<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
158
</numberChangedClasses>
<numberNewClasses>
56
</numberNewClasses>
<numberDeletedClasses>
23
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CARO_0000006</classIRI>
<classLabel>material anatomical entity</classLabel>
<deletedAxiom>&apos;material anatomical entity&apos; SubClassOf &apos;drains&apos; only &apos;connected anatomical structure&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002405</classIRI>
<classLabel>immune system</classLabel>
<deletedAxiom>&apos;renal system&apos; DisjointWith &apos;immune system&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002402</classIRI>
<classLabel>pleural cavity</classLabel>
<deletedAxiom>&apos;pleural cavity&apos; SubClassOf &apos;develops from&apos; some &apos;intraembryonic coelom&apos;</deletedAxiom>
<newAxiom>&apos;pleural cavity&apos; SubClassOf &apos;develops from&apos; some &apos;intraembryonic coelom&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002416</classIRI>
<classLabel>integumental system</classLabel>
<deletedAxiom>&apos;renal system&apos; DisjointWith &apos;integumental system&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002423</classIRI>
<classLabel>hepatobiliary system</classLabel>
<deletedAxiom>&apos;renal system&apos; DisjointWith &apos;hepatobiliary system&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001159</classIRI>
<classLabel>sigmoid colon</classLabel>
<deletedAxiom>&apos;sigmoid colon&apos; SubClassOf &apos;develops from&apos; some &apos;hindgut&apos;</deletedAxiom>
<newAxiom>&apos;sigmoid colon&apos; SubClassOf &apos;develops from&apos; some &apos;hindgut&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001165</classIRI>
<classLabel>pyloric antrum</classLabel>
<deletedAxiom>&apos;pyloric antrum&apos; SubClassOf &apos;part of&apos; some &apos;pylorus&apos;</deletedAxiom>
<newAxiom>&apos;pyloric antrum&apos; SubClassOf &apos;part of&apos; some &apos;pylorus&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001179</classIRI>
<classLabel>peritoneal cavity</classLabel>
<deletedAxiom>&apos;peritoneal cavity&apos; SubClassOf &apos;develops from&apos; some &apos;intraembryonic coelom&apos;</deletedAxiom>
<newAxiom>&apos;peritoneal cavity&apos; SubClassOf &apos;develops from&apos; some &apos;intraembryonic coelom&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001175</classIRI>
<classLabel>common hepatic duct</classLabel>
<deletedAxiom>&apos;common hepatic duct&apos; SubClassOf &apos;continuous with&apos; some &apos;left hepatic duct&apos;</deletedAxiom>
<deletedAxiom>&apos;common hepatic duct&apos; SubClassOf &apos;continuous with&apos; some &apos;right hepatic duct&apos;</deletedAxiom>
<newAxiom>&apos;common hepatic duct&apos; SubClassOf &apos;continuous with&apos; some &apos;left hepatic duct&apos;</newAxiom>
<newAxiom>&apos;common hepatic duct&apos; SubClassOf &apos;continuous with&apos; some &apos;right hepatic duct&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010851</classIRI>
<classLabel>cyclase regulator activity</classLabel>
<deletedAxiom>&apos;cyclase regulator activity&apos; SubClassOf &apos;part of&apos; some &apos;regulation of cyclase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010856</classIRI>
<classLabel>adenylate cyclase activator activity</classLabel>
<deletedAxiom>&apos;adenylate cyclase activator activity&apos; EquivalentTo &apos;enzyme activator activity&apos; and (&apos;positively regulates&apos; some &apos;adenylate cyclase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;adenylate cyclase activator activity&apos; SubClassOf &apos;enzyme activator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;adenylate cyclase activator activity&apos; SubClassOf &apos;cyclase regulator activity&apos;</deletedAxiom>
<newAxiom>&apos;adenylate cyclase activator activity&apos; EquivalentTo &apos;molecular function activator activity&apos; and (&apos;positively regulates&apos; some &apos;adenylate cyclase activity&apos;)</newAxiom>
<newAxiom>&apos;adenylate cyclase activator activity&apos; SubClassOf &apos;adenylate cyclase regulator activity&apos;</newAxiom>
<newAxiom>&apos;adenylate cyclase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0010853</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010852</classIRI>
<classLabel>cyclase inhibitor activity</classLabel>
<deletedAxiom>&apos;cyclase inhibitor activity&apos; EquivalentTo &apos;enzyme regulator activity&apos; and (&apos;negatively regulates&apos; some &apos;cyclase activity&apos;)</deletedAxiom>
<newAxiom>&apos;cyclase inhibitor activity&apos; EquivalentTo http://purl.obolibrary.org/obo/GO_0140678 and (&apos;negatively regulates&apos; some &apos;cyclase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010854</classIRI>
<classLabel>adenylate cyclase regulator activity</classLabel>
<deletedAxiom>&apos;adenylate cyclase regulator activity&apos; SubClassOf &apos;cyclase inhibitor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;adenylate cyclase regulator activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;negatively regulates&apos; some &apos;adenylate cyclase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;adenylate cyclase regulator activity&apos; SubClassOf &apos;negatively regulates&apos; some &apos;adenylate cyclase activity&apos;</deletedAxiom>
<newAxiom>&apos;adenylate cyclase regulator activity&apos; SubClassOf &apos;cyclase regulator activity&apos;</newAxiom>
<newAxiom>&apos;adenylate cyclase regulator activity&apos; SubClassOf &apos;regulates&apos; some &apos;adenylate cyclase activity&apos;</newAxiom>
<newAxiom>&apos;adenylate cyclase regulator activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;regulates&apos; some &apos;adenylate cyclase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019209</classIRI>
<classLabel>kinase activator activity</classLabel>
<newAxiom>&apos;kinase activator activity&apos; EquivalentTo &apos;molecular function activator activity&apos; and (&apos;positively regulates&apos; some &apos;kinase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046811</classIRI>
<classLabel>histone deacetylase inhibitor activity</classLabel>
<deletedAxiom>&apos;histone deacetylase inhibitor activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;negatively regulates&apos; some &apos;histone deacetylase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;histone deacetylase inhibitor activity&apos; SubClassOf &apos;part of&apos; some &apos;negative regulation of histone deacetylation&apos;</deletedAxiom>
<newAxiom>&apos;histone deacetylase inhibitor activity&apos; EquivalentTo http://purl.obolibrary.org/obo/GO_0140678 and (&apos;negatively regulates&apos; some &apos;histone deacetylase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019210</classIRI>
<classLabel>kinase inhibitor activity</classLabel>
<newAxiom>&apos;kinase inhibitor activity&apos; EquivalentTo http://purl.obolibrary.org/obo/GO_0140678 and (&apos;negatively regulates&apos; some &apos;kinase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019211</classIRI>
<classLabel>phosphatase activator activity</classLabel>
<deletedAxiom>&apos;phosphatase activator activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;positively regulates&apos; some &apos;phosphatase activity&apos;)</deletedAxiom>
<newAxiom>&apos;phosphatase activator activity&apos; EquivalentTo &apos;molecular function activator activity&apos; and (&apos;positively regulates&apos; some &apos;phosphatase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019212</classIRI>
<classLabel>phosphatase inhibitor activity</classLabel>
<deletedAxiom>&apos;phosphatase inhibitor activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;negatively regulates&apos; some &apos;phosphatase activity&apos;)</deletedAxiom>
<newAxiom>&apos;phosphatase inhibitor activity&apos; EquivalentTo http://purl.obolibrary.org/obo/GO_0140678 and (&apos;negatively regulates&apos; some &apos;phosphatase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001007</classIRI>
<classLabel>digestive system</classLabel>
<deletedAxiom>&apos;digestive system&apos; DisjointWith &apos;renal system&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001008</classIRI>
<classLabel>renal system</classLabel>
<deletedAxiom>&apos;renal system&apos; DisjointWith &apos;entire sense organ system&apos;</deletedAxiom>
<deletedAxiom>&apos;renal system&apos; DisjointWith &apos;circulatory system&apos;</deletedAxiom>
<deletedAxiom>&apos;respiratory system&apos; DisjointWith &apos;renal system&apos;</deletedAxiom>
<deletedAxiom>&apos;renal system&apos; DisjointWith &apos;hematopoietic system&apos;</deletedAxiom>
<deletedAxiom>&apos;renal system&apos; EquivalentTo &apos;anatomical system&apos; and (&apos;capable of&apos; some &apos;excretion&apos;)</deletedAxiom>
<deletedAxiom>&apos;renal system&apos; DisjointWith &apos;biliary system&apos;</deletedAxiom>
<deletedAxiom>&apos;renal system&apos; DisjointWith &apos;exocrine system&apos;</deletedAxiom>
<deletedAxiom>&apos;reproductive system&apos; DisjointWith &apos;renal system&apos;</deletedAxiom>
<deletedAxiom>&apos;renal system&apos; DisjointWith &apos;immune system&apos;</deletedAxiom>
<deletedAxiom>&apos;renal system&apos; DisjointWith &apos;skeletal system&apos;</deletedAxiom>
<deletedAxiom>&apos;renal system&apos; DisjointWith &apos;musculoskeletal system&apos;</deletedAxiom>
<deletedAxiom>&apos;renal system&apos; DisjointWith &apos;nervous system&apos;</deletedAxiom>
<deletedAxiom>&apos;renal system&apos; DisjointWith &apos;integumental system&apos;</deletedAxiom>
<deletedAxiom>&apos;digestive system&apos; DisjointWith &apos;renal system&apos;</deletedAxiom>
<deletedAxiom>&apos;renal system&apos; DisjointWith &apos;hepatobiliary system&apos;</deletedAxiom>
<deletedAxiom>&apos;endocrine system&apos; DisjointWith &apos;renal system&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001009</classIRI>
<classLabel>circulatory system</classLabel>
<deletedAxiom>&apos;renal system&apos; DisjointWith &apos;circulatory system&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001004</classIRI>
<classLabel>respiratory system</classLabel>
<deletedAxiom>&apos;respiratory system&apos; DisjointWith &apos;renal system&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002330</classIRI>
<classLabel>exocrine system</classLabel>
<deletedAxiom>&apos;renal system&apos; DisjointWith &apos;exocrine system&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001016</classIRI>
<classLabel>nervous system</classLabel>
<deletedAxiom>&apos;renal system&apos; DisjointWith &apos;nervous system&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002390</classIRI>
<classLabel>hematopoietic system</classLabel>
<deletedAxiom>&apos;renal system&apos; DisjointWith &apos;hematopoietic system&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001074</classIRI>
<classLabel>pericardial cavity</classLabel>
<deletedAxiom>&apos;pericardial cavity&apos; SubClassOf &apos;develops from&apos; some &apos;intraembryonic coelom&apos;</deletedAxiom>
<newAxiom>&apos;pericardial cavity&apos; SubClassOf &apos;develops from&apos; some &apos;intraembryonic coelom&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001046</classIRI>
<classLabel>hindgut</classLabel>
<deletedAxiom>&apos;hindgut&apos; SubClassOf &apos;develops from&apos; some &apos;mesenchyme&apos;</deletedAxiom>
<newAxiom>&apos;hindgut&apos; SubClassOf &apos;develops from&apos; some &apos;mesenchyme&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002204</classIRI>
<classLabel>musculoskeletal system</classLabel>
<deletedAxiom>&apos;renal system&apos; DisjointWith &apos;musculoskeletal system&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002294</classIRI>
<classLabel>biliary system</classLabel>
<deletedAxiom>&apos;renal system&apos; DisjointWith &apos;biliary system&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002104</classIRI>
<classLabel>visual system</classLabel>
<deletedAxiom>&apos;visual system&apos; SubClassOf &apos;capable of&apos; some &apos;visual perception&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033238</classIRI>
<classLabel>regulation of cellular amine metabolic process</classLabel>
<newAxiom>&apos;regulation of cellular amine metabolic process&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;amine metabolic process&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033239</classIRI>
<classLabel>negative regulation of cellular amine metabolic process</classLabel>
<newAxiom>&apos;negative regulation of cellular amine metabolic process&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;amine metabolic process&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033240</classIRI>
<classLabel>positive regulation of cellular amine metabolic process</classLabel>
<newAxiom>&apos;positive regulation of cellular amine metabolic process&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;amine metabolic process&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071575</classIRI>
<classLabel>integral component of external side of plasma membrane</classLabel>
<deletedAxiom>&apos;integral component of external side of plasma membrane&apos; EquivalentTo &apos;integral component of membrane&apos; and (&apos;part of&apos; some &apos;external side of plasma membrane&apos;)</deletedAxiom>
<deletedAxiom>&apos;integral component of external side of plasma membrane&apos; SubClassOf &apos;intrinsic component of external side of plasma membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;integral component of external side of plasma membrane&apos; SubClassOf &apos;integral component of plasma membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035800</classIRI>
<classLabel>deubiquitinase activator activity</classLabel>
<deletedAxiom>&apos;deubiquitinase activator activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;positively regulates&apos; some &apos;deubiquitinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;deubiquitinase activator activity&apos; SubClassOf &apos;part of&apos; some &apos;positive regulation of ubiquitin-specific protease activity&apos;</deletedAxiom>
<newAxiom>&apos;deubiquitinase activator activity&apos; EquivalentTo &apos;molecular function activator activity&apos; and (&apos;positively regulates&apos; some &apos;deubiquitinase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001645</classIRI>
<classLabel>trigeminal nerve</classLabel>
<deletedAxiom>&apos;trigeminal nerve&apos; SubClassOf &apos;has developmental contribution from&apos; some &apos;basal plate metencephalon&apos;</deletedAxiom>
<newAxiom>&apos;trigeminal nerve&apos; SubClassOf &apos;has developmental contribution from&apos; some &apos;basal plate metencephalon&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008047</classIRI>
<classLabel>enzyme activator activity</classLabel>
<newAxiom>&apos;enzyme activator activity&apos; EquivalentTo &apos;molecular function activator activity&apos; and (&apos;positively regulates&apos; some &apos;catalytic activity&apos;)</newAxiom>
<newAxiom>&apos;enzyme activator activity&apos; SubClassOf &apos;molecular function activator activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0013411</classIRI>
<classLabel>cranial cavity</classLabel>
<deletedAxiom>&apos;cranial cavity&apos; SubClassOf &apos;part of&apos; some &apos;skull&apos;</deletedAxiom>
<newAxiom>&apos;cranial cavity&apos; SubClassOf &apos;part of&apos; some &apos;skull&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000104</classIRI>
<classLabel>life cycle</classLabel>
<deletedAxiom>&apos;life cycle&apos; SubClassOf &apos;starts with&apos; some &apos;zygote stage&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001434</classIRI>
<classLabel>skeletal system</classLabel>
<deletedAxiom>&apos;renal system&apos; DisjointWith &apos;skeletal system&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001514</classIRI>
<classLabel>descending aorta</classLabel>
<deletedAxiom>&apos;descending aorta&apos; SubClassOf &apos;develops from&apos; some &apos;dorsal aorta&apos;</deletedAxiom>
<newAxiom>&apos;descending aorta&apos; SubClassOf &apos;develops from&apos; some &apos;dorsal aorta&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001530</classIRI>
<classLabel>common carotid artery plus branches</classLabel>
<deletedAxiom>&apos;common carotid artery plus branches&apos; SubClassOf &apos;develops from&apos; some &apos;pharyngeal arch artery&apos;</deletedAxiom>
<newAxiom>&apos;common carotid artery plus branches&apos; SubClassOf &apos;develops from&apos; some &apos;pharyngeal arch artery&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000012</classIRI>
<classLabel>somatic nervous system</classLabel>
<deletedAxiom>&apos;somatic nervous system&apos; SubClassOf &apos;contributes to morphology of&apos; some &apos;nervous system&apos;</deletedAxiom>
<deletedAxiom>&apos;somatic nervous system&apos; SubClassOf &apos;organ system subdivision&apos;</deletedAxiom>
<deletedAxiom>&apos;somatic nervous system&apos; SubClassOf &apos;part of&apos; some &apos;peripheral nervous system&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000818</classIRI>
<classLabel>nuclear MIS12/MIND complex</classLabel>
<deletedAxiom>&apos;nuclear MIS12/MIND complex&apos; SubClassOf &apos;MIS12/MIND type complex&apos;</deletedAxiom>
<deletedAxiom>&apos;nuclear MIS12/MIND complex&apos; SubClassOf &apos;nuclear protein-containing complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000091</classIRI>
<classLabel>bilaminar disc</classLabel>
<deletedAxiom>&apos;bilaminar disc&apos; SubClassOf &apos;develops from&apos; some &apos;inner cell mass&apos;</deletedAxiom>
<newAxiom>&apos;bilaminar disc&apos; SubClassOf &apos;develops from&apos; some &apos;inner cell mass&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000095</classIRI>
<classLabel>cardiac neural crest</classLabel>
<deletedAxiom>&apos;cardiac neural crest&apos; SubClassOf &apos;overlaps&apos; some &apos;vagal neural crest&apos;</deletedAxiom>
<newAxiom>&apos;cardiac neural crest&apos; SubClassOf &apos;overlaps&apos; some &apos;vagal neural crest&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072542</classIRI>
<classLabel>protein phosphatase activator activity</classLabel>
<deletedAxiom>&apos;protein phosphatase activator activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;positively regulates&apos; some &apos;phosphoprotein phosphatase activity&apos;)</deletedAxiom>
<newAxiom>&apos;protein phosphatase activator activity&apos; EquivalentTo &apos;molecular function activator activity&apos; and (&apos;positively regulates&apos; some &apos;phosphoprotein phosphatase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000087</classIRI>
<classLabel>inner cell mass</classLabel>
<deletedAxiom>&apos;inner cell mass&apos; SubClassOf &apos;surrounded by&apos; some &apos;trophoblast&apos;</deletedAxiom>
<deletedAxiom>&apos;inner cell mass&apos; SubClassOf &apos;develops from&apos; some &apos;blastocyst&apos;</deletedAxiom>
<newAxiom>&apos;inner cell mass&apos; SubClassOf &apos;surrounded by&apos; some &apos;trophoblast&apos;</newAxiom>
<newAxiom>&apos;inner cell mass&apos; SubClassOf &apos;develops from&apos; some &apos;blastocyst&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/FYPO_0005146</classIRI>
<classLabel>normal proteasome localization to nuclear periphery</classLabel>
<deletedAxiom>&apos;normal proteasome localization to nuclear periphery&apos; SubClassOf &apos;normal proteasome localization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003887</classIRI>
<classLabel>intraembryonic coelom</classLabel>
<deletedAxiom>&apos;intraembryonic coelom&apos; SubClassOf &apos;develops from&apos; some &apos;lateral plate mesoderm&apos;</deletedAxiom>
<newAxiom>&apos;intraembryonic coelom&apos; SubClassOf &apos;develops from&apos; some &apos;lateral plate mesoderm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003890</classIRI>
<classLabel>Mullerian duct</classLabel>
<deletedAxiom>&apos;Mullerian duct&apos; SubClassOf &apos;develops from&apos; some &apos;intermediate mesoderm&apos;</deletedAxiom>
<newAxiom>&apos;Mullerian duct&apos; SubClassOf &apos;develops from&apos; some &apos;intermediate mesoderm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000712</classIRI>
<classLabel>resolution of meiotic recombination intermediates</classLabel>
<deletedAxiom>&apos;resolution of meiotic recombination intermediates&apos; SubClassOf &apos;part of&apos; some &apos;meiotic chromosome separation&apos;</deletedAxiom>
<newAxiom>&apos;resolution of meiotic recombination intermediates&apos; SubClassOf &apos;part of&apos; some &apos;meiotic chromosome segregation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001264</classIRI>
<classLabel>pancreas</classLabel>
<deletedAxiom>&apos;pancreas&apos; SubClassOf &apos;has developmental contribution from&apos; some &apos;ventral pancreatic bud&apos;</deletedAxiom>
<deletedAxiom>&apos;pancreas&apos; SubClassOf &apos;has developmental contribution from&apos; some &apos;dorsal pancreatic bud&apos;</deletedAxiom>
<newAxiom>&apos;pancreas&apos; SubClassOf &apos;has developmental contribution from&apos; some &apos;ventral pancreatic bud&apos;</newAxiom>
<newAxiom>&apos;pancreas&apos; SubClassOf &apos;has developmental contribution from&apos; some &apos;dorsal pancreatic bud&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_59676</classIRI>
<classLabel>nystatins</classLabel>
<newAxiom>&apos;nystatins&apos; SubClassOf &apos;dicarboxylic acid monoester&apos;</newAxiom>
<newAxiom>&apos;nystatins&apos; SubClassOf &apos;aminoglycoside antibiotic&apos;</newAxiom>
<newAxiom>&apos;nystatins&apos; SubClassOf http://purl.obolibrary.org/obo/CHEBI_48121</newAxiom>
<newAxiom>&apos;nystatins&apos; SubClassOf &apos;polyol&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071072</classIRI>
<classLabel>negative regulation of phospholipid biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of phospholipid biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071071</classIRI>
<classLabel>regulation of phospholipid biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of phospholipid biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071073</classIRI>
<classLabel>positive regulation of phospholipid biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of phospholipid biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003921</classIRI>
<classLabel>pancreas primordium</classLabel>
<deletedAxiom>&apos;pancreas primordium&apos; SubClassOf &apos;develops from&apos; some &apos;endoderm&apos;</deletedAxiom>
<newAxiom>&apos;pancreas primordium&apos; SubClassOf &apos;develops from&apos; some &apos;endoderm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003942</classIRI>
<classLabel>somatic sensory system</classLabel>
<classLabel>somatosensory system</classLabel>
<deletedAxiom>&apos;somatic sensory system&apos; SubClassOf &apos;part of&apos; some &apos;somatic nervous system&apos;</deletedAxiom>
<deletedAxiom>&apos;somatic sensory system&apos; EquivalentTo &apos;sensory system&apos; and (&apos;part of&apos; some &apos;somatic nervous system&apos;)</deletedAxiom>
<deletedAxiom>&apos;somatic sensory system&apos; SubClassOf &apos;contributes to morphology of&apos; some &apos;somatic nervous system&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003909</classIRI>
<classLabel>sinusoid</classLabel>
<deletedAxiom>&apos;sinusoid&apos; SubClassOf &apos;fenestrated capillary&apos;</deletedAxiom>
<newAxiom>&apos;sinusoid&apos; SubClassOf &apos;fenestrated capillary&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009064</classIRI>
<classLabel>glutamine family amino acid metabolic process</classLabel>
<newAxiom>&apos;glutamine family amino acid metabolic process&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has primary input or output&apos; some &apos;glutamine family amino acid&apos;)</newAxiom>
<newAxiom>&apos;glutamine family amino acid metabolic process&apos; SubClassOf &apos;has primary input or output&apos; some &apos;glutamine family amino acid&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009065</classIRI>
<classLabel>glutamine family amino acid catabolic process</classLabel>
<newAxiom>&apos;glutamine family amino acid catabolic process&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary input&apos; some &apos;glutamine family amino acid&apos;)</newAxiom>
<newAxiom>&apos;glutamine family amino acid catabolic process&apos; SubClassOf &apos;has primary input&apos; some &apos;glutamine family amino acid&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_7660</classIRI>
<classLabel>nystatin</classLabel>
<deletedAxiom>&apos;nystatin&apos; SubClassOf &apos;carboxylic acid&apos;</deletedAxiom>
<deletedAxiom>&apos;nystatin&apos; SubClassOf &apos;nystatins&apos;</deletedAxiom>
<newAxiom>&apos;nystatin&apos; SubClassOf &apos;antibiotic antifungal drug&apos;</newAxiom>
<newAxiom>&apos;nystatin&apos; SubClassOf &apos;mixture&apos;</newAxiom>
<newAxiom>&apos;nystatin&apos; SubClassOf &apos;macrolide antibiotic&apos;</newAxiom>
<newAxiom>&apos;nystatin&apos; SubClassOf &apos;has_part&apos; some http://purl.obolibrary.org/obo/CHEBI_192979</newAxiom>
<newAxiom>&apos;nystatin&apos; SubClassOf &apos;has role&apos; some &apos;bacterial metabolite&apos;</newAxiom>
<newAxiom>&apos;nystatin&apos; SubClassOf &apos;has_part&apos; some http://purl.obolibrary.org/obo/CHEBI_473992</newAxiom>
<newAxiom>&apos;nystatin&apos; SubClassOf http://purl.obolibrary.org/obo/CHEBI_48121</newAxiom>
<newAxiom>&apos;nystatin&apos; SubClassOf &apos;polyol&apos;</newAxiom>
<newAxiom>&apos;nystatin&apos; SubClassOf &apos;dicarboxylic acid monoester&apos;</newAxiom>
<newAxiom>&apos;nystatin&apos; SubClassOf &apos;has_part&apos; some http://purl.obolibrary.org/obo/CHEBI_31927</newAxiom>
<newAxiom>&apos;nystatin&apos; SubClassOf &apos;aminoglycoside antibiotic&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098772</classIRI>
<classLabel>molecular function regulator activity</classLabel>
<newAxiom>&apos;molecular function regulator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;regulates&apos; some &apos;molecular_function&apos;)</newAxiom>
<newAxiom>&apos;molecular function regulator activity&apos; SubClassOf &apos;regulates&apos; some &apos;molecular_function&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001987</classIRI>
<classLabel>placenta</classLabel>
<deletedAxiom>&apos;placenta&apos; SubClassOf &apos;develops from&apos; some &apos;chorion membrane&apos;</deletedAxiom>
<newAxiom>&apos;placenta&apos; SubClassOf &apos;develops from&apos; some &apos;chorion membrane&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_16240</classIRI>
<classLabel>hydrogen peroxide</classLabel>
<deletedAxiom>&apos;hydrogen peroxide&apos; SubClassOf &apos;has role&apos; some &apos;oxidising agent&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000444</classIRI>
<classLabel>MIS12/MIND type complex</classLabel>
<deletedAxiom>&apos;MIS12/MIND type complex&apos; SubClassOf &apos;part of&apos; some &apos;kinetochore&apos;</deletedAxiom>
<deletedAxiom>&apos;MIS12/MIND type complex&apos; SubClassOf &apos;protein-containing complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/FYPO_0007503</classIRI>
<classLabel>abnormal histone demethylase activity</classLabel>
<newAxiom>&apos;abnormal histone demethylase activity&apos; SubClassOf &apos;abnormal histone modification&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035033</classIRI>
<classLabel>histone deacetylase regulator activity</classLabel>
<deletedAxiom>&apos;histone deacetylase regulator activity&apos; SubClassOf &apos;part of&apos; some &apos;regulation of histone deacetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035034</classIRI>
<classLabel>histone acetyltransferase regulator activity</classLabel>
<deletedAxiom>&apos;histone acetyltransferase regulator activity&apos; SubClassOf &apos;part of&apos; some &apos;regulation of histone acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/FYPO_0007472</classIRI>
<classLabel>abnormal histone turnover</classLabel>
<deletedAxiom>&apos;abnormal histone turnover&apos; SubClassOf &apos;abnormal chromatin organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001776</classIRI>
<classLabel>optic choroid</classLabel>
<deletedAxiom>&apos;optic choroid&apos; SubClassOf &apos;overlaps&apos; some &apos;posterior segment of eyeball&apos;</deletedAxiom>
<newAxiom>&apos;optic choroid&apos; SubClassOf &apos;overlaps&apos; some &apos;posterior segment of eyeball&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001777</classIRI>
<classLabel>substantia propria of cornea</classLabel>
<deletedAxiom>&apos;substantia propria of cornea&apos; SubClassOf &apos;develops from&apos; some &apos;mesenchyme derived from head neural crest&apos;</deletedAxiom>
<newAxiom>&apos;substantia propria of cornea&apos; SubClassOf &apos;develops from&apos; some &apos;mesenchyme derived from head neural crest&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001778</classIRI>
<classLabel>ciliary epithelium</classLabel>
<deletedAxiom>&apos;ciliary epithelium&apos; SubClassOf &apos;produces&apos; some &apos;aqueous humor of eyeball&apos;</deletedAxiom>
<newAxiom>&apos;ciliary epithelium&apos; SubClassOf &apos;produces&apos; some &apos;aqueous humor of eyeball&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001773</classIRI>
<classLabel>sclera</classLabel>
<deletedAxiom>&apos;sclera&apos; SubClassOf &apos;develops from&apos; some &apos;mesenchyme derived from head neural crest&apos;</deletedAxiom>
<newAxiom>&apos;sclera&apos; SubClassOf &apos;develops from&apos; some &apos;mesenchyme derived from head neural crest&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098573</classIRI>
<classLabel>intrinsic component of mitochondrial membrane</classLabel>
<deletedAxiom>&apos;intrinsic component of mitochondrial membrane&apos; EquivalentTo &apos;intrinsic component of membrane&apos; and (&apos;part of&apos; some &apos;mitochondrial membrane&apos;)</deletedAxiom>
<deletedAxiom>&apos;intrinsic component of mitochondrial membrane&apos; SubClassOf &apos;intrinsic component of organelle membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;intrinsic component of mitochondrial membrane&apos; SubClassOf &apos;part of&apos; some &apos;mitochondrial membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000708</classIRI>
<classLabel>myosin filament organization involved in cytokinetic actomyosin contractile ring assembly</classLabel>
<deletedAxiom>&apos;myosin filament organization involved in cytokinetic actomyosin contractile ring assembly&apos; SubClassOf &apos;part of&apos; some &apos;actomyosin contractile ring assembly&apos;</deletedAxiom>
<deletedAxiom>&apos;myosin filament organization involved in cytokinetic actomyosin contractile ring assembly&apos; SubClassOf &apos;cell cycle process&apos;</deletedAxiom>
<deletedAxiom>&apos;myosin filament organization involved in cytokinetic actomyosin contractile ring assembly&apos; EquivalentTo &apos;myosin filament organization&apos; and (&apos;part of&apos; some &apos;actomyosin contractile ring assembly&apos;)</deletedAxiom>
<deletedAxiom>&apos;myosin filament organization involved in cytokinetic actomyosin contractile ring assembly&apos; SubClassOf &apos;myosin filament organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061135</classIRI>
<classLabel>endopeptidase regulator activity</classLabel>
<deletedAxiom>&apos;endopeptidase regulator activity&apos; SubClassOf &apos;part of&apos; some &apos;regulation of endopeptidase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061133</classIRI>
<classLabel>endopeptidase activator activity</classLabel>
<deletedAxiom>&apos;endopeptidase activator activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;positively regulates&apos; some &apos;endopeptidase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;endopeptidase activator activity&apos; SubClassOf &apos;part of&apos; some &apos;positive regulation of endopeptidase activity&apos;</deletedAxiom>
<newAxiom>&apos;endopeptidase activator activity&apos; EquivalentTo &apos;molecular function activator activity&apos; and (&apos;positively regulates&apos; some &apos;endopeptidase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0010294</classIRI>
<classLabel>scleral endothelium</classLabel>
<deletedAxiom>&apos;scleral endothelium&apos; SubClassOf &apos;layer of sclera&apos;</deletedAxiom>
<newAxiom>&apos;scleral endothelium&apos; SubClassOf &apos;layer of sclera&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0010295</classIRI>
<classLabel>substantia propria of sclera</classLabel>
<deletedAxiom>&apos;substantia propria of sclera&apos; SubClassOf &apos;layer of sclera&apos;</deletedAxiom>
<newAxiom>&apos;substantia propria of sclera&apos; SubClassOf &apos;layer of sclera&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000949</classIRI>
<classLabel>endocrine system</classLabel>
<deletedAxiom>&apos;endocrine system&apos; DisjointWith &apos;renal system&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_142517</classIRI>
<classLabel>tschimganine</classLabel>
<deletedAxiom>&apos;tschimganine&apos; SubClassOf &apos;phenol&apos;</deletedAxiom>
<newAxiom>&apos;tschimganine&apos; SubClassOf &apos;has role&apos; some &apos;antimicrobial agent&apos;</newAxiom>
<newAxiom>&apos;tschimganine&apos; SubClassOf &apos;has role&apos; some &apos;geroprotector&apos;</newAxiom>
<newAxiom>&apos;tschimganine&apos; SubClassOf &apos;phenols&apos;</newAxiom>
<newAxiom>&apos;tschimganine&apos; SubClassOf &apos;has role&apos; some &apos;animal metabolite&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000990</classIRI>
<classLabel>reproductive system</classLabel>
<deletedAxiom>&apos;reproductive system&apos; DisjointWith &apos;renal system&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0010191</classIRI>
<classLabel>aortic system</classLabel>
<deletedAxiom>&apos;aortic system&apos; SubClassOf &apos;part of&apos; some &apos;systemic arterial system&apos;</deletedAxiom>
<newAxiom>&apos;aortic system&apos; SubClassOf &apos;part of&apos; some &apos;systemic arterial system&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/FYPO_0007002</classIRI>
<classLabel>normal histone exchange at silent mating-type cassette</classLabel>
<deletedAxiom>&apos;normal histone exchange at silent mating-type cassette&apos; SubClassOf &apos;normal chromatin organization during vegetative growth&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/FYPO_0007001</classIRI>
<classLabel>normal histone exchange at pericentric heterochromatin</classLabel>
<deletedAxiom>&apos;normal histone exchange at pericentric heterochromatin&apos; SubClassOf &apos;normal chromatin organization during vegetative growth&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/FYPO_0007000</classIRI>
<classLabel>normal histone exchange at transposable element</classLabel>
<deletedAxiom>&apos;normal histone exchange at transposable element&apos; SubClassOf &apos;normal chromatin organization during vegetative growth&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/FYPO_0007003</classIRI>
<classLabel>normal histone exchange at tRNA genes</classLabel>
<deletedAxiom>&apos;normal histone exchange at tRNA genes&apos; SubClassOf &apos;normal chromatin organization during vegetative growth&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004857</classIRI>
<classLabel>enzyme inhibitor activity</classLabel>
<newAxiom>&apos;enzyme inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140678</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004860</classIRI>
<classLabel>protein kinase inhibitor activity</classLabel>
<newAxiom>&apos;protein kinase inhibitor activity&apos; EquivalentTo http://purl.obolibrary.org/obo/GO_0140678 and (&apos;negatively regulates&apos; some &apos;protein kinase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004864</classIRI>
<classLabel>protein phosphatase inhibitor activity</classLabel>
<deletedAxiom>&apos;protein phosphatase inhibitor activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;negatively regulates&apos; some &apos;phosphoprotein phosphatase activity&apos;)</deletedAxiom>
<newAxiom>&apos;protein phosphatase inhibitor activity&apos; EquivalentTo http://purl.obolibrary.org/obo/GO_0140678 and (&apos;negatively regulates&apos; some &apos;phosphoprotein phosphatase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004865</classIRI>
<classLabel>protein serine/threonine phosphatase inhibitor activity</classLabel>
<deletedAxiom>&apos;protein serine/threonine phosphatase inhibitor activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;negatively regulates&apos; some &apos;protein serine/threonine phosphatase activity&apos;)</deletedAxiom>
<newAxiom>&apos;protein serine/threonine phosphatase inhibitor activity&apos; EquivalentTo http://purl.obolibrary.org/obo/GO_0140678 and (&apos;negatively regulates&apos; some &apos;protein serine/threonine phosphatase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004866</classIRI>
<classLabel>endopeptidase inhibitor activity</classLabel>
<deletedAxiom>&apos;endopeptidase inhibitor activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;negatively regulates&apos; some &apos;endopeptidase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;endopeptidase inhibitor activity&apos; SubClassOf &apos;part of&apos; some &apos;negative regulation of endopeptidase activity&apos;</deletedAxiom>
<newAxiom>&apos;endopeptidase inhibitor activity&apos; EquivalentTo http://purl.obolibrary.org/obo/GO_0140678 and (&apos;negatively regulates&apos; some &apos;endopeptidase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004869</classIRI>
<classLabel>cysteine-type endopeptidase inhibitor activity</classLabel>
<deletedAxiom>&apos;cysteine-type endopeptidase inhibitor activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;negatively regulates&apos; some &apos;cysteine-type endopeptidase activity&apos;)</deletedAxiom>
<newAxiom>&apos;cysteine-type endopeptidase inhibitor activity&apos; EquivalentTo http://purl.obolibrary.org/obo/GO_0140678 and (&apos;negatively regulates&apos; some &apos;cysteine-type endopeptidase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0007196</classIRI>
<classLabel>tracheobronchial tree</classLabel>
<deletedAxiom>&apos;tracheobronchial tree&apos; SubClassOf &apos;has_part&apos; some &apos;ciliated columnar epithelium&apos;</deletedAxiom>
<newAxiom>&apos;tracheobronchial tree&apos; SubClassOf &apos;has_part&apos; some &apos;ciliated columnar epithelium&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015453</classIRI>
<classLabel>oxidoreduction-driven active transmembrane transporter activity</classLabel>
<newAxiom>&apos;oxidoreduction-driven active transmembrane transporter activity&apos; EquivalentTo &apos;primary active transmembrane transporter activity&apos; and (&apos;has_part&apos; some &apos;oxidoreductase activity&apos;)</newAxiom>
<newAxiom>&apos;oxidoreduction-driven active transmembrane transporter activity&apos; SubClassOf &apos;has_part&apos; some &apos;oxidoreductase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015399</classIRI>
<classLabel>primary active transmembrane transporter activity</classLabel>
<newAxiom>&apos;primary active transmembrane transporter activity&apos; SubClassOf &apos;has_part&apos; some &apos;catalytic activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990873</classIRI>
<classLabel>intrinsic component of plasma membrane of cell tip</classLabel>
<deletedAxiom>&apos;intrinsic component of plasma membrane of cell tip&apos; SubClassOf &apos;part of&apos; some &apos;plasma membrane of cell tip&apos;</deletedAxiom>
<deletedAxiom>&apos;intrinsic component of plasma membrane of cell tip&apos; EquivalentTo &apos;intrinsic component of membrane&apos; and (&apos;part of&apos; some &apos;plasma membrane of cell tip&apos;)</deletedAxiom>
<deletedAxiom>&apos;intrinsic component of plasma membrane of cell tip&apos; SubClassOf &apos;intrinsic component of plasma membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/FYPO_0000231</classIRI>
<classLabel>abnormal actomyosin contractile ring myosin filament organization</classLabel>
<deletedAxiom>&apos;abnormal actomyosin contractile ring myosin filament organization&apos; SubClassOf &apos;abnormal actomyosin contractile ring organization&apos;</deletedAxiom>
<newAxiom>&apos;abnormal actomyosin contractile ring myosin filament organization&apos; SubClassOf &apos;abnormal actin cytoskeleton organization during vegetative growth&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016504</classIRI>
<classLabel>peptidase activator activity</classLabel>
<newAxiom>&apos;peptidase activator activity&apos; EquivalentTo &apos;molecular function activator activity&apos; and (&apos;positively regulates&apos; some &apos;peptidase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990920</classIRI>
<classLabel>proteasome localization to nuclear periphery</classLabel>
<deletedAxiom>&apos;proteasome localization to nuclear periphery&apos; SubClassOf &apos;proteasome localization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990919</classIRI>
<classLabel>proteasome-nuclear membrane anchor activity</classLabel>
<deletedAxiom>&apos;proteasome-nuclear membrane anchor activity&apos; SubClassOf &apos;protein-membrane adaptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;proteasome-nuclear membrane anchor activity&apos; EquivalentTo &apos;protein-membrane adaptor activity&apos; and (&apos;part of&apos; some &apos;proteasome localization to nuclear periphery&apos;)</deletedAxiom>
<deletedAxiom>&apos;proteasome-nuclear membrane anchor activity&apos; SubClassOf &apos;part of&apos; some &apos;proteasome localization to nuclear periphery&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004402</classIRI>
<classLabel>histone acetyltransferase activity</classLabel>
<deletedAxiom>&apos;histone acetyltransferase activity&apos; SubClassOf &apos;part of&apos; some &apos;histone acetylation&apos;</deletedAxiom>
<newAxiom>&apos;histone acetyltransferase activity&apos; SubClassOf &apos;part of&apos; some &apos;histone modification&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004407</classIRI>
<classLabel>histone deacetylase activity</classLabel>
<newAxiom>&apos;histone deacetylase activity&apos; SubClassOf &apos;part of&apos; some &apos;histone modification&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0006239</classIRI>
<classLabel>future central tendon</classLabel>
<deletedAxiom>&apos;future central tendon&apos; SubClassOf &apos;develops from&apos; some &apos;septum transversum&apos;</deletedAxiom>
<newAxiom>&apos;future central tendon&apos; SubClassOf &apos;develops from&apos; some &apos;septum transversum&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0006242</classIRI>
<classLabel>gall bladder primordium</classLabel>
<classLabel>gallbladder primordium</classLabel>
<deletedAxiom>&apos;gall bladder primordium&apos; SubClassOf &apos;part of&apos; some &apos;biliary tree&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0008858</classIRI>
<classLabel>pyloric canal</classLabel>
<deletedAxiom>&apos;pyloric canal&apos; SubClassOf &apos;part of&apos; some &apos;pylorus&apos;</deletedAxiom>
<newAxiom>&apos;pyloric canal&apos; SubClassOf &apos;part of&apos; some &apos;pylorus&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0006207</classIRI>
<classLabel>aortico-pulmonary spiral septum</classLabel>
<deletedAxiom>&apos;aortico-pulmonary spiral septum&apos; SubClassOf &apos;develops from&apos; some &apos;cardiac neural crest&apos;</deletedAxiom>
<newAxiom>&apos;aortico-pulmonary spiral septum&apos; SubClassOf &apos;develops from&apos; some &apos;cardiac neural crest&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005639</classIRI>
<classLabel>integral component of nuclear inner membrane</classLabel>
<deletedAxiom>&apos;integral component of nuclear inner membrane&apos; SubClassOf &apos;integral component of organelle membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;integral component of nuclear inner membrane&apos; SubClassOf &apos;intrinsic component of nuclear inner membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;integral component of nuclear inner membrane&apos; EquivalentTo &apos;integral component of membrane&apos; and (&apos;part of&apos; some &apos;nuclear inner membrane&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0008780</classIRI>
<classLabel>inner cell mass derived epiblast</classLabel>
<deletedAxiom>&apos;inner cell mass derived epiblast&apos; SubClassOf &apos;develops from&apos; some &apos;inner cell mass&apos;</deletedAxiom>
<newAxiom>&apos;inner cell mass derived epiblast&apos; SubClassOf &apos;develops from&apos; some &apos;inner cell mass&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900049</classIRI>
<classLabel>regulation of histone exchange</classLabel>
<deletedAxiom>&apos;regulation of histone exchange&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;histone exchange&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of histone exchange&apos; SubClassOf &apos;regulation of chromatin organization&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone exchange&apos; SubClassOf &apos;regulates&apos; some &apos;histone exchange&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900050</classIRI>
<classLabel>negative regulation of histone exchange</classLabel>
<deletedAxiom>&apos;negative regulation of histone exchange&apos; SubClassOf &apos;negatively regulates&apos; some &apos;histone exchange&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone exchange&apos; SubClassOf &apos;negative regulation of chromatin organization&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone exchange&apos; SubClassOf &apos;regulation of histone exchange&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone exchange&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;histone exchange&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900051</classIRI>
<classLabel>positive regulation of histone exchange</classLabel>
<deletedAxiom>&apos;positive regulation of histone exchange&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;histone exchange&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone exchange&apos; SubClassOf &apos;positive regulation of chromatin organization&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone exchange&apos; SubClassOf &apos;positively regulates&apos; some &apos;histone exchange&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone exchange&apos; SubClassOf &apos;regulation of histone exchange&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_59082</classIRI>
<classLabel>N-{alpha-Glc-(1-3)-alpha-Glc-(1-3)-alpha-Man-(1-2)-alpha-Man-(1-2)-alpha-Man-(1-3)-[alpha-Man-(1-2)-alpha-Man-(1-3)-[alpha-Man-(1-2)-alpha-Man-(1-6)]-alpha-Man-(1-6)]-beta-Man-(1-4)-beta-GlcNAc-(1-4)-beta-GlcNAc}-L-Asn residue</classLabel>
<newAxiom>&apos;N-{alpha-Glc-(1-3)-alpha-Glc-(1-3)-alpha-Man-(1-2)-alpha-Man-(1-2)-alpha-Man-(1-3)-[alpha-Man-(1-2)-alpha-Man-(1-3)-[alpha-Man-(1-2)-alpha-Man-(1-6)]-alpha-Man-(1-6)]-beta-Man-(1-4)-beta-GlcNAc-(1-4)-beta-GlcNAc}-L-Asn residue&apos; SubClassOf http://purl.obolibrary.org/obo/CHEBI_192714</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_59080</classIRI>
<classLabel>N-{alpha-Glc-(1-3)-alpha-Man-(1-2)-alpha-Man-(1-2)-alpha-Man-(1-3)-[alpha-Man-(1-2)-alpha-Man-(1-3)-[alpha-Man-(1-2)-alpha-Man-(1-6)]-alpha-Man-(1-6)]-beta-Man-(1-4)-beta-GlcNAc-(1-4)-beta-GlcNAc}-L-Asn residue</classLabel>
<newAxiom>&apos;N-{alpha-Glc-(1-3)-alpha-Man-(1-2)-alpha-Man-(1-2)-alpha-Man-(1-3)-[alpha-Man-(1-2)-alpha-Man-(1-3)-[alpha-Man-(1-2)-alpha-Man-(1-6)]-alpha-Man-(1-6)]-beta-Man-(1-4)-beta-GlcNAc-(1-4)-beta-GlcNAc}-L-Asn residue&apos; SubClassOf http://purl.obolibrary.org/obo/CHEBI_192714</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004176</classIRI>
<classLabel>external genitalia</classLabel>
<deletedAxiom>&apos;external genitalia&apos; SubClassOf &apos;part of&apos; some &apos;genital system&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030337</classIRI>
<classLabel>DNA polymerase processivity factor activity</classLabel>
<deletedAxiom>&apos;DNA polymerase processivity factor activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;positively regulates&apos; some &apos;DNA polymerase activity&apos;)</deletedAxiom>
<newAxiom>&apos;DNA polymerase processivity factor activity&apos; EquivalentTo &apos;molecular function activator activity&apos; and (&apos;positively regulates&apos; some &apos;DNA polymerase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/FYPO_0003703</classIRI>
<classLabel>abnormal histone deacetylase activity</classLabel>
<newAxiom>&apos;abnormal histone deacetylase activity&apos; SubClassOf &apos;abnormal histone modification&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030295</classIRI>
<classLabel>protein kinase activator activity</classLabel>
<newAxiom>&apos;protein kinase activator activity&apos; EquivalentTo &apos;molecular function activator activity&apos; and (&apos;positively regulates&apos; some &apos;protein kinase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140677</classIRI>
<classLabel>molecular function activator activity</classLabel>
<newAxiom>&apos;molecular function activator activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;positively regulates&apos; some &apos;molecular_function&apos;)</newAxiom>
<newAxiom>&apos;molecular function activator activity&apos; SubClassOf &apos;positively regulates&apos; some &apos;molecular_function&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140656</classIRI>
<classLabel>endodeoxyribonuclease activator activity</classLabel>
<deletedAxiom>&apos;endodeoxyribonuclease activator activity&apos; EquivalentTo &apos;enzyme regulator activity&apos; and (&apos;positively regulates&apos; some &apos;endodeoxyribonuclease activity&apos;)</deletedAxiom>
<newAxiom>&apos;endodeoxyribonuclease activator activity&apos; EquivalentTo &apos;molecular function activator activity&apos; and (&apos;positively regulates&apos; some &apos;endodeoxyribonuclease activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043539</classIRI>
<classLabel>protein serine/threonine kinase activator activity</classLabel>
<newAxiom>&apos;protein serine/threonine kinase activator activity&apos; EquivalentTo &apos;molecular function activator activity&apos; and (&apos;positively regulates&apos; some &apos;protein serine/threonine kinase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140619</classIRI>
<classLabel>DNA strand exchange activator activity</classLabel>
<deletedAxiom>&apos;DNA strand exchange activator activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;positively regulates&apos; some &apos;DNA strand exchange activity&apos;)</deletedAxiom>
<newAxiom>&apos;DNA strand exchange activator activity&apos; EquivalentTo &apos;molecular function activator activity&apos; and (&apos;positively regulates&apos; some &apos;DNA strand exchange activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140608</classIRI>
<classLabel>cysteine-type endopeptidase activator activity</classLabel>
<deletedAxiom>&apos;cysteine-type endopeptidase activator activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;positively regulates&apos; some &apos;cysteine-type endopeptidase activity&apos;)</deletedAxiom>
<newAxiom>&apos;cysteine-type endopeptidase activator activity&apos; EquivalentTo &apos;molecular function activator activity&apos; and (&apos;positively regulates&apos; some &apos;cysteine-type endopeptidase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043494</classIRI>
<classLabel>CLRC complex</classLabel>
<deletedAxiom>&apos;CLRC complex&apos; SubClassOf &apos;Cul4B-RING E3 ubiquitin ligase complex&apos;</deletedAxiom>
<newAxiom>&apos;CLRC complex&apos; SubClassOf &apos;Cul4-RING E3 ubiquitin ligase complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043486</classIRI>
<classLabel>histone exchange</classLabel>
<deletedAxiom>&apos;histone exchange&apos; SubClassOf &apos;nucleosome organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030176</classIRI>
<classLabel>integral component of endoplasmic reticulum membrane</classLabel>
<deletedAxiom>&apos;integral component of endoplasmic reticulum membrane&apos; SubClassOf &apos;intrinsic component of endoplasmic reticulum membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;integral component of endoplasmic reticulum membrane&apos; EquivalentTo &apos;integral component of membrane&apos; and (&apos;part of&apos; some &apos;endoplasmic reticulum membrane&apos;)</deletedAxiom>
<deletedAxiom>&apos;integral component of endoplasmic reticulum membrane&apos; SubClassOf &apos;integral component of organelle membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_25940</classIRI>
<classLabel>peroxides</classLabel>
<newAxiom>&apos;peroxides&apos; SubClassOf &apos;has role&apos; some &apos;oxidising agent&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031465</classIRI>
<classLabel>Cul4B-RING E3 ubiquitin ligase complex</classLabel>
<deletedAxiom>&apos;Cul4B-RING E3 ubiquitin ligase complex&apos; SubClassOf &apos;Cul4-RING E3 ubiquitin ligase complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042054</classIRI>
<classLabel>histone methyltransferase activity</classLabel>
<deletedAxiom>&apos;histone methyltransferase activity&apos; SubClassOf &apos;part of&apos; some &apos;histone methylation&apos;</deletedAxiom>
<newAxiom>&apos;histone methyltransferase activity&apos; SubClassOf &apos;part of&apos; some &apos;histone modification&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002047</classIRI>
<classLabel>pontine raphe nucleus</classLabel>
<deletedAxiom>&apos;pontine raphe nucleus&apos; SubClassOf &apos;part of&apos; some &apos;raphe nuclei&apos;</deletedAxiom>
<newAxiom>&apos;pontine raphe nucleus&apos; SubClassOf &apos;part of&apos; some &apos;raphe nuclei&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005989</classIRI>
<classLabel>atrioventricular septum</classLabel>
<deletedAxiom>&apos;atrioventricular septum&apos; SubClassOf &apos;develops from&apos; some &apos;endocardial cushion&apos;</deletedAxiom>
<newAxiom>&apos;atrioventricular septum&apos; SubClassOf &apos;develops from&apos; some &apos;endocardial cushion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004666</classIRI>
<classLabel>interventricular septum membranous part</classLabel>
<deletedAxiom>&apos;interventricular septum membranous part&apos; SubClassOf &apos;develops from&apos; some &apos;cardiac neural crest&apos;</deletedAxiom>
<newAxiom>&apos;interventricular septum membranous part&apos; SubClassOf &apos;develops from&apos; some &apos;cardiac neural crest&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002012</classIRI>
<classLabel>pulmonary artery</classLabel>
<deletedAxiom>&apos;pulmonary artery&apos; SubClassOf &apos;develops from&apos; some &apos;truncus arteriosus&apos;</deletedAxiom>
<newAxiom>&apos;pulmonary artery&apos; SubClassOf &apos;develops from&apos; some &apos;truncus arteriosus&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004684</classIRI>
<classLabel>raphe nuclei</classLabel>
<deletedAxiom>&apos;raphe nuclei&apos; SubClassOf &apos;part of&apos; some &apos;reticular formation&apos;</deletedAxiom>
<deletedAxiom>&apos;raphe nuclei&apos; SubClassOf &apos;capable of&apos; some &apos;serotonin secretion&apos;</deletedAxiom>
<newAxiom>&apos;raphe nuclei&apos; SubClassOf &apos;part of&apos; some &apos;reticular formation&apos;</newAxiom>
<newAxiom>&apos;raphe nuclei&apos; SubClassOf &apos;capable of&apos; some &apos;serotonin secretion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031302</classIRI>
<classLabel>intrinsic component of endosome membrane</classLabel>
<deletedAxiom>&apos;intrinsic component of endosome membrane&apos; EquivalentTo &apos;intrinsic component of membrane&apos; and (&apos;part of&apos; some &apos;endosome membrane&apos;)</deletedAxiom>
<deletedAxiom>&apos;intrinsic component of endosome membrane&apos; SubClassOf &apos;intrinsic component of organelle membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;intrinsic component of endosome membrane&apos; SubClassOf &apos;part of&apos; some &apos;endosome membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031304</classIRI>
<classLabel>intrinsic component of mitochondrial inner membrane</classLabel>
<deletedAxiom>&apos;intrinsic component of mitochondrial inner membrane&apos; SubClassOf &apos;intrinsic component of mitochondrial membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;intrinsic component of mitochondrial inner membrane&apos; SubClassOf &apos;part of&apos; some &apos;mitochondrial inner membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;intrinsic component of mitochondrial inner membrane&apos; EquivalentTo &apos;intrinsic component of membrane&apos; and (&apos;part of&apos; some &apos;mitochondrial inner membrane&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031303</classIRI>
<classLabel>integral component of endosome membrane</classLabel>
<deletedAxiom>&apos;integral component of endosome membrane&apos; SubClassOf &apos;intrinsic component of endosome membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;integral component of endosome membrane&apos; SubClassOf &apos;integral component of organelle membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;integral component of endosome membrane&apos; EquivalentTo &apos;integral component of membrane&apos; and (&apos;part of&apos; some &apos;endosome membrane&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031305</classIRI>
<classLabel>integral component of mitochondrial inner membrane</classLabel>
<deletedAxiom>&apos;integral component of mitochondrial inner membrane&apos; SubClassOf &apos;intrinsic component of mitochondrial inner membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;integral component of mitochondrial inner membrane&apos; EquivalentTo &apos;integral component of membrane&apos; and (&apos;part of&apos; some &apos;mitochondrial inner membrane&apos;)</deletedAxiom>
<deletedAxiom>&apos;integral component of mitochondrial inner membrane&apos; SubClassOf &apos;integral component of mitochondrial membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005085</classIRI>
<classLabel>guanyl-nucleotide exchange factor activity</classLabel>
<newAxiom>&apos;guanyl-nucleotide exchange factor activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140678</newAxiom>
<newAxiom>&apos;guanyl-nucleotide exchange factor activity&apos; SubClassOf &apos;molecular function activator activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005096</classIRI>
<classLabel>GTPase activator activity</classLabel>
<deletedAxiom>&apos;GTPase activator activity&apos; EquivalentTo &apos;molecular function regulator activity&apos; and (&apos;positively regulates&apos; some &apos;GTPase activity&apos;)</deletedAxiom>
<newAxiom>&apos;GTPase activator activity&apos; EquivalentTo &apos;molecular function activator activity&apos; and (&apos;positively regulates&apos; some &apos;GTPase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032592</classIRI>
<classLabel>integral component of mitochondrial membrane</classLabel>
<deletedAxiom>&apos;integral component of mitochondrial membrane&apos; EquivalentTo &apos;integral component of membrane&apos; and (&apos;part of&apos; some &apos;mitochondrial membrane&apos;)</deletedAxiom>
<deletedAxiom>&apos;integral component of mitochondrial membrane&apos; SubClassOf &apos;intrinsic component of mitochondrial membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;integral component of mitochondrial membrane&apos; SubClassOf &apos;integral component of organelle membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0039222</classIRI>
<classLabel>cystic artery</classLabel>
<deletedAxiom>&apos;cystic artery&apos; SubClassOf &apos;part of&apos; some &apos;right hepatic artery&apos;</deletedAxiom>
<newAxiom>&apos;cystic artery&apos; SubClassOf &apos;part of&apos; some &apos;right hepatic artery&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045815</classIRI>
<classLabel>epigenetic maintenance of chromatin in transcription-competent conformation</classLabel>
<deletedAxiom>&apos;epigenetic maintenance of chromatin in transcription-competent conformation&apos; EquivalentTo &apos;epigenetic regulation of gene expression&apos; and (&apos;positively regulates&apos; some &apos;gene expression&apos;)</deletedAxiom>
<deletedAxiom>&apos;epigenetic maintenance of chromatin in transcription-competent conformation&apos; SubClassOf &apos;positive regulation of gene expression&apos;</deletedAxiom>
<deletedAxiom>&apos;epigenetic maintenance of chromatin in transcription-competent conformation&apos; SubClassOf &apos;chromatin remodeling&apos;</deletedAxiom>
<deletedAxiom>&apos;epigenetic maintenance of chromatin in transcription-competent conformation&apos; SubClassOf &apos;epigenetic regulation of gene expression&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033857</classIRI>
<classLabel>diphosphoinositol-pentakisphosphate kinase activity</classLabel>
<deletedAxiom>&apos;diphosphoinositol-pentakisphosphate kinase activity&apos; SubClassOf &apos;phosphotransferase activity, phosphate group as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031227</classIRI>
<classLabel>intrinsic component of endoplasmic reticulum membrane</classLabel>
<deletedAxiom>&apos;intrinsic component of endoplasmic reticulum membrane&apos; SubClassOf &apos;part of&apos; some &apos;endoplasmic reticulum membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;intrinsic component of endoplasmic reticulum membrane&apos; EquivalentTo &apos;intrinsic component of membrane&apos; and (&apos;part of&apos; some &apos;endoplasmic reticulum membrane&apos;)</deletedAxiom>
<deletedAxiom>&apos;intrinsic component of endoplasmic reticulum membrane&apos; SubClassOf &apos;intrinsic component of organelle membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031229</classIRI>
<classLabel>intrinsic component of nuclear inner membrane</classLabel>
<deletedAxiom>&apos;intrinsic component of nuclear inner membrane&apos; SubClassOf &apos;intrinsic component of organelle membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;intrinsic component of nuclear inner membrane&apos; EquivalentTo &apos;intrinsic component of membrane&apos; and (&apos;part of&apos; some &apos;nuclear inner membrane&apos;)</deletedAxiom>
<deletedAxiom>&apos;intrinsic component of nuclear inner membrane&apos; SubClassOf &apos;part of&apos; some &apos;nuclear inner membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031233</classIRI>
<classLabel>intrinsic component of external side of plasma membrane</classLabel>
<deletedAxiom>&apos;intrinsic component of external side of plasma membrane&apos; EquivalentTo &apos;intrinsic component of plasma membrane&apos; and (&apos;part of&apos; some &apos;external side of plasma membrane&apos;)</deletedAxiom>
<deletedAxiom>&apos;intrinsic component of external side of plasma membrane&apos; SubClassOf &apos;part of&apos; some &apos;external side of plasma membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;intrinsic component of external side of plasma membrane&apos; SubClassOf &apos;intrinsic component of plasma membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/FYPO_0004783</classIRI>
<classLabel>abnormal histone methyltransferase activity</classLabel>
<deletedAxiom>&apos;abnormal histone methyltransferase activity&apos; SubClassOf &apos;abnormal histone methylation&apos;</deletedAxiom>
<newAxiom>&apos;abnormal histone methyltransferase activity&apos; SubClassOf &apos;abnormal histone modification&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004456</classIRI>
<classLabel>entire sense organ system</classLabel>
<deletedAxiom>&apos;renal system&apos; DisjointWith &apos;entire sense organ system&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003133</classIRI>
<classLabel>reproductive organ</classLabel>
<deletedAxiom>&apos;reproductive organ&apos; EquivalentTo &apos;organ&apos; and (&apos;capable of&apos; some &apos;reproduction&apos;)</deletedAxiom>
<deletedAxiom>&apos;reproductive organ&apos; SubClassOf &apos;capable of&apos; some &apos;reproduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_3011048</classIRI>
<classLabel>genital system</classLabel>
<deletedAxiom>&apos;genital system&apos; SubClassOf &apos;anatomical system&apos;</deletedAxiom>
<deletedAxiom>&apos;genital system&apos; SubClassOf &apos;part of&apos; some &apos;genitourinary system&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032452</classIRI>
<classLabel>histone demethylase activity</classLabel>
<newAxiom>&apos;histone demethylase activity&apos; SubClassOf &apos;part of&apos; some &apos;histone modification&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031033</classIRI>
<classLabel>myosin filament organization</classLabel>
<deletedAxiom>&apos;myosin filament organization&apos; SubClassOf &apos;actin cytoskeleton organization&apos;</deletedAxiom>
<deletedAxiom>&apos;myosin filament organization&apos; SubClassOf &apos;supramolecular fiber organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003075</classIRI>
<classLabel>neural plate</classLabel>
<deletedAxiom>&apos;neural plate&apos; SubClassOf &apos;developmentally induced by&apos; some &apos;notochord&apos;</deletedAxiom>
<newAxiom>&apos;neural plate&apos; SubClassOf &apos;developmentally induced by&apos; some &apos;notochord&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008641</classIRI>
<classLabel>ubiquitin-like modifier activating enzyme activity</classLabel>
<newAxiom>&apos;ubiquitin-like modifier activating enzyme activity&apos; SubClassOf &apos;ATP-dependent activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008654</classIRI>
<classLabel>phospholipid biosynthetic process</classLabel>
<deletedAxiom>&apos;phospholipid biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010853</classIRI>
<classLabel>cyclase activator activity</classLabel>
<newAxiom>'cyclase activator activity' SubClassOf 'cyclase regulator activity'</newAxiom>
<newAxiom>'cyclase activator activity' SubClassOf 'positively regulates' some 'cyclase activity'</newAxiom>
<newAxiom>'cyclase activator activity' EquivalentTo 'molecular function activator activity' and ('positively regulates' some 'cyclase activity')</newAxiom>
<newAxiom>'cyclase activator activity' SubClassOf 'enzyme activator activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010855</classIRI>
<classLabel>adenylate cyclase inhibitor activity</classLabel>
<newAxiom>'adenylate cyclase inhibitor activity' SubClassOf 'cyclase inhibitor activity'</newAxiom>
<newAxiom>'adenylate cyclase inhibitor activity' SubClassOf 'adenylate cyclase regulator activity'</newAxiom>
<newAxiom>'adenylate cyclase inhibitor activity' SubClassOf 'negatively regulates' some 'adenylate cyclase activity'</newAxiom>
<newAxiom>'adenylate cyclase inhibitor activity' EquivalentTo 'molecular function inhibitor activity' and ('negatively regulates' some 'adenylate cyclase activity')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033526</classIRI>
<classLabel>tetrapyrrole biosynthetic process from glutamate</classLabel>
<newAxiom>'tetrapyrrole biosynthetic process from glutamate' SubClassOf 'tetrapyrrole biosynthetic process'</newAxiom>
<newAxiom>'tetrapyrrole biosynthetic process from glutamate' SubClassOf 'glutamate metabolic process'</newAxiom>
<newAxiom>'tetrapyrrole biosynthetic process from glutamate' SubClassOf 'has primary input' some 'glutamate(1-)'</newAxiom>
<newAxiom>'tetrapyrrole biosynthetic process from glutamate' EquivalentTo 'biosynthetic process' and ('has primary output' some 'tetrapyrrole') and ('has primary input' some 'glutamate(1-)')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010698</classIRI>
<classLabel>acetyltransferase activator activity</classLabel>
<newAxiom>'acetyltransferase activator activity' SubClassOf 'enzyme activator activity'</newAxiom>
<newAxiom>'acetyltransferase activator activity' SubClassOf 'positively regulates' some 'acetyltransferase activity'</newAxiom>
<newAxiom>'acetyltransferase activator activity' EquivalentTo 'molecular function activator activity' and ('positively regulates' some 'acetyltransferase activity')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008200</classIRI>
<classLabel>ion channel inhibitor activity</classLabel>
<newAxiom>'ion channel inhibitor activity' SubClassOf 'channel inhibitor activity'</newAxiom>
<newAxiom>'ion channel inhibitor activity' EquivalentTo 'molecular function inhibitor activity' and ('negatively regulates' some 'ion channel activity')</newAxiom>
<newAxiom>'ion channel inhibitor activity' SubClassOf 'has_part' some 'transmembrane transporter binding'</newAxiom>
<newAxiom>'ion channel inhibitor activity' SubClassOf 'negatively regulates' some 'ion channel activity'</newAxiom>
<newAxiom>'ion channel inhibitor activity' SubClassOf 'ion channel regulator activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072587</classIRI>
<classLabel>DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity</classLabel>
<newAxiom>'DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity' SubClassOf 'DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity'</newAxiom>
<newAxiom>'DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity' SubClassOf 'positively regulates' some 'DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity'</newAxiom>
<newAxiom>'DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity' SubClassOf 'enzyme activator activity'</newAxiom>
<newAxiom>'DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity' EquivalentTo 'molecular function activator activity' and ('positively regulates' some 'DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072586</classIRI>
<classLabel>DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity</classLabel>
<newAxiom>'DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity' SubClassOf 'enzyme regulator activity'</newAxiom>
<newAxiom>'DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity' SubClassOf 'regulates' some 'DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity'</newAxiom>
<newAxiom>'DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity' EquivalentTo 'molecular function regulator activity' and ('regulates' some 'DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_473992</classIRI>
<classLabel>nystatin A1</classLabel>
<newAxiom>'nystatin A1' SubClassOf 'nystatins'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009084</classIRI>
<classLabel>glutamine family amino acid biosynthetic process</classLabel>
<newAxiom>'glutamine family amino acid biosynthetic process' SubClassOf 'has primary output' some 'glutamine family amino acid'</newAxiom>
<newAxiom>'glutamine family amino acid biosynthetic process' SubClassOf 'glutamine family amino acid metabolic process'</newAxiom>
<newAxiom>'glutamine family amino acid biosynthetic process' EquivalentTo 'biosynthetic process' and ('has primary output' some 'glutamine family amino acid')</newAxiom>
<newAxiom>'glutamine family amino acid biosynthetic process' SubClassOf 'alpha-amino acid biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000211</classIRI>
<classLabel>regulation of glutamate metabolic process</classLabel>
<newAxiom>'regulation of glutamate metabolic process' SubClassOf 'regulation of glutamine family amino acid metabolic process'</newAxiom>
<newAxiom>'regulation of glutamate metabolic process' SubClassOf 'regulates' some 'glutamate metabolic process'</newAxiom>
<newAxiom>'regulation of glutamate metabolic process' EquivalentTo 'biological regulation' and ('regulates' some 'glutamate metabolic process')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000212</classIRI>
<classLabel>negative regulation of glutamate metabolic process</classLabel>
<newAxiom>'negative regulation of glutamate metabolic process' SubClassOf 'negative regulation of cellular amino acid metabolic process'</newAxiom>
<newAxiom>'negative regulation of glutamate metabolic process' SubClassOf 'regulation of glutamate metabolic process'</newAxiom>
<newAxiom>'negative regulation of glutamate metabolic process' EquivalentTo 'biological regulation' and ('negatively regulates' some 'glutamate metabolic process')</newAxiom>
<newAxiom>'negative regulation of glutamate metabolic process' SubClassOf 'negatively regulates' some 'glutamate metabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000213</classIRI>
<classLabel>positive regulation of glutamate metabolic process</classLabel>
<newAxiom>'positive regulation of glutamate metabolic process' SubClassOf 'positively regulates' some 'glutamate metabolic process'</newAxiom>
<newAxiom>'positive regulation of glutamate metabolic process' EquivalentTo 'biological regulation' and ('positively regulates' some 'glutamate metabolic process')</newAxiom>
<newAxiom>'positive regulation of glutamate metabolic process' SubClassOf 'positive regulation of cellular amino acid metabolic process'</newAxiom>
<newAxiom>'positive regulation of glutamate metabolic process' SubClassOf 'regulation of glutamate metabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_192979</classIRI>
<classLabel>nystatin A2</classLabel>
<newAxiom>'nystatin A2' SubClassOf 'nystatins'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/FYPO_0008013</classIRI>
<classLabel>normal inositol hexakisphosphate kinase activity</classLabel>
<newAxiom>'normal inositol hexakisphosphate kinase activity' EquivalentTo 'has_part' some 
('quality' and ('characteristic of' some 'inositol hexakisphosphate kinase activity') and ('has modifier' some 'normal'))</newAxiom>
<newAxiom>'normal inositol hexakisphosphate kinase activity' SubClassOf 'normal catalytic activity'</newAxiom>
<newAxiom>'normal inositol hexakisphosphate kinase activity' SubClassOf 'has_part' some 
('quality' and ('characteristic of' some 'inositol hexakisphosphate kinase activity') and ('has modifier' some 'normal'))</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/FYPO_0008014</classIRI>
<classLabel>decreased protein localization to CENP-A containing chromatin during mitosis</classLabel>
<newAxiom>'decreased protein localization to CENP-A containing chromatin during mitosis' SubClassOf 'decreased protein localization to CENP-A containing chromatin'</newAxiom>
<newAxiom>'decreased protein localization to CENP-A containing chromatin during mitosis' EquivalentTo 'has_part' some 
('decreased occurrence' and ('characteristic of' some 
('protein localization to CENP-A containing chromatin' and ('happens during' some 'mitotic M phase'))))</newAxiom>
<newAxiom>'decreased protein localization to CENP-A containing chromatin during mitosis' SubClassOf 'has_part' some 
('decreased occurrence' and ('characteristic of' some 
('protein localization to CENP-A containing chromatin' and ('happens during' some 'mitotic M phase'))))</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/FYPO_0008026</classIRI>
<classLabel>increased protein localization to CENP-A containing chromatin during mitosis</classLabel>
<newAxiom>'increased protein localization to CENP-A containing chromatin during mitosis' EquivalentTo 'has_part' some 
('increased occurrence' and ('characteristic of' some 
('protein localization to CENP-A containing chromatin' and ('happens during' some 'mitotic M phase'))))</newAxiom>
<newAxiom>'increased protein localization to CENP-A containing chromatin during mitosis' SubClassOf 'has_part' some 
('increased occurrence' and ('characteristic of' some 
('protein localization to CENP-A containing chromatin' and ('happens during' some 'mitotic M phase'))))</newAxiom>
<newAxiom>'increased protein localization to CENP-A containing chromatin during mitosis' SubClassOf 'increased protein localization to CENP-A containing chromatin'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/FYPO_0008019</classIRI>
<classLabel>normal growth on arginine nitrogen source</classLabel>
<newAxiom>'normal growth on arginine nitrogen source' SubClassOf 'normal vegetative cell population growth'</newAxiom>
<newAxiom>'normal growth on arginine nitrogen source' SubClassOf 'has_part' some 
('normal cell population growth' and ('happens_during' some 'single-celled organism vegetative growth phase') and ('characteristic of' some 'culture medium') and ('towards' some 'arginine') and ('has modifier' some 'present'))</newAxiom>
<newAxiom>'normal growth on arginine nitrogen source' EquivalentTo 'has_part' some 
('normal cell population growth' and ('happens_during' some 'single-celled organism vegetative growth phase') and ('characteristic of' some 'culture medium') and ('towards' some 'arginine') and ('has modifier' some 'present'))</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/FYPO_0008015</classIRI>
<classLabel>decreased glucose import</classLabel>
<newAxiom>'decreased glucose import' EquivalentTo 'has_part' some 
('decreased occurrence' and ('characteristic of' some 
('glucose import across plasma membrane' and ('happens during' some 'single-celled organism vegetative growth phase'))))</newAxiom>
<newAxiom>'decreased glucose import' SubClassOf 'has_part' some 
('decreased occurrence' and ('characteristic of' some 
('glucose import across plasma membrane' and ('happens during' some 'single-celled organism vegetative growth phase'))))</newAxiom>
<newAxiom>'decreased glucose import' SubClassOf 'abnormal glucose import'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/FYPO_0008016</classIRI>
<classLabel>decreased phenylalanine import during vegetative growth</classLabel>
<newAxiom>'decreased phenylalanine import during vegetative growth' SubClassOf 'decreased amino acid import during vegetative growth'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/FYPO_0008017</classIRI>
<classLabel>normal growth on glutamate nitrogen source</classLabel>
<newAxiom>'normal growth on glutamate nitrogen source' SubClassOf 'normal vegetative cell population growth'</newAxiom>
<newAxiom>'normal growth on glutamate nitrogen source' SubClassOf 'has_part' some 
('normal cell population growth' and ('happens_during' some 'single-celled organism vegetative growth phase') and ('characteristic of' some 'culture medium') and ('towards' some 'glutamate(1-)') and ('has modifier' some 'present'))</newAxiom>
<newAxiom>'normal growth on glutamate nitrogen source' EquivalentTo 'has_part' some 
('normal cell population growth' and ('happens_during' some 'single-celled organism vegetative growth phase') and ('characteristic of' some 'culture medium') and ('towards' some 'glutamate(1-)') and ('has modifier' some 'present'))</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/FYPO_0008018</classIRI>
<classLabel>normal growth on glutamine nitrogen source</classLabel>
<newAxiom>'normal growth on glutamine nitrogen source' SubClassOf 'normal vegetative cell population growth'</newAxiom>
<newAxiom>'normal growth on glutamine nitrogen source' EquivalentTo 'has_part' some 
('normal cell population growth' and ('happens_during' some 'single-celled organism vegetative growth phase') and ('characteristic of' some 'culture medium') and ('towards' some 'glutamine') and ('has modifier' some 'present'))</newAxiom>
<newAxiom>'normal growth on glutamine nitrogen source' SubClassOf 'has_part' some 
('normal cell population growth' and ('happens_during' some 'single-celled organism vegetative growth phase') and ('characteristic of' some 'culture medium') and ('towards' some 'glutamine') and ('has modifier' some 'present'))</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/FYPO_0008022</classIRI>
<classLabel>abolished cell population growth on alanine nitrogen source</classLabel>
<newAxiom>'abolished cell population growth on alanine nitrogen source' EquivalentTo 'has_part' some 
('abolished vegetative cell population growth' and ('characteristic of' some 'culture medium') and ('towards' some 'alanine') and ('has modifier' some 'present'))</newAxiom>
<newAxiom>'abolished cell population growth on alanine nitrogen source' SubClassOf 'has_part' some 
('abolished vegetative cell population growth' and ('characteristic of' some 'culture medium') and ('towards' some 'alanine') and ('has modifier' some 'present'))</newAxiom>
<newAxiom>'abolished cell population growth on alanine nitrogen source' SubClassOf 'abolished vegetative cell population growth'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/FYPO_0008023</classIRI>
<classLabel>abolished cell population growth on leucine nitrogen source</classLabel>
<newAxiom>'abolished cell population growth on leucine nitrogen source' SubClassOf 'has_part' some 
('abolished vegetative cell population growth' and ('characteristic of' some 'culture medium') and ('towards' some 'leucine') and ('has modifier' some 'present'))</newAxiom>
<newAxiom>'abolished cell population growth on leucine nitrogen source' EquivalentTo 'has_part' some 
('abolished vegetative cell population growth' and ('characteristic of' some 'culture medium') and ('towards' some 'leucine') and ('has modifier' some 'present'))</newAxiom>
<newAxiom>'abolished cell population growth on leucine nitrogen source' SubClassOf 'abolished vegetative cell population growth'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/FYPO_0008025</classIRI>
<classLabel>normal protein localization to CENP-A containing chromatin during mitosis</classLabel>
<newAxiom>'normal protein localization to CENP-A containing chromatin during mitosis' EquivalentTo 'has_part' some 
('quality' and ('happens_during' some 'mitotic M phase') and ('characteristic of' some 'protein localization to CENP-A containing chromatin') and ('has modifier' some 'normal'))</newAxiom>
<newAxiom>'normal protein localization to CENP-A containing chromatin during mitosis' SubClassOf 'normal protein localization to CENP-A containing chromatin'</newAxiom>
<newAxiom>'normal protein localization to CENP-A containing chromatin during mitosis' SubClassOf 'has_part' some 
('quality' and ('happens_during' some 'mitotic M phase') and ('characteristic of' some 'protein localization to CENP-A containing chromatin') and ('has modifier' some 'normal'))</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/FYPO_0008020</classIRI>
<classLabel>decreased cell population growth on leucine nitrogen source</classLabel>
<newAxiom>'decreased cell population growth on leucine nitrogen source' EquivalentTo 'has_part' some 
('decreased cell population growth' and ('happens_during' some 'single-celled organism vegetative growth phase') and ('characteristic of' some 'culture medium') and ('towards' some 'leucine') and ('has modifier' some 'present'))</newAxiom>
<newAxiom>'decreased cell population growth on leucine nitrogen source' SubClassOf 'decreased vegetative cell population growth'</newAxiom>
<newAxiom>'decreased cell population growth on leucine nitrogen source' SubClassOf 'has_part' some 
('decreased cell population growth' and ('happens_during' some 'single-celled organism vegetative growth phase') and ('characteristic of' some 'culture medium') and ('towards' some 'leucine') and ('has modifier' some 'present'))</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/FYPO_0008021</classIRI>
<classLabel>decreased cell population growth on alanine nitrogen source</classLabel>
<newAxiom>'decreased cell population growth on alanine nitrogen source' EquivalentTo 'has_part' some 
('decreased cell population growth' and ('happens_during' some 'single-celled organism vegetative growth phase') and ('characteristic of' some 'culture medium') and ('towards' some 'alanine') and ('has modifier' some 'present'))</newAxiom>
<newAxiom>'decreased cell population growth on alanine nitrogen source' SubClassOf 'has_part' some 
('decreased cell population growth' and ('happens_during' some 'single-celled organism vegetative growth phase') and ('characteristic of' some 'culture medium') and ('towards' some 'alanine') and ('has modifier' some 'present'))</newAxiom>
<newAxiom>'decreased cell population growth on alanine nitrogen source' SubClassOf 'decreased vegetative cell population growth'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097027</classIRI>
<classLabel>ubiquitin-protein transferase activator activity</classLabel>
<newAxiom>'ubiquitin-protein transferase activator activity' EquivalentTo 'molecular function activator activity' and ('positively regulates' some 'ubiquitin-protein transferase activity')</newAxiom>
<newAxiom>'ubiquitin-protein transferase activator activity' SubClassOf 'ubiquitin-protein transferase regulator activity'</newAxiom>
<newAxiom>'ubiquitin-protein transferase activator activity' SubClassOf 'enzyme activator activity'</newAxiom>
<newAxiom>'ubiquitin-protein transferase activator activity' SubClassOf 'positively regulates' some 'ubiquitin-protein transferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_192714</classIRI>
<classLabel>an N(4)-(oligosaccharide-(1-3)-[oligosaccharide-(1-6)]-beta-D-Man-(1-4)-beta-D-GlcNAc-(1-4)-alpha-D-GlcNAc)-L-asparaginyl residue</classLabel>
<newAxiom>'an N(4)-(oligosaccharide-(1-3)-[oligosaccharide-(1-6)]-beta-D-Man-(1-4)-beta-D-GlcNAc-(1-4)-alpha-D-GlcNAc)-L-asparaginyl residue' SubClassOf 'N(4)-(oligosaccharide-(1-4)-N-acetyl-beta-D-glucosaminyl-(1-4)-N-acetyl-beta-D-glucosaminyl)-L-asparagine residue'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_32664</classIRI>
<classLabel>asparagine residue</classLabel>
<newAxiom>'asparagine residue' SubClassOf 'is substituent group from' some 'asparagine'</newAxiom>
<newAxiom>'asparagine residue' SubClassOf 'alpha-amino-acid residue'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990521</classIRI>
<classLabel>m7G(5')pppN diphosphatase activator activity</classLabel>
<newAxiom>'m7G(5')pppN diphosphatase activator activity' SubClassOf 'enzyme activator activity'</newAxiom>
<newAxiom>'m7G(5')pppN diphosphatase activator activity' EquivalentTo 'molecular function activator activity' and ('positively regulates' some 'm7G(5')pppN diphosphatase activity')</newAxiom>
<newAxiom>'m7G(5')pppN diphosphatase activator activity' SubClassOf 'positively regulates' some 'm7G(5')pppN diphosphatase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990609</classIRI>
<classLabel>glutamate-cysteine ligase regulator activity</classLabel>
<newAxiom>'glutamate-cysteine ligase regulator activity' SubClassOf 'ligase regulator activity'</newAxiom>
<newAxiom>'glutamate-cysteine ligase regulator activity' SubClassOf 'regulates' some 'glutamate-cysteine ligase activity'</newAxiom>
<newAxiom>'glutamate-cysteine ligase regulator activity' EquivalentTo 'molecular function regulator activity' and ('regulates' some 'glutamate-cysteine ligase activity')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_132529</classIRI>
<classLabel>N(4)-(oligosaccharide-(1-4)-N-acetyl-beta-D-glucosaminyl-(1-4)-N-acetyl-beta-D-glucosaminyl)-L-asparagine residue</classLabel>
<newAxiom>'N(4)-(oligosaccharide-(1-4)-N-acetyl-beta-D-glucosaminyl-(1-4)-N-acetyl-beta-D-glucosaminyl)-L-asparagine residue' SubClassOf 'L-alpha-amino acid residue'</newAxiom>
<newAxiom>'N(4)-(oligosaccharide-(1-4)-N-acetyl-beta-D-glucosaminyl-(1-4)-N-acetyl-beta-D-glucosaminyl)-L-asparagine residue' SubClassOf 'has functional parent' some 'asparagine residue'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990749</classIRI>
<classLabel>polynucleotide adenylyltransferase activator activity</classLabel>
<newAxiom>'polynucleotide adenylyltransferase activator activity' EquivalentTo 'molecular function activator activity' and ('positively regulates' some 'polynucleotide adenylyltransferase activity')</newAxiom>
<newAxiom>'polynucleotide adenylyltransferase activator activity' SubClassOf 'positively regulates' some 'polynucleotide adenylyltransferase activity'</newAxiom>
<newAxiom>'polynucleotide adenylyltransferase activator activity' SubClassOf 'enzyme activator activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015451</classIRI>
<classLabel>decarboxylation-driven active transmembrane transporter activity</classLabel>
<newAxiom>'decarboxylation-driven active transmembrane transporter activity' SubClassOf 'has_part' some 'carboxy-lyase activity'</newAxiom>
<newAxiom>'decarboxylation-driven active transmembrane transporter activity' EquivalentTo 'primary active transmembrane transporter activity' and ('has_part' some 'carboxy-lyase activity')</newAxiom>
<newAxiom>'decarboxylation-driven active transmembrane transporter activity' SubClassOf 'primary active transmembrane transporter activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015452</classIRI>
<classLabel>methyl transfer-driven active transmembrane transporter activity</classLabel>
<newAxiom>'methyl transfer-driven active transmembrane transporter activity' SubClassOf 'primary active transmembrane transporter activity'</newAxiom>
<newAxiom>'methyl transfer-driven active transmembrane transporter activity' EquivalentTo 'primary active transmembrane transporter activity' and ('has_part' some 'methyltransferase activity')</newAxiom>
<newAxiom>'methyl transfer-driven active transmembrane transporter activity' SubClassOf 'has_part' some 'methyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014049</classIRI>
<classLabel>positive regulation of glutamate secretion</classLabel>
<newAxiom>'positive regulation of glutamate secretion' SubClassOf 'positive regulation of secretion by cell'</newAxiom>
<newAxiom>'positive regulation of glutamate secretion' SubClassOf 'regulation of glutamate secretion'</newAxiom>
<newAxiom>'positive regulation of glutamate secretion' EquivalentTo 'biological regulation' and ('positively regulates' some 'glutamate secretion')</newAxiom>
<newAxiom>'positive regulation of glutamate secretion' SubClassOf 'positively regulates' some 'glutamate secretion'</newAxiom>
<newAxiom>'positive regulation of glutamate secretion' SubClassOf 'positive regulation of anion transport'</newAxiom>
<newAxiom>'positive regulation of glutamate secretion' SubClassOf 'positive regulation of amino acid transport'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014047</classIRI>
<classLabel>glutamate secretion</classLabel>
<newAxiom>'glutamate secretion' SubClassOf 'carboxylic acid transport'</newAxiom>
<newAxiom>'glutamate secretion' SubClassOf 'secretion by cell'</newAxiom>
<newAxiom>'glutamate secretion' EquivalentTo 'secretion' and ('has primary input' some 'glutamate(1-)')</newAxiom>
<newAxiom>'glutamate secretion' SubClassOf 'has primary input' some 'glutamate(1-)'</newAxiom>
<newAxiom>'glutamate secretion' SubClassOf 'acidic amino acid transport'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014048</classIRI>
<classLabel>regulation of glutamate secretion</classLabel>
<newAxiom>'regulation of glutamate secretion' SubClassOf 'regulation of secretion by cell'</newAxiom>
<newAxiom>'regulation of glutamate secretion' SubClassOf 'regulates' some 'glutamate secretion'</newAxiom>
<newAxiom>'regulation of glutamate secretion' EquivalentTo 'biological regulation' and ('regulates' some 'glutamate secretion')</newAxiom>
<newAxiom>'regulation of glutamate secretion' SubClassOf 'regulation of anion transport'</newAxiom>
<newAxiom>'regulation of glutamate secretion' SubClassOf 'regulation of amino acid transport'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014050</classIRI>
<classLabel>negative regulation of glutamate secretion</classLabel>
<newAxiom>'negative regulation of glutamate secretion' SubClassOf 'negative regulation of anion transport'</newAxiom>
<newAxiom>'negative regulation of glutamate secretion' SubClassOf 'negative regulation of secretion by cell'</newAxiom>
<newAxiom>'negative regulation of glutamate secretion' EquivalentTo 'biological regulation' and ('negatively regulates' some 'glutamate secretion')</newAxiom>
<newAxiom>'negative regulation of glutamate secretion' SubClassOf 'regulation of glutamate secretion'</newAxiom>
<newAxiom>'negative regulation of glutamate secretion' SubClassOf 'negative regulation of amino acid transport'</newAxiom>
<newAxiom>'negative regulation of glutamate secretion' SubClassOf 'negatively regulates' some 'glutamate secretion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016595</classIRI>
<classLabel>glutamate binding</classLabel>
<newAxiom>'glutamate binding' SubClassOf 'carboxylic acid binding'</newAxiom>
<newAxiom>'glutamate binding' SubClassOf 'has input' some 'glutamate(1-)'</newAxiom>
<newAxiom>'glutamate binding' EquivalentTo 'binding' and ('has input' some 'glutamate(1-)')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090461</classIRI>
<classLabel>glutamate homeostasis</classLabel>
<newAxiom>'glutamate homeostasis' SubClassOf 'amino acid homeostasis'</newAxiom>
<newAxiom>'glutamate homeostasis' SubClassOf 'anion homeostasis'</newAxiom>
<newAxiom>'glutamate homeostasis' SubClassOf 'regulates levels of' some 'glutamate(1-)'</newAxiom>
<newAxiom>'glutamate homeostasis' EquivalentTo 'chemical homeostasis' and ('regulates levels of' some 'glutamate(1-)')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_31927</classIRI>
<classLabel>nystatin A3</classLabel>
<newAxiom>'nystatin A3' SubClassOf 'nystatins'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016248</classIRI>
<classLabel>channel inhibitor activity</classLabel>
<newAxiom>'channel inhibitor activity' SubClassOf 'channel regulator activity'</newAxiom>
<newAxiom>'channel inhibitor activity' EquivalentTo 'molecular function inhibitor activity' and ('negatively regulates' some 'channel activity')</newAxiom>
<newAxiom>'channel inhibitor activity' SubClassOf 'molecular function inhibitor activity'</newAxiom>
<newAxiom>'channel inhibitor activity' SubClassOf 'negatively regulates' some 'channel activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901410</classIRI>
<classLabel>regulation of tetrapyrrole biosynthetic process from glutamate</classLabel>
<newAxiom>'regulation of tetrapyrrole biosynthetic process from glutamate' SubClassOf 'regulates' some 'tetrapyrrole biosynthetic process from glutamate'</newAxiom>
<newAxiom>'regulation of tetrapyrrole biosynthetic process from glutamate' SubClassOf 'regulation of glutamate metabolic process'</newAxiom>
<newAxiom>'regulation of tetrapyrrole biosynthetic process from glutamate' SubClassOf 'regulation of tetrapyrrole biosynthetic process'</newAxiom>
<newAxiom>'regulation of tetrapyrrole biosynthetic process from glutamate' EquivalentTo 'biological regulation' and ('regulates' some 'tetrapyrrole biosynthetic process from glutamate')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901411</classIRI>
<classLabel>negative regulation of tetrapyrrole biosynthetic process from glutamate</classLabel>
<newAxiom>'negative regulation of tetrapyrrole biosynthetic process from glutamate' SubClassOf 'regulation of tetrapyrrole biosynthetic process from glutamate'</newAxiom>
<newAxiom>'negative regulation of tetrapyrrole biosynthetic process from glutamate' SubClassOf 'negative regulation of glutamate metabolic process'</newAxiom>
<newAxiom>'negative regulation of tetrapyrrole biosynthetic process from glutamate' EquivalentTo 'biological regulation' and ('negatively regulates' some 'tetrapyrrole biosynthetic process from glutamate')</newAxiom>
<newAxiom>'negative regulation of tetrapyrrole biosynthetic process from glutamate' SubClassOf 'negative regulation of tetrapyrrole biosynthetic process'</newAxiom>
<newAxiom>'negative regulation of tetrapyrrole biosynthetic process from glutamate' SubClassOf 'negatively regulates' some 'tetrapyrrole biosynthetic process from glutamate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901412</classIRI>
<classLabel>positive regulation of tetrapyrrole biosynthetic process from glutamate</classLabel>
<newAxiom>'positive regulation of tetrapyrrole biosynthetic process from glutamate' SubClassOf 'regulation of tetrapyrrole biosynthetic process from glutamate'</newAxiom>
<newAxiom>'positive regulation of tetrapyrrole biosynthetic process from glutamate' EquivalentTo 'biological regulation' and ('positively regulates' some 'tetrapyrrole biosynthetic process from glutamate')</newAxiom>
<newAxiom>'positive regulation of tetrapyrrole biosynthetic process from glutamate' SubClassOf 'positively regulates' some 'tetrapyrrole biosynthetic process from glutamate'</newAxiom>
<newAxiom>'positive regulation of tetrapyrrole biosynthetic process from glutamate' SubClassOf 'positive regulation of glutamate metabolic process'</newAxiom>
<newAxiom>'positive regulation of tetrapyrrole biosynthetic process from glutamate' SubClassOf 'positive regulation of tetrapyrrole biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006537</classIRI>
<classLabel>glutamate biosynthetic process</classLabel>
<newAxiom>'glutamate biosynthetic process' SubClassOf 'has primary output' some 'glutamate(1-)'</newAxiom>
<newAxiom>'glutamate biosynthetic process' SubClassOf 'glutamate metabolic process'</newAxiom>
<newAxiom>'glutamate biosynthetic process' SubClassOf 'glutamine family amino acid biosynthetic process'</newAxiom>
<newAxiom>'glutamate biosynthetic process' EquivalentTo 'biosynthetic process' and ('has primary output' some 'glutamate(1-)')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006536</classIRI>
<classLabel>glutamate metabolic process</classLabel>
<newAxiom>'glutamate metabolic process' SubClassOf 'has primary input or output' some 'glutamate(1-)'</newAxiom>
<newAxiom>'glutamate metabolic process' EquivalentTo 'metabolic process' and ('has primary input or output' some 'glutamate(1-)')</newAxiom>
<newAxiom>'glutamate metabolic process' SubClassOf 'dicarboxylic acid metabolic process'</newAxiom>
<newAxiom>'glutamate metabolic process' SubClassOf 'glutamine family amino acid metabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006538</classIRI>
<classLabel>glutamate catabolic process</classLabel>
<newAxiom>'glutamate catabolic process' SubClassOf 'cellular amino acid catabolic process'</newAxiom>
<newAxiom>'glutamate catabolic process' SubClassOf 'glutamine family amino acid catabolic process'</newAxiom>
<newAxiom>'glutamate catabolic process' SubClassOf 'has primary input' some 'glutamate(1-)'</newAxiom>
<newAxiom>'glutamate catabolic process' EquivalentTo 'catabolic process' and ('has primary input' some 'glutamate(1-)')</newAxiom>
<newAxiom>'glutamate catabolic process' SubClassOf 'glutamate metabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140678</classIRI>
<classLabel>molecular function inhibitor activity</classLabel>
<newAxiom>'molecular function inhibitor activity' EquivalentTo 'molecular function regulator activity' and ('negatively regulates' some 'molecular_function')</newAxiom>
<newAxiom>'molecular function inhibitor activity' SubClassOf 'molecular function regulator activity'</newAxiom>
<newAxiom>'molecular function inhibitor activity' SubClassOf 'negatively regulates' some 'molecular_function'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140661</classIRI>
<classLabel>cytoskeletal motor inhibitor activity</classLabel>
<newAxiom>'cytoskeletal motor inhibitor activity' SubClassOf 'negatively regulates' some 'cytoskeletal motor activity'</newAxiom>
<newAxiom>'cytoskeletal motor inhibitor activity' SubClassOf 'cytoskeletal motor regulator activity'</newAxiom>
<newAxiom>'cytoskeletal motor inhibitor activity' SubClassOf 'molecular function inhibitor activity'</newAxiom>
<newAxiom>'cytoskeletal motor inhibitor activity' EquivalentTo 'molecular function inhibitor activity' and ('negatively regulates' some 'cytoskeletal motor activity')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044692</classIRI>
<classLabel>exoribonuclease activator activity</classLabel>
<newAxiom>'exoribonuclease activator activity' EquivalentTo 'molecular function activator activity' and ('positively regulates' some 'exoribonuclease activity')</newAxiom>
<newAxiom>'exoribonuclease activator activity' SubClassOf 'enzyme activator activity'</newAxiom>
<newAxiom>'exoribonuclease activator activity' SubClassOf 'positively regulates' some 'exoribonuclease activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018237</classIRI>
<classLabel>urease activator activity</classLabel>
<newAxiom>'urease activator activity' SubClassOf 'enzyme activator activity'</newAxiom>
<newAxiom>'urease activator activity' EquivalentTo 'molecular function activator activity' and ('positively regulates' some 'urease activity')</newAxiom>
<newAxiom>'urease activator activity' SubClassOf 'positively regulates' some 'urease activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044325</classIRI>
<classLabel>transmembrane transporter binding</classLabel>
<newAxiom>'transmembrane transporter binding' SubClassOf 'protein binding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_48121</classIRI>
<classLabel>polyene</classLabel>
<newAxiom>'polyene' SubClassOf 'olefin'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008657</classIRI>
<classLabel>DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity</classLabel>
<newAxiom>'DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity' SubClassOf 'negatively regulates' some 'DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity'</newAxiom>
<newAxiom>'DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity' SubClassOf 'enzyme inhibitor activity'</newAxiom>
<newAxiom>'DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity' SubClassOf 'DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity'</newAxiom>
<newAxiom>'DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity' EquivalentTo 'molecular function inhibitor activity' and ('negatively regulates' some 'DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity')</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071575</classIRI>
<classLabel>integral component of external side of plasma membrane</classLabel>
<newAxiom>'integral component of external side of plasma membrane' EquivalentTo 'integral component of membrane' and ('part of' some 'external side of plasma membrane')</newAxiom>
<newAxiom>'integral component of external side of plasma membrane' SubClassOf 'intrinsic component of external side of plasma membrane'</newAxiom>
<newAxiom>'integral component of external side of plasma membrane' SubClassOf 'integral component of plasma membrane'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000012</classIRI>
<classLabel>somatic nervous system</classLabel>
<newAxiom>'somatic nervous system' SubClassOf 'contributes to morphology of' some 'nervous system'</newAxiom>
<newAxiom>'somatic nervous system' SubClassOf 'organ system subdivision'</newAxiom>
<newAxiom>'somatic nervous system' SubClassOf 'part of' some 'peripheral nervous system'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000444</classIRI>
<classLabel>MIS12/MIND type complex</classLabel>
<newAxiom>'MIS12/MIND type complex' SubClassOf 'part of' some 'kinetochore'</newAxiom>
<newAxiom>'MIS12/MIND type complex' SubClassOf 'protein-containing complex'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098573</classIRI>
<classLabel>intrinsic component of mitochondrial membrane</classLabel>
<newAxiom>'intrinsic component of mitochondrial membrane' EquivalentTo 'intrinsic component of membrane' and ('part of' some 'mitochondrial membrane')</newAxiom>
<newAxiom>'intrinsic component of mitochondrial membrane' SubClassOf 'intrinsic component of organelle membrane'</newAxiom>
<newAxiom>'intrinsic component of mitochondrial membrane' SubClassOf 'part of' some 'mitochondrial membrane'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990873</classIRI>
<classLabel>intrinsic component of plasma membrane of cell tip</classLabel>
<newAxiom>'intrinsic component of plasma membrane of cell tip' SubClassOf 'part of' some 'plasma membrane of cell tip'</newAxiom>
<newAxiom>'intrinsic component of plasma membrane of cell tip' EquivalentTo 'intrinsic component of membrane' and ('part of' some 'plasma membrane of cell tip')</newAxiom>
<newAxiom>'intrinsic component of plasma membrane of cell tip' SubClassOf 'intrinsic component of plasma membrane'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990919</classIRI>
<classLabel>proteasome-nuclear membrane anchor activity</classLabel>
<newAxiom>'proteasome-nuclear membrane anchor activity' SubClassOf 'protein-membrane adaptor activity'</newAxiom>
<newAxiom>'proteasome-nuclear membrane anchor activity' EquivalentTo 'protein-membrane adaptor activity' and ('part of' some 'proteasome localization to nuclear periphery')</newAxiom>
<newAxiom>'proteasome-nuclear membrane anchor activity' SubClassOf 'part of' some 'proteasome localization to nuclear periphery'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005639</classIRI>
<classLabel>integral component of nuclear inner membrane</classLabel>
<newAxiom>'integral component of nuclear inner membrane' SubClassOf 'integral component of organelle membrane'</newAxiom>
<newAxiom>'integral component of nuclear inner membrane' SubClassOf 'intrinsic component of nuclear inner membrane'</newAxiom>
<newAxiom>'integral component of nuclear inner membrane' EquivalentTo 'integral component of membrane' and ('part of' some 'nuclear inner membrane')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900049</classIRI>
<classLabel>regulation of histone exchange</classLabel>
<newAxiom>'regulation of histone exchange' EquivalentTo 'biological regulation' and ('regulates' some 'histone exchange')</newAxiom>
<newAxiom>'regulation of histone exchange' SubClassOf 'regulation of chromatin organization'</newAxiom>
<newAxiom>'regulation of histone exchange' SubClassOf 'regulates' some 'histone exchange'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900050</classIRI>
<classLabel>negative regulation of histone exchange</classLabel>
<newAxiom>'negative regulation of histone exchange' SubClassOf 'negatively regulates' some 'histone exchange'</newAxiom>
<newAxiom>'negative regulation of histone exchange' SubClassOf 'negative regulation of chromatin organization'</newAxiom>
<newAxiom>'negative regulation of histone exchange' SubClassOf 'regulation of histone exchange'</newAxiom>
<newAxiom>'negative regulation of histone exchange' EquivalentTo 'biological regulation' and ('negatively regulates' some 'histone exchange')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900051</classIRI>
<classLabel>positive regulation of histone exchange</classLabel>
<newAxiom>'positive regulation of histone exchange' EquivalentTo 'biological regulation' and ('positively regulates' some 'histone exchange')</newAxiom>
<newAxiom>'positive regulation of histone exchange' SubClassOf 'positive regulation of chromatin organization'</newAxiom>
<newAxiom>'positive regulation of histone exchange' SubClassOf 'positively regulates' some 'histone exchange'</newAxiom>
<newAxiom>'positive regulation of histone exchange' SubClassOf 'regulation of histone exchange'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030176</classIRI>
<classLabel>integral component of endoplasmic reticulum membrane</classLabel>
<newAxiom>'integral component of endoplasmic reticulum membrane' SubClassOf 'intrinsic component of endoplasmic reticulum membrane'</newAxiom>
<newAxiom>'integral component of endoplasmic reticulum membrane' EquivalentTo 'integral component of membrane' and ('part of' some 'endoplasmic reticulum membrane')</newAxiom>
<newAxiom>'integral component of endoplasmic reticulum membrane' SubClassOf 'integral component of organelle membrane'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031465</classIRI>
<classLabel>Cul4B-RING E3 ubiquitin ligase complex</classLabel>
<newAxiom>'Cul4B-RING E3 ubiquitin ligase complex' SubClassOf 'Cul4-RING E3 ubiquitin ligase complex'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031302</classIRI>
<classLabel>intrinsic component of endosome membrane</classLabel>
<newAxiom>'intrinsic component of endosome membrane' EquivalentTo 'intrinsic component of membrane' and ('part of' some 'endosome membrane')</newAxiom>
<newAxiom>'intrinsic component of endosome membrane' SubClassOf 'intrinsic component of organelle membrane'</newAxiom>
<newAxiom>'intrinsic component of endosome membrane' SubClassOf 'part of' some 'endosome membrane'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031304</classIRI>
<classLabel>intrinsic component of mitochondrial inner membrane</classLabel>
<newAxiom>'intrinsic component of mitochondrial inner membrane' SubClassOf 'intrinsic component of mitochondrial membrane'</newAxiom>
<newAxiom>'intrinsic component of mitochondrial inner membrane' SubClassOf 'part of' some 'mitochondrial inner membrane'</newAxiom>
<newAxiom>'intrinsic component of mitochondrial inner membrane' EquivalentTo 'intrinsic component of membrane' and ('part of' some 'mitochondrial inner membrane')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031303</classIRI>
<classLabel>integral component of endosome membrane</classLabel>
<newAxiom>'integral component of endosome membrane' SubClassOf 'intrinsic component of endosome membrane'</newAxiom>
<newAxiom>'integral component of endosome membrane' SubClassOf 'integral component of organelle membrane'</newAxiom>
<newAxiom>'integral component of endosome membrane' EquivalentTo 'integral component of membrane' and ('part of' some 'endosome membrane')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031305</classIRI>
<classLabel>integral component of mitochondrial inner membrane</classLabel>
<newAxiom>'integral component of mitochondrial inner membrane' SubClassOf 'intrinsic component of mitochondrial inner membrane'</newAxiom>
<newAxiom>'integral component of mitochondrial inner membrane' EquivalentTo 'integral component of membrane' and ('part of' some 'mitochondrial inner membrane')</newAxiom>
<newAxiom>'integral component of mitochondrial inner membrane' SubClassOf 'integral component of mitochondrial membrane'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032592</classIRI>
<classLabel>integral component of mitochondrial membrane</classLabel>
<newAxiom>'integral component of mitochondrial membrane' EquivalentTo 'integral component of membrane' and ('part of' some 'mitochondrial membrane')</newAxiom>
<newAxiom>'integral component of mitochondrial membrane' SubClassOf 'intrinsic component of mitochondrial membrane'</newAxiom>
<newAxiom>'integral component of mitochondrial membrane' SubClassOf 'integral component of organelle membrane'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045815</classIRI>
<classLabel>epigenetic maintenance of chromatin in transcription-competent conformation</classLabel>
<newAxiom>'epigenetic maintenance of chromatin in transcription-competent conformation' EquivalentTo 'epigenetic regulation of gene expression' and ('positively regulates' some 'gene expression')</newAxiom>
<newAxiom>'epigenetic maintenance of chromatin in transcription-competent conformation' SubClassOf 'positive regulation of gene expression'</newAxiom>
<newAxiom>'epigenetic maintenance of chromatin in transcription-competent conformation' SubClassOf 'chromatin remodeling'</newAxiom>
<newAxiom>'epigenetic maintenance of chromatin in transcription-competent conformation' SubClassOf 'epigenetic regulation of gene expression'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031227</classIRI>
<classLabel>intrinsic component of endoplasmic reticulum membrane</classLabel>
<newAxiom>'intrinsic component of endoplasmic reticulum membrane' SubClassOf 'part of' some 'endoplasmic reticulum membrane'</newAxiom>
<newAxiom>'intrinsic component of endoplasmic reticulum membrane' EquivalentTo 'intrinsic component of membrane' and ('part of' some 'endoplasmic reticulum membrane')</newAxiom>
<newAxiom>'intrinsic component of endoplasmic reticulum membrane' SubClassOf 'intrinsic component of organelle membrane'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031229</classIRI>
<classLabel>intrinsic component of nuclear inner membrane</classLabel>
<newAxiom>'intrinsic component of nuclear inner membrane' SubClassOf 'intrinsic component of organelle membrane'</newAxiom>
<newAxiom>'intrinsic component of nuclear inner membrane' EquivalentTo 'intrinsic component of membrane' and ('part of' some 'nuclear inner membrane')</newAxiom>
<newAxiom>'intrinsic component of nuclear inner membrane' SubClassOf 'part of' some 'nuclear inner membrane'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031233</classIRI>
<classLabel>intrinsic component of external side of plasma membrane</classLabel>
<newAxiom>'intrinsic component of external side of plasma membrane' EquivalentTo 'intrinsic component of plasma membrane' and ('part of' some 'external side of plasma membrane')</newAxiom>
<newAxiom>'intrinsic component of external side of plasma membrane' SubClassOf 'part of' some 'external side of plasma membrane'</newAxiom>
<newAxiom>'intrinsic component of external side of plasma membrane' SubClassOf 'intrinsic component of plasma membrane'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_3011048</classIRI>
<classLabel>genital system</classLabel>
<newAxiom>'genital system' SubClassOf 'anatomical system'</newAxiom>
<newAxiom>'genital system' SubClassOf 'part of' some 'genitourinary system'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031033</classIRI>
<classLabel>myosin filament organization</classLabel>
<newAxiom>'myosin filament organization' SubClassOf 'actin cytoskeleton organization'</newAxiom>
<newAxiom>'myosin filament organization' SubClassOf 'supramolecular fiber organization'</newAxiom>
</deletedClass>
</deletedClasses>
</diffReport>