<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
543
</numberChangedClasses>
<numberNewClasses>
124
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019265</classIRI>
<classLabel>glycine biosynthetic process, by transamination of glyoxylate</classLabel>
<deletedAxiom>&apos;glycine biosynthetic process, by transamination of glyoxylate&apos; SubClassOf &apos;has intermediate&apos; some &apos;glyoxylate&apos;</deletedAxiom>
<deletedAxiom>&apos;glycine biosynthetic process, by transamination of glyoxylate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;glyoxylate&apos;) and (&apos;has primary output&apos; some &apos;glycinate&apos;)</deletedAxiom>
<newAxiom>&apos;glycine biosynthetic process, by transamination of glyoxylate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;glyoxylate&apos;</newAxiom>
<newAxiom>&apos;glycine biosynthetic process, by transamination of glyoxylate&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;glyoxylate&apos;) and (&apos;has primary output&apos; some &apos;glycinate&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019273</classIRI>
<classLabel>L-alanine biosynthetic process via ornithine</classLabel>
<deletedAxiom>&apos;L-alanine biosynthetic process via ornithine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;ornithinate&apos;) and (&apos;has primary output&apos; some &apos;L-alaninate&apos;)</deletedAxiom>
<deletedAxiom>&apos;L-alanine biosynthetic process via ornithine&apos; SubClassOf &apos;has intermediate&apos; some &apos;ornithinate&apos;</deletedAxiom>
<newAxiom>&apos;L-alanine biosynthetic process via ornithine&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;ornithinate&apos;</newAxiom>
<newAxiom>&apos;L-alanine biosynthetic process via ornithine&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;ornithinate&apos;) and (&apos;has primary output&apos; some &apos;L-alaninate&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019279</classIRI>
<classLabel>L-methionine biosynthetic process from L-homoserine via cystathionine</classLabel>
<deletedAxiom>&apos;L-methionine biosynthetic process from L-homoserine via cystathionine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;cystathionine&apos;) and (&apos;has primary output&apos; some &apos;L-methionine&apos;) and (&apos;has primary input&apos; some &apos;L-homoserine&apos;)</deletedAxiom>
<deletedAxiom>&apos;L-methionine biosynthetic process from L-homoserine via cystathionine&apos; SubClassOf &apos;has intermediate&apos; some &apos;cystathionine&apos;</deletedAxiom>
<newAxiom>&apos;L-methionine biosynthetic process from L-homoserine via cystathionine&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;cystathionine&apos;</newAxiom>
<newAxiom>&apos;L-methionine biosynthetic process from L-homoserine via cystathionine&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;cystathionine&apos;) and (&apos;has primary output&apos; some &apos;L-methionine&apos;) and (&apos;has primary input&apos; some &apos;L-homoserine&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019287</classIRI>
<classLabel>isopentenyl diphosphate biosynthetic process, mevalonate pathway</classLabel>
<deletedAxiom>&apos;isopentenyl diphosphate biosynthetic process, mevalonate pathway&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;(R)-mevalonate&apos;) and (&apos;has primary output&apos; some &apos;isopentenyl diphosphate&apos;)</deletedAxiom>
<deletedAxiom>&apos;isopentenyl diphosphate biosynthetic process, mevalonate pathway&apos; SubClassOf &apos;has intermediate&apos; some &apos;(R)-mevalonate&apos;</deletedAxiom>
<newAxiom>&apos;isopentenyl diphosphate biosynthetic process, mevalonate pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;(R)-mevalonate&apos;</newAxiom>
<newAxiom>&apos;isopentenyl diphosphate biosynthetic process, mevalonate pathway&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;(R)-mevalonate&apos;) and (&apos;has primary output&apos; some &apos;isopentenyl diphosphate&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019288</classIRI>
<classLabel>isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway</classLabel>
<deletedAxiom>&apos;isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway&apos; SubClassOf &apos;has intermediate&apos; some &apos;1-deoxy-D-xylulose 5-phosphate&apos;</deletedAxiom>
<deletedAxiom>&apos;isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;1-deoxy-D-xylulose 5-phosphate&apos;) and (&apos;has primary output&apos; some &apos;isopentenyl diphosphate&apos;)</deletedAxiom>
<newAxiom>&apos;isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;1-deoxy-D-xylulose 5-phosphate&apos;) and (&apos;has primary output&apos; some &apos;isopentenyl diphosphate&apos;)</newAxiom>
<newAxiom>&apos;isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;1-deoxy-D-xylulose 5-phosphate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019292</classIRI>
<classLabel>tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate</classLabel>
<deletedAxiom>&apos;tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;3-(4-hydroxyphenyl)pyruvate&apos;) and (&apos;has primary output&apos; some &apos;tyrosine&apos;) and (&apos;has primary input&apos; some &apos;chorismate(2-)&apos;)</deletedAxiom>
<deletedAxiom>&apos;tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate&apos; SubClassOf &apos;has intermediate&apos; some &apos;3-(4-hydroxyphenyl)pyruvate&apos;</deletedAxiom>
<newAxiom>&apos;tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;3-(4-hydroxyphenyl)pyruvate&apos;</newAxiom>
<newAxiom>&apos;tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;3-(4-hydroxyphenyl)pyruvate&apos;) and (&apos;has primary output&apos; some &apos;tyrosine&apos;) and (&apos;has primary input&apos; some &apos;chorismate(2-)&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010812</classIRI>
<classLabel>negative regulation of cell-substrate adhesion</classLabel>
<deletedAxiom>&apos;negative regulation of cell-substrate adhesion&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;cell-substrate adhesion&apos;)</deletedAxiom>
<newAxiom>&apos;negative regulation of cell-substrate adhesion&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;cell-substrate adhesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010810</classIRI>
<classLabel>regulation of cell-substrate adhesion</classLabel>
<deletedAxiom>&apos;regulation of cell-substrate adhesion&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;cell-substrate adhesion&apos;)</deletedAxiom>
<newAxiom>&apos;regulation of cell-substrate adhesion&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;cell-substrate adhesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010811</classIRI>
<classLabel>positive regulation of cell-substrate adhesion</classLabel>
<deletedAxiom>&apos;positive regulation of cell-substrate adhesion&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;cell-substrate adhesion&apos;)</deletedAxiom>
<newAxiom>&apos;positive regulation of cell-substrate adhesion&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;cell-substrate adhesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009848</classIRI>
<classLabel>indoleacetic acid biosynthetic process via tryptophan</classLabel>
<deletedAxiom>&apos;indoleacetic acid biosynthetic process via tryptophan&apos; SubClassOf &apos;has intermediate&apos; some &apos;L-tryptophan&apos;</deletedAxiom>
<deletedAxiom>&apos;indoleacetic acid biosynthetic process via tryptophan&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;L-tryptophan&apos;) and (&apos;has primary output&apos; some &apos;indole-3-acetate&apos;)</deletedAxiom>
<newAxiom>&apos;indoleacetic acid biosynthetic process via tryptophan&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;L-tryptophan&apos;) and (&apos;has primary output&apos; some &apos;indole-3-acetate&apos;)</newAxiom>
<newAxiom>&apos;indoleacetic acid biosynthetic process via tryptophan&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;L-tryptophan&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009870</classIRI>
<classLabel>defense response signaling pathway, resistance gene-dependent</classLabel>
<newAxiom>&apos;defense response signaling pathway, resistance gene-dependent&apos; SubClassOf &apos;in taxon&apos; only &apos;Viridiplantae&apos;</newAxiom>
<newAxiom>&apos;defense response signaling pathway, resistance gene-dependent&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Viridiplantae&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019248</classIRI>
<classLabel>D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde</classLabel>
<deletedAxiom>&apos;D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde&apos; SubClassOf &apos;has intermediate&apos; some &apos;(R)-lactaldehyde&apos;</deletedAxiom>
<deletedAxiom>&apos;D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;(R)-lactaldehyde&apos;) and (&apos;starts with&apos; some &apos;methylglyoxal reductase (NADH-dependent) activity&apos;) and (&apos;ends with&apos; some &apos;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor&apos;) and (&apos;has primary output&apos; some &apos;(R)-lactate&apos;) and (&apos;has primary input&apos; some &apos;methylglyoxal&apos;)</deletedAxiom>
<newAxiom>&apos;D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;(R)-lactaldehyde&apos;</newAxiom>
<newAxiom>&apos;D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;starts with&apos; some &apos;methylglyoxal reductase (NADH-dependent) activity&apos;) and (&apos;ends with&apos; some &apos;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor&apos;) and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;(R)-lactaldehyde&apos;) and (&apos;has primary output&apos; some &apos;(R)-lactate&apos;) and (&apos;has primary input&apos; some &apos;methylglyoxal&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010706</classIRI>
<classLabel>ganglioside biosynthetic process via lactosylceramide</classLabel>
<deletedAxiom>&apos;ganglioside biosynthetic process via lactosylceramide&apos; SubClassOf &apos;has intermediate&apos; some &apos;beta-D-galactosyl-(1-4)-beta-D-glucosyl-(1-1)-N-acylsphingosine&apos;</deletedAxiom>
<deletedAxiom>&apos;ganglioside biosynthetic process via lactosylceramide&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;beta-D-galactosyl-(1-4)-beta-D-glucosyl-(1-1)-N-acylsphingosine&apos;) and (&apos;has primary output&apos; some &apos;ganglioside&apos;)</deletedAxiom>
<newAxiom>&apos;ganglioside biosynthetic process via lactosylceramide&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;beta-D-galactosyl-(1-4)-beta-D-glucosyl-(1-1)-N-acylsphingosine&apos;</newAxiom>
<newAxiom>&apos;ganglioside biosynthetic process via lactosylceramide&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;beta-D-galactosyl-(1-4)-beta-D-glucosyl-(1-1)-N-acylsphingosine&apos;) and (&apos;has primary output&apos; some &apos;ganglioside&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010707</classIRI>
<classLabel>globoside biosynthetic process via lactosylceramide</classLabel>
<deletedAxiom>&apos;globoside biosynthetic process via lactosylceramide&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;beta-D-galactosyl-(1-4)-beta-D-glucosyl-(1-1)-N-acylsphingosine&apos;) and (&apos;has primary output&apos; some &apos;globoside&apos;)</deletedAxiom>
<deletedAxiom>&apos;globoside biosynthetic process via lactosylceramide&apos; SubClassOf &apos;has intermediate&apos; some &apos;beta-D-galactosyl-(1-4)-beta-D-glucosyl-(1-1)-N-acylsphingosine&apos;</deletedAxiom>
<newAxiom>&apos;globoside biosynthetic process via lactosylceramide&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;beta-D-galactosyl-(1-4)-beta-D-glucosyl-(1-1)-N-acylsphingosine&apos;</newAxiom>
<newAxiom>&apos;globoside biosynthetic process via lactosylceramide&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;beta-D-galactosyl-(1-4)-beta-D-glucosyl-(1-1)-N-acylsphingosine&apos;) and (&apos;has primary output&apos; some &apos;globoside&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019093</classIRI>
<classLabel>mitochondrial RNA localization</classLabel>
<newAxiom>&apos;mitochondrial RNA localization&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;mitochondrial RNA localization&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009623</classIRI>
<classLabel>response to parasitic fungus</classLabel>
<deletedAxiom>&apos;response to parasitic fungus&apos; SubClassOf &apos;response to symbiotic fungus&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034643</classIRI>
<classLabel>establishment of mitochondrion localization, microtubule-mediated</classLabel>
<deletedAxiom>&apos;establishment of mitochondrion localization, microtubule-mediated&apos; EquivalentTo &apos;establishment of localization&apos; and (&apos;mediated_by&apos; some &apos;microtubule&apos;) and (&apos;transports or maintains localization of&apos; some &apos;mitochondrion&apos;)</deletedAxiom>
<newAxiom>&apos;establishment of mitochondrion localization, microtubule-mediated&apos; EquivalentTo &apos;establishment of localization&apos; and (&apos;transports or maintains localization of&apos; some &apos;mitochondrion&apos;) and (&apos;has causal agent&apos; some &apos;microtubule&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034551</classIRI>
<classLabel>mitochondrial respiratory chain complex III assembly</classLabel>
<newAxiom>&apos;mitochondrial respiratory chain complex III assembly&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;mitochondrial respiratory chain complex III assembly&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034553</classIRI>
<classLabel>mitochondrial respiratory chain complex II assembly</classLabel>
<newAxiom>&apos;mitochondrial respiratory chain complex II assembly&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;mitochondrial respiratory chain complex II assembly&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010497</classIRI>
<classLabel>plasmodesmata-mediated intercellular transport</classLabel>
<deletedAxiom>&apos;plasmodesmata-mediated intercellular transport&apos; SubClassOf &apos;mediated_by&apos; some &apos;plasmodesma&apos;</deletedAxiom>
<deletedAxiom>&apos;plasmodesmata-mediated intercellular transport&apos; EquivalentTo &apos;intercellular transport&apos; and (&apos;mediated_by&apos; some &apos;plasmodesma&apos;)</deletedAxiom>
<newAxiom>&apos;plasmodesmata-mediated intercellular transport&apos; EquivalentTo &apos;intercellular transport&apos; and (&apos;has causal agent&apos; some &apos;plasmodesma&apos;)</newAxiom>
<newAxiom>&apos;plasmodesmata-mediated intercellular transport&apos; SubClassOf &apos;has causal agent&apos; some &apos;plasmodesma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034498</classIRI>
<classLabel>early endosome to Golgi transport</classLabel>
<deletedAxiom>&apos;early endosome to Golgi transport&apos; EquivalentTo &apos;transport&apos; and (&apos;mediated_by&apos; some &apos;vesicle&apos;) and (&apos;has target start location&apos; some &apos;early endosome&apos;) and (&apos;has target end location&apos; some &apos;Golgi apparatus&apos;)</deletedAxiom>
<newAxiom>&apos;early endosome to Golgi transport&apos; EquivalentTo &apos;transport&apos; and (&apos;has target start location&apos; some &apos;early endosome&apos;) and (&apos;has target end location&apos; some &apos;Golgi apparatus&apos;) and (&apos;has causal agent&apos; some &apos;vesicle&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034499</classIRI>
<classLabel>late endosome to Golgi transport</classLabel>
<deletedAxiom>&apos;late endosome to Golgi transport&apos; EquivalentTo &apos;transport&apos; and (&apos;occurs in&apos; some &apos;cytoplasm&apos;) and (&apos;mediated_by&apos; some &apos;vesicle&apos;) and (&apos;has target start location&apos; some &apos;late endosome&apos;) and (&apos;has target end location&apos; some &apos;Golgi apparatus&apos;)</deletedAxiom>
<newAxiom>&apos;late endosome to Golgi transport&apos; EquivalentTo &apos;transport&apos; and (&apos;occurs in&apos; some &apos;cytoplasm&apos;) and (&apos;has target start location&apos; some &apos;late endosome&apos;) and (&apos;has target end location&apos; some &apos;Golgi apparatus&apos;) and (&apos;has causal agent&apos; some &apos;vesicle&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000965</classIRI>
<classLabel>mitochondrial RNA 3&apos;-end processing</classLabel>
<newAxiom>&apos;mitochondrial RNA 3&apos;-end processing&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000963</classIRI>
<classLabel>mitochondrial RNA processing</classLabel>
<newAxiom>&apos;mitochondrial RNA processing&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000964</classIRI>
<classLabel>mitochondrial RNA 5&apos;-end processing</classLabel>
<newAxiom>&apos;mitochondrial RNA 5&apos;-end processing&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000958</classIRI>
<classLabel>mitochondrial mRNA catabolic process</classLabel>
<newAxiom>&apos;mitochondrial mRNA catabolic process&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000959</classIRI>
<classLabel>mitochondrial RNA metabolic process</classLabel>
<newAxiom>&apos;mitochondrial RNA metabolic process&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;mitochondrial RNA metabolic process&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000957</classIRI>
<classLabel>mitochondrial RNA catabolic process</classLabel>
<newAxiom>&apos;mitochondrial RNA catabolic process&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034331</classIRI>
<classLabel>cell junction maintenance</classLabel>
<deletedAxiom>&apos;cell junction maintenance&apos; EquivalentTo &apos;cellular process&apos; and (&apos;results_in_maintenance_of&apos; some &apos;cell junction&apos;)</deletedAxiom>
<newAxiom>&apos;cell junction maintenance&apos; EquivalentTo &apos;cell junction organization&apos; and (&apos;results_in_maintenance_of&apos; some &apos;cell junction&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034332</classIRI>
<classLabel>adherens junction organization</classLabel>
<deletedAxiom>&apos;adherens junction organization&apos; SubClassOf &apos;cell junction organization&apos;</deletedAxiom>
<deletedAxiom>&apos;adherens junction organization&apos; EquivalentTo &apos;cellular component organization&apos; and (&apos;results_in_organization_of&apos; some &apos;adherens junction&apos;)</deletedAxiom>
<newAxiom>&apos;adherens junction organization&apos; EquivalentTo &apos;cell-cell junction organization&apos; and (&apos;results_in_organization_of&apos; some &apos;adherens junction&apos;)</newAxiom>
<newAxiom>&apos;adherens junction organization&apos; SubClassOf &apos;cell-cell junction organization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034333</classIRI>
<classLabel>adherens junction assembly</classLabel>
<deletedAxiom>&apos;adherens junction assembly&apos; SubClassOf &apos;cell junction assembly&apos;</deletedAxiom>
<newAxiom>&apos;adherens junction assembly&apos; SubClassOf &apos;cell-cell junction assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034334</classIRI>
<classLabel>adherens junction maintenance</classLabel>
<deletedAxiom>&apos;adherens junction maintenance&apos; EquivalentTo &apos;cellular process&apos; and (&apos;results_in_maintenance_of&apos; some &apos;adherens junction&apos;)</deletedAxiom>
<deletedAxiom>&apos;adherens junction maintenance&apos; SubClassOf &apos;cell junction maintenance&apos;</deletedAxiom>
<newAxiom>&apos;adherens junction maintenance&apos; SubClassOf &apos;cell-cell junction maintenance&apos;</newAxiom>
<newAxiom>&apos;adherens junction maintenance&apos; EquivalentTo &apos;cell-cell junction maintenance&apos; and (&apos;results_in_maintenance_of&apos; some &apos;adherens junction&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010204</classIRI>
<classLabel>defense response signaling pathway, resistance gene-independent</classLabel>
<newAxiom>&apos;defense response signaling pathway, resistance gene-independent&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Viridiplantae&apos;</newAxiom>
<newAxiom>&apos;defense response signaling pathway, resistance gene-independent&apos; SubClassOf &apos;in taxon&apos; only &apos;Viridiplantae&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010239</classIRI>
<classLabel>chloroplast mRNA processing</classLabel>
<newAxiom>&apos;chloroplast mRNA processing&apos; DisjointWith &apos;in taxon&apos; some &apos;Amoebozoa&apos;</newAxiom>
<newAxiom>&apos;chloroplast mRNA processing&apos; DisjointWith &apos;in taxon&apos; some &apos;Choanoflagellata&apos;</newAxiom>
<newAxiom>&apos;chloroplast mRNA processing&apos; DisjointWith &apos;in taxon&apos; some &apos;Fungi&apos;</newAxiom>
<newAxiom>&apos;chloroplast mRNA processing&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Choanoflagellata&apos;))</newAxiom>
<newAxiom>&apos;chloroplast mRNA processing&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Fungi&apos;))</newAxiom>
<newAxiom>&apos;chloroplast mRNA processing&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Amoebozoa&apos;))</newAxiom>
<newAxiom>&apos;chloroplast mRNA processing&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Metazoa&apos;))</newAxiom>
<newAxiom>&apos;chloroplast mRNA processing&apos; DisjointWith &apos;in taxon&apos; some &apos;Metazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009255</classIRI>
<classLabel>Entner-Doudoroff pathway through 6-phosphogluconate</classLabel>
<deletedAxiom>&apos;Entner-Doudoroff pathway through 6-phosphogluconate&apos; SubClassOf &apos;has intermediate&apos; some &apos;6-phospho-D-gluconate&apos;</deletedAxiom>
<deletedAxiom>&apos;Entner-Doudoroff pathway through 6-phosphogluconate&apos; EquivalentTo &apos;Entner-Doudoroff pathway&apos; and (&apos;has_part&apos; some &apos;phosphogluconate dehydratase activity&apos;) and (&apos;has intermediate&apos; some &apos;6-phospho-D-gluconate&apos;) and (&apos;ends with&apos; some &apos;2-dehydro-3-deoxy-phosphogluconate aldolase activity&apos;) and (&apos;has output&apos; some &apos;pyruvate&apos;) and (&apos;has output&apos; some &apos;glyceraldehyde 3-phosphate&apos;)</deletedAxiom>
<newAxiom>&apos;Entner-Doudoroff pathway through 6-phosphogluconate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;6-phospho-D-gluconate&apos;</newAxiom>
<newAxiom>&apos;Entner-Doudoroff pathway through 6-phosphogluconate&apos; EquivalentTo &apos;Entner-Doudoroff pathway&apos; and (&apos;has_part&apos; some &apos;phosphogluconate dehydratase activity&apos;) and (&apos;ends with&apos; some &apos;2-dehydro-3-deoxy-phosphogluconate aldolase activity&apos;) and (&apos;has output&apos; some &apos;pyruvate&apos;) and (&apos;has output&apos; some &apos;glyceraldehyde 3-phosphate&apos;) and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;6-phospho-D-gluconate&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010122</classIRI>
<classLabel>arginine catabolic process to alanine via ornithine</classLabel>
<deletedAxiom>&apos;arginine catabolic process to alanine via ornithine&apos; SubClassOf &apos;has intermediate&apos; some &apos;ornithinate&apos;</deletedAxiom>
<deletedAxiom>&apos;arginine catabolic process to alanine via ornithine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some &apos;ornithinate&apos;) and (&apos;has primary output&apos; some &apos;alaninate&apos;) and (&apos;has primary input&apos; some &apos;argininate&apos;)</deletedAxiom>
<newAxiom>&apos;arginine catabolic process to alanine via ornithine&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;ornithinate&apos;</newAxiom>
<newAxiom>&apos;arginine catabolic process to alanine via ornithine&apos; EquivalentTo &apos;catabolic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;ornithinate&apos;) and (&apos;has primary output&apos; some &apos;alaninate&apos;) and (&apos;has primary input&apos; some &apos;argininate&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010121</classIRI>
<classLabel>arginine catabolic process to proline via ornithine</classLabel>
<deletedAxiom>&apos;arginine catabolic process to proline via ornithine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some &apos;ornithinate&apos;) and (&apos;has primary output&apos; some &apos;prolinate&apos;) and (&apos;has primary input&apos; some &apos;argininate&apos;)</deletedAxiom>
<deletedAxiom>&apos;arginine catabolic process to proline via ornithine&apos; SubClassOf &apos;has intermediate&apos; some &apos;ornithinate&apos;</deletedAxiom>
<newAxiom>&apos;arginine catabolic process to proline via ornithine&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;ornithinate&apos;</newAxiom>
<newAxiom>&apos;arginine catabolic process to proline via ornithine&apos; EquivalentTo &apos;catabolic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;ornithinate&apos;) and (&apos;has primary output&apos; some &apos;prolinate&apos;) and (&apos;has primary input&apos; some &apos;argininate&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010142</classIRI>
<classLabel>farnesyl diphosphate biosynthetic process, mevalonate pathway</classLabel>
<deletedAxiom>&apos;farnesyl diphosphate biosynthetic process, mevalonate pathway&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;(R)-mevalonate&apos;) and (&apos;has primary output&apos; some &apos;farnesyl diphosphate&apos;)</deletedAxiom>
<deletedAxiom>&apos;farnesyl diphosphate biosynthetic process, mevalonate pathway&apos; SubClassOf &apos;has intermediate&apos; some &apos;(R)-mevalonate&apos;</deletedAxiom>
<newAxiom>&apos;farnesyl diphosphate biosynthetic process, mevalonate pathway&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;(R)-mevalonate&apos;) and (&apos;has primary output&apos; some &apos;farnesyl diphosphate&apos;)</newAxiom>
<newAxiom>&apos;farnesyl diphosphate biosynthetic process, mevalonate pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;(R)-mevalonate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048750</classIRI>
<classLabel>compound eye corneal lens morphogenesis</classLabel>
<newAxiom>&apos;compound eye corneal lens morphogenesis&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Arthropoda&apos;</newAxiom>
<newAxiom>&apos;compound eye corneal lens morphogenesis&apos; SubClassOf &apos;in taxon&apos; only &apos;Arthropoda&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097722</classIRI>
<classLabel>sperm motility</classLabel>
<newAxiom>&apos;sperm motility&apos; SubClassOf &apos;results in movement of&apos; some &apos;sperm&apos;</newAxiom>
<newAxiom>&apos;sperm motility&apos; EquivalentTo &apos;cell motility&apos; and (&apos;results in movement of&apos; some &apos;sperm&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097745</classIRI>
<classLabel>mitochondrial tRNA 5&apos;-end processing</classLabel>
<newAxiom>&apos;mitochondrial tRNA 5&apos;-end processing&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009089</classIRI>
<classLabel>lysine biosynthetic process via diaminopimelate</classLabel>
<deletedAxiom>&apos;lysine biosynthetic process via diaminopimelate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;2,6-diaminopimelate(2-)&apos;) and (&apos;has primary output&apos; some &apos;lysinate&apos;)</deletedAxiom>
<deletedAxiom>&apos;lysine biosynthetic process via diaminopimelate&apos; SubClassOf &apos;has intermediate&apos; some &apos;2,6-diaminopimelate(2-)&apos;</deletedAxiom>
<newAxiom>&apos;lysine biosynthetic process via diaminopimelate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;2,6-diaminopimelate(2-)&apos;</newAxiom>
<newAxiom>&apos;lysine biosynthetic process via diaminopimelate&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;2,6-diaminopimelate(2-)&apos;) and (&apos;has primary output&apos; some &apos;lysinate&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009095</classIRI>
<classLabel>aromatic amino acid family biosynthetic process, prephenate pathway</classLabel>
<deletedAxiom>&apos;aromatic amino acid family biosynthetic process, prephenate pathway&apos; SubClassOf &apos;has intermediate&apos; some &apos;prephenate(2-)&apos;</deletedAxiom>
<deletedAxiom>&apos;aromatic amino acid family biosynthetic process, prephenate pathway&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;prephenate(2-)&apos;) and (&apos;has primary output&apos; some &apos;aromatic amino acid&apos;)</deletedAxiom>
<newAxiom>&apos;aromatic amino acid family biosynthetic process, prephenate pathway&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;prephenate(2-)&apos;) and (&apos;has primary output&apos; some &apos;aromatic amino acid&apos;)</newAxiom>
<newAxiom>&apos;aromatic amino acid family biosynthetic process, prephenate pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;prephenate(2-)&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034054</classIRI>
<classLabel>negative regulation by symbiont of host defense-related programmed cell death</classLabel>
<deletedAxiom>&apos;negative regulation by symbiont of host defense-related programmed cell death&apos; SubClassOf &apos;negative regulation by symbiont of host defense response&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation by symbiont of host defense-related programmed cell death&apos; SubClassOf &apos;suppression of host defenses&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034055</classIRI>
<classLabel>positive regulation by symbiont of host defense-related programmed cell death</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host defense-related programmed cell death&apos; SubClassOf &apos;positive regulation by symbiont of host defense response&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation by symbiont of host defense-related programmed cell death&apos; SubClassOf &apos;induction by symbiont of host defense response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048502</classIRI>
<classLabel>ATPase-coupled thiamine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;ATPase-coupled thiamine transmembrane transporter activity&apos; SubClassOf &apos;ATPase-coupled transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;ATPase-coupled thiamine transmembrane transporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140394</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048522</classIRI>
<classLabel>positive regulation of cellular process</classLabel>
<deletedAxiom>&apos;positive regulation of cellular process&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;cellular process&apos;)</deletedAxiom>
<newAxiom>&apos;positive regulation of cellular process&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;cellular process&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000454</classIRI>
<classLabel>snoRNA guided rRNA pseudouridine synthesis</classLabel>
<deletedAxiom>&apos;snoRNA guided rRNA pseudouridine synthesis&apos; SubClassOf &apos;mediated_by&apos; some &apos;snoRNA&apos;</deletedAxiom>
<newAxiom>&apos;snoRNA guided rRNA pseudouridine synthesis&apos; SubClassOf &apos;has causal agent&apos; some &apos;snoRNA&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000452</classIRI>
<classLabel>snoRNA guided rRNA 2&apos;-O-methylation</classLabel>
<deletedAxiom>&apos;snoRNA guided rRNA 2&apos;-O-methylation&apos; SubClassOf &apos;mediated_by&apos; some &apos;snoRNA&apos;</deletedAxiom>
<newAxiom>&apos;snoRNA guided rRNA 2&apos;-O-methylation&apos; SubClassOf &apos;has causal agent&apos; some &apos;snoRNA&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097360</classIRI>
<classLabel>chorionic trophoblast cell proliferation</classLabel>
<newAxiom>&apos;chorionic trophoblast cell proliferation&apos; EquivalentTo &apos;cell population proliferation&apos; and (&apos;acts_on_population_of&apos; some &apos;chorionic trophoblast cell&apos;)</newAxiom>
<newAxiom>&apos;chorionic trophoblast cell proliferation&apos; SubClassOf &apos;acts_on_population_of&apos; some &apos;chorionic trophoblast cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097222</classIRI>
<classLabel>mitochondrial mRNA polyadenylation</classLabel>
<newAxiom>&apos;mitochondrial mRNA polyadenylation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097299</classIRI>
<classLabel>cysteine-type endopeptidase activity involved in plant-type hypersensitive response</classLabel>
<deletedAxiom>&apos;cysteine-type endopeptidase activity involved in plant-type hypersensitive response&apos; SubClassOf &apos;part of&apos; some &apos;plant-type hypersensitive response&apos;</deletedAxiom>
<deletedAxiom>&apos;cysteine-type endopeptidase activity involved in plant-type hypersensitive response&apos; SubClassOf &apos;cysteine-type endopeptidase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;cysteine-type endopeptidase activity involved in plant-type hypersensitive response&apos; EquivalentTo &apos;cysteine-type endopeptidase activity&apos; and (&apos;part of&apos; some &apos;plant-type hypersensitive response&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014714</classIRI>
<classLabel>myoblast fate commitment in head</classLabel>
<newAxiom>&apos;myoblast fate commitment in head&apos; SubClassOf &apos;in taxon&apos; only &apos;Bilateria&apos;</newAxiom>
<newAxiom>&apos;myoblast fate commitment in head&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Bilateria&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990126</classIRI>
<classLabel>retrograde transport, endosome to plasma membrane</classLabel>
<deletedAxiom>&apos;retrograde transport, endosome to plasma membrane&apos; EquivalentTo &apos;transport&apos; and (&apos;mediated_by&apos; some &apos;vesicle&apos;) and (&apos;has target start location&apos; some &apos;endosome&apos;) and (&apos;has target end location&apos; some &apos;plasma membrane&apos;)</deletedAxiom>
<newAxiom>&apos;retrograde transport, endosome to plasma membrane&apos; EquivalentTo &apos;transport&apos; and (&apos;has target start location&apos; some &apos;endosome&apos;) and (&apos;has target end location&apos; some &apos;plasma membrane&apos;) and (&apos;has causal agent&apos; some &apos;vesicle&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048041</classIRI>
<classLabel>focal adhesion assembly</classLabel>
<deletedAxiom>&apos;focal adhesion assembly&apos; SubClassOf &apos;cell-substrate adherens junction assembly&apos;</deletedAxiom>
<newAxiom>&apos;focal adhesion assembly&apos; SubClassOf &apos;cell-substrate junction assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048058</classIRI>
<classLabel>compound eye corneal lens development</classLabel>
<newAxiom>&apos;compound eye corneal lens development&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Arthropoda&apos;</newAxiom>
<newAxiom>&apos;compound eye corneal lens development&apos; SubClassOf &apos;in taxon&apos; only &apos;Arthropoda&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990180</classIRI>
<classLabel>mitochondrial tRNA 3&apos;-end processing</classLabel>
<newAxiom>&apos;mitochondrial tRNA 3&apos;-end processing&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000827</classIRI>
<classLabel>mitochondrial RNA surveillance</classLabel>
<newAxiom>&apos;mitochondrial RNA surveillance&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000803</classIRI>
<classLabel>endosomal signal transduction</classLabel>
<newAxiom>&apos;endosomal signal transduction&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;endosomal signal transduction&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990349</classIRI>
<classLabel>gap junction-mediated intercellular transport</classLabel>
<deletedAxiom>&apos;gap junction-mediated intercellular transport&apos; SubClassOf &apos;mediated_by&apos; some &apos;gap junction&apos;</deletedAxiom>
<deletedAxiom>&apos;gap junction-mediated intercellular transport&apos; EquivalentTo &apos;intercellular transport&apos; and (&apos;mediated_by&apos; some &apos;gap junction&apos;)</deletedAxiom>
<newAxiom>&apos;gap junction-mediated intercellular transport&apos; SubClassOf &apos;has causal agent&apos; some &apos;gap junction&apos;</newAxiom>
<newAxiom>&apos;gap junction-mediated intercellular transport&apos; EquivalentTo &apos;intercellular transport&apos; and (&apos;has causal agent&apos; some &apos;gap junction&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038202</classIRI>
<classLabel>TORC1 signaling</classLabel>
<deletedAxiom>&apos;TORC1 signaling&apos; EquivalentTo &apos;intracellular signal transduction&apos; and (&apos;mediated_by&apos; some &apos;TORC1 complex&apos;)</deletedAxiom>
<deletedAxiom>&apos;TORC1 signaling&apos; SubClassOf &apos;mediated_by&apos; some &apos;TORC1 complex&apos;</deletedAxiom>
<newAxiom>&apos;TORC1 signaling&apos; SubClassOf &apos;has causal agent&apos; some &apos;TORC1 complex&apos;</newAxiom>
<newAxiom>&apos;TORC1 signaling&apos; EquivalentTo &apos;intracellular signal transduction&apos; and (&apos;has causal agent&apos; some &apos;TORC1 complex&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038203</classIRI>
<classLabel>TORC2 signaling</classLabel>
<deletedAxiom>&apos;TORC2 signaling&apos; SubClassOf &apos;mediated_by&apos; some &apos;TORC2 complex&apos;</deletedAxiom>
<deletedAxiom>&apos;TORC2 signaling&apos; EquivalentTo &apos;intracellular signal transduction&apos; and (&apos;mediated_by&apos; some &apos;TORC2 complex&apos;)</deletedAxiom>
<newAxiom>&apos;TORC2 signaling&apos; EquivalentTo &apos;intracellular signal transduction&apos; and (&apos;has causal agent&apos; some &apos;TORC2 complex&apos;)</newAxiom>
<newAxiom>&apos;TORC2 signaling&apos; SubClassOf &apos;has causal agent&apos; some &apos;TORC2 complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905951</classIRI>
<classLabel>mitochondrion DNA recombination</classLabel>
<newAxiom>&apos;mitochondrion DNA recombination&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043947</classIRI>
<classLabel>positive regulation by host of symbiont catalytic activity</classLabel>
<deletedAxiom>&apos;positive regulation by host of symbiont catalytic activity&apos; SubClassOf &apos;negative regulation by host of symbiont molecular function&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043952</classIRI>
<classLabel>protein transport by the Sec complex</classLabel>
<deletedAxiom>&apos;protein transport by the Sec complex&apos; SubClassOf &apos;mediated_by&apos; some &apos;cell envelope Sec protein transport complex&apos;</deletedAxiom>
<newAxiom>&apos;protein transport by the Sec complex&apos; SubClassOf &apos;has causal agent&apos; some &apos;cell envelope Sec protein transport complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043953</classIRI>
<classLabel>protein transport by the Tat complex</classLabel>
<deletedAxiom>&apos;protein transport by the Tat complex&apos; SubClassOf &apos;mediated_by&apos; some &apos;TAT protein transport complex&apos;</deletedAxiom>
<deletedAxiom>&apos;protein transport by the Tat complex&apos; EquivalentTo &apos;transmembrane transport&apos; and (&apos;mediated_by&apos; some &apos;TAT protein transport complex&apos;) and (&apos;transports or maintains localization of&apos; some &apos;protein&apos;)</deletedAxiom>
<newAxiom>&apos;protein transport by the Tat complex&apos; EquivalentTo &apos;transmembrane transport&apos; and (&apos;transports or maintains localization of&apos; some &apos;protein&apos;) and (&apos;has causal agent&apos; some &apos;TAT protein transport complex&apos;)</newAxiom>
<newAxiom>&apos;protein transport by the Tat complex&apos; SubClassOf &apos;has causal agent&apos; some &apos;TAT protein transport complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018956</classIRI>
<classLabel>phenanthrene catabolic process via trans-9(R),10(R)-dihydrodiolphenanthrene</classLabel>
<deletedAxiom>&apos;phenanthrene catabolic process via trans-9(R),10(R)-dihydrodiolphenanthrene&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some &apos;(9R,10R)-9,10-dihydrophenanthrene-9,10-diol&apos;) and (&apos;has primary input&apos; some &apos;phenanthrene&apos;)</deletedAxiom>
<deletedAxiom>&apos;phenanthrene catabolic process via trans-9(R),10(R)-dihydrodiolphenanthrene&apos; SubClassOf &apos;has intermediate&apos; some &apos;(9R,10R)-9,10-dihydrophenanthrene-9,10-diol&apos;</deletedAxiom>
<newAxiom>&apos;phenanthrene catabolic process via trans-9(R),10(R)-dihydrodiolphenanthrene&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;(9R,10R)-9,10-dihydrophenanthrene-9,10-diol&apos;</newAxiom>
<newAxiom>&apos;phenanthrene catabolic process via trans-9(R),10(R)-dihydrodiolphenanthrene&apos; EquivalentTo &apos;catabolic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;(9R,10R)-9,10-dihydrophenanthrene-9,10-diol&apos;) and (&apos;has primary input&apos; some &apos;phenanthrene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018957</classIRI>
<classLabel>phenanthrene catabolic process via trans-9(S),10(S)-dihydrodiolphenanthrene</classLabel>
<deletedAxiom>&apos;phenanthrene catabolic process via trans-9(S),10(S)-dihydrodiolphenanthrene&apos; SubClassOf &apos;has intermediate&apos; some &apos;(9S,10S)-9,10-dihydrophenanthrene-9,10-diol&apos;</deletedAxiom>
<deletedAxiom>&apos;phenanthrene catabolic process via trans-9(S),10(S)-dihydrodiolphenanthrene&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some &apos;(9S,10S)-9,10-dihydrophenanthrene-9,10-diol&apos;) and (&apos;has primary input&apos; some &apos;phenanthrene&apos;)</deletedAxiom>
<newAxiom>&apos;phenanthrene catabolic process via trans-9(S),10(S)-dihydrodiolphenanthrene&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;(9S,10S)-9,10-dihydrophenanthrene-9,10-diol&apos;</newAxiom>
<newAxiom>&apos;phenanthrene catabolic process via trans-9(S),10(S)-dihydrodiolphenanthrene&apos; EquivalentTo &apos;catabolic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;(9S,10S)-9,10-dihydrophenanthrene-9,10-diol&apos;) and (&apos;has primary input&apos; some &apos;phenanthrene&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901259</classIRI>
<classLabel>chloroplast rRNA processing</classLabel>
<newAxiom>&apos;chloroplast rRNA processing&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Choanoflagellata&apos;))</newAxiom>
<newAxiom>&apos;chloroplast rRNA processing&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Amoebozoa&apos;))</newAxiom>
<newAxiom>&apos;chloroplast rRNA processing&apos; DisjointWith &apos;in taxon&apos; some &apos;Amoebozoa&apos;</newAxiom>
<newAxiom>&apos;chloroplast rRNA processing&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Fungi&apos;))</newAxiom>
<newAxiom>&apos;chloroplast rRNA processing&apos; DisjointWith &apos;in taxon&apos; some &apos;Choanoflagellata&apos;</newAxiom>
<newAxiom>&apos;chloroplast rRNA processing&apos; DisjointWith &apos;in taxon&apos; some &apos;Metazoa&apos;</newAxiom>
<newAxiom>&apos;chloroplast rRNA processing&apos; DisjointWith &apos;in taxon&apos; some &apos;Fungi&apos;</newAxiom>
<newAxiom>&apos;chloroplast rRNA processing&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Metazoa&apos;))</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901244</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter involved in defense response to fungus</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in defense response to fungus&apos; SubClassOf &apos;part of&apos; some &apos;defense response to fungus&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in defense response to fungus&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in defense response to fungus&apos; EquivalentTo &apos;positive regulation of transcription by RNA polymerase II&apos; and (&apos;part of&apos; some &apos;defense response to fungus&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901350</classIRI>
<classLabel>cell-cell signaling involved in cell-cell junction organization</classLabel>
<deletedAxiom>&apos;cell-cell signaling involved in cell-cell junction organization&apos; SubClassOf &apos;part of&apos; some &apos;cell-cell junction organization&apos;</deletedAxiom>
<deletedAxiom>&apos;cell-cell signaling involved in cell-cell junction organization&apos; SubClassOf &apos;cell-cell signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;cell-cell signaling involved in cell-cell junction organization&apos; EquivalentTo &apos;cell-cell signaling&apos; and (&apos;part of&apos; some &apos;cell-cell junction organization&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901504</classIRI>
<classLabel>triazole transport</classLabel>
<deletedAxiom>&apos;triazole transport&apos; SubClassOf &apos;azole transport&apos;</deletedAxiom>
<newAxiom>&apos;triazole transport&apos; SubClassOf &apos;nitrogen compound transport&apos;</newAxiom>
<newAxiom>&apos;triazole transport&apos; SubClassOf &apos;organic substance transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043504</classIRI>
<classLabel>mitochondrial DNA repair</classLabel>
<newAxiom>&apos;mitochondrial DNA repair&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018400</classIRI>
<classLabel>peptidyl-proline hydroxylation to 3-hydroxy-L-proline</classLabel>
<deletedAxiom>&apos;peptidyl-proline hydroxylation to 3-hydroxy-L-proline&apos; SubClassOf &apos;cellular modified amino acid metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018401</classIRI>
<classLabel>peptidyl-proline hydroxylation to 4-hydroxy-L-proline</classLabel>
<deletedAxiom>&apos;peptidyl-proline hydroxylation to 4-hydroxy-L-proline&apos; SubClassOf &apos;cellular modified amino acid metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043390</classIRI>
<classLabel>aflatoxin B1 metabolic process</classLabel>
<deletedAxiom>&apos;aflatoxin B1 metabolic process&apos; SubClassOf &apos;cellular ketone metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;aflatoxin B1 metabolic process&apos; SubClassOf &apos;cellular aromatic compound metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;aflatoxin B1 metabolic process&apos; SubClassOf &apos;has primary input or output&apos; some &apos;aflatoxin B1&apos;</deletedAxiom>
<deletedAxiom>&apos;aflatoxin B1 metabolic process&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has primary input or output&apos; some &apos;aflatoxin B1&apos;)</deletedAxiom>
<deletedAxiom>&apos;aflatoxin B1 metabolic process&apos; SubClassOf &apos;ether metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;aflatoxin B1 metabolic process&apos; SubClassOf &apos;aflatoxin metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043391</classIRI>
<classLabel>aflatoxin B2 metabolic process</classLabel>
<deletedAxiom>&apos;aflatoxin B2 metabolic process&apos; SubClassOf &apos;has primary input or output&apos; some &apos;aflatoxin B2&apos;</deletedAxiom>
<deletedAxiom>&apos;aflatoxin B2 metabolic process&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has primary input or output&apos; some &apos;aflatoxin B2&apos;)</deletedAxiom>
<deletedAxiom>&apos;aflatoxin B2 metabolic process&apos; SubClassOf &apos;aflatoxin metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901890</classIRI>
<classLabel>positive regulation of cell junction assembly</classLabel>
<deletedAxiom>&apos;positive regulation of cell junction assembly&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;cell junction assembly&apos;)</deletedAxiom>
<newAxiom>&apos;positive regulation of cell junction assembly&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;cell junction assembly&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901888</classIRI>
<classLabel>regulation of cell junction assembly</classLabel>
<deletedAxiom>&apos;regulation of cell junction assembly&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;cell junction assembly&apos;)</deletedAxiom>
<newAxiom>&apos;regulation of cell junction assembly&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;cell junction assembly&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901889</classIRI>
<classLabel>negative regulation of cell junction assembly</classLabel>
<deletedAxiom>&apos;negative regulation of cell junction assembly&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;cell junction assembly&apos;)</deletedAxiom>
<newAxiom>&apos;negative regulation of cell junction assembly&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;cell junction assembly&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018396</classIRI>
<classLabel>peptidyl-lysine hydroxylation to 4-hydroxy-L-lysine</classLabel>
<deletedAxiom>&apos;peptidyl-lysine hydroxylation to 4-hydroxy-L-lysine&apos; SubClassOf &apos;cellular modified amino acid metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018397</classIRI>
<classLabel>peptidyl-phenylalanine bromination to L-2&apos;-bromophenylalanine</classLabel>
<deletedAxiom>&apos;peptidyl-phenylalanine bromination to L-2&apos;-bromophenylalanine&apos; SubClassOf &apos;cellular modified amino acid metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018398</classIRI>
<classLabel>peptidyl-phenylalanine bromination to L-3&apos;-bromophenylalanine</classLabel>
<deletedAxiom>&apos;peptidyl-phenylalanine bromination to L-3&apos;-bromophenylalanine&apos; SubClassOf &apos;cellular modified amino acid metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018399</classIRI>
<classLabel>peptidyl-phenylalanine bromination to L-4&apos;-bromophenylalanine</classLabel>
<deletedAxiom>&apos;peptidyl-phenylalanine bromination to L-4&apos;-bromophenylalanine&apos; SubClassOf &apos;cellular modified amino acid metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018265</classIRI>
<classLabel>GPI anchor biosynthetic process via N-asparaginyl-glycosylphosphatidylinositolethanolamine</classLabel>
<deletedAxiom>&apos;GPI anchor biosynthetic process via N-asparaginyl-glycosylphosphatidylinositolethanolamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;N-asparaginyl-glycosylphosphatidylinositolethanolamine&apos;) and (&apos;has primary output&apos; some &apos;glycosylphosphatidylinositol&apos;)</deletedAxiom>
<deletedAxiom>&apos;GPI anchor biosynthetic process via N-asparaginyl-glycosylphosphatidylinositolethanolamine&apos; SubClassOf &apos;has intermediate&apos; some &apos;N-asparaginyl-glycosylphosphatidylinositolethanolamine&apos;</deletedAxiom>
<newAxiom>&apos;GPI anchor biosynthetic process via N-asparaginyl-glycosylphosphatidylinositolethanolamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;N-asparaginyl-glycosylphosphatidylinositolethanolamine&apos;) and (&apos;has primary output&apos; some &apos;glycosylphosphatidylinositol&apos;)</newAxiom>
<newAxiom>&apos;GPI anchor biosynthetic process via N-asparaginyl-glycosylphosphatidylinositolethanolamine&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;N-asparaginyl-glycosylphosphatidylinositolethanolamine&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018266</classIRI>
<classLabel>GPI anchor biosynthetic process via N-aspartyl-glycosylphosphatidylinositolethanolamine</classLabel>
<deletedAxiom>&apos;GPI anchor biosynthetic process via N-aspartyl-glycosylphosphatidylinositolethanolamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;N-aspartyl-glycosylphosphatidylinositolethanolamine&apos;) and (&apos;has primary output&apos; some &apos;glycosylphosphatidylinositol&apos;)</deletedAxiom>
<deletedAxiom>&apos;GPI anchor biosynthetic process via N-aspartyl-glycosylphosphatidylinositolethanolamine&apos; SubClassOf &apos;has intermediate&apos; some &apos;N-aspartyl-glycosylphosphatidylinositolethanolamine&apos;</deletedAxiom>
<newAxiom>&apos;GPI anchor biosynthetic process via N-aspartyl-glycosylphosphatidylinositolethanolamine&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;N-aspartyl-glycosylphosphatidylinositolethanolamine&apos;</newAxiom>
<newAxiom>&apos;GPI anchor biosynthetic process via N-aspartyl-glycosylphosphatidylinositolethanolamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;N-aspartyl-glycosylphosphatidylinositolethanolamine&apos;) and (&apos;has primary output&apos; some &apos;glycosylphosphatidylinositol&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018267</classIRI>
<classLabel>GPI anchor biosynthetic process via N-cysteinyl-glycosylphosphatidylinositolethanolamine</classLabel>
<deletedAxiom>&apos;GPI anchor biosynthetic process via N-cysteinyl-glycosylphosphatidylinositolethanolamine&apos; SubClassOf &apos;has intermediate&apos; some &apos;N-cysteinyl-glycosylphosphatidylinositolethanolamine&apos;</deletedAxiom>
<deletedAxiom>&apos;GPI anchor biosynthetic process via N-cysteinyl-glycosylphosphatidylinositolethanolamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;N-cysteinyl-glycosylphosphatidylinositolethanolamine&apos;) and (&apos;has primary output&apos; some &apos;glycosylphosphatidylinositol&apos;)</deletedAxiom>
<newAxiom>&apos;GPI anchor biosynthetic process via N-cysteinyl-glycosylphosphatidylinositolethanolamine&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;N-cysteinyl-glycosylphosphatidylinositolethanolamine&apos;</newAxiom>
<newAxiom>&apos;GPI anchor biosynthetic process via N-cysteinyl-glycosylphosphatidylinositolethanolamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;N-cysteinyl-glycosylphosphatidylinositolethanolamine&apos;) and (&apos;has primary output&apos; some &apos;glycosylphosphatidylinositol&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018268</classIRI>
<classLabel>GPI anchor biosynthetic process via N-glycyl-glycosylphosphatidylinositolethanolamine</classLabel>
<deletedAxiom>&apos;GPI anchor biosynthetic process via N-glycyl-glycosylphosphatidylinositolethanolamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;N-glycyl-glycosylphosphatidylinositolethanolamine&apos;) and (&apos;has primary output&apos; some &apos;glycosylphosphatidylinositol&apos;)</deletedAxiom>
<deletedAxiom>&apos;GPI anchor biosynthetic process via N-glycyl-glycosylphosphatidylinositolethanolamine&apos; SubClassOf &apos;has intermediate&apos; some &apos;N-glycyl-glycosylphosphatidylinositolethanolamine&apos;</deletedAxiom>
<newAxiom>&apos;GPI anchor biosynthetic process via N-glycyl-glycosylphosphatidylinositolethanolamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;N-glycyl-glycosylphosphatidylinositolethanolamine&apos;) and (&apos;has primary output&apos; some &apos;glycosylphosphatidylinositol&apos;)</newAxiom>
<newAxiom>&apos;GPI anchor biosynthetic process via N-glycyl-glycosylphosphatidylinositolethanolamine&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;N-glycyl-glycosylphosphatidylinositolethanolamine&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018269</classIRI>
<classLabel>GPI anchor biosynthetic process via N-seryl-glycosylphosphatidylinositolethanolamine</classLabel>
<deletedAxiom>&apos;GPI anchor biosynthetic process via N-seryl-glycosylphosphatidylinositolethanolamine&apos; SubClassOf &apos;has intermediate&apos; some &apos;N-seryl-glycosylphosphatidylinositolethanolamine&apos;</deletedAxiom>
<deletedAxiom>&apos;GPI anchor biosynthetic process via N-seryl-glycosylphosphatidylinositolethanolamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;N-seryl-glycosylphosphatidylinositolethanolamine&apos;) and (&apos;has primary output&apos; some &apos;glycosylphosphatidylinositol&apos;)</deletedAxiom>
<newAxiom>&apos;GPI anchor biosynthetic process via N-seryl-glycosylphosphatidylinositolethanolamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;N-seryl-glycosylphosphatidylinositolethanolamine&apos;) and (&apos;has primary output&apos; some &apos;glycosylphosphatidylinositol&apos;)</newAxiom>
<newAxiom>&apos;GPI anchor biosynthetic process via N-seryl-glycosylphosphatidylinositolethanolamine&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;N-seryl-glycosylphosphatidylinositolethanolamine&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018270</classIRI>
<classLabel>GPI anchor biosynthetic process via N-alanyl-glycosylphosphatidylinositolethanolamine</classLabel>
<deletedAxiom>&apos;GPI anchor biosynthetic process via N-alanyl-glycosylphosphatidylinositolethanolamine&apos; SubClassOf &apos;has intermediate&apos; some &apos;N-alanyl-glycosylphosphatidylinositolethanolamine&apos;</deletedAxiom>
<deletedAxiom>&apos;GPI anchor biosynthetic process via N-alanyl-glycosylphosphatidylinositolethanolamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;N-alanyl-glycosylphosphatidylinositolethanolamine&apos;) and (&apos;has primary output&apos; some &apos;glycosylphosphatidylinositol&apos;)</deletedAxiom>
<newAxiom>&apos;GPI anchor biosynthetic process via N-alanyl-glycosylphosphatidylinositolethanolamine&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;N-alanyl-glycosylphosphatidylinositolethanolamine&apos;</newAxiom>
<newAxiom>&apos;GPI anchor biosynthetic process via N-alanyl-glycosylphosphatidylinositolethanolamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;N-alanyl-glycosylphosphatidylinositolethanolamine&apos;) and (&apos;has primary output&apos; some &apos;glycosylphosphatidylinositol&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033693</classIRI>
<classLabel>neurofilament bundle assembly</classLabel>
<newAxiom>&apos;neurofilament bundle assembly&apos; SubClassOf &apos;in taxon&apos; only &apos;Metazoa&apos;</newAxiom>
<newAxiom>&apos;neurofilament bundle assembly&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Metazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043001</classIRI>
<classLabel>Golgi to plasma membrane protein transport</classLabel>
<deletedAxiom>&apos;Golgi to plasma membrane protein transport&apos; EquivalentTo &apos;protein transport&apos; and (&apos;mediated_by&apos; some &apos;vesicle&apos;) and (&apos;has target start location&apos; some &apos;Golgi apparatus&apos;) and (&apos;has target end location&apos; some &apos;plasma membrane&apos;)</deletedAxiom>
<newAxiom>&apos;Golgi to plasma membrane protein transport&apos; EquivalentTo &apos;protein transport&apos; and (&apos;has target start location&apos; some &apos;Golgi apparatus&apos;) and (&apos;has target end location&apos; some &apos;plasma membrane&apos;) and (&apos;has causal agent&apos; some &apos;vesicle&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033617</classIRI>
<classLabel>mitochondrial respiratory chain complex IV assembly</classLabel>
<newAxiom>&apos;mitochondrial respiratory chain complex IV assembly&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;mitochondrial respiratory chain complex IV assembly&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033615</classIRI>
<classLabel>mitochondrial proton-transporting ATP synthase complex assembly</classLabel>
<newAxiom>&apos;mitochondrial proton-transporting ATP synthase complex assembly&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;mitochondrial proton-transporting ATP synthase complex assembly&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033660</classIRI>
<classLabel>negative regulation by symbiont of host resistance gene-dependent defense response</classLabel>
<deletedAxiom>&apos;negative regulation by symbiont of host resistance gene-dependent defense response&apos; SubClassOf &apos;negative regulation by symbiont of host defense response&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation by symbiont of host resistance gene-dependent defense response&apos; SubClassOf &apos;suppression of host defenses&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033661</classIRI>
<classLabel>negative regulation by symbiont of defense-related host reactive oxygen species production</classLabel>
<deletedAxiom>&apos;negative regulation by symbiont of defense-related host reactive oxygen species production&apos; SubClassOf &apos;negative regulation by symbiont of host defense response&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation by symbiont of defense-related host reactive oxygen species production&apos; SubClassOf &apos;suppression of host defenses&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033664</classIRI>
<classLabel>positive regulation by symbiont of host defense-related protein level</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host defense-related protein level&apos; SubClassOf &apos;positive regulation by symbiont of host defense response&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation by symbiont of host defense-related protein level&apos; SubClassOf &apos;induction by symbiont of host defense response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033663</classIRI>
<classLabel>negative regulation by symbiont of host defense-related protein level</classLabel>
<deletedAxiom>&apos;negative regulation by symbiont of host defense-related protein level&apos; SubClassOf &apos;negative regulation by symbiont of host defense response&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation by symbiont of host defense-related protein level&apos; SubClassOf &apos;suppression of host defenses&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070576</classIRI>
<classLabel>vitamin D 24-hydroxylase activity</classLabel>
<deletedAxiom>&apos;vitamin D 24-hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity&apos;</deletedAxiom>
<newAxiom>&apos;vitamin D 24-hydroxylase activity&apos; SubClassOf &apos;monooxygenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070560</classIRI>
<classLabel>protein secretion by platelet</classLabel>
<deletedAxiom>&apos;protein secretion by platelet&apos; EquivalentTo &apos;protein secretion&apos; and (&apos;mediated_by&apos; some &apos;platelet&apos;)</deletedAxiom>
<deletedAxiom>&apos;protein secretion by platelet&apos; SubClassOf &apos;mediated_by&apos; some &apos;platelet&apos;</deletedAxiom>
<newAxiom>&apos;protein secretion by platelet&apos; SubClassOf &apos;has causal agent&apos; some &apos;platelet&apos;</newAxiom>
<newAxiom>&apos;protein secretion by platelet&apos; EquivalentTo &apos;protein secretion&apos; and (&apos;has causal agent&apos; some &apos;platelet&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0021535</classIRI>
<classLabel>cell migration in hindbrain</classLabel>
<newAxiom>&apos;cell migration in hindbrain&apos; SubClassOf &apos;in taxon&apos; only &apos;Craniata chordates&apos;</newAxiom>
<newAxiom>&apos;cell migration in hindbrain&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Craniata chordates&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0021533</classIRI>
<classLabel>cell differentiation in hindbrain</classLabel>
<newAxiom>&apos;cell differentiation in hindbrain&apos; SubClassOf &apos;in taxon&apos; only &apos;Craniata chordates&apos;</newAxiom>
<newAxiom>&apos;cell differentiation in hindbrain&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Craniata chordates&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0021534</classIRI>
<classLabel>cell proliferation in hindbrain</classLabel>
<newAxiom>&apos;cell proliferation in hindbrain&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Craniata chordates&apos;</newAxiom>
<newAxiom>&apos;cell proliferation in hindbrain&apos; SubClassOf &apos;in taxon&apos; only &apos;Craniata chordates&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045324</classIRI>
<classLabel>late endosome to vacuole transport</classLabel>
<deletedAxiom>&apos;late endosome to vacuole transport&apos; EquivalentTo &apos;intracellular transport&apos; and (&apos;mediated_by&apos; some &apos;vesicle&apos;) and (&apos;has target start location&apos; some &apos;late endosome&apos;) and (&apos;has target end location&apos; some &apos;vacuole&apos;)</deletedAxiom>
<newAxiom>&apos;late endosome to vacuole transport&apos; EquivalentTo &apos;intracellular transport&apos; and (&apos;has target start location&apos; some &apos;late endosome&apos;) and (&apos;has target end location&apos; some &apos;vacuole&apos;) and (&apos;has causal agent&apos; some &apos;vesicle&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035921</classIRI>
<classLabel>desmosome disassembly</classLabel>
<deletedAxiom>&apos;desmosome disassembly&apos; SubClassOf &apos;cellular component disassembly&apos;</deletedAxiom>
<newAxiom>&apos;desmosome disassembly&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0150147</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045216</classIRI>
<classLabel>cell-cell junction organization</classLabel>
<deletedAxiom>&apos;cell-cell junction organization&apos; EquivalentTo &apos;cellular component organization&apos; and (&apos;results_in_organization_of&apos; some &apos;cell-cell junction&apos;)</deletedAxiom>
<newAxiom>&apos;cell-cell junction organization&apos; EquivalentTo &apos;cell junction organization&apos; and (&apos;results_in_organization_of&apos; some &apos;cell-cell junction&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045217</classIRI>
<classLabel>cell-cell junction maintenance</classLabel>
<deletedAxiom>&apos;cell-cell junction maintenance&apos; EquivalentTo &apos;cellular process&apos; and (&apos;results_in_maintenance_of&apos; some &apos;cell-cell junction&apos;)</deletedAxiom>
<newAxiom>&apos;cell-cell junction maintenance&apos; EquivalentTo &apos;cell junction organization&apos; and (&apos;results_in_maintenance_of&apos; some &apos;cell-cell junction&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045218</classIRI>
<classLabel>zonula adherens maintenance</classLabel>
<deletedAxiom>&apos;zonula adherens maintenance&apos; SubClassOf &apos;cell-cell junction maintenance&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070183</classIRI>
<classLabel>mitochondrial tryptophanyl-tRNA aminoacylation</classLabel>
<newAxiom>&apos;mitochondrial tryptophanyl-tRNA aminoacylation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070184</classIRI>
<classLabel>mitochondrial tyrosyl-tRNA aminoacylation</classLabel>
<newAxiom>&apos;mitochondrial tyrosyl-tRNA aminoacylation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070185</classIRI>
<classLabel>mitochondrial valyl-tRNA aminoacylation</classLabel>
<newAxiom>&apos;mitochondrial valyl-tRNA aminoacylation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035745</classIRI>
<classLabel>T-helper 2 cell cytokine production</classLabel>
<deletedAxiom>&apos;T-helper 2 cell cytokine production&apos; EquivalentTo &apos;cytokine production&apos; and (&apos;mediated_by&apos; some &apos;T-helper 2 cell&apos;)</deletedAxiom>
<deletedAxiom>&apos;T-helper 2 cell cytokine production&apos; SubClassOf &apos;mediated_by&apos; some &apos;T-helper 2 cell&apos;</deletedAxiom>
<newAxiom>&apos;T-helper 2 cell cytokine production&apos; SubClassOf &apos;has causal agent&apos; some &apos;T-helper 2 cell&apos;</newAxiom>
<newAxiom>&apos;T-helper 2 cell cytokine production&apos; EquivalentTo &apos;cytokine production&apos; and (&apos;has causal agent&apos; some &apos;T-helper 2 cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035743</classIRI>
<classLabel>CD4-positive, alpha-beta T cell cytokine production</classLabel>
<deletedAxiom>&apos;CD4-positive, alpha-beta T cell cytokine production&apos; EquivalentTo &apos;cytokine production&apos; and (&apos;mediated_by&apos; some &apos;CD4-positive, alpha-beta T cell&apos;)</deletedAxiom>
<deletedAxiom>&apos;CD4-positive, alpha-beta T cell cytokine production&apos; SubClassOf &apos;mediated_by&apos; some &apos;CD4-positive, alpha-beta T cell&apos;</deletedAxiom>
<newAxiom>&apos;CD4-positive, alpha-beta T cell cytokine production&apos; SubClassOf &apos;has causal agent&apos; some &apos;CD4-positive, alpha-beta T cell&apos;</newAxiom>
<newAxiom>&apos;CD4-positive, alpha-beta T cell cytokine production&apos; EquivalentTo &apos;cytokine production&apos; and (&apos;has causal agent&apos; some &apos;CD4-positive, alpha-beta T cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035744</classIRI>
<classLabel>T-helper 1 cell cytokine production</classLabel>
<deletedAxiom>&apos;T-helper 1 cell cytokine production&apos; SubClassOf &apos;mediated_by&apos; some &apos;T-helper 1 cell&apos;</deletedAxiom>
<deletedAxiom>&apos;T-helper 1 cell cytokine production&apos; EquivalentTo &apos;cytokine production&apos; and (&apos;mediated_by&apos; some &apos;T-helper 1 cell&apos;)</deletedAxiom>
<newAxiom>&apos;T-helper 1 cell cytokine production&apos; EquivalentTo &apos;cytokine production&apos; and (&apos;has causal agent&apos; some &apos;T-helper 1 cell&apos;)</newAxiom>
<newAxiom>&apos;T-helper 1 cell cytokine production&apos; SubClassOf &apos;has causal agent&apos; some &apos;T-helper 1 cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045122</classIRI>
<classLabel>aflatoxin biosynthetic process</classLabel>
<deletedAxiom>&apos;aflatoxin biosynthetic process&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some &apos;aflatoxin&apos;)</deletedAxiom>
<newAxiom>&apos;aflatoxin biosynthetic process&apos; SubClassOf &apos;has primary input&apos; some &apos;acetate&apos;</newAxiom>
<newAxiom>&apos;aflatoxin biosynthetic process&apos; SubClassOf &apos;has_part&apos; some &apos;versicolorin reductase activity&apos;</newAxiom>
<newAxiom>&apos;aflatoxin biosynthetic process&apos; SubClassOf &apos;has_part&apos; some &apos;sterigmatocystin 7-O-methyltransferase activity&apos;</newAxiom>
<newAxiom>&apos;aflatoxin biosynthetic process&apos; SubClassOf &apos;has_part&apos; some http://purl.obolibrary.org/obo/GO_0140397</newAxiom>
<newAxiom>&apos;aflatoxin biosynthetic process&apos; SubClassOf &apos;has_part&apos; some http://purl.obolibrary.org/obo/GO_0140398</newAxiom>
<newAxiom>&apos;aflatoxin biosynthetic process&apos; SubClassOf &apos;has_part&apos; some http://purl.obolibrary.org/obo/GO_0140395</newAxiom>
<newAxiom>&apos;aflatoxin biosynthetic process&apos; SubClassOf &apos;has_part&apos; some &apos;demethylsterigmatocystin 6-O-methyltransferase activity&apos;</newAxiom>
<newAxiom>&apos;aflatoxin biosynthetic process&apos; SubClassOf &apos;has_part&apos; some http://purl.obolibrary.org/obo/GO_0140396</newAxiom>
<newAxiom>&apos;aflatoxin biosynthetic process&apos; SubClassOf &apos;has_part&apos; some &apos;versicolorin B synthase activity&apos;</newAxiom>
<newAxiom>&apos;aflatoxin biosynthetic process&apos; SubClassOf &apos;has_part&apos; some http://purl.obolibrary.org/obo/GO_0140393</newAxiom>
<newAxiom>&apos;aflatoxin biosynthetic process&apos; SubClassOf &apos;acetate metabolic process&apos;</newAxiom>
<newAxiom>&apos;aflatoxin biosynthetic process&apos; SubClassOf &apos;ends with&apos; some http://purl.obolibrary.org/obo/GO_0140399</newAxiom>
<newAxiom>&apos;aflatoxin biosynthetic process&apos; SubClassOf &apos;has_part&apos; some &apos;norsolorinate anthrone synthase activity&apos;</newAxiom>
<newAxiom>&apos;aflatoxin biosynthetic process&apos; SubClassOf &apos;starts with&apos; some &apos;fatty-acyl-CoA synthase activity&apos;</newAxiom>
<newAxiom>&apos;aflatoxin biosynthetic process&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has_part&apos; some &apos;oxidoreductase activity&apos;) and (&apos;has_part&apos; some &apos;versicolorin reductase activity&apos;) and (&apos;has_part&apos; some &apos;versicolorin B synthase activity&apos;) and (&apos;has_part&apos; some &apos;demethylsterigmatocystin 6-O-methyltransferase activity&apos;) and (&apos;has_part&apos; some &apos;sterigmatocystin 7-O-methyltransferase activity&apos;) and (&apos;has_part&apos; some &apos;norsolorinate anthrone synthase activity&apos;) and (&apos;has_part&apos; some http://purl.obolibrary.org/obo/GO_0140393) and (&apos;has_part&apos; some http://purl.obolibrary.org/obo/GO_0140395) and (&apos;has_part&apos; some http://purl.obolibrary.org/obo/GO_0140396) and (&apos;has_part&apos; some http://purl.obolibrary.org/obo/GO_0140397) and (&apos;has_part&apos; some http://purl.obolibrary.org/obo/GO_0140398) and (&apos;starts with&apos; some &apos;fatty-acyl-CoA synthase activity&apos;) and (&apos;ends with&apos; some http://purl.obolibrary.org/obo/GO_0140399) and (&apos;has primary output&apos; some &apos;aflatoxin&apos;) and (&apos;has primary input&apos; some &apos;acetate&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045117</classIRI>
<classLabel>azole transport</classLabel>
<deletedAxiom>&apos;azole transport&apos; EquivalentTo &apos;transport&apos; and (&apos;transports or maintains localization of&apos; some &apos;azole&apos;)</deletedAxiom>
<newAxiom>&apos;azole transport&apos; EquivalentTo &apos;transport&apos; and (&apos;transports or maintains localization of&apos; some &apos;azole&apos;) and (&apos;results in transport across&apos; some &apos;membrane&apos;)</newAxiom>
<newAxiom>&apos;azole transport&apos; SubClassOf &apos;transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070153</classIRI>
<classLabel>mitochondrial leucyl-tRNA aminoacylation</classLabel>
<newAxiom>&apos;mitochondrial leucyl-tRNA aminoacylation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070154</classIRI>
<classLabel>mitochondrial lysyl-tRNA aminoacylation</classLabel>
<newAxiom>&apos;mitochondrial lysyl-tRNA aminoacylation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070155</classIRI>
<classLabel>mitochondrial methionyl-tRNA aminoacylation</classLabel>
<newAxiom>&apos;mitochondrial methionyl-tRNA aminoacylation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070156</classIRI>
<classLabel>mitochondrial phenylalanyl-tRNA aminoacylation</classLabel>
<newAxiom>&apos;mitochondrial phenylalanyl-tRNA aminoacylation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070157</classIRI>
<classLabel>mitochondrial prolyl-tRNA aminoacylation</classLabel>
<newAxiom>&apos;mitochondrial prolyl-tRNA aminoacylation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070158</classIRI>
<classLabel>mitochondrial seryl-tRNA aminoacylation</classLabel>
<newAxiom>&apos;mitochondrial seryl-tRNA aminoacylation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070159</classIRI>
<classLabel>mitochondrial threonyl-tRNA aminoacylation</classLabel>
<newAxiom>&apos;mitochondrial threonyl-tRNA aminoacylation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045186</classIRI>
<classLabel>zonula adherens assembly</classLabel>
<deletedAxiom>&apos;zonula adherens assembly&apos; SubClassOf &apos;cell-cell junction assembly&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070143</classIRI>
<classLabel>mitochondrial alanyl-tRNA aminoacylation</classLabel>
<newAxiom>&apos;mitochondrial alanyl-tRNA aminoacylation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070144</classIRI>
<classLabel>mitochondrial arginyl-tRNA aminoacylation</classLabel>
<newAxiom>&apos;mitochondrial arginyl-tRNA aminoacylation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070145</classIRI>
<classLabel>mitochondrial asparaginyl-tRNA aminoacylation</classLabel>
<newAxiom>&apos;mitochondrial asparaginyl-tRNA aminoacylation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070146</classIRI>
<classLabel>mitochondrial aspartyl-tRNA aminoacylation</classLabel>
<newAxiom>&apos;mitochondrial aspartyl-tRNA aminoacylation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070147</classIRI>
<classLabel>mitochondrial cysteinyl-tRNA aminoacylation</classLabel>
<newAxiom>&apos;mitochondrial cysteinyl-tRNA aminoacylation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070148</classIRI>
<classLabel>mitochondrial glutaminyl-tRNA aminoacylation</classLabel>
<newAxiom>&apos;mitochondrial glutaminyl-tRNA aminoacylation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070149</classIRI>
<classLabel>mitochondrial glutamyl-tRNA aminoacylation</classLabel>
<newAxiom>&apos;mitochondrial glutamyl-tRNA aminoacylation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070150</classIRI>
<classLabel>mitochondrial glycyl-tRNA aminoacylation</classLabel>
<newAxiom>&apos;mitochondrial glycyl-tRNA aminoacylation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070151</classIRI>
<classLabel>mitochondrial histidyl-tRNA aminoacylation</classLabel>
<newAxiom>&apos;mitochondrial histidyl-tRNA aminoacylation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070152</classIRI>
<classLabel>mitochondrial isoleucyl-tRNA aminoacylation</classLabel>
<newAxiom>&apos;mitochondrial isoleucyl-tRNA aminoacylation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070124</classIRI>
<classLabel>mitochondrial translational initiation</classLabel>
<newAxiom>&apos;mitochondrial translational initiation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;mitochondrial translational initiation&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070125</classIRI>
<classLabel>mitochondrial translational elongation</classLabel>
<newAxiom>&apos;mitochondrial translational elongation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;mitochondrial translational elongation&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070126</classIRI>
<classLabel>mitochondrial translational termination</classLabel>
<newAxiom>&apos;mitochondrial translational termination&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;mitochondrial translational termination&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035694</classIRI>
<classLabel>mitochondrial protein catabolic process</classLabel>
<newAxiom>&apos;mitochondrial protein catabolic process&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;mitochondrial protein catabolic process&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035437</classIRI>
<classLabel>maintenance of protein localization in endoplasmic reticulum</classLabel>
<newAxiom>&apos;maintenance of protein localization in endoplasmic reticulum&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;maintenance of protein localization in endoplasmic reticulum&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098968</classIRI>
<classLabel>neurotransmitter receptor transport postsynaptic membrane to endosome</classLabel>
<deletedAxiom>&apos;neurotransmitter receptor transport postsynaptic membrane to endosome&apos; EquivalentTo &apos;protein transport&apos; and (&apos;mediated_by&apos; some &apos;vesicle&apos;) and (&apos;has start location&apos; some &apos;postsynaptic membrane&apos;) and (&apos;transports or maintains localization of&apos; some &apos;neurotransmitter receptor complex&apos;) and (&apos;has target end location&apos; some &apos;postsynaptic early endosome&apos;)</deletedAxiom>
<newAxiom>&apos;neurotransmitter receptor transport postsynaptic membrane to endosome&apos; EquivalentTo &apos;protein transport&apos; and (&apos;has start location&apos; some &apos;postsynaptic membrane&apos;) and (&apos;transports or maintains localization of&apos; some &apos;neurotransmitter receptor complex&apos;) and (&apos;has target end location&apos; some &apos;postsynaptic early endosome&apos;) and (&apos;has causal agent&apos; some &apos;vesicle&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001953</classIRI>
<classLabel>negative regulation of cell-matrix adhesion</classLabel>
<deletedAxiom>&apos;negative regulation of cell-matrix adhesion&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;cell-matrix adhesion&apos;)</deletedAxiom>
<newAxiom>&apos;negative regulation of cell-matrix adhesion&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;cell-matrix adhesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001954</classIRI>
<classLabel>positive regulation of cell-matrix adhesion</classLabel>
<deletedAxiom>&apos;positive regulation of cell-matrix adhesion&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;cell-matrix adhesion&apos;)</deletedAxiom>
<newAxiom>&apos;positive regulation of cell-matrix adhesion&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;cell-matrix adhesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001952</classIRI>
<classLabel>regulation of cell-matrix adhesion</classLabel>
<deletedAxiom>&apos;regulation of cell-matrix adhesion&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;cell-matrix adhesion&apos;)</deletedAxiom>
<newAxiom>&apos;regulation of cell-matrix adhesion&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;cell-matrix adhesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001913</classIRI>
<classLabel>T cell mediated cytotoxicity</classLabel>
<deletedAxiom>&apos;T cell mediated cytotoxicity&apos; EquivalentTo &apos;cell killing&apos; and (&apos;mediated_by&apos; some &apos;T cell&apos;)</deletedAxiom>
<newAxiom>&apos;T cell mediated cytotoxicity&apos; EquivalentTo &apos;cell killing&apos; and (&apos;has causal agent&apos; some &apos;T cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001909</classIRI>
<classLabel>leukocyte mediated cytotoxicity</classLabel>
<deletedAxiom>&apos;leukocyte mediated cytotoxicity&apos; EquivalentTo &apos;cell killing&apos; and (&apos;mediated_by&apos; some &apos;leukocyte&apos;)</deletedAxiom>
<deletedAxiom>&apos;leukocyte mediated cytotoxicity&apos; SubClassOf &apos;mediated_by&apos; some &apos;leukocyte&apos;</deletedAxiom>
<newAxiom>&apos;leukocyte mediated cytotoxicity&apos; SubClassOf &apos;has causal agent&apos; some &apos;leukocyte&apos;</newAxiom>
<newAxiom>&apos;leukocyte mediated cytotoxicity&apos; EquivalentTo &apos;cell killing&apos; and (&apos;has causal agent&apos; some &apos;leukocyte&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098920</classIRI>
<classLabel>retrograde trans-synaptic signaling by lipid</classLabel>
<deletedAxiom>&apos;retrograde trans-synaptic signaling by lipid&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;lipid&apos;) and (&apos;has start location&apos; some &apos;postsynapse&apos;) and (&apos;has end location&apos; some &apos;presynapse&apos;)</deletedAxiom>
<newAxiom>&apos;retrograde trans-synaptic signaling by lipid&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;has start location&apos; some &apos;postsynapse&apos;) and (&apos;has end location&apos; some &apos;presynapse&apos;) and (&apos;has causal agent&apos; some &apos;lipid&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098921</classIRI>
<classLabel>retrograde trans-synaptic signaling by endocannabinoid</classLabel>
<deletedAxiom>&apos;retrograde trans-synaptic signaling by endocannabinoid&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;cannabinoid&apos;) and (&apos;has start location&apos; some &apos;postsynapse&apos;) and (&apos;has end location&apos; some &apos;presynapse&apos;)</deletedAxiom>
<newAxiom>&apos;retrograde trans-synaptic signaling by endocannabinoid&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;has start location&apos; some &apos;postsynapse&apos;) and (&apos;has end location&apos; some &apos;presynapse&apos;) and (&apos;has causal agent&apos; some &apos;cannabinoid&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098924</classIRI>
<classLabel>retrograde trans-synaptic signaling by nitric oxide</classLabel>
<deletedAxiom>&apos;retrograde trans-synaptic signaling by nitric oxide&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;nitric oxide&apos;) and (&apos;has start location&apos; some &apos;postsynapse&apos;) and (&apos;has end location&apos; some &apos;presynapse&apos;)</deletedAxiom>
<newAxiom>&apos;retrograde trans-synaptic signaling by nitric oxide&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;has start location&apos; some &apos;postsynapse&apos;) and (&apos;has end location&apos; some &apos;presynapse&apos;) and (&apos;has causal agent&apos; some &apos;nitric oxide&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098925</classIRI>
<classLabel>retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission</classLabel>
<deletedAxiom>&apos;retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;nitric oxide&apos;) and (&apos;regulates&apos; some &apos;chemical synaptic transmission&apos;) and (&apos;has start location&apos; some &apos;postsynapse&apos;) and (&apos;has end location&apos; some &apos;presynapse&apos;)</deletedAxiom>
<newAxiom>&apos;retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;regulates&apos; some &apos;chemical synaptic transmission&apos;) and (&apos;has start location&apos; some &apos;postsynapse&apos;) and (&apos;has end location&apos; some &apos;presynapse&apos;) and (&apos;has causal agent&apos; some &apos;nitric oxide&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098940</classIRI>
<classLabel>anterograde trans-synaptic signaling by nitric oxide</classLabel>
<deletedAxiom>&apos;anterograde trans-synaptic signaling by nitric oxide&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;nitric oxide&apos;) and (&apos;has start location&apos; some &apos;presynapse&apos;) and (&apos;has end location&apos; some &apos;postsynapse&apos;)</deletedAxiom>
<newAxiom>&apos;anterograde trans-synaptic signaling by nitric oxide&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;has start location&apos; some &apos;presynapse&apos;) and (&apos;has end location&apos; some &apos;postsynapse&apos;) and (&apos;has causal agent&apos; some &apos;nitric oxide&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098941</classIRI>
<classLabel>anterograde trans-synaptic signaling by trans-synaptic protein complex</classLabel>
<deletedAxiom>&apos;anterograde trans-synaptic signaling by trans-synaptic protein complex&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;trans-synaptic protein complex&apos;) and (&apos;has start location&apos; some &apos;presynapse&apos;) and (&apos;has end location&apos; some &apos;postsynapse&apos;)</deletedAxiom>
<newAxiom>&apos;anterograde trans-synaptic signaling by trans-synaptic protein complex&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;has start location&apos; some &apos;presynapse&apos;) and (&apos;has end location&apos; some &apos;postsynapse&apos;) and (&apos;has causal agent&apos; some &apos;trans-synaptic protein complex&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098942</classIRI>
<classLabel>retrograde trans-synaptic signaling by trans-synaptic protein complex</classLabel>
<deletedAxiom>&apos;retrograde trans-synaptic signaling by trans-synaptic protein complex&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;trans-synaptic protein complex&apos;) and (&apos;has start location&apos; some &apos;postsynapse&apos;) and (&apos;has end location&apos; some &apos;presynapse&apos;)</deletedAxiom>
<newAxiom>&apos;retrograde trans-synaptic signaling by trans-synaptic protein complex&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;has start location&apos; some &apos;postsynapse&apos;) and (&apos;has end location&apos; some &apos;presynapse&apos;) and (&apos;has causal agent&apos; some &apos;trans-synaptic protein complex&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098943</classIRI>
<classLabel>neurotransmitter receptor transport, postsynaptic endosome to lysosome</classLabel>
<deletedAxiom>&apos;neurotransmitter receptor transport, postsynaptic endosome to lysosome&apos; EquivalentTo &apos;protein transport&apos; and (&apos;mediated_by&apos; some &apos;vesicle&apos;) and (&apos;transports or maintains localization of&apos; some &apos;neurotransmitter receptor complex&apos;) and (&apos;has target start location&apos; some &apos;postsynaptic endosome&apos;) and (&apos;has target end location&apos; some &apos;lysosome&apos;)</deletedAxiom>
<newAxiom>&apos;neurotransmitter receptor transport, postsynaptic endosome to lysosome&apos; EquivalentTo &apos;protein transport&apos; and (&apos;transports or maintains localization of&apos; some &apos;neurotransmitter receptor complex&apos;) and (&apos;has target start location&apos; some &apos;postsynaptic endosome&apos;) and (&apos;has target end location&apos; some &apos;lysosome&apos;) and (&apos;has causal agent&apos; some &apos;vesicle&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098887</classIRI>
<classLabel>neurotransmitter receptor transport, endosome to postsynaptic membrane</classLabel>
<deletedAxiom>&apos;neurotransmitter receptor transport, endosome to postsynaptic membrane&apos; EquivalentTo &apos;protein transport&apos; and (&apos;mediated_by&apos; some &apos;vesicle&apos;) and (&apos;transports or maintains localization of&apos; some &apos;neurotransmitter receptor complex&apos;) and (&apos;has target start location&apos; some &apos;postsynaptic endosome&apos;) and (&apos;has target end location&apos; some &apos;postsynaptic membrane&apos;)</deletedAxiom>
<newAxiom>&apos;neurotransmitter receptor transport, endosome to postsynaptic membrane&apos; EquivalentTo &apos;protein transport&apos; and (&apos;transports or maintains localization of&apos; some &apos;neurotransmitter receptor complex&apos;) and (&apos;has target start location&apos; some &apos;postsynaptic endosome&apos;) and (&apos;has target end location&apos; some &apos;postsynaptic membrane&apos;) and (&apos;has causal agent&apos; some &apos;vesicle&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098876</classIRI>
<classLabel>vesicle-mediated transport to the plasma membrane</classLabel>
<deletedAxiom>&apos;vesicle-mediated transport to the plasma membrane&apos; EquivalentTo &apos;transport&apos; and (&apos;mediated_by&apos; some &apos;vesicle&apos;) and (&apos;has target end location&apos; some &apos;plasma membrane&apos;)</deletedAxiom>
<newAxiom>&apos;vesicle-mediated transport to the plasma membrane&apos; EquivalentTo &apos;transport&apos; and (&apos;has target end location&apos; some &apos;plasma membrane&apos;) and (&apos;has causal agent&apos; some &apos;vesicle&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001849</classIRI>
<classLabel>complement component C1q binding</classLabel>
<newAxiom>&apos;complement component C1q binding&apos; SubClassOf &apos;has input&apos; some http://purl.obolibrary.org/obo/GO_0062167</newAxiom>
<newAxiom>&apos;complement component C1q binding&apos; SubClassOf &apos;protein-containing complex binding&apos;</newAxiom>
<newAxiom>&apos;complement component C1q binding&apos; EquivalentTo &apos;complement binding&apos; and (&apos;has input&apos; some http://purl.obolibrary.org/obo/GO_0062167)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905071</classIRI>
<classLabel>tight junction disassembly</classLabel>
<deletedAxiom>&apos;tight junction disassembly&apos; SubClassOf &apos;cellular component disassembly&apos;</deletedAxiom>
<newAxiom>&apos;tight junction disassembly&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0150147</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035278</classIRI>
<classLabel>miRNA mediated inhibition of translation</classLabel>
<deletedAxiom>&apos;miRNA mediated inhibition of translation&apos; EquivalentTo &apos;biological_process&apos; and (&apos;mediated_by&apos; some &apos;miRNA&apos;) and (&apos;directly negatively regulates&apos; some &apos;translation&apos;)</deletedAxiom>
<deletedAxiom>&apos;miRNA mediated inhibition of translation&apos; SubClassOf &apos;mediated_by&apos; some &apos;miRNA&apos;</deletedAxiom>
<newAxiom>&apos;miRNA mediated inhibition of translation&apos; EquivalentTo &apos;biological_process&apos; and (&apos;has causal agent&apos; some &apos;miRNA&apos;) and (&apos;directly negatively regulates&apos; some &apos;translation&apos;)</newAxiom>
<newAxiom>&apos;miRNA mediated inhibition of translation&apos; SubClassOf &apos;has causal agent&apos; some &apos;miRNA&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060154</classIRI>
<classLabel>cellular process regulating host cell cycle in response to virus</classLabel>
<deletedAxiom>&apos;cellular process regulating host cell cycle in response to virus&apos; SubClassOf &apos;regulation of cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular process regulating host cell cycle in response to virus&apos; SubClassOf &apos;cellular response to virus&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050794</classIRI>
<classLabel>regulation of cellular process</classLabel>
<deletedAxiom>&apos;regulation of cellular process&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;cellular process&apos;)</deletedAxiom>
<newAxiom>&apos;regulation of cellular process&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;cellular process&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015903</classIRI>
<classLabel>fluconazole transport</classLabel>
<deletedAxiom>&apos;fluconazole transport&apos; SubClassOf &apos;azole transport&apos;</deletedAxiom>
<newAxiom>&apos;fluconazole transport&apos; SubClassOf &apos;nitrogen compound transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015817</classIRI>
<classLabel>histidine transport</classLabel>
<deletedAxiom>&apos;histidine transport&apos; SubClassOf &apos;azole transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015888</classIRI>
<classLabel>thiamine transport</classLabel>
<deletedAxiom>&apos;thiamine transport&apos; SubClassOf &apos;azole transport&apos;</deletedAxiom>
<newAxiom>&apos;thiamine transport&apos; SubClassOf &apos;nitrogen compound transport&apos;</newAxiom>
<newAxiom>&apos;thiamine transport&apos; SubClassOf &apos;organic substance transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015899</classIRI>
<classLabel>aminotriazole transport</classLabel>
<deletedAxiom>&apos;aminotriazole transport&apos; SubClassOf &apos;azole transport&apos;</deletedAxiom>
<newAxiom>&apos;aminotriazole transport&apos; SubClassOf &apos;nitrogen compound transport&apos;</newAxiom>
<newAxiom>&apos;aminotriazole transport&apos; SubClassOf &apos;organic substance transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039675</classIRI>
<classLabel>exit of virus from host cell nucleus through nuclear pore</classLabel>
<deletedAxiom>&apos;exit of virus from host cell nucleus through nuclear pore&apos; SubClassOf &apos;mediated_by&apos; some &apos;nuclear pore&apos;</deletedAxiom>
<deletedAxiom>&apos;exit of virus from host cell nucleus through nuclear pore&apos; EquivalentTo &apos;exit of virus from host cell nucleus&apos; and (&apos;mediated_by&apos; some &apos;nuclear pore&apos;)</deletedAxiom>
<newAxiom>&apos;exit of virus from host cell nucleus through nuclear pore&apos; SubClassOf &apos;has causal agent&apos; some &apos;nuclear pore&apos;</newAxiom>
<newAxiom>&apos;exit of virus from host cell nucleus through nuclear pore&apos; EquivalentTo &apos;exit of virus from host cell nucleus&apos; and (&apos;has causal agent&apos; some &apos;nuclear pore&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039660</classIRI>
<classLabel>structural constituent of virion</classLabel>
<newAxiom>&apos;structural constituent of virion&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;cellular organisms&apos;))</newAxiom>
<newAxiom>&apos;structural constituent of virion&apos; DisjointWith &apos;in taxon&apos; some &apos;cellular organisms&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904702</classIRI>
<classLabel>regulation of protein localization to cell-cell adherens junction</classLabel>
<deletedAxiom>&apos;regulation of protein localization to cell-cell adherens junction&apos; SubClassOf &apos;regulates&apos; some &apos;protein localization to cell-cell adherens junction&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of protein localization to cell-cell adherens junction&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;protein localization to cell-cell adherens junction&apos;)</deletedAxiom>
<newAxiom>&apos;regulation of protein localization to cell-cell adherens junction&apos; SubClassOf &apos;regulates&apos; some &apos;protein localization to adherens junction&apos;</newAxiom>
<newAxiom>&apos;regulation of protein localization to cell-cell adherens junction&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;protein localization to adherens junction&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904703</classIRI>
<classLabel>negative regulation of protein localization to cell-cell adherens junction</classLabel>
<deletedAxiom>&apos;negative regulation of protein localization to cell-cell adherens junction&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;protein localization to cell-cell adherens junction&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein localization to cell-cell adherens junction&apos; SubClassOf &apos;negatively regulates&apos; some &apos;protein localization to cell-cell adherens junction&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein localization to cell-cell adherens junction&apos; SubClassOf &apos;negative regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of protein localization to cell-cell adherens junction&apos; SubClassOf &apos;negatively regulates&apos; some &apos;protein localization to adherens junction&apos;</newAxiom>
<newAxiom>&apos;negative regulation of protein localization to cell-cell adherens junction&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0150119</newAxiom>
<newAxiom>&apos;negative regulation of protein localization to cell-cell adherens junction&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;protein localization to adherens junction&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904704</classIRI>
<classLabel>positive regulation of protein localization to cell-cell adherens junction</classLabel>
<deletedAxiom>&apos;positive regulation of protein localization to cell-cell adherens junction&apos; SubClassOf &apos;positively regulates&apos; some &apos;protein localization to cell-cell adherens junction&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein localization to cell-cell adherens junction&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;protein localization to cell-cell adherens junction&apos;)</deletedAxiom>
<newAxiom>&apos;positive regulation of protein localization to cell-cell adherens junction&apos; SubClassOf &apos;positively regulates&apos; some &apos;protein localization to adherens junction&apos;</newAxiom>
<newAxiom>&apos;positive regulation of protein localization to cell-cell adherens junction&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;protein localization to adherens junction&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904696</classIRI>
<classLabel>protein localization to cell-cell adherens junction</classLabel>
<deletedAxiom>&apos;protein localization to cell-cell adherens junction&apos; SubClassOf &apos;protein localization to adherens junction&apos;</deletedAxiom>
<deletedAxiom>&apos;protein localization to cell-cell adherens junction&apos; EquivalentTo &apos;protein localization&apos; and (&apos;has target end location&apos; some &apos;cell-cell adherens junction&apos;)</deletedAxiom>
<deletedAxiom>&apos;protein localization to cell-cell adherens junction&apos; SubClassOf &apos;protein localization to cell-cell junction&apos;</deletedAxiom>
<deletedAxiom>&apos;protein localization to cell-cell adherens junction&apos; SubClassOf &apos;has target end location&apos; some &apos;cell-cell adherens junction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005911</classIRI>
<classLabel>cell-cell junction</classLabel>
<deletedAxiom>&apos;cell-cell junction&apos; SubClassOf &apos;cell junction&apos;</deletedAxiom>
<newAxiom>&apos;cell-cell junction&apos; SubClassOf &apos;anchoring junction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005912</classIRI>
<classLabel>adherens junction</classLabel>
<deletedAxiom>&apos;adherens junction&apos; SubClassOf &apos;anchoring junction&apos;</deletedAxiom>
<newAxiom>&apos;adherens junction&apos; SubClassOf &apos;cell-cell junction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005913</classIRI>
<classLabel>cell-cell adherens junction</classLabel>
<deletedAxiom>&apos;cell-cell adherens junction&apos; SubClassOf &apos;cell-cell junction&apos;</deletedAxiom>
<deletedAxiom>&apos;cell-cell adherens junction&apos; SubClassOf &apos;adherens junction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005914</classIRI>
<classLabel>spot adherens junction</classLabel>
<deletedAxiom>&apos;spot adherens junction&apos; SubClassOf &apos;cell-cell adherens junction&apos;</deletedAxiom>
<newAxiom>&apos;spot adherens junction&apos; SubClassOf &apos;adherens junction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005915</classIRI>
<classLabel>zonula adherens</classLabel>
<deletedAxiom>&apos;zonula adherens&apos; SubClassOf &apos;cell-cell adherens junction&apos;</deletedAxiom>
<newAxiom>&apos;zonula adherens&apos; SubClassOf &apos;adherens junction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005916</classIRI>
<classLabel>fascia adherens</classLabel>
<deletedAxiom>&apos;fascia adherens&apos; SubClassOf &apos;cell-cell adherens junction&apos;</deletedAxiom>
<newAxiom>&apos;fascia adherens&apos; SubClassOf &apos;cell-cell junction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005924</classIRI>
<classLabel>cell-substrate adherens junction</classLabel>
<deletedAxiom>&apos;cell-substrate adherens junction&apos; SubClassOf &apos;adherens junction&apos;</deletedAxiom>
<deletedAxiom>&apos;cell-substrate adherens junction&apos; SubClassOf &apos;cell-substrate junction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005925</classIRI>
<classLabel>focal adhesion</classLabel>
<deletedAxiom>&apos;focal adhesion&apos; SubClassOf &apos;cell-substrate adherens junction&apos;</deletedAxiom>
<newAxiom>&apos;focal adhesion&apos; SubClassOf &apos;cell-substrate junction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005926</classIRI>
<classLabel>connecting hemi-adherens junction</classLabel>
<deletedAxiom>&apos;connecting hemi-adherens junction&apos; SubClassOf &apos;cell-substrate adherens junction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005927</classIRI>
<classLabel>muscle tendon junction</classLabel>
<deletedAxiom>&apos;muscle tendon junction&apos; SubClassOf &apos;cell-substrate adherens junction&apos;</deletedAxiom>
<newAxiom>&apos;muscle tendon junction&apos; SubClassOf &apos;cell-substrate junction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005928</classIRI>
<classLabel>apical hemi-adherens junction</classLabel>
<deletedAxiom>&apos;apical hemi-adherens junction&apos; SubClassOf &apos;cell-substrate adherens junction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030954</classIRI>
<classLabel>astral microtubule nucleation</classLabel>
<deletedAxiom>&apos;astral microtubule nucleation&apos; EquivalentTo &apos;microtubule nucleation&apos; and (&apos;mediated_by&apos; some &apos;microtubule organizing center&apos;) and (&apos;results_in_organization_of&apos; some &apos;astral microtubule&apos;)</deletedAxiom>
<newAxiom>&apos;astral microtubule nucleation&apos; EquivalentTo &apos;microtubule nucleation&apos; and (&apos;results_in_organization_of&apos; some &apos;astral microtubule&apos;) and (&apos;has causal agent&apos; some &apos;microtubule organizing center&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030682</classIRI>
<classLabel>evasion or tolerance of host defenses</classLabel>
<deletedAxiom>&apos;evasion or tolerance of host defenses&apos; SubClassOf &apos;evasion or tolerance of defenses of other organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030683</classIRI>
<classLabel>evasion or tolerance by virus of host immune response</classLabel>
<deletedAxiom>&apos;evasion or tolerance by virus of host immune response&apos; SubClassOf &apos;evasion or tolerance of host immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0040033</classIRI>
<classLabel>negative regulation of translation, ncRNA-mediated</classLabel>
<deletedAxiom>&apos;negative regulation of translation, ncRNA-mediated&apos; EquivalentTo &apos;regulation of biological process&apos; and (&apos;mediated_by&apos; some &apos;ncRNA&apos;) and (&apos;negatively regulates&apos; some &apos;translation&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of translation, ncRNA-mediated&apos; SubClassOf &apos;mediated_by&apos; some &apos;ncRNA&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of translation, ncRNA-mediated&apos; EquivalentTo &apos;regulation of biological process&apos; and (&apos;negatively regulates&apos; some &apos;translation&apos;) and (&apos;has causal agent&apos; some &apos;ncRNA&apos;)</newAxiom>
<newAxiom>&apos;negative regulation of translation, ncRNA-mediated&apos; SubClassOf &apos;has causal agent&apos; some &apos;ncRNA&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005602</classIRI>
<classLabel>complement component C1 complex</classLabel>
<newAxiom>&apos;complement component C1 complex&apos; SubClassOf &apos;has_part&apos; some http://purl.obolibrary.org/obo/GO_0062167</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005484</classIRI>
<classLabel>SNAP receptor activity</classLabel>
<deletedAxiom>&apos;SNAP receptor activity&apos; SubClassOf &apos;protein binding&apos;</deletedAxiom>
<newAxiom>&apos;SNAP receptor activity&apos; SubClassOf &apos;protein binding, bridging&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900160</classIRI>
<classLabel>plastid DNA packaging</classLabel>
<newAxiom>&apos;plastid DNA packaging&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Amoebozoa&apos;))</newAxiom>
<newAxiom>&apos;plastid DNA packaging&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Bacteria&apos;))</newAxiom>
<newAxiom>&apos;plastid DNA packaging&apos; DisjointWith &apos;in taxon&apos; some &apos;Metazoa&apos;</newAxiom>
<newAxiom>&apos;plastid DNA packaging&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Archaea&apos;))</newAxiom>
<newAxiom>&apos;plastid DNA packaging&apos; DisjointWith &apos;in taxon&apos; some &apos;Amoebozoa&apos;</newAxiom>
<newAxiom>&apos;plastid DNA packaging&apos; DisjointWith &apos;in taxon&apos; some &apos;Fungi&apos;</newAxiom>
<newAxiom>&apos;plastid DNA packaging&apos; DisjointWith &apos;in taxon&apos; some &apos;Choanoflagellata&apos;</newAxiom>
<newAxiom>&apos;plastid DNA packaging&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Choanoflagellata&apos;))</newAxiom>
<newAxiom>&apos;plastid DNA packaging&apos; DisjointWith &apos;in taxon&apos; some &apos;Archaea&apos;</newAxiom>
<newAxiom>&apos;plastid DNA packaging&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Fungi&apos;))</newAxiom>
<newAxiom>&apos;plastid DNA packaging&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Metazoa&apos;))</newAxiom>
<newAxiom>&apos;plastid DNA packaging&apos; DisjointWith &apos;in taxon&apos; some &apos;Bacteria&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900177</classIRI>
<classLabel>regulation of aflatoxin biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of aflatoxin biosynthetic process&apos; SubClassOf &apos;regulation of phenylpropanoid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of aflatoxin biosynthetic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900178</classIRI>
<classLabel>negative regulation of aflatoxin biosynthetic process</classLabel>
<newAxiom>&apos;negative regulation of aflatoxin biosynthetic process&apos; SubClassOf &apos;negative regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900179</classIRI>
<classLabel>positive regulation of aflatoxin biosynthetic process</classLabel>
<newAxiom>&apos;positive regulation of aflatoxin biosynthetic process&apos; SubClassOf &apos;positive regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030317</classIRI>
<classLabel>flagellated sperm motility</classLabel>
<deletedAxiom>&apos;flagellated sperm motility&apos; EquivalentTo &apos;movement of cell or subcellular component&apos; and (&apos;has input&apos; some &apos;sperm&apos;)</deletedAxiom>
<deletedAxiom>&apos;flagellated sperm motility&apos; SubClassOf &apos;has input&apos; some &apos;sperm&apos;</deletedAxiom>
<newAxiom>&apos;flagellated sperm motility&apos; EquivalentTo &apos;cilium-dependent cell motility&apos; and (&apos;results in movement of&apos; some &apos;sperm&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019911</classIRI>
<classLabel>structural constituent of myelin sheath</classLabel>
<newAxiom>&apos;structural constituent of myelin sheath&apos; SubClassOf &apos;in taxon&apos; only &apos;Metazoa&apos;</newAxiom>
<newAxiom>&apos;structural constituent of myelin sheath&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Metazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005213</classIRI>
<classLabel>structural constituent of chorion</classLabel>
<deletedAxiom>&apos;structural constituent of chorion&apos; SubClassOf &apos;occurs in&apos; some &apos;chorion&apos;</deletedAxiom>
<deletedAxiom>&apos;structural constituent of chorion&apos; EquivalentTo &apos;structural molecule activity&apos; and (&apos;occurs in&apos; some &apos;chorion&apos;)</deletedAxiom>
<newAxiom>&apos;structural constituent of chorion&apos; SubClassOf &apos;occurs in&apos; some &apos;chorion&apos;</newAxiom>
<newAxiom>&apos;structural constituent of chorion&apos; EquivalentTo &apos;structural molecule activity&apos; and (&apos;occurs in&apos; some &apos;chorion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019724</classIRI>
<classLabel>B cell mediated immunity</classLabel>
<deletedAxiom>&apos;B cell mediated immunity&apos; SubClassOf &apos;mediated_by&apos; some &apos;B cell&apos;</deletedAxiom>
<deletedAxiom>&apos;B cell mediated immunity&apos; EquivalentTo &apos;immune system process&apos; and (&apos;mediated_by&apos; some &apos;B cell&apos;)</deletedAxiom>
<newAxiom>&apos;B cell mediated immunity&apos; SubClassOf &apos;has causal agent&apos; some &apos;B cell&apos;</newAxiom>
<newAxiom>&apos;B cell mediated immunity&apos; EquivalentTo &apos;immune system process&apos; and (&apos;has causal agent&apos; some &apos;B cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019725</classIRI>
<classLabel>cellular homeostasis</classLabel>
<newAxiom>&apos;cellular homeostasis&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;cellular organisms&apos;</newAxiom>
<newAxiom>&apos;cellular homeostasis&apos; SubClassOf &apos;in taxon&apos; only &apos;cellular organisms&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005199</classIRI>
<classLabel>structural constituent of cell wall</classLabel>
<newAxiom>&apos;structural constituent of cell wall&apos; DisjointWith &apos;in taxon&apos; some &apos;Metazoa&apos;</newAxiom>
<newAxiom>&apos;structural constituent of cell wall&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Metazoa&apos;))</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030055</classIRI>
<classLabel>cell-substrate junction</classLabel>
<deletedAxiom>&apos;cell-substrate junction&apos; SubClassOf &apos;cell junction&apos;</deletedAxiom>
<newAxiom>&apos;cell-substrate junction&apos; SubClassOf &apos;anchoring junction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030057</classIRI>
<classLabel>desmosome</classLabel>
<deletedAxiom>&apos;desmosome&apos; SubClassOf &apos;anchoring junction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019661</classIRI>
<classLabel>glucose catabolic process to lactate via pyruvate</classLabel>
<deletedAxiom>&apos;glucose catabolic process to lactate via pyruvate&apos; EquivalentTo &apos;glucose catabolic process&apos; and (&apos;has intermediate&apos; some &apos;pyruvate&apos;) and (&apos;starts with&apos; some &apos;canonical glycolysis&apos;) and (&apos;has primary output&apos; some &apos;lactate&apos;) and (&apos;has primary input&apos; some &apos;glucose&apos;)</deletedAxiom>
<deletedAxiom>&apos;glucose catabolic process to lactate via pyruvate&apos; SubClassOf &apos;has intermediate&apos; some &apos;pyruvate&apos;</deletedAxiom>
<newAxiom>&apos;glucose catabolic process to lactate via pyruvate&apos; EquivalentTo &apos;glucose catabolic process&apos; and (&apos;starts with&apos; some &apos;canonical glycolysis&apos;) and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;pyruvate&apos;) and (&apos;has primary output&apos; some &apos;lactate&apos;) and (&apos;has primary input&apos; some &apos;glucose&apos;)</newAxiom>
<newAxiom>&apos;glucose catabolic process to lactate via pyruvate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;pyruvate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030034</classIRI>
<classLabel>microvillar actin bundle assembly</classLabel>
<newAxiom>&apos;microvillar actin bundle assembly&apos; SubClassOf &apos;in taxon&apos; only &apos;Metazoa&apos;</newAxiom>
<newAxiom>&apos;microvillar actin bundle assembly&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Metazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900689</classIRI>
<classLabel>regulation of gliotoxin biosynthetic process</classLabel>
<newAxiom>&apos;regulation of gliotoxin biosynthetic process&apos; SubClassOf &apos;regulation of cellular amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900690</classIRI>
<classLabel>negative regulation of gliotoxin biosynthetic process</classLabel>
<newAxiom>&apos;negative regulation of gliotoxin biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900691</classIRI>
<classLabel>positive regulation of gliotoxin biosynthetic process</classLabel>
<newAxiom>&apos;positive regulation of gliotoxin biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019512</classIRI>
<classLabel>lactose catabolic process via tagatose-6-phosphate</classLabel>
<deletedAxiom>&apos;lactose catabolic process via tagatose-6-phosphate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some &apos;beta-D-tagatofuranose 6-phosphate&apos;) and (&apos;has primary input&apos; some &apos;lactose&apos;)</deletedAxiom>
<deletedAxiom>&apos;lactose catabolic process via tagatose-6-phosphate&apos; SubClassOf &apos;has intermediate&apos; some &apos;beta-D-tagatofuranose 6-phosphate&apos;</deletedAxiom>
<newAxiom>&apos;lactose catabolic process via tagatose-6-phosphate&apos; EquivalentTo &apos;catabolic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;beta-D-tagatofuranose 6-phosphate&apos;) and (&apos;has primary input&apos; some &apos;lactose&apos;)</newAxiom>
<newAxiom>&apos;lactose catabolic process via tagatose-6-phosphate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;beta-D-tagatofuranose 6-phosphate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019515</classIRI>
<classLabel>lactose catabolic process via UDP-galactose</classLabel>
<deletedAxiom>&apos;lactose catabolic process via UDP-galactose&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some &apos;UDP-D-galactose&apos;) and (&apos;has primary input&apos; some &apos;lactose&apos;)</deletedAxiom>
<deletedAxiom>&apos;lactose catabolic process via UDP-galactose&apos; SubClassOf &apos;has intermediate&apos; some &apos;UDP-D-galactose&apos;</deletedAxiom>
<newAxiom>&apos;lactose catabolic process via UDP-galactose&apos; EquivalentTo &apos;catabolic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;UDP-D-galactose&apos;) and (&apos;has primary input&apos; some &apos;lactose&apos;)</newAxiom>
<newAxiom>&apos;lactose catabolic process via UDP-galactose&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;UDP-D-galactose&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019549</classIRI>
<classLabel>glutamate catabolic process to succinate via succinate semialdehyde</classLabel>
<deletedAxiom>&apos;glutamate catabolic process to succinate via succinate semialdehyde&apos; SubClassOf &apos;has intermediate&apos; some &apos;succinic semialdehyde&apos;</deletedAxiom>
<deletedAxiom>&apos;glutamate catabolic process to succinate via succinate semialdehyde&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some &apos;succinic semialdehyde&apos;) and (&apos;has primary output&apos; some &apos;succinate(2-)&apos;) and (&apos;has primary input&apos; some &apos;glutamate(2-)&apos;)</deletedAxiom>
<newAxiom>&apos;glutamate catabolic process to succinate via succinate semialdehyde&apos; EquivalentTo &apos;catabolic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;succinic semialdehyde&apos;) and (&apos;has primary output&apos; some &apos;succinate(2-)&apos;) and (&apos;has primary input&apos; some &apos;glutamate(2-)&apos;)</newAxiom>
<newAxiom>&apos;glutamate catabolic process to succinate via succinate semialdehyde&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;succinic semialdehyde&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019574</classIRI>
<classLabel>sucrose catabolic process via 3&apos;-ketosucrose</classLabel>
<deletedAxiom>&apos;sucrose catabolic process via 3&apos;-ketosucrose&apos; SubClassOf &apos;has intermediate&apos; some &apos;3-ketosucrose&apos;</deletedAxiom>
<deletedAxiom>&apos;sucrose catabolic process via 3&apos;-ketosucrose&apos; SubClassOf &apos;has intermediate&apos; some &apos;fructose&apos;</deletedAxiom>
<deletedAxiom>&apos;sucrose catabolic process via 3&apos;-ketosucrose&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has_part&apos; some &apos;fructokinase activity&apos;) and (&apos;has_part&apos; some &apos;3-ketoglucose-reductase activity&apos;) and (&apos;has intermediate&apos; some &apos;3-ketosucrose&apos;) and (&apos;has intermediate&apos; some &apos;fructose&apos;) and (&apos;starts with&apos; some &apos;glucoside 3-dehydrogenase activity&apos;) and (&apos;has primary output&apos; some &apos;glucose&apos;) and (&apos;has primary output&apos; some &apos;D-fructose 6-phosphate&apos;) and (&apos;has primary input&apos; some &apos;sucrose&apos;)</deletedAxiom>
<newAxiom>&apos;sucrose catabolic process via 3&apos;-ketosucrose&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;fructose&apos;</newAxiom>
<newAxiom>&apos;sucrose catabolic process via 3&apos;-ketosucrose&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has_part&apos; some &apos;fructokinase activity&apos;) and (&apos;has_part&apos; some &apos;3-ketoglucose-reductase activity&apos;) and (&apos;starts with&apos; some &apos;glucoside 3-dehydrogenase activity&apos;) and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;3-ketosucrose&apos;) and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;fructose&apos;) and (&apos;has primary output&apos; some &apos;glucose&apos;) and (&apos;has primary output&apos; some &apos;D-fructose 6-phosphate&apos;) and (&apos;has primary input&apos; some &apos;sucrose&apos;)</newAxiom>
<newAxiom>&apos;sucrose catabolic process via 3&apos;-ketosucrose&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;3-ketosucrose&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044510</classIRI>
<classLabel>envenomation resulting in positive regulation of signal transduction in other organism</classLabel>
<deletedAxiom>&apos;envenomation resulting in positive regulation of signal transduction in other organism&apos; SubClassOf &apos;has_part&apos; some &apos;positive regulation of signal transduction in other organism&apos;</deletedAxiom>
<newAxiom>&apos;envenomation resulting in positive regulation of signal transduction in other organism&apos; SubClassOf &apos;has_part&apos; some &apos;positive regulation by symbiont of host signal transduction pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044502</classIRI>
<classLabel>positive regulation of signal transduction in other organism</classLabel>
<deletedAxiom>&apos;positive regulation of signal transduction in other organism&apos; SubClassOf &apos;modulation of signal transduction in other organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019453</classIRI>
<classLabel>L-cysteine catabolic process via cystine</classLabel>
<deletedAxiom>&apos;L-cysteine catabolic process via cystine&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some &apos;cystine&apos;) and (&apos;has primary input&apos; some &apos;L-cysteine&apos;)</deletedAxiom>
<deletedAxiom>&apos;L-cysteine catabolic process via cystine&apos; SubClassOf &apos;has intermediate&apos; some &apos;cystine&apos;</deletedAxiom>
<newAxiom>&apos;L-cysteine catabolic process via cystine&apos; EquivalentTo &apos;catabolic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;cystine&apos;) and (&apos;has primary input&apos; some &apos;L-cysteine&apos;)</newAxiom>
<newAxiom>&apos;L-cysteine catabolic process via cystine&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;cystine&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019454</classIRI>
<classLabel>L-cysteine catabolic process via cystine, using glutathione-cystine transhydrogenase</classLabel>
<deletedAxiom>&apos;L-cysteine catabolic process via cystine, using glutathione-cystine transhydrogenase&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some &apos;cystine&apos;) and (&apos;has_participant&apos; some &apos;glutathione-cystine transhydrogenase activity&apos;) and (&apos;has primary input&apos; some &apos;L-cysteine&apos;)</deletedAxiom>
<newAxiom>&apos;L-cysteine catabolic process via cystine, using glutathione-cystine transhydrogenase&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has_participant&apos; some &apos;glutathione-cystine transhydrogenase activity&apos;) and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;cystine&apos;) and (&apos;has primary input&apos; some &apos;L-cysteine&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019455</classIRI>
<classLabel>L-cysteine catabolic process via cystine, using cystine reductase</classLabel>
<deletedAxiom>&apos;L-cysteine catabolic process via cystine, using cystine reductase&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some &apos;cystine&apos;) and (&apos;has_participant&apos; some &apos;cystine reductase activity&apos;) and (&apos;has primary input&apos; some &apos;L-cysteine&apos;)</deletedAxiom>
<newAxiom>&apos;L-cysteine catabolic process via cystine, using cystine reductase&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has_participant&apos; some &apos;cystine reductase activity&apos;) and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;cystine&apos;) and (&apos;has primary input&apos; some &apos;L-cysteine&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019458</classIRI>
<classLabel>methionine catabolic process via 2-oxobutanoate</classLabel>
<deletedAxiom>&apos;methionine catabolic process via 2-oxobutanoate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some &apos;2-oxobutanoate&apos;) and (&apos;has primary input&apos; some &apos;methioninate&apos;)</deletedAxiom>
<deletedAxiom>&apos;methionine catabolic process via 2-oxobutanoate&apos; SubClassOf &apos;has intermediate&apos; some &apos;2-oxobutanoate&apos;</deletedAxiom>
<newAxiom>&apos;methionine catabolic process via 2-oxobutanoate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;2-oxobutanoate&apos;</newAxiom>
<newAxiom>&apos;methionine catabolic process via 2-oxobutanoate&apos; EquivalentTo &apos;catabolic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;2-oxobutanoate&apos;) and (&apos;has primary input&apos; some &apos;methioninate&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019466</classIRI>
<classLabel>ornithine catabolic process via proline</classLabel>
<deletedAxiom>&apos;ornithine catabolic process via proline&apos; SubClassOf &apos;has intermediate&apos; some &apos;prolinate&apos;</deletedAxiom>
<deletedAxiom>&apos;ornithine catabolic process via proline&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some &apos;prolinate&apos;) and (&apos;has primary input&apos; some &apos;ornithinate&apos;)</deletedAxiom>
<newAxiom>&apos;ornithine catabolic process via proline&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;prolinate&apos;</newAxiom>
<newAxiom>&apos;ornithine catabolic process via proline&apos; EquivalentTo &apos;catabolic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;prolinate&apos;) and (&apos;has primary input&apos; some &apos;ornithinate&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044414</classIRI>
<classLabel>suppression of host defenses</classLabel>
<newAxiom>&apos;suppression of host defenses&apos; SubClassOf &apos;negative regulation of defense response&apos;</newAxiom>
<newAxiom>&apos;suppression of host defenses&apos; SubClassOf &apos;modulation by symbiont of host defense response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044416</classIRI>
<classLabel>induction by symbiont of host defense response</classLabel>
<deletedAxiom>&apos;induction by symbiont of host defense response&apos; SubClassOf &apos;positive regulation by symbiont of host defense response&apos;</deletedAxiom>
<newAxiom>&apos;induction by symbiont of host defense response&apos; SubClassOf &apos;positive regulation of defense response&apos;</newAxiom>
<newAxiom>&apos;induction by symbiont of host defense response&apos; SubClassOf &apos;modulation by symbiont of host defense response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044411</classIRI>
<classLabel>entry into host through host barriers</classLabel>
<deletedAxiom>&apos;entry into host through host barriers&apos; SubClassOf &apos;entry into host&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019397</classIRI>
<classLabel>gallate catabolic process via 2-pyrone-4,6-dicarboxylate</classLabel>
<deletedAxiom>&apos;gallate catabolic process via 2-pyrone-4,6-dicarboxylate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some &apos;2-oxo-2H-pyran-4,6-dicarboxylate&apos;) and (&apos;has primary input&apos; some &apos;gallate&apos;)</deletedAxiom>
<deletedAxiom>&apos;gallate catabolic process via 2-pyrone-4,6-dicarboxylate&apos; SubClassOf &apos;has intermediate&apos; some &apos;2-oxo-2H-pyran-4,6-dicarboxylate&apos;</deletedAxiom>
<newAxiom>&apos;gallate catabolic process via 2-pyrone-4,6-dicarboxylate&apos; EquivalentTo &apos;catabolic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;2-oxo-2H-pyran-4,6-dicarboxylate&apos;) and (&apos;has primary input&apos; some &apos;gallate&apos;)</newAxiom>
<newAxiom>&apos;gallate catabolic process via 2-pyrone-4,6-dicarboxylate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;2-oxo-2H-pyran-4,6-dicarboxylate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900864</classIRI>
<classLabel>mitochondrial RNA modification</classLabel>
<newAxiom>&apos;mitochondrial RNA modification&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900865</classIRI>
<classLabel>chloroplast RNA modification</classLabel>
<newAxiom>&apos;chloroplast RNA modification&apos; DisjointWith &apos;in taxon&apos; some &apos;Amoebozoa&apos;</newAxiom>
<newAxiom>&apos;chloroplast RNA modification&apos; DisjointWith &apos;in taxon&apos; some &apos;Fungi&apos;</newAxiom>
<newAxiom>&apos;chloroplast RNA modification&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Metazoa&apos;))</newAxiom>
<newAxiom>&apos;chloroplast RNA modification&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Amoebozoa&apos;))</newAxiom>
<newAxiom>&apos;chloroplast RNA modification&apos; DisjointWith &apos;in taxon&apos; some &apos;Choanoflagellata&apos;</newAxiom>
<newAxiom>&apos;chloroplast RNA modification&apos; DisjointWith &apos;in taxon&apos; some &apos;Metazoa&apos;</newAxiom>
<newAxiom>&apos;chloroplast RNA modification&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Choanoflagellata&apos;))</newAxiom>
<newAxiom>&apos;chloroplast RNA modification&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Fungi&apos;))</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900871</classIRI>
<classLabel>chloroplast mRNA modification</classLabel>
<newAxiom>&apos;chloroplast mRNA modification&apos; DisjointWith &apos;in taxon&apos; some &apos;Amoebozoa&apos;</newAxiom>
<newAxiom>&apos;chloroplast mRNA modification&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Amoebozoa&apos;))</newAxiom>
<newAxiom>&apos;chloroplast mRNA modification&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Choanoflagellata&apos;))</newAxiom>
<newAxiom>&apos;chloroplast mRNA modification&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Metazoa&apos;))</newAxiom>
<newAxiom>&apos;chloroplast mRNA modification&apos; DisjointWith &apos;in taxon&apos; some &apos;Metazoa&apos;</newAxiom>
<newAxiom>&apos;chloroplast mRNA modification&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Fungi&apos;))</newAxiom>
<newAxiom>&apos;chloroplast mRNA modification&apos; DisjointWith &apos;in taxon&apos; some &apos;Choanoflagellata&apos;</newAxiom>
<newAxiom>&apos;chloroplast mRNA modification&apos; DisjointWith &apos;in taxon&apos; some &apos;Fungi&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010979</classIRI>
<classLabel>regulation of vitamin D 24-hydroxylase activity</classLabel>
<deletedAxiom>&apos;regulation of vitamin D 24-hydroxylase activity&apos; SubClassOf &apos;regulation of oxidoreductase activity&apos;</deletedAxiom>
<newAxiom>&apos;regulation of vitamin D 24-hydroxylase activity&apos; SubClassOf &apos;regulation of monooxygenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010980</classIRI>
<classLabel>positive regulation of vitamin D 24-hydroxylase activity</classLabel>
<deletedAxiom>&apos;positive regulation of vitamin D 24-hydroxylase activity&apos; SubClassOf &apos;positive regulation of oxidoreductase activity&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of vitamin D 24-hydroxylase activity&apos; SubClassOf &apos;positive regulation of monooxygenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019343</classIRI>
<classLabel>cysteine biosynthetic process via cystathionine</classLabel>
<deletedAxiom>&apos;cysteine biosynthetic process via cystathionine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;cystathionine&apos;) and (&apos;has primary output&apos; some &apos;cysteinium&apos;)</deletedAxiom>
<deletedAxiom>&apos;cysteine biosynthetic process via cystathionine&apos; SubClassOf &apos;has intermediate&apos; some &apos;cystathionine&apos;</deletedAxiom>
<newAxiom>&apos;cysteine biosynthetic process via cystathionine&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;cystathionine&apos;) and (&apos;has primary output&apos; some &apos;cysteinium&apos;)</newAxiom>
<newAxiom>&apos;cysteine biosynthetic process via cystathionine&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;cystathionine&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019345</classIRI>
<classLabel>cysteine biosynthetic process via S-sulfo-L-cysteine</classLabel>
<deletedAxiom>&apos;cysteine biosynthetic process via S-sulfo-L-cysteine&apos; SubClassOf &apos;has intermediate&apos; some &apos;S-sulfo-L-cysteine&apos;</deletedAxiom>
<deletedAxiom>&apos;cysteine biosynthetic process via S-sulfo-L-cysteine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;S-sulfo-L-cysteine&apos;) and (&apos;has primary output&apos; some &apos;cysteinium&apos;)</deletedAxiom>
<newAxiom>&apos;cysteine biosynthetic process via S-sulfo-L-cysteine&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;S-sulfo-L-cysteine&apos;</newAxiom>
<newAxiom>&apos;cysteine biosynthetic process via S-sulfo-L-cysteine&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;S-sulfo-L-cysteine&apos;) and (&apos;has primary output&apos; some &apos;cysteinium&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019346</classIRI>
<classLabel>transsulfuration</classLabel>
<deletedAxiom>&apos;transsulfuration&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has intermediate&apos; some &apos;cystathionine&apos;) and (&apos;has primary output&apos; some &apos;cysteine&apos;) and (&apos;has primary input&apos; some &apos;homocysteine&apos;)</deletedAxiom>
<deletedAxiom>&apos;transsulfuration&apos; SubClassOf &apos;has intermediate&apos; some &apos;cystathionine&apos;</deletedAxiom>
<newAxiom>&apos;transsulfuration&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;cystathionine&apos;</newAxiom>
<newAxiom>&apos;transsulfuration&apos; EquivalentTo &apos;metabolic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;cystathionine&apos;) and (&apos;has primary output&apos; some &apos;cysteine&apos;) and (&apos;has primary input&apos; some &apos;homocysteine&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034982</classIRI>
<classLabel>mitochondrial protein processing</classLabel>
<newAxiom>&apos;mitochondrial protein processing&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;mitochondrial protein processing&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032286</classIRI>
<classLabel>central nervous system myelin maintenance</classLabel>
<newAxiom>&apos;central nervous system myelin maintenance&apos; SubClassOf &apos;in taxon&apos; only &apos;Bilateria&apos;</newAxiom>
<newAxiom>&apos;central nervous system myelin maintenance&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Bilateria&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032289</classIRI>
<classLabel>central nervous system myelin formation</classLabel>
<newAxiom>&apos;central nervous system myelin formation&apos; SubClassOf &apos;in taxon&apos; only &apos;Bilateria&apos;</newAxiom>
<newAxiom>&apos;central nervous system myelin formation&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Bilateria&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032291</classIRI>
<classLabel>axon ensheathment in central nervous system</classLabel>
<newAxiom>&apos;axon ensheathment in central nervous system&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Bilateria&apos;</newAxiom>
<newAxiom>&apos;axon ensheathment in central nervous system&apos; SubClassOf &apos;in taxon&apos; only &apos;Bilateria&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032293</classIRI>
<classLabel>non-myelinated axon ensheathment in central nervous system</classLabel>
<newAxiom>&apos;non-myelinated axon ensheathment in central nervous system&apos; SubClassOf &apos;in taxon&apos; only &apos;Bilateria&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071896</classIRI>
<classLabel>protein localization to adherens junction</classLabel>
<deletedAxiom>&apos;protein localization to adherens junction&apos; SubClassOf &apos;protein localization to cell junction&apos;</deletedAxiom>
<newAxiom>&apos;protein localization to adherens junction&apos; SubClassOf &apos;protein localization to cell-cell junction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140053</classIRI>
<classLabel>mitochondrial gene expression</classLabel>
<newAxiom>&apos;mitochondrial gene expression&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;mitochondrial gene expression&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140041</classIRI>
<classLabel>cellular detoxification of methylglyoxal</classLabel>
<newAxiom>&apos;cellular detoxification of methylglyoxal&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;cellular organisms&apos;</newAxiom>
<newAxiom>&apos;cellular detoxification of methylglyoxal&apos; SubClassOf &apos;in taxon&apos; only &apos;cellular organisms&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140040</classIRI>
<classLabel>mitochondrial polycistronic RNA processing</classLabel>
<newAxiom>&apos;mitochondrial polycistronic RNA processing&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007264</classIRI>
<classLabel>small GTPase mediated signal transduction</classLabel>
<deletedAxiom>&apos;small GTPase mediated signal transduction&apos; SubClassOf &apos;mediated_by&apos; some &apos;small GTPase&apos;</deletedAxiom>
<deletedAxiom>&apos;small GTPase mediated signal transduction&apos; EquivalentTo &apos;signal transduction&apos; and (&apos;mediated_by&apos; some &apos;small GTPase&apos;)</deletedAxiom>
<newAxiom>&apos;small GTPase mediated signal transduction&apos; SubClassOf &apos;has causal agent&apos; some &apos;small GTPase&apos;</newAxiom>
<newAxiom>&apos;small GTPase mediated signal transduction&apos; EquivalentTo &apos;signal transduction&apos; and (&apos;has causal agent&apos; some &apos;small GTPase&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046775</classIRI>
<classLabel>suppression by virus of host cytokine production</classLabel>
<deletedAxiom>&apos;suppression by virus of host cytokine production&apos; SubClassOf &apos;suppression of defense response of other organism involved in symbiotic interaction&apos;</deletedAxiom>
<newAxiom>&apos;suppression by virus of host cytokine production&apos; SubClassOf &apos;suppression of host defenses&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032194</classIRI>
<classLabel>ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate</classLabel>
<deletedAxiom>&apos;ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate&apos; SubClassOf &apos;has intermediate&apos; some &apos;3,4-dihydroxy-5-polyprenylbenzoate&apos;</deletedAxiom>
<deletedAxiom>&apos;ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;3,4-dihydroxy-5-polyprenylbenzoate&apos;) and (&apos;has primary output&apos; some &apos;ubiquinones&apos;)</deletedAxiom>
<newAxiom>&apos;ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;3,4-dihydroxy-5-polyprenylbenzoate&apos;</newAxiom>
<newAxiom>&apos;ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;3,4-dihydroxy-5-polyprenylbenzoate&apos;) and (&apos;has primary output&apos; some &apos;ubiquinones&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032193</classIRI>
<classLabel>ubiquinone biosynthetic process via 2-polyprenylphenol</classLabel>
<deletedAxiom>&apos;ubiquinone biosynthetic process via 2-polyprenylphenol&apos; SubClassOf &apos;has intermediate&apos; some &apos;2-polyprenylphenol&apos;</deletedAxiom>
<deletedAxiom>&apos;ubiquinone biosynthetic process via 2-polyprenylphenol&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;2-polyprenylphenol&apos;) and (&apos;has primary output&apos; some &apos;ubiquinones&apos;)</deletedAxiom>
<newAxiom>&apos;ubiquinone biosynthetic process via 2-polyprenylphenol&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;2-polyprenylphenol&apos;</newAxiom>
<newAxiom>&apos;ubiquinone biosynthetic process via 2-polyprenylphenol&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;2-polyprenylphenol&apos;) and (&apos;has primary output&apos; some &apos;ubiquinones&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007044</classIRI>
<classLabel>cell-substrate junction assembly</classLabel>
<deletedAxiom>&apos;cell-substrate junction assembly&apos; EquivalentTo &apos;cellular component assembly&apos; and (&apos;results in assembly of&apos; some &apos;cell-substrate junction&apos;)</deletedAxiom>
<newAxiom>&apos;cell-substrate junction assembly&apos; EquivalentTo &apos;cell junction assembly&apos; and (&apos;results in assembly of&apos; some &apos;cell-substrate junction&apos;)</newAxiom>
<newAxiom>&apos;cell-substrate junction assembly&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0150115</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007043</classIRI>
<classLabel>cell-cell junction assembly</classLabel>
<deletedAxiom>&apos;cell-cell junction assembly&apos; EquivalentTo &apos;cellular component assembly&apos; and (&apos;results in assembly of&apos; some &apos;cell-cell junction&apos;)</deletedAxiom>
<newAxiom>&apos;cell-cell junction assembly&apos; EquivalentTo &apos;cell junction assembly&apos; and (&apos;results in assembly of&apos; some &apos;cell-cell junction&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007045</classIRI>
<classLabel>cell-substrate adherens junction assembly</classLabel>
<deletedAxiom>&apos;cell-substrate adherens junction assembly&apos; SubClassOf &apos;cell-substrate junction assembly&apos;</deletedAxiom>
<deletedAxiom>&apos;cell-substrate adherens junction assembly&apos; EquivalentTo &apos;cellular component assembly&apos; and (&apos;results in assembly of&apos; some &apos;cell-substrate adherens junction&apos;)</deletedAxiom>
<deletedAxiom>&apos;cell-substrate adherens junction assembly&apos; SubClassOf &apos;adherens junction assembly&apos;</deletedAxiom>
<deletedAxiom>&apos;cell-substrate adherens junction assembly&apos; SubClassOf &apos;results in assembly of&apos; some &apos;cell-substrate adherens junction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032042</classIRI>
<classLabel>mitochondrial DNA metabolic process</classLabel>
<newAxiom>&apos;mitochondrial DNA metabolic process&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;mitochondrial DNA metabolic process&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032043</classIRI>
<classLabel>mitochondrial DNA catabolic process</classLabel>
<newAxiom>&apos;mitochondrial DNA catabolic process&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007006</classIRI>
<classLabel>mitochondrial membrane organization</classLabel>
<newAxiom>&apos;mitochondrial membrane organization&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;mitochondrial membrane organization&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007018</classIRI>
<classLabel>microtubule-based movement</classLabel>
<deletedAxiom>&apos;microtubule-based movement&apos; SubClassOf &apos;mediated_by&apos; some &apos;microtubule&apos;</deletedAxiom>
<deletedAxiom>&apos;microtubule-based movement&apos; EquivalentTo &apos;movement of cell or subcellular component&apos; and (&apos;mediated_by&apos; some &apos;microtubule&apos;)</deletedAxiom>
<newAxiom>&apos;microtubule-based movement&apos; EquivalentTo &apos;movement of cell or subcellular component&apos; and (&apos;has causal agent&apos; some &apos;microtubule&apos;)</newAxiom>
<newAxiom>&apos;microtubule-based movement&apos; SubClassOf &apos;has causal agent&apos; some &apos;microtubule&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071434</classIRI>
<classLabel>cell chemotaxis to angiotensin</classLabel>
<deletedAxiom>&apos;cell chemotaxis to angiotensin&apos; EquivalentTo &apos;cell chemotaxis&apos; and (&apos;mediated_by&apos; some &apos;angiotensin&apos;)</deletedAxiom>
<deletedAxiom>&apos;cell chemotaxis to angiotensin&apos; SubClassOf &apos;mediated_by&apos; some &apos;angiotensin&apos;</deletedAxiom>
<newAxiom>&apos;cell chemotaxis to angiotensin&apos; SubClassOf &apos;has causal agent&apos; some &apos;angiotensin&apos;</newAxiom>
<newAxiom>&apos;cell chemotaxis to angiotensin&apos; EquivalentTo &apos;cell chemotaxis&apos; and (&apos;has causal agent&apos; some &apos;angiotensin&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061832</classIRI>
<classLabel>basal ectoplasmic specialization</classLabel>
<deletedAxiom>&apos;basal ectoplasmic specialization&apos; SubClassOf &apos;cell-cell adherens junction&apos;</deletedAxiom>
<newAxiom>&apos;basal ectoplasmic specialization&apos; SubClassOf &apos;cell-cell junction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061831</classIRI>
<classLabel>apical ectoplasmic specialization</classLabel>
<deletedAxiom>&apos;apical ectoplasmic specialization&apos; SubClassOf &apos;cell-cell adherens junction&apos;</deletedAxiom>
<newAxiom>&apos;apical ectoplasmic specialization&apos; SubClassOf &apos;cell-cell junction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071027</classIRI>
<classLabel>nuclear RNA surveillance</classLabel>
<newAxiom>&apos;nuclear RNA surveillance&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;nuclear RNA surveillance&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022010</classIRI>
<classLabel>central nervous system myelination</classLabel>
<newAxiom>&apos;central nervous system myelination&apos; SubClassOf &apos;in taxon&apos; only &apos;Bilateria&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061612</classIRI>
<classLabel>galactose to glucose-1-phosphate metabolic process</classLabel>
<deletedAxiom>&apos;galactose to glucose-1-phosphate metabolic process&apos; SubClassOf &apos;has intermediate&apos; some &apos;UDP-D-galactose&apos;</deletedAxiom>
<deletedAxiom>&apos;galactose to glucose-1-phosphate metabolic process&apos; EquivalentTo &apos;galactose metabolic process&apos; and (&apos;has intermediate&apos; some &apos;UDP-D-galactose&apos;) and (&apos;starts with&apos; some &apos;galactokinase activity&apos;) and (&apos;ends with&apos; some &apos;UTP:galactose-1-phosphate uridylyltransferase activity&apos;) and (&apos;has primary input&apos; some &apos;galactose&apos;)</deletedAxiom>
<newAxiom>&apos;galactose to glucose-1-phosphate metabolic process&apos; EquivalentTo &apos;galactose metabolic process&apos; and (&apos;starts with&apos; some &apos;galactokinase activity&apos;) and (&apos;ends with&apos; some &apos;UTP:galactose-1-phosphate uridylyltransferase activity&apos;) and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;UDP-D-galactose&apos;) and (&apos;has primary input&apos; some &apos;galactose&apos;)</newAxiom>
<newAxiom>&apos;galactose to glucose-1-phosphate metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;UDP-D-galactose&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061620</classIRI>
<classLabel>glycolytic process through glucose-6-phosphate</classLabel>
<deletedAxiom>&apos;glycolytic process through glucose-6-phosphate&apos; SubClassOf &apos;has intermediate&apos; some &apos;D-glucose 6-phosphate&apos;</deletedAxiom>
<deletedAxiom>&apos;glycolytic process through glucose-6-phosphate&apos; EquivalentTo &apos;glycolytic process through fructose-6-phosphate&apos; and (&apos;has_part&apos; some &apos;glucose-6-phosphate isomerase activity&apos;) and (&apos;has intermediate&apos; some &apos;D-glucose 6-phosphate&apos;)</deletedAxiom>
<newAxiom>&apos;glycolytic process through glucose-6-phosphate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;D-glucose 6-phosphate&apos;</newAxiom>
<newAxiom>&apos;glycolytic process through glucose-6-phosphate&apos; EquivalentTo &apos;glycolytic process through fructose-6-phosphate&apos; and (&apos;has_part&apos; some &apos;glucose-6-phosphate isomerase activity&apos;) and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;D-glucose 6-phosphate&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061679</classIRI>
<classLabel>Entner-Doudoroff pathway through gluconate</classLabel>
<deletedAxiom>&apos;Entner-Doudoroff pathway through gluconate&apos; SubClassOf &apos;has intermediate&apos; some &apos;D-gluconate&apos;</deletedAxiom>
<deletedAxiom>&apos;Entner-Doudoroff pathway through gluconate&apos; EquivalentTo &apos;Entner-Doudoroff pathway&apos; and (&apos;has_part&apos; some &apos;gluconate dehydratase activity&apos;) and (&apos;has_part&apos; some &apos;glucose 1-dehydrogenase (NADP+) activity&apos;) and (&apos;has intermediate&apos; some &apos;D-gluconate&apos;) and (&apos;has output&apos; some &apos;pyruvate&apos;)</deletedAxiom>
<newAxiom>&apos;Entner-Doudoroff pathway through gluconate&apos; EquivalentTo &apos;Entner-Doudoroff pathway&apos; and (&apos;has_part&apos; some &apos;gluconate dehydratase activity&apos;) and (&apos;has_part&apos; some &apos;glucose 1-dehydrogenase (NADP+) activity&apos;) and (&apos;has output&apos; some &apos;pyruvate&apos;) and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;D-gluconate&apos;)</newAxiom>
<newAxiom>&apos;Entner-Doudoroff pathway through gluconate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;D-gluconate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036523</classIRI>
<classLabel>positive regulation by symbiont of host cytokine secretion</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host cytokine secretion&apos; SubClassOf &apos;modulation by symbiont of host cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host cytokine secretion&apos; SubClassOf &apos;positive regulation by symbiont of host innate immune response&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation by symbiont of host cytokine secretion&apos; SubClassOf &apos;induction by symbiont of host innate immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061466</classIRI>
<classLabel>plasma membrane part of cell junction</classLabel>
<deletedAxiom>&apos;plasma membrane part of cell junction&apos; SubClassOf &apos;part of&apos; some &apos;cell junction&apos;</deletedAxiom>
<deletedAxiom>&apos;plasma membrane part of cell junction&apos; SubClassOf &apos;part of&apos; some &apos;plasma membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;plasma membrane part of cell junction&apos; SubClassOf &apos;cellular anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061465</classIRI>
<classLabel>plasma membrane part of hemidesmosome</classLabel>
<deletedAxiom>&apos;plasma membrane part of hemidesmosome&apos; SubClassOf &apos;plasma membrane part of cell-substrate junction.&apos;</deletedAxiom>
<deletedAxiom>&apos;plasma membrane part of hemidesmosome&apos; SubClassOf &apos;part of&apos; some &apos;hemidesmosome&apos;</deletedAxiom>
<deletedAxiom>&apos;plasma membrane part of hemidesmosome&apos; SubClassOf &apos;part of&apos; some &apos;basal plasma membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061464</classIRI>
<classLabel>plasma membrane part of cell-substrate junction.</classLabel>
<deletedAxiom>&apos;plasma membrane part of cell-substrate junction.&apos; SubClassOf &apos;cellular anatomical entity&apos;</deletedAxiom>
<deletedAxiom>&apos;plasma membrane part of cell-substrate junction.&apos; SubClassOf &apos;part of&apos; some &apos;plasma membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;plasma membrane part of cell-substrate junction.&apos; SubClassOf &apos;part of&apos; some &apos;cell-substrate junction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120184</classIRI>
<classLabel>negative regulation of focal adhesion disassembly</classLabel>
<deletedAxiom>&apos;negative regulation of focal adhesion disassembly&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;focal adhesion disassembly&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of focal adhesion disassembly&apos; SubClassOf &apos;negative regulation of adherens junction organization&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of focal adhesion disassembly&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;focal adhesion disassembly&apos;)</newAxiom>
<newAxiom>&apos;negative regulation of focal adhesion disassembly&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0150118</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120183</classIRI>
<classLabel>positive regulation of focal adhesion disassembly</classLabel>
<deletedAxiom>&apos;positive regulation of focal adhesion disassembly&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;focal adhesion disassembly&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of focal adhesion disassembly&apos; SubClassOf &apos;positive regulation of adherens junction organization&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of focal adhesion disassembly&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;focal adhesion disassembly&apos;)</newAxiom>
<newAxiom>&apos;positive regulation of focal adhesion disassembly&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0150117</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120182</classIRI>
<classLabel>regulation of focal adhesion disassembly</classLabel>
<deletedAxiom>&apos;regulation of focal adhesion disassembly&apos; SubClassOf &apos;regulation of adherens junction organization&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of focal adhesion disassembly&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;focal adhesion disassembly&apos;)</deletedAxiom>
<newAxiom>&apos;regulation of focal adhesion disassembly&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0150116</newAxiom>
<newAxiom>&apos;regulation of focal adhesion disassembly&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;focal adhesion disassembly&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120180</classIRI>
<classLabel>cell-substrate adherens junction disassembly</classLabel>
<deletedAxiom>&apos;cell-substrate adherens junction disassembly&apos; SubClassOf &apos;adherens junction disassembly&apos;</deletedAxiom>
<deletedAxiom>&apos;cell-substrate adherens junction disassembly&apos; EquivalentTo &apos;cellular component disassembly&apos; and (&apos;results in disassembly of&apos; some &apos;cell-substrate adherens junction&apos;)</deletedAxiom>
<deletedAxiom>&apos;cell-substrate adherens junction disassembly&apos; SubClassOf &apos;results in disassembly of&apos; some &apos;cell-substrate adherens junction&apos;</deletedAxiom>
<newAxiom>&apos;cell-substrate adherens junction disassembly&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0150115</newAxiom>
<newAxiom>&apos;cell-substrate adherens junction disassembly&apos; SubClassOf &apos;results in disassembly of&apos; some &apos;cell-substrate junction&apos;</newAxiom>
<newAxiom>&apos;cell-substrate adherens junction disassembly&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0150146</newAxiom>
<newAxiom>&apos;cell-substrate adherens junction disassembly&apos; EquivalentTo http://purl.obolibrary.org/obo/GO_0150146 and (&apos;results in disassembly of&apos; some &apos;cell-substrate junction&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120179</classIRI>
<classLabel>adherens junction disassembly</classLabel>
<deletedAxiom>&apos;adherens junction disassembly&apos; SubClassOf &apos;cellular component disassembly&apos;</deletedAxiom>
<deletedAxiom>&apos;adherens junction disassembly&apos; EquivalentTo &apos;cellular component disassembly&apos; and (&apos;results in disassembly of&apos; some &apos;adherens junction&apos;)</deletedAxiom>
<newAxiom>&apos;adherens junction disassembly&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0150147</newAxiom>
<newAxiom>&apos;adherens junction disassembly&apos; EquivalentTo http://purl.obolibrary.org/obo/GO_0150147 and (&apos;results in disassembly of&apos; some &apos;adherens junction&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120145</classIRI>
<classLabel>protein localization to basal ectoplasmic specialization</classLabel>
<deletedAxiom>&apos;protein localization to basal ectoplasmic specialization&apos; SubClassOf &apos;protein localization to cell-cell adherens junction&apos;</deletedAxiom>
<newAxiom>&apos;protein localization to basal ectoplasmic specialization&apos; SubClassOf &apos;protein localization to cell-cell junction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051975</classIRI>
<classLabel>lysine biosynthetic process via alpha-aminoadipate and saccharopine</classLabel>
<deletedAxiom>&apos;lysine biosynthetic process via alpha-aminoadipate and saccharopine&apos; SubClassOf &apos;has intermediate&apos; some &apos;L-saccharopine&apos;</deletedAxiom>
<deletedAxiom>&apos;lysine biosynthetic process via alpha-aminoadipate and saccharopine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;L-saccharopine&apos;) and (&apos;has intermediate&apos; some &apos;2-aminoadipic acid&apos;) and (&apos;has primary output&apos; some &apos;lysinate&apos;)</deletedAxiom>
<deletedAxiom>&apos;lysine biosynthetic process via alpha-aminoadipate and saccharopine&apos; SubClassOf &apos;has intermediate&apos; some &apos;2-aminoadipic acid&apos;</deletedAxiom>
<newAxiom>&apos;lysine biosynthetic process via alpha-aminoadipate and saccharopine&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;2-aminoadipic acid&apos;</newAxiom>
<newAxiom>&apos;lysine biosynthetic process via alpha-aminoadipate and saccharopine&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;L-saccharopine&apos;</newAxiom>
<newAxiom>&apos;lysine biosynthetic process via alpha-aminoadipate and saccharopine&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;L-saccharopine&apos;) and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;2-aminoadipic acid&apos;) and (&apos;has primary output&apos; some &apos;lysinate&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051976</classIRI>
<classLabel>lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate</classLabel>
<deletedAxiom>&apos;lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate&apos; SubClassOf &apos;has intermediate&apos; some &apos;2-aminoadipic acid&apos;</deletedAxiom>
<deletedAxiom>&apos;lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate&apos; SubClassOf &apos;has intermediate&apos; some &apos;N-acetyl-L-2-aminoadipate(2-)&apos;</deletedAxiom>
<deletedAxiom>&apos;lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;2-aminoadipic acid&apos;) and (&apos;has intermediate&apos; some &apos;N-acetyl-L-2-aminoadipate(2-)&apos;) and (&apos;has primary output&apos; some &apos;lysinate&apos;)</deletedAxiom>
<newAxiom>&apos;lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;N-acetyl-L-2-aminoadipate(2-)&apos;</newAxiom>
<newAxiom>&apos;lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;2-aminoadipic acid&apos;) and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;N-acetyl-L-2-aminoadipate(2-)&apos;) and (&apos;has primary output&apos; some &apos;lysinate&apos;)</newAxiom>
<newAxiom>&apos;lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;2-aminoadipic acid&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051894</classIRI>
<classLabel>positive regulation of focal adhesion assembly</classLabel>
<deletedAxiom>&apos;positive regulation of focal adhesion assembly&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;focal adhesion assembly&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of focal adhesion assembly&apos; SubClassOf &apos;positive regulation of adherens junction organization&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of focal adhesion assembly&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0150117</newAxiom>
<newAxiom>&apos;positive regulation of focal adhesion assembly&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;focal adhesion assembly&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051893</classIRI>
<classLabel>regulation of focal adhesion assembly</classLabel>
<deletedAxiom>&apos;regulation of focal adhesion assembly&apos; SubClassOf &apos;regulation of adherens junction organization&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of focal adhesion assembly&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;focal adhesion assembly&apos;)</deletedAxiom>
<newAxiom>&apos;regulation of focal adhesion assembly&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;focal adhesion assembly&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051895</classIRI>
<classLabel>negative regulation of focal adhesion assembly</classLabel>
<deletedAxiom>&apos;negative regulation of focal adhesion assembly&apos; SubClassOf &apos;negative regulation of adherens junction organization&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of focal adhesion assembly&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;focal adhesion assembly&apos;)</deletedAxiom>
<newAxiom>&apos;negative regulation of focal adhesion assembly&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;focal adhesion assembly&apos;)</newAxiom>
<newAxiom>&apos;negative regulation of focal adhesion assembly&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0150118</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051832</classIRI>
<classLabel>evasion or tolerance of defenses of other organism</classLabel>
<deletedAxiom>&apos;evasion or tolerance of defenses of other organism&apos; SubClassOf &apos;response to defenses of other organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051882</classIRI>
<classLabel>mitochondrial depolarization</classLabel>
<newAxiom>&apos;mitochondrial depolarization&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;mitochondrial depolarization&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099638</classIRI>
<classLabel>endosome to plasma membrane protein transport</classLabel>
<deletedAxiom>&apos;endosome to plasma membrane protein transport&apos; EquivalentTo &apos;protein transport&apos; and (&apos;mediated_by&apos; some &apos;vesicle&apos;) and (&apos;has target start location&apos; some &apos;endosome&apos;) and (&apos;has target end location&apos; some &apos;plasma membrane&apos;)</deletedAxiom>
<newAxiom>&apos;endosome to plasma membrane protein transport&apos; EquivalentTo &apos;protein transport&apos; and (&apos;has target start location&apos; some &apos;endosome&apos;) and (&apos;has target end location&apos; some &apos;plasma membrane&apos;) and (&apos;has causal agent&apos; some &apos;vesicle&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099639</classIRI>
<classLabel>neurotransmitter receptor transport, endosome to plasma membrane</classLabel>
<deletedAxiom>&apos;neurotransmitter receptor transport, endosome to plasma membrane&apos; EquivalentTo &apos;protein transport&apos; and (&apos;mediated_by&apos; some &apos;vesicle&apos;) and (&apos;transports or maintains localization of&apos; some &apos;neurotransmitter receptor complex&apos;) and (&apos;has target start location&apos; some &apos;endosome&apos;) and (&apos;has target end location&apos; some &apos;plasma membrane&apos;)</deletedAxiom>
<newAxiom>&apos;neurotransmitter receptor transport, endosome to plasma membrane&apos; EquivalentTo &apos;protein transport&apos; and (&apos;transports or maintains localization of&apos; some &apos;neurotransmitter receptor complex&apos;) and (&apos;has target start location&apos; some &apos;endosome&apos;) and (&apos;has target end location&apos; some &apos;plasma membrane&apos;) and (&apos;has causal agent&apos; some &apos;vesicle&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099643</classIRI>
<classLabel>signal release from synapse</classLabel>
<newAxiom>&apos;signal release from synapse&apos; SubClassOf &apos;in taxon&apos; only &apos;Metazoa&apos;</newAxiom>
<newAxiom>&apos;signal release from synapse&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Metazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099646</classIRI>
<classLabel>neurotransmitter receptor transport, plasma membrane to endosome</classLabel>
<deletedAxiom>&apos;neurotransmitter receptor transport, plasma membrane to endosome&apos; EquivalentTo &apos;protein transport&apos; and (&apos;mediated_by&apos; some &apos;vesicle&apos;) and (&apos;has start location&apos; some &apos;plasma membrane&apos;) and (&apos;transports or maintains localization of&apos; some &apos;neurotransmitter receptor complex&apos;) and (&apos;has target end location&apos; some &apos;endosome&apos;)</deletedAxiom>
<newAxiom>&apos;neurotransmitter receptor transport, plasma membrane to endosome&apos; EquivalentTo &apos;protein transport&apos; and (&apos;has start location&apos; some &apos;plasma membrane&apos;) and (&apos;transports or maintains localization of&apos; some &apos;neurotransmitter receptor complex&apos;) and (&apos;has target end location&apos; some &apos;endosome&apos;) and (&apos;has causal agent&apos; some &apos;vesicle&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0085034</classIRI>
<classLabel>negative regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade</classLabel>
<newAxiom>&apos;negative regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade&apos; SubClassOf &apos;negative regulation by symbiont of host signal transduction pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0085027</classIRI>
<classLabel>entry into host via enzymatic degradation of host anatomical structure</classLabel>
<deletedAxiom>&apos;entry into host via enzymatic degradation of host anatomical structure&apos; SubClassOf &apos;entry into host through host barriers&apos;</deletedAxiom>
<newAxiom>&apos;entry into host via enzymatic degradation of host anatomical structure&apos; SubClassOf &apos;entry into host&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051608</classIRI>
<classLabel>histamine transport</classLabel>
<deletedAxiom>&apos;histamine transport&apos; SubClassOf &apos;azole transport&apos;</deletedAxiom>
<newAxiom>&apos;histamine transport&apos; SubClassOf &apos;organic substance transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036008</classIRI>
<classLabel>sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate</classLabel>
<deletedAxiom>&apos;sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate&apos; SubClassOf &apos;has intermediate&apos; some &apos;fructose&apos;</deletedAxiom>
<deletedAxiom>&apos;sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has_part&apos; some &apos;fructokinase activity&apos;) and (&apos;has_part&apos; some &apos;sucrose-phosphate phosphatase activity&apos;) and (&apos;has intermediate&apos; some &apos;fructose&apos;) and (&apos;starts with&apos; some &apos;protein-N(PI)-phosphohistidine-sucrose phosphotransferase system transporter activity&apos;) and (&apos;has primary output&apos; some &apos;D-glucose 6-phosphate&apos;) and (&apos;has primary output&apos; some &apos;keto-D-fructose 6-phosphate&apos;) and (&apos;has primary input&apos; some &apos;sucrose&apos;)</deletedAxiom>
<newAxiom>&apos;sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has_part&apos; some &apos;fructokinase activity&apos;) and (&apos;has_part&apos; some &apos;sucrose-phosphate phosphatase activity&apos;) and (&apos;starts with&apos; some &apos;protein-N(PI)-phosphohistidine-sucrose phosphotransferase system transporter activity&apos;) and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;fructose&apos;) and (&apos;has primary output&apos; some &apos;D-glucose 6-phosphate&apos;) and (&apos;has primary output&apos; some &apos;keto-D-fructose 6-phosphate&apos;) and (&apos;has primary input&apos; some &apos;sucrose&apos;)</newAxiom>
<newAxiom>&apos;sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;fructose&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051649</classIRI>
<classLabel>establishment of localization in cell</classLabel>
<newAxiom>&apos;establishment of localization in cell&apos; SubClassOf &apos;in taxon&apos; only &apos;cellular organisms&apos;</newAxiom>
<newAxiom>&apos;establishment of localization in cell&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;cellular organisms&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051560</classIRI>
<classLabel>mitochondrial calcium ion homeostasis</classLabel>
<newAxiom>&apos;mitochondrial calcium ion homeostasis&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;mitochondrial calcium ion homeostasis&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099538</classIRI>
<classLabel>synaptic signaling via neuropeptide</classLabel>
<deletedAxiom>&apos;synaptic signaling via neuropeptide&apos; EquivalentTo &apos;synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;peptide&apos;)</deletedAxiom>
<deletedAxiom>&apos;synaptic signaling via neuropeptide&apos; SubClassOf &apos;mediated_by&apos; some &apos;peptide&apos;</deletedAxiom>
<newAxiom>&apos;synaptic signaling via neuropeptide&apos; SubClassOf &apos;has causal agent&apos; some &apos;peptide&apos;</newAxiom>
<newAxiom>&apos;synaptic signaling via neuropeptide&apos; EquivalentTo &apos;synaptic signaling&apos; and (&apos;has causal agent&apos; some &apos;peptide&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099540</classIRI>
<classLabel>trans-synaptic signaling by neuropeptide</classLabel>
<deletedAxiom>&apos;trans-synaptic signaling by neuropeptide&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;peptide&apos;)</deletedAxiom>
<newAxiom>&apos;trans-synaptic signaling by neuropeptide&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;has causal agent&apos; some &apos;peptide&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099542</classIRI>
<classLabel>trans-synaptic signaling by endocannabinoid</classLabel>
<deletedAxiom>&apos;trans-synaptic signaling by endocannabinoid&apos; SubClassOf &apos;mediated_by&apos; some &apos;cannabinoid&apos;</deletedAxiom>
<deletedAxiom>&apos;trans-synaptic signaling by endocannabinoid&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;cannabinoid&apos;)</deletedAxiom>
<newAxiom>&apos;trans-synaptic signaling by endocannabinoid&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;has causal agent&apos; some &apos;cannabinoid&apos;)</newAxiom>
<newAxiom>&apos;trans-synaptic signaling by endocannabinoid&apos; SubClassOf &apos;has causal agent&apos; some &apos;cannabinoid&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099541</classIRI>
<classLabel>trans-synaptic signaling by lipid</classLabel>
<deletedAxiom>&apos;trans-synaptic signaling by lipid&apos; SubClassOf &apos;mediated_by&apos; some &apos;lipid&apos;</deletedAxiom>
<deletedAxiom>&apos;trans-synaptic signaling by lipid&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;lipid&apos;)</deletedAxiom>
<newAxiom>&apos;trans-synaptic signaling by lipid&apos; SubClassOf &apos;has causal agent&apos; some &apos;lipid&apos;</newAxiom>
<newAxiom>&apos;trans-synaptic signaling by lipid&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;has causal agent&apos; some &apos;lipid&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099546</classIRI>
<classLabel>protein catabolic process, modulating synaptic transmission</classLabel>
<newAxiom>&apos;protein catabolic process, modulating synaptic transmission&apos; SubClassOf &apos;in taxon&apos; only &apos;Metazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099545</classIRI>
<classLabel>trans-synaptic signaling by trans-synaptic complex</classLabel>
<deletedAxiom>&apos;trans-synaptic signaling by trans-synaptic complex&apos; SubClassOf &apos;mediated_by&apos; some &apos;trans-synaptic protein complex&apos;</deletedAxiom>
<deletedAxiom>&apos;trans-synaptic signaling by trans-synaptic complex&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;trans-synaptic protein complex&apos;)</deletedAxiom>
<newAxiom>&apos;trans-synaptic signaling by trans-synaptic complex&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;has causal agent&apos; some &apos;trans-synaptic protein complex&apos;)</newAxiom>
<newAxiom>&apos;trans-synaptic signaling by trans-synaptic complex&apos; SubClassOf &apos;has causal agent&apos; some &apos;trans-synaptic protein complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099548</classIRI>
<classLabel>trans-synaptic signaling by nitric oxide</classLabel>
<deletedAxiom>&apos;trans-synaptic signaling by nitric oxide&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;nitric oxide&apos;)</deletedAxiom>
<newAxiom>&apos;trans-synaptic signaling by nitric oxide&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;has causal agent&apos; some &apos;nitric oxide&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099547</classIRI>
<classLabel>regulation of translation at synapse, modulating synaptic transmission</classLabel>
<newAxiom>&apos;regulation of translation at synapse, modulating synaptic transmission&apos; SubClassOf &apos;in taxon&apos; only &apos;Metazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099549</classIRI>
<classLabel>trans-synaptic signaling by carbon monoxide</classLabel>
<deletedAxiom>&apos;trans-synaptic signaling by carbon monoxide&apos; SubClassOf &apos;mediated_by&apos; some &apos;carbon monoxide&apos;</deletedAxiom>
<deletedAxiom>&apos;trans-synaptic signaling by carbon monoxide&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;carbon monoxide&apos;)</deletedAxiom>
<newAxiom>&apos;trans-synaptic signaling by carbon monoxide&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;has causal agent&apos; some &apos;carbon monoxide&apos;)</newAxiom>
<newAxiom>&apos;trans-synaptic signaling by carbon monoxide&apos; SubClassOf &apos;has causal agent&apos; some &apos;carbon monoxide&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099551</classIRI>
<classLabel>trans-synaptic signaling by neuropeptide, modulating synaptic transmission</classLabel>
<deletedAxiom>&apos;trans-synaptic signaling by neuropeptide, modulating synaptic transmission&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;peptide&apos;) and (&apos;regulates&apos; some &apos;chemical synaptic transmission&apos;)</deletedAxiom>
<newAxiom>&apos;trans-synaptic signaling by neuropeptide, modulating synaptic transmission&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;regulates&apos; some &apos;chemical synaptic transmission&apos;) and (&apos;has causal agent&apos; some &apos;peptide&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099553</classIRI>
<classLabel>trans-synaptic signaling by endocannabinoid, modulating synaptic transmission</classLabel>
<deletedAxiom>&apos;trans-synaptic signaling by endocannabinoid, modulating synaptic transmission&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;cannabinoid&apos;) and (&apos;regulates&apos; some &apos;chemical synaptic transmission&apos;)</deletedAxiom>
<newAxiom>&apos;trans-synaptic signaling by endocannabinoid, modulating synaptic transmission&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;regulates&apos; some &apos;chemical synaptic transmission&apos;) and (&apos;has causal agent&apos; some &apos;cannabinoid&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099552</classIRI>
<classLabel>trans-synaptic signaling by lipid, modulating synaptic transmission</classLabel>
<deletedAxiom>&apos;trans-synaptic signaling by lipid, modulating synaptic transmission&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;lipid&apos;) and (&apos;regulates&apos; some &apos;chemical synaptic transmission&apos;)</deletedAxiom>
<newAxiom>&apos;trans-synaptic signaling by lipid, modulating synaptic transmission&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;regulates&apos; some &apos;chemical synaptic transmission&apos;) and (&apos;has causal agent&apos; some &apos;lipid&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099555</classIRI>
<classLabel>trans-synaptic signaling by nitric oxide, modulating synaptic transmission</classLabel>
<deletedAxiom>&apos;trans-synaptic signaling by nitric oxide, modulating synaptic transmission&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;nitric oxide&apos;) and (&apos;regulates&apos; some &apos;chemical synaptic transmission&apos;)</deletedAxiom>
<newAxiom>&apos;trans-synaptic signaling by nitric oxide, modulating synaptic transmission&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;regulates&apos; some &apos;chemical synaptic transmission&apos;) and (&apos;has causal agent&apos; some &apos;nitric oxide&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099557</classIRI>
<classLabel>trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission</classLabel>
<deletedAxiom>&apos;trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;trans-synaptic protein complex&apos;) and (&apos;regulates&apos; some &apos;chemical synaptic transmission&apos;)</deletedAxiom>
<newAxiom>&apos;trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;regulates&apos; some &apos;chemical synaptic transmission&apos;) and (&apos;has causal agent&apos; some &apos;trans-synaptic protein complex&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099556</classIRI>
<classLabel>trans-synaptic signaling by carbon monoxide, modulating synaptic transmission</classLabel>
<deletedAxiom>&apos;trans-synaptic signaling by carbon monoxide, modulating synaptic transmission&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;carbon monoxide&apos;) and (&apos;regulates&apos; some &apos;chemical synaptic transmission&apos;)</deletedAxiom>
<newAxiom>&apos;trans-synaptic signaling by carbon monoxide, modulating synaptic transmission&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;regulates&apos; some &apos;chemical synaptic transmission&apos;) and (&apos;has causal agent&apos; some &apos;carbon monoxide&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099574</classIRI>
<classLabel>regulation of protein catabolic process at synapse, modulating synaptic transmission</classLabel>
<newAxiom>&apos;regulation of protein catabolic process at synapse, modulating synaptic transmission&apos; SubClassOf &apos;in taxon&apos; only &apos;Metazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051415</classIRI>
<classLabel>microtubule nucleation by interphase microtubule organizing center</classLabel>
<deletedAxiom>&apos;microtubule nucleation by interphase microtubule organizing center&apos; SubClassOf &apos;mediated_by&apos; some &apos;interphase microtubule organizing center&apos;</deletedAxiom>
<newAxiom>&apos;microtubule nucleation by interphase microtubule organizing center&apos; SubClassOf &apos;has causal agent&apos; some &apos;interphase microtubule organizing center&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051418</classIRI>
<classLabel>microtubule nucleation by microtubule organizing center</classLabel>
<deletedAxiom>&apos;microtubule nucleation by microtubule organizing center&apos; SubClassOf &apos;mediated_by&apos; some &apos;microtubule organizing center&apos;</deletedAxiom>
<deletedAxiom>&apos;microtubule nucleation by microtubule organizing center&apos; EquivalentTo &apos;microtubule nucleation&apos; and (&apos;mediated_by&apos; some &apos;microtubule organizing center&apos;)</deletedAxiom>
<newAxiom>&apos;microtubule nucleation by microtubule organizing center&apos; SubClassOf &apos;has causal agent&apos; some &apos;microtubule organizing center&apos;</newAxiom>
<newAxiom>&apos;microtubule nucleation by microtubule organizing center&apos; EquivalentTo &apos;microtubule nucleation&apos; and (&apos;has causal agent&apos; some &apos;microtubule organizing center&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051417</classIRI>
<classLabel>microtubule nucleation by spindle pole body</classLabel>
<deletedAxiom>&apos;microtubule nucleation by spindle pole body&apos; EquivalentTo &apos;microtubule nucleation&apos; and (&apos;mediated_by&apos; some &apos;spindle pole body&apos;)</deletedAxiom>
<deletedAxiom>&apos;microtubule nucleation by spindle pole body&apos; SubClassOf &apos;mediated_by&apos; some &apos;spindle pole body&apos;</deletedAxiom>
<newAxiom>&apos;microtubule nucleation by spindle pole body&apos; EquivalentTo &apos;microtubule nucleation&apos; and (&apos;has causal agent&apos; some &apos;spindle pole body&apos;)</newAxiom>
<newAxiom>&apos;microtubule nucleation by spindle pole body&apos; SubClassOf &apos;has causal agent&apos; some &apos;spindle pole body&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051457</classIRI>
<classLabel>maintenance of protein location in nucleus</classLabel>
<newAxiom>&apos;maintenance of protein location in nucleus&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;maintenance of protein location in nucleus&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002560</classIRI>
<classLabel>basophil mediated immunity</classLabel>
<deletedAxiom>&apos;basophil mediated immunity&apos; EquivalentTo &apos;immune system process&apos; and (&apos;mediated_by&apos; some &apos;basophil&apos;)</deletedAxiom>
<deletedAxiom>&apos;basophil mediated immunity&apos; SubClassOf &apos;mediated_by&apos; some &apos;basophil&apos;</deletedAxiom>
<newAxiom>&apos;basophil mediated immunity&apos; SubClassOf &apos;has causal agent&apos; some &apos;basophil&apos;</newAxiom>
<newAxiom>&apos;basophil mediated immunity&apos; EquivalentTo &apos;immune system process&apos; and (&apos;has causal agent&apos; some &apos;basophil&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002557</classIRI>
<classLabel>histamine secretion by basophil</classLabel>
<deletedAxiom>&apos;histamine secretion by basophil&apos; EquivalentTo &apos;histamine secretion&apos; and (&apos;mediated_by&apos; some &apos;basophil&apos;)</deletedAxiom>
<deletedAxiom>&apos;histamine secretion by basophil&apos; SubClassOf &apos;mediated_by&apos; some &apos;basophil&apos;</deletedAxiom>
<newAxiom>&apos;histamine secretion by basophil&apos; EquivalentTo &apos;histamine secretion&apos; and (&apos;has causal agent&apos; some &apos;basophil&apos;)</newAxiom>
<newAxiom>&apos;histamine secretion by basophil&apos; SubClassOf &apos;has causal agent&apos; some &apos;basophil&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002556</classIRI>
<classLabel>serotonin secretion by basophil</classLabel>
<deletedAxiom>&apos;serotonin secretion by basophil&apos; SubClassOf &apos;mediated_by&apos; some &apos;basophil&apos;</deletedAxiom>
<deletedAxiom>&apos;serotonin secretion by basophil&apos; EquivalentTo &apos;serotonin secretion&apos; and (&apos;mediated_by&apos; some &apos;basophil&apos;)</deletedAxiom>
<newAxiom>&apos;serotonin secretion by basophil&apos; EquivalentTo &apos;serotonin secretion&apos; and (&apos;has causal agent&apos; some &apos;basophil&apos;)</newAxiom>
<newAxiom>&apos;serotonin secretion by basophil&apos; SubClassOf &apos;has causal agent&apos; some &apos;basophil&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002555</classIRI>
<classLabel>histamine secretion by platelet</classLabel>
<deletedAxiom>&apos;histamine secretion by platelet&apos; EquivalentTo &apos;histamine secretion&apos; and (&apos;mediated_by&apos; some &apos;platelet&apos;)</deletedAxiom>
<deletedAxiom>&apos;histamine secretion by platelet&apos; SubClassOf &apos;mediated_by&apos; some &apos;platelet&apos;</deletedAxiom>
<newAxiom>&apos;histamine secretion by platelet&apos; EquivalentTo &apos;histamine secretion&apos; and (&apos;has causal agent&apos; some &apos;platelet&apos;)</newAxiom>
<newAxiom>&apos;histamine secretion by platelet&apos; SubClassOf &apos;has causal agent&apos; some &apos;platelet&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002554</classIRI>
<classLabel>serotonin secretion by platelet</classLabel>
<deletedAxiom>&apos;serotonin secretion by platelet&apos; EquivalentTo &apos;serotonin secretion&apos; and (&apos;mediated_by&apos; some &apos;platelet&apos;)</deletedAxiom>
<deletedAxiom>&apos;serotonin secretion by platelet&apos; SubClassOf &apos;mediated_by&apos; some &apos;platelet&apos;</deletedAxiom>
<newAxiom>&apos;serotonin secretion by platelet&apos; SubClassOf &apos;has causal agent&apos; some &apos;platelet&apos;</newAxiom>
<newAxiom>&apos;serotonin secretion by platelet&apos; EquivalentTo &apos;serotonin secretion&apos; and (&apos;has causal agent&apos; some &apos;platelet&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002553</classIRI>
<classLabel>histamine secretion by mast cell</classLabel>
<deletedAxiom>&apos;histamine secretion by mast cell&apos; EquivalentTo &apos;histamine secretion&apos; and (&apos;mediated_by&apos; some &apos;mast cell&apos;)</deletedAxiom>
<deletedAxiom>&apos;histamine secretion by mast cell&apos; SubClassOf &apos;mediated_by&apos; some &apos;mast cell&apos;</deletedAxiom>
<newAxiom>&apos;histamine secretion by mast cell&apos; SubClassOf &apos;has causal agent&apos; some &apos;mast cell&apos;</newAxiom>
<newAxiom>&apos;histamine secretion by mast cell&apos; EquivalentTo &apos;histamine secretion&apos; and (&apos;has causal agent&apos; some &apos;mast cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002552</classIRI>
<classLabel>serotonin secretion by mast cell</classLabel>
<deletedAxiom>&apos;serotonin secretion by mast cell&apos; EquivalentTo &apos;serotonin secretion&apos; and (&apos;mediated_by&apos; some &apos;mast cell&apos;)</deletedAxiom>
<deletedAxiom>&apos;serotonin secretion by mast cell&apos; SubClassOf &apos;mediated_by&apos; some &apos;mast cell&apos;</deletedAxiom>
<newAxiom>&apos;serotonin secretion by mast cell&apos; SubClassOf &apos;has causal agent&apos; some &apos;mast cell&apos;</newAxiom>
<newAxiom>&apos;serotonin secretion by mast cell&apos; EquivalentTo &apos;serotonin secretion&apos; and (&apos;has causal agent&apos; some &apos;mast cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904381</classIRI>
<classLabel>Golgi apparatus mannose trimming</classLabel>
<newAxiom>&apos;Golgi apparatus mannose trimming&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;Golgi apparatus mannose trimming&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002499</classIRI>
<classLabel>proteolysis within endosome associated with antigen processing and presentation</classLabel>
<newAxiom>&apos;proteolysis within endosome associated with antigen processing and presentation&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;proteolysis within endosome associated with antigen processing and presentation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051322</classIRI>
<classLabel>anaphase</classLabel>
<newAxiom>&apos;anaphase&apos; SubClassOf &apos;part of&apos; some &apos;M phase&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051305</classIRI>
<classLabel>chromosome movement towards spindle pole</classLabel>
<deletedAxiom>&apos;chromosome movement towards spindle pole&apos; EquivalentTo &apos;establishment of localization in cell&apos; and (&apos;mediated_by&apos; some &apos;microtubule&apos;) and (&apos;transports or maintains localization of&apos; some &apos;chromosome&apos;) and (&apos;has target end location&apos; some &apos;spindle pole&apos;)</deletedAxiom>
<newAxiom>&apos;chromosome movement towards spindle pole&apos; EquivalentTo &apos;establishment of localization in cell&apos; and (&apos;transports or maintains localization of&apos; some &apos;chromosome&apos;) and (&apos;has target end location&apos; some &apos;spindle pole&apos;) and (&apos;has causal agent&apos; some &apos;microtubule&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002456</classIRI>
<classLabel>T cell mediated immunity</classLabel>
<deletedAxiom>&apos;T cell mediated immunity&apos; SubClassOf &apos;mediated_by&apos; some &apos;T cell&apos;</deletedAxiom>
<deletedAxiom>&apos;T cell mediated immunity&apos; EquivalentTo &apos;immune system process&apos; and (&apos;mediated_by&apos; some &apos;T cell&apos;)</deletedAxiom>
<newAxiom>&apos;T cell mediated immunity&apos; SubClassOf &apos;has causal agent&apos; some &apos;T cell&apos;</newAxiom>
<newAxiom>&apos;T cell mediated immunity&apos; EquivalentTo &apos;immune system process&apos; and (&apos;has causal agent&apos; some &apos;T cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002449</classIRI>
<classLabel>lymphocyte mediated immunity</classLabel>
<deletedAxiom>&apos;lymphocyte mediated immunity&apos; EquivalentTo &apos;immune system process&apos; and (&apos;mediated_by&apos; some &apos;lymphocyte&apos;)</deletedAxiom>
<deletedAxiom>&apos;lymphocyte mediated immunity&apos; SubClassOf &apos;mediated_by&apos; some &apos;lymphocyte&apos;</deletedAxiom>
<newAxiom>&apos;lymphocyte mediated immunity&apos; EquivalentTo &apos;immune system process&apos; and (&apos;has causal agent&apos; some &apos;lymphocyte&apos;)</newAxiom>
<newAxiom>&apos;lymphocyte mediated immunity&apos; SubClassOf &apos;has causal agent&apos; some &apos;lymphocyte&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002448</classIRI>
<classLabel>mast cell mediated immunity</classLabel>
<deletedAxiom>&apos;mast cell mediated immunity&apos; SubClassOf &apos;mediated_by&apos; some &apos;mast cell&apos;</deletedAxiom>
<deletedAxiom>&apos;mast cell mediated immunity&apos; EquivalentTo &apos;immune system process&apos; and (&apos;mediated_by&apos; some &apos;mast cell&apos;)</deletedAxiom>
<newAxiom>&apos;mast cell mediated immunity&apos; EquivalentTo &apos;immune system process&apos; and (&apos;has causal agent&apos; some &apos;mast cell&apos;)</newAxiom>
<newAxiom>&apos;mast cell mediated immunity&apos; SubClassOf &apos;has causal agent&apos; some &apos;mast cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002447</classIRI>
<classLabel>eosinophil mediated immunity</classLabel>
<deletedAxiom>&apos;eosinophil mediated immunity&apos; EquivalentTo &apos;immune system process&apos; and (&apos;mediated_by&apos; some &apos;eosinophil&apos;)</deletedAxiom>
<deletedAxiom>&apos;eosinophil mediated immunity&apos; SubClassOf &apos;mediated_by&apos; some &apos;eosinophil&apos;</deletedAxiom>
<newAxiom>&apos;eosinophil mediated immunity&apos; EquivalentTo &apos;immune system process&apos; and (&apos;has causal agent&apos; some &apos;eosinophil&apos;)</newAxiom>
<newAxiom>&apos;eosinophil mediated immunity&apos; SubClassOf &apos;has causal agent&apos; some &apos;eosinophil&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002446</classIRI>
<classLabel>neutrophil mediated immunity</classLabel>
<deletedAxiom>&apos;neutrophil mediated immunity&apos; SubClassOf &apos;mediated_by&apos; some &apos;neutrophil&apos;</deletedAxiom>
<deletedAxiom>&apos;neutrophil mediated immunity&apos; EquivalentTo &apos;immune system process&apos; and (&apos;mediated_by&apos; some &apos;neutrophil&apos;)</deletedAxiom>
<newAxiom>&apos;neutrophil mediated immunity&apos; EquivalentTo &apos;immune system process&apos; and (&apos;has causal agent&apos; some &apos;neutrophil&apos;)</newAxiom>
<newAxiom>&apos;neutrophil mediated immunity&apos; SubClassOf &apos;has causal agent&apos; some &apos;neutrophil&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002444</classIRI>
<classLabel>myeloid leukocyte mediated immunity</classLabel>
<deletedAxiom>&apos;myeloid leukocyte mediated immunity&apos; SubClassOf &apos;mediated_by&apos; some &apos;myeloid leukocyte&apos;</deletedAxiom>
<deletedAxiom>&apos;myeloid leukocyte mediated immunity&apos; EquivalentTo &apos;immune system process&apos; and (&apos;mediated_by&apos; some &apos;myeloid leukocyte&apos;)</deletedAxiom>
<newAxiom>&apos;myeloid leukocyte mediated immunity&apos; EquivalentTo &apos;immune system process&apos; and (&apos;has causal agent&apos; some &apos;myeloid leukocyte&apos;)</newAxiom>
<newAxiom>&apos;myeloid leukocyte mediated immunity&apos; SubClassOf &apos;has causal agent&apos; some &apos;myeloid leukocyte&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002443</classIRI>
<classLabel>leukocyte mediated immunity</classLabel>
<deletedAxiom>&apos;leukocyte mediated immunity&apos; EquivalentTo &apos;immune system process&apos; and (&apos;mediated_by&apos; some &apos;leukocyte&apos;)</deletedAxiom>
<deletedAxiom>&apos;leukocyte mediated immunity&apos; SubClassOf &apos;mediated_by&apos; some &apos;leukocyte&apos;</deletedAxiom>
<newAxiom>&apos;leukocyte mediated immunity&apos; SubClassOf &apos;has causal agent&apos; some &apos;leukocyte&apos;</newAxiom>
<newAxiom>&apos;leukocyte mediated immunity&apos; EquivalentTo &apos;immune system process&apos; and (&apos;has causal agent&apos; some &apos;leukocyte&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002424</classIRI>
<classLabel>T cell mediated immune response to tumor cell</classLabel>
<deletedAxiom>&apos;T cell mediated immune response to tumor cell&apos; EquivalentTo &apos;immune response to tumor cell&apos; and (&apos;mediated_by&apos; some &apos;T cell&apos;)</deletedAxiom>
<newAxiom>&apos;T cell mediated immune response to tumor cell&apos; EquivalentTo &apos;immune response to tumor cell&apos; and (&apos;has causal agent&apos; some &apos;T cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002423</classIRI>
<classLabel>natural killer cell mediated immune response to tumor cell</classLabel>
<deletedAxiom>&apos;natural killer cell mediated immune response to tumor cell&apos; EquivalentTo &apos;immune response to tumor cell&apos; and (&apos;mediated_by&apos; some &apos;natural killer cell&apos;)</deletedAxiom>
<newAxiom>&apos;natural killer cell mediated immune response to tumor cell&apos; EquivalentTo &apos;immune response to tumor cell&apos; and (&apos;has causal agent&apos; some &apos;natural killer cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002415</classIRI>
<classLabel>immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor</classLabel>
<deletedAxiom>&apos;immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor&apos; EquivalentTo &apos;immunoglobulin transcytosis in epithelial cells&apos; and (&apos;mediated_by&apos; some &apos;polymeric immunoglobulin receptor&apos;)</deletedAxiom>
<deletedAxiom>&apos;immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor&apos; SubClassOf &apos;mediated_by&apos; some &apos;polymeric immunoglobulin receptor&apos;</deletedAxiom>
<newAxiom>&apos;immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor&apos; EquivalentTo &apos;immunoglobulin transcytosis in epithelial cells&apos; and (&apos;has causal agent&apos; some &apos;polymeric immunoglobulin receptor&apos;)</newAxiom>
<newAxiom>&apos;immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor&apos; SubClassOf &apos;has causal agent&apos; some &apos;polymeric immunoglobulin receptor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002411</classIRI>
<classLabel>T cell tolerance induction to tumor cell</classLabel>
<deletedAxiom>&apos;T cell tolerance induction to tumor cell&apos; EquivalentTo &apos;tolerance induction to tumor cell&apos; and (&apos;mediated_by&apos; some &apos;T cell&apos;)</deletedAxiom>
<newAxiom>&apos;T cell tolerance induction to tumor cell&apos; EquivalentTo &apos;tolerance induction to tumor cell&apos; and (&apos;has causal agent&apos; some &apos;T cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002403</classIRI>
<classLabel>T cell tolerance induction in mucosal-associated lymphoid tissue</classLabel>
<deletedAxiom>&apos;T cell tolerance induction in mucosal-associated lymphoid tissue&apos; EquivalentTo &apos;tolerance induction in mucosal-associated lymphoid tissue&apos; and (&apos;mediated_by&apos; some &apos;T cell&apos;)</deletedAxiom>
<newAxiom>&apos;T cell tolerance induction in mucosal-associated lymphoid tissue&apos; EquivalentTo &apos;tolerance induction in mucosal-associated lymphoid tissue&apos; and (&apos;has causal agent&apos; some &apos;T cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002402</classIRI>
<classLabel>B cell tolerance induction in mucosal-associated lymphoid tissue</classLabel>
<deletedAxiom>&apos;B cell tolerance induction in mucosal-associated lymphoid tissue&apos; EquivalentTo &apos;tolerance induction in mucosal-associated lymphoid tissue&apos; and (&apos;mediated_by&apos; some &apos;B cell&apos;)</deletedAxiom>
<newAxiom>&apos;B cell tolerance induction in mucosal-associated lymphoid tissue&apos; EquivalentTo &apos;tolerance induction in mucosal-associated lymphoid tissue&apos; and (&apos;has causal agent&apos; some &apos;B cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002389</classIRI>
<classLabel>tolerance induction in Peyer&apos;s patch</classLabel>
<newAxiom>&apos;tolerance induction in Peyer&apos;s patch&apos; SubClassOf &apos;in taxon&apos; only &apos;Amniota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002388</classIRI>
<classLabel>immune response in Peyer&apos;s patch</classLabel>
<newAxiom>&apos;immune response in Peyer&apos;s patch&apos; SubClassOf &apos;in taxon&apos; only &apos;Amniota&apos;</newAxiom>
<newAxiom>&apos;immune response in Peyer&apos;s patch&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Amniota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002384</classIRI>
<classLabel>hepatic immune response</classLabel>
<newAxiom>&apos;hepatic immune response&apos; SubClassOf &apos;in taxon&apos; only &apos;Vertebrata vertebrates&apos;</newAxiom>
<newAxiom>&apos;hepatic immune response&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Vertebrata vertebrates&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002373</classIRI>
<classLabel>plasmacytoid dendritic cell cytokine production</classLabel>
<deletedAxiom>&apos;plasmacytoid dendritic cell cytokine production&apos; EquivalentTo &apos;cytokine production&apos; and (&apos;mediated_by&apos; some &apos;plasmacytoid dendritic cell&apos;)</deletedAxiom>
<deletedAxiom>&apos;plasmacytoid dendritic cell cytokine production&apos; SubClassOf &apos;mediated_by&apos; some &apos;plasmacytoid dendritic cell&apos;</deletedAxiom>
<newAxiom>&apos;plasmacytoid dendritic cell cytokine production&apos; EquivalentTo &apos;cytokine production&apos; and (&apos;has causal agent&apos; some &apos;plasmacytoid dendritic cell&apos;)</newAxiom>
<newAxiom>&apos;plasmacytoid dendritic cell cytokine production&apos; SubClassOf &apos;has causal agent&apos; some &apos;plasmacytoid dendritic cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002372</classIRI>
<classLabel>myeloid dendritic cell cytokine production</classLabel>
<deletedAxiom>&apos;myeloid dendritic cell cytokine production&apos; EquivalentTo &apos;cytokine production&apos; and (&apos;mediated_by&apos; some &apos;myeloid dendritic cell&apos;)</deletedAxiom>
<deletedAxiom>&apos;myeloid dendritic cell cytokine production&apos; SubClassOf &apos;mediated_by&apos; some &apos;myeloid dendritic cell&apos;</deletedAxiom>
<newAxiom>&apos;myeloid dendritic cell cytokine production&apos; SubClassOf &apos;has causal agent&apos; some &apos;myeloid dendritic cell&apos;</newAxiom>
<newAxiom>&apos;myeloid dendritic cell cytokine production&apos; EquivalentTo &apos;cytokine production&apos; and (&apos;has causal agent&apos; some &apos;myeloid dendritic cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002371</classIRI>
<classLabel>dendritic cell cytokine production</classLabel>
<deletedAxiom>&apos;dendritic cell cytokine production&apos; EquivalentTo &apos;cytokine production&apos; and (&apos;mediated_by&apos; some &apos;dendritic cell&apos;)</deletedAxiom>
<deletedAxiom>&apos;dendritic cell cytokine production&apos; SubClassOf &apos;mediated_by&apos; some &apos;dendritic cell&apos;</deletedAxiom>
<newAxiom>&apos;dendritic cell cytokine production&apos; SubClassOf &apos;has causal agent&apos; some &apos;dendritic cell&apos;</newAxiom>
<newAxiom>&apos;dendritic cell cytokine production&apos; EquivalentTo &apos;cytokine production&apos; and (&apos;has causal agent&apos; some &apos;dendritic cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002370</classIRI>
<classLabel>natural killer cell cytokine production</classLabel>
<deletedAxiom>&apos;natural killer cell cytokine production&apos; EquivalentTo &apos;cytokine production&apos; and (&apos;mediated_by&apos; some &apos;natural killer cell&apos;)</deletedAxiom>
<newAxiom>&apos;natural killer cell cytokine production&apos; EquivalentTo &apos;cytokine production&apos; and (&apos;has causal agent&apos; some &apos;natural killer cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002369</classIRI>
<classLabel>T cell cytokine production</classLabel>
<deletedAxiom>&apos;T cell cytokine production&apos; EquivalentTo &apos;cytokine production&apos; and (&apos;mediated_by&apos; some &apos;T cell&apos;)</deletedAxiom>
<newAxiom>&apos;T cell cytokine production&apos; EquivalentTo &apos;cytokine production&apos; and (&apos;has causal agent&apos; some &apos;T cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002368</classIRI>
<classLabel>B cell cytokine production</classLabel>
<deletedAxiom>&apos;B cell cytokine production&apos; EquivalentTo &apos;cytokine production&apos; and (&apos;mediated_by&apos; some &apos;B cell&apos;)</deletedAxiom>
<newAxiom>&apos;B cell cytokine production&apos; EquivalentTo &apos;cytokine production&apos; and (&apos;has causal agent&apos; some &apos;B cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110094</classIRI>
<classLabel>polyphosphate-mediated signaling</classLabel>
<deletedAxiom>&apos;polyphosphate-mediated signaling&apos; SubClassOf &apos;mediated_by&apos; some &apos;polyphosphate&apos;</deletedAxiom>
<deletedAxiom>&apos;polyphosphate-mediated signaling&apos; EquivalentTo &apos;cell-cell signaling&apos; and (&apos;mediated_by&apos; some &apos;polyphosphate&apos;)</deletedAxiom>
<newAxiom>&apos;polyphosphate-mediated signaling&apos; SubClassOf &apos;has causal agent&apos; some &apos;polyphosphate&apos;</newAxiom>
<newAxiom>&apos;polyphosphate-mediated signaling&apos; EquivalentTo &apos;cell-cell signaling&apos; and (&apos;has causal agent&apos; some &apos;polyphosphate&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099183</classIRI>
<classLabel>trans-synaptic signaling by BDNF, modulating synaptic transmission</classLabel>
<deletedAxiom>&apos;trans-synaptic signaling by BDNF, modulating synaptic transmission&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;brain-derived neurotrophic factor&apos;) and (&apos;regulates&apos; some &apos;chemical synaptic transmission&apos;)</deletedAxiom>
<newAxiom>&apos;trans-synaptic signaling by BDNF, modulating synaptic transmission&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;regulates&apos; some &apos;chemical synaptic transmission&apos;) and (&apos;has causal agent&apos; some &apos;brain-derived neurotrophic factor&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099191</classIRI>
<classLabel>trans-synaptic signaling by BDNF</classLabel>
<deletedAxiom>&apos;trans-synaptic signaling by BDNF&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;brain-derived neurotrophic factor&apos;)</deletedAxiom>
<deletedAxiom>&apos;trans-synaptic signaling by BDNF&apos; SubClassOf &apos;mediated_by&apos; some &apos;brain-derived neurotrophic factor&apos;</deletedAxiom>
<newAxiom>&apos;trans-synaptic signaling by BDNF&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;has causal agent&apos; some &apos;brain-derived neurotrophic factor&apos;)</newAxiom>
<newAxiom>&apos;trans-synaptic signaling by BDNF&apos; SubClassOf &apos;has causal agent&apos; some &apos;brain-derived neurotrophic factor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110077</classIRI>
<classLabel>vesicle-mediated intercellular transport</classLabel>
<deletedAxiom>&apos;vesicle-mediated intercellular transport&apos; EquivalentTo &apos;intercellular transport&apos; and (&apos;mediated_by&apos; some &apos;extracellular vesicle&apos;)</deletedAxiom>
<deletedAxiom>&apos;vesicle-mediated intercellular transport&apos; SubClassOf &apos;mediated_by&apos; some &apos;extracellular vesicle&apos;</deletedAxiom>
<newAxiom>&apos;vesicle-mediated intercellular transport&apos; SubClassOf &apos;has causal agent&apos; some &apos;extracellular vesicle&apos;</newAxiom>
<newAxiom>&apos;vesicle-mediated intercellular transport&apos; EquivalentTo &apos;intercellular transport&apos; and (&apos;has causal agent&apos; some &apos;extracellular vesicle&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099157</classIRI>
<classLabel>trans-synaptic signalling via exosome</classLabel>
<deletedAxiom>&apos;trans-synaptic signalling via exosome&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;extracellular exosome&apos;)</deletedAxiom>
<newAxiom>&apos;trans-synaptic signalling via exosome&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;has causal agent&apos; some &apos;extracellular exosome&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099156</classIRI>
<classLabel>cell-cell signaling via exosome</classLabel>
<deletedAxiom>&apos;cell-cell signaling via exosome&apos; EquivalentTo &apos;cell-cell signaling&apos; and (&apos;mediated_by&apos; some &apos;extracellular exosome&apos;)</deletedAxiom>
<deletedAxiom>&apos;cell-cell signaling via exosome&apos; SubClassOf &apos;mediated_by&apos; some &apos;extracellular exosome&apos;</deletedAxiom>
<newAxiom>&apos;cell-cell signaling via exosome&apos; EquivalentTo &apos;cell-cell signaling&apos; and (&apos;has causal agent&apos; some &apos;extracellular exosome&apos;)</newAxiom>
<newAxiom>&apos;cell-cell signaling via exosome&apos; SubClassOf &apos;has causal agent&apos; some &apos;extracellular exosome&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099163</classIRI>
<classLabel>synaptic signaling by nitric oxide</classLabel>
<deletedAxiom>&apos;synaptic signaling by nitric oxide&apos; SubClassOf &apos;mediated_by&apos; some &apos;nitric oxide&apos;</deletedAxiom>
<deletedAxiom>&apos;synaptic signaling by nitric oxide&apos; EquivalentTo &apos;synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;nitric oxide&apos;)</deletedAxiom>
<newAxiom>&apos;synaptic signaling by nitric oxide&apos; EquivalentTo &apos;synaptic signaling&apos; and (&apos;has causal agent&apos; some &apos;nitric oxide&apos;)</newAxiom>
<newAxiom>&apos;synaptic signaling by nitric oxide&apos; SubClassOf &apos;has causal agent&apos; some &apos;nitric oxide&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002181</classIRI>
<classLabel>cytoplasmic translation</classLabel>
<deletedAxiom>&apos;cytoplasmic translation&apos; EquivalentTo &apos;translation&apos; and (&apos;mediated_by&apos; some &apos;cytosolic ribosome&apos;)</deletedAxiom>
<deletedAxiom>&apos;cytoplasmic translation&apos; SubClassOf &apos;mediated_by&apos; some &apos;cytosolic ribosome&apos;</deletedAxiom>
<newAxiom>&apos;cytoplasmic translation&apos; SubClassOf &apos;has causal agent&apos; some &apos;cytosolic ribosome&apos;</newAxiom>
<newAxiom>&apos;cytoplasmic translation&apos; EquivalentTo &apos;translation&apos; and (&apos;has causal agent&apos; some &apos;cytosolic ribosome&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002228</classIRI>
<classLabel>natural killer cell mediated immunity</classLabel>
<deletedAxiom>&apos;natural killer cell mediated immunity&apos; EquivalentTo &apos;immune system process&apos; and (&apos;mediated_by&apos; some &apos;natural killer cell&apos;)</deletedAxiom>
<deletedAxiom>&apos;natural killer cell mediated immunity&apos; SubClassOf &apos;mediated_by&apos; some &apos;natural killer cell&apos;</deletedAxiom>
<newAxiom>&apos;natural killer cell mediated immunity&apos; EquivalentTo &apos;immune system process&apos; and (&apos;has causal agent&apos; some &apos;natural killer cell&apos;)</newAxiom>
<newAxiom>&apos;natural killer cell mediated immunity&apos; SubClassOf &apos;has causal agent&apos; some &apos;natural killer cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002227</classIRI>
<classLabel>innate immune response in mucosa</classLabel>
<newAxiom>&apos;innate immune response in mucosa&apos; SubClassOf &apos;in taxon&apos; only &apos;Chordata&apos;</newAxiom>
<newAxiom>&apos;innate immune response in mucosa&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Chordata&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075128</classIRI>
<classLabel>positive regulation by symbiont of host signal transduction mediated by G-protein gamma subunit</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host signal transduction mediated by G-protein gamma subunit&apos; SubClassOf &apos;modulation by symbiont of host signal transduction mediated by G-protein gamma subunit&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host signal transduction mediated by G-protein gamma subunit&apos; SubClassOf &apos;positive regulation by symbiont of host G protein-coupled receptor signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075127</classIRI>
<classLabel>modulation by symbiont of host signal transduction mediated by G-protein gamma subunit</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host signal transduction mediated by G-protein gamma subunit&apos; SubClassOf &apos;modulation by symbiont of host G protein-coupled receptor signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075126</classIRI>
<classLabel>negative regulation by symbiont of host signal transduction mediated by G-protein beta subunit</classLabel>
<deletedAxiom>&apos;negative regulation by symbiont of host signal transduction mediated by G-protein beta subunit&apos; SubClassOf &apos;negative regulation by symbiont of host G protein-coupled receptor signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation by symbiont of host signal transduction mediated by G-protein beta subunit&apos; SubClassOf &apos;modulation by symbiont of host signal transduction mediated by G-protein beta subunit&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075125</classIRI>
<classLabel>positive regulation by symbiont of host signal transduction mediated by G-protein beta subunit</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host signal transduction mediated by G-protein beta subunit&apos; SubClassOf &apos;modulation by symbiont of host signal transduction mediated by G-protein beta subunit&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host signal transduction mediated by G-protein beta subunit&apos; SubClassOf &apos;positive regulation by symbiont of host G protein-coupled receptor signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075129</classIRI>
<classLabel>negative regulation by symbiont of host signal transduction mediated by G-protein gamma subunit</classLabel>
<deletedAxiom>&apos;negative regulation by symbiont of host signal transduction mediated by G-protein gamma subunit&apos; SubClassOf &apos;modulation by symbiont of host signal transduction mediated by G-protein gamma subunit&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation by symbiont of host signal transduction mediated by G-protein gamma subunit&apos; SubClassOf &apos;negative regulation by symbiont of host G protein-coupled receptor signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903392</classIRI>
<classLabel>negative regulation of adherens junction organization</classLabel>
<deletedAxiom>&apos;negative regulation of adherens junction organization&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;adherens junction organization&apos;)</deletedAxiom>
<newAxiom>&apos;negative regulation of adherens junction organization&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;adherens junction organization&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903391</classIRI>
<classLabel>regulation of adherens junction organization</classLabel>
<deletedAxiom>&apos;regulation of adherens junction organization&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;adherens junction organization&apos;)</deletedAxiom>
<newAxiom>&apos;regulation of adherens junction organization&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;adherens junction organization&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903393</classIRI>
<classLabel>positive regulation of adherens junction organization</classLabel>
<deletedAxiom>&apos;positive regulation of adherens junction organization&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;adherens junction organization&apos;)</deletedAxiom>
<newAxiom>&apos;positive regulation of adherens junction organization&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;adherens junction organization&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099111</classIRI>
<classLabel>microtubule-based transport</classLabel>
<deletedAxiom>&apos;microtubule-based transport&apos; EquivalentTo &apos;transport&apos; and (&apos;mediated_by&apos; some &apos;microtubule&apos;)</deletedAxiom>
<newAxiom>&apos;microtubule-based transport&apos; EquivalentTo &apos;transport&apos; and (&apos;has causal agent&apos; some &apos;microtubule&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099110</classIRI>
<classLabel>microtubule polymerization based protein transport to cell tip cortex</classLabel>
<deletedAxiom>&apos;microtubule polymerization based protein transport to cell tip cortex&apos; EquivalentTo &apos;intracellular transport&apos; and (&apos;has_part&apos; some &apos;microtubule polymerization&apos;) and (&apos;mediated_by&apos; some &apos;microtubule&apos;) and (&apos;transports or maintains localization of&apos; some &apos;protein&apos;) and (&apos;has target end location&apos; some &apos;cell cortex of cell tip&apos;)</deletedAxiom>
<newAxiom>&apos;microtubule polymerization based protein transport to cell tip cortex&apos; EquivalentTo &apos;intracellular transport&apos; and (&apos;has_part&apos; some &apos;microtubule polymerization&apos;) and (&apos;transports or maintains localization of&apos; some &apos;protein&apos;) and (&apos;has target end location&apos; some &apos;cell cortex of cell tip&apos;) and (&apos;has causal agent&apos; some &apos;microtubule&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075124</classIRI>
<classLabel>modulation by symbiont of host signal transduction mediated by G-protein beta subunit</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host signal transduction mediated by G-protein beta subunit&apos; SubClassOf &apos;modulation by symbiont of host G protein-coupled receptor signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075123</classIRI>
<classLabel>negative regulation by symbiont of host signal transduction mediated by G-protein alpha subunit</classLabel>
<deletedAxiom>&apos;negative regulation by symbiont of host signal transduction mediated by G-protein alpha subunit&apos; SubClassOf &apos;negative regulation by symbiont of host G protein-coupled receptor signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation by symbiont of host signal transduction mediated by G-protein alpha subunit&apos; SubClassOf &apos;modulation by symbiont of host signal transduction mediated by G-protein alpha subunit&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099112</classIRI>
<classLabel>microtubule polymerization based protein transport</classLabel>
<deletedAxiom>&apos;microtubule polymerization based protein transport&apos; EquivalentTo &apos;intracellular transport&apos; and (&apos;has_part&apos; some &apos;microtubule polymerization&apos;) and (&apos;mediated_by&apos; some &apos;microtubule&apos;) and (&apos;transports or maintains localization of&apos; some &apos;protein&apos;)</deletedAxiom>
<newAxiom>&apos;microtubule polymerization based protein transport&apos; EquivalentTo &apos;intracellular transport&apos; and (&apos;has_part&apos; some &apos;microtubule polymerization&apos;) and (&apos;transports or maintains localization of&apos; some &apos;protein&apos;) and (&apos;has causal agent&apos; some &apos;microtubule&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075122</classIRI>
<classLabel>positive regulation by symbiont of host signal transduction mediated by G-protein alpha subunit</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host signal transduction mediated by G-protein alpha subunit&apos; SubClassOf &apos;positive regulation by symbiont of host G protein-coupled receptor signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host signal transduction mediated by G-protein alpha subunit&apos; SubClassOf &apos;modulation by symbiont of host signal transduction mediated by G-protein alpha subunit&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075121</classIRI>
<classLabel>modulation by symbiont of host signal transduction mediated by G-protein alpha subunit</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host signal transduction mediated by G-protein alpha subunit&apos; SubClassOf &apos;modulation by symbiont of host G protein-coupled receptor signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099118</classIRI>
<classLabel>microtubule-based protein transport</classLabel>
<deletedAxiom>&apos;microtubule-based protein transport&apos; EquivalentTo &apos;transport&apos; and (&apos;mediated_by&apos; some &apos;microtubule&apos;) and (&apos;transports or maintains localization of&apos; some &apos;protein&apos;)</deletedAxiom>
<newAxiom>&apos;microtubule-based protein transport&apos; EquivalentTo &apos;transport&apos; and (&apos;transports or maintains localization of&apos; some &apos;protein&apos;) and (&apos;has causal agent&apos; some &apos;microtubule&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099074</classIRI>
<classLabel>mitochondrion to lysosome transport</classLabel>
<deletedAxiom>&apos;mitochondrion to lysosome transport&apos; EquivalentTo &apos;transport&apos; and (&apos;mediated_by&apos; some &apos;mitochondrion-derived vesicle&apos;) and (&apos;has target start location&apos; some &apos;mitochondrion&apos;) and (&apos;has target end location&apos; some &apos;lysosome&apos;)</deletedAxiom>
<newAxiom>&apos;mitochondrion to lysosome transport&apos; EquivalentTo &apos;transport&apos; and (&apos;has target start location&apos; some &apos;mitochondrion&apos;) and (&apos;has target end location&apos; some &apos;lysosome&apos;) and (&apos;has causal agent&apos; some &apos;mitochondrion-derived vesicle&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099076</classIRI>
<classLabel>mitochondrion to peroxisome transport</classLabel>
<deletedAxiom>&apos;mitochondrion to peroxisome transport&apos; EquivalentTo &apos;transport&apos; and (&apos;mediated_by&apos; some &apos;mitochondrion-derived vesicle&apos;) and (&apos;has target start location&apos; some &apos;mitochondrion&apos;) and (&apos;has target end location&apos; some &apos;peroxisome&apos;)</deletedAxiom>
<newAxiom>&apos;mitochondrion to peroxisome transport&apos; EquivalentTo &apos;transport&apos; and (&apos;has target start location&apos; some &apos;mitochondrion&apos;) and (&apos;has target end location&apos; some &apos;peroxisome&apos;) and (&apos;has causal agent&apos; some &apos;mitochondrion-derived vesicle&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099075</classIRI>
<classLabel>mitochondrion-derived vesicle mediated transport</classLabel>
<deletedAxiom>&apos;mitochondrion-derived vesicle mediated transport&apos; SubClassOf &apos;mediated_by&apos; some &apos;mitochondrion-derived vesicle&apos;</deletedAxiom>
<deletedAxiom>&apos;mitochondrion-derived vesicle mediated transport&apos; EquivalentTo &apos;transport&apos; and (&apos;mediated_by&apos; some &apos;mitochondrion-derived vesicle&apos;) and (&apos;has target start location&apos; some &apos;mitochondrion&apos;)</deletedAxiom>
<newAxiom>&apos;mitochondrion-derived vesicle mediated transport&apos; EquivalentTo &apos;transport&apos; and (&apos;has target start location&apos; some &apos;mitochondrion&apos;) and (&apos;has causal agent&apos; some &apos;mitochondrion-derived vesicle&apos;)</newAxiom>
<newAxiom>&apos;mitochondrion-derived vesicle mediated transport&apos; SubClassOf &apos;has causal agent&apos; some &apos;mitochondrion-derived vesicle&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099083</classIRI>
<classLabel>retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission</classLabel>
<deletedAxiom>&apos;retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;peptide&apos;) and (&apos;regulates&apos; some &apos;chemical synaptic transmission&apos;) and (&apos;has start location&apos; some &apos;postsynapse&apos;) and (&apos;has end location&apos; some &apos;presynapse&apos;)</deletedAxiom>
<newAxiom>&apos;retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;regulates&apos; some &apos;chemical synaptic transmission&apos;) and (&apos;has start location&apos; some &apos;postsynapse&apos;) and (&apos;has end location&apos; some &apos;presynapse&apos;) and (&apos;has causal agent&apos; some &apos;peptide&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099082</classIRI>
<classLabel>retrograde trans-synaptic signaling by neuropeptide</classLabel>
<deletedAxiom>&apos;retrograde trans-synaptic signaling by neuropeptide&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;mediated_by&apos; some &apos;peptide&apos;) and (&apos;has start location&apos; some &apos;postsynapse&apos;) and (&apos;has end location&apos; some &apos;presynapse&apos;)</deletedAxiom>
<newAxiom>&apos;retrograde trans-synaptic signaling by neuropeptide&apos; EquivalentTo &apos;trans-synaptic signaling&apos; and (&apos;has start location&apos; some &apos;postsynapse&apos;) and (&apos;has end location&apos; some &apos;presynapse&apos;) and (&apos;has causal agent&apos; some &apos;peptide&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075061</classIRI>
<classLabel>formation of symbiont invasive hypha in host</classLabel>
<newAxiom>&apos;formation of symbiont invasive hypha in host&apos; SubClassOf &apos;hyphal growth&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075064</classIRI>
<classLabel>negative regulation of symbiont invasive hypha formation in host</classLabel>
<newAxiom>&apos;negative regulation of symbiont invasive hypha formation in host&apos; SubClassOf &apos;negative regulation of filamentous growth&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075063</classIRI>
<classLabel>positive regulation of symbiont invasive hypha formation in host</classLabel>
<newAxiom>&apos;positive regulation of symbiont invasive hypha formation in host&apos; SubClassOf &apos;positive regulation of filamentous growth&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075062</classIRI>
<classLabel>regulation of symbiont invasive hypha formation in host</classLabel>
<newAxiom>&apos;regulation of symbiont invasive hypha formation in host&apos; SubClassOf &apos;regulation of filamentous growth&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090634</classIRI>
<classLabel>microglial cell mediated cytotoxicity</classLabel>
<deletedAxiom>&apos;microglial cell mediated cytotoxicity&apos; SubClassOf &apos;mediated_by&apos; some &apos;microglial cell&apos;</deletedAxiom>
<deletedAxiom>&apos;microglial cell mediated cytotoxicity&apos; EquivalentTo &apos;cell killing&apos; and (&apos;mediated_by&apos; some &apos;microglial cell&apos;)</deletedAxiom>
<newAxiom>&apos;microglial cell mediated cytotoxicity&apos; EquivalentTo &apos;cell killing&apos; and (&apos;has causal agent&apos; some &apos;microglial cell&apos;)</newAxiom>
<newAxiom>&apos;microglial cell mediated cytotoxicity&apos; SubClassOf &apos;has causal agent&apos; some &apos;microglial cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090615</classIRI>
<classLabel>mitochondrial mRNA processing</classLabel>
<newAxiom>&apos;mitochondrial mRNA processing&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090616</classIRI>
<classLabel>mitochondrial mRNA 3&apos;-end processing</classLabel>
<newAxiom>&apos;mitochondrial mRNA 3&apos;-end processing&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099003</classIRI>
<classLabel>vesicle-mediated transport in synapse</classLabel>
<newAxiom>&apos;vesicle-mediated transport in synapse&apos; SubClassOf &apos;in taxon&apos; only &apos;Metazoa&apos;</newAxiom>
<newAxiom>&apos;vesicle-mediated transport in synapse&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Metazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090646</classIRI>
<classLabel>mitochondrial tRNA processing</classLabel>
<newAxiom>&apos;mitochondrial tRNA processing&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090222</classIRI>
<classLabel>centrosome-templated microtubule nucleation</classLabel>
<deletedAxiom>&apos;centrosome-templated microtubule nucleation&apos; EquivalentTo &apos;microtubule nucleation&apos; and (&apos;mediated_by&apos; some &apos;centrosome&apos;)</deletedAxiom>
<deletedAxiom>&apos;centrosome-templated microtubule nucleation&apos; SubClassOf &apos;mediated_by&apos; some &apos;centrosome&apos;</deletedAxiom>
<newAxiom>&apos;centrosome-templated microtubule nucleation&apos; SubClassOf &apos;has causal agent&apos; some &apos;centrosome&apos;</newAxiom>
<newAxiom>&apos;centrosome-templated microtubule nucleation&apos; EquivalentTo &apos;microtubule nucleation&apos; and (&apos;has causal agent&apos; some &apos;centrosome&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031929</classIRI>
<classLabel>TOR signaling</classLabel>
<deletedAxiom>&apos;TOR signaling&apos; EquivalentTo &apos;intracellular signal transduction&apos; and (&apos;mediated_by&apos; some &apos;TOR complex&apos;)</deletedAxiom>
<deletedAxiom>&apos;TOR signaling&apos; SubClassOf &apos;mediated_by&apos; some &apos;TOR complex&apos;</deletedAxiom>
<newAxiom>&apos;TOR signaling&apos; SubClassOf &apos;has causal agent&apos; some &apos;TOR complex&apos;</newAxiom>
<newAxiom>&apos;TOR signaling&apos; EquivalentTo &apos;intracellular signal transduction&apos; and (&apos;has causal agent&apos; some &apos;TOR complex&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006985</classIRI>
<classLabel>positive regulation of NF-kappaB transcription factor activity by ER overload response</classLabel>
<deletedAxiom>&apos;positive regulation of NF-kappaB transcription factor activity by ER overload response&apos; EquivalentTo &apos;ER overload response&apos; and (&apos;results_in&apos; some &apos;positive regulation of NF-kappaB transcription factor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of NF-kappaB transcription factor activity by ER overload response&apos; SubClassOf &apos;ER overload response&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of NF-kappaB transcription factor activity by ER overload response&apos; SubClassOf &apos;results_in&apos; some &apos;positive regulation of NF-kappaB transcription factor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of NF-kappaB transcription factor activity by ER overload response&apos; SubClassOf &apos;positive regulation of NF-kappaB transcription factor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006897</classIRI>
<classLabel>endocytosis</classLabel>
<deletedAxiom>&apos;endocytosis&apos; SubClassOf &apos;mediated_by&apos; some &apos;endocytic vesicle&apos;</deletedAxiom>
<deletedAxiom>&apos;endocytosis&apos; EquivalentTo &apos;vesicle-mediated transport&apos; and (&apos;mediated_by&apos; some &apos;endocytic vesicle&apos;) and (&apos;has target start location&apos; some &apos;extracellular region&apos;) and (&apos;has target end location&apos; some &apos;cytoplasmic vesicle&apos;)</deletedAxiom>
<newAxiom>&apos;endocytosis&apos; SubClassOf &apos;has causal agent&apos; some &apos;endocytic vesicle&apos;</newAxiom>
<newAxiom>&apos;endocytosis&apos; EquivalentTo &apos;vesicle-mediated transport&apos; and (&apos;has target start location&apos; some &apos;extracellular region&apos;) and (&apos;has target end location&apos; some &apos;cytoplasmic vesicle&apos;) and (&apos;has causal agent&apos; some &apos;endocytic vesicle&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090119</classIRI>
<classLabel>vesicle-mediated cholesterol transport</classLabel>
<deletedAxiom>&apos;vesicle-mediated cholesterol transport&apos; EquivalentTo &apos;cholesterol transport&apos; and (&apos;occurs in&apos; some &apos;cytosol&apos;) and (&apos;mediated_by&apos; some &apos;vesicle&apos;)</deletedAxiom>
<newAxiom>&apos;vesicle-mediated cholesterol transport&apos; EquivalentTo &apos;cholesterol transport&apos; and (&apos;occurs in&apos; some &apos;cytosol&apos;) and (&apos;has causal agent&apos; some &apos;vesicle&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090109</classIRI>
<classLabel>regulation of cell-substrate junction assembly</classLabel>
<deletedAxiom>&apos;regulation of cell-substrate junction assembly&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;cell-substrate junction assembly&apos;)</deletedAxiom>
<newAxiom>&apos;regulation of cell-substrate junction assembly&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0150116</newAxiom>
<newAxiom>&apos;regulation of cell-substrate junction assembly&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;cell-substrate junction assembly&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090144</classIRI>
<classLabel>mitochondrial nucleoid organization</classLabel>
<newAxiom>&apos;mitochondrial nucleoid organization&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;mitochondrial nucleoid organization&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090139</classIRI>
<classLabel>mitochondrial DNA packaging</classLabel>
<newAxiom>&apos;mitochondrial DNA packaging&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;mitochondrial DNA packaging&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016192</classIRI>
<classLabel>vesicle-mediated transport</classLabel>
<deletedAxiom>&apos;vesicle-mediated transport&apos; EquivalentTo &apos;transport&apos; and (&apos;mediated_by&apos; some &apos;vesicle&apos;)</deletedAxiom>
<deletedAxiom>&apos;vesicle-mediated transport&apos; SubClassOf &apos;mediated_by&apos; some &apos;vesicle&apos;</deletedAxiom>
<newAxiom>&apos;vesicle-mediated transport&apos; EquivalentTo &apos;transport&apos; and (&apos;has causal agent&apos; some &apos;vesicle&apos;)</newAxiom>
<newAxiom>&apos;vesicle-mediated transport&apos; SubClassOf &apos;has causal agent&apos; some &apos;vesicle&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016197</classIRI>
<classLabel>endosomal transport</classLabel>
<deletedAxiom>&apos;endosomal transport&apos; SubClassOf &apos;mediated_by&apos; some &apos;endosome&apos;</deletedAxiom>
<deletedAxiom>&apos;endosomal transport&apos; EquivalentTo &apos;transport&apos; and (&apos;occurs in&apos; some &apos;intracellular&apos;) and (&apos;mediated_by&apos; some &apos;endosome&apos;)</deletedAxiom>
<newAxiom>&apos;endosomal transport&apos; EquivalentTo &apos;transport&apos; and (&apos;occurs in&apos; some &apos;intracellular&apos;) and (&apos;has causal agent&apos; some &apos;endosome&apos;)</newAxiom>
<newAxiom>&apos;endosomal transport&apos; SubClassOf &apos;has causal agent&apos; some &apos;endosome&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016047</classIRI>
<classLabel>detection of parasitic fungus</classLabel>
<deletedAxiom>&apos;detection of parasitic fungus&apos; SubClassOf &apos;detection of symbiotic fungus&apos;</deletedAxiom>
<deletedAxiom>&apos;detection of parasitic fungus&apos; SubClassOf &apos;response to parasitic fungus&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016056</classIRI>
<classLabel>rhodopsin mediated signaling pathway</classLabel>
<deletedAxiom>&apos;rhodopsin mediated signaling pathway&apos; SubClassOf &apos;mediated_by&apos; some &apos;rhodopsin&apos;</deletedAxiom>
<deletedAxiom>&apos;rhodopsin mediated signaling pathway&apos; EquivalentTo &apos;phototransduction&apos; and (&apos;mediated_by&apos; some &apos;rhodopsin&apos;)</deletedAxiom>
<newAxiom>&apos;rhodopsin mediated signaling pathway&apos; EquivalentTo &apos;phototransduction&apos; and (&apos;has causal agent&apos; some &apos;rhodopsin&apos;)</newAxiom>
<newAxiom>&apos;rhodopsin mediated signaling pathway&apos; SubClassOf &apos;has causal agent&apos; some &apos;rhodopsin&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006539</classIRI>
<classLabel>glutamate catabolic process via 2-oxoglutarate</classLabel>
<deletedAxiom>&apos;glutamate catabolic process via 2-oxoglutarate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some &apos;2-oxoglutarate(2-)&apos;) and (&apos;has primary input&apos; some &apos;glutamate(2-)&apos;)</deletedAxiom>
<deletedAxiom>&apos;glutamate catabolic process via 2-oxoglutarate&apos; SubClassOf &apos;has intermediate&apos; some &apos;2-oxoglutarate(2-)&apos;</deletedAxiom>
<newAxiom>&apos;glutamate catabolic process via 2-oxoglutarate&apos; EquivalentTo &apos;catabolic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;2-oxoglutarate(2-)&apos;) and (&apos;has primary input&apos; some &apos;glutamate(2-)&apos;)</newAxiom>
<newAxiom>&apos;glutamate catabolic process via 2-oxoglutarate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;2-oxoglutarate(2-)&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006575</classIRI>
<classLabel>cellular modified amino acid metabolic process</classLabel>
<deletedAxiom>&apos;cellular modified amino acid metabolic process&apos; SubClassOf &apos;has_participant&apos; some &apos;amino acid derivative&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular modified amino acid metabolic process&apos; EquivalentTo &apos;cellular metabolic process&apos; and (&apos;has_participant&apos; some &apos;amino acid derivative&apos;)</deletedAxiom>
<newAxiom>&apos;cellular modified amino acid metabolic process&apos; EquivalentTo &apos;cellular metabolic process&apos; and (&apos;has primary input or output&apos; some &apos;amino acid derivative&apos;)</newAxiom>
<newAxiom>&apos;cellular modified amino acid metabolic process&apos; SubClassOf &apos;has primary input or output&apos; some &apos;amino acid derivative&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070901</classIRI>
<classLabel>mitochondrial tRNA methylation</classLabel>
<newAxiom>&apos;mitochondrial tRNA methylation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070900</classIRI>
<classLabel>mitochondrial tRNA modification</classLabel>
<newAxiom>&apos;mitochondrial tRNA modification&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070903</classIRI>
<classLabel>mitochondrial tRNA thio-modification</classLabel>
<newAxiom>&apos;mitochondrial tRNA thio-modification&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070902</classIRI>
<classLabel>mitochondrial tRNA pseudouridine synthesis</classLabel>
<newAxiom>&apos;mitochondrial tRNA pseudouridine synthesis&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006390</classIRI>
<classLabel>mitochondrial transcription</classLabel>
<newAxiom>&apos;mitochondrial transcription&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006393</classIRI>
<classLabel>termination of mitochondrial transcription</classLabel>
<newAxiom>&apos;termination of mitochondrial transcription&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070942</classIRI>
<classLabel>neutrophil mediated cytotoxicity</classLabel>
<deletedAxiom>&apos;neutrophil mediated cytotoxicity&apos; EquivalentTo &apos;cell killing&apos; and (&apos;mediated_by&apos; some &apos;neutrophil&apos;)</deletedAxiom>
<newAxiom>&apos;neutrophil mediated cytotoxicity&apos; EquivalentTo &apos;cell killing&apos; and (&apos;has causal agent&apos; some &apos;neutrophil&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070899</classIRI>
<classLabel>mitochondrial tRNA wobble uridine modification</classLabel>
<newAxiom>&apos;mitochondrial tRNA wobble uridine modification&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006264</classIRI>
<classLabel>mitochondrial DNA replication</classLabel>
<newAxiom>&apos;mitochondrial DNA replication&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;mitochondrial DNA replication&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070833</classIRI>
<classLabel>phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine</classLabel>
<deletedAxiom>&apos;phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;CDP-N-methylethanolamine&apos;) and (&apos;has primary output&apos; some &apos;phosphatidylcholine&apos;) and (&apos;has primary input&apos; some &apos;O-phosphonatoethanaminium(1-)&apos;)</deletedAxiom>
<deletedAxiom>&apos;phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine&apos; SubClassOf &apos;has intermediate&apos; some &apos;CDP-N-methylethanolamine&apos;</deletedAxiom>
<newAxiom>&apos;phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;CDP-N-methylethanolamine&apos;) and (&apos;has primary output&apos; some &apos;phosphatidylcholine&apos;) and (&apos;has primary input&apos; some &apos;O-phosphonatoethanaminium(1-)&apos;)</newAxiom>
<newAxiom>&apos;phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;CDP-N-methylethanolamine&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070832</classIRI>
<classLabel>phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline</classLabel>
<deletedAxiom>&apos;phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline&apos; SubClassOf &apos;has intermediate&apos; some &apos;CDP-choline&apos;</deletedAxiom>
<deletedAxiom>&apos;phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline&apos; SubClassOf &apos;has intermediate&apos; some &apos;N,N-dimethylethanolamine phosphate&apos;</deletedAxiom>
<deletedAxiom>&apos;phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;CDP-choline&apos;) and (&apos;has intermediate&apos; some &apos;N,N-dimethylethanolamine phosphate&apos;) and (&apos;has input&apos; some &apos;O-phosphonatoethanaminium(1-)&apos;) and (&apos;has primary output&apos; some &apos;phosphatidylcholine&apos;)</deletedAxiom>
<newAxiom>&apos;phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some &apos;O-phosphonatoethanaminium(1-)&apos;) and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;CDP-choline&apos;) and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;N,N-dimethylethanolamine phosphate&apos;) and (&apos;has primary output&apos; some &apos;phosphatidylcholine&apos;)</newAxiom>
<newAxiom>&apos;phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;N,N-dimethylethanolamine phosphate&apos;</newAxiom>
<newAxiom>&apos;phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;CDP-choline&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070834</classIRI>
<classLabel>phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine</classLabel>
<deletedAxiom>&apos;phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine&apos; SubClassOf &apos;has intermediate&apos; some &apos;N,N-dimethylethanolamine phosphate&apos;</deletedAxiom>
<deletedAxiom>&apos;phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;N,N-dimethylethanolamine phosphate&apos;) and (&apos;has intermediate&apos; some &apos;CDP-N,N-dimethylethanolamine&apos;) and (&apos;has input&apos; some &apos;O-phosphonatoethanaminium(1-)&apos;) and (&apos;has primary output&apos; some &apos;phosphatidylcholine&apos;)</deletedAxiom>
<deletedAxiom>&apos;phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine&apos; SubClassOf &apos;has intermediate&apos; some &apos;CDP-N,N-dimethylethanolamine&apos;</deletedAxiom>
<newAxiom>&apos;phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;N,N-dimethylethanolamine phosphate&apos;</newAxiom>
<newAxiom>&apos;phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;CDP-N,N-dimethylethanolamine&apos;</newAxiom>
<newAxiom>&apos;phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has input&apos; some &apos;O-phosphonatoethanaminium(1-)&apos;) and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;N,N-dimethylethanolamine phosphate&apos;) and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;CDP-N,N-dimethylethanolamine&apos;) and (&apos;has primary output&apos; some &apos;phosphatidylcholine&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045785</classIRI>
<classLabel>positive regulation of cell adhesion</classLabel>
<deletedAxiom>&apos;positive regulation of cell adhesion&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;cell adhesion&apos;)</deletedAxiom>
<newAxiom>&apos;positive regulation of cell adhesion&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;cell adhesion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0080156</classIRI>
<classLabel>mitochondrial mRNA modification</classLabel>
<newAxiom>&apos;mitochondrial mRNA modification&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0080185</classIRI>
<classLabel>effector-dependent induction by symbiont of host immune response</classLabel>
<deletedAxiom>&apos;effector-dependent induction by symbiont of host immune response&apos; SubClassOf &apos;induction by symbiont of host immune response&apos;</deletedAxiom>
<newAxiom>&apos;effector-dependent induction by symbiont of host immune response&apos; SubClassOf &apos;positive regulation by symbiont of host programmed cell death&apos;</newAxiom>
<newAxiom>&apos;effector-dependent induction by symbiont of host immune response&apos; SubClassOf &apos;modulation by symbiont of host resistance gene-dependent defense response&apos;</newAxiom>
<newAxiom>&apos;effector-dependent induction by symbiont of host immune response&apos; SubClassOf &apos;induction by symbiont of host innate immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031048</classIRI>
<classLabel>chromatin silencing by small RNA</classLabel>
<deletedAxiom>&apos;chromatin silencing by small RNA&apos; EquivalentTo &apos;chromatin silencing&apos; and (&apos;mediated_by&apos; some &apos;snRNA&apos;)</deletedAxiom>
<deletedAxiom>&apos;chromatin silencing by small RNA&apos; SubClassOf &apos;mediated_by&apos; some &apos;snRNA&apos;</deletedAxiom>
<newAxiom>&apos;chromatin silencing by small RNA&apos; SubClassOf &apos;has causal agent&apos; some &apos;snRNA&apos;</newAxiom>
<newAxiom>&apos;chromatin silencing by small RNA&apos; EquivalentTo &apos;chromatin silencing&apos; and (&apos;has causal agent&apos; some &apos;snRNA&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031047</classIRI>
<classLabel>gene silencing by RNA</classLabel>
<deletedAxiom>&apos;gene silencing by RNA&apos; SubClassOf &apos;mediated_by&apos; some &apos;ribonucleic acid&apos;</deletedAxiom>
<deletedAxiom>&apos;gene silencing by RNA&apos; EquivalentTo &apos;gene silencing&apos; and (&apos;mediated_by&apos; some &apos;ribonucleic acid&apos;)</deletedAxiom>
<newAxiom>&apos;gene silencing by RNA&apos; SubClassOf &apos;has causal agent&apos; some &apos;ribonucleic acid&apos;</newAxiom>
<newAxiom>&apos;gene silencing by RNA&apos; EquivalentTo &apos;gene silencing&apos; and (&apos;has causal agent&apos; some &apos;ribonucleic acid&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070643</classIRI>
<classLabel>vitamin D 25-hydroxylase activity</classLabel>
<deletedAxiom>&apos;vitamin D 25-hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity&apos;</deletedAxiom>
<newAxiom>&apos;vitamin D 25-hydroxylase activity&apos; SubClassOf &apos;monooxygenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033577</classIRI>
<classLabel>protein glycosylation in endoplasmic reticulum</classLabel>
<newAxiom>&apos;protein glycosylation in endoplasmic reticulum&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;protein glycosylation in endoplasmic reticulum&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033579</classIRI>
<classLabel>protein galactosylation in endoplasmic reticulum</classLabel>
<newAxiom>&apos;protein galactosylation in endoplasmic reticulum&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033578</classIRI>
<classLabel>protein glycosylation in Golgi</classLabel>
<newAxiom>&apos;protein glycosylation in Golgi&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;protein glycosylation in Golgi&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033581</classIRI>
<classLabel>protein galactosylation in Golgi</classLabel>
<newAxiom>&apos;protein galactosylation in Golgi&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033584</classIRI>
<classLabel>tyrosine biosynthetic process from chorismate via L-arogenate</classLabel>
<deletedAxiom>&apos;tyrosine biosynthetic process from chorismate via L-arogenate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;L-arogenate(1-)&apos;) and (&apos;has primary output&apos; some &apos;tyrosine&apos;) and (&apos;has primary input&apos; some &apos;chorismate(2-)&apos;)</deletedAxiom>
<deletedAxiom>&apos;tyrosine biosynthetic process from chorismate via L-arogenate&apos; SubClassOf &apos;has intermediate&apos; some &apos;L-arogenate(1-)&apos;</deletedAxiom>
<newAxiom>&apos;tyrosine biosynthetic process from chorismate via L-arogenate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;L-arogenate(1-)&apos;</newAxiom>
<newAxiom>&apos;tyrosine biosynthetic process from chorismate via L-arogenate&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;L-arogenate(1-)&apos;) and (&apos;has primary output&apos; some &apos;tyrosine&apos;) and (&apos;has primary input&apos; some &apos;chorismate(2-)&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033586</classIRI>
<classLabel>L-phenylalanine biosynthetic process from chorismate via L-arogenate</classLabel>
<deletedAxiom>&apos;L-phenylalanine biosynthetic process from chorismate via L-arogenate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;L-arogenate(1-)&apos;) and (&apos;has primary output&apos; some &apos;L-phenylalaninate&apos;) and (&apos;has primary input&apos; some &apos;chorismate(2-)&apos;)</deletedAxiom>
<deletedAxiom>&apos;L-phenylalanine biosynthetic process from chorismate via L-arogenate&apos; SubClassOf &apos;has intermediate&apos; some &apos;L-arogenate(1-)&apos;</deletedAxiom>
<newAxiom>&apos;L-phenylalanine biosynthetic process from chorismate via L-arogenate&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;L-arogenate(1-)&apos;) and (&apos;has primary output&apos; some &apos;L-phenylalaninate&apos;) and (&apos;has primary input&apos; some &apos;chorismate(2-)&apos;)</newAxiom>
<newAxiom>&apos;L-phenylalanine biosynthetic process from chorismate via L-arogenate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;L-arogenate(1-)&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033585</classIRI>
<classLabel>L-phenylalanine biosynthetic process from chorismate via phenylpyruvate</classLabel>
<deletedAxiom>&apos;L-phenylalanine biosynthetic process from chorismate via phenylpyruvate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;keto-phenylpyruvic acid&apos;) and (&apos;has primary output&apos; some &apos;L-phenylalaninate&apos;) and (&apos;has primary input&apos; some &apos;chorismate(2-)&apos;)</deletedAxiom>
<deletedAxiom>&apos;L-phenylalanine biosynthetic process from chorismate via phenylpyruvate&apos; SubClassOf &apos;has intermediate&apos; some &apos;keto-phenylpyruvic acid&apos;</deletedAxiom>
<newAxiom>&apos;L-phenylalanine biosynthetic process from chorismate via phenylpyruvate&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;keto-phenylpyruvic acid&apos;) and (&apos;has primary output&apos; some &apos;L-phenylalaninate&apos;) and (&apos;has primary input&apos; some &apos;chorismate(2-)&apos;)</newAxiom>
<newAxiom>&apos;L-phenylalanine biosynthetic process from chorismate via phenylpyruvate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;keto-phenylpyruvic acid&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033516</classIRI>
<classLabel>L-methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine</classLabel>
<deletedAxiom>&apos;L-methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine&apos; SubClassOf &apos;has intermediate&apos; some &apos;O-phospho-L-homoserine&apos;</deletedAxiom>
<deletedAxiom>&apos;L-methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;O-phospho-L-homoserine&apos;) and (&apos;has primary output&apos; some &apos;L-methionine&apos;) and (&apos;has primary input&apos; some &apos;L-homoserine&apos;)</deletedAxiom>
<newAxiom>&apos;L-methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;O-phospho-L-homoserine&apos;) and (&apos;has primary output&apos; some &apos;L-methionine&apos;) and (&apos;has primary input&apos; some &apos;L-homoserine&apos;)</newAxiom>
<newAxiom>&apos;L-methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;O-phospho-L-homoserine&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033546</classIRI>
<classLabel>myo-inositol hexakisphosphate biosynthetic process, via inositol 1,3,4-trisphosphate</classLabel>
<deletedAxiom>&apos;myo-inositol hexakisphosphate biosynthetic process, via inositol 1,3,4-trisphosphate&apos; SubClassOf &apos;has intermediate&apos; some &apos;1D-myo-inositol 1,3,4-trisphosphate&apos;</deletedAxiom>
<deletedAxiom>&apos;myo-inositol hexakisphosphate biosynthetic process, via inositol 1,3,4-trisphosphate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;1D-myo-inositol 1,3,4-trisphosphate&apos;) and (&apos;has primary output&apos; some &apos;myo-inositol hexakisphosphate&apos;)</deletedAxiom>
<newAxiom>&apos;myo-inositol hexakisphosphate biosynthetic process, via inositol 1,3,4-trisphosphate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;1D-myo-inositol 1,3,4-trisphosphate&apos;</newAxiom>
<newAxiom>&apos;myo-inositol hexakisphosphate biosynthetic process, via inositol 1,3,4-trisphosphate&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;1D-myo-inositol 1,3,4-trisphosphate&apos;) and (&apos;has primary output&apos; some &apos;myo-inositol hexakisphosphate&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033498</classIRI>
<classLabel>galactose catabolic process via D-galactonate</classLabel>
<deletedAxiom>&apos;galactose catabolic process via D-galactonate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some &apos;D-galactonate&apos;) and (&apos;has primary input&apos; some &apos;galactose&apos;)</deletedAxiom>
<deletedAxiom>&apos;galactose catabolic process via D-galactonate&apos; SubClassOf &apos;has intermediate&apos; some &apos;D-galactonate&apos;</deletedAxiom>
<newAxiom>&apos;galactose catabolic process via D-galactonate&apos; EquivalentTo &apos;catabolic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;D-galactonate&apos;) and (&apos;has primary input&apos; some &apos;galactose&apos;)</newAxiom>
<newAxiom>&apos;galactose catabolic process via D-galactonate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;D-galactonate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033499</classIRI>
<classLabel>galactose catabolic process via UDP-galactose</classLabel>
<deletedAxiom>&apos;galactose catabolic process via UDP-galactose&apos; SubClassOf &apos;has intermediate&apos; some &apos;UDP-D-galactose&apos;</deletedAxiom>
<deletedAxiom>&apos;galactose catabolic process via UDP-galactose&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some &apos;UDP-D-galactose&apos;) and (&apos;has primary input&apos; some &apos;galactose&apos;)</deletedAxiom>
<newAxiom>&apos;galactose catabolic process via UDP-galactose&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;UDP-D-galactose&apos;</newAxiom>
<newAxiom>&apos;galactose catabolic process via UDP-galactose&apos; EquivalentTo &apos;catabolic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;UDP-D-galactose&apos;) and (&apos;has primary input&apos; some &apos;galactose&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033490</classIRI>
<classLabel>cholesterol biosynthetic process via lathosterol</classLabel>
<deletedAxiom>&apos;cholesterol biosynthetic process via lathosterol&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;5alpha-cholest-7-en-3beta-ol&apos;) and (&apos;has primary output&apos; some &apos;cholesterol&apos;)</deletedAxiom>
<deletedAxiom>&apos;cholesterol biosynthetic process via lathosterol&apos; SubClassOf &apos;has intermediate&apos; some &apos;5alpha-cholest-7-en-3beta-ol&apos;</deletedAxiom>
<newAxiom>&apos;cholesterol biosynthetic process via lathosterol&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;5alpha-cholest-7-en-3beta-ol&apos;) and (&apos;has primary output&apos; some &apos;cholesterol&apos;)</newAxiom>
<newAxiom>&apos;cholesterol biosynthetic process via lathosterol&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;5alpha-cholest-7-en-3beta-ol&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033489</classIRI>
<classLabel>cholesterol biosynthetic process via desmosterol</classLabel>
<deletedAxiom>&apos;cholesterol biosynthetic process via desmosterol&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;desmosterol&apos;) and (&apos;has primary output&apos; some &apos;cholesterol&apos;)</deletedAxiom>
<deletedAxiom>&apos;cholesterol biosynthetic process via desmosterol&apos; SubClassOf &apos;has intermediate&apos; some &apos;desmosterol&apos;</deletedAxiom>
<newAxiom>&apos;cholesterol biosynthetic process via desmosterol&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;desmosterol&apos;) and (&apos;has primary output&apos; some &apos;cholesterol&apos;)</newAxiom>
<newAxiom>&apos;cholesterol biosynthetic process via desmosterol&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;desmosterol&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033488</classIRI>
<classLabel>cholesterol biosynthetic process via 24,25-dihydrolanosterol</classLabel>
<deletedAxiom>&apos;cholesterol biosynthetic process via 24,25-dihydrolanosterol&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;24,25-dihydrolanosterol&apos;) and (&apos;has primary output&apos; some &apos;cholesterol&apos;)</deletedAxiom>
<deletedAxiom>&apos;cholesterol biosynthetic process via 24,25-dihydrolanosterol&apos; SubClassOf &apos;has intermediate&apos; some &apos;24,25-dihydrolanosterol&apos;</deletedAxiom>
<newAxiom>&apos;cholesterol biosynthetic process via 24,25-dihydrolanosterol&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;24,25-dihydrolanosterol&apos;) and (&apos;has primary output&apos; some &apos;cholesterol&apos;)</newAxiom>
<newAxiom>&apos;cholesterol biosynthetic process via 24,25-dihydrolanosterol&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;24,25-dihydrolanosterol&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008403</classIRI>
<classLabel>25-hydroxycholecalciferol-24-hydroxylase activity</classLabel>
<deletedAxiom>&apos;25-hydroxycholecalciferol-24-hydroxylase activity&apos; SubClassOf &apos;monooxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033325</classIRI>
<classLabel>choline biosynthetic process via phosphoryl-ethanolamine</classLabel>
<deletedAxiom>&apos;choline biosynthetic process via phosphoryl-ethanolamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;O-phosphonatoethanaminium(1-)&apos;) and (&apos;has primary output&apos; some &apos;choline&apos;)</deletedAxiom>
<deletedAxiom>&apos;choline biosynthetic process via phosphoryl-ethanolamine&apos; SubClassOf &apos;has intermediate&apos; some &apos;O-phosphonatoethanaminium(1-)&apos;</deletedAxiom>
<newAxiom>&apos;choline biosynthetic process via phosphoryl-ethanolamine&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;O-phosphonatoethanaminium(1-)&apos;</newAxiom>
<newAxiom>&apos;choline biosynthetic process via phosphoryl-ethanolamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;O-phosphonatoethanaminium(1-)&apos;) and (&apos;has primary output&apos; some &apos;choline&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033317</classIRI>
<classLabel>pantothenate biosynthetic process from valine</classLabel>
<deletedAxiom>&apos;pantothenate biosynthetic process from valine&apos; SubClassOf &apos;has primary input&apos; some &apos;valinate&apos;</deletedAxiom>
<deletedAxiom>&apos;pantothenate biosynthetic process from valine&apos; SubClassOf &apos;pantothenate biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;pantothenate biosynthetic process from valine&apos; SubClassOf &apos;valine metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;pantothenate biosynthetic process from valine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some &apos;pantothenate&apos;) and (&apos;has primary input&apos; some &apos;valinate&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033318</classIRI>
<classLabel>pantothenate biosynthetic process from 2-dehydropantolactone</classLabel>
<deletedAxiom>&apos;pantothenate biosynthetic process from 2-dehydropantolactone&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some &apos;pantothenate&apos;) and (&apos;has primary input&apos; some &apos;2-dehydropantolactone&apos;)</deletedAxiom>
<deletedAxiom>&apos;pantothenate biosynthetic process from 2-dehydropantolactone&apos; SubClassOf &apos;heterocycle metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;pantothenate biosynthetic process from 2-dehydropantolactone&apos; SubClassOf &apos;has primary input&apos; some &apos;2-dehydropantolactone&apos;</deletedAxiom>
<deletedAxiom>&apos;pantothenate biosynthetic process from 2-dehydropantolactone&apos; SubClassOf &apos;pantothenate biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;pantothenate biosynthetic process from 2-dehydropantolactone&apos; SubClassOf &apos;organic cyclic compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033324</classIRI>
<classLabel>choline biosynthetic process via N-monomethylethanolamine</classLabel>
<deletedAxiom>&apos;choline biosynthetic process via N-monomethylethanolamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;N-methylethanolamine&apos;) and (&apos;has primary output&apos; some &apos;choline&apos;)</deletedAxiom>
<deletedAxiom>&apos;choline biosynthetic process via N-monomethylethanolamine&apos; SubClassOf &apos;has intermediate&apos; some &apos;N-methylethanolamine&apos;</deletedAxiom>
<newAxiom>&apos;choline biosynthetic process via N-monomethylethanolamine&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;N-methylethanolamine&apos;</newAxiom>
<newAxiom>&apos;choline biosynthetic process via N-monomethylethanolamine&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;N-methylethanolamine&apos;) and (&apos;has primary output&apos; some &apos;choline&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033323</classIRI>
<classLabel>choline biosynthetic process via CDP-choline</classLabel>
<deletedAxiom>&apos;choline biosynthetic process via CDP-choline&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;CDP-choline&apos;) and (&apos;has primary output&apos; some &apos;choline&apos;)</deletedAxiom>
<deletedAxiom>&apos;choline biosynthetic process via CDP-choline&apos; SubClassOf &apos;has intermediate&apos; some &apos;CDP-choline&apos;</deletedAxiom>
<newAxiom>&apos;choline biosynthetic process via CDP-choline&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;CDP-choline&apos;</newAxiom>
<newAxiom>&apos;choline biosynthetic process via CDP-choline&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;CDP-choline&apos;) and (&apos;has primary output&apos; some &apos;choline&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033353</classIRI>
<classLabel>S-adenosylmethionine cycle</classLabel>
<deletedAxiom>&apos;S-adenosylmethionine cycle&apos; SubClassOf &apos;cellular modified amino acid metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033346</classIRI>
<classLabel>asparagine catabolic process via 2-oxosuccinamate</classLabel>
<deletedAxiom>&apos;asparagine catabolic process via 2-oxosuccinamate&apos; SubClassOf &apos;has intermediate&apos; some &apos;2-oxosuccinamate&apos;</deletedAxiom>
<deletedAxiom>&apos;asparagine catabolic process via 2-oxosuccinamate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some &apos;2-oxosuccinamate&apos;) and (&apos;has primary input&apos; some &apos;asparaginate&apos;)</deletedAxiom>
<newAxiom>&apos;asparagine catabolic process via 2-oxosuccinamate&apos; EquivalentTo &apos;catabolic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;2-oxosuccinamate&apos;) and (&apos;has primary input&apos; some &apos;asparaginate&apos;)</newAxiom>
<newAxiom>&apos;asparagine catabolic process via 2-oxosuccinamate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;2-oxosuccinamate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033345</classIRI>
<classLabel>asparagine catabolic process via L-aspartate</classLabel>
<deletedAxiom>&apos;asparagine catabolic process via L-aspartate&apos; SubClassOf &apos;has intermediate&apos; some &apos;L-aspartate(2-)&apos;</deletedAxiom>
<deletedAxiom>&apos;asparagine catabolic process via L-aspartate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has intermediate&apos; some &apos;L-aspartate(2-)&apos;) and (&apos;has primary input&apos; some &apos;asparaginate&apos;)</deletedAxiom>
<newAxiom>&apos;asparagine catabolic process via L-aspartate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;L-aspartate(2-)&apos;</newAxiom>
<newAxiom>&apos;asparagine catabolic process via L-aspartate&apos; EquivalentTo &apos;catabolic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;L-aspartate(2-)&apos;) and (&apos;has primary input&apos; some &apos;asparaginate&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033359</classIRI>
<classLabel>lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate</classLabel>
<deletedAxiom>&apos;lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;L-2-succinylamino-6-oxoheptanedioate(3-)&apos;) and (&apos;has intermediate&apos; some &apos;2,6-diaminopimelate(2-)&apos;) and (&apos;has primary output&apos; some &apos;lysinate&apos;)</deletedAxiom>
<deletedAxiom>&apos;lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate&apos; SubClassOf &apos;has intermediate&apos; some &apos;L-2-succinylamino-6-oxoheptanedioate(3-)&apos;</deletedAxiom>
<newAxiom>&apos;lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;L-2-succinylamino-6-oxoheptanedioate(3-)&apos;) and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;2,6-diaminopimelate(2-)&apos;) and (&apos;has primary output&apos; some &apos;lysinate&apos;)</newAxiom>
<newAxiom>&apos;lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;L-2-succinylamino-6-oxoheptanedioate(3-)&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033362</classIRI>
<classLabel>lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway</classLabel>
<deletedAxiom>&apos;lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has_part&apos; some &apos;diaminopimelate epimerase activity&apos;) and (&apos;has_part&apos; some &apos;L,L-diaminopimelate aminotransferase activity&apos;) and (&apos;has intermediate&apos; some &apos;2,6-diaminopimelate(2-)&apos;) and (&apos;has primary output&apos; some &apos;lysinate&apos;)</deletedAxiom>
<newAxiom>&apos;lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has_part&apos; some &apos;diaminopimelate epimerase activity&apos;) and (&apos;has_part&apos; some &apos;L,L-diaminopimelate aminotransferase activity&apos;) and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;2,6-diaminopimelate(2-)&apos;) and (&apos;has primary output&apos; some &apos;lysinate&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033361</classIRI>
<classLabel>lysine biosynthetic process via diaminopimelate, dehydrogenase pathway</classLabel>
<deletedAxiom>&apos;lysine biosynthetic process via diaminopimelate, dehydrogenase pathway&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has_part&apos; some &apos;diaminopimelate dehydrogenase activity&apos;) and (&apos;has intermediate&apos; some &apos;2,6-diaminopimelate(2-)&apos;) and (&apos;has primary output&apos; some &apos;lysinate&apos;)</deletedAxiom>
<newAxiom>&apos;lysine biosynthetic process via diaminopimelate, dehydrogenase pathway&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has_part&apos; some &apos;diaminopimelate dehydrogenase activity&apos;) and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;2,6-diaminopimelate(2-)&apos;) and (&apos;has primary output&apos; some &apos;lysinate&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033360</classIRI>
<classLabel>lysine biosynthetic process via diaminopimelate and L-2-acetamido-6-oxoheptanedioate</classLabel>
<deletedAxiom>&apos;lysine biosynthetic process via diaminopimelate and L-2-acetamido-6-oxoheptanedioate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;(S)-2-acetamido-6-oxopimelic acid&apos;) and (&apos;has intermediate&apos; some &apos;2,6-diaminopimelate(2-)&apos;) and (&apos;has primary output&apos; some &apos;lysinate&apos;)</deletedAxiom>
<deletedAxiom>&apos;lysine biosynthetic process via diaminopimelate and L-2-acetamido-6-oxoheptanedioate&apos; SubClassOf &apos;has intermediate&apos; some &apos;(S)-2-acetamido-6-oxopimelic acid&apos;</deletedAxiom>
<newAxiom>&apos;lysine biosynthetic process via diaminopimelate and L-2-acetamido-6-oxoheptanedioate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;(S)-2-acetamido-6-oxopimelic acid&apos;</newAxiom>
<newAxiom>&apos;lysine biosynthetic process via diaminopimelate and L-2-acetamido-6-oxoheptanedioate&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;(S)-2-acetamido-6-oxopimelic acid&apos;) and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;2,6-diaminopimelate(2-)&apos;) and (&apos;has primary output&apos; some &apos;lysinate&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033395</classIRI>
<classLabel>beta-alanine biosynthetic process via 3-hydroxypropionate</classLabel>
<deletedAxiom>&apos;beta-alanine biosynthetic process via 3-hydroxypropionate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;3-hydroxypropionate&apos;) and (&apos;has primary output&apos; some &apos;beta-alanine&apos;)</deletedAxiom>
<deletedAxiom>&apos;beta-alanine biosynthetic process via 3-hydroxypropionate&apos; SubClassOf &apos;has intermediate&apos; some &apos;3-hydroxypropionate&apos;</deletedAxiom>
<newAxiom>&apos;beta-alanine biosynthetic process via 3-hydroxypropionate&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;3-hydroxypropionate&apos;) and (&apos;has primary output&apos; some &apos;beta-alanine&apos;)</newAxiom>
<newAxiom>&apos;beta-alanine biosynthetic process via 3-hydroxypropionate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;3-hydroxypropionate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033394</classIRI>
<classLabel>beta-alanine biosynthetic process via 1,3 diaminopropane</classLabel>
<deletedAxiom>&apos;beta-alanine biosynthetic process via 1,3 diaminopropane&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;trimethylenediamine&apos;) and (&apos;has primary output&apos; some &apos;beta-alanine&apos;)</deletedAxiom>
<deletedAxiom>&apos;beta-alanine biosynthetic process via 1,3 diaminopropane&apos; SubClassOf &apos;has intermediate&apos; some &apos;trimethylenediamine&apos;</deletedAxiom>
<newAxiom>&apos;beta-alanine biosynthetic process via 1,3 diaminopropane&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;trimethylenediamine&apos;</newAxiom>
<newAxiom>&apos;beta-alanine biosynthetic process via 1,3 diaminopropane&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;trimethylenediamine&apos;) and (&apos;has primary output&apos; some &apos;beta-alanine&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033396</classIRI>
<classLabel>beta-alanine biosynthetic process via 3-ureidopropionate</classLabel>
<deletedAxiom>&apos;beta-alanine biosynthetic process via 3-ureidopropionate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;N-carbamoyl-beta-alaninate&apos;) and (&apos;has primary output&apos; some &apos;beta-alanine&apos;)</deletedAxiom>
<deletedAxiom>&apos;beta-alanine biosynthetic process via 3-ureidopropionate&apos; SubClassOf &apos;has intermediate&apos; some &apos;N-carbamoyl-beta-alaninate&apos;</deletedAxiom>
<newAxiom>&apos;beta-alanine biosynthetic process via 3-ureidopropionate&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;N-carbamoyl-beta-alaninate&apos;) and (&apos;has primary output&apos; some &apos;beta-alanine&apos;)</newAxiom>
<newAxiom>&apos;beta-alanine biosynthetic process via 3-ureidopropionate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;N-carbamoyl-beta-alaninate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033390</classIRI>
<classLabel>putrescine biosynthetic process from arginine via N-carbamoylputrescine</classLabel>
<deletedAxiom>&apos;putrescine biosynthetic process from arginine via N-carbamoylputrescine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;N-carbamoylputrescine&apos;) and (&apos;has primary output&apos; some &apos;putrescine&apos;) and (&apos;has primary input&apos; some &apos;argininate&apos;)</deletedAxiom>
<deletedAxiom>&apos;putrescine biosynthetic process from arginine via N-carbamoylputrescine&apos; SubClassOf &apos;has intermediate&apos; some &apos;N-carbamoylputrescine&apos;</deletedAxiom>
<newAxiom>&apos;putrescine biosynthetic process from arginine via N-carbamoylputrescine&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;N-carbamoylputrescine&apos;) and (&apos;has primary output&apos; some &apos;putrescine&apos;) and (&apos;has primary input&apos; some &apos;argininate&apos;)</newAxiom>
<newAxiom>&apos;putrescine biosynthetic process from arginine via N-carbamoylputrescine&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;N-carbamoylputrescine&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033389</classIRI>
<classLabel>putrescine biosynthetic process from arginine, using agmatinase</classLabel>
<deletedAxiom>&apos;putrescine biosynthetic process from arginine, using agmatinase&apos; SubClassOf &apos;has intermediate&apos; some &apos;agmatine&apos;</deletedAxiom>
<deletedAxiom>&apos;putrescine biosynthetic process from arginine, using agmatinase&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;agmatine&apos;) and (&apos;has primary output&apos; some &apos;putrescine&apos;) and (&apos;has primary input&apos; some &apos;argininate&apos;)</deletedAxiom>
<newAxiom>&apos;putrescine biosynthetic process from arginine, using agmatinase&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;agmatine&apos;) and (&apos;has primary output&apos; some &apos;putrescine&apos;) and (&apos;has primary input&apos; some &apos;argininate&apos;)</newAxiom>
<newAxiom>&apos;putrescine biosynthetic process from arginine, using agmatinase&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;agmatine&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008316</classIRI>
<classLabel>structural constituent of vitelline membrane</classLabel>
<newAxiom>&apos;structural constituent of vitelline membrane&apos; SubClassOf &apos;in taxon&apos; only &apos;Bilateria&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008333</classIRI>
<classLabel>endosome to lysosome transport</classLabel>
<deletedAxiom>&apos;endosome to lysosome transport&apos; EquivalentTo &apos;intracellular transport&apos; and (&apos;mediated_by&apos; some &apos;vesicle&apos;) and (&apos;has target start location&apos; some &apos;endosome&apos;) and (&apos;has target end location&apos; some &apos;lysosome&apos;)</deletedAxiom>
<newAxiom>&apos;endosome to lysosome transport&apos; EquivalentTo &apos;intracellular transport&apos; and (&apos;has target start location&apos; some &apos;endosome&apos;) and (&apos;has target end location&apos; some &apos;lysosome&apos;) and (&apos;has causal agent&apos; some &apos;vesicle&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033311</classIRI>
<classLabel>chlorophyll a biosynthetic process via phytyl diphosphate</classLabel>
<deletedAxiom>&apos;chlorophyll a biosynthetic process via phytyl diphosphate&apos; SubClassOf &apos;has intermediate&apos; some &apos;(E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate&apos;</deletedAxiom>
<deletedAxiom>&apos;chlorophyll a biosynthetic process via phytyl diphosphate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;(E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate&apos;) and (&apos;has primary output&apos; some &apos;chlorophyll a&apos;)</deletedAxiom>
<newAxiom>&apos;chlorophyll a biosynthetic process via phytyl diphosphate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;(E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate&apos;</newAxiom>
<newAxiom>&apos;chlorophyll a biosynthetic process via phytyl diphosphate&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;(E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate&apos;) and (&apos;has primary output&apos; some &apos;chlorophyll a&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033312</classIRI>
<classLabel>chlorophyll a biosynthetic process via geranylgeranyl-chlorophyll a</classLabel>
<deletedAxiom>&apos;chlorophyll a biosynthetic process via geranylgeranyl-chlorophyll a&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;geranylgeranyl-chlorophyll a&apos;) and (&apos;has primary output&apos; some &apos;chlorophyll a&apos;)</deletedAxiom>
<deletedAxiom>&apos;chlorophyll a biosynthetic process via geranylgeranyl-chlorophyll a&apos; SubClassOf &apos;has intermediate&apos; some &apos;geranylgeranyl-chlorophyll a&apos;</deletedAxiom>
<newAxiom>&apos;chlorophyll a biosynthetic process via geranylgeranyl-chlorophyll a&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;geranylgeranyl-chlorophyll a&apos;</newAxiom>
<newAxiom>&apos;chlorophyll a biosynthetic process via geranylgeranyl-chlorophyll a&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;geranylgeranyl-chlorophyll a&apos;) and (&apos;has primary output&apos; some &apos;chlorophyll a&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033259</classIRI>
<classLabel>plastid DNA replication</classLabel>
<newAxiom>&apos;plastid DNA replication&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Metazoa&apos;))</newAxiom>
<newAxiom>&apos;plastid DNA replication&apos; DisjointWith &apos;in taxon&apos; some &apos;Bacteria&apos;</newAxiom>
<newAxiom>&apos;plastid DNA replication&apos; DisjointWith &apos;in taxon&apos; some &apos;Metazoa&apos;</newAxiom>
<newAxiom>&apos;plastid DNA replication&apos; DisjointWith &apos;in taxon&apos; some &apos;Choanoflagellata&apos;</newAxiom>
<newAxiom>&apos;plastid DNA replication&apos; DisjointWith &apos;in taxon&apos; some &apos;Amoebozoa&apos;</newAxiom>
<newAxiom>&apos;plastid DNA replication&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Amoebozoa&apos;))</newAxiom>
<newAxiom>&apos;plastid DNA replication&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Choanoflagellata&apos;))</newAxiom>
<newAxiom>&apos;plastid DNA replication&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Archaea&apos;))</newAxiom>
<newAxiom>&apos;plastid DNA replication&apos; DisjointWith &apos;in taxon&apos; some &apos;Fungi&apos;</newAxiom>
<newAxiom>&apos;plastid DNA replication&apos; DisjointWith &apos;in taxon&apos; some &apos;Archaea&apos;</newAxiom>
<newAxiom>&apos;plastid DNA replication&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Bacteria&apos;))</newAxiom>
<newAxiom>&apos;plastid DNA replication&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Fungi&apos;))</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033260</classIRI>
<classLabel>nuclear DNA replication</classLabel>
<newAxiom>&apos;nuclear DNA replication&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;nuclear DNA replication&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008147</classIRI>
<classLabel>structural constituent of bone</classLabel>
<newAxiom>&apos;structural constituent of bone&apos; SubClassOf &apos;in taxon&apos; only &apos;Vertebrata vertebrates&apos;</newAxiom>
<newAxiom>&apos;structural constituent of bone&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Vertebrata vertebrates&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072656</classIRI>
<classLabel>maintenance of protein location in mitochondrion</classLabel>
<newAxiom>&apos;maintenance of protein location in mitochondrion&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;maintenance of protein location in mitochondrion&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072684</classIRI>
<classLabel>mitochondrial tRNA 3&apos;-trailer cleavage, endonucleolytic</classLabel>
<newAxiom>&apos;mitochondrial tRNA 3&apos;-trailer cleavage, endonucleolytic&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072597</classIRI>
<classLabel>maintenance of protein location in chloroplast</classLabel>
<newAxiom>&apos;maintenance of protein location in chloroplast&apos; DisjointWith &apos;in taxon&apos; some &apos;Choanoflagellata&apos;</newAxiom>
<newAxiom>&apos;maintenance of protein location in chloroplast&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Choanoflagellata&apos;))</newAxiom>
<newAxiom>&apos;maintenance of protein location in chloroplast&apos; DisjointWith &apos;in taxon&apos; some &apos;Amoebozoa&apos;</newAxiom>
<newAxiom>&apos;maintenance of protein location in chloroplast&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Fungi&apos;))</newAxiom>
<newAxiom>&apos;maintenance of protein location in chloroplast&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Metazoa&apos;))</newAxiom>
<newAxiom>&apos;maintenance of protein location in chloroplast&apos; DisjointWith &apos;in taxon&apos; some &apos;Metazoa&apos;</newAxiom>
<newAxiom>&apos;maintenance of protein location in chloroplast&apos; DisjointWith &apos;in taxon&apos; some &apos;Fungi&apos;</newAxiom>
<newAxiom>&apos;maintenance of protein location in chloroplast&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Amoebozoa&apos;))</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106220</classIRI>
<classLabel>pyocyanin biosynthetic process</classLabel>
<deletedAxiom>&apos;pyocyanin biosynthetic process&apos; SubClassOf &apos;phenazine biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;pyocyanin biosynthetic process&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some &apos;pyocyanine&apos;)</newAxiom>
<newAxiom>&apos;pyocyanin biosynthetic process&apos; SubClassOf &apos;organic cyclic compound biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;pyocyanin biosynthetic process&apos; SubClassOf &apos;heterocycle biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;pyocyanin biosynthetic process&apos; SubClassOf &apos;antibiotic biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;pyocyanin biosynthetic process&apos; SubClassOf &apos;toxin biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;pyocyanin biosynthetic process&apos; SubClassOf &apos;organonitrogen compound biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;pyocyanin biosynthetic process&apos; SubClassOf &apos;has primary output&apos; some &apos;pyocyanine&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052807</classIRI>
<classLabel>aflatoxin reductase (coenzyme F420) activity</classLabel>
<newAxiom>&apos;aflatoxin reductase (coenzyme F420) activity&apos; SubClassOf &apos;part of&apos; some &apos;aflatoxin catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052704</classIRI>
<classLabel>ergothioneine biosynthesis from histidine via N-alpha,N-alpha,N-alpha-trimethyl-L-histidine</classLabel>
<deletedAxiom>&apos;ergothioneine biosynthesis from histidine via N-alpha,N-alpha,N-alpha-trimethyl-L-histidine&apos; SubClassOf &apos;has intermediate&apos; some &apos;N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine&apos;</deletedAxiom>
<newAxiom>&apos;ergothioneine biosynthesis from histidine via N-alpha,N-alpha,N-alpha-trimethyl-L-histidine&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052527</classIRI>
<classLabel>positive regulation by symbiont of host resistance gene-dependent defense response</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host resistance gene-dependent defense response&apos; SubClassOf &apos;positive regulation by symbiont of host immune response&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host resistance gene-dependent defense response&apos; SubClassOf &apos;modulation by symbiont of host resistance gene-dependent defense response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052526</classIRI>
<classLabel>positive regulation by organism of signal transduction in other organism involved in symbiotic interaction</classLabel>
<deletedAxiom>&apos;positive regulation by organism of signal transduction in other organism involved in symbiotic interaction&apos; SubClassOf &apos;modulation of signal transduction in other organism involved in symbiotic interaction&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by organism of signal transduction in other organism involved in symbiotic interaction&apos; SubClassOf &apos;positive regulation of signal transduction in other organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052537</classIRI>
<classLabel>positive regulation by symbiont of host systemic acquired resistance</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host systemic acquired resistance&apos; SubClassOf &apos;modulation by symbiont of host systemic acquired resistance&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host systemic acquired resistance&apos; SubClassOf &apos;positive regulation by symbiont of host immune response&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host systemic acquired resistance&apos; SubClassOf &apos;positive regulation by symbiont of host defense response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052533</classIRI>
<classLabel>positive regulation by symbiont of host induced systemic resistance</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host induced systemic resistance&apos; SubClassOf &apos;positive regulation by symbiont of host defense response&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host induced systemic resistance&apos; SubClassOf &apos;modulation by symbiont of host induced systemic resistance&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host induced systemic resistance&apos; SubClassOf &apos;positive regulation by symbiont of host immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052539</classIRI>
<classLabel>positive regulation by symbiont of defense-related host cell wall thickening</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of defense-related host cell wall thickening&apos; SubClassOf &apos;modulation by symbiont of defense-related host cell wall thickening&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of defense-related host cell wall thickening&apos; SubClassOf &apos;positive regulation by symbiont of host defense response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052509</classIRI>
<classLabel>positive regulation by symbiont of host defense response</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host defense response&apos; SubClassOf &apos;modulation by symbiont of host defense response&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host defense response&apos; SubClassOf &apos;positive regulation of defense response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052565</classIRI>
<classLabel>response to defense-related host nitric oxide production</classLabel>
<newAxiom>&apos;response to defense-related host nitric oxide production&apos; SubClassOf &apos;cellular response to nitrosative stress&apos;</newAxiom>
<newAxiom>&apos;response to defense-related host nitric oxide production&apos; SubClassOf &apos;multi-organism cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052567</classIRI>
<classLabel>response to defense-related host reactive oxygen species production</classLabel>
<deletedAxiom>&apos;response to defense-related host reactive oxygen species production&apos; SubClassOf &apos;response to host immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052566</classIRI>
<classLabel>response to host phytoalexin production</classLabel>
<deletedAxiom>&apos;response to host phytoalexin production&apos; SubClassOf &apos;response to host immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052559</classIRI>
<classLabel>induction by symbiont of host immune response</classLabel>
<deletedAxiom>&apos;induction by symbiont of host immune response&apos; SubClassOf &apos;positive regulation by symbiont of host immune response&apos;</deletedAxiom>
<newAxiom>&apos;induction by symbiont of host immune response&apos; SubClassOf &apos;modulation by symbiont of host immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052553</classIRI>
<classLabel>modulation by symbiont of host immune response</classLabel>
<newAxiom>&apos;modulation by symbiont of host immune response&apos; DisjointWith &apos;in taxon&apos; some &apos;Metazoa&apos;</newAxiom>
<newAxiom>&apos;modulation by symbiont of host immune response&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Metazoa&apos;))</newAxiom>
<newAxiom>&apos;modulation by symbiont of host immune response&apos; DisjointWith &apos;in taxon&apos; some &apos;Viridiplantae&apos;</newAxiom>
<newAxiom>&apos;modulation by symbiont of host immune response&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Viridiplantae&apos;))</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052556</classIRI>
<classLabel>positive regulation by symbiont of host immune response</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host immune response&apos; SubClassOf &apos;modulation by symbiont of host immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990613</classIRI>
<classLabel>mitochondrial membrane fusion</classLabel>
<newAxiom>&apos;mitochondrial membrane fusion&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052493</classIRI>
<classLabel>negative regulation by organism of signal transduction in other organism involved in symbiotic interaction</classLabel>
<deletedAxiom>&apos;negative regulation by organism of signal transduction in other organism involved in symbiotic interaction&apos; SubClassOf &apos;modulation of signal transduction in other organism involved in symbiotic interaction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990770</classIRI>
<classLabel>small intestine smooth muscle contraction</classLabel>
<newAxiom>&apos;small intestine smooth muscle contraction&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Vertebrata vertebrates&apos;</newAxiom>
<newAxiom>&apos;small intestine smooth muscle contraction&apos; SubClassOf &apos;in taxon&apos; only &apos;Vertebrata vertebrates&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990765</classIRI>
<classLabel>colon smooth muscle contraction</classLabel>
<newAxiom>&apos;colon smooth muscle contraction&apos; SubClassOf &apos;in taxon&apos; only &apos;Vertebrata vertebrates&apos;</newAxiom>
<newAxiom>&apos;colon smooth muscle contraction&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Vertebrata vertebrates&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052369</classIRI>
<classLabel>positive regulation by symbiont of defense-related host reactive oxygen species production</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of defense-related host reactive oxygen species production&apos; SubClassOf &apos;modulation by symbiont of defense-related host reactive oxygen species production&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of defense-related host reactive oxygen species production&apos; SubClassOf &apos;positive regulation by symbiont of host defense response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052344</classIRI>
<classLabel>positive regulation by symbiont of host phytoalexin production</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host phytoalexin production&apos; SubClassOf &apos;positive regulation by symbiont of host immune response&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host phytoalexin production&apos; SubClassOf &apos;modulation by symbiont of host phytoalexin production&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation by symbiont of host phytoalexin production&apos; SubClassOf &apos;induction by symbiont of host immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052347</classIRI>
<classLabel>positive regulation by symbiont of defense-related host nitric oxide production</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of defense-related host nitric oxide production&apos; SubClassOf &apos;modulation by symbiont of defense-related host nitric oxide production&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of defense-related host nitric oxide production&apos; SubClassOf &apos;positive regulation by symbiont of host immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052389</classIRI>
<classLabel>positive regulation by symbiont of defense-related host calcium ion flux</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of defense-related host calcium ion flux&apos; SubClassOf &apos;modulation by symbiont of defense-related host calcium ion flux&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of defense-related host calcium ion flux&apos; SubClassOf &apos;positive regulation by symbiont of host defense response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052390</classIRI>
<classLabel>induction by symbiont of host innate immune response</classLabel>
<deletedAxiom>&apos;induction by symbiont of host innate immune response&apos; SubClassOf &apos;positive regulation by symbiont of host innate immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052391</classIRI>
<classLabel>induction by symbiont of defense-related host calcium ion flux</classLabel>
<deletedAxiom>&apos;induction by symbiont of defense-related host calcium ion flux&apos; SubClassOf &apos;positive regulation by symbiont of defense-related host calcium ion flux&apos;</deletedAxiom>
<newAxiom>&apos;induction by symbiont of defense-related host calcium ion flux&apos; SubClassOf &apos;modulation by symbiont of defense-related host calcium ion flux&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003341</classIRI>
<classLabel>cilium movement</classLabel>
<newAxiom>&apos;cilium movement&apos; EquivalentTo &apos;movement of cell or subcellular component&apos; and (&apos;results in movement of&apos; some &apos;cilium&apos;) and (&apos;has causal agent&apos; some &apos;microtubule&apos;)</newAxiom>
<newAxiom>&apos;cilium movement&apos; SubClassOf &apos;results in movement of&apos; some &apos;cilium&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052250</classIRI>
<classLabel>modulation of signal transduction in other organism involved in symbiotic interaction</classLabel>
<deletedAxiom>&apos;modulation of signal transduction in other organism involved in symbiotic interaction&apos; SubClassOf &apos;modification of morphology or physiology of other organism involved in symbiotic interaction&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation of signal transduction in other organism involved in symbiotic interaction&apos; SubClassOf &apos;modulation of signal transduction in other organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990813</classIRI>
<classLabel>meiotic centromeric cohesion protection</classLabel>
<newAxiom>&apos;meiotic centromeric cohesion protection&apos; SubClassOf &apos;part of&apos; some &apos;homologous chromosome segregation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052261</classIRI>
<classLabel>suppression of defense response of other organism involved in symbiotic interaction</classLabel>
<deletedAxiom>&apos;suppression of defense response of other organism involved in symbiotic interaction&apos; SubClassOf &apos;modulation by symbiont of host defense response&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression of defense response of other organism involved in symbiotic interaction&apos; SubClassOf &apos;negative regulation of defense response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052101</classIRI>
<classLabel>induction by symbiont of host resistance gene-dependent defense response</classLabel>
<deletedAxiom>&apos;induction by symbiont of host resistance gene-dependent defense response&apos; SubClassOf &apos;positive regulation by symbiont of host resistance gene-dependent defense response&apos;</deletedAxiom>
<deletedAxiom>&apos;induction by symbiont of host resistance gene-dependent defense response&apos; SubClassOf &apos;induction by symbiont of host immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042776</classIRI>
<classLabel>mitochondrial ATP synthesis coupled proton transport</classLabel>
<newAxiom>&apos;mitochondrial ATP synthesis coupled proton transport&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;mitochondrial ATP synthesis coupled proton transport&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042775</classIRI>
<classLabel>mitochondrial ATP synthesis coupled electron transport</classLabel>
<newAxiom>&apos;mitochondrial ATP synthesis coupled electron transport&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;mitochondrial ATP synthesis coupled electron transport&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902375</classIRI>
<classLabel>nuclear tRNA 3&apos;-trailer cleavage, endonucleolytic</classLabel>
<newAxiom>&apos;nuclear tRNA 3&apos;-trailer cleavage, endonucleolytic&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;nuclear tRNA 3&apos;-trailer cleavage, endonucleolytic&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052109</classIRI>
<classLabel>positive regulation by symbiont of defense-related host cell wall callose deposition</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of defense-related host cell wall callose deposition&apos; SubClassOf &apos;positive regulation by symbiont of defense-related host cell wall thickening&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation by symbiont of defense-related host cell wall callose deposition&apos; SubClassOf &apos;induction by symbiont of defense-related host cell wall thickening&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052103</classIRI>
<classLabel>induction by symbiont of host induced systemic resistance</classLabel>
<deletedAxiom>&apos;induction by symbiont of host induced systemic resistance&apos; SubClassOf &apos;positive regulation by symbiont of host induced systemic resistance&apos;</deletedAxiom>
<newAxiom>&apos;induction by symbiont of host induced systemic resistance&apos; SubClassOf &apos;modulation by symbiont of host induced systemic resistance&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052102</classIRI>
<classLabel>positive regulation by symbiont of defense-related host calcium-dependent protein kinase pathway</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of defense-related host calcium-dependent protein kinase pathway&apos; SubClassOf &apos;modulation by symbiont of host cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of defense-related host calcium-dependent protein kinase pathway&apos; SubClassOf &apos;positive regulation of calcium-mediated signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of defense-related host calcium-dependent protein kinase pathway&apos; SubClassOf &apos;positive regulation by symbiont of host defense response&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation by symbiont of defense-related host calcium-dependent protein kinase pathway&apos; SubClassOf &apos;induction by symbiont of host defense response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052105</classIRI>
<classLabel>induction by symbiont of defense-related host cell wall thickening</classLabel>
<deletedAxiom>&apos;induction by symbiont of defense-related host cell wall thickening&apos; SubClassOf &apos;positive regulation by symbiont of defense-related host cell wall thickening&apos;</deletedAxiom>
<newAxiom>&apos;induction by symbiont of defense-related host cell wall thickening&apos; SubClassOf &apos;modulation by symbiont of defense-related host cell wall thickening&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052104</classIRI>
<classLabel>induction by symbiont of host systemic acquired resistance</classLabel>
<deletedAxiom>&apos;induction by symbiont of host systemic acquired resistance&apos; SubClassOf &apos;positive regulation by symbiont of host systemic acquired resistance&apos;</deletedAxiom>
<newAxiom>&apos;induction by symbiont of host systemic acquired resistance&apos; SubClassOf &apos;modulation by symbiont of host systemic acquired resistance&apos;</newAxiom>
<newAxiom>&apos;induction by symbiont of host systemic acquired resistance&apos; SubClassOf &apos;induction by symbiont of host defense response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052170</classIRI>
<classLabel>negative regulation by symbiont of host innate immune response</classLabel>
<deletedAxiom>&apos;negative regulation by symbiont of host innate immune response&apos; SubClassOf &apos;negative regulation by symbiont of host defense response&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation by symbiont of host innate immune response&apos; SubClassOf &apos;suppression of host defenses&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052165</classIRI>
<classLabel>modulation by symbiont of host phytoalexin production</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host phytoalexin production&apos; SubClassOf &apos;response to host phytoalexin production&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by symbiont of host phytoalexin production&apos; SubClassOf &apos;modulation by symbiont of host immune response&apos;</deletedAxiom>
<newAxiom>&apos;modulation by symbiont of host phytoalexin production&apos; SubClassOf &apos;modulation by symbiont of host innate immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052164</classIRI>
<classLabel>modulation by symbiont of defense-related host reactive oxygen species production</classLabel>
<deletedAxiom>&apos;modulation by symbiont of defense-related host reactive oxygen species production&apos; SubClassOf &apos;modulation by symbiont of host immune response&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by symbiont of defense-related host reactive oxygen species production&apos; SubClassOf &apos;response to defense-related host reactive oxygen species production&apos;</deletedAxiom>
<newAxiom>&apos;modulation by symbiont of defense-related host reactive oxygen species production&apos; SubClassOf &apos;modulation by symbiont of host innate immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052166</classIRI>
<classLabel>positive regulation by symbiont of host innate immune response</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host innate immune response&apos; SubClassOf &apos;positive regulation by symbiont of host defense response&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host innate immune response&apos; SubClassOf &apos;modulation by symbiont of host innate immune response&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host innate immune response&apos; SubClassOf &apos;positive regulation by symbiont of host immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052163</classIRI>
<classLabel>modulation by symbiont of defense-related host nitric oxide production</classLabel>
<deletedAxiom>&apos;modulation by symbiont of defense-related host nitric oxide production&apos; SubClassOf &apos;modulation by symbiont of host immune response&apos;</deletedAxiom>
<newAxiom>&apos;modulation by symbiont of defense-related host nitric oxide production&apos; SubClassOf &apos;modulation by symbiont of host innate immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052076</classIRI>
<classLabel>positive regulation by symbiont of host ethylene-mediated defense response</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host ethylene-mediated defense response&apos; SubClassOf &apos;positive regulation by symbiont of host defense response&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation by symbiont of host ethylene-mediated defense response&apos; SubClassOf &apos;induction by symbiont of host defense response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052079</classIRI>
<classLabel>positive regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway&apos; SubClassOf &apos;positive regulation by symbiont of host defense response&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway&apos; SubClassOf &apos;induction by symbiont of host defense response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052078</classIRI>
<classLabel>negative regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway</classLabel>
<deletedAxiom>&apos;negative regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway&apos; SubClassOf &apos;negative regulation by symbiont of host defense response&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway&apos; SubClassOf &apos;suppression of host defenses&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052073</classIRI>
<classLabel>positive regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway</classLabel>
<newAxiom>&apos;positive regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway&apos; SubClassOf &apos;modulation by symbiont of host jasmonic acid-mediated defense response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052075</classIRI>
<classLabel>positive regulation by symbiont of host jasmonic acid-mediated defense response</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host jasmonic acid-mediated defense response&apos; SubClassOf &apos;positive regulation by symbiont of host defense response&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host jasmonic acid-mediated defense response&apos; SubClassOf &apos;positive regulation by symbiont of host immune response&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host jasmonic acid-mediated defense response&apos; SubClassOf &apos;modulation by symbiont of host jasmonic acid-mediated defense response&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation by symbiont of host jasmonic acid-mediated defense response&apos; SubClassOf &apos;induction by symbiont of host defense response&apos;</newAxiom>
<newAxiom>&apos;positive regulation by symbiont of host jasmonic acid-mediated defense response&apos; SubClassOf &apos;induction by symbiont of host immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052074</classIRI>
<classLabel>positive regulation by symbiont of host salicylic acid-mediated defense response</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host salicylic acid-mediated defense response&apos; SubClassOf &apos;positive regulation by symbiont of host defense response&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation by symbiont of host salicylic acid-mediated defense response&apos; SubClassOf &apos;induction by symbiont of host defense response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003097</classIRI>
<classLabel>renal water transport</classLabel>
<newAxiom>&apos;renal water transport&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Vertebrata vertebrates&apos;</newAxiom>
<newAxiom>&apos;renal water transport&apos; SubClassOf &apos;in taxon&apos; only &apos;Vertebrata vertebrates&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003096</classIRI>
<classLabel>renal sodium ion transport</classLabel>
<newAxiom>&apos;renal sodium ion transport&apos; SubClassOf &apos;in taxon&apos; only &apos;Vertebrata vertebrates&apos;</newAxiom>
<newAxiom>&apos;renal sodium ion transport&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Vertebrata vertebrates&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003092</classIRI>
<classLabel>renal water retention</classLabel>
<newAxiom>&apos;renal water retention&apos; SubClassOf &apos;in taxon&apos; only &apos;Vertebrata vertebrates&apos;</newAxiom>
<newAxiom>&apos;renal water retention&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Vertebrata vertebrates&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003091</classIRI>
<classLabel>renal water homeostasis</classLabel>
<newAxiom>&apos;renal water homeostasis&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Vertebrata vertebrates&apos;</newAxiom>
<newAxiom>&apos;renal water homeostasis&apos; SubClassOf &apos;in taxon&apos; only &apos;Vertebrata vertebrates&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003050</classIRI>
<classLabel>regulation of systemic arterial blood pressure by atrial natriuretic peptide</classLabel>
<deletedAxiom>&apos;regulation of systemic arterial blood pressure by atrial natriuretic peptide&apos; EquivalentTo &apos;regulation of blood pressure&apos; and (&apos;mediated_by&apos; some &apos;atrial natriuretic factor&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of systemic arterial blood pressure by atrial natriuretic peptide&apos; SubClassOf &apos;mediated_by&apos; some &apos;atrial natriuretic factor&apos;</deletedAxiom>
<newAxiom>&apos;regulation of systemic arterial blood pressure by atrial natriuretic peptide&apos; EquivalentTo &apos;regulation of blood pressure&apos; and (&apos;has causal agent&apos; some &apos;atrial natriuretic factor&apos;)</newAxiom>
<newAxiom>&apos;regulation of systemic arterial blood pressure by atrial natriuretic peptide&apos; SubClassOf &apos;has causal agent&apos; some &apos;atrial natriuretic factor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902496</classIRI>
<classLabel>protein binding involved in negative regulation of telomere maintenance via telomerase</classLabel>
<deletedAxiom>&apos;protein binding involved in negative regulation of telomere maintenance via telomerase&apos; SubClassOf &apos;part of&apos; some &apos;negative regulation of telomere maintenance via telomerase&apos;</deletedAxiom>
<deletedAxiom>&apos;protein binding involved in negative regulation of telomere maintenance via telomerase&apos; EquivalentTo &apos;protein binding&apos; and (&apos;part of&apos; some &apos;negative regulation of telomere maintenance via telomerase&apos;)</deletedAxiom>
<deletedAxiom>&apos;protein binding involved in negative regulation of telomere maintenance via telomerase&apos; SubClassOf &apos;protein binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001310</classIRI>
<classLabel>gliotoxin biosynthetic process</classLabel>
<deletedAxiom>&apos;gliotoxin biosynthetic process&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some &apos;gliotoxin&apos;)</deletedAxiom>
<newAxiom>&apos;gliotoxin biosynthetic process&apos; SubClassOf &apos;has_part&apos; some &apos;transaminase activity&apos;</newAxiom>
<newAxiom>&apos;gliotoxin biosynthetic process&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;gliotoxin biosynthetic process&apos; SubClassOf &apos;has primary input&apos; some &apos;phenylalanine&apos;</newAxiom>
<newAxiom>&apos;gliotoxin biosynthetic process&apos; SubClassOf &apos;has_part&apos; some &apos;N-methyltransferase activity&apos;</newAxiom>
<newAxiom>&apos;gliotoxin biosynthetic process&apos; SubClassOf &apos;has_part&apos; some &apos;gamma-glutamylcyclotransferase activity&apos;</newAxiom>
<newAxiom>&apos;gliotoxin biosynthetic process&apos; SubClassOf &apos;ends with&apos; some &apos;disulfide oxidoreductase activity&apos;</newAxiom>
<newAxiom>&apos;gliotoxin biosynthetic process&apos; SubClassOf &apos;has_part&apos; some &apos;monooxygenase activity&apos;</newAxiom>
<newAxiom>&apos;gliotoxin biosynthetic process&apos; SubClassOf &apos;starts with&apos; some &apos;acid-amino acid ligase activity&apos;</newAxiom>
<newAxiom>&apos;gliotoxin biosynthetic process&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has_part&apos; some &apos;gamma-glutamylcyclotransferase activity&apos;) and (&apos;has_part&apos; some &apos;glutathione transferase activity&apos;) and (&apos;has_part&apos; some &apos;monooxygenase activity&apos;) and (&apos;has_part&apos; some &apos;N-methyltransferase activity&apos;) and (&apos;has_part&apos; some &apos;transaminase activity&apos;) and (&apos;has_part&apos; some &apos;oxidoreductase activity&apos;) and (&apos;starts with&apos; some &apos;acid-amino acid ligase activity&apos;) and (&apos;ends with&apos; some &apos;disulfide oxidoreductase activity&apos;) and (&apos;has primary output&apos; some &apos;gliotoxin&apos;) and (&apos;has primary input&apos; some &apos;serine&apos;) and (&apos;has primary input&apos; some &apos;phenylalanine&apos;)</newAxiom>
<newAxiom>&apos;gliotoxin biosynthetic process&apos; SubClassOf &apos;has primary input&apos; some &apos;serine&apos;</newAxiom>
<newAxiom>&apos;gliotoxin biosynthetic process&apos; SubClassOf &apos;has_part&apos; some &apos;glutathione transferase activity&apos;</newAxiom>
<newAxiom>&apos;gliotoxin biosynthetic process&apos; SubClassOf &apos;aromatic amino acid family metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052004</classIRI>
<classLabel>negative regulation by symbiont of host salicylic acid-mediated defense response</classLabel>
<deletedAxiom>&apos;negative regulation by symbiont of host salicylic acid-mediated defense response&apos; SubClassOf &apos;modulation by symbiont of host salicylic acid-mediated defense response&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation by symbiont of host salicylic acid-mediated defense response&apos; SubClassOf &apos;negatively regulates&apos; some &apos;systemic acquired resistance, salicylic acid mediated signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation by symbiont of host salicylic acid-mediated defense response&apos; SubClassOf &apos;negative regulation of systemic acquired resistance&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation by symbiont of host salicylic acid-mediated defense response&apos; SubClassOf &apos;negative regulation by symbiont of host defense response&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation by symbiont of host salicylic acid-mediated defense response&apos; SubClassOf &apos;negative regulation of cellular response to drug&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation by symbiont of host salicylic acid-mediated defense response&apos; SubClassOf &apos;negative regulation of signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052003</classIRI>
<classLabel>negative regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway</classLabel>
<deletedAxiom>&apos;negative regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway&apos; SubClassOf &apos;negative regulation by symbiont of host salicylic acid-mediated defense response&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway&apos; SubClassOf &apos;negatively regulates&apos; some &apos;systemic acquired resistance, salicylic acid mediated signaling pathway&apos;</newAxiom>
<newAxiom>&apos;negative regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway&apos; SubClassOf &apos;negative regulation of signal transduction&apos;</newAxiom>
<newAxiom>&apos;negative regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway&apos; SubClassOf &apos;modulation by symbiont of host salicylic acid-mediated defense response&apos;</newAxiom>
<newAxiom>&apos;negative regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway&apos; SubClassOf &apos;negative regulation of systemic acquired resistance&apos;</newAxiom>
<newAxiom>&apos;negative regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway&apos; SubClassOf &apos;negative regulation of cellular response to drug&apos;</newAxiom>
<newAxiom>&apos;negative regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway&apos; SubClassOf &apos;suppression of host defenses&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052005</classIRI>
<classLabel>negative regulation by symbiont of host ethylene-mediated defense response</classLabel>
<deletedAxiom>&apos;negative regulation by symbiont of host ethylene-mediated defense response&apos; SubClassOf &apos;negative regulation by symbiont of host defense response&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation by symbiont of host ethylene-mediated defense response&apos; SubClassOf &apos;suppression of host defenses&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052000</classIRI>
<classLabel>type IV pili-dependent aggregation</classLabel>
<newAxiom>&apos;type IV pili-dependent aggregation&apos; SubClassOf &apos;in taxon&apos; only &apos;Prokaryota&apos;</newAxiom>
<newAxiom>&apos;type IV pili-dependent aggregation&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Prokaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052059</classIRI>
<classLabel>evasion or tolerance by symbiont of host-produced reactive oxygen species</classLabel>
<deletedAxiom>&apos;evasion or tolerance by symbiont of host-produced reactive oxygen species&apos; SubClassOf &apos;evasion or tolerance of host immune response&apos;</deletedAxiom>
<deletedAxiom>&apos;evasion or tolerance by symbiont of host-produced reactive oxygen species&apos; SubClassOf &apos;response to defense-related host reactive oxygen species production&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052060</classIRI>
<classLabel>evasion or tolerance by symbiont of host-produced nitric oxide</classLabel>
<deletedAxiom>&apos;evasion or tolerance by symbiont of host-produced nitric oxide&apos; SubClassOf &apos;evasion or tolerance of host immune response&apos;</deletedAxiom>
<deletedAxiom>&apos;evasion or tolerance by symbiont of host-produced nitric oxide&apos; SubClassOf &apos;response to defense-related host nitric oxide production&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052068</classIRI>
<classLabel>negative regulation by symbiont of host jasmonic acid-mediated defense response</classLabel>
<deletedAxiom>&apos;negative regulation by symbiont of host jasmonic acid-mediated defense response&apos; SubClassOf &apos;negative regulation by symbiont of host defense response&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation by symbiont of host jasmonic acid-mediated defense response&apos; SubClassOf &apos;suppression of host defenses&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052061</classIRI>
<classLabel>evasion or tolerance by symbiont of host-produced phytoalexins</classLabel>
<deletedAxiom>&apos;evasion or tolerance by symbiont of host-produced phytoalexins&apos; SubClassOf &apos;evasion or tolerance of host immune response&apos;</deletedAxiom>
<deletedAxiom>&apos;evasion or tolerance by symbiont of host-produced phytoalexins&apos; SubClassOf &apos;response to host phytoalexin production&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052064</classIRI>
<classLabel>induction by symbiont of defense-related host reactive oxygen species production</classLabel>
<deletedAxiom>&apos;induction by symbiont of defense-related host reactive oxygen species production&apos; SubClassOf &apos;positive regulation by symbiont of defense-related host reactive oxygen species production&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052063</classIRI>
<classLabel>induction by symbiont of defense-related host nitric oxide production</classLabel>
<deletedAxiom>&apos;induction by symbiont of defense-related host nitric oxide production&apos; SubClassOf &apos;positive regulation by symbiont of defense-related host nitric oxide production&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052029</classIRI>
<classLabel>negative regulation by symbiont of host signal transduction pathway</classLabel>
<deletedAxiom>&apos;negative regulation by symbiont of host signal transduction pathway&apos; SubClassOf &apos;negative regulation by organism of signal transduction in other organism involved in symbiotic interaction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052028</classIRI>
<classLabel>positive regulation by symbiont of host signal transduction pathway</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host signal transduction pathway&apos; SubClassOf &apos;positive regulation by organism of signal transduction in other organism involved in symbiotic interaction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052027</classIRI>
<classLabel>modulation by symbiont of host signal transduction pathway</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host signal transduction pathway&apos; SubClassOf &apos;modulation of signal transduction in other organism involved in symbiotic interaction&apos;</deletedAxiom>
<newAxiom>&apos;modulation by symbiont of host signal transduction pathway&apos; SubClassOf &apos;modulation of signal transduction in other organism&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052035</classIRI>
<classLabel>positive regulation by symbiont of host inflammatory response</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host inflammatory response&apos; SubClassOf &apos;positive regulation by symbiont of host defense response&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation by symbiont of host inflammatory response&apos; SubClassOf &apos;induction by symbiont of host defense response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052037</classIRI>
<classLabel>negative regulation by symbiont of host defense response</classLabel>
<deletedAxiom>&apos;negative regulation by symbiont of host defense response&apos; SubClassOf &apos;suppression of host defenses&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation by symbiont of host defense response&apos; SubClassOf &apos;suppression of defense response of other organism involved in symbiotic interaction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052036</classIRI>
<classLabel>negative regulation by symbiont of host inflammatory response</classLabel>
<deletedAxiom>&apos;negative regulation by symbiont of host inflammatory response&apos; SubClassOf &apos;negative regulation by symbiont of host defense response&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation by symbiont of host inflammatory response&apos; SubClassOf &apos;suppression of host defenses&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902768</classIRI>
<classLabel>isoprenoid biosynthetic process via 1-deoxy-D-xylulose 5-phosphate</classLabel>
<deletedAxiom>&apos;isoprenoid biosynthetic process via 1-deoxy-D-xylulose 5-phosphate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;1-deoxy-D-xylulose 5-phosphate&apos;) and (&apos;has primary output&apos; some &apos;isoprenoid&apos;)</deletedAxiom>
<deletedAxiom>&apos;isoprenoid biosynthetic process via 1-deoxy-D-xylulose 5-phosphate&apos; SubClassOf &apos;has intermediate&apos; some &apos;1-deoxy-D-xylulose 5-phosphate&apos;</deletedAxiom>
<newAxiom>&apos;isoprenoid biosynthetic process via 1-deoxy-D-xylulose 5-phosphate&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;1-deoxy-D-xylulose 5-phosphate&apos;) and (&apos;has primary output&apos; some &apos;isoprenoid&apos;)</newAxiom>
<newAxiom>&apos;isoprenoid biosynthetic process via 1-deoxy-D-xylulose 5-phosphate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;1-deoxy-D-xylulose 5-phosphate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902767</classIRI>
<classLabel>isoprenoid biosynthetic process via mevalonate</classLabel>
<deletedAxiom>&apos;isoprenoid biosynthetic process via mevalonate&apos; SubClassOf &apos;has intermediate&apos; some &apos;mevalonate&apos;</deletedAxiom>
<deletedAxiom>&apos;isoprenoid biosynthetic process via mevalonate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;mevalonate&apos;) and (&apos;has primary output&apos; some &apos;isoprenoid&apos;)</deletedAxiom>
<newAxiom>&apos;isoprenoid biosynthetic process via mevalonate&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;mevalonate&apos;) and (&apos;has primary output&apos; some &apos;isoprenoid&apos;)</newAxiom>
<newAxiom>&apos;isoprenoid biosynthetic process via mevalonate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;mevalonate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042450</classIRI>
<classLabel>arginine biosynthetic process via ornithine</classLabel>
<deletedAxiom>&apos;arginine biosynthetic process via ornithine&apos; SubClassOf &apos;has intermediate&apos; some &apos;ornithinate&apos;</deletedAxiom>
<deletedAxiom>&apos;arginine biosynthetic process via ornithine&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has intermediate&apos; some &apos;ornithinate&apos;) and (&apos;has primary output&apos; some &apos;argininate&apos;)</deletedAxiom>
<newAxiom>&apos;arginine biosynthetic process via ornithine&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002505 some &apos;ornithinate&apos;</newAxiom>
<newAxiom>&apos;arginine biosynthetic process via ornithine&apos; EquivalentTo &apos;biosynthetic process&apos; and (http://purl.obolibrary.org/obo/RO_0002505 some &apos;ornithinate&apos;) and (&apos;has primary output&apos; some &apos;argininate&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042392</classIRI>
<classLabel>sphingosine-1-phosphate phosphatase activity</classLabel>
<deletedAxiom>&apos;sphingosine-1-phosphate phosphatase activity&apos; SubClassOf &apos;phosphatase activity&apos;</deletedAxiom>
<newAxiom>&apos;sphingosine-1-phosphate phosphatase activity&apos; SubClassOf &apos;lipid phosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042302</classIRI>
<classLabel>structural constituent of cuticle</classLabel>
<newAxiom>&apos;structural constituent of cuticle&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eumetazoa&apos;</newAxiom>
<newAxiom>&apos;structural constituent of cuticle&apos; SubClassOf &apos;in taxon&apos; only &apos;Eumetazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042267</classIRI>
<classLabel>natural killer cell mediated cytotoxicity</classLabel>
<deletedAxiom>&apos;natural killer cell mediated cytotoxicity&apos; EquivalentTo &apos;cell killing&apos; and (&apos;mediated_by&apos; some &apos;natural killer cell&apos;)</deletedAxiom>
<newAxiom>&apos;natural killer cell mediated cytotoxicity&apos; EquivalentTo &apos;cell killing&apos; and (&apos;has causal agent&apos; some &apos;natural killer cell&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042147</classIRI>
<classLabel>retrograde transport, endosome to Golgi</classLabel>
<deletedAxiom>&apos;retrograde transport, endosome to Golgi&apos; EquivalentTo &apos;transport&apos; and (&apos;occurs in&apos; some &apos;cytosol&apos;) and (&apos;mediated_by&apos; some &apos;vesicle&apos;) and (&apos;has target start location&apos; some &apos;endosome&apos;) and (&apos;has target end location&apos; some &apos;Golgi apparatus&apos;)</deletedAxiom>
<newAxiom>&apos;retrograde transport, endosome to Golgi&apos; EquivalentTo &apos;transport&apos; and (&apos;occurs in&apos; some &apos;cytosol&apos;) and (&apos;has target start location&apos; some &apos;endosome&apos;) and (&apos;has target end location&apos; some &apos;Golgi apparatus&apos;) and (&apos;has causal agent&apos; some &apos;vesicle&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042073</classIRI>
<classLabel>intraciliary transport</classLabel>
<newAxiom>&apos;intraciliary transport&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Dictyostelium&apos;))</newAxiom>
<newAxiom>&apos;intraciliary transport&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Gnetales&apos;))</newAxiom>
<newAxiom>&apos;intraciliary transport&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Ascomycota&apos;))</newAxiom>
<newAxiom>&apos;intraciliary transport&apos; DisjointWith &apos;in taxon&apos; some &apos;Dictyostelium&apos;</newAxiom>
<newAxiom>&apos;intraciliary transport&apos; DisjointWith &apos;in taxon&apos; some &apos;Ascomycota&apos;</newAxiom>
<newAxiom>&apos;intraciliary transport&apos; DisjointWith &apos;in taxon&apos; some &apos;Gnetales&apos;</newAxiom>
<newAxiom>&apos;intraciliary transport&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;intraciliary transport&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Zygnematales&apos;))</newAxiom>
<newAxiom>&apos;intraciliary transport&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Magnoliopsida&apos;))</newAxiom>
<newAxiom>&apos;intraciliary transport&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;intraciliary transport&apos; DisjointWith &apos;in taxon&apos; some &apos;Magnoliopsida&apos;</newAxiom>
<newAxiom>&apos;intraciliary transport&apos; DisjointWith &apos;in taxon&apos; some &apos;Coniferophyta&apos;</newAxiom>
<newAxiom>&apos;intraciliary transport&apos; DisjointWith &apos;in taxon&apos; some &apos;Zygnematales&apos;</newAxiom>
<newAxiom>&apos;intraciliary transport&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Coniferophyta&apos;))</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007610</classIRI>
<classLabel>behavior</classLabel>
<deletedAxiom>&apos;behavior&apos; SubClassOf &apos;mediated_by&apos; some &apos;nervous system&apos;</deletedAxiom>
<newAxiom>&apos;behavior&apos; SubClassOf &apos;has causal agent&apos; some &apos;nervous system&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032507</classIRI>
<classLabel>maintenance of protein location in cell</classLabel>
<newAxiom>&apos;maintenance of protein location in cell&apos; SubClassOf &apos;in taxon&apos; only &apos;cellular organisms&apos;</newAxiom>
<newAxiom>&apos;maintenance of protein location in cell&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;cellular organisms&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032543</classIRI>
<classLabel>mitochondrial translation</classLabel>
<newAxiom>&apos;mitochondrial translation&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;mitochondrial translation&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032544</classIRI>
<classLabel>plastid translation</classLabel>
<newAxiom>&apos;plastid translation&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Metazoa&apos;))</newAxiom>
<newAxiom>&apos;plastid translation&apos; DisjointWith &apos;in taxon&apos; some &apos;Bacteria&apos;</newAxiom>
<newAxiom>&apos;plastid translation&apos; DisjointWith &apos;in taxon&apos; some &apos;Archaea&apos;</newAxiom>
<newAxiom>&apos;plastid translation&apos; DisjointWith &apos;in taxon&apos; some &apos;Fungi&apos;</newAxiom>
<newAxiom>&apos;plastid translation&apos; DisjointWith &apos;in taxon&apos; some &apos;Amoebozoa&apos;</newAxiom>
<newAxiom>&apos;plastid translation&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Choanoflagellata&apos;))</newAxiom>
<newAxiom>&apos;plastid translation&apos; DisjointWith &apos;in taxon&apos; some &apos;Choanoflagellata&apos;</newAxiom>
<newAxiom>&apos;plastid translation&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Amoebozoa&apos;))</newAxiom>
<newAxiom>&apos;plastid translation&apos; DisjointWith &apos;in taxon&apos; some &apos;Metazoa&apos;</newAxiom>
<newAxiom>&apos;plastid translation&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Bacteria&apos;))</newAxiom>
<newAxiom>&apos;plastid translation&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Archaea&apos;))</newAxiom>
<newAxiom>&apos;plastid translation&apos; SubClassOf &apos;in taxon&apos; only (not (&apos;Fungi&apos;))</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032468</classIRI>
<classLabel>Golgi calcium ion homeostasis</classLabel>
<newAxiom>&apos;Golgi calcium ion homeostasis&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;Golgi calcium ion homeostasis&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032469</classIRI>
<classLabel>endoplasmic reticulum calcium ion homeostasis</classLabel>
<newAxiom>&apos;endoplasmic reticulum calcium ion homeostasis&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eukaryota&apos;</newAxiom>
<newAxiom>&apos;endoplasmic reticulum calcium ion homeostasis&apos; SubClassOf &apos;in taxon&apos; only &apos;Eukaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140246</classIRI>
<classLabel>protein catabolic process at synapse</classLabel>
<newAxiom>&apos;protein catabolic process at synapse&apos; SubClassOf &apos;in taxon&apos; only &apos;Metazoa&apos;</newAxiom>
<newAxiom>&apos;protein catabolic process at synapse&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Metazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140250</classIRI>
<classLabel>regulation protein catabolic process at synapse</classLabel>
<newAxiom>&apos;regulation protein catabolic process at synapse&apos; SubClassOf &apos;in taxon&apos; only &apos;Metazoa&apos;</newAxiom>
<newAxiom>&apos;regulation protein catabolic process at synapse&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Metazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140243</classIRI>
<classLabel>regulation of translation at synapse</classLabel>
<newAxiom>&apos;regulation of translation at synapse&apos; SubClassOf &apos;in taxon&apos; only &apos;Metazoa&apos;</newAxiom>
<newAxiom>&apos;regulation of translation at synapse&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Metazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140241</classIRI>
<classLabel>translation at synapse</classLabel>
<newAxiom>&apos;translation at synapse&apos; SubClassOf &apos;in taxon&apos; only &apos;Metazoa&apos;</newAxiom>
<newAxiom>&apos;translation at synapse&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Metazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071955</classIRI>
<classLabel>recycling endosome to Golgi transport</classLabel>
<deletedAxiom>&apos;recycling endosome to Golgi transport&apos; EquivalentTo &apos;transport&apos; and (&apos;mediated_by&apos; some &apos;vesicle&apos;) and (&apos;has target start location&apos; some &apos;recycling endosome&apos;) and (&apos;has target end location&apos; some &apos;Golgi apparatus&apos;)</deletedAxiom>
<newAxiom>&apos;recycling endosome to Golgi transport&apos; EquivalentTo &apos;transport&apos; and (&apos;has target start location&apos; some &apos;recycling endosome&apos;) and (&apos;has target end location&apos; some &apos;Golgi apparatus&apos;) and (&apos;has causal agent&apos; some &apos;vesicle&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071934</classIRI>
<classLabel>thiamine transmembrane transport</classLabel>
<newAxiom>&apos;thiamine transmembrane transport&apos; SubClassOf &apos;azole transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071990</classIRI>
<classLabel>maintenance of protein location to spindle pole body</classLabel>
<newAxiom>&apos;maintenance of protein location to spindle pole body&apos; SubClassOf &apos;in taxon&apos; only &apos;Fungi&apos;</newAxiom>
<newAxiom>&apos;maintenance of protein location to spindle pole body&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Fungi&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007306</classIRI>
<classLabel>eggshell chorion assembly</classLabel>
<deletedAxiom>&apos;eggshell chorion assembly&apos; SubClassOf &apos;results in assembly of&apos; some &apos;egg chorion&apos;</deletedAxiom>
<deletedAxiom>&apos;eggshell chorion assembly&apos; EquivalentTo &apos;cellular process&apos; and (&apos;results in assembly of&apos; some &apos;egg chorion&apos;)</deletedAxiom>
<newAxiom>&apos;eggshell chorion assembly&apos; SubClassOf &apos;external encapsulating structure organization&apos;</newAxiom>
<newAxiom>&apos;eggshell chorion assembly&apos; EquivalentTo &apos;cellular process&apos; and (&apos;results in assembly of&apos; some &apos;chorion&apos;)</newAxiom>
<newAxiom>&apos;eggshell chorion assembly&apos; SubClassOf &apos;results in assembly of&apos; some &apos;chorion&apos;</newAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_7198</classIRI>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_7393</classIRI>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/IAO_0000409</classIRI>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/IAO_0000225</classIRI>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_6182</classIRI>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_6185</classIRI>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_6183</classIRI>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/IAO_0000078</classIRI>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/IDO_0000403</classIRI>
</newClass>
<newClass>
<classIRI>http://www.geneontology.org/formats/oboInOwl#Subset</classIRI>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_5833</classIRI>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120219</classIRI>
<classLabel>subapical part of cell</classLabel>
<newAxiom>'subapical part of cell' SubClassOf 'cellular anatomical entity'</newAxiom>
<newAxiom>'subapical part of cell' SubClassOf 'part of' some 'cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120220</classIRI>
<classLabel>basal body patch</classLabel>
<newAxiom>'basal body patch' SubClassOf 'cellular anatomical entity'</newAxiom>
<newAxiom>'basal body patch' SubClassOf 'part of' some 'apical part of cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_5664</classIRI>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_5693</classIRI>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_5691</classIRI>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_70999</classIRI>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000056</classIRI>
<classLabel>Trypanosoma brucei metacyclic trypomastigote stage</classLabel>
<newAxiom>'Trypanosoma brucei metacyclic trypomastigote stage' SubClassOf 'occurs in' some 'Glossina salivary gland'</newAxiom>
<newAxiom>'Trypanosoma brucei metacyclic trypomastigote stage' SubClassOf 'Trypanosoma brucei trypomastigote stage'</newAxiom>
<newAxiom>'Trypanosoma brucei metacyclic trypomastigote stage' SubClassOf 'metacyclic trypomastigote stage'</newAxiom>
<newAxiom>'Trypanosoma brucei metacyclic trypomastigote stage' EquivalentTo 'metacyclic trypomastigote stage' and ('has_participant' only http://purl.obolibrary.org/obo/NCBITaxon_5691)</newAxiom>
<newAxiom>'Trypanosoma brucei metacyclic trypomastigote stage' SubClassOf 'occurs in' some 'Mammalia blood'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000048</classIRI>
<classLabel>Trypanosoma brucei lifecycle stage</classLabel>
<newAxiom>'Trypanosoma brucei lifecycle stage' EquivalentTo 'parasite lifecycle stage' and ('has_participant' only http://purl.obolibrary.org/obo/NCBITaxon_5691)</newAxiom>
<newAxiom>'Trypanosoma brucei lifecycle stage' SubClassOf 'parasite lifecycle stage'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000088</classIRI>
<classLabel>Triatominae midgut</classLabel>
<newAxiom>'Triatominae midgut' SubClassOf 'midgut'</newAxiom>
<newAxiom>'Triatominae midgut' EquivalentTo 'midgut' and ('part of' some http://purl.obolibrary.org/obo/NCBITaxon_70999)</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000015</classIRI>
<classLabel>Phlebotominae proboscis</classLabel>
<newAxiom>'Phlebotominae proboscis' SubClassOf http://purl.obolibrary.org/obo/BTO_0001117</newAxiom>
<newAxiom>'Phlebotominae proboscis' EquivalentTo http://purl.obolibrary.org/obo/BTO_0001117 and ('part of' some http://purl.obolibrary.org/obo/NCBITaxon_7198)</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000033</classIRI>
<classLabel>trypomastigote stage</classLabel>
<newAxiom>'trypomastigote stage' SubClassOf 'parasite lifecycle stage'</newAxiom>
<newAxiom>'trypomastigote stage' SubClassOf 'has_participant' only 'parasite organism'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000004</classIRI>
<classLabel>Triatominae hindgut</classLabel>
<newAxiom>'Triatominae hindgut' EquivalentTo 'hindgut' and ('part of' some http://purl.obolibrary.org/obo/NCBITaxon_70999)</newAxiom>
<newAxiom>'Triatominae hindgut' SubClassOf 'hindgut'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000006</classIRI>
<classLabel>metacyclic promastigote stage</classLabel>
<newAxiom>'metacyclic promastigote stage' SubClassOf 'promastigote stage'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000310</classIRI>
<classLabel>Vertebrate blood</classLabel>
<newAxiom>'Vertebrate blood' EquivalentTo 'blood' and ('part of' some 'Vertebrata vertebrates')</newAxiom>
<newAxiom>'Vertebrate blood' SubClassOf 'blood'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000321</classIRI>
<classLabel>Mammalia macrophage</classLabel>
<newAxiom>'Mammalia macrophage' EquivalentTo 'macrophage' and ('part of' some 'Mammalia')</newAxiom>
<newAxiom>'Mammalia macrophage' SubClassOf 'macrophage'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000320</classIRI>
<classLabel>Mammalia blood</classLabel>
<newAxiom>'Mammalia blood' EquivalentTo 'blood' and ('part of' some 'Mammalia')</newAxiom>
<newAxiom>'Mammalia blood' SubClassOf 'Vertebrate blood'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000313</classIRI>
<classLabel>Mammalia cerebrospinal fluid</classLabel>
<newAxiom>'Mammalia cerebrospinal fluid' SubClassOf 'cerebrospinal fluid'</newAxiom>
<newAxiom>'Mammalia cerebrospinal fluid' EquivalentTo 'cerebrospinal fluid' and ('part of' some 'Mammalia')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000185</classIRI>
<classLabel>Trypanosoma cruzi lifecycle stage</classLabel>
<newAxiom>'Trypanosoma cruzi lifecycle stage' SubClassOf 'parasite lifecycle stage'</newAxiom>
<newAxiom>'Trypanosoma cruzi lifecycle stage' EquivalentTo 'parasite lifecycle stage' and ('has_participant' only http://purl.obolibrary.org/obo/NCBITaxon_5693)</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000189</classIRI>
<classLabel>Leishmania major promastigote stage</classLabel>
<newAxiom>'Leishmania major promastigote stage' SubClassOf 'promastigote stage'</newAxiom>
<newAxiom>'Leishmania major promastigote stage' SubClassOf 'occurs in' some 'Phlebotominae proboscis'</newAxiom>
<newAxiom>'Leishmania major promastigote stage' SubClassOf 'occurs in' some 'Mammalia macrophage'</newAxiom>
<newAxiom>'Leishmania major promastigote stage' EquivalentTo 'promastigote stage' and ('has_participant' only http://purl.obolibrary.org/obo/NCBITaxon_5664)</newAxiom>
<newAxiom>'Leishmania major promastigote stage' SubClassOf 'Leishmania major lifecycle stage'</newAxiom>
<newAxiom>'Leishmania major promastigote stage' SubClassOf 'occurs in' some 'Phlebotominae midgut'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000181</classIRI>
<classLabel>parasite lifecycle stage</classLabel>
<newAxiom>'parasite lifecycle stage' EquivalentTo 'life cycle stage' and ('has_participant' only 'parasite organism')</newAxiom>
<newAxiom>'parasite lifecycle stage' SubClassOf 'life cycle stage'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000194</classIRI>
<classLabel>Phlebotominae midgut</classLabel>
<newAxiom>'Phlebotominae midgut' SubClassOf 'midgut'</newAxiom>
<newAxiom>'Phlebotominae midgut' EquivalentTo 'midgut' and ('part of' some http://purl.obolibrary.org/obo/NCBITaxon_7198)</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000165</classIRI>
<classLabel>Plasmodium falciparum lifecycle stage</classLabel>
<newAxiom>'Plasmodium falciparum lifecycle stage' EquivalentTo 'parasite lifecycle stage' and ('has_participant' only http://purl.obolibrary.org/obo/NCBITaxon_5833)</newAxiom>
<newAxiom>'Plasmodium falciparum lifecycle stage' SubClassOf 'parasite lifecycle stage'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000175</classIRI>
<classLabel>Trypanosoma brucei trypomastigote stage</classLabel>
<newAxiom>'Trypanosoma brucei trypomastigote stage' SubClassOf 'occurs in' some 'Mammalia cerebrospinal fluid'</newAxiom>
<newAxiom>'Trypanosoma brucei trypomastigote stage' SubClassOf 'occurs in' some 'Mammalia blood'</newAxiom>
<newAxiom>'Trypanosoma brucei trypomastigote stage' SubClassOf 'trypomastigote stage'</newAxiom>
<newAxiom>'Trypanosoma brucei trypomastigote stage' SubClassOf 'Trypanosoma brucei lifecycle stage'</newAxiom>
<newAxiom>'Trypanosoma brucei trypomastigote stage' EquivalentTo 'trypomastigote stage' and ('has_participant' only http://purl.obolibrary.org/obo/NCBITaxon_5691)</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000177</classIRI>
<classLabel>Schistosoma haematobium lifecycle stage</classLabel>
<newAxiom>'Schistosoma haematobium lifecycle stage' EquivalentTo 'parasite lifecycle stage' and ('has_participant' only http://purl.obolibrary.org/obo/NCBITaxon_6185)</newAxiom>
<newAxiom>'Schistosoma haematobium lifecycle stage' SubClassOf 'parasite lifecycle stage'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000169</classIRI>
<classLabel>Trypanosoma cruzi trypomastigote stage</classLabel>
<newAxiom>'Trypanosoma cruzi trypomastigote stage' SubClassOf 'occurs in' some 'Mammalia macrophage'</newAxiom>
<newAxiom>'Trypanosoma cruzi trypomastigote stage' SubClassOf 'trypomastigote stage'</newAxiom>
<newAxiom>'Trypanosoma cruzi trypomastigote stage' SubClassOf 'occurs in' some 'Mammalia blood'</newAxiom>
<newAxiom>'Trypanosoma cruzi trypomastigote stage' SubClassOf 'occurs in' some 'Triatominae hindgut'</newAxiom>
<newAxiom>'Trypanosoma cruzi trypomastigote stage' EquivalentTo 'trypomastigote stage' and ('has_participant' only http://purl.obolibrary.org/obo/NCBITaxon_5693)</newAxiom>
<newAxiom>'Trypanosoma cruzi trypomastigote stage' SubClassOf 'Trypanosoma cruzi lifecycle stage'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000102</classIRI>
<classLabel>Leishmania major metacyclic promastigote stage</classLabel>
<newAxiom>'Leishmania major metacyclic promastigote stage' SubClassOf 'occurs in' some 'Phlebotominae proboscis'</newAxiom>
<newAxiom>'Leishmania major metacyclic promastigote stage' EquivalentTo 'metacyclic promastigote stage' and ('has_participant' only http://purl.obolibrary.org/obo/NCBITaxon_5664)</newAxiom>
<newAxiom>'Leishmania major metacyclic promastigote stage' SubClassOf 'occurs in' some 'Mammalia macrophage'</newAxiom>
<newAxiom>'Leishmania major metacyclic promastigote stage' SubClassOf 'metacyclic promastigote stage'</newAxiom>
<newAxiom>'Leishmania major metacyclic promastigote stage' SubClassOf 'Leishmania major promastigote stage'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000151</classIRI>
<classLabel>promastigote stage</classLabel>
<newAxiom>'promastigote stage' SubClassOf 'has_participant' only 'parasite organism'</newAxiom>
<newAxiom>'promastigote stage' SubClassOf 'parasite lifecycle stage'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000154</classIRI>
<classLabel>Glossina salivary gland</classLabel>
<newAxiom>'Glossina salivary gland' EquivalentTo 'saliva-secreting gland' and ('part of' some http://purl.obolibrary.org/obo/NCBITaxon_7393)</newAxiom>
<newAxiom>'Glossina salivary gland' SubClassOf 'saliva-secreting gland'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000156</classIRI>
<classLabel>Schistosoma japonicum lifecycle stage</classLabel>
<newAxiom>'Schistosoma japonicum lifecycle stage' EquivalentTo 'parasite lifecycle stage' and ('has_participant' only http://purl.obolibrary.org/obo/NCBITaxon_6182)</newAxiom>
<newAxiom>'Schistosoma japonicum lifecycle stage' SubClassOf 'parasite lifecycle stage'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000149</classIRI>
<classLabel>metacyclic trypomastigote stage</classLabel>
<newAxiom>'metacyclic trypomastigote stage' SubClassOf 'trypomastigote stage'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000131</classIRI>
<classLabel>Trypanosoma cruzi metacyclic trypomastigote stage</classLabel>
<newAxiom>'Trypanosoma cruzi metacyclic trypomastigote stage' SubClassOf 'metacyclic trypomastigote stage'</newAxiom>
<newAxiom>'Trypanosoma cruzi metacyclic trypomastigote stage' EquivalentTo 'metacyclic trypomastigote stage' and ('has_participant' only http://purl.obolibrary.org/obo/NCBITaxon_5693)</newAxiom>
<newAxiom>'Trypanosoma cruzi metacyclic trypomastigote stage' SubClassOf 'occurs in' some 'Mammalia blood'</newAxiom>
<newAxiom>'Trypanosoma cruzi metacyclic trypomastigote stage' SubClassOf 'occurs in' some 'Mammalia macrophage'</newAxiom>
<newAxiom>'Trypanosoma cruzi metacyclic trypomastigote stage' SubClassOf 'Trypanosoma cruzi trypomastigote stage'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000215</classIRI>
<classLabel>Glossina midgut</classLabel>
<newAxiom>'Glossina midgut' SubClassOf 'midgut'</newAxiom>
<newAxiom>'Glossina midgut' EquivalentTo 'midgut' and ('part of' some http://purl.obolibrary.org/obo/NCBITaxon_7393)</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000232</classIRI>
<classLabel>parasite organism</classLabel>
<newAxiom>'parasite organism' EquivalentTo http://purl.obolibrary.org/obo/OBI_0100026 and ('has role' some http://purl.obolibrary.org/obo/IDO_0000403)</newAxiom>
<newAxiom>'parasite organism' SubClassOf 'independent continuant'</newAxiom>
<newAxiom>'parasite organism' SubClassOf http://purl.obolibrary.org/obo/OBI_0100026</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000209</classIRI>
<classLabel>Leishmania major lifecycle stage</classLabel>
<newAxiom>'Leishmania major lifecycle stage' SubClassOf 'parasite lifecycle stage'</newAxiom>
<newAxiom>'Leishmania major lifecycle stage' EquivalentTo 'parasite lifecycle stage' and ('has_participant' only http://purl.obolibrary.org/obo/NCBITaxon_5664)</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000203</classIRI>
<classLabel>Schistosoma mansoni lifecycle stage</classLabel>
<newAxiom>'Schistosoma mansoni lifecycle stage' SubClassOf 'parasite lifecycle stage'</newAxiom>
<newAxiom>'Schistosoma mansoni lifecycle stage' EquivalentTo 'parasite lifecycle stage' and ('has_participant' only http://purl.obolibrary.org/obo/NCBITaxon_6183)</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106235</classIRI>
<classLabel>ceramide-1-phosphate phosphatase activity</classLabel>
<newAxiom>'ceramide-1-phosphate phosphatase activity' SubClassOf 'lipid phosphatase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106234</classIRI>
<classLabel>outer membrane protein complex</classLabel>
<newAxiom>'outer membrane protein complex' SubClassOf 'membrane protein complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062173</classIRI>
<classLabel>brexanolone metabolic process</classLabel>
<newAxiom>'brexanolone metabolic process' EquivalentTo 'metabolic process' and ('has primary input or output' some 'brexanolone')</newAxiom>
<newAxiom>'brexanolone metabolic process' SubClassOf 'has primary input or output' some 'brexanolone'</newAxiom>
<newAxiom>'brexanolone metabolic process' SubClassOf 'organic hydroxy compound metabolic process'</newAxiom>
<newAxiom>'brexanolone metabolic process' SubClassOf 'steroid metabolic process'</newAxiom>
<newAxiom>'brexanolone metabolic process' SubClassOf 'cellular ketone metabolic process'</newAxiom>
<newAxiom>'brexanolone metabolic process' SubClassOf 'drug metabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062172</classIRI>
<classLabel>lutein catabolic process</classLabel>
<newAxiom>'lutein catabolic process' SubClassOf 'has primary input' some 'lutein'</newAxiom>
<newAxiom>'lutein catabolic process' EquivalentTo 'catabolic process' and ('has primary input' some 'lutein')</newAxiom>
<newAxiom>'lutein catabolic process' SubClassOf 'lutein metabolic process'</newAxiom>
<newAxiom>'lutein catabolic process' SubClassOf 'xanthophyll catabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062171</classIRI>
<classLabel>lutein biosynthetic process</classLabel>
<newAxiom>'lutein biosynthetic process' SubClassOf 'xanthophyll biosynthetic process'</newAxiom>
<newAxiom>'lutein biosynthetic process' SubClassOf 'has primary output' some 'lutein'</newAxiom>
<newAxiom>'lutein biosynthetic process' EquivalentTo 'biosynthetic process' and ('has primary output' some 'lutein')</newAxiom>
<newAxiom>'lutein biosynthetic process' SubClassOf 'lutein metabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062170</classIRI>
<classLabel>lutein metabolic process</classLabel>
<newAxiom>'lutein metabolic process' SubClassOf 'has primary input or output' some 'lutein'</newAxiom>
<newAxiom>'lutein metabolic process' EquivalentTo 'metabolic process' and ('has primary input or output' some 'lutein')</newAxiom>
<newAxiom>'lutein metabolic process' SubClassOf 'xanthophyll metabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062177</classIRI>
<classLabel>radial spoke assembly</classLabel>
<newAxiom>'radial spoke assembly' SubClassOf 'part of' some 'axoneme assembly'</newAxiom>
<newAxiom>'radial spoke assembly' SubClassOf 'protein-containing complex assembly'</newAxiom>
<newAxiom>'radial spoke assembly' EquivalentTo 'cellular process' and ('results in assembly of' some 'radial spoke')</newAxiom>
<newAxiom>'radial spoke assembly' SubClassOf 'results in assembly of' some 'radial spoke'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062176</classIRI>
<classLabel>R-loop disassembly</classLabel>
<newAxiom>'R-loop disassembly' SubClassOf 'part of' some 'DNA-dependent DNA replication'</newAxiom>
<newAxiom>'R-loop disassembly' SubClassOf 'DNA metabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062175</classIRI>
<classLabel>brexanolone catabolic process</classLabel>
<newAxiom>'brexanolone catabolic process' SubClassOf 'steroid catabolic process'</newAxiom>
<newAxiom>'brexanolone catabolic process' SubClassOf 'ketone catabolic process'</newAxiom>
<newAxiom>'brexanolone catabolic process' SubClassOf 'brexanolone metabolic process'</newAxiom>
<newAxiom>'brexanolone catabolic process' EquivalentTo 'catabolic process' and ('has primary input' some 'brexanolone')</newAxiom>
<newAxiom>'brexanolone catabolic process' SubClassOf 'has primary input' some 'brexanolone'</newAxiom>
<newAxiom>'brexanolone catabolic process' SubClassOf 'organic hydroxy compound catabolic process'</newAxiom>
<newAxiom>'brexanolone catabolic process' SubClassOf 'drug catabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062174</classIRI>
<classLabel>brexanolone biosynthetic process</classLabel>
<newAxiom>'brexanolone biosynthetic process' SubClassOf 'brexanolone metabolic process'</newAxiom>
<newAxiom>'brexanolone biosynthetic process' EquivalentTo 'biosynthetic process' and ('has primary output' some 'brexanolone')</newAxiom>
<newAxiom>'brexanolone biosynthetic process' SubClassOf 'has primary output' some 'brexanolone'</newAxiom>
<newAxiom>'brexanolone biosynthetic process' SubClassOf 'steroid biosynthetic process'</newAxiom>
<newAxiom>'brexanolone biosynthetic process' SubClassOf 'ketone biosynthetic process'</newAxiom>
<newAxiom>'brexanolone biosynthetic process' SubClassOf 'organic hydroxy compound biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062169</classIRI>
<classLabel>regulation of plus-end directed microtubule sliding</classLabel>
<newAxiom>'regulation of plus-end directed microtubule sliding' EquivalentTo 'biological_process' and ('regulates' some 'plus-end directed microtubule sliding')</newAxiom>
<newAxiom>'regulation of plus-end directed microtubule sliding' SubClassOf 'regulation of microtubule-based movement'</newAxiom>
<newAxiom>'regulation of plus-end directed microtubule sliding' SubClassOf 'regulates' some 'plus-end directed microtubule sliding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062168</classIRI>
<classLabel>negative regulation of plus-end directed microtubule sliding</classLabel>
<newAxiom>'negative regulation of plus-end directed microtubule sliding' SubClassOf 'negatively regulates' some 'plus-end directed microtubule sliding'</newAxiom>
<newAxiom>'negative regulation of plus-end directed microtubule sliding' SubClassOf 'regulation of plus-end directed microtubule sliding'</newAxiom>
<newAxiom>'negative regulation of plus-end directed microtubule sliding' SubClassOf 'negative regulation of cellular component movement'</newAxiom>
<newAxiom>'negative regulation of plus-end directed microtubule sliding' EquivalentTo 'biological_process' and ('negatively regulates' some 'plus-end directed microtubule sliding')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062167</classIRI>
<classLabel>complement component C1q complex</classLabel>
<newAxiom>'complement component C1q complex' SubClassOf 'part of' some 'extracellular space'</newAxiom>
<newAxiom>'complement component C1q complex' SubClassOf 'protein-containing complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062180</classIRI>
<classLabel>25-hydroxycholecalciferol-23-hydroxylase activity</classLabel>
<newAxiom>'25-hydroxycholecalciferol-23-hydroxylase activity' SubClassOf 'vitamin D 23-hydroxylase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062184</classIRI>
<classLabel>testosterone 16-beta-hydroxylase activity</classLabel>
<newAxiom>'testosterone 16-beta-hydroxylase activity' SubClassOf 'monooxygenase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062183</classIRI>
<classLabel>all-trans retinoic acid 18-hydroxylase activity</classLabel>
<newAxiom>'all-trans retinoic acid 18-hydroxylase activity' SubClassOf 'monooxygenase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062182</classIRI>
<classLabel>all-trans retinoic acid 4-hydrolase activity</classLabel>
<newAxiom>'all-trans retinoic acid 4-hydrolase activity' SubClassOf 'retinoic acid 4-hydroxylase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062181</classIRI>
<classLabel>1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity</classLabel>
<newAxiom>'1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity' SubClassOf 'vitamin D 23-hydroxylase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062188</classIRI>
<classLabel>anandamide 11,12 epoxidase activity</classLabel>
<newAxiom>'anandamide 11,12 epoxidase activity' SubClassOf 'anandamide epoxidase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062187</classIRI>
<classLabel>anandamide 8,9 epoxidase activity</classLabel>
<newAxiom>'anandamide 8,9 epoxidase activity' SubClassOf 'anandamide epoxidase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062186</classIRI>
<classLabel>anandamide epoxidase activity</classLabel>
<newAxiom>'anandamide epoxidase activity' SubClassOf 'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062185</classIRI>
<classLabel>secalciferol 1-monooxygenase activity</classLabel>
<newAxiom>'secalciferol 1-monooxygenase activity' SubClassOf 'monooxygenase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062179</classIRI>
<classLabel>vitamin D 23-hydroxylase activity</classLabel>
<newAxiom>'vitamin D 23-hydroxylase activity' SubClassOf 'monooxygenase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062178</classIRI>
<classLabel>stationary phase</classLabel>
<newAxiom>'stationary phase' SubClassOf 'single-celled organism vegetative growth phase'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062162</classIRI>
<classLabel>positive regulation of pyocyanine biosynthetic process</classLabel>
<newAxiom>'positive regulation of pyocyanine biosynthetic process' EquivalentTo 'biological_process' and ('positively regulates' some 'pyocyanine biosynthetic process')</newAxiom>
<newAxiom>'positive regulation of pyocyanine biosynthetic process' SubClassOf 'positive regulation of cellular biosynthetic process'</newAxiom>
<newAxiom>'positive regulation of pyocyanine biosynthetic process' SubClassOf 'positive regulation of nitrogen compound metabolic process'</newAxiom>
<newAxiom>'positive regulation of pyocyanine biosynthetic process' SubClassOf 'regulation of pyocyanine biosynthetic process'</newAxiom>
<newAxiom>'positive regulation of pyocyanine biosynthetic process' SubClassOf 'positive regulation of secondary metabolite biosynthetic process'</newAxiom>
<newAxiom>'positive regulation of pyocyanine biosynthetic process' SubClassOf 'positively regulates' some 'pyocyanine biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062161</classIRI>
<classLabel>regulation of pyocyanine biosynthetic process</classLabel>
<newAxiom>'regulation of pyocyanine biosynthetic process' SubClassOf 'regulation of nitrogen compound metabolic process'</newAxiom>
<newAxiom>'regulation of pyocyanine biosynthetic process' EquivalentTo 'biological_process' and ('regulates' some 'pyocyanine biosynthetic process')</newAxiom>
<newAxiom>'regulation of pyocyanine biosynthetic process' SubClassOf 'regulation of secondary metabolite biosynthetic process'</newAxiom>
<newAxiom>'regulation of pyocyanine biosynthetic process' SubClassOf 'regulates' some 'pyocyanine biosynthetic process'</newAxiom>
<newAxiom>'regulation of pyocyanine biosynthetic process' SubClassOf 'regulation of cellular biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062166</classIRI>
<classLabel>negative regulation of pseudohyphal septin ring assembly</classLabel>
<newAxiom>'negative regulation of pseudohyphal septin ring assembly' SubClassOf 'negative regulation of cytoskeleton organization'</newAxiom>
<newAxiom>'negative regulation of pseudohyphal septin ring assembly' SubClassOf 'regulation of pseudohyphal septin ring assembly'</newAxiom>
<newAxiom>'negative regulation of pseudohyphal septin ring assembly' SubClassOf 'negative regulation of organelle assembly'</newAxiom>
<newAxiom>'negative regulation of pseudohyphal septin ring assembly' SubClassOf 'negatively regulates' some 'pseudohyphal septin ring assembly'</newAxiom>
<newAxiom>'negative regulation of pseudohyphal septin ring assembly' EquivalentTo 'biological_process' and ('negatively regulates' some 'pseudohyphal septin ring assembly')</newAxiom>
<newAxiom>'negative regulation of pseudohyphal septin ring assembly' SubClassOf 'negative regulation of protein-containing complex assembly'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062165</classIRI>
<classLabel>positive regulation of pseudohyphal septin ring assembly</classLabel>
<newAxiom>'positive regulation of pseudohyphal septin ring assembly' SubClassOf 'positive regulation of cytoskeleton organization'</newAxiom>
<newAxiom>'positive regulation of pseudohyphal septin ring assembly' SubClassOf 'positively regulates' some 'pseudohyphal septin ring assembly'</newAxiom>
<newAxiom>'positive regulation of pseudohyphal septin ring assembly' SubClassOf 'positive regulation of organelle assembly'</newAxiom>
<newAxiom>'positive regulation of pseudohyphal septin ring assembly' SubClassOf 'positive regulation of protein-containing complex assembly'</newAxiom>
<newAxiom>'positive regulation of pseudohyphal septin ring assembly' SubClassOf 'regulation of pseudohyphal septin ring assembly'</newAxiom>
<newAxiom>'positive regulation of pseudohyphal septin ring assembly' EquivalentTo 'biological_process' and ('positively regulates' some 'pseudohyphal septin ring assembly')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062164</classIRI>
<classLabel>regulation of pseudohyphal septin ring assembly</classLabel>
<newAxiom>'regulation of pseudohyphal septin ring assembly' SubClassOf 'regulates' some 'pseudohyphal septin ring assembly'</newAxiom>
<newAxiom>'regulation of pseudohyphal septin ring assembly' SubClassOf 'regulation of organelle assembly'</newAxiom>
<newAxiom>'regulation of pseudohyphal septin ring assembly' SubClassOf 'regulation of cytoskeleton organization'</newAxiom>
<newAxiom>'regulation of pseudohyphal septin ring assembly' EquivalentTo 'biological_process' and ('regulates' some 'pseudohyphal septin ring assembly')</newAxiom>
<newAxiom>'regulation of pseudohyphal septin ring assembly' SubClassOf 'regulation of protein-containing complex assembly'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062163</classIRI>
<classLabel>pseudohyphal septin ring assembly</classLabel>
<newAxiom>'pseudohyphal septin ring assembly' SubClassOf 'septin ring assembly'</newAxiom>
<newAxiom>'pseudohyphal septin ring assembly' SubClassOf 'results in assembly of' some 'pseudohyphal septin ring'</newAxiom>
<newAxiom>'pseudohyphal septin ring assembly' EquivalentTo 'cellular component assembly' and ('results in assembly of' some 'pseudohyphal septin ring')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062191</classIRI>
<classLabel>galactoxylomannan biosynthetic process</classLabel>
<newAxiom>'galactoxylomannan biosynthetic process' SubClassOf 'fungal-type cell wall polysaccharide biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062189</classIRI>
<classLabel>anandamide 14,15 epoxidase activity</classLabel>
<newAxiom>'anandamide 14,15 epoxidase activity' SubClassOf 'anandamide epoxidase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/BTO_0001117</classIRI>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150146</classIRI>
<classLabel>cell junction disassembly</classLabel>
<newAxiom>'cell junction disassembly' SubClassOf 'cell junction organization'</newAxiom>
<newAxiom>'cell junction disassembly' EquivalentTo 'cellular component disassembly' and ('results in disassembly of' some 'cell junction')</newAxiom>
<newAxiom>'cell junction disassembly' SubClassOf 'cellular component disassembly'</newAxiom>
<newAxiom>'cell junction disassembly' SubClassOf 'results in disassembly of' some 'cell junction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150145</classIRI>
<classLabel>positive regulation of CD80 biosynthetic process</classLabel>
<newAxiom>'positive regulation of CD80 biosynthetic process' SubClassOf 'positive regulation of glycoprotein biosynthetic process'</newAxiom>
<newAxiom>'positive regulation of CD80 biosynthetic process' SubClassOf 'positively regulates' some 'CD80 biosynthetic process'</newAxiom>
<newAxiom>'positive regulation of CD80 biosynthetic process' EquivalentTo 'biological regulation' and ('positively regulates' some 'CD80 biosynthetic process')</newAxiom>
<newAxiom>'positive regulation of CD80 biosynthetic process' SubClassOf 'regulation of CD80 biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150147</classIRI>
<classLabel>cell-cell junction disassembly</classLabel>
<newAxiom>'cell-cell junction disassembly' SubClassOf 'results in disassembly of' some 'cell-cell junction'</newAxiom>
<newAxiom>'cell-cell junction disassembly' EquivalentTo 'cell junction disassembly' and ('results in disassembly of' some 'cell-cell junction')</newAxiom>
<newAxiom>'cell-cell junction disassembly' SubClassOf 'cell junction disassembly'</newAxiom>
<newAxiom>'cell-cell junction disassembly' SubClassOf 'cell-cell junction organization'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150140</classIRI>
<classLabel>regulation of CD86 biosynthetic process</classLabel>
<newAxiom>'regulation of CD86 biosynthetic process' SubClassOf 'regulates' some 'CD86 biosynthetic process'</newAxiom>
<newAxiom>'regulation of CD86 biosynthetic process' EquivalentTo 'biological regulation' and ('regulates' some 'CD86 biosynthetic process')</newAxiom>
<newAxiom>'regulation of CD86 biosynthetic process' SubClassOf 'regulation of glycoprotein biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150142</classIRI>
<classLabel>positive regulation of CD86 biosynthetic process</classLabel>
<newAxiom>'positive regulation of CD86 biosynthetic process' SubClassOf 'positive regulation of glycoprotein biosynthetic process'</newAxiom>
<newAxiom>'positive regulation of CD86 biosynthetic process' EquivalentTo 'biological regulation' and ('positively regulates' some 'CD86 biosynthetic process')</newAxiom>
<newAxiom>'positive regulation of CD86 biosynthetic process' SubClassOf 'regulation of CD86 biosynthetic process'</newAxiom>
<newAxiom>'positive regulation of CD86 biosynthetic process' SubClassOf 'positively regulates' some 'CD86 biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150141</classIRI>
<classLabel>negative regulation of CD86 biosynthetic process</classLabel>
<newAxiom>'negative regulation of CD86 biosynthetic process' SubClassOf 'regulation of CD86 biosynthetic process'</newAxiom>
<newAxiom>'negative regulation of CD86 biosynthetic process' SubClassOf 'negative regulation of glycoprotein biosynthetic process'</newAxiom>
<newAxiom>'negative regulation of CD86 biosynthetic process' EquivalentTo 'biological regulation' and ('negatively regulates' some 'CD86 biosynthetic process')</newAxiom>
<newAxiom>'negative regulation of CD86 biosynthetic process' SubClassOf 'negatively regulates' some 'CD86 biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150144</classIRI>
<classLabel>negative regulation of CD80 biosynthetic process</classLabel>
<newAxiom>'negative regulation of CD80 biosynthetic process' SubClassOf 'regulation of CD80 biosynthetic process'</newAxiom>
<newAxiom>'negative regulation of CD80 biosynthetic process' SubClassOf 'negative regulation of glycoprotein biosynthetic process'</newAxiom>
<newAxiom>'negative regulation of CD80 biosynthetic process' SubClassOf 'negatively regulates' some 'CD80 biosynthetic process'</newAxiom>
<newAxiom>'negative regulation of CD80 biosynthetic process' EquivalentTo 'biological regulation' and ('negatively regulates' some 'CD80 biosynthetic process')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150143</classIRI>
<classLabel>regulation of CD80 biosynthetic process</classLabel>
<newAxiom>'regulation of CD80 biosynthetic process' SubClassOf 'regulation of glycoprotein biosynthetic process'</newAxiom>
<newAxiom>'regulation of CD80 biosynthetic process' EquivalentTo 'biological regulation' and ('regulates' some 'CD80 biosynthetic process')</newAxiom>
<newAxiom>'regulation of CD80 biosynthetic process' SubClassOf 'regulates' some 'CD80 biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150135</classIRI>
<classLabel>positive regulation of interleukin-4 secretion</classLabel>
<newAxiom>'positive regulation of interleukin-4 secretion' SubClassOf 'regulation of interleukin-4 secretion'</newAxiom>
<newAxiom>'positive regulation of interleukin-4 secretion' SubClassOf 'positive regulation of cytokine secretion'</newAxiom>
<newAxiom>'positive regulation of interleukin-4 secretion' EquivalentTo 'biological regulation' and ('positively regulates' some 'interleukin-4 secretion')</newAxiom>
<newAxiom>'positive regulation of interleukin-4 secretion' SubClassOf 'positive regulation of interleukin-4 production'</newAxiom>
<newAxiom>'positive regulation of interleukin-4 secretion' SubClassOf 'positively regulates' some 'interleukin-4 secretion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150134</classIRI>
<classLabel>negative regulation of interleukin-4 secretion</classLabel>
<newAxiom>'negative regulation of interleukin-4 secretion' SubClassOf 'regulation of interleukin-4 secretion'</newAxiom>
<newAxiom>'negative regulation of interleukin-4 secretion' SubClassOf 'negative regulation of interleukin-4 production'</newAxiom>
<newAxiom>'negative regulation of interleukin-4 secretion' SubClassOf 'negatively regulates' some 'interleukin-4 secretion'</newAxiom>
<newAxiom>'negative regulation of interleukin-4 secretion' EquivalentTo 'biological regulation' and ('negatively regulates' some 'interleukin-4 secretion')</newAxiom>
<newAxiom>'negative regulation of interleukin-4 secretion' SubClassOf 'negative regulation of cytokine secretion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150137</classIRI>
<classLabel>interleukin-37 biosynthetic process</classLabel>
<newAxiom>'interleukin-37 biosynthetic process' SubClassOf 'cytokine biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150136</classIRI>
<classLabel>regulation of interleukin-37 biosynthetic process</classLabel>
<newAxiom>'regulation of interleukin-37 biosynthetic process' SubClassOf 'regulation of cytokine biosynthetic process'</newAxiom>
<newAxiom>'regulation of interleukin-37 biosynthetic process' EquivalentTo 'biological regulation' and ('regulates' some 'interleukin-37 biosynthetic process')</newAxiom>
<newAxiom>'regulation of interleukin-37 biosynthetic process' SubClassOf 'regulates' some 'interleukin-37 biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150139</classIRI>
<classLabel>positive regulation of interleukin-37 biosynthetic process</classLabel>
<newAxiom>'positive regulation of interleukin-37 biosynthetic process' SubClassOf 'regulation of interleukin-37 biosynthetic process'</newAxiom>
<newAxiom>'positive regulation of interleukin-37 biosynthetic process' EquivalentTo 'biological regulation' and ('positively regulates' some 'interleukin-37 biosynthetic process')</newAxiom>
<newAxiom>'positive regulation of interleukin-37 biosynthetic process' SubClassOf 'positive regulation of cytokine biosynthetic process'</newAxiom>
<newAxiom>'positive regulation of interleukin-37 biosynthetic process' SubClassOf 'positively regulates' some 'interleukin-37 biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150138</classIRI>
<classLabel>negative regulation of interleukin-37 biosynthetic process</classLabel>
<newAxiom>'negative regulation of interleukin-37 biosynthetic process' SubClassOf 'negatively regulates' some 'interleukin-37 biosynthetic process'</newAxiom>
<newAxiom>'negative regulation of interleukin-37 biosynthetic process' EquivalentTo 'biological regulation' and ('negatively regulates' some 'interleukin-37 biosynthetic process')</newAxiom>
<newAxiom>'negative regulation of interleukin-37 biosynthetic process' SubClassOf 'negative regulation of cytokine biosynthetic process'</newAxiom>
<newAxiom>'negative regulation of interleukin-37 biosynthetic process' SubClassOf 'regulation of interleukin-37 biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150131</classIRI>
<classLabel>negative regulation of interleukin-33 secretion</classLabel>
<newAxiom>'negative regulation of interleukin-33 secretion' SubClassOf 'negative regulation of interleukin-33 production'</newAxiom>
<newAxiom>'negative regulation of interleukin-33 secretion' EquivalentTo 'biological regulation' and ('negatively regulates' some 'interleukin-33 secretion')</newAxiom>
<newAxiom>'negative regulation of interleukin-33 secretion' SubClassOf 'regulation of interleukin-33 secretion'</newAxiom>
<newAxiom>'negative regulation of interleukin-33 secretion' SubClassOf 'negative regulation of cytokine secretion'</newAxiom>
<newAxiom>'negative regulation of interleukin-33 secretion' SubClassOf 'negatively regulates' some 'interleukin-33 secretion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150130</classIRI>
<classLabel>regulation of interleukin-33 secretion</classLabel>
<newAxiom>'regulation of interleukin-33 secretion' SubClassOf 'regulation of cytokine secretion'</newAxiom>
<newAxiom>'regulation of interleukin-33 secretion' SubClassOf 'regulation of interleukin-33 production'</newAxiom>
<newAxiom>'regulation of interleukin-33 secretion' SubClassOf 'regulates' some 'interleukin-33 secretion'</newAxiom>
<newAxiom>'regulation of interleukin-33 secretion' EquivalentTo 'biological regulation' and ('regulates' some 'interleukin-33 secretion')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150133</classIRI>
<classLabel>regulation of interleukin-4 secretion</classLabel>
<newAxiom>'regulation of interleukin-4 secretion' SubClassOf 'regulation of interleukin-4 production'</newAxiom>
<newAxiom>'regulation of interleukin-4 secretion' SubClassOf 'regulates' some 'interleukin-4 secretion'</newAxiom>
<newAxiom>'regulation of interleukin-4 secretion' SubClassOf 'regulation of cytokine secretion'</newAxiom>
<newAxiom>'regulation of interleukin-4 secretion' EquivalentTo 'biological regulation' and ('regulates' some 'interleukin-4 secretion')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150132</classIRI>
<classLabel>positive regulation of interleukin-33 secretion</classLabel>
<newAxiom>'positive regulation of interleukin-33 secretion' SubClassOf 'positively regulates' some 'interleukin-33 secretion'</newAxiom>
<newAxiom>'positive regulation of interleukin-33 secretion' SubClassOf 'positive regulation of cytokine secretion'</newAxiom>
<newAxiom>'positive regulation of interleukin-33 secretion' SubClassOf 'regulation of interleukin-33 secretion'</newAxiom>
<newAxiom>'positive regulation of interleukin-33 secretion' EquivalentTo 'biological regulation' and ('positively regulates' some 'interleukin-33 secretion')</newAxiom>
<newAxiom>'positive regulation of interleukin-33 secretion' SubClassOf 'positive regulation of interleukin-33 production'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150124</classIRI>
<classLabel>negative regulation of interleukin-33 biosynthetic process</classLabel>
<newAxiom>'negative regulation of interleukin-33 biosynthetic process' SubClassOf 'regulation of interleukin-33 biosynthetic process'</newAxiom>
<newAxiom>'negative regulation of interleukin-33 biosynthetic process' SubClassOf 'negative regulation of cytokine biosynthetic process'</newAxiom>
<newAxiom>'negative regulation of interleukin-33 biosynthetic process' SubClassOf 'negatively regulates' some 'interleukin-33 biosynthetic process'</newAxiom>
<newAxiom>'negative regulation of interleukin-33 biosynthetic process' EquivalentTo 'biological regulation' and ('negatively regulates' some 'interleukin-33 biosynthetic process')</newAxiom>
<newAxiom>'negative regulation of interleukin-33 biosynthetic process' SubClassOf 'negative regulation of interleukin-33 production'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150123</classIRI>
<classLabel>regulation of interleukin-33 biosynthetic process</classLabel>
<newAxiom>'regulation of interleukin-33 biosynthetic process' EquivalentTo 'biological regulation' and ('regulates' some 'interleukin-33 biosynthetic process')</newAxiom>
<newAxiom>'regulation of interleukin-33 biosynthetic process' SubClassOf 'regulation of interleukin-33 production'</newAxiom>
<newAxiom>'regulation of interleukin-33 biosynthetic process' SubClassOf 'regulates' some 'interleukin-33 biosynthetic process'</newAxiom>
<newAxiom>'regulation of interleukin-33 biosynthetic process' SubClassOf 'regulation of cytokine biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150126</classIRI>
<classLabel>interleukin-33 biosynthetic process</classLabel>
<newAxiom>'interleukin-33 biosynthetic process' SubClassOf 'part of' some 'interleukin-33 production'</newAxiom>
<newAxiom>'interleukin-33 biosynthetic process' SubClassOf 'organonitrogen compound biosynthetic process'</newAxiom>
<newAxiom>'interleukin-33 biosynthetic process' SubClassOf 'has primary output' some 'interleukin-33'</newAxiom>
<newAxiom>'interleukin-33 biosynthetic process' SubClassOf 'cytokine biosynthetic process'</newAxiom>
<newAxiom>'interleukin-33 biosynthetic process' EquivalentTo 'biosynthetic process' and ('has primary output' some 'interleukin-33')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150125</classIRI>
<classLabel>positive regulation of interleukin-33 biosynthetic process</classLabel>
<newAxiom>'positive regulation of interleukin-33 biosynthetic process' SubClassOf 'positively regulates' some 'interleukin-33 biosynthetic process'</newAxiom>
<newAxiom>'positive regulation of interleukin-33 biosynthetic process' SubClassOf 'positive regulation of cytokine biosynthetic process'</newAxiom>
<newAxiom>'positive regulation of interleukin-33 biosynthetic process' SubClassOf 'positive regulation of interleukin-33 production'</newAxiom>
<newAxiom>'positive regulation of interleukin-33 biosynthetic process' EquivalentTo 'biological regulation' and ('positively regulates' some 'interleukin-33 biosynthetic process')</newAxiom>
<newAxiom>'positive regulation of interleukin-33 biosynthetic process' SubClassOf 'regulation of interleukin-33 biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150128</classIRI>
<classLabel>negative regulation of interleukin-33 production</classLabel>
<newAxiom>'negative regulation of interleukin-33 production' EquivalentTo 'biological regulation' and ('negatively regulates' some 'interleukin-33 production')</newAxiom>
<newAxiom>'negative regulation of interleukin-33 production' SubClassOf 'regulation of interleukin-33 production'</newAxiom>
<newAxiom>'negative regulation of interleukin-33 production' SubClassOf 'negatively regulates' some 'interleukin-33 production'</newAxiom>
<newAxiom>'negative regulation of interleukin-33 production' SubClassOf 'negative regulation of cytokine production'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150127</classIRI>
<classLabel>regulation of interleukin-33 production</classLabel>
<newAxiom>'regulation of interleukin-33 production' SubClassOf 'regulates' some 'interleukin-33 production'</newAxiom>
<newAxiom>'regulation of interleukin-33 production' EquivalentTo 'biological regulation' and ('regulates' some 'interleukin-33 production')</newAxiom>
<newAxiom>'regulation of interleukin-33 production' SubClassOf 'regulation of cytokine production'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150129</classIRI>
<classLabel>positive regulation of interleukin-33 production</classLabel>
<newAxiom>'positive regulation of interleukin-33 production' EquivalentTo 'biological regulation' and ('positively regulates' some 'interleukin-33 production')</newAxiom>
<newAxiom>'positive regulation of interleukin-33 production' SubClassOf 'positive regulation of cytokine production'</newAxiom>
<newAxiom>'positive regulation of interleukin-33 production' SubClassOf 'positively regulates' some 'interleukin-33 production'</newAxiom>
<newAxiom>'positive regulation of interleukin-33 production' SubClassOf 'regulation of interleukin-33 production'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150120</classIRI>
<classLabel>regulation of interleukin-18 secretion</classLabel>
<newAxiom>'regulation of interleukin-18 secretion' EquivalentTo 'biological regulation' and ('regulates' some 'interleukin-18 secretion')</newAxiom>
<newAxiom>'regulation of interleukin-18 secretion' SubClassOf 'regulates' some 'interleukin-18 secretion'</newAxiom>
<newAxiom>'regulation of interleukin-18 secretion' SubClassOf 'regulation of interleukin-18 production'</newAxiom>
<newAxiom>'regulation of interleukin-18 secretion' SubClassOf 'regulation of cytokine secretion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150122</classIRI>
<classLabel>positive regulation of interleukin-18 secretion</classLabel>
<newAxiom>'positive regulation of interleukin-18 secretion' SubClassOf 'positive regulation of interleukin-18 production'</newAxiom>
<newAxiom>'positive regulation of interleukin-18 secretion' SubClassOf 'regulation of interleukin-18 secretion'</newAxiom>
<newAxiom>'positive regulation of interleukin-18 secretion' EquivalentTo 'biological regulation' and ('positively regulates' some 'interleukin-18 secretion')</newAxiom>
<newAxiom>'positive regulation of interleukin-18 secretion' SubClassOf 'positive regulation of cytokine secretion'</newAxiom>
<newAxiom>'positive regulation of interleukin-18 secretion' SubClassOf 'positively regulates' some 'interleukin-18 secretion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150121</classIRI>
<classLabel>negative regulation of interleukin-18 secretion</classLabel>
<newAxiom>'negative regulation of interleukin-18 secretion' SubClassOf 'regulation of interleukin-18 secretion'</newAxiom>
<newAxiom>'negative regulation of interleukin-18 secretion' SubClassOf 'negative regulation of cytokine secretion'</newAxiom>
<newAxiom>'negative regulation of interleukin-18 secretion' SubClassOf 'negatively regulates' some 'interleukin-18 secretion'</newAxiom>
<newAxiom>'negative regulation of interleukin-18 secretion' EquivalentTo 'biological regulation' and ('negatively regulates' some 'interleukin-18 secretion')</newAxiom>
<newAxiom>'negative regulation of interleukin-18 secretion' SubClassOf 'negative regulation of interleukin-18 production'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150115</classIRI>
<classLabel>cell-substrate junction organization</classLabel>
<newAxiom>'cell-substrate junction organization' SubClassOf 'cell junction organization'</newAxiom>
<newAxiom>'cell-substrate junction organization' SubClassOf 'results_in_organization_of' some 'cell-substrate junction'</newAxiom>
<newAxiom>'cell-substrate junction organization' EquivalentTo 'cell junction organization' and ('results_in_organization_of' some 'cell-substrate junction')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150117</classIRI>
<classLabel>positive regulation of cell-substrate junction organization</classLabel>
<newAxiom>'positive regulation of cell-substrate junction organization' SubClassOf 'positively regulates' some 'cell-substrate junction organization'</newAxiom>
<newAxiom>'positive regulation of cell-substrate junction organization' SubClassOf 'regulation of cell-substrate junction organization'</newAxiom>
<newAxiom>'positive regulation of cell-substrate junction organization' SubClassOf 'positive regulation of cellular component organization'</newAxiom>
<newAxiom>'positive regulation of cell-substrate junction organization' EquivalentTo 'biological regulation' and ('positively regulates' some 'cell-substrate junction organization')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150116</classIRI>
<classLabel>regulation of cell-substrate junction organization</classLabel>
<newAxiom>'regulation of cell-substrate junction organization' EquivalentTo 'biological regulation' and ('regulates' some 'cell-substrate junction organization')</newAxiom>
<newAxiom>'regulation of cell-substrate junction organization' SubClassOf 'regulation of cellular component organization'</newAxiom>
<newAxiom>'regulation of cell-substrate junction organization' SubClassOf 'regulates' some 'cell-substrate junction organization'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150119</classIRI>
<classLabel>negative regulation of protein localization to cell-cell junction</classLabel>
<newAxiom>'negative regulation of protein localization to cell-cell junction' EquivalentTo 'biological regulation' and ('negatively regulates' some 'protein localization to cell-cell junction')</newAxiom>
<newAxiom>'negative regulation of protein localization to cell-cell junction' SubClassOf 'regulation of protein localization to cell-cell junction'</newAxiom>
<newAxiom>'negative regulation of protein localization to cell-cell junction' SubClassOf 'negatively regulates' some 'protein localization to cell-cell junction'</newAxiom>
<newAxiom>'negative regulation of protein localization to cell-cell junction' SubClassOf 'negative regulation of biological process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150118</classIRI>
<classLabel>negative regulation of cell-substrate junction organization</classLabel>
<newAxiom>'negative regulation of cell-substrate junction organization' SubClassOf 'negative regulation of cellular component organization'</newAxiom>
<newAxiom>'negative regulation of cell-substrate junction organization' SubClassOf 'negatively regulates' some 'cell-substrate junction organization'</newAxiom>
<newAxiom>'negative regulation of cell-substrate junction organization' SubClassOf 'regulation of cell-substrate junction organization'</newAxiom>
<newAxiom>'negative regulation of cell-substrate junction organization' EquivalentTo 'biological regulation' and ('negatively regulates' some 'cell-substrate junction organization')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140399</classIRI>
<classLabel>aflatoxin B synthase activity</classLabel>
<newAxiom>'aflatoxin B synthase activity' SubClassOf 'part of' some 'aflatoxin biosynthetic process'</newAxiom>
<newAxiom>'aflatoxin B synthase activity' SubClassOf 'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140394</classIRI>
<classLabel>ATPase-coupled azole transmembrane transporter activity</classLabel>
<newAxiom>'ATPase-coupled azole transmembrane transporter activity' SubClassOf 'azole transmembrane transporter activity'</newAxiom>
<newAxiom>'ATPase-coupled azole transmembrane transporter activity' EquivalentTo 'transporter activity' and ('has_part' some 'ATPase activity') and ('transports or maintains localization of' some 'azole') and ('results in transport across' some 'membrane')</newAxiom>
<newAxiom>'ATPase-coupled azole transmembrane transporter activity' SubClassOf 'ATPase-coupled transmembrane transporter activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140393</classIRI>
<classLabel>norsolorinic acid ketoreductase activity</classLabel>
<newAxiom>'norsolorinic acid ketoreductase activity' SubClassOf 'ketoreductase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140398</classIRI>
<classLabel>versicolorin B desaturase activity</classLabel>
<newAxiom>'versicolorin B desaturase activity' SubClassOf 'oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140397</classIRI>
<classLabel>versiconal hemiacetal acetate esterase activity</classLabel>
<newAxiom>'versiconal hemiacetal acetate esterase activity' SubClassOf 'hydrolase activity, acting on ester bonds'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140396</classIRI>
<classLabel>5'-hydroxyaverantin dehydrogenase activity</classLabel>
<newAxiom>'5'-hydroxyaverantin dehydrogenase activity' SubClassOf 'oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140395</classIRI>
<classLabel>averantin hydroxylase activity</classLabel>
<newAxiom>'averantin hydroxylase activity' SubClassOf 'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen'</newAxiom>
<newAxiom>'averantin hydroxylase activity' SubClassOf 'part of' some 'aflatoxin biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140383</classIRI>
<classLabel>4-hydroxytryptamine kinase activity</classLabel>
<newAxiom>'4-hydroxytryptamine kinase activity' SubClassOf 'kinase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140382</classIRI>
<classLabel>tryptamine 4-monooxygenase activity</classLabel>
<newAxiom>'tryptamine 4-monooxygenase activity' SubClassOf 'monooxygenase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140381</classIRI>
<classLabel>4-hydroxytryptamine 4-phosphate methyltransferase activity</classLabel>
<newAxiom>'4-hydroxytryptamine 4-phosphate methyltransferase activity' SubClassOf 'methyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140380</classIRI>
<classLabel>psilocybin biosynthetic process</classLabel>
<newAxiom>'psilocybin biosynthetic process' SubClassOf 'starts with' some 'L-tryptophan decarboxylase activity'</newAxiom>
<newAxiom>'psilocybin biosynthetic process' SubClassOf 'tryptophan metabolic process'</newAxiom>
<newAxiom>'psilocybin biosynthetic process' SubClassOf 'erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process'</newAxiom>
<newAxiom>'psilocybin biosynthetic process' SubClassOf 'indole-containing compound biosynthetic process'</newAxiom>
<newAxiom>'psilocybin biosynthetic process' EquivalentTo 'biosynthetic process' and ('has_part' some 'tryptamine 4-monooxygenase activity') and ('has_part' some '4-hydroxytryptamine kinase activity') and ('starts with' some 'L-tryptophan decarboxylase activity') and ('ends with' some '4-hydroxytryptamine 4-phosphate methyltransferase activity') and ('has intermediate' some '4-hydroxytryptamine') and ('has intermediate' some 'norbaeocystin') and ('has intermediate' some 'tryptamine') and ('has primary output' some 'psilocybin') and ('has primary input' some 'L-tryptophan')</newAxiom>
<newAxiom>'psilocybin biosynthetic process' SubClassOf 'mycotoxin biosynthetic process'</newAxiom>
<newAxiom>'psilocybin biosynthetic process' SubClassOf 'ends with' some '4-hydroxytryptamine 4-phosphate methyltransferase activity'</newAxiom>
<newAxiom>'psilocybin biosynthetic process' SubClassOf 'organophosphate biosynthetic process'</newAxiom>
<newAxiom>'psilocybin biosynthetic process' SubClassOf 'phosphate-containing compound metabolic process'</newAxiom>
<newAxiom>'psilocybin biosynthetic process' SubClassOf 'has primary input' some 'L-tryptophan'</newAxiom>
<newAxiom>'psilocybin biosynthetic process' SubClassOf 'drug metabolic process'</newAxiom>
<newAxiom>'psilocybin biosynthetic process' SubClassOf 'has_part' some '4-hydroxytryptamine kinase activity'</newAxiom>
<newAxiom>'psilocybin biosynthetic process' SubClassOf 'indole alkaloid biosynthetic process'</newAxiom>
<newAxiom>'psilocybin biosynthetic process' SubClassOf 'has intermediate' some 'tryptamine'</newAxiom>
<newAxiom>'psilocybin biosynthetic process' SubClassOf 'has primary output' some 'psilocybin'</newAxiom>
<newAxiom>'psilocybin biosynthetic process' SubClassOf 'has intermediate' some '4-hydroxytryptamine'</newAxiom>
<newAxiom>'psilocybin biosynthetic process' SubClassOf 'has intermediate' some 'norbaeocystin'</newAxiom>
<newAxiom>'psilocybin biosynthetic process' SubClassOf 'has_part' some 'tryptamine 4-monooxygenase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140384</classIRI>
<classLabel>metacyclogenesis</classLabel>
<newAxiom>'metacyclogenesis' SubClassOf 'in taxon' only 'Trypanosomatidae'</newAxiom>
<newAxiom>'metacyclogenesis' SubClassOf 'development of symbiont in host'</newAxiom>
<newAxiom>'metacyclogenesis' SubClassOf 'only_in_taxon' some 'Trypanosomatidae'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>