<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
54
</numberChangedClasses>
<numberNewClasses>
0
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019182</classIRI>
<classLabel>histamine-gated chloride channel activity</classLabel>
<deletedAxiom>&apos;histamine-gated chloride channel activity&apos; SubClassOf &apos;ligand-gated anion channel activity&apos;</deletedAxiom>
<newAxiom>&apos;histamine-gated chloride channel activity&apos; EquivalentTo &apos;channel activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_17996) and (&apos;regulated by&apos; some &apos;histamine binding&apos;)</newAxiom>
<newAxiom>&apos;histamine-gated chloride channel activity&apos; SubClassOf &apos;regulated by&apos; some &apos;histamine binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019183</classIRI>
<classLabel>histamine-gated chloride channel complex</classLabel>
<deletedAxiom>&apos;histamine-gated chloride channel complex&apos; SubClassOf &apos;plasma membrane receptor complex&apos;</deletedAxiom>
<newAxiom>&apos;histamine-gated chloride channel complex&apos; SubClassOf &apos;plasma membrane part&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097603</classIRI>
<classLabel>temperature-gated ion channel activity</classLabel>
<deletedAxiom>&apos;temperature-gated ion channel activity&apos; SubClassOf &apos;gated channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;temperature-gated ion channel activity&apos; SubClassOf &apos;ion channel activity&apos;</deletedAxiom>
<newAxiom>&apos;temperature-gated ion channel activity&apos; SubClassOf &apos;ion gated channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000277</classIRI>
<classLabel>positive regulation of oxidative phosphorylation uncoupler activity</classLabel>
<deletedAxiom>&apos;positive regulation of oxidative phosphorylation uncoupler activity&apos; SubClassOf &apos;positive regulation of transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000276</classIRI>
<classLabel>negative regulation of oxidative phosphorylation uncoupler activity</classLabel>
<deletedAxiom>&apos;negative regulation of oxidative phosphorylation uncoupler activity&apos; SubClassOf &apos;negative regulation of transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004972</classIRI>
<classLabel>NMDA glutamate receptor activity</classLabel>
<deletedAxiom>&apos;NMDA glutamate receptor activity&apos; SubClassOf &apos;voltage-gated ion channel activity&apos;</deletedAxiom>
<newAxiom>&apos;NMDA glutamate receptor activity&apos; SubClassOf &apos;voltage-gated cation channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901218</classIRI>
<classLabel>negative regulation of holin activity</classLabel>
<deletedAxiom>&apos;negative regulation of holin activity&apos; SubClassOf &apos;negative regulation of transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043855</classIRI>
<classLabel>cyclic nucleotide-gated ion channel activity</classLabel>
<newAxiom>&apos;cyclic nucleotide-gated ion channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_24870) and (&apos;regulated by&apos; some &apos;cyclic nucleotide binding&apos;)</newAxiom>
<newAxiom>&apos;cyclic nucleotide-gated ion channel activity&apos; SubClassOf &apos;regulated by&apos; some &apos;cyclic nucleotide binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901585</classIRI>
<classLabel>regulation of acid-sensing ion channel activity</classLabel>
<deletedAxiom>&apos;regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;regulation of receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901586</classIRI>
<classLabel>negative regulation of acid-sensing ion channel activity</classLabel>
<deletedAxiom>&apos;negative regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;negative regulation of receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901587</classIRI>
<classLabel>positive regulation of acid-sensing ion channel activity</classLabel>
<deletedAxiom>&apos;positive regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;positive regulation of receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901487</classIRI>
<classLabel>negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolic process in response to increased oxygen levels</classLabel>
<deletedAxiom>&apos;negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolic process in response to increased oxygen levels&apos; SubClassOf &apos;negative regulation of SREBP signaling pathway in response to increased oxygen levels&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolic process in response to increased oxygen levels&apos; SubClassOf &apos;negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolic process in response to increased oxygen levels&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901979</classIRI>
<classLabel>regulation of inward rectifier potassium channel activity</classLabel>
<deletedAxiom>&apos;regulation of inward rectifier potassium channel activity&apos; SubClassOf &apos;regulation of receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901980</classIRI>
<classLabel>positive regulation of inward rectifier potassium channel activity</classLabel>
<deletedAxiom>&apos;positive regulation of inward rectifier potassium channel activity&apos; SubClassOf &apos;positive regulation of receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060314</classIRI>
<classLabel>regulation of ryanodine-sensitive calcium-release channel activity</classLabel>
<deletedAxiom>&apos;regulation of ryanodine-sensitive calcium-release channel activity&apos; SubClassOf &apos;regulation of receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060315</classIRI>
<classLabel>negative regulation of ryanodine-sensitive calcium-release channel activity</classLabel>
<deletedAxiom>&apos;negative regulation of ryanodine-sensitive calcium-release channel activity&apos; SubClassOf &apos;negative regulation of receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060316</classIRI>
<classLabel>positive regulation of ryanodine-sensitive calcium-release channel activity</classLabel>
<deletedAxiom>&apos;positive regulation of ryanodine-sensitive calcium-release channel activity&apos; SubClassOf &apos;positive regulation of receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035381</classIRI>
<classLabel>ATP-gated ion channel activity</classLabel>
<deletedAxiom>&apos;ATP-gated ion channel activity&apos; SubClassOf &apos;ligand-gated ion channel activity&apos;</deletedAxiom>
<newAxiom>&apos;ATP-gated ion channel activity&apos; SubClassOf &apos;regulated by&apos; some &apos;ATP binding&apos;</newAxiom>
<newAxiom>&apos;ATP-gated ion channel activity&apos; SubClassOf &apos;ligand-gated channel activity&apos;</newAxiom>
<newAxiom>&apos;ATP-gated ion channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_24870) and (&apos;regulated by&apos; some &apos;ATP binding&apos;)</newAxiom>
<newAxiom>&apos;ATP-gated ion channel activity&apos; SubClassOf &apos;ion gated channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904602</classIRI>
<classLabel>serotonin-activated cation-selective channel complex</classLabel>
<deletedAxiom>&apos;serotonin-activated cation-selective channel complex&apos; SubClassOf &apos;serotonin receptor complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015276</classIRI>
<classLabel>ligand-gated ion channel activity</classLabel>
<deletedAxiom>&apos;ligand-gated ion channel activity&apos; SubClassOf &apos;ion channel activity&apos;</deletedAxiom>
<newAxiom>&apos;ligand-gated ion channel activity&apos; SubClassOf &apos;ion gated channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015081</classIRI>
<classLabel>sodium ion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;sodium ion transmembrane transporter activity&apos; SubClassOf &apos;part of&apos; some &apos;sodium ion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;sodium ion transmembrane transporter activity&apos; SubClassOf &apos;part of&apos; some &apos;sodium ion transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005225</classIRI>
<classLabel>volume-sensitive anion channel activity</classLabel>
<deletedAxiom>&apos;volume-sensitive anion channel activity&apos; SubClassOf &apos;part of&apos; some &apos;regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005231</classIRI>
<classLabel>excitatory extracellular ligand-gated ion channel activity</classLabel>
<deletedAxiom>&apos;excitatory extracellular ligand-gated ion channel activity&apos; SubClassOf &apos;transmembrane signaling receptor activity&apos;</deletedAxiom>
<newAxiom>&apos;excitatory extracellular ligand-gated ion channel activity&apos; SubClassOf &apos;signal transducer activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005244</classIRI>
<classLabel>voltage-gated ion channel activity</classLabel>
<deletedAxiom>&apos;voltage-gated ion channel activity&apos; SubClassOf &apos;part of&apos; some &apos;regulation of ion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;voltage-gated ion channel activity&apos; SubClassOf &apos;ion channel activity&apos;</deletedAxiom>
<newAxiom>&apos;voltage-gated ion channel activity&apos; EquivalentTo &apos;voltage-gated channel activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_24870)</newAxiom>
<newAxiom>&apos;voltage-gated ion channel activity&apos; SubClassOf &apos;ion gated channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005245</classIRI>
<classLabel>voltage-gated calcium channel activity</classLabel>
<newAxiom>&apos;voltage-gated calcium channel activity&apos; EquivalentTo &apos;voltage-gated channel activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_39123)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005247</classIRI>
<classLabel>voltage-gated chloride channel activity</classLabel>
<newAxiom>&apos;voltage-gated chloride channel activity&apos; EquivalentTo &apos;voltage-gated channel activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_17996)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022841</classIRI>
<classLabel>potassium ion leak channel activity</classLabel>
<newAxiom>&apos;potassium ion leak channel activity&apos; EquivalentTo &apos;leak channel activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_29103)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022839</classIRI>
<classLabel>ion gated channel activity</classLabel>
<newAxiom>&apos;ion gated channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_24870)</newAxiom>
<newAxiom>&apos;ion gated channel activity&apos; SubClassOf &apos;ion channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022834</classIRI>
<classLabel>ligand-gated channel activity</classLabel>
<deletedAxiom>&apos;ligand-gated channel activity&apos; SubClassOf &apos;transmembrane receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022832</classIRI>
<classLabel>voltage-gated channel activity</classLabel>
<deletedAxiom>&apos;voltage-gated channel activity&apos; SubClassOf &apos;part of&apos; some &apos;regulation of transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022835</classIRI>
<classLabel>transmitter-gated channel activity</classLabel>
<deletedAxiom>&apos;transmitter-gated channel activity&apos; SubClassOf &apos;transmembrane signaling receptor activity&apos;</deletedAxiom>
<newAxiom>&apos;transmitter-gated channel activity&apos; SubClassOf &apos;regulated by&apos; some &apos;neurotransmitter binding&apos;</newAxiom>
<newAxiom>&apos;transmitter-gated channel activity&apos; EquivalentTo &apos;channel activity&apos; and (&apos;regulated by&apos; some &apos;neurotransmitter binding&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022850</classIRI>
<classLabel>serotonin-gated cation-selective channel activity</classLabel>
<deletedAxiom>&apos;serotonin-gated cation-selective channel activity&apos; SubClassOf &apos;serotonin receptor activity&apos;</deletedAxiom>
<newAxiom>&apos;serotonin-gated cation-selective channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_36916) and (&apos;regulated by&apos; some &apos;serotonin binding&apos;)</newAxiom>
<newAxiom>&apos;serotonin-gated cation-selective channel activity&apos; SubClassOf &apos;regulated by&apos; some &apos;serotonin binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022843</classIRI>
<classLabel>voltage-gated cation channel activity</classLabel>
<newAxiom>&apos;voltage-gated cation channel activity&apos; EquivalentTo &apos;voltage-gated channel activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_36916)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022848</classIRI>
<classLabel>acetylcholine-gated cation-selective channel activity</classLabel>
<deletedAxiom>&apos;acetylcholine-gated cation-selective channel activity&apos; SubClassOf &apos;ligand-gated cation channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;acetylcholine-gated cation-selective channel activity&apos; SubClassOf &apos;acetylcholine receptor activity&apos;</deletedAxiom>
<newAxiom>&apos;acetylcholine-gated cation-selective channel activity&apos; SubClassOf &apos;cation channel activity&apos;</newAxiom>
<newAxiom>&apos;acetylcholine-gated cation-selective channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_36916) and (&apos;regulated by&apos; some &apos;acetylcholine binding&apos;)</newAxiom>
<newAxiom>&apos;acetylcholine-gated cation-selective channel activity&apos; SubClassOf &apos;regulated by&apos; some &apos;acetylcholine binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022857</classIRI>
<classLabel>transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;transmembrane transporter activity&apos; SubClassOf &apos;part of&apos; some &apos;transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022898</classIRI>
<classLabel>regulation of transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;regulation of transmembrane transporter activity&apos; SubClassOf &apos;regulation of transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061797</classIRI>
<classLabel>pH-gated chloride channel activity</classLabel>
<deletedAxiom>&apos;pH-gated chloride channel activity&apos; SubClassOf &apos;gated channel activity&apos;</deletedAxiom>
<newAxiom>&apos;pH-gated chloride channel activity&apos; SubClassOf &apos;ion gated channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099604</classIRI>
<classLabel>ligand-gated calcium channel activity</classLabel>
<deletedAxiom>&apos;ligand-gated calcium channel activity&apos; SubClassOf &apos;transmembrane signaling receptor activity&apos;</deletedAxiom>
<newAxiom>&apos;ligand-gated calcium channel activity&apos; SubClassOf &apos;signal transducer activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099099</classIRI>
<classLabel>G-protein gated ion channel activity</classLabel>
<deletedAxiom>&apos;G-protein gated ion channel activity&apos; SubClassOf &apos;gated channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;G-protein gated ion channel activity&apos; SubClassOf &apos;ion channel activity&apos;</deletedAxiom>
<newAxiom>&apos;G-protein gated ion channel activity&apos; SubClassOf &apos;ion gated channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903609</classIRI>
<classLabel>negative regulation of inward rectifier potassium channel activity</classLabel>
<deletedAxiom>&apos;negative regulation of inward rectifier potassium channel activity&apos; SubClassOf &apos;negative regulation of receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031587</classIRI>
<classLabel>positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity</classLabel>
<deletedAxiom>&apos;positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity&apos; SubClassOf &apos;positive regulation of receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031586</classIRI>
<classLabel>negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity</classLabel>
<deletedAxiom>&apos;negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity&apos; SubClassOf &apos;negative regulation of receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031585</classIRI>
<classLabel>regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity</classLabel>
<deletedAxiom>&apos;regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity&apos; SubClassOf &apos;regulation of receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008381</classIRI>
<classLabel>mechanically-gated ion channel activity</classLabel>
<deletedAxiom>&apos;mechanically-gated ion channel activity&apos; SubClassOf &apos;ion channel activity&apos;</deletedAxiom>
<newAxiom>&apos;mechanically-gated ion channel activity&apos; SubClassOf &apos;ion gated channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008308</classIRI>
<classLabel>voltage-gated anion channel activity</classLabel>
<deletedAxiom>&apos;voltage-gated anion channel activity&apos; SubClassOf &apos;part of&apos; some &apos;regulation of anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;voltage-gated anion channel activity&apos; EquivalentTo &apos;voltage-gated channel activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_22563)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990760</classIRI>
<classLabel>osmolarity-sensing cation channel activity</classLabel>
<deletedAxiom>&apos;osmolarity-sensing cation channel activity&apos; SubClassOf &apos;gated channel activity&apos;</deletedAxiom>
<newAxiom>&apos;osmolarity-sensing cation channel activity&apos; SubClassOf &apos;ion gated channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902159</classIRI>
<classLabel>regulation of cyclic nucleotide-gated ion channel activity</classLabel>
<deletedAxiom>&apos;regulation of cyclic nucleotide-gated ion channel activity&apos; SubClassOf &apos;regulation of receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902160</classIRI>
<classLabel>negative regulation of cyclic nucleotide-gated ion channel activity</classLabel>
<deletedAxiom>&apos;negative regulation of cyclic nucleotide-gated ion channel activity&apos; SubClassOf &apos;negative regulation of receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902161</classIRI>
<classLabel>positive regulation of cyclic nucleotide-gated ion channel activity</classLabel>
<deletedAxiom>&apos;positive regulation of cyclic nucleotide-gated ion channel activity&apos; SubClassOf &apos;positive regulation of receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902427</classIRI>
<classLabel>regulation of water channel activity</classLabel>
<newAxiom>&apos;regulation of water channel activity&apos; SubClassOf &apos;regulation of transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902429</classIRI>
<classLabel>positive regulation of water channel activity</classLabel>
<deletedAxiom>&apos;positive regulation of water channel activity&apos; SubClassOf &apos;positive regulation of transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902428</classIRI>
<classLabel>negative regulation of water channel activity</classLabel>
<deletedAxiom>&apos;negative regulation of water channel activity&apos; SubClassOf &apos;negative regulation of transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902937</classIRI>
<classLabel>inward rectifier potassium channel complex</classLabel>
<deletedAxiom>&apos;inward rectifier potassium channel complex&apos; SubClassOf &apos;plasma membrane receptor complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017071</classIRI>
<classLabel>intracellular cyclic nucleotide activated cation channel complex</classLabel>
<deletedAxiom>&apos;intracellular cyclic nucleotide activated cation channel complex&apos; SubClassOf &apos;receptor complex&apos;</deletedAxiom>
</changedClass>
</changedClasses>
<newClasses>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>