhage
type: Class
subclass of: Intracerebral Hemorrhage

Fever induced seizure
type: Class
subclass of: Temperature Induced Seizure
label: Hyperthermia Induced Seizure

Hyperventilation Response
type: Class
subclass of: Activation Procedure
comment: Hyperventilation response is a method used to cause rapid, deep breathing; this technique produces generalized slowing of the EEG and may provoke epileptiform waves or seizures (especially absences seizures) during an EEG recording.

Hypnogogic Episode
type: Class
subclass of: Special Episode

Hypnogogic seizure
type: Class
subclass of: Special Seizure
comment: Generalized Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Motor (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Myoclonic (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Unknown Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Hypnogogic Status
type: Class
subclass of: Special Status

Hypnopompic Episode
type: Class
subclass of: Special Episode

Hypnopompic Seizure
type: Class
subclass of: Special Seizure

Hypnopompic Status
type: Class
subclass of: Special Status

Hypomotor Episode
type: Class
subclass of: Special Episode

Hypomotor Seizure
type: Class
subclass of: Special Seizure
comment: Hypomotor seizures are characterized by immobility or a marked decrease in movements of newborns, infants or of mentally retarded patients in whom the cause of the immobility (alteration of consciousness, inability to move distraction by an aura, etc.) cannot be determined.

Hypomotor Status
type: Class
subclass of: Special Status

Hypopnea Syndrome
type: Class
subclass of: Sleep disorder

Hypothalamic Epilepsy
type: Class
subclass of: Single Focal Epilepsy
subclass of: Restriction
  on property: hasAssociatedDisorder
  some values from: Class
    union of: Mental Retardation
    union of: Precocious Puberty
subclass of: Restriction
  on property: hasAssociatedMutationIn
  some values from: GLI family zinc finger 3
subclass of: Restriction
  on property: hasEtiology
  some values from: Hypothalamic Hamartoma
subclass of: Restriction
  on property: hasIctalEpileptiformAbnormality
  some values from: EEG-SZ
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: Gelastic Seizure

Hypothalamic Hamartoma
type: Class
subclass of: Hamartoma
subclass of: Restriction
  on property: hasAssociatedMutationIn
  some values from: GLI family zinc finger 3

Hypothalamus Zone
type: Class
subclass of: Diencephalon Zone
comment: A regional part of brain that is part of a hypothalamus

Hypoxic Ischemic Injury
type: Class
subclass of: Structural Cause

Hypsarrhythmia
type: Class
subclass of: Inter Ictal Pattern
comment: Hypsarrhythmia (HYP) refers to the pattern characterized by generalized continuous slow activity with an amplitude higher than 300 uV and the appearance of multiregional spikes or sharp waves over both hemispheres.

Isocitrate Dehydrogenase (NADP(+)) 1
type: Class
subclass of: Gene

Isocitrate Dehydrogenase (NADP(+)) 2
type: Class
subclass of: Gene

immediate early response 3 interacting protein 1
type: Class
subclass of: Gene

Ictal Apnea
type: Class
subclass of: Induced apnea

Dystonic Posturing
type: Class
subclass of: Lateralizing Sign
subclass of: Restriction
  on property: isLocatedAt
  some values from: Class
    union of: Left Hand
    union of: Right Hand
subclass of: Restriction
  on property: occursAt
  some values from: Ictal
comment: Ictal dystonia is abnormal muscle tone, rsulting in muscle spasms and abnormal postures, during episode of seizure.
label: Ictal Dystonia

Ictal Nystagmus
type: Class
subclass of: Lateralizing Sign

Ictal Pattern
type: Class
subclass of: Epileptiform Pattern

Ictal Speech
type: Class
subclass of: Lateralizing Sign
comment: Ictal speech is abnormal speech production during episode of seizure.

Iloperidone
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Fanapt
comment: Antidepressant Drug
see also: RxCUI 73178

Imaging Modality
type: Class
subclass of: Nervous System Measurement Modality

Imipramine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Class
    intersection of: Imipramine Hydrochloride
    intersection of: Imipramine Pamoate
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Tofranil
    union of: Tofranil-PM
comment: Neuroleptic Drug
see also: RxCUI 5691

Imipramine Hydrochloride
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 150816

Imipramine Pamoate
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 91118

Immaterial Anatomical Entity
type: Class
subclass of: Human Body Part
comment: Physical anatomical entity which is a three-dimensional space, surface, line or point associated with a material anatomical entity. Examples: body space, surface of heart, costal margin, apex of right lung, anterior compartment of right arm. (source: FMA)

Immature Microglial Cell
type: Class
subclass of: Hortega cell
label: Immature microglia
label: Quiescent microglia
label: Resting microglia

Immature Schwann Cell
type: Class
subclass of: Schwann cell

Inapsine
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 202603

Increased Asymmetry Pattern
type: Class
subclass of: Asymmetry Pattern

Indel
type: Class
subclass of: Variation Type
label: Indel Variant

Index Finger
type: Class
subclass of: Finger

Induced apnea
type: Class
subclass of: Apnea

Induced Pluripotent Stem Cells
type: Class
subclass of: Cell Culture
label: iPSC

Infant
type: Class
subclass of: Human
subclass of: Restriction
  on property: hasRecordedAge
  min qualified cardinality: 2
  on class: Month
subclass of: Restriction
  on property: hasRecordedAge
  max qualified cardinality: 1
  on class: Year
comment: the human young from the time of birth to one year of age

Inferior frontal convolution
type: Class
subclass of: Gyrus of frontal lobe

Inferior temporal gyrus
type: Class
subclass of: TemporalLobeGyrus
label: Lateral occipitotemporal gyrus (Heimer-83)

Inframe Deletion
type: Class
subclass of: "Molecular consequence represents effects on protein products from the alterations in the coding nucleotide sequence. " (https://www.ncbi.nlm.nih.gov/variation/docs/glossary/)
label: Inframe Deletion Variant
label: http://www.sequenceontology.org/browser/current_svn/term/SO:0001822
label: inframe_deletion

Inframe Indel
type: Class
subclass of: "Molecular consequence represents effects on protein products from the alterations in the coding nucleotide sequence. " (https://www.ncbi.nlm.nih.gov/variation/docs/glossary/)
label: Inframe Indel Variant
label: inframe_indel

Inframe Insertion
type: Class
subclass of: "Molecular consequence represents effects on protein products from the alterations in the coding nucleotide sequence. " (https://www.ncbi.nlm.nih.gov/variation/docs/glossary/)
label: Inframe Insertion Variant
label: inframe_insertion

Inion
type: Class
subclass of: Anatomical midline point of skull
comment: "The projecting part of the occipital bone at the base of the skull." (Foundational Model of Anatomy)

Innumerable
type: Class
subclass of: Seizure Frequency Category
subclass of: Restriction
  on property: hasValue
  some values from: Datatype
    on datatype: integer
    with restrictions:
      min inclusive: 10
comment: American Academy of Neurology recommended seizure frequency category.
comment: LA32852-8 (LOINC Code)
label: Innumerable Seizure

Inovelon®
type: Class
subclass of: Drug Brand Name
comment: Treats seizures in patients who have Lennox-Gastaut syndrome (LGS).

Insertion
type: Class
subclass of: Variation Type
label: Insertion Variant

Insular
type: Class
subclass of: CerebralHemisphereLobe
comment: Lobe of cerebral hemispheere located in the depths of the lateral fissure and is covered by portions of the frontal, parietal and temporal lobes.

Anterior lobule of insula
type: Class
subclass of: Lobule of insula

Lobule of insula
type: Class
subclass of: Segment of cerebral lobe

Posterior lobule of insula
type: Class
subclass of: Lobule of insula

Insular Epilepsy
type: Class
subclass of: Single Focal Epilepsy
subclass of: Restriction
  on property: hasEtiology
  some values from: Class
    union of: DNET
    union of: Glioma
subclass of: Restriction
  on property: hasIctalEpileptiformAbnormality
  some values from: EEG-SZ
subclass of: Restriction
  on property: hasInterIctalEpileptiformAbnormality
  some values from: Class
    union of: Sharp Wave
    union of: Spike
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: Somatosensory Aura

Inter Ictal
type: Class
subclass of: Electroencephalogram Finding

Inter Ictal Pattern
type: Class
subclass of: Epileptiform Pattern

Intergeniculate Leaf
type: Class
subclass of: Diencephalon Zone

Intermediate
type: Class
subclass of: Anatomical Coordinate

Intermediate Hypothalamic Region
type: Class
subclass of: Hypothalamus Zone
comment: Brain structure that lies perpendicular to the longitudinal axis of the embryonic neural tube, is continuous with the rostral hypothalamic proliferation and whose most lateral extent is deflected dorsally within the inferior lobe

Intermediate orbital gyrus
type: Class
subclass of: Gyrus of frontal lobe

Intermittent Photic Stimulation Response
type: Class
subclass of: Activation Procedure

Intermittent Slow
type: Class
subclass of: Slow Activity
comment: Continuous slow (CS) refers to the activity that occurs continuously (>80% of the time), is non-responsive to external stimuli, and clearly exceeds the amount considered physiologically normal for the patient's age.

End of Intermittent Slow
type: Class
subclass of: Intermittent Slow

Onset of Intermittent Slow
type: Class
subclass of: Intermittent Slow

Internal Gray Matter Component
type: Class
subclass of: Gray Matter of Neuraxis
comment: Gray matter component of neuraxis which is located in the interior of the neuraxis. Example: thalamus, dentate nucleus, ventral horn of spinal cord. (source: FMA)

Intra Cranial EEG Data
type: Class
subclass of: Intra Cranial ERP Data

Intra Cranial ERP Data
type: Class
subclass of: Averaged EEG Data

Intracerebral Hemorrhage
type: Class
subclass of: Cerebral Hemorrhage

Intracranial Electrode
type: Class
subclass of: Electrode

Invega
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 686438

Ion Channel
type: Class
subclass of: Protein Function
comment: "A transmembrane pore that presents a hydrophilic channel for ions to cross a lipid bilayer down their electrochemical gradients. Some degree of ion specificity is usually observed and typically a million ions per second may flow. Channels may be permanently open, like the potassium leak channel or they may be voltage gated, like the sodium channel or ligand gated like the acetylcholine receptor." (National Cancer Institute Thesaurus)

Ionotropic Glutamate Receptor
type: Class
subclass of: Biological Substance

Unilateral Eye Blinking
type: Class
subclass of: Lateralizing Sign
subclass of: Restriction
  on property: isLocatedAt
  some values from: Eye
comment: Unilateral ictal blinking is eye blinking occuring only on one side during episode of seizure.

Irritative Zone
type: Class
subclass of: EpilepsyZone
comment: Area of cortex that produces interictal spikes in the EEG.

Isocarboxazid
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Marplan
comment: Neuroleptic Drug
see also: RxCUI 6011

IDH
type: Class
subclass of: Biological Substance
label: Isocitrate Dehydrogenase
label: R132H
see also: N Engl J Med. 2009 Sep 10;361(11); 1058-66

Isolated heterotropic neurons
type: Class
subclass of: Heterotopia

IA
type: Class
subclass of: Other Glioma
subclass of: Restriction
  on property: WHO grading
  some values from: WHO grade I
label: Isomorphic Astrocytoma

IDG
type: Class
subclass of: Glioma
subclass of: Restriction
  on property: hasAssociatedMutationIn
  some values from: MYB proto-oncogene like 1
label: Isomorphic diffuse glioma

Jamais Vu
type: Class
subclass of: Psychic Aura

JamaisVuStatus
type: Class
subclass of: Pyschic Aura Status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Jamais Vu Status
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Jittery phase
type: Class
subclass of: Physiological pathological process
comment: Part of the Generalized Tonic Clonic Seizure progression (Henri Gastaut)
label: Vibratory phase

End of Jittery Phase
type: Class
subclass of: Jittery phase

Onset of Jittery Phase
type: Class
subclass of: Jittery phase

Juvenile Absence Epilepsy
type: Class
subclass of: Generalized Epilepsy
subclass of: Restriction
  on property: hasAssociatedMutationIn
  some values from: calcium channel, voltage-dependent, T type, alpha 1H subunit
subclass of: Restriction
  on property: hasEtiology
  some values from: Genetic Mutation
subclass of: Restriction
  on property: hasIctalEpileptiformAbnormality
  some values from: Class
    union of: PolySpikes
    union of: Spike
subclass of: Restriction
  on property: hasInterIctalEpileptiformAbnormality
  some values from: Slow Spike and Wave Complex
subclass of: Restriction
  on property: hasPreferredMedication
  some values from: Class
    union of: Ethosuximide
    union of: Valproate
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: Class
    union of: Automotor Seizure
    union of: Dialeptic Seizure
    union of: ConvulsiveMotorSeizure
subclass of: Restriction
  on property: hasAgeOfOnset
  min qualified cardinality: 8
  on class: Year
subclass of: Restriction
  on property: hasAgeOfOnset
  max qualified cardinality: 16
  on class: Year

Juvenile Myoclonic Epilepsy
type: Class
subclass of: Generalized Epilepsy
subclass of: Restriction
  on property: hasAssociatedMutationIn
  some values from: Class
    union of: calcium channel, voltage-dependent, beta 4 subunit
    union of: chloride channel, voltage-sensitive 2
    union of: EF-hand domain (C-terminal) containing 1
    union of: gamma-aminobutyric acid (GABA) A receptor, alpha 1
    union of: gamma-aminobutyric acid (GABA) A receptor, delta
subclass of: Restriction
  on property: hasEtiology
  some values from: Genetic Mutation
subclass of: Restriction
  on property: hasIctalEpileptiformAbnormality
  some values from: EEG-SZ
subclass of: Restriction
  on property: hasInterIctalEpileptiformAbnormality
  some values from: Class
    union of: PolySpikes
    union of: Spike
subclass of: Restriction
  on property: hasPreferredMedication
  some values from: Class
    union of: Lamotrigine
    union of: Levetiracetam
    union of: Topiramate
    union of: Valproate
    union of: Zonisamide
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: Class
    union of: Dialeptic Seizure
    union of: ConvulsiveMotorSeizure
subclass of: Restriction
  on property: hasAgeOfOnset
  min qualified cardinality: 8
  on class: Year
subclass of: Restriction
  on property: hasAgeOfOnset
  max qualified cardinality: 20
  on class: Year

potassium two pore domain channel subfamily K member 4
type: Class
subclass of: Gene

potassium calcium-activated channel subfamily M alpha 1
type: Class
subclass of: Gene

potassium voltage-gated channel subfamily Q member 2
type: Class
subclass of: Gene

potassium voltage-gated channel subfamily Q member 3
type: Class
subclass of: Gene

potassium sodium-activated channel subfamily T member 1
type: Class
subclass of: Gene

potassium channel tetramerization domain containing 7
type: Class
subclass of: Gene

Kruppel like factor 13
type: Class
subclass of: Gene

Keppra®
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 261547
comment: Used to help control certain types of seizures caused by epilepsy. This medicine is an antiepileptic.

Keppra XR™
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 827207
comment: Used to help control certain types of seizures caused by epilepsy. This medicine is an antiepileptic.

Ketogenic diet
type: Class
subclass of: Metabolic Therapy

Ki-67
type: Class
subclass of: Biological Substance
label: Ki-67 Antigen

Klonopin
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 202585
comment: Treats seizures, panic disorder, and anxiety. This medicine is a benzodiazepine.

L-2-hydroxyglutarate dehydrogenase
type: Class
subclass of: Gene

leucine-rich, glioma inactivated 1
type: Class
subclass of: Gene

lamin B2
type: Class
subclass of: Gene

lunapark, ER junction formation factor
type: Class
subclass of: Gene

uncharacterized LOC101927919
type: Class
subclass of: Gene

uncharacterized LOC102724058
type: Class
subclass of: Gene

Lacosamide
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Vimpat
synonym: RxCUI 623400
comment: Anti seizure medication
comment: Antiepileptic Drug
is defined by: Treats partial-onset seizures in certain patients with epilepsy. It is used in combination with other medicines.

Lambda Wave
type: Class
subclass of: Normal EEG Pattern
comment: Lambda waves refer to the sharp, transient waves with a duration of 160 to 250 milliseconds, occuring when an individual's eye is open, coming from occipital regions bilaterally when the individual's eyes are focused on an illuminated or patterned visual field.

Lamictal®
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 196502
comment: Treats certain types of seizures and mood disorders. Often used along with other medicines.

Lamotrigine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Lamictal®
comment: Anti seizure medication
comment: Antiepileptic Drug, Neuroleptic Drug
is defined by: Treats certain types of seizures and mood disorders. Often used along with other medicines.
see also: RxCUI 28439

Larval Zebrafish
type: Class
subclass of: Zebrafish

Laser Guided Interstitial Therapy
type: Class
subclass of: Epilepsy Surgery

Gastaut type
type: Class
subclass of: Single Focal Epilepsy
label: Late-onset Childhood Occipital Epilepsy

Lateral Frontal Epilepsy
type: Class
subclass of: Frontal Lobe Epilepsy
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: Class
    union of: Non-Specific Aura
    union of: Motor Seizure

Lateral Frontal
type: Class
subclass of: Frontal

Lateral Hypothalamic Region
type: Class
subclass of: Hypothalamus Zone
comment: The lateral hypothalamus or lateral hypothalamic area is a part of the hypothalamus. It is concerned with hunger. Damage to this area can cause reduced food intake. Stimulating the lateral hypothalamus causes a desire to eat, while stimulating the ventromedial hypothalamus causes a desire to stop eating.

Lateral Hypothalamus Zone
type: Class
subclass of: Hypothalamus Zone

Lateral Lemniscus Trigone
type: Class
subclass of: Metencephalon Zone

Lateral Occipital Epilepsy
type: Class
subclass of: Occipital Lobe Epilepsy

Lateral Parietal Epilepsy
type: Class
subclass of: Parietal Lobe Epilepsy

Lateral Parietal
type: Class
subclass of: ParietalLobeSegment

Lateral Temporal Epilepsy
type: Class
subclass of: Temporal Lobe Epilepsy
subclass of: Restriction
  on property: hasEtiology
  some values from: Class
    union of: DNET
    union of: Cortical Dysplasia
    union of: GG
subclass of: Restriction
  on property: hasIctalEpileptiformAbnormality
  some values from: EEG-SZ
subclass of: Restriction
  on property: hasInterIctalEpileptiformAbnormality
  some values from: Class
    union of: Sharp Wave
    union of: Spike
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: Class
    union of: Auditory Aura
    union of: Automotor Seizure
    union of: Clonic Seizure
    union of: Postictal Nose Wiping
    union of: Postictal Todd's Paralysis
    union of: ConvulsiveMotorSeizure
    union of: Versive Seizure

Lateral Temporal
type: Class
subclass of: TemporalLobeSegment

Lateralizing Sign
type: Class
subclass of: Seizure feature
subclass of: Restriction
  on property: isLocatedAt
  some values from: Human Body Part
comment: Lateralizing Sign refers to the sign that helps in lateralizing the epileptogenic zone.

Lateralizing Sign Version
type: Class
subclass of: Lateralizing Sign
subclass of: Restriction
  on property: isLocatedAt
  some values from: Class
    union of: Eye
    union of: Head

Latuda
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 1040032

Left Amygdala
type: Class
subclass of: Amygdalar

Left Arm
type: Class
subclass of: Arm

Left Basal Temporal
type: Class
subclass of: Basal Temporal

Left Big Toe
type: Class
subclass of: Big Toe

Left Brainstem Segment
type: Class
subclass of: Brainstem Segment

Left Cerebellum Hemisphere
type: Class
subclass of: Cerebellum Hemisphere

Left Cerebral Hemisphere
type: Class
subclass of: Cerebral Hemisphere
subclass of: Restriction
  on property: regional part of
  some values from: Telencephalon
comment: "Left cerebral hemisphere is one of two bilateral, largely symmetrical organ subdivisions within the telencephalon which contain the cerebral cortex and cerebral white matter." [FMA v3.1]

Left cingulate gyrus
type: Class
subclass of: Cingular

Left Dorsal Hypothalamic Area
type: Class
subclass of: Dorsal Hypothalamic Area

Left Eye
type: Class
subclass of: Eye

Left Foot
type: Class
subclass of: Foot

Left Forearm
type: Class
subclass of: Forearm

Left Fourth Toe
type: Class
subclass of: Fourth Toe

LeftFrontalLobe
type: Class
subclass of: FrontalLobe
comment: Left frontal lobe

Left Frontal Lobe Dorsolateral Zone
type: Class
subclass of: Frontal Lobe Dorsolateral Zone

Orbitobasal segment of left frontal lobe
type: Class
subclass of: Orbitobasal segment of frontal lobe

Left Basal Frontal
type: Class
subclass of: Basal Frontal
comment: Orbitofrontal segment of left frontal lobe

Left Frontal Pole
type: Class
subclass of: Frontal Pole
label: Left Fronto-Polar

Left Hand
type: Class
subclass of: Hand

Left Hippocampal Formation
type: Class
subclass of: Hippocampal Formation

Left hippocampus
type: Class
subclass of: Hippocampal

Left Index Finger
type: Class
subclass of: Index Finger

Left Insular
type: Class
subclass of: Insular
comment: Left insula

Anterior lobule of left insula
type: Class
subclass of: Anterior lobule of insula

Posterior lobule of left insula
type: Class
subclass of: Posterior lobule of insula

Left Lateral Frontal
type: Class
subclass of: Lateral Frontal

Left Lateral Parietal
type: Class
subclass of: Lateral Parietal

Left Lateral Temporal
type: Class
subclass of: Lateral Temporal

Left Leg
type: Class
subclass of: Leg

LeftLimbicLobe
type: Class
subclass of: LimbicLobe
comment: Left limbic lobe

Left Little Finger
type: Class
subclass of: Little Finger

Left Little Toe
type: Class
subclass of: Little Toe

Left Mesial Frontal
type: Class
subclass of: Mesial Frontal

Left Mesial Temporal
type: Class
subclass of: Mesial Temporal

Left Middle Finger
type: Class
subclass of: Middle Finger

Left Occipital
type: Class
subclass of: Occipital
comment: Left occipital lobe (FMA)

Left Occipital Pole
type: Class
subclass of: Occipital Pole

Left Occipital Pole Proper
type: Class
subclass of: Occipital Pole Proper

Left Parietal
type: Class
subclass of: Parietal
comment: Left parietal lobe

Left Ring Finger
type: Class
subclass of: Ring Finger

Left Second Toe
type: Class
subclass of: Second Toe

Left Shoulder
type: Class
subclass of: Shoulder

Left Sign of 4
type: Class
subclass of: Sign of 4
subclass of: Restriction
  on property: hasExtendedArm
  some values from: Left Arm

Left Sphenoidal
type: Class
subclass of: Sphenoidal

Right subiculum
type: Class
subclass of: Subiculum hippocampi

Left Temporal
type: Class
subclass of: Temporal
comment: Left temporal lobe

Left Temporal Pole
type: Class
subclass of: Temporal Pole
label: Left Temporal-Polar

Left Thigh
type: Class
subclass of: Thigh

Left Third Toe
type: Class
subclass of: Third Toe

Left Thumb
type: Class
subclass of: Thumb

Left & Right Sphenoidal
type: Class
subclass of: Sphenoidal

Leg
type: Class
subclass of: Middle Free Limb Segment
comment: The portion of the hindlimb that contains both the stylopod and zeugopod.

Lemniscal Trigone
type: Class
subclass of: Metencephalon Zone

Lennox-Gastaut Syndrome
type: Class
subclass of: Generalized Epilepsy
subclass of: Restriction
  on property: isTypeOfSyndrome
  some values from: Developmental Epileptic Encephalopathy

Lentiform nodular heterotopia
type: Class
subclass of: Nodular Heterotopias

EPT
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: VGKC Associated Protein
label: Epitempin-1
label: LGI Protein 1
label: Leucine Rich Glioma Inactivated Protein 1
label: UNQ775/PRO1569

LGI1AssociatedEncephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
subclass of: Restriction
  on property: hasAssociatedAntigen
  some values from: EPT
label: Leucine Rich Glioma Inactivated Protein 1 Associated Encephalitis

Immune cell
type: Class
subclass of: Nucleated Cell
subclass of: Restriction
  on property: isInfiltrating
  some values from: boolean
label: White blood cell

Leukoencephalopathy co-occurrent with bilateral anterior temporal lobe cysts (disorder)
type: Class
subclass of: Cerebral cyst (disorder)

Levetiracetam
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Keppra®
    union of: Keppra XR™
comment: Anti seizure medication
comment: Antiepileptic Drug
is defined by: Used to help control certain types of seizures caused by epilepsy. This medicine is an antiepileptic.
see also: RxCUI 114477

Levomepromazine Maleate
type: Class
subclass of: Precise Drug Ingredient
synonym: RxCUI 160372
comment: Levomepromazine in Germany and Methotrimeprazine in America is an aliphatic phenothiazine neuroleptic drug. It is a low-potency antipsychotic with strong analgesic and antiemetic properties.

Lexapro
type: Class
subclass of: Drug Brand Name
see also: RxCUI 352741

Limb Segment
type: Class
subclass of: Cardinal Body Part Subdivision
comment: A major subdivision of a mature or developing limb, including both skeletal elements (or the mesenchyme that gives rise to the skeletal elements) and associated tissues, such as muscle, connective tissue, integument. Examples: autopod region, zeugopod region, stylopod region, metapodial region, arm region. Excludes the limb girdles.

LimbicLobe
type: Class
subclass of: CerebralHemisphereLobe
comment: Limbic lobe (FMA)

Segment of gyrus of limbic lobe
type: Class
subclass of: BrainGyrusSegment

Limbitrol
type: Class
subclass of: Drug Brand Name
see also: RxCUI 28727

LiquADD
type: Class
subclass of: Drug Brand Name
see also: RxCUI 800481

Lisdexamfetamine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Lisdexamfetamine Dimesylate
subclass of: Restriction
  on property: hasTradename
  some values from: Vyvanse
comment: Neuroleptic Drug
see also: RxCUI 700810

Lisdexamfetamine Dimesylate
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 673579

Lithium
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Lithium Orotate
comment: Neuroleptic Drug
see also: RxCUI 6448

Lithium Orotate
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 28815

Little Finger
type: Class
subclass of: Finger

Little Toe
type: Class
subclass of: Toe

Lobar Epileptogenic Zone
type: Class
subclass of: Focal epileptogenic zone

Lofepramine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Lofepramine Hydrochloride
see also: Neuroleptic Drug
see also: RxCUI 6465

Lofepramine Hydrochloride
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 6294

Longitudinal
type: Class
subclass of: Anatomical Coordinate

Lorazepam
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Ativan
comment: Anti seizure medication
comment: Antiepileptic Drug
is defined by: Treats anxiety, anxiety with depression, and insomnia (trouble sleeping). This medicine is a benzodiazepine.
see also: RxCUI 6470

Lorcaserin
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Class
    intersection of: lorcaserin hydrochloride
    intersection of: lorcaserin hydrochloride anhydrous
    intersection of: lorcaserin hydrochloride hemihydrate
see also: RxCUI 1300701

lorcaserin hydrochloride
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 1300700

lorcaserin hydrochloride anhydrous
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 1808546

lorcaserin hydrochloride hemihydrate
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 1597623

Loss Of Consciousness (LOC) refers to complete unresponsiveness with postictal amnesia for the events that happened during the seizure.
type: Class
subclass of: Seizure consciousness state

Loss of myelination
type: Class
subclass of: White matter lesion

Low Glycemic Index Therapy
type: Class
subclass of: Metabolic Therapy

Low Grade Glioma
type: Class
subclass of: Glioma

Lubazodone
type: Class
subclass of: Drug Ingredient
comment: Neuroleptic Drug
version info: Discontinued after phase II clinical trials (Wikipedia)

Luminal
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 847470
comment: The short-term treatment of sleeplessness, the relief of anxiety, tension, and fear, and the treatment of certain types of seizures, especially in emergency situations.

Luminal
type: Class
subclass of: Anatomical Coordinate

Lurasidone
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Lurasidone Hydrochloride
subclass of: Restriction
  on property: hasTradename
  some values from: Latuda
comment: Antidepressant Drug
see also: RxCUI 1040028

Lurasidone Hydrochloride
type: Class
subclass of: Precise Drug Ingredient
synonym: RxCUI 1040027

Luvox
type: Class
subclass of: Drug Brand Name
see also: RxCUI 42687

B-cell lines
type: Class
subclass of: Cell Culture
label: LCL
label: Lymphoblastic Cell Line
label: b-lymphoblastoid lines

CD34
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: isUsedForMarkingCellularPattern
  some values from: Oncofetal antigen
label: Lymphocyte Antigen CD34
label: Myeloid 10

CD45
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: isUsedForMarkingCellularPattern
  some values from: Lymphocyte
label: Lymphocyte Antigen CD45

CD68
type: Class
subclass of: Biological Substance
label: Lymphocyte Antigen CD68

Lyrica
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 593441
comment: Treats nerve pain caused by diabetes or herpes zoster (shingles). Also treats partial onset seizures in adults and fibromyalgia (muscle pain and stiffness).

mitogen-activated protein kinase 8 interacting protein 2
type: Class
subclass of: Gene

membrane associated ring-CH-type finger 6
type: Class
subclass of: Gene

methyl-CpG binding protein 2
type: Class
subclass of: Gene

myocyte enhancer factor 2C
type: Class
subclass of: Gene

MIB1
type: Class
subclass of: Biological Substance
label: MIBE3 Ubiquitin Protein Ligase 1

microRNA 211
type: Class
subclass of: Gene

MN1 proto-oncogene, transcriptional regulator
type: Class
subclass of: Gene
label: meningioma (disrupted in balanced translocation) 1

methylthioribose-1-phosphate isomerase 1
type: Class
subclass of: Gene

mitochondrially encoded cytochrome c oxidase III
type: Class
subclass of: Gene

mitochondrially encoded tRNA phenylalanine
type: Class
subclass of: Gene

methenyltetrahydrofolate synthetase
type: Class
subclass of: Gene

myotubularin related protein 10
type: Class
subclass of: Gene

MYB proto-oncogene, transcription factor
type: Class
subclass of: Gene

MYB proto-oncogene like 1
type: Class
subclass of: Gene

Macroglial cell
type: Class
subclass of: Glial Cell
synonym: Macrogliocyte

Clasmatocyte
type: Class
subclass of: Immune cell
subclass of: Restriction
  on property: isMarkedBy
  some values from: CD68
label: histiocyte

Macropsia Status
type: Class
subclass of: Visual Illusion Status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Magnesium Valproate
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 134422

MRA
type: Class
subclass of: MR
label: magnetic resonance angiography

MR
type: Class
subclass of: Imaging Modality
label: MRI
label: Magnetic Resonance Imaging

MRS
type: Class
subclass of: Imaging Modality
label: Magnetic Resonance Spectroscopy

MEG
type: Class
subclass of: Electrophysiological Modality

Maprotiline
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Class
    intersection of: Maprotiline Hydrochloride
    intersection of: Maprotiline Mesylate
comment: Neuroleptic Drug
see also: RxCUI 6646

Maprotiline Hydrochloride
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 203126

Maprotiline Mesylate
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 236328

Marplan
type: Class
subclass of: Drug Brand Name
see also: RxCUI 152005

Material Anatomical Entity
type: Class
subclass of: Human Body Part
comment: Physical anatomical entity which has mass. Examples: hemoglobin molecule, mitochondrion, hepatocyte, erythrocyte, heart, head, blood, urine. (source: FMA)

mature B lymphocyte
type: Class
subclass of: B Cell
label: mature B-cell
label: mature B-lymphocyte

Activated microglia
type: Class
subclass of: Hortega cell
label: Mature Microglial Cell
label: Mature microglia
label: Reactive microglia

Measurement Method
type: Class
subclass of: Independent Continuant

Measurement Unit
type: Class
subclass of: Independent Continuant
comment: Similar to concept of measurement unit label defined in the Information Artifact Ontology.

MedialFrontalGyrus
type: Class
subclass of: Gyrus of frontal lobe
see also: Medial frontal gyrus

Medial Hypothalamus Zone
type: Class
subclass of: Hypothalamus Zone

Medial Parietal
type: Class
subclass of: MesialParietalLobeSegment

Median
type: Class
subclass of: Anatomical Coordinate

Medulla Oblongata
type: Class
subclass of: Neuraxis Zone

Medulla Oblongata Neural Tissue
type: Class
subclass of: Brain Neural Tissue Segment
subclass of: Restriction
  on property: regional part of
  some values from: Brain Neural Tissue
comment: Fmaid 268484

Medulla Pyramid
type: Class
subclass of: Medulla Oblongata

Mellaril
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 152018

Mellaril-S
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 218304

Memory T Cell
type: Class
subclass of: T Cell

Meningeal cyst (disorder)
type: Class
subclass of: Central Nervous System Cyst

Mental Retardation
type: Class
subclass of: General Learning Disability

Mesial Frontal Epilepsy
type: Class
subclass of: Frontal Lobe Epilepsy
subclass of: Restriction
  on property: hasEtiology
  some values from: Bifocal Encephalomalacia
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: Class
    union of: Bilateral Asymmetric Tonic Seizure
    union of: Hypermotor Seizure

Mesial Frontal
type: Class
subclass of: Frontal

Mesial Occipital Epilepsy
type: Class
subclass of: Occipital Lobe Epilepsy

Mesial Parietal Epilepsy
type: Class
subclass of: Parietal Lobe Epilepsy

Mesial Temporal
type: Class
subclass of: TemporalLobeSegment

Hippocampal Sclerosis
type: Class
subclass of: Sclerosis
label: Mesial Temporal Sclerosis

Mesoridazine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Serentil
comment: Antidepressant Drug
comment: Treats schizophrenia.
see also: RxCUI 6779

Metabolic Cause
type: Class
subclass of: Aetiology

Metabolic Therapy
type: Class
subclass of: Therapy
label: Metabolic Treatment

GRM1
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: Neurotransmitter receptor
label: GRM1-ALPHA
label: GRM1A
label: MGLUR1-ALPHA
label: MGLUR1A
label: Metabotropic Glutamate Receptor 1
label: SPINOCEREBELLAR ATAXIA 44
label: SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 13
label: mGluR1

Metabotropic Glutamate Receptor 1 Associated Encephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
subclass of: Restriction
  on property: hasAssociatedAntigen
  some values from: GRM1
label: mGluR1AssociatedEncephalitis

Metadate
type: Class
subclass of: Drug Brand Name
see also: RxCUI 594111

Metamorphopsia Status
type: Class
subclass of: Visual Illusion Status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Metastatic Tumor
type: Class
subclass of: Brain Tumor

Metencephalon
type: Class
subclass of: Brain Neural Tissue Segment
subclass of: Restriction
  on property: regional part of
  some values from: Brain Neural Tissue
comment: Fmaid 268531

Segment of Metencephalon Segment
type: Class
subclass of: Cell Part Cluster of Neuraxis
comment: A regional part of brain that is part of a metencephalon

Metencephalon Zone
type: Class
subclass of: Neuraxis Zone

Methotrimeprazine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Levomepromazine Maleate
comment: Neuroleptic Drug
see also: RxCUI 6852

GO:0071557
type: Class
subclass of: Biological Substance
label: H3K27
label: Methylation of Histone H3 on Lysine 27

Methylin
type: Class
subclass of: Drug Brand Name
see also: RxCUI 261572

Methylphenidate
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Methylphenidate Hydrochloride
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Concerta
    union of: Daytrana
    union of: Metadate
    union of: Methylin
    union of: Quillivant
    union of: Ritalin
comment: Neuroleptic Drug
see also: RxCUI 6901

Methylphenidate Hydrochloride
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 203188

Mianserin
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Mianserin Hydrochloride
see also: Neuroleptic Drug
see also: RxCUI 6929

Mianserin Hydrochloride
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 203127

Hortega cell
type: Class
subclass of: Glial Cell
subclass of: Restriction
  on property: isMarkedBy
  some values from: CD68
label: Microglia
label: Microglial Cell
label: brain macrophage
label: microgliocyte

Micropsia Status
type: Class
subclass of: Visual Illusion Status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

MAP1.2
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: Neural Development
label: MAP1.X
label: MAP1B
label: MAP1x
label: MAP5
label: Microtubule Associated Protein 1B

MAP2
type: Class
subclass of: Biological Substance
label: Microtubule Associated Protein 2

Midazolam
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Class
    intersection of: midazolam hydrochloride
    intersection of: MidazolamMaleate
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Nayzilam
    union of: Seizalam
see also: RxCUI 6960

midazolam hydrochloride
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 203128

MidazolamMaleate
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 142441

Mesencephalon
type: Class
subclass of: Cardinal Brain Segment

Midbrain Neural Tissue
type: Class
subclass of: Brain Neural Tissue Segment
see also: Fmaid 268529

Middle
type: Class
subclass of: Anatomical Coordinate

Anatomical midline point of skull
type: Class
subclass of: Anatomical Point of Skull
label: Median anatomical point of skull
label: Middle Anatomical Point of Skull

Middle Cranial Fossa
type: Class
subclass of: Cranial Fossa

Middle Finger
type: Class
subclass of: Finger

Middle Free Limb Segment
type: Class
subclass of: Cardinal Free Limb Segment

MiddleFrontalGyrus
type: Class
subclass of: Gyrus of frontal lobe
see also: Middle frontal gyrus

Intermediate temporal gyrus
type: Class
subclass of: TemporalLobeGyrus
label: Middle temporal gyrus

Midline Theta Rhythm
type: Class
subclass of: Rhythmic Benign Variant
comment: Midline theta rhythm occurs as a focal rhythm over the midline region and usually is most prominant in the central vertex (Cz) lead.

Mild Malformation of Cortical Development
type: Class
subclass of: White matter lesion
label: mMCD

Mild Malformation of Cortical Development With Oligodendroglial Hyperplasiaand Epilepsy
type: Class
subclass of: White matter lesion
comment: clusters of olig2 positive oligodendroglial cells

Milnacipran
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Milnacipran Hydrochloride
subclass of: Restriction
  on property: hasTradename
  some values from: Savella
comment: Neuroleptic Drug
see also: RxCUI 588250

Milnacipran Hydrochloride
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 30003

Mirtazapine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Remeron
comment: Neuroleptic Drug
see also: RxCUI 15996

Missense
type: Class
subclass of: "Molecular consequence represents effects on protein products from the alterations in the coding nucleotide sequence. " (https://www.ncbi.nlm.nih.gov/variation/docs/glossary/)
label: Missense Variant
label: missense_variant

MELAS
type: Class
subclass of: Genetic Mutation
label: Mitochondrial Encephalomyopathy Lactic Acidosis Stroke like Episodes

Mixed Astrocytic Oligodendroglial
type: Class
subclass of: Diffuse Glioma

Moclobemide
type: Class
subclass of: Drug Ingredient
comment: Neuroleptic Drug
see also: RxCUI 30121

Model System
type: Class
subclass of: Independent Continuant
label: Organism name

Model System Anxiety Scale
type: Class
subclass of: Model System Physiology Measurement Method

Model System Autism Scale
type: Class
subclass of: Model System Physiology Measurement Method

Model System Depression Scale
type: Class
subclass of: Model System Physiology Measurement Method

Model System Physiology Measurement Method
type: Class
subclass of: Measurement Method

Moderate Astrogliosis
type: Class
subclass of: Astrogliosis
subclass of: Restriction
  on property: hasValue
  qualified cardinality: 0
  on data range: integer

GFAP
type: Class
subclass of: Neuronal Loss
subclass of: Restriction
  on property: hasValue
  qualified cardinality: 1
  on data range: integer
label: Moderate Neuronal Loss

Modified Atkins Diet
type: Class
subclass of: Metabolic Therapy

Modifier Gene
type: Class
subclass of: Gene Attribute

"Molecular consequence represents effects on protein products from the alterations in the coding nucleotide sequence. " (https://www.ncbi.nlm.nih.gov/variation/docs/glossary/)
type: Class
subclass of: Genomic Variation
label: Molecular Consequence

MolecularImaging
type: Class
subclass of: NuclearMedicineImaging
see also: Molecular Imaging

Mononuclear Cell
type: Class
subclass of: Immune cell
label: mononuclear leukocyte
label: peripheral blood mononuclear cell

Monthly Seizure
type: Class
subclass of: Seizure Frequency Category
comment: LA32856-9 (LOINC Code)
comment: Monthly but not weekly (i.e., 1-3 per month)

Abnormal tissue appearance
type: Class
subclass of: Morphologic alteration
label: Morphologically Abnormal Structure

Morphologic alteration
type: Class
subclass of: Material Anatomical Entity
label: Morphologically Altered Body Structure

Motor Bereitschaftspotential
type: Class
subclass of: Scalp Recorded ERP Extracted Pattern

Motor Episode
type: Class
subclass of: Non-Epileptic Seizure

Motor Seizure
type: Class
subclass of: Epileptic Seizure
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Generalized Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Motor seizures are seizures in which the main manifestation is motor symptomatology.
comment: Unknown Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Motor Status
type: Class
subclass of: SE

Mice
type: Class
subclass of: Rodent
comment: Class names are singular (plural terms added as synonyms).

Mouth
type: Class
subclass of: Subdivision of Face
comment: The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes teeth, gums, lips, tongue and parts of the palate

Mu Rhythm
type: Class
subclass of: Normal EEG Pattern
comment: Mu rhythm refers to central rhythm of alpha activity frequency (usually 8 to 10 hz) in which the individual waves have an arch like shape.

Multi Focal Epilepsy
type: Class
subclass of: Focal Epilepsy

Multi Focal Epileptogenic Zone
type: Class
subclass of: Focal epileptogenic zone
label: Multiregional
label: Multiregional Epileptogenic Zone

Multi Lobar Epileptic Zone
type: Class
subclass of: Focal epileptogenic zone

Multicystic encephalomalacia (disorder)
type: Class
subclass of: Cerebral cyst (disorder)

Multinodular and vacuolating neuronal tumor
type: Class
subclass of: Brain Neuronal Tumor
subclass of: Restriction
  on property: WHO grading
  some values from: WHO grade I

Multiple Seizure
type: Class
subclass of: Seizure Frequency Category
subclass of: Restriction
  on property: hasValue
  some values from: Datatype
    on datatype: integer
    with restrictions:
      min inclusive: 2
comment: LA32853-6 (LOINC Code)
comment: Multiple per day (i.e., 4 days per week with >= 2 seizures)

MBP
type: Class
subclass of: Biological Substance
label: MBP3 Protein
label: Myelin Basic Protein

MOG
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: Adhesion Molecule
label: Myelin Oligodendrocyte Glycoprotein
label: Narcolepsy 7 (1 family)

MOGAssociatedEncephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
subclass of: Restriction
  on property: hasAssociatedAntigen
  some values from: MOG
label: Myelin Oligodendrocyte Glycoprotein Associated Encephalitis

Myelinating Schwann Cell
type: Class
subclass of: Schwann cell
label: Neurilemmal cell
label: Peripheral neuroglial cell

myeloid leukocyte
type: Class
subclass of: Immune cell

Myoclonic Episode
type: Class
subclass of: Simple Motor Episode

ConvulsiveMotorSeizure
type: Class
subclass of: Simple Motor Seizure
comment: Generalized Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Myoclonic seizures consists of muscle contractions of brief duration (less than 200 ms).
comment: Unknown Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
label: Myoclonic Seizure

Myoclonic Status
type: Class
subclass of: SimpleMotorStatus
comment: Myoclonic Status (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

MuscleCell
type: Class
subclass of: Somatic Cell

Mysoline®
type: Class
subclass of: Drug Brand Name
comment: Treats seizure disorders. Belongs to a class of drugs called anticonvulsants.
see also: RxCUI 203011

Myxoid Glioneuronal Tumor
type: Class
subclass of: Brain Glial Neuronal Tumor
subclass of: Restriction
  on property: hasAssociatedMutationIn
  some values from: Platelet-derived Growth Factor Receptor

Myxopapillary Ependymoma
type: Class
subclass of: Ependymal Tumor
subclass of: Restriction
  on property: WHO grading
  some values from: WHO grade I

N-Methyl-D-Aspartate Receptor 1
type: Class
subclass of: Ionotropic Glutamate Receptor
subclass of: Restriction
  on property: hasFunction
  some values from: Neurotransmitter receptor
label: NDMA Receptor1
label: NDMAR1

N-Methyl-D-Aspartate Receptor 1 Associated Encephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
label: NDMAR1Encephalitis

N-Methyl D Aspartate
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: Protein
label: NMDA

nucleus accumbens associated 1
type: Class
subclass of: Gene

neurobeachin
type: Class
subclass of: Gene

NHL repeat containing E3 ubiquitin protein ligase 1
type: Class
subclass of: Gene

nidogen 1
type: Class
subclass of: Gene

natriuretic peptide receptor 2
type: Class
subclass of: Gene

NPR2 like, GATOR1 complex subunit
type: Class
subclass of: Gene

NPR3 like, GATOR1 complex subunit
type: Class
subclass of: Gene

nuclear receptor subfamily 4 group A member 2
type: Class
subclass of: Gene

NUS1 dehydrodolichyl diphosphate synthase subunit
type: Class
subclass of: Gene

N_Type Voltage-gated calcium channel
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: Ion Channel

Nasion
type: Class
subclass of: Anatomical midline point of skull
comment: "The craniometric point at the bridge of the nose where the frontal and nasal bones of the skull meet." (Foundational Model of Anatomy)

Natural Killer Cell
type: Class
subclass of: T Cell

Navane
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 227449

Nayzilam
type: Class
subclass of: Drug Brand Name
see also: RxCUI 2173495

Neck
type: Class
subclass of: Subdivision of Body Proper
comment: Subdivision of body proper, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the cervical vertebral coumn, it is partially surrounded by skin of neck. Examples: There is only one neck. (source: FMA)

Nefazodone
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Nefazodone Hydrochloride
subclass of: Restriction
  on property: hasTradename
  some values from: Serzone
comment: Neuroleptic Drug
see also: RxCUI 31565

Nefazodone Hydrochloride
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 236082

Negative Magnetic Resonance Imaging Finding
type: Class
subclass of: Radiological Examination Finding

Negative Myclonic Status
type: Class
subclass of: Special Status
label: Non-convulsive status epilepticus (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Negative Myoclonic Episode
type: Class
subclass of: Special Episode

Negative Myoclonic Seizure
type: Class
subclass of: Special Seizure
comment: Negative myoclonic seizures are short (30 to 40 ms) episodes of muscle atonia resulting in negative motor phenomena

Neonatal Seizures
type: Class
subclass of: Undetermined Epilepsy

Neonate
type: Class
subclass of: Human
subclass of: Restriction
  on property: hasRecordedAge
  max qualified cardinality: 1
  on class: Month
comment: newborn infant

Metastasis
type: Class
subclass of: Structural Cause

NG2 Glia
type: Class
subclass of: Macroglial cell
label: Nerve/glial antigen 2

Nervous System Measurement Modality
type: Class
subclass of: Independent Continuant
label: http://radlex.org/RID/RID10311

Neural Cell
type: Class
subclass of: Somatic Cell

Neural Development
type: Class
subclass of: Protein Function
comment: "Neural Development involves proliferation, differentiation, and/or maturation of neural cells." (National Cancel Institute Thesaurus)

Neural Precusor Cell
type: Class
subclass of: Neural Cell
label: Neural Stem Cell

Cell Part Cluster of Neuraxis
type: Class
subclass of: Cell Part Cluster
comment: A multi cell component structure that is part of a central nervous system

Ganglion of Neuraxis
type: Class
subclass of: Internal Gray Matter Component

Gray Matter of Neuraxis
type: Class
subclass of: Cell Part Cluster of Neuraxis
comment: Cell part cluster consisting predominantly of somas of neurons in the brain and the spinal cord. (source: FMA)

Neuraxis Segment
type: Class
subclass of: Organ Segment
comment: Organ segment of neuraxis with one or more fixed fiat boundaries. Examples: brain, brainstem, spinal cord. (FMA v3.1)

Neuraxis Zone
type: Class
subclass of: Cell Part Cluster of Neuraxis
comment: Anatomical cluster which has as direct parts cell parts from two or more cells.

Neuro Modulator
type: Class
subclass of: Independent Continuant

Neuro Transmitter
type: Class
subclass of: Biological Substance

NF-M20 PhosphorylationIndependent
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: isUsedForMarkingCellularPattern
  some values from: Dysmorphic Neurons
label: NF-SMI32 Unphosphorelated
label: Neurofilament Heavy Unphosphorelated
label: SMI311

Neuroglial cyst (disorder)
type: Class
subclass of: Central Nervous System Cyst

Neurological Exam Finding
type: Class
subclass of: Clinical Finding

Neuronal Loss
type: Class
subclass of: Measurement Unit
subclass of: Restriction
  on property: makesUseOf
  some values from: NeuN
comment: Tested using NeuN immunoreactivity

NeuN
type: Class
subclass of: Biological Substance
label: Neuronal Nuclei

Neurontin®
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 196498
comment: Treats certain types of seizures, called partial seizures, in people who have epilepsy. Also treats Restless Legs Syndrome (RLS) and pain caused by shingles (postherpetic neuralgia).

Neuropathic Atrophy
type: Class
subclass of: Atrophy (morphologic abnormality)

Neuropsychiatric Problem
type: Class
subclass of: Disorder
label: Neuropsychiatric abnormalities

Neurostimulation Therapy
type: Class
subclass of: Therapy

Neurotransmitter receptor
type: Class
subclass of: Protein Function

Neurotransmitter synthesis
type: Class
subclass of: Protein Function

Neurotrophic atrophy (morphologic abnormality)
type: Class
subclass of: Atrophy (morphologic abnormality)

Night Terror
type: Class
subclass of: Sleep disorder

No neuronal loss
type: Class
subclass of: Neuronal Loss
subclass of: Restriction
  on property: hasValue
  qualified cardinality: 0
  on data range: integer

Nodular Heterotopias
type: Class
subclass of: Heterotopia

Non-physical anatomical entity
type: Class
subclass of: Anatomical entity

No Clinical Signs
type: Class
subclass of: Epileptic Seizure
label: Non-Convulsive Seizure
label: Obtundation status
label: SubClinicalSeizure

NonDiffuse Glioma
type: Class
subclass of: Brain Glial Tumor

Non-Epileptic Seizure
type: Class
subclass of: Paroxysmal Event
comment: Episode Semiology #OPIC#
comment: Non-epileptic seizures mimic an epileptic seizure but do not involve abnormal, rhythmic discharges of cortical neurons.

Non Human Primate
type: Class
subclass of: Model System
label: Non-Human Primate
label: Non-humanPrimate

Non-Myelinating Schwann Cell
type: Class
subclass of: Schwann cell

Non-Nucleated Cell
type: Class
subclass of: Haematopoietic Cell

Non Somatotopic
type: Class
subclass of: Somatotopic Arrangement
comment: Non-somatotopic Semiological Distribution refers to the distribution in which there is no maintenance of spatial organization within the central nervous system. [Wikipedia]

Non-24-Hour-Sleep-Wake-Syndrome
type: Class
subclass of: Sleep disorder
label: Non-Twenty-Four Hour Sleep Wake Syndrome

Nonsense
type: Class
subclass of: "Molecular consequence represents effects on protein products from the alterations in the coding nucleotide sequence. " (https://www.ncbi.nlm.nih.gov/variation/docs/glossary/)
label: Nonsense Variant
label: stop_gained

Norepinephrine bitartrate
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: Neuro Transmitter

Normal Developmental Status
type: Class
subclass of: Developmental Status

Normal EEG Pattern
type: Class
subclass of: EEG Pattern
label: Normal Electroencephalogram Pattern

Normal Neurological Exam Finding
type: Class
subclass of: Neurological Exam Finding
comment: Normal

Norpramin
type: Class
subclass of: Drug Brand Name
see also: RxCUI 203771

Nortriptyline
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Nortriptyline Hydrochloride
subclass of: Restriction
  on property: hasTradename
  some values from: Pamelor
comment: Neuroleptic Drug
see also: RxCUI 7531

Nortriptyline Hydrochloride
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 203130

Not Classified SUDEP
type: Class
subclass of: SUDEP
label: Not Classified Sudden Unexpected Death in Epilepsy

NSF
type: Class
subclass of: Model System Anxiety Scale
label: Novelty-suppressed feeding

Noxene
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 541408

NuclearMedicineImaging
type: Class
subclass of: Imaging Modality
see also: Nuclear Medicine Imaging

Nucleated Cell
type: Class
subclass of: Haematopoietic Cell

OTU deubiquitinase 6B
type: Class
subclass of: Gene

OTU deubiquitinase 7A
type: Class
subclass of: Gene

OB
type: Class
subclass of: Model System Autism Scale
label: Object burying

Obsessive compulsive disorder
type: Class
subclass of: Neuropsychiatric Problem

Obstructive Sleep Apnea
type: Class
subclass of: Apnea

Occipital 10-10 System
type: Class
subclass of: 10-10 System

Occipital Intermittent Rhythmic Delta Activity
type: Class
subclass of: Slow Activity
subclass of: Restriction
  on property: isLocatedAt
  some values from: Occipital

Occipital
type: Class
subclass of: CerebralHemisphereLobe
comment: Occipital lobe is the one of five lobes of the cerebral hemisphere which occupies the posterior-most portion of the hemisphere. Anteriorly, it shares an arbitrary border with the parietal lobe and temporal lobe. Medially, it is bounded by the longitudinal cerebral fissure. (FMA)

Occipital Lobe Epilepsy
type: Class
subclass of: Single Focal Epilepsy
subclass of: Restriction
  on property: hasEtiology
  some values from: Class
    union of: Encephalitis
    union of: Glioma
    union of: Traumatic Brain Injury
subclass of: Restriction
  on property: hasIctalEpileptiformAbnormality
  some values from: EEG-SZ
subclass of: Restriction
  on property: hasInterIctalEpileptiformAbnormality
  some values from: Class
    union of: Sharp Wave
    union of: Spike
subclass of: Restriction
  on property: hasSeizureOnsetZone
  some values from: OccipitalLobeSegment
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: Visual Hallucination

Occipital Pole
type: Class
subclass of: Telencephalon Zone

Occipital Pole Epilepsy
type: Class
subclass of: Occipital Lobe Epilepsy

Occipital Pole Proper
type: Class
subclass of: Telencephalon Zone

Ohtahara Syndrome
type: Class
subclass of: Generalized Epilepsy
subclass of: Restriction
  on property: isTypeOfSyndrome
  some values from: Developmental Epileptic Encephalopathy

Olanzapine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Symbyax
    union of: Zyprexa
comment: Antidepressant Drug
see also: RxCUI 61381

Olfactory Aura
type: Class
subclass of: Non-Specific Aura
comment: Sensory (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: olfactory aura, uncinate epilepsy A sudden disagreeable sensation of smell, or odor, preceding or characterizing an epileptic attack

Olfactory Aura Status
type: Class
subclass of: Aura status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Olfactory Trigone
type: Class
subclass of: Telencephalon Zone

Oligodendrocyte
type: Class
subclass of: Macroglial cell
synonym: Oligodendrocytus
synonym: Oligodendroglia cell
synonym: Oligodendroglial cell

OLIG-2 Protein
type: Class
subclass of: Biological Substance
comment: "A basic helix-loop-helix transcription factor that is required for differentiation of OLIGODENDROCYTES and motor neurons in the spinal cord, and development of somatic motor neurons in the hindbrain." (MeSH definition)
label: OLIG2 Protein
label: Olig2
label: Oligodendrocyte Transcription Factor

Oligoastrocytoma
type: Class
subclass of: Oligodendroglial
subclass of: Restriction
  on property: WHO grading
  some values from: Class
    union of: WHO_II
    union of: WHO_III

Oncofetal antigen
type: Class
subclass of: Biological Substance

One Dimensional Cartesian Spatial Coordinate Datum
type: Class
subclass of: Cartesian Spatial Coordinate Datum

One Dimensional X Coordinate Datum
type: Class
subclass of: One Dimensional Cartesian Spatial Coordinate Datum

Onfi®
type: Class
subclass of: Drug Brand Name
comment: Used in combination with other medications to treat seizures caused by Lennox-Gastaut syndrome, a severe form of childhood epilepsy that also causes developmental and behavior problems.
see also: RxCUI 1191051

OFT
type: Class
subclass of: Model System Anxiety Scale
label: Open Field

Opipramol
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Opipramol Hydrochloride
comment: Neuroleptic Drug
see also: RxCUI 7674

Opipramol Hydrochloride
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 82062

ODD
type: Class
subclass of: Neuropsychiatric Problem
see also: Oppositional defiant disorder

Oppositional defiant disorder co-occurrent with chronic irritability-anger
type: Class
subclass of: ODD

Oppositional defiant disorder without chronic irritability-anger with limited prosocial emotions
type: Class
subclass of: Oppositional defiant disorder co-occurrent with chronic irritability-anger
label: http://purl.bioontology.org/ontology/SNOMEDCT/724736002

Oppositional defiant disorder co-occurrent with chronic irritability-anger with normal prosocial emotions
type: Class
subclass of: Oppositional defiant disorder co-occurrent with chronic irritability-anger

Oppositional defiant disorder without chronic irritability-anger
type: Class
subclass of: ODD

OppositionalDefiantDisorderWithoutChronicIrritabilityAngerWithLimitedProsocialEmotions
type: Class
subclass of: Oppositional defiant disorder without chronic irritability-anger
see also: Oppositional defiant disorder without chronic irritability-anger with limited prosocial emotions

Orap
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 152165

Orbital gyrus
type: Class
subclass of: Gyrus of frontal lobe

Orbital Operculum
type: Class
subclass of: Telencephalon Zone

Orbito Frontal Epilepsy
type: Class
subclass of: Frontal Lobe Epilepsy
subclass of: Restriction
  on property: hasEtiology
  some values from: Class
    union of: Brain Tumor
    union of: Traumatic Brain Injury
    union of: Vascular Malformation
subclass of: Restriction
  on property: hasIctalEpileptiformAbnormality
  some values from: EEG-SZ
subclass of: Restriction
  on property: hasInterIctalEpileptiformAbnormality
  some values from: Class
    union of: Sharp Wave
    union of: Spike
subclass of: Restriction
  on property: hasPreferredMedication
  some values from: Phenytoin
subclass of: Restriction
  on property: hasSeizureOnsetZone
  some values from: Basal Frontal
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: Class
    union of: Autonomic Seizure
    union of: Hypermotor Seizure
    union of: Olfactory Aura

Organ Component Region
type: Class
subclass of: Cardinal Organ Part
comment: Cardinal organ part which is a fiat subdivision of an organ component. Examples: cervical part of wall of esophagus, mucosa of body of stomach. (FMA v3.1)

Organ Region
type: Class
subclass of: Cardinal Organ Part
comment: Cardinal organ part which is a fiat subdivision of an organ. Examples: lingula of left lung, tail of pancreas, artery, trochanter, nodulus of semilunar valve, right side of heart, duodenum, fundus of stomach. (FMA v3.1)

Organ Segment
type: Class
subclass of: Organ Region
comment: Organ region with one or more fixed or anchored fiat boundaries. Examples: artery, trunk of nerve, cervical part of esophagus, pelvic part of vagina, horn of thyroid cartilage, anterior segment of eyeball[FMA]

Organism Genotype
type: Class
subclass of: Dependent Continuant

Organism Phenotype
type: Class
subclass of: Dependent Continuant

Organism Strain
type: Class
subclass of: Organism Genotype
comment: CURE CDE (WG #1: Core and Death-Related Information)

Organotypic slice
type: Class
subclass of: Model System

Other Astrocytic Tumor
type: Class
subclass of: NonDiffuse Glioma

Other Genetic Generalized Epilepsy
type: Class
subclass of: Generalized Epilepsy

Other Glioma
type: Class
subclass of: NonDiffuse Glioma

Other Multi Focal Epilepsy
type: Class
subclass of: Multi Focal Epilepsy

Other Symptomatic Generalized Epilepsies
type: Class
subclass of: Generalized Epilepsy

Other Undetermined Epilepsies
type: Class
subclass of: Undetermined Epilepsy

Oxcarbazepine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Oxtellar
    union of: Trileptal®
comment: Anti seizure medication
comment: Antiepileptic Drug
is defined by: Used alone or together with other medicines to treat seizures caused by epilepsy in adults and children 2 years of age and older.
see also: RxCUI 32624

Oxtellar
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 1365655

prolyl 4-hydroxylase, transmembrane
type: Class
subclass of: Gene

Platelet-derived Growth Factor Receptor
type: Class
subclass of: Gene

peroxisomal biogenesis factor 2
type: Class
subclass of: Gene

phospholipase C beta 1
type: Class
subclass of: Gene

pyridoxal phosphate binding protein
type: Class
subclass of: Gene

DNA polymerase gamma, catalytic subunit
type: Class
subclass of: Gene

RNA polymerase I and III subunit C
type: Class
subclass of: Gene

PR/SET domain 8
type: Class
subclass of: Gene

prickle planar cell polarity protein 1
type: Class
subclass of: Gene

prickle planar cell polarity protein 2
type: Class
subclass of: Gene

protein kinase C alpha
type: Class
subclass of: Gene

P_Q_Type Voltage Gated Calcium Channel
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: Ion Channel
label: VGCC Type P/Q

Plainful Seizure
type: Class
subclass of: Somatosensory Aura

Painful Seizure Status
type: Class
subclass of: Somatosensory Aura Status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Palinopsia Status
type: Class
subclass of: Visual Illusion Status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Paliperidone
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Invega
comment: Antidepressant Drug
see also: RxCUI 679314

Pamelor
type: Class
subclass of: Drug Brand Name
see also: RxCUI 7866

PA
type: Class
subclass of: Model System Anxiety Scale
label: Panic attacks

PGNT
type: Class
subclass of: Brain Glial Neuronal Tumor
subclass of: Restriction
  on property: hasAssociatedMutationIn
  some values from: protein kinase C alpha
label: Papillary Glioneuronal Tumor

End of seizure paradoxical clonus
type: Class
subclass of: Lateralizing Sign
comment: Paradoxical Clonus refers to movement of body part at seizure end ipsilateral to the side of EEG seizure onset.
label: Paradoxical Clonus

37 kDa neuronal protein
type: Class
subclass of: Biological Substance
label: 37-kDa Ma1
label: MA1
label: PNMA1
label: Paraneoplastic Antigen Ma1
label: neuron- and testis-specific protein 1

Ma1AssociatedEncephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
subclass of: Restriction
  on property: hasAssociatedAntigen
  some values from: 37 kDa neuronal protein
label: Paraneoplastic Antigen Ma1 Associated Encephalitis

40 kDa neuronal protein
type: Class
subclass of: Biological Substance
label: KIAA0883
label: MA2
label: PNMA2
label: Paraneoplastic antigen Ma2
label: onconeuronal antigen Ma2
label: paraneoplastic neuronal antigen MM2

Ma2AssociatedEncephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
subclass of: Restriction
  on property: hasAssociatedAntigen
  some values from: 40 kDa neuronal protein
label: Paraneoplastic Antigen Ma2 Associated Encephalitis

Parasitic Cysts
type: Class
subclass of: Infection

Paresthetic Seizure
type: Class
subclass of: Somatosensory Aura

Paresthetic Status
type: Class
subclass of: Somatosensory Aura Status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Parietal 10-10 System
type: Class
subclass of: 10-10 System

Parietal
type: Class
subclass of: CerebralHemisphereLobe
comment: Parietal lobe is the one of five lobes of the cerebral hemisphere which occupies the dorsal-posterior portion of the hemisphere. It is bounded by the central sulcus on its anterior border and and by the longitudinal cerebral fissure on its medial border. Posteriorly it shares an arbitrary border with the occipital lobe. (FMA)

Parietal Lobe Epilepsy
type: Class
subclass of: Single Focal Epilepsy
subclass of: Restriction
  on property: hasAgeOfOnset
  some values from: Age
subclass of: Restriction
  on property: hasEtiology
  some values from: Class
    union of: Brain Tumor
    union of: Traumatic Brain Injury
subclass of: Restriction
  on property: hasIctalEpileptiformAbnormality
  some values from: EEG-SZ
subclass of: Restriction
  on property: hasInterIctalEpileptiformAbnormality
  some values from: Class
    union of: Sharp Wave
    union of: Spike
subclass of: Restriction
  on property: hasSeizureOnsetZone
  some values from: ParietalLobeSegment
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: Class
    union of: Aphasic Seizure
    union of: Somatosensory Aura

Parietal N400
type: Class
subclass of: Scalp Recorded ERP Extracted Pattern

Parieto-Opercular
type: Class
subclass of: BrainGyrus

Parietal P3b
type: Class
subclass of: Scalp Recorded ERP Extracted Pattern

Parieto Occipital Epilepsy
type: Class
subclass of: BiLobar Epilepsy

Paroxetine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Brisdelle
    union of: Paxil
    union of: Pexeva
comment: Neuroleptic Drug
see also: RxCUI 32937

Paroxysmal Event
type: Class
subclass of: Physiological pathological process
subclass of: Restriction
  on property: hasDuration
  some values from: Temporal Entity
subclass of: Restriction
  on property: isLocatedAt
  some values from: Human Body Part
subclass of: Restriction
  on property: occursAt
  some values from: Death
comment: Events are short, sudden, frequent and stereotyped symptoms that can be observed in various clinical conditions including epilepsy. Paroxysmal event refers to the seizures that cannot be classified with sufficient certainity as epileptic or nonepileptic.
label: Seizure Semiology

Parvalbumin Expressing Interneuron
type: Class
subclass of: Interneuron
subclass of: Restriction
  on property: isMarkedBy
  some values from: Parvalbumin

Pathogenic Mutation
type: Class
subclass of: Gene Attribute

Patient Care Management
type: Class
subclass of: Dependent Continuant
comment: "Providing for the full range of personal health services for diagnosis, treatment, follow-up and rehabilitation of patients." (MeSH)

Pattern Light Stimulus
type: Class
subclass of: Light

Paxil
type: Class
subclass of: Drug Brand Name
see also: RxCUI 114228

Subdivision of Pectoral Girdle
type: Class
subclass of: Limb Segment
comment: An organism subdivision that includes the pectoral girdle skeleton. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc)

Pelopsia Status
type: Class
subclass of: Visual Illusion Status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Pentazine Codeine
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 688896

PentazineVC
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 631706

Peri Ictal
type: Class
subclass of: Electroencephalogram Finding

Periciazine
type: Class
subclass of: Drug Ingredient
comment: Antidepressant Drug
is defined by: Used to control symptoms of hostility, impulsiveness, and aggressiveness when used with other medications in adults and children over 5 years old.
see also: RxCUI 8766

Peri-Ictal Headache
type: Class
subclass of: Lateralizing Sign
subclass of: Restriction
  on property: occursAt
  some values from: Peri Ictal

Peri-Ictal Water Drinking
type: Class
subclass of: Lateralizing Sign

Perineural satellite cell
type: Class
subclass of: Glial Cell
label: Perineuronal satellite oligodendroglial cell
label: Satellite oligodendrocyte

Periodic Lateralized Epileptiform Discharge (PLED)
type: Class
subclass of: Inter Ictal Pattern
comment: Sharp waves that are focal or hemispheric in distribution and occur in a periodic or semi-periodic fashion. They are called bi-PLEDs when they occur in both hemispheres but do so asynchronously between the two hemispheres

Nocturnal Mycolonus
type: Class
subclass of: Sleep disorder
label: NocturnalMycolonus
label: PLMD
label: Periodic Limb Movement Disorder

Periodic Pattern
type: Class
subclass of: Special Pattern
comment: Periodic pattern (PP) refers to relative stereotypical waveforms which are frequently epileptiform and have a relatively periodic repetition rate.

Peripheral myelin
type: Class
subclass of: Myelin
label: http://purl.bioontology.org/ontology/SNOMEDCT/14436008

Periventricular Hypothalamus Zone
type: Class
subclass of: Hypothalamus Zone

Permapanel
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: FYCOMPA
see also: RxCUI 1356552

Permitil
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 219172

Perphenazine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Etrafon
    union of: Trilafon
comment: Antidepressant Drug
is defined by: Treats the symptoms of certain mental disorders. May also be used to treat nausea and vomiting in adult patients. Belongs to a class of drugs called phenothiazines.
see also: RxCUI 8076

Pertofrane
type: Class
subclass of: Drug Brand Name
see also: RxCUI 8078

Pexeva
type: Class
subclass of: Drug Brand Name
see also: RxCUI 541657

PhenTussAD
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 539987

PhenTussDM
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 540019

Phenadoz
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 541158

Phenergan
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 152218

Phenergan Codeine
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 93766

Phenobarbital
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Alkabel
    union of: Bellatal
    union of: D-Tal
    union of: Donnapine
    union of: Donnatal
    union of: Haponal
    union of: Hyosophen
    union of: Luminal
    union of: Quadrinal
    union of: Servira
comment: Anti seizure medication
comment: Antiepileptic Drug
is defined by: Used to treat or prevent seizures. It is also used short-term to treat insomnia, or as a sedative before surgery.
see also: RxCUI 8134

Phenytek®
type: Class
subclass of: Drug Brand Name
comment: Treats seizures. This medicine is an anticonvulsant.
see also: RxCUI 352891

Phenytoin
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Di-Phen
    union of: Dilantin®
    union of: Euthasol
    union of: Phenytek®
synonym: RxCUI 8183
comment: Anti seizure medication
comment: Antiepileptic Drug
is defined by: Treats seizures. This medicine is an anticonvulsant.

Oncogene protein P53
type: Class
subclass of: Biological Substance
label: TP53

pS6
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: isUsedForMarkingCellularPattern
  some values from: Class
    intersection of: Balloon Cell
    intersection of: Dysmorphic Neurons

Photoparoxysmal Response (PR)
type: Class
subclass of: Inter Ictal Pattern
comment: Photoparoxysmal response (PR) refers to posterior dominant or generalized epileptiform discharges elicited by photic stimulation.

Photosensitive Seizure
type: Class
subclass of: Stimulus Induced Seizure

Physiological Data
type: Class
subclass of: Dependent Continuant
comment: http://purl.bioontology.org/NEMO/ontology/NEMO.owl#NEMO_0000492

Physiological pathological process
type: Class
subclass of: Physiological process

Physiological process
type: Class
subclass of: Processual Entity

PA
type: Class
subclass of: Other Astrocytic Tumor
subclass of: Restriction
  on property: hasAssociatedMutationIn
  some values from: Class
    union of: B-Raf proto-oncogene
    union of: KIAA1549
subclass of: Restriction
  on property: WHO grading
  some values from: WHO grade I
label: Pilocytic Astrocytoma

Pilomotor Seizure
type: Class
subclass of: Autonomic Seizure

Pimozide
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Orap
comment: Antidepressant Drug
see also: RxCUI 8331

Cyst of pineal gland (disorder)
type: Class
subclass of: Cerebral cyst (disorder)

Pituitary cyst (disorder)
type: Class
subclass of: Cerebral cyst (disorder)

Plasma Cell
type: Class
subclass of: B Cell

Platelets Cell Line
type: Class
subclass of: Cell Culture
label: platelets

PXA
type: Class
subclass of: Other Astrocytic Tumor
subclass of: Restriction
  on property: WHO grading
  some values from: Class
    union of: WHO_II
    union of: WHO_III
label: Pleomorhic Xanthoastrocytoma

PolySpikes
type: Class
subclass of: InterictalDischarge
comment: Polyspikes (PSP) refer to a pattern consisting of groups of three or more spikes appearing one after another with a frequency of more than 10 Hz.

PLNTY
type: Class
subclass of: Oligodendroglial
subclass of: Restriction
  on property: hasAssociatedMutationIn
  some values from: Class
    union of: B-Raf proto-oncogene
    union of: Fibroblast Growth Factor Receptor
subclass of: Restriction
  on property: WHO grading
  some values from: WHO grade I
label: Polymorphous Low-grade Neuroepithelial Tumor of the Young

Polyopia Status
type: Class
subclass of: Visual Illusion Status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Pons Neural Tissue
type: Class
subclass of: Brain Neural Tissue Segment
subclass of: Restriction
  on property: regional part of
  some values from: Metencephalon
comment: Fmaid 268533

Pontine Tegmentum Postrema Area
type: Class
subclass of: Metencephalon Zone

Pontocerebellar Trigone
type: Class
subclass of: Metencephalon Zone

Porencephalic cyst (disorder)
type: Class
subclass of: Cerebral cyst (disorder)

Positive Magnetic Resonance Imaging Finding
type: Class
subclass of: Radiological Examination Finding
comment: Similar to SNOMED CT class positive genetic finding (http://purl.bioontology.org/ontology/SNOMEDCT/412731001)

PET
type: Class
subclass of: NuclearMedicineImaging
label: Positron Emission Tomography

Possible SUDEP
type: Class
subclass of: SUDEP
label: Possible Sudden Unexpected Death in Epilepsy

Post Ictal
type: Class
subclass of: Electroencephalogram Finding

Post Ictal Apnea
type: Class
subclass of: Induced apnea

Posterior Cingulate Epilepsy
type: Class
subclass of: Cingulate Epilepsy
subclass of: Restriction
  on property: hasIctalEpileptiformAbnormality
  some values from: EEG-SZ
subclass of: Restriction
  on property: hasIctalOnsetZone
  some values from: Temporal
subclass of: Restriction
  on property: hasInterIctalEpileptiformAbnormality
  some values from: Class
    union of: Sharp Wave
    union of: Spike
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: Class
    union of: Abdominal Aura
    union of: Automotor Seizure
    union of: Dialeptic Seizure
    union of: Psychic Aura
    union of: Simple Motor Seizure

Posterior Cranial Fossa
type: Class
subclass of: Cranial Fossa

Posterior Hypothalamic Zone
type: Class
subclass of: Hypothalamus Zone
subclass of: Restriction
  on property: receives input from
  some values from: Lateral Hypothalamic Region

Posterior Median Eminence
type: Class
subclass of: Diencephalon Zone

Posterior Slow Waves of Youth
type: Class
subclass of: Normal EEG Pattern
comment: Posterior slow waves of youth, also referred to as single delta frequency waves, referes to 2.5 to 4.5 Hz waves occuring in the posterior head regions of children and adolescents.

Posterior Temporal Epilepsy
type: Class
subclass of: Temporal Lobe Epilepsy

Posterior transverse temporal convolution of Heschl
type: Class
subclass of: TemporalLobeGyrus
label: Posterior transverse temporal gyrus

Posterotemporal N2c
type: Class
subclass of: Scalp Recorded ERP Extracted Pattern

Postictal Aphasia
type: Class
subclass of: Lateralizing Sign
subclass of: Restriction
  on property: occursAt
  some values from: Post Ictal
comment: Postictal aphasia is impairment of speech during or after episode of seizure.

Postictal Memory Dysfunction
type: Class
subclass of: Lateralizing Sign

Postictal Nose Wiping
type: Class
subclass of: Lateralizing Sign
subclass of: Restriction
  on property: makesUseOf
  some values from: Class
    union of: Left Hand
    union of: Right Hand

Postictal Todd's Paralysis
type: Class
subclass of: Lateralizing Sign
comment: Postictal todd's paralysis refers to the focal weakness occuring in a part of body after seizure.

Posture At Death
type: Class
subclass of: Clinical Finding

Potiga
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 1112994
comment: Used to treat partial-onset seizures in adults.

Pre Baseline
type: Class
subclass of: EEG event

Precentral convolution
type: Class
subclass of: Gyrus of frontal lobe
label: Precentral gyrus
label: Prerolandic gyrus

Precentral Operculum
type: Class
subclass of: Telencephalon Zone

Precise Drug Ingredient
type: Class
subclass of: ClinicalDrugComponent

Precocious Puberty
type: Class
subclass of: Endocrine Disorder

Prefrontal Epilepsy
type: Class
subclass of: Lateral Frontal Epilepsy
subclass of: Restriction
  on property: hasIctalEpileptiformAbnormality
  some values from: EEG-SZ
subclass of: Restriction
  on property: hasInterIctalEpileptiformAbnormality
  some values from: Class
    union of: Sharp Wave
    union of: Spike
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: Class
    union of: Automotor Seizure
    union of: Gelastic Seizure
    union of: Hypermotor Seizure

Pregabalin
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Lyrica
comment: Anti seizure medication
comment: Antiepileptic Drug
is defined by: Treats nerve pain caused by diabetes or herpes zoster (shingles). Also treats partial onset seizures in adults and fibromyalgia (muscle pain and stiffness).
see also: RxCUI 187832

Premature Mortality
type: Class
subclass of: Physiological process
subclass of: Restriction
  on property: hasPosture
  some values from: Posture At Death

Premotor Epilepsy
type: Class
subclass of: Lateral Frontal Epilepsy

Prenatal Birth Injury
type: Class
subclass of: Structural Cause

Preoptic Area
type: Class
subclass of: Hypothalamus Zone
subclass of: Restriction
  on property: regional part of
  some values from: AnteriorHypothalamicRegion
comment: Area of the forebrain anterior to the posterior tuberculum and the hypothalamus and ventral to the ventral thalamus[ZFA]

Primary Reading Epilepsy
type: Class
subclass of: Generalized Epilepsy
subclass of: Restriction
  on property: hasAssociatedMutationIn
  some values from: Class
    union of: calcium channel, voltage-dependent, beta 4 subunit
    union of: chloride channel, voltage-sensitive 2
    union of: EF-hand domain (C-terminal) containing 1
    union of: gamma-aminobutyric acid (GABA) A receptor, alpha 1
    union of: gamma-aminobutyric acid (GABA) A receptor, delta
subclass of: Restriction
  on property: hasEtiology
  some values from: Genetic Mutation
subclass of: Restriction
  on property: hasPreferredMedication
  some values from: Class
    union of: Lamotrigine
    union of: Levetiracetam
    union of: Topiramate
    union of: Valproate
    union of: Zonisamide
subclass of: Restriction
  on property: hasSemiologyFeature
  some values from: ConvulsiveMotorSeizure
subclass of: Restriction
  on property: hasAgeOfOnset
  min qualified cardinality: 8
  on class: Year
subclass of: Restriction
  on property: hasAgeOfOnset
  max qualified cardinality: 20
  on class: Year

Primazine
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 545267

Primidone
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Mysoline®
synonym: RxCUI 8691
comment: Anti seizure medication
comment: Antiepileptic Drug
is defined by: Treats seizure disorders. Belongs to a class of drugs called anticonvulsants.

Principal Neuron
type: Class
subclass of: Neuron

Pristiq
type: Class
subclass of: Drug Brand Name
see also: RxCUI 711372

ProCentra
type: Class
subclass of: Drug Brand Name
see also: RxCUI 847176

Probable SUDEP
type: Class
subclass of: SUDEP
label: Probable Sudden Unexpected Death in Epilepsy

Prochlorperazine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Compazine
    union of: Compro
comment: Antidepressant Drug
is defined by: Treats severe nausea and vomiting. Belongs to a class of drugs called phenothiazines.
see also: RxCUI 8704

PME
type: Class
subclass of: Generalized Epilepsy
label: Progressive Myoclonus Epilepsy

Prolixin
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 8741

Promacot
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 219440

Promazine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Primazine
comment: Antidepressant Drug
is defined by: Used for short-term management of moderate to severe agitation, agitation and restlessness in elderly people.
see also: RxCUI 8742

Promethazine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Promethegan
comment: Antidepressant Drug
is defined by: Prevents and controls motion sickness, nausea, vomiting, and dizziness. Also used to relieve or prevent allergic reactions, helps people go to sleep, and control their pain or anxiety before or after surgery or other procedures.
see also: RxCUI 8745

Promethegan
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 219442

Prostatic Sinus Space
type: Class
subclass of: Anatomical Space

Protein Function
type: Class
subclass of: Dependent Continuant
label: Protein metabolic function

Proximal Free Limb Segment
type: Class
subclass of: Cardinal Free Limb Segment

Prozac
type: Class
subclass of: Drug Brand Name
see also: RxCUI 58827

Prudoxin
type: Class
subclass of: Drug Brand Name
see also: RxCUI 261625

Psychic Aura
type: Class
subclass of: Non-Specific Aura
comment: Cognitive (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

PCA1AssociatedEncephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
subclass of: Restriction
  on property: hasAssociatedAntigen
  some values from: PCA1
label: Purkinje Cell Antibody 1 Associated Encephalitis

PCA1
type: Class
subclass of: Biological Substance
label: Purkinje Cell Antibody Type 1

Pyramidal Neuron
type: Class
subclass of: Neuron

Pyschic Aura Status
type: Class
subclass of: Aura status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Qsymia
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 1372703

Quadrinal
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 35177

Quetiapine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Seroquel
comment: Antidepressant Drug
see also: RxCUI 51272

Quillivant
type: Class
subclass of: Drug Brand Name
see also: RxCUI 1312584

RAB, member of RAS oncogene family like 2B
type: Class
subclass of: Gene

RNA binding fox-1 homolog 1
type: Class
subclass of: Gene

RNA binding fox-1 homolog 3
type: Class
subclass of: Gene

RELA proto-oncogene, NF-kB subunit
type: Class
subclass of: Gene

reelin
type: Class
subclass of: Gene

RAR related orphan receptor A
type: Class
subclass of: Gene

RAR related orphan receptor B
type: Class
subclass of: Gene

Radial glial fiber
type: Class
subclass of: Neural Precusor Cell
synonym: Radial glial cell

Radiological Examination Finding
type: Class
subclass of: Clinical Finding

RBD
type: Class
subclass of: Sleep disorder
label: Rapid Eye Movement Behavior Disorder

Rapiflux
type: Class
subclass of: Drug Brand Name
see also: RxCUI 352940

Rasmussen Encephalitis
type: Class
subclass of: Encephalitis

Rasmussen Syndrome
type: Class
subclass of: Multi Focal Epilepsy

Rats
type: Class
subclass of: Rodent
comment: Class names are singular (plural terms added as synonyms).

Reactivity Pattern
type: Class
subclass of: Activation Procedure
comment: Reactivity refers to the description/specification of reactions, or responses, of the various components of the EEG to certain ohysiological changes or provocations.

Reconcile
type: Class
subclass of: Drug Brand Name
see also: RxCUI 729704

Reflex Epilepsies
type: Class
subclass of: Generalized Epilepsy

Remeron
type: Class
subclass of: Drug Brand Name
see also: RxCUI 134774

Respiratory Rate
type: Class
subclass of: Physiological Data

RNS
type: Class
subclass of: Neurostimulation Therapy
label: Responsive Neuro Stimulation

RestingStateImaging
type: Class
subclass of: fMRI
comment: Resting State

Restless Leg Syndrome
type: Class
subclass of: Sleep disorder

Retro Olivary Area
type: Class
subclass of: Medulla Oblongata

Retrochiasmatic Area
type: Class
subclass of: Hypothalamus Zone
subclass of: Restriction
  on property: regional part of
  some values from: Intermediate Hypothalamic Region

Postictal Return to Baseline
type: Class
subclass of: EEG event

Reversal Learning in T-Maze
type: Class
subclass of: Model System Autism Scale

Rhythmic Benign Variant
type: Class
subclass of: Benign EEG Pattern
comment: Rhythmic benign variants consist of rhythmic activity that may be in the theta, alpha, or beta frequency ranges.

Rhytmic Temporal Theta Bursts of Drowsiness
type: Class
subclass of: Rhythmic Benign Variant
comment: Rhythmic temporal theta bursts of drowsiness (psychomotor variant) is characterized by bursts or serial trains of rhythmic theta waves ranging from 5 to 7 hz with a flat-topped, sharp-contoured, or notched appearance.

Right Amygdala
type: Class
subclass of: Amygdalar

Right Arm
type: Class
subclass of: Arm

Right Basal Temporal
type: Class
subclass of: Basal Temporal

Right Big Toe
type: Class
subclass of: Big Toe

Right Brainstem Segment
type: Class
subclass of: Brainstem Segment

Right Cerebellum Hemisphere
type: Class
subclass of: Cerebellum Hemisphere

Right Cerebral Hemisphere
type: Class
subclass of: Cerebral Hemisphere
subclass of: Restriction
  on property: regional part of
  some values from: Telencephalon
comment: "The right cerebral hemisphere is one of two bilateral, largely symmetrical organ subdivisions within the telencephalon which contain the cerebral cortex and cerebral white matter." [FMA v3.1]

Right cingulate gyrus
type: Class
subclass of: Cingular

Right Dorsal Hypothalamic Area
type: Class
subclass of: Dorsal Hypothalamic Area

Right Eye
type: Class
subclass of: Eye

Right Foot
type: Class
subclass of: Foot

Right Forearm
type: Class
subclass of: Forearm

Right Fourth Toe
type: Class
subclass of: Fourth Toe

RightFrontalLobe
type: Class
subclass of: FrontalLobe
comment: Right frontal lobe

Right Frontal Lobe Dorsolateral Zone
type: Class
subclass of: Frontal Lobe Dorsolateral Zone

Orbitobasal segment of right frontal lobe
type: Class
subclass of: Orbitobasal segment of frontal lobe

Right Basal Frontal
type: Class
subclass of: Basal Frontal
comment: Orbitofrontal segment of right frontal lobe

Right Frontal Pole
type: Class
subclass of: Frontal Pole
label: Right Fronto-Polar

Right Hand
type: Class
subclass of: Hand

Right Hippocampal Formation
type: Class
subclass of: Hippocampal Formation

Right hippocampus
type: Class
subclass of: Hippocampal

Right Index Finger
type: Class
subclass of: Index Finger

Right Insular
type: Class
subclass of: Insular
comment: Right insula

Anterior lobule of right insula
type: Class
subclass of: Anterior lobule of insula

Posterior lobule of right insula
type: Class
subclass of: Posterior lobule of insula

Right Lateral Frontal
type: Class
subclass of: Lateral Frontal

Right Lateral Parietal
type: Class
subclass of: Lateral Parietal

Right Lateral Temporal
type: Class
subclass of: Lateral Temporal

Right Leg
type: Class
subclass of: Leg

RightLimbicLobe
type: Class
subclass of: LimbicLobe
see also: Right limbic lobe

Right Little Finger
type: Class
subclass of: Little Finger

Right Little Toe
type: Class
subclass of: Little Toe

Right Mesial Frontal
type: Class
subclass of: Mesial Frontal

Right Mesial Temporal
type: Class
subclass of: Mesial Temporal

Right Middle Finger
type: Class
subclass of: Middle Finger

Right Occipital
type: Class
subclass of: Occipital
comment: Right occipital lobe (FMA)

Right Occipital Pole
type: Class
subclass of: Occipital Pole

Right Occipital Pole Proper
type: Class
subclass of: Occipital Pole Proper

Right Parietal
type: Class
subclass of: Parietal
see also: Right parietal lobe

Right Ring Finger
type: Class
subclass of: Ring Finger

RightSecondToe
type: Class
subclass of: Second Toe
see also: Right Second Toe

Right Shoulder
type: Class
subclass of: Shoulder

Right Sign of 4
type: Class
subclass of: Sign of 4
subclass of: Restriction
  on property: hasExtendedArm
  some values from: Right Arm

Right Sphenoidal
type: Class
subclass of: Sphenoidal

Left subiculum
type: Class
subclass of: Subiculum hippocampi

Right Temporal
type: Class
subclass of: Temporal
comment: Right temporal lobe

Right Temporal Pole
type: Class
subclass of: Temporal Pole
label: Right Temporal-Polar

RightThigh
type: Class
subclass of: Thigh
see also: Right Thigh

Right Third Toe
type: Class
subclass of: Third Toe

Right Thumb
type: Class
subclass of: Thumb

Ring Finger
type: Class
subclass of: Finger

Ripple
type: Class
subclass of: High Frequency Oscillation
comment: ripples (80–200 Hz), Brain (2007) 130 (9): 2354-2366. doi: 10.1093/brain/awm149

Risperdal
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 152318

Risperidone
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Risperdal
synonym: RxCUI 35636
comment: Antidepressant Drug

Ritalin
type: Class
subclass of: Drug Brand Name
see also: RxCUI 224917

Rodent
type: Class
subclass of: Model System
comment: CURE CDE (WG #1: Core and Death-Related Information)

Rosette-forming glioneuronal neoplasm (morphologic abnormality)
type: Class
subclass of: Brain Glial Neuronal Tumor
synonym: Rosette-forming glioneuronal neoplasm
label: Rosette-forming glioneuronal tumor

Rufinamide
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Banzel
    union of: Inovelon®
comment: Anti seizure medication
comment: Antiepileptic Drug
is defined by: Treats seizures in patients who have Lennox-Gastaut syndrome (LGS).
see also: RxCUI 69036

sterile alpha motif domain containing 12
type: Class
subclass of: Gene

scavenger receptor class B member 2
type: Class
subclass of: Gene

sodium channel, voltage-gated, type I, alpha subunit
type: Class
subclass of: Gene
subclass of: Restriction
  on property: hasGeneAttribute
  some values from: Pathogenic Mutation
subclass of: Restriction
  on property: hasSequenceVariant
  some values from: Class
    union of: Allele ID: 79392
    union of: Allele ID: 79394
    union of: Allele ID: 79396
    union of: Allele ID: 79397
    union of: Allele ID: 79398
    union of: Allele ID: 79404
    union of: Allele ID: 79412
    union of: Allele ID: 79415

sodium channel, voltage-gated, type I, beta subunit
type: Class
subclass of: Gene
subclass of: Restriction
  on property: hasSequenceVariant
  all values from: VariationID60767

SCN1B SequenceVariant
type: Class
subclass of: Genetic Variant
comment: Sequence variant of gene SCN1B

sodium channel, voltage-gated, type II, alpha subunit
type: Class
subclass of: Gene

sodium voltage-gated channel alpha subunit 3
type: Class
subclass of: Gene

sodium voltage-gated channel alpha subunit 8
type: Class
subclass of: Gene

sodium voltage-gated channel alpha subunit 9
type: Class
subclass of: Gene

SET domain containing 1A, histone lysine methyltransferase
type: Class
subclass of: Gene

SET domain containing 1B, histone lysine methyltransferase
type: Class
subclass of: Gene

SH3 and multiple ankyrin repeat domains 3
type: Class
subclass of: Gene

salt inducible kinase 1
type: Class
subclass of: Gene

solute carrier family 2 member 1
type: Class
subclass of: Gene

solute carrier family 35 member F1
type: Class
subclass of: Gene

solute carrier family 6 member 1
type: Class
subclass of: Gene

synaptosome associated protein 25
type: Class
subclass of: Gene

Smad nuclear interacting protein 1
type: Class
subclass of: Gene

sorting nexin 27
type: Class
subclass of: Gene

sperm associated antigen 1
type: Class
subclass of: Gene
subclass of: Restriction
  on property: hasSequenceVariant
  some values from: Class
    union of: Allele ID: 94262
    union of: Allele ID: 94263

spermatogenesis associated 5
type: Class
subclass of: Gene

spectrin alpha, non-erythrocytic 1
type: Class
subclass of: Gene

sushi repeat containing protein X-linked 2
type: Class
subclass of: Gene

StAR related lipid transfer domain containing 7
type: Class
subclass of: Gene

STE20 related adaptor alpha
type: Class
subclass of: Gene

syntaxin 1B
type: Class
subclass of: Gene

MUNC18-1
type: Class
subclass of: Gene
label: Syntaxin binding protein 1

synapsin I
type: Class
subclass of: Gene

SZT2 subunit of KICSTOR complex
type: Class
subclass of: Gene

Sabril
type: Class
subclass of: Drug Brand Name
comment: Treats seizures (epilepsy). This medicine is an anticonvulsant.
see also: RxCUI 152332

Saphris
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 859976

Sarafem
type: Class
subclass of: Drug Brand Name
see also: RxCUI 639464

Savella
type: Class
subclass of: Drug Brand Name
see also: RxCUI 833136

Scalp Electrode
type: Class
subclass of: Electrode

Scalp Recorded EEG Data
type: Class
subclass of: Scalp Recorded ERP Data

Scalp Recorded ERP Data
type: Class
subclass of: Averaged EEG Data

Scalp Recorded ERP Extracted Pattern
type: Class
subclass of: Averaged EEG Data

Schwann cell
type: Class
subclass of: Glial Cell
synonym: Neurilemmal cell
synonym: Peripheral glial cell
synonym: Peripheral neuroglial cell

Second Toe
type: Class
subclass of: Toe

Seizalam
type: Class
subclass of: Drug Brand Name
see also: RxCUI 2057960

Cluster of Seizure
type: Class
subclass of: Paroxysmal Event
subclass of: Restriction
  on property: hasPart
  some values from: Class
    union of: Bilateral Seizure
    union of: Epileptic Seizure
    union of: Focal Seizure
    union of: Generalized Seizure
label: ClusterOfSeizure

Seizure consciousness state
type: Class
subclass of: Seizure feature
comment: Alterations in consciousness state in epilepsy

Seizure feature
type: Class
subclass of: Physiological pathological process

Seizure Frequency Category
type: Class
subclass of: Measurement Unit

Seizure Onset Zone
type: Class
subclass of: EpilepsyZone
comment: Area of cortex from which the seizure originates according to electroencephalogram recordings.

EEG-SZ
type: Class
subclass of: Ictal Pattern
comment: EEG-SZ accompanies a clinical seizure.
comment: Seizure pattern (EEG SZ) refers to the EEG pattern seen during epileptic seizures. This may be focal(localized), hemispheric (lateralized) or generalized.
label: Seizure Pattern

SG
type: Class
subclass of: Model System Autism Scale
label: Self-grooming

Senior
type: Class
subclass of: Adult
subclass of: Restriction
  on property: hasRecordedAge
  min qualified cardinality: 65
  on class: Year
comment: elderly adult

Sensory Seizure
type: Class
subclass of: No Clinical Signs

Cyst of septum pellucidum (disorder)
type: Class
subclass of: Cerebral cyst (disorder)

Genetic Variant
type: Class
subclass of: Genomic Variation
comment: Gene sequence variant. Linked to the NCBI ClinVar data repository.
label: GeneticVariant
label: Sequence Variant

Serentil
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 9670

Seroquel
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 83553

Sertindole
type: Class
subclass of: Drug Ingredient
comment: Antidepressant Drug
see also: RxCUI 41996

Servira
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 753345

Serzone
type: Class
subclass of: Drug Brand Name
see also: RxCUI 151679

Sesquient
type: Class
subclass of: Drug Brand Name
comment: Antiepileptic drug
see also: RxCUI 2476636

Set of Immaterial Anatomical Entities
type: Class
subclass of: Immaterial Anatomical Entity
comment: "Immaterial anatomical entity, each instance of which has three spatial dimensions. Examples: body cavity, thoracic cavity, lesser sac, cavity of right atrium, lumen of aorta, mediastinal space, space of anterior compartment of forearm." (Foundational Model of Anatomy)

Severe Neuronal Loss
type: Class
subclass of: Neuronal Loss
subclass of: Restriction
  on property: hasValue
  qualified cardinality: 2
  on data range: integer

SEX
type: Class
subclass of: Model System Depression Scale
label: Sexual behavior (Males)

Sexual Peroneal Sendory Seizure
type: Class
subclass of: Somatosensory Aura

Sexual Peroneal Sensory Status
type: Class
subclass of: Somatosensory Aura Status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Sexual Seizure
type: Class
subclass of: Autonomic Seizure

Sharp transient
type: Class
subclass of: EEG Pattern

Sharp Wave
type: Class
subclass of: InterictalDischarge
comment: Sharp waves refer to the epileptiform discharges 80 to 200 ms in duration

Shoulder
type: Class
subclass of: Subdivision of Pectoral Girdle
comment: In human anatomy, the shoulder joint comprises the part of the body where the humerus attaches to the scapula. The shoulder refers to the group of structures in the region of the joint. It is made up of three bones: the clavicle (collarbone), the scapula (shoulder blade), and the humerus (upper arm bone) as well as associated muscles, ligaments and tendons. The articulations between the bones of the shoulder make up the shoulder joints. There are two kinds of cartilage in the joint. The first type is the white cartilage on the ends of the bones (called articular cartilage) which allows the bones to glide and move on each other. When this type of cartilage starts to wear out (a process called arthritis), the joint becomes painful and stiff. The labrum is a second kind of cartilage in the shoulder which is distinctly different from the articular cartilage. This cartilage is more fibrous or rigid than the cartilage on the ends of the ball and socket. Also, this cartilage is also found only around the socket where it is attached. The shoulder must be flexible for the wide range of motion required in the arms and hands and also strong enough to allow for actions such as lifting, pushing and pulling. The compromise between these two functions results in a large number of shoulder problems not faced by other joints such as the hip.

Sialorrheic Seizure
type: Class
subclass of: Autonomic Seizure

Sign of 4
type: Class
subclass of: Lateralizing Sign

Silenor
type: Class
subclass of: Drug Brand Name
see also: RxCUI 966788

Simple Motor Episode
type: Class
subclass of: Motor Episode

Simple Motor Seizure
type: Class
subclass of: Motor Seizure
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Motor (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Simple motor seizures consists of unnatural, relatively simple movements of the type that can be elicited by stimulation of Broadmann areas 4 and 6.

SimpleMotorStatus
type: Class
subclass of: Motor Status
comment: Simple Motor Status

Simple Visual Hallucination
type: Class
subclass of: Visual Hallucination

Simple Visual Hallucination Status
type: Class
subclass of: Visual Hallucination Status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Single Focal Epilepsy
type: Class
subclass of: Focal Epilepsy

SNV
type: Class
subclass of: Variation Type
label: Single Nucleotide Variant

Situational Circadian Rhythm Sleep Disorder
type: Class
subclass of: Sleep disorder

Phantom spike and wave
type: Class
subclass of: Epileptiform Benign Variant
comment: Six-hertz spike-and-wave bursts (phantom spike and wave) are brief bursts, lasting 1 to 2 seconds with a repitition rate of 6Hz with a range of 5-7 hz.
label: Six-Hertz Spike Wave Burst

Defect of skull ossification (disorder)
type: Class
subclass of: Congenital anomaly of skull (disorder)

Sleep disorder
type: Class
subclass of: Disorder

Sleep Onset Rapid Eye Movement
type: Class
subclass of: Special Pattern
comment: Sleep-onset rapid eye movement (SOR) refers to the occurence of REM sleep less than 15 minutes after falling sleep.

Sleep Paralysis
type: Class
subclass of: Sleep disorder

Sleep Related EEG Pattern
type: Class
subclass of: Normal EEG Pattern
label: Sleep Related Electroencephalogram Pattern
label: SleepRelatedEEGPattern

SLEEP
type: Class
subclass of: Model System Depression Scale
label: Sleep structure

Sleep Talking
type: Class
subclass of: Sleep disorder
label: Somniloquy

Sleep Walking
type: Class
subclass of: Sleep disorder
label: Somnambulism

Sleeping Sickness
type: Class
subclass of: Sleep disorder

Slow Activity
type: Class
subclass of: Inter Ictal Pattern
subclass of: Restriction
  on property: hasInterIctalEpileptiformAbnormality
  some values from: Class
    union of: PolySpikes
    union of: Spike
comment: Slow activity is a general term referring to EEG activities that are abnormally slow for the age of the patient and regional or lateralized activity that is slowet than on the homotopic contralateral side.

Slow Alpha Variant
type: Class
subclass of: Alpha Variant
comment: Occurs at a harmonic half that of the alpha range

Slow Spike and Wave Complex
type: Class
subclass of: Spike and Wave Complex
comment: Slow spike-and-wave complexes (SSWC) refer to bursts of spike-and-wave complexes with a regular repetition rate of less than 2.5 Hz, with at least one burst of these complexes with a duration of more than 3 seconds.
label: Slow Spike-and-Wave Complex

SlowTransient
type: Class
subclass of: EEG Pattern
see also: Slow transient

SSS
type: Class
subclass of: Epileptiform Benign Variant
comment: Small sharp spikes (SSS) consist of single monophasic or diphasic spikes with an abrupt ascending limb and a steep descending limb, are generally of low voltage and short duratiopn, usually less than 50 ms.
label: Small Sharp Spike

STFP
type: Class
subclass of: Model System Autism Scale
label: Social transmission of food preference

sodium valproate
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 9919

Somatic Cell
type: Class
subclass of: Cell

Somatosensory Aura
type: Class
subclass of: Non-Specific Aura
comment: Sensory (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Somatosensory auras consists of paraesthesias, which have a clearly defined dermatomal distribution.

Somatosensory Aura Status
type: Class
subclass of: Aura status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Somatostatin Expressing Interneuron
type: Class
subclass of: Interneuron
subclass of: Restriction
  on property: isMarkedBy
  some values from: Somatostatin

Somatotopic
type: Class
subclass of: Somatotopic Arrangement
comment: Non-somatotopic Semiological Distribution refers to the distribution in which there is no maintenance of spatial organization within the central nervous system.

Somatotopic Arrangement
type: Class
subclass of: Dependent Continuant
comment: Somatotopy refers to the correspondence between the position of a receptor in part of the body and the corresponding area of the cerebral cortex that is activated by it. [Wikipedia]

Space of Compartment of Head
type: Class
subclass of: Anatomical Compartment Space

Special Episode
type: Class
subclass of: Non-Epileptic Seizure

Special Pattern
type: Class
subclass of: Abnormal EEG Pattern

Special Seizure
type: Class
subclass of: Epileptic Seizure
disjoint with: Class
  union of: Non-Specific Aura
  union of: Autonomic Seizure
  union of: Dialeptic Seizure
  union of: Motor Seizure
comment: Special seizures include all seizures that cannot be classified as auras, autonomic, dialeptic or motor seizures.

Special Status
type: Class
subclass of: SE

Spike
type: Class
subclass of: InterictalDischarge
comment: Spikes refer to epileptiform discharges with a duration of 40 to 80 ms.

Spike and Wave Complex
type: Class
subclass of: Inter Ictal Pattern
comment: Spike-and-wave complexes (SWC) are spikes and waves that occur repititively (in series) and do not fulfill the criteria for more specific epileptiform patterns such as slow spike-and-wave complexes or 3-Hz spike-and-wave complexes.
label: Spike-and-Wave Complex

3-Hz Spike-and-Wave Complex
type: Class
subclass of: Spike and Wave Complex
comment: 3-Hz spike-and-wave complexes (3 SWC) refer to the bursts of spike-and-wave complexes with a regular repitition rate of 3 to 5.5 Hz.

Spindle Stupor
type: Class
subclass of: Special Pattern
comment: Spindle coma (SC) / Spindle stupor (SS) refers to an EEG recording of coma where the record is like that of a typical stage II sleep pattern

Spontaneous Seizure
type: Class
subclass of: Paroxysmal Event

SE
type: Class
subclass of: Paroxysmal Event
subclass of: Restriction
  on property: isCausedBy
  some values from: Temperature Induced Seizure
comment: A paroxysmal event that is "continuous, unremitting seizure lasting longer than 5 minutes".
label: Status Epilepticus

ST
type: Class
subclass of: Ictal Pattern
comment: Status pattern (EEG ST) refers to a continous EEG seizure pattern of frequent recurring EEG seizure patterns without return to normal background activity.
label: Status Pattern

Status Semiology
type: Class
subclass of: Ictal Pattern

Stavzor
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 804548

Stelazine
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 227572

Inducing Factor
type: Class
subclass of: Independent Continuant
label: InducingFactor
label: Precipitating Factor
label: Provoking Factor
label: Trigger

Stimulus Induced Seizure
type: Class
subclass of: Paroxysmal Event
subclass of: Restriction
  on property: isProvokedBy
  some values from: Inducing Factor
label: TriggeredSeizure

Stimulus Preceding Negativity
type: Class
subclass of: Scalp Recorded ERP Extracted Pattern

Stiripentol
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Diacomit
comment: Anti seizure medication
comment: Antiepileptic drug
see also: RxCUI 2054968

Stop Lost
type: Class
subclass of: "Molecular consequence represents effects on protein products from the alterations in the coding nucleotide sequence. " (https://www.ncbi.nlm.nih.gov/variation/docs/glossary/)
label: Stop Lost Variant
label: stop_lost

Medial part of gyri orbitales
type: Class
subclass of: Gyrus of frontal lobe
label: Rectal gyrus
label: Rectus gyrus

Strattera
type: Class
subclass of: Drug Brand Name
see also: RxCUI 358330

SIH
type: Class
subclass of: Model System Anxiety Scale
label: Stress-induced hyperthermia

Right Hemispheric Stroke
type: Class
subclass of: Structural Cause

Structural Cause
type: Class
subclass of: Aetiology

Venous Angioma
type: Class
subclass of: Vascular Malformation

Sub Cellular Structure
type: Class
subclass of: Anatomical Structure

Sub Clinical Episode
type: Class
subclass of: Non-Epileptic Seizure

Subclinical Status
type: Class
subclass of: SE

Subarachnoid (aneurysmal) Hemorrhage
type: Class
subclass of: Cerebral Hemorrhage

SREDA
type: Class
subclass of: Rhythmic Benign Variant
comment: Subclinical rhythmic non-epileptiform electrographic discharges in adults (SREDA) consists of mixed-frequency components in the delta and theta frequency ranges that evolve into a rhythmic pattern consisting of sharp-contoured components of 5-7 Hz.
label: Subclinical Rhythmic Electrographic Discharges in Adult

SEGA
type: Class
subclass of: Other Astrocytic Tumor
subclass of: Restriction
  on property: hasAssociatedMutationIn
  some values from: Class
    union of: Tuberous sclerosis complex subunit 1
    union of: Tuberous sclerosis complex subunit 2
label: Subependymal Giant Cell Astrocytoma

Subiculum hippocampi
type: Class
subclass of: Segment of gyrus of limbic lobe

Substance Abuse
type: Class
subclass of: Metabolic Cause

Subventricular nodular heterotopia
type: Class
subclass of: Nodular Heterotopias

SIDS
type: Class
subclass of: Premature Mortality
label: Sudden Infant Death Syndrome

SUDEP
type: Class
subclass of: Premature Mortality
subclass of: Restriction
  on property: isCausedBy
  some values from: Class
    union of: Bilateral Seizure
    union of: Epileptic Seizure
    union of: Focal Seizure
    union of: Generalized Seizure
label: Sudden Unexpected Death in Epilepsy

SUDY
type: Class
subclass of: Premature Mortality
label: Sudden Unexpected Death in Young

Marginal gyrus
type: Class
subclass of: Gyrus of frontal lobe
label: Superior frontal convolution
label: Superior frontal gyrus

Superior temporal gyrus
type: Class
subclass of: TemporalLobeGyrus

Supplementary Motor Area Epilepsy
type: Class
subclass of: Mesial Frontal Epilepsy

Symbyax
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 405343

Symptomatogenic Zone
type: Class
subclass of: EpilepsyZone
comment: Area of cortex which when activated by an epileptiform discharge produces the initial ictal symptomatology.

Synaptophysin antigen
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: isUsedForMarkingCellularPattern
  some values from: Class
    intersection of: Balloon Cell
    intersection of: Dysmorphic Neurons

Synonymous
type: Class
subclass of: "Molecular consequence represents effects on protein products from the alterations in the coding nucleotide sequence. " (https://www.ncbi.nlm.nih.gov/variation/docs/glossary/)
label: Synonymous Variant
label: missense_variant

TBC1 domain family member 24
type: Class
subclass of: Gene

T Cell
type: Class
subclass of: Lymphocyte
label: T lymphocyte
label: T-Cell

trafficking protein particle complex 4
type: Class
subclass of: Gene

trafficking protein particle complex 6B
type: Class
subclass of: Gene

transient receptor potential cation channel subfamily M member 1
type: Class
subclass of: Gene

Tuberous sclerosis complex subunit 1
type: Class
subclass of: Gene

Tuberous sclerosis complex subunit 2
type: Class
subclass of: Gene

thyroid stimulating hormone receptor
type: Class
subclass of: Gene

tetratricopeptide repeat domain 21B
type: Class
subclass of: Gene

Tachycardic Seizure
type: Class
subclass of: Autonomic Seizure

TST
type: Class
subclass of: Model System Depression Scale
label: Tail suspension test

TPT
type: Class
subclass of: Model System Depression Scale
label: Taste preference test

Tegretol®
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 203029
comment: Treats different types of seizures. Also used to treat nerve pain and bipolar disorder, also known as manic-depressive illness.

Tegretol XR®
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 152408
comment: Used to treat seizures and nerve pain such as trigeminal neuralgia and diabetic neuropathy. Also used to treat bipolar disorder.

Telencephalon
type: Class
subclass of: Forebrain Segment
subclass of: Restriction
  on property: regional part of
  some values from: Forebrain
comment: Organ component of neuraxis that has as its parts the cerebral cortex, cerebral white matter, basal ganglia, septum and fornix, as well as subcortical gray and white matter structures. There is only one telencephalon.

Basal Ganglion of Telencephalon
type: Class
subclass of: Ganglion of Neuraxis

Telencephalon Neural Tissue
type: Class
subclass of: Brain Neural Tissue Segment
subclass of: Restriction
  on property: regional part of
  some values from: Forebrain Neural Tissue
subclass of: Restriction
  on property: isConstitutionalPartOf
  some values from: Telencephalon
comment: Fmaid 268525

Telencephalon Zone
type: Class
subclass of: Neuraxis Zone

Teleopsia Status
type: Class
subclass of: Visual Illusion Status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Temperature Induced Seizure
type: Class
subclass of: Stimulus Induced Seizure
label: Temperature provoked seizure

Temporal 10-10 System
type: Class
subclass of: 10-10 System

Temporal Fossa
type: Class
subclass of: Space of Compartment of Head

Temporal Intermittent Rhythmic Delta Activity
type: Class
subclass of: Slow Activity
subclass of: Restriction
  on property: isLocatedAt
  some values from: Temporal

Temporal
type: Class
subclass of: CerebralHemisphereLobe
comment: Temporal lobe is the ventrolateral lobe of five lobes comprising each cerebral hemisphere. It is bounded dorsally by the lateral fissure and posteriorly by an arbitrary border shared with the occipital lobe. (source: FMA)

Temporal Lobe Epilepsy
type: Class
subclass of: Single Focal Epilepsy

Temporal Operculum
type: Class
subclass of: Telencephalon Zone
label: Temporo-Opercular

Temporal Plus Epilepsy
type: Class
subclass of: Single Focal Epilepsy

Temporal Pole
type: Class
subclass of: Telencephalon Zone
label: Temporal-Polar

Anterior Temporal Epilepsy
type: Class
subclass of: Temporal Lobe Epilepsy
label: AnteriorTemporalEpilepsy
label: Temporal Pole Epilepsy

Temporal Slow Activity
type: Class
subclass of: Normal EEG Pattern
comment: Temporal slow activity refers to the irregular slow activity coming from the temporal regions, occuring with increasing age.

Temporo Insular Epilepsy
type: Class
subclass of: Temporal Plus Epilepsy

Temporo Occipital Epilepsy
type: Class
subclass of: Temporal Plus Epilepsy

Temporo Opercular Epilepsy
type: Class
subclass of: Temporal Plus Epilepsy
label: Temporo Sylvian Epilepsy
label: TemporoSylvian_Epilepsy

Temporo Orbito Frontal Epilepsy
type: Class
subclass of: Temporal Plus Epilepsy

Temporo Parietal Epilepsy
type: Class
subclass of: BiLobar Epilepsy

Terminal apnea
type: Class
subclass of: Apnea

Tetrabenazine
type: Class
subclass of: Drug Ingredient
comment: Antidepressant Drug
see also: RxCUI 10390

Thermal Seizure
type: Class
subclass of: Somatosensory Aura

Thermal Status
type: Class
subclass of: Somatosensory Aura Status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Theta Activity
type: Class
subclass of: Normal EEG Pattern
comment: Theta activity refers to activity with a frequency range of 4 to 8 Hz.

Theta Coma
type: Class
subclass of: Special Pattern
comment: Theta coma (TC) / Theta stuport (TS) refers to predominance of theta waves in a comatose/stuporous patient.

Theta Stupor
type: Class
subclass of: Special Pattern
comment: Theta coma (TC) / Theta stuport (TS) refers to predominance of theta waves in a comatose/stuporous patient.

Thioridazine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Mellaril
    union of: Mellaril-S
comment: Antidepressant Drug
is defined by: Treats the symptoms of schizophrenia.
see also: RxCUI 10502

Thiothixene
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Navane
    union of: Noxene
comment: Antidepressant Drug
see also: RxCUI 10510

Third Toe
type: Class
subclass of: Toe

3CH
type: Class
subclass of: Model System Autism Scale
label: Three-chamber test

Three Dimensional Cartesian Spatial Coordinate Datum
type: Class
subclass of: Cartesian Spatial Coordinate Datum

Platelet
type: Class
subclass of: Non-Nucleated Cell

Tiagabine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: tiagabine hydrochloride
subclass of: Restriction
  on property: hasTradename
  some values from: Gabitril®
comment: Anti seizure medication
comment: Antiepileptic Drug
is defined by: Controls partial seizures when used in combination with other medicines. This medicine is an anticonvulsant.
see also: RxCUI 31914

tiagabine hydrochloride
type: Class
subclass of: Precise Drug Ingredient
see also: RxCUI 236875

Time Unit
type: Class
subclass of: Measurement Unit
comment: Similar to term defined in the Units Ontology.

Todd's Paralysis
type: Class
subclass of: Lateralizing Sign

Tofranil
type: Class
subclass of: Drug Brand Name
see also: RxCUI 6716

Tofranil-PM
type: Class
subclass of: Drug Brand Name
see also: RxCUI 220334

Tongue
type: Class
subclass of: Heterogeneous Cluster
comment: The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech[GO]

Tonic Clonic Episode
type: Class
subclass of: Simple Motor Episode

ConvulsiveMotorSeizure
type: Class
subclass of: Simple Motor Seizure
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Generalized Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Tonic-clonic seizures are typical seizures seen in patients with generalized epilepsy and consist of an initial tonic phase during which the the body stiffens followed by a phase in which the body jerks rhythmically or semi-rhythmically.
comment: Unknown Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
label: Tonic-clonic Seizure

Tonic Clonic Status
type: Class
subclass of: SimpleMotorStatus
comment: Convulsive status epilepticus (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Generalized Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Unknown Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Tonic Episode
type: Class
subclass of: Simple Motor Episode

ConvulsiveMotorSeizure
type: Class
subclass of: Simple Motor Seizure
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Generalized Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Tonic seizures consist of sustained muscle contractions usually lasting more than 5 to 10 seconds.
comment: Unknown Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
label: Generalized Tonic Seizure
label: Tonic Seizure

Tonic Seizure End
type: Class
subclass of: ConvulsiveMotorSeizure

Onset of Generalized Tonic Phase
type: Class
subclass of: ConvulsiveMotorSeizure
label: Tonic Seizure Onset

Tonic Status
type: Class
subclass of: SimpleMotorStatus
comment: Tonic status (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Topamax®
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 220343
comment: Helps control and prevent certain kinds of seizures. Also prevents migraine headaches in adults.

Topiragen
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 901323

Topiramate
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Qsymia
    union of: Topamax®
    union of: Topiragen
comment: Antiepileptic Drug
comment: Antiseizure Medication
is defined by: Helps control and prevent certain kinds of seizures. Also prevents migraine headaches in adults.
see also: RxCUI 38404

Transcription Factor
type: Class
subclass of: Protein Function
comment: "Transcription factors are a diverse group of proteins that bind to DNA at specific promoter or enhancer regions. They also bind to DNA-associated proteins to initiate, stimulate, inhibit or terminate transcription. The proteins are often physically associated in a preinitiation complex and contain structural motifs." (National Cancer Institute Thesaurus)

SRY-boxTranscriptionFactor1
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: Transcription Factor
label: Transcription Factor SOX-1

Transverse frontopolar gyrus
type: Class
subclass of: Gyrus of frontal lobe

Heschl gyrus
type: Class
subclass of: TemporalLobeGyrus
label: Heschl's gyrus
label: Transverse temporal gyrus

Traumatic Brain Injury
type: Class
subclass of: Structural Cause

Therapy
type: Class
subclass of: Clinical Care Management

Trifluoperazine
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Stelazine
comment: Antidepressant Drug
is defined by: Treats psychotic disorders and anxiety. Sometimes given for nausea and vomiting caused by chemotherapy. Belongs to a class of drugs called phenothiazines.
see also: RxCUI 10800

Triflupromazine
type: Class
subclass of: Drug Ingredient
comment: Antidepressant Drug
is defined by: Triflupromazine is an antipsychotic medication of the phenothiazine class. Among different effects of triflupromazine indication for use of this drug is severe emesis. Due to its potential side effects it is not gold standard in antiemetic therapy.
see also: RxCUI 10805

Trilafon
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 202730

Trileptal®
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 261680
comment: Used alone or together with other medicines to treat seizures caused by epilepsy in adults and children 2 years of age and older.

Triphasic Wave
type: Class
subclass of: Special Pattern
comment: Triphasic waves (TW) refer to high amplitude (> 70 uV) positive sharp transients which are preceded and followed by relatively low-amplitude negative waves.

Trunk
type: Class
subclass of: Subdivision of Body Proper
comment: Subdivision of body proper, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the ribcage, thoracic and lumbar vertebral column, sacrum and coccyx, it is partially surrounded by skin of trunk. Examples: There is only one trunk. (source: FMA)

Tuber Cinereum
type: Class
subclass of: Diencephalon Zone
subclass of: Restriction
  on property: regional part of
  some values from: Intermediate Hypothalamic Region
comment: The tuber cinereum is a hollow eminence of gray matter situated between the mammilary bodies and the optic chiasm. The tuber cinereum is part of the hypothalamus.

Tuberous Sclerosis
type: Class
subclass of: Malformation of Cortical Development

Two Dimensional Cartesian Spatial Coordinate Datum
type: Class
subclass of: Cartesian Spatial Coordinate Datum

ANNA1Antibody
type: Class
subclass of: Biological Substance
label: AntiRiAntibody
label: Type 1 Anti Neuronal Nuclear Antibody

ANNA2Antibody
type: Class
subclass of: Biological Substance
label: AntiHuAntibody
label: Type 2 Anti Neuronal Nuclear Antibody

ANNA3
type: Class
subclass of: Biological Substance
label: Type 3 Anti Neuronal Nuclear Antibody

Typical Dialeptic Episode
type: Class
subclass of: Dialeptic Episode

Typical Dialeptic Seizure
type: Class
subclass of: Dialeptic Seizure

Typical Dialeptic Status
type: Class
subclass of: Dialeptic Status
comment: Atypical (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Generalized Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Versio
comment: Impaired Consciousness (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Typical (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Versio

ubiquitination factor E4A
type: Class
subclass of: Gene

USV-A
type: Class
subclass of: Model System Autism Scale
label: Ultrasonic vocalizations-adults

USV-P
type: Class
subclass of: Model System Autism Scale
label: Ultrasonic vocalizations-pups

Unconditioned stimulus
type: Class
subclass of: Inducing Factor

Underlying Disorder
type: Class
subclass of: Premature Mortality

Undetermined Epilepsy
type: Class
subclass of: Epilepsy

Undifferentiated attention deficit disorder
type: Class
subclass of: ADHD

Unilateral Automatism
type: Class
subclass of: Lateralizing Sign
subclass of: Restriction
  on property: isLocatedAt
  some values from: Class
    union of: Left Hand
    union of: Right Hand

Unilateral Epileptic Spasm
type: Class
subclass of: Lateralizing Sign

Unknown Cause
type: Class
subclass of: Aetiology

Unknown
type: Class
subclass of: Seizure Frequency Category
comment: LA4489-6 (LOINC Code)
label: Unknown Seizure Frequency

Urinary Seizure
type: Class
subclass of: Autonomic Seizure

Vaccination Induced Hyperthermia
type: Class
subclass of: Body Temperature Stimulus

Vagal apnea
type: Class
subclass of: Apnea

Vagus Nerve Stimulation
type: Class
subclass of: Neurostimulation Therapy

Valproate
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Class
    intersection of: Divalproex Sodium
    intersection of: Magnesium Valproate
    intersection of: sodium valproate
    intersection of: Valproic Acid
subclass of: Restriction
  on property: hasTradename
  some values from: Class
    union of: Depacon
    union of: Depakene®
    union of: Depakote®
    union of: Depakote ER®
    union of: Epilim
    union of: Stavzor
comment: Anti seizure medication
comment: Antiepileptic Drug
is defined by: Used for controlling certain types of seizures in the treatment of epilepsy in patients who are unable to take the oral form of valproate.
see also: RxCUI 40254

Valproic Acid
type: Class
subclass of: Precise Drug Ingredient
comment: Anti seizure medication
comment: Treats seizures (epilepsy). Also used to treat mood disorders and prevent migraine headaches. This medicine is an anticonvulsant.

Vanatrip
type: Class
subclass of: Drug Brand Name
see also: RxCUI 220736

Allele ID: 59810
type: Class
subclass of: DEPDC5 SequenceVariant
subclass of: Restriction
  on property: hasVariantConsequence
  some values from: Nonsense
subclass of: Restriction
  on property: hasPhenotype
  some values from: Familial Focal Epilepsy With Variable Foci
subclass of: Restriction
  on property: hasSequenceVariant
  some values from: SNV
comment: Variant Detail (from ClinVar): NM_001242897.2(DEPDC5):c.1663C>T (p.Arg555Ter)

Allele ID: 59812
type: Class
subclass of: DEPDC5 SequenceVariant
subclass of: Restriction
  on property: hasVariantConsequence
  some values from: Nonsense
subclass of: Restriction
  on property: hasPhenotype
  some values from: Familial Focal Epilepsy With Variable Foci
subclass of: Restriction
  on property: hasSequenceVariant
  some values from: SNV
comment: Variant Detail (from ClinVar): NM_001242897.2(DEPDC5):c.3807G>A (p.Trp1269Ter)

Allele ID: 59814
type: Class
subclass of: DEPDC5 SequenceVariant
subclass of: Restriction
  on property: hasVariantConsequence
  some values from: Nonsense
subclass of: Restriction
  on property: hasPhenotype
  some values from: Familial Focal Epilepsy With Variable Foci
subclass of: Restriction
  on property: hasSequenceVariant
  some values from: SNV
comment: Variant Detail (from ClinVar): NM_001242897.2(DEPDC5):c.715C>T (p.Arg239Ter)

Allele ID: 59815
type: Class
subclass of: DEPDC5 SequenceVariant
subclass of: Restriction
  on property: hasVariantConsequence
  some values from: Nonsense
subclass of: Restriction
  on property: hasPhenotype
  some values from: Familial Focal Epilepsy With Variable Foci
subclass of: Restriction
  on property: hasSequenceVariant
  some values from: SNV
comment: Variant detail (from ClinVar): NM_001242897.2(DEPDC5):c.982C>T (p.Arg328Ter)

Allele ID: 59809
type: Class
subclass of: DEPDC5 SequenceVariant
subclass of: Restriction
  on property: hasVariantConsequence
  some values from: Nonsense
subclass of: Restriction
  on property: hasPhenotype
  some values from: Familial Focal Epilepsy With Variable Foci
subclass of: Restriction
  on property: hasSequenceVariant
  some values from: SNV
comment: Variant detail (from ClinVar): NM_001242897.2(DEPDC5):c.21C>G (p.Tyr7Ter)

Allele ID: 75270
type: Class
subclass of: GABRG2 SequenceVariant
subclass of: Restriction
  on property: hasVariantConsequence
  some values from: Missense
subclass of: Restriction
  on property: hasPhenotype
  some values from: Early Infantile Epileptic Encephalopathy With Suppression Bursts
subclass of: Restriction
  on property: hasVariantType
  some values from: SNV
comment: Variant detail (from ClinVar): NM_198903.2(GABRG2):c.1088G>A (p.Arg363Gln)

VariationID60767
type: Class
subclass of: SCN1B SequenceVariant
subclass of: Restriction
  on property: hasVariantConsequence
  some values from: Missense
subclass of: Restriction
  on property: hasPhenotype
  some values from: Class
    union of: Early Infantile Epileptic Encephalopathy With Suppression Bursts
    union of: GEFS+
subclass of: Restriction
  on property: hasVariantType
  some values from: SNV
comment: Variant Detail (from ClinVar): NM_001037.5(SCN1B):c.254G>A (p.Arg85His)
is defined by: Allele ID: 75309

Allele ID: 79392
type: Class
subclass of: SCN1A SequenceVariant
subclass of: Restriction
  on property: hasVariantConsequence
  some values from: Missense
subclass of: Restriction
  on property: hasPhenotype
  some values from: Dravet Syndrome
subclass of: Restriction
  on property: hasVariantType
  some values from: SNV
comment: Variation Detail (from ClinVar): NM_001165963.4(SCN1A):c.1072C>A (p.Pro358Thr)

Allele ID: 79394
type: Class
subclass of: SCN1A SequenceVariant
subclass of: Restriction
  on property: hasVariantConsequence
  some values from: Missense
subclass of: Restriction
  on property: hasPhenotype
  some values from: Class
    union of: Dravet Syndrome
    union of: GEFS+
subclass of: Restriction
  on property: hasVariantType
  some values from: SNV
comment: Variant detail (from ClinVar): NM_001165963.4(SCN1A):c.1130G>A (p.Arg377Gln)

Allele ID: 79396
type: Class
subclass of: SCN1A SequenceVariant
subclass of: Restriction
  on property: hasVariantConsequence
  some values from: Missense
subclass of: Restriction
  on property: hasPhenotype
  some values from: Class
    union of: Dravet Syndrome
    union of: Early Infantile Epileptic Encephalopathy With Suppression Bursts
subclass of: Restriction
  on property: hasVariantType
  some values from: SNV
comment: Variation Detail (from ClinVar): NM_001165963.4(SCN1A):c.1177C>A (p.Arg393Ser)

Allele ID: 79397
type: Class
subclass of: SCN1A SequenceVariant
subclass of: Restriction
  on property: hasVariantConsequence
  some values from: Missense
subclass of: Restriction
  on property: hasPhenotype
  some values from: Class
    union of: Dravet Syndrome
    union of: Early Infantile Epileptic Encephalopathy With Suppression Bursts
subclass of: Restriction
  on property: hasVariantType
  some values from: SNV
comment: Variation Detail (from ClinVar): NM_001165963.4(SCN1A):c.1177C>T (p.Arg393Cys)

Allele ID: 79398
type: Class
subclass of: SCN1A SequenceVariant
subclass of: Restriction
  on property: hasVariantConsequence
  some values from: Missense
subclass of: Restriction
  on property: hasVariantType
  some values from: SNV
subclass of: Restriction
  on property: hasVariantType
  some values from: Class
    union of: Dravet Syndrome
    union of: Early Infantile Epileptic Encephalopathy With Suppression Bursts
comment: Variation Detail (from ClinVar): NM_001165963.4(SCN1A):c.1178G>A (p.Arg393His)

Allele ID: 79404
type: Class
subclass of: SCN1A SequenceVariant
subclass of: Restriction
  on property: hasVariantConsequence
  some values from: Missense
subclass of: Restriction
  on property: hasPhenotype
  some values from: Class
    union of: Dravet Syndrome
    union of: Generalized Epilepsy
subclass of: Restriction
  on property: hasVariantType
  some values from: SNV
comment: Variant Details (from ClinVar): NM_001165963.4(SCN1A):c.1876A>G (p.Ser626Gly)

Allele ID: 79412
type: Class
subclass of: SCN1A SequenceVariant
subclass of: Restriction
  on property: hasVariantConsequence
  some values from: Missense
subclass of: Restriction
  on property: hasPhenotype
  some values from: Class
    union of: Dravet Syndrome
    union of: Early Infantile Epileptic Encephalopathy With Suppression Bursts
    union of: GEFS+
subclass of: Restriction
  on property: hasVariantType
  some values from: SNV
comment: Variation Detail (from ClinVar): NM_001165963.4(SCN1A):c.251A>G (p.Tyr84Cys)

Allele ID: 79415
type: Class
subclass of: SCN1A SequenceVariant
subclass of: Restriction
  on property: hasVariantConsequence
  some values from: Missense
subclass of: Restriction
  on property: hasPhenotype
  some values from: Class
    union of: Dravet Syndrome
    union of: Early Infantile Epileptic Encephalopathy With Suppression Bursts
    union of: GEFS+
subclass of: Restriction
  on property: hasVariantType
  some values from: SNV
comment: Variation Detail (from ClinVar): NM_001165963.4(SCN1A):c.2837G>A (p.Arg946His)

Allele ID: 94262
type: Class
subclass of: SPAG1 SequenceVariant
subclass of: Restriction
  on property: hasVariantConsequence
  some values from: Nonsense
subclass of: Restriction
  on property: hasPhenotype
  some values from: ADNFLE
subclass of: Restriction
  on property: hasVariantType
  some values from: SNV
comment: Variation Detail (from ClinVar): NM_003114.4(SPAG1):c.679G>T (p.Glu227Ter)

Allele ID: 94263
type: Class
subclass of: SPAG1 SequenceVariant
subclass of: Restriction
  on property: hasVariantConsequence
  some values from: Nonsense
subclass of: Restriction
  on property: hasPhenotype
  some values from: ADNFLE
subclass of: Restriction
  on property: hasVariantType
  some values from: SNV
comment: Variation Detail (from ClinVar): NM_172218.2(SPAG1):c.2014C>T (p.Gln672Ter)

Allele ID: 94304
type: Class
subclass of: GRIN2A SequenceVariant
subclass of: Restriction
  on property: hasVariantConsequence
  some values from: Splice-DA
subclass of: Restriction
  on property: hasPhenotype
  some values from: Benign childhood epilepsy with centrotemporal spikes
subclass of: Restriction
  on property: hasVariantType
  some values from: SNV
comment: Variation Detail (from ClinVar): NM_001134407.3(GRIN2A):c.1007+1G>A

Allele ID: 94305
type: Class
subclass of: GRIN2A SequenceVariant
subclass of: Restriction
  on property: hasVariantConsequence
  some values from: Missense
subclass of: Restriction
  on property: hasPhenotype
  some values from: Focal Epilepsy
subclass of: Restriction
  on property: hasVariantType
  some values from: SNV
comment: Variation Details (from ClinVar): NM_001134407.3(GRIN2A):c.2T>C (p.Met1Thr)

Allele ID: 94306
type: Class
subclass of: GRIN2A SequenceVariant
subclass of: Restriction
  on property: hasVariantConsequence
  some values from: Nonsense
subclass of: Restriction
  on property: hasPhenotype
  some values from: Focal Epilepsy
subclass of: Restriction
  on property: hasVariantType
  some values from: SNV
comment: Variation Details (from ClinVar): NM_001134407.3(GRIN2A):c.2829C>G (p.Tyr943Ter)

Allele ID: 94308
type: Class
subclass of: GRIN2A SequenceVariant
subclass of: Restriction
  on property: hasVariantConsequence
  some values from: Splice-DA
subclass of: Restriction
  on property: hasPhenotype
  some values from: Focal Epilepsy
subclass of: Restriction
  on property: hasVariantType
  some values from: SNV
comment: Variation Details (from ClinVar): NM_001134407.3(GRIN2A):c.1123-2A>G

Allele ID: 94309
type: Class
subclass of: GRIN2A SequenceVariant
subclass of: Restriction
  on property: hasVariantConsequence
  some values from: Missense
subclass of: Restriction
  on property: hasPhenotype
  some values from: Focal Epilepsy
subclass of: Restriction
  on property: hasVariantType
  some values from: SNV
comment: Variation Detail (from ClinVar): NM_001134407.3(GRIN2A):c.1553G>A (p.Arg518His)

Allele ID: 94310
type: Class
subclass of: GRIN2A SequenceVariant
subclass of: Restriction
  on property: hasVariantConsequence
  some values from: Missense
subclass of: Restriction
  on property: hasPhenotype
  some values from: Focal Epilepsy
subclass of: Restriction
  on property: hasVariantType
  some values from: SNV
comment: Variation Detail (from ClinVar): NM_001134407.3(GRIN2A):c.1954T>G (p.Phe652Val)

Allele ID: 94311
type: Class
subclass of: GRIN2A SequenceVariant
subclass of: Restriction
  on property: hasVariantConsequence
  some values from: Nonsense
subclass of: Restriction
  on property: hasPhenotype
  some values from: Focal Epilepsy
subclass of: Restriction
  on property: hasVariantType
  some values from: SNV
comment: Variation Detail (from ClinVar): NM_001134407.3(GRIN2A):c.2041C>T (p.Arg681Ter)

Variation Type
type: Class
subclass of: Genomic Variation

Vascular Malformation
type: Class
subclass of: Structural Cause

VIP
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: Neuro Modulator
subclass of: Restriction
  on property: hasFunction
  some values from: Protein
label: Vasoactive Intestinal Peptide

Vasoactive Intestinal Peptide Expressing Interneuron
type: Class
subclass of: Interneuron
subclass of: Restriction
  on property: isMarkedBy
  some values from: VIP receptor

VIP receptor
type: Class
subclass of: Biological Substance
label: Vasoactive Intestinal Peptide Receptor

Vasomotor Seizure
type: Class
subclass of: Autonomic Seizure

Ventricular Fibrillation
type: Class
subclass of: Arrhythmia

Ventricular Myocyte
type: Class
subclass of: Heart Myocyte

Ventricular Myocyte Cell Culture
type: Class
subclass of: Cell Culture

Versacloz
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 1369826

Versive Episode
type: Class
subclass of: Simple Motor Episode

Versive Seizure
type: Class
subclass of: Simple Motor Seizure
comment: Motor (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Versive seizures consist of a sustained, unnatural turning of the eyes and head to one side.

Versive Status
type: Class
subclass of: SimpleMotorStatus
comment: Adversive status (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Vertical
type: Class
subclass of: Anatomical Coordinate

Vigabatrin
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Sabril
comment: Anti seizure medication
comment: Antiepileptic Drug
is defined by: Treats seizures (epilepsy). This medicine is an anticonvulsant.
see also: RxCUI 14851

Vimpat
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 809979
comment: Used with other medicines to treat partial seizures in patients who have epilepsy.

Visual Agnosia
type: Class
subclass of: Visual Aura

Visual Agnosia Status
type: Class
subclass of: Visual Aura Status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Visual Aura
type: Class
subclass of: Non-Specific Aura
comment: Sensory (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Visual auras consists of visual hallucinations or illusions.

Visual Aura Status
type: Class
subclass of: Aura status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Visual Hallucination
type: Class
subclass of: Visual Aura

Visual Hallucination Status
type: Class
subclass of: Visual Aura Status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Visual Illusion
type: Class
subclass of: Visual Aura

Visual Illusion Status
type: Class
subclass of: Visual Aura Status
comment: Focal Onset (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)
comment: Non-convulsive status epilepticus without coma (mapping reference: ILAE 2017 Classification of Seizure Types Expanded Version)

Visual Occipital N100
type: Class
subclass of: Scalp Recorded ERP Extracted Pattern

Visual Occipital P100
type: Class
subclass of: Scalp Recorded ERP Extracted Pattern

Visual Posterotemporal N200
type: Class
subclass of: Scalp Recorded ERP Extracted Pattern

VGKC Associated Protein
type: Class
subclass of: Protein Function
comment: "A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential" (Gene Ontology)
label: Voltage-gated Potassium Channel Associated Protein
label: voltage-gated potassium channel complex

VGCCTypeNAssociatedEncephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
subclass of: Restriction
  on property: hasAssociatedAntigen
  some values from: N_Type Voltage-gated calcium channel
label: Voltage Gated Calcium Channel Type N Associated Encephalitis

VGCCTypePQAssociatedEncephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
subclass of: Restriction
  on property: hasAssociatedAntigen
  some values from: P_Q_Type Voltage Gated Calcium Channel
label: Voltage Gated Calcium Channel Type PQ Associated Encephalitis

Voltage Gated Potassium Channel
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: Ion Channel
label: Voltage-gated potassium channel

VGKCAssociatedEncephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
subclass of: Restriction
  on property: hasAssociatedAntigen
  some values from: Voltage Gated Potassium Channel
label: Voltage Gated Potassium Channel Associated Encephalitis

Vyvanse
type: Class
subclass of: Drug Brand Name
see also: RxCUI 711043

WD repeat domain 37
type: Class
subclass of: Gene

Weekly Seizure
type: Class
subclass of: Seizure Frequency Category
comment: LA32855-1 (LOINC Code)
comment: Weekly but not daily (i.e., 1-3 per week)

Wellbutrin
type: Class
subclass of: Drug Brand Name
see also: RxCUI 42568

West Syndrome
type: Class
subclass of: Generalized Epilepsy

White matter lesion
type: Class
subclass of: Cortical Dysplasia

Wicket Spike
type: Class
subclass of: Epileptiform Benign Variant
comment: Wicket spikes consist of intermittent trains or clusters of monophasic arciform waveform or single spike-like waveform that look like a Greek mu or wicket.

WHO Grading
type: Class
subclass of: Measurement Unit
label: World Health Organization Grading

WHO grade I
type: Class
subclass of: WHO Grading
label: WHO_I
label: World Health Organization I

WHO_II
type: Class
subclass of: WHO Grading
label: World Health Organization II

WHO_III
type: Class
subclass of: WHO Grading
label: World Health Organization III

WHO_IV
type: Class
subclass of: WHO Grading
label: World Health Organization IV

Xcopri
type: Class
subclass of: Drug Brand Name
see also: RxCUI 2265696

Xenazine
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 594629

Yearly Seizure
type: Class
subclass of: Seizure Frequency Category
comment: At least once per year, but not every month (i.e., 10 or fewer in past 12 months)
comment: LA32857-7 (LOINC Code)

Zarontin®
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 202981
comment: Used for controlling absence epilepsy (previously known as petit mal seizures). It acts in the brain to reduce the number of absence seizures.

Zenzedi
type: Class
subclass of: Drug Brand Name
see also: RxCUI 1425332

Ziprasidone
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Geodon
comment: Antidepressant Drug
see also: RxCUI 115698

Zonalon
type: Class
subclass of: Drug Brand Name
see also: RxCUI 9801

Zonegran®
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 261708
comment: Treats partial seizures in adults with epilepsy. May be used together with other anti-seizure medicines. Belongs to a class of drugs called sulfonamides (sulfa drugs).

Zonisamide
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasTradename
  some values from: Zonegran®
comment: Anti seizure medication
comment: Antiepileptic Drug
is defined by: Treats partial seizures in adults with epilepsy. May be used together with other anti-seizure medicines. Belongs to a class of drugs called sulfonamides (sulfa drugs).
see also: RxCUI 39998

Zotepine
type: Class
subclass of: Drug Ingredient
comment: Antidepressant Drug
see also: RxCUI 40003

Ztalmy
type: Class
subclass of: Drug Brand Name
see also: RxCUI 2604695

Zuclopenthixol
type: Class
subclass of: Drug Ingredient
subclass of: Restriction
  on property: hasPreciseDrugIngredient
  some values from: Class
    intersection of: Zuclopenthixol Acetate
    intersection of: Zuclopenthixol Decanoate
    intersection of: Zuclopenthixol Dihydrochloride
comment: Antidepressant Drug
see also: RxCUI 114176

Zuclopenthixol Acetate
type: Class
subclass of: Precise Drug Ingredient
synonym: RxCUI 58338

Zuclopenthixol Decanoate
type: Class
subclass of: Precise Drug Ingredient
synonym: RxCUI 58339

Zuclopenthixol Dihydrochloride
type: Class
subclass of: Precise Drug Ingredient
synonym: RxCUI 102546

Zyban
type: Class
subclass of: Drug Brand Name
see also: RxCUI 227948

Zyprexa
type: Class
subclass of: Drug Brand Name
synonym: RxCUI 135423

GABA A Receptor
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: Neurotransmitter receptor
label: GABA-A Receptor Antagonists

GABAARAssociatedEncephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
subclass of: Restriction
  on property: hasAssociatedAntigen
  some values from: GABA A Receptor
label: γ Amino Butyric Acid A Receptor Associated Encephalitis

GABA B Receptor
type: Class
subclass of: Biological Substance
subclass of: Restriction
  on property: hasFunction
  some values from: Neurotransmitter receptor

GABABRAssociatedEncephalitis
type: Class
subclass of: Antibody-associated Encelphalitis
subclass of: Restriction
  on property: hasAssociatedAntigen
  some values from: GABA B Receptor
label: γ Amino Butyric Acid B Receptor Associated Encephalitis

10-10 System
type: Class
subclass of: Electrode Placement System

8-OH-DPAT-induced hypothermia
type: Class
subclass of: Model System Depression Scale
label: DPAT

Cytotoxic T Cell CD8+
type: Class
subclass of: T Cell

Gudden atrophy
type: Class
subclass of: Atrophy (morphologic abnormality)

Helper T Cell CD4+
type: Class
subclass of: T Cell

Continuant
type: Class
comment: "A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity." (Basic Formal Ontology)

Dependent Continuant
type: Class
subclass of: Continuant

Independent Continuant
type: Class
subclass of: Continuant

Occurrent
type: Class
subclass of: Thing
comment: "An occurrentis an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region." (Basic Formal Ontology)

Processual Entity
type: Class
subclass of: Occurrent

Spatial Region
type: Class
subclass of: Independent Continuant

Spatio Temporal Region
type: Class
subclass of: Processual Entity

Temporal Entity
type: Class
subclass of: Occurrent