<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
27
</numberChangedClasses>
<numberNewClasses>
28
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010008</classIRI>
<classLabel>endosome membrane</classLabel>
<deletedAxiom>&apos;endosome membrane&apos; SubClassOf &apos;whole membrane&apos;</deletedAxiom>
<newAxiom>&apos;endosome membrane&apos; SubClassOf &apos;vacuolar membrane&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036010</classIRI>
<classLabel>protein localization to endosome</classLabel>
<newAxiom>&apos;protein localization to endosome&apos; SubClassOf &apos;protein localization to vacuole&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005771</classIRI>
<classLabel>multivesicular body</classLabel>
<deletedAxiom>&apos;multivesicular body&apos; SubClassOf &apos;endosome&apos;</deletedAxiom>
<newAxiom>&apos;multivesicular body&apos; SubClassOf &apos;late endosome&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005768</classIRI>
<classLabel>endosome</classLabel>
<deletedAxiom>&apos;endosome&apos; SubClassOf &apos;intracellular membrane-bounded organelle&apos;</deletedAxiom>
<newAxiom>&apos;endosome&apos; SubClassOf &apos;vacuole&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904980</classIRI>
<classLabel>positive regulation of endosome organization</classLabel>
<newAxiom>&apos;positive regulation of endosome organization&apos; SubClassOf &apos;positive regulation of vacuole organization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904978</classIRI>
<classLabel>regulation of endosome organization</classLabel>
<newAxiom>&apos;regulation of endosome organization&apos; SubClassOf &apos;regulation of vacuole organization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902955</classIRI>
<classLabel>positive regulation of early endosome to recycling endosome transport</classLabel>
<newAxiom>&apos;positive regulation of early endosome to recycling endosome transport&apos; SubClassOf &apos;positive regulation of vacuolar transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902954</classIRI>
<classLabel>regulation of early endosome to recycling endosome transport</classLabel>
<newAxiom>&apos;regulation of early endosome to recycling endosome transport&apos; SubClassOf &apos;regulation of vacuolar transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098866</classIRI>
<classLabel>multivesicular body fusion to apical plasma membrane</classLabel>
<newAxiom>&apos;multivesicular body fusion to apical plasma membrane&apos; SubClassOf &apos;vacuole fusion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031303</classIRI>
<classLabel>integral component of endosome membrane</classLabel>
<newAxiom>&apos;integral component of endosome membrane&apos; SubClassOf &apos;integral component of vacuolar membrane&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031302</classIRI>
<classLabel>intrinsic component of endosome membrane</classLabel>
<newAxiom>&apos;intrinsic component of endosome membrane&apos; SubClassOf &apos;intrinsic component of vacuolar membrane&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031313</classIRI>
<classLabel>extrinsic component of endosome membrane</classLabel>
<newAxiom>&apos;extrinsic component of endosome membrane&apos; SubClassOf &apos;extrinsic component of vacuolar membrane&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016189</classIRI>
<classLabel>synaptic vesicle to endosome fusion</classLabel>
<newAxiom>&apos;synaptic vesicle to endosome fusion&apos; SubClassOf &apos;vesicle fusion with vacuole&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016197</classIRI>
<classLabel>endosomal transport</classLabel>
<newAxiom>&apos;endosomal transport&apos; SubClassOf &apos;vacuolar transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000642</classIRI>
<classLabel>negative regulation of early endosome to late endosome transport</classLabel>
<newAxiom>&apos;negative regulation of early endosome to late endosome transport&apos; SubClassOf &apos;negative regulation of vacuolar transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000643</classIRI>
<classLabel>positive regulation of early endosome to late endosome transport</classLabel>
<newAxiom>&apos;positive regulation of early endosome to late endosome transport&apos; SubClassOf &apos;positive regulation of vacuolar transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000641</classIRI>
<classLabel>regulation of early endosome to late endosome transport</classLabel>
<newAxiom>&apos;regulation of early endosome to late endosome transport&apos; SubClassOf &apos;regulation of vacuolar transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031904</classIRI>
<classLabel>endosome lumen</classLabel>
<newAxiom>&apos;endosome lumen&apos; SubClassOf &apos;vacuolar lumen&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902502</classIRI>
<classLabel>multivesicular body HOPS complex</classLabel>
<newAxiom>&apos;multivesicular body HOPS complex&apos; SubClassOf &apos;vacuolar HOPS complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001135</classIRI>
<classLabel>regulation of endocytic recycling</classLabel>
<newAxiom>&apos;regulation of endocytic recycling&apos; SubClassOf &apos;regulation of vacuolar transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001136</classIRI>
<classLabel>negative regulation of endocytic recycling</classLabel>
<newAxiom>&apos;negative regulation of endocytic recycling&apos; SubClassOf &apos;negative regulation of vacuolar transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001137</classIRI>
<classLabel>positive regulation of endocytic recycling</classLabel>
<newAxiom>&apos;positive regulation of endocytic recycling&apos; SubClassOf &apos;positive regulation of vacuolar transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006895</classIRI>
<classLabel>Golgi to endosome transport</classLabel>
<newAxiom>&apos;Golgi to endosome transport&apos; SubClassOf &apos;Golgi to vacuole transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097489</classIRI>
<classLabel>multivesicular body, internal vesicle lumen</classLabel>
<newAxiom>&apos;multivesicular body, internal vesicle lumen&apos; SubClassOf &apos;vacuolar lumen&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032510</classIRI>
<classLabel>endosome to lysosome transport via multivesicular body sorting pathway</classLabel>
<deletedAxiom>&apos;endosome to lysosome transport via multivesicular body sorting pathway&apos; SubClassOf &apos;early endosome to late endosome transport&apos;</deletedAxiom>
<newAxiom>&apos;endosome to lysosome transport via multivesicular body sorting pathway&apos; SubClassOf &apos;endosome to lysosome transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044440</classIRI>
<classLabel>endosomal part</classLabel>
<newAxiom>&apos;endosomal part&apos; SubClassOf &apos;vacuolar part&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007032</classIRI>
<classLabel>endosome organization</classLabel>
<newAxiom>&apos;endosome organization&apos; SubClassOf &apos;vacuole organization&apos;</newAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905148</classIRI>
<classLabel>negative regulation of smooth muscle hypertrophy</classLabel>
<newAxiom>'negative regulation of smooth muscle hypertrophy' SubClassOf 'negative regulation of muscle adaptation'</newAxiom>
<newAxiom>'negative regulation of smooth muscle hypertrophy' EquivalentTo 'biological regulation' and ('negatively regulates' some 'smooth muscle hypertrophy')</newAxiom>
<newAxiom>'negative regulation of smooth muscle hypertrophy' SubClassOf 'regulation of smooth muscle hypertrophy'</newAxiom>
<newAxiom>'negative regulation of smooth muscle hypertrophy' SubClassOf 'negatively regulates' some 'smooth muscle hypertrophy'</newAxiom>
<newAxiom>'negative regulation of smooth muscle hypertrophy' SubClassOf 'negative regulation of muscle hypertrophy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905149</classIRI>
<classLabel>positive regulation of smooth muscle hypertrophy</classLabel>
<newAxiom>'positive regulation of smooth muscle hypertrophy' SubClassOf 'positive regulation of muscle adaptation'</newAxiom>
<newAxiom>'positive regulation of smooth muscle hypertrophy' SubClassOf 'positively regulates' some 'smooth muscle hypertrophy'</newAxiom>
<newAxiom>'positive regulation of smooth muscle hypertrophy' SubClassOf 'positive regulation of muscle hypertrophy'</newAxiom>
<newAxiom>'positive regulation of smooth muscle hypertrophy' EquivalentTo 'biological regulation' and ('positively regulates' some 'smooth muscle hypertrophy')</newAxiom>
<newAxiom>'positive regulation of smooth muscle hypertrophy' SubClassOf 'regulation of smooth muscle hypertrophy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905147</classIRI>
<classLabel>regulation of smooth muscle hypertrophy</classLabel>
<newAxiom>'regulation of smooth muscle hypertrophy' SubClassOf 'regulation of muscle hypertrophy'</newAxiom>
<newAxiom>'regulation of smooth muscle hypertrophy' EquivalentTo 'biological regulation' and ('regulates' some 'smooth muscle hypertrophy')</newAxiom>
<newAxiom>'regulation of smooth muscle hypertrophy' SubClassOf 'regulates' some 'smooth muscle hypertrophy'</newAxiom>
<newAxiom>'regulation of smooth muscle hypertrophy' SubClassOf 'regulation of muscle adaptation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061763</classIRI>
<classLabel>multivesicular body-lysosome fusion</classLabel>
<newAxiom>'multivesicular body-lysosome fusion' SubClassOf 'results_in_fusion_of' some 'lysosomal membrane'</newAxiom>
<newAxiom>'multivesicular body-lysosome fusion' SubClassOf 'results_in_fusion_of' some 'multivesicular body membrane'</newAxiom>
<newAxiom>'multivesicular body-lysosome fusion' EquivalentTo 'membrane fusion' and ('results_in_fusion_of' some 'lysosomal membrane') and ('results_in_fusion_of' some 'multivesicular body membrane')</newAxiom>
<newAxiom>'multivesicular body-lysosome fusion' SubClassOf 'part of' some 'endosome to lysosome transport via multivesicular body sorting pathway'</newAxiom>
<newAxiom>'multivesicular body-lysosome fusion' SubClassOf 'organelle membrane fusion'</newAxiom>
<newAxiom>'multivesicular body-lysosome fusion' SubClassOf 'vacuole fusion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102739</classIRI>
<classLabel>(gibberellin-36), 2-oxoglutarate:oxygen oxidoreductase activity</classLabel>
<newAxiom>'(gibberellin-36), 2-oxoglutarate:oxygen oxidoreductase activity' SubClassOf 'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102738</classIRI>
<classLabel>(gibberellin-14), 2-oxoglutarate:oxygen oxidoreductase activity</classLabel>
<newAxiom>'(gibberellin-14), 2-oxoglutarate:oxygen oxidoreductase activity' SubClassOf 'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102737</classIRI>
<classLabel>p-coumaroyltriacetic acid synthase activity</classLabel>
<newAxiom>'p-coumaroyltriacetic acid synthase activity' SubClassOf 'transferase activity, transferring acyl groups other than amino-acyl groups'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102169</classIRI>
<classLabel>pyocyanin hydroxylase activity</classLabel>
<newAxiom>'pyocyanin hydroxylase activity' SubClassOf 'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102161</classIRI>
<classLabel>copal-8-ol diphosphate synthase activity</classLabel>
<newAxiom>'copal-8-ol diphosphate synthase activity' SubClassOf 'hydro-lyase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102160</classIRI>
<classLabel>cyanidin-3-O-glucoside 2-O-glucuronosyltransferase activity</classLabel>
<newAxiom>'cyanidin-3-O-glucoside 2-O-glucuronosyltransferase activity' SubClassOf 'transferase activity, transferring hexosyl groups'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102176</classIRI>
<classLabel>cycloeucalenone reductase activity</classLabel>
<newAxiom>'cycloeucalenone reductase activity' SubClassOf 'oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102159</classIRI>
<classLabel>baicalein 7-O-glucuronosyltransferase activity</classLabel>
<newAxiom>'baicalein 7-O-glucuronosyltransferase activity' SubClassOf 'transferase activity, transferring hexosyl groups'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102383</classIRI>
<classLabel>steviol glucosyltransferase activity</classLabel>
<newAxiom>'steviol glucosyltransferase activity' SubClassOf 'transferase activity, transferring hexosyl groups'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102384</classIRI>
<classLabel>19-O-beta-glucopyranosyl-steviol glucosyltransferase activity</classLabel>
<newAxiom>'19-O-beta-glucopyranosyl-steviol glucosyltransferase activity' SubClassOf 'transferase activity, transferring hexosyl groups'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102385</classIRI>
<classLabel>patchoulol synthase activity</classLabel>
<newAxiom>'patchoulol synthase activity' SubClassOf 'carbon-oxygen lyase activity, acting on phosphates'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102581</classIRI>
<classLabel>cyanidin 3-O-glucoside-p-coumaroyltransferase activity</classLabel>
<newAxiom>'cyanidin 3-O-glucoside-p-coumaroyltransferase activity' SubClassOf 'transferase activity, transferring acyl groups other than amino-acyl groups'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102580</classIRI>
<classLabel>cyanidin 3-O-glucoside 2-O"-xylosyltransferase activity</classLabel>
<newAxiom>'cyanidin 3-O-glucoside 2-O"-xylosyltransferase activity' SubClassOf 'transferase activity, transferring pentosyl groups'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102583</classIRI>
<classLabel>cyanidin 3-O-glucoside-(2"-O-xyloside) 6"-O-acyltransferase activity</classLabel>
<newAxiom>'cyanidin 3-O-glucoside-(2"-O-xyloside) 6"-O-acyltransferase activity' SubClassOf 'transferase activity, transferring acyl groups other than amino-acyl groups'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102582</classIRI>
<classLabel>cyanidin 3-O-p-coumaroylglucoside 2-O"-xylosyltransferase activity</classLabel>
<newAxiom>'cyanidin 3-O-p-coumaroylglucoside 2-O"-xylosyltransferase activity' SubClassOf 'transferase activity, transferring pentosyl groups'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102589</classIRI>
<classLabel>cyanidin 3-O-glucoside 3",6"-O-dimalonyltransferase activity</classLabel>
<newAxiom>'cyanidin 3-O-glucoside 3",6"-O-dimalonyltransferase activity' SubClassOf 'transferase activity, transferring acyl groups other than amino-acyl groups'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102588</classIRI>
<classLabel>cyanidin 3-O-glucoside 6"-O-malonyltransferase activity</classLabel>
<newAxiom>'cyanidin 3-O-glucoside 6"-O-malonyltransferase activity' SubClassOf 'transferase activity, transferring acyl groups other than amino-acyl groups'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102614</classIRI>
<classLabel>germacrene A acid 8beta-hydroxylase activity</classLabel>
<newAxiom>'germacrene A acid 8beta-hydroxylase activity' SubClassOf 'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102613</classIRI>
<classLabel>trimethyluric acid monooxygenase activity</classLabel>
<newAxiom>'trimethyluric acid monooxygenase activity' SubClassOf 'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103032</classIRI>
<classLabel>tartronate semialdehyde reductase activity</classLabel>
<newAxiom>'tartronate semialdehyde reductase activity' SubClassOf 'oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103069</classIRI>
<classLabel>17-hydroxyprogesterone 21-hydroxylase activity</classLabel>
<newAxiom>'17-hydroxyprogesterone 21-hydroxylase activity' SubClassOf 'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103058</classIRI>
<classLabel>kaempferol 3-glucoside 7-O-rhamnosyltransferase activity</classLabel>
<newAxiom>'kaempferol 3-glucoside 7-O-rhamnosyltransferase activity' SubClassOf 'transferase activity, transferring hexosyl groups'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103019</classIRI>
<classLabel>undecaprenyl phosphate-L-Ara4FN transferase activity</classLabel>
<newAxiom>'undecaprenyl phosphate-L-Ara4FN transferase activity' SubClassOf 'transferase activity, transferring pentosyl groups'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103011</classIRI>
<classLabel>mannosylfructose-phosphate synthase activity</classLabel>
<newAxiom>'mannosylfructose-phosphate synthase activity' SubClassOf 'transferase activity, transferring hexosyl groups'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>