<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
98
</numberChangedClasses>
<numberNewClasses>
21
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019207</classIRI>
<classLabel>kinase regulator activity</classLabel>
<newAxiom>&apos;kinase regulator activity&apos; SubClassOf &apos;directly regulates&apos; some &apos;kinase activity&apos;</newAxiom>
<newAxiom>&apos;kinase regulator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly regulates&apos; some &apos;kinase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019208</classIRI>
<classLabel>phosphatase regulator activity</classLabel>
<newAxiom>&apos;phosphatase regulator activity&apos; SubClassOf &apos;directly regulates&apos; some &apos;phosphatase activity&apos;</newAxiom>
<newAxiom>&apos;phosphatase regulator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly regulates&apos; some &apos;phosphatase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019209</classIRI>
<classLabel>kinase activator activity</classLabel>
<deletedAxiom>&apos;kinase activator activity&apos; SubClassOf &apos;positively regulates&apos; some &apos;kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;kinase activator activity&apos; SubClassOf &apos;kinase regulator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;kinase activator activity&apos; SubClassOf &apos;enzyme activator activity&apos;</deletedAxiom>
<newAxiom>&apos;kinase activator activity&apos; SubClassOf &apos;directly activates&apos; some &apos;kinase activity&apos;</newAxiom>
<newAxiom>&apos;kinase activator activity&apos; SubClassOf &apos;kinase regulator activity&apos;</newAxiom>
<newAxiom>&apos;kinase activator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly activates&apos; some &apos;kinase activity&apos;)</newAxiom>
<newAxiom>&apos;kinase activator activity&apos; SubClassOf &apos;enzyme activator activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019210</classIRI>
<classLabel>kinase inhibitor activity</classLabel>
<newAxiom>&apos;kinase inhibitor activity&apos; SubClassOf &apos;directly inhibits&apos; some &apos;kinase activity&apos;</newAxiom>
<newAxiom>&apos;kinase inhibitor activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly inhibits&apos; some &apos;kinase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019211</classIRI>
<classLabel>phosphatase activator activity</classLabel>
<deletedAxiom>&apos;phosphatase activator activity&apos; SubClassOf &apos;phosphatase regulator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;phosphatase activator activity&apos; SubClassOf &apos;positively regulates&apos; some &apos;phosphatase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;phosphatase activator activity&apos; SubClassOf &apos;enzyme activator activity&apos;</deletedAxiom>
<newAxiom>&apos;phosphatase activator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly activates&apos; some &apos;phosphatase activity&apos;)</newAxiom>
<newAxiom>&apos;phosphatase activator activity&apos; SubClassOf &apos;phosphatase regulator activity&apos;</newAxiom>
<newAxiom>&apos;phosphatase activator activity&apos; SubClassOf &apos;directly activates&apos; some &apos;phosphatase activity&apos;</newAxiom>
<newAxiom>&apos;phosphatase activator activity&apos; SubClassOf &apos;enzyme activator activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019212</classIRI>
<classLabel>phosphatase inhibitor activity</classLabel>
<deletedAxiom>&apos;phosphatase inhibitor activity&apos; SubClassOf &apos;phosphatase regulator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;phosphatase inhibitor activity&apos; SubClassOf &apos;negatively regulates&apos; some &apos;phosphatase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;phosphatase inhibitor activity&apos; SubClassOf &apos;enzyme inhibitor activity&apos;</deletedAxiom>
<newAxiom>&apos;phosphatase inhibitor activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly inhibits&apos; some &apos;phosphatase activity&apos;)</newAxiom>
<newAxiom>&apos;phosphatase inhibitor activity&apos; SubClassOf &apos;phosphatase regulator activity&apos;</newAxiom>
<newAxiom>&apos;phosphatase inhibitor activity&apos; SubClassOf &apos;directly inhibits&apos; some &apos;phosphatase activity&apos;</newAxiom>
<newAxiom>&apos;phosphatase inhibitor activity&apos; SubClassOf &apos;enzyme inhibitor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019182</classIRI>
<classLabel>histamine-gated chloride channel activity</classLabel>
<newAxiom>&apos;histamine-gated chloride channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099095</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044091</classIRI>
<classLabel>membrane biogenesis</classLabel>
<deletedAxiom>&apos;membrane biogenesis&apos; SubClassOf &apos;cellular component biogenesis&apos;</deletedAxiom>
<newAxiom>&apos;membrane biogenesis&apos; SubClassOf &apos;has output&apos; some &apos;membrane&apos;</newAxiom>
<newAxiom>&apos;membrane biogenesis&apos; EquivalentTo &apos;cellular component biogenesis&apos; and (&apos;has output&apos; some &apos;membrane&apos;)</newAxiom>
<newAxiom>&apos;membrane biogenesis&apos; SubClassOf &apos;cellular component biogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034414</classIRI>
<classLabel>tRNA 3&apos;-trailer cleavage, endonucleolytic</classLabel>
<newAxiom>&apos;tRNA 3&apos;-trailer cleavage, endonucleolytic&apos; SubClassOf &apos;endonucleolytic cleavage involved in tRNA processing&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097741</classIRI>
<classLabel>mastigoneme</classLabel>
<newAxiom>&apos;mastigoneme&apos; SubClassOf &apos;only in taxon&apos; some http://purl.obolibrary.org/obo/NCBITaxon_Union_0000031</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097214</classIRI>
<classLabel>positive regulation of lysosomal membrane permeability</classLabel>
<newAxiom>&apos;positive regulation of lysosomal membrane permeability&apos; SubClassOf &apos;positive regulation of regulation of membrane permeability&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097215</classIRI>
<classLabel>negative regulation of lysosomal membrane permeability</classLabel>
<newAxiom>&apos;negative regulation of lysosomal membrane permeability&apos; SubClassOf &apos;negative regulation of regulation of membrane permeability&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000310</classIRI>
<classLabel>regulation of N-methyl-D-aspartate selective glutamate receptor activity</classLabel>
<deletedAxiom>&apos;regulation of N-methyl-D-aspartate selective glutamate receptor activity&apos; SubClassOf &apos;regulation of ion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;regulation of N-methyl-D-aspartate selective glutamate receptor activity&apos; SubClassOf &apos;regulation of cation channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000312</classIRI>
<classLabel>regulation of kainate selective glutamate receptor activity</classLabel>
<deletedAxiom>&apos;regulation of kainate selective glutamate receptor activity&apos; SubClassOf &apos;regulation of ion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;regulation of kainate selective glutamate receptor activity&apos; SubClassOf &apos;regulation of cation channel activity&apos;</newAxiom>
<newAxiom>&apos;regulation of kainate selective glutamate receptor activity&apos; SubClassOf &apos;regulation of potassium ion transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;regulation of kainate selective glutamate receptor activity&apos; SubClassOf &apos;regulation of sodium ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905710</classIRI>
<classLabel>positive regulation of regulation of membrane permeability</classLabel>
<deletedAxiom>&apos;positive regulation of regulation of membrane permeability&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;regulation of membrane permeability&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of regulation of membrane permeability&apos; SubClassOf &apos;positively regulates&apos; some &apos;regulation of membrane permeability&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of regulation of membrane permeability&apos; SubClassOf &apos;regulation of biological quality&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of regulation of membrane permeability&apos; SubClassOf &apos;positive regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of regulation of membrane permeability&apos; SubClassOf &apos;regulation of membrane permeability&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004972</classIRI>
<classLabel>NMDA glutamate receptor activity</classLabel>
<newAxiom>&apos;NMDA glutamate receptor activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099094</newAxiom>
<newAxiom>&apos;NMDA glutamate receptor activity&apos; SubClassOf &apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_36915</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004857</classIRI>
<classLabel>enzyme inhibitor activity</classLabel>
<deletedAxiom>&apos;enzyme inhibitor activity&apos; SubClassOf &apos;enzyme regulator activity&apos;</deletedAxiom>
<newAxiom>&apos;enzyme inhibitor activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly inhibits&apos; some &apos;catalytic activity&apos;)</newAxiom>
<newAxiom>&apos;enzyme inhibitor activity&apos; SubClassOf &apos;enzyme regulator activity&apos;</newAxiom>
<newAxiom>&apos;enzyme inhibitor activity&apos; SubClassOf &apos;directly inhibits&apos; some &apos;catalytic activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004860</classIRI>
<classLabel>protein kinase inhibitor activity</classLabel>
<newAxiom>&apos;protein kinase inhibitor activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly inhibits&apos; some &apos;protein tyrosine kinase activity&apos;)</newAxiom>
<newAxiom>&apos;protein kinase inhibitor activity&apos; SubClassOf &apos;directly inhibits&apos; some &apos;protein tyrosine kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004864</classIRI>
<classLabel>protein phosphatase inhibitor activity</classLabel>
<newAxiom>&apos;protein phosphatase inhibitor activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly inhibits&apos; some &apos;phosphoprotein phosphatase activity&apos;)</newAxiom>
<newAxiom>&apos;protein phosphatase inhibitor activity&apos; SubClassOf &apos;directly inhibits&apos; some &apos;phosphoprotein phosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038177</classIRI>
<classLabel>death receptor agonist activity</classLabel>
<newAxiom>&apos;death receptor agonist activity&apos; SubClassOf &apos;directly activates&apos; some http://purl.obolibrary.org/obo/PR_000021999</newAxiom>
<newAxiom>&apos;death receptor agonist activity&apos; EquivalentTo &apos;receptor agonist activity&apos; and (&apos;directly activates&apos; some http://purl.obolibrary.org/obo/PR_000021999)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014069</classIRI>
<classLabel>postsynaptic density</classLabel>
<deletedAxiom>&apos;postsynaptic density&apos; SubClassOf &apos;neuron part&apos;</deletedAxiom>
<deletedAxiom>&apos;postsynaptic density&apos; SubClassOf &apos;postsynaptic specialization&apos;</deletedAxiom>
<deletedAxiom>&apos;postsynaptic density&apos; SubClassOf &apos;part of&apos; some &apos;excitatory synapse&apos;</deletedAxiom>
<newAxiom>&apos;postsynaptic density&apos; EquivalentTo &apos;postsynaptic specialization&apos; and (&apos;part of&apos; some &apos;asymmetric synapse&apos;)</newAxiom>
<newAxiom>&apos;postsynaptic density&apos; SubClassOf &apos;postsynaptic specialization&apos;</newAxiom>
<newAxiom>&apos;postsynaptic density&apos; SubClassOf &apos;part of&apos; some &apos;asymmetric synapse&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901029</classIRI>
<classLabel>negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway</classLabel>
<deletedAxiom>&apos;negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway&apos; SubClassOf &apos;negative regulation of regulation of membrane permeability&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901030</classIRI>
<classLabel>positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway</classLabel>
<deletedAxiom>&apos;positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway&apos; SubClassOf &apos;positive regulation of regulation of membrane permeability&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043679</classIRI>
<classLabel>axon terminus</classLabel>
<deletedAxiom>&apos;axon terminus&apos; SubClassOf &apos;axon part&apos;</deletedAxiom>
<newAxiom>&apos;axon terminus&apos; SubClassOf &apos;presynapse&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045313</classIRI>
<classLabel>rhabdomere membrane biogenesis</classLabel>
<deletedAxiom>&apos;rhabdomere membrane biogenesis&apos; SubClassOf &apos;membrane biogenesis&apos;</deletedAxiom>
<newAxiom>&apos;rhabdomere membrane biogenesis&apos; SubClassOf &apos;membrane biogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035735</classIRI>
<classLabel>intraciliary transport involved in cilium assembly</classLabel>
<deletedAxiom>&apos;intraciliary transport involved in cilium assembly&apos; SubClassOf &apos;part of&apos; some &apos;cilium assembly&apos;</deletedAxiom>
<newAxiom>&apos;intraciliary transport involved in cilium assembly&apos; SubClassOf &apos;part of&apos; some &apos;cilium assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035794</classIRI>
<classLabel>positive regulation of mitochondrial membrane permeability</classLabel>
<newAxiom>&apos;positive regulation of mitochondrial membrane permeability&apos; SubClassOf &apos;positive regulation of regulation of membrane permeability&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035795</classIRI>
<classLabel>negative regulation of mitochondrial membrane permeability</classLabel>
<newAxiom>&apos;negative regulation of mitochondrial membrane permeability&apos; SubClassOf &apos;negative regulation of regulation of membrane permeability&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070062</classIRI>
<classLabel>extracellular exosome</classLabel>
<deletedAxiom>&apos;extracellular exosome&apos; SubClassOf &apos;extracellular vesicle&apos;</deletedAxiom>
<newAxiom>&apos;extracellular exosome&apos; SubClassOf &apos;vesicle&apos;</newAxiom>
<newAxiom>&apos;extracellular exosome&apos; SubClassOf &apos;extracellular vesicle&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035424</classIRI>
<classLabel>MAPK import into nucleus involved in innate immune response</classLabel>
<newAxiom>&apos;MAPK import into nucleus involved in innate immune response&apos; SubClassOf &apos;single-organism cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098966</classIRI>
<classLabel>perisynaptic extracellular matrix</classLabel>
<deletedAxiom>&apos;perisynaptic extracellular matrix&apos; SubClassOf &apos;part of&apos; some &apos;synaptic cleft&apos;</deletedAxiom>
<deletedAxiom>&apos;perisynaptic extracellular matrix&apos; SubClassOf &apos;synapse part&apos;</deletedAxiom>
<newAxiom>&apos;perisynaptic extracellular matrix&apos; SubClassOf &apos;part of&apos; some &apos;perisynaptic space&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098970</classIRI>
<classLabel>postsynaptic neurotransmitter receptor diffusion trapping</classLabel>
<deletedAxiom>&apos;postsynaptic neurotransmitter receptor diffusion trapping&apos; SubClassOf &apos;occurs in&apos; some &apos;postsynaptic membrane&apos;</deletedAxiom>
<newAxiom>&apos;postsynaptic neurotransmitter receptor diffusion trapping&apos; SubClassOf &apos;occurs in&apos; some &apos;postsynaptic membrane&apos;</newAxiom>
<newAxiom>&apos;postsynaptic neurotransmitter receptor diffusion trapping&apos; SubClassOf &apos;occurs in&apos; some &apos;postsynaptic specialization membrane&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001948</classIRI>
<classLabel>glycoprotein binding</classLabel>
<newAxiom>&apos;glycoprotein binding&apos; SubClassOf &apos;protein binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098948</classIRI>
<classLabel>intrinsic component of postsynaptic specialization membrane</classLabel>
<newAxiom>&apos;intrinsic component of postsynaptic specialization membrane&apos; SubClassOf &apos;organelle part&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098892</classIRI>
<classLabel>extrinsic component of postsynaptic specialization membrane</classLabel>
<newAxiom>&apos;extrinsic component of postsynaptic specialization membrane&apos; SubClassOf &apos;organelle part&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098899</classIRI>
<classLabel>spine apparatus lumen</classLabel>
<deletedAxiom>&apos;spine apparatus lumen&apos; SubClassOf &apos;synapse part&apos;</deletedAxiom>
<deletedAxiom>&apos;spine apparatus lumen&apos; SubClassOf &apos;part of&apos; some &apos;synaptic vesicle&apos;</deletedAxiom>
<deletedAxiom>&apos;spine apparatus lumen&apos; SubClassOf &apos;synaptic vesicle lumen&apos;</deletedAxiom>
<newAxiom>&apos;spine apparatus lumen&apos; SubClassOf &apos;cytoplasmic vesicle lumen&apos;</newAxiom>
<newAxiom>&apos;spine apparatus lumen&apos; SubClassOf &apos;synapse part&apos;</newAxiom>
<newAxiom>&apos;spine apparatus lumen&apos; SubClassOf &apos;neuron part&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098839</classIRI>
<classLabel>postsynaptic density membrane</classLabel>
<deletedAxiom>&apos;postsynaptic density membrane&apos; SubClassOf &apos;adjacent to&apos; some &apos;postsynaptic density&apos;</deletedAxiom>
<deletedAxiom>&apos;postsynaptic density membrane&apos; SubClassOf &apos;part of&apos; some &apos;postsynaptic membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;postsynaptic density membrane&apos; SubClassOf &apos;membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;postsynaptic density membrane&apos; EquivalentTo &apos;membrane&apos; and (&apos;part of&apos; some &apos;postsynaptic membrane&apos;) and (&apos;adjacent to&apos; some &apos;postsynaptic density&apos;)</deletedAxiom>
<newAxiom>&apos;postsynaptic density membrane&apos; SubClassOf &apos;part of&apos; some &apos;postsynaptic membrane&apos;</newAxiom>
<newAxiom>&apos;postsynaptic density membrane&apos; SubClassOf &apos;part of&apos; some &apos;postsynaptic density&apos;</newAxiom>
<newAxiom>&apos;postsynaptic density membrane&apos; EquivalentTo &apos;membrane&apos; and (&apos;part of&apos; some &apos;postsynaptic density&apos;) and (&apos;part of&apos; some &apos;postsynaptic membrane&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905709</classIRI>
<classLabel>negative regulation of regulation of membrane permeability</classLabel>
<deletedAxiom>&apos;negative regulation of regulation of membrane permeability&apos; SubClassOf &apos;regulation of biological quality&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of regulation of membrane permeability&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;regulation of membrane permeability&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of regulation of membrane permeability&apos; SubClassOf &apos;negatively regulates&apos; some &apos;regulation of membrane permeability&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of regulation of membrane permeability&apos; SubClassOf &apos;negative regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of regulation of membrane permeability&apos; SubClassOf &apos;regulation of membrane permeability&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015459</classIRI>
<classLabel>potassium channel regulator activity</classLabel>
<newAxiom>&apos;potassium channel regulator activity&apos; SubClassOf &apos;directly regulates&apos; some &apos;potassium channel activity&apos;</newAxiom>
<newAxiom>&apos;potassium channel regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099106</newAxiom>
<newAxiom>&apos;potassium channel regulator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly regulates&apos; some &apos;potassium channel activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904782</classIRI>
<classLabel>negative regulation of NMDA glutamate receptor activity</classLabel>
<deletedAxiom>&apos;negative regulation of NMDA glutamate receptor activity&apos; SubClassOf &apos;negative regulation of ion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of NMDA glutamate receptor activity&apos; SubClassOf &apos;negative regulation of cation channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904783</classIRI>
<classLabel>positive regulation of NMDA glutamate receptor activity</classLabel>
<deletedAxiom>&apos;positive regulation of NMDA glutamate receptor activity&apos; SubClassOf &apos;positive regulation of ion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of NMDA glutamate receptor activity&apos; SubClassOf &apos;positive regulation of cation channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015277</classIRI>
<classLabel>kainate selective glutamate receptor activity</classLabel>
<newAxiom>&apos;kainate selective glutamate receptor activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099094</newAxiom>
<newAxiom>&apos;kainate selective glutamate receptor activity&apos; SubClassOf &apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_29101</newAxiom>
<newAxiom>&apos;kainate selective glutamate receptor activity&apos; SubClassOf &apos;sodium channel activity&apos;</newAxiom>
<newAxiom>&apos;kainate selective glutamate receptor activity&apos; SubClassOf &apos;potassium channel activity&apos;</newAxiom>
<newAxiom>&apos;kainate selective glutamate receptor activity&apos; SubClassOf &apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_29103</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015276</classIRI>
<classLabel>ligand-gated ion channel activity</classLabel>
<deletedAxiom>&apos;ligand-gated ion channel activity&apos; SubClassOf &apos;ion channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;ligand-gated ion channel activity&apos; SubClassOf &apos;transmembrane receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;ligand-gated ion channel activity&apos; SubClassOf &apos;ligand-gated channel activity&apos;</deletedAxiom>
<newAxiom>&apos;ligand-gated ion channel activity&apos; SubClassOf &apos;ion channel activity&apos;</newAxiom>
<newAxiom>&apos;ligand-gated ion channel activity&apos; SubClassOf &apos;ligand-gated channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015280</classIRI>
<classLabel>ligand-gated sodium channel activity</classLabel>
<newAxiom>&apos;ligand-gated sodium channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099094</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030545</classIRI>
<classLabel>receptor regulator activity</classLabel>
<deletedAxiom>&apos;receptor regulator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;regulates&apos; some &apos;receptor activity&apos;)</deletedAxiom>
<newAxiom>&apos;receptor regulator activity&apos; SubClassOf &apos;directly regulates&apos; some &apos;receptor activity&apos;</newAxiom>
<newAxiom>&apos;receptor regulator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly regulates&apos; some &apos;receptor activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030546</classIRI>
<classLabel>receptor activator activity</classLabel>
<newAxiom>&apos;receptor activator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly activates&apos; some &apos;receptor activity&apos;)</newAxiom>
<newAxiom>&apos;receptor activator activity&apos; SubClassOf &apos;directly activates&apos; some &apos;receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030547</classIRI>
<classLabel>receptor inhibitor activity</classLabel>
<newAxiom>&apos;receptor inhibitor activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly inhibits&apos; some &apos;receptor activity&apos;)</newAxiom>
<newAxiom>&apos;receptor inhibitor activity&apos; SubClassOf &apos;directly inhibits&apos; some &apos;receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030549</classIRI>
<classLabel>acetylcholine receptor activator activity</classLabel>
<deletedAxiom>&apos;acetylcholine receptor activator activity&apos; SubClassOf &apos;acetylcholine receptor regulator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;acetylcholine receptor activator activity&apos; SubClassOf &apos;positively regulates&apos; some &apos;acetylcholine receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;acetylcholine receptor activator activity&apos; SubClassOf &apos;receptor activator activity&apos;</deletedAxiom>
<newAxiom>&apos;acetylcholine receptor activator activity&apos; SubClassOf &apos;acetylcholine receptor regulator activity&apos;</newAxiom>
<newAxiom>&apos;acetylcholine receptor activator activity&apos; SubClassOf &apos;directly activates&apos; some &apos;acetylcholine receptor activity&apos;</newAxiom>
<newAxiom>&apos;acetylcholine receptor activator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly activates&apos; some &apos;acetylcholine receptor activity&apos;)</newAxiom>
<newAxiom>&apos;acetylcholine receptor activator activity&apos; SubClassOf &apos;receptor activator activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030550</classIRI>
<classLabel>acetylcholine receptor inhibitor activity</classLabel>
<deletedAxiom>&apos;acetylcholine receptor inhibitor activity&apos; SubClassOf &apos;negatively regulates&apos; some &apos;acetylcholine receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;acetylcholine receptor inhibitor activity&apos; SubClassOf &apos;acetylcholine receptor regulator activity&apos;</deletedAxiom>
<newAxiom>&apos;acetylcholine receptor inhibitor activity&apos; SubClassOf &apos;directly inhibits&apos; some &apos;acetylcholine receptor activity&apos;</newAxiom>
<newAxiom>&apos;acetylcholine receptor inhibitor activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly inhibits&apos; some &apos;acetylcholine receptor activity&apos;)</newAxiom>
<newAxiom>&apos;acetylcholine receptor inhibitor activity&apos; SubClassOf &apos;acetylcholine receptor regulator activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030295</classIRI>
<classLabel>protein kinase activator activity</classLabel>
<deletedAxiom>&apos;protein kinase activator activity&apos; SubClassOf &apos;kinase activator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;protein kinase activator activity&apos; SubClassOf &apos;positively regulates&apos; some &apos;protein kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;protein kinase activator activity&apos; SubClassOf &apos;protein kinase regulator activity&apos;</deletedAxiom>
<newAxiom>&apos;protein kinase activator activity&apos; SubClassOf &apos;kinase activator activity&apos;</newAxiom>
<newAxiom>&apos;protein kinase activator activity&apos; SubClassOf &apos;directly activates&apos; some &apos;protein kinase activity&apos;</newAxiom>
<newAxiom>&apos;protein kinase activator activity&apos; SubClassOf &apos;protein kinase regulator activity&apos;</newAxiom>
<newAxiom>&apos;protein kinase activator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly activates&apos; some &apos;protein kinase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030296</classIRI>
<classLabel>protein tyrosine kinase activator activity</classLabel>
<newAxiom>&apos;protein tyrosine kinase activator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly activates&apos; some &apos;protein tyrosine kinase activity&apos;)</newAxiom>
<newAxiom>&apos;protein tyrosine kinase activator activity&apos; SubClassOf &apos;directly activates&apos; some &apos;protein tyrosine kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030297</classIRI>
<classLabel>transmembrane receptor protein tyrosine kinase activator activity</classLabel>
<deletedAxiom>&apos;transmembrane receptor protein tyrosine kinase activator activity&apos; SubClassOf &apos;positively regulates&apos; some &apos;transmembrane receptor protein tyrosine kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;transmembrane receptor protein tyrosine kinase activator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly activates&apos; some &apos;transmembrane receptor protein tyrosine kinase activity&apos;)</newAxiom>
<newAxiom>&apos;transmembrane receptor protein tyrosine kinase activator activity&apos; SubClassOf &apos;directly activates&apos; some &apos;transmembrane receptor protein tyrosine kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005224</classIRI>
<classLabel>ATP-binding and phosphorylation-dependent chloride channel activity</classLabel>
<newAxiom>&apos;ATP-binding and phosphorylation-dependent chloride channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099095</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019870</classIRI>
<classLabel>potassium channel inhibitor activity</classLabel>
<newAxiom>&apos;potassium channel inhibitor activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly inhibits&apos; some &apos;potassium channel activity&apos;)</newAxiom>
<newAxiom>&apos;potassium channel inhibitor activity&apos; SubClassOf &apos;directly inhibits&apos; some &apos;potassium channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019887</classIRI>
<classLabel>protein kinase regulator activity</classLabel>
<newAxiom>&apos;protein kinase regulator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly regulates&apos; some &apos;protein kinase activity&apos;)</newAxiom>
<newAxiom>&apos;protein kinase regulator activity&apos; SubClassOf &apos;directly regulates&apos; some &apos;protein kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019888</classIRI>
<classLabel>protein phosphatase regulator activity</classLabel>
<deletedAxiom>&apos;protein phosphatase regulator activity&apos; SubClassOf &apos;phosphatase regulator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;protein phosphatase regulator activity&apos; SubClassOf &apos;regulates&apos; some &apos;phosphoprotein phosphatase activity&apos;</deletedAxiom>
<newAxiom>&apos;protein phosphatase regulator activity&apos; SubClassOf &apos;directly regulates&apos; some &apos;phosphoprotein phosphatase activity&apos;</newAxiom>
<newAxiom>&apos;protein phosphatase regulator activity&apos; SubClassOf &apos;phosphatase regulator activity&apos;</newAxiom>
<newAxiom>&apos;protein phosphatase regulator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly regulates&apos; some &apos;phosphoprotein phosphatase activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005242</classIRI>
<classLabel>inward rectifier potassium channel activity</classLabel>
<newAxiom>&apos;inward rectifier potassium channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099094</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005246</classIRI>
<classLabel>calcium channel regulator activity</classLabel>
<deletedAxiom>&apos;calcium channel regulator activity&apos; SubClassOf &apos;channel regulator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;calcium channel regulator activity&apos; SubClassOf &apos;regulates&apos; some &apos;calcium channel activity&apos;</deletedAxiom>
<newAxiom>&apos;calcium channel regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099106</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030234</classIRI>
<classLabel>enzyme regulator activity</classLabel>
<newAxiom>&apos;enzyme regulator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly regulates&apos; some &apos;catalytic activity&apos;)</newAxiom>
<newAxiom>&apos;enzyme regulator activity&apos; SubClassOf &apos;directly regulates&apos; some &apos;catalytic activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071884</classIRI>
<classLabel>vitamin D receptor activator activity</classLabel>
<newAxiom>&apos;vitamin D receptor activator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly activates&apos; some &apos;calcitriol receptor activity&apos;)</newAxiom>
<newAxiom>&apos;vitamin D receptor activator activity&apos; SubClassOf &apos;directly activates&apos; some &apos;calcitriol receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022852</classIRI>
<classLabel>glycine-gated chloride ion channel activity</classLabel>
<newAxiom>&apos;glycine-gated chloride ion channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099095</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022851</classIRI>
<classLabel>GABA-gated chloride ion channel activity</classLabel>
<newAxiom>&apos;GABA-gated chloride ion channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099095</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007165</classIRI>
<classLabel>signal transduction</classLabel>
<newAxiom>&apos;signal transduction&apos; SubClassOf &apos;cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007186</classIRI>
<classLabel>G-protein coupled receptor signaling pathway</classLabel>
<deletedAxiom>&apos;G-protein coupled receptor signaling pathway&apos; SubClassOf &apos;signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;G-protein coupled receptor signaling pathway&apos; SubClassOf &apos;signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032127</classIRI>
<classLabel>dense core granule membrane</classLabel>
<deletedAxiom>&apos;dense core granule membrane&apos; SubClassOf &apos;secretory granule membrane&apos;</deletedAxiom>
<newAxiom>&apos;dense core granule membrane&apos; SubClassOf &apos;secretory granule membrane&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099628</classIRI>
<classLabel>neurotransmitter receptor diffusion trapping</classLabel>
<deletedAxiom>&apos;neurotransmitter receptor diffusion trapping&apos; SubClassOf &apos;part of&apos; some &apos;neurotransmitter receptor cycle&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099634</classIRI>
<classLabel>postsynaptic specialization membrane</classLabel>
<deletedAxiom>&apos;postsynaptic specialization membrane&apos; SubClassOf &apos;part of&apos; some &apos;postsynaptic membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;postsynaptic specialization membrane&apos; SubClassOf &apos;membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;postsynaptic specialization membrane&apos; EquivalentTo &apos;membrane&apos; and (&apos;part of&apos; some &apos;postsynaptic membrane&apos;) and (&apos;adjacent to&apos; some &apos;postsynaptic specialization&apos;)</deletedAxiom>
<deletedAxiom>&apos;postsynaptic specialization membrane&apos; SubClassOf &apos;adjacent to&apos; some &apos;postsynaptic specialization&apos;</deletedAxiom>
<newAxiom>&apos;postsynaptic specialization membrane&apos; SubClassOf &apos;organelle part&apos;</newAxiom>
<newAxiom>&apos;postsynaptic specialization membrane&apos; SubClassOf &apos;part of&apos; some &apos;postsynaptic membrane&apos;</newAxiom>
<newAxiom>&apos;postsynaptic specialization membrane&apos; EquivalentTo &apos;membrane&apos; and (&apos;part of&apos; some &apos;postsynaptic membrane&apos;) and (&apos;part of&apos; some &apos;postsynaptic specialization&apos;)</newAxiom>
<newAxiom>&apos;postsynaptic specialization membrane&apos; SubClassOf &apos;part of&apos; some &apos;postsynaptic specialization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099633</classIRI>
<classLabel>protein localization to postsynaptic specialization membrane</classLabel>
<newAxiom>&apos;protein localization to postsynaptic specialization membrane&apos; SubClassOf &apos;protein localization to organelle&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099639</classIRI>
<classLabel>neurotransmitter receptor transport, endosome to plasma membrane</classLabel>
<deletedAxiom>&apos;neurotransmitter receptor transport, endosome to plasma membrane&apos; SubClassOf &apos;part of&apos; some &apos;neurotransmitter receptor cycle&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099646</classIRI>
<classLabel>neurotransmitter receptor transport, plasma membrane to endosome</classLabel>
<deletedAxiom>&apos;neurotransmitter receptor transport, plasma membrane to endosome&apos; SubClassOf &apos;part of&apos; some &apos;neurotransmitter receptor cycle&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099604</classIRI>
<classLabel>ligand-gated calcium channel activity</classLabel>
<deletedAxiom>&apos;ligand-gated calcium channel activity&apos; SubClassOf &apos;ligand-gated ion channel activity&apos;</deletedAxiom>
<newAxiom>&apos;ligand-gated calcium channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099094</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099588</classIRI>
<classLabel>positive regulation of postsynaptic cytosolic calcium concentration</classLabel>
<newAxiom>&apos;positive regulation of postsynaptic cytosolic calcium concentration&apos; SubClassOf &apos;regulation of postsynaptic cytosolic calcium ion concentration&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099590</classIRI>
<classLabel>neurotransmitter receptor internalization</classLabel>
<deletedAxiom>&apos;neurotransmitter receptor internalization&apos; SubClassOf &apos;part of&apos; some &apos;neurotransmitter receptor cycle&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099566</classIRI>
<classLabel>regulation of postsynaptic cytosolic calcium ion concentration</classLabel>
<deletedAxiom>&apos;regulation of postsynaptic cytosolic calcium ion concentration&apos; SubClassOf &apos;regulation of cytosolic calcium ion concentration&apos;</deletedAxiom>
<newAxiom>&apos;regulation of postsynaptic cytosolic calcium ion concentration&apos; EquivalentTo &apos;regulation of cytosolic calcium ion concentration&apos; and (&apos;occurs in&apos; some &apos;postsynapse&apos;)</newAxiom>
<newAxiom>&apos;regulation of postsynaptic cytosolic calcium ion concentration&apos; SubClassOf &apos;occurs in&apos; some &apos;postsynapse&apos;</newAxiom>
<newAxiom>&apos;regulation of postsynaptic cytosolic calcium ion concentration&apos; SubClassOf &apos;regulation of cytosolic calcium ion concentration&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099572</classIRI>
<classLabel>postsynaptic specialization</classLabel>
<deletedAxiom>&apos;postsynaptic specialization&apos; SubClassOf &apos;intracellular non-membrane-bounded organelle&apos;</deletedAxiom>
<deletedAxiom>&apos;postsynaptic specialization&apos; SubClassOf &apos;adjacent to&apos; some &apos;postsynaptic membrane&apos;</deletedAxiom>
<newAxiom>&apos;postsynaptic specialization&apos; SubClassOf &apos;cell part&apos;</newAxiom>
<newAxiom>&apos;postsynaptic specialization&apos; SubClassOf &apos;organelle&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016934</classIRI>
<classLabel>extracellular-glycine-gated chloride channel activity</classLabel>
<newAxiom>&apos;extracellular-glycine-gated chloride channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099095</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002162</classIRI>
<classLabel>dystroglycan binding</classLabel>
<deletedAxiom>&apos;dystroglycan binding&apos; SubClassOf &apos;protein binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099012</classIRI>
<classLabel>neuronal dense core vesicle membrane</classLabel>
<deletedAxiom>&apos;neuronal dense core vesicle membrane&apos; SubClassOf &apos;part of&apos; some &apos;dense core granule&apos;</deletedAxiom>
<deletedAxiom>&apos;neuronal dense core vesicle membrane&apos; SubClassOf &apos;secretory granule membrane&apos;</deletedAxiom>
<newAxiom>&apos;neuronal dense core vesicle membrane&apos; SubClassOf &apos;part of&apos; some &apos;neuronal dense core vesicle&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016557</classIRI>
<classLabel>peroxisome membrane biogenesis</classLabel>
<deletedAxiom>&apos;peroxisome membrane biogenesis&apos; SubClassOf &apos;membrane biogenesis&apos;</deletedAxiom>
<newAxiom>&apos;peroxisome membrane biogenesis&apos; SubClassOf &apos;membrane biogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903822</classIRI>
<classLabel>signal transduction involved in morphogenesis checkpoint</classLabel>
<newAxiom>&apos;signal transduction involved in morphogenesis checkpoint&apos; SubClassOf &apos;mitotic cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016248</classIRI>
<classLabel>channel inhibitor activity</classLabel>
<newAxiom>&apos;channel inhibitor activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly inhibits&apos; some &apos;channel activity&apos;)</newAxiom>
<newAxiom>&apos;channel inhibitor activity&apos; SubClassOf &apos;directly inhibits&apos; some &apos;channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008200</classIRI>
<classLabel>ion channel inhibitor activity</classLabel>
<deletedAxiom>&apos;ion channel inhibitor activity&apos; SubClassOf &apos;channel inhibitor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;ion channel inhibitor activity&apos; SubClassOf &apos;negatively regulates&apos; some &apos;ion channel activity&apos;</deletedAxiom>
<newAxiom>&apos;ion channel inhibitor activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly inhibits&apos; some &apos;ion channel activity&apos;)</newAxiom>
<newAxiom>&apos;ion channel inhibitor activity&apos; SubClassOf &apos;channel inhibitor activity&apos;</newAxiom>
<newAxiom>&apos;ion channel inhibitor activity&apos; SubClassOf &apos;directly inhibits&apos; some &apos;ion channel activity&apos;</newAxiom>
<newAxiom>&apos;ion channel inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099106</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008047</classIRI>
<classLabel>enzyme activator activity</classLabel>
<newAxiom>&apos;enzyme activator activity&apos; SubClassOf &apos;directly activates&apos; some &apos;catalytic activity&apos;</newAxiom>
<newAxiom>&apos;enzyme activator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly activates&apos; some &apos;catalytic activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008068</classIRI>
<classLabel>extracellular-glutamate-gated chloride channel activity</classLabel>
<newAxiom>&apos;extracellular-glutamate-gated chloride channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099095</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072684</classIRI>
<classLabel>mitochondrial tRNA 3&apos;-trailer cleavage, endonucleolytic</classLabel>
<deletedAxiom>&apos;mitochondrial tRNA 3&apos;-trailer cleavage, endonucleolytic&apos; SubClassOf &apos;mitochondrial tRNA 3&apos;-end processing&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial tRNA 3&apos;-trailer cleavage, endonucleolytic&apos; SubClassOf &apos;mitochondrial RNA metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072542</classIRI>
<classLabel>protein phosphatase activator activity</classLabel>
<deletedAxiom>&apos;protein phosphatase activator activity&apos; SubClassOf &apos;phosphatase activator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;protein phosphatase activator activity&apos; SubClassOf &apos;protein phosphatase regulator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;protein phosphatase activator activity&apos; SubClassOf &apos;positively regulates&apos; some &apos;phosphoprotein phosphatase activity&apos;</deletedAxiom>
<newAxiom>&apos;protein phosphatase activator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly activates&apos; some &apos;phosphoprotein phosphatase activity&apos;)</newAxiom>
<newAxiom>&apos;protein phosphatase activator activity&apos; SubClassOf &apos;phosphatase activator activity&apos;</newAxiom>
<newAxiom>&apos;protein phosphatase activator activity&apos; SubClassOf &apos;directly activates&apos; some &apos;phosphoprotein phosphatase activity&apos;</newAxiom>
<newAxiom>&apos;protein phosphatase activator activity&apos; SubClassOf &apos;protein phosphatase regulator activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072411</classIRI>
<classLabel>signal transduction involved in meiotic cell cycle checkpoint</classLabel>
<deletedAxiom>&apos;signal transduction involved in meiotic cell cycle checkpoint&apos; SubClassOf &apos;reproductive process&apos;</deletedAxiom>
<newAxiom>&apos;signal transduction involved in meiotic cell cycle checkpoint&apos; SubClassOf &apos;meiotic cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072413</classIRI>
<classLabel>signal transduction involved in mitotic cell cycle checkpoint</classLabel>
<newAxiom>&apos;signal transduction involved in mitotic cell cycle checkpoint&apos; SubClassOf &apos;mitotic cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072101</classIRI>
<classLabel>specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway</classLabel>
<newAxiom>&apos;specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway&apos; SubClassOf &apos;single-organism cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052194</classIRI>
<classLabel>movement on or near symbiont</classLabel>
<deletedAxiom>&apos;movement on or near symbiont&apos; SubClassOf &apos;movement on or near other organism involved in symbiotic interaction&apos;</deletedAxiom>
<deletedAxiom>&apos;movement on or near symbiont&apos; SubClassOf &apos;movement in symbiont environment&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052193</classIRI>
<classLabel>movement in symbiont environment</classLabel>
<deletedAxiom>&apos;movement in symbiont environment&apos; SubClassOf &apos;movement in environment of other organism involved in symbiotic interaction&apos;</deletedAxiom>
<deletedAxiom>&apos;movement in symbiont environment&apos; SubClassOf &apos;interaction with symbiont&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902420</classIRI>
<classLabel>signal transduction involved in Dma1-dependent checkpoint</classLabel>
<newAxiom>&apos;signal transduction involved in Dma1-dependent checkpoint&apos; SubClassOf &apos;mitotic cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902402</classIRI>
<classLabel>signal transduction involved in mitotic DNA damage checkpoint</classLabel>
<deletedAxiom>&apos;signal transduction involved in mitotic DNA damage checkpoint&apos; SubClassOf &apos;mitotic cell cycle process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042779</classIRI>
<classLabel>tRNA 3&apos;-trailer cleavage</classLabel>
<deletedAxiom>&apos;tRNA 3&apos;-trailer cleavage&apos; SubClassOf &apos;tRNA 3&apos;-end processing&apos;</deletedAxiom>
<newAxiom>&apos;tRNA 3&apos;-trailer cleavage&apos; SubClassOf &apos;part of&apos; some &apos;tRNA 3&apos;-end processing&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042699</classIRI>
<classLabel>follicle-stimulating hormone signaling pathway</classLabel>
<newAxiom>&apos;follicle-stimulating hormone signaling pathway&apos; SubClassOf &apos;cellular process involved in reproduction in multicellular organism&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032983</classIRI>
<classLabel>kainate selective glutamate receptor complex</classLabel>
<newAxiom>&apos;kainate selective glutamate receptor complex&apos; SubClassOf &apos;potassium channel complex&apos;</newAxiom>
<newAxiom>&apos;kainate selective glutamate receptor complex&apos; SubClassOf &apos;sodium channel complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017146</classIRI>
<classLabel>NMDA selective glutamate receptor complex</classLabel>
<newAxiom>&apos;NMDA selective glutamate receptor complex&apos; SubClassOf &apos;cation channel complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017020</classIRI>
<classLabel>myosin phosphatase regulator activity</classLabel>
<deletedAxiom>&apos;myosin phosphatase regulator activity&apos; SubClassOf &apos;phosphatase regulator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;myosin phosphatase regulator activity&apos; SubClassOf &apos;regulates&apos; some &apos;myosin phosphatase activity&apos;</deletedAxiom>
<newAxiom>&apos;myosin phosphatase regulator activity&apos; SubClassOf &apos;directly regulates&apos; some &apos;myosin phosphatase activity&apos;</newAxiom>
<newAxiom>&apos;myosin phosphatase regulator activity&apos; SubClassOf &apos;protein phosphatase regulator activity&apos;</newAxiom>
<newAxiom>&apos;myosin phosphatase regulator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly regulates&apos; some &apos;myosin phosphatase activity&apos;)</newAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_Union_0000031</classIRI>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905711</classIRI>
<classLabel>response to phosphatidylethanolamine</classLabel>
<newAxiom>'response to phosphatidylethanolamine' EquivalentTo 'response to stimulus' and ('has input' some http://purl.obolibrary.org/obo/CHEBI_16038)</newAxiom>
<newAxiom>'response to phosphatidylethanolamine' SubClassOf 'has input' some http://purl.obolibrary.org/obo/CHEBI_16038</newAxiom>
<newAxiom>'response to phosphatidylethanolamine' SubClassOf 'response to oxygen-containing compound'</newAxiom>
<newAxiom>'response to phosphatidylethanolamine' SubClassOf 'response to organophosphorus'</newAxiom>
<newAxiom>'response to phosphatidylethanolamine' SubClassOf 'response to lipid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905712</classIRI>
<classLabel>cellular response to phosphatidylethanolamine</classLabel>
<newAxiom>'cellular response to phosphatidylethanolamine' EquivalentTo 'cellular response to chemical stimulus' and ('has input' some http://purl.obolibrary.org/obo/CHEBI_16038)</newAxiom>
<newAxiom>'cellular response to phosphatidylethanolamine' SubClassOf 'cellular response to oxygen-containing compound'</newAxiom>
<newAxiom>'cellular response to phosphatidylethanolamine' SubClassOf 'response to phosphatidylethanolamine'</newAxiom>
<newAxiom>'cellular response to phosphatidylethanolamine' SubClassOf 'has input' some http://purl.obolibrary.org/obo/CHEBI_16038</newAxiom>
<newAxiom>'cellular response to phosphatidylethanolamine' SubClassOf 'cellular response to lipid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099100</classIRI>
<classLabel>G-protein gated cation channel activity</classLabel>
<newAxiom>'G-protein gated cation channel activity' SubClassOf 'regulated by' some 'G-protein beta/gamma-subunit complex binding'</newAxiom>
<newAxiom>'G-protein gated cation channel activity' EquivalentTo 'gated channel activity' and ('transports or maintains localization of' some http://purl.obolibrary.org/obo/CHEBI_36915) and ('regulated by' some 'G-protein beta/gamma-subunit complex binding')</newAxiom>
<newAxiom>'G-protein gated cation channel activity' SubClassOf 'cation channel activity'</newAxiom>
<newAxiom>'G-protein gated cation channel activity' SubClassOf 'G-protein gated ion channel activity'</newAxiom>
<newAxiom>'G-protein gated cation channel activity' SubClassOf 'transports or maintains localization of' some http://purl.obolibrary.org/obo/CHEBI_36915</newAxiom>
<newAxiom>'G-protein gated cation channel activity' SubClassOf 'inorganic cation transmembrane transporter activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099102</classIRI>
<classLabel>G-protein gated potassium channel activity involved in regulation of postsynaptic membrane potential</classLabel>
<newAxiom>'G-protein gated potassium channel activity involved in regulation of postsynaptic membrane potential' EquivalentTo 'G-protein gated potassium channel activity' and ('part of' some 'regulation of postsynaptic membrane potential')</newAxiom>
<newAxiom>'G-protein gated potassium channel activity involved in regulation of postsynaptic membrane potential' SubClassOf 'part of' some 'regulation of postsynaptic membrane potential'</newAxiom>
<newAxiom>'G-protein gated potassium channel activity involved in regulation of postsynaptic membrane potential' SubClassOf 'G-protein gated potassium channel activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099101</classIRI>
<classLabel>G-protein gated potassium channel activity</classLabel>
<newAxiom>'G-protein gated potassium channel activity' SubClassOf 'potassium channel activity'</newAxiom>
<newAxiom>'G-protein gated potassium channel activity' EquivalentTo 'gated channel activity' and ('transports or maintains localization of' some http://purl.obolibrary.org/obo/CHEBI_29103) and ('regulated by' some 'G-protein beta/gamma-subunit complex binding')</newAxiom>
<newAxiom>'G-protein gated potassium channel activity' SubClassOf 'G-protein gated cation channel activity'</newAxiom>
<newAxiom>'G-protein gated potassium channel activity' SubClassOf 'transports or maintains localization of' some http://purl.obolibrary.org/obo/CHEBI_29103</newAxiom>
<newAxiom>'G-protein gated potassium channel activity' SubClassOf 'regulated by' some 'G-protein beta/gamma-subunit complex binding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099104</classIRI>
<classLabel>potassium channel activator activity</classLabel>
<newAxiom>'potassium channel activator activity' EquivalentTo 'molecular_function' and ('directly activates' some 'potassium channel activity')</newAxiom>
<newAxiom>'potassium channel activator activity' SubClassOf 'directly activates' some 'potassium channel activity'</newAxiom>
<newAxiom>'potassium channel activator activity' SubClassOf 'channel activator activity'</newAxiom>
<newAxiom>'potassium channel activator activity' SubClassOf 'potassium channel regulator activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099103</classIRI>
<classLabel>channel activator activity</classLabel>
<newAxiom>'channel activator activity' SubClassOf 'channel regulator activity'</newAxiom>
<newAxiom>'channel activator activity' SubClassOf 'directly activates' some 'channel activity'</newAxiom>
<newAxiom>'channel activator activity' EquivalentTo 'molecular_function' and ('directly activates' some 'channel activity')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099106</classIRI>
<classLabel>ion channel regulator activity</classLabel>
<newAxiom>'ion channel regulator activity' SubClassOf 'directly regulates' some 'ion channel activity'</newAxiom>
<newAxiom>'ion channel regulator activity' EquivalentTo 'molecular_function' and ('directly regulates' some 'ion channel activity')</newAxiom>
<newAxiom>'ion channel regulator activity' SubClassOf 'channel regulator activity'</newAxiom>
<newAxiom>'ion channel regulator activity' SubClassOf 'regulates' some 'channel activity'</newAxiom>
<newAxiom>'ion channel regulator activity' SubClassOf 'molecular_function'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099105</classIRI>
<classLabel>ion channel modulating, G-protein coupled receptor signaling pathway</classLabel>
<newAxiom>'ion channel modulating, G-protein coupled receptor signaling pathway' SubClassOf 'has_part' some 'ion channel regulator activity'</newAxiom>
<newAxiom>'ion channel modulating, G-protein coupled receptor signaling pathway' EquivalentTo 'G-protein coupled receptor signaling pathway' and ('has_part' some 'ion channel activity') and ('has_part' some 'ion channel regulator activity')</newAxiom>
<newAxiom>'ion channel modulating, G-protein coupled receptor signaling pathway' SubClassOf 'G-protein coupled receptor signaling pathway'</newAxiom>
<newAxiom>'ion channel modulating, G-protein coupled receptor signaling pathway' SubClassOf 'has_part' some 'ion channel activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099108</classIRI>
<classLabel>potassium channel activator activity involved in G-protein coupled receptor signaling pathway</classLabel>
<newAxiom>'potassium channel activator activity involved in G-protein coupled receptor signaling pathway' SubClassOf 'part of' some 'potassium channel activating, G-protein coupled receptor signaling pathway'</newAxiom>
<newAxiom>'potassium channel activator activity involved in G-protein coupled receptor signaling pathway' SubClassOf 'potassium channel activator activity'</newAxiom>
<newAxiom>'potassium channel activator activity involved in G-protein coupled receptor signaling pathway' SubClassOf 'part of' some 'G-protein coupled receptor signaling pathway'</newAxiom>
<newAxiom>'potassium channel activator activity involved in G-protein coupled receptor signaling pathway' SubClassOf 'ion channel regulator activity involved in G-protein coupled receptor signaling pathway'</newAxiom>
<newAxiom>'potassium channel activator activity involved in G-protein coupled receptor signaling pathway' EquivalentTo 'potassium channel activator activity' and ('part of' some 'G-protein coupled receptor signaling pathway')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099107</classIRI>
<classLabel>ion channel regulator activity involved in G-protein coupled receptor signaling pathway</classLabel>
<newAxiom>'ion channel regulator activity involved in G-protein coupled receptor signaling pathway' SubClassOf 'ion channel regulator activity'</newAxiom>
<newAxiom>'ion channel regulator activity involved in G-protein coupled receptor signaling pathway' SubClassOf 'part of' some 'G-protein coupled receptor signaling pathway'</newAxiom>
<newAxiom>'ion channel regulator activity involved in G-protein coupled receptor signaling pathway' SubClassOf 'signal transducer activity'</newAxiom>
<newAxiom>'ion channel regulator activity involved in G-protein coupled receptor signaling pathway' EquivalentTo 'ion channel regulator activity' and ('part of' some 'G-protein coupled receptor signaling pathway')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099109</classIRI>
<classLabel>potassium channel activating, G-protein coupled receptor signaling pathway</classLabel>
<newAxiom>'potassium channel activating, G-protein coupled receptor signaling pathway' SubClassOf 'has_part' some 'potassium channel activator activity'</newAxiom>
<newAxiom>'potassium channel activating, G-protein coupled receptor signaling pathway' EquivalentTo 'G-protein coupled receptor signaling pathway' and ('has_part' some 'potassium channel activity') and ('has_part' some 'potassium channel activator activity')</newAxiom>
<newAxiom>'potassium channel activating, G-protein coupled receptor signaling pathway' SubClassOf 'ion channel modulating, G-protein coupled receptor signaling pathway'</newAxiom>
<newAxiom>'potassium channel activating, G-protein coupled receptor signaling pathway' SubClassOf 'has_part' some 'potassium channel activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099092</classIRI>
<classLabel>postsynaptic density, intracellular component</classLabel>
<newAxiom>'postsynaptic density, intracellular component' SubClassOf 'synapse part'</newAxiom>
<newAxiom>'postsynaptic density, intracellular component' SubClassOf 'part of' some 'postsynaptic density'</newAxiom>
<newAxiom>'postsynaptic density, intracellular component' SubClassOf 'non-membrane-bounded organelle'</newAxiom>
<newAxiom>'postsynaptic density, intracellular component' SubClassOf 'organelle part'</newAxiom>
<newAxiom>'postsynaptic density, intracellular component' SubClassOf 'cell part'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099091</classIRI>
<classLabel>postsynaptic specialization, intracellular component</classLabel>
<newAxiom>'postsynaptic specialization, intracellular component' SubClassOf 'non-membrane-bounded organelle'</newAxiom>
<newAxiom>'postsynaptic specialization, intracellular component' SubClassOf 'organelle part'</newAxiom>
<newAxiom>'postsynaptic specialization, intracellular component' SubClassOf 'cell part'</newAxiom>
<newAxiom>'postsynaptic specialization, intracellular component' SubClassOf 'part of' some 'postsynaptic specialization'</newAxiom>
<newAxiom>'postsynaptic specialization, intracellular component' SubClassOf 'synapse part'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099094</classIRI>
<classLabel>ligand-gated cation channel activity</classLabel>
<newAxiom>'ligand-gated cation channel activity' SubClassOf 'ligand-gated ion channel activity'</newAxiom>
<newAxiom>'ligand-gated cation channel activity' EquivalentTo 'ligand-gated channel activity' and ('transports or maintains localization of' some http://purl.obolibrary.org/obo/CHEBI_36915)</newAxiom>
<newAxiom>'ligand-gated cation channel activity' SubClassOf 'transports or maintains localization of' some http://purl.obolibrary.org/obo/CHEBI_36915</newAxiom>
<newAxiom>'ligand-gated cation channel activity' SubClassOf 'cation channel activity'</newAxiom>
<newAxiom>'ligand-gated cation channel activity' SubClassOf 'inorganic cation transmembrane transporter activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099096</classIRI>
<classLabel>vestibular calyx terminal</classLabel>
<newAxiom>'vestibular calyx terminal' SubClassOf 'axon terminus'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099095</classIRI>
<classLabel>ligand-gated anion channel activity</classLabel>
<newAxiom>'ligand-gated anion channel activity' SubClassOf 'ligand-gated ion channel activity'</newAxiom>
<newAxiom>'ligand-gated anion channel activity' SubClassOf 'transports or maintains localization of' some http://purl.obolibrary.org/obo/CHEBI_24834</newAxiom>
<newAxiom>'ligand-gated anion channel activity' EquivalentTo 'ligand-gated channel activity' and ('transports or maintains localization of' some http://purl.obolibrary.org/obo/CHEBI_24834)</newAxiom>
<newAxiom>'ligand-gated anion channel activity' SubClassOf 'anion channel activity'</newAxiom>
<newAxiom>'ligand-gated anion channel activity' SubClassOf 'inorganic anion transmembrane transporter activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099097</classIRI>
<classLabel>prospore membrane biogenesis</classLabel>
<newAxiom>'prospore membrane biogenesis' EquivalentTo 'cellular component biogenesis' and ('has output' some 'prospore membrane')</newAxiom>
<newAxiom>'prospore membrane biogenesis' SubClassOf 'has output' some 'prospore membrane'</newAxiom>
<newAxiom>'prospore membrane biogenesis' SubClassOf 'membrane biogenesis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099099</classIRI>
<classLabel>G-protein gated ion channel activity</classLabel>
<newAxiom>'G-protein gated ion channel activity' SubClassOf 'transports or maintains localization of' some http://purl.obolibrary.org/obo/CHEBI_24870</newAxiom>
<newAxiom>'G-protein gated ion channel activity' EquivalentTo 'gated channel activity' and ('transports or maintains localization of' some http://purl.obolibrary.org/obo/CHEBI_24870) and ('regulated by' some 'G-protein beta/gamma-subunit complex binding')</newAxiom>
<newAxiom>'G-protein gated ion channel activity' SubClassOf 'regulated by' some 'G-protein beta/gamma-subunit complex binding'</newAxiom>
<newAxiom>'G-protein gated ion channel activity' SubClassOf 'gated channel activity'</newAxiom>
<newAxiom>'G-protein gated ion channel activity' SubClassOf 'ion channel activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990985</classIRI>
<classLabel>obsolete apoptosis in response to oxidative stress</classLabel>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>