<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
67
</numberChangedClasses>
<numberNewClasses>
22
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010524</classIRI>
<classLabel>positive regulation of calcium ion transport into cytosol</classLabel>
<newAxiom>&apos;positive regulation of calcium ion transport into cytosol&apos; SubClassOf &apos;positive regulation of cytosolic calcium ion concentration&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010536</classIRI>
<classLabel>positive regulation of activation of Janus kinase activity</classLabel>
<newAxiom>&apos;positive regulation of activation of Janus kinase activity&apos; SubClassOf &apos;positive regulation of protein kinase activity&apos;</newAxiom>
<newAxiom>&apos;positive regulation of activation of Janus kinase activity&apos; SubClassOf &apos;positive regulation of JAK-STAT cascade&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034123</classIRI>
<classLabel>positive regulation of toll-like receptor signaling pathway</classLabel>
<deletedAxiom>&apos;positive regulation of toll-like receptor signaling pathway&apos; SubClassOf &apos;positive regulation of immune system process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of toll-like receptor signaling pathway&apos; SubClassOf &apos;positive regulation of innate immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000640</classIRI>
<classLabel>positive regulation of SREBP signaling pathway</classLabel>
<newAxiom>&apos;positive regulation of SREBP signaling pathway&apos; SubClassOf &apos;positive regulation of transcription from RNA polymerase II promoter&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000198</classIRI>
<classLabel>activation of MAPKK activity involved in cell wall organization or biogenesis</classLabel>
<deletedAxiom>&apos;activation of MAPKK activity involved in cell wall organization or biogenesis&apos; SubClassOf &apos;positive regulation of MAPK cascade involved in cell wall organization or biogenesis&apos;</deletedAxiom>
<newAxiom>&apos;activation of MAPKK activity involved in cell wall organization or biogenesis&apos; SubClassOf &apos;activation of MAPK activity involved in cell wall organization or biogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000197</classIRI>
<classLabel>activation of MAPKKK activity involved in cell wall organization or biogenesis</classLabel>
<deletedAxiom>&apos;activation of MAPKKK activity involved in cell wall organization or biogenesis&apos; SubClassOf &apos;positive regulation of MAPK cascade involved in cell wall organization or biogenesis&apos;</deletedAxiom>
<newAxiom>&apos;activation of MAPKKK activity involved in cell wall organization or biogenesis&apos; SubClassOf &apos;activation of MAPKK activity involved in cell wall organization or biogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000185</classIRI>
<classLabel>activation of MAPKKK activity</classLabel>
<deletedAxiom>&apos;activation of MAPKKK activity&apos; SubClassOf &apos;positive regulation of MAPK cascade&apos;</deletedAxiom>
<deletedAxiom>&apos;activation of MAPKKK activity&apos; SubClassOf &apos;positive regulation of protein serine/threonine kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;activation of MAPKKK activity&apos; SubClassOf &apos;regulation of MAP kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;activation of MAPKKK activity&apos; SubClassOf &apos;positive regulation of MAP kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000186</classIRI>
<classLabel>activation of MAPKK activity</classLabel>
<deletedAxiom>&apos;activation of MAPKK activity&apos; SubClassOf &apos;positive regulation of MAPK cascade&apos;</deletedAxiom>
<deletedAxiom>&apos;activation of MAPKK activity&apos; SubClassOf &apos;regulation of MAP kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;activation of MAPKK activity&apos; SubClassOf &apos;positive regulation of MAP kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000167</classIRI>
<classLabel>activation of MAPKKK activity involved in osmosensory signaling pathway</classLabel>
<deletedAxiom>&apos;activation of MAPKKK activity involved in osmosensory signaling pathway&apos; SubClassOf &apos;regulation of response to osmotic stress&apos;</deletedAxiom>
<deletedAxiom>&apos;activation of MAPKKK activity involved in osmosensory signaling pathway&apos; SubClassOf &apos;regulation of cellular response to stress&apos;</deletedAxiom>
<newAxiom>&apos;activation of MAPKKK activity involved in osmosensory signaling pathway&apos; SubClassOf &apos;activation of MAPKK activity involved in osmosensory signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000168</classIRI>
<classLabel>activation of MAPKK activity involved in osmosensory signaling pathway</classLabel>
<deletedAxiom>&apos;activation of MAPKK activity involved in osmosensory signaling pathway&apos; SubClassOf &apos;regulation of response to osmotic stress&apos;</deletedAxiom>
<deletedAxiom>&apos;activation of MAPKK activity involved in osmosensory signaling pathway&apos; SubClassOf &apos;regulation of cellular response to stress&apos;</deletedAxiom>
<newAxiom>&apos;activation of MAPKK activity involved in osmosensory signaling pathway&apos; SubClassOf &apos;activation of MAPK activity involved in osmosensory signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000525</classIRI>
<classLabel>positive regulation of T cell costimulation</classLabel>
<deletedAxiom>&apos;positive regulation of T cell costimulation&apos; SubClassOf &apos;positive regulation of immune system process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of T cell costimulation&apos; SubClassOf &apos;positive regulation of T cell activation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000813</classIRI>
<classLabel>negative regulation of barbed-end actin filament capping</classLabel>
<deletedAxiom>&apos;negative regulation of barbed-end actin filament capping&apos; SubClassOf &apos;negative regulation of cellular component organization&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of barbed-end actin filament capping&apos; SubClassOf &apos;negative regulation of actin filament depolymerization&apos;</newAxiom>
<newAxiom>&apos;negative regulation of barbed-end actin filament capping&apos; SubClassOf &apos;negative regulation of actin filament polymerization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038176</classIRI>
<classLabel>positive regulation of SREBP signaling pathway in response to decreased oxygen levels</classLabel>
<newAxiom>&apos;positive regulation of SREBP signaling pathway in response to decreased oxygen levels&apos; SubClassOf &apos;positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901321</classIRI>
<classLabel>positive regulation of heart induction</classLabel>
<newAxiom>&apos;positive regulation of heart induction&apos; SubClassOf &apos;positive regulation of multicellular organismal process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901977</classIRI>
<classLabel>negative regulation of cell cycle checkpoint</classLabel>
<deletedAxiom>&apos;negative regulation of cell cycle checkpoint&apos; SubClassOf &apos;negative regulation of cellular process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of cell cycle checkpoint&apos; SubClassOf &apos;negative regulation of cell cycle&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070426</classIRI>
<classLabel>positive regulation of nucleotide-binding oligomerization domain containing signaling pathway</classLabel>
<deletedAxiom>&apos;positive regulation of nucleotide-binding oligomerization domain containing signaling pathway&apos; SubClassOf &apos;positive regulation of immune system process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of nucleotide-binding oligomerization domain containing signaling pathway&apos; SubClassOf &apos;positive regulation of innate immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060965</classIRI>
<classLabel>negative regulation of gene silencing by miRNA</classLabel>
<newAxiom>&apos;negative regulation of gene silencing by miRNA&apos; SubClassOf &apos;negative regulation of translation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060969</classIRI>
<classLabel>negative regulation of gene silencing</classLabel>
<newAxiom>&apos;negative regulation of gene silencing&apos; SubClassOf &apos;negative regulation of gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060520</classIRI>
<classLabel>activation of prostate induction by androgen receptor signaling pathway</classLabel>
<deletedAxiom>&apos;activation of prostate induction by androgen receptor signaling pathway&apos; SubClassOf &apos;positive regulation of developmental process&apos;</deletedAxiom>
<newAxiom>&apos;activation of prostate induction by androgen receptor signaling pathway&apos; SubClassOf &apos;positive regulation of embryonic development&apos;</newAxiom>
<newAxiom>&apos;activation of prostate induction by androgen receptor signaling pathway&apos; SubClassOf &apos;positive regulation of reproductive process&apos;</newAxiom>
<newAxiom>&apos;activation of prostate induction by androgen receptor signaling pathway&apos; SubClassOf &apos;positive regulation of morphogenesis of an epithelium&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035421</classIRI>
<classLabel>activation of MAPKK activity involved in innate immune response</classLabel>
<newAxiom>&apos;activation of MAPKK activity involved in innate immune response&apos; SubClassOf &apos;activation of MAPK activity involved in innate immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035422</classIRI>
<classLabel>activation of MAPKKK activity involved in innate immune response</classLabel>
<newAxiom>&apos;activation of MAPKKK activity involved in innate immune response&apos; SubClassOf &apos;activation of MAPKK activity involved in innate immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060369</classIRI>
<classLabel>positive regulation of Fc receptor mediated stimulatory signaling pathway</classLabel>
<deletedAxiom>&apos;positive regulation of Fc receptor mediated stimulatory signaling pathway&apos; SubClassOf &apos;positive regulation of immune system process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of Fc receptor mediated stimulatory signaling pathway&apos; SubClassOf &apos;positive regulation of immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905091</classIRI>
<classLabel>positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization</classLabel>
<deletedAxiom>&apos;positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization&apos; SubClassOf &apos;positive regulation of cellular process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization&apos; SubClassOf &apos;positive regulation of macromitophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905098</classIRI>
<classLabel>negative regulation of guanyl-nucleotide exchange factor activity</classLabel>
<deletedAxiom>&apos;negative regulation of guanyl-nucleotide exchange factor activity&apos; SubClassOf &apos;negative regulation of molecular function&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of guanyl-nucleotide exchange factor activity&apos; SubClassOf &apos;negative regulation of binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905099</classIRI>
<classLabel>positive regulation of guanyl-nucleotide exchange factor activity</classLabel>
<deletedAxiom>&apos;positive regulation of guanyl-nucleotide exchange factor activity&apos; SubClassOf &apos;positive regulation of molecular function&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of guanyl-nucleotide exchange factor activity&apos; SubClassOf &apos;positive regulation of GTPase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050857</classIRI>
<classLabel>positive regulation of antigen receptor-mediated signaling pathway</classLabel>
<deletedAxiom>&apos;positive regulation of antigen receptor-mediated signaling pathway&apos; SubClassOf &apos;positive regulation of immune system process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of antigen receptor-mediated signaling pathway&apos; SubClassOf &apos;positive regulation of immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905309</classIRI>
<classLabel>positive regulation of cohesin loading</classLabel>
<newAxiom>&apos;positive regulation of cohesin loading&apos; SubClassOf &apos;positive regulation of DNA binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905338</classIRI>
<classLabel>negative regulation of cohesin unloading</classLabel>
<deletedAxiom>&apos;negative regulation of cohesin unloading&apos; SubClassOf &apos;negative regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of cohesin unloading&apos; SubClassOf &apos;negative regulation of DNA binding&apos;</newAxiom>
<newAxiom>&apos;negative regulation of cohesin unloading&apos; SubClassOf &apos;negative regulation of sister chromatid cohesion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904501</classIRI>
<classLabel>positive regulation of chromatin-mediated maintenance of transcription</classLabel>
<newAxiom>&apos;positive regulation of chromatin-mediated maintenance of transcription&apos; SubClassOf &apos;positive regulation of transcription, DNA-templated&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030712</classIRI>
<classLabel>negative regulation of border follicle cell delamination</classLabel>
<newAxiom>&apos;negative regulation of border follicle cell delamination&apos; SubClassOf &apos;negative regulation of cell-cell adhesion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900245</classIRI>
<classLabel>positive regulation of MDA-5 signaling pathway</classLabel>
<deletedAxiom>&apos;positive regulation of MDA-5 signaling pathway&apos; SubClassOf &apos;positive regulation of defense response&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of MDA-5 signaling pathway&apos; SubClassOf &apos;positive regulation of cytokine production&apos;</newAxiom>
<newAxiom>&apos;positive regulation of MDA-5 signaling pathway&apos; SubClassOf &apos;positive regulation of innate immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900246</classIRI>
<classLabel>positive regulation of RIG-I signaling pathway</classLabel>
<deletedAxiom>&apos;positive regulation of RIG-I signaling pathway&apos; SubClassOf &apos;positive regulation of defense response&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of RIG-I signaling pathway&apos; SubClassOf &apos;positive regulation of innate immune response&apos;</newAxiom>
<newAxiom>&apos;positive regulation of RIG-I signaling pathway&apos; SubClassOf &apos;positive regulation of cytokine production&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900237</classIRI>
<classLabel>positive regulation of induction of conjugation with cellular fusion</classLabel>
<deletedAxiom>&apos;positive regulation of induction of conjugation with cellular fusion&apos; SubClassOf &apos;positive regulation of biological process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of induction of conjugation with cellular fusion&apos; SubClassOf &apos;regulation of conjugation with cellular fusion&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of induction of conjugation with cellular fusion&apos; SubClassOf &apos;positive regulation of conjugation with cellular fusion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900281</classIRI>
<classLabel>positive regulation of CD4-positive, alpha-beta T cell costimulation</classLabel>
<newAxiom>&apos;positive regulation of CD4-positive, alpha-beta T cell costimulation&apos; SubClassOf &apos;positive regulation of CD4-positive, alpha-beta T cell activation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900273</classIRI>
<classLabel>positive regulation of long-term synaptic potentiation</classLabel>
<deletedAxiom>&apos;positive regulation of long-term synaptic potentiation&apos; SubClassOf &apos;positive regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of long-term synaptic potentiation&apos; SubClassOf &apos;positive regulation of synaptic transmission&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900404</classIRI>
<classLabel>positive regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter</classLabel>
<deletedAxiom>&apos;positive regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;regulation of DNA repair&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;positive regulation of DNA repair&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900417</classIRI>
<classLabel>negative regulation of transmembrane transport by negative regulation of transcription from RNA polymerase II promoter</classLabel>
<newAxiom>&apos;negative regulation of transmembrane transport by negative regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;negative regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900453</classIRI>
<classLabel>negative regulation of long term synaptic depression</classLabel>
<deletedAxiom>&apos;negative regulation of long term synaptic depression&apos; SubClassOf &apos;negative regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of long term synaptic depression&apos; SubClassOf &apos;negative regulation of synaptic transmission&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900422</classIRI>
<classLabel>positive regulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter</classLabel>
<deletedAxiom>&apos;positive regulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;regulation of cellular alcohol catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;positive regulation of cellular alcohol catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900423</classIRI>
<classLabel>positive regulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter</classLabel>
<deletedAxiom>&apos;positive regulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;regulation of mating type switching&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;positive regulation of mating type switching by regulation of transcription from RNA polymerase II promoter&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900465</classIRI>
<classLabel>negative regulation of arginine catabolic process by negative regulation of transcription from RNA polymerase II promoter</classLabel>
<deletedAxiom>&apos;negative regulation of arginine catabolic process by negative regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;regulation of arginine catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of arginine catabolic process by negative regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;negative regulation of arginine catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900526</classIRI>
<classLabel>negative regulation of phosphatidylserine biosynthetic process by negative regulation of transcription from RNA polymerase II promoter</classLabel>
<newAxiom>&apos;negative regulation of phosphatidylserine biosynthetic process by negative regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;negative regulation of phosphatidylserine biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007256</classIRI>
<classLabel>activation of JNKK activity</classLabel>
<deletedAxiom>&apos;activation of JNKK activity&apos; SubClassOf &apos;positive regulation of JNK cascade&apos;</deletedAxiom>
<deletedAxiom>&apos;activation of JNKK activity&apos; SubClassOf &apos;regulation of JUN kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;activation of JNKK activity&apos; SubClassOf &apos;positive regulation of JUN kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071510</classIRI>
<classLabel>activation of MAPKKK activity involved in conjugation with cellular fusion</classLabel>
<deletedAxiom>&apos;activation of MAPKKK activity involved in conjugation with cellular fusion&apos; SubClassOf &apos;positive regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion&apos;</deletedAxiom>
<newAxiom>&apos;activation of MAPKKK activity involved in conjugation with cellular fusion&apos; SubClassOf &apos;activation of MAPKK activity involved in conjugation with cellular fusion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071509</classIRI>
<classLabel>activation of MAPKK activity involved in conjugation with cellular fusion</classLabel>
<deletedAxiom>&apos;activation of MAPKK activity involved in conjugation with cellular fusion&apos; SubClassOf &apos;positive regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion&apos;</deletedAxiom>
<newAxiom>&apos;activation of MAPKK activity involved in conjugation with cellular fusion&apos; SubClassOf &apos;activation of MAPK activity involved in conjugation with cellular fusion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051918</classIRI>
<classLabel>negative regulation of fibrinolysis</classLabel>
<deletedAxiom>&apos;negative regulation of fibrinolysis&apos; SubClassOf &apos;negative regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of fibrinolysis&apos; SubClassOf &apos;negative regulation of blood coagulation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904001</classIRI>
<classLabel>positive regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter</classLabel>
<deletedAxiom>&apos;positive regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;regulation of pyrimidine-containing compound salvage&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;positive regulation of pyrimidine-containing compound salvage&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904021</classIRI>
<classLabel>negative regulation of G-protein coupled receptor internalization</classLabel>
<newAxiom>&apos;negative regulation of G-protein coupled receptor internalization&apos; SubClassOf &apos;negative regulation of G-protein coupled receptor protein signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904324</classIRI>
<classLabel>negative regulation of inhibitory G-protein coupled receptor phosphorylation</classLabel>
<newAxiom>&apos;negative regulation of inhibitory G-protein coupled receptor phosphorylation&apos; SubClassOf &apos;negative regulation of G-protein coupled receptor protein signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903247</classIRI>
<classLabel>positive regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate</classLabel>
<deletedAxiom>&apos;positive regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate&apos; SubClassOf &apos;positive regulation of blood circulation&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate&apos; SubClassOf &apos;positive regulation of heart contraction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051280</classIRI>
<classLabel>negative regulation of release of sequestered calcium ion into cytosol</classLabel>
<newAxiom>&apos;negative regulation of release of sequestered calcium ion into cytosol&apos; SubClassOf &apos;negative regulation of sequestering of calcium ion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051127</classIRI>
<classLabel>positive regulation of actin nucleation</classLabel>
<deletedAxiom>&apos;positive regulation of actin nucleation&apos; SubClassOf &apos;positive regulation of supramolecular fiber organization&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of actin nucleation&apos; SubClassOf &apos;positive regulation of actin filament polymerization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903704</classIRI>
<classLabel>negative regulation of production of siRNA involved in RNA interference</classLabel>
<deletedAxiom>&apos;negative regulation of production of siRNA involved in RNA interference&apos; SubClassOf &apos;negative regulation of gene expression&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903799</classIRI>
<classLabel>negative regulation of production of miRNAs involved in gene silencing by miRNA</classLabel>
<deletedAxiom>&apos;negative regulation of production of miRNAs involved in gene silencing by miRNA&apos; SubClassOf &apos;negative regulation of gene expression&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031936</classIRI>
<classLabel>negative regulation of chromatin silencing</classLabel>
<newAxiom>&apos;negative regulation of chromatin silencing&apos; SubClassOf &apos;negative regulation of transcription, DNA-templated&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006981</classIRI>
<classLabel>activation of SoxR protein</classLabel>
<deletedAxiom>&apos;activation of SoxR protein&apos; SubClassOf &apos;cellular response to redox state&apos;</deletedAxiom>
<deletedAxiom>&apos;activation of SoxR protein&apos; SubClassOf &apos;cellular response to chemical stimulus&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045906</classIRI>
<classLabel>negative regulation of vasoconstriction</classLabel>
<newAxiom>&apos;negative regulation of vasoconstriction&apos; SubClassOf &apos;negative regulation of blood vessel diameter&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045756</classIRI>
<classLabel>positive regulation of initiation of acetate catabolic process by acetate</classLabel>
<newAxiom>&apos;positive regulation of initiation of acetate catabolic process by acetate&apos; SubClassOf &apos;positive regulation of acetate catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008588</classIRI>
<classLabel>release of cytoplasmic sequestered NF-kappaB</classLabel>
<deletedAxiom>&apos;release of cytoplasmic sequestered NF-kappaB&apos; SubClassOf &apos;negative regulation of cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;release of cytoplasmic sequestered NF-kappaB&apos; SubClassOf &apos;negative regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;release of cytoplasmic sequestered NF-kappaB&apos; SubClassOf &apos;negative regulation of NF-kappaB import into nucleus&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902426</classIRI>
<classLabel>deactivation of mitotic spindle assembly checkpoint</classLabel>
<deletedAxiom>&apos;deactivation of mitotic spindle assembly checkpoint&apos; SubClassOf &apos;negative regulation of cell cycle process&apos;</deletedAxiom>
<deletedAxiom>&apos;deactivation of mitotic spindle assembly checkpoint&apos; SubClassOf &apos;negative regulation of mitotic cell cycle&apos;</deletedAxiom>
<newAxiom>&apos;deactivation of mitotic spindle assembly checkpoint&apos; SubClassOf &apos;negative regulation of mitotic metaphase/anaphase transition&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042801</classIRI>
<classLabel>polo kinase kinase activity</classLabel>
<deletedAxiom>&apos;polo kinase kinase activity&apos; SubClassOf &apos;signal transducer, downstream of receptor, with serine/threonine kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902373</classIRI>
<classLabel>negative regulation of mRNA catabolic process</classLabel>
<newAxiom>&apos;negative regulation of mRNA catabolic process&apos; SubClassOf &apos;negative regulation of gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902505</classIRI>
<classLabel>negative regulation of signal transduction involved in mitotic G2 DNA damage checkpoint</classLabel>
<newAxiom>&apos;negative regulation of signal transduction involved in mitotic G2 DNA damage checkpoint&apos; SubClassOf &apos;negative regulation of G2/M transition of mitotic cell cycle&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042655</classIRI>
<classLabel>activation of JNKKK activity</classLabel>
<deletedAxiom>&apos;activation of JNKKK activity&apos; SubClassOf &apos;regulation of JUN kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;activation of JNKKK activity&apos; SubClassOf &apos;positive regulation of JNK cascade&apos;</deletedAxiom>
<newAxiom>&apos;activation of JNKKK activity&apos; SubClassOf &apos;positive regulation of JUN kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902879</classIRI>
<classLabel>negative regulation of BMP signaling pathway involved in spinal cord association neuron specification</classLabel>
<newAxiom>&apos;negative regulation of BMP signaling pathway involved in spinal cord association neuron specification&apos; SubClassOf &apos;negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902887</classIRI>
<classLabel>positive regulation of proteasome-activating ATPase activity</classLabel>
<deletedAxiom>&apos;positive regulation of proteasome-activating ATPase activity&apos; SubClassOf &apos;positive regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of proteasome-activating ATPase activity&apos; SubClassOf &apos;positive regulation of proteasomal protein catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032848</classIRI>
<classLabel>negative regulation of cellular pH reduction</classLabel>
<newAxiom>&apos;negative regulation of cellular pH reduction&apos; SubClassOf &apos;intracellular pH reduction&apos;</newAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102513</classIRI>
<classLabel>delphinidin 3-O-glucoside 5-O-glucosyltransferase (vanilloyl-glucose dependent) activity</classLabel>
<newAxiom>'delphinidin 3-O-glucoside 5-O-glucosyltransferase (vanilloyl-glucose dependent) activity' SubClassOf 'transferase activity, transferring hexosyl groups'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102515</classIRI>
<classLabel>pelargonidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity</classLabel>
<newAxiom>'pelargonidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity' SubClassOf 'transferase activity, transferring hexosyl groups'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102516</classIRI>
<classLabel>delphinidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity</classLabel>
<newAxiom>'delphinidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity' SubClassOf 'transferase activity, transferring hexosyl groups'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102343</classIRI>
<classLabel>3-hydroxy-arachidoyl-CoA dehydratase activity</classLabel>
<newAxiom>'3-hydroxy-arachidoyl-CoA dehydratase activity' SubClassOf 'hydro-lyase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102311</classIRI>
<classLabel>8-hydroxygeraniol dehydrogenase activity</classLabel>
<newAxiom>'8-hydroxygeraniol dehydrogenase activity' SubClassOf 'oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102303</classIRI>
<classLabel>resveratrol 3,5-O-dimethyltransferase activity</classLabel>
<newAxiom>'resveratrol 3,5-O-dimethyltransferase activity' SubClassOf 'methyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102305</classIRI>
<classLabel>(13E)-labda-7,13-dien-15-ol synthase activity</classLabel>
<newAxiom>'(13E)-labda-7,13-dien-15-ol synthase activity' SubClassOf 'diphosphoric monoester hydrolase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102317</classIRI>
<classLabel>4-methylaminobutyrate oxidase (demethylating) activity</classLabel>
<newAxiom>'4-methylaminobutyrate oxidase (demethylating) activity' SubClassOf 'oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102195</classIRI>
<classLabel>UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--D-lysine ligase activity</classLabel>
<newAxiom>'UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--D-lysine ligase activity' SubClassOf 'acid-amino acid ligase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102196</classIRI>
<classLabel>cortisol dehydrogenase activity</classLabel>
<newAxiom>'cortisol dehydrogenase activity' SubClassOf 'oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102152</classIRI>
<classLabel>Delta12-linoleate epoxygenase activity</classLabel>
<newAxiom>'Delta12-linoleate epoxygenase activity' SubClassOf 'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102142</classIRI>
<classLabel>[dermatan sulfate]-L-iduronyl 2-Osulfotransferase activity</classLabel>
<newAxiom>'[dermatan sulfate]-L-iduronyl 2-Osulfotransferase activity' SubClassOf 'sulfotransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102149</classIRI>
<classLabel>farnesylcysteine lyase activity</classLabel>
<newAxiom>'farnesylcysteine lyase activity' SubClassOf 'oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102175</classIRI>
<classLabel>3-beta-hydroxysteroid dehydrogenase/C4-decarboxylase activity</classLabel>
<newAxiom>'3-beta-hydroxysteroid dehydrogenase/C4-decarboxylase activity' SubClassOf 'oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102179</classIRI>
<classLabel>24-ethylidenelophenol 4alpha-methyl oxidase activity</classLabel>
<newAxiom>'24-ethylidenelophenol 4alpha-methyl oxidase activity' SubClassOf 'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102166</classIRI>
<classLabel>[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity</classLabel>
<newAxiom>'[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity' SubClassOf 'hydrolase activity, hydrolyzing O-glycosyl compounds'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102167</classIRI>
<classLabel>[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity</classLabel>
<newAxiom>'[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity' SubClassOf 'hydrolase activity, hydrolyzing O-glycosyl compounds'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102131</classIRI>
<classLabel>3-oxo-glutaryl-[acp] methyl ester reductase activity</classLabel>
<newAxiom>'3-oxo-glutaryl-[acp] methyl ester reductase activity' SubClassOf 'oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102127</classIRI>
<classLabel>8-oxoguanine deaminase activity</classLabel>
<newAxiom>'8-oxoguanine deaminase activity' SubClassOf 'hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102067</classIRI>
<classLabel>geranylgeranyl diphosphate reductase activity</classLabel>
<newAxiom>'geranylgeranyl diphosphate reductase activity' SubClassOf 'oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102087</classIRI>
<classLabel>N-benzoyl-L-glutamate synthetase activity</classLabel>
<newAxiom>'N-benzoyl-L-glutamate synthetase activity' SubClassOf 'ligase activity, forming carbon-nitrogen bonds'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102026</classIRI>
<classLabel>ferric dicitrate transporter activity</classLabel>
<newAxiom>'ferric dicitrate transporter activity' SubClassOf 'hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>