<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
65
</numberChangedClasses>
<numberNewClasses>
7
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044212</classIRI>
<classLabel>transcription regulatory region DNA binding</classLabel>
<deletedAxiom>&apos;transcription regulatory region DNA binding&apos; SubClassOf &apos;regulatory region nucleic acid binding&apos;</deletedAxiom>
<deletedAxiom>&apos;transcription regulatory region DNA binding&apos; SubClassOf &apos;DNA binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044213</classIRI>
<classLabel>intronic transcription regulatory region DNA binding</classLabel>
<deletedAxiom>&apos;intronic transcription regulatory region DNA binding&apos; SubClassOf &apos;transcription regulatory region DNA binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000987</classIRI>
<classLabel>cis-regulatory region sequence-specific DNA binding</classLabel>
<deletedAxiom>&apos;cis-regulatory region sequence-specific DNA binding&apos; SubClassOf &apos;cis-regulatory region binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000984</classIRI>
<classLabel>bacterial-type RNA polymerase regulatory region sequence-specific DNA binding</classLabel>
<deletedAxiom>&apos;bacterial-type RNA polymerase regulatory region sequence-specific DNA binding&apos; SubClassOf &apos;bacterial-type RNA polymerase regulatory region DNA binding&apos;</deletedAxiom>
<newAxiom>&apos;bacterial-type RNA polymerase regulatory region sequence-specific DNA binding&apos; SubClassOf &apos;in taxon&apos; only &apos;Bacteria&apos;</newAxiom>
<newAxiom>&apos;bacterial-type RNA polymerase regulatory region sequence-specific DNA binding&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Bacteria&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000976</classIRI>
<classLabel>transcription regulatory region sequence-specific DNA binding</classLabel>
<deletedAxiom>&apos;transcription regulatory region sequence-specific DNA binding&apos; SubClassOf &apos;transcription regulatory region DNA binding&apos;</deletedAxiom>
<newAxiom>&apos;transcription regulatory region sequence-specific DNA binding&apos; SubClassOf &apos;regulatory region nucleic acid binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000977</classIRI>
<classLabel>RNA polymerase II regulatory region sequence-specific DNA binding</classLabel>
<deletedAxiom>&apos;RNA polymerase II regulatory region sequence-specific DNA binding&apos; SubClassOf &apos;RNA polymerase II regulatory region DNA binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000677</classIRI>
<classLabel>regulation of transcription regulatory region DNA binding</classLabel>
<deletedAxiom>&apos;regulation of transcription regulatory region DNA binding&apos; SubClassOf &apos;regulates&apos; some &apos;transcription regulatory region DNA binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription regulatory region DNA binding&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;transcription regulatory region DNA binding&apos;)</deletedAxiom>
<newAxiom>&apos;regulation of transcription regulatory region DNA binding&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;transcription regulatory region sequence-specific DNA binding&apos;)</newAxiom>
<newAxiom>&apos;regulation of transcription regulatory region DNA binding&apos; SubClassOf &apos;regulates&apos; some &apos;transcription regulatory region sequence-specific DNA binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000678</classIRI>
<classLabel>negative regulation of transcription regulatory region DNA binding</classLabel>
<deletedAxiom>&apos;negative regulation of transcription regulatory region DNA binding&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;transcription regulatory region DNA binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription regulatory region DNA binding&apos; SubClassOf &apos;negatively regulates&apos; some &apos;transcription regulatory region DNA binding&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of transcription regulatory region DNA binding&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;transcription regulatory region sequence-specific DNA binding&apos;)</newAxiom>
<newAxiom>&apos;negative regulation of transcription regulatory region DNA binding&apos; SubClassOf &apos;negatively regulates&apos; some &apos;transcription regulatory region sequence-specific DNA binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000679</classIRI>
<classLabel>positive regulation of transcription regulatory region DNA binding</classLabel>
<deletedAxiom>&apos;positive regulation of transcription regulatory region DNA binding&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;transcription regulatory region DNA binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription regulatory region DNA binding&apos; SubClassOf &apos;positively regulates&apos; some &apos;transcription regulatory region DNA binding&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of transcription regulatory region DNA binding&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;transcription regulatory region sequence-specific DNA binding&apos;)</newAxiom>
<newAxiom>&apos;positive regulation of transcription regulatory region DNA binding&apos; SubClassOf &apos;positively regulates&apos; some &apos;transcription regulatory region sequence-specific DNA binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060803</classIRI>
<classLabel>BMP signaling pathway involved in mesodermal cell fate specification</classLabel>
<deletedAxiom>&apos;BMP signaling pathway involved in mesodermal cell fate specification&apos; SubClassOf &apos;regulation of transcription involved in primary germ layer cell fate commitment&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035326</classIRI>
<classLabel>cis-regulatory region binding</classLabel>
<deletedAxiom>&apos;cis-regulatory region binding&apos; SubClassOf &apos;transcription regulatory region DNA binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035391</classIRI>
<classLabel>maintenance of chromatin silencing at silent mating-type cassette</classLabel>
<deletedAxiom>&apos;maintenance of chromatin silencing at silent mating-type cassette&apos; SubClassOf &apos;heterochromatin maintenance&apos;</deletedAxiom>
<deletedAxiom>&apos;maintenance of chromatin silencing at silent mating-type cassette&apos; SubClassOf &apos;part of&apos; some &apos;silent mating-type cassette heterochromatin assembly&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035392</classIRI>
<classLabel>maintenance of chromatin silencing at telomere</classLabel>
<deletedAxiom>&apos;maintenance of chromatin silencing at telomere&apos; SubClassOf &apos;heterochromatin maintenance&apos;</deletedAxiom>
<deletedAxiom>&apos;maintenance of chromatin silencing at telomere&apos; SubClassOf &apos;part of&apos; some &apos;chromatin silencing at telomere&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035012</classIRI>
<classLabel>polytene chromosome, telomeric region</classLabel>
<deletedAxiom>&apos;polytene chromosome, telomeric region&apos; EquivalentTo &apos;chromosome, telomeric region&apos; and (&apos;part of&apos; some &apos;polytene chromosome&apos;)</deletedAxiom>
<deletedAxiom>&apos;polytene chromosome, telomeric region&apos; SubClassOf &apos;chromosome, telomeric region&apos;</deletedAxiom>
<deletedAxiom>&apos;polytene chromosome, telomeric region&apos; SubClassOf &apos;part of&apos; some &apos;polytene chromosome&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905548</classIRI>
<classLabel>negative regulation of subtelomeric heterochromatin assembly</classLabel>
<deletedAxiom>&apos;negative regulation of subtelomeric heterochromatin assembly&apos; SubClassOf &apos;negative regulation of chromatin assembly or disassembly&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of subtelomeric heterochromatin assembly&apos; SubClassOf &apos;negative regulation of heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905549</classIRI>
<classLabel>positive regulation of subtelomeric heterochromatin assembly</classLabel>
<deletedAxiom>&apos;positive regulation of subtelomeric heterochromatin assembly&apos; SubClassOf &apos;positive regulation of cellular component biogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of subtelomeric heterochromatin assembly&apos; SubClassOf &apos;positive regulation of chromatin assembly or disassembly&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of subtelomeric heterochromatin assembly&apos; SubClassOf &apos;positive regulation of heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905547</classIRI>
<classLabel>regulation of subtelomeric heterochromatin assembly</classLabel>
<deletedAxiom>&apos;regulation of subtelomeric heterochromatin assembly&apos; SubClassOf &apos;regulation of chromatin assembly&apos;</deletedAxiom>
<newAxiom>&apos;regulation of subtelomeric heterochromatin assembly&apos; SubClassOf &apos;regulation of heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001163</classIRI>
<classLabel>RNA polymerase I regulatory region sequence-specific DNA binding</classLabel>
<deletedAxiom>&apos;RNA polymerase I regulatory region sequence-specific DNA binding&apos; SubClassOf &apos;RNA polymerase I regulatory region DNA binding&apos;</deletedAxiom>
<newAxiom>&apos;RNA polymerase I regulatory region sequence-specific DNA binding&apos; SubClassOf &apos;transcription regulatory region sequence-specific DNA binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001160</classIRI>
<classLabel>transcription termination site DNA binding</classLabel>
<deletedAxiom>&apos;transcription termination site DNA binding&apos; SubClassOf &apos;transcription regulatory region DNA binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001161</classIRI>
<classLabel>intronic transcription regulatory region sequence-specific DNA binding</classLabel>
<deletedAxiom>&apos;intronic transcription regulatory region sequence-specific DNA binding&apos; SubClassOf &apos;intronic transcription regulatory region DNA binding&apos;</deletedAxiom>
<newAxiom>&apos;intronic transcription regulatory region sequence-specific DNA binding&apos; SubClassOf &apos;transcription regulatory region sequence-specific DNA binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001147</classIRI>
<classLabel>transcription termination site sequence-specific DNA binding</classLabel>
<deletedAxiom>&apos;transcription termination site sequence-specific DNA binding&apos; SubClassOf &apos;transcription termination site DNA binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001047</classIRI>
<classLabel>core promoter binding</classLabel>
<deletedAxiom>&apos;core promoter binding&apos; SubClassOf &apos;transcription regulatory region DNA binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001046</classIRI>
<classLabel>core promoter sequence-specific DNA binding</classLabel>
<deletedAxiom>&apos;core promoter sequence-specific DNA binding&apos; SubClassOf &apos;core promoter binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001039</classIRI>
<classLabel>RNA polymerase III hybrid type promoter sequence-specific DNA binding</classLabel>
<deletedAxiom>&apos;RNA polymerase III hybrid type promoter sequence-specific DNA binding&apos; SubClassOf &apos;RNA polymerase III hybrid type promoter DNA binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001037</classIRI>
<classLabel>RNA polymerase III hybrid type promoter DNA binding</classLabel>
<deletedAxiom>&apos;RNA polymerase III hybrid type promoter DNA binding&apos; SubClassOf &apos;RNA polymerase III regulatory region DNA binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001032</classIRI>
<classLabel>RNA polymerase III type 3 promoter DNA binding</classLabel>
<deletedAxiom>&apos;RNA polymerase III type 3 promoter DNA binding&apos; SubClassOf &apos;RNA polymerase III regulatory region DNA binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001030</classIRI>
<classLabel>RNA polymerase III type 1 promoter DNA binding</classLabel>
<deletedAxiom>&apos;RNA polymerase III type 1 promoter DNA binding&apos; SubClassOf &apos;RNA polymerase III regulatory region DNA binding&apos;</deletedAxiom>
<deletedAxiom>&apos;RNA polymerase III type 1 promoter DNA binding&apos; SubClassOf &apos;5S rDNA binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001031</classIRI>
<classLabel>RNA polymerase III type 2 promoter DNA binding</classLabel>
<deletedAxiom>&apos;RNA polymerase III type 2 promoter DNA binding&apos; SubClassOf &apos;RNA polymerase III regulatory region DNA binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001018</classIRI>
<classLabel>mitochondrial promoter sequence-specific DNA binding</classLabel>
<deletedAxiom>&apos;mitochondrial promoter sequence-specific DNA binding&apos; SubClassOf &apos;transcription regulatory region DNA binding&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial promoter sequence-specific DNA binding&apos; SubClassOf &apos;transcription regulatory region sequence-specific DNA binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001019</classIRI>
<classLabel>plastid RNA polymerase regulatory region DNA binding</classLabel>
<deletedAxiom>&apos;plastid RNA polymerase regulatory region DNA binding&apos; SubClassOf &apos;transcription regulatory region DNA binding&apos;</deletedAxiom>
<newAxiom>&apos;plastid RNA polymerase regulatory region DNA binding&apos; SubClassOf &apos;transcription regulatory region sequence-specific DNA binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001016</classIRI>
<classLabel>RNA polymerase III regulatory region DNA binding</classLabel>
<deletedAxiom>&apos;RNA polymerase III regulatory region DNA binding&apos; SubClassOf &apos;transcription regulatory region DNA binding&apos;</deletedAxiom>
<newAxiom>&apos;RNA polymerase III regulatory region DNA binding&apos; SubClassOf &apos;transcription regulatory region sequence-specific DNA binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001017</classIRI>
<classLabel>bacterial-type RNA polymerase regulatory region DNA binding</classLabel>
<deletedAxiom>&apos;bacterial-type RNA polymerase regulatory region DNA binding&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Bacteria&apos;</deletedAxiom>
<deletedAxiom>&apos;bacterial-type RNA polymerase regulatory region DNA binding&apos; SubClassOf &apos;in taxon&apos; only &apos;Bacteria&apos;</deletedAxiom>
<deletedAxiom>&apos;bacterial-type RNA polymerase regulatory region DNA binding&apos; SubClassOf &apos;transcription regulatory region DNA binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001012</classIRI>
<classLabel>RNA polymerase II regulatory region DNA binding</classLabel>
<deletedAxiom>&apos;RNA polymerase II regulatory region DNA binding&apos; SubClassOf &apos;transcription regulatory region DNA binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001013</classIRI>
<classLabel>RNA polymerase I regulatory region DNA binding</classLabel>
<deletedAxiom>&apos;RNA polymerase I regulatory region DNA binding&apos; SubClassOf &apos;transcription regulatory region DNA binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001006</classIRI>
<classLabel>RNA polymerase III type 3 promoter sequence-specific DNA binding</classLabel>
<deletedAxiom>&apos;RNA polymerase III type 3 promoter sequence-specific DNA binding&apos; SubClassOf &apos;RNA polymerase III type 3 promoter DNA binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001003</classIRI>
<classLabel>RNA polymerase III type 2 promoter sequence-specific DNA binding</classLabel>
<deletedAxiom>&apos;RNA polymerase III type 2 promoter sequence-specific DNA binding&apos; SubClassOf &apos;RNA polymerase III type 2 promoter DNA binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001002</classIRI>
<classLabel>RNA polymerase III type 1 promoter sequence-specific DNA binding</classLabel>
<deletedAxiom>&apos;RNA polymerase III type 1 promoter sequence-specific DNA binding&apos; SubClassOf &apos;RNA polymerase III type 1 promoter DNA binding&apos;</deletedAxiom>
<newAxiom>&apos;RNA polymerase III type 1 promoter sequence-specific DNA binding&apos; SubClassOf &apos;5S rDNA binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904796</classIRI>
<classLabel>regulation of core promoter binding</classLabel>
<deletedAxiom>&apos;regulation of core promoter binding&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;core promoter binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of core promoter binding&apos; SubClassOf &apos;regulates&apos; some &apos;core promoter binding&apos;</deletedAxiom>
<newAxiom>&apos;regulation of core promoter binding&apos; SubClassOf &apos;regulates&apos; some &apos;core promoter sequence-specific DNA binding&apos;</newAxiom>
<newAxiom>&apos;regulation of core promoter binding&apos; EquivalentTo &apos;biological_process&apos; and (&apos;regulates&apos; some &apos;core promoter sequence-specific DNA binding&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904797</classIRI>
<classLabel>negative regulation of core promoter binding</classLabel>
<deletedAxiom>&apos;negative regulation of core promoter binding&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;core promoter binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of core promoter binding&apos; SubClassOf &apos;negatively regulates&apos; some &apos;core promoter binding&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of core promoter binding&apos; SubClassOf &apos;negatively regulates&apos; some &apos;core promoter sequence-specific DNA binding&apos;</newAxiom>
<newAxiom>&apos;negative regulation of core promoter binding&apos; EquivalentTo &apos;biological_process&apos; and (&apos;negatively regulates&apos; some &apos;core promoter sequence-specific DNA binding&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904798</classIRI>
<classLabel>positive regulation of core promoter binding</classLabel>
<deletedAxiom>&apos;positive regulation of core promoter binding&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;core promoter binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of core promoter binding&apos; SubClassOf &apos;positively regulates&apos; some &apos;core promoter binding&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of core promoter binding&apos; SubClassOf &apos;positively regulates&apos; some &apos;core promoter sequence-specific DNA binding&apos;</newAxiom>
<newAxiom>&apos;positive regulation of core promoter binding&apos; EquivalentTo &apos;biological_process&apos; and (&apos;positively regulates&apos; some &apos;core promoter sequence-specific DNA binding&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030510</classIRI>
<classLabel>regulation of BMP signaling pathway</classLabel>
<deletedAxiom>&apos;regulation of BMP signaling pathway&apos; SubClassOf &apos;regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030509</classIRI>
<classLabel>BMP signaling pathway</classLabel>
<deletedAxiom>&apos;BMP signaling pathway&apos; SubClassOf &apos;regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044409</classIRI>
<classLabel>entry into host</classLabel>
<deletedAxiom>&apos;entry into host&apos; SubClassOf &apos;interaction with host&apos;</deletedAxiom>
<newAxiom>&apos;entry into host&apos; SubClassOf &apos;movement in host environment&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071893</classIRI>
<classLabel>BMP signaling pathway involved in nephric duct formation</classLabel>
<deletedAxiom>&apos;BMP signaling pathway involved in nephric duct formation&apos; SubClassOf &apos;regulation of transcription from RNA polymerase II promoter involved in kidney development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061793</classIRI>
<classLabel>chromatin lock complex</classLabel>
<deletedAxiom>&apos;chromatin lock complex&apos; SubClassOf &apos;capable of&apos; some &apos;transcription regulatory region DNA binding&apos;</deletedAxiom>
<newAxiom>&apos;chromatin lock complex&apos; SubClassOf &apos;capable of&apos; some &apos;transcription regulatory region sequence-specific DNA binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022024</classIRI>
<classLabel>BMP signaling pathway involved in forebrain neuron fate commitment</classLabel>
<deletedAxiom>&apos;BMP signaling pathway involved in forebrain neuron fate commitment&apos; SubClassOf &apos;regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment&apos;</deletedAxiom>
<newAxiom>&apos;BMP signaling pathway involved in forebrain neuron fate commitment&apos; SubClassOf &apos;part of&apos; some &apos;commitment of multipotent stem cells to neuronal lineage in forebrain&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061312</classIRI>
<classLabel>BMP signaling pathway involved in heart development</classLabel>
<deletedAxiom>&apos;BMP signaling pathway involved in heart development&apos; SubClassOf &apos;regulation of transcription from RNA polymerase II promoter involved in heart development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110016</classIRI>
<classLabel>B-WICH complex</classLabel>
<deletedAxiom>&apos;B-WICH complex&apos; SubClassOf &apos;capable of&apos; some &apos;RNA polymerase I regulatory region DNA binding&apos;</deletedAxiom>
<newAxiom>&apos;B-WICH complex&apos; SubClassOf &apos;capable of&apos; some &apos;RNA polymerase I regulatory region sequence-specific DNA binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099114</classIRI>
<classLabel>chromatin silencing at subtelomere</classLabel>
<deletedAxiom>&apos;chromatin silencing at subtelomere&apos; EquivalentTo &apos;chromatin silencing&apos; and (&apos;occurs in&apos; some &apos;chromosome, subtelomeric region&apos;)</deletedAxiom>
<deletedAxiom>&apos;chromatin silencing at subtelomere&apos; SubClassOf &apos;occurs in&apos; some &apos;chromosome, subtelomeric region&apos;</deletedAxiom>
<deletedAxiom>&apos;chromatin silencing at subtelomere&apos; SubClassOf &apos;chromatin silencing at telomere&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031507</classIRI>
<classLabel>heterochromatin assembly</classLabel>
<deletedAxiom>&apos;heterochromatin assembly&apos; SubClassOf &apos;heterochromatin organization involved in chromatin silencing&apos;</deletedAxiom>
<newAxiom>&apos;heterochromatin assembly&apos; SubClassOf &apos;heterochromatin organization&apos;</newAxiom>
<newAxiom>&apos;heterochromatin assembly&apos; SubClassOf &apos;part of&apos; some &apos;chromatin organization involved in negative regulation of transcription&apos;</newAxiom>
<newAxiom>&apos;heterochromatin assembly&apos; SubClassOf &apos;chromatin organization involved in negative regulation of transcription&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031509</classIRI>
<classLabel>subtelomeric heterochromatin assembly</classLabel>
<deletedAxiom>&apos;subtelomeric heterochromatin assembly&apos; SubClassOf &apos;results in assembly of&apos; some &apos;nuclear subtelomeric heterochromatin&apos;</deletedAxiom>
<deletedAxiom>&apos;subtelomeric heterochromatin assembly&apos; EquivalentTo &apos;cellular component assembly&apos; and (&apos;results in assembly of&apos; some &apos;nuclear subtelomeric heterochromatin&apos;)</deletedAxiom>
<deletedAxiom>&apos;subtelomeric heterochromatin assembly&apos; SubClassOf &apos;heterochromatin organization&apos;</deletedAxiom>
<deletedAxiom>&apos;subtelomeric heterochromatin assembly&apos; SubClassOf &apos;telomere assembly&apos;</deletedAxiom>
<deletedAxiom>&apos;subtelomeric heterochromatin assembly&apos; SubClassOf &apos;chromatin assembly&apos;</deletedAxiom>
<newAxiom>&apos;subtelomeric heterochromatin assembly&apos; SubClassOf &apos;heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031445</classIRI>
<classLabel>regulation of heterochromatin assembly</classLabel>
<deletedAxiom>&apos;regulation of heterochromatin assembly&apos; SubClassOf &apos;regulation of chromatin silencing&apos;</deletedAxiom>
<newAxiom>&apos;regulation of heterochromatin assembly&apos; SubClassOf &apos;regulation of transcription, DNA-templated&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031452</classIRI>
<classLabel>negative regulation of heterochromatin assembly</classLabel>
<deletedAxiom>&apos;negative regulation of heterochromatin assembly&apos; SubClassOf &apos;negative regulation of chromatin silencing&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of heterochromatin assembly&apos; SubClassOf &apos;positive regulation of transcription, DNA-templated&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031453</classIRI>
<classLabel>positive regulation of heterochromatin assembly</classLabel>
<deletedAxiom>&apos;positive regulation of heterochromatin assembly&apos; SubClassOf &apos;positive regulation of chromatin silencing&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0080188</classIRI>
<classLabel>RNA-directed DNA methylation</classLabel>
<deletedAxiom>&apos;RNA-directed DNA methylation&apos; SubClassOf &apos;DNA methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;RNA-directed DNA methylation&apos; SubClassOf &apos;gene silencing by RNA&apos;</deletedAxiom>
<newAxiom>&apos;RNA-directed DNA methylation&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140458</newAxiom>
<newAxiom>&apos;RNA-directed DNA methylation&apos; SubClassOf &apos;has_part&apos; some &apos;DNA methylation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072101</classIRI>
<classLabel>specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway</classLabel>
<deletedAxiom>&apos;specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway&apos; SubClassOf &apos;regulation of transcription from RNA polymerase II promoter involved in mesonephros development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062236</classIRI>
<classLabel>ionocyte differentiation</classLabel>
<newAxiom>&apos;ionocyte differentiation&apos; SubClassOf &apos;results in acquisition of features of&apos; some http://purl.obolibrary.org/obo/CL_0005006</newAxiom>
<newAxiom>&apos;ionocyte differentiation&apos; EquivalentTo &apos;cell differentiation&apos; and (&apos;results in acquisition of features of&apos; some http://purl.obolibrary.org/obo/CL_0005006)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003154</classIRI>
<classLabel>BMP signaling pathway involved in determination of left/right symmetry</classLabel>
<deletedAxiom>&apos;BMP signaling pathway involved in determination of left/right symmetry&apos; SubClassOf &apos;regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry&apos;</deletedAxiom>
<newAxiom>&apos;BMP signaling pathway involved in determination of left/right symmetry&apos; SubClassOf &apos;part of&apos; some &apos;determination of left/right symmetry&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902795</classIRI>
<classLabel>heterochromatin domain assembly</classLabel>
<deletedAxiom>&apos;heterochromatin domain assembly&apos; SubClassOf &apos;heterochromatin organization&apos;</deletedAxiom>
<deletedAxiom>&apos;heterochromatin domain assembly&apos; SubClassOf &apos;chromatin assembly&apos;</deletedAxiom>
<newAxiom>&apos;heterochromatin domain assembly&apos; SubClassOf &apos;heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902794</classIRI>
<classLabel>heterochromatin island assembly</classLabel>
<deletedAxiom>&apos;heterochromatin island assembly&apos; SubClassOf &apos;chromatin assembly&apos;</deletedAxiom>
<deletedAxiom>&apos;heterochromatin island assembly&apos; SubClassOf &apos;heterochromatin organization&apos;</deletedAxiom>
<newAxiom>&apos;heterochromatin island assembly&apos; SubClassOf &apos;heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902801</classIRI>
<classLabel>regulation of heterochromatin island assembly</classLabel>
<deletedAxiom>&apos;regulation of heterochromatin island assembly&apos; SubClassOf &apos;regulation of chromatin assembly&apos;</deletedAxiom>
<newAxiom>&apos;regulation of heterochromatin island assembly&apos; SubClassOf &apos;regulation of heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902802</classIRI>
<classLabel>regulation of heterochromatin domain assembly</classLabel>
<deletedAxiom>&apos;regulation of heterochromatin domain assembly&apos; SubClassOf &apos;regulation of chromatin assembly&apos;</deletedAxiom>
<newAxiom>&apos;regulation of heterochromatin domain assembly&apos; SubClassOf &apos;regulation of heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140276</classIRI>
<classLabel>pericentric heterochromatin maintenance</classLabel>
<deletedAxiom>&apos;pericentric heterochromatin maintenance&apos; SubClassOf &apos;part of&apos; some &apos;pericentric heterochromatin assembly&apos;</deletedAxiom>
<deletedAxiom>&apos;pericentric heterochromatin maintenance&apos; SubClassOf &apos;heterochromatin maintenance&apos;</deletedAxiom>
<deletedAxiom>&apos;pericentric heterochromatin maintenance&apos; EquivalentTo &apos;heterochromatin maintenance&apos; and (&apos;part of&apos; some &apos;pericentric heterochromatin assembly&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032422</classIRI>
<classLabel>purine-rich negative regulatory element binding</classLabel>
<deletedAxiom>&apos;purine-rich negative regulatory element binding&apos; SubClassOf &apos;transcription regulatory region DNA binding&apos;</deletedAxiom>
<deletedAxiom>&apos;purine-rich negative regulatory element binding&apos; SubClassOf &apos;sequence-specific double-stranded DNA binding&apos;</deletedAxiom>
<newAxiom>&apos;purine-rich negative regulatory element binding&apos; SubClassOf &apos;transcription regulatory region sequence-specific DNA binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046932</classIRI>
<classLabel>sodium-transporting ATP synthase activity, rotational mechanism</classLabel>
<deletedAxiom>&apos;sodium-transporting ATP synthase activity, rotational mechanism&apos; SubClassOf &apos;ATPase activity, coupled to transmembrane movement of ions, rotational mechanism&apos;</deletedAxiom>
<deletedAxiom>&apos;sodium-transporting ATP synthase activity, rotational mechanism&apos; SubClassOf &apos;ATPase-coupled cation transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0005006</classIRI>
<classLabel>ionocyte</classLabel>
<newAxiom>'ionocyte' SubClassOf 'epithelial cell'</newAxiom>
<newAxiom>'ionocyte' SubClassOf 'somatic cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106259</classIRI>
<classLabel>cell-to-cell migration in host</classLabel>
<newAxiom>'cell-to-cell migration in host' SubClassOf 'migration in host'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062247</classIRI>
<classLabel>chloroplast vesicle</classLabel>
<newAxiom>'chloroplast vesicle' SubClassOf 'cytoplasmic vesicle'</newAxiom>
<newAxiom>'chloroplast vesicle' SubClassOf 'part of' some 'chloroplast'</newAxiom>
<newAxiom>'chloroplast vesicle' EquivalentTo 'intracellular vesicle' and ('part of' some 'chloroplast')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062246</classIRI>
<classLabel>exocytic vesicle lumen</classLabel>
<newAxiom>'exocytic vesicle lumen' SubClassOf 'transport vesicle lumen'</newAxiom>
<newAxiom>'exocytic vesicle lumen' EquivalentTo 'transport vesicle lumen' and ('part of' some 'exocytic vesicle')</newAxiom>
<newAxiom>'exocytic vesicle lumen' SubClassOf 'part of' some 'exocytic vesicle'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140459</classIRI>
<classLabel>response to Gram-positive bacterium</classLabel>
<newAxiom>'response to Gram-positive bacterium' SubClassOf 'response to bacterium'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140458</classIRI>
<classLabel>pre-transcriptional gene silencing by RNA</classLabel>
<newAxiom>'pre-transcriptional gene silencing by RNA' SubClassOf 'gene silencing by RNA'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140460</classIRI>
<classLabel>response to Gram-negative bacterium</classLabel>
<newAxiom>'response to Gram-negative bacterium' SubClassOf 'response to bacterium'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>