<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
274
</numberChangedClasses>
<numberNewClasses>
50
</numberNewClasses>
<numberDeletedClasses>
89
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_37939</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_37939 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019185</classIRI>
<classLabel>snRNA-activating protein complex</classLabel>
<deletedAxiom>&apos;snRNA-activating protein complex&apos; SubClassOf &apos;nuclear transcription factor complex&apos;</deletedAxiom>
<newAxiom>&apos;snRNA-activating protein complex&apos; SubClassOf &apos;transcription factor complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034718</classIRI>
<classLabel>SMN-Gemin2 complex</classLabel>
<newAxiom>&apos;SMN-Gemin2 complex&apos; SubClassOf &apos;part of&apos; some &apos;intracellular&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_713636</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_713636 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_7785</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_7785 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_33090</classIRI>
<classLabel>Viridiplantae</classLabel>
<deletedAxiom>&apos;Fornicata&apos; DisjointWith &apos;Viridiplantae&apos;</deletedAxiom>
<deletedAxiom>&apos;Viridiplantae&apos; DisjointWith &apos;Stramenopiles&apos;</deletedAxiom>
<deletedAxiom>&apos;Viridiplantae&apos; DisjointWith &apos;Alveolata&apos;</deletedAxiom>
<deletedAxiom>&apos;Viridiplantae&apos; DisjointWith &apos;Euglenozoa&apos;</deletedAxiom>
<newAxiom>http://purl.obolibrary.org/obo/NCBITaxon_2611352 DisjointWith &apos;Viridiplantae&apos;</newAxiom>
<newAxiom>http://purl.obolibrary.org/obo/NCBITaxon_2698737 DisjointWith &apos;Viridiplantae&apos;</newAxiom>
<newAxiom>http://purl.obolibrary.org/obo/NCBITaxon_2611341 DisjointWith &apos;Viridiplantae&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_267407</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_267407 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010232</classIRI>
<classLabel>vascular transport</classLabel>
<deletedAxiom>&apos;vascular transport&apos; SubClassOf &apos;multicellular organismal process&apos;</deletedAxiom>
<newAxiom>&apos;vascular transport&apos; SubClassOf &apos;vascular process in circulatory system&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_194550</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_194550 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097717</classIRI>
<classLabel>copper ion transport across blood-cerebrospinal fluid barrier</classLabel>
<deletedAxiom>&apos;copper ion transport across blood-cerebrospinal fluid barrier&apos; SubClassOf &apos;results in transport across&apos; some &apos;blood-cerebrospinal fluid barrier&apos;</deletedAxiom>
<newAxiom>&apos;copper ion transport across blood-cerebrospinal fluid barrier&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0150195</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000783</classIRI>
<classLabel>nuclear telomere cap complex</classLabel>
<deletedAxiom>&apos;nuclear telomere cap complex&apos; SubClassOf &apos;part of&apos; some &apos;nuclear chromosome, telomeric region&apos;</deletedAxiom>
<newAxiom>&apos;nuclear telomere cap complex&apos; SubClassOf &apos;part of&apos; some &apos;nucleus&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000782</classIRI>
<classLabel>telomere cap complex</classLabel>
<deletedAxiom>&apos;telomere cap complex&apos; SubClassOf &apos;part of&apos; some &apos;chromosome, telomeric region&apos;</deletedAxiom>
<newAxiom>&apos;telomere cap complex&apos; SubClassOf &apos;part of&apos; some http://purl.obolibrary.org/obo/GO_0140445</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_3312</classIRI>
<classLabel>Coniferophyta</classLabel>
<deletedAxiom>&apos;Gnetidae&apos; DisjointWith &apos;Coniferophyta&apos;</deletedAxiom>
<newAxiom>&apos;Coniferophyta&apos; DisjointWith http://purl.obolibrary.org/obo/NCBITaxon_3372</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_3290</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_3290 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_3176</classIRI>
<classLabel>Zygnematales</classLabel>
<deletedAxiom>&apos;Zygnematales&apos; SubClassOf &apos;Zygnemophyceae&apos;</deletedAxiom>
<newAxiom>&apos;Zygnematales&apos; SubClassOf http://purl.obolibrary.org/obo/NCBITaxon_2684882</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000439</classIRI>
<classLabel>transcription factor TFIIH core complex</classLabel>
<newAxiom>&apos;transcription factor TFIIH core complex&apos; SubClassOf &apos;part of&apos; some &apos;nucleus&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097363</classIRI>
<classLabel>protein O-GlcNAc transferase activity</classLabel>
<deletedAxiom>&apos;protein O-GlcNAc transferase activity&apos; SubClassOf &apos;UDP-glycosyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;protein O-GlcNAc transferase activity&apos; SubClassOf &apos;transferase activity, transferring glycosyl groups&apos;</newAxiom>
<newAxiom>&apos;protein O-GlcNAc transferase activity&apos; SubClassOf &apos;catalytic activity, acting on a protein&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000637</classIRI>
<classLabel>positive regulation of gene silencing by miRNA</classLabel>
<newAxiom>&apos;positive regulation of gene silencing by miRNA&apos; SubClassOf &apos;positive regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon#_taxonomic_rank</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon#_taxonomic_rank SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990152</classIRI>
<classLabel>protein localization to telomeric heterochromatin</classLabel>
<deletedAxiom>&apos;protein localization to telomeric heterochromatin&apos; SubClassOf &apos;protein localization to heterochromatin&apos;</deletedAxiom>
<deletedAxiom>&apos;protein localization to telomeric heterochromatin&apos; SubClassOf &apos;protein localization to chromosome, telomeric region&apos;</deletedAxiom>
<deletedAxiom>&apos;protein localization to telomeric heterochromatin&apos; SubClassOf &apos;has target end location&apos; some &apos;telomeric heterochromatin&apos;</deletedAxiom>
<deletedAxiom>&apos;protein localization to telomeric heterochromatin&apos; EquivalentTo &apos;protein localization&apos; and (&apos;has target end location&apos; some &apos;telomeric heterochromatin&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000183</classIRI>
<classLabel>chromatin silencing at rDNA</classLabel>
<deletedAxiom>&apos;chromatin silencing at rDNA&apos; SubClassOf &apos;chromatin silencing&apos;</deletedAxiom>
<newAxiom>&apos;chromatin silencing at rDNA&apos; SubClassOf &apos;heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_131550</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_131550 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000120</classIRI>
<classLabel>RNA polymerase I transcription factor complex</classLabel>
<deletedAxiom>&apos;RNA polymerase I transcription factor complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;capable of&apos; some &apos;regulation of transcription by RNA polymerase I&apos;)</deletedAxiom>
<deletedAxiom>&apos;RNA polymerase I transcription factor complex&apos; SubClassOf &apos;nuclear transcription factor complex&apos;</deletedAxiom>
<deletedAxiom>&apos;RNA polymerase I transcription factor complex&apos; SubClassOf &apos;capable of&apos; some &apos;regulation of transcription by RNA polymerase I&apos;</deletedAxiom>
<newAxiom>&apos;RNA polymerase I transcription factor complex&apos; SubClassOf &apos;transcription factor complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990219</classIRI>
<classLabel>positive regulation by symbiont of host protein levels</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host protein levels&apos; SubClassOf &apos;modulation by symbiont of host protein levels&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990214</classIRI>
<classLabel>negative regulation by symbiont of host protein levels</classLabel>
<deletedAxiom>&apos;negative regulation by symbiont of host protein levels&apos; SubClassOf &apos;modulation by symbiont of host protein levels&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990243</classIRI>
<classLabel>atf1-pcr1 complex</classLabel>
<newAxiom>&apos;atf1-pcr1 complex&apos; SubClassOf &apos;capable of&apos; some &apos;DNA-binding transcription factor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990198</classIRI>
<classLabel>ModE complex</classLabel>
<deletedAxiom>&apos;ModE complex&apos; SubClassOf &apos;cytoplasmic transcription factor complex&apos;</deletedAxiom>
<newAxiom>&apos;ModE complex&apos; SubClassOf &apos;in taxon&apos; only &apos;Bacteria&apos;</newAxiom>
<newAxiom>&apos;ModE complex&apos; SubClassOf &apos;transcription factor complex&apos;</newAxiom>
<newAxiom>&apos;ModE complex&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Bacteria&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_3027</classIRI>
<classLabel>Cryptophyta</classLabel>
<deletedAxiom>&apos;Cryptophyta&apos; DisjointWith &apos;Alveolata&apos;</deletedAxiom>
<deletedAxiom>&apos;Fornicata&apos; DisjointWith &apos;Cryptophyta&apos;</deletedAxiom>
<deletedAxiom>&apos;Cryptophyta&apos; DisjointWith &apos;Euglenozoa&apos;</deletedAxiom>
<deletedAxiom>&apos;Cryptophyta&apos; DisjointWith &apos;Stramenopiles&apos;</deletedAxiom>
<newAxiom>http://purl.obolibrary.org/obo/NCBITaxon_2698737 DisjointWith &apos;Cryptophyta&apos;</newAxiom>
<newAxiom>http://purl.obolibrary.org/obo/NCBITaxon_2611341 DisjointWith &apos;Cryptophyta&apos;</newAxiom>
<newAxiom>http://purl.obolibrary.org/obo/NCBITaxon_2611352 DisjointWith &apos;Cryptophyta&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990378</classIRI>
<classLabel>upstream stimulatory factor complex</classLabel>
<newAxiom>&apos;upstream stimulatory factor complex&apos; SubClassOf &apos;part of&apos; some &apos;nucleus&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000749</classIRI>
<classLabel>positive regulation of chromatin silencing at rDNA</classLabel>
<deletedAxiom>&apos;positive regulation of chromatin silencing at rDNA&apos; SubClassOf &apos;positive regulation of chromatin silencing&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of chromatin silencing at rDNA&apos; SubClassOf &apos;positive regulation of heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038004</classIRI>
<classLabel>epidermal growth factor receptor ligand maturation</classLabel>
<deletedAxiom>&apos;epidermal growth factor receptor ligand maturation&apos; SubClassOf &apos;protein maturation&apos;</deletedAxiom>
<deletedAxiom>&apos;epidermal growth factor receptor ligand maturation&apos; SubClassOf &apos;signal maturation&apos;</deletedAxiom>
<deletedAxiom>&apos;epidermal growth factor receptor ligand maturation&apos; SubClassOf &apos;positive regulation of epidermal growth factor receptor signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;epidermal growth factor receptor ligand maturation&apos; SubClassOf &apos;has_part&apos; some &apos;membrane protein ectodomain proteolysis&apos;</newAxiom>
<newAxiom>&apos;epidermal growth factor receptor ligand maturation&apos; SubClassOf &apos;peptide hormone processing&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038005</classIRI>
<classLabel>peptide bond cleavage involved in epidermal growth factor receptor ligand maturation</classLabel>
<deletedAxiom>&apos;peptide bond cleavage involved in epidermal growth factor receptor ligand maturation&apos; EquivalentTo &apos;protein processing&apos; and (&apos;part of&apos; some &apos;epidermal growth factor receptor ligand maturation&apos;)</deletedAxiom>
<deletedAxiom>&apos;peptide bond cleavage involved in epidermal growth factor receptor ligand maturation&apos; SubClassOf &apos;has_part&apos; some &apos;membrane protein ectodomain proteolysis&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide bond cleavage involved in epidermal growth factor receptor ligand maturation&apos; SubClassOf &apos;part of&apos; some &apos;epidermal growth factor receptor ligand maturation&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide bond cleavage involved in epidermal growth factor receptor ligand maturation&apos; SubClassOf &apos;protein processing&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014045</classIRI>
<classLabel>establishment of endothelial blood-brain barrier</classLabel>
<deletedAxiom>&apos;establishment of endothelial blood-brain barrier&apos; SubClassOf &apos;part of&apos; some &apos;central nervous system development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004584</classIRI>
<classLabel>dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity</classLabel>
<deletedAxiom>&apos;dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity&apos; SubClassOf &apos;mannosyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_3666</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_3666 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043915</classIRI>
<classLabel>L-seryl-tRNA(Sec) kinase activity</classLabel>
<newAxiom>&apos;L-seryl-tRNA(Sec) kinase activity&apos; SubClassOf &apos;kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_33634</classIRI>
<classLabel>Stramenopiles</classLabel>
<deletedAxiom>&apos;Stramenopiles&apos; DisjointWith &apos;Glaucocystophyceae&apos;</deletedAxiom>
<deletedAxiom>&apos;Fornicata&apos; DisjointWith &apos;Stramenopiles&apos;</deletedAxiom>
<deletedAxiom>&apos;Stramenopiles&apos; DisjointWith &apos;Amoebozoa&apos;</deletedAxiom>
<deletedAxiom>&apos;Viridiplantae&apos; DisjointWith &apos;Stramenopiles&apos;</deletedAxiom>
<deletedAxiom>&apos;Stramenopiles&apos; DisjointWith &apos;Euglenozoa&apos;</deletedAxiom>
<deletedAxiom>&apos;Cryptophyta&apos; DisjointWith &apos;Stramenopiles&apos;</deletedAxiom>
<deletedAxiom>&apos;Stramenopiles&apos; SubClassOf &apos;Eukaryota&apos;</deletedAxiom>
<deletedAxiom>&apos;Opisthokonta&apos; DisjointWith &apos;Stramenopiles&apos;</deletedAxiom>
<newAxiom>&apos;Stramenopiles&apos; SubClassOf http://purl.obolibrary.org/obo/NCBITaxon_2698737</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_33630</classIRI>
<classLabel>Alveolata</classLabel>
<deletedAxiom>&apos;Cryptophyta&apos; DisjointWith &apos;Alveolata&apos;</deletedAxiom>
<deletedAxiom>&apos;Fornicata&apos; DisjointWith &apos;Alveolata&apos;</deletedAxiom>
<deletedAxiom>&apos;Alveolata&apos; DisjointWith &apos;Glaucocystophyceae&apos;</deletedAxiom>
<deletedAxiom>&apos;Alveolata&apos; DisjointWith &apos;Euglenozoa&apos;</deletedAxiom>
<deletedAxiom>&apos;Opisthokonta&apos; DisjointWith &apos;Alveolata&apos;</deletedAxiom>
<deletedAxiom>&apos;Viridiplantae&apos; DisjointWith &apos;Alveolata&apos;</deletedAxiom>
<deletedAxiom>&apos;Alveolata&apos; SubClassOf &apos;Eukaryota&apos;</deletedAxiom>
<deletedAxiom>&apos;Alveolata&apos; DisjointWith &apos;Amoebozoa&apos;</deletedAxiom>
<newAxiom>&apos;Alveolata&apos; SubClassOf http://purl.obolibrary.org/obo/NCBITaxon_2698737</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043725</classIRI>
<classLabel>2-keto-3-deoxygluconate aldolase activity</classLabel>
<deletedAxiom>&apos;2-keto-3-deoxygluconate aldolase activity&apos; SubClassOf &apos;hydro-lyase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_33682</classIRI>
<classLabel>Euglenozoa</classLabel>
<deletedAxiom>&apos;Euglenozoa&apos; DisjointWith &apos;Amoebozoa&apos;</deletedAxiom>
<deletedAxiom>&apos;Cryptophyta&apos; DisjointWith &apos;Euglenozoa&apos;</deletedAxiom>
<deletedAxiom>&apos;Alveolata&apos; DisjointWith &apos;Euglenozoa&apos;</deletedAxiom>
<deletedAxiom>&apos;Euglenozoa&apos; DisjointWith &apos;Glaucocystophyceae&apos;</deletedAxiom>
<deletedAxiom>&apos;Euglenozoa&apos; SubClassOf &apos;Eukaryota&apos;</deletedAxiom>
<deletedAxiom>&apos;Stramenopiles&apos; DisjointWith &apos;Euglenozoa&apos;</deletedAxiom>
<deletedAxiom>&apos;Fornicata&apos; DisjointWith &apos;Euglenozoa&apos;</deletedAxiom>
<deletedAxiom>&apos;Opisthokonta&apos; DisjointWith &apos;Euglenozoa&apos;</deletedAxiom>
<deletedAxiom>&apos;Viridiplantae&apos; DisjointWith &apos;Euglenozoa&apos;</deletedAxiom>
<newAxiom>&apos;Euglenozoa&apos; SubClassOf http://purl.obolibrary.org/obo/NCBITaxon_2611352</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://www.w3.org/2002/07/owl#Nothing</classIRI>
<deletedAxiom>http://www.w3.org/2002/07/owl#Nothing SubClassOf http://www.w3.org/2002/07/owl#Nothing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_92244</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_92244 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_1069640</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_1069640 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_33154</classIRI>
<classLabel>Opisthokonta</classLabel>
<deletedAxiom>&apos;Fornicata&apos; DisjointWith &apos;Opisthokonta&apos;</deletedAxiom>
<deletedAxiom>&apos;Opisthokonta&apos; DisjointWith &apos;Alveolata&apos;</deletedAxiom>
<deletedAxiom>&apos;Opisthokonta&apos; DisjointWith &apos;Stramenopiles&apos;</deletedAxiom>
<deletedAxiom>&apos;Opisthokonta&apos; DisjointWith &apos;Euglenozoa&apos;</deletedAxiom>
<newAxiom>http://purl.obolibrary.org/obo/NCBITaxon_2698737 DisjointWith &apos;Opisthokonta&apos;</newAxiom>
<newAxiom>http://purl.obolibrary.org/obo/NCBITaxon_2611352 DisjointWith &apos;Opisthokonta&apos;</newAxiom>
<newAxiom>http://purl.obolibrary.org/obo/NCBITaxon_2611341 DisjointWith &apos;Opisthokonta&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_195054</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_195054 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_33317</classIRI>
<classLabel>Protostomia</classLabel>
<deletedAxiom>&apos;Protostomia&apos; DisjointWith &apos;Platyhelminthes&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_33511</classIRI>
<classLabel>Deuterostomia</classLabel>
<deletedAxiom>&apos;Deuterostomia&apos; DisjointWith &apos;Platyhelminthes&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033664</classIRI>
<classLabel>positive regulation by symbiont of host defense-related protein level</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host defense-related protein level&apos; SubClassOf &apos;modulation by symbiont of host defense-related protein level&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host defense-related protein level&apos; SubClassOf &apos;induction by symbiont of host defense response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033662</classIRI>
<classLabel>modulation by symbiont of host defense-related protein level</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host defense-related protein level&apos; SubClassOf &apos;modulation by symbiont of host defense response&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by symbiont of host defense-related protein level&apos; SubClassOf &apos;modulation by symbiont of host protein levels&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033663</classIRI>
<classLabel>negative regulation by symbiont of host defense-related protein level</classLabel>
<deletedAxiom>&apos;negative regulation by symbiont of host defense-related protein level&apos; SubClassOf &apos;suppression of host defenses by symbiont&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation by symbiont of host defense-related protein level&apos; SubClassOf &apos;modulation by symbiont of host defense-related protein level&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070321</classIRI>
<classLabel>regulation of translation in response to nitrogen starvation</classLabel>
<deletedAxiom>&apos;regulation of translation in response to nitrogen starvation&apos; SubClassOf &apos;cellular response to nitrogen starvation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of translation in response to nitrogen starvation&apos; SubClassOf &apos;regulation of translation in response to stress&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070322</classIRI>
<classLabel>negative regulation of translation in response to nitrogen starvation</classLabel>
<deletedAxiom>&apos;negative regulation of translation in response to nitrogen starvation&apos; SubClassOf &apos;negative regulation of translation in response to stress&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of translation in response to nitrogen starvation&apos; SubClassOf &apos;regulation of translation in response to nitrogen starvation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070323</classIRI>
<classLabel>positive regulation of translation in response to nitrogen starvation</classLabel>
<deletedAxiom>&apos;positive regulation of translation in response to nitrogen starvation&apos; SubClassOf &apos;regulation of translation in response to nitrogen starvation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of translation in response to nitrogen starvation&apos; SubClassOf &apos;positive regulation of translation in response to stress&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PATO_0001236</classIRI>
<classLabel>process quality</classLabel>
<newAxiom>&apos;process quality&apos; DisjointWith &apos;physical object quality&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PATO_0001241</classIRI>
<classLabel>physical object quality</classLabel>
<newAxiom>&apos;process quality&apos; DisjointWith &apos;physical object quality&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_46226</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_46226 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_46225</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_46225 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060906</classIRI>
<classLabel>negative regulation of chromatin silencing by small RNA</classLabel>
<deletedAxiom>&apos;negative regulation of chromatin silencing by small RNA&apos; SubClassOf &apos;negative regulation of chromatin silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of chromatin silencing by small RNA&apos; SubClassOf &apos;negative regulation of gene silencing by RNA&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of chromatin silencing by small RNA&apos; SubClassOf &apos;negative regulation of heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060856</classIRI>
<classLabel>establishment of blood-brain barrier</classLabel>
<newAxiom>&apos;establishment of blood-brain barrier&apos; SubClassOf &apos;part of&apos; some &apos;central nervous system development&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_6403</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_6403 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_460864</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_460864 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035633</classIRI>
<classLabel>maintenance of permeability of blood-brain barrier</classLabel>
<deletedAxiom>&apos;maintenance of permeability of blood-brain barrier&apos; SubClassOf &apos;regulation of biological quality&apos;</deletedAxiom>
<newAxiom>&apos;maintenance of permeability of blood-brain barrier&apos; SubClassOf &apos;tissue homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035638</classIRI>
<classLabel>signal maturation</classLabel>
<deletedAxiom>&apos;signal maturation&apos; SubClassOf &apos;part of&apos; some &apos;positive regulation of signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;signal maturation&apos; SubClassOf &apos;cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_12355</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_12355 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_327817</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_327817 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_6157</classIRI>
<classLabel>Platyhelminthes</classLabel>
<deletedAxiom>&apos;Deuterostomia&apos; DisjointWith &apos;Platyhelminthes&apos;</deletedAxiom>
<deletedAxiom>&apos;Platyhelminthes&apos; SubClassOf &apos;Bilateria&apos;</deletedAxiom>
<deletedAxiom>&apos;Protostomia&apos; DisjointWith &apos;Platyhelminthes&apos;</deletedAxiom>
<newAxiom>&apos;Platyhelminthes&apos; SubClassOf http://purl.obolibrary.org/obo/NCBITaxon_1206795</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_1525717</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_1525717 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_85578</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_85578 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098964</classIRI>
<classLabel>anterograde dendritic transport of messenger ribonucleoprotein complex</classLabel>
<deletedAxiom>&apos;anterograde dendritic transport of messenger ribonucleoprotein complex&apos; SubClassOf &apos;protein localization to synapse&apos;</deletedAxiom>
<newAxiom>&apos;anterograde dendritic transport of messenger ribonucleoprotein complex&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0062237</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098968</classIRI>
<classLabel>neurotransmitter receptor transport postsynaptic membrane to endosome</classLabel>
<newAxiom>&apos;neurotransmitter receptor transport postsynaptic membrane to endosome&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0062237</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098971</classIRI>
<classLabel>anterograde dendritic transport of neurotransmitter receptor complex</classLabel>
<newAxiom>&apos;anterograde dendritic transport of neurotransmitter receptor complex&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0062237</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035390</classIRI>
<classLabel>establishment of chromatin silencing at telomere</classLabel>
<deletedAxiom>&apos;establishment of chromatin silencing at telomere&apos; SubClassOf &apos;part of&apos; some &apos;chromatin silencing at telomere&apos;</deletedAxiom>
<deletedAxiom>&apos;establishment of chromatin silencing at telomere&apos; SubClassOf &apos;occurs in&apos; some &apos;chromosome, telomeric region&apos;</deletedAxiom>
<deletedAxiom>&apos;establishment of chromatin silencing at telomere&apos; SubClassOf &apos;establishment of chromatin silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;establishment of chromatin silencing at telomere&apos; EquivalentTo &apos;establishment of chromatin silencing&apos; and (&apos;occurs in&apos; some &apos;chromosome, telomeric region&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035391</classIRI>
<classLabel>maintenance of chromatin silencing at silent mating-type cassette</classLabel>
<deletedAxiom>&apos;maintenance of chromatin silencing at silent mating-type cassette&apos; SubClassOf &apos;maintenance of chromatin silencing&apos;</deletedAxiom>
<newAxiom>&apos;maintenance of chromatin silencing at silent mating-type cassette&apos; SubClassOf &apos;heterochromatin maintenance&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035392</classIRI>
<classLabel>maintenance of chromatin silencing at telomere</classLabel>
<deletedAxiom>&apos;maintenance of chromatin silencing at telomere&apos; SubClassOf &apos;maintenance of chromatin silencing&apos;</deletedAxiom>
<newAxiom>&apos;maintenance of chromatin silencing at telomere&apos; SubClassOf &apos;heterochromatin maintenance&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035389</classIRI>
<classLabel>establishment of chromatin silencing at silent mating-type cassette</classLabel>
<deletedAxiom>&apos;establishment of chromatin silencing at silent mating-type cassette&apos; SubClassOf &apos;establishment of chromatin silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;establishment of chromatin silencing at silent mating-type cassette&apos; SubClassOf &apos;part of&apos; some &apos;chromatin silencing at silent mating-type cassette&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001818</classIRI>
<classLabel>negative regulation of cytokine production</classLabel>
<newAxiom>&apos;negative regulation of cytokine production&apos; SubClassOf &apos;negative regulation of gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001819</classIRI>
<classLabel>positive regulation of cytokine production</classLabel>
<newAxiom>&apos;positive regulation of cytokine production&apos; SubClassOf &apos;positive regulation of gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001816</classIRI>
<classLabel>cytokine production</classLabel>
<newAxiom>&apos;cytokine production&apos; SubClassOf &apos;gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001817</classIRI>
<classLabel>regulation of cytokine production</classLabel>
<newAxiom>&apos;regulation of cytokine production&apos; SubClassOf &apos;regulation of gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060149</classIRI>
<classLabel>negative regulation of posttranscriptional gene silencing</classLabel>
<deletedAxiom>&apos;negative regulation of posttranscriptional gene silencing&apos; SubClassOf &apos;negative regulation of gene silencing&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of posttranscriptional gene silencing&apos; SubClassOf &apos;negative regulation of biological process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060147</classIRI>
<classLabel>regulation of posttranscriptional gene silencing</classLabel>
<deletedAxiom>&apos;regulation of posttranscriptional gene silencing&apos; SubClassOf &apos;regulation of gene silencing&apos;</deletedAxiom>
<newAxiom>&apos;regulation of posttranscriptional gene silencing&apos; SubClassOf &apos;regulation of gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060148</classIRI>
<classLabel>positive regulation of posttranscriptional gene silencing</classLabel>
<deletedAxiom>&apos;positive regulation of posttranscriptional gene silencing&apos; SubClassOf &apos;positive regulation of cellular process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of posttranscriptional gene silencing&apos; SubClassOf &apos;positive regulation of biological process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_1206745</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_1206745 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905112</classIRI>
<classLabel>regulation of centromere clustering at the mitotic nuclear envelope</classLabel>
<deletedAxiom>&apos;regulation of centromere clustering at the mitotic nuclear envelope&apos; SubClassOf &apos;regulation of mitotic cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of centromere clustering at the mitotic nuclear envelope&apos; SubClassOf &apos;regulates&apos; some &apos;centromere clustering at the mitotic nuclear envelope&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of centromere clustering at the mitotic nuclear envelope&apos; SubClassOf &apos;regulation of cell cycle process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of centromere clustering at the mitotic nuclear envelope&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of centromere clustering at the mitotic nuclear envelope&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;centromere clustering at the mitotic nuclear envelope&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_1206794</classIRI>
<classLabel>Ecdysozoa</classLabel>
<newAxiom>&apos;Ecdysozoa&apos; DisjointWith http://purl.obolibrary.org/obo/NCBITaxon_2697495</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905113</classIRI>
<classLabel>positive regulation of centromere clustering at the mitotic nuclear envelope</classLabel>
<deletedAxiom>&apos;positive regulation of centromere clustering at the mitotic nuclear envelope&apos; SubClassOf &apos;regulation of centromere clustering at the mitotic nuclear envelope&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of centromere clustering at the mitotic nuclear envelope&apos; SubClassOf &apos;positive regulation of cell cycle process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of centromere clustering at the mitotic nuclear envelope&apos; SubClassOf &apos;positively regulates&apos; some &apos;centromere clustering at the mitotic nuclear envelope&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of centromere clustering at the mitotic nuclear envelope&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;centromere clustering at the mitotic nuclear envelope&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of centromere clustering at the mitotic nuclear envelope&apos; SubClassOf &apos;positive regulation of mitotic cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of centromere clustering at the mitotic nuclear envelope&apos; SubClassOf &apos;positive regulation of cellular protein localization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_61172</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_61172 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_65702</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_65702 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_51290</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_51290 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905548</classIRI>
<classLabel>negative regulation of telomeric heterochromatin assembly</classLabel>
<deletedAxiom>&apos;negative regulation of telomeric heterochromatin assembly&apos; SubClassOf &apos;negative regulation of heterochromatin assembly&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of telomeric heterochromatin assembly&apos; SubClassOf &apos;negative regulation of chromatin assembly or disassembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905549</classIRI>
<classLabel>positive regulation of telomeric heterochromatin assembly</classLabel>
<deletedAxiom>&apos;positive regulation of telomeric heterochromatin assembly&apos; SubClassOf &apos;positive regulation of heterochromatin assembly&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of telomeric heterochromatin assembly&apos; SubClassOf &apos;positive regulation of cellular component biogenesis&apos;</newAxiom>
<newAxiom>&apos;positive regulation of telomeric heterochromatin assembly&apos; SubClassOf &apos;positive regulation of chromatin assembly or disassembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905547</classIRI>
<classLabel>regulation of telomeric heterochromatin assembly</classLabel>
<deletedAxiom>&apos;regulation of telomeric heterochromatin assembly&apos; SubClassOf &apos;regulation of heterochromatin assembly&apos;</deletedAxiom>
<newAxiom>&apos;regulation of telomeric heterochromatin assembly&apos; SubClassOf &apos;regulation of chromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_1559980</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_1559980 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_1559979</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_1559979 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_89912</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_89912 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905603</classIRI>
<classLabel>regulation of maintenance of permeability of blood-brain barrier</classLabel>
<deletedAxiom>&apos;regulation of maintenance of permeability of blood-brain barrier&apos; SubClassOf &apos;regulates&apos; some &apos;maintenance of permeability of blood-brain barrier&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of maintenance of permeability of blood-brain barrier&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;maintenance of permeability of blood-brain barrier&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of maintenance of permeability of blood-brain barrier&apos; SubClassOf &apos;regulation of biological quality&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of maintenance of permeability of blood-brain barrier&apos; SubClassOf &apos;regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of maintenance of permeability of blood-brain barrier&apos; SubClassOf &apos;part of&apos; some &apos;maintenance of permeability of blood-brain barrier&apos;</newAxiom>
<newAxiom>&apos;regulation of maintenance of permeability of blood-brain barrier&apos; SubClassOf &apos;regulation of vascular permeability&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905604</classIRI>
<classLabel>negative regulation of maintenance of permeability of blood-brain barrier</classLabel>
<deletedAxiom>&apos;negative regulation of maintenance of permeability of blood-brain barrier&apos; SubClassOf &apos;negative regulation of biological process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of maintenance of permeability of blood-brain barrier&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;maintenance of permeability of blood-brain barrier&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of maintenance of permeability of blood-brain barrier&apos; SubClassOf &apos;negatively regulates&apos; some &apos;maintenance of permeability of blood-brain barrier&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of maintenance of permeability of blood-brain barrier&apos; SubClassOf &apos;negative regulation of vascular permeability&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905605</classIRI>
<classLabel>positive regulation of maintenance of permeability of blood-brain barrier</classLabel>
<deletedAxiom>&apos;positive regulation of maintenance of permeability of blood-brain barrier&apos; SubClassOf &apos;positively regulates&apos; some &apos;maintenance of permeability of blood-brain barrier&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of maintenance of permeability of blood-brain barrier&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;maintenance of permeability of blood-brain barrier&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of maintenance of permeability of blood-brain barrier&apos; SubClassOf &apos;positive regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of maintenance of permeability of blood-brain barrier&apos; SubClassOf &apos;positive regulation of vascular permeability&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_27232</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_27232 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005724</classIRI>
<classLabel>nuclear telomeric heterochromatin</classLabel>
<deletedAxiom>&apos;nuclear telomeric heterochromatin&apos; SubClassOf &apos;part of&apos; some &apos;nuclear chromosome, telomeric region&apos;</deletedAxiom>
<deletedAxiom>&apos;nuclear telomeric heterochromatin&apos; SubClassOf &apos;telomeric heterochromatin&apos;</deletedAxiom>
<deletedAxiom>&apos;nuclear telomeric heterochromatin&apos; SubClassOf &apos;nuclear heterochromatin&apos;</deletedAxiom>
<deletedAxiom>&apos;nuclear telomeric heterochromatin&apos; EquivalentTo &apos;telomeric heterochromatin&apos; and (&apos;part of&apos; some &apos;nuclear chromosome&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030702</classIRI>
<classLabel>chromatin silencing at centromere</classLabel>
<deletedAxiom>&apos;chromatin silencing at centromere&apos; SubClassOf &apos;chromatin silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;chromatin silencing at centromere&apos; SubClassOf &apos;occurs in&apos; some &apos;chromosome, centromeric region&apos;</deletedAxiom>
<deletedAxiom>&apos;chromatin silencing at centromere&apos; EquivalentTo &apos;chromatin silencing&apos; and (&apos;occurs in&apos; some &apos;chromosome, centromeric region&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030616</classIRI>
<classLabel>transforming growth factor beta receptor, common-partner cytoplasmic mediator activity</classLabel>
<deletedAxiom>&apos;transforming growth factor beta receptor, common-partner cytoplasmic mediator activity&apos; SubClassOf &apos;transforming growth factor beta receptor, cytoplasmic mediator activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030617</classIRI>
<classLabel>transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity</classLabel>
<deletedAxiom>&apos;transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity&apos; SubClassOf &apos;transforming growth factor beta receptor, cytoplasmic mediator activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030618</classIRI>
<classLabel>transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity</classLabel>
<deletedAxiom>&apos;transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity&apos; SubClassOf &apos;transforming growth factor beta receptor, cytoplasmic mediator activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005667</classIRI>
<classLabel>transcription factor complex</classLabel>
<deletedAxiom>&apos;transcription factor complex&apos; SubClassOf &apos;capable of&apos; some &apos;DNA-binding transcription factor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;transcription factor complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;capable of&apos; some &apos;DNA-binding transcription factor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;transcription factor complex&apos; SubClassOf &apos;part of&apos; some &apos;intracellular&apos;</deletedAxiom>
<newAxiom>&apos;transcription factor complex&apos; SubClassOf &apos;capable of&apos; some &apos;transcription regulator activity&apos;</newAxiom>
<newAxiom>&apos;transcription factor complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;capable of&apos; some &apos;transcription regulator activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005677</classIRI>
<classLabel>chromatin silencing complex</classLabel>
<deletedAxiom>&apos;chromatin silencing complex&apos; SubClassOf &apos;nuclear transcriptional repressor complex&apos;</deletedAxiom>
<newAxiom>&apos;chromatin silencing complex&apos; SubClassOf &apos;part of&apos; some &apos;nucleus&apos;</newAxiom>
<newAxiom>&apos;chromatin silencing complex&apos; SubClassOf &apos;protein-containing complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030466</classIRI>
<classLabel>chromatin silencing at silent mating-type cassette</classLabel>
<deletedAxiom>&apos;chromatin silencing at silent mating-type cassette&apos; SubClassOf &apos;chromatin silencing&apos;</deletedAxiom>
<newAxiom>&apos;chromatin silencing at silent mating-type cassette&apos; SubClassOf &apos;heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_451456</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_451456 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900370</classIRI>
<classLabel>positive regulation of RNA interference</classLabel>
<newAxiom>&apos;positive regulation of RNA interference&apos; SubClassOf &apos;positive regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044831</classIRI>
<classLabel>modulation by virus of host cytokine production</classLabel>
<newAxiom>&apos;modulation by virus of host cytokine production&apos; SubClassOf &apos;modulation by virus of host gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044798</classIRI>
<classLabel>nuclear transcription factor complex</classLabel>
<deletedAxiom>&apos;nuclear transcription factor complex&apos; EquivalentTo &apos;transcription factor complex&apos; and (&apos;part of&apos; some &apos;nucleus&apos;)</deletedAxiom>
<deletedAxiom>&apos;nuclear transcription factor complex&apos; SubClassOf &apos;part of&apos; some &apos;nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;nuclear transcription factor complex&apos; SubClassOf &apos;transcription factor complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044797</classIRI>
<classLabel>cytoplasmic transcription factor complex</classLabel>
<deletedAxiom>&apos;cytoplasmic transcription factor complex&apos; EquivalentTo &apos;transcription factor complex&apos; and (&apos;part of&apos; some &apos;cytoplasm&apos;)</deletedAxiom>
<deletedAxiom>&apos;cytoplasmic transcription factor complex&apos; SubClassOf &apos;part of&apos; some &apos;cytoplasm&apos;</deletedAxiom>
<deletedAxiom>&apos;cytoplasmic transcription factor complex&apos; SubClassOf &apos;transcription factor complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_81524</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_81524 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_328432</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_328432 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005070</classIRI>
<classLabel>SH3/SH2 adaptor activity</classLabel>
<deletedAxiom>&apos;SH3/SH2 adaptor activity&apos; SubClassOf &apos;signaling adaptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005072</classIRI>
<classLabel>transforming growth factor beta receptor, cytoplasmic mediator activity</classLabel>
<deletedAxiom>&apos;transforming growth factor beta receptor, cytoplasmic mediator activity&apos; SubClassOf &apos;molecular transducer activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_46613</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_46613 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010964</classIRI>
<classLabel>regulation of chromatin silencing by small RNA</classLabel>
<deletedAxiom>&apos;regulation of chromatin silencing by small RNA&apos; SubClassOf &apos;regulation of gene silencing by RNA&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of chromatin silencing by small RNA&apos; SubClassOf &apos;regulation of chromatin silencing&apos;</deletedAxiom>
<newAxiom>&apos;regulation of chromatin silencing by small RNA&apos; SubClassOf &apos;regulation of heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_931223</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_931223 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_206350</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_206350 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007225</classIRI>
<classLabel>patched ligand maturation</classLabel>
<deletedAxiom>&apos;patched ligand maturation&apos; SubClassOf &apos;part of&apos; some &apos;positive regulation of smoothened signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;patched ligand maturation&apos; SubClassOf &apos;signal maturation&apos;</deletedAxiom>
<deletedAxiom>&apos;patched ligand maturation&apos; SubClassOf &apos;protein maturation&apos;</deletedAxiom>
<newAxiom>&apos;patched ligand maturation&apos; SubClassOf &apos;peptide hormone processing&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071789</classIRI>
<classLabel>spindle pole body localization to nuclear envelope</classLabel>
<deletedAxiom>&apos;spindle pole body localization to nuclear envelope&apos; EquivalentTo &apos;spindle pole body localization&apos; and (&apos;has target end location&apos; some &apos;nuclear envelope&apos;)</deletedAxiom>
<deletedAxiom>&apos;spindle pole body localization to nuclear envelope&apos; SubClassOf &apos;has target end location&apos; some &apos;nuclear envelope&apos;</deletedAxiom>
<deletedAxiom>&apos;spindle pole body localization to nuclear envelope&apos; SubClassOf &apos;spindle pole body localization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071790</classIRI>
<classLabel>establishment of spindle pole body localization to nuclear envelope</classLabel>
<deletedAxiom>&apos;establishment of spindle pole body localization to nuclear envelope&apos; SubClassOf &apos;establishment of spindle pole body localization&apos;</deletedAxiom>
<deletedAxiom>&apos;establishment of spindle pole body localization to nuclear envelope&apos; SubClassOf &apos;spindle pole body localization to nuclear envelope&apos;</deletedAxiom>
<deletedAxiom>&apos;establishment of spindle pole body localization to nuclear envelope&apos; EquivalentTo &apos;establishment of spindle pole body localization&apos; and (&apos;has target end location&apos; some &apos;nuclear envelope&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071629</classIRI>
<classLabel>cytoplasm protein quality control by the ubiquitin-proteasome system</classLabel>
<deletedAxiom>&apos;cytoplasm protein quality control by the ubiquitin-proteasome system&apos; SubClassOf &apos;protein quality control for misfolded or incompletely synthesized proteins&apos;</deletedAxiom>
<newAxiom>&apos;cytoplasm protein quality control by the ubiquitin-proteasome system&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140455</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_11613</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_11613 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_11604</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_11604 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_11608</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_11608 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_11593</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_11593 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_11592</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_11592 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_11571</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_11571 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_5285</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_5285 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007016</classIRI>
<classLabel>cytoskeletal anchoring at plasma membrane</classLabel>
<deletedAxiom>&apos;cytoskeletal anchoring at plasma membrane&apos; SubClassOf &apos;maintenance of protein location in cell&apos;</deletedAxiom>
<deletedAxiom>&apos;cytoskeletal anchoring at plasma membrane&apos; SubClassOf &apos;cytoskeleton organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_11595</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_11595 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_11599</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_11599 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_11598</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_11598 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_255725</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_255725 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061837</classIRI>
<classLabel>neuropeptide processing</classLabel>
<deletedAxiom>&apos;neuropeptide processing&apos; SubClassOf &apos;protein processing&apos;</deletedAxiom>
<newAxiom>&apos;neuropeptide processing&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140448</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_108599</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_108599 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071144</classIRI>
<classLabel>heteromeric SMAD protein complex</classLabel>
<newAxiom>&apos;heteromeric SMAD protein complex&apos; SubClassOf &apos;part of&apos; some &apos;nucleus&apos;</newAxiom>
<newAxiom>&apos;heteromeric SMAD protein complex&apos; SubClassOf &apos;capable of&apos; some &apos;DNA-binding transcription factor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061746</classIRI>
<classLabel>single-stranded DNA-dependent GTPase activity</classLabel>
<deletedAxiom>&apos;single-stranded DNA-dependent GTPase activity&apos; SubClassOf &apos;GTPase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061793</classIRI>
<classLabel>chromatin lock complex</classLabel>
<deletedAxiom>&apos;chromatin lock complex&apos; SubClassOf &apos;capable of part of&apos; some &apos;heterochromatin assembly involved in chromatin silencing&apos;</deletedAxiom>
<newAxiom>&apos;chromatin lock complex&apos; SubClassOf &apos;capable of part of&apos; some &apos;heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_11207</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_11207 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_745407</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_745407 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036411</classIRI>
<classLabel>H-NS-Cnu complex</classLabel>
<deletedAxiom>&apos;H-NS-Cnu complex&apos; SubClassOf &apos;part of&apos; some &apos;cytosol&apos;</deletedAxiom>
<deletedAxiom>&apos;H-NS-Cnu complex&apos; SubClassOf &apos;cytoplasmic transcriptional repressor complex&apos;</deletedAxiom>
<newAxiom>&apos;H-NS-Cnu complex&apos; SubClassOf &apos;transcriptional repressor complex&apos;</newAxiom>
<newAxiom>&apos;H-NS-Cnu complex&apos; SubClassOf &apos;in taxon&apos; only &apos;Bacteria&apos;</newAxiom>
<newAxiom>&apos;H-NS-Cnu complex&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Bacteria&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_50372</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_50372 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_118267</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_118267 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_1380774</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_1380774 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061187</classIRI>
<classLabel>regulation of chromatin silencing at rDNA</classLabel>
<deletedAxiom>&apos;regulation of chromatin silencing at rDNA&apos; SubClassOf &apos;regulation of chromatin silencing&apos;</deletedAxiom>
<newAxiom>&apos;regulation of chromatin silencing at rDNA&apos; SubClassOf &apos;regulation of heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061186</classIRI>
<classLabel>negative regulation of chromatin silencing at silent mating-type cassette</classLabel>
<deletedAxiom>&apos;negative regulation of chromatin silencing at silent mating-type cassette&apos; SubClassOf &apos;negative regulation of chromatin silencing&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of chromatin silencing at silent mating-type cassette&apos; SubClassOf &apos;negative regulation of heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061188</classIRI>
<classLabel>negative regulation of chromatin silencing at rDNA</classLabel>
<deletedAxiom>&apos;negative regulation of chromatin silencing at rDNA&apos; SubClassOf &apos;negative regulation of chromatin silencing&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of chromatin silencing at rDNA&apos; SubClassOf &apos;negative regulation of heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_867696</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_867696 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_5313</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_5313 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051643</classIRI>
<classLabel>endoplasmic reticulum localization</classLabel>
<newAxiom>&apos;endoplasmic reticulum localization&apos; SubClassOf &apos;part of&apos; some &apos;endoplasmic reticulum organization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_5654</classIRI>
<classLabel>Trypanosomatidae</classLabel>
<deletedAxiom>&apos;Trypanosomatidae&apos; SubClassOf &apos;Kinetoplastida&apos;</deletedAxiom>
<newAxiom>&apos;Trypanosomatidae&apos; SubClassOf http://purl.obolibrary.org/obo/NCBITaxon_2704949</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_554915</classIRI>
<classLabel>Amoebozoa</classLabel>
<deletedAxiom>&apos;Euglenozoa&apos; DisjointWith &apos;Amoebozoa&apos;</deletedAxiom>
<deletedAxiom>&apos;Stramenopiles&apos; DisjointWith &apos;Amoebozoa&apos;</deletedAxiom>
<deletedAxiom>&apos;Alveolata&apos; DisjointWith &apos;Amoebozoa&apos;</deletedAxiom>
<deletedAxiom>&apos;Fornicata&apos; DisjointWith &apos;Amoebozoa&apos;</deletedAxiom>
<newAxiom>http://purl.obolibrary.org/obo/NCBITaxon_2611352 DisjointWith &apos;Amoebozoa&apos;</newAxiom>
<newAxiom>http://purl.obolibrary.org/obo/NCBITaxon_2698737 DisjointWith &apos;Amoebozoa&apos;</newAxiom>
<newAxiom>http://purl.obolibrary.org/obo/NCBITaxon_2611341 DisjointWith &apos;Amoebozoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_5532</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_5532 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_310748</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_310748 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075344</classIRI>
<classLabel>modulation by symbiont of host protein levels</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host protein levels&apos; SubClassOf &apos;modulation of process of other organism involved in symbiotic interaction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110129</classIRI>
<classLabel>SHREC2 complex</classLabel>
<deletedAxiom>&apos;SHREC2 complex&apos; SubClassOf &apos;nuclear transcriptional repressor complex&apos;</deletedAxiom>
<newAxiom>&apos;SHREC2 complex&apos; SubClassOf &apos;transcriptional repressor complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_143961</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_143961 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903213</classIRI>
<classLabel>protein localization to subtelomeric heterochromatin</classLabel>
<newAxiom>&apos;protein localization to subtelomeric heterochromatin&apos; SubClassOf &apos;protein localization to chromosome, telomeric region&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110001</classIRI>
<classLabel>toxin-antitoxin complex</classLabel>
<deletedAxiom>&apos;toxin-antitoxin complex&apos; SubClassOf &apos;transcription factor complex&apos;</deletedAxiom>
<deletedAxiom>&apos;toxin-antitoxin complex&apos; SubClassOf &apos;capable of&apos; some &apos;DNA-binding transcription repressor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099115</classIRI>
<classLabel>chromosome, subtelomeric region</classLabel>
<deletedAxiom>&apos;chromosome, subtelomeric region&apos; SubClassOf &apos;chromosomal region&apos;</deletedAxiom>
<newAxiom>&apos;chromosome, subtelomeric region&apos; SubClassOf &apos;chromosome, telomeric region&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099114</classIRI>
<classLabel>chromatin silencing at subtelomere</classLabel>
<deletedAxiom>&apos;chromatin silencing at subtelomere&apos; SubClassOf &apos;chromatin silencing&apos;</deletedAxiom>
<newAxiom>&apos;chromatin silencing at subtelomere&apos; SubClassOf &apos;chromatin silencing at telomere&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099053</classIRI>
<classLabel>activating signal cointegrator 1 complex</classLabel>
<deletedAxiom>&apos;activating signal cointegrator 1 complex&apos; SubClassOf &apos;protein-containing complex&apos;</deletedAxiom>
<newAxiom>&apos;activating signal cointegrator 1 complex&apos; SubClassOf &apos;RNA polymerase II transcription factor complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090578</classIRI>
<classLabel>RNA polymerase V transcription factor complex</classLabel>
<deletedAxiom>&apos;RNA polymerase V transcription factor complex&apos; SubClassOf &apos;nuclear transcription factor complex&apos;</deletedAxiom>
<deletedAxiom>&apos;RNA polymerase V transcription factor complex&apos; SubClassOf &apos;capable of&apos; some &apos;regulation of transcription by RNA polymerase V&apos;</deletedAxiom>
<deletedAxiom>&apos;RNA polymerase V transcription factor complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;capable of&apos; some &apos;regulation of transcription by RNA polymerase V&apos;)</deletedAxiom>
<newAxiom>&apos;RNA polymerase V transcription factor complex&apos; SubClassOf &apos;transcription factor complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090577</classIRI>
<classLabel>RNA polymerase IV transcription factor complex</classLabel>
<deletedAxiom>&apos;RNA polymerase IV transcription factor complex&apos; SubClassOf &apos;nuclear transcription factor complex&apos;</deletedAxiom>
<newAxiom>&apos;RNA polymerase IV transcription factor complex&apos; SubClassOf &apos;transcription factor complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090574</classIRI>
<classLabel>RNA polymerase V transcription repressor complex</classLabel>
<deletedAxiom>&apos;RNA polymerase V transcription repressor complex&apos; SubClassOf &apos;nuclear transcriptional repressor complex&apos;</deletedAxiom>
<newAxiom>&apos;RNA polymerase V transcription repressor complex&apos; SubClassOf &apos;transcriptional repressor complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090573</classIRI>
<classLabel>RNA polymerase IV transcription repressor complex</classLabel>
<deletedAxiom>&apos;RNA polymerase IV transcription repressor complex&apos; SubClassOf &apos;nuclear transcriptional repressor complex&apos;</deletedAxiom>
<newAxiom>&apos;RNA polymerase IV transcription repressor complex&apos; SubClassOf &apos;transcriptional repressor complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090576</classIRI>
<classLabel>RNA polymerase III transcription factor complex</classLabel>
<deletedAxiom>&apos;RNA polymerase III transcription factor complex&apos; SubClassOf &apos;nuclear transcription factor complex&apos;</deletedAxiom>
<deletedAxiom>&apos;RNA polymerase III transcription factor complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;capable of&apos; some &apos;regulation of transcription by RNA polymerase III&apos;)</deletedAxiom>
<deletedAxiom>&apos;RNA polymerase III transcription factor complex&apos; SubClassOf &apos;capable of&apos; some &apos;regulation of transcription by RNA polymerase III&apos;</deletedAxiom>
<newAxiom>&apos;RNA polymerase III transcription factor complex&apos; SubClassOf &apos;transcription factor complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090575</classIRI>
<classLabel>RNA polymerase II transcription factor complex</classLabel>
<deletedAxiom>&apos;RNA polymerase II transcription factor complex&apos; SubClassOf &apos;nuclear transcription factor complex&apos;</deletedAxiom>
<deletedAxiom>&apos;RNA polymerase II transcription factor complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;capable of&apos; some &apos;regulation of transcription by RNA polymerase II&apos;)</deletedAxiom>
<deletedAxiom>&apos;RNA polymerase II transcription factor complex&apos; SubClassOf &apos;capable of&apos; some &apos;regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
<newAxiom>&apos;RNA polymerase II transcription factor complex&apos; SubClassOf &apos;transcription factor complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090570</classIRI>
<classLabel>RNA polymerase I transcription repressor complex</classLabel>
<deletedAxiom>&apos;RNA polymerase I transcription repressor complex&apos; SubClassOf &apos;nuclear transcriptional repressor complex&apos;</deletedAxiom>
<newAxiom>&apos;RNA polymerase I transcription repressor complex&apos; SubClassOf &apos;transcriptional repressor complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090572</classIRI>
<classLabel>RNA polymerase III transcription repressor complex</classLabel>
<deletedAxiom>&apos;RNA polymerase III transcription repressor complex&apos; SubClassOf &apos;nuclear transcriptional repressor complex&apos;</deletedAxiom>
<newAxiom>&apos;RNA polymerase III transcription repressor complex&apos; SubClassOf &apos;transcriptional repressor complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090571</classIRI>
<classLabel>RNA polymerase II transcription repressor complex</classLabel>
<deletedAxiom>&apos;RNA polymerase II transcription repressor complex&apos; SubClassOf &apos;nuclear transcriptional repressor complex&apos;</deletedAxiom>
<newAxiom>&apos;RNA polymerase II transcription repressor complex&apos; SubClassOf &apos;transcriptional repressor complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090569</classIRI>
<classLabel>cytoplasmic transcriptional repressor complex</classLabel>
<deletedAxiom>&apos;cytoplasmic transcriptional repressor complex&apos; EquivalentTo &apos;transcriptional repressor complex&apos; and (&apos;part of&apos; some &apos;cytoplasm&apos;)</deletedAxiom>
<deletedAxiom>&apos;cytoplasmic transcriptional repressor complex&apos; SubClassOf &apos;transcriptional repressor complex&apos;</deletedAxiom>
<deletedAxiom>&apos;cytoplasmic transcriptional repressor complex&apos; SubClassOf &apos;part of&apos; some &apos;cytoplasm&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090568</classIRI>
<classLabel>nuclear transcriptional repressor complex</classLabel>
<deletedAxiom>&apos;nuclear transcriptional repressor complex&apos; SubClassOf &apos;part of&apos; some &apos;nucleoplasm&apos;</deletedAxiom>
<deletedAxiom>&apos;nuclear transcriptional repressor complex&apos; SubClassOf &apos;transcriptional repressor complex&apos;</deletedAxiom>
<deletedAxiom>&apos;nuclear transcriptional repressor complex&apos; EquivalentTo &apos;transcriptional repressor complex&apos; and (&apos;part of&apos; some &apos;nucleus&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903539</classIRI>
<classLabel>protein localization to postsynaptic membrane</classLabel>
<deletedAxiom>&apos;protein localization to postsynaptic membrane&apos; SubClassOf &apos;protein localization to synapse&apos;</deletedAxiom>
<newAxiom>&apos;protein localization to postsynaptic membrane&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0062237</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016581</classIRI>
<classLabel>NuRD complex</classLabel>
<deletedAxiom>&apos;NuRD complex&apos; SubClassOf &apos;nuclear transcriptional repressor complex&apos;</deletedAxiom>
<newAxiom>&apos;NuRD complex&apos; SubClassOf &apos;transcriptional repressor complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016441</classIRI>
<classLabel>posttranscriptional gene silencing</classLabel>
<deletedAxiom>&apos;posttranscriptional gene silencing&apos; SubClassOf &apos;gene silencing&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016486</classIRI>
<classLabel>peptide hormone processing</classLabel>
<deletedAxiom>&apos;peptide hormone processing&apos; SubClassOf &apos;protein processing&apos;</deletedAxiom>
<newAxiom>&apos;peptide hormone processing&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140448</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903865</classIRI>
<classLabel>sigma factor antagonist complex</classLabel>
<deletedAxiom>&apos;sigma factor antagonist complex&apos; SubClassOf &apos;transcriptional repressor complex&apos;</deletedAxiom>
<newAxiom>&apos;sigma factor antagonist complex&apos; SubClassOf &apos;transcription factor complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031933</classIRI>
<classLabel>telomeric heterochromatin</classLabel>
<deletedAxiom>&apos;telomeric heterochromatin&apos; SubClassOf &apos;part of&apos; some &apos;chromosome, telomeric region&apos;</deletedAxiom>
<deletedAxiom>&apos;telomeric heterochromatin&apos; EquivalentTo &apos;heterochromatin&apos; and (&apos;part of&apos; some &apos;chromosome, telomeric region&apos;)</deletedAxiom>
<deletedAxiom>&apos;telomeric heterochromatin&apos; SubClassOf &apos;heterochromatin&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090310</classIRI>
<classLabel>negative regulation of DNA methylation-dependent heterochromatin assembly</classLabel>
<deletedAxiom>&apos;negative regulation of DNA methylation-dependent heterochromatin assembly&apos; SubClassOf &apos;negative regulation of chromatin silencing&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of DNA methylation-dependent heterochromatin assembly&apos; SubClassOf &apos;negative regulation of heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090309</classIRI>
<classLabel>positive regulation of DNA methylation-dependent heterochromatin assembly</classLabel>
<deletedAxiom>&apos;positive regulation of DNA methylation-dependent heterochromatin assembly&apos; SubClassOf &apos;positive regulation of chromatin silencing&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of DNA methylation-dependent heterochromatin assembly&apos; SubClassOf &apos;positive regulation of heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090308</classIRI>
<classLabel>regulation of DNA methylation-dependent heterochromatin assembly</classLabel>
<deletedAxiom>&apos;regulation of DNA methylation-dependent heterochromatin assembly&apos; SubClassOf &apos;regulation of chromatin silencing&apos;</deletedAxiom>
<newAxiom>&apos;regulation of DNA methylation-dependent heterochromatin assembly&apos; SubClassOf &apos;regulation of heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_1221</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_1221 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_1212</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_1212 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_1217</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_1217 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090211</classIRI>
<classLabel>positive regulation of establishment of blood-brain barrier</classLabel>
<newAxiom>&apos;positive regulation of establishment of blood-brain barrier&apos; SubClassOf &apos;positive regulation of nervous system development&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090210</classIRI>
<classLabel>regulation of establishment of blood-brain barrier</classLabel>
<newAxiom>&apos;regulation of establishment of blood-brain barrier&apos; SubClassOf &apos;regulation of nervous system development&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090212</classIRI>
<classLabel>negative regulation of establishment of blood-brain barrier</classLabel>
<newAxiom>&apos;negative regulation of establishment of blood-brain barrier&apos; SubClassOf &apos;negative regulation of nervous system development&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090286</classIRI>
<classLabel>cytoskeletal anchoring at nuclear membrane</classLabel>
<deletedAxiom>&apos;cytoskeletal anchoring at nuclear membrane&apos; SubClassOf &apos;maintenance of protein location in cell&apos;</deletedAxiom>
<deletedAxiom>&apos;cytoskeletal anchoring at nuclear membrane&apos; SubClassOf &apos;cytoskeleton organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_1172</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_1172 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_89013</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_89013 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090115</classIRI>
<classLabel>C-5 methylation on cytosine involved in chromatin silencing</classLabel>
<deletedAxiom>&apos;C-5 methylation on cytosine involved in chromatin silencing&apos; SubClassOf &apos;C-5 methylation of cytosine&apos;</deletedAxiom>
<deletedAxiom>&apos;C-5 methylation on cytosine involved in chromatin silencing&apos; SubClassOf &apos;part of&apos; some &apos;DNA methylation-dependent heterochromatin assembly&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090053</classIRI>
<classLabel>positive regulation of chromatin silencing at centromere</classLabel>
<deletedAxiom>&apos;positive regulation of chromatin silencing at centromere&apos; SubClassOf &apos;positive regulation of chromatin silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of chromatin silencing at centromere&apos; SubClassOf &apos;positively regulates&apos; some &apos;chromatin silencing at centromere&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of chromatin silencing at centromere&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;chromatin silencing at centromere&apos;)</deletedAxiom>
<newAxiom>&apos;positive regulation of chromatin silencing at centromere&apos; SubClassOf &apos;positively regulates&apos; some &apos;pericentric heterochromatin assembly&apos;</newAxiom>
<newAxiom>&apos;positive regulation of chromatin silencing at centromere&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;pericentric heterochromatin assembly&apos;)</newAxiom>
<newAxiom>&apos;positive regulation of chromatin silencing at centromere&apos; SubClassOf &apos;positive regulation of heterochromatin assembly&apos;</newAxiom>
<newAxiom>&apos;positive regulation of chromatin silencing at centromere&apos; SubClassOf &apos;positive regulation of protein-containing complex assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090052</classIRI>
<classLabel>regulation of chromatin silencing at centromere</classLabel>
<deletedAxiom>&apos;regulation of chromatin silencing at centromere&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;chromatin silencing at centromere&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of chromatin silencing at centromere&apos; SubClassOf &apos;regulation of chromatin silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of chromatin silencing at centromere&apos; SubClassOf &apos;regulates&apos; some &apos;chromatin silencing at centromere&apos;</deletedAxiom>
<newAxiom>&apos;regulation of chromatin silencing at centromere&apos; SubClassOf &apos;regulation of centromere complex assembly&apos;</newAxiom>
<newAxiom>&apos;regulation of chromatin silencing at centromere&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;pericentric heterochromatin assembly&apos;)</newAxiom>
<newAxiom>&apos;regulation of chromatin silencing at centromere&apos; SubClassOf &apos;regulation of heterochromatin assembly&apos;</newAxiom>
<newAxiom>&apos;regulation of chromatin silencing at centromere&apos; SubClassOf &apos;regulates&apos; some &apos;pericentric heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090055</classIRI>
<classLabel>positive regulation of chromatin silencing at silent mating-type cassette</classLabel>
<deletedAxiom>&apos;positive regulation of chromatin silencing at silent mating-type cassette&apos; SubClassOf &apos;positive regulation of chromatin silencing&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of chromatin silencing at silent mating-type cassette&apos; SubClassOf &apos;positive regulation of heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090054</classIRI>
<classLabel>regulation of chromatin silencing at silent mating-type cassette</classLabel>
<deletedAxiom>&apos;regulation of chromatin silencing at silent mating-type cassette&apos; SubClassOf &apos;regulation of chromatin silencing&apos;</deletedAxiom>
<newAxiom>&apos;regulation of chromatin silencing at silent mating-type cassette&apos; SubClassOf &apos;regulation of heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031508</classIRI>
<classLabel>pericentric heterochromatin assembly</classLabel>
<newAxiom>&apos;pericentric heterochromatin assembly&apos; SubClassOf &apos;negative regulation of gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031507</classIRI>
<classLabel>heterochromatin assembly</classLabel>
<deletedAxiom>&apos;heterochromatin assembly&apos; SubClassOf &apos;heterochromatin organization&apos;</deletedAxiom>
<deletedAxiom>&apos;heterochromatin assembly&apos; EquivalentTo &apos;cellular process&apos; and (&apos;results in assembly of&apos; some &apos;heterochromatin&apos;)</deletedAxiom>
<newAxiom>&apos;heterochromatin assembly&apos; SubClassOf &apos;chromosome organization&apos;</newAxiom>
<newAxiom>&apos;heterochromatin assembly&apos; EquivalentTo &apos;chromatin remodeling&apos; and (&apos;results in assembly of&apos; some &apos;heterochromatin&apos;)</newAxiom>
<newAxiom>&apos;heterochromatin assembly&apos; SubClassOf &apos;heterochromatin organization involved in chromatin silencing&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031509</classIRI>
<classLabel>telomeric heterochromatin assembly</classLabel>
<deletedAxiom>&apos;telomeric heterochromatin assembly&apos; SubClassOf &apos;results in assembly of&apos; some &apos;telomeric heterochromatin&apos;</deletedAxiom>
<deletedAxiom>&apos;telomeric heterochromatin assembly&apos; SubClassOf &apos;heterochromatin assembly&apos;</deletedAxiom>
<deletedAxiom>&apos;telomeric heterochromatin assembly&apos; EquivalentTo &apos;cellular component assembly&apos; and (&apos;results in assembly of&apos; some &apos;telomeric heterochromatin&apos;)</deletedAxiom>
<newAxiom>&apos;telomeric heterochromatin assembly&apos; EquivalentTo &apos;cellular component assembly&apos; and (&apos;results in assembly of&apos; some &apos;nuclear subtelomeric heterochromatin&apos;)</newAxiom>
<newAxiom>&apos;telomeric heterochromatin assembly&apos; SubClassOf &apos;chromatin assembly&apos;</newAxiom>
<newAxiom>&apos;telomeric heterochromatin assembly&apos; SubClassOf &apos;telomere assembly&apos;</newAxiom>
<newAxiom>&apos;telomeric heterochromatin assembly&apos; SubClassOf &apos;heterochromatin organization&apos;</newAxiom>
<newAxiom>&apos;telomeric heterochromatin assembly&apos; SubClassOf &apos;results in assembly of&apos; some &apos;nuclear subtelomeric heterochromatin&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_1033979</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_1033979 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_427699</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_427699 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031445</classIRI>
<classLabel>regulation of heterochromatin assembly</classLabel>
<newAxiom>&apos;regulation of heterochromatin assembly&apos; SubClassOf &apos;regulation of chromatin silencing&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031452</classIRI>
<classLabel>negative regulation of heterochromatin assembly</classLabel>
<newAxiom>&apos;negative regulation of heterochromatin assembly&apos; SubClassOf &apos;negative regulation of chromatin silencing&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031453</classIRI>
<classLabel>positive regulation of heterochromatin assembly</classLabel>
<newAxiom>&apos;positive regulation of heterochromatin assembly&apos; SubClassOf &apos;positive regulation of chromatin silencing&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_207245</classIRI>
<classLabel>Fornicata</classLabel>
<deletedAxiom>&apos;Fornicata&apos; DisjointWith &apos;Alveolata&apos;</deletedAxiom>
<deletedAxiom>&apos;Fornicata&apos; DisjointWith &apos;Stramenopiles&apos;</deletedAxiom>
<deletedAxiom>&apos;Fornicata&apos; DisjointWith &apos;Cryptophyta&apos;</deletedAxiom>
<deletedAxiom>&apos;Fornicata&apos; DisjointWith &apos;Viridiplantae&apos;</deletedAxiom>
<deletedAxiom>&apos;Fornicata&apos; DisjointWith &apos;Opisthokonta&apos;</deletedAxiom>
<deletedAxiom>&apos;Fornicata&apos; DisjointWith &apos;Euglenozoa&apos;</deletedAxiom>
<deletedAxiom>&apos;Fornicata&apos; SubClassOf &apos;Eukaryota&apos;</deletedAxiom>
<deletedAxiom>&apos;Fornicata&apos; DisjointWith &apos;Glaucocystophyceae&apos;</deletedAxiom>
<deletedAxiom>&apos;Fornicata&apos; DisjointWith &apos;Amoebozoa&apos;</deletedAxiom>
<newAxiom>&apos;Fornicata&apos; SubClassOf http://purl.obolibrary.org/obo/NCBITaxon_2611341</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006344</classIRI>
<classLabel>maintenance of chromatin silencing</classLabel>
<deletedAxiom>&apos;maintenance of chromatin silencing&apos; SubClassOf &apos;part of&apos; some &apos;chromatin silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;maintenance of chromatin silencing&apos; SubClassOf &apos;chromosome organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006343</classIRI>
<classLabel>establishment of chromatin silencing</classLabel>
<deletedAxiom>&apos;establishment of chromatin silencing&apos; SubClassOf &apos;part of&apos; some &apos;chromatin silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;establishment of chromatin silencing&apos; SubClassOf &apos;chromosome organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006346</classIRI>
<classLabel>DNA methylation-dependent heterochromatin assembly</classLabel>
<deletedAxiom>&apos;DNA methylation-dependent heterochromatin assembly&apos; SubClassOf &apos;chromatin silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;DNA methylation-dependent heterochromatin assembly&apos; EquivalentTo &apos;chromatin silencing&apos; and (&apos;has_part&apos; some &apos;DNA methylation&apos;)</deletedAxiom>
<newAxiom>&apos;DNA methylation-dependent heterochromatin assembly&apos; SubClassOf &apos;heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070921</classIRI>
<classLabel>regulation of production of siRNA involved in chromatin silencing by small RNA</classLabel>
<deletedAxiom>&apos;regulation of production of siRNA involved in chromatin silencing by small RNA&apos; SubClassOf &apos;regulation of chromatin silencing by small RNA&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of production of siRNA involved in chromatin silencing by small RNA&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;production of siRNA involved in chromatin silencing by small RNA&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of production of siRNA involved in chromatin silencing by small RNA&apos; SubClassOf &apos;regulates&apos; some &apos;production of siRNA involved in chromatin silencing by small RNA&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070924</classIRI>
<classLabel>heterochromatin assembly involved in chromatin silencing by small RNA</classLabel>
<deletedAxiom>&apos;heterochromatin assembly involved in chromatin silencing by small RNA&apos; SubClassOf &apos;part of&apos; some &apos;chromatin silencing by small RNA&apos;</deletedAxiom>
<deletedAxiom>&apos;heterochromatin assembly involved in chromatin silencing by small RNA&apos; SubClassOf &apos;heterochromatin assembly involved in chromatin silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;heterochromatin assembly involved in chromatin silencing by small RNA&apos; EquivalentTo &apos;heterochromatin assembly&apos; and (&apos;part of&apos; some &apos;chromatin silencing by small RNA&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070870</classIRI>
<classLabel>heterochromatin maintenance involved in chromatin silencing</classLabel>
<deletedAxiom>&apos;heterochromatin maintenance involved in chromatin silencing&apos; EquivalentTo &apos;heterochromatin maintenance&apos; and (&apos;part of&apos; some &apos;chromatin silencing&apos;)</deletedAxiom>
<deletedAxiom>&apos;heterochromatin maintenance involved in chromatin silencing&apos; SubClassOf &apos;heterochromatin organization involved in chromatin silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;heterochromatin maintenance involved in chromatin silencing&apos; SubClassOf &apos;heterochromatin maintenance&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070869</classIRI>
<classLabel>heterochromatin assembly involved in chromatin silencing</classLabel>
<deletedAxiom>&apos;heterochromatin assembly involved in chromatin silencing&apos; SubClassOf &apos;heterochromatin organization involved in chromatin silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;heterochromatin assembly involved in chromatin silencing&apos; EquivalentTo &apos;heterochromatin assembly&apos; and (&apos;part of&apos; some &apos;chromatin silencing&apos;)</deletedAxiom>
<deletedAxiom>&apos;heterochromatin assembly involved in chromatin silencing&apos; SubClassOf &apos;heterochromatin assembly&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070847</classIRI>
<classLabel>core mediator complex</classLabel>
<newAxiom>&apos;core mediator complex&apos; SubClassOf &apos;part of&apos; some &apos;nucleus&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_60888</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_60888 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070824</classIRI>
<classLabel>SHREC complex</classLabel>
<deletedAxiom>&apos;SHREC complex&apos; SubClassOf &apos;nuclear transcriptional repressor complex&apos;</deletedAxiom>
<newAxiom>&apos;SHREC complex&apos; SubClassOf &apos;transcriptional repressor complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070829</classIRI>
<classLabel>heterochromatin maintenance</classLabel>
<deletedAxiom>&apos;heterochromatin maintenance&apos; SubClassOf &apos;heterochromatin organization&apos;</deletedAxiom>
<newAxiom>&apos;heterochromatin maintenance&apos; SubClassOf &apos;chromosome organization&apos;</newAxiom>
<newAxiom>&apos;heterochromatin maintenance&apos; SubClassOf &apos;heterochromatin organization involved in chromatin silencing&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070632</classIRI>
<classLabel>establishment of spindle pole body localization</classLabel>
<deletedAxiom>&apos;establishment of spindle pole body localization&apos; SubClassOf &apos;establishment of localization in cell&apos;</deletedAxiom>
<deletedAxiom>&apos;establishment of spindle pole body localization&apos; SubClassOf &apos;spindle pole body localization&apos;</deletedAxiom>
<deletedAxiom>&apos;establishment of spindle pole body localization&apos; EquivalentTo &apos;establishment of localization&apos; and (&apos;transports or maintains localization of&apos; some &apos;spindle pole body&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031048</classIRI>
<classLabel>chromatin silencing by small RNA</classLabel>
<deletedAxiom>&apos;chromatin silencing by small RNA&apos; SubClassOf &apos;process has causal agent&apos; some &apos;snRNA&apos;</deletedAxiom>
<deletedAxiom>&apos;chromatin silencing by small RNA&apos; SubClassOf &apos;chromatin silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;chromatin silencing by small RNA&apos; SubClassOf &apos;gene silencing by RNA&apos;</deletedAxiom>
<deletedAxiom>&apos;chromatin silencing by small RNA&apos; EquivalentTo &apos;chromatin silencing&apos; and (&apos;process has causal agent&apos; some &apos;snRNA&apos;)</deletedAxiom>
<newAxiom>&apos;chromatin silencing by small RNA&apos; SubClassOf &apos;heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_58022</classIRI>
<classLabel>Gnetophyta</classLabel>
<deletedAxiom>&apos;Gnetidae&apos; DisjointWith &apos;Gnetophyta&apos;</deletedAxiom>
<newAxiom>http://purl.obolibrary.org/obo/NCBITaxon_3372 DisjointWith &apos;Gnetophyta&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047992</classIRI>
<classLabel>hydroxylysine kinase activity</classLabel>
<deletedAxiom>&apos;hydroxylysine kinase activity&apos; SubClassOf &apos;kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;hydroxylysine kinase activity&apos; SubClassOf &apos;amino acid kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_83233</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_83233 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_83234</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_83234 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_83344</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_83344 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_34383</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_34383 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_34380</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_34380 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106084</classIRI>
<classLabel>nuclear membrane mitotic spindle pole body tethering complex</classLabel>
<deletedAxiom>&apos;nuclear membrane mitotic spindle pole body tethering complex&apos; SubClassOf &apos;capable of part of&apos; some &apos;spindle pole body localization to nuclear envelope&apos;</deletedAxiom>
<newAxiom>&apos;nuclear membrane mitotic spindle pole body tethering complex&apos; SubClassOf &apos;capable of part of&apos; some &apos;mitotic spindle pole body localization to nuclear envelope&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_311413</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_311413 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_38254</classIRI>
<classLabel>Glaucocystophyceae</classLabel>
<deletedAxiom>&apos;Stramenopiles&apos; DisjointWith &apos;Glaucocystophyceae&apos;</deletedAxiom>
<deletedAxiom>&apos;Alveolata&apos; DisjointWith &apos;Glaucocystophyceae&apos;</deletedAxiom>
<deletedAxiom>&apos;Euglenozoa&apos; DisjointWith &apos;Glaucocystophyceae&apos;</deletedAxiom>
<deletedAxiom>&apos;Fornicata&apos; DisjointWith &apos;Glaucocystophyceae&apos;</deletedAxiom>
<newAxiom>http://purl.obolibrary.org/obo/NCBITaxon_2611341 DisjointWith &apos;Glaucocystophyceae&apos;</newAxiom>
<newAxiom>http://purl.obolibrary.org/obo/NCBITaxon_2611352 DisjointWith &apos;Glaucocystophyceae&apos;</newAxiom>
<newAxiom>http://purl.obolibrary.org/obo/NCBITaxon_2698737 DisjointWith &apos;Glaucocystophyceae&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_1198989</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_1198989 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903000</classIRI>
<classLabel>regulation of lipid transport across blood-brain barrier</classLabel>
<newAxiom>&apos;regulation of lipid transport across blood-brain barrier&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0150200</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903002</classIRI>
<classLabel>positive regulation of lipid transport across blood-brain barrier</classLabel>
<newAxiom>&apos;positive regulation of lipid transport across blood-brain barrier&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0150201</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903001</classIRI>
<classLabel>negative regulation of lipid transport across blood-brain barrier</classLabel>
<newAxiom>&apos;negative regulation of lipid transport across blood-brain barrier&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0150202</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062198</classIRI>
<classLabel>rDNA replication pause site heterochromatin</classLabel>
<deletedAxiom>&apos;rDNA replication pause site heterochromatin&apos; EquivalentTo &apos;chromosomal region&apos; and (&apos;coincident with&apos; some &apos;rDNA_replication_fork_barrier&apos;)</deletedAxiom>
<deletedAxiom>&apos;rDNA replication pause site heterochromatin&apos; SubClassOf &apos;coincident with&apos; some &apos;rDNA_replication_fork_barrier&apos;</deletedAxiom>
<deletedAxiom>&apos;rDNA replication pause site heterochromatin&apos; SubClassOf &apos;chromosomal region&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990433</classIRI>
<classLabel>CSL-Notch-Mastermind transcription factor complex</classLabel>
<newAxiom>&apos;CSL-Notch-Mastermind transcription factor complex&apos; SubClassOf &apos;capable of&apos; some &apos;DNA-binding transcription factor activity&apos;</newAxiom>
<newAxiom>&apos;CSL-Notch-Mastermind transcription factor complex&apos; SubClassOf &apos;part of&apos; some &apos;nucleus&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_213423</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_213423 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990513</classIRI>
<classLabel>CLOCK-BMAL transcription complex</classLabel>
<newAxiom>&apos;CLOCK-BMAL transcription complex&apos; SubClassOf &apos;part of&apos; some &apos;nucleus&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990512</classIRI>
<classLabel>Cry-Per complex</classLabel>
<deletedAxiom>&apos;Cry-Per complex&apos; SubClassOf &apos;nuclear transcriptional repressor complex&apos;</deletedAxiom>
<newAxiom>&apos;Cry-Per complex&apos; SubClassOf &apos;part of&apos; some &apos;nucleus&apos;</newAxiom>
<newAxiom>&apos;Cry-Per complex&apos; SubClassOf &apos;transcriptional repressor complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990590</classIRI>
<classLabel>ATF1-ATF4 transcription factor complex</classLabel>
<newAxiom>&apos;ATF1-ATF4 transcription factor complex&apos; SubClassOf &apos;part of&apos; some &apos;nucleus&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990589</classIRI>
<classLabel>ATF4-CREB1 transcription factor complex</classLabel>
<newAxiom>&apos;ATF4-CREB1 transcription factor complex&apos; SubClassOf &apos;part of&apos; some &apos;nucleus&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003695</classIRI>
<classLabel>random coil DNA binding</classLabel>
<deletedAxiom>&apos;random coil DNA binding&apos; SubClassOf &apos;DNA binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990608</classIRI>
<classLabel>mitotic spindle pole body localization to nuclear envelope</classLabel>
<deletedAxiom>&apos;mitotic spindle pole body localization to nuclear envelope&apos; SubClassOf &apos;spindle pole body localization to nuclear envelope&apos;</deletedAxiom>
<newAxiom>&apos;mitotic spindle pole body localization to nuclear envelope&apos; SubClassOf &apos;transports or maintains localization of&apos; some &apos;mitotic spindle pole body&apos;</newAxiom>
<newAxiom>&apos;mitotic spindle pole body localization to nuclear envelope&apos; SubClassOf &apos;spindle pole body localization&apos;</newAxiom>
<newAxiom>&apos;mitotic spindle pole body localization to nuclear envelope&apos; EquivalentTo &apos;localization&apos; and (&apos;transports or maintains localization of&apos; some &apos;mitotic spindle pole body&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_29859</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_29859 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990707</classIRI>
<classLabel>nuclear subtelomeric heterochromatin</classLabel>
<newAxiom>&apos;nuclear subtelomeric heterochromatin&apos; SubClassOf &apos;nuclear chromosome, telomeric region&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990711</classIRI>
<classLabel>Beta-catenin-ICAT complex</classLabel>
<deletedAxiom>&apos;Beta-catenin-ICAT complex&apos; SubClassOf &apos;nuclear transcriptional repressor complex&apos;</deletedAxiom>
<newAxiom>&apos;Beta-catenin-ICAT complex&apos; SubClassOf &apos;part of&apos; some &apos;nucleoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_477693</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_477693 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_54032</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_54032 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990944</classIRI>
<classLabel>maintenance of spindle pole body localization</classLabel>
<deletedAxiom>&apos;maintenance of spindle pole body localization&apos; SubClassOf &apos;part of&apos; some &apos;spindle pole body localization&apos;</deletedAxiom>
<deletedAxiom>&apos;maintenance of spindle pole body localization&apos; SubClassOf &apos;maintenance of organelle location&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_140409</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_140409 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_93810</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_93810 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_1198135</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_1198135 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902795</classIRI>
<classLabel>heterochromatin domain assembly</classLabel>
<deletedAxiom>&apos;heterochromatin domain assembly&apos; SubClassOf &apos;heterochromatin assembly&apos;</deletedAxiom>
<newAxiom>&apos;heterochromatin domain assembly&apos; SubClassOf &apos;heterochromatin organization&apos;</newAxiom>
<newAxiom>&apos;heterochromatin domain assembly&apos; SubClassOf &apos;chromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902794</classIRI>
<classLabel>heterochromatin island assembly</classLabel>
<deletedAxiom>&apos;heterochromatin island assembly&apos; SubClassOf &apos;heterochromatin assembly&apos;</deletedAxiom>
<newAxiom>&apos;heterochromatin island assembly&apos; SubClassOf &apos;chromatin assembly&apos;</newAxiom>
<newAxiom>&apos;heterochromatin island assembly&apos; SubClassOf &apos;heterochromatin organization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_654221</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_654221 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902801</classIRI>
<classLabel>regulation of heterochromatin island assembly</classLabel>
<deletedAxiom>&apos;regulation of heterochromatin island assembly&apos; SubClassOf &apos;regulation of heterochromatin assembly&apos;</deletedAxiom>
<newAxiom>&apos;regulation of heterochromatin island assembly&apos; SubClassOf &apos;regulation of chromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902802</classIRI>
<classLabel>regulation of heterochromatin domain assembly</classLabel>
<deletedAxiom>&apos;regulation of heterochromatin domain assembly&apos; SubClassOf &apos;regulation of heterochromatin assembly&apos;</deletedAxiom>
<newAxiom>&apos;regulation of heterochromatin domain assembly&apos; SubClassOf &apos;regulation of chromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_992401</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_992401 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150104</classIRI>
<classLabel>transport across blood-brain barrier</classLabel>
<deletedAxiom>&apos;transport across blood-brain barrier&apos; SubClassOf &apos;transport&apos;</deletedAxiom>
<deletedAxiom>&apos;transport across blood-brain barrier&apos; EquivalentTo &apos;transport&apos; and (&apos;results in transport across&apos; some &apos;blood brain barrier&apos;)</deletedAxiom>
<newAxiom>&apos;transport across blood-brain barrier&apos; EquivalentTo &apos;vascular transport&apos; and (&apos;results in transport across&apos; some &apos;blood brain barrier&apos;)</newAxiom>
<newAxiom>&apos;transport across blood-brain barrier&apos; SubClassOf &apos;vascular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_34425</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_34425 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140405</classIRI>
<classLabel>spindle pole body-led chromosome movement during mitotic interphase</classLabel>
<deletedAxiom>&apos;spindle pole body-led chromosome movement during mitotic interphase&apos; SubClassOf &apos;establishment of spindle pole body localization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017053</classIRI>
<classLabel>transcriptional repressor complex</classLabel>
<deletedAxiom>&apos;transcriptional repressor complex&apos; SubClassOf &apos;capable of part of&apos; some &apos;negative regulation of nucleic acid-templated transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;transcriptional repressor complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;capable of part of&apos; some &apos;negative regulation of nucleic acid-templated transcription&apos;)</deletedAxiom>
<deletedAxiom>&apos;transcriptional repressor complex&apos; SubClassOf &apos;protein-containing complex&apos;</deletedAxiom>
<newAxiom>&apos;transcriptional repressor complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;capable of&apos; some &apos;DNA-binding transcription repressor activity&apos;)</newAxiom>
<newAxiom>&apos;transcriptional repressor complex&apos; SubClassOf &apos;transcription factor complex&apos;</newAxiom>
<newAxiom>&apos;transcriptional repressor complex&apos; SubClassOf &apos;capable of&apos; some &apos;DNA-binding transcription repressor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_10633</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_10633 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_10634</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_10634 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_10624</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_10624 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_1445966</classIRI>
<classLabel>Gnetidae</classLabel>
<deletedAxiom>&apos;Gnetidae&apos; DisjointWith &apos;Coniferophyta&apos;</deletedAxiom>
<deletedAxiom>&apos;Gnetidae&apos; SubClassOf &apos;Acrogymnospermae&apos;</deletedAxiom>
<deletedAxiom>&apos;Gnetidae&apos; DisjointWith &apos;Gnetophyta&apos;</deletedAxiom>
<newAxiom>&apos;Gnetidae&apos; SubClassOf http://purl.obolibrary.org/obo/NCBITaxon_3372</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_10559</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_10559 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140312</classIRI>
<classLabel>cargo adaptor activity</classLabel>
<deletedAxiom>&apos;cargo adaptor activity&apos; SubClassOf &apos;molecular adaptor activity&apos;</deletedAxiom>
<newAxiom>&apos;cargo adaptor activity&apos; SubClassOf &apos;protein-macromolecule adaptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_9241</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_9241 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_44014</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_44014 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032452</classIRI>
<classLabel>histone demethylase activity</classLabel>
<deletedAxiom>&apos;histone demethylase activity&apos; SubClassOf &apos;demethylase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;histone demethylase activity&apos; SubClassOf &apos;catalytic activity, acting on a protein&apos;</deletedAxiom>
<newAxiom>&apos;histone demethylase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140457</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_10857</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_10857 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_184226</classIRI>
<deletedAxiom>http://purl.obolibrary.org/obo/NCBITaxon_184226 SubClassOf http://www.w3.org/2002/07/owl#Thing</deletedAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_3372</classIRI>
<classLabel>Gnetopsida</classLabel>
<newAxiom>'Gnetopsida' DisjointWith 'Gnetophyta'</newAxiom>
<newAxiom>'Gnetopsida' SubClassOf 'in taxon' some 'Gnetopsida'</newAxiom>
<newAxiom>'Gnetopsida' SubClassOf 'Acrogymnospermae'</newAxiom>
<newAxiom>'Coniferophyta' DisjointWith 'Gnetopsida'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/PATO_0001407</classIRI>
<classLabel>mononucleate</classLabel>
<newAxiom>'mononucleate' SubClassOf 'nucleated'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/PATO_0001408</classIRI>
<classLabel>ciliatedness</classLabel>
<newAxiom>'ciliatedness' SubClassOf 'cellular quality'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/PATO_0001405</classIRI>
<classLabel>anucleate</classLabel>
<newAxiom>'anucleate' SubClassOf 'nucleate quality'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/PATO_0001406</classIRI>
<classLabel>binucleate</classLabel>
<newAxiom>'binucleate' SubClassOf 'multinucleate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/PATO_0001404</classIRI>
<classLabel>nucleate quality</classLabel>
<newAxiom>'nucleate quality' SubClassOf 'cellular quality'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/PATO_0001396</classIRI>
<classLabel>cellular quality</classLabel>
<newAxiom>'cellular quality' SubClassOf 'physical object quality'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_1206795</classIRI>
<classLabel>Lophotrochozoa</classLabel>
<newAxiom>'Lophotrochozoa' SubClassOf 'Spiralia'</newAxiom>
<newAxiom>'Lophotrochozoa' SubClassOf 'in taxon' some 'Lophotrochozoa'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/PATO_0001908</classIRI>
<classLabel>multinucleate</classLabel>
<newAxiom>'multinucleate' SubClassOf 'nucleated'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/PATO_0002505</classIRI>
<classLabel>nucleated</classLabel>
<newAxiom>'nucleated' SubClassOf 'nucleate quality'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_2697495</classIRI>
<classLabel>Spiralia</classLabel>
<newAxiom>'Spiralia' SubClassOf 'in taxon' some 'Spiralia'</newAxiom>
<newAxiom>'Ecdysozoa' DisjointWith 'Spiralia'</newAxiom>
<newAxiom>'Spiralia' SubClassOf 'Protostomia'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_2611341</classIRI>
<classLabel>Metamonada</classLabel>
<newAxiom>'Metamonada' SubClassOf 'in taxon' some 'Metamonada'</newAxiom>
<newAxiom>'Metamonada' DisjointWith 'Discoba'</newAxiom>
<newAxiom>'Metamonada' SubClassOf 'Eukaryota'</newAxiom>
<newAxiom>'Metamonada' DisjointWith 'Amoebozoa'</newAxiom>
<newAxiom>'Metamonada' DisjointWith 'Viridiplantae'</newAxiom>
<newAxiom>'Metamonada' DisjointWith 'Sar'</newAxiom>
<newAxiom>'Metamonada' DisjointWith 'Opisthokonta'</newAxiom>
<newAxiom>'Metamonada' DisjointWith 'Glaucocystophyceae'</newAxiom>
<newAxiom>'Metamonada' DisjointWith 'Cryptophyceae'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_2611352</classIRI>
<classLabel>Discoba</classLabel>
<newAxiom>'Discoba' DisjointWith 'Opisthokonta'</newAxiom>
<newAxiom>'Metamonada' DisjointWith 'Discoba'</newAxiom>
<newAxiom>'Discoba' DisjointWith 'Glaucocystophyceae'</newAxiom>
<newAxiom>'Discoba' DisjointWith 'Sar'</newAxiom>
<newAxiom>'Discoba' SubClassOf 'in taxon' some 'Discoba'</newAxiom>
<newAxiom>'Discoba' SubClassOf 'Eukaryota'</newAxiom>
<newAxiom>'Discoba' DisjointWith 'Amoebozoa'</newAxiom>
<newAxiom>'Discoba' DisjointWith 'Viridiplantae'</newAxiom>
<newAxiom>'Discoba' DisjointWith 'Cryptophyceae'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_2698737</classIRI>
<classLabel>Sar</classLabel>
<newAxiom>'Discoba' DisjointWith 'Sar'</newAxiom>
<newAxiom>'Sar' DisjointWith 'Cryptophyceae'</newAxiom>
<newAxiom>'Sar' DisjointWith 'Glaucocystophyceae'</newAxiom>
<newAxiom>'Sar' DisjointWith 'Viridiplantae'</newAxiom>
<newAxiom>'Sar' DisjointWith 'Amoebozoa'</newAxiom>
<newAxiom>'Metamonada' DisjointWith 'Sar'</newAxiom>
<newAxiom>'Sar' SubClassOf 'Eukaryota'</newAxiom>
<newAxiom>'Sar' SubClassOf 'in taxon' some 'Sar'</newAxiom>
<newAxiom>'Sar' DisjointWith 'Opisthokonta'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106257</classIRI>
<classLabel>glycerol-3-phosphate dehydrogenase [NADP+] activity</classLabel>
<newAxiom>'glycerol-3-phosphate dehydrogenase [NADP+] activity' SubClassOf 'glycerol-3-phosphate dehydrogenase [NAD(P)+] activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106258</classIRI>
<classLabel>L-serine-phosphatidylcholine phosphatidyltransferase activity</classLabel>
<newAxiom>'L-serine-phosphatidylcholine phosphatidyltransferase activity' SubClassOf 'phosphotransferase activity, for other substituted phosphate groups'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062245</classIRI>
<classLabel>double membrane vesicle viral factory inner membrane</classLabel>
<newAxiom>'double membrane vesicle viral factory inner membrane' SubClassOf 'double membrane vesicle viral factory membrane'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062244</classIRI>
<classLabel>double membrane vesicle viral factory lumen</classLabel>
<newAxiom>'double membrane vesicle viral factory lumen' SubClassOf 'host cell cytoplasm part'</newAxiom>
<newAxiom>'double membrane vesicle viral factory lumen' SubClassOf 'part of' some 'double membrane vesicle viral factory'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062243</classIRI>
<classLabel>double membrane vesicle viral factory outer membrane</classLabel>
<newAxiom>'double membrane vesicle viral factory outer membrane' SubClassOf 'double membrane vesicle viral factory membrane'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062242</classIRI>
<classLabel>double membrane vesicle viral factory membrane</classLabel>
<newAxiom>'double membrane vesicle viral factory membrane' EquivalentTo 'host cell cytoplasmic vesicle membrane' and ('part of' some 'double membrane vesicle viral factory')</newAxiom>
<newAxiom>'double membrane vesicle viral factory membrane' SubClassOf 'part of' some 'double membrane vesicle viral factory'</newAxiom>
<newAxiom>'double membrane vesicle viral factory membrane' SubClassOf 'host cell cytoplasmic vesicle membrane'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062241</classIRI>
<classLabel>double strand break-nuclear membrane anchor activity</classLabel>
<newAxiom>'double strand break-nuclear membrane anchor activity' SubClassOf 'protein-membrane adaptor activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062240</classIRI>
<classLabel>euchromatin-nuclear membrane anchor activity</classLabel>
<newAxiom>'euchromatin-nuclear membrane anchor activity' SubClassOf 'protein-membrane adaptor activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062236</classIRI>
<classLabel>ionocyte differentiation</classLabel>
<newAxiom>'ionocyte differentiation' SubClassOf 'epithelial cell differentiation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062235</classIRI>
<classLabel>axonemal basal plate assembly</classLabel>
<newAxiom>'axonemal basal plate assembly' SubClassOf 'results in assembly of' some 'axonemal basal plate'</newAxiom>
<newAxiom>'axonemal basal plate assembly' EquivalentTo 'cellular process' and ('results in assembly of' some 'axonemal basal plate')</newAxiom>
<newAxiom>'axonemal basal plate assembly' SubClassOf 'cellular component assembly'</newAxiom>
<newAxiom>'axonemal basal plate assembly' SubClassOf 'part of' some 'axoneme assembly'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062239</classIRI>
<classLabel>heterochromatin-nuclear membrane anchor activity</classLabel>
<newAxiom>'heterochromatin-nuclear membrane anchor activity' SubClassOf 'protein-membrane adaptor activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062238</classIRI>
<classLabel>Smp focus</classLabel>
<newAxiom>'Smp focus' SubClassOf 'ribonucleoprotein complex'</newAxiom>
<newAxiom>'Smp focus' SubClassOf 'part of' some 'nuclear chromosome'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062237</classIRI>
<classLabel>protein localization to postsynapse</classLabel>
<newAxiom>'protein localization to postsynapse' EquivalentTo 'protein localization' and ('has target end location' some 'postsynapse')</newAxiom>
<newAxiom>'protein localization to postsynapse' SubClassOf 'protein localization to synapse'</newAxiom>
<newAxiom>'protein localization to postsynapse' SubClassOf 'has target end location' some 'postsynapse'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_2704949</classIRI>
<classLabel>Trypanosomatida</classLabel>
<newAxiom>'Trypanosomatida' SubClassOf 'in taxon' some 'Trypanosomatida'</newAxiom>
<newAxiom>'Trypanosomatida' SubClassOf 'Metakinetoplastina'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150201</classIRI>
<classLabel>positive regulation of transport across blood-brain barrier</classLabel>
<newAxiom>'positive regulation of transport across blood-brain barrier' SubClassOf 'positive regulation of transport'</newAxiom>
<newAxiom>'positive regulation of transport across blood-brain barrier' EquivalentTo 'biological regulation' and ('positively regulates' some 'transport across blood-brain barrier')</newAxiom>
<newAxiom>'positive regulation of transport across blood-brain barrier' SubClassOf 'regulation of transport across blood-brain barrier'</newAxiom>
<newAxiom>'positive regulation of transport across blood-brain barrier' SubClassOf 'positively regulates' some 'transport across blood-brain barrier'</newAxiom>
<newAxiom>'positive regulation of transport across blood-brain barrier' SubClassOf 'part of' some 'positive regulation of vascular permeability'</newAxiom>
<newAxiom>'positive regulation of transport across blood-brain barrier' SubClassOf 'positive regulation of multicellular organismal process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150200</classIRI>
<classLabel>regulation of transport across blood-brain barrier</classLabel>
<newAxiom>'regulation of transport across blood-brain barrier' SubClassOf 'part of' some 'regulation of vascular permeability'</newAxiom>
<newAxiom>'regulation of transport across blood-brain barrier' SubClassOf 'regulation of system process'</newAxiom>
<newAxiom>'regulation of transport across blood-brain barrier' SubClassOf 'regulates' some 'transport across blood-brain barrier'</newAxiom>
<newAxiom>'regulation of transport across blood-brain barrier' EquivalentTo 'biological regulation' and ('regulates' some 'transport across blood-brain barrier')</newAxiom>
<newAxiom>'regulation of transport across blood-brain barrier' SubClassOf 'regulation of transport'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150202</classIRI>
<classLabel>negative regulation of transport across blood-brain barrier</classLabel>
<newAxiom>'negative regulation of transport across blood-brain barrier' EquivalentTo 'biological regulation' and ('negatively regulates' some 'transport across blood-brain barrier')</newAxiom>
<newAxiom>'negative regulation of transport across blood-brain barrier' SubClassOf 'negative regulation of transport'</newAxiom>
<newAxiom>'negative regulation of transport across blood-brain barrier' SubClassOf 'part of' some 'negative regulation of vascular permeability'</newAxiom>
<newAxiom>'negative regulation of transport across blood-brain barrier' SubClassOf 'regulation of transport across blood-brain barrier'</newAxiom>
<newAxiom>'negative regulation of transport across blood-brain barrier' SubClassOf 'negative regulation of multicellular organismal process'</newAxiom>
<newAxiom>'negative regulation of transport across blood-brain barrier' SubClassOf 'negatively regulates' some 'transport across blood-brain barrier'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_2704647</classIRI>
<classLabel>Metakinetoplastina</classLabel>
<newAxiom>'Metakinetoplastina' SubClassOf 'Kinetoplastea'</newAxiom>
<newAxiom>'Metakinetoplastina' SubClassOf 'in taxon' some 'Metakinetoplastina'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150195</classIRI>
<classLabel>transport across blood-cerebrospinal fluid barrier</classLabel>
<newAxiom>'transport across blood-cerebrospinal fluid barrier' SubClassOf 'results in transport across' some 'blood-cerebrospinal fluid barrier'</newAxiom>
<newAxiom>'transport across blood-cerebrospinal fluid barrier' SubClassOf 'vascular transport'</newAxiom>
<newAxiom>'transport across blood-cerebrospinal fluid barrier' EquivalentTo 'transport' and ('results in transport across' some 'blood-cerebrospinal fluid barrier')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_2684882</classIRI>
<classLabel>Zygnematophycidae</classLabel>
<newAxiom>'Zygnematophycidae' SubClassOf 'in taxon' some 'Zygnematophycidae'</newAxiom>
<newAxiom>'Zygnematophycidae' SubClassOf 'Zygnemophyceae'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140457</classIRI>
<classLabel>protein demethylase activity</classLabel>
<newAxiom>'protein demethylase activity' SubClassOf 'catalytic activity, acting on a protein'</newAxiom>
<newAxiom>'protein demethylase activity' SubClassOf 'demethylase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140456</classIRI>
<classLabel>meiotic spindle pole body duplication</classLabel>
<newAxiom>'meiotic spindle pole body duplication' SubClassOf 'initial mitotic spindle pole body separation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140455</classIRI>
<classLabel>cytoplasm protein quality control</classLabel>
<newAxiom>'cytoplasm protein quality control' SubClassOf 'protein quality control for misfolded or incompletely synthesized proteins'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140454</classIRI>
<classLabel>protein aggregate center assembly</classLabel>
<newAxiom>'protein aggregate center assembly' SubClassOf 'cellular component assembly'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140446</classIRI>
<classLabel>fumigermin biosynthetic process</classLabel>
<newAxiom>'fumigermin biosynthetic process' SubClassOf 'only_in_taxon' some 'Fungi'</newAxiom>
<newAxiom>'fumigermin biosynthetic process' SubClassOf 'secondary metabolite biosynthetic process'</newAxiom>
<newAxiom>'fumigermin biosynthetic process' SubClassOf 'in taxon' only 'Fungi'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140445</classIRI>
<classLabel>chromosome, telomeric repeat region</classLabel>
<newAxiom>'chromosome, telomeric repeat region' SubClassOf 'chromosome, telomeric region'</newAxiom>
</newClass>
<newClass>
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