<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
394
</numberChangedClasses>
<numberNewClasses>
21
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019279</classIRI>
<classLabel>L-methionine biosynthetic process from L-homoserine via cystathionine</classLabel>
<newAxiom>&apos;L-methionine biosynthetic process from L-homoserine via cystathionine&apos; SubClassOf &apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_17755</newAxiom>
<newAxiom>&apos;L-methionine biosynthetic process from L-homoserine via cystathionine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_17755) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15699) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16643)</newAxiom>
<newAxiom>&apos;L-methionine biosynthetic process from L-homoserine via cystathionine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15699</newAxiom>
<newAxiom>&apos;L-methionine biosynthetic process from L-homoserine via cystathionine&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16643</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019293</classIRI>
<classLabel>tyrosine biosynthetic process, by oxidation of phenylalanine</classLabel>
<newAxiom>&apos;tyrosine biosynthetic process, by oxidation of phenylalanine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_28044</newAxiom>
<newAxiom>&apos;tyrosine biosynthetic process, by oxidation of phenylalanine&apos; SubClassOf &apos;has_part&apos; some &apos;oxidation-reduction process&apos;</newAxiom>
<newAxiom>&apos;tyrosine biosynthetic process, by oxidation of phenylalanine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has_part&apos; some &apos;oxidation-reduction process&apos;) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_28044) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_18186)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010845</classIRI>
<classLabel>positive regulation of reciprocal meiotic recombination</classLabel>
<deletedAxiom>&apos;positive regulation of reciprocal meiotic recombination&apos; SubClassOf &apos;positive regulation of meiotic nuclear division&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of reciprocal meiotic recombination&apos; SubClassOf &apos;positive regulation of meiosis I&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009884</classIRI>
<classLabel>cytokinin receptor activity</classLabel>
<deletedAxiom>&apos;cytokinin receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/GOCHE_23530)</deletedAxiom>
<newAxiom>&apos;cytokinin receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/GOCHE_23530)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034634</classIRI>
<classLabel>glutathione transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;glutathione transmembrane transporter activity&apos; SubClassOf &apos;oligopeptide transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034551</classIRI>
<classLabel>mitochondrial respiratory chain complex III assembly</classLabel>
<deletedAxiom>&apos;mitochondrial respiratory chain complex III assembly&apos; SubClassOf &apos;mitochondrial respiratory chain complex III biogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034553</classIRI>
<classLabel>mitochondrial respiratory chain complex II assembly</classLabel>
<deletedAxiom>&apos;mitochondrial respiratory chain complex II assembly&apos; SubClassOf &apos;mitochondrial respiratory chain complex II biogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010520</classIRI>
<classLabel>regulation of reciprocal meiotic recombination</classLabel>
<deletedAxiom>&apos;regulation of reciprocal meiotic recombination&apos; SubClassOf &apos;regulation of cell cycle process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of reciprocal meiotic recombination&apos; SubClassOf &apos;regulation of meiotic cell cycle&apos;</deletedAxiom>
<newAxiom>&apos;regulation of reciprocal meiotic recombination&apos; SubClassOf &apos;regulation of meiosis I&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010522</classIRI>
<classLabel>regulation of calcium ion transport into cytosol</classLabel>
<deletedAxiom>&apos;regulation of calcium ion transport into cytosol&apos; SubClassOf &apos;regulation of ion homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;regulation of calcium ion transport into cytosol&apos; SubClassOf &apos;regulation of biological quality&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010523</classIRI>
<classLabel>negative regulation of calcium ion transport into cytosol</classLabel>
<deletedAxiom>&apos;negative regulation of calcium ion transport into cytosol&apos; SubClassOf &apos;negative regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010524</classIRI>
<classLabel>positive regulation of calcium ion transport into cytosol</classLabel>
<deletedAxiom>&apos;positive regulation of calcium ion transport into cytosol&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010469</classIRI>
<classLabel>regulation of receptor activity</classLabel>
<deletedAxiom>&apos;regulation of receptor activity&apos; SubClassOf &apos;regulates&apos; some &apos;receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of receptor activity&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;receptor activity&apos;)</deletedAxiom>
<newAxiom>&apos;regulation of receptor activity&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;signaling receptor activity&apos;)</newAxiom>
<newAxiom>&apos;regulation of receptor activity&apos; SubClassOf &apos;regulates&apos; some &apos;signaling receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009227</classIRI>
<classLabel>nucleotide-sugar catabolic process</classLabel>
<deletedAxiom>&apos;nucleotide-sugar catabolic process&apos; SubClassOf &apos;nucleobase-containing compound catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;nucleotide-sugar catabolic process&apos; SubClassOf &apos;nucleobase-containing small molecule catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009163</classIRI>
<classLabel>nucleoside biosynthetic process</classLabel>
<deletedAxiom>&apos;nucleoside biosynthetic process&apos; SubClassOf &apos;nucleobase-containing compound biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;nucleoside biosynthetic process&apos; SubClassOf &apos;nucleobase-containing small molecule biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009164</classIRI>
<classLabel>nucleoside catabolic process</classLabel>
<deletedAxiom>&apos;nucleoside catabolic process&apos; SubClassOf &apos;nucleobase-containing compound catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;nucleoside catabolic process&apos; SubClassOf &apos;nucleobase-containing small molecule catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034108</classIRI>
<classLabel>positive regulation of erythrocyte clearance</classLabel>
<deletedAxiom>&apos;positive regulation of erythrocyte clearance&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034106</classIRI>
<classLabel>regulation of erythrocyte clearance</classLabel>
<deletedAxiom>&apos;regulation of erythrocyte clearance&apos; SubClassOf &apos;regulation of homeostatic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of erythrocyte clearance&apos; SubClassOf &apos;regulation of biological quality&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034107</classIRI>
<classLabel>negative regulation of erythrocyte clearance</classLabel>
<deletedAxiom>&apos;negative regulation of erythrocyte clearance&apos; SubClassOf &apos;negative regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034188</classIRI>
<classLabel>apolipoprotein A-I receptor activity</classLabel>
<deletedAxiom>&apos;apolipoprotein A-I receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000004140)</deletedAxiom>
<newAxiom>&apos;apolipoprotein A-I receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000004140)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000273</classIRI>
<classLabel>positive regulation of receptor activity</classLabel>
<deletedAxiom>&apos;positive regulation of receptor activity&apos; SubClassOf &apos;positively regulates&apos; some &apos;receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of receptor activity&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;receptor activity&apos;)</deletedAxiom>
<newAxiom>&apos;positive regulation of receptor activity&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;signaling receptor activity&apos;)</newAxiom>
<newAxiom>&apos;positive regulation of receptor activity&apos; SubClassOf &apos;positive regulation of signal transduction&apos;</newAxiom>
<newAxiom>&apos;positive regulation of receptor activity&apos; SubClassOf &apos;positively regulates&apos; some &apos;signaling receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000272</classIRI>
<classLabel>negative regulation of receptor activity</classLabel>
<deletedAxiom>&apos;negative regulation of receptor activity&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of receptor activity&apos; SubClassOf &apos;negatively regulates&apos; some &apos;receptor activity&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of receptor activity&apos; SubClassOf &apos;negative regulation of signal transduction&apos;</newAxiom>
<newAxiom>&apos;negative regulation of receptor activity&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;signaling receptor activity&apos;)</newAxiom>
<newAxiom>&apos;negative regulation of receptor activity&apos; SubClassOf &apos;negatively regulates&apos; some &apos;signaling receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000189</classIRI>
<classLabel>positive regulation of cholesterol homeostasis</classLabel>
<deletedAxiom>&apos;positive regulation of cholesterol homeostasis&apos; SubClassOf &apos;positively regulates&apos; some &apos;cholesterol homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cholesterol homeostasis&apos; SubClassOf &apos;regulation of cholesterol homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cholesterol homeostasis&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cholesterol homeostasis&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;cholesterol homeostasis&apos;)</deletedAxiom>
<newAxiom>&apos;positive regulation of cholesterol homeostasis&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000188</classIRI>
<classLabel>regulation of cholesterol homeostasis</classLabel>
<deletedAxiom>&apos;regulation of cholesterol homeostasis&apos; SubClassOf &apos;regulates&apos; some &apos;cholesterol homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cholesterol homeostasis&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;cholesterol homeostasis&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of cholesterol homeostasis&apos; SubClassOf &apos;regulation of homeostatic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of cholesterol homeostasis&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097472</classIRI>
<classLabel>cyclin-dependent protein kinase activity</classLabel>
<deletedAxiom>&apos;cyclin-dependent protein kinase activity&apos; SubClassOf &apos;molecular transducer activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097430</classIRI>
<classLabel>copper ion import into ascospore-type prospore</classLabel>
<deletedAxiom>&apos;copper ion import into ascospore-type prospore&apos; EquivalentTo &apos;copper ion import&apos; and (&apos;has target end location&apos; some &apos;ascospore-type prospore&apos;)</deletedAxiom>
<deletedAxiom>&apos;copper ion import into ascospore-type prospore&apos; SubClassOf &apos;intracellular copper ion transport&apos;</deletedAxiom>
<newAxiom>&apos;copper ion import into ascospore-type prospore&apos; SubClassOf &apos;results in transport across&apos; some &apos;prospore membrane&apos;</newAxiom>
<newAxiom>&apos;copper ion import into ascospore-type prospore&apos; SubClassOf &apos;has target start location&apos; some &apos;extracellular region&apos;</newAxiom>
<newAxiom>&apos;copper ion import into ascospore-type prospore&apos; EquivalentTo &apos;transport&apos; and (&apos;has target start location&apos; some &apos;extracellular region&apos;) and (&apos;has target end location&apos; some &apos;ascospore-type prospore&apos;) and (&apos;imports&apos; some http://purl.obolibrary.org/obo/CHEBI_23378) and (&apos;results in transport across&apos; some &apos;prospore membrane&apos;)</newAxiom>
<newAxiom>&apos;copper ion import into ascospore-type prospore&apos; SubClassOf &apos;copper ion transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000365</classIRI>
<classLabel>negative regulation of STAT protein import into nucleus</classLabel>
<deletedAxiom>&apos;negative regulation of STAT protein import into nucleus&apos; SubClassOf &apos;regulation of STAT protein import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of STAT protein import into nucleus&apos; SubClassOf &apos;negative regulation of JAK-STAT cascade&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of STAT protein import into nucleus&apos; SubClassOf &apos;negative regulation of protein import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of STAT protein import into nucleus&apos; SubClassOf &apos;negatively regulates&apos; some &apos;STAT protein import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of STAT protein import into nucleus&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;STAT protein import into nucleus&apos;)</deletedAxiom>
<newAxiom>&apos;negative regulation of STAT protein import into nucleus&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000366</classIRI>
<classLabel>positive regulation of STAT protein import into nucleus</classLabel>
<deletedAxiom>&apos;positive regulation of STAT protein import into nucleus&apos; SubClassOf &apos;positive regulation of protein import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of STAT protein import into nucleus&apos; SubClassOf &apos;positively regulates&apos; some &apos;STAT protein import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of STAT protein import into nucleus&apos; SubClassOf &apos;positive regulation of JAK-STAT cascade&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of STAT protein import into nucleus&apos; SubClassOf &apos;regulation of STAT protein import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of STAT protein import into nucleus&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;STAT protein import into nucleus&apos;)</deletedAxiom>
<newAxiom>&apos;positive regulation of STAT protein import into nucleus&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000364</classIRI>
<classLabel>regulation of STAT protein import into nucleus</classLabel>
<deletedAxiom>&apos;regulation of STAT protein import into nucleus&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;STAT protein import into nucleus&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of STAT protein import into nucleus&apos; SubClassOf &apos;regulates&apos; some &apos;STAT protein import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of STAT protein import into nucleus&apos; SubClassOf &apos;regulation of protein import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of STAT protein import into nucleus&apos; SubClassOf &apos;regulation of JAK-STAT cascade&apos;</deletedAxiom>
<newAxiom>&apos;regulation of STAT protein import into nucleus&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097253</classIRI>
<classLabel>beta-hydroxybutyrate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;beta-hydroxybutyrate transmembrane transporter activity&apos; SubClassOf &apos;monocarboxylic acid transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990134</classIRI>
<classLabel>epithelial cell apoptotic process involved in palatal shelf morphogenesis</classLabel>
<deletedAxiom>&apos;epithelial cell apoptotic process involved in palatal shelf morphogenesis&apos; SubClassOf &apos;part of&apos; some &apos;palate development&apos;</deletedAxiom>
<newAxiom>&apos;epithelial cell apoptotic process involved in palatal shelf morphogenesis&apos; SubClassOf &apos;part of&apos; some http://purl.obolibrary.org/obo/GO_0062009</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048018</classIRI>
<classLabel>receptor ligand activity</classLabel>
<deletedAxiom>&apos;receptor ligand activity&apos; SubClassOf &apos;directly regulates&apos; some &apos;signaling receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990081</classIRI>
<classLabel>trimethylamine receptor activity</classLabel>
<deletedAxiom>&apos;trimethylamine receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18139)</deletedAxiom>
<newAxiom>&apos;trimethylamine receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18139)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990080</classIRI>
<classLabel>2-phenylethylamine receptor activity</classLabel>
<deletedAxiom>&apos;2-phenylethylamine receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18397)</deletedAxiom>
<newAxiom>&apos;2-phenylethylamine receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18397)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000507</classIRI>
<classLabel>positive regulation of energy homeostasis</classLabel>
<deletedAxiom>&apos;positive regulation of energy homeostasis&apos; SubClassOf &apos;positively regulates&apos; some &apos;energy homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of energy homeostasis&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;energy homeostasis&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of energy homeostasis&apos; SubClassOf &apos;positive regulation of multicellular organismal process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of energy homeostasis&apos; SubClassOf &apos;regulation of energy homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of energy homeostasis&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of energy homeostasis&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000505</classIRI>
<classLabel>regulation of energy homeostasis</classLabel>
<deletedAxiom>&apos;regulation of energy homeostasis&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;energy homeostasis&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of energy homeostasis&apos; SubClassOf &apos;regulation of homeostatic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of energy homeostasis&apos; SubClassOf &apos;regulation of multicellular organismal process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of energy homeostasis&apos; SubClassOf &apos;regulates&apos; some &apos;energy homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;regulation of energy homeostasis&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000506</classIRI>
<classLabel>negative regulation of energy homeostasis</classLabel>
<deletedAxiom>&apos;negative regulation of energy homeostasis&apos; SubClassOf &apos;negative regulation of homeostatic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of energy homeostasis&apos; SubClassOf &apos;regulation of energy homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of energy homeostasis&apos; SubClassOf &apos;negatively regulates&apos; some &apos;energy homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of energy homeostasis&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;energy homeostasis&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of energy homeostasis&apos; SubClassOf &apos;negative regulation of multicellular organismal process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of energy homeostasis&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097031</classIRI>
<classLabel>mitochondrial respiratory chain complex I biogenesis</classLabel>
<deletedAxiom>&apos;mitochondrial respiratory chain complex I biogenesis&apos; SubClassOf &apos;protein complex biogenesis&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial respiratory chain complex I biogenesis&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097032</classIRI>
<classLabel>mitochondrial respiratory chain complex II biogenesis</classLabel>
<deletedAxiom>&apos;mitochondrial respiratory chain complex II biogenesis&apos; SubClassOf &apos;protein complex biogenesis&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial respiratory chain complex II biogenesis&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097033</classIRI>
<classLabel>mitochondrial respiratory chain complex III biogenesis</classLabel>
<deletedAxiom>&apos;mitochondrial respiratory chain complex III biogenesis&apos; SubClassOf &apos;protein complex biogenesis&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial respiratory chain complex III biogenesis&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097034</classIRI>
<classLabel>mitochondrial respiratory chain complex IV biogenesis</classLabel>
<deletedAxiom>&apos;mitochondrial respiratory chain complex IV biogenesis&apos; SubClassOf &apos;protein complex biogenesis&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial respiratory chain complex IV biogenesis&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990272</classIRI>
<classLabel>anti-Mullerian hormone receptor activity</classLabel>
<deletedAxiom>&apos;anti-Mullerian hormone receptor activity&apos; SubClassOf &apos;signaling receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004900</classIRI>
<classLabel>erythropoietin receptor activity</classLabel>
<deletedAxiom>&apos;erythropoietin receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000007141)</deletedAxiom>
<newAxiom>&apos;erythropoietin receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000007141)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004901</classIRI>
<classLabel>granulocyte macrophage colony-stimulating factor receptor activity</classLabel>
<deletedAxiom>&apos;granulocyte macrophage colony-stimulating factor receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000005931)</deletedAxiom>
<newAxiom>&apos;granulocyte macrophage colony-stimulating factor receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000005931)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004902</classIRI>
<classLabel>granulocyte colony-stimulating factor receptor activity</classLabel>
<deletedAxiom>&apos;granulocyte colony-stimulating factor receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000005932)</deletedAxiom>
<newAxiom>&apos;granulocyte colony-stimulating factor receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000005932)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004903</classIRI>
<classLabel>growth hormone receptor activity</classLabel>
<deletedAxiom>&apos;growth hormone receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/GOCHE_37845)</deletedAxiom>
<newAxiom>&apos;growth hormone receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/GOCHE_37845)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004908</classIRI>
<classLabel>interleukin-1 receptor activity</classLabel>
<deletedAxiom>&apos;interleukin-1 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001091)</deletedAxiom>
<newAxiom>&apos;interleukin-1 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001091)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004911</classIRI>
<classLabel>interleukin-2 receptor activity</classLabel>
<deletedAxiom>&apos;interleukin-2 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001379)</deletedAxiom>
<newAxiom>&apos;interleukin-2 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001379)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004912</classIRI>
<classLabel>interleukin-3 receptor activity</classLabel>
<deletedAxiom>&apos;interleukin-3 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001387)</deletedAxiom>
<newAxiom>&apos;interleukin-3 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001387)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004913</classIRI>
<classLabel>interleukin-4 receptor activity</classLabel>
<deletedAxiom>&apos;interleukin-4 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001391)</deletedAxiom>
<newAxiom>&apos;interleukin-4 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001391)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004914</classIRI>
<classLabel>interleukin-5 receptor activity</classLabel>
<deletedAxiom>&apos;interleukin-5 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001392)</deletedAxiom>
<newAxiom>&apos;interleukin-5 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001392)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004915</classIRI>
<classLabel>interleukin-6 receptor activity</classLabel>
<deletedAxiom>&apos;interleukin-6 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001393)</deletedAxiom>
<newAxiom>&apos;interleukin-6 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001393)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004917</classIRI>
<classLabel>interleukin-7 receptor activity</classLabel>
<deletedAxiom>&apos;interleukin-7 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001317)</deletedAxiom>
<newAxiom>&apos;interleukin-7 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001317)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004918</classIRI>
<classLabel>interleukin-8 receptor activity</classLabel>
<deletedAxiom>&apos;interleukin-8 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001395)</deletedAxiom>
<newAxiom>&apos;interleukin-8 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001395)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004919</classIRI>
<classLabel>interleukin-9 receptor activity</classLabel>
<deletedAxiom>&apos;interleukin-9 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001396)</deletedAxiom>
<newAxiom>&apos;interleukin-9 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001396)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004920</classIRI>
<classLabel>interleukin-10 receptor activity</classLabel>
<deletedAxiom>&apos;interleukin-10 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001471)</deletedAxiom>
<newAxiom>&apos;interleukin-10 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001471)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004921</classIRI>
<classLabel>interleukin-11 receptor activity</classLabel>
<deletedAxiom>&apos;interleukin-11 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001366)</deletedAxiom>
<newAxiom>&apos;interleukin-11 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001366)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004923</classIRI>
<classLabel>leukemia inhibitory factor receptor activity</classLabel>
<deletedAxiom>&apos;leukemia inhibitory factor receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000009799)</deletedAxiom>
<newAxiom>&apos;leukemia inhibitory factor receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000009799)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004924</classIRI>
<classLabel>oncostatin-M receptor activity</classLabel>
<deletedAxiom>&apos;oncostatin-M receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000012059)</deletedAxiom>
<newAxiom>&apos;oncostatin-M receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000012059)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004925</classIRI>
<classLabel>prolactin receptor activity</classLabel>
<deletedAxiom>&apos;prolactin receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000013246)</deletedAxiom>
<newAxiom>&apos;prolactin receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000013246)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004947</classIRI>
<classLabel>bradykinin receptor activity</classLabel>
<deletedAxiom>&apos;bradykinin receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_3165)</deletedAxiom>
<newAxiom>&apos;bradykinin receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_3165)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004948</classIRI>
<classLabel>calcitonin receptor activity</classLabel>
<deletedAxiom>&apos;calcitonin receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_3306)</deletedAxiom>
<newAxiom>&apos;calcitonin receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_3306)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004949</classIRI>
<classLabel>cannabinoid receptor activity</classLabel>
<deletedAxiom>&apos;cannabinoid receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_67194)</deletedAxiom>
<newAxiom>&apos;cannabinoid receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_67194)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004951</classIRI>
<classLabel>cholecystokinin receptor activity</classLabel>
<deletedAxiom>&apos;cholecystokinin receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000005110)</deletedAxiom>
<newAxiom>&apos;cholecystokinin receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000005110)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004953</classIRI>
<classLabel>icosanoid receptor activity</classLabel>
<deletedAxiom>&apos;icosanoid receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_23899)</deletedAxiom>
<newAxiom>&apos;icosanoid receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_23899)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004954</classIRI>
<classLabel>prostanoid receptor activity</classLabel>
<deletedAxiom>&apos;prostanoid receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_26347)</deletedAxiom>
<newAxiom>&apos;prostanoid receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_26347)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004955</classIRI>
<classLabel>prostaglandin receptor activity</classLabel>
<deletedAxiom>&apos;prostaglandin receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_26333)</deletedAxiom>
<newAxiom>&apos;prostaglandin receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_26333)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004956</classIRI>
<classLabel>prostaglandin D receptor activity</classLabel>
<deletedAxiom>&apos;prostaglandin D receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_26337)</deletedAxiom>
<newAxiom>&apos;prostaglandin D receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_26337)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004957</classIRI>
<classLabel>prostaglandin E receptor activity</classLabel>
<deletedAxiom>&apos;prostaglandin E receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_26338)</deletedAxiom>
<newAxiom>&apos;prostaglandin E receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_26338)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004958</classIRI>
<classLabel>prostaglandin F receptor activity</classLabel>
<deletedAxiom>&apos;prostaglandin F receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_26340)</deletedAxiom>
<newAxiom>&apos;prostaglandin F receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_26340)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004960</classIRI>
<classLabel>thromboxane receptor activity</classLabel>
<deletedAxiom>&apos;thromboxane receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_26995)</deletedAxiom>
<newAxiom>&apos;thromboxane receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_26995)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004961</classIRI>
<classLabel>thromboxane A2 receptor activity</classLabel>
<deletedAxiom>&apos;thromboxane A2 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15627)</deletedAxiom>
<newAxiom>&apos;thromboxane A2 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15627)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004963</classIRI>
<classLabel>follicle-stimulating hormone receptor activity</classLabel>
<deletedAxiom>&apos;follicle-stimulating hormone receptor activity&apos; SubClassOf &apos;signaling receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004966</classIRI>
<classLabel>galanin receptor activity</classLabel>
<deletedAxiom>&apos;galanin receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000007806)</deletedAxiom>
<newAxiom>&apos;galanin receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000007806)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004967</classIRI>
<classLabel>glucagon receptor activity</classLabel>
<deletedAxiom>&apos;glucagon receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_5391)</deletedAxiom>
<newAxiom>&apos;glucagon receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_5391)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004969</classIRI>
<classLabel>histamine receptor activity</classLabel>
<deletedAxiom>&apos;histamine receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18295)</deletedAxiom>
<newAxiom>&apos;histamine receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18295)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004974</classIRI>
<classLabel>leukotriene receptor activity</classLabel>
<deletedAxiom>&apos;leukotriene receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_25029)</deletedAxiom>
<newAxiom>&apos;leukotriene receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_25029)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004978</classIRI>
<classLabel>corticotropin receptor activity</classLabel>
<deletedAxiom>&apos;corticotropin receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_3892)</deletedAxiom>
<newAxiom>&apos;corticotropin receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_3892)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004979</classIRI>
<classLabel>beta-endorphin receptor activity</classLabel>
<deletedAxiom>&apos;beta-endorphin receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_10415)</deletedAxiom>
<newAxiom>&apos;beta-endorphin receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_10415)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004983</classIRI>
<classLabel>neuropeptide Y receptor activity</classLabel>
<deletedAxiom>&apos;neuropeptide Y receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000011387)</deletedAxiom>
<newAxiom>&apos;neuropeptide Y receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000011387)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004989</classIRI>
<classLabel>octopamine receptor activity</classLabel>
<deletedAxiom>&apos;octopamine receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17134)</deletedAxiom>
<newAxiom>&apos;octopamine receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17134)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004990</classIRI>
<classLabel>oxytocin receptor activity</classLabel>
<deletedAxiom>&apos;oxytocin receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_7872)</deletedAxiom>
<newAxiom>&apos;oxytocin receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_7872)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004991</classIRI>
<classLabel>parathyroid hormone receptor activity</classLabel>
<deletedAxiom>&apos;parathyroid hormone receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000013429)</deletedAxiom>
<newAxiom>&apos;parathyroid hormone receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000013429)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004992</classIRI>
<classLabel>platelet activating factor receptor activity</classLabel>
<deletedAxiom>&apos;platelet activating factor receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_52450)</deletedAxiom>
<newAxiom>&apos;platelet activating factor receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_52450)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004994</classIRI>
<classLabel>somatostatin receptor activity</classLabel>
<deletedAxiom>&apos;somatostatin receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_64628)</deletedAxiom>
<newAxiom>&apos;somatostatin receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_64628)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004996</classIRI>
<classLabel>thyroid-stimulating hormone receptor activity</classLabel>
<deletedAxiom>&apos;thyroid-stimulating hormone receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000028269)</deletedAxiom>
<newAxiom>&apos;thyroid-stimulating hormone receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000028269)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004998</classIRI>
<classLabel>transferrin receptor activity</classLabel>
<deletedAxiom>&apos;transferrin receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000016261)</deletedAxiom>
<newAxiom>&apos;transferrin receptor activity&apos; EquivalentTo &apos;cargo receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000016261)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004872</classIRI>
<classLabel>receptor activity</classLabel>
<deletedAxiom>&apos;receptor activity&apos; SubClassOf &apos;molecular transducer activity&apos;</deletedAxiom>
<newAxiom>&apos;receptor activity&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004880</classIRI>
<classLabel>juvenile hormone receptor activity</classLabel>
<deletedAxiom>&apos;juvenile hormone receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_24943)</deletedAxiom>
<newAxiom>&apos;juvenile hormone receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_24943)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004882</classIRI>
<classLabel>androgen receptor activity</classLabel>
<deletedAxiom>&apos;androgen receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_50113)</deletedAxiom>
<newAxiom>&apos;androgen receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_50113)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004883</classIRI>
<classLabel>glucocorticoid receptor activity</classLabel>
<deletedAxiom>&apos;glucocorticoid receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_24261)</deletedAxiom>
<newAxiom>&apos;glucocorticoid receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_24261)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004884</classIRI>
<classLabel>ecdysteroid hormone receptor activity</classLabel>
<deletedAxiom>&apos;ecdysteroid hormone receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_23897)</deletedAxiom>
<newAxiom>&apos;ecdysteroid hormone receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_23897)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004887</classIRI>
<classLabel>thyroid hormone receptor activity</classLabel>
<deletedAxiom>&apos;thyroid hormone receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/GOCHE_60311)</deletedAxiom>
<newAxiom>&apos;thyroid hormone receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/GOCHE_60311)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004888</classIRI>
<classLabel>transmembrane signaling receptor activity</classLabel>
<deletedAxiom>&apos;transmembrane signaling receptor activity&apos; EquivalentTo &apos;transmembrane receptor activity&apos; and (&apos;part of&apos; some &apos;signal transduction&apos;)</deletedAxiom>
<deletedAxiom>&apos;transmembrane signaling receptor activity&apos; SubClassOf &apos;transmembrane receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004897</classIRI>
<classLabel>ciliary neurotrophic factor receptor activity</classLabel>
<deletedAxiom>&apos;ciliary neurotrophic factor receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000005663)</deletedAxiom>
<newAxiom>&apos;ciliary neurotrophic factor receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000005663)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038149</classIRI>
<classLabel>C-C motif chemokine 2 receptor activity</classLabel>
<deletedAxiom>&apos;C-C motif chemokine 2 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000002122)</deletedAxiom>
<newAxiom>&apos;C-C motif chemokine 2 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000002122)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038187</classIRI>
<classLabel>pattern recognition receptor activity</classLabel>
<deletedAxiom>&apos;pattern recognition receptor activity&apos; SubClassOf &apos;receptor activity&apos;</deletedAxiom>
<newAxiom>&apos;pattern recognition receptor activity&apos; SubClassOf &apos;signaling receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038198</classIRI>
<classLabel>auxin receptor activity</classLabel>
<deletedAxiom>&apos;auxin receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/GOCHE_22676)</deletedAxiom>
<newAxiom>&apos;auxin receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/GOCHE_22676)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038199</classIRI>
<classLabel>ethylene receptor activity</classLabel>
<deletedAxiom>&apos;ethylene receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18153)</deletedAxiom>
<newAxiom>&apos;ethylene receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18153)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004690</classIRI>
<classLabel>cyclic nucleotide-dependent protein kinase activity</classLabel>
<deletedAxiom>&apos;cyclic nucleotide-dependent protein kinase activity&apos; SubClassOf &apos;molecular transducer activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038023</classIRI>
<classLabel>signaling receptor activity</classLabel>
<deletedAxiom>&apos;signaling receptor activity&apos; SubClassOf &apos;signal transducer activity&apos;</deletedAxiom>
<deletedAxiom>&apos;signaling receptor activity&apos; SubClassOf &apos;receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;signaling receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;part of&apos; some &apos;signal transduction&apos;)</deletedAxiom>
<newAxiom>&apos;signaling receptor activity&apos; SubClassOf &apos;molecular transducer activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038024</classIRI>
<classLabel>cargo receptor activity</classLabel>
<deletedAxiom>&apos;cargo receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;part of&apos; some &apos;receptor-mediated endocytosis&apos;)</deletedAxiom>
<deletedAxiom>&apos;cargo receptor activity&apos; SubClassOf &apos;receptor activity&apos;</deletedAxiom>
<newAxiom>&apos;cargo receptor activity&apos; SubClassOf &apos;molecular_function&apos;</newAxiom>
<newAxiom>&apos;cargo receptor activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;part of&apos; some &apos;receptor-mediated endocytosis&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038047</classIRI>
<classLabel>morphine receptor activity</classLabel>
<deletedAxiom>&apos;morphine receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17303)</deletedAxiom>
<newAxiom>&apos;morphine receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17303)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038036</classIRI>
<classLabel>sphingosine-1-phosphate receptor activity</classLabel>
<deletedAxiom>&apos;sphingosine-1-phosphate receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_37550)</deletedAxiom>
<newAxiom>&apos;sphingosine-1-phosphate receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_37550)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004679</classIRI>
<classLabel>AMP-activated protein kinase activity</classLabel>
<deletedAxiom>&apos;AMP-activated protein kinase activity&apos; SubClassOf &apos;molecular transducer activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004467</classIRI>
<classLabel>long-chain fatty acid-CoA ligase activity</classLabel>
<newAxiom>&apos;long-chain fatty acid-CoA ligase activity&apos; SubClassOf &apos;CoA-ligase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000021</classIRI>
<classLabel>regulation of ion homeostasis</classLabel>
<deletedAxiom>&apos;regulation of ion homeostasis&apos; SubClassOf &apos;regulates&apos; some &apos;ion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of ion homeostasis&apos; SubClassOf &apos;regulation of homeostatic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of ion homeostasis&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;ion homeostasis&apos;)</deletedAxiom>
<newAxiom>&apos;regulation of ion homeostasis&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901292</classIRI>
<classLabel>nucleoside phosphate catabolic process</classLabel>
<newAxiom>&apos;nucleoside phosphate catabolic process&apos; SubClassOf &apos;nucleobase-containing small molecule biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901546</classIRI>
<classLabel>regulation of synaptic vesicle lumen acidification</classLabel>
<deletedAxiom>&apos;regulation of synaptic vesicle lumen acidification&apos; SubClassOf &apos;regulation of homeostatic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of synaptic vesicle lumen acidification&apos; SubClassOf &apos;regulation of biological quality&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901547</classIRI>
<classLabel>negative regulation of synaptic vesicle lumen acidification</classLabel>
<deletedAxiom>&apos;negative regulation of synaptic vesicle lumen acidification&apos; SubClassOf &apos;negative regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901548</classIRI>
<classLabel>positive regulation of synaptic vesicle lumen acidification</classLabel>
<deletedAxiom>&apos;positive regulation of synaptic vesicle lumen acidification&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901584</classIRI>
<classLabel>tetrapeptide transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;tetrapeptide transmembrane transporter activity&apos; EquivalentTo &apos;transmembrane transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_48030)</deletedAxiom>
<newAxiom>&apos;tetrapeptide transmembrane transporter activity&apos; EquivalentTo &apos;transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_48030) and (&apos;results in transport across&apos; some &apos;membrane&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901480</classIRI>
<classLabel>oleate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;oleate transmembrane transporter activity&apos; SubClassOf &apos;monocarboxylic acid transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;oleate transmembrane transporter activity&apos; SubClassOf &apos;fatty acid transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102391</classIRI>
<classLabel>decanoate-CoA ligase activity</classLabel>
<deletedAxiom>&apos;decanoate-CoA ligase activity&apos; SubClassOf &apos;CoA-ligase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;decanoate-CoA ligase activity&apos; SubClassOf &apos;acid-thiol ligase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043404</classIRI>
<classLabel>corticotropin-releasing hormone receptor activity</classLabel>
<deletedAxiom>&apos;corticotropin-releasing hormone receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_65311)</deletedAxiom>
<newAxiom>&apos;corticotropin-releasing hormone receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_65311)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043461</classIRI>
<classLabel>proton-transporting ATP synthase complex assembly</classLabel>
<deletedAxiom>&apos;proton-transporting ATP synthase complex assembly&apos; SubClassOf &apos;part of&apos; some &apos;proton-transporting ATP synthase complex biogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043466</classIRI>
<classLabel>pyrimidine nucleobase fermentation</classLabel>
<newAxiom>&apos;pyrimidine nucleobase fermentation&apos; EquivalentTo &apos;fermentation&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_26432)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102214</classIRI>
<classLabel>omega-hydroxy fatty acyl-CoA synthetase activity.</classLabel>
<newAxiom>&apos;omega-hydroxy fatty acyl-CoA synthetase activity.&apos; SubClassOf &apos;CoA-ligase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102213</classIRI>
<classLabel>in-chain hydroxy fatty acyl-CoA synthetase activity</classLabel>
<newAxiom>&apos;in-chain hydroxy fatty acyl-CoA synthetase activity&apos; SubClassOf &apos;CoA-ligase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008922</classIRI>
<classLabel>long-chain fatty acid [acyl-carrier-protein] ligase activity</classLabel>
<deletedAxiom>&apos;long-chain fatty acid [acyl-carrier-protein] ligase activity&apos; SubClassOf &apos;acid-thiol ligase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043235</classIRI>
<classLabel>receptor complex</classLabel>
<deletedAxiom>&apos;receptor complex&apos; SubClassOf &apos;capable of&apos; some &apos;receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;receptor complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;capable of&apos; some &apos;receptor activity&apos;)</deletedAxiom>
<newAxiom>&apos;receptor complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;capable of&apos; some &apos;signaling receptor activity&apos;)</newAxiom>
<newAxiom>&apos;receptor complex&apos; SubClassOf &apos;capable of&apos; some &apos;signaling receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033617</classIRI>
<classLabel>mitochondrial respiratory chain complex IV assembly</classLabel>
<deletedAxiom>&apos;mitochondrial respiratory chain complex IV assembly&apos; SubClassOf &apos;mitochondrial respiratory chain complex IV biogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070506</classIRI>
<classLabel>high-density lipoprotein particle receptor activity</classLabel>
<newAxiom>&apos;high-density lipoprotein particle receptor activity&apos; SubClassOf &apos;has input&apos; some &apos;high-density lipoprotein particle&apos;</newAxiom>
<newAxiom>&apos;high-density lipoprotein particle receptor activity&apos; EquivalentTo &apos;cargo receptor activity&apos; and (&apos;has input&apos; some &apos;high-density lipoprotein particle&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070553</classIRI>
<classLabel>nicotinic acid receptor activity</classLabel>
<deletedAxiom>&apos;nicotinic acid receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15940)</deletedAxiom>
<newAxiom>&apos;nicotinic acid receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15940)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045506</classIRI>
<classLabel>interleukin-24 receptor activity</classLabel>
<deletedAxiom>&apos;interleukin-24 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001474)</deletedAxiom>
<newAxiom>&apos;interleukin-24 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001474)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045507</classIRI>
<classLabel>interleukin-25 receptor activity</classLabel>
<deletedAxiom>&apos;interleukin-25 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001113)</deletedAxiom>
<newAxiom>&apos;interleukin-25 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001113)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045508</classIRI>
<classLabel>interleukin-26 receptor activity</classLabel>
<deletedAxiom>&apos;interleukin-26 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001475)</deletedAxiom>
<newAxiom>&apos;interleukin-26 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001475)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045509</classIRI>
<classLabel>interleukin-27 receptor activity</classLabel>
<deletedAxiom>&apos;interleukin-27 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001141)</deletedAxiom>
<newAxiom>&apos;interleukin-27 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001141)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070235</classIRI>
<classLabel>regulation of activation-induced cell death of T cells</classLabel>
<deletedAxiom>&apos;regulation of activation-induced cell death of T cells&apos; SubClassOf &apos;regulation of homeostatic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of activation-induced cell death of T cells&apos; SubClassOf &apos;regulation of biological quality&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070236</classIRI>
<classLabel>negative regulation of activation-induced cell death of T cells</classLabel>
<deletedAxiom>&apos;negative regulation of activation-induced cell death of T cells&apos; SubClassOf &apos;negative regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070237</classIRI>
<classLabel>positive regulation of activation-induced cell death of T cells</classLabel>
<deletedAxiom>&apos;positive regulation of activation-induced cell death of T cells&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070239</classIRI>
<classLabel>regulation of activated T cell autonomous cell death</classLabel>
<deletedAxiom>&apos;regulation of activated T cell autonomous cell death&apos; SubClassOf &apos;regulation of homeostatic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of activated T cell autonomous cell death&apos; SubClassOf &apos;regulation of biological quality&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070240</classIRI>
<classLabel>negative regulation of activated T cell autonomous cell death</classLabel>
<deletedAxiom>&apos;negative regulation of activated T cell autonomous cell death&apos; SubClassOf &apos;negative regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070271</classIRI>
<classLabel>protein complex biogenesis</classLabel>
<deletedAxiom>&apos;protein complex biogenesis&apos; SubClassOf &apos;cellular component biogenesis&apos;</deletedAxiom>
<newAxiom>&apos;protein complex biogenesis&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070272</classIRI>
<classLabel>proton-transporting ATP synthase complex biogenesis</classLabel>
<deletedAxiom>&apos;proton-transporting ATP synthase complex biogenesis&apos; SubClassOf &apos;protein complex biogenesis&apos;</deletedAxiom>
<newAxiom>&apos;proton-transporting ATP synthase complex biogenesis&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070241</classIRI>
<classLabel>positive regulation of activated T cell autonomous cell death</classLabel>
<deletedAxiom>&apos;positive regulation of activated T cell autonomous cell death&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035813</classIRI>
<classLabel>regulation of renal sodium excretion</classLabel>
<deletedAxiom>&apos;regulation of renal sodium excretion&apos; SubClassOf &apos;regulation of ion homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;regulation of renal sodium excretion&apos; SubClassOf &apos;regulation of biological quality&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035814</classIRI>
<classLabel>negative regulation of renal sodium excretion</classLabel>
<deletedAxiom>&apos;negative regulation of renal sodium excretion&apos; SubClassOf &apos;negative regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035815</classIRI>
<classLabel>positive regulation of renal sodium excretion</classLabel>
<deletedAxiom>&apos;positive regulation of renal sodium excretion&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035774</classIRI>
<classLabel>positive regulation of insulin secretion involved in cellular response to glucose stimulus</classLabel>
<deletedAxiom>&apos;positive regulation of insulin secretion involved in cellular response to glucose stimulus&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035786</classIRI>
<classLabel>protein complex oligomerization</classLabel>
<deletedAxiom>&apos;protein complex oligomerization&apos; SubClassOf &apos;protein-containing complex assembly&apos;</deletedAxiom>
<newAxiom>&apos;protein complex oligomerization&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045128</classIRI>
<classLabel>negative regulation of reciprocal meiotic recombination</classLabel>
<deletedAxiom>&apos;negative regulation of reciprocal meiotic recombination&apos; SubClassOf &apos;negative regulation of meiotic nuclear division&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of reciprocal meiotic recombination&apos; SubClassOf &apos;negative regulation of meiosis I&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045124</classIRI>
<classLabel>regulation of bone resorption</classLabel>
<deletedAxiom>&apos;regulation of bone resorption&apos; SubClassOf &apos;regulation of homeostatic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of bone resorption&apos; SubClassOf &apos;regulation of biological quality&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060730</classIRI>
<classLabel>regulation of intestinal epithelial structure maintenance</classLabel>
<deletedAxiom>&apos;regulation of intestinal epithelial structure maintenance&apos; SubClassOf &apos;regulation of homeostatic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of intestinal epithelial structure maintenance&apos; SubClassOf &apos;regulation of biological quality&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060731</classIRI>
<classLabel>positive regulation of intestinal epithelial structure maintenance</classLabel>
<deletedAxiom>&apos;positive regulation of intestinal epithelial structure maintenance&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035643</classIRI>
<classLabel>L-DOPA receptor activity</classLabel>
<deletedAxiom>&apos;L-DOPA receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15765)</deletedAxiom>
<newAxiom>&apos;L-DOPA receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15765)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035673</classIRI>
<classLabel>oligopeptide transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;oligopeptide transmembrane transporter activity&apos; EquivalentTo &apos;transmembrane transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_25676)</deletedAxiom>
<newAxiom>&apos;oligopeptide transmembrane transporter activity&apos; EquivalentTo &apos;transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_25676) and (&apos;results in transport across&apos; some &apos;membrane&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035413</classIRI>
<classLabel>positive regulation of catenin import into nucleus</classLabel>
<deletedAxiom>&apos;positive regulation of catenin import into nucleus&apos; SubClassOf &apos;regulation of catenin import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of catenin import into nucleus&apos; SubClassOf &apos;positive regulation of protein import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of catenin import into nucleus&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;catenin import into nucleus&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of catenin import into nucleus&apos; SubClassOf &apos;positively regulates&apos; some &apos;catenin import into nucleus&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of catenin import into nucleus&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035414</classIRI>
<classLabel>negative regulation of catenin import into nucleus</classLabel>
<deletedAxiom>&apos;negative regulation of catenin import into nucleus&apos; SubClassOf &apos;negative regulation of protein import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of catenin import into nucleus&apos; SubClassOf &apos;negatively regulates&apos; some &apos;catenin import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of catenin import into nucleus&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;catenin import into nucleus&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of catenin import into nucleus&apos; SubClassOf &apos;regulation of catenin import into nucleus&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of catenin import into nucleus&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035411</classIRI>
<classLabel>catenin import into nucleus</classLabel>
<deletedAxiom>&apos;catenin import into nucleus&apos; SubClassOf &apos;protein import into nucleus&apos;</deletedAxiom>
<newAxiom>&apos;catenin import into nucleus&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035412</classIRI>
<classLabel>regulation of catenin import into nucleus</classLabel>
<deletedAxiom>&apos;regulation of catenin import into nucleus&apos; SubClassOf &apos;regulates&apos; some &apos;catenin import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of catenin import into nucleus&apos; SubClassOf &apos;regulation of protein import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of catenin import into nucleus&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;catenin import into nucleus&apos;)</deletedAxiom>
<newAxiom>&apos;regulation of catenin import into nucleus&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060390</classIRI>
<classLabel>regulation of SMAD protein import into nucleus</classLabel>
<deletedAxiom>&apos;regulation of SMAD protein import into nucleus&apos; SubClassOf &apos;regulation of protein import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of SMAD protein import into nucleus&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;SMAD protein import into nucleus&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of SMAD protein import into nucleus&apos; SubClassOf &apos;regulates&apos; some &apos;SMAD protein import into nucleus&apos;</deletedAxiom>
<newAxiom>&apos;regulation of SMAD protein import into nucleus&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;SMAD protein signal transduction&apos;)</newAxiom>
<newAxiom>&apos;regulation of SMAD protein import into nucleus&apos; SubClassOf &apos;regulates&apos; some &apos;SMAD protein signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060391</classIRI>
<classLabel>positive regulation of SMAD protein import into nucleus</classLabel>
<deletedAxiom>&apos;positive regulation of SMAD protein import into nucleus&apos; SubClassOf &apos;positively regulates&apos; some &apos;SMAD protein import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of SMAD protein import into nucleus&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;SMAD protein import into nucleus&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of SMAD protein import into nucleus&apos; SubClassOf &apos;positive regulation of protein import into nucleus&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of SMAD protein import into nucleus&apos; SubClassOf &apos;positively regulates&apos; some &apos;SMAD protein signal transduction&apos;</newAxiom>
<newAxiom>&apos;positive regulation of SMAD protein import into nucleus&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;SMAD protein signal transduction&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060392</classIRI>
<classLabel>negative regulation of SMAD protein import into nucleus</classLabel>
<deletedAxiom>&apos;negative regulation of SMAD protein import into nucleus&apos; SubClassOf &apos;negative regulation of protein import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of SMAD protein import into nucleus&apos; SubClassOf &apos;negatively regulates&apos; some &apos;SMAD protein import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of SMAD protein import into nucleus&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;SMAD protein import into nucleus&apos;)</deletedAxiom>
<newAxiom>&apos;negative regulation of SMAD protein import into nucleus&apos; SubClassOf &apos;negatively regulates&apos; some &apos;SMAD protein signal transduction&apos;</newAxiom>
<newAxiom>&apos;negative regulation of SMAD protein import into nucleus&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;SMAD protein signal transduction&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098802</classIRI>
<classLabel>plasma membrane receptor complex</classLabel>
<deletedAxiom>&apos;plasma membrane receptor complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;part of&apos; some &apos;plasma membrane&apos;) and (&apos;capable of&apos; some &apos;receptor activity&apos;)</deletedAxiom>
<newAxiom>&apos;plasma membrane receptor complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;part of&apos; some &apos;plasma membrane&apos;) and (&apos;capable of&apos; some &apos;signaling receptor activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098748</classIRI>
<classLabel>endocytic adaptor activity</classLabel>
<deletedAxiom>&apos;endocytic adaptor activity&apos; SubClassOf &apos;part of&apos; some &apos;receptor-mediated endocytosis&apos;</deletedAxiom>
<newAxiom>&apos;endocytic adaptor activity&apos; SubClassOf &apos;cargo receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060175</classIRI>
<classLabel>brain-derived neurotrophic factor-activated receptor activity</classLabel>
<deletedAxiom>&apos;brain-derived neurotrophic factor-activated receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000004716)</deletedAxiom>
<newAxiom>&apos;brain-derived neurotrophic factor-activated receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000004716)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060182</classIRI>
<classLabel>apelin receptor activity</classLabel>
<deletedAxiom>&apos;apelin receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000004135)</deletedAxiom>
<newAxiom>&apos;apelin receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000004135)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001877</classIRI>
<classLabel>lipoarabinomannan receptor activity</classLabel>
<deletedAxiom>&apos;lipoarabinomannan receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_59524)</deletedAxiom>
<newAxiom>&apos;lipoarabinomannan receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_59524)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001874</classIRI>
<classLabel>(1-3)-beta-D-glucan receptor activity</classLabel>
<deletedAxiom>&apos;(1-3)-beta-D-glucan receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_37671)</deletedAxiom>
<newAxiom>&apos;(1-3)-beta-D-glucan receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_37671)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001875</classIRI>
<classLabel>lipopolysaccharide receptor activity</classLabel>
<deletedAxiom>&apos;lipopolysaccharide receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_16412)</deletedAxiom>
<newAxiom>&apos;lipopolysaccharide receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_16412)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001873</classIRI>
<classLabel>polysaccharide receptor activity</classLabel>
<deletedAxiom>&apos;polysaccharide receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18154)</deletedAxiom>
<newAxiom>&apos;polysaccharide receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18154)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098709</classIRI>
<classLabel>glutathione import across plasma membrane</classLabel>
<deletedAxiom>&apos;glutathione import across plasma membrane&apos; SubClassOf &apos;import across plasma membrane&apos;</deletedAxiom>
<newAxiom>&apos;glutathione import across plasma membrane&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140207</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060022</classIRI>
<classLabel>hard palate development</classLabel>
<deletedAxiom>&apos;hard palate development&apos; SubClassOf &apos;part of&apos; some &apos;palate development&apos;</deletedAxiom>
<newAxiom>&apos;hard palate development&apos; SubClassOf &apos;part of&apos; some http://purl.obolibrary.org/obo/GO_0062009</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060023</classIRI>
<classLabel>soft palate development</classLabel>
<deletedAxiom>&apos;soft palate development&apos; SubClassOf &apos;part of&apos; some &apos;palate development&apos;</deletedAxiom>
<newAxiom>&apos;soft palate development&apos; SubClassOf &apos;part of&apos; some http://purl.obolibrary.org/obo/GO_0062009</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060089</classIRI>
<classLabel>molecular transducer activity</classLabel>
<deletedAxiom>&apos;molecular transducer activity&apos; SubClassOf &apos;molecular_function&apos;</deletedAxiom>
<deletedAxiom>&apos;molecular transducer activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;has regulatory component activity&apos; some &apos;molecular_function&apos;)</deletedAxiom>
<newAxiom>&apos;molecular transducer activity&apos; SubClassOf &apos;signal transducer activity&apos;</newAxiom>
<newAxiom>&apos;molecular transducer activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;part of&apos; some &apos;signal transduction&apos;) and (&apos;has regulatory component activity&apos; some &apos;molecular_function&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001785</classIRI>
<classLabel>prostaglandin J receptor activity</classLabel>
<deletedAxiom>&apos;prostaglandin J receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_26346)</deletedAxiom>
<newAxiom>&apos;prostaglandin J receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_26346)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001601</classIRI>
<classLabel>peptide YY receptor activity</classLabel>
<deletedAxiom>&apos;peptide YY receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000013526)</deletedAxiom>
<newAxiom>&apos;peptide YY receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000013526)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001602</classIRI>
<classLabel>pancreatic polypeptide receptor activity</classLabel>
<deletedAxiom>&apos;pancreatic polypeptide receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000013164)</deletedAxiom>
<newAxiom>&apos;pancreatic polypeptide receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000013164)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905201</classIRI>
<classLabel>gibberellin transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;gibberellin transmembrane transporter activity&apos; EquivalentTo &apos;transmembrane transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_24250)</deletedAxiom>
<newAxiom>&apos;gibberellin transmembrane transporter activity&apos; EquivalentTo &apos;transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_24250) and (&apos;results in transport across&apos; some &apos;membrane&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001653</classIRI>
<classLabel>peptide receptor activity</classLabel>
<deletedAxiom>&apos;peptide receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_16670)</deletedAxiom>
<newAxiom>&apos;peptide receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_16670)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001634</classIRI>
<classLabel>pituitary adenylate cyclase-activating polypeptide receptor activity</classLabel>
<deletedAxiom>&apos;pituitary adenylate cyclase-activating polypeptide receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000003761)</deletedAxiom>
<newAxiom>&apos;pituitary adenylate cyclase-activating polypeptide receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000003761)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001632</classIRI>
<classLabel>leukotriene B4 receptor activity</classLabel>
<deletedAxiom>&apos;leukotriene B4 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15647)</deletedAxiom>
<newAxiom>&apos;leukotriene B4 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15647)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001621</classIRI>
<classLabel>ADP receptor activity</classLabel>
<deletedAxiom>&apos;ADP receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_16761)</deletedAxiom>
<newAxiom>&apos;ADP receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_16761)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001616</classIRI>
<classLabel>growth hormone secretagogue receptor activity</classLabel>
<deletedAxiom>&apos;growth hormone secretagogue receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000007973)</deletedAxiom>
<newAxiom>&apos;growth hormone secretagogue receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000007973)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001595</classIRI>
<classLabel>angiotensin receptor activity</classLabel>
<deletedAxiom>&apos;angiotensin receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_48433)</deletedAxiom>
<newAxiom>&apos;angiotensin receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_48433)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001565</classIRI>
<classLabel>phorbol ester receptor activity</classLabel>
<deletedAxiom>&apos;phorbol ester receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_37532)</deletedAxiom>
<newAxiom>&apos;phorbol ester receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_37532)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001532</classIRI>
<classLabel>interleukin-21 receptor activity</classLabel>
<deletedAxiom>&apos;interleukin-21 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001382)</deletedAxiom>
<newAxiom>&apos;interleukin-21 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001382)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905599</classIRI>
<classLabel>positive regulation of low-density lipoprotein receptor activity</classLabel>
<deletedAxiom>&apos;positive regulation of low-density lipoprotein receptor activity&apos; SubClassOf &apos;positive regulation of receptor activity&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of low-density lipoprotein receptor activity&apos; SubClassOf &apos;positive regulation of molecular function&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905598</classIRI>
<classLabel>negative regulation of low-density lipoprotein receptor activity</classLabel>
<deletedAxiom>&apos;negative regulation of low-density lipoprotein receptor activity&apos; SubClassOf &apos;negative regulation of receptor activity&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of low-density lipoprotein receptor activity&apos; SubClassOf &apos;negative regulation of molecular function&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015794</classIRI>
<classLabel>glycerol-3-phosphate transport</classLabel>
<deletedAxiom>&apos;glycerol-3-phosphate transport&apos; EquivalentTo &apos;transport&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_15978)</deletedAxiom>
<newAxiom>&apos;glycerol-3-phosphate transport&apos; EquivalentTo &apos;transport&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_15978) and (&apos;results in transport across&apos; some &apos;membrane&apos;)</newAxiom>
<newAxiom>&apos;glycerol-3-phosphate transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015636</classIRI>
<classLabel>short-chain fatty acid transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;short-chain fatty acid transmembrane transporter activity&apos; EquivalentTo &apos;transmembrane transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_26666)</deletedAxiom>
<deletedAxiom>&apos;short-chain fatty acid transmembrane transporter activity&apos; SubClassOf &apos;monocarboxylic acid transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;short-chain fatty acid transmembrane transporter activity&apos; EquivalentTo &apos;transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_26666) and (&apos;results in transport across&apos; some &apos;membrane&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015638</classIRI>
<classLabel>microcin transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;microcin transmembrane transporter activity&apos; EquivalentTo &apos;transmembrane transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_64627)</deletedAxiom>
<newAxiom>&apos;microcin transmembrane transporter activity&apos; EquivalentTo &apos;transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_64627) and (&apos;results in transport across&apos; some &apos;membrane&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015645</classIRI>
<classLabel>fatty acid ligase activity</classLabel>
<deletedAxiom>&apos;fatty acid ligase activity&apos; SubClassOf &apos;ligase activity, forming carbon-sulfur bonds&apos;</deletedAxiom>
<newAxiom>&apos;fatty acid ligase activity&apos; SubClassOf &apos;acid-thiol ligase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904604</classIRI>
<classLabel>negative regulation of advanced glycation end-product receptor activity</classLabel>
<deletedAxiom>&apos;negative regulation of advanced glycation end-product receptor activity&apos; SubClassOf &apos;negative regulation of signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904605</classIRI>
<classLabel>positive regulation of advanced glycation end-product receptor activity</classLabel>
<deletedAxiom>&apos;positive regulation of advanced glycation end-product receptor activity&apos; SubClassOf &apos;positive regulation of signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904543</classIRI>
<classLabel>negative regulation of free ubiquitin chain polymerization</classLabel>
<deletedAxiom>&apos;negative regulation of free ubiquitin chain polymerization&apos; SubClassOf &apos;negative regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904544</classIRI>
<classLabel>positive regulation of free ubiquitin chain polymerization</classLabel>
<deletedAxiom>&apos;positive regulation of free ubiquitin chain polymerization&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904542</classIRI>
<classLabel>regulation of free ubiquitin chain polymerization</classLabel>
<deletedAxiom>&apos;regulation of free ubiquitin chain polymerization&apos; SubClassOf &apos;regulation of homeostatic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of free ubiquitin chain polymerization&apos; SubClassOf &apos;regulation of biological quality&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015552</classIRI>
<classLabel>propionate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;propionate transmembrane transporter activity&apos; EquivalentTo &apos;transmembrane transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_17272)</deletedAxiom>
<newAxiom>&apos;propionate transmembrane transporter activity&apos; EquivalentTo &apos;transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_17272) and (&apos;results in transport across&apos; some &apos;membrane&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015464</classIRI>
<classLabel>acetylcholine receptor activity</classLabel>
<deletedAxiom>&apos;acetylcholine receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15355)</deletedAxiom>
<newAxiom>&apos;acetylcholine receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15355)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015483</classIRI>
<classLabel>long-chain fatty acid transporting porin activity</classLabel>
<deletedAxiom>&apos;long-chain fatty acid transporting porin activity&apos; SubClassOf &apos;monocarboxylic acid transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;long-chain fatty acid transporting porin activity&apos; SubClassOf &apos;fatty acid transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904680</classIRI>
<classLabel>peptide transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;peptide transmembrane transporter activity&apos; SubClassOf &apos;peptide transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide transmembrane transporter activity&apos; EquivalentTo &apos;transmembrane transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_16670)</deletedAxiom>
<newAxiom>&apos;peptide transmembrane transporter activity&apos; SubClassOf &apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_16670</newAxiom>
<newAxiom>&apos;peptide transmembrane transporter activity&apos; EquivalentTo &apos;transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_16670) and (&apos;results in transport across&apos; some &apos;membrane&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015245</classIRI>
<classLabel>fatty acid transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;fatty acid transmembrane transporter activity&apos; EquivalentTo &apos;transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_35366)</deletedAxiom>
<newAxiom>&apos;fatty acid transmembrane transporter activity&apos; SubClassOf &apos;monocarboxylic acid transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;fatty acid transmembrane transporter activity&apos; EquivalentTo &apos;transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_35366) and (&apos;results in transport across&apos; some &apos;membrane&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030811</classIRI>
<classLabel>regulation of nucleotide catabolic process</classLabel>
<newAxiom>&apos;regulation of nucleotide catabolic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030812</classIRI>
<classLabel>negative regulation of nucleotide catabolic process</classLabel>
<newAxiom>&apos;negative regulation of nucleotide catabolic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030813</classIRI>
<classLabel>positive regulation of nucleotide catabolic process</classLabel>
<newAxiom>&apos;positive regulation of nucleotide catabolic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015204</classIRI>
<classLabel>urea transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;urea transmembrane transporter activity&apos; EquivalentTo &apos;transmembrane transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_16199)</deletedAxiom>
<newAxiom>&apos;urea transmembrane transporter activity&apos; EquivalentTo &apos;transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_16199) and (&apos;results in transport across&apos; some &apos;membrane&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015132</classIRI>
<classLabel>prostaglandin transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;prostaglandin transmembrane transporter activity&apos; EquivalentTo &apos;transmembrane transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_26333)</deletedAxiom>
<deletedAxiom>&apos;prostaglandin transmembrane transporter activity&apos; SubClassOf &apos;monocarboxylic acid transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;prostaglandin transmembrane transporter activity&apos; EquivalentTo &apos;transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_26333) and (&apos;results in transport across&apos; some &apos;membrane&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015197</classIRI>
<classLabel>peptide transporter activity</classLabel>
<deletedAxiom>&apos;peptide transporter activity&apos; SubClassOf &apos;transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide transporter activity&apos; SubClassOf &apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_16670</deletedAxiom>
<deletedAxiom>&apos;peptide transporter activity&apos; EquivalentTo &apos;transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_16670)</deletedAxiom>
<deletedAxiom>&apos;peptide transporter activity&apos; SubClassOf &apos;part of&apos; some &apos;peptide transport&apos;</deletedAxiom>
<newAxiom>&apos;peptide transporter activity&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015055</classIRI>
<classLabel>secretin receptor activity</classLabel>
<deletedAxiom>&apos;secretin receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000014543)</deletedAxiom>
<newAxiom>&apos;secretin receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000014543)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015054</classIRI>
<classLabel>gastrin receptor activity</classLabel>
<deletedAxiom>&apos;gastrin receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000007856)</deletedAxiom>
<newAxiom>&apos;gastrin receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000007856)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900011</classIRI>
<classLabel>negative regulation of corticotropin-releasing hormone receptor activity</classLabel>
<deletedAxiom>&apos;negative regulation of corticotropin-releasing hormone receptor activity&apos; SubClassOf &apos;negative regulation of signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900012</classIRI>
<classLabel>positive regulation of corticotropin-releasing hormone receptor activity</classLabel>
<deletedAxiom>&apos;positive regulation of corticotropin-releasing hormone receptor activity&apos; SubClassOf &apos;positive regulation of signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030545</classIRI>
<classLabel>receptor regulator activity</classLabel>
<deletedAxiom>&apos;receptor regulator activity&apos; SubClassOf &apos;directly regulates&apos; some &apos;receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;receptor regulator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly regulates&apos; some &apos;receptor activity&apos;)</deletedAxiom>
<newAxiom>&apos;receptor regulator activity&apos; SubClassOf &apos;directly regulates&apos; some &apos;signaling receptor activity&apos;</newAxiom>
<newAxiom>&apos;receptor regulator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly regulates&apos; some &apos;signaling receptor activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030546</classIRI>
<classLabel>receptor activator activity</classLabel>
<deletedAxiom>&apos;receptor activator activity&apos; SubClassOf &apos;directly positively regulates&apos; some &apos;receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;receptor activator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly positively regulates&apos; some &apos;receptor activity&apos;)</deletedAxiom>
<newAxiom>&apos;receptor activator activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly positively regulates&apos; some &apos;signaling receptor activity&apos;)</newAxiom>
<newAxiom>&apos;receptor activator activity&apos; SubClassOf &apos;directly positively regulates&apos; some &apos;signaling receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030547</classIRI>
<classLabel>receptor inhibitor activity</classLabel>
<deletedAxiom>&apos;receptor inhibitor activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly negatively regulates&apos; some &apos;receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;receptor inhibitor activity&apos; SubClassOf &apos;directly negatively regulates&apos; some &apos;receptor activity&apos;</deletedAxiom>
<newAxiom>&apos;receptor inhibitor activity&apos; EquivalentTo &apos;molecular_function&apos; and (&apos;directly negatively regulates&apos; some &apos;signaling receptor activity&apos;)</newAxiom>
<newAxiom>&apos;receptor inhibitor activity&apos; SubClassOf &apos;directly negatively regulates&apos; some &apos;signaling receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005324</classIRI>
<classLabel>long-chain fatty acid transporter activity</classLabel>
<deletedAxiom>&apos;long-chain fatty acid transporter activity&apos; SubClassOf &apos;fatty acid transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;long-chain fatty acid transporter activity&apos; SubClassOf &apos;lipid transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030377</classIRI>
<classLabel>urokinase plasminogen activator receptor activity</classLabel>
<deletedAxiom>&apos;urokinase plasminogen activator receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000012826)</deletedAxiom>
<newAxiom>&apos;urokinase plasminogen activator receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000012826)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030368</classIRI>
<classLabel>interleukin-17 receptor activity</classLabel>
<deletedAxiom>&apos;interleukin-17 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001092)</deletedAxiom>
<newAxiom>&apos;interleukin-17 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001092)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030369</classIRI>
<classLabel>ICAM-3 receptor activity</classLabel>
<deletedAxiom>&apos;ICAM-3 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001468)</deletedAxiom>
<newAxiom>&apos;ICAM-3 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001468)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030226</classIRI>
<classLabel>apolipoprotein receptor activity</classLabel>
<deletedAxiom>&apos;apolipoprotein receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_39015)</deletedAxiom>
<deletedAxiom>&apos;apolipoprotein receptor activity&apos; SubClassOf &apos;receptor activity&apos;</deletedAxiom>
<newAxiom>&apos;apolipoprotein receptor activity&apos; EquivalentTo &apos;cargo receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_39015)</newAxiom>
<newAxiom>&apos;apolipoprotein receptor activity&apos; SubClassOf &apos;cargo receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030228</classIRI>
<classLabel>lipoprotein particle receptor activity</classLabel>
<deletedAxiom>&apos;lipoprotein particle receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_6495)</deletedAxiom>
<newAxiom>&apos;lipoprotein particle receptor activity&apos; EquivalentTo &apos;cargo receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_6495)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030229</classIRI>
<classLabel>very-low-density lipoprotein particle receptor activity</classLabel>
<newAxiom>&apos;very-low-density lipoprotein particle receptor activity&apos; EquivalentTo &apos;cargo receptor activity&apos; and (&apos;has input&apos; some &apos;very-low-density lipoprotein particle&apos;)</newAxiom>
<newAxiom>&apos;very-low-density lipoprotein particle receptor activity&apos; SubClassOf &apos;has input&apos; some &apos;very-low-density lipoprotein particle&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030284</classIRI>
<classLabel>estrogen receptor activity</classLabel>
<deletedAxiom>&apos;estrogen receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_50114)</deletedAxiom>
<newAxiom>&apos;estrogen receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_50114)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005000</classIRI>
<classLabel>vasopressin receptor activity</classLabel>
<deletedAxiom>&apos;vasopressin receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_9937)</deletedAxiom>
<newAxiom>&apos;vasopressin receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_9937)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005006</classIRI>
<classLabel>epidermal growth factor-activated receptor activity</classLabel>
<deletedAxiom>&apos;epidermal growth factor-activated receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000006928)</deletedAxiom>
<newAxiom>&apos;epidermal growth factor-activated receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000006928)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005008</classIRI>
<classLabel>hepatocyte growth factor-activated receptor activity</classLabel>
<deletedAxiom>&apos;hepatocyte growth factor-activated receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000008534)</deletedAxiom>
<newAxiom>&apos;hepatocyte growth factor-activated receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000008534)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005009</classIRI>
<classLabel>insulin-activated receptor activity</classLabel>
<deletedAxiom>&apos;insulin-activated receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000009054)</deletedAxiom>
<newAxiom>&apos;insulin-activated receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000009054)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019653</classIRI>
<classLabel>anaerobic purine nucleobase catabolic process</classLabel>
<newAxiom>&apos;anaerobic purine nucleobase catabolic process&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_35584</newAxiom>
<newAxiom>&apos;anaerobic purine nucleobase catabolic process&apos; EquivalentTo &apos;fermentation&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_35584)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019657</classIRI>
<classLabel>glycolytic fermentation to propionate</classLabel>
<deletedAxiom>&apos;glycolytic fermentation to propionate&apos; SubClassOf &apos;propionate metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;glycolytic fermentation to propionate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17272</deletedAxiom>
<newAxiom>&apos;glycolytic fermentation to propionate&apos; SubClassOf &apos;nucleotide catabolic process&apos;</newAxiom>
<newAxiom>&apos;glycolytic fermentation to propionate&apos; SubClassOf &apos;propionate biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019660</classIRI>
<classLabel>glycolytic fermentation</classLabel>
<deletedAxiom>&apos;glycolytic fermentation&apos; SubClassOf &apos;fermentation&apos;</deletedAxiom>
<newAxiom>&apos;glycolytic fermentation&apos; SubClassOf &apos;nitrogenous compound fermentation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019661</classIRI>
<classLabel>glucose catabolic process to lactate via pyruvate</classLabel>
<newAxiom>&apos;glucose catabolic process to lactate via pyruvate&apos; SubClassOf &apos;lactate biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;glucose catabolic process to lactate via pyruvate&apos; SubClassOf &apos;nucleotide catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019665</classIRI>
<classLabel>anaerobic amino acid catabolic process</classLabel>
<deletedAxiom>&apos;anaerobic amino acid catabolic process&apos; SubClassOf &apos;fermentation&apos;</deletedAxiom>
<newAxiom>&apos;anaerobic amino acid catabolic process&apos; SubClassOf &apos;nitrogenous compound fermentation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019666</classIRI>
<classLabel>nitrogenous compound fermentation</classLabel>
<newAxiom>&apos;nitrogenous compound fermentation&apos; EquivalentTo &apos;fermentation&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_51143)</newAxiom>
<newAxiom>&apos;nitrogenous compound fermentation&apos; SubClassOf &apos;nitrogen compound metabolic process&apos;</newAxiom>
<newAxiom>&apos;nitrogenous compound fermentation&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_51143</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019667</classIRI>
<classLabel>anaerobic L-alanine catabolic process</classLabel>
<newAxiom>&apos;anaerobic L-alanine catabolic process&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_16977</newAxiom>
<newAxiom>&apos;anaerobic L-alanine catabolic process&apos; EquivalentTo &apos;anaerobic amino acid catabolic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_16977)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019669</classIRI>
<classLabel>anaerobic glycine catabolic process</classLabel>
<newAxiom>&apos;anaerobic glycine catabolic process&apos; EquivalentTo &apos;anaerobic amino acid catabolic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15428)</newAxiom>
<newAxiom>&apos;anaerobic glycine catabolic process&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15428</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005020</classIRI>
<classLabel>stem cell factor receptor activity</classLabel>
<deletedAxiom>&apos;stem cell factor receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000009345)</deletedAxiom>
<newAxiom>&apos;stem cell factor receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000009345)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005024</classIRI>
<classLabel>transforming growth factor beta-activated receptor activity</classLabel>
<deletedAxiom>&apos;transforming growth factor beta-activated receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000000046)</deletedAxiom>
<newAxiom>&apos;transforming growth factor beta-activated receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000000046)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019670</classIRI>
<classLabel>anaerobic glutamate catabolic process</classLabel>
<newAxiom>&apos;anaerobic glutamate catabolic process&apos; EquivalentTo &apos;anaerobic amino acid catabolic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18237)</newAxiom>
<newAxiom>&apos;anaerobic glutamate catabolic process&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18237</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005041</classIRI>
<classLabel>low-density lipoprotein particle receptor activity</classLabel>
<deletedAxiom>&apos;low-density lipoprotein particle receptor activity&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_39026</deletedAxiom>
<deletedAxiom>&apos;low-density lipoprotein particle receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_39026)</deletedAxiom>
<newAxiom>&apos;low-density lipoprotein particle receptor activity&apos; EquivalentTo &apos;cargo receptor activity&apos; and (&apos;has input&apos; some &apos;low-density lipoprotein particle&apos;)</newAxiom>
<newAxiom>&apos;low-density lipoprotein particle receptor activity&apos; SubClassOf &apos;has input&apos; some &apos;low-density lipoprotein particle&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005055</classIRI>
<classLabel>laminin receptor activity</classLabel>
<deletedAxiom>&apos;laminin receptor activity&apos; SubClassOf &apos;receptor activity&apos;</deletedAxiom>
<newAxiom>&apos;laminin receptor activity&apos; SubClassOf &apos;cell adhesion mediator activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019451</classIRI>
<classLabel>L-cysteine catabolic process to pyruvate, using cysteine dioxygenase</classLabel>
<newAxiom>&apos;L-cysteine catabolic process to pyruvate, using cysteine dioxygenase&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has participant&apos; some &apos;cysteine dioxygenase activity&apos;) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32442) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15361)</newAxiom>
<newAxiom>&apos;L-cysteine catabolic process to pyruvate, using cysteine dioxygenase&apos; SubClassOf &apos;has participant&apos; some &apos;cysteine dioxygenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019453</classIRI>
<classLabel>L-cysteine catabolic process via cystine</classLabel>
<newAxiom>&apos;L-cysteine catabolic process via cystine&apos; SubClassOf &apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_17376</newAxiom>
<newAxiom>&apos;L-cysteine catabolic process via cystine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17561</newAxiom>
<newAxiom>&apos;L-cysteine catabolic process via cystine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_17376) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17561)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019454</classIRI>
<classLabel>L-cysteine catabolic process via cystine, using glutathione-cystine transhydrogenase</classLabel>
<newAxiom>&apos;L-cysteine catabolic process via cystine, using glutathione-cystine transhydrogenase&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_17376) and (&apos;has participant&apos; some &apos;glutathione-cystine transhydrogenase activity&apos;) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17561)</newAxiom>
<newAxiom>&apos;L-cysteine catabolic process via cystine, using glutathione-cystine transhydrogenase&apos; SubClassOf &apos;has participant&apos; some &apos;glutathione-cystine transhydrogenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019455</classIRI>
<classLabel>L-cysteine catabolic process via cystine, using cystine reductase</classLabel>
<newAxiom>&apos;L-cysteine catabolic process via cystine, using cystine reductase&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_17376) and (&apos;has participant&apos; some &apos;cystine reductase activity&apos;) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17561)</newAxiom>
<newAxiom>&apos;L-cysteine catabolic process via cystine, using cystine reductase&apos; SubClassOf &apos;has participant&apos; some &apos;cystine reductase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019461</classIRI>
<classLabel>glutamine catabolic process to fumarate, using glutamate synthase (NADPH)</classLabel>
<deletedAxiom>&apos;glutamine catabolic process to fumarate, using glutamate synthase (NADPH)&apos; SubClassOf &apos;has_part&apos; some &apos;glutamate synthase (NADPH) activity&apos;</deletedAxiom>
<newAxiom>&apos;glutamine catabolic process to fumarate, using glutamate synthase (NADPH)&apos; SubClassOf &apos;has participant&apos; some &apos;glutamate synthase (NADPH) activity&apos;</newAxiom>
<newAxiom>&apos;glutamine catabolic process to fumarate, using glutamate synthase (NADPH)&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has participant&apos; some &apos;glutamate synthase (NADPH) activity&apos;) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_29806)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019462</classIRI>
<classLabel>glutamine catabolic process to fumarate, using glutaminase</classLabel>
<deletedAxiom>&apos;glutamine catabolic process to fumarate, using glutaminase&apos; SubClassOf &apos;has_part&apos; some &apos;glutaminase activity&apos;</deletedAxiom>
<newAxiom>&apos;glutamine catabolic process to fumarate, using glutaminase&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has participant&apos; some &apos;glutaminase activity&apos;) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_29806)</newAxiom>
<newAxiom>&apos;glutamine catabolic process to fumarate, using glutaminase&apos; SubClassOf &apos;has participant&apos; some &apos;glutaminase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019467</classIRI>
<classLabel>ornithine catabolic process, by decarboxylation</classLabel>
<newAxiom>&apos;ornithine catabolic process, by decarboxylation&apos; SubClassOf &apos;has participant&apos; some &apos;carboxy-lyase activity&apos;</newAxiom>
<newAxiom>&apos;ornithine catabolic process, by decarboxylation&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has participant&apos; some &apos;carboxy-lyase activity&apos;) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32964)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019346</classIRI>
<classLabel>transsulfuration</classLabel>
<newAxiom>&apos;transsulfuration&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17230</newAxiom>
<newAxiom>&apos;transsulfuration&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15356</newAxiom>
<newAxiom>&apos;transsulfuration&apos; SubClassOf &apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_17755</newAxiom>
<newAxiom>&apos;transsulfuration&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_17755) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17230) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15356)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007253</classIRI>
<classLabel>cytoplasmic sequestering of NF-kappaB</classLabel>
<deletedAxiom>&apos;cytoplasmic sequestering of NF-kappaB&apos; SubClassOf &apos;negative regulation of NF-kappaB import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;cytoplasmic sequestering of NF-kappaB&apos; SubClassOf &apos;part of&apos; some &apos;negative regulation of I-kappaB kinase/NF-kappaB signaling&apos;</deletedAxiom>
<newAxiom>&apos;cytoplasmic sequestering of NF-kappaB&apos; SubClassOf &apos;negative regulation of NF-kappaB transcription factor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007262</classIRI>
<classLabel>STAT protein import into nucleus</classLabel>
<deletedAxiom>&apos;STAT protein import into nucleus&apos; SubClassOf &apos;protein import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;STAT protein import into nucleus&apos; SubClassOf &apos;part of&apos; some &apos;JAK-STAT cascade&apos;</deletedAxiom>
<newAxiom>&apos;STAT protein import into nucleus&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032204</classIRI>
<classLabel>regulation of telomere maintenance</classLabel>
<deletedAxiom>&apos;regulation of telomere maintenance&apos; SubClassOf &apos;regulation of homeostatic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of telomere maintenance&apos; SubClassOf &apos;regulation of biological quality&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032206</classIRI>
<classLabel>positive regulation of telomere maintenance</classLabel>
<deletedAxiom>&apos;positive regulation of telomere maintenance&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032205</classIRI>
<classLabel>negative regulation of telomere maintenance</classLabel>
<deletedAxiom>&apos;negative regulation of telomere maintenance&apos; SubClassOf &apos;negative regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007131</classIRI>
<classLabel>reciprocal meiotic recombination</classLabel>
<deletedAxiom>&apos;reciprocal meiotic recombination&apos; SubClassOf &apos;meiosis I cell cycle process&apos;</deletedAxiom>
<newAxiom>&apos;reciprocal meiotic recombination&apos; SubClassOf &apos;part of&apos; some &apos;meiosis I&apos;</newAxiom>
<newAxiom>&apos;reciprocal meiotic recombination&apos; SubClassOf &apos;meiotic cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061722</classIRI>
<classLabel>sulphoglycolysis</classLabel>
<deletedAxiom>&apos;sulphoglycolysis&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15361</deletedAxiom>
<deletedAxiom>&apos;sulphoglycolysis&apos; SubClassOf &apos;pyruvate metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;sulphoglycolysis&apos; SubClassOf &apos;nucleotide catabolic process&apos;</newAxiom>
<newAxiom>&apos;sulphoglycolysis&apos; SubClassOf &apos;NAD biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;sulphoglycolysis&apos; SubClassOf &apos;pyruvate biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;sulphoglycolysis&apos; SubClassOf &apos;ATP biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061773</classIRI>
<classLabel>eNoSc complex</classLabel>
<deletedAxiom>&apos;eNoSc complex&apos; SubClassOf &apos;capable of part of&apos; some &apos;regulation of energy homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;eNoSc complex&apos; SubClassOf &apos;capable of part of&apos; some &apos;energy homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046014</classIRI>
<classLabel>negative regulation of T cell homeostatic proliferation</classLabel>
<deletedAxiom>&apos;negative regulation of T cell homeostatic proliferation&apos; SubClassOf &apos;negative regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046013</classIRI>
<classLabel>regulation of T cell homeostatic proliferation</classLabel>
<deletedAxiom>&apos;regulation of T cell homeostatic proliferation&apos; SubClassOf &apos;regulation of homeostatic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of T cell homeostatic proliferation&apos; SubClassOf &apos;regulation of biological quality&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061621</classIRI>
<classLabel>canonical glycolysis</classLabel>
<newAxiom>&apos;canonical glycolysis&apos; SubClassOf &apos;NAD biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002907</classIRI>
<classLabel>positive regulation of mature B cell apoptotic process</classLabel>
<deletedAxiom>&apos;positive regulation of mature B cell apoptotic process&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002906</classIRI>
<classLabel>negative regulation of mature B cell apoptotic process</classLabel>
<deletedAxiom>&apos;negative regulation of mature B cell apoptotic process&apos; SubClassOf &apos;negative regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002905</classIRI>
<classLabel>regulation of mature B cell apoptotic process</classLabel>
<deletedAxiom>&apos;regulation of mature B cell apoptotic process&apos; SubClassOf &apos;regulation of homeostatic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of mature B cell apoptotic process&apos; SubClassOf &apos;regulation of biological quality&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036319</classIRI>
<classLabel>mating-type M-factor pheromone receptor activity</classLabel>
<deletedAxiom>&apos;mating-type M-factor pheromone receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_64120)</deletedAxiom>
<newAxiom>&apos;mating-type M-factor pheromone receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_64120)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036318</classIRI>
<classLabel>peptide pheromone receptor activity</classLabel>
<deletedAxiom>&apos;peptide pheromone receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_38579)</deletedAxiom>
<newAxiom>&apos;peptide pheromone receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_38579)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036320</classIRI>
<classLabel>mating-type P-factor pheromone receptor activity</classLabel>
<deletedAxiom>&apos;mating-type P-factor pheromone receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_64121)</deletedAxiom>
<newAxiom>&apos;mating-type P-factor pheromone receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_64121)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036283</classIRI>
<classLabel>positive regulation of transcription factor import into nucleus in response to oxidative stress</classLabel>
<deletedAxiom>&apos;positive regulation of transcription factor import into nucleus in response to oxidative stress&apos; SubClassOf &apos;part of&apos; some &apos;cellular response to oxidative stress&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription factor import into nucleus in response to oxidative stress&apos; SubClassOf &apos;positive regulation of transcription factor import into nucleus&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of transcription factor import into nucleus in response to oxidative stress&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061179</classIRI>
<classLabel>negative regulation of insulin secretion involved in cellular response to glucose stimulus</classLabel>
<deletedAxiom>&apos;negative regulation of insulin secretion involved in cellular response to glucose stimulus&apos; SubClassOf &apos;negative regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061178</classIRI>
<classLabel>regulation of insulin secretion involved in cellular response to glucose stimulus</classLabel>
<deletedAxiom>&apos;regulation of insulin secretion involved in cellular response to glucose stimulus&apos; SubClassOf &apos;regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904023</classIRI>
<classLabel>regulation of glucose catabolic process to lactate via pyruvate</classLabel>
<newAxiom>&apos;regulation of glucose catabolic process to lactate via pyruvate&apos; SubClassOf &apos;regulation of nucleotide catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904025</classIRI>
<classLabel>positive regulation of glucose catabolic process to lactate via pyruvate</classLabel>
<deletedAxiom>&apos;positive regulation of glucose catabolic process to lactate via pyruvate&apos; SubClassOf &apos;positive regulation of catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of glucose catabolic process to lactate via pyruvate&apos; SubClassOf &apos;positive regulation of nucleotide catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904024</classIRI>
<classLabel>negative regulation of glucose catabolic process to lactate via pyruvate</classLabel>
<deletedAxiom>&apos;negative regulation of glucose catabolic process to lactate via pyruvate&apos; SubClassOf &apos;negative regulation of catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of glucose catabolic process to lactate via pyruvate&apos; SubClassOf &apos;negative regulation of nucleotide catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099600</classIRI>
<classLabel>transmembrane receptor activity</classLabel>
<deletedAxiom>&apos;transmembrane receptor activity&apos; SubClassOf &apos;receptor activity&apos;</deletedAxiom>
<newAxiom>&apos;transmembrane receptor activity&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061088</classIRI>
<classLabel>regulation of sequestering of zinc ion</classLabel>
<deletedAxiom>&apos;regulation of sequestering of zinc ion&apos; SubClassOf &apos;regulation of ion homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;regulation of sequestering of zinc ion&apos; SubClassOf &apos;ion homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061090</classIRI>
<classLabel>positive regulation of sequestering of zinc ion</classLabel>
<deletedAxiom>&apos;positive regulation of sequestering of zinc ion&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061089</classIRI>
<classLabel>negative regulation of sequestering of zinc ion</classLabel>
<deletedAxiom>&apos;negative regulation of sequestering of zinc ion&apos; SubClassOf &apos;negative regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904168</classIRI>
<classLabel>negative regulation of thyroid hormone receptor activity</classLabel>
<deletedAxiom>&apos;negative regulation of thyroid hormone receptor activity&apos; SubClassOf &apos;negative regulation of signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904169</classIRI>
<classLabel>positive regulation of thyroid hormone receptor activity</classLabel>
<deletedAxiom>&apos;positive regulation of thyroid hormone receptor activity&apos; SubClassOf &apos;positive regulation of signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051534</classIRI>
<classLabel>negative regulation of NFAT protein import into nucleus</classLabel>
<deletedAxiom>&apos;negative regulation of NFAT protein import into nucleus&apos; SubClassOf &apos;regulation of NFAT protein import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of NFAT protein import into nucleus&apos; SubClassOf &apos;negatively regulates&apos; some &apos;NFAT protein import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of NFAT protein import into nucleus&apos; SubClassOf &apos;negative regulation of transcription factor import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of NFAT protein import into nucleus&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;NFAT protein import into nucleus&apos;)</deletedAxiom>
<newAxiom>&apos;negative regulation of NFAT protein import into nucleus&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051531</classIRI>
<classLabel>NFAT protein import into nucleus</classLabel>
<deletedAxiom>&apos;NFAT protein import into nucleus&apos; EquivalentTo &apos;nuclear import&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/PR_000003112)</deletedAxiom>
<deletedAxiom>&apos;NFAT protein import into nucleus&apos; SubClassOf &apos;transcription factor import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;NFAT protein import into nucleus&apos; SubClassOf &apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/PR_000003112</deletedAxiom>
<newAxiom>&apos;NFAT protein import into nucleus&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051533</classIRI>
<classLabel>positive regulation of NFAT protein import into nucleus</classLabel>
<deletedAxiom>&apos;positive regulation of NFAT protein import into nucleus&apos; SubClassOf &apos;positively regulates&apos; some &apos;NFAT protein import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of NFAT protein import into nucleus&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;NFAT protein import into nucleus&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of NFAT protein import into nucleus&apos; SubClassOf &apos;positive regulation of transcription factor import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of NFAT protein import into nucleus&apos; SubClassOf &apos;regulation of NFAT protein import into nucleus&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of NFAT protein import into nucleus&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051532</classIRI>
<classLabel>regulation of NFAT protein import into nucleus</classLabel>
<deletedAxiom>&apos;regulation of NFAT protein import into nucleus&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;NFAT protein import into nucleus&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of NFAT protein import into nucleus&apos; SubClassOf &apos;regulation of transcription factor import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of NFAT protein import into nucleus&apos; SubClassOf &apos;regulates&apos; some &apos;NFAT protein import into nucleus&apos;</deletedAxiom>
<newAxiom>&apos;regulation of NFAT protein import into nucleus&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904296</classIRI>
<classLabel>negative regulation of osmolarity-sensing cation channel activity</classLabel>
<deletedAxiom>&apos;negative regulation of osmolarity-sensing cation channel activity&apos; SubClassOf &apos;negative regulation of signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904297</classIRI>
<classLabel>positive regulation of osmolarity-sensing cation channel activity</classLabel>
<deletedAxiom>&apos;positive regulation of osmolarity-sensing cation channel activity&apos; SubClassOf &apos;positive regulation of signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051436</classIRI>
<classLabel>negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle</classLabel>
<deletedAxiom>&apos;negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle&apos; SubClassOf &apos;regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle&apos; EquivalentTo &apos;negative regulation of ubiquitin protein ligase activity&apos; and (&apos;part of&apos; some &apos;mitotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle&apos; SubClassOf &apos;negative regulation of ubiquitin protein ligase activity&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051437</classIRI>
<classLabel>positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition</classLabel>
<deletedAxiom>&apos;positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition&apos; SubClassOf &apos;positive regulation of ubiquitin-dependent protein catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition&apos; SubClassOf &apos;positive regulation of ubiquitin protein ligase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition&apos; SubClassOf &apos;part of&apos; some &apos;regulation of mitotic cell cycle phase transition&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition&apos; EquivalentTo &apos;positive regulation of ubiquitin protein ligase activity&apos; and (&apos;part of&apos; some &apos;regulation of mitotic cell cycle phase transition&apos;)</deletedAxiom>
<newAxiom>&apos;positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051439</classIRI>
<classLabel>regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle</classLabel>
<deletedAxiom>&apos;regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle&apos; EquivalentTo &apos;regulation of ubiquitin protein ligase activity&apos; and (&apos;part of&apos; some &apos;mitotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle&apos; SubClassOf &apos;regulation of ubiquitin protein ligase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle&apos; SubClassOf &apos;mitotic cell cycle process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051441</classIRI>
<classLabel>positive regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle</classLabel>
<deletedAxiom>&apos;positive regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle&apos; SubClassOf &apos;positive regulation of ubiquitin protein ligase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle&apos; SubClassOf &apos;regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle&apos; EquivalentTo &apos;positive regulation of ubiquitin-protein transferase activity&apos; and (&apos;part of&apos; some &apos;meiotic cell cycle&apos;)</deletedAxiom>
<newAxiom>&apos;positive regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051440</classIRI>
<classLabel>regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle</classLabel>
<deletedAxiom>&apos;regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle&apos; EquivalentTo &apos;regulation of ubiquitin protein ligase activity&apos; and (&apos;part of&apos; some &apos;meiotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle&apos; SubClassOf &apos;meiotic cell cycle process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle&apos; SubClassOf &apos;regulation of ubiquitin protein ligase activity&apos;</deletedAxiom>
<newAxiom>&apos;regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051442</classIRI>
<classLabel>negative regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle</classLabel>
<deletedAxiom>&apos;negative regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle&apos; EquivalentTo &apos;negative regulation of ubiquitin protein ligase activity&apos; and (&apos;part of&apos; some &apos;meiotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle&apos; SubClassOf &apos;negative regulation of ubiquitin protein ligase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle&apos; SubClassOf &apos;regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051395</classIRI>
<classLabel>negative regulation of nerve growth factor receptor activity</classLabel>
<deletedAxiom>&apos;negative regulation of nerve growth factor receptor activity&apos; SubClassOf &apos;negative regulation of signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051396</classIRI>
<classLabel>positive regulation of nerve growth factor receptor activity</classLabel>
<deletedAxiom>&apos;positive regulation of nerve growth factor receptor activity&apos; SubClassOf &apos;positive regulation of signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016917</classIRI>
<classLabel>GABA receptor activity</classLabel>
<deletedAxiom>&apos;GABA receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_30566)</deletedAxiom>
<newAxiom>&apos;GABA receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_30566)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075246</classIRI>
<classLabel>negative regulation of oospore formation</classLabel>
<deletedAxiom>&apos;negative regulation of oospore formation&apos; SubClassOf &apos;negative regulation of biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051284</classIRI>
<classLabel>positive regulation of sequestering of calcium ion</classLabel>
<deletedAxiom>&apos;positive regulation of sequestering of calcium ion&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051283</classIRI>
<classLabel>negative regulation of sequestering of calcium ion</classLabel>
<deletedAxiom>&apos;negative regulation of sequestering of calcium ion&apos; SubClassOf &apos;negative regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051282</classIRI>
<classLabel>regulation of sequestering of calcium ion</classLabel>
<deletedAxiom>&apos;regulation of sequestering of calcium ion&apos; SubClassOf &apos;regulation of ion homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;regulation of sequestering of calcium ion&apos; SubClassOf &apos;regulation of biological quality&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075245</classIRI>
<classLabel>positive regulation of oospore formation</classLabel>
<deletedAxiom>&apos;positive regulation of oospore formation&apos; SubClassOf &apos;positive regulation of biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075244</classIRI>
<classLabel>regulation of oospore formation</classLabel>
<deletedAxiom>&apos;regulation of oospore formation&apos; SubClassOf &apos;regulation of biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075243</classIRI>
<classLabel>oospore formation</classLabel>
<deletedAxiom>&apos;oospore formation&apos; SubClassOf &apos;biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;oospore formation&apos; EquivalentTo &apos;biosynthetic process&apos; and &apos;anatomical structure formation involved in morphogenesis&apos; and (&apos;results in formation of&apos; some http://purl.obolibrary.org/obo/CL_0002380) and (&apos;results in formation of&apos; some http://purl.obolibrary.org/obo/FAO_0000039)</deletedAxiom>
<deletedAxiom>&apos;oospore formation&apos; SubClassOf &apos;results in formation of&apos; some http://purl.obolibrary.org/obo/CL_0002380</deletedAxiom>
<newAxiom>&apos;oospore formation&apos; EquivalentTo &apos;anatomical structure formation involved in morphogenesis&apos; and (&apos;results in formation of&apos; some http://purl.obolibrary.org/obo/FAO_0000039)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002114</classIRI>
<classLabel>interleukin-33 receptor activity</classLabel>
<deletedAxiom>&apos;interleukin-33 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001389)</deletedAxiom>
<newAxiom>&apos;interleukin-33 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001389)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002005</classIRI>
<classLabel>angiotensin catabolic process in blood</classLabel>
<newAxiom>&apos;angiotensin catabolic process in blood&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;occurs in&apos; some http://purl.obolibrary.org/obo/UBERON_0000178) and (&apos;results in formation of&apos; some http://purl.obolibrary.org/obo/CHEBI_48433)</newAxiom>
<newAxiom>&apos;angiotensin catabolic process in blood&apos; SubClassOf &apos;hormone biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;angiotensin catabolic process in blood&apos; SubClassOf &apos;results in formation of&apos; some http://purl.obolibrary.org/obo/CHEBI_48433</newAxiom>
<newAxiom>&apos;angiotensin catabolic process in blood&apos; SubClassOf &apos;peptide biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;angiotensin catabolic process in blood&apos; SubClassOf &apos;occurs in&apos; some http://purl.obolibrary.org/obo/UBERON_0000178</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016503</classIRI>
<classLabel>pheromone receptor activity</classLabel>
<deletedAxiom>&apos;pheromone receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/GOCHE_26013)</deletedAxiom>
<newAxiom>&apos;pheromone receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/GOCHE_26013)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016502</classIRI>
<classLabel>nucleotide receptor activity</classLabel>
<deletedAxiom>&apos;nucleotide receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_36976)</deletedAxiom>
<newAxiom>&apos;nucleotide receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_36976)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016501</classIRI>
<classLabel>prostacyclin receptor activity</classLabel>
<deletedAxiom>&apos;prostacyclin receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15552)</deletedAxiom>
<newAxiom>&apos;prostacyclin receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15552)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016500</classIRI>
<classLabel>protein-hormone receptor activity</classLabel>
<deletedAxiom>&apos;protein-hormone receptor activity&apos; SubClassOf &apos;receptor activity&apos;</deletedAxiom>
<newAxiom>&apos;protein-hormone receptor activity&apos; SubClassOf &apos;signaling receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016515</classIRI>
<classLabel>interleukin-13 receptor activity</classLabel>
<deletedAxiom>&apos;interleukin-13 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001370)</deletedAxiom>
<newAxiom>&apos;interleukin-13 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001370)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016520</classIRI>
<classLabel>growth hormone-releasing hormone receptor activity</classLabel>
<deletedAxiom>&apos;growth hormone-releasing hormone receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000007971)</deletedAxiom>
<newAxiom>&apos;growth hormone-releasing hormone receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000007971)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016499</classIRI>
<classLabel>orexin receptor activity</classLabel>
<deletedAxiom>&apos;orexin receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000008476)</deletedAxiom>
<newAxiom>&apos;orexin receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000008476)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031963</classIRI>
<classLabel>cortisol receptor activity</classLabel>
<deletedAxiom>&apos;cortisol receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17650)</deletedAxiom>
<newAxiom>&apos;cortisol receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17650)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031955</classIRI>
<classLabel>short-chain fatty acid-CoA ligase activity</classLabel>
<newAxiom>&apos;short-chain fatty acid-CoA ligase activity&apos; SubClassOf &apos;CoA-ligase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031957</classIRI>
<classLabel>very long-chain fatty acid-CoA ligase activity</classLabel>
<newAxiom>&apos;very long-chain fatty acid-CoA ligase activity&apos; SubClassOf &apos;CoA-ligase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031956</classIRI>
<classLabel>medium-chain fatty acid-CoA ligase activity</classLabel>
<newAxiom>&apos;medium-chain fatty acid-CoA ligase activity&apos; SubClassOf &apos;CoA-ligase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903962</classIRI>
<classLabel>arachidonate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;arachidonate transmembrane transporter activity&apos; SubClassOf &apos;monocarboxylic acid transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;arachidonate transmembrane transporter activity&apos; SubClassOf &apos;fatty acid transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016167</classIRI>
<classLabel>glial cell-derived neurotrophic factor receptor activity</classLabel>
<deletedAxiom>&apos;glial cell-derived neurotrophic factor receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000007928)</deletedAxiom>
<newAxiom>&apos;glial cell-derived neurotrophic factor receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000007928)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016019</classIRI>
<classLabel>peptidoglycan receptor activity</classLabel>
<deletedAxiom>&apos;peptidoglycan receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_8005)</deletedAxiom>
<newAxiom>&apos;peptidoglycan receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_8005)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031650</classIRI>
<classLabel>regulation of heat generation</classLabel>
<deletedAxiom>&apos;regulation of heat generation&apos; SubClassOf &apos;regulation of homeostatic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of heat generation&apos; SubClassOf &apos;regulation of biological quality&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031652</classIRI>
<classLabel>positive regulation of heat generation</classLabel>
<deletedAxiom>&apos;positive regulation of heat generation&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031651</classIRI>
<classLabel>negative regulation of heat generation</classLabel>
<deletedAxiom>&apos;negative regulation of heat generation&apos; SubClassOf &apos;negative regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031654</classIRI>
<classLabel>regulation of heat dissipation</classLabel>
<deletedAxiom>&apos;regulation of heat dissipation&apos; SubClassOf &apos;regulation of homeostatic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of heat dissipation&apos; SubClassOf &apos;regulation of biological quality&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031656</classIRI>
<classLabel>positive regulation of heat dissipation</classLabel>
<deletedAxiom>&apos;positive regulation of heat dissipation&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031655</classIRI>
<classLabel>negative regulation of heat dissipation</classLabel>
<deletedAxiom>&apos;negative regulation of heat dissipation&apos; SubClassOf &apos;negative regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070915</classIRI>
<classLabel>lysophosphatidic acid receptor activity</classLabel>
<deletedAxiom>&apos;lysophosphatidic acid receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_52288)</deletedAxiom>
<newAxiom>&apos;lysophosphatidic acid receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_52288)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070892</classIRI>
<classLabel>lipoteichoic acid receptor activity</classLabel>
<deletedAxiom>&apos;lipoteichoic acid receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_28640)</deletedAxiom>
<newAxiom>&apos;lipoteichoic acid receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_28640)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006201</classIRI>
<classLabel>GMP catabolic process to IMP</classLabel>
<deletedAxiom>&apos;GMP catabolic process to IMP&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17202</deletedAxiom>
<deletedAxiom>&apos;GMP catabolic process to IMP&apos; SubClassOf &apos;IMP metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;GMP catabolic process to IMP&apos; SubClassOf &apos;IMP biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006202</classIRI>
<classLabel>GMP catabolic process to guanine</classLabel>
<deletedAxiom>&apos;GMP catabolic process to guanine&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16235</deletedAxiom>
<deletedAxiom>&apos;GMP catabolic process to guanine&apos; SubClassOf &apos;guanine metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;GMP catabolic process to guanine&apos; SubClassOf &apos;guanine biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045821</classIRI>
<classLabel>positive regulation of glycolytic process</classLabel>
<deletedAxiom>&apos;positive regulation of glycolytic process&apos; SubClassOf &apos;positive regulation of ATP metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of glycolytic process&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of glycolytic process&apos; SubClassOf &apos;positive regulation of ATP biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;positive regulation of glycolytic process&apos; SubClassOf &apos;positive regulation of nucleotide catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045820</classIRI>
<classLabel>negative regulation of glycolytic process</classLabel>
<deletedAxiom>&apos;negative regulation of glycolytic process&apos; SubClassOf &apos;negative regulation of catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of glycolytic process&apos; SubClassOf &apos;negative regulation of ATP metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of glycolytic process&apos; SubClassOf &apos;negative regulation of ATP biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;negative regulation of glycolytic process&apos; SubClassOf &apos;negative regulation of nucleotide catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070811</classIRI>
<classLabel>glycerol-2-phosphate transport</classLabel>
<deletedAxiom>&apos;glycerol-2-phosphate transport&apos; EquivalentTo &apos;transport&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_17270)</deletedAxiom>
<newAxiom>&apos;glycerol-2-phosphate transport&apos; EquivalentTo &apos;transport&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_17270) and (&apos;results in transport across&apos; some &apos;membrane&apos;)</newAxiom>
<newAxiom>&apos;glycerol-2-phosphate transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045780</classIRI>
<classLabel>positive regulation of bone resorption</classLabel>
<deletedAxiom>&apos;positive regulation of bone resorption&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045779</classIRI>
<classLabel>negative regulation of bone resorption</classLabel>
<deletedAxiom>&apos;negative regulation of bone resorption&apos; SubClassOf &apos;negative regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0080158</classIRI>
<classLabel>chloroplast ribulose bisphosphate carboxylase complex biogenesis</classLabel>
<deletedAxiom>&apos;chloroplast ribulose bisphosphate carboxylase complex biogenesis&apos; SubClassOf &apos;protein complex biogenesis&apos;</deletedAxiom>
<newAxiom>&apos;chloroplast ribulose bisphosphate carboxylase complex biogenesis&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006110</classIRI>
<classLabel>regulation of glycolytic process</classLabel>
<deletedAxiom>&apos;regulation of glycolytic process&apos; SubClassOf &apos;regulation of ATP metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of glycolytic process&apos; SubClassOf &apos;regulation of ATP biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;regulation of glycolytic process&apos; SubClassOf &apos;regulation of nucleotide catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006150</classIRI>
<classLabel>hypoxanthine oxidation</classLabel>
<deletedAxiom>&apos;hypoxanthine oxidation&apos; SubClassOf &apos;oxidation-reduction process&apos;</deletedAxiom>
<newAxiom>&apos;hypoxanthine oxidation&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has_part&apos; some &apos;oxidation-reduction process&apos;) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17368)</newAxiom>
<newAxiom>&apos;hypoxanthine oxidation&apos; SubClassOf &apos;has_part&apos; some &apos;oxidation-reduction process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006096</classIRI>
<classLabel>glycolytic process</classLabel>
<deletedAxiom>&apos;glycolytic process&apos; SubClassOf &apos;pyruvate metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;glycolytic process&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15361</deletedAxiom>
<deletedAxiom>&apos;glycolytic process&apos; SubClassOf &apos;nicotinamide nucleotide metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;glycolytic process&apos; SubClassOf &apos;pyruvate biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;glycolytic process&apos; SubClassOf &apos;nucleotide catabolic process&apos;</newAxiom>
<newAxiom>&apos;glycolytic process&apos; SubClassOf &apos;ATP biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;glycolytic process&apos; SubClassOf &apos;nicotinamide nucleotide biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045646</classIRI>
<classLabel>regulation of erythrocyte differentiation</classLabel>
<deletedAxiom>&apos;regulation of erythrocyte differentiation&apos; SubClassOf &apos;regulation of homeostatic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of erythrocyte differentiation&apos; SubClassOf &apos;regulation of biological quality&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045648</classIRI>
<classLabel>positive regulation of erythrocyte differentiation</classLabel>
<deletedAxiom>&apos;positive regulation of erythrocyte differentiation&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045647</classIRI>
<classLabel>negative regulation of erythrocyte differentiation</classLabel>
<deletedAxiom>&apos;negative regulation of erythrocyte differentiation&apos; SubClassOf &apos;negative regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033568</classIRI>
<classLabel>lactoferrin receptor activity</classLabel>
<deletedAxiom>&apos;lactoferrin receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000009978)</deletedAxiom>
<newAxiom>&apos;lactoferrin receptor activity&apos; EquivalentTo &apos;cargo receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000009978)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008502</classIRI>
<classLabel>melatonin receptor activity</classLabel>
<deletedAxiom>&apos;melatonin receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_16796)</deletedAxiom>
<newAxiom>&apos;melatonin receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_16796)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008503</classIRI>
<classLabel>benzodiazepine receptor activity</classLabel>
<deletedAxiom>&apos;benzodiazepine receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_22720)</deletedAxiom>
<newAxiom>&apos;benzodiazepine receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_22720)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008565</classIRI>
<classLabel>protein transporter activity</classLabel>
<deletedAxiom>&apos;protein transporter activity&apos; SubClassOf &apos;peptide transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;protein transporter activity&apos; SubClassOf &apos;transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033516</classIRI>
<classLabel>L-methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine</classLabel>
<newAxiom>&apos;L-methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_15961) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15699) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16643)</newAxiom>
<newAxiom>&apos;L-methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine&apos; SubClassOf &apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_15961</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008588</classIRI>
<classLabel>release of cytoplasmic sequestered NF-kappaB</classLabel>
<deletedAxiom>&apos;release of cytoplasmic sequestered NF-kappaB&apos; SubClassOf &apos;regulation of biological quality&apos;</deletedAxiom>
<deletedAxiom>&apos;release of cytoplasmic sequestered NF-kappaB&apos; SubClassOf &apos;part of&apos; some &apos;I-kappaB kinase/NF-kappaB signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;release of cytoplasmic sequestered NF-kappaB&apos; SubClassOf &apos;negative regulation of biological process&apos;</deletedAxiom>
<deletedAxiom>&apos;release of cytoplasmic sequestered NF-kappaB&apos; SubClassOf &apos;positive regulation of NF-kappaB import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;release of cytoplasmic sequestered NF-kappaB&apos; SubClassOf &apos;negatively regulates&apos; some &apos;cytoplasmic sequestering of NF-kappaB&apos;</deletedAxiom>
<newAxiom>&apos;release of cytoplasmic sequestered NF-kappaB&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008434</classIRI>
<classLabel>calcitriol receptor activity</classLabel>
<deletedAxiom>&apos;calcitriol receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17823)</deletedAxiom>
<newAxiom>&apos;calcitriol receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17823)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033362</classIRI>
<classLabel>lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway</classLabel>
<newAxiom>&apos;lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has_part&apos; some &apos;diaminopimelate epimerase activity&apos;) and (&apos;has_part&apos; some &apos;L,L-diaminopimelate aminotransferase activity&apos;) and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_23671) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_32563)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033361</classIRI>
<classLabel>lysine biosynthetic process via diaminopimelate, dehydrogenase pathway</classLabel>
<newAxiom>&apos;lysine biosynthetic process via diaminopimelate, dehydrogenase pathway&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has_part&apos; some &apos;diaminopimelate dehydrogenase activity&apos;) and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_23671) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_32563)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008320</classIRI>
<classLabel>protein transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;protein transmembrane transporter activity&apos; EquivalentTo &apos;transmembrane transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/PR_000000001)</deletedAxiom>
<newAxiom>&apos;protein transmembrane transporter activity&apos; EquivalentTo &apos;transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/PR_000000001) and (&apos;results in transport across&apos; some &apos;membrane&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008329</classIRI>
<classLabel>signaling pattern recognition receptor activity</classLabel>
<deletedAxiom>&apos;signaling pattern recognition receptor activity&apos; SubClassOf &apos;signaling receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008281</classIRI>
<classLabel>sulfonylurea receptor activity</classLabel>
<deletedAxiom>&apos;sulfonylurea receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_26831)</deletedAxiom>
<newAxiom>&apos;sulfonylurea receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_26831)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008226</classIRI>
<classLabel>tyramine receptor activity</classLabel>
<deletedAxiom>&apos;tyramine receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15760)</deletedAxiom>
<newAxiom>&apos;tyramine receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15760)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008066</classIRI>
<classLabel>glutamate receptor activity</classLabel>
<deletedAxiom>&apos;glutamate receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987)</deletedAxiom>
<newAxiom>&apos;glutamate receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033029</classIRI>
<classLabel>regulation of neutrophil apoptotic process</classLabel>
<deletedAxiom>&apos;regulation of neutrophil apoptotic process&apos; SubClassOf &apos;regulation of homeostatic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of neutrophil apoptotic process&apos; SubClassOf &apos;regulation of biological quality&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033031</classIRI>
<classLabel>positive regulation of neutrophil apoptotic process</classLabel>
<deletedAxiom>&apos;positive regulation of neutrophil apoptotic process&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033030</classIRI>
<classLabel>negative regulation of neutrophil apoptotic process</classLabel>
<deletedAxiom>&apos;negative regulation of neutrophil apoptotic process&apos; SubClassOf &apos;negative regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033025</classIRI>
<classLabel>regulation of mast cell apoptotic process</classLabel>
<deletedAxiom>&apos;regulation of mast cell apoptotic process&apos; SubClassOf &apos;regulation of homeostatic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of mast cell apoptotic process&apos; SubClassOf &apos;regulation of biological quality&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033027</classIRI>
<classLabel>positive regulation of mast cell apoptotic process</classLabel>
<deletedAxiom>&apos;positive regulation of mast cell apoptotic process&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033026</classIRI>
<classLabel>negative regulation of mast cell apoptotic process</classLabel>
<deletedAxiom>&apos;negative regulation of mast cell apoptotic process&apos; SubClassOf &apos;negative regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072317</classIRI>
<classLabel>glucan endo-1,3-beta-D-glucosidase activity involved in ascospore release from ascus</classLabel>
<deletedAxiom>&apos;glucan endo-1,3-beta-D-glucosidase activity involved in ascospore release from ascus&apos; EquivalentTo &apos;glucan endo-1,3-beta-D-glucosidase activity&apos; and (&apos;part of&apos; some &apos;ascospore release from ascus&apos;)</deletedAxiom>
<deletedAxiom>&apos;glucan endo-1,3-beta-D-glucosidase activity involved in ascospore release from ascus&apos; SubClassOf &apos;part of&apos; some &apos;(1-3)-beta-D-glucan catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;glucan endo-1,3-beta-D-glucosidase activity involved in ascospore release from ascus&apos; SubClassOf &apos;part of&apos; some &apos;extracellular polysaccharide catabolic process involved in ascospore release from ascus&apos;</deletedAxiom>
<deletedAxiom>&apos;glucan endo-1,3-beta-D-glucosidase activity involved in ascospore release from ascus&apos; SubClassOf &apos;glucan endo-1,3-beta-D-glucosidase activity&apos;</deletedAxiom>
<newAxiom>&apos;glucan endo-1,3-beta-D-glucosidase activity involved in ascospore release from ascus&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106042</classIRI>
<classLabel>negative regulation of GABA-A receptor activity</classLabel>
<deletedAxiom>&apos;negative regulation of GABA-A receptor activity&apos; SubClassOf &apos;negative regulation of signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106041</classIRI>
<classLabel>positive regulation of GABA-A receptor activity</classLabel>
<deletedAxiom>&apos;positive regulation of GABA-A receptor activity&apos; SubClassOf &apos;positive regulation of signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003708</classIRI>
<classLabel>retinoic acid receptor activity</classLabel>
<deletedAxiom>&apos;retinoic acid receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_26536)</deletedAxiom>
<newAxiom>&apos;retinoic acid receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_26536)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003707</classIRI>
<classLabel>steroid hormone receptor activity</classLabel>
<deletedAxiom>&apos;steroid hormone receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_26764)</deletedAxiom>
<newAxiom>&apos;steroid hormone receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_26764)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902094</classIRI>
<classLabel>regulation of cartilage homeostasis</classLabel>
<deletedAxiom>&apos;regulation of cartilage homeostasis&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;cartilage homeostasis&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of cartilage homeostasis&apos; SubClassOf &apos;regulates&apos; some &apos;cartilage homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cartilage homeostasis&apos; SubClassOf &apos;regulation of multicellular organismal process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cartilage homeostasis&apos; SubClassOf &apos;regulation of homeostatic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of cartilage homeostasis&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902096</classIRI>
<classLabel>positive regulation of cartilage homeostasis</classLabel>
<deletedAxiom>&apos;positive regulation of cartilage homeostasis&apos; SubClassOf &apos;positively regulates&apos; some &apos;cartilage homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cartilage homeostasis&apos; SubClassOf &apos;regulation of cartilage homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cartilage homeostasis&apos; SubClassOf &apos;positive regulation of multicellular organismal process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cartilage homeostasis&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;cartilage homeostasis&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cartilage homeostasis&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of cartilage homeostasis&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902095</classIRI>
<classLabel>negative regulation of cartilage homeostasis</classLabel>
<deletedAxiom>&apos;negative regulation of cartilage homeostasis&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;cartilage homeostasis&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cartilage homeostasis&apos; SubClassOf &apos;negative regulation of multicellular organismal process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cartilage homeostasis&apos; SubClassOf &apos;negative regulation of homeostatic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cartilage homeostasis&apos; SubClassOf &apos;regulation of cartilage homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cartilage homeostasis&apos; SubClassOf &apos;negatively regulates&apos; some &apos;cartilage homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of cartilage homeostasis&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042994</classIRI>
<classLabel>cytoplasmic sequestering of transcription factor</classLabel>
<deletedAxiom>&apos;cytoplasmic sequestering of transcription factor&apos; SubClassOf &apos;negative regulation of transcription factor import into nucleus&apos;</deletedAxiom>
<newAxiom>&apos;cytoplasmic sequestering of transcription factor&apos; SubClassOf &apos;negative regulation of DNA binding transcription factor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042993</classIRI>
<classLabel>positive regulation of transcription factor import into nucleus</classLabel>
<deletedAxiom>&apos;positive regulation of transcription factor import into nucleus&apos; SubClassOf &apos;regulation of transcription factor import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription factor import into nucleus&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;transcription factor import into nucleus&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription factor import into nucleus&apos; SubClassOf &apos;positive regulation of protein import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription factor import into nucleus&apos; SubClassOf &apos;positively regulates&apos; some &apos;transcription factor import into nucleus&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of transcription factor import into nucleus&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042992</classIRI>
<classLabel>negative regulation of transcription factor import into nucleus</classLabel>
<deletedAxiom>&apos;negative regulation of transcription factor import into nucleus&apos; SubClassOf &apos;negative regulation of protein import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription factor import into nucleus&apos; SubClassOf &apos;regulation of transcription factor import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription factor import into nucleus&apos; SubClassOf &apos;negatively regulates&apos; some &apos;transcription factor import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription factor import into nucleus&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;transcription factor import into nucleus&apos;)</deletedAxiom>
<newAxiom>&apos;negative regulation of transcription factor import into nucleus&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042991</classIRI>
<classLabel>transcription factor import into nucleus</classLabel>
<deletedAxiom>&apos;transcription factor import into nucleus&apos; SubClassOf &apos;protein import into nucleus&apos;</deletedAxiom>
<newAxiom>&apos;transcription factor import into nucleus&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042990</classIRI>
<classLabel>regulation of transcription factor import into nucleus</classLabel>
<deletedAxiom>&apos;regulation of transcription factor import into nucleus&apos; SubClassOf &apos;regulates&apos; some &apos;transcription factor import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription factor import into nucleus&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;transcription factor import into nucleus&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription factor import into nucleus&apos; SubClassOf &apos;regulation of protein import into nucleus&apos;</deletedAxiom>
<newAxiom>&apos;regulation of transcription factor import into nucleus&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003254</classIRI>
<classLabel>regulation of membrane depolarization</classLabel>
<deletedAxiom>&apos;regulation of membrane depolarization&apos; SubClassOf &apos;regulation of ion homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;regulation of membrane depolarization&apos; SubClassOf &apos;ion homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042937</classIRI>
<classLabel>tripeptide transporter activity</classLabel>
<deletedAxiom>&apos;tripeptide transporter activity&apos; EquivalentTo &apos;transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_47923)</deletedAxiom>
<deletedAxiom>&apos;tripeptide transporter activity&apos; SubClassOf &apos;peptide transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;tripeptide transporter activity&apos; SubClassOf &apos;oligopeptide transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;tripeptide transporter activity&apos; EquivalentTo &apos;transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_47923) and (&apos;results in transport across&apos; some &apos;membrane&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042936</classIRI>
<classLabel>dipeptide transporter activity</classLabel>
<deletedAxiom>&apos;dipeptide transporter activity&apos; EquivalentTo &apos;transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_46761)</deletedAxiom>
<deletedAxiom>&apos;dipeptide transporter activity&apos; SubClassOf &apos;part of&apos; some &apos;dipeptide transport&apos;</deletedAxiom>
<deletedAxiom>&apos;dipeptide transporter activity&apos; SubClassOf &apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_46761</deletedAxiom>
<deletedAxiom>&apos;dipeptide transporter activity&apos; SubClassOf &apos;peptide transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;dipeptide transporter activity&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001153</classIRI>
<classLabel>positive regulation of renal water transport</classLabel>
<deletedAxiom>&apos;positive regulation of renal water transport&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001152</classIRI>
<classLabel>negative regulation of renal water transport</classLabel>
<deletedAxiom>&apos;negative regulation of renal water transport&apos; SubClassOf &apos;negative regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001151</classIRI>
<classLabel>regulation of renal water transport</classLabel>
<deletedAxiom>&apos;regulation of renal water transport&apos; SubClassOf &apos;regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042897</classIRI>
<classLabel>polymyxin transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;polymyxin transmembrane transporter activity&apos; EquivalentTo &apos;transmembrane transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_59062)</deletedAxiom>
<newAxiom>&apos;polymyxin transmembrane transporter activity&apos; EquivalentTo &apos;transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_59062) and (&apos;results in transport across&apos; some &apos;membrane&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902661</classIRI>
<classLabel>positive regulation of glucose mediated signaling pathway</classLabel>
<deletedAxiom>&apos;positive regulation of glucose mediated signaling pathway&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902660</classIRI>
<classLabel>negative regulation of glucose mediated signaling pathway</classLabel>
<deletedAxiom>&apos;negative regulation of glucose mediated signaling pathway&apos; SubClassOf &apos;negative regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902659</classIRI>
<classLabel>regulation of glucose mediated signaling pathway</classLabel>
<deletedAxiom>&apos;regulation of glucose mediated signaling pathway&apos; SubClassOf &apos;regulation of homeostatic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of glucose mediated signaling pathway&apos; SubClassOf &apos;regulation of biological quality&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032981</classIRI>
<classLabel>mitochondrial respiratory chain complex I assembly</classLabel>
<deletedAxiom>&apos;mitochondrial respiratory chain complex I assembly&apos; SubClassOf &apos;mitochondrial respiratory chain complex I biogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042348</classIRI>
<classLabel>NF-kappaB import into nucleus</classLabel>
<deletedAxiom>&apos;NF-kappaB import into nucleus&apos; SubClassOf &apos;transcription factor import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;NF-kappaB import into nucleus&apos; SubClassOf &apos;imports&apos; some &apos;NF-kappaB complex&apos;</deletedAxiom>
<deletedAxiom>&apos;NF-kappaB import into nucleus&apos; SubClassOf &apos;protein-containing complex localization&apos;</deletedAxiom>
<deletedAxiom>&apos;NF-kappaB import into nucleus&apos; EquivalentTo &apos;transport&apos; and (&apos;has target start location&apos; some &apos;cytoplasm&apos;) and (&apos;has target end location&apos; some &apos;nucleus&apos;) and (&apos;imports&apos; some &apos;NF-kappaB complex&apos;) and (&apos;results in transport across&apos; some &apos;nuclear envelope&apos;)</deletedAxiom>
<deletedAxiom>&apos;NF-kappaB import into nucleus&apos; SubClassOf &apos;part of&apos; some &apos;I-kappaB kinase/NF-kappaB signaling&apos;</deletedAxiom>
<newAxiom>&apos;NF-kappaB import into nucleus&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042347</classIRI>
<classLabel>negative regulation of NF-kappaB import into nucleus</classLabel>
<deletedAxiom>&apos;negative regulation of NF-kappaB import into nucleus&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;NF-kappaB import into nucleus&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of NF-kappaB import into nucleus&apos; SubClassOf &apos;negatively regulates&apos; some &apos;NF-kappaB import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of NF-kappaB import into nucleus&apos; SubClassOf &apos;negative regulation of I-kappaB kinase/NF-kappaB signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of NF-kappaB import into nucleus&apos; SubClassOf &apos;negative regulation of transcription factor import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of NF-kappaB import into nucleus&apos; SubClassOf &apos;regulation of NF-kappaB import into nucleus&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of NF-kappaB import into nucleus&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042346</classIRI>
<classLabel>positive regulation of NF-kappaB import into nucleus</classLabel>
<deletedAxiom>&apos;positive regulation of NF-kappaB import into nucleus&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;NF-kappaB import into nucleus&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of NF-kappaB import into nucleus&apos; SubClassOf &apos;positive regulation of I-kappaB kinase/NF-kappaB signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of NF-kappaB import into nucleus&apos; SubClassOf &apos;positively regulates&apos; some &apos;NF-kappaB import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of NF-kappaB import into nucleus&apos; SubClassOf &apos;regulation of NF-kappaB import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of NF-kappaB import into nucleus&apos; SubClassOf &apos;positive regulation of transcription factor import into nucleus&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of NF-kappaB import into nucleus&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042345</classIRI>
<classLabel>regulation of NF-kappaB import into nucleus</classLabel>
<deletedAxiom>&apos;regulation of NF-kappaB import into nucleus&apos; SubClassOf &apos;regulation of transcription factor import into nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of NF-kappaB import into nucleus&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;NF-kappaB import into nucleus&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of NF-kappaB import into nucleus&apos; SubClassOf &apos;regulation of I-kappaB kinase/NF-kappaB signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of NF-kappaB import into nucleus&apos; SubClassOf &apos;regulates&apos; some &apos;NF-kappaB import into nucleus&apos;</deletedAxiom>
<newAxiom>&apos;regulation of NF-kappaB import into nucleus&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032849</classIRI>
<classLabel>positive regulation of cellular pH reduction</classLabel>
<deletedAxiom>&apos;positive regulation of cellular pH reduction&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032844</classIRI>
<classLabel>regulation of homeostatic process</classLabel>
<deletedAxiom>&apos;regulation of homeostatic process&apos; SubClassOf &apos;regulates&apos; some &apos;homeostatic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of homeostatic process&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;homeostatic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of homeostatic process&apos; SubClassOf &apos;regulation of biological process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of homeostatic process&apos; SubClassOf &apos;regulation of biological quality&apos;</deletedAxiom>
<newAxiom>&apos;regulation of homeostatic process&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032846</classIRI>
<classLabel>positive regulation of homeostatic process</classLabel>
<deletedAxiom>&apos;positive regulation of homeostatic process&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;homeostatic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of homeostatic process&apos; SubClassOf &apos;regulation of homeostatic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of homeostatic process&apos; SubClassOf &apos;positive regulation of biological process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of homeostatic process&apos; SubClassOf &apos;positively regulates&apos; some &apos;homeostatic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of homeostatic process&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032845</classIRI>
<classLabel>negative regulation of homeostatic process</classLabel>
<deletedAxiom>&apos;negative regulation of homeostatic process&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;homeostatic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of homeostatic process&apos; SubClassOf &apos;negative regulation of biological process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of homeostatic process&apos; SubClassOf &apos;regulation of homeostatic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of homeostatic process&apos; SubClassOf &apos;negatively regulates&apos; some &apos;homeostatic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of homeostatic process&apos; SubClassOf http://www.w3.org/2002/07/owl#Thing</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032848</classIRI>
<classLabel>negative regulation of cellular pH reduction</classLabel>
<deletedAxiom>&apos;negative regulation of cellular pH reduction&apos; SubClassOf &apos;negative regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032847</classIRI>
<classLabel>regulation of cellular pH reduction</classLabel>
<deletedAxiom>&apos;regulation of cellular pH reduction&apos; SubClassOf &apos;regulation of ion homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017132</classIRI>
<classLabel>cAMP-dependent guanyl-nucleotide exchange factor activity</classLabel>
<deletedAxiom>&apos;cAMP-dependent guanyl-nucleotide exchange factor activity&apos; SubClassOf &apos;molecular transducer activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017154</classIRI>
<classLabel>semaphorin receptor activity</classLabel>
<deletedAxiom>&apos;semaphorin receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001926)</deletedAxiom>
<newAxiom>&apos;semaphorin receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001926)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042103</classIRI>
<classLabel>positive regulation of T cell homeostatic proliferation</classLabel>
<deletedAxiom>&apos;positive regulation of T cell homeostatic proliferation&apos; SubClassOf &apos;positive regulation of homeostatic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017082</classIRI>
<classLabel>mineralocorticoid receptor activity</classLabel>
<deletedAxiom>&apos;mineralocorticoid receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_25354)</deletedAxiom>
<newAxiom>&apos;mineralocorticoid receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_25354)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042018</classIRI>
<classLabel>interleukin-22 receptor activity</classLabel>
<deletedAxiom>&apos;interleukin-22 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001383)</deletedAxiom>
<newAxiom>&apos;interleukin-22 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001383)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042016</classIRI>
<classLabel>interleukin-20 receptor activity</classLabel>
<deletedAxiom>&apos;interleukin-20 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001473)</deletedAxiom>
<newAxiom>&apos;interleukin-20 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001473)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042014</classIRI>
<classLabel>interleukin-19 receptor activity</classLabel>
<deletedAxiom>&apos;interleukin-19 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001472)</deletedAxiom>
<newAxiom>&apos;interleukin-19 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001472)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042012</classIRI>
<classLabel>interleukin-16 receptor activity</classLabel>
<deletedAxiom>&apos;interleukin-16 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001374)</deletedAxiom>
<newAxiom>&apos;interleukin-16 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001374)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042010</classIRI>
<classLabel>interleukin-15 receptor activity</classLabel>
<deletedAxiom>&apos;interleukin-15 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001373)</deletedAxiom>
<newAxiom>&apos;interleukin-15 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001373)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042008</classIRI>
<classLabel>interleukin-18 receptor activity</classLabel>
<deletedAxiom>&apos;interleukin-18 receptor activity&apos; EquivalentTo &apos;receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001376)</deletedAxiom>
<newAxiom>&apos;interleukin-18 receptor activity&apos; EquivalentTo &apos;signaling receptor activity&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/PR_000001376)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046939</classIRI>
<classLabel>nucleotide phosphorylation</classLabel>
<newAxiom>&apos;nucleotide phosphorylation&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_36976</newAxiom>
<newAxiom>&apos;nucleotide phosphorylation&apos; EquivalentTo &apos;phosphorylation&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_36976)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071916</classIRI>
<classLabel>dipeptide transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;dipeptide transmembrane transporter activity&apos; SubClassOf &apos;dipeptide transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;dipeptide transmembrane transporter activity&apos; EquivalentTo &apos;transmembrane transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_46761)</deletedAxiom>
<newAxiom>&apos;dipeptide transmembrane transporter activity&apos; SubClassOf &apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_46761</newAxiom>
<newAxiom>&apos;dipeptide transmembrane transporter activity&apos; EquivalentTo &apos;transporter activity&apos; and (&apos;transports or maintains localization of&apos; some http://purl.obolibrary.org/obo/CHEBI_46761) and (&apos;results in transport across&apos; some &apos;membrane&apos;)</newAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103016</classIRI>
<classLabel>tRNA-specific 2-thiouridylase activity</classLabel>
<newAxiom>'tRNA-specific 2-thiouridylase activity' SubClassOf 'ligase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102028</classIRI>
<classLabel>cystathionine gamma-synthase activity (acts on O-phosphohomoserine)</classLabel>
<newAxiom>'cystathionine gamma-synthase activity (acts on O-phosphohomoserine)' SubClassOf 'transferase activity, transferring alkyl or aryl (other than methyl) groups'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102029</classIRI>
<classLabel>D-lactate dehydrogenase (quinone) activity</classLabel>
<newAxiom>'D-lactate dehydrogenase (quinone) activity' SubClassOf 'oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102041</classIRI>
<classLabel>7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase</classLabel>
<newAxiom>'7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase' SubClassOf 'transferase activity, transferring alkyl or aryl (other than methyl) groups'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102016</classIRI>
<classLabel>nickel ABC transporter activity</classLabel>
<newAxiom>'nickel ABC transporter activity' SubClassOf 'ATPase activity, coupled to transmembrane movement of substances'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120133</classIRI>
<classLabel>negative regulation of actin cortical patch assembly</classLabel>
<newAxiom>'negative regulation of actin cortical patch assembly' SubClassOf 'regulation of actin cytoskeleton organization'</newAxiom>
<newAxiom>'negative regulation of actin cortical patch assembly' EquivalentTo 'biological_process' and ('negatively regulates' some 'actin cortical patch assembly')</newAxiom>
<newAxiom>'negative regulation of actin cortical patch assembly' SubClassOf 'regulation of cellular component biogenesis'</newAxiom>
<newAxiom>'negative regulation of actin cortical patch assembly' SubClassOf 'negative regulation of cytoskeleton organization'</newAxiom>
<newAxiom>'negative regulation of actin cortical patch assembly' SubClassOf 'negatively regulates' some 'actin cortical patch assembly'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110098</classIRI>
<classLabel>positive regulation of calcium import into the mitochondrion</classLabel>
<newAxiom>'positive regulation of calcium import into the mitochondrion' SubClassOf 'positively regulates' some 'calcium import into the mitochondrion'</newAxiom>
<newAxiom>'positive regulation of calcium import into the mitochondrion' SubClassOf 'regulation of calcium import into the mitochondrion'</newAxiom>
<newAxiom>'positive regulation of calcium import into the mitochondrion' SubClassOf 'positive regulation of calcium ion transmembrane transport'</newAxiom>
<newAxiom>'positive regulation of calcium import into the mitochondrion' SubClassOf 'positive regulation of calcium ion import'</newAxiom>
<newAxiom>'positive regulation of calcium import into the mitochondrion' EquivalentTo 'biological regulation' and ('positively regulates' some 'calcium import into the mitochondrion')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110097</classIRI>
<classLabel>regulation of calcium import into the mitochondrion</classLabel>
<newAxiom>'regulation of calcium import into the mitochondrion' SubClassOf 'regulation of calcium ion import'</newAxiom>
<newAxiom>'regulation of calcium import into the mitochondrion' SubClassOf 'regulation of calcium ion transmembrane transport'</newAxiom>
<newAxiom>'regulation of calcium import into the mitochondrion' SubClassOf 'regulates' some 'calcium import into the mitochondrion'</newAxiom>
<newAxiom>'regulation of calcium import into the mitochondrion' EquivalentTo 'biological regulation' and ('regulates' some 'calcium import into the mitochondrion')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110099</classIRI>
<classLabel>negative regulation of calcium import into the mitochondrion</classLabel>
<newAxiom>'negative regulation of calcium import into the mitochondrion' SubClassOf 'negative regulation of calcium ion import'</newAxiom>
<newAxiom>'negative regulation of calcium import into the mitochondrion' SubClassOf 'negatively regulates' some 'calcium import into the mitochondrion'</newAxiom>
<newAxiom>'negative regulation of calcium import into the mitochondrion' EquivalentTo 'biological regulation' and ('negatively regulates' some 'calcium import into the mitochondrion')</newAxiom>
<newAxiom>'negative regulation of calcium import into the mitochondrion' SubClassOf 'regulation of calcium import into the mitochondrion'</newAxiom>
<newAxiom>'negative regulation of calcium import into the mitochondrion' SubClassOf 'negative regulation of calcium ion transmembrane transport'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062011</classIRI>
<classLabel>mitochondrial respiratory chain complex IV pre-assembly complex</classLabel>
<newAxiom>'mitochondrial respiratory chain complex IV pre-assembly complex' SubClassOf 'capable of part of' some 'negative regulation of mitochondrial translation'</newAxiom>
<newAxiom>'mitochondrial respiratory chain complex IV pre-assembly complex' SubClassOf 'capable of part of' some 'mitochondrial respiratory chain complex IV assembly'</newAxiom>
<newAxiom>'mitochondrial respiratory chain complex IV pre-assembly complex' SubClassOf 'inner mitochondrial membrane protein complex'</newAxiom>
<newAxiom>'mitochondrial respiratory chain complex IV pre-assembly complex' SubClassOf 'chaperone complex'</newAxiom>
<newAxiom>'mitochondrial respiratory chain complex IV pre-assembly complex' SubClassOf 'integral component of mitochondrial inner membrane'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062010</classIRI>
<classLabel>primitive palate development</classLabel>
<newAxiom>'primitive palate development' SubClassOf 'roof of mouth development'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062003</classIRI>
<classLabel>negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity</classLabel>
<newAxiom>'negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity' EquivalentTo 'biological_process' and ('negatively regulates' some 'all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity')</newAxiom>
<newAxiom>'negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity' SubClassOf 'negative regulation of hormone metabolic process'</newAxiom>
<newAxiom>'negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity' SubClassOf 'negative regulation of isoprenoid metabolic process'</newAxiom>
<newAxiom>'negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity' SubClassOf 'negative regulation of hydrolase activity'</newAxiom>
<newAxiom>'negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity' SubClassOf 'regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity'</newAxiom>
<newAxiom>'negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity' SubClassOf 'negatively regulates' some 'all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062002</classIRI>
<classLabel>regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity</classLabel>
<newAxiom>'regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity' SubClassOf 'regulation of hydrolase activity'</newAxiom>
<newAxiom>'regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity' SubClassOf 'regulates' some 'all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity'</newAxiom>
<newAxiom>'regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity' EquivalentTo 'biological_process' and ('regulates' some 'all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity')</newAxiom>
<newAxiom>'regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity' SubClassOf 'regulation of isoprenoid metabolic process'</newAxiom>
<newAxiom>'regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity' SubClassOf 'regulation of hormone metabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062009</classIRI>
<classLabel>secondary palate development</classLabel>
<newAxiom>'secondary palate development' SubClassOf 'roof of mouth development'</newAxiom>
<newAxiom>'secondary palate development' SubClassOf 'results in development of' some http://purl.obolibrary.org/obo/UBERON_0001716</newAxiom>
<newAxiom>'secondary palate development' EquivalentTo 'anatomical structure development' and ('results in development of' some http://purl.obolibrary.org/obo/UBERON_0001716)</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140204</classIRI>
<classLabel>pyridoxal import across plasma membrane</classLabel>
<newAxiom>'pyridoxal import across plasma membrane' SubClassOf 'import across plasma membrane'</newAxiom>
<newAxiom>'pyridoxal import across plasma membrane' SubClassOf 'pyridoxal transmembrane transport'</newAxiom>
<newAxiom>'pyridoxal import across plasma membrane' SubClassOf 'imports' some http://purl.obolibrary.org/obo/CHEBI_17310</newAxiom>
<newAxiom>'pyridoxal import across plasma membrane' EquivalentTo 'transport' and ('has target start location' some 'extracellular region') and ('has target end location' some 'cytosol') and ('imports' some http://purl.obolibrary.org/obo/CHEBI_17310) and ('results in transport across' some 'plasma membrane')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140203</classIRI>
<classLabel>spermidine import across plasma membrane</classLabel>
<newAxiom>'spermidine import across plasma membrane' SubClassOf 'imports' some http://purl.obolibrary.org/obo/CHEBI_16610</newAxiom>
<newAxiom>'spermidine import across plasma membrane' SubClassOf 'polyamine import across plasma membrane'</newAxiom>
<newAxiom>'spermidine import across plasma membrane' EquivalentTo 'transport' and ('has target start location' some 'extracellular region') and ('has target end location' some 'cytosol') and ('imports' some http://purl.obolibrary.org/obo/CHEBI_16610) and ('results in transport across' some 'plasma membrane')</newAxiom>
<newAxiom>'spermidine import across plasma membrane' SubClassOf 'ammonium import across plasma membrane'</newAxiom>
<newAxiom>'spermidine import across plasma membrane' SubClassOf 'spermidine transmembrane transport'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140202</classIRI>
<classLabel>polyamine import across plasma membrane</classLabel>
<newAxiom>'polyamine import across plasma membrane' SubClassOf 'imports' some http://purl.obolibrary.org/obo/CHEBI_88061</newAxiom>
<newAxiom>'polyamine import across plasma membrane' EquivalentTo 'transport' and ('has target start location' some 'extracellular region') and ('has target end location' some 'cytosol') and ('imports' some http://purl.obolibrary.org/obo/CHEBI_88061) and ('results in transport across' some 'plasma membrane')</newAxiom>
<newAxiom>'polyamine import across plasma membrane' SubClassOf 'nitrogen compound transport'</newAxiom>
<newAxiom>'polyamine import across plasma membrane' SubClassOf 'organic substance transport'</newAxiom>
<newAxiom>'polyamine import across plasma membrane' SubClassOf 'import across plasma membrane'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140201</classIRI>
<classLabel>urea import across plasma membrane</classLabel>
<newAxiom>'urea import across plasma membrane' SubClassOf 'urea transmembrane transport'</newAxiom>
<newAxiom>'urea import across plasma membrane' EquivalentTo 'transport' and ('has target start location' some 'extracellular region') and ('has target end location' some 'cytosol') and ('imports' some http://purl.obolibrary.org/obo/CHEBI_16199) and ('results in transport across' some 'plasma membrane')</newAxiom>
<newAxiom>'urea import across plasma membrane' SubClassOf 'import across plasma membrane'</newAxiom>
<newAxiom>'urea import across plasma membrane' SubClassOf 'imports' some http://purl.obolibrary.org/obo/CHEBI_16199</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140207</classIRI>
<classLabel>tripeptide import across plasma membrane</classLabel>
<newAxiom>'tripeptide import across plasma membrane' EquivalentTo 'transport' and ('has target start location' some 'extracellular region') and ('has target end location' some 'cytosol') and ('imports' some http://purl.obolibrary.org/obo/CHEBI_47923) and ('results in transport across' some 'plasma membrane')</newAxiom>
<newAxiom>'tripeptide import across plasma membrane' SubClassOf 'imports' some http://purl.obolibrary.org/obo/CHEBI_47923</newAxiom>
<newAxiom>'tripeptide import across plasma membrane' SubClassOf 'tripeptide transmembrane transport'</newAxiom>
<newAxiom>'tripeptide import across plasma membrane' SubClassOf 'oligopeptide import across plasma membrane'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140206</classIRI>
<classLabel>dipeptide import across plasma membrane</classLabel>
<newAxiom>'dipeptide import across plasma membrane' EquivalentTo 'transport' and ('has target start location' some 'extracellular region') and ('has target end location' some 'cytosol') and ('imports' some http://purl.obolibrary.org/obo/CHEBI_46761) and ('results in transport across' some 'plasma membrane')</newAxiom>
<newAxiom>'dipeptide import across plasma membrane' SubClassOf 'oligopeptide import across plasma membrane'</newAxiom>
<newAxiom>'dipeptide import across plasma membrane' SubClassOf 'dipeptide transmembrane transport'</newAxiom>
<newAxiom>'dipeptide import across plasma membrane' SubClassOf 'imports' some http://purl.obolibrary.org/obo/CHEBI_46761</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140205</classIRI>
<classLabel>oligopeptide import across plasma membrane</classLabel>
<newAxiom>'oligopeptide import across plasma membrane' SubClassOf 'import across plasma membrane'</newAxiom>
<newAxiom>'oligopeptide import across plasma membrane' EquivalentTo 'transport' and ('has target start location' some 'extracellular region') and ('has target end location' some 'cytosol') and ('imports' some http://purl.obolibrary.org/obo/CHEBI_25676) and ('results in transport across' some 'plasma membrane')</newAxiom>
<newAxiom>'oligopeptide import across plasma membrane' SubClassOf 'oligopeptide transmembrane transport'</newAxiom>
<newAxiom>'oligopeptide import across plasma membrane' SubClassOf 'imports' some http://purl.obolibrary.org/obo/CHEBI_25676</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>