format-version: 1.2 date: 01:12:2011 17:28 saved-by: midori auto-generated-by: OBO-Edit 2.1-rc3 default-namespace: fission_yeast_phenotype remark: svn version: $Revision$ ontology: fypo [Term] id: FYPO:0000001 name: phenotype def: "Any of the set of observable characteristics of an organism resulting from the interaction of its genotype with the environment." [PomBase:mah] creation_date: 2011-03-16T03:59:25Z [Term] id: FYPO:0000002 name: cell phenotype def: "A phenotype that is observed at the level of an individual cell." [PomBase:mah] is_a: FYPO:0000001 ! phenotype intersection_of: FYPO:0000001 ! phenotype intersection_of: inheres_in CL:0000000 created_by: midori creation_date: 2011-03-16T04:25:28Z [Term] id: FYPO:0000003 name: cell population phenotype def: "A phenotype that is observed at the level of a population of cells." [PomBase:mah] comment: note: differentium is population level, and may reflect observation conditions is_a: FYPO:0000001 ! phenotype created_by: midori creation_date: 2011-03-16T04:26:35Z [Term] id: FYPO:0000004 name: viability def: "A cell phenotype that consists of the cell's disposition to survive and develop normally." [PomBase:mah] is_a: FYPO:0000002 ! cell phenotype intersection_of: PATO:0000169 intersection_of: inheres_in CL:0000000 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000005 name: abnormal cell morphology alt_id: FYPO:0000019 def: "A cell phenotype characterized by altered cell morphology." [PomBase:mah] synonym: "cell morphology, misshapen cells" EXACT [PomBase:mah] is_a: FYPO:0000136 ! cellular structure phenotype created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000006 name: abnormal DNA damage checkpoint def: "A cell cycle checkpoint phenotype that affects the DNA damage checkpoint." [PomBase:mah] synonym: "DNA damage checkpoint defects" EXACT [PomBase:mah] is_a: FYPO:0000157 ! abnormal response to DNA damage stimulus is_a: FYPO:0000643 ! abnormal DNA integrity checkpoint intersection_of: PATO:0000001 intersection_of: inheres_in GO:0000077 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000007 name: abnormal S-phase DNA damage checkpoint alt_id: FYPO:0000195 def: "A cell cycle checkpoint phenotype that affects the S phase DNA damage checkpoint (also known as the intra-S phase DNA damage checkpoint)." [PomBase:mah] synonym: "abnormal intra-S DNA damage checkpoint" EXACT [] synonym: "DNA damage checkpoint defects, S-phase" EXACT [PomBase:mah] is_a: FYPO:0000006 ! abnormal DNA damage checkpoint intersection_of: PATO:0000001 intersection_of: inheres_in GO:0031573 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000008 name: abnormal meiotic recombination def: "A cellular process phenotype in which reciprocal meiotic recombination is abnormal." [PomBase:mah] synonym: "abnormal meiotic DNA recombination" EXACT [PomBase:mah] synonym: "abnormal reciprocal meiotic recombination" EXACT [PomBase:mah] synonym: "DNA recombination defects, meiotic" EXACT [PomBase:mah] synonym: "meiotic recombination: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000063 ! abnormal DNA recombination intersection_of: PATO:0000001 intersection_of: inheres_in GO:0007131 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000009 name: abnormal cell adhesion def: "A cellular process phenotype in which adhesion of a cell to a substrate or another cell is abnormal." [PomBase:mah] synonym: "adhesion defects" EXACT [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process intersection_of: PATO:0000001 intersection_of: inheres_in GO:0007155 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000010 name: cell-substrate adhesion abolished def: "A cell adhesion phenotype in which cells fail to adhere to a substrate." [PomBase:mah] is_a: FYPO:0000009 ! abnormal cell adhesion intersection_of: PATO:0001508 intersection_of: inheres_in GO:0031589 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000011 name: abnormal cell cycle progression alt_id: FYPO:0000406 def: "A cellular process phenotype in which a cell does not proceed normally through a cell cycle." [PomBase:mah] synonym: "abnormal cell-division cycle" EXACT [GO:0007049, PomBase:mah] synonym: "cell cycle defects" EXACT [PomBase:mah] synonym: "cell cycle progression: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000628 ! abnormal cellular process is_a: FYPO:0000631 ! cell cycle phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0007049 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000012 name: mitotic G2/M transition delay alt_id: FYPO:0000401 def: "A cell cycle phenotype in which the G2/M transition of the mitotic cell cycle takes place later than normal. The duration of G2 phase is thus longer than normal." [PomBase:mah] synonym: "cell cycle progression through the G2/M phase transition: delayed" EXACT [SGD:phenotype_annotation] synonym: "cell cycle, G2 delay" EXACT [PomBase:mah] synonym: "delayed cell cycle progression through mitotic G2/M phase transition" EXACT [] synonym: "G2 delay" EXACT [PomBase:mah] synonym: "increased G2 duration" EXACT [PomBase:mah] synonym: "mitotic cell cycle delay at G2/M transition" EXACT [PomBase:mah] is_a: FYPO:0000399 ! abnormal cell cycle progression through mitotic G2/M phase transition is_a: FYPO:0000409 ! delayed cell cycle progression intersection_of: PATO:0000001 intersection_of: inheres_in GO:0000086 intersection_of: qualifier PATO:0001542 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000013 name: T-shaped cells def: "A cell morphology phenotype in which a single cell grows in the form of the letter T. The cell usually septates perpendicular to the normal septation axis, and divides to form normal-shaped daughter cells." [PomBase:mah, PomBase:vw] synonym: "cell morphology, T shaped" EXACT [PomBase:mah] is_a: FYPO:0000005 ! abnormal cell morphology intersection_of: PATO:0001200 intersection_of: inheres_in CL:0000000 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000014 name: bottle-shaped cells def: "A cell morphology phenotype in which the cell tapers at one end to a diameter smaller than the other." [PomBase:mah] synonym: "cell morphology, bottle/skittle" EXACT [PomBase:mah] synonym: "skittle-shaped cells" EXACT [PomBase:mah] is_a: FYPO:0000005 ! abnormal cell morphology intersection_of: PATO:0002213 intersection_of: inheres_in CL:0000000 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000015 name: branched cells def: "A cell morphology phenotype in which a daughter cell grows from near, and at approximately a right angle to, the septum of the mother cell, resulting in the formation of a branched, septated cell. Cell division may give rise to branched or unbranched daughter cells." [PomBase:jh, PomBase:mah] synonym: "cell morphology, branched" EXACT [PomBase:mah] is_a: FYPO:0000005 ! abnormal cell morphology intersection_of: PATO:0000402 intersection_of: inheres_in CL:0000000 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000016 name: curved cells def: "A cell morphology phenotype in which cells are curved along the long axis." [PomBase:mah] synonym: "bent cells" EXACT [PomBase:mah] synonym: "cell morphology, curved" EXACT [PomBase:mah] is_a: FYPO:0000005 ! abnormal cell morphology intersection_of: PATO:0000406 intersection_of: inheres_in CL:0000000 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000017 name: elongated cells def: "A cell morphology phenotype in which cells are longer than normal." [PomBase:mah] synonym: "cell morphology, elongated cells" EXACT [PomBase:mah] is_a: FYPO:0000005 ! abnormal cell morphology intersection_of: PATO:0000573 intersection_of: inheres_in CL:0000000 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000018 name: elongated dumbbell morphology def: "A cell morphology phenotype in which a cell is shaped in the form of a dumbbell, i.e. having two connected, roughly spherical parts of approximately equal size." [PomBase:mah] synonym: "cell morphology, elongated dumbbell" EXACT [PomBase:mah] is_a: FYPO:0000005 ! abnormal cell morphology intersection_of: PATO:0000051 intersection_of: inheres_in CL:0000000 intersection_of: qualifier PATO:0000573 intersection_of: qualifier PATO:0001876 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000020 name: pear-shaped cells def: "A cell morphology phenotype in which a cell is shaped in the form of a pear." [PomBase:mah] comment: Discussing what this means; may rename. synonym: "cell morphology, pear shaped" EXACT [PomBase:mah] is_a: FYPO:0000005 ! abnormal cell morphology intersection_of: PATO:0002240 intersection_of: inheres_in CL:0000000 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000021 name: spheroid cells def: "A cell morphology phenotype in which a cell is shaped in the form of a spheroid. Spheroid cells are shorter than normal, and have approximately the same diameter as normal." [PomBase:mah] synonym: "cell morphology, round cells" RELATED [PomBase:mah] synonym: "cell morphology, rounded cells" RELATED [PomBase:mah] is_a: FYPO:0000005 ! abnormal cell morphology intersection_of: PATO:0001865 intersection_of: inheres_in CL:0000000 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000022 name: shmoos with long tips def: "A cell morphology phenotype in which a cell forms a mating projection with a longer tip than normal." [PomBase:mah] synonym: "cell morphology, shmoos with long tips" EXACT [PomBase:mah] synonym: "mating projections with long tips" EXACT [PomBase:mah] is_a: FYPO:0000357 ! abnormal shmoo morphology intersection_of: PATO:0000573 intersection_of: inheres_in GO:0043332 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000023 name: small cells def: "A cell morphology phenotype in which cells have an abnormally low volume." [PomBase:mah] is_a: FYPO:0000005 ! abnormal cell morphology intersection_of: PATO:0000596 intersection_of: inheres_in CL:0000000 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000024 name: stubby cells def: "A cell morphology phenotype in which the cell diameter is larger than normal and the cell length is shorter than normal." [PomBase:mah] synonym: "cell morphology, stubby cells" EXACT [PomBase:mah] is_a: FYPO:0000005 ! abnormal cell morphology intersection_of: PATO:0001653 intersection_of: inheres_in CL:0000000 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000025 name: swollen cells def: "A cell morphology phenotype in which a cell has a larger volume than normal." [PomBase:mah] synonym: "cell morphology, swollen cells" EXACT [PomBase:mah] is_a: FYPO:0000005 ! abnormal cell morphology intersection_of: PATO:0000595 intersection_of: inheres_in CL:0000000 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000026 name: abnormal cell polarity def: "A cellular process phenotype in which the establishment or maintenance of cell polarity is abnormal." [PomBase:mah] synonym: "abnormal establishment or maintenance of cell polarity" EXACT [PomBase:mah] synonym: "cell polarity defects" EXACT [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process intersection_of: PATO:0000001 intersection_of: inheres_in GO:0007163 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000027 name: abnormal cell wall def: "A cellular structure phenotype in which the cell wall is abnormal." [PomBase:mah] synonym: "cell wall defects" EXACT [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular structure intersection_of: PATO:0000001 intersection_of: inheres_in GO:0009277 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000029 name: abnormal chromosome segregation alt_id: FYPO:0000226 def: "A cellular process phenotype in which chromosome segregation is abnormal." [PomBase:mah] synonym: "centromere function defective" RELATED [PomBase:mah] synonym: "chromosome segregation defects" EXACT [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process intersection_of: PATO:0000001 intersection_of: inheres_in GO:0007059 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000030 name: abnormal chromosome congression def: "A cellular process phenotype in which chromosome congression is abnormal." [PomBase:mah] synonym: "chromosome segregation defects, chromosome congression" EXACT [PomBase:mah] is_a: FYPO:0000029 ! abnormal chromosome segregation intersection_of: PATO:0000001 intersection_of: inheres_in GO:0051310 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000031 name: abnormal conjugation def: "A cellular process phenotype in which conjugation is abnormal." [PomBase:mah] synonym: "abnormal conjugation with cellular fusion" EXACT [PomBase:mah] synonym: "conjugation defects" EXACT [PomBase:mah] is_a: FYPO:0000301 ! mating phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0000747 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000032 name: abnormal cytokinesis def: "A cellular process phenotype in which cytokinesis is abnormal." [PomBase:mah] synonym: "abnormal cell cycle cytokinesis" EXACT [PomBase:mah] synonym: "cytokinesis defects" EXACT [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process intersection_of: PATO:0000001 intersection_of: inheres_in GO:0033205 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000033 name: abnormal contractile ring localization def: "A cellular process phenotype in which contractile ring localization is abnormal." [PomBase:mah] synonym: "abnormal contractile ring localization involved in cell cycle cytokinesis" EXACT [PomBase:mah] synonym: "cytokinesis defects, misplaced contractile ring" EXACT [PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis is_a: FYPO:0000138 ! localization phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0032187 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000034 name: abnormal endocytosis def: "A cellular process phenotype in which endocytosis is abnormal." [PomBase:mah] synonym: "endocytosis defects" EXACT [PomBase:mah] is_a: FYPO:0000213 ! abnormal vesicle-mediated transport intersection_of: PATO:0000001 intersection_of: inheres_in GO:0006897 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000035 name: growth auxotrophic for arginine def: "Auxotrophy in which arginine is required for cell growth." [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy intersection_of: PATO:0000422 intersection_of: towards CHEBI:16467 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000036 name: growth auxotrophic for asparagine def: "Auxotrophy in which asparagine is required for cell growth." [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy intersection_of: PATO:0000422 intersection_of: towards CHEBI:17196 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000037 name: growth auxotrophic for cysteine def: "Auxotrophy in which cysteine is required for cell growth." [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy intersection_of: PATO:0000422 intersection_of: towards CHEBI:17561 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000038 name: growth auxotrophic for ethanolamine def: "Auxotrophy in which ethanolamine is required for cell growth." [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy intersection_of: PATO:0000422 intersection_of: towards CHEBI:16000 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000039 name: growth auxotrophic for lysine def: "Auxotrophy in which lysine is required for cell growth." [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy intersection_of: PATO:0000422 intersection_of: towards CHEBI:18019 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000040 name: growth auxotrophic for methionine def: "Auxotrophy in which methionine is required for cell growth." [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy intersection_of: PATO:0000422 intersection_of: towards CHEBI:16643 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000041 name: growth auxotrophic for phenylalanine def: "Auxotrophy in which phenylalanine is required for cell growth." [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy intersection_of: PATO:0000422 intersection_of: towards CHEBI:17295 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000042 name: growth auxotrophic for sulfite def: "Auxotrophy in which sulfite is required for cell growth." [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy intersection_of: qualifier PATO:0000422 intersection_of: towards CHEBI:17359 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000043 name: abnormal glucan synthesis def: "A cellular process phenotype in which glucan biosynthesis is abnormal." [PomBase:mah] synonym: "abnormal glucan biosynthetic process" EXACT [PomBase:mah] synonym: "glucan synthesis defective" EXACT [PomBase:mah] is_a: FYPO:0000140 ! cellular metabolism phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0009250 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000044 name: abnormal glucose repression alt_id: FYPO:0000210 def: "A cellular process phenotype in which negative regulation of transcription by glucose is abnormal." [PomBase:mah] synonym: "abnormal negative regulation of transcription by glucose" EXACT [PomBase:mah] synonym: "glucose repression defects" EXACT [PomBase:mah] is_a: FYPO:0000298 ! cellular response phenotype is_a: FYPO:0000624 ! abnormal negative regulation of transcription intersection_of: PATO:0000001 intersection_of: inheres_in GO:0045014 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000045 name: abnormal cell growth def: "A cellular process phenotype in which cell growth is abnormal." [PomBase:mah] synonym: "growth defect" EXACT [PomBase:mah] is_a: FYPO:0000139 ! cell growth phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0016049 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000046 name: slow cell growth def: "A cellular process phenotype in which cell growth is slower than normal." [PomBase:mah] synonym: "decreased cell growth rate" EXACT [PomBase:mah] synonym: "growth defect, slow growth" EXACT [PomBase:mah] is_a: FYPO:0000045 ! abnormal cell growth intersection_of: PATO:0000911 intersection_of: inheres_in GO:0016049 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000047 name: normal cell growth def: "A cellular process phenotype in which cells grow at a normal rate." [PomBase:mah] synonym: "growth normal" EXACT [PomBase:mah] is_a: FYPO:0000124 ! viable is_a: FYPO:0000139 ! cell growth phenotype is_a: FYPO:0000257 ! normal phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0016049 intersection_of: qualifier PATO:0000461 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000048 name: invasive growth abolished alt_id: FYPO:0000465 def: "A cellular process phenotype in which invasive growth is abolished." [PomBase:mah] comment: This term was made obsolete because it is not required to describe fission yeast. synonym: "absent invasive growth" EXACT [PomBase:mah] synonym: "invasive growth: absent" EXACT [SGD:phenotype_annotation] is_obsolete: true consider: FYPO:0000551 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000049 name: inviable def: "A viability phenotype in which cells are unable to survive under normal conditions." [PomBase:mah] is_a: FYPO:0000004 ! viability intersection_of: PATO:0000718 intersection_of: inheres_in CL:0000000 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000050 name: abnormal kinetochore structure def: "A cellular structure phenotype in which the structure of the kinetochore is abnormal." [PomBase:mah] synonym: "kinetochore defects" EXACT [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular structure intersection_of: PATO:0000001 intersection_of: inheres_in GO:0000776 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000051 name: abnormal meiosis def: "A cellular process phenotype in which meiosis is abnormal." [PomBase:mah] synonym: "meiosis defects" EXACT [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process intersection_of: PATO:0000001 intersection_of: inheres_in GO:0007126 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000052 name: abnormal meiotic cell cycle progression def: "A cellular process phenotype in which a cell does not proceed normally through a meiotic cell cycle." [PomBase:mah] synonym: "meiotic cell cycle defects" EXACT [PomBase:mah] is_a: FYPO:0000011 ! abnormal cell cycle progression intersection_of: PATO:0000001 intersection_of: inheres_in GO:0051321 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000054 name: abnormal microtubule organization alt_id: FYPO:0000053 def: "A phenotype that affects the organization of the microtubule cytoskeleton." [PomBase:mah] synonym: "abnormal microtubule cytoskeleton organization" EXACT [PomBase:mah] synonym: "microtubule cytoskeleton defects" EXACT [PomBase:mah] synonym: "microtubule organization defects" EXACT [PomBase:mah] is_a: FYPO:0000297 ! microtubule cytoskeleton organization phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0000226 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000055 name: long microtubules def: "A microtubule organization phenotype in which cells form microtubules that are longer than normal." [PomBase:mah] synonym: "microtubule organization defects, long microtubules" EXACT [PomBase:mah] is_a: FYPO:0000054 ! abnormal microtubule organization intersection_of: PATO:0000573 intersection_of: inheres_in GO:0005874 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000056 name: mitochondria fused def: "A cellular structure phenotype in which mitochondria have fused into fewer and larger structures than normal." [PomBase:mah] is_a: FYPO:0000359 ! abnormal mitochondrial morphology intersection_of: PATO:0000642 intersection_of: inheres_in GO:0005739 intersection_of: towards GO:0005739 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000057 name: mitochondrial nucleoid enlarged def: "A cellular structure phenotype in which the mitochondrial nucleoid is larger than normal." [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular structure intersection_of: PATO:0000586 intersection_of: inheres_in GO:0042645 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000058 name: mitochondrial nucleoid reduced number def: "A cellular structure phenotype in which a cell contains fewer mitochondrial nucleoids than normal." [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular structure intersection_of: PATO:0001997 intersection_of: inheres_in GO:0042645 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000059 name: abnormal mitotic cell cycle progression def: "A cellular process phenotype in which a cell does not proceed normally through a mitotic cell cycle." [PomBase:mah] synonym: "mitotic cell cycle defects" EXACT [PomBase:mah] synonym: "mitotic cell cycle: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000011 ! abnormal cell cycle progression intersection_of: PATO:0000001 intersection_of: inheres_in GO:0000278 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000060 name: mononucleate def: "A cellular structure phenotype in which a cell contains a single nucleus." [PomBase:mah] is_a: FYPO:0000136 ! cellular structure phenotype intersection_of: PATO:0001407 intersection_of: inheres_in CL:0000000 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000061 name: multinucleate def: "A cellular structure phenotype in which a cell contains more than one nucleus." [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular structure intersection_of: PATO:0001908 intersection_of: inheres_in CL:0000000 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000062 name: abnormal nuclear morphology alt_id: FYPO:0000259 def: "A cellular structure phenotype in which the morphology of the nucleus is abnormal." [PomBase:mah] synonym: "nuclear morphology defects" EXACT [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular structure intersection_of: PATO:0000051 intersection_of: inheres_in GO:0005634 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000063 name: abnormal DNA recombination def: "A cellular process phenotype in which DNA recombination is abnormal." [PomBase:mah] synonym: "recombination defects" EXACT [PomBase:mah] is_a: FYPO:0000293 ! DNA metabolism phenotype intersection_of: inheres_in GO:0006310 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000064 name: resistance to 2-deoxyglucose def: "An increased chemical resistance phenotype in which cells grow in the presence of a higher concentration of 2-deoxyglucose than normal." [PomBase:mah] synonym: "resistance to 2-DOG" EXACT [PomBase:mah] synonym: "resistant to 2-deoxy-D-glucose" EXACT [CHEBI:15866, PomBase:mah] synonym: "resistant to 2-DOG" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical intersection_of: PATO:0001552 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:15866 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000065 name: resistance to 5-azacytidine def: "An increased chemical resistance phenotype in which cells grow in the presence of a higher concentration of 5-azacytidine than normal." [PomBase:mah] synonym: "resistant to 5-azacytidine" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical intersection_of: PATO:0001552 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:2038 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000066 name: resistance to L-azetidine-2-carboxylic acid def: "An increased chemical resistance phenotype in which cells grow in the presence of a higher concentration of L-azetidine-2-carboxylic acid than normal." [PomBase:mah] synonym: "resistance to (S)-azetidine-2-carboxylic acid" EXACT [CHEBI:6198, PomBase:mah] synonym: "resistance to AZC" BROAD [PomBase:mah] synonym: "resistant to L-azetidine-2-carboxylic acid" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical intersection_of: PATO:0001552 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:6198 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000067 name: resistance to brefeldin A def: "An increased chemical resistance phenotype in which cells grow in the presence of a higher concentration of brefeldin A than normal." [PomBase:mah] synonym: "resistance to BFA" EXACT [PomBase:mah] synonym: "resistant to Brefeldin A" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical intersection_of: PATO:0001552 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:48080 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000068 name: resistance to K-252a def: "An increased chemical resistance phenotype in which cells grow in the presence of a higher concentration of K-252a than normal." [PomBase:mah] synonym: "resistant to K-252a" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical intersection_of: PATO:0001552 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:135352 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000069 name: resistance to thiabendazole def: "An increased chemical resistance phenotype in which cells grow in the presence of a higher concentration of thiabendazole than normal." [PomBase:mah] synonym: "resistance to TBZ" EXACT [PomBase:mah] synonym: "resistance to thiabendazole" EXACT [PomBase:mah] synonym: "resistant to TBZ" EXACT [CHEBI:45979, PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical intersection_of: PATO:0001552 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:45979 [Term] id: FYPO:0000070 name: resistance to amphotericin B def: "An increased chemical resistance phenotype in which cells grow in the presence of a higher concentration of amphotericin B than normal." [PomBase:mah] synonym: "resistant to amphotericin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical intersection_of: PATO:0001552 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:2682 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000071 name: resistance to aureobasidin A def: "An increased chemical resistance phenotype in which cells grow in the presence of a higher concentration of aureobasidin A than normal." [PomBase:mah] synonym: "resistance to AbA" EXACT [PMID:9472078] synonym: "resistant to aureobasidin A" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical intersection_of: PATO:0001552 intersection_of: inheres_in GO:0016049 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000072 name: resistance to benomyl def: "An increased chemical resistance phenotype in which cells grow in the presence of a higher concentration of benomyl than normal." [PomBase:mah] synonym: "resistant to benomyl" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical intersection_of: PATO:0001552 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:3015 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000073 name: resistance to caffeine def: "An increased chemical resistance phenotype in which cells grow in the presence of a higher concentration of caffeine than normal." [PomBase:mah] synonym: "resistant to caffeine" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical intersection_of: PATO:0001552 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:27732 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000074 name: resistance to drug def: "An increased chemical resistance phenotype in which cells grow in the presence of a higher concentration of a drug than normal." [PomBase:mah] synonym: "drug resistance" EXACT [PomBase:mah] synonym: "drug resistant" EXACT [PomBase:mah] synonym: "resistant to drugs" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical intersection_of: PATO:0001552 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:23888 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000075 name: resistance to lovastatin def: "An increased chemical resistance phenotype in which cells grow in the presence of a higher concentration of lovastatin than normal." [PomBase:mah] synonym: "resistant to lovastatin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical intersection_of: PATO:0001552 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:40303 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000076 name: resistance to nystatin def: "An increased chemical resistance phenotype in which cells grow in the presence of a higher concentration of nystatin than normal." [PomBase:mah] synonym: "resistant to nystatin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical intersection_of: PATO:0001552 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:7660 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000077 name: resistance to rapamycin def: "An increased chemical resistance phenotype in which cells grow in the presence of a higher concentration of rapamycin than normal." [PomBase:mah] synonym: "resistant to rapamycin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical intersection_of: PATO:0001552 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:9168 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000078 name: abnormal cellular respiration def: "A cellular process phenotype in which cellular respiration is abnormal." [PomBase:mah] synonym: "abnormal respiration" BROAD [PomBase:mah] synonym: "abnormal respiratory metabolism" EXACT [PomBase:mah] synonym: "respiratory metabolism: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000140 ! cellular metabolism phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0045333 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000079 name: sensitive to caspofungin def: "A phenotype in which cells show increased sensitivity to caspofungin." [PomBase:mah] synonym: "sensitive to glucan synthase inhibitor" BROAD [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:474180 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000080 name: sensitive to cold def: "A cell phenotype in which cells show increased sensitivity to cold; cells fail to grow or grow more slowly than normal at low temperatures." [PomBase:mah] is_a: FYPO:0000304 ! sensitive to stress intersection_of: PATO:0001551 intersection_of: inheres_in GO:0070417 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000081 name: sensitive to high osmolarity def: "A cell phenotype in which cells show increased sensitivity to conditions of high osmolarity." [PomBase:mah] synonym: "sensitive to hyperosmotic conditions" EXACT [PomBase:mah] is_a: FYPO:0000270 ! sensitive to osmotic stress intersection_of: PATO:0001551 intersection_of: inheres_in GO:0071474 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000082 name: sensitive to high temperature def: "A cell phenotype in which cells show increased sensitivity to heat; cells fail to grow or grow more slowly than normal at high temperatures." [PomBase:mah] synonym: "heat sensitive" EXACT [PomBase:mah] synonym: "sensitive to heat" EXACT [PomBase:mah] synonym: "temperature sensitive" RELATED [PomBase:mah] is_a: FYPO:0000212 ! abnormal cellular response to heat is_a: FYPO:0000304 ! sensitive to stress intersection_of: PATO:0001551 intersection_of: inheres_in GO:0034605 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000083 name: sensitive to enfumafungin def: "A phenotype in which cells show increased sensitivity to enfumafungin." [PomBase:mah] synonym: "sensitive to glucan synthase inhibitor" BROAD [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:61749 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000084 name: sensitive to 6-azauracil def: "A phenotype in which cells show increased sensitivity to 6-azauracil." [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:53745 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000085 name: sensitive to camptothecin def: "A phenotype in which cells show increased sensitivity to camptothecin." [PomBase:mah] synonym: "sensitive to CPT" EXACT [CHEBI:27656, PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:27656 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000086 name: sensitive to tacrolimus def: "A phenotype in which cells show increased sensitivity to tacrolimus." [PomBase:mah] comment: was mistyped FK605 synonym: "sensitive to FK506" EXACT [CHEBI:61057, PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:61057 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000087 name: sensitive to hydrogen peroxide def: "A phenotype in which cells show increased sensitivity to hydrogen peroxide." [PomBase:mah] synonym: "sensitive to H2O2" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:16240 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000088 name: sensitive to hydroxyurea def: "A phenotype in which cells show increased sensitivity to hydroxyurea." [PomBase:mah] synonym: "sensitive to HU" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:44423 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000089 name: sensitive to methyl methanesulfonate def: "A phenotype in which cells show increased sensitivity to methyl methanesulfonate." [PomBase:mah] synonym: "sensitive to MMS" EXACT [CHEBI:25255, PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:25255 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000090 name: sensitive to N-ethylmaleimide def: "A phenotype in which cells show increased sensitivity to N-ethylmaleimide." [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:44485 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000091 name: sensitive to thiabendazole def: "A phenotype in which cells show increased sensitivity to thiabendazole." [PomBase:mah] synonym: "sensitive to TBZ" EXACT [CHEBI:45979, PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:45979 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000092 name: sensitive to amiodarone def: "A phenotype in which cells show increased sensitivity to amiodarone." [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:2663 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000093 name: sensitive to arsenic def: "A phenotype in which cells show increased sensitivity to arsenic." [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:22632 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000094 name: sensitive to benomyl def: "A phenotype in which cells show increased sensitivity to benomyl." [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:3015 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000095 name: sensitive to bleomycin def: "A phenotype in which cells show increased sensitivity to bleomycin." [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:22907 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000096 name: sensitive to cadmium def: "A phenotype in which cells show increased sensitivity to cadmium." [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:22978 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000097 name: sensitive to caffeine def: "A phenotype in which cells show increased sensitivity to caffeine." [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:27732 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000098 name: sensitive to calcium def: "A phenotype in which cells show increased sensitivity to calcium." [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:29108 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000099 name: sensitive to canavanine def: "A phenotype in which cells show increased sensitivity to canavanine." [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:609827 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000100 name: sensitive to chloramphenicol def: "A phenotype in which cells show increased sensitivity to chloramphenicol." [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:17698 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000101 name: sensitive to chlorpropham def: "A phenotype in which cells show increased sensitivity to chlorpropham." [PomBase:mah] synonym: "sensitive to isopropyl N-3-chlorophenyl carbamate" EXACT [PomBase:mah] synonym: "sensitive to spindle poison" BROAD [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000102 name: sensitive to cisplatin def: "A phenotype in which cells show increased sensitivity to cisplatin." [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:27899 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000103 name: sensitive to copper ions def: "A phenotype in which cells show increased sensitivity to copper ions." [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:23378 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000104 name: sensitive to cycloheximide def: "A phenotype in which cells show increased sensitivity to cycloheximide." [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:27641 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000105 name: sensitive to cyclosporin A def: "A phenotype in which cells show increased sensitivity to cyclosporin A." [PomBase:mah] synonym: "sensitive to cyclosporine" EXACT [CHEBI:4031, PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:4031 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000106 name: sensitive to hygromycin B def: "A phenotype in which cells show increased sensitivity to hygromycin B." [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:16976 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000107 name: sensitive to latrunculin A def: "A phenotype in which cells show increased sensitivity to latrunculin A." [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:43626 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000108 name: sensitive to menadione def: "A phenotype in which cells show increased sensitivity to menadione." [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000109 name: sensitive to papulacandin B def: "A phenotype in which cells show increased sensitivity to papulacandin B." [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:569624 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000110 name: sensitive to pravastatin def: "A phenotype in which cells show increased sensitivity to pravastatin." [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000111 name: sensitive to rapamycin def: "A phenotype in which cells show increased sensitivity to rapamycin." [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:9168 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000112 name: sensitive to sorbitol def: "A phenotype in which cells show increased sensitivity to sorbitol." [PomBase:mah] synonym: "sensitive to glucitol" EXACT [CHEBI:30911, PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:30911 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000113 name: sensitive to staurosporine def: "A phenotype in which cells show increased sensitivity to staurosporine." [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:15738 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000114 name: cellular process phenotype def: "A phenotype that affects a cellular process." [PomBase:mah] is_a: FYPO:0000002 ! cell phenotype is_a: FYPO:0000300 ! biological process phenotype intersection_of: FYPO:0000001 ! phenotype intersection_of: inheres_in GO:0009987 created_by: midori creation_date: 2011-04-12T12:00:38Z [Term] id: FYPO:0000115 name: sensitive to valproic acid def: "A phenotype in which cells show increased sensitivity to valproic acid." [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:39867 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000116 name: sensitive to zinc def: "A phenotype in which cells show increased sensitivity to zinc." [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:27365 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000117 name: abnormal septation alt_id: FYPO:0000170 def: "A cellular process phenotype in which septation is abnormal." [PomBase:mah] synonym: "abnormal barrier septum formation involved in cell cycle cytokinesis" EXACT [PomBase:mah] synonym: "septation defects" EXACT [PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis is_a: FYPO:0000336 ! abnormal cellular component assembly intersection_of: PATO:0000001 intersection_of: inheres_in GO:0071937 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000118 name: multiseptate def: "A septation phenotype characterized by the presence of more than one septum in a cell." [PomBase:mah] synonym: "septation defects, multiple septa" EXACT [PomBase:mah] is_a: FYPO:0000117 ! abnormal septation is_a: FYPO:0000287 ! abnormal subcellular structure intersection_of: PATO:0000470 intersection_of: inheres_in GO:0000935 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000119 name: abnormal spindle assembly alt_id: FYPO:0000285 def: "A cellular process phenotype in which spindle assembly is abnormal." [PomBase:mah] is_a: FYPO:0000054 ! abnormal microtubule organization is_a: FYPO:0000336 ! abnormal cellular component assembly intersection_of: PATO:0000001 intersection_of: inheres_in GO:0051225 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000120 name: abnormal spindle alt_id: FYPO:0000367 def: "A cellular structure phenotype in which the structure of the mitotic or meiotic spindle is abnormal." [PomBase:mah] synonym: "abnormal spindle morphology" EXACT [] synonym: "spindle defects" EXACT [PomBase:mah] synonym: "spindle morphology: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000287 ! abnormal subcellular structure intersection_of: PATO:0000001 intersection_of: inheres_in GO:0005819 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000121 name: abnormal sporulation def: "A cellular process phenotype in which ascospore formation is abnormal." [PomBase:mah] synonym: "abnormal ascospore formation" EXACT [PomBase:mah] synonym: "sporulation defects" EXACT [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process intersection_of: PATO:0000001 intersection_of: inheres_in GO:0030437 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000122 name: abnormal telomere maintenance def: "A cellular process phenotype in which telomere maintenance is abnormal." [PomBase:mah] synonym: "telomere maintenance defects" EXACT [PomBase:mah] is_a: FYPO:0000145 ! regulation phenotype is_a: FYPO:0000293 ! DNA metabolism phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0000723 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000123 name: large vacuoles def: "A cellular structure phenotype in which vacuoles are larger than normal." [PomBase:mah] synonym: "vacuole organization defects, large vacuoles" EXACT [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular structure intersection_of: PATO:0000586 intersection_of: inheres_in GO:0000324 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000124 name: viable def: "A viability phenotype in which cells are able to survive under normal conditions." [PomBase:mah] is_a: FYPO:0000004 ! viability intersection_of: PATO:0000719 intersection_of: inheres_in CL:0000000 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000125 name: resistance to amiloride def: "An increased chemical resistance phenotype in which cells grow in the presence of a higher concentration of amiloride than normal." [PomBase:mah] synonym: "resistant to amiloride" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical intersection_of: PATO:0001552 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:2639 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000126 name: increased resistance to chemical def: "A phenotype in which a cell shows increased resistance to a chemical stimulus. Resistance to a chemical is usually measured by determining the maximum concentration of the chemical at which cells grow and divide." [PomBase:mah] is_a: FYPO:0000002 ! cell phenotype intersection_of: PATO:0001552 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:24431 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000127 name: increased sensitivity to chemical def: "A phenotype in which a cell shows decreased resistance to a chemical stimulus. Resistance to a chemical is measured by determining the maximum concentration of the chemical at which cells grow and divide." [PomBase:mah] is_a: FYPO:0000002 ! cell phenotype intersection_of: PATO:0001551 intersection_of: inheres_in GO:0016049 intersection_of: towards CHEBI:24431 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000128 name: auxotrophy def: "A phenotype characterized by a cell's inability to synthesize a particular organic compound required for its growth." [PATO:0000422, PomBase:mah] is_a: FYPO:0000139 ! cell growth phenotype is_a: FYPO:0000140 ! cellular metabolism phenotype intersection_of: inheres_in CL:0000000 intersection_of: qualifier PATO:0000422 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000129 name: spherical cells def: "A cell morphology phenotype in which cells are formed in the shape of a sphere." [PomBase:mah] is_a: FYPO:0000021 ! spheroid cells intersection_of: PATO:0001499 intersection_of: inheres_in CL:0000000 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000130 name: short spindles def: "A spindle phenotype in which the spindle is shorter than normal." [PomBase:mah] synonym: "spindle defects, short spindles" EXACT [PomBase:mah] is_a: FYPO:0000120 ! abnormal spindle intersection_of: PATO:0000574 intersection_of: inheres_in GO:0005819 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000131 name: abnormal mitotic spindle elongation def: "A spindle phenotype in which the process of mitotic spindle elongation is abnormal." [PomBase:mah] synonym: "spindle elongation defects" EXACT [PomBase:mah] is_a: FYPO:0000337 ! abnormal mitosis intersection_of: PATO:0000001 intersection_of: inheres_in GO:0000022 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000132 name: abnormal septum disassembly def: "A cellular process phenotype characterized by abnormal primary cell septum disassembly; may result in the formation of chains of attached cells." [PomBase:mah] synonym: "chained cells" RELATED [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process intersection_of: PATO:0000001 intersection_of: inheres_in GO:0005819 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000133 name: elongated multinucleate cells def: "A cell phenotype in which cells contain more than one nucleus apiece and are elongated." [PomBase:mah] is_a: FYPO:0000017 ! elongated cells is_a: FYPO:0000061 ! multinucleate intersection_of: has_part FYPO:0000017 ! elongated cells intersection_of: has_part FYPO:0000061 ! multinucleate created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000134 name: branched, elongated, multiseptate cells def: "A cell morphology phenotype in which cells form branches near the septum, are elongated, and have more than one septum per cell." [PomBase:mah] is_a: FYPO:0000015 ! branched cells is_a: FYPO:0000223 ! elongated, multiseptate cells intersection_of: has_part FYPO:0000015 ! branched cells intersection_of: has_part FYPO:0000017 ! elongated cells intersection_of: has_part FYPO:0000118 ! multiseptate created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000135 name: abnormal plasma membrane sterol distribution def: "A localization phenotype in which the distribution of sterols in the plasma membrane is abnormal." [PomBase:mah] synonym: "abnormal regulation of plasma membrane sterol distribution" EXACT [PomBase:mah] synonym: "localization defects, sterol distribution defects" EXACT [PomBase:mah] is_a: FYPO:0000138 ! localization phenotype is_a: FYPO:0000145 ! regulation phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0097036 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000136 name: cellular structure phenotype def: "A phenotype that affects the structure of a cell or a cellular component." [PomBase:mah] is_a: FYPO:0000002 ! cell phenotype intersection_of: FYPO:0000002 ! cell phenotype intersection_of: inheres_in GO:0005575 created_by: midori creation_date: 2011-04-12T12:01:21Z [Term] id: FYPO:0000137 name: cell cycle checkpoint phenotype def: "A cell phenotype that affects any cell cycle checkpoint." [PomBase:mah] is_a: FYPO:0000145 ! regulation phenotype is_a: FYPO:0000631 ! cell cycle phenotype intersection_of: FYPO:0000002 ! cell phenotype intersection_of: inheres_in GO:0000075 created_by: midori creation_date: 2011-04-12T12:55:38Z [Term] id: FYPO:0000138 name: localization phenotype def: "A cell phenotype that affects the localization of a structure or substance in a cell." [PomBase:mah] is_a: FYPO:0000114 ! cellular process phenotype intersection_of: FYPO:0000002 ! cell phenotype intersection_of: inheres_in GO:0051641 created_by: midori creation_date: 2011-04-12T02:16:04Z [Term] id: FYPO:0000139 name: cell growth phenotype def: "A cell phenotype that affects the rate or extent of cell growth." [PomBase:mah] is_a: FYPO:0000114 ! cellular process phenotype intersection_of: FYPO:0000002 ! cell phenotype intersection_of: inheres_in GO:0016049 created_by: midori creation_date: 2011-04-12T02:22:51Z [Term] id: FYPO:0000140 name: cellular metabolism phenotype def: "A cellular process phenotype that affects metabolism in the cell." [PomBase:mah] is_a: FYPO:0000114 ! cellular process phenotype intersection_of: FYPO:0000002 ! cell phenotype intersection_of: inheres_in GO:0044237 created_by: midori creation_date: 2011-04-12T02:23:26Z [Term] id: FYPO:0000141 name: abnormal mitotic sister chromatid segregation def: "A cellular process phenotype in which mitotic sister chromatid segregation is abnormal." [PomBase:mah] synonym: "abnormal mitotic chromosome segregation" EXACT [PomBase:mah] synonym: "chromosome segregation defects, mitotic" EXACT [PomBase:mah] is_a: FYPO:0000029 ! abnormal chromosome segregation intersection_of: PATO:0000001 intersection_of: inheres_in GO:0000070 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-12T05:41:15Z [Term] id: FYPO:0000142 name: gene expression phenotype def: "A cellular process phenotype that affects gene expression." [PomBase:mah] is_a: FYPO:0000114 ! cellular process phenotype intersection_of: FYPO:0000002 ! cell phenotype intersection_of: inheres_in GO:0010467 created_by: midori creation_date: 2011-04-12T05:46:51Z [Term] id: FYPO:0000143 name: transcription regulation phenotype def: "A gene expression phenotype that affects the regulation of DNA-dependent transcription." [PomBase:mah] synonym: "gene-specific transcription regulation phenotype" RELATED [GO:0006355, PomBase:mah] synonym: "transcriptional control phenotype" BROAD [GO:0006355, PomBase:mah] is_a: FYPO:0000288 ! gene expression regulation phenotype intersection_of: FYPO:0000002 ! cell phenotype intersection_of: inheres_in GO:0006355 created_by: midori creation_date: 2011-04-12T05:47:38Z [Term] id: FYPO:0000144 name: abnormal chromatin silencing def: "A transcription regulation phenotype in which chromatin silencing is abnormal." [PomBase:mah] is_a: FYPO:0000574 ! abnormal gene silencing is_a: FYPO:0000624 ! abnormal negative regulation of transcription intersection_of: PATO:0000001 intersection_of: inheres_in GO:0006342 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-12T05:48:37Z [Term] id: FYPO:0000145 name: regulation phenotype def: "A cellular process phenotype that affects the regulation of a molecular function, biological process, or biological quality." [PomBase:mah] is_a: FYPO:0000114 ! cellular process phenotype intersection_of: FYPO:0000002 ! cell phenotype intersection_of: inheres_in GO:0065007 created_by: midori creation_date: 2011-04-12T06:00:44Z [Term] id: FYPO:0000146 name: abnormal chromatin silencing at centromere def: "A transcription regulation phenotype in which chromatin silencing at centromeric regions is abnormal." [PomBase:mah] is_a: FYPO:0000144 ! abnormal chromatin silencing intersection_of: PATO:0000001 intersection_of: inheres_in GO:0030702 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000147 name: abnormal activation of bipolar cell growth def: "A regulation phenotype in which activation of bipolar cell growth is abnormal; results in abnormal new end take-off." [PomBase:mah] synonym: "abnormal NETO" EXACT [PomBase:mah] synonym: "abnormal new end take off" EXACT [PomBase:mah] is_a: FYPO:0000191 ! abnormal regulation of establishment or maintenance of cell polarity intersection_of: PATO:0000001 intersection_of: inheres_in GO:0051519 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000148 name: abnormal regulation of mitotic cell cycle def: "A regulation phenotype in which regulation of the mitotic cell cycle is abnormal." [PomBase:mah] is_a: FYPO:0000011 ! abnormal cell cycle progression is_a: FYPO:0000145 ! regulation phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0007346 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000149 name: transport phenotype def: "A cell process phenotype that affects a transport process." [PomBase:mah] is_a: FYPO:0000138 ! localization phenotype intersection_of: FYPO:0000002 ! cell phenotype intersection_of: inheres_in GO:0006810 created_by: midori creation_date: 2011-04-14T05:43:20Z [Term] id: FYPO:0000150 name: abnormal colony morphology def: "A cell population phenotype in which the morphology of a colony growing on a solid surface is abnormal." [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype created_by: midori creation_date: 2011-04-19T02:50:53Z [Term] id: FYPO:0000151 name: abnormal meiotic chromosome segregation def: "A cellular process phenotype in which meiotic chromosome segregation is abnormal." [PomBase:mah] is_a: FYPO:0000029 ! abnormal chromosome segregation is_a: FYPO:0000051 ! abnormal meiosis intersection_of: PATO:0000001 intersection_of: inheres_in GO:0045132 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000152 name: abnormal cellular response to nitrogen starvation def: "A stress response phenotype in which the response to nitrogen starvation is abnormal." [PomBase:mah] is_a: FYPO:0000162 ! abnormal cellular response to stress intersection_of: PATO:0000001 intersection_of: inheres_in GO:0006995 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000153 name: clumped cells def: "A colony morphology phenotype in which cells form clumps due to incomplete hydrolysis of septum edging material; cells remain attached via remnants of the septum edging." [PMID:15194814, PomBase:mah] is_a: FYPO:0000150 ! abnormal colony morphology created_by: midori creation_date: 2011-04-19T02:50:53Z [Term] id: FYPO:0000154 name: abnormal negative regulation of G0 to G1 transition def: "A regulation phenotype in which negative regulation of the G0 to G1 transition is abnormal." [PomBase:mah] synonym: "abnormal maintenance of cell cycle quiescence" EXACT [PomBase:mah] synonym: "abnormal maintenance of cell quiescence" EXACT [PomBase:mah] synonym: "abnormal maintenance of G0 arrest" EXACT [PomBase:mah] synonym: "abnormal maintenance of G0 phase" EXACT [PomBase:mah] is_a: FYPO:0000145 ! regulation phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0070317 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000155 name: flocculating cells alt_id: FYPO:0000462 def: "A cell population phenotype that reflects increased occurrence of flocculation. Flocculation is the non-sexual aggregation of single cells." [GO:0000128, PomBase:mah] synonym: "flocculation: increased" EXACT [SGD:phenotype_annotation] synonym: "increased flocculation" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0000300 ! biological process phenotype intersection_of: PATO:0002051 intersection_of: inheres_in GO:0000128 created_by: midori creation_date: 2011-04-19T02:50:53Z [Term] id: FYPO:0000156 name: abnormal chromatin silencing at silent mating-type cassette def: "A transcription regulation phenotype in which chromatin silencing at the silent mating-type cassettes is abnormal." [PomBase:mah] is_a: FYPO:0000144 ! abnormal chromatin silencing intersection_of: PATO:0000001 intersection_of: inheres_in GO:0030466 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000157 name: abnormal response to DNA damage stimulus def: "A stress response phenotype in which the response to DNA damage is abnormal." [PomBase:mah] is_a: FYPO:0000162 ! abnormal cellular response to stress intersection_of: PATO:0000001 intersection_of: inheres_in GO:0006974 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000158 name: DNA content increased def: "A cell phenotype in which a cell contains more DNA than normal." [PomBase:mah] is_a: FYPO:0000002 ! cell phenotype intersection_of: PATO:0001162 intersection_of: inheres_in CL:0000000 intersection_of: towards CHEBI:16991 created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000159 name: abnormal chromosome condensation alt_id: FYPO:0000028 def: "A cellular process phenotype in which chromosome condensation is abnormal." [PomBase:mah] synonym: "chromosome condensation defects" EXACT [PomBase:mah] is_a: FYPO:0000293 ! DNA metabolism phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0030261 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-14T10:44:38Z [Term] id: FYPO:0000160 name: DNA fragmentation def: "A cell phenotype in which DNA is broken into small fragments." [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular structure intersection_of: PATO:0001444 intersection_of: inheres_in CHEBI:16991 created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000161 name: abnormal actomyosin contractile ring assembly def: "A cellular process phenotype in which contractile ring assembly is abnormal." [PomBase:mah] synonym: "abnormal contractile ring assembly" EXACT [PomBase:mah] synonym: "abnormal cytokinesis, actomyosin contractile ring assembly" EXACT [PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis is_a: FYPO:0000296 ! actin cytoskeleton organization phenotype is_a: FYPO:0000336 ! abnormal cellular component assembly intersection_of: PATO:0000001 intersection_of: inheres_in GO:0000915 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000162 name: abnormal cellular response to stress def: "A cellular response phenotype in which a cellular response to stress is abnormal." [PomBase:mah] is_a: FYPO:0000298 ! cellular response phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0033554 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000163 name: abnormal autophagy alt_id: FYPO:0000379 def: "A cellular process phenotype in which autophagy is abnormal." [PomBase:mah] synonym: "autophagy: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000140 ! cellular metabolism phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0006914 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000164 name: abnormal cytokinetic cell separation def: "A cellular process phenotype in which cytokinetic cell separation is abnormal." [PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis intersection_of: PATO:0000001 intersection_of: inheres_in GO:0000920 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000165 name: abnormal regulation of conjugation def: "A regulation phenotype in which regulation of conjugation is abnormal." [PomBase:mah] synonym: "abnormal regulation of conjugation with cellular fusion" EXACT [PomBase:mah] is_a: FYPO:0000145 ! regulation phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0031137 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000166 name: abnormal regulation of G2/M transition of mitotic cell cycle def: "A regulation phenotype in which negative regulation of the G2 to M transition of the mitotic cell cycle is abnormal." [PomBase:mah] is_a: FYPO:0000148 ! abnormal regulation of mitotic cell cycle intersection_of: PATO:0000001 intersection_of: inheres_in GO:0010389 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000167 name: increased DNA recombination at mitotic DNA replication fork barriers def: "A cellular process phenotype in which the frequency of DNA recombination at replication fork barriers is increased." [PomBase:mah] synonym: "DNA recombination defect, at mitotic DNA replication fork barriers, elevated" EXACT [PomBase:mah] is_a: FYPO:0000063 ! abnormal DNA recombination created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000168 name: abnormal mitotic cell cycle spindle assembly checkpoint def: "A cell cycle checkpoint phenotype that affects the spindle assembly checkpoint of a mitotic cell cycle." [PomBase:mah] is_a: FYPO:0000137 ! cell cycle checkpoint phenotype is_a: FYPO:0000200 ! abnormal regulation of mitotic metaphase/anaphase transition intersection_of: PATO:0000001 intersection_of: inheres_in GO:0007094 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000169 name: abnormal chromatin silencing at telomere def: "A transcription regulation phenotype in which chromatin silencing at telomeric regions is abnormal." [PomBase:mah] is_a: FYPO:0000144 ! abnormal chromatin silencing intersection_of: PATO:0000001 intersection_of: inheres_in GO:0006348 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000171 name: abnormal late endosome to vacuole transport def: "A transport phenotype in which late endosome to vacuole transport is abnormal." [PomBase:mah] is_a: FYPO:0000213 ! abnormal vesicle-mediated transport is_a: FYPO:0000597 ! abnormal vacuolar transport intersection_of: PATO:0000001 intersection_of: inheres_in GO:0045324 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000172 name: abnormal meiotic telomere clustering def: "A meiosis phenotype in which meiotic telomere clustering is abnormal." [PomBase:mah] is_a: FYPO:0000051 ! abnormal meiosis is_a: FYPO:0000138 ! localization phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0045141 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000173 name: abnormal mitotic cell cycle DNA replication checkpoint def: "A cell cycle checkpoint phenotype that affects the DNA replication checkpoint in a mitotic cell cycle." [PomBase:mah] is_a: FYPO:0000166 ! abnormal regulation of G2/M transition of mitotic cell cycle is_a: FYPO:0000643 ! abnormal DNA integrity checkpoint intersection_of: PATO:0000001 intersection_of: inheres_in GO:0033314 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000174 name: abnormal cell wall biogenesis def: "A cellular process phenotype in which cell wall biogenesis is abnormal." [PomBase:mah] synonym: "abnormal fungal-type cell wall biogenesis" EXACT [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process intersection_of: PATO:0000001 intersection_of: inheres_in GO:0009272 intersection_of: qualifier PATO:0000460 relationship: results_in_formation_of FYPO:0000027 ! abnormal cell wall created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000175 name: abnormal ascospore wall assembly def: "A sporulation phenotype in which ascospore wall assembly is abnormal." [PomBase:mah] synonym: "abnormal spore wall formation" RELATED [PomBase:mah] synonym: "spore wall formation: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000336 ! abnormal cellular component assembly intersection_of: PATO:0000001 intersection_of: inheres_in GO:0030476 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000176 name: abnormal DNA replication initiation def: "A cellular process phenotype in which the initiation of DNA replication is abnormal." [PomBase:mah] synonym: "abnormal DNA-dependent DNA replication initiation" EXACT [PomBase:mah] is_a: FYPO:0000217 ! abnormal DNA replication intersection_of: PATO:0000001 intersection_of: inheres_in GO:0006270 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000177 name: abnormal mitotic spindle assembly def: "A cellular process phenotype in which assembly of the mitotic spindle is abnormal." [PomBase:mah] synonym: "abnormal spindle assembly involved in mitosis" EXACT [PomBase:mah] is_a: FYPO:0000119 ! abnormal spindle assembly is_a: FYPO:0000337 ! abnormal mitosis intersection_of: PATO:0000001 intersection_of: inheres_in GO:0090307 intersection_of: qualifier PATO:0000460 relationship: results_in_formation_of FYPO:0000338 ! abnormal mitotic spindle created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000178 name: abnormal regulation of cytokinesis def: "A regulation phenotype in which regulation of cytokinesis is abnormal." [PomBase:mah] synonym: "abnormal regulation of cell cycle cytokinesis" EXACT [PomBase:mah] is_a: FYPO:0000145 ! regulation phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0071775 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000179 name: abnormal protein targeting via the multivesicular body sorting pathway def: "A cellular process phenotype in which protein targeting to the vacuole via the multivesicular sorting pathway, leading to ubiquitin-dependent protein degradation, is abnormal." [PomBase:mah] synonym: "abnormal protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway" EXACT [PomBase:mah] is_a: FYPO:0000171 ! abnormal late endosome to vacuole transport is_a: FYPO:0000676 ! abnormal protein targeting to vacuole intersection_of: PATO:0000001 intersection_of: inheres_in GO:0043328 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000180 name: abnormal cellular response to oxidative stress def: "A stress response phenotype in which a cellular response to oxidative stress is abnormal." [PomBase:mah] is_a: FYPO:0000162 ! abnormal cellular response to stress intersection_of: PATO:0000001 intersection_of: inheres_in GO:0034599 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000181 name: crossover abolished def: "A DNA recombination phenotype in which reciprocal DNA recombination does not occur." [PomBase:mah] synonym: "DNA recombination defects, crossover, abolished" EXACT [PomBase:mah] is_a: FYPO:0000063 ! abnormal DNA recombination intersection_of: PATO:0001508 intersection_of: inheres_in GO:0035825 created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000182 name: abnormal cell wall organization def: "A cellular process phenotype in which cell wall organization is abnormal." [PomBase:mah] synonym: "abnormal fungal-type cell wall organization" EXACT [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process intersection_of: PATO:0000001 intersection_of: inheres_in GO:0031505 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000183 name: abnormal poly(A)+ mRNA export from nucleus def: "A transport phenotype in which the export of polyadenylated mRNA from the nucleus is abnormal." [PomBase:mah] is_a: FYPO:0000204 ! abnormal mRNA export from nucleus intersection_of: PATO:0000001 intersection_of: inheres_in GO:0016973 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000184 name: abnormal regulation of filamentous growth def: "A regulation phenotype in which regulation of filamentous growth is abnormal." [PomBase:mah] is_a: FYPO:0000145 ! regulation phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0010570 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000185 name: reduced gene conversion def: "A DNA recombination phenotype in which the occurrence of gene conversion is reduced." [PomBase:mah] synonym: "DNA recombination defects, gene conversion, reduced" EXACT [PomBase:mah] is_a: FYPO:0000063 ! abnormal DNA recombination intersection_of: PATO:0002052 intersection_of: inheres_in GO:0035822 creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000186 name: abnormal cell division def: "A cellular process phenotype in which cell division is abnormal." [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process intersection_of: PATO:0000001 intersection_of: inheres_in GO:0051301 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000187 name: abnormal chromatin silencing by small RNA def: "A transcription regulation phenotype in which chromatin silencing mediated by small RNA is abnormal." [PomBase:mah] is_a: FYPO:0000144 ! abnormal chromatin silencing intersection_of: PATO:0000001 intersection_of: inheres_in GO:0031048 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000188 name: abnormal DNA repair def: "A cellular process phenotype in which DNA repair is abnormal." [PomBase:mah] is_a: FYPO:0000157 ! abnormal response to DNA damage stimulus is_a: FYPO:0000293 ! DNA metabolism phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0006281 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000189 name: abnormal nuclear mRNA splicing, via spliceosome def: "A cellular process phenotype in which mRNA splicing via the spliceosome is abnormal." [PomBase:mah] is_a: FYPO:0000294 ! RNA metabolism phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0000398 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000190 name: abnormal actin cortical patch localization def: "A cellular process phenotype in which actin cortical patch localization is abnormal." [PomBase:mah] is_a: FYPO:0000138 ! localization phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0051666 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000191 name: abnormal regulation of establishment or maintenance of cell polarity def: "A regulation phenotype in which regulation of the establishment or maintenance of cell polarity is abnormal." [PomBase:mah] is_a: FYPO:0000145 ! regulation phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0032878 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000192 name: abnormal regulation of S phase of mitotic cell cycle def: "A regulation phenotype in which regulation of progression through S phase of the mitotic cell cycle is abnormal." [PomBase:mah] is_a: FYPO:0000148 ! abnormal regulation of mitotic cell cycle intersection_of: PATO:0000001 intersection_of: inheres_in GO:0007090 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000193 name: abnormal cellular response to osmotic stress def: "A stress response phenotype in which a cellular response to osmotic stress is abnormal." [PomBase:mah] is_a: FYPO:0000162 ! abnormal cellular response to stress intersection_of: PATO:0000001 intersection_of: inheres_in GO:0071470 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000194 name: abnormal cellular response to hydrogen peroxide def: "A stress response phenotype in which a cellular response to hydrogen peroxide is abnormal." [PomBase:mah] is_a: FYPO:0000180 ! abnormal cellular response to oxidative stress intersection_of: PATO:0000001 intersection_of: inheres_in GO:0070301 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000196 name: abnormal prospore formation def: "A sporulation phenotype in which prospore formation is abnormal." [PomBase:mah] synonym: "abnormal ascospore-type prospore formation" EXACT [PomBase:mah] is_a: FYPO:0000336 ! abnormal cellular component assembly intersection_of: PATO:0000001 intersection_of: inheres_in GO:0031321 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000197 name: abnormal dynein-driven meiotic oscillatory nuclear movement def: "A cellular process phenotype in which dynein-driven oscillatory nuclear movement during meiosis is abnormal." [PomBase:mah] is_a: FYPO:0000149 ! transport phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0030989 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000198 name: abnormal establishment or maintenance of actin cytoskeleton polarity def: "A cellular process phenotype in which the establishment or maintenance of actin cytoskeleton polarity is abnormal." [PomBase:mah] is_a: FYPO:0000026 ! abnormal cell polarity is_a: FYPO:0000296 ! actin cytoskeleton organization phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0030950 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000199 name: increased long tract gene conversion def: "A DNA recombination phenotype in which the occurrence of long tract gene conversion is increased." [PomBase:mah] synonym: "DNA recombination defects, long tract gene conversion, increased" EXACT [PomBase:mah] is_a: FYPO:0000063 ! abnormal DNA recombination intersection_of: PATO:0002051 intersection_of: inheres_in GO:0035824 created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000200 name: abnormal regulation of mitotic metaphase/anaphase transition def: "A regulation phenotype in which regulation of the mitotic metaphase to anaphase transition is abnormal." [PomBase:mah] is_a: FYPO:0000148 ! abnormal regulation of mitotic cell cycle intersection_of: PATO:0000001 intersection_of: inheres_in GO:0030071 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000201 name: abnormal histone deacetylation def: "A cellular process phenotype in which histone deacetylation is abnormal." [PomBase:mah] is_a: FYPO:0000330 ! abnormal histone modification intersection_of: PATO:0000001 intersection_of: inheres_in GO:0016575 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000202 name: abnormal regulation of cytokinetic cell separation def: "A regulation phenotype in which regulation of cytokinetic cell separation is abnormal." [PomBase:mah] is_a: FYPO:0000145 ! regulation phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0010590 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000203 name: abnormal ergosterol biosynthetic process def: "A metabolism phenotype in which ergosterol biosynthesis is abnormal." [PomBase:mah] synonym: "abnormal ergosterol biosynthesis" EXACT [PomBase:mah] is_a: FYPO:0000140 ! cellular metabolism phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0006696 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000204 name: abnormal mRNA export from nucleus def: "A transport phenotype in which the export of mRNA from the nucleus is abnormal." [PomBase:mah] is_a: FYPO:0000506 ! abnormal nuclear export intersection_of: PATO:0000001 intersection_of: inheres_in GO:0006406 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000205 name: DNA replication checkpoint activated def: "A cell cycle phenotype in which the DNA replication checkpoint is activated, i.e. the cell cycle is delayed or halted before nuclear division to allow DNA replication to be completed." [PomBase:mah] is_a: FYPO:0000137 ! cell cycle checkpoint phenotype created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000206 name: abnormal chromatin silencing at rDNA def: "A transcription regulation phenotype in which chromatin silencing at ribosomal DNA repeats is abnormal." [PomBase:mah] is_a: FYPO:0000144 ! abnormal chromatin silencing intersection_of: PATO:0000001 intersection_of: inheres_in GO:0000183 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000207 name: abnormal cellular response to caffeine def: "A chemical response phenotype in which the cellular response to caffeine is abnormal." [PomBase:mah] is_a: FYPO:0000298 ! cellular response phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0071313 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000208 name: abnormal cellular response to cadmium ion def: "A chemical response phenotype in which the cellular response to cadmium ions is abnormal." [PomBase:mah] is_a: FYPO:0000298 ! cellular response phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0071276 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000209 name: abnormal attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation def: "A cellular process phenotype in which the attachment of spindle microtubules to the kinetochore during the first meiotic division is abnormal." [PomBase:mah] is_a: FYPO:0000325 ! abnormal attachment of spindle microtubules to kinetochore intersection_of: PATO:0000001 intersection_of: inheres_in GO:0051455 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000211 name: abnormal response to drug def: "A chemical response phenotype in which the cellular response to a chemical is abnormal." [PomBase:mah] is_a: FYPO:0000298 ! cellular response phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0042493 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000212 name: abnormal cellular response to heat def: "A cellular response phenotype in which the cellular response to heat is abnormal." [PomBase:mah] is_a: FYPO:0000162 ! abnormal cellular response to stress intersection_of: PATO:0000001 intersection_of: inheres_in GO:0034605 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000213 name: abnormal vesicle-mediated transport def: "A transport phenotype in which vesicle-mediated transport is abnormal." [PomBase:mah] is_a: FYPO:0000149 ! transport phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0016192 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000214 name: abnormal mitotic chromosome condensation def: "A cellular process phenotype in which mitotic chromosome condensation is abnormal." [PomBase:mah] is_a: FYPO:0000159 ! abnormal chromosome condensation intersection_of: PATO:0000001 intersection_of: inheres_in GO:0007076 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000215 name: abnormal intracellular protein transport def: "A transport phenotype in which intracellular protein transport is abnormal." [PomBase:mah] is_a: FYPO:0000540 ! abnormal protein transport intersection_of: PATO:0000001 intersection_of: inheres_in GO:0006886 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000216 name: abnormal negative regulation of DNA replication initiation def: "A regulation phenotype in which negative regulation of DNA-dependent DNA replication initiation is abnormal, resulting in re-replication of all or part of the genome." [PomBase:mah] synonym: "abnormal negative regulation of DNA-dependent DNA replication initiation" EXACT [PomBase:mah] synonym: "DNA replication defects, endoreduplication" RELATED [PomBase:mah] is_a: FYPO:0000145 ! regulation phenotype is_a: FYPO:0000217 ! abnormal DNA replication intersection_of: PATO:0000001 intersection_of: inheres_in GO:0032297 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000217 name: abnormal DNA replication def: "A cellular process phenotype in which DNA replication is abnormal." [PomBase:mah] synonym: "abnormal DNA-dependent DNA replication" EXACT [PomBase:mah] is_a: FYPO:0000293 ! DNA metabolism phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0006261 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000218 name: decreased Mre11 complex assembly def: "A cellular process phenotype in which the occurrence of Mre11 complex assembly is reduced." [PomBase:mah] synonym: "MRN complex formation, reduced" EXACT [PomBase:mah] is_a: FYPO:0000447 ! abnormal protein complex assembly intersection_of: PATO:0002052 intersection_of: inheres_in GO:0072685 created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000219 name: increased protein oxidation def: "A cellular metabolism phenotype in which protein oxidation is increased, resulting in the accumulation of proteins with oxidative modifications including carbonylated proteins." [PomBase:mah] synonym: "accumulation of carbonylated proteins" RELATED [PomBase:mah] is_a: FYPO:0000547 ! increased protein modification intersection_of: PATO:0002051 intersection_of: inheres_in GO:0018158 created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000220 name: accumulation of non-coding outer repeat transcripts def: "A cellular metabolism phenotype in which small interfering RNA transcripts derived from the centromere outer repeat region are present at greater levels than normal." [PMID:20211136, PomBase:mah] is_a: FYPO:0000140 ! cellular metabolism phenotype created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000221 name: transcription regulation phenotype, adaptive response to loss of mtDNA def: "A transcription regulation phenotype in which the transcription of specific genes is regulated in response to the loss of mitochondrial DNA." [PMID:17868468, PomBase:mah] synonym: "adaptive expression responses" EXACT [PomBase:mah] is_a: FYPO:0000143 ! transcription regulation phenotype created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000222 name: slow aerobic cell growth def: "A cellular process phenotype in which cell growth is slower than normal under aerobic conditions." [PomBase:mah] synonym: "aerobic growth defects" EXACT [PomBase:mah] is_a: FYPO:0000046 ! slow cell growth intersection_of: PATO:0001459 intersection_of: inheres_in GO:0016049 created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000223 name: elongated, multiseptate cells def: "A cell morphology phenotype in which cells are elongated and have more than one septum per cell." [PomBase:mah] is_a: FYPO:0000017 ! elongated cells is_a: FYPO:0000118 ! multiseptate intersection_of: has_part FYPO:0000017 ! elongated cells intersection_of: has_part FYPO:0000118 ! multiseptate created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000224 name: lemon-shaped def: "A cell morphology phenotype in which a single cell grows in the form of a lemon. A lemon shape is defined mathematically as having a quadric surface in three dimensions obtained by rotating less than half of a circular arc about an axis passing through the endpoints of the arc." [http://mathworld.wolfram.com/Lemon.html, PomBase:mah] synonym: "cell morphology, lemon shaped" EXACT [PomBase:mah] is_a: FYPO:0000005 ! abnormal cell morphology created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000225 name: snowman during sporulation def: "A cell morphology phenotype in which a cell undregoing sporulation assumes a snowman shape, having two connected parts, roughly spherical, of different sizes." [PomBase:mah] synonym: "cell morphology, snowman during sporulation" EXACT [PomBase:mah] is_a: FYPO:0000005 ! abnormal cell morphology created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000227 name: chromosome loss upon segregation def: "A chromosome segregation phenotype in which one or more chromosome or minichromosome is not correctly segregated to either daughter cells." [PMID:11809834, PMID:20211136, PomBase:mah] synonym: "chromosome segregation defects, chromosome loss" EXACT [PomBase:mah] is_a: FYPO:0000029 ! abnormal chromosome segregation created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000228 name: lagging chromosomes def: "A chromosome segregation phenotype in which chromosomes do not move towards the spindle poles at the same time, but instead one or more chromosomes remain distant from the spindle pole after the bulk of the DNA has segregated." [PMID:11809834, PMID:20211136, PomBase:mah] synonym: "chromosome segregation defects, lagging chromosomes" EXACT [PomBase:mah] is_a: FYPO:0000029 ! abnormal chromosome segregation created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000229 name: cut def: "An inviable phenotype in which a cell undergoes septation despite abnormal chromosome segregation, and gives rise to inviable daughter cells." [PomBase:mah, PomBase:vw, PomBse:jh] is_a: FYPO:0000029 ! abnormal chromosome segregation created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000230 name: abnormal contractile ring actin filament organization def: "A cytokinesis phenotype in which the assembly and distribution of actin filament bundles does not occur normally, resulting in the formation of an abnormal contractile ring in which actin is absent or mislocalized." [PMID:19713940, PomBase:mah] synonym: "cytokinesis defects, contractile ring actin, absent" RELATED [PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis is_a: FYPO:0000296 ! actin cytoskeleton organization phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:2000689 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000231 name: abnormal contractile ring myosin filament organization def: "A cytokinesis phenotype in which myosin filaments are not localized normally within the contractile ring." [PMID:19713940, PomBase:mah] synonym: "cytokinesis defects, contractile ring myosin distribution, defective" RELATED [PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis is_a: FYPO:0000296 ! actin cytoskeleton organization phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:2000708 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000232 name: actomyosin contractile ring splitting def: "A cytokinesis phenotype in which the contractile ring splits upon initiation of contraction, resulting in the formation of a primary ring that undergoes constriction and a secondary ring that does not constrict." [PMID:18272786, PomBase:mah] synonym: "cytokinesis defects, splitting of the actinomyosin ring" RELATED [PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis intersection_of: PATO:0000001 intersection_of: inheres_in GO:0000916 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000233 name: long cytoplasmic microtubules def: "A microtubule organization phenotype in which cells form cytoplasmic microtubules that are longer than normal." [PomBase:mah] synonym: "microtubule organization defect, long cytoplasmic microtubules" EXACT [PomBase:mah] synonym: "microtubule organization defects, long cytoplasmic microtubules" EXACT [PomBase:mah] is_a: FYPO:0000055 ! long microtubules intersection_of: PATO:0000573 intersection_of: inheres_in GO:0005881 created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000234 name: abnormal interphase microtubule nucleation def: "A microtubule cytoskeleton organization phenotype in which nucleation of microtubules from interphase microtubule organizing centers (iMTOCs) is abnormal." [PMID:19001497, PomBase:mah] synonym: "abnormal interphase microtubule nucleation by interphase microtubule organizing center" EXACT [PomBase:mah] synonym: "cytoskeletal defects, cytoplasmic microtubule nucleation defects, Non-SPB" RELATED [PomBase:mah] is_a: FYPO:0000297 ! microtubule cytoskeleton organization phenotype intersection_of: PATO:0000001 intersection_of: inheres_in GO:0051415 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000235 name: abnormal regulation of translation in response to osmotic stress def: "A gene expression phenotype in which regulation of translation in response to osmotic stress is abnormal. Translation may be down-regulated to a greater extent than normal, and may not be restored to normal levels post-stress." [PMID:18065650, PomBase:mah] synonym: "defective in recovery of translation after hyperosmotic shock" RELATED [PomBase:mah] is_a: FYPO:0000263 ! abnormal regulation of translation in response to stress intersection_of: PATO:0000001 intersection_of: inheres_in GO:0043557 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000236 name: abnormal regulation of translation in response to oxidative stress def: "A gene expression phenotype in which regulation of translation in response to oxidative stress is abnormal. Translation may be down-regulated to a greater extent than normal, and may not be restored to normal levels post-stress." [PMID:18065650, PomBase:mah] synonym: "defective in recovery of translation after oxidative stress" RELATED [PomBase:mah] is_a: FYPO:0000180 ! abnormal cellular response to oxidative stress is_a: FYPO:0000263 ! abnormal regulation of translation in response to stress intersection_of: PATO:0000001 intersection_of: inheres_in GO:0043556 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000237 name: abnormal regulation of translation in response to nitrogen starvation def: "A gene expression phenotype in which regulation of translation in response to nitrogen starvation is abnormal. Translation may be down-regulated to a greater extent than normal, and may not be restored to normal levels upon prolonged nitrogen starvation." [PMID:18065650, PomBase:mah] synonym: "defective in recovery of translation during nitrogen starvation" RELATED [PomBase:mah] is_a: FYPO:0000152 ! abnormal cellular response to nitrogen starvation is_a: FYPO:0000263 ! abnormal regulation of translation in response to stress intersection_of: PATO:0000001 intersection_of: inheres_in GO:0070321 intersection_of: qualifier PATO:0000460 created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000238 name: inviable upon G0 to G1 transition def: "A cell phenotype in which cells fail to resume growth after several days in G0 phase. The inviable cells show some features characteristic of apoptosis, including loss of DNA." [PMID:19197239, PomBase:mah] synonym: "die in G0 with an apoptotic-like phenotype" EXACT [PomBase:mah] is_a: FYPO:0000002 ! cell phenotype intersection_of: PATO:0001558 intersection_of: inheres_in GO:0045023 created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000239 name: expression of MBF target genes increased def: "A gene expression phenotype in which transcription of genes that are regulated by MBF (the MluI cell cycle box factor) is increased." [PomBase:mah] is_a: FYPO:0000142 ! gene expression phenotype created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000240 name: abnormal filament morphology def: "A cell population phenotype in which the morphology of invasively growing filaments is abnormal." [PomBase:mah] synonym: "filament morphology aberrant" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000241 name: genome stability defects def: "A cell phenotype in which any process that affects the physical integrity, replication, or segregation of genomic DNA is abnormal. Encompasses effects on DNA metabolism, chromosome organization, the spindle assembly checkpoint, and any DNA integrity checkpoint." [PomBase:jh, PomBase:mah, PomBase:vw] comment: Consider annotating to 'abnormal chromosome organization' (FYPO:0000641), 'DNA metabolism phenotype' (FYPO:0000293) or any of its children, 'abnormal mitotic cell cycle spindle assembly checkpoint' (FYPO:0000168), or 'abnormal DNA integrity checkpoint' (FYPO:0000643) or any of its children. is_a: FYPO:0000002 ! cell phenotype created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000242 name: normal cell growth on ammonia nitrogen source def: "A cell growth phenotype in which cells grow at a normal rate in a medium containing ammonia as the nitrogen source." [PomBase:mah] synonym: "growth defect, normal growth with ammonia nitrogen source" RELATED [PomBase:mah] is_a: FYPO:0000047 ! normal cell growth intersection_of: FYPO:0000047 ! normal cell growth intersection_of: inheres_in BTO:0000316 intersection_of: qualifier PATO:0000467 intersection_of: towards CHEBI:16134 created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000243 name: normal cell growth on proline nitrogen source def: "A cell growth phenotype in which cells grow at a normal rate in a medium containing L-proline as the nitrogen source." [PomBase:mah] synonym: "growth defect, normal growth with proline nitrogen source" RELATED [PomBase:mah] is_a: FYPO:0000047 ! normal cell growth intersection_of: FYPO:0000047 ! normal cell growth intersection_of: inheres_in BTO:0000316 intersection_of: qualifier PATO:0000467 intersection_of: towards CHEBI:17203 created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000244 name: loss of viability upon nutrient depletion def: "A cell population phenotype in which a smaller than normal proportion of the population remains viable when cells are deprived of nutrients such as carbon or nitrogen." [PomBase:mah] synonym: "growth defect, required during nutrient depletion" RELATED [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype