<?xml version="1.0"?>
<diffReport>
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77
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18
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0
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<changedClass>
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</changedClass>
<changedClass>
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<classLabel>mRNA stabilization</classLabel>
<newAxiom>&apos;mRNA stabilization&apos; SubClassOf &apos;negative regulation of mRNA catabolic process&apos;</newAxiom>
<newAxiom>&apos;mRNA stabilization&apos; SubClassOf &apos;negatively regulates&apos; some &apos;mRNA catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000759</classIRI>
<classLabel>regulation of N-terminal peptidyl-lysine acetylation</classLabel>
<newAxiom>&apos;regulation of N-terminal peptidyl-lysine acetylation&apos; SubClassOf &apos;regulation of protein maturation&apos;</newAxiom>
</changedClass>
<changedClass>
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<classLabel>positive regulation of N-terminal peptidyl-lysine acetylation</classLabel>
<newAxiom>&apos;positive regulation of N-terminal peptidyl-lysine acetylation&apos; SubClassOf &apos;positive regulation of protein maturation&apos;</newAxiom>
</changedClass>
<changedClass>
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<classLabel>negative regulation of N-terminal peptidyl-lysine acetylation</classLabel>
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</changedClass>
<changedClass>
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<classLabel>negative regulation of 3&apos;-UTR-mediated mRNA stabilization</classLabel>
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</changedClass>
<changedClass>
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<newAxiom>&apos;positive regulation of 3&apos;-UTR-mediated mRNA stabilization&apos; SubClassOf &apos;positive regulation of gene expression&apos;</newAxiom>
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</changedClass>
<changedClass>
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<classLabel>nicotine metabolic process</classLabel>
<deletedAxiom>&apos;nicotine metabolic process&apos; SubClassOf &apos;alkaloid metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;nicotine metabolic process&apos; SubClassOf &apos;pyridine-containing compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
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<classLabel>RNA stabilization</classLabel>
<newAxiom>&apos;RNA stabilization&apos; SubClassOf &apos;negative regulation of RNA catabolic process&apos;</newAxiom>
<newAxiom>&apos;RNA stabilization&apos; SubClassOf &apos;negatively regulates&apos; some &apos;RNA catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
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<classLabel>regulation of RNA stability</classLabel>
<newAxiom>&apos;regulation of RNA stability&apos; SubClassOf &apos;regulation of RNA metabolic process&apos;</newAxiom>
<newAxiom>&apos;regulation of RNA stability&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</newAxiom>
<newAxiom>&apos;regulation of RNA stability&apos; SubClassOf &apos;regulates&apos; some &apos;RNA catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
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<classLabel>regulation of mRNA stability</classLabel>
<newAxiom>&apos;regulation of mRNA stability&apos; SubClassOf &apos;regulates&apos; some &apos;mRNA catabolic process&apos;</newAxiom>
<newAxiom>&apos;regulation of mRNA stability&apos; SubClassOf &apos;regulation of mRNA catabolic process&apos;</newAxiom>
</changedClass>
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<newAxiom>http://purl.obolibrary.org/obo/CHEBI_50906 SubClassOf http://purl.obolibrary.org/obo/BFO_0000017</newAxiom>
</changedClass>
<changedClass>
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<classLabel>flurbiprofen binding</classLabel>
<newAxiom>&apos;flurbiprofen binding&apos; SubClassOf &apos;monocarboxylic acid binding&apos;</newAxiom>
</changedClass>
<changedClass>
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</changedClass>
<changedClass>
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<classLabel>RNA destabilization</classLabel>
<newAxiom>&apos;RNA destabilization&apos; SubClassOf &apos;positively regulates&apos; some &apos;RNA catabolic process&apos;</newAxiom>
<newAxiom>&apos;RNA destabilization&apos; SubClassOf &apos;positive regulation of RNA metabolic process&apos;</newAxiom>
<newAxiom>&apos;RNA destabilization&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
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<classLabel>response to nicotine</classLabel>
<deletedAxiom>&apos;response to nicotine&apos; SubClassOf &apos;response to alkaloid&apos;</deletedAxiom>
<deletedAxiom>&apos;response to nicotine&apos; SubClassOf &apos;response to organic cyclic compound&apos;</deletedAxiom>
<newAxiom>&apos;response to nicotine&apos; SubClassOf &apos;response to chemical&apos;</newAxiom>
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</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015898</classIRI>
<classLabel>amiloride transport</classLabel>
<deletedAxiom>&apos;amiloride transport&apos; SubClassOf &apos;amide transport&apos;</deletedAxiom>
<newAxiom>&apos;amiloride transport&apos; SubClassOf &apos;nitrogen compound transport&apos;</newAxiom>
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</changedClass>
<changedClass>
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<classLabel>negative regulation of N-terminal peptidyl-methionine acetylation</classLabel>
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</changedClass>
<changedClass>
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<classLabel>positive regulation of N-terminal peptidyl-methionine acetylation</classLabel>
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</changedClass>
<changedClass>
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<classLabel>regulation of N-terminal peptidyl-methionine acetylation</classLabel>
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</changedClass>
<changedClass>
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<classLabel>amiloride:proton antiporter activity</classLabel>
<deletedAxiom>&apos;amiloride:proton antiporter activity&apos; SubClassOf &apos;amide transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
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</changedClass>
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</changedClass>
<changedClass>
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<classLabel>5-methylcytosine metabolic process</classLabel>
<newAxiom>&apos;5-methylcytosine metabolic process&apos; SubClassOf &apos;cellular aromatic compound metabolic process&apos;</newAxiom>
</changedClass>
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</changedClass>
<changedClass>
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<classLabel>nicotine catabolic process</classLabel>
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<deletedAxiom>&apos;nicotine catabolic process&apos; SubClassOf &apos;alkaloid catabolic process&apos;</deletedAxiom>
</changedClass>
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</changedClass>
<changedClass>
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<classLabel>regulation of rRNA stability</classLabel>
<newAxiom>&apos;regulation of rRNA stability&apos; SubClassOf &apos;regulates&apos; some &apos;rRNA catabolic process&apos;</newAxiom>
<newAxiom>&apos;regulation of rRNA stability&apos; SubClassOf &apos;regulation of rRNA catabolic process&apos;</newAxiom>
</changedClass>
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</changedClass>
<changedClass>
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<classLabel>cellular response to nicotine</classLabel>
<deletedAxiom>&apos;cellular response to nicotine&apos; SubClassOf &apos;cellular response to organic cyclic compound&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular response to nicotine&apos; SubClassOf &apos;cellular response to alkaloid&apos;</deletedAxiom>
</changedClass>
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</changedClass>
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</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046146</classIRI>
<classLabel>tetrahydrobiopterin metabolic process</classLabel>
<newAxiom>&apos;tetrahydrobiopterin metabolic process&apos; SubClassOf &apos;diol metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046147</classIRI>
<classLabel>tetrahydrobiopterin catabolic process</classLabel>
<newAxiom>&apos;tetrahydrobiopterin catabolic process&apos; SubClassOf &apos;diol catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046082</classIRI>
<classLabel>5-methylcytosine biosynthetic process</classLabel>
<newAxiom>&apos;5-methylcytosine biosynthetic process&apos; SubClassOf &apos;aromatic compound biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
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<classLabel>tRNA destabilization</classLabel>
<newAxiom>&apos;tRNA destabilization&apos; SubClassOf &apos;positive regulation of tRNA catabolic process&apos;</newAxiom>
<newAxiom>&apos;tRNA destabilization&apos; SubClassOf &apos;positively regulates&apos; some &apos;tRNA catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
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<classLabel>tRNA stabilization</classLabel>
<newAxiom>&apos;tRNA stabilization&apos; SubClassOf &apos;negatively regulates&apos; some &apos;tRNA catabolic process&apos;</newAxiom>
<newAxiom>&apos;tRNA stabilization&apos; SubClassOf &apos;negative regulation of tRNA catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
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<classLabel>regulation of tRNA stability</classLabel>
<newAxiom>&apos;regulation of tRNA stability&apos; SubClassOf &apos;regulation of tRNA catabolic process&apos;</newAxiom>
<newAxiom>&apos;regulation of tRNA stability&apos; SubClassOf &apos;regulates&apos; some &apos;tRNA catabolic process&apos;</newAxiom>
</changedClass>
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</changedClass>
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</changedClass>
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</changedClass>
<changedClass>
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<classLabel>cellular response to amiloride</classLabel>
<deletedAxiom>&apos;cellular response to amiloride&apos; SubClassOf &apos;cellular response to oxygen-containing compound&apos;</deletedAxiom>
</changedClass>
<changedClass>
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<classLabel>response to amiloride</classLabel>
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</changedClass>
<changedClass>
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<classLabel>mRNA destabilization</classLabel>
<newAxiom>&apos;mRNA destabilization&apos; SubClassOf &apos;positive regulation of mRNA catabolic process&apos;</newAxiom>
<newAxiom>&apos;mRNA destabilization&apos; SubClassOf &apos;positively regulates&apos; some &apos;mRNA catabolic process&apos;</newAxiom>
</changedClass>
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</changedClass>
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</changedClass>
<changedClass>
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<classLabel>tetrahydrobiopterin biosynthetic process</classLabel>
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</changedClass>
<changedClass>
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<classLabel>N-terminal protein amino acid acetylation</classLabel>
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</changedClass>
<changedClass>
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</changedClass>
<changedClass>
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</changedClass>
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<changedClass>
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