<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
249
</numberChangedClasses>
<numberNewClasses>
0
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019264</classIRI>
<classLabel>glycine biosynthetic process from serine</classLabel>
<deletedAxiom>&apos;glycine biosynthetic process from serine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32836) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32508)</deletedAxiom>
<deletedAxiom>&apos;glycine biosynthetic process from serine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32836</deletedAxiom>
<newAxiom>&apos;glycine biosynthetic process from serine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32508) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32836)</newAxiom>
<newAxiom>&apos;glycine biosynthetic process from serine&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32836</newAxiom>
<newAxiom>&apos;glycine biosynthetic process from serine&apos; SubClassOf &apos;L-serine metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019266</classIRI>
<classLabel>asparagine biosynthetic process from oxaloacetate</classLabel>
<deletedAxiom>&apos;asparagine biosynthetic process from oxaloacetate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_16452) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32660)</deletedAxiom>
<deletedAxiom>&apos;asparagine biosynthetic process from oxaloacetate&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_16452</deletedAxiom>
<newAxiom>&apos;asparagine biosynthetic process from oxaloacetate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32660) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16452)</newAxiom>
<newAxiom>&apos;asparagine biosynthetic process from oxaloacetate&apos; SubClassOf &apos;oxaloacetate metabolic process&apos;</newAxiom>
<newAxiom>&apos;asparagine biosynthetic process from oxaloacetate&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16452</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019267</classIRI>
<classLabel>asparagine biosynthetic process from cysteine</classLabel>
<deletedAxiom>&apos;asparagine biosynthetic process from cysteine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32458</deletedAxiom>
<deletedAxiom>&apos;asparagine biosynthetic process from cysteine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32458) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32660)</deletedAxiom>
<newAxiom>&apos;asparagine biosynthetic process from cysteine&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32458</newAxiom>
<newAxiom>&apos;asparagine biosynthetic process from cysteine&apos; SubClassOf &apos;cysteine metabolic process&apos;</newAxiom>
<newAxiom>&apos;asparagine biosynthetic process from cysteine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32660) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32458)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019279</classIRI>
<classLabel>L-methionine biosynthetic process from L-homoserine via cystathionine</classLabel>
<deletedAxiom>&apos;L-methionine biosynthetic process from L-homoserine via cystathionine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15699</deletedAxiom>
<deletedAxiom>&apos;L-methionine biosynthetic process from L-homoserine via cystathionine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_17755) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15699) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16643)</deletedAxiom>
<newAxiom>&apos;L-methionine biosynthetic process from L-homoserine via cystathionine&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15699</newAxiom>
<newAxiom>&apos;L-methionine biosynthetic process from L-homoserine via cystathionine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_17755) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16643) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15699)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019272</classIRI>
<classLabel>L-alanine biosynthetic process from pyruvate</classLabel>
<deletedAxiom>&apos;L-alanine biosynthetic process from pyruvate&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15361</deletedAxiom>
<deletedAxiom>&apos;L-alanine biosynthetic process from pyruvate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15361) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32431)</deletedAxiom>
<newAxiom>&apos;L-alanine biosynthetic process from pyruvate&apos; SubClassOf &apos;pyruvate metabolic process&apos;</newAxiom>
<newAxiom>&apos;L-alanine biosynthetic process from pyruvate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32431) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15361)</newAxiom>
<newAxiom>&apos;L-alanine biosynthetic process from pyruvate&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15361</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019285</classIRI>
<classLabel>glycine betaine biosynthetic process from choline</classLabel>
<deletedAxiom>&apos;glycine betaine biosynthetic process from choline&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15354</deletedAxiom>
<deletedAxiom>&apos;glycine betaine biosynthetic process from choline&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15354) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17750)</deletedAxiom>
<newAxiom>&apos;glycine betaine biosynthetic process from choline&apos; SubClassOf &apos;choline metabolic process&apos;</newAxiom>
<newAxiom>&apos;glycine betaine biosynthetic process from choline&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15354</newAxiom>
<newAxiom>&apos;glycine betaine biosynthetic process from choline&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17750) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15354)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019286</classIRI>
<classLabel>glycine betaine biosynthetic process from glycine</classLabel>
<deletedAxiom>&apos;glycine betaine biosynthetic process from glycine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32508</deletedAxiom>
<deletedAxiom>&apos;glycine betaine biosynthetic process from glycine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32508) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17750)</deletedAxiom>
<newAxiom>&apos;glycine betaine biosynthetic process from glycine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17750) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32508)</newAxiom>
<newAxiom>&apos;glycine betaine biosynthetic process from glycine&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32508</newAxiom>
<newAxiom>&apos;glycine betaine biosynthetic process from glycine&apos; SubClassOf &apos;glycine metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019283</classIRI>
<classLabel>L-methionine biosynthetic process from O-phospho-L-homoserine and cystathionine</classLabel>
<deletedAxiom>&apos;L-methionine biosynthetic process from O-phospho-L-homoserine and cystathionine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15961</deletedAxiom>
<deletedAxiom>&apos;L-methionine biosynthetic process from O-phospho-L-homoserine and cystathionine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17755</deletedAxiom>
<deletedAxiom>&apos;L-methionine biosynthetic process from O-phospho-L-homoserine and cystathionine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15961) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17755) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16643)</deletedAxiom>
<newAxiom>&apos;L-methionine biosynthetic process from O-phospho-L-homoserine and cystathionine&apos; SubClassOf &apos;organophosphate metabolic process&apos;</newAxiom>
<newAxiom>&apos;L-methionine biosynthetic process from O-phospho-L-homoserine and cystathionine&apos; SubClassOf &apos;phosphate-containing compound metabolic process&apos;</newAxiom>
<newAxiom>&apos;L-methionine biosynthetic process from O-phospho-L-homoserine and cystathionine&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17755</newAxiom>
<newAxiom>&apos;L-methionine biosynthetic process from O-phospho-L-homoserine and cystathionine&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15961</newAxiom>
<newAxiom>&apos;L-methionine biosynthetic process from O-phospho-L-homoserine and cystathionine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16643) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15961) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17755)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019292</classIRI>
<classLabel>tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate</classLabel>
<deletedAxiom>&apos;tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_36242) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_29748) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_18186)</deletedAxiom>
<deletedAxiom>&apos;tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_29748</deletedAxiom>
<newAxiom>&apos;tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29748</newAxiom>
<newAxiom>&apos;tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate&apos; SubClassOf &apos;chorismate metabolic process&apos;</newAxiom>
<newAxiom>&apos;tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_36242) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_18186) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29748)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019243</classIRI>
<classLabel>methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione</classLabel>
<deletedAxiom>&apos;methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;starts with&apos; some &apos;lactoylglutathione lyase activity&apos;) and (&apos;ends with&apos; some &apos;hydroxyacylglutathione hydrolase activity&apos;) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16004) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17158)</deletedAxiom>
<deletedAxiom>&apos;methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16004</deletedAxiom>
<newAxiom>&apos;methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;starts with&apos; some &apos;lactoylglutathione lyase activity&apos;) and (&apos;ends with&apos; some &apos;hydroxyacylglutathione hydrolase activity&apos;) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16004) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17158)</newAxiom>
<newAxiom>&apos;methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16004</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019244</classIRI>
<classLabel>lactate biosynthetic process from pyruvate</classLabel>
<deletedAxiom>&apos;lactate biosynthetic process from pyruvate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has part&apos; some &apos;lactate dehydrogenase activity&apos;) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15361) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_24996)</deletedAxiom>
<deletedAxiom>&apos;lactate biosynthetic process from pyruvate&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15361</deletedAxiom>
<newAxiom>&apos;lactate biosynthetic process from pyruvate&apos; SubClassOf &apos;pyruvate metabolic process&apos;</newAxiom>
<newAxiom>&apos;lactate biosynthetic process from pyruvate&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15361</newAxiom>
<newAxiom>&apos;lactate biosynthetic process from pyruvate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has part&apos; some &apos;lactate dehydrogenase activity&apos;) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_24996) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15361)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019245</classIRI>
<classLabel>D(-)-lactate biosynthetic process from pyruvate</classLabel>
<deletedAxiom>&apos;D(-)-lactate biosynthetic process from pyruvate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has part&apos; some &apos;D-lactate dehydrogenase activity&apos;) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15361) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16004)</deletedAxiom>
<newAxiom>&apos;D(-)-lactate biosynthetic process from pyruvate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has part&apos; some &apos;D-lactate dehydrogenase activity&apos;) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16004) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15361)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019246</classIRI>
<classLabel>L(+)-lactate biosynthetic process from pyruvate</classLabel>
<deletedAxiom>&apos;L(+)-lactate biosynthetic process from pyruvate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has part&apos; some &apos;L-lactate dehydrogenase activity&apos;) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15361) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16651)</deletedAxiom>
<newAxiom>&apos;L(+)-lactate biosynthetic process from pyruvate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has part&apos; some &apos;L-lactate dehydrogenase activity&apos;) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16651) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15361)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019248</classIRI>
<classLabel>D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde</classLabel>
<deletedAxiom>&apos;D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_17167) and (&apos;starts with&apos; some &apos;methylglyoxal reductase (NADH-dependent) activity&apos;) and (&apos;ends with&apos; some &apos;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor&apos;) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17158) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16004)</deletedAxiom>
<deletedAxiom>&apos;D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17158</deletedAxiom>
<newAxiom>&apos;D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_17167) and (&apos;starts with&apos; some &apos;methylglyoxal reductase (NADH-dependent) activity&apos;) and (&apos;ends with&apos; some &apos;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor&apos;) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16004) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17158)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009777</classIRI>
<classLabel>photosynthetic phosphorylation</classLabel>
<newAxiom>&apos;photosynthetic phosphorylation&apos; SubClassOf &apos;ATP metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009435</classIRI>
<classLabel>NAD biosynthetic process</classLabel>
<deletedAxiom>&apos;NAD biosynthetic process&apos; SubClassOf &apos;NAD metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000954</classIRI>
<classLabel>methionine catabolic process to 3-methylthiopropanoate</classLabel>
<deletedAxiom>&apos;methionine catabolic process to 3-methylthiopropanoate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_49016) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32644)</deletedAxiom>
<deletedAxiom>&apos;methionine catabolic process to 3-methylthiopropanoate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_49016</deletedAxiom>
<newAxiom>&apos;methionine catabolic process to 3-methylthiopropanoate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_49016</newAxiom>
<newAxiom>&apos;methionine catabolic process to 3-methylthiopropanoate&apos; SubClassOf &apos;fatty acid biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;methionine catabolic process to 3-methylthiopropanoate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_49016) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32644)</newAxiom>
<newAxiom>&apos;methionine catabolic process to 3-methylthiopropanoate&apos; SubClassOf &apos;toxin biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;methionine catabolic process to 3-methylthiopropanoate&apos; SubClassOf &apos;sulfur compound biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000951</classIRI>
<classLabel>methionine catabolic process to 3-methylthiopropanol</classLabel>
<deletedAxiom>&apos;methionine catabolic process to 3-methylthiopropanol&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_49019</deletedAxiom>
<deletedAxiom>&apos;methionine catabolic process to 3-methylthiopropanol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_49019) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32644)</deletedAxiom>
<newAxiom>&apos;methionine catabolic process to 3-methylthiopropanol&apos; SubClassOf &apos;sulfur compound biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;methionine catabolic process to 3-methylthiopropanol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_49019) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32644)</newAxiom>
<newAxiom>&apos;methionine catabolic process to 3-methylthiopropanol&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_49019</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010122</classIRI>
<classLabel>arginine catabolic process to alanine via ornithine</classLabel>
<deletedAxiom>&apos;arginine catabolic process to alanine via ornithine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_32964) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_32439) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32695)</deletedAxiom>
<deletedAxiom>&apos;arginine catabolic process to alanine via ornithine&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_32439</deletedAxiom>
<newAxiom>&apos;arginine catabolic process to alanine via ornithine&apos; SubClassOf &apos;alanine metabolic process&apos;</newAxiom>
<newAxiom>&apos;arginine catabolic process to alanine via ornithine&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32439</newAxiom>
<newAxiom>&apos;arginine catabolic process to alanine via ornithine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_32964) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32439) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32695)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010123</classIRI>
<classLabel>acetate catabolic process to butyrate, ethanol, acetone and butanol</classLabel>
<deletedAxiom>&apos;acetate catabolic process to butyrate, ethanol, acetone and butanol&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16236</deletedAxiom>
<deletedAxiom>&apos;acetate catabolic process to butyrate, ethanol, acetone and butanol&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15347</deletedAxiom>
<deletedAxiom>&apos;acetate catabolic process to butyrate, ethanol, acetone and butanol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15347) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16236) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17968) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_28885) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_30089)</deletedAxiom>
<deletedAxiom>&apos;acetate catabolic process to butyrate, ethanol, acetone and butanol&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_28885</deletedAxiom>
<deletedAxiom>&apos;acetate catabolic process to butyrate, ethanol, acetone and butanol&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17968</deletedAxiom>
<newAxiom>&apos;acetate catabolic process to butyrate, ethanol, acetone and butanol&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15347</newAxiom>
<newAxiom>&apos;acetate catabolic process to butyrate, ethanol, acetone and butanol&apos; SubClassOf &apos;1-butanol metabolic process&apos;</newAxiom>
<newAxiom>&apos;acetate catabolic process to butyrate, ethanol, acetone and butanol&apos; SubClassOf &apos;acetone metabolic process&apos;</newAxiom>
<newAxiom>&apos;acetate catabolic process to butyrate, ethanol, acetone and butanol&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17968</newAxiom>
<newAxiom>&apos;acetate catabolic process to butyrate, ethanol, acetone and butanol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15347) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16236) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17968) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_28885) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_30089)</newAxiom>
<newAxiom>&apos;acetate catabolic process to butyrate, ethanol, acetone and butanol&apos; SubClassOf &apos;ethanol metabolic process&apos;</newAxiom>
<newAxiom>&apos;acetate catabolic process to butyrate, ethanol, acetone and butanol&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16236</newAxiom>
<newAxiom>&apos;acetate catabolic process to butyrate, ethanol, acetone and butanol&apos; SubClassOf &apos;butyrate metabolic process&apos;</newAxiom>
<newAxiom>&apos;acetate catabolic process to butyrate, ethanol, acetone and butanol&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_28885</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010121</classIRI>
<classLabel>arginine catabolic process to proline via ornithine</classLabel>
<deletedAxiom>&apos;arginine catabolic process to proline via ornithine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_32964) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_32871) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32695)</deletedAxiom>
<newAxiom>&apos;arginine catabolic process to proline via ornithine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_32964) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32871) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32695)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010133</classIRI>
<classLabel>proline catabolic process to glutamate</classLabel>
<deletedAxiom>&apos;proline catabolic process to glutamate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_29987</deletedAxiom>
<deletedAxiom>&apos;proline catabolic process to glutamate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_29987) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32871)</deletedAxiom>
<newAxiom>&apos;proline catabolic process to glutamate&apos; SubClassOf &apos;glutamate metabolic process&apos;</newAxiom>
<newAxiom>&apos;proline catabolic process to glutamate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_29987</newAxiom>
<newAxiom>&apos;proline catabolic process to glutamate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_29987) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32871)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010144</classIRI>
<classLabel>pyridoxal phosphate biosynthetic process from pyridoxamine</classLabel>
<deletedAxiom>&apos;pyridoxal phosphate biosynthetic process from pyridoxamine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_16410</deletedAxiom>
<deletedAxiom>&apos;pyridoxal phosphate biosynthetic process from pyridoxamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_16410) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_18405)</deletedAxiom>
<newAxiom>&apos;pyridoxal phosphate biosynthetic process from pyridoxamine&apos; SubClassOf &apos;pyridoxamine metabolic process&apos;</newAxiom>
<newAxiom>&apos;pyridoxal phosphate biosynthetic process from pyridoxamine&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16410</newAxiom>
<newAxiom>&apos;pyridoxal phosphate biosynthetic process from pyridoxamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_18405) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16410)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009051</classIRI>
<classLabel>pentose-phosphate shunt, oxidative branch</classLabel>
<deletedAxiom>&apos;pentose-phosphate shunt, oxidative branch&apos; SubClassOf &apos;has part&apos; some &apos;NADPH regeneration&apos;</deletedAxiom>
<deletedAxiom>&apos;pentose-phosphate shunt, oxidative branch&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has part&apos; some &apos;gluconolactonase activity&apos;) and (&apos;has part&apos; some &apos;NADPH regeneration&apos;) and (&apos;starts with&apos; some &apos;glucose-6-phosphate dehydrogenase activity&apos;) and (&apos;ends with&apos; some &apos;phosphogluconate dehydrogenase (decarboxylating) activity&apos;) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_14314)</deletedAxiom>
<newAxiom>&apos;pentose-phosphate shunt, oxidative branch&apos; SubClassOf &apos;NADPH regeneration&apos;</newAxiom>
<newAxiom>&apos;pentose-phosphate shunt, oxidative branch&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has part&apos; some &apos;gluconolactonase activity&apos;) and (&apos;starts with&apos; some &apos;glucose-6-phosphate dehydrogenase activity&apos;) and (&apos;ends with&apos; some &apos;phosphogluconate dehydrogenase (decarboxylating) activity&apos;) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18009) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16474) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_14314)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990181</classIRI>
<classLabel>acetyl-CoA biosynthetic process from pantothenate</classLabel>
<deletedAxiom>&apos;acetyl-CoA biosynthetic process from pantothenate&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_16454</deletedAxiom>
<deletedAxiom>&apos;acetyl-CoA biosynthetic process from pantothenate&apos; SubClassOf &apos;cellular modified amino acid metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;acetyl-CoA biosynthetic process from pantothenate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_16454) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15351)</deletedAxiom>
<newAxiom>&apos;acetyl-CoA biosynthetic process from pantothenate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15351) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16454)</newAxiom>
<newAxiom>&apos;acetyl-CoA biosynthetic process from pantothenate&apos; SubClassOf &apos;pantothenate metabolic process&apos;</newAxiom>
<newAxiom>&apos;acetyl-CoA biosynthetic process from pantothenate&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16454</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901410</classIRI>
<classLabel>regulation of tetrapyrrole biosynthetic process from glutamate</classLabel>
<newAxiom>&apos;regulation of tetrapyrrole biosynthetic process from glutamate&apos; SubClassOf &apos;regulation of glutamate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901411</classIRI>
<classLabel>negative regulation of tetrapyrrole biosynthetic process from glutamate</classLabel>
<newAxiom>&apos;negative regulation of tetrapyrrole biosynthetic process from glutamate&apos; SubClassOf &apos;negative regulation of glutamate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901412</classIRI>
<classLabel>positive regulation of tetrapyrrole biosynthetic process from glutamate</classLabel>
<newAxiom>&apos;positive regulation of tetrapyrrole biosynthetic process from glutamate&apos; SubClassOf &apos;positive regulation of glutamate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901413</classIRI>
<classLabel>regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA</classLabel>
<newAxiom>&apos;regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA&apos; SubClassOf &apos;regulation of cellular amide metabolic process&apos;</newAxiom>
<newAxiom>&apos;regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA&apos; SubClassOf &apos;regulation of coenzyme metabolic process&apos;</newAxiom>
<newAxiom>&apos;regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA&apos; SubClassOf &apos;regulation of sulfur metabolic process&apos;</newAxiom>
<newAxiom>&apos;regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA&apos; SubClassOf &apos;regulation of neurotransmitter levels&apos;</newAxiom>
<newAxiom>&apos;regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA&apos; SubClassOf &apos;regulation of purine nucleotide metabolic process&apos;</newAxiom>
<newAxiom>&apos;regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA&apos; SubClassOf &apos;regulation of cellular amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901414</classIRI>
<classLabel>negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA</classLabel>
<newAxiom>&apos;negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA&apos; SubClassOf &apos;negative regulation of coenzyme metabolic process&apos;</newAxiom>
<newAxiom>&apos;negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA&apos; SubClassOf &apos;negative regulation of purine nucleotide metabolic process&apos;</newAxiom>
<newAxiom>&apos;negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA&apos; SubClassOf &apos;negative regulation of cellular amide metabolic process&apos;</newAxiom>
<newAxiom>&apos;negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA&apos; SubClassOf &apos;negative regulation of cellular amino acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA&apos; SubClassOf &apos;negative regulation of sulfur metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901415</classIRI>
<classLabel>positive regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA</classLabel>
<newAxiom>&apos;positive regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA&apos; SubClassOf &apos;positive regulation of purine nucleotide metabolic process&apos;</newAxiom>
<newAxiom>&apos;positive regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA&apos; SubClassOf &apos;positive regulation of sulfur metabolic process&apos;</newAxiom>
<newAxiom>&apos;positive regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA&apos; SubClassOf &apos;positive regulation of cellular amide metabolic process&apos;</newAxiom>
<newAxiom>&apos;positive regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA&apos; SubClassOf &apos;positive regulation of cellular amino acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;positive regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA&apos; SubClassOf &apos;positive regulation of coenzyme metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043456</classIRI>
<classLabel>regulation of pentose-phosphate shunt</classLabel>
<newAxiom>&apos;regulation of pentose-phosphate shunt&apos; SubClassOf &apos;regulation of NADP metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018173</classIRI>
<classLabel>peptidyl-1-thioglycine biosynthetic process from peptidyl-glycine</classLabel>
<deletedAxiom>&apos;peptidyl-1-thioglycine biosynthetic process from peptidyl-glycine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_25921</deletedAxiom>
<deletedAxiom>&apos;peptidyl-1-thioglycine biosynthetic process from peptidyl-glycine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_25921) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_25909)</deletedAxiom>
<newAxiom>&apos;peptidyl-1-thioglycine biosynthetic process from peptidyl-glycine&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_25921</newAxiom>
<newAxiom>&apos;peptidyl-1-thioglycine biosynthetic process from peptidyl-glycine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_25909) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_25921)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905012</classIRI>
<classLabel>regulation of &apos;de novo&apos; NAD biosynthetic process from tryptophan</classLabel>
<deletedAxiom>&apos;regulation of &apos;de novo&apos; NAD biosynthetic process from tryptophan&apos; SubClassOf &apos;regulation of NAD metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of &apos;de novo&apos; NAD biosynthetic process from tryptophan&apos; SubClassOf &apos;regulation of coenzyme metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905013</classIRI>
<classLabel>negative regulation of &apos;de novo&apos; NAD biosynthetic process from tryptophan</classLabel>
<deletedAxiom>&apos;negative regulation of &apos;de novo&apos; NAD biosynthetic process from tryptophan&apos; SubClassOf &apos;negative regulation of NAD metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of &apos;de novo&apos; NAD biosynthetic process from tryptophan&apos; SubClassOf &apos;negative regulation of coenzyme metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905014</classIRI>
<classLabel>positive regulation of &apos;de novo&apos; NAD biosynthetic process from tryptophan</classLabel>
<deletedAxiom>&apos;positive regulation of &apos;de novo&apos; NAD biosynthetic process from tryptophan&apos; SubClassOf &apos;positive regulation of NAD metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of &apos;de novo&apos; NAD biosynthetic process from tryptophan&apos; SubClassOf &apos;positive regulation of coenzyme metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905570</classIRI>
<classLabel>positive regulation of ferrichrome biosynthetic process</classLabel>
<newAxiom>&apos;positive regulation of ferrichrome biosynthetic process&apos; SubClassOf &apos;positive regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905568</classIRI>
<classLabel>regulation of ferrichrome biosynthetic process</classLabel>
<newAxiom>&apos;regulation of ferrichrome biosynthetic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905569</classIRI>
<classLabel>negative regulation of ferrichrome biosynthetic process</classLabel>
<newAxiom>&apos;negative regulation of ferrichrome biosynthetic process&apos; SubClassOf &apos;negative regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030645</classIRI>
<classLabel>glucose catabolic process to butyrate</classLabel>
<deletedAxiom>&apos;glucose catabolic process to butyrate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17968) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17234)</deletedAxiom>
<newAxiom>&apos;glucose catabolic process to butyrate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17968) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17234)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900320</classIRI>
<classLabel>positive regulation of methane biosynthetic process from dimethylamine</classLabel>
<newAxiom>&apos;positive regulation of methane biosynthetic process from dimethylamine&apos; SubClassOf &apos;positive regulation of nitrogen compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900330</classIRI>
<classLabel>regulation of methane biosynthetic process from trimethylamine</classLabel>
<newAxiom>&apos;regulation of methane biosynthetic process from trimethylamine&apos; SubClassOf &apos;regulation of nitrogen compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900331</classIRI>
<classLabel>negative regulation of methane biosynthetic process from trimethylamine</classLabel>
<newAxiom>&apos;negative regulation of methane biosynthetic process from trimethylamine&apos; SubClassOf &apos;negative regulation of nitrogen compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900332</classIRI>
<classLabel>positive regulation of methane biosynthetic process from trimethylamine</classLabel>
<newAxiom>&apos;positive regulation of methane biosynthetic process from trimethylamine&apos; SubClassOf &apos;positive regulation of nitrogen compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900333</classIRI>
<classLabel>regulation of methane biosynthetic process from 3-(methylthio)propionic acid</classLabel>
<newAxiom>&apos;regulation of methane biosynthetic process from 3-(methylthio)propionic acid&apos; SubClassOf &apos;regulation of sulfur metabolic process&apos;</newAxiom>
<newAxiom>&apos;regulation of methane biosynthetic process from 3-(methylthio)propionic acid&apos; SubClassOf &apos;regulation of fatty acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;regulation of methane biosynthetic process from 3-(methylthio)propionic acid&apos; SubClassOf &apos;regulation of secondary metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900334</classIRI>
<classLabel>negative regulation of methane biosynthetic process from 3-(methylthio)propionic acid</classLabel>
<newAxiom>&apos;negative regulation of methane biosynthetic process from 3-(methylthio)propionic acid&apos; SubClassOf &apos;negative regulation of sulfur metabolic process&apos;</newAxiom>
<newAxiom>&apos;negative regulation of methane biosynthetic process from 3-(methylthio)propionic acid&apos; SubClassOf &apos;negative regulation of fatty acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900335</classIRI>
<classLabel>positive regulation of methane biosynthetic process from 3-(methylthio)propionic acid</classLabel>
<newAxiom>&apos;positive regulation of methane biosynthetic process from 3-(methylthio)propionic acid&apos; SubClassOf &apos;positive regulation of sulfur metabolic process&apos;</newAxiom>
<newAxiom>&apos;positive regulation of methane biosynthetic process from 3-(methylthio)propionic acid&apos; SubClassOf &apos;positive regulation of fatty acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900336</classIRI>
<classLabel>regulation of methane biosynthetic process from carbon monoxide</classLabel>
<newAxiom>&apos;regulation of methane biosynthetic process from carbon monoxide&apos; SubClassOf &apos;regulation of neurotransmitter levels&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900318</classIRI>
<classLabel>regulation of methane biosynthetic process from dimethylamine</classLabel>
<newAxiom>&apos;regulation of methane biosynthetic process from dimethylamine&apos; SubClassOf &apos;regulation of nitrogen compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900319</classIRI>
<classLabel>negative regulation of methane biosynthetic process from dimethylamine</classLabel>
<newAxiom>&apos;negative regulation of methane biosynthetic process from dimethylamine&apos; SubClassOf &apos;negative regulation of nitrogen compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900340</classIRI>
<classLabel>negative regulation of methane biosynthetic process from formic acid</classLabel>
<newAxiom>&apos;negative regulation of methane biosynthetic process from formic acid&apos; SubClassOf &apos;negative regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900341</classIRI>
<classLabel>positive regulation of methane biosynthetic process from formic acid</classLabel>
<newAxiom>&apos;positive regulation of methane biosynthetic process from formic acid&apos; SubClassOf &apos;positive regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900342</classIRI>
<classLabel>regulation of methane biosynthetic process from dimethyl sulfide</classLabel>
<newAxiom>&apos;regulation of methane biosynthetic process from dimethyl sulfide&apos; SubClassOf &apos;regulation of sulfur metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900343</classIRI>
<classLabel>negative regulation of methane biosynthetic process from dimethyl sulfide</classLabel>
<newAxiom>&apos;negative regulation of methane biosynthetic process from dimethyl sulfide&apos; SubClassOf &apos;negative regulation of sulfur metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900344</classIRI>
<classLabel>positive regulation of methane biosynthetic process from dimethyl sulfide</classLabel>
<newAxiom>&apos;positive regulation of methane biosynthetic process from dimethyl sulfide&apos; SubClassOf &apos;positive regulation of sulfur metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900345</classIRI>
<classLabel>regulation of methane biosynthetic process from methanethiol</classLabel>
<newAxiom>&apos;regulation of methane biosynthetic process from methanethiol&apos; SubClassOf &apos;regulation of sulfur metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900346</classIRI>
<classLabel>negative regulation of methane biosynthetic process from methanethiol</classLabel>
<newAxiom>&apos;negative regulation of methane biosynthetic process from methanethiol&apos; SubClassOf &apos;negative regulation of sulfur metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900347</classIRI>
<classLabel>positive regulation of methane biosynthetic process from methanethiol</classLabel>
<newAxiom>&apos;positive regulation of methane biosynthetic process from methanethiol&apos; SubClassOf &apos;positive regulation of sulfur metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900348</classIRI>
<classLabel>regulation of methane biosynthetic process from methylamine</classLabel>
<newAxiom>&apos;regulation of methane biosynthetic process from methylamine&apos; SubClassOf &apos;regulation of nitrogen compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900349</classIRI>
<classLabel>negative regulation of methane biosynthetic process from methylamine</classLabel>
<newAxiom>&apos;negative regulation of methane biosynthetic process from methylamine&apos; SubClassOf &apos;negative regulation of nitrogen compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900350</classIRI>
<classLabel>positive regulation of methane biosynthetic process from methylamine</classLabel>
<newAxiom>&apos;positive regulation of methane biosynthetic process from methylamine&apos; SubClassOf &apos;positive regulation of nitrogen compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019617</classIRI>
<classLabel>protocatechuate catabolic process, meta-cleavage</classLabel>
<deletedAxiom>&apos;protocatechuate catabolic process, meta-cleavage&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16452</deletedAxiom>
<deletedAxiom>&apos;protocatechuate catabolic process, meta-cleavage&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15361</deletedAxiom>
<deletedAxiom>&apos;protocatechuate catabolic process, meta-cleavage&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15361) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16452) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_36241)</deletedAxiom>
<newAxiom>&apos;protocatechuate catabolic process, meta-cleavage&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15361) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16452) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_36241)</newAxiom>
<newAxiom>&apos;protocatechuate catabolic process, meta-cleavage&apos; SubClassOf &apos;pyruvate metabolic process&apos;</newAxiom>
<newAxiom>&apos;protocatechuate catabolic process, meta-cleavage&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15361</newAxiom>
<newAxiom>&apos;protocatechuate catabolic process, meta-cleavage&apos; SubClassOf &apos;oxaloacetate metabolic process&apos;</newAxiom>
<newAxiom>&apos;protocatechuate catabolic process, meta-cleavage&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16452</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019618</classIRI>
<classLabel>protocatechuate catabolic process, ortho-cleavage</classLabel>
<deletedAxiom>&apos;protocatechuate catabolic process, ortho-cleavage&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_37440</deletedAxiom>
<deletedAxiom>&apos;protocatechuate catabolic process, ortho-cleavage&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_37440) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_36241)</deletedAxiom>
<newAxiom>&apos;protocatechuate catabolic process, ortho-cleavage&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_37440</newAxiom>
<newAxiom>&apos;protocatechuate catabolic process, ortho-cleavage&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_37440) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_36241)</newAxiom>
<newAxiom>&apos;protocatechuate catabolic process, ortho-cleavage&apos; SubClassOf &apos;dicarboxylic acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019621</classIRI>
<classLabel>creatinine catabolic process to formate</classLabel>
<deletedAxiom>&apos;creatinine catabolic process to formate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15740) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16737)</deletedAxiom>
<deletedAxiom>&apos;creatinine catabolic process to formate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15740</deletedAxiom>
<newAxiom>&apos;creatinine catabolic process to formate&apos; SubClassOf &apos;formate metabolic process&apos;</newAxiom>
<newAxiom>&apos;creatinine catabolic process to formate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15740) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16737)</newAxiom>
<newAxiom>&apos;creatinine catabolic process to formate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15740</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019623</classIRI>
<classLabel>atrazine catabolic process to urea</classLabel>
<deletedAxiom>&apos;atrazine catabolic process to urea&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16199) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15930)</deletedAxiom>
<deletedAxiom>&apos;atrazine catabolic process to urea&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16199</deletedAxiom>
<newAxiom>&apos;atrazine catabolic process to urea&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16199</newAxiom>
<newAxiom>&apos;atrazine catabolic process to urea&apos; SubClassOf &apos;urea metabolic process&apos;</newAxiom>
<newAxiom>&apos;atrazine catabolic process to urea&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16199) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15930)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019624</classIRI>
<classLabel>atrazine catabolic process to isopropylamine</classLabel>
<deletedAxiom>&apos;atrazine catabolic process to isopropylamine&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15739</deletedAxiom>
<deletedAxiom>&apos;atrazine catabolic process to isopropylamine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15739) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15930)</deletedAxiom>
<newAxiom>&apos;atrazine catabolic process to isopropylamine&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15739</newAxiom>
<newAxiom>&apos;atrazine catabolic process to isopropylamine&apos; SubClassOf &apos;ammonium ion metabolic process&apos;</newAxiom>
<newAxiom>&apos;atrazine catabolic process to isopropylamine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15739) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15930)</newAxiom>
<newAxiom>&apos;atrazine catabolic process to isopropylamine&apos; SubClassOf &apos;primary amino compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019625</classIRI>
<classLabel>atrazine catabolic process to cyanuric acid</classLabel>
<deletedAxiom>&apos;atrazine catabolic process to cyanuric acid&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_38028) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15930)</deletedAxiom>
<deletedAxiom>&apos;atrazine catabolic process to cyanuric acid&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_38028</deletedAxiom>
<newAxiom>&apos;atrazine catabolic process to cyanuric acid&apos; SubClassOf &apos;cyanuric acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;atrazine catabolic process to cyanuric acid&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_38028) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15930)</newAxiom>
<newAxiom>&apos;atrazine catabolic process to cyanuric acid&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_38028</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019640</classIRI>
<classLabel>glucuronate catabolic process to xylulose 5-phosphate</classLabel>
<deletedAxiom>&apos;glucuronate catabolic process to xylulose 5-phosphate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_27354</deletedAxiom>
<deletedAxiom>&apos;glucuronate catabolic process to xylulose 5-phosphate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_27354) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_24297)</deletedAxiom>
<newAxiom>&apos;glucuronate catabolic process to xylulose 5-phosphate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_27354) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_24297)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019651</classIRI>
<classLabel>citrate catabolic process to diacetyl</classLabel>
<deletedAxiom>&apos;citrate catabolic process to diacetyl&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16583</deletedAxiom>
<deletedAxiom>&apos;citrate catabolic process to diacetyl&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16583) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16947)</deletedAxiom>
<newAxiom>&apos;citrate catabolic process to diacetyl&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16583) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16947)</newAxiom>
<newAxiom>&apos;citrate catabolic process to diacetyl&apos; SubClassOf &apos;cellular ketone metabolic process&apos;</newAxiom>
<newAxiom>&apos;citrate catabolic process to diacetyl&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16583</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019656</classIRI>
<classLabel>glucose catabolic process to D-lactate and ethanol</classLabel>
<deletedAxiom>&apos;glucose catabolic process to D-lactate and ethanol&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16004</deletedAxiom>
<deletedAxiom>&apos;glucose catabolic process to D-lactate and ethanol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16004) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16236) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17234)</deletedAxiom>
<newAxiom>&apos;glucose catabolic process to D-lactate and ethanol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16004) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16236) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17234)</newAxiom>
<newAxiom>&apos;glucose catabolic process to D-lactate and ethanol&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16004</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019658</classIRI>
<classLabel>glucose fermentation to lactate and acetate</classLabel>
<deletedAxiom>&apos;glucose fermentation to lactate and acetate&apos; SubClassOf &apos;hexose catabolic process to acetate&apos;</deletedAxiom>
<deletedAxiom>&apos;glucose fermentation to lactate and acetate&apos; SubClassOf &apos;glucose catabolic process to lactate&apos;</deletedAxiom>
<newAxiom>&apos;glucose fermentation to lactate and acetate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_30089</newAxiom>
<newAxiom>&apos;glucose fermentation to lactate and acetate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_24996</newAxiom>
<newAxiom>&apos;glucose fermentation to lactate and acetate&apos; SubClassOf &apos;glucose catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019659</classIRI>
<classLabel>glucose catabolic process to lactate</classLabel>
<deletedAxiom>&apos;glucose catabolic process to lactate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_24996</deletedAxiom>
<deletedAxiom>&apos;glucose catabolic process to lactate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_24996) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17234)</deletedAxiom>
<newAxiom>&apos;glucose catabolic process to lactate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_24996) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17234)</newAxiom>
<newAxiom>&apos;glucose catabolic process to lactate&apos; SubClassOf &apos;lactate metabolic process&apos;</newAxiom>
<newAxiom>&apos;glucose catabolic process to lactate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_24996</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019660</classIRI>
<classLabel>glycolytic fermentation</classLabel>
<newAxiom>&apos;glycolytic fermentation&apos; SubClassOf &apos;ATP metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019661</classIRI>
<classLabel>glucose catabolic process to lactate via pyruvate</classLabel>
<deletedAxiom>&apos;glucose catabolic process to lactate via pyruvate&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17234</deletedAxiom>
<deletedAxiom>&apos;glucose catabolic process to lactate via pyruvate&apos; EquivalentTo &apos;glucose catabolic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_15361) and (&apos;starts with&apos; some &apos;canonical glycolysis&apos;) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17234) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_24996)</deletedAxiom>
<newAxiom>&apos;glucose catabolic process to lactate via pyruvate&apos; EquivalentTo &apos;glucose catabolic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_15361) and (&apos;starts with&apos; some &apos;canonical glycolysis&apos;) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_24996) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17234)</newAxiom>
<newAxiom>&apos;glucose catabolic process to lactate via pyruvate&apos; SubClassOf &apos;NADH metabolic process&apos;</newAxiom>
<newAxiom>&apos;glucose catabolic process to lactate via pyruvate&apos; SubClassOf &apos;NAD metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019674</classIRI>
<classLabel>NAD metabolic process</classLabel>
<deletedAxiom>&apos;NAD metabolic process&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has primary input or output&apos; some http://purl.obolibrary.org/obo/CHEBI_13389)</deletedAxiom>
<deletedAxiom>&apos;NAD metabolic process&apos; SubClassOf &apos;has primary input or output&apos; some http://purl.obolibrary.org/obo/CHEBI_13389</deletedAxiom>
<deletedAxiom>&apos;NAD metabolic process&apos; SubClassOf &apos;nicotinamide nucleotide metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;NAD metabolic process&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has participant&apos; some http://purl.obolibrary.org/obo/CHEBI_15846)</newAxiom>
<newAxiom>&apos;NAD metabolic process&apos; SubClassOf &apos;has participant&apos; some http://purl.obolibrary.org/obo/CHEBI_15846</newAxiom>
<newAxiom>&apos;NAD metabolic process&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019677</classIRI>
<classLabel>NAD catabolic process</classLabel>
<deletedAxiom>&apos;NAD catabolic process&apos; SubClassOf &apos;NAD metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;NAD catabolic process&apos; SubClassOf &apos;nicotinamide nucleotide metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019687</classIRI>
<classLabel>pyruvate biosynthetic process from acetate</classLabel>
<deletedAxiom>&apos;pyruvate biosynthetic process from acetate&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_30089</deletedAxiom>
<deletedAxiom>&apos;pyruvate biosynthetic process from acetate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_30089) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15361)</deletedAxiom>
<newAxiom>&apos;pyruvate biosynthetic process from acetate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15361) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_30089)</newAxiom>
<newAxiom>&apos;pyruvate biosynthetic process from acetate&apos; SubClassOf &apos;acetate metabolic process&apos;</newAxiom>
<newAxiom>&apos;pyruvate biosynthetic process from acetate&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_30089</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019697</classIRI>
<classLabel>L-xylitol catabolic process to xylulose 5-phosphate</classLabel>
<deletedAxiom>&apos;L-xylitol catabolic process to xylulose 5-phosphate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_27354) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17151)</deletedAxiom>
<deletedAxiom>&apos;L-xylitol catabolic process to xylulose 5-phosphate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_27354</deletedAxiom>
<newAxiom>&apos;L-xylitol catabolic process to xylulose 5-phosphate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_27354) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17151)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044581</classIRI>
<classLabel>butyryl-CoA catabolic process to butyrate</classLabel>
<deletedAxiom>&apos;butyryl-CoA catabolic process to butyrate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17968</deletedAxiom>
<deletedAxiom>&apos;butyryl-CoA catabolic process to butyrate&apos; EquivalentTo &apos;butyryl-CoA catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17968)</deletedAxiom>
<newAxiom>&apos;butyryl-CoA catabolic process to butyrate&apos; EquivalentTo &apos;butyryl-CoA catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17968)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044579</classIRI>
<classLabel>butyryl-CoA biosynthetic process from acetyl-CoA</classLabel>
<deletedAxiom>&apos;butyryl-CoA biosynthetic process from acetyl-CoA&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15351) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15517)</deletedAxiom>
<deletedAxiom>&apos;butyryl-CoA biosynthetic process from acetyl-CoA&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15351</deletedAxiom>
<newAxiom>&apos;butyryl-CoA biosynthetic process from acetyl-CoA&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15517) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15351)</newAxiom>
<newAxiom>&apos;butyryl-CoA biosynthetic process from acetyl-CoA&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15351</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044576</classIRI>
<classLabel>pentose catabolic process to ethanol</classLabel>
<deletedAxiom>&apos;pentose catabolic process to ethanol&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16236</deletedAxiom>
<deletedAxiom>&apos;pentose catabolic process to ethanol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16236) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_25901)</deletedAxiom>
<newAxiom>&apos;pentose catabolic process to ethanol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16236) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_25901)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044577</classIRI>
<classLabel>xylose catabolic process to ethanol</classLabel>
<deletedAxiom>&apos;xylose catabolic process to ethanol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16236) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15936)</deletedAxiom>
<newAxiom>&apos;xylose catabolic process to ethanol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16236) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15936)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019508</classIRI>
<classLabel>2,5-dihydroxypyridine catabolic process to fumarate</classLabel>
<deletedAxiom>&apos;2,5-dihydroxypyridine catabolic process to fumarate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_29806</deletedAxiom>
<deletedAxiom>&apos;2,5-dihydroxypyridine catabolic process to fumarate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_29806) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16364)</deletedAxiom>
<newAxiom>&apos;2,5-dihydroxypyridine catabolic process to fumarate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_29806</newAxiom>
<newAxiom>&apos;2,5-dihydroxypyridine catabolic process to fumarate&apos; SubClassOf &apos;fumarate metabolic process&apos;</newAxiom>
<newAxiom>&apos;2,5-dihydroxypyridine catabolic process to fumarate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_29806) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16364)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019517</classIRI>
<classLabel>L-threonine catabolic process to D-lactate</classLabel>
<deletedAxiom>&apos;L-threonine catabolic process to D-lactate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16004) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16857)</deletedAxiom>
<deletedAxiom>&apos;L-threonine catabolic process to D-lactate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16004</deletedAxiom>
<newAxiom>&apos;L-threonine catabolic process to D-lactate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16004</newAxiom>
<newAxiom>&apos;L-threonine catabolic process to D-lactate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16004) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16857)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019518</classIRI>
<classLabel>L-threonine catabolic process to glycine</classLabel>
<deletedAxiom>&apos;L-threonine catabolic process to glycine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_32508) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16857)</deletedAxiom>
<deletedAxiom>&apos;L-threonine catabolic process to glycine&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_32508</deletedAxiom>
<newAxiom>&apos;L-threonine catabolic process to glycine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32508) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16857)</newAxiom>
<newAxiom>&apos;L-threonine catabolic process to glycine&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32508</newAxiom>
<newAxiom>&apos;L-threonine catabolic process to glycine&apos; SubClassOf &apos;glycine metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019528</classIRI>
<classLabel>D-arabitol catabolic process to xylulose 5-phosphate</classLabel>
<deletedAxiom>&apos;D-arabitol catabolic process to xylulose 5-phosphate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_27354) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18333)</deletedAxiom>
<deletedAxiom>&apos;D-arabitol catabolic process to xylulose 5-phosphate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_27354</deletedAxiom>
<newAxiom>&apos;D-arabitol catabolic process to xylulose 5-phosphate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_27354) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18333)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019539</classIRI>
<classLabel>siderophore biosynthetic process from hydroxamic acid</classLabel>
<deletedAxiom>&apos;siderophore biosynthetic process from hydroxamic acid&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_24650) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/GOCHE_26672)</deletedAxiom>
<deletedAxiom>&apos;siderophore biosynthetic process from hydroxamic acid&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_24650</deletedAxiom>
<newAxiom>&apos;siderophore biosynthetic process from hydroxamic acid&apos; SubClassOf &apos;oxoacid metabolic process&apos;</newAxiom>
<newAxiom>&apos;siderophore biosynthetic process from hydroxamic acid&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/GOCHE_26672) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_24650)</newAxiom>
<newAxiom>&apos;siderophore biosynthetic process from hydroxamic acid&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_24650</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019540</classIRI>
<classLabel>siderophore biosynthetic process from catechol</classLabel>
<deletedAxiom>&apos;siderophore biosynthetic process from catechol&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18135</deletedAxiom>
<deletedAxiom>&apos;siderophore biosynthetic process from catechol&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18135) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/GOCHE_26672)</deletedAxiom>
<newAxiom>&apos;siderophore biosynthetic process from catechol&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/GOCHE_26672) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18135)</newAxiom>
<newAxiom>&apos;siderophore biosynthetic process from catechol&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18135</newAxiom>
<newAxiom>&apos;siderophore biosynthetic process from catechol&apos; SubClassOf &apos;catechol-containing compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019544</classIRI>
<classLabel>arginine catabolic process to glutamate</classLabel>
<deletedAxiom>&apos;arginine catabolic process to glutamate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_29987</deletedAxiom>
<deletedAxiom>&apos;arginine catabolic process to glutamate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_29987) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32695)</deletedAxiom>
<newAxiom>&apos;arginine catabolic process to glutamate&apos; SubClassOf &apos;glutamate metabolic process&apos;</newAxiom>
<newAxiom>&apos;arginine catabolic process to glutamate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_29987) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32695)</newAxiom>
<newAxiom>&apos;arginine catabolic process to glutamate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_29987</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019545</classIRI>
<classLabel>arginine catabolic process to succinate</classLabel>
<deletedAxiom>&apos;arginine catabolic process to succinate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_30031</deletedAxiom>
<deletedAxiom>&apos;arginine catabolic process to succinate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_30031) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32695)</deletedAxiom>
<newAxiom>&apos;arginine catabolic process to succinate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_30031</newAxiom>
<newAxiom>&apos;arginine catabolic process to succinate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_30031) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32695)</newAxiom>
<newAxiom>&apos;arginine catabolic process to succinate&apos; SubClassOf &apos;succinate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019547</classIRI>
<classLabel>arginine catabolic process to ornithine</classLabel>
<deletedAxiom>&apos;arginine catabolic process to ornithine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_32964) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32695)</deletedAxiom>
<deletedAxiom>&apos;arginine catabolic process to ornithine&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_32964</deletedAxiom>
<newAxiom>&apos;arginine catabolic process to ornithine&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32964</newAxiom>
<newAxiom>&apos;arginine catabolic process to ornithine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32964) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32695)</newAxiom>
<newAxiom>&apos;arginine catabolic process to ornithine&apos; SubClassOf &apos;ornithine metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019548</classIRI>
<classLabel>arginine catabolic process to spermine</classLabel>
<deletedAxiom>&apos;arginine catabolic process to spermine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15746) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32695)</deletedAxiom>
<deletedAxiom>&apos;arginine catabolic process to spermine&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15746</deletedAxiom>
<newAxiom>&apos;arginine catabolic process to spermine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15746) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32695)</newAxiom>
<newAxiom>&apos;arginine catabolic process to spermine&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15746</newAxiom>
<newAxiom>&apos;arginine catabolic process to spermine&apos; SubClassOf &apos;spermine metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019549</classIRI>
<classLabel>glutamate catabolic process to succinate via succinate semialdehyde</classLabel>
<deletedAxiom>&apos;glutamate catabolic process to succinate via succinate semialdehyde&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_16265) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_30031) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987)</deletedAxiom>
<newAxiom>&apos;glutamate catabolic process to succinate via succinate semialdehyde&apos; SubClassOf &apos;succinate metabolic process&apos;</newAxiom>
<newAxiom>&apos;glutamate catabolic process to succinate via succinate semialdehyde&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_30031</newAxiom>
<newAxiom>&apos;glutamate catabolic process to succinate via succinate semialdehyde&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_16265) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_30031) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019550</classIRI>
<classLabel>glutamate catabolic process to aspartate</classLabel>
<deletedAxiom>&apos;glutamate catabolic process to aspartate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_29995) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987)</deletedAxiom>
<deletedAxiom>&apos;glutamate catabolic process to aspartate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_29995</deletedAxiom>
<newAxiom>&apos;glutamate catabolic process to aspartate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_29995</newAxiom>
<newAxiom>&apos;glutamate catabolic process to aspartate&apos; SubClassOf &apos;aspartate metabolic process&apos;</newAxiom>
<newAxiom>&apos;glutamate catabolic process to aspartate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_29995) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019551</classIRI>
<classLabel>glutamate catabolic process to 2-oxoglutarate</classLabel>
<deletedAxiom>&apos;glutamate catabolic process to 2-oxoglutarate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16810</deletedAxiom>
<deletedAxiom>&apos;glutamate catabolic process to 2-oxoglutarate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16810) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987)</deletedAxiom>
<newAxiom>&apos;glutamate catabolic process to 2-oxoglutarate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16810</newAxiom>
<newAxiom>&apos;glutamate catabolic process to 2-oxoglutarate&apos; SubClassOf &apos;2-oxoglutarate metabolic process&apos;</newAxiom>
<newAxiom>&apos;glutamate catabolic process to 2-oxoglutarate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16810) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019554</classIRI>
<classLabel>glutamate catabolic process to oxaloacetate</classLabel>
<deletedAxiom>&apos;glutamate catabolic process to oxaloacetate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16452) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987)</deletedAxiom>
<deletedAxiom>&apos;glutamate catabolic process to oxaloacetate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16452</deletedAxiom>
<newAxiom>&apos;glutamate catabolic process to oxaloacetate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16452</newAxiom>
<newAxiom>&apos;glutamate catabolic process to oxaloacetate&apos; SubClassOf &apos;oxaloacetate metabolic process&apos;</newAxiom>
<newAxiom>&apos;glutamate catabolic process to oxaloacetate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16452) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019555</classIRI>
<classLabel>glutamate catabolic process to ornithine</classLabel>
<deletedAxiom>&apos;glutamate catabolic process to ornithine&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_32964</deletedAxiom>
<deletedAxiom>&apos;glutamate catabolic process to ornithine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_32964) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987)</deletedAxiom>
<newAxiom>&apos;glutamate catabolic process to ornithine&apos; SubClassOf &apos;ornithine metabolic process&apos;</newAxiom>
<newAxiom>&apos;glutamate catabolic process to ornithine&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32964</newAxiom>
<newAxiom>&apos;glutamate catabolic process to ornithine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32964) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019556</classIRI>
<classLabel>histidine catabolic process to glutamate and formamide</classLabel>
<deletedAxiom>&apos;histidine catabolic process to glutamate and formamide&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_29987</deletedAxiom>
<deletedAxiom>&apos;histidine catabolic process to glutamate and formamide&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16397) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_29987) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32529)</deletedAxiom>
<deletedAxiom>&apos;histidine catabolic process to glutamate and formamide&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16397</deletedAxiom>
<newAxiom>&apos;histidine catabolic process to glutamate and formamide&apos; SubClassOf &apos;glutamate metabolic process&apos;</newAxiom>
<newAxiom>&apos;histidine catabolic process to glutamate and formamide&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16397</newAxiom>
<newAxiom>&apos;histidine catabolic process to glutamate and formamide&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16397) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_29987) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32529)</newAxiom>
<newAxiom>&apos;histidine catabolic process to glutamate and formamide&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_29987</newAxiom>
<newAxiom>&apos;histidine catabolic process to glutamate and formamide&apos; SubClassOf &apos;formamide metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019557</classIRI>
<classLabel>histidine catabolic process to glutamate and formate</classLabel>
<deletedAxiom>&apos;histidine catabolic process to glutamate and formate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15740</deletedAxiom>
<deletedAxiom>&apos;histidine catabolic process to glutamate and formate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_29987</deletedAxiom>
<deletedAxiom>&apos;histidine catabolic process to glutamate and formate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15740) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_29987) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32529)</deletedAxiom>
<newAxiom>&apos;histidine catabolic process to glutamate and formate&apos; SubClassOf &apos;formate metabolic process&apos;</newAxiom>
<newAxiom>&apos;histidine catabolic process to glutamate and formate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15740</newAxiom>
<newAxiom>&apos;histidine catabolic process to glutamate and formate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_29987</newAxiom>
<newAxiom>&apos;histidine catabolic process to glutamate and formate&apos; SubClassOf &apos;glutamate metabolic process&apos;</newAxiom>
<newAxiom>&apos;histidine catabolic process to glutamate and formate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15740) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_29987) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32529)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019558</classIRI>
<classLabel>histidine catabolic process to 2-oxoglutarate</classLabel>
<deletedAxiom>&apos;histidine catabolic process to 2-oxoglutarate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16810) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32529)</deletedAxiom>
<deletedAxiom>&apos;histidine catabolic process to 2-oxoglutarate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16810</deletedAxiom>
<newAxiom>&apos;histidine catabolic process to 2-oxoglutarate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16810) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32529)</newAxiom>
<newAxiom>&apos;histidine catabolic process to 2-oxoglutarate&apos; SubClassOf &apos;2-oxoglutarate metabolic process&apos;</newAxiom>
<newAxiom>&apos;histidine catabolic process to 2-oxoglutarate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16810</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019560</classIRI>
<classLabel>histidine catabolic process to hydantoin-5-propionate</classLabel>
<deletedAxiom>&apos;histidine catabolic process to hydantoin-5-propionate&apos; EquivalentTo &apos;histidine catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_28297)</deletedAxiom>
<deletedAxiom>&apos;histidine catabolic process to hydantoin-5-propionate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_28297</deletedAxiom>
<newAxiom>&apos;histidine catabolic process to hydantoin-5-propionate&apos; SubClassOf &apos;monocarboxylic acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;histidine catabolic process to hydantoin-5-propionate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_28297</newAxiom>
<newAxiom>&apos;histidine catabolic process to hydantoin-5-propionate&apos; EquivalentTo &apos;histidine catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_28297)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019569</classIRI>
<classLabel>L-arabinose catabolic process to xylulose 5-phosphate</classLabel>
<deletedAxiom>&apos;L-arabinose catabolic process to xylulose 5-phosphate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_27354</deletedAxiom>
<deletedAxiom>&apos;L-arabinose catabolic process to xylulose 5-phosphate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_27354) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_30849)</deletedAxiom>
<newAxiom>&apos;L-arabinose catabolic process to xylulose 5-phosphate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_27354) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_30849)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019570</classIRI>
<classLabel>L-arabinose catabolic process to 2-oxoglutarate</classLabel>
<deletedAxiom>&apos;L-arabinose catabolic process to 2-oxoglutarate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16810) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_30849)</deletedAxiom>
<deletedAxiom>&apos;L-arabinose catabolic process to 2-oxoglutarate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16810</deletedAxiom>
<newAxiom>&apos;L-arabinose catabolic process to 2-oxoglutarate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16810</newAxiom>
<newAxiom>&apos;L-arabinose catabolic process to 2-oxoglutarate&apos; SubClassOf &apos;2-oxoglutarate metabolic process&apos;</newAxiom>
<newAxiom>&apos;L-arabinose catabolic process to 2-oxoglutarate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16810) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_30849)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019573</classIRI>
<classLabel>D-arabinose catabolic process to xylulose 5-phosphate</classLabel>
<deletedAxiom>&apos;D-arabinose catabolic process to xylulose 5-phosphate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_27354) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17108)</deletedAxiom>
<deletedAxiom>&apos;D-arabinose catabolic process to xylulose 5-phosphate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_27354</deletedAxiom>
<newAxiom>&apos;D-arabinose catabolic process to xylulose 5-phosphate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_27354) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17108)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019574</classIRI>
<classLabel>sucrose catabolic process via 3&apos;-ketosucrose</classLabel>
<deletedAxiom>&apos;sucrose catabolic process via 3&apos;-ketosucrose&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has part&apos; some &apos;fructokinase activity&apos;) and (&apos;has part&apos; some &apos;3-ketoglucose-reductase activity&apos;) and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_17429) and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_28757) and (&apos;starts with&apos; some &apos;glucoside 3-dehydrogenase activity&apos;) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17234) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_78697) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17992)</deletedAxiom>
<deletedAxiom>&apos;sucrose catabolic process via 3&apos;-ketosucrose&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17234</deletedAxiom>
<deletedAxiom>&apos;sucrose catabolic process via 3&apos;-ketosucrose&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_78697</deletedAxiom>
<newAxiom>&apos;sucrose catabolic process via 3&apos;-ketosucrose&apos; SubClassOf &apos;phosphate-containing compound metabolic process&apos;</newAxiom>
<newAxiom>&apos;sucrose catabolic process via 3&apos;-ketosucrose&apos; SubClassOf &apos;organophosphate metabolic process&apos;</newAxiom>
<newAxiom>&apos;sucrose catabolic process via 3&apos;-ketosucrose&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_78697</newAxiom>
<newAxiom>&apos;sucrose catabolic process via 3&apos;-ketosucrose&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17234</newAxiom>
<newAxiom>&apos;sucrose catabolic process via 3&apos;-ketosucrose&apos; SubClassOf &apos;carbohydrate derivative metabolic process&apos;</newAxiom>
<newAxiom>&apos;sucrose catabolic process via 3&apos;-ketosucrose&apos; SubClassOf &apos;glucose metabolic process&apos;</newAxiom>
<newAxiom>&apos;sucrose catabolic process via 3&apos;-ketosucrose&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has part&apos; some &apos;fructokinase activity&apos;) and (&apos;has part&apos; some &apos;3-ketoglucose-reductase activity&apos;) and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_17429) and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_28757) and (&apos;starts with&apos; some &apos;glucoside 3-dehydrogenase activity&apos;) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17234) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_78697) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17992)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019589</classIRI>
<classLabel>anaerobic glycerol catabolic process to propane-1,3-diol</classLabel>
<deletedAxiom>&apos;anaerobic glycerol catabolic process to propane-1,3-diol&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16109</deletedAxiom>
<deletedAxiom>&apos;anaerobic glycerol catabolic process to propane-1,3-diol&apos; EquivalentTo &apos;anaerobic glycerol catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16109)</deletedAxiom>
<newAxiom>&apos;anaerobic glycerol catabolic process to propane-1,3-diol&apos; EquivalentTo &apos;anaerobic glycerol catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16109)</newAxiom>
<newAxiom>&apos;anaerobic glycerol catabolic process to propane-1,3-diol&apos; SubClassOf &apos;propanediol metabolic process&apos;</newAxiom>
<newAxiom>&apos;anaerobic glycerol catabolic process to propane-1,3-diol&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16109</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019597</classIRI>
<classLabel>(R)-mandelate catabolic process to benzoate</classLabel>
<deletedAxiom>&apos;(R)-mandelate catabolic process to benzoate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32382) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16150)</deletedAxiom>
<deletedAxiom>&apos;(R)-mandelate catabolic process to benzoate&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32382</deletedAxiom>
<newAxiom>&apos;(R)-mandelate catabolic process to benzoate&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32382</newAxiom>
<newAxiom>&apos;(R)-mandelate catabolic process to benzoate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16150) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32382)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019598</classIRI>
<classLabel>(R)-mandelate catabolic process to catechol</classLabel>
<deletedAxiom>&apos;(R)-mandelate catabolic process to catechol&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32382</deletedAxiom>
<deletedAxiom>&apos;(R)-mandelate catabolic process to catechol&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32382) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_18135)</deletedAxiom>
<newAxiom>&apos;(R)-mandelate catabolic process to catechol&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32382</newAxiom>
<newAxiom>&apos;(R)-mandelate catabolic process to catechol&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_18135) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32382)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019590</classIRI>
<classLabel>L-arabitol catabolic process to xylulose 5-phosphate</classLabel>
<deletedAxiom>&apos;L-arabitol catabolic process to xylulose 5-phosphate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_27354) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18403)</deletedAxiom>
<deletedAxiom>&apos;L-arabitol catabolic process to xylulose 5-phosphate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_27354</deletedAxiom>
<newAxiom>&apos;L-arabitol catabolic process to xylulose 5-phosphate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_27354) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18403)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019415</classIRI>
<classLabel>acetate biosynthetic process from carbon monoxide</classLabel>
<deletedAxiom>&apos;acetate biosynthetic process from carbon monoxide&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17245) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_30089)</deletedAxiom>
<deletedAxiom>&apos;acetate biosynthetic process from carbon monoxide&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17245</deletedAxiom>
<newAxiom>&apos;acetate biosynthetic process from carbon monoxide&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_30089) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17245)</newAxiom>
<newAxiom>&apos;acetate biosynthetic process from carbon monoxide&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17245</newAxiom>
<newAxiom>&apos;acetate biosynthetic process from carbon monoxide&apos; SubClassOf &apos;neurotransmitter metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019427</classIRI>
<classLabel>acetyl-CoA biosynthetic process from acetate</classLabel>
<deletedAxiom>&apos;acetyl-CoA biosynthetic process from acetate&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_30089</deletedAxiom>
<deletedAxiom>&apos;acetyl-CoA biosynthetic process from acetate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_30089) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15351)</deletedAxiom>
<newAxiom>&apos;acetyl-CoA biosynthetic process from acetate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15351) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_30089)</newAxiom>
<newAxiom>&apos;acetyl-CoA biosynthetic process from acetate&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_30089</newAxiom>
<newAxiom>&apos;acetyl-CoA biosynthetic process from acetate&apos; SubClassOf &apos;acetate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019431</classIRI>
<classLabel>acetyl-CoA biosynthetic process from ethanol</classLabel>
<deletedAxiom>&apos;acetyl-CoA biosynthetic process from ethanol&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_16236</deletedAxiom>
<deletedAxiom>&apos;acetyl-CoA biosynthetic process from ethanol&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_16236) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15351)</deletedAxiom>
<newAxiom>&apos;acetyl-CoA biosynthetic process from ethanol&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15351) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16236)</newAxiom>
<newAxiom>&apos;acetyl-CoA biosynthetic process from ethanol&apos; SubClassOf &apos;ethanol metabolic process&apos;</newAxiom>
<newAxiom>&apos;acetyl-CoA biosynthetic process from ethanol&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16236</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019440</classIRI>
<classLabel>tryptophan catabolic process to indole-3-acetate</classLabel>
<deletedAxiom>&apos;tryptophan catabolic process to indole-3-acetate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_30854</deletedAxiom>
<deletedAxiom>&apos;tryptophan catabolic process to indole-3-acetate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_30854) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_27897)</deletedAxiom>
<newAxiom>&apos;tryptophan catabolic process to indole-3-acetate&apos; SubClassOf &apos;indoleacetic acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;tryptophan catabolic process to indole-3-acetate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_30854) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_27897)</newAxiom>
<newAxiom>&apos;tryptophan catabolic process to indole-3-acetate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_30854</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019441</classIRI>
<classLabel>tryptophan catabolic process to kynurenine</classLabel>
<deletedAxiom>&apos;tryptophan catabolic process to kynurenine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_28683) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_27897)</deletedAxiom>
<deletedAxiom>&apos;tryptophan catabolic process to kynurenine&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_28683</deletedAxiom>
<newAxiom>&apos;tryptophan catabolic process to kynurenine&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_28683</newAxiom>
<newAxiom>&apos;tryptophan catabolic process to kynurenine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_28683) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_27897)</newAxiom>
<newAxiom>&apos;tryptophan catabolic process to kynurenine&apos; SubClassOf &apos;kynurenine metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019442</classIRI>
<classLabel>tryptophan catabolic process to acetyl-CoA</classLabel>
<deletedAxiom>&apos;tryptophan catabolic process to acetyl-CoA&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15351</deletedAxiom>
<deletedAxiom>&apos;tryptophan catabolic process to acetyl-CoA&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15351) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_27897)</deletedAxiom>
<newAxiom>&apos;tryptophan catabolic process to acetyl-CoA&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15351) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_27897)</newAxiom>
<newAxiom>&apos;tryptophan catabolic process to acetyl-CoA&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15351</newAxiom>
<newAxiom>&apos;tryptophan catabolic process to acetyl-CoA&apos; SubClassOf &apos;acetyl-CoA metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019444</classIRI>
<classLabel>tryptophan catabolic process to catechol</classLabel>
<deletedAxiom>&apos;tryptophan catabolic process to catechol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_18135) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_27897)</deletedAxiom>
<deletedAxiom>&apos;tryptophan catabolic process to catechol&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_18135</deletedAxiom>
<newAxiom>&apos;tryptophan catabolic process to catechol&apos; SubClassOf &apos;catechol-containing compound metabolic process&apos;</newAxiom>
<newAxiom>&apos;tryptophan catabolic process to catechol&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_18135</newAxiom>
<newAxiom>&apos;tryptophan catabolic process to catechol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_18135) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_27897)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019445</classIRI>
<classLabel>tyrosine catabolic process to fumarate</classLabel>
<deletedAxiom>&apos;tyrosine catabolic process to fumarate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_29806</deletedAxiom>
<deletedAxiom>&apos;tyrosine catabolic process to fumarate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_29806) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18186)</deletedAxiom>
<newAxiom>&apos;tyrosine catabolic process to fumarate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_29806</newAxiom>
<newAxiom>&apos;tyrosine catabolic process to fumarate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_29806) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18186)</newAxiom>
<newAxiom>&apos;tyrosine catabolic process to fumarate&apos; SubClassOf &apos;fumarate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019449</classIRI>
<classLabel>L-cysteine catabolic process to hypotaurine</classLabel>
<deletedAxiom>&apos;L-cysteine catabolic process to hypotaurine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16668) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32442)</deletedAxiom>
<deletedAxiom>&apos;L-cysteine catabolic process to hypotaurine&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16668</deletedAxiom>
<newAxiom>&apos;L-cysteine catabolic process to hypotaurine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16668) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32442)</newAxiom>
<newAxiom>&apos;L-cysteine catabolic process to hypotaurine&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16668</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019450</classIRI>
<classLabel>L-cysteine catabolic process to pyruvate</classLabel>
<deletedAxiom>&apos;L-cysteine catabolic process to pyruvate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15361</deletedAxiom>
<deletedAxiom>&apos;L-cysteine catabolic process to pyruvate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15361) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32442)</deletedAxiom>
<newAxiom>&apos;L-cysteine catabolic process to pyruvate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15361</newAxiom>
<newAxiom>&apos;L-cysteine catabolic process to pyruvate&apos; SubClassOf &apos;pyruvate metabolic process&apos;</newAxiom>
<newAxiom>&apos;L-cysteine catabolic process to pyruvate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15361) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32442)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019451</classIRI>
<classLabel>L-cysteine catabolic process to pyruvate, using cysteine dioxygenase</classLabel>
<deletedAxiom>&apos;L-cysteine catabolic process to pyruvate, using cysteine dioxygenase&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has participant&apos; some &apos;cysteine dioxygenase activity&apos;) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15361) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32442)</deletedAxiom>
<newAxiom>&apos;L-cysteine catabolic process to pyruvate, using cysteine dioxygenase&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has participant&apos; some &apos;cysteine dioxygenase activity&apos;) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15361) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32442)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019452</classIRI>
<classLabel>L-cysteine catabolic process to taurine</classLabel>
<deletedAxiom>&apos;L-cysteine catabolic process to taurine&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15891</deletedAxiom>
<deletedAxiom>&apos;L-cysteine catabolic process to taurine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15891) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32442)</deletedAxiom>
<newAxiom>&apos;L-cysteine catabolic process to taurine&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15891</newAxiom>
<newAxiom>&apos;L-cysteine catabolic process to taurine&apos; SubClassOf &apos;taurine metabolic process&apos;</newAxiom>
<newAxiom>&apos;L-cysteine catabolic process to taurine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15891) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32442)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019457</classIRI>
<classLabel>methionine catabolic process to succinyl-CoA</classLabel>
<deletedAxiom>&apos;methionine catabolic process to succinyl-CoA&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15380</deletedAxiom>
<deletedAxiom>&apos;methionine catabolic process to succinyl-CoA&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15380) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32644)</deletedAxiom>
<newAxiom>&apos;methionine catabolic process to succinyl-CoA&apos; SubClassOf &apos;succinyl-CoA metabolic process&apos;</newAxiom>
<newAxiom>&apos;methionine catabolic process to succinyl-CoA&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15380) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32644)</newAxiom>
<newAxiom>&apos;methionine catabolic process to succinyl-CoA&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15380</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019460</classIRI>
<classLabel>glutamine catabolic process to fumarate</classLabel>
<deletedAxiom>&apos;glutamine catabolic process to fumarate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_29806</deletedAxiom>
<deletedAxiom>&apos;glutamine catabolic process to fumarate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_29806) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987)</deletedAxiom>
<newAxiom>&apos;glutamine catabolic process to fumarate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_29806) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987)</newAxiom>
<newAxiom>&apos;glutamine catabolic process to fumarate&apos; SubClassOf &apos;fumarate metabolic process&apos;</newAxiom>
<newAxiom>&apos;glutamine catabolic process to fumarate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_29806</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019461</classIRI>
<classLabel>glutamine catabolic process to fumarate, using glutamate synthase (NADPH)</classLabel>
<deletedAxiom>&apos;glutamine catabolic process to fumarate, using glutamate synthase (NADPH)&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has participant&apos; some &apos;glutamate synthase (NADPH) activity&apos;) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_29806) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987)</deletedAxiom>
<deletedAxiom>&apos;glutamine catabolic process to fumarate, using glutamate synthase (NADPH)&apos; SubClassOf &apos;has participant&apos; some &apos;glutamate synthase (NADPH) activity&apos;</deletedAxiom>
<newAxiom>&apos;glutamine catabolic process to fumarate, using glutamate synthase (NADPH)&apos; SubClassOf &apos;has part&apos; some &apos;glutamate synthase (NADPH) activity&apos;</newAxiom>
<newAxiom>&apos;glutamine catabolic process to fumarate, using glutamate synthase (NADPH)&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has part&apos; some &apos;glutamate synthase (NADPH) activity&apos;) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_29806) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019462</classIRI>
<classLabel>glutamine catabolic process to fumarate, using glutaminase</classLabel>
<deletedAxiom>&apos;glutamine catabolic process to fumarate, using glutaminase&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has participant&apos; some &apos;glutaminase activity&apos;) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_29806) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987)</deletedAxiom>
<deletedAxiom>&apos;glutamine catabolic process to fumarate, using glutaminase&apos; SubClassOf &apos;has participant&apos; some &apos;glutaminase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;glutamine catabolic process to fumarate, using glutaminase&apos; SubClassOf &apos;glutamine catabolic process to fumarate&apos;</deletedAxiom>
<newAxiom>&apos;glutamine catabolic process to fumarate, using glutaminase&apos; SubClassOf &apos;has part&apos; some &apos;glutaminase activity&apos;</newAxiom>
<newAxiom>&apos;glutamine catabolic process to fumarate, using glutaminase&apos; SubClassOf &apos;glutamate catabolic process&apos;</newAxiom>
<newAxiom>&apos;glutamine catabolic process to fumarate, using glutaminase&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_29806</newAxiom>
<newAxiom>&apos;glutamine catabolic process to fumarate, using glutaminase&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has part&apos; some &apos;glutaminase activity&apos;) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_29806) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019463</classIRI>
<classLabel>glycine catabolic process to creatine</classLabel>
<deletedAxiom>&apos;glycine catabolic process to creatine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16919) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32508)</deletedAxiom>
<deletedAxiom>&apos;glycine catabolic process to creatine&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16919</deletedAxiom>
<deletedAxiom>&apos;glycine catabolic process to creatine&apos; SubClassOf &apos;cellular modified amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;glycine catabolic process to creatine&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16919</newAxiom>
<newAxiom>&apos;glycine catabolic process to creatine&apos; SubClassOf &apos;creatine metabolic process&apos;</newAxiom>
<newAxiom>&apos;glycine catabolic process to creatine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16919) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32508)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019474</classIRI>
<classLabel>L-lysine catabolic process to acetyl-CoA</classLabel>
<deletedAxiom>&apos;L-lysine catabolic process to acetyl-CoA&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15351) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32550)</deletedAxiom>
<deletedAxiom>&apos;L-lysine catabolic process to acetyl-CoA&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15351</deletedAxiom>
<newAxiom>&apos;L-lysine catabolic process to acetyl-CoA&apos; SubClassOf &apos;acetyl-CoA metabolic process&apos;</newAxiom>
<newAxiom>&apos;L-lysine catabolic process to acetyl-CoA&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15351) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32550)</newAxiom>
<newAxiom>&apos;L-lysine catabolic process to acetyl-CoA&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15351</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019475</classIRI>
<classLabel>L-lysine catabolic process to acetate</classLabel>
<deletedAxiom>&apos;L-lysine catabolic process to acetate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_30089</deletedAxiom>
<deletedAxiom>&apos;L-lysine catabolic process to acetate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_30089) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32550)</deletedAxiom>
<newAxiom>&apos;L-lysine catabolic process to acetate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_30089) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32550)</newAxiom>
<newAxiom>&apos;L-lysine catabolic process to acetate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_30089</newAxiom>
<newAxiom>&apos;L-lysine catabolic process to acetate&apos; SubClassOf &apos;acetate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019485</classIRI>
<classLabel>beta-alanine catabolic process to L-alanine</classLabel>
<deletedAxiom>&apos;beta-alanine catabolic process to L-alanine&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_32431</deletedAxiom>
<deletedAxiom>&apos;beta-alanine catabolic process to L-alanine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_32431) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16958)</deletedAxiom>
<newAxiom>&apos;beta-alanine catabolic process to L-alanine&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32431</newAxiom>
<newAxiom>&apos;beta-alanine catabolic process to L-alanine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32431) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16958)</newAxiom>
<newAxiom>&apos;beta-alanine catabolic process to L-alanine&apos; SubClassOf &apos;L-alanine metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019488</classIRI>
<classLabel>ribitol catabolic process to xylulose 5-phosphate</classLabel>
<deletedAxiom>&apos;ribitol catabolic process to xylulose 5-phosphate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_27354) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15963)</deletedAxiom>
<deletedAxiom>&apos;ribitol catabolic process to xylulose 5-phosphate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_27354</deletedAxiom>
<newAxiom>&apos;ribitol catabolic process to xylulose 5-phosphate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_27354) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15963)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019493</classIRI>
<classLabel>arginine catabolic process to proline</classLabel>
<deletedAxiom>&apos;arginine catabolic process to proline&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_32871</deletedAxiom>
<deletedAxiom>&apos;arginine catabolic process to proline&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_32871) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32695)</deletedAxiom>
<newAxiom>&apos;arginine catabolic process to proline&apos; SubClassOf &apos;proline metabolic process&apos;</newAxiom>
<newAxiom>&apos;arginine catabolic process to proline&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32871</newAxiom>
<newAxiom>&apos;arginine catabolic process to proline&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32871) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32695)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019495</classIRI>
<classLabel>proline catabolic process to 2-oxoglutarate</classLabel>
<deletedAxiom>&apos;proline catabolic process to 2-oxoglutarate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16810</deletedAxiom>
<deletedAxiom>&apos;proline catabolic process to 2-oxoglutarate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16810) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32871)</deletedAxiom>
<newAxiom>&apos;proline catabolic process to 2-oxoglutarate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16810) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32871)</newAxiom>
<newAxiom>&apos;proline catabolic process to 2-oxoglutarate&apos; SubClassOf &apos;2-oxoglutarate metabolic process&apos;</newAxiom>
<newAxiom>&apos;proline catabolic process to 2-oxoglutarate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16810</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019352</classIRI>
<classLabel>protoporphyrinogen IX biosynthetic process from glycine</classLabel>
<deletedAxiom>&apos;protoporphyrinogen IX biosynthetic process from glycine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32508</deletedAxiom>
<deletedAxiom>&apos;protoporphyrinogen IX biosynthetic process from glycine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32508) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15435)</deletedAxiom>
<newAxiom>&apos;protoporphyrinogen IX biosynthetic process from glycine&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32508</newAxiom>
<newAxiom>&apos;protoporphyrinogen IX biosynthetic process from glycine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15435) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32508)</newAxiom>
<newAxiom>&apos;protoporphyrinogen IX biosynthetic process from glycine&apos; SubClassOf &apos;glycine metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019353</classIRI>
<classLabel>protoporphyrinogen IX biosynthetic process from glutamate</classLabel>
<deletedAxiom>&apos;protoporphyrinogen IX biosynthetic process from glutamate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15435)</deletedAxiom>
<newAxiom>&apos;protoporphyrinogen IX biosynthetic process from glutamate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15435) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019355</classIRI>
<classLabel>nicotinamide nucleotide biosynthetic process from aspartate</classLabel>
<deletedAxiom>&apos;nicotinamide nucleotide biosynthetic process from aspartate&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_29995</deletedAxiom>
<deletedAxiom>&apos;nicotinamide nucleotide biosynthetic process from aspartate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_29995) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_25527)</deletedAxiom>
<newAxiom>&apos;nicotinamide nucleotide biosynthetic process from aspartate&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29995</newAxiom>
<newAxiom>&apos;nicotinamide nucleotide biosynthetic process from aspartate&apos; SubClassOf &apos;aspartate metabolic process&apos;</newAxiom>
<newAxiom>&apos;nicotinamide nucleotide biosynthetic process from aspartate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_25527) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29995)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019356</classIRI>
<classLabel>nicotinate nucleotide biosynthetic process from tryptophan</classLabel>
<deletedAxiom>&apos;nicotinate nucleotide biosynthetic process from tryptophan&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_27897) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_25534)</deletedAxiom>
<deletedAxiom>&apos;nicotinate nucleotide biosynthetic process from tryptophan&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_27897</deletedAxiom>
<newAxiom>&apos;nicotinate nucleotide biosynthetic process from tryptophan&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_25534) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_27897)</newAxiom>
<newAxiom>&apos;nicotinate nucleotide biosynthetic process from tryptophan&apos; SubClassOf &apos;tryptophan metabolic process&apos;</newAxiom>
<newAxiom>&apos;nicotinate nucleotide biosynthetic process from tryptophan&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_27897</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019360</classIRI>
<classLabel>nicotinamide nucleotide biosynthetic process from niacinamide</classLabel>
<deletedAxiom>&apos;nicotinamide nucleotide biosynthetic process from niacinamide&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17154</deletedAxiom>
<deletedAxiom>&apos;nicotinamide nucleotide biosynthetic process from niacinamide&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17154) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_25527)</deletedAxiom>
<newAxiom>&apos;nicotinamide nucleotide biosynthetic process from niacinamide&apos; SubClassOf &apos;nicotinamide metabolic process&apos;</newAxiom>
<newAxiom>&apos;nicotinamide nucleotide biosynthetic process from niacinamide&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17154</newAxiom>
<newAxiom>&apos;nicotinamide nucleotide biosynthetic process from niacinamide&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_25527) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17154)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032150</classIRI>
<classLabel>ubiquinone biosynthetic process from chorismate</classLabel>
<deletedAxiom>&apos;ubiquinone biosynthetic process from chorismate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_29748) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16389)</deletedAxiom>
<deletedAxiom>&apos;ubiquinone biosynthetic process from chorismate&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_29748</deletedAxiom>
<newAxiom>&apos;ubiquinone biosynthetic process from chorismate&apos; SubClassOf &apos;chorismate metabolic process&apos;</newAxiom>
<newAxiom>&apos;ubiquinone biosynthetic process from chorismate&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29748</newAxiom>
<newAxiom>&apos;ubiquinone biosynthetic process from chorismate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16389) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29748)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032180</classIRI>
<classLabel>ubiquinone biosynthetic process from tyrosine</classLabel>
<deletedAxiom>&apos;ubiquinone biosynthetic process from tyrosine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18186</deletedAxiom>
<deletedAxiom>&apos;ubiquinone biosynthetic process from tyrosine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18186) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16389)</deletedAxiom>
<newAxiom>&apos;ubiquinone biosynthetic process from tyrosine&apos; SubClassOf &apos;tyrosine metabolic process&apos;</newAxiom>
<newAxiom>&apos;ubiquinone biosynthetic process from tyrosine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16389) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18186)</newAxiom>
<newAxiom>&apos;ubiquinone biosynthetic process from tyrosine&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18186</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046550</classIRI>
<classLabel>(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5&apos;-adenosine biosynthetic process from asparagine</classLabel>
<deletedAxiom>&apos;(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5&apos;-adenosine biosynthetic process from asparagine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32660) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_60869)</deletedAxiom>
<deletedAxiom>&apos;(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5&apos;-adenosine biosynthetic process from asparagine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32660</deletedAxiom>
<newAxiom>&apos;(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5&apos;-adenosine biosynthetic process from asparagine&apos; SubClassOf &apos;asparagine metabolic process&apos;</newAxiom>
<newAxiom>&apos;(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5&apos;-adenosine biosynthetic process from asparagine&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32660</newAxiom>
<newAxiom>&apos;(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5&apos;-adenosine biosynthetic process from asparagine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_60869) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32660)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046327</classIRI>
<classLabel>glycerol biosynthetic process from pyruvate</classLabel>
<deletedAxiom>&apos;glycerol biosynthetic process from pyruvate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15361) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17754)</deletedAxiom>
<deletedAxiom>&apos;glycerol biosynthetic process from pyruvate&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15361</deletedAxiom>
<newAxiom>&apos;glycerol biosynthetic process from pyruvate&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15361</newAxiom>
<newAxiom>&apos;glycerol biosynthetic process from pyruvate&apos; SubClassOf &apos;pyruvate metabolic process&apos;</newAxiom>
<newAxiom>&apos;glycerol biosynthetic process from pyruvate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17754) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15361)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061719</classIRI>
<classLabel>glucose catabolic process to pyruvate utilizing ADP</classLabel>
<deletedAxiom>&apos;glucose catabolic process to pyruvate utilizing ADP&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has part&apos; some &apos;fructose-bisphosphate aldolase activity&apos;) and (&apos;has part&apos; some &apos;glucose-6-phosphate isomerase activity&apos;) and (&apos;has part&apos; some &apos;phosphoglycerate kinase activity&apos;) and (&apos;has part&apos; some &apos;phosphoglycerate mutase activity&apos;) and (&apos;has part&apos; some &apos;triose-phosphate isomerase activity&apos;) and (&apos;has part&apos; some &apos;glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) activity&apos;) and (&apos;has part&apos; some &apos;ADP-specific phosphofructokinase activity&apos;) and (&apos;starts with&apos; some &apos;ADP-specific glucokinase activity&apos;) and (&apos;ends with&apos; some &apos;pyruvate kinase activity&apos;) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15361) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17234)</deletedAxiom>
<newAxiom>&apos;glucose catabolic process to pyruvate utilizing ADP&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has part&apos; some &apos;fructose-bisphosphate aldolase activity&apos;) and (&apos;has part&apos; some &apos;glucose-6-phosphate isomerase activity&apos;) and (&apos;has part&apos; some &apos;phosphoglycerate kinase activity&apos;) and (&apos;has part&apos; some &apos;phosphoglycerate mutase activity&apos;) and (&apos;has part&apos; some &apos;triose-phosphate isomerase activity&apos;) and (&apos;has part&apos; some &apos;glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) activity&apos;) and (&apos;has part&apos; some &apos;ADP-specific phosphofructokinase activity&apos;) and (&apos;starts with&apos; some &apos;ADP-specific glucokinase activity&apos;) and (&apos;ends with&apos; some &apos;pyruvate kinase activity&apos;) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15361) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17234)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061718</classIRI>
<classLabel>glucose catabolic process to pyruvate</classLabel>
<deletedAxiom>&apos;glucose catabolic process to pyruvate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15361</deletedAxiom>
<deletedAxiom>&apos;glucose catabolic process to pyruvate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15361) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17234)</deletedAxiom>
<newAxiom>&apos;glucose catabolic process to pyruvate&apos; SubClassOf &apos;pyruvate metabolic process&apos;</newAxiom>
<newAxiom>&apos;glucose catabolic process to pyruvate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15361) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17234)</newAxiom>
<newAxiom>&apos;glucose catabolic process to pyruvate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15361</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061722</classIRI>
<classLabel>sulphoglycolysis</classLabel>
<deletedAxiom>&apos;sulphoglycolysis&apos; SubClassOf &apos;has participant&apos; some http://purl.obolibrary.org/obo/CHEBI_15846</deletedAxiom>
<newAxiom>&apos;sulphoglycolysis&apos; SubClassOf &apos;NADH metabolic process&apos;</newAxiom>
<newAxiom>&apos;sulphoglycolysis&apos; SubClassOf &apos;ATP metabolic process&apos;</newAxiom>
<newAxiom>&apos;sulphoglycolysis&apos; SubClassOf &apos;NAD metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061721</classIRI>
<classLabel>6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-)</classLabel>
<deletedAxiom>&apos;6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-)&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;starts with&apos; some &apos;6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde&apos;) and (&apos;ends with&apos; some &apos;3-sulfolactaldehyde reductase activity&apos;) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_77132)</deletedAxiom>
<newAxiom>&apos;6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-)&apos; SubClassOf &apos;alkanesulfonate metabolic process&apos;</newAxiom>
<newAxiom>&apos;6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-)&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_77138</newAxiom>
<newAxiom>&apos;6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-)&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;starts with&apos; some &apos;6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde&apos;) and (&apos;ends with&apos; some &apos;3-sulfolactaldehyde reductase activity&apos;) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_77138) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_77132)</newAxiom>
<newAxiom>&apos;6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-)&apos; SubClassOf &apos;propanediol metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061720</classIRI>
<classLabel>6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde</classLabel>
<deletedAxiom>&apos;6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16108</deletedAxiom>
<deletedAxiom>&apos;6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has part&apos; some &apos;6-deoxy-6-sulfofructose kinase activity&apos;) and (&apos;starts with&apos; some &apos;sulfoquinovose isomerase activity&apos;) and (&apos;ends with&apos; some &apos;6-deoxy-6-sulfofructose-1-phosphate aldolase activity&apos;) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16108) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_77132)</deletedAxiom>
<newAxiom>&apos;6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16108</newAxiom>
<newAxiom>&apos;6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde&apos; SubClassOf &apos;cellular ketone metabolic process&apos;</newAxiom>
<newAxiom>&apos;6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde&apos; SubClassOf &apos;organophosphate metabolic process&apos;</newAxiom>
<newAxiom>&apos;6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde&apos; SubClassOf &apos;cellular aldehyde metabolic process&apos;</newAxiom>
<newAxiom>&apos;6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde&apos; SubClassOf &apos;alkanesulfonate metabolic process&apos;</newAxiom>
<newAxiom>&apos;6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde&apos; SubClassOf &apos;phosphate-containing compound metabolic process&apos;</newAxiom>
<newAxiom>&apos;6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_77135</newAxiom>
<newAxiom>&apos;6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde&apos; SubClassOf &apos;primary alcohol metabolic process&apos;</newAxiom>
<newAxiom>&apos;6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has part&apos; some &apos;6-deoxy-6-sulfofructose kinase activity&apos;) and (&apos;starts with&apos; some &apos;sulfoquinovose isomerase activity&apos;) and (&apos;ends with&apos; some &apos;6-deoxy-6-sulfofructose-1-phosphate aldolase activity&apos;) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16108) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_77135) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_77132)</newAxiom>
<newAxiom>&apos;6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde&apos; SubClassOf &apos;secondary alcohol metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061727</classIRI>
<classLabel>methylglyoxal catabolic process to lactate</classLabel>
<deletedAxiom>&apos;methylglyoxal catabolic process to lactate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_24996) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17158)</deletedAxiom>
<deletedAxiom>&apos;methylglyoxal catabolic process to lactate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_24996</deletedAxiom>
<newAxiom>&apos;methylglyoxal catabolic process to lactate&apos; SubClassOf &apos;lactate metabolic process&apos;</newAxiom>
<newAxiom>&apos;methylglyoxal catabolic process to lactate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_24996) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17158)</newAxiom>
<newAxiom>&apos;methylglyoxal catabolic process to lactate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_24996</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061729</classIRI>
<classLabel>GDP-mannose biosynthetic process from fructose-6-phosphate</classLabel>
<deletedAxiom>&apos;GDP-mannose biosynthetic process from fructose-6-phosphate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;starts with&apos; some &apos;mannose-6-phosphate isomerase activity&apos;) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_78697) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_21168)</deletedAxiom>
<deletedAxiom>&apos;GDP-mannose biosynthetic process from fructose-6-phosphate&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_78697</deletedAxiom>
<newAxiom>&apos;GDP-mannose biosynthetic process from fructose-6-phosphate&apos; SubClassOf &apos;phosphate-containing compound metabolic process&apos;</newAxiom>
<newAxiom>&apos;GDP-mannose biosynthetic process from fructose-6-phosphate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;starts with&apos; some &apos;mannose-6-phosphate isomerase activity&apos;) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_21168) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_78697)</newAxiom>
<newAxiom>&apos;GDP-mannose biosynthetic process from fructose-6-phosphate&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_78697</newAxiom>
<newAxiom>&apos;GDP-mannose biosynthetic process from fructose-6-phosphate&apos; SubClassOf &apos;organophosphate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061728</classIRI>
<classLabel>GDP-mannose biosynthetic process from mannose</classLabel>
<deletedAxiom>&apos;GDP-mannose biosynthetic process from mannose&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;starts with&apos; some &apos;mannokinase activity&apos;) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_37684) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_21168)</deletedAxiom>
<deletedAxiom>&apos;GDP-mannose biosynthetic process from mannose&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_37684</deletedAxiom>
<newAxiom>&apos;GDP-mannose biosynthetic process from mannose&apos; SubClassOf &apos;mannose metabolic process&apos;</newAxiom>
<newAxiom>&apos;GDP-mannose biosynthetic process from mannose&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_37684</newAxiom>
<newAxiom>&apos;GDP-mannose biosynthetic process from mannose&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;starts with&apos; some &apos;mannokinase activity&apos;) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_21168) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_37684)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061706</classIRI>
<classLabel>glycolytic process from sucrose through glucose and fructose</classLabel>
<deletedAxiom>&apos;glycolytic process from sucrose through glucose and fructose&apos; SubClassOf &apos;glycolytic process through glucose-6-phosphate&apos;</deletedAxiom>
<newAxiom>&apos;glycolytic process from sucrose through glucose and fructose&apos; SubClassOf &apos;glycolytic process through fructose-6-phosphate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061620</classIRI>
<classLabel>glycolytic process through glucose-6-phosphate</classLabel>
<deletedAxiom>&apos;glycolytic process through glucose-6-phosphate&apos; EquivalentTo &apos;glycolytic process through fructose-6-phosphate&apos; and (&apos;has part&apos; some &apos;glucose-6-phosphate isomerase activity&apos;)</deletedAxiom>
<newAxiom>&apos;glycolytic process through glucose-6-phosphate&apos; EquivalentTo &apos;glycolytic process through fructose-6-phosphate&apos; and (&apos;has part&apos; some &apos;glucose-6-phosphate isomerase activity&apos;) and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_14314)</newAxiom>
<newAxiom>&apos;glycolytic process through glucose-6-phosphate&apos; SubClassOf &apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_14314</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061624</classIRI>
<classLabel>fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate</classLabel>
<deletedAxiom>&apos;fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17138</deletedAxiom>
<deletedAxiom>&apos;fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has part&apos; some &apos;triokinase activity&apos;) and (&apos;has part&apos; some &apos;fructose-1-phosphate aldolase activity&apos;) and (&apos;starts with&apos; some &apos;ketohexokinase activity&apos;) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17138) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_28757)</deletedAxiom>
<newAxiom>&apos;fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has part&apos; some &apos;triokinase activity&apos;) and (&apos;has part&apos; some &apos;fructose-1-phosphate aldolase activity&apos;) and (&apos;starts with&apos; some &apos;ketohexokinase activity&apos;) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17138) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_28757)</newAxiom>
<newAxiom>&apos;fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate&apos; SubClassOf &apos;glyceraldehyde-3-phosphate metabolic process&apos;</newAxiom>
<newAxiom>&apos;fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17138</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061621</classIRI>
<classLabel>canonical glycolysis</classLabel>
<deletedAxiom>&apos;canonical glycolysis&apos; SubClassOf &apos;has participant&apos; some http://purl.obolibrary.org/obo/CHEBI_15846</deletedAxiom>
<deletedAxiom>&apos;canonical glycolysis&apos; EquivalentTo &apos;glycolytic process through glucose-6-phosphate&apos; and (&apos;has part&apos; some &apos;glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity&apos;) and (&apos;has participant&apos; some http://purl.obolibrary.org/obo/CHEBI_15846) and (&apos;starts with&apos; some &apos;glucokinase activity&apos;) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16908) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17234)</deletedAxiom>
<deletedAxiom>&apos;canonical glycolysis&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16908</deletedAxiom>
<newAxiom>&apos;canonical glycolysis&apos; EquivalentTo &apos;glycolytic process through glucose-6-phosphate&apos; and (&apos;has part&apos; some &apos;glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity&apos;) and (&apos;starts with&apos; some &apos;glucokinase activity&apos;) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15846) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16908) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17234)</newAxiom>
<newAxiom>&apos;canonical glycolysis&apos; SubClassOf &apos;NADH regeneration&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061625</classIRI>
<classLabel>glycolytic process through fructose-1-phosphate</classLabel>
<deletedAxiom>&apos;glycolytic process through fructose-1-phosphate&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_28757</deletedAxiom>
<deletedAxiom>&apos;glycolytic process through fructose-1-phosphate&apos; EquivalentTo &apos;glycolytic process&apos; and (&apos;has part&apos; some &apos;triose-phosphate isomerase activity&apos;) and (&apos;starts with&apos; some &apos;fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate&apos;) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_28757)</deletedAxiom>
<newAxiom>&apos;glycolytic process through fructose-1-phosphate&apos; SubClassOf &apos;fructose catabolic process&apos;</newAxiom>
<newAxiom>&apos;glycolytic process through fructose-1-phosphate&apos; EquivalentTo &apos;glycolytic process&apos; and (&apos;has part&apos; some &apos;triose-phosphate isomerase activity&apos;) and (&apos;starts with&apos; some &apos;fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate&apos;) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_28757)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046034</classIRI>
<classLabel>ATP metabolic process</classLabel>
<deletedAxiom>&apos;ATP metabolic process&apos; SubClassOf &apos;purine ribonucleotide metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;ATP metabolic process&apos; SubClassOf &apos;drug metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;ATP metabolic process&apos; SubClassOf &apos;purine ribonucleoside triphosphate metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;ATP metabolic process&apos; SubClassOf &apos;has primary input or output&apos; some http://purl.obolibrary.org/obo/CHEBI_15422</deletedAxiom>
<deletedAxiom>&apos;ATP metabolic process&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has primary input or output&apos; some http://purl.obolibrary.org/obo/CHEBI_15422)</deletedAxiom>
<newAxiom>&apos;ATP metabolic process&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
<newAxiom>&apos;ATP metabolic process&apos; SubClassOf &apos;has participant&apos; some http://purl.obolibrary.org/obo/CHEBI_15422</newAxiom>
<newAxiom>&apos;ATP metabolic process&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has participant&apos; some http://purl.obolibrary.org/obo/CHEBI_15422)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036378</classIRI>
<classLabel>calcitriol biosynthetic process from calciol</classLabel>
<deletedAxiom>&apos;calcitriol biosynthetic process from calciol&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_28940</deletedAxiom>
<deletedAxiom>&apos;calcitriol biosynthetic process from calciol&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_28940) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17823)</deletedAxiom>
<newAxiom>&apos;calcitriol biosynthetic process from calciol&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_28940</newAxiom>
<newAxiom>&apos;calcitriol biosynthetic process from calciol&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17823) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_28940)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036241</classIRI>
<classLabel>glutamate catabolic process to 4-hydroxybutyrate</classLabel>
<deletedAxiom>&apos;glutamate catabolic process to 4-hydroxybutyrate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16724</deletedAxiom>
<deletedAxiom>&apos;glutamate catabolic process to 4-hydroxybutyrate&apos; EquivalentTo &apos;glutamate catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16724)</deletedAxiom>
<newAxiom>&apos;glutamate catabolic process to 4-hydroxybutyrate&apos; SubClassOf &apos;drug metabolic process&apos;</newAxiom>
<newAxiom>&apos;glutamate catabolic process to 4-hydroxybutyrate&apos; SubClassOf &apos;short-chain fatty acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;glutamate catabolic process to 4-hydroxybutyrate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16724</newAxiom>
<newAxiom>&apos;glutamate catabolic process to 4-hydroxybutyrate&apos; SubClassOf &apos;organic hydroxy compound metabolic process&apos;</newAxiom>
<newAxiom>&apos;glutamate catabolic process to 4-hydroxybutyrate&apos; EquivalentTo &apos;glutamate catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16724)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904023</classIRI>
<classLabel>regulation of glucose catabolic process to lactate via pyruvate</classLabel>
<newAxiom>&apos;regulation of glucose catabolic process to lactate via pyruvate&apos; SubClassOf &apos;regulation of NAD metabolic process&apos;</newAxiom>
<newAxiom>&apos;regulation of glucose catabolic process to lactate via pyruvate&apos; SubClassOf &apos;regulation of ATP metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904025</classIRI>
<classLabel>positive regulation of glucose catabolic process to lactate via pyruvate</classLabel>
<newAxiom>&apos;positive regulation of glucose catabolic process to lactate via pyruvate&apos; SubClassOf &apos;positive regulation of ATP metabolic process&apos;</newAxiom>
<newAxiom>&apos;positive regulation of glucose catabolic process to lactate via pyruvate&apos; SubClassOf &apos;positive regulation of NAD metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904024</classIRI>
<classLabel>negative regulation of glucose catabolic process to lactate via pyruvate</classLabel>
<newAxiom>&apos;negative regulation of glucose catabolic process to lactate via pyruvate&apos; SubClassOf &apos;negative regulation of ATP metabolic process&apos;</newAxiom>
<newAxiom>&apos;negative regulation of glucose catabolic process to lactate via pyruvate&apos; SubClassOf &apos;negative regulation of NAD metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036008</classIRI>
<classLabel>sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate</classLabel>
<deletedAxiom>&apos;sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_14314</deletedAxiom>
<deletedAxiom>&apos;sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15946</deletedAxiom>
<deletedAxiom>&apos;sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has part&apos; some &apos;fructokinase activity&apos;) and (&apos;has part&apos; some &apos;sucrose-phosphate phosphatase activity&apos;) and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_28757) and (&apos;starts with&apos; some &apos;protein-N(PI)-phosphohistidine-sucrose phosphotransferase system transporter activity&apos;) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_14314) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15946) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17992)</deletedAxiom>
<newAxiom>&apos;sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_14314</newAxiom>
<newAxiom>&apos;sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate&apos; SubClassOf &apos;glucose 6-phosphate metabolic process&apos;</newAxiom>
<newAxiom>&apos;sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate&apos; SubClassOf &apos;fructose 6-phosphate metabolic process&apos;</newAxiom>
<newAxiom>&apos;sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15946</newAxiom>
<newAxiom>&apos;sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has part&apos; some &apos;fructokinase activity&apos;) and (&apos;has part&apos; some &apos;sucrose-phosphate phosphatase activity&apos;) and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_28757) and (&apos;starts with&apos; some &apos;protein-N(PI)-phosphohistidine-sucrose phosphotransferase system transporter activity&apos;) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_14314) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15946) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17992)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002082</classIRI>
<classLabel>regulation of oxidative phosphorylation</classLabel>
<newAxiom>&apos;regulation of oxidative phosphorylation&apos; SubClassOf &apos;regulation of ATP metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903578</classIRI>
<classLabel>regulation of ATP metabolic process</classLabel>
<deletedAxiom>&apos;regulation of ATP metabolic process&apos; SubClassOf &apos;regulation of purine nucleotide metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of ATP metabolic process&apos; SubClassOf &apos;regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903579</classIRI>
<classLabel>negative regulation of ATP metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of ATP metabolic process&apos; SubClassOf &apos;negative regulation of purine nucleotide metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of ATP metabolic process&apos; SubClassOf &apos;negative regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903580</classIRI>
<classLabel>positive regulation of ATP metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of ATP metabolic process&apos; SubClassOf &apos;positive regulation of purine nucleotide metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of ATP metabolic process&apos; SubClassOf &apos;positive regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090324</classIRI>
<classLabel>negative regulation of oxidative phosphorylation</classLabel>
<newAxiom>&apos;negative regulation of oxidative phosphorylation&apos; SubClassOf &apos;negative regulation of ATP metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903862</classIRI>
<classLabel>positive regulation of oxidative phosphorylation</classLabel>
<newAxiom>&apos;positive regulation of oxidative phosphorylation&apos; SubClassOf &apos;positive regulation of ATP metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006754</classIRI>
<classLabel>ATP biosynthetic process</classLabel>
<newAxiom>&apos;ATP biosynthetic process&apos; SubClassOf &apos;drug metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006757</classIRI>
<classLabel>ATP generation from ADP</classLabel>
<deletedAxiom>&apos;ATP generation from ADP&apos; SubClassOf &apos;has primary input or output&apos; some http://purl.obolibrary.org/obo/CHEBI_456216</deletedAxiom>
<deletedAxiom>&apos;ATP generation from ADP&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_30616) and (&apos;has primary input or output&apos; some http://purl.obolibrary.org/obo/CHEBI_456216)</deletedAxiom>
<newAxiom>&apos;ATP generation from ADP&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_456216</newAxiom>
<newAxiom>&apos;ATP generation from ADP&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_456216) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_30616)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006735</classIRI>
<classLabel>NADH regeneration</classLabel>
<deletedAxiom>&apos;NADH regeneration&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16908) and (&apos;has primary input or output&apos; some http://purl.obolibrary.org/obo/CHEBI_15846)</deletedAxiom>
<deletedAxiom>&apos;NADH regeneration&apos; SubClassOf &apos;has primary input or output&apos; some http://purl.obolibrary.org/obo/CHEBI_15846</deletedAxiom>
<newAxiom>&apos;NADH regeneration&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15846</newAxiom>
<newAxiom>&apos;NADH regeneration&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15846) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16908)</newAxiom>
<newAxiom>&apos;NADH regeneration&apos; SubClassOf &apos;NAD metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006734</classIRI>
<classLabel>NADH metabolic process</classLabel>
<deletedAxiom>&apos;NADH metabolic process&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has primary input or output&apos; some http://purl.obolibrary.org/obo/CHEBI_16908)</deletedAxiom>
<deletedAxiom>&apos;NADH metabolic process&apos; SubClassOf &apos;has primary input or output&apos; some http://purl.obolibrary.org/obo/CHEBI_16908</deletedAxiom>
<deletedAxiom>&apos;NADH metabolic process&apos; SubClassOf &apos;NAD metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;NADH metabolic process&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
<newAxiom>&apos;NADH metabolic process&apos; SubClassOf &apos;has participant&apos; some http://purl.obolibrary.org/obo/CHEBI_16908</newAxiom>
<newAxiom>&apos;NADH metabolic process&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has participant&apos; some http://purl.obolibrary.org/obo/CHEBI_16908)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006739</classIRI>
<classLabel>NADP metabolic process</classLabel>
<deletedAxiom>&apos;NADP metabolic process&apos; SubClassOf &apos;nicotinamide nucleotide metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;NADP metabolic process&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has primary input or output&apos; some http://purl.obolibrary.org/obo/CHEBI_25523)</deletedAxiom>
<deletedAxiom>&apos;NADP metabolic process&apos; SubClassOf &apos;has primary input or output&apos; some http://purl.obolibrary.org/obo/CHEBI_25523</deletedAxiom>
<newAxiom>&apos;NADP metabolic process&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
<newAxiom>&apos;NADP metabolic process&apos; SubClassOf &apos;has participant&apos; some http://purl.obolibrary.org/obo/CHEBI_25523</newAxiom>
<newAxiom>&apos;NADP metabolic process&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has participant&apos; some http://purl.obolibrary.org/obo/CHEBI_25523)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006740</classIRI>
<classLabel>NADPH regeneration</classLabel>
<newAxiom>&apos;NADPH regeneration&apos; SubClassOf &apos;generation of precursor metabolites and energy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006742</classIRI>
<classLabel>NADP catabolic process</classLabel>
<newAxiom>&apos;NADP catabolic process&apos; SubClassOf &apos;nicotinamide nucleotide metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006535</classIRI>
<classLabel>cysteine biosynthetic process from serine</classLabel>
<deletedAxiom>&apos;cysteine biosynthetic process from serine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32836) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32458)</deletedAxiom>
<deletedAxiom>&apos;cysteine biosynthetic process from serine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32836</deletedAxiom>
<newAxiom>&apos;cysteine biosynthetic process from serine&apos; SubClassOf &apos;L-serine metabolic process&apos;</newAxiom>
<newAxiom>&apos;cysteine biosynthetic process from serine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32458) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32836)</newAxiom>
<newAxiom>&apos;cysteine biosynthetic process from serine&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32836</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006583</classIRI>
<classLabel>melanin biosynthetic process from tyrosine</classLabel>
<deletedAxiom>&apos;melanin biosynthetic process from tyrosine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18186</deletedAxiom>
<deletedAxiom>&apos;melanin biosynthetic process from tyrosine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18186) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_25179)</deletedAxiom>
<newAxiom>&apos;melanin biosynthetic process from tyrosine&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18186</newAxiom>
<newAxiom>&apos;melanin biosynthetic process from tyrosine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_25179) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18186)</newAxiom>
<newAxiom>&apos;melanin biosynthetic process from tyrosine&apos; SubClassOf &apos;tyrosine metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006585</classIRI>
<classLabel>dopamine biosynthetic process from tyrosine</classLabel>
<deletedAxiom>&apos;dopamine biosynthetic process from tyrosine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18186) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_18243)</deletedAxiom>
<deletedAxiom>&apos;dopamine biosynthetic process from tyrosine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18186</deletedAxiom>
<newAxiom>&apos;dopamine biosynthetic process from tyrosine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_18243) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18186)</newAxiom>
<newAxiom>&apos;dopamine biosynthetic process from tyrosine&apos; SubClassOf &apos;tyrosine metabolic process&apos;</newAxiom>
<newAxiom>&apos;dopamine biosynthetic process from tyrosine&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18186</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006587</classIRI>
<classLabel>serotonin biosynthetic process from tryptophan</classLabel>
<deletedAxiom>&apos;serotonin biosynthetic process from tryptophan&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_27897) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_28790)</deletedAxiom>
<deletedAxiom>&apos;serotonin biosynthetic process from tryptophan&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_27897</deletedAxiom>
<newAxiom>&apos;serotonin biosynthetic process from tryptophan&apos; SubClassOf &apos;tryptophan metabolic process&apos;</newAxiom>
<newAxiom>&apos;serotonin biosynthetic process from tryptophan&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_27897</newAxiom>
<newAxiom>&apos;serotonin biosynthetic process from tryptophan&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_28790) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_27897)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006201</classIRI>
<classLabel>GMP catabolic process to IMP</classLabel>
<deletedAxiom>&apos;GMP catabolic process to IMP&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17202</deletedAxiom>
<deletedAxiom>&apos;GMP catabolic process to IMP&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17202) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17345)</deletedAxiom>
<newAxiom>&apos;GMP catabolic process to IMP&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17202) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17345)</newAxiom>
<newAxiom>&apos;GMP catabolic process to IMP&apos; SubClassOf &apos;IMP biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006202</classIRI>
<classLabel>GMP catabolic process to guanine</classLabel>
<deletedAxiom>&apos;GMP catabolic process to guanine&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16235</deletedAxiom>
<deletedAxiom>&apos;GMP catabolic process to guanine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16235) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17345)</deletedAxiom>
<newAxiom>&apos;GMP catabolic process to guanine&apos; SubClassOf &apos;guanine biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;GMP catabolic process to guanine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16235) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17345)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045821</classIRI>
<classLabel>positive regulation of glycolytic process</classLabel>
<newAxiom>&apos;positive regulation of glycolytic process&apos; SubClassOf &apos;positive regulation of ATP metabolic process&apos;</newAxiom>
<newAxiom>&apos;positive regulation of glycolytic process&apos; SubClassOf &apos;positive regulation of purine nucleotide metabolic process&apos;</newAxiom>
<newAxiom>&apos;positive regulation of glycolytic process&apos; SubClassOf &apos;positive regulation of phosphorylation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045820</classIRI>
<classLabel>negative regulation of glycolytic process</classLabel>
<newAxiom>&apos;negative regulation of glycolytic process&apos; SubClassOf &apos;negative regulation of purine nucleotide metabolic process&apos;</newAxiom>
<newAxiom>&apos;negative regulation of glycolytic process&apos; SubClassOf &apos;negative regulation of phosphorylation&apos;</newAxiom>
<newAxiom>&apos;negative regulation of glycolytic process&apos; SubClassOf &apos;negative regulation of ATP metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070833</classIRI>
<classLabel>phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine</classLabel>
<deletedAxiom>&apos;phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_58190</deletedAxiom>
<deletedAxiom>&apos;phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_15868) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_58190) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_64482)</deletedAxiom>
<newAxiom>&apos;phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_58190</newAxiom>
<newAxiom>&apos;phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine&apos; SubClassOf &apos;primary amino compound metabolic process&apos;</newAxiom>
<newAxiom>&apos;phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_15868) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_64482) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_58190)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006110</classIRI>
<classLabel>regulation of glycolytic process</classLabel>
<newAxiom>&apos;regulation of glycolytic process&apos; SubClassOf &apos;regulation of purine nucleotide metabolic process&apos;</newAxiom>
<newAxiom>&apos;regulation of glycolytic process&apos; SubClassOf &apos;regulation of ATP metabolic process&apos;</newAxiom>
<newAxiom>&apos;regulation of glycolytic process&apos; SubClassOf &apos;regulation of phosphorylation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006116</classIRI>
<classLabel>NADH oxidation</classLabel>
<deletedAxiom>&apos;NADH oxidation&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15846) and (&apos;has primary input or output&apos; some http://purl.obolibrary.org/obo/CHEBI_16908)</deletedAxiom>
<newAxiom>&apos;NADH oxidation&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_16908</newAxiom>
<newAxiom>&apos;NADH oxidation&apos; SubClassOf &apos;NAD metabolic process&apos;</newAxiom>
<newAxiom>&apos;NADH oxidation&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_16908) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15846)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006119</classIRI>
<classLabel>oxidative phosphorylation</classLabel>
<newAxiom>&apos;oxidative phosphorylation&apos; SubClassOf &apos;ATP metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006127</classIRI>
<classLabel>glycerophosphate shuttle</classLabel>
<deletedAxiom>&apos;glycerophosphate shuttle&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_16908</deletedAxiom>
<deletedAxiom>&apos;glycerophosphate shuttle&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15846</deletedAxiom>
<newAxiom>&apos;glycerophosphate shuttle&apos; SubClassOf &apos;NADH oxidation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006176</classIRI>
<classLabel>dATP biosynthetic process from ADP</classLabel>
<deletedAxiom>&apos;dATP biosynthetic process from ADP&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_16761</deletedAxiom>
<deletedAxiom>&apos;dATP biosynthetic process from ADP&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_16761) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16284)</deletedAxiom>
<newAxiom>&apos;dATP biosynthetic process from ADP&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16284) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16761)</newAxiom>
<newAxiom>&apos;dATP biosynthetic process from ADP&apos; SubClassOf &apos;ADP metabolic process&apos;</newAxiom>
<newAxiom>&apos;dATP biosynthetic process from ADP&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16761</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006187</classIRI>
<classLabel>dGTP biosynthetic process from dGDP</classLabel>
<deletedAxiom>&apos;dGTP biosynthetic process from dGDP&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_28862</deletedAxiom>
<deletedAxiom>&apos;dGTP biosynthetic process from dGDP&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_28862) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16497)</deletedAxiom>
<newAxiom>&apos;dGTP biosynthetic process from dGDP&apos; SubClassOf &apos;dGDP metabolic process&apos;</newAxiom>
<newAxiom>&apos;dGTP biosynthetic process from dGDP&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_28862</newAxiom>
<newAxiom>&apos;dGTP biosynthetic process from dGDP&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16497) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_28862)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006086</classIRI>
<classLabel>acetyl-CoA biosynthetic process from pyruvate</classLabel>
<deletedAxiom>&apos;acetyl-CoA biosynthetic process from pyruvate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15361) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15351)</deletedAxiom>
<deletedAxiom>&apos;acetyl-CoA biosynthetic process from pyruvate&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15361</deletedAxiom>
<newAxiom>&apos;acetyl-CoA biosynthetic process from pyruvate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15351) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15361)</newAxiom>
<newAxiom>&apos;acetyl-CoA biosynthetic process from pyruvate&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15361</newAxiom>
<newAxiom>&apos;acetyl-CoA biosynthetic process from pyruvate&apos; SubClassOf &apos;pyruvate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006096</classIRI>
<classLabel>glycolytic process</classLabel>
<deletedAxiom>&apos;glycolytic process&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_30616</deletedAxiom>
<deletedAxiom>&apos;glycolytic process&apos; SubClassOf &apos;has participant&apos; some http://purl.obolibrary.org/obo/CHEBI_13390</deletedAxiom>
<deletedAxiom>&apos;glycolytic process&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15361</deletedAxiom>
<deletedAxiom>&apos;glycolytic process&apos; EquivalentTo &apos;carbohydrate catabolic process&apos; and (&apos;has part&apos; some &apos;phosphoglycerate kinase activity&apos;) and (&apos;has part&apos; some &apos;phosphoglycerate mutase activity&apos;) and (&apos;has part&apos; some &apos;phosphopyruvate hydratase activity&apos;) and (&apos;has part&apos; some &apos;glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity&apos;) and (&apos;has participant&apos; some http://purl.obolibrary.org/obo/CHEBI_13390) and (&apos;has participant&apos; some http://purl.obolibrary.org/obo/CHEBI_456216) and (&apos;ends with&apos; some &apos;pyruvate kinase activity&apos;) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_13392) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15361) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_30616)</deletedAxiom>
<deletedAxiom>&apos;glycolytic process&apos; SubClassOf &apos;has participant&apos; some http://purl.obolibrary.org/obo/CHEBI_456216</deletedAxiom>
<deletedAxiom>&apos;glycolytic process&apos; SubClassOf &apos;generation of precursor metabolites and energy&apos;</deletedAxiom>
<newAxiom>&apos;glycolytic process&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15361</newAxiom>
<newAxiom>&apos;glycolytic process&apos; SubClassOf &apos;ATP generation from ADP&apos;</newAxiom>
<newAxiom>&apos;glycolytic process&apos; EquivalentTo &apos;carbohydrate catabolic process&apos; and (&apos;has part&apos; some &apos;phosphoglycerate kinase activity&apos;) and (&apos;has part&apos; some &apos;phosphoglycerate mutase activity&apos;) and (&apos;has part&apos; some &apos;phosphopyruvate hydratase activity&apos;) and (&apos;has part&apos; some &apos;glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity&apos;) and (&apos;ends with&apos; some &apos;pyruvate kinase activity&apos;) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_13390) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_456216) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_13392) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_30616) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15361)</newAxiom>
<newAxiom>&apos;glycolytic process&apos; SubClassOf &apos;pyruvate metabolic process&apos;</newAxiom>
<newAxiom>&apos;glycolytic process&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_13390</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006098</classIRI>
<classLabel>pentose-phosphate shunt</classLabel>
<deletedAxiom>&apos;pentose-phosphate shunt&apos; SubClassOf &apos;metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;pentose-phosphate shunt&apos; SubClassOf &apos;NADP metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070689</classIRI>
<classLabel>L-threonine catabolic process to propionate</classLabel>
<deletedAxiom>&apos;L-threonine catabolic process to propionate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17272</deletedAxiom>
<deletedAxiom>&apos;L-threonine catabolic process to propionate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17272) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16857)</deletedAxiom>
<newAxiom>&apos;L-threonine catabolic process to propionate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17272</newAxiom>
<newAxiom>&apos;L-threonine catabolic process to propionate&apos; SubClassOf &apos;propionate metabolic process&apos;</newAxiom>
<newAxiom>&apos;L-threonine catabolic process to propionate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17272) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16857)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070690</classIRI>
<classLabel>L-threonine catabolic process to acetyl-CoA</classLabel>
<deletedAxiom>&apos;L-threonine catabolic process to acetyl-CoA&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15351) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16857)</deletedAxiom>
<deletedAxiom>&apos;L-threonine catabolic process to acetyl-CoA&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15351</deletedAxiom>
<newAxiom>&apos;L-threonine catabolic process to acetyl-CoA&apos; SubClassOf &apos;acetyl-CoA metabolic process&apos;</newAxiom>
<newAxiom>&apos;L-threonine catabolic process to acetyl-CoA&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15351</newAxiom>
<newAxiom>&apos;L-threonine catabolic process to acetyl-CoA&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15351) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16857)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033584</classIRI>
<classLabel>tyrosine biosynthetic process from chorismate via L-arogenate</classLabel>
<deletedAxiom>&apos;tyrosine biosynthetic process from chorismate via L-arogenate&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_29748</deletedAxiom>
<deletedAxiom>&apos;tyrosine biosynthetic process from chorismate via L-arogenate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_58180) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_29748) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_18186)</deletedAxiom>
<newAxiom>&apos;tyrosine biosynthetic process from chorismate via L-arogenate&apos; SubClassOf &apos;chorismate metabolic process&apos;</newAxiom>
<newAxiom>&apos;tyrosine biosynthetic process from chorismate via L-arogenate&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29748</newAxiom>
<newAxiom>&apos;tyrosine biosynthetic process from chorismate via L-arogenate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_58180) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_18186) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29748)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033586</classIRI>
<classLabel>L-phenylalanine biosynthetic process from chorismate via L-arogenate</classLabel>
<deletedAxiom>&apos;L-phenylalanine biosynthetic process from chorismate via L-arogenate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_58180) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_29748) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32486)</deletedAxiom>
<deletedAxiom>&apos;L-phenylalanine biosynthetic process from chorismate via L-arogenate&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_29748</deletedAxiom>
<newAxiom>&apos;L-phenylalanine biosynthetic process from chorismate via L-arogenate&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29748</newAxiom>
<newAxiom>&apos;L-phenylalanine biosynthetic process from chorismate via L-arogenate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_58180) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32486) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29748)</newAxiom>
<newAxiom>&apos;L-phenylalanine biosynthetic process from chorismate via L-arogenate&apos; SubClassOf &apos;chorismate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033585</classIRI>
<classLabel>L-phenylalanine biosynthetic process from chorismate via phenylpyruvate</classLabel>
<deletedAxiom>&apos;L-phenylalanine biosynthetic process from chorismate via phenylpyruvate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_30851) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_29748) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32486)</deletedAxiom>
<deletedAxiom>&apos;L-phenylalanine biosynthetic process from chorismate via phenylpyruvate&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_29748</deletedAxiom>
<newAxiom>&apos;L-phenylalanine biosynthetic process from chorismate via phenylpyruvate&apos; SubClassOf &apos;chorismate metabolic process&apos;</newAxiom>
<newAxiom>&apos;L-phenylalanine biosynthetic process from chorismate via phenylpyruvate&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29748</newAxiom>
<newAxiom>&apos;L-phenylalanine biosynthetic process from chorismate via phenylpyruvate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_30851) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32486) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29748)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033509</classIRI>
<classLabel>glutamate catabolic process to propionate</classLabel>
<deletedAxiom>&apos;glutamate catabolic process to propionate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17272) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987)</deletedAxiom>
<deletedAxiom>&apos;glutamate catabolic process to propionate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17272</deletedAxiom>
<newAxiom>&apos;glutamate catabolic process to propionate&apos; SubClassOf &apos;propionate metabolic process&apos;</newAxiom>
<newAxiom>&apos;glutamate catabolic process to propionate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17272</newAxiom>
<newAxiom>&apos;glutamate catabolic process to propionate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17272) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033506</classIRI>
<classLabel>glucosinolate biosynthetic process from homomethionine</classLabel>
<deletedAxiom>&apos;glucosinolate biosynthetic process from homomethionine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_62936</deletedAxiom>
<deletedAxiom>&apos;glucosinolate biosynthetic process from homomethionine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_62936) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_24279)</deletedAxiom>
<newAxiom>&apos;glucosinolate biosynthetic process from homomethionine&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_62936</newAxiom>
<newAxiom>&apos;glucosinolate biosynthetic process from homomethionine&apos; SubClassOf &apos;homomethionine metabolic process&apos;</newAxiom>
<newAxiom>&apos;glucosinolate biosynthetic process from homomethionine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_24279) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_62936)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033508</classIRI>
<classLabel>glutamate catabolic process to butyrate</classLabel>
<deletedAxiom>&apos;glutamate catabolic process to butyrate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17968</deletedAxiom>
<deletedAxiom>&apos;glutamate catabolic process to butyrate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17968) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987)</deletedAxiom>
<newAxiom>&apos;glutamate catabolic process to butyrate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17968) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987)</newAxiom>
<newAxiom>&apos;glutamate catabolic process to butyrate&apos; SubClassOf &apos;butyrate metabolic process&apos;</newAxiom>
<newAxiom>&apos;glutamate catabolic process to butyrate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17968</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033507</classIRI>
<classLabel>glucosinolate biosynthetic process from phenylalanine</classLabel>
<deletedAxiom>&apos;glucosinolate biosynthetic process from phenylalanine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32504) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_24279)</deletedAxiom>
<deletedAxiom>&apos;glucosinolate biosynthetic process from phenylalanine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32504</deletedAxiom>
<newAxiom>&apos;glucosinolate biosynthetic process from phenylalanine&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32504</newAxiom>
<newAxiom>&apos;glucosinolate biosynthetic process from phenylalanine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_24279) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32504)</newAxiom>
<newAxiom>&apos;glucosinolate biosynthetic process from phenylalanine&apos; SubClassOf &apos;aromatic amino acid family metabolic process&apos;</newAxiom>
<newAxiom>&apos;glucosinolate biosynthetic process from phenylalanine&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033526</classIRI>
<classLabel>tetrapyrrole biosynthetic process from glutamate</classLabel>
<deletedAxiom>&apos;tetrapyrrole biosynthetic process from glutamate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_26932)</deletedAxiom>
<deletedAxiom>&apos;tetrapyrrole biosynthetic process from glutamate&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987</deletedAxiom>
<newAxiom>&apos;tetrapyrrole biosynthetic process from glutamate&apos; SubClassOf &apos;glutamate metabolic process&apos;</newAxiom>
<newAxiom>&apos;tetrapyrrole biosynthetic process from glutamate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_26932) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987)</newAxiom>
<newAxiom>&apos;tetrapyrrole biosynthetic process from glutamate&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_29987</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033527</classIRI>
<classLabel>tetrapyrrole biosynthetic process from glycine and succinyl-CoA</classLabel>
<deletedAxiom>&apos;tetrapyrrole biosynthetic process from glycine and succinyl-CoA&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15380</deletedAxiom>
<deletedAxiom>&apos;tetrapyrrole biosynthetic process from glycine and succinyl-CoA&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32508</deletedAxiom>
<deletedAxiom>&apos;tetrapyrrole biosynthetic process from glycine and succinyl-CoA&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15380) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32508) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_26932)</deletedAxiom>
<newAxiom>&apos;tetrapyrrole biosynthetic process from glycine and succinyl-CoA&apos; SubClassOf &apos;succinyl-CoA metabolic process&apos;</newAxiom>
<newAxiom>&apos;tetrapyrrole biosynthetic process from glycine and succinyl-CoA&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_26932) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15380) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32508)</newAxiom>
<newAxiom>&apos;tetrapyrrole biosynthetic process from glycine and succinyl-CoA&apos; SubClassOf &apos;glycine metabolic process&apos;</newAxiom>
<newAxiom>&apos;tetrapyrrole biosynthetic process from glycine and succinyl-CoA&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15380</newAxiom>
<newAxiom>&apos;tetrapyrrole biosynthetic process from glycine and succinyl-CoA&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32508</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033516</classIRI>
<classLabel>L-methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine</classLabel>
<deletedAxiom>&apos;L-methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_15961) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15699) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16643)</deletedAxiom>
<newAxiom>&apos;L-methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_15961) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16643) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15699)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033317</classIRI>
<classLabel>pantothenate biosynthetic process from valine</classLabel>
<deletedAxiom>&apos;pantothenate biosynthetic process from valine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32859</deletedAxiom>
<deletedAxiom>&apos;pantothenate biosynthetic process from valine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32859) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16454)</deletedAxiom>
<newAxiom>&apos;pantothenate biosynthetic process from valine&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32859</newAxiom>
<newAxiom>&apos;pantothenate biosynthetic process from valine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16454) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32859)</newAxiom>
<newAxiom>&apos;pantothenate biosynthetic process from valine&apos; SubClassOf &apos;valine metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033318</classIRI>
<classLabel>pantothenate biosynthetic process from 2-dehydropantolactone</classLabel>
<deletedAxiom>&apos;pantothenate biosynthetic process from 2-dehydropantolactone&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18395) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16454)</deletedAxiom>
<deletedAxiom>&apos;pantothenate biosynthetic process from 2-dehydropantolactone&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18395</deletedAxiom>
<newAxiom>&apos;pantothenate biosynthetic process from 2-dehydropantolactone&apos; SubClassOf &apos;heterocycle metabolic process&apos;</newAxiom>
<newAxiom>&apos;pantothenate biosynthetic process from 2-dehydropantolactone&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16454) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18395)</newAxiom>
<newAxiom>&apos;pantothenate biosynthetic process from 2-dehydropantolactone&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18395</newAxiom>
<newAxiom>&apos;pantothenate biosynthetic process from 2-dehydropantolactone&apos; SubClassOf &apos;organic cyclic compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033390</classIRI>
<classLabel>putrescine biosynthetic process from arginine via N-carbamoylputrescine</classLabel>
<deletedAxiom>&apos;putrescine biosynthetic process from arginine via N-carbamoylputrescine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_17902) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32695) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17148)</deletedAxiom>
<newAxiom>&apos;putrescine biosynthetic process from arginine via N-carbamoylputrescine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_17902) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17148) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32695)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033388</classIRI>
<classLabel>putrescine biosynthetic process from arginine</classLabel>
<deletedAxiom>&apos;putrescine biosynthetic process from arginine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32695) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17148)</deletedAxiom>
<deletedAxiom>&apos;putrescine biosynthetic process from arginine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32695</deletedAxiom>
<newAxiom>&apos;putrescine biosynthetic process from arginine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17148) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32695)</newAxiom>
<newAxiom>&apos;putrescine biosynthetic process from arginine&apos; SubClassOf &apos;arginine metabolic process&apos;</newAxiom>
<newAxiom>&apos;putrescine biosynthetic process from arginine&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32695</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033387</classIRI>
<classLabel>putrescine biosynthetic process from ornithine</classLabel>
<deletedAxiom>&apos;putrescine biosynthetic process from ornithine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32964</deletedAxiom>
<deletedAxiom>&apos;putrescine biosynthetic process from ornithine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32964) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17148)</deletedAxiom>
<newAxiom>&apos;putrescine biosynthetic process from ornithine&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32964</newAxiom>
<newAxiom>&apos;putrescine biosynthetic process from ornithine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17148) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32964)</newAxiom>
<newAxiom>&apos;putrescine biosynthetic process from ornithine&apos; SubClassOf &apos;ornithine metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033389</classIRI>
<classLabel>putrescine biosynthetic process from arginine, using agmatinase</classLabel>
<deletedAxiom>&apos;putrescine biosynthetic process from arginine, using agmatinase&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_17431) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_32695) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17148)</deletedAxiom>
<newAxiom>&apos;putrescine biosynthetic process from arginine, using agmatinase&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some http://purl.obolibrary.org/obo/CHEBI_17431) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17148) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_32695)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052776</classIRI>
<classLabel>diacetylchitobiose catabolic process to glucosamine and acetate</classLabel>
<deletedAxiom>&apos;diacetylchitobiose catabolic process to glucosamine and acetate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_30089) and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_5417) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_28681)</deletedAxiom>
<deletedAxiom>&apos;diacetylchitobiose catabolic process to glucosamine and acetate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_5417</deletedAxiom>
<deletedAxiom>&apos;diacetylchitobiose catabolic process to glucosamine and acetate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_30089</deletedAxiom>
<newAxiom>&apos;diacetylchitobiose catabolic process to glucosamine and acetate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_30089</newAxiom>
<newAxiom>&apos;diacetylchitobiose catabolic process to glucosamine and acetate&apos; SubClassOf &apos;glucosamine metabolic process&apos;</newAxiom>
<newAxiom>&apos;diacetylchitobiose catabolic process to glucosamine and acetate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_5417</newAxiom>
<newAxiom>&apos;diacetylchitobiose catabolic process to glucosamine and acetate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_30089) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_5417) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_28681)</newAxiom>
<newAxiom>&apos;diacetylchitobiose catabolic process to glucosamine and acetate&apos; SubClassOf &apos;acetate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990491</classIRI>
<classLabel>methane biosynthetic process from methanol and hydrogen</classLabel>
<deletedAxiom>&apos;methane biosynthetic process from methanol and hydrogen&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18276</deletedAxiom>
<deletedAxiom>&apos;methane biosynthetic process from methanol and hydrogen&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17790) and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18276) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16183)</deletedAxiom>
<newAxiom>&apos;methane biosynthetic process from methanol and hydrogen&apos; SubClassOf &apos;methanol metabolic process&apos;</newAxiom>
<newAxiom>&apos;methane biosynthetic process from methanol and hydrogen&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16183) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17790) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18276)</newAxiom>
<newAxiom>&apos;methane biosynthetic process from methanol and hydrogen&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17790</newAxiom>
<newAxiom>&apos;methane biosynthetic process from methanol and hydrogen&apos; SubClassOf &apos;hydrogen metabolic process&apos;</newAxiom>
<newAxiom>&apos;methane biosynthetic process from methanol and hydrogen&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18276</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052711</classIRI>
<classLabel>ergothioneine biosynthesis from N-alpha,N-alpha,N-alpha-trimethyl-L-histidine</classLabel>
<deletedAxiom>&apos;ergothioneine biosynthesis from N-alpha,N-alpha,N-alpha-trimethyl-L-histidine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_4828) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15781)</deletedAxiom>
<deletedAxiom>&apos;ergothioneine biosynthesis from N-alpha,N-alpha,N-alpha-trimethyl-L-histidine&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_4828</deletedAxiom>
<newAxiom>&apos;ergothioneine biosynthesis from N-alpha,N-alpha,N-alpha-trimethyl-L-histidine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_4828) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15781)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902031</classIRI>
<classLabel>regulation of NADP metabolic process</classLabel>
<deletedAxiom>&apos;regulation of NADP metabolic process&apos; SubClassOf &apos;regulation of coenzyme metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of NADP metabolic process&apos; SubClassOf &apos;regulation of nucleotide metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of NADP metabolic process&apos; SubClassOf &apos;regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001172</classIRI>
<classLabel>positive regulation of glycolytic fermentation to ethanol</classLabel>
<newAxiom>&apos;positive regulation of glycolytic fermentation to ethanol&apos; SubClassOf &apos;positive regulation of ATP metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001154</classIRI>
<classLabel>regulation of glycolytic fermentation to ethanol</classLabel>
<newAxiom>&apos;regulation of glycolytic fermentation to ethanol&apos; SubClassOf &apos;regulation of ATP metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001158</classIRI>
<classLabel>positive regulation of proline catabolic process to glutamate</classLabel>
<newAxiom>&apos;positive regulation of proline catabolic process to glutamate&apos; SubClassOf &apos;positive regulation of glutamate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001157</classIRI>
<classLabel>negative regulation of proline catabolic process to glutamate</classLabel>
<newAxiom>&apos;negative regulation of proline catabolic process to glutamate&apos; SubClassOf &apos;negative regulation of glutamate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001156</classIRI>
<classLabel>regulation of proline catabolic process to glutamate</classLabel>
<newAxiom>&apos;regulation of proline catabolic process to glutamate&apos; SubClassOf &apos;regulation of glutamate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001155</classIRI>
<classLabel>negative regulation of glycolytic fermentation to ethanol</classLabel>
<newAxiom>&apos;negative regulation of glycolytic fermentation to ethanol&apos; SubClassOf &apos;negative regulation of ATP metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001129</classIRI>
<classLabel>methane biosynthetic process from dimethylamine</classLabel>
<deletedAxiom>&apos;methane biosynthetic process from dimethylamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17170) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16183)</deletedAxiom>
<deletedAxiom>&apos;methane biosynthetic process from dimethylamine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17170</deletedAxiom>
<newAxiom>&apos;methane biosynthetic process from dimethylamine&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17170</newAxiom>
<newAxiom>&apos;methane biosynthetic process from dimethylamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16183) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17170)</newAxiom>
<newAxiom>&apos;methane biosynthetic process from dimethylamine&apos; SubClassOf &apos;ammonium ion metabolic process&apos;</newAxiom>
<newAxiom>&apos;methane biosynthetic process from dimethylamine&apos; SubClassOf &apos;amine metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001128</classIRI>
<classLabel>methane biosynthetic process from methylamine</classLabel>
<deletedAxiom>&apos;methane biosynthetic process from methylamine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_59338</deletedAxiom>
<deletedAxiom>&apos;methane biosynthetic process from methylamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_59338) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16183)</deletedAxiom>
<newAxiom>&apos;methane biosynthetic process from methylamine&apos; SubClassOf &apos;methylamine metabolic process&apos;</newAxiom>
<newAxiom>&apos;methane biosynthetic process from methylamine&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_59338</newAxiom>
<newAxiom>&apos;methane biosynthetic process from methylamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16183) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_59338)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001127</classIRI>
<classLabel>methane biosynthetic process from formic acid</classLabel>
<deletedAxiom>&apos;methane biosynthetic process from formic acid&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15740</deletedAxiom>
<deletedAxiom>&apos;methane biosynthetic process from formic acid&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_15740) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16183)</deletedAxiom>
<newAxiom>&apos;methane biosynthetic process from formic acid&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16183) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15740)</newAxiom>
<newAxiom>&apos;methane biosynthetic process from formic acid&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15740</newAxiom>
<newAxiom>&apos;methane biosynthetic process from formic acid&apos; SubClassOf &apos;formate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001132</classIRI>
<classLabel>methane biosynthetic process from 3-(methylthio)propionic acid</classLabel>
<deletedAxiom>&apos;methane biosynthetic process from 3-(methylthio)propionic acid&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_49016) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16183)</deletedAxiom>
<deletedAxiom>&apos;methane biosynthetic process from 3-(methylthio)propionic acid&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_49016</deletedAxiom>
<newAxiom>&apos;methane biosynthetic process from 3-(methylthio)propionic acid&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_49016</newAxiom>
<newAxiom>&apos;methane biosynthetic process from 3-(methylthio)propionic acid&apos; SubClassOf &apos;sulfur compound metabolic process&apos;</newAxiom>
<newAxiom>&apos;methane biosynthetic process from 3-(methylthio)propionic acid&apos; SubClassOf &apos;toxin metabolic process&apos;</newAxiom>
<newAxiom>&apos;methane biosynthetic process from 3-(methylthio)propionic acid&apos; SubClassOf &apos;fatty acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;methane biosynthetic process from 3-(methylthio)propionic acid&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16183) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_49016)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001131</classIRI>
<classLabel>methane biosynthetic process from dimethyl sulfide</classLabel>
<deletedAxiom>&apos;methane biosynthetic process from dimethyl sulfide&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17437) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16183)</deletedAxiom>
<deletedAxiom>&apos;methane biosynthetic process from dimethyl sulfide&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17437</deletedAxiom>
<newAxiom>&apos;methane biosynthetic process from dimethyl sulfide&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17437</newAxiom>
<newAxiom>&apos;methane biosynthetic process from dimethyl sulfide&apos; SubClassOf &apos;sulfur compound metabolic process&apos;</newAxiom>
<newAxiom>&apos;methane biosynthetic process from dimethyl sulfide&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16183) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17437)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001130</classIRI>
<classLabel>methane biosynthetic process from trimethylamine</classLabel>
<deletedAxiom>&apos;methane biosynthetic process from trimethylamine&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18139</deletedAxiom>
<deletedAxiom>&apos;methane biosynthetic process from trimethylamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_18139) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16183)</deletedAxiom>
<newAxiom>&apos;methane biosynthetic process from trimethylamine&apos; SubClassOf &apos;ammonium ion metabolic process&apos;</newAxiom>
<newAxiom>&apos;methane biosynthetic process from trimethylamine&apos; SubClassOf &apos;amine metabolic process&apos;</newAxiom>
<newAxiom>&apos;methane biosynthetic process from trimethylamine&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18139</newAxiom>
<newAxiom>&apos;methane biosynthetic process from trimethylamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16183) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18139)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001134</classIRI>
<classLabel>methane biosynthetic process from carbon monoxide</classLabel>
<deletedAxiom>&apos;methane biosynthetic process from carbon monoxide&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17245) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16183)</deletedAxiom>
<deletedAxiom>&apos;methane biosynthetic process from carbon monoxide&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17245</deletedAxiom>
<newAxiom>&apos;methane biosynthetic process from carbon monoxide&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16183) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17245)</newAxiom>
<newAxiom>&apos;methane biosynthetic process from carbon monoxide&apos; SubClassOf &apos;drug metabolic process&apos;</newAxiom>
<newAxiom>&apos;methane biosynthetic process from carbon monoxide&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17245</newAxiom>
<newAxiom>&apos;methane biosynthetic process from carbon monoxide&apos; SubClassOf &apos;neurotransmitter metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001133</classIRI>
<classLabel>methane biosynthetic process from methanethiol</classLabel>
<deletedAxiom>&apos;methane biosynthetic process from methanethiol&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_16007</deletedAxiom>
<deletedAxiom>&apos;methane biosynthetic process from methanethiol&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_16007) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16183)</deletedAxiom>
<newAxiom>&apos;methane biosynthetic process from methanethiol&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16007</newAxiom>
<newAxiom>&apos;methane biosynthetic process from methanethiol&apos; SubClassOf &apos;sulfur compound metabolic process&apos;</newAxiom>
<newAxiom>&apos;methane biosynthetic process from methanethiol&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16183) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_16007)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990966</classIRI>
<classLabel>ATP generation from poly-ADP-D-ribose</classLabel>
<newAxiom>&apos;ATP generation from poly-ADP-D-ribose&apos; SubClassOf &apos;carbohydrate derivative metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902700</classIRI>
<classLabel>pentose catabolic process to butan-1-ol</classLabel>
<deletedAxiom>&apos;pentose catabolic process to butan-1-ol&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_28885</deletedAxiom>
<deletedAxiom>&apos;pentose catabolic process to butan-1-ol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_28885) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_25901)</deletedAxiom>
<newAxiom>&apos;pentose catabolic process to butan-1-ol&apos; SubClassOf &apos;1-butanol metabolic process&apos;</newAxiom>
<newAxiom>&apos;pentose catabolic process to butan-1-ol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_28885) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_25901)</newAxiom>
<newAxiom>&apos;pentose catabolic process to butan-1-ol&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_28885</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902702</classIRI>
<classLabel>hexose catabolic process to propan-2-ol</classLabel>
<deletedAxiom>&apos;hexose catabolic process to propan-2-ol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17824) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18133)</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to propan-2-ol&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17824</deletedAxiom>
<newAxiom>&apos;hexose catabolic process to propan-2-ol&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17824</newAxiom>
<newAxiom>&apos;hexose catabolic process to propan-2-ol&apos; SubClassOf &apos;propan-2-ol metabolic process&apos;</newAxiom>
<newAxiom>&apos;hexose catabolic process to propan-2-ol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17824) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18133)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902701</classIRI>
<classLabel>pentose catabolic process to propan-2-ol</classLabel>
<deletedAxiom>&apos;pentose catabolic process to propan-2-ol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17824) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_25901)</deletedAxiom>
<deletedAxiom>&apos;pentose catabolic process to propan-2-ol&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17824</deletedAxiom>
<newAxiom>&apos;pentose catabolic process to propan-2-ol&apos; SubClassOf &apos;propan-2-ol metabolic process&apos;</newAxiom>
<newAxiom>&apos;pentose catabolic process to propan-2-ol&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17824</newAxiom>
<newAxiom>&apos;pentose catabolic process to propan-2-ol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17824) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_25901)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902704</classIRI>
<classLabel>hexose catabolic process to acetone</classLabel>
<deletedAxiom>&apos;hexose catabolic process to acetone&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15347</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to acetone&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_15347) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18133)</deletedAxiom>
<newAxiom>&apos;hexose catabolic process to acetone&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15347</newAxiom>
<newAxiom>&apos;hexose catabolic process to acetone&apos; SubClassOf &apos;acetone metabolic process&apos;</newAxiom>
<newAxiom>&apos;hexose catabolic process to acetone&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_15347) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18133)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902703</classIRI>
<classLabel>hexose catabolic process to butan-1-ol</classLabel>
<deletedAxiom>&apos;hexose catabolic process to butan-1-ol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_28885) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18133)</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to butan-1-ol&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_28885</deletedAxiom>
<newAxiom>&apos;hexose catabolic process to butan-1-ol&apos; SubClassOf &apos;1-butanol metabolic process&apos;</newAxiom>
<newAxiom>&apos;hexose catabolic process to butan-1-ol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_28885) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18133)</newAxiom>
<newAxiom>&apos;hexose catabolic process to butan-1-ol&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_28885</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902706</classIRI>
<classLabel>hexose catabolic process to acetate</classLabel>
<deletedAxiom>&apos;hexose catabolic process to acetate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_30089) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18133)</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to acetate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_30089</deletedAxiom>
<newAxiom>&apos;hexose catabolic process to acetate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_30089) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18133)</newAxiom>
<newAxiom>&apos;hexose catabolic process to acetate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_30089</newAxiom>
<newAxiom>&apos;hexose catabolic process to acetate&apos; SubClassOf &apos;acetate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902705</classIRI>
<classLabel>hexose catabolic process to butyrate</classLabel>
<deletedAxiom>&apos;hexose catabolic process to butyrate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17968</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to butyrate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17968) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18133)</deletedAxiom>
<newAxiom>&apos;hexose catabolic process to butyrate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17968) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18133)</newAxiom>
<newAxiom>&apos;hexose catabolic process to butyrate&apos; SubClassOf &apos;butyrate metabolic process&apos;</newAxiom>
<newAxiom>&apos;hexose catabolic process to butyrate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17968</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902707</classIRI>
<classLabel>hexose catabolic process to ethanol</classLabel>
<deletedAxiom>&apos;hexose catabolic process to ethanol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16236) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18133)</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to ethanol&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_16236</deletedAxiom>
<newAxiom>&apos;hexose catabolic process to ethanol&apos; SubClassOf &apos;ethanol metabolic process&apos;</newAxiom>
<newAxiom>&apos;hexose catabolic process to ethanol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16236) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_18133)</newAxiom>
<newAxiom>&apos;hexose catabolic process to ethanol&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_16236</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902689</classIRI>
<classLabel>negative regulation of NAD metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of NAD metabolic process&apos; SubClassOf &apos;negative regulation of coenzyme metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of NAD metabolic process&apos; SubClassOf &apos;negative regulation of nucleotide metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of NAD metabolic process&apos; SubClassOf &apos;negative regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902688</classIRI>
<classLabel>regulation of NAD metabolic process</classLabel>
<deletedAxiom>&apos;regulation of NAD metabolic process&apos; SubClassOf &apos;regulation of nucleotide metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of NAD metabolic process&apos; SubClassOf &apos;regulation of coenzyme metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of NAD metabolic process&apos; SubClassOf &apos;regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902690</classIRI>
<classLabel>positive regulation of NAD metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of NAD metabolic process&apos; SubClassOf &apos;positive regulation of nucleotide metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of NAD metabolic process&apos; SubClassOf &apos;positive regulation of coenzyme metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of NAD metabolic process&apos; SubClassOf &apos;positive regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902696</classIRI>
<classLabel>glycine catabolic process to isobutanol</classLabel>
<deletedAxiom>&apos;glycine catabolic process to isobutanol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_46645) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15428)</deletedAxiom>
<deletedAxiom>&apos;glycine catabolic process to isobutanol&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_46645</deletedAxiom>
<newAxiom>&apos;glycine catabolic process to isobutanol&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_46645</newAxiom>
<newAxiom>&apos;glycine catabolic process to isobutanol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_46645) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15428)</newAxiom>
<newAxiom>&apos;glycine catabolic process to isobutanol&apos; SubClassOf &apos;isobutanol metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902698</classIRI>
<classLabel>pentose catabolic process to butyrate</classLabel>
<deletedAxiom>&apos;pentose catabolic process to butyrate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17968) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_25901)</deletedAxiom>
<deletedAxiom>&apos;pentose catabolic process to butyrate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_17968</deletedAxiom>
<newAxiom>&apos;pentose catabolic process to butyrate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17968</newAxiom>
<newAxiom>&apos;pentose catabolic process to butyrate&apos; SubClassOf &apos;butyrate metabolic process&apos;</newAxiom>
<newAxiom>&apos;pentose catabolic process to butyrate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_17968) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_25901)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902697</classIRI>
<classLabel>valine catabolic process to isobutanol</classLabel>
<deletedAxiom>&apos;valine catabolic process to isobutanol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_46645) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_27266)</deletedAxiom>
<deletedAxiom>&apos;valine catabolic process to isobutanol&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_46645</deletedAxiom>
<newAxiom>&apos;valine catabolic process to isobutanol&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_46645</newAxiom>
<newAxiom>&apos;valine catabolic process to isobutanol&apos; SubClassOf &apos;isobutanol metabolic process&apos;</newAxiom>
<newAxiom>&apos;valine catabolic process to isobutanol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_46645) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_27266)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902699</classIRI>
<classLabel>pentose catabolic process to acetate</classLabel>
<deletedAxiom>&apos;pentose catabolic process to acetate&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_30089</deletedAxiom>
<deletedAxiom>&apos;pentose catabolic process to acetate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_30089) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_25901)</deletedAxiom>
<newAxiom>&apos;pentose catabolic process to acetate&apos; SubClassOf &apos;acetate metabolic process&apos;</newAxiom>
<newAxiom>&apos;pentose catabolic process to acetate&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_30089</newAxiom>
<newAxiom>&apos;pentose catabolic process to acetate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_30089) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_25901)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042459</classIRI>
<classLabel>octopine catabolic process to proline</classLabel>
<deletedAxiom>&apos;octopine catabolic process to proline&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_32871) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15805)</deletedAxiom>
<deletedAxiom>&apos;octopine catabolic process to proline&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_32871</deletedAxiom>
<newAxiom>&apos;octopine catabolic process to proline&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32871</newAxiom>
<newAxiom>&apos;octopine catabolic process to proline&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32871) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_15805)</newAxiom>
<newAxiom>&apos;octopine catabolic process to proline&apos; SubClassOf &apos;proline metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042458</classIRI>
<classLabel>nopaline catabolic process to proline</classLabel>
<deletedAxiom>&apos;nopaline catabolic process to proline&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_32871) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17249)</deletedAxiom>
<deletedAxiom>&apos;nopaline catabolic process to proline&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_32871</deletedAxiom>
<newAxiom>&apos;nopaline catabolic process to proline&apos; SubClassOf &apos;proline metabolic process&apos;</newAxiom>
<newAxiom>&apos;nopaline catabolic process to proline&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32871) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17249)</newAxiom>
<newAxiom>&apos;nopaline catabolic process to proline&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_32871</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902924</classIRI>
<classLabel>poly(hydroxyalkanoate) biosynthetic process from glucose</classLabel>
<deletedAxiom>&apos;poly(hydroxyalkanoate) biosynthetic process from glucose&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17234</deletedAxiom>
<deletedAxiom>&apos;poly(hydroxyalkanoate) biosynthetic process from glucose&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_17234) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_53387)</deletedAxiom>
<newAxiom>&apos;poly(hydroxyalkanoate) biosynthetic process from glucose&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_53387) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17234)</newAxiom>
<newAxiom>&apos;poly(hydroxyalkanoate) biosynthetic process from glucose&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_17234</newAxiom>
<newAxiom>&apos;poly(hydroxyalkanoate) biosynthetic process from glucose&apos; SubClassOf &apos;glucose metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902925</classIRI>
<classLabel>poly(hydroxyalkanoate) biosynthetic process from fatty acid</classLabel>
<deletedAxiom>&apos;poly(hydroxyalkanoate) biosynthetic process from fatty acid&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_35366</deletedAxiom>
<deletedAxiom>&apos;poly(hydroxyalkanoate) biosynthetic process from fatty acid&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/CHEBI_35366) and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_53387)</deletedAxiom>
<newAxiom>&apos;poly(hydroxyalkanoate) biosynthetic process from fatty acid&apos; SubClassOf &apos;fatty acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;poly(hydroxyalkanoate) biosynthetic process from fatty acid&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_53387) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_35366)</newAxiom>
<newAxiom>&apos;poly(hydroxyalkanoate) biosynthetic process from fatty acid&apos; SubClassOf &apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_35366</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042210</classIRI>
<classLabel>octamethylcyclotetrasiloxane catabolic process to dimethylsilanediol</classLabel>
<deletedAxiom>&apos;octamethylcyclotetrasiloxane catabolic process to dimethylsilanediol&apos; SubClassOf &apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_23816</deletedAxiom>
<deletedAxiom>&apos;octamethylcyclotetrasiloxane catabolic process to dimethylsilanediol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has output&apos; some http://purl.obolibrary.org/obo/CHEBI_23816) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_25640)</deletedAxiom>
<newAxiom>&apos;octamethylcyclotetrasiloxane catabolic process to dimethylsilanediol&apos; SubClassOf &apos;dimethylsilanediol metabolic process&apos;</newAxiom>
<newAxiom>&apos;octamethylcyclotetrasiloxane catabolic process to dimethylsilanediol&apos; SubClassOf &apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_23816</newAxiom>
<newAxiom>&apos;octamethylcyclotetrasiloxane catabolic process to dimethylsilanediol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some http://purl.obolibrary.org/obo/CHEBI_23816) and (&apos;has primary input&apos; some http://purl.obolibrary.org/obo/CHEBI_25640)</newAxiom>
</changedClass>
</changedClasses>
<newClasses>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>