<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
312
</numberChangedClasses>
<numberNewClasses>
33
</numberNewClasses>
<numberDeletedClasses>
1
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010852</classIRI>
<classLabel>cyclase inhibitor activity</classLabel>
<newAxiom>&apos;cyclase inhibitor activity&apos; SubClassOf &apos;enzyme inhibitor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019209</classIRI>
<classLabel>kinase activator activity</classLabel>
<newAxiom>&apos;kinase activator activity&apos; SubClassOf &apos;enzyme activator activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019210</classIRI>
<classLabel>kinase inhibitor activity</classLabel>
<newAxiom>&apos;kinase inhibitor activity&apos; SubClassOf &apos;enzyme inhibitor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019211</classIRI>
<classLabel>phosphatase activator activity</classLabel>
<newAxiom>&apos;phosphatase activator activity&apos; SubClassOf &apos;enzyme activator activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019212</classIRI>
<classLabel>phosphatase inhibitor activity</classLabel>
<newAxiom>&apos;phosphatase inhibitor activity&apos; SubClassOf &apos;enzyme inhibitor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019153</classIRI>
<classLabel>protein-disulfide reductase (glutathione) activity</classLabel>
<newAxiom>&apos;protein-disulfide reductase (glutathione) activity&apos; SubClassOf &apos;protein-disulfide reductase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034724</classIRI>
<classLabel>DNA replication-independent nucleosome organization</classLabel>
<deletedAxiom>&apos;DNA replication-independent nucleosome organization&apos; SubClassOf &apos;chromatin assembly or disassembly&apos;</deletedAxiom>
<deletedAxiom>&apos;DNA replication-independent nucleosome organization&apos; SubClassOf &apos;nucleosome organization&apos;</deletedAxiom>
<newAxiom>&apos;DNA replication-independent nucleosome organization&apos; SubClassOf &apos;chromatin organization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034725</classIRI>
<classLabel>DNA replication-dependent nucleosome disassembly</classLabel>
<deletedAxiom>&apos;DNA replication-dependent nucleosome disassembly&apos; SubClassOf &apos;DNA replication-dependent nucleosome organization&apos;</deletedAxiom>
<deletedAxiom>&apos;DNA replication-dependent nucleosome disassembly&apos; SubClassOf &apos;nucleosome disassembly&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034723</classIRI>
<classLabel>DNA replication-dependent nucleosome organization</classLabel>
<deletedAxiom>&apos;DNA replication-dependent nucleosome organization&apos; SubClassOf &apos;nucleosome organization&apos;</deletedAxiom>
<deletedAxiom>&apos;DNA replication-dependent nucleosome organization&apos; SubClassOf &apos;chromatin assembly or disassembly&apos;</deletedAxiom>
<newAxiom>&apos;DNA replication-dependent nucleosome organization&apos; SubClassOf &apos;chromatin organization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034726</classIRI>
<classLabel>DNA replication-independent nucleosome disassembly</classLabel>
<deletedAxiom>&apos;DNA replication-independent nucleosome disassembly&apos; SubClassOf &apos;DNA replication-independent nucleosome organization&apos;</deletedAxiom>
<deletedAxiom>&apos;DNA replication-independent nucleosome disassembly&apos; SubClassOf &apos;nucleosome disassembly&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002268</classIRI>
<classLabel>olfactory organ</classLabel>
<deletedAxiom>&apos;olfactory organ&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034629</classIRI>
<classLabel>cellular protein-containing complex localization</classLabel>
<deletedAxiom>&apos;cellular protein-containing complex localization&apos; SubClassOf &apos;protein-containing complex localization&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular protein-containing complex localization&apos; SubClassOf &apos;cellular protein localization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034630</classIRI>
<classLabel>RITS complex localization</classLabel>
<deletedAxiom>&apos;RITS complex localization&apos; SubClassOf &apos;cellular protein-containing complex localization&apos;</deletedAxiom>
<newAxiom>&apos;RITS complex localization&apos; SubClassOf &apos;protein-containing complex localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002196</classIRI>
<classLabel>adenohypophysis</classLabel>
<deletedAxiom>&apos;adenohypophysis&apos; SubClassOf &apos;structure with developmental contribution from neural crest&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009508</classIRI>
<classLabel>plastid chromosome</classLabel>
<deletedAxiom>&apos;plastid chromosome&apos; SubClassOf &apos;cytoplasmic chromosome&apos;</deletedAxiom>
<newAxiom>&apos;plastid chromosome&apos; SubClassOf &apos;chromosome&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000985</classIRI>
<classLabel>bacterial-type RNA polymerase core promoter sequence-specific DNA binding</classLabel>
<deletedAxiom>&apos;bacterial-type RNA polymerase core promoter sequence-specific DNA binding&apos; SubClassOf &apos;core promoter sequence-specific DNA binding&apos;</deletedAxiom>
<deletedAxiom>&apos;bacterial-type RNA polymerase core promoter sequence-specific DNA binding&apos; SubClassOf &apos;bacterial-type RNA polymerase transcription regulatory region sequence-specific DNA binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000986</classIRI>
<classLabel>bacterial-type cis-regulatory region sequence-specific DNA binding</classLabel>
<deletedAxiom>&apos;bacterial-type cis-regulatory region sequence-specific DNA binding&apos; SubClassOf &apos;bacterial-type RNA polymerase transcription regulatory region sequence-specific DNA binding&apos;</deletedAxiom>
<deletedAxiom>&apos;bacterial-type cis-regulatory region sequence-specific DNA binding&apos; SubClassOf &apos;cis-regulatory region sequence-specific DNA binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000984</classIRI>
<classLabel>bacterial-type RNA polymerase transcription regulatory region sequence-specific DNA binding</classLabel>
<deletedAxiom>&apos;bacterial-type RNA polymerase transcription regulatory region sequence-specific DNA binding&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Bacteria&apos;</deletedAxiom>
<deletedAxiom>&apos;bacterial-type RNA polymerase transcription regulatory region sequence-specific DNA binding&apos; SubClassOf &apos;in taxon&apos; only &apos;Bacteria&apos;</deletedAxiom>
<deletedAxiom>&apos;bacterial-type RNA polymerase transcription regulatory region sequence-specific DNA binding&apos; SubClassOf &apos;transcription cis-regulatory region binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000809</classIRI>
<classLabel>cytoplasmic origin of replication recognition complex</classLabel>
<deletedAxiom>&apos;cytoplasmic origin of replication recognition complex&apos; SubClassOf &apos;part of&apos; some &apos;cytoplasmic chromosome&apos;</deletedAxiom>
<newAxiom>&apos;cytoplasmic origin of replication recognition complex&apos; SubClassOf &apos;part of&apos; some &apos;cytoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010112</classIRI>
<classLabel>regulation of systemic acquired resistance</classLabel>
<deletedAxiom>&apos;regulation of systemic acquired resistance&apos; SubClassOf &apos;regulation of immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010113</classIRI>
<classLabel>negative regulation of systemic acquired resistance</classLabel>
<deletedAxiom>&apos;negative regulation of systemic acquired resistance&apos; SubClassOf &apos;negative regulation of immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002511</classIRI>
<classLabel>trabecula carnea</classLabel>
<deletedAxiom>&apos;trabecula carnea&apos; SubClassOf &apos;structure with developmental contribution from neural crest&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097638</classIRI>
<classLabel>L-arginine import across plasma membrane</classLabel>
<deletedAxiom>&apos;L-arginine import across plasma membrane&apos; SubClassOf &apos;L-arginine transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;L-arginine import across plasma membrane&apos; SubClassOf &apos;L-alpha-amino acid transmembrane transport&apos;</newAxiom>
<newAxiom>&apos;L-arginine import across plasma membrane&apos; SubClassOf &apos;cation transmembrane transport&apos;</newAxiom>
<newAxiom>&apos;L-arginine import across plasma membrane&apos; SubClassOf &apos;L-amino acid transport&apos;</newAxiom>
<newAxiom>&apos;L-arginine import across plasma membrane&apos; SubClassOf &apos;anion transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097626</classIRI>
<classLabel>low-affinity L-arginine transmembrane transporter activity</classLabel>
<newAxiom>&apos;low-affinity L-arginine transmembrane transporter activity&apos; EquivalentTo &apos;low-affinity basic amino acid transmembrane transporter activity&apos; and (&apos;transports or maintains localization of&apos; some &apos;L-argininium(1+)&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009098</classIRI>
<classLabel>leucine biosynthetic process</classLabel>
<deletedAxiom>&apos;leucine biosynthetic process&apos; SubClassOf &apos;cellular amino acid biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;leucine biosynthetic process&apos; SubClassOf &apos;has primary output&apos; some &apos;leucinate&apos;</deletedAxiom>
<deletedAxiom>&apos;leucine biosynthetic process&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some &apos;leucinate&apos;)</deletedAxiom>
<newAxiom>&apos;leucine biosynthetic process&apos; SubClassOf &apos;branched-chain amino acid biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;leucine biosynthetic process&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some &apos;leucine&apos;)</newAxiom>
<newAxiom>&apos;leucine biosynthetic process&apos; SubClassOf &apos;alpha-amino acid biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;leucine biosynthetic process&apos; SubClassOf &apos;has primary output&apos; some &apos;leucine&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009099</classIRI>
<classLabel>valine biosynthetic process</classLabel>
<deletedAxiom>&apos;valine biosynthetic process&apos; SubClassOf &apos;cellular amino acid biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;valine biosynthetic process&apos; SubClassOf &apos;has primary output&apos; some &apos;valinate&apos;</deletedAxiom>
<deletedAxiom>&apos;valine biosynthetic process&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some &apos;valinate&apos;)</deletedAxiom>
<newAxiom>&apos;valine biosynthetic process&apos; SubClassOf &apos;alpha-amino acid biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;valine biosynthetic process&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some &apos;valine&apos;)</newAxiom>
<newAxiom>&apos;valine biosynthetic process&apos; SubClassOf &apos;branched-chain amino acid biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;valine biosynthetic process&apos; SubClassOf &apos;has primary output&apos; some &apos;valine&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034080</classIRI>
<classLabel>CENP-A containing nucleosome assembly</classLabel>
<newAxiom>&apos;CENP-A containing nucleosome assembly&apos; SubClassOf &apos;nucleosome assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000395</classIRI>
<classLabel>regulation of ubiquitin-dependent endocytosis</classLabel>
<deletedAxiom>&apos;regulation of ubiquitin-dependent endocytosis&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of ubiquitin-dependent endocytosis&apos; SubClassOf &apos;regulation of cellular localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000396</classIRI>
<classLabel>negative regulation of ubiquitin-dependent endocytosis</classLabel>
<deletedAxiom>&apos;negative regulation of ubiquitin-dependent endocytosis&apos; SubClassOf &apos;negative regulation of cellular protein localization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000397</classIRI>
<classLabel>positive regulation of ubiquitin-dependent endocytosis</classLabel>
<deletedAxiom>&apos;positive regulation of ubiquitin-dependent endocytosis&apos; SubClassOf &apos;positive regulation of cellular protein localization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000262</classIRI>
<classLabel>mitochondrial chromosome</classLabel>
<deletedAxiom>&apos;mitochondrial chromosome&apos; SubClassOf &apos;cytoplasmic chromosome&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial chromosome&apos; SubClassOf &apos;chromosome&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000229</classIRI>
<classLabel>cytoplasmic chromosome</classLabel>
<deletedAxiom>&apos;cytoplasmic chromosome&apos; EquivalentTo &apos;chromosome&apos; and (&apos;part of&apos; some &apos;cytoplasm&apos;)</deletedAxiom>
<deletedAxiom>&apos;cytoplasmic chromosome&apos; SubClassOf &apos;chromosome&apos;</deletedAxiom>
<deletedAxiom>&apos;cytoplasmic chromosome&apos; SubClassOf &apos;part of&apos; some &apos;cytoplasm&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000172</classIRI>
<classLabel>ribonuclease MRP complex</classLabel>
<deletedAxiom>&apos;ribonuclease MRP complex&apos; SubClassOf &apos;catalytic complex&apos;</deletedAxiom>
<newAxiom>&apos;ribonuclease MRP complex&apos; SubClassOf &apos;endoribonuclease complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000171</classIRI>
<classLabel>ribonuclease MRP activity</classLabel>
<deletedAxiom>&apos;ribonuclease MRP activity&apos; SubClassOf &apos;ribonuclease activity&apos;</deletedAxiom>
<newAxiom>&apos;ribonuclease MRP activity&apos; SubClassOf &apos;endoribonuclease activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048096</classIRI>
<classLabel>chromatin-mediated maintenance of transcription</classLabel>
<deletedAxiom>&apos;chromatin-mediated maintenance of transcription&apos; SubClassOf &apos;positive regulation of transcription, DNA-templated&apos;</deletedAxiom>
<deletedAxiom>&apos;chromatin-mediated maintenance of transcription&apos; SubClassOf &apos;positive regulation of gene expression, epigenetic&apos;</deletedAxiom>
<deletedAxiom>&apos;chromatin-mediated maintenance of transcription&apos; SubClassOf &apos;part of&apos; some &apos;transcription elongation from RNA polymerase II promoter&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097027</classIRI>
<classLabel>ubiquitin-protein transferase activator activity</classLabel>
<newAxiom>&apos;ubiquitin-protein transferase activator activity&apos; SubClassOf &apos;enzyme activator activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990299</classIRI>
<classLabel>Bub1-Bub3 complex localization to kinetochore</classLabel>
<deletedAxiom>&apos;Bub1-Bub3 complex localization to kinetochore&apos; SubClassOf &apos;cellular protein-containing complex localization&apos;</deletedAxiom>
<newAxiom>&apos;Bub1-Bub3 complex localization to kinetochore&apos; SubClassOf &apos;protein-containing complex localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990257</classIRI>
<classLabel>piccolo-bassoon transport vesicle</classLabel>
<deletedAxiom>&apos;piccolo-bassoon transport vesicle&apos; DisjointWith &apos;in taxon&apos; some &apos;Schizosaccharomyces&apos;</deletedAxiom>
<deletedAxiom>&apos;piccolo-bassoon transport vesicle&apos; SubClassOf &apos;cytoplasmic vesicle&apos;</deletedAxiom>
<deletedAxiom>&apos;piccolo-bassoon transport vesicle&apos; SubClassOf not (&apos;in taxon&apos; some &apos;Schizosaccharomyces&apos;)</deletedAxiom>
<newAxiom>&apos;piccolo-bassoon transport vesicle&apos; SubClassOf &apos;in taxon&apos; only &apos;Eumetazoa&apos;</newAxiom>
<newAxiom>&apos;piccolo-bassoon transport vesicle&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eumetazoa&apos;</newAxiom>
<newAxiom>&apos;piccolo-bassoon transport vesicle&apos; SubClassOf &apos;part of&apos; some &apos;neuron&apos;</newAxiom>
<newAxiom>&apos;piccolo-bassoon transport vesicle&apos; SubClassOf &apos;transport vesicle&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000048</classIRI>
<classLabel>peptidyltransferase activity</classLabel>
<deletedAxiom>&apos;peptidyltransferase activity&apos; SubClassOf &apos;part of&apos; some &apos;translation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0022320</classIRI>
<classLabel>dorsal cochlear nucleus pyramidal cell layer</classLabel>
<deletedAxiom>&apos;dorsal cochlear nucleus pyramidal cell layer&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_6002639</classIRI>
<classLabel>insect larval sense organ</classLabel>
<deletedAxiom>&apos;insect larval sense organ&apos; EquivalentTo &apos;sense organ&apos; and (&apos;part of&apos; some &apos;larva&apos;)</deletedAxiom>
<newAxiom>&apos;insect larval sense organ&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Insecta&apos;</newAxiom>
<newAxiom>&apos;insect larval sense organ&apos; EquivalentTo &apos;sense organ&apos; and (&apos;part of&apos; some &apos;larva&apos;) and (&apos;only_in_taxon&apos; some &apos;Insecta&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905783</classIRI>
<classLabel>CENP-A containing nucleosome disassembly</classLabel>
<deletedAxiom>&apos;CENP-A containing nucleosome disassembly&apos; SubClassOf &apos;results in disassembly of&apos; some &apos;CENP-A containing nucleosome&apos;</deletedAxiom>
<deletedAxiom>&apos;CENP-A containing nucleosome disassembly&apos; EquivalentTo &apos;cellular component disassembly&apos; and (&apos;results in disassembly of&apos; some &apos;CENP-A containing nucleosome&apos;)</deletedAxiom>
<deletedAxiom>&apos;CENP-A containing nucleosome disassembly&apos; SubClassOf &apos;nucleosome disassembly&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905871</classIRI>
<classLabel>regulation of protein localization to cell leading edge</classLabel>
<deletedAxiom>&apos;regulation of protein localization to cell leading edge&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of protein localization to cell leading edge&apos; SubClassOf &apos;regulation of protein localization&apos;</newAxiom>
<newAxiom>&apos;regulation of protein localization to cell leading edge&apos; SubClassOf &apos;regulation of cellular localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905872</classIRI>
<classLabel>negative regulation of protein localization to cell leading edge</classLabel>
<newAxiom>&apos;negative regulation of protein localization to cell leading edge&apos; SubClassOf &apos;negative regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905873</classIRI>
<classLabel>positive regulation of protein localization to cell leading edge</classLabel>
<newAxiom>&apos;positive regulation of protein localization to cell leading edge&apos; SubClassOf &apos;positive regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004857</classIRI>
<classLabel>enzyme inhibitor activity</classLabel>
<deletedAxiom>&apos;enzyme inhibitor activity&apos; SubClassOf &apos;molecular function inhibitor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;enzyme inhibitor activity&apos; EquivalentTo &apos;molecular function inhibitor activity&apos; and (&apos;negatively regulates&apos; some &apos;catalytic activity&apos;)</deletedAxiom>
<newAxiom>&apos;enzyme inhibitor activity&apos; EquivalentTo &apos;molecular function regulator&apos; and (&apos;negatively regulates&apos; some &apos;catalytic activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901217</classIRI>
<classLabel>regulation of holin activity</classLabel>
<deletedAxiom>&apos;regulation of holin activity&apos; SubClassOf &apos;regulation of viral release from host cell&apos;</deletedAxiom>
<newAxiom>&apos;regulation of holin activity&apos; SubClassOf &apos;regulates&apos; some &apos;viral release from host cell&apos;</newAxiom>
<newAxiom>&apos;regulation of holin activity&apos; SubClassOf &apos;regulation of viral process&apos;</newAxiom>
<newAxiom>&apos;regulation of holin activity&apos; SubClassOf &apos;regulation of biological process involved in symbiotic interaction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901218</classIRI>
<classLabel>negative regulation of holin activity</classLabel>
<deletedAxiom>&apos;negative regulation of holin activity&apos; SubClassOf &apos;negative regulation of viral release from host cell&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of holin activity&apos; SubClassOf &apos;negatively regulates&apos; some &apos;viral release from host cell&apos;</newAxiom>
<newAxiom>&apos;negative regulation of holin activity&apos; SubClassOf &apos;negative regulation of viral process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000068</classIRI>
<classLabel>regulation of defense response to insect</classLabel>
<deletedAxiom>&apos;regulation of defense response to insect&apos; SubClassOf &apos;regulation of immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000008</classIRI>
<classLabel>regulation of protein localization to cell surface</classLabel>
<deletedAxiom>&apos;regulation of protein localization to cell surface&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of protein localization to cell surface&apos; SubClassOf &apos;regulation of cellular localization&apos;</newAxiom>
<newAxiom>&apos;regulation of protein localization to cell surface&apos; SubClassOf &apos;regulation of protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000009</classIRI>
<classLabel>negative regulation of protein localization to cell surface</classLabel>
<newAxiom>&apos;negative regulation of protein localization to cell surface&apos; SubClassOf &apos;negative regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000010</classIRI>
<classLabel>positive regulation of protein localization to cell surface</classLabel>
<newAxiom>&apos;positive regulation of protein localization to cell surface&apos; SubClassOf &apos;positive regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043862</classIRI>
<classLabel>arginine:agmatine antiporter activity</classLabel>
<deletedAxiom>&apos;arginine:agmatine antiporter activity&apos; SubClassOf &apos;arginine transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;arginine:agmatine antiporter activity&apos; SubClassOf &apos;amino acid transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;arginine:agmatine antiporter activity&apos; SubClassOf &apos;organic anion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043858</classIRI>
<classLabel>arginine:ornithine antiporter activity</classLabel>
<deletedAxiom>&apos;arginine:ornithine antiporter activity&apos; SubClassOf &apos;arginine transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;arginine:ornithine antiporter activity&apos; SubClassOf &apos;amino acid transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;arginine:ornithine antiporter activity&apos; SubClassOf &apos;organic anion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_4000020</classIRI>
<classLabel>mineralized extracellular matrix</classLabel>
<deletedAxiom>&apos;mineralized extracellular matrix&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0005578</deletedAxiom>
<newAxiom>&apos;mineralized extracellular matrix&apos; SubClassOf &apos;extracellular matrix&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901672</classIRI>
<classLabel>positive regulation of systemic acquired resistance</classLabel>
<deletedAxiom>&apos;positive regulation of systemic acquired resistance&apos; SubClassOf &apos;positive regulation of immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043597</classIRI>
<classLabel>cytoplasmic replication fork</classLabel>
<deletedAxiom>&apos;cytoplasmic replication fork&apos; SubClassOf &apos;part of&apos; some &apos;cytoplasmic chromosome&apos;</deletedAxiom>
<newAxiom>&apos;cytoplasmic replication fork&apos; SubClassOf &apos;part of&apos; some &apos;cytoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901900</classIRI>
<classLabel>regulation of protein localization to cell division site</classLabel>
<deletedAxiom>&apos;regulation of protein localization to cell division site&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of protein localization to cell division site&apos; SubClassOf &apos;regulation of protein localization&apos;</newAxiom>
<newAxiom>&apos;regulation of protein localization to cell division site&apos; SubClassOf &apos;regulation of cellular localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043137</classIRI>
<classLabel>DNA replication, removal of RNA primer</classLabel>
<deletedAxiom>&apos;DNA replication, removal of RNA primer&apos; SubClassOf &apos;DNA metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;DNA replication, removal of RNA primer&apos; SubClassOf &apos;part of&apos; some &apos;DNA replication&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033751</classIRI>
<classLabel>linoleate 8R-lipoxygenase</classLabel>
<deletedAxiom>&apos;linoleate 8R-lipoxygenase&apos; SubClassOf &apos;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060967</classIRI>
<classLabel>negative regulation of gene silencing by RNA</classLabel>
<deletedAxiom>&apos;negative regulation of gene silencing by RNA&apos; SubClassOf &apos;negative regulation of gene silencing&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of gene silencing by RNA&apos; SubClassOf &apos;negative regulation of biological process&apos;</newAxiom>
<newAxiom>&apos;negative regulation of gene silencing by RNA&apos; SubClassOf &apos;positive regulation of gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060968</classIRI>
<classLabel>regulation of gene silencing</classLabel>
<deletedAxiom>&apos;regulation of gene silencing&apos; SubClassOf &apos;regulation of gene expression&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of gene silencing&apos; SubClassOf &apos;regulates&apos; some &apos;gene silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of gene silencing&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;gene silencing&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060966</classIRI>
<classLabel>regulation of gene silencing by RNA</classLabel>
<deletedAxiom>&apos;regulation of gene silencing by RNA&apos; SubClassOf &apos;regulation of gene silencing&apos;</deletedAxiom>
<newAxiom>&apos;regulation of gene silencing by RNA&apos; SubClassOf &apos;regulation of gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060969</classIRI>
<classLabel>negative regulation of gene silencing</classLabel>
<deletedAxiom>&apos;negative regulation of gene silencing&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;gene silencing&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of gene silencing&apos; SubClassOf &apos;negative regulation of biological process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of gene silencing&apos; SubClassOf &apos;positive regulation of gene expression&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of gene silencing&apos; SubClassOf &apos;regulation of gene silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of gene silencing&apos; SubClassOf &apos;negatively regulates&apos; some &apos;gene silencing&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070202</classIRI>
<classLabel>regulation of establishment of protein localization to chromosome</classLabel>
<deletedAxiom>&apos;regulation of establishment of protein localization to chromosome&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of establishment of protein localization to chromosome&apos; SubClassOf &apos;regulation of cellular localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035853</classIRI>
<classLabel>chromosome passenger complex localization to spindle midzone</classLabel>
<deletedAxiom>&apos;chromosome passenger complex localization to spindle midzone&apos; SubClassOf &apos;cellular protein-containing complex localization&apos;</deletedAxiom>
<newAxiom>&apos;chromosome passenger complex localization to spindle midzone&apos; SubClassOf &apos;protein-containing complex localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045010</classIRI>
<classLabel>actin nucleation</classLabel>
<deletedAxiom>&apos;actin nucleation&apos; SubClassOf &apos;positive regulation of actin filament polymerization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045087</classIRI>
<classLabel>innate immune response</classLabel>
<newAxiom>&apos;innate immune response&apos; SubClassOf &apos;immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_6003006</classIRI>
<classLabel>adult segment</classLabel>
<deletedAxiom>&apos;adult segment&apos; EquivalentTo &apos;organismal segment&apos; and (&apos;part of&apos; some &apos;adult organism&apos;)</deletedAxiom>
<newAxiom>&apos;adult segment&apos; EquivalentTo &apos;organismal segment&apos; and (&apos;part of&apos; some &apos;adult organism&apos;) and (&apos;only_in_taxon&apos; some &apos;Insecta&apos;)</newAxiom>
<newAxiom>&apos;adult segment&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Insecta&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905099</classIRI>
<classLabel>positive regulation of guanyl-nucleotide exchange factor activity</classLabel>
<deletedAxiom>&apos;positive regulation of guanyl-nucleotide exchange factor activity&apos; SubClassOf &apos;positive regulation of GTPase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035279</classIRI>
<classLabel>mRNA cleavage involved in gene silencing by miRNA</classLabel>
<deletedAxiom>&apos;mRNA cleavage involved in gene silencing by miRNA&apos; SubClassOf &apos;mRNA cleavage involved in gene silencing&apos;</deletedAxiom>
<newAxiom>&apos;mRNA cleavage involved in gene silencing by miRNA&apos; SubClassOf &apos;mRNA cleavage&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060149</classIRI>
<classLabel>negative regulation of posttranscriptional gene silencing</classLabel>
<deletedAxiom>&apos;negative regulation of posttranscriptional gene silencing&apos; SubClassOf &apos;negative regulation of gene silencing&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of posttranscriptional gene silencing&apos; SubClassOf &apos;negative regulation of biological process&apos;</newAxiom>
<newAxiom>&apos;negative regulation of posttranscriptional gene silencing&apos; SubClassOf &apos;positive regulation of gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060147</classIRI>
<classLabel>regulation of posttranscriptional gene silencing</classLabel>
<deletedAxiom>&apos;regulation of posttranscriptional gene silencing&apos; SubClassOf &apos;regulation of gene silencing&apos;</deletedAxiom>
<newAxiom>&apos;regulation of posttranscriptional gene silencing&apos; SubClassOf &apos;regulation of gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098795</classIRI>
<classLabel>mRNA cleavage involved in gene silencing</classLabel>
<deletedAxiom>&apos;mRNA cleavage involved in gene silencing&apos; EquivalentTo &apos;mRNA cleavage&apos; and (&apos;part of&apos; some &apos;gene silencing&apos;)</deletedAxiom>
<deletedAxiom>&apos;mRNA cleavage involved in gene silencing&apos; SubClassOf &apos;part of&apos; some &apos;gene silencing&apos;</deletedAxiom>
<newAxiom>&apos;mRNA cleavage involved in gene silencing&apos; SubClassOf &apos;negative regulation of gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060178</classIRI>
<classLabel>regulation of exocyst localization</classLabel>
<deletedAxiom>&apos;regulation of exocyst localization&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of exocyst localization&apos; SubClassOf &apos;regulation of localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905170</classIRI>
<classLabel>negative regulation of protein localization to phagocytic vesicle</classLabel>
<newAxiom>&apos;negative regulation of protein localization to phagocytic vesicle&apos; SubClassOf &apos;negative regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905171</classIRI>
<classLabel>positive regulation of protein localization to phagocytic vesicle</classLabel>
<newAxiom>&apos;positive regulation of protein localization to phagocytic vesicle&apos; SubClassOf &apos;positive regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905169</classIRI>
<classLabel>regulation of protein localization to phagocytic vesicle</classLabel>
<deletedAxiom>&apos;regulation of protein localization to phagocytic vesicle&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of protein localization to phagocytic vesicle&apos; SubClassOf &apos;regulation of cellular localization&apos;</newAxiom>
<newAxiom>&apos;regulation of protein localization to phagocytic vesicle&apos; SubClassOf &apos;regulation of protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098713</classIRI>
<classLabel>leucine import across plasma membrane</classLabel>
<deletedAxiom>&apos;leucine import across plasma membrane&apos; SubClassOf &apos;branched-chain amino acid transport&apos;</deletedAxiom>
<newAxiom>&apos;leucine import across plasma membrane&apos; SubClassOf &apos;leucine transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050687</classIRI>
<classLabel>negative regulation of defense response to virus</classLabel>
<deletedAxiom>&apos;negative regulation of defense response to virus&apos; SubClassOf &apos;negative regulation of immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050688</classIRI>
<classLabel>regulation of defense response to virus</classLabel>
<deletedAxiom>&apos;regulation of defense response to virus&apos; SubClassOf &apos;regulation of immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098542</classIRI>
<classLabel>defense response to other organism</classLabel>
<deletedAxiom>&apos;defense response to other organism&apos; SubClassOf &apos;immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001747</classIRI>
<classLabel>parenchyma of thyroid gland</classLabel>
<deletedAxiom>&apos;parenchyma of thyroid gland&apos; SubClassOf &apos;structure with developmental contribution from neural crest&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905342</classIRI>
<classLabel>positive regulation of protein localization to kinetochore</classLabel>
<newAxiom>&apos;positive regulation of protein localization to kinetochore&apos; SubClassOf &apos;positive regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905340</classIRI>
<classLabel>regulation of protein localization to kinetochore</classLabel>
<deletedAxiom>&apos;regulation of protein localization to kinetochore&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of protein localization to kinetochore&apos; SubClassOf &apos;regulation of cellular localization&apos;</newAxiom>
<newAxiom>&apos;regulation of protein localization to kinetochore&apos; SubClassOf &apos;regulation of protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905341</classIRI>
<classLabel>negative regulation of protein localization to kinetochore</classLabel>
<newAxiom>&apos;negative regulation of protein localization to kinetochore&apos; SubClassOf &apos;negative regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905385</classIRI>
<classLabel>negative regulation of protein localization to presynapse</classLabel>
<deletedAxiom>&apos;negative regulation of protein localization to presynapse&apos; SubClassOf &apos;negative regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of protein localization to presynapse&apos; SubClassOf &apos;negative regulation of cellular protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905475</classIRI>
<classLabel>regulation of protein localization to membrane</classLabel>
<deletedAxiom>&apos;regulation of protein localization to membrane&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of protein localization to membrane&apos; SubClassOf &apos;regulation of cellular localization&apos;</newAxiom>
<newAxiom>&apos;regulation of protein localization to membrane&apos; SubClassOf &apos;regulation of protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905476</classIRI>
<classLabel>negative regulation of protein localization to membrane</classLabel>
<newAxiom>&apos;negative regulation of protein localization to membrane&apos; SubClassOf &apos;negative regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905477</classIRI>
<classLabel>positive regulation of protein localization to membrane</classLabel>
<newAxiom>&apos;positive regulation of protein localization to membrane&apos; SubClassOf &apos;positive regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905541</classIRI>
<classLabel>regulation of L-arginine import across plasma membrane</classLabel>
<deletedAxiom>&apos;regulation of L-arginine import across plasma membrane&apos; SubClassOf &apos;regulation of L-arginine import&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905551</classIRI>
<classLabel>negative regulation of protein localization to endoplasmic reticulum</classLabel>
<newAxiom>&apos;negative regulation of protein localization to endoplasmic reticulum&apos; SubClassOf &apos;negative regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905552</classIRI>
<classLabel>positive regulation of protein localization to endoplasmic reticulum</classLabel>
<newAxiom>&apos;positive regulation of protein localization to endoplasmic reticulum&apos; SubClassOf &apos;positive regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905550</classIRI>
<classLabel>regulation of protein localization to endoplasmic reticulum</classLabel>
<deletedAxiom>&apos;regulation of protein localization to endoplasmic reticulum&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of protein localization to endoplasmic reticulum&apos; SubClassOf &apos;regulation of protein localization&apos;</newAxiom>
<newAxiom>&apos;regulation of protein localization to endoplasmic reticulum&apos; SubClassOf &apos;regulation of cellular localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015809</classIRI>
<classLabel>arginine transport</classLabel>
<deletedAxiom>&apos;arginine transport&apos; SubClassOf &apos;basic amino acid transport&apos;</deletedAxiom>
<deletedAxiom>&apos;arginine transport&apos; EquivalentTo &apos;basic amino acid transport&apos; and (&apos;transports or maintains localization of&apos; some &apos;argininium(1+)&apos;)</deletedAxiom>
<deletedAxiom>&apos;arginine transport&apos; SubClassOf &apos;carboxylic acid transport&apos;</deletedAxiom>
<deletedAxiom>&apos;arginine transport&apos; SubClassOf &apos;transports or maintains localization of&apos; some &apos;argininium(1+)&apos;</deletedAxiom>
<deletedAxiom>&apos;arginine transport&apos; SubClassOf &apos;cation transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015820</classIRI>
<classLabel>leucine transport</classLabel>
<deletedAxiom>&apos;leucine transport&apos; SubClassOf &apos;transports or maintains localization of&apos; some &apos;leucinate&apos;</deletedAxiom>
<deletedAxiom>&apos;leucine transport&apos; SubClassOf &apos;carboxylic acid transport&apos;</deletedAxiom>
<deletedAxiom>&apos;leucine transport&apos; EquivalentTo &apos;transport&apos; and (&apos;transports or maintains localization of&apos; some &apos;leucinate&apos;)</deletedAxiom>
<newAxiom>&apos;leucine transport&apos; EquivalentTo &apos;transport&apos; and (&apos;transports or maintains localization of&apos; some &apos;leucine&apos;)</newAxiom>
<newAxiom>&apos;leucine transport&apos; SubClassOf &apos;transports or maintains localization of&apos; some &apos;leucine&apos;</newAxiom>
<newAxiom>&apos;leucine transport&apos; SubClassOf &apos;branched-chain amino acid transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015829</classIRI>
<classLabel>valine transport</classLabel>
<deletedAxiom>&apos;valine transport&apos; EquivalentTo &apos;transport&apos; and (&apos;transports or maintains localization of&apos; some &apos;valinate&apos;)</deletedAxiom>
<deletedAxiom>&apos;valine transport&apos; SubClassOf &apos;carboxylic acid transport&apos;</deletedAxiom>
<deletedAxiom>&apos;valine transport&apos; SubClassOf &apos;transports or maintains localization of&apos; some &apos;valinate&apos;</deletedAxiom>
<newAxiom>&apos;valine transport&apos; EquivalentTo &apos;transport&apos; and (&apos;transports or maintains localization of&apos; some &apos;valine&apos;)</newAxiom>
<newAxiom>&apos;valine transport&apos; SubClassOf &apos;transports or maintains localization of&apos; some &apos;valine&apos;</newAxiom>
<newAxiom>&apos;valine transport&apos; SubClassOf &apos;branched-chain amino acid transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001194</classIRI>
<classLabel>maintenance of transcriptional fidelity during DNA-templated transcription elongation from bacterial-type RNA polymerase promoter</classLabel>
<deletedAxiom>&apos;maintenance of transcriptional fidelity during DNA-templated transcription elongation from bacterial-type RNA polymerase promoter&apos; SubClassOf &apos;part of&apos; some &apos;transcription elongation from bacterial-type RNA polymerase promoter&apos;</deletedAxiom>
<deletedAxiom>&apos;maintenance of transcriptional fidelity during DNA-templated transcription elongation from bacterial-type RNA polymerase promoter&apos; SubClassOf &apos;maintenance of transcriptional fidelity during DNA-templated transcription elongation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905666</classIRI>
<classLabel>regulation of protein localization to endosome</classLabel>
<deletedAxiom>&apos;regulation of protein localization to endosome&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of protein localization to endosome&apos; SubClassOf &apos;regulation of cellular localization&apos;</newAxiom>
<newAxiom>&apos;regulation of protein localization to endosome&apos; SubClassOf &apos;regulation of protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905667</classIRI>
<classLabel>negative regulation of protein localization to endosome</classLabel>
<newAxiom>&apos;negative regulation of protein localization to endosome&apos; SubClassOf &apos;negative regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905668</classIRI>
<classLabel>positive regulation of protein localization to endosome</classLabel>
<newAxiom>&apos;positive regulation of protein localization to endosome&apos; SubClassOf &apos;positive regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905634</classIRI>
<classLabel>regulation of protein localization to chromatin</classLabel>
<deletedAxiom>&apos;regulation of protein localization to chromatin&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of protein localization to chromatin&apos; SubClassOf &apos;regulation of protein localization&apos;</newAxiom>
<newAxiom>&apos;regulation of protein localization to chromatin&apos; SubClassOf &apos;regulation of cellular localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001176</classIRI>
<classLabel>transcriptional start site selection at bacterial-type RNA polymerase promoter</classLabel>
<deletedAxiom>&apos;transcriptional start site selection at bacterial-type RNA polymerase promoter&apos; SubClassOf &apos;DNA-templated transcriptional start site selection&apos;</deletedAxiom>
<deletedAxiom>&apos;transcriptional start site selection at bacterial-type RNA polymerase promoter&apos; SubClassOf &apos;part of&apos; some &apos;transcription initiation from bacterial-type RNA polymerase promoter&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001126</classIRI>
<classLabel>bacterial-type RNA polymerase preinitiation complex assembly</classLabel>
<deletedAxiom>&apos;bacterial-type RNA polymerase preinitiation complex assembly&apos; SubClassOf &apos;part of&apos; some &apos;transcription initiation from bacterial-type RNA polymerase promoter&apos;</deletedAxiom>
<deletedAxiom>&apos;bacterial-type RNA polymerase preinitiation complex assembly&apos; SubClassOf &apos;transcription preinitiation complex assembly&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001127</classIRI>
<classLabel>transcription open complex formation at bacterial-type RNA polymerase promoter</classLabel>
<deletedAxiom>&apos;transcription open complex formation at bacterial-type RNA polymerase promoter&apos; SubClassOf &apos;DNA-templated transcription open complex formation&apos;</deletedAxiom>
<deletedAxiom>&apos;transcription open complex formation at bacterial-type RNA polymerase promoter&apos; SubClassOf &apos;part of&apos; some &apos;transcription initiation from bacterial-type RNA polymerase promoter&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001124</classIRI>
<classLabel>transcription elongation from bacterial-type RNA polymerase promoter</classLabel>
<deletedAxiom>&apos;transcription elongation from bacterial-type RNA polymerase promoter&apos; SubClassOf &apos;part of&apos; some &apos;bacterial transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;transcription elongation from bacterial-type RNA polymerase promoter&apos; SubClassOf &apos;DNA-templated transcription, elongation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001125</classIRI>
<classLabel>transcription termination from bacterial-type RNA polymerase promoter</classLabel>
<deletedAxiom>&apos;transcription termination from bacterial-type RNA polymerase promoter&apos; SubClassOf &apos;part of&apos; some &apos;bacterial transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;transcription termination from bacterial-type RNA polymerase promoter&apos; SubClassOf &apos;DNA-templated transcription, termination&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001122</classIRI>
<classLabel>promoter clearance from bacterial-type RNA polymerase promoter</classLabel>
<deletedAxiom>&apos;promoter clearance from bacterial-type RNA polymerase promoter&apos; SubClassOf &apos;part of&apos; some &apos;bacterial transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;promoter clearance from bacterial-type RNA polymerase promoter&apos; SubClassOf &apos;promoter clearance during DNA-templated transcription&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001123</classIRI>
<classLabel>transcription initiation from bacterial-type RNA polymerase promoter</classLabel>
<deletedAxiom>&apos;transcription initiation from bacterial-type RNA polymerase promoter&apos; SubClassOf &apos;DNA-templated transcription, initiation&apos;</deletedAxiom>
<deletedAxiom>&apos;transcription initiation from bacterial-type RNA polymerase promoter&apos; SubClassOf &apos;part of&apos; some &apos;bacterial transcription&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001121</classIRI>
<classLabel>bacterial transcription</classLabel>
<deletedAxiom>&apos;bacterial transcription&apos; SubClassOf &apos;in taxon&apos; only &apos;Bacteria&apos;</deletedAxiom>
<deletedAxiom>&apos;bacterial transcription&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Bacteria&apos;</deletedAxiom>
<deletedAxiom>&apos;bacterial transcription&apos; SubClassOf &apos;transcription, DNA-templated&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039652</classIRI>
<classLabel>activation by virus of host NF-kappaB transcription factor activity</classLabel>
<deletedAxiom>&apos;activation by virus of host NF-kappaB transcription factor activity&apos; SubClassOf &apos;regulation of molecular function&apos;</deletedAxiom>
<deletedAxiom>&apos;activation by virus of host NF-kappaB transcription factor activity&apos; SubClassOf &apos;modulation by virus of host molecular function&apos;</deletedAxiom>
<deletedAxiom>&apos;activation by virus of host NF-kappaB transcription factor activity&apos; SubClassOf &apos;modulation by virus of host transcription&apos;</deletedAxiom>
<newAxiom>&apos;activation by virus of host NF-kappaB transcription factor activity&apos; SubClassOf &apos;modulation by virus of host cellular process&apos;</newAxiom>
<newAxiom>&apos;activation by virus of host NF-kappaB transcription factor activity&apos; SubClassOf &apos;induction by symbiont of host I-kappaB kinase/NF-kappaB cascade&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039647</classIRI>
<classLabel>suppression by virus of host poly(A)-binding protein activity</classLabel>
<deletedAxiom>&apos;suppression by virus of host poly(A)-binding protein activity&apos; SubClassOf &apos;suppression by virus of host translation&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host poly(A)-binding protein activity&apos; SubClassOf &apos;suppression by virus of host molecular function&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039644</classIRI>
<classLabel>suppression by virus of host NF-kappaB transcription factor activity</classLabel>
<deletedAxiom>&apos;suppression by virus of host NF-kappaB transcription factor activity&apos; SubClassOf &apos;suppression by virus of host molecular function&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host NF-kappaB transcription factor activity&apos; SubClassOf &apos;suppression by virus of host transcription&apos;</deletedAxiom>
<newAxiom>&apos;suppression by virus of host NF-kappaB transcription factor activity&apos; SubClassOf &apos;mitigation of host defenses by virus&apos;</newAxiom>
<newAxiom>&apos;suppression by virus of host NF-kappaB transcription factor activity&apos; SubClassOf &apos;modulation by virus of host cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015696</classIRI>
<classLabel>ammonium transport</classLabel>
<deletedAxiom>&apos;ammonium transport&apos; SubClassOf &apos;transports or maintains localization of&apos; some &apos;ammonium&apos;</deletedAxiom>
<deletedAxiom>&apos;ammonium transport&apos; SubClassOf &apos;cation transport&apos;</deletedAxiom>
<deletedAxiom>&apos;ammonium transport&apos; SubClassOf &apos;nitrogen compound transport&apos;</deletedAxiom>
<deletedAxiom>&apos;ammonium transport&apos; EquivalentTo &apos;transport&apos; and (&apos;transports or maintains localization of&apos; some &apos;ammonium&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039579</classIRI>
<classLabel>suppression by virus of host ISG15 activity</classLabel>
<deletedAxiom>&apos;suppression by virus of host ISG15 activity&apos; SubClassOf &apos;suppression by virus of host molecular function&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039591</classIRI>
<classLabel>suppression by virus of host tapasin activity</classLabel>
<deletedAxiom>&apos;suppression by virus of host tapasin activity&apos; SubClassOf &apos;suppression by virus of host molecular function&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host tapasin activity&apos; SubClassOf &apos;suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039587</classIRI>
<classLabel>suppression by virus of host tetherin activity</classLabel>
<deletedAxiom>&apos;suppression by virus of host tetherin activity&apos; SubClassOf &apos;modulation by virus of host molecular function&apos;</deletedAxiom>
<newAxiom>&apos;suppression by virus of host tetherin activity&apos; SubClassOf &apos;mitigation of host defenses by virus&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039588</classIRI>
<classLabel>suppression by virus of host antigen processing and presentation</classLabel>
<deletedAxiom>&apos;suppression by virus of host antigen processing and presentation&apos; SubClassOf &apos;negative regulation of antigen processing and presentation&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host antigen processing and presentation&apos; EquivalentTo &apos;modulation by virus of host cellular process&apos; and (&apos;negatively regulates&apos; some &apos;antigen processing and presentation&apos;)</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host antigen processing and presentation&apos; SubClassOf &apos;regulation of immune response&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host antigen processing and presentation&apos; SubClassOf &apos;mitigation of host immune response by virus&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host antigen processing and presentation&apos; SubClassOf &apos;modulation by virus of host immune response&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host antigen processing and presentation&apos; SubClassOf &apos;regulation of cellular process&apos;</deletedAxiom>
<newAxiom>&apos;suppression by virus of host antigen processing and presentation&apos; SubClassOf &apos;suppression by virus of host adaptive immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039504</classIRI>
<classLabel>suppression by virus of host adaptive immune response</classLabel>
<deletedAxiom>&apos;suppression by virus of host adaptive immune response&apos; SubClassOf &apos;regulation of cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host adaptive immune response&apos; SubClassOf &apos;negative regulation of adaptive immune response&apos;</deletedAxiom>
<newAxiom>&apos;suppression by virus of host adaptive immune response&apos; SubClassOf &apos;negatively regulates&apos; some &apos;adaptive immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039505</classIRI>
<classLabel>suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II</classLabel>
<newAxiom>&apos;suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II&apos; SubClassOf &apos;negative regulation of adaptive immune response&apos;</newAxiom>
<newAxiom>&apos;suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II&apos; SubClassOf &apos;regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039523</classIRI>
<classLabel>suppression by virus of host RNA polymerase II activity</classLabel>
<deletedAxiom>&apos;suppression by virus of host RNA polymerase II activity&apos; SubClassOf &apos;suppression by virus of host molecular function&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904815</classIRI>
<classLabel>negative regulation of protein localization to chromosome, telomeric region</classLabel>
<newAxiom>&apos;negative regulation of protein localization to chromosome, telomeric region&apos; SubClassOf &apos;negative regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904816</classIRI>
<classLabel>positive regulation of protein localization to chromosome, telomeric region</classLabel>
<newAxiom>&apos;positive regulation of protein localization to chromosome, telomeric region&apos; SubClassOf &apos;positive regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904814</classIRI>
<classLabel>regulation of protein localization to chromosome, telomeric region</classLabel>
<deletedAxiom>&apos;regulation of protein localization to chromosome, telomeric region&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of protein localization to chromosome, telomeric region&apos; SubClassOf &apos;regulation of cellular localization&apos;</newAxiom>
<newAxiom>&apos;regulation of protein localization to chromosome, telomeric region&apos; SubClassOf &apos;regulation of protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904779</classIRI>
<classLabel>regulation of protein localization to centrosome</classLabel>
<deletedAxiom>&apos;regulation of protein localization to centrosome&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of protein localization to centrosome&apos; SubClassOf &apos;regulation of cellular localization&apos;</newAxiom>
<newAxiom>&apos;regulation of protein localization to centrosome&apos; SubClassOf &apos;regulation of protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904781</classIRI>
<classLabel>positive regulation of protein localization to centrosome</classLabel>
<newAxiom>&apos;positive regulation of protein localization to centrosome&apos; SubClassOf &apos;positive regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904780</classIRI>
<classLabel>negative regulation of protein localization to centrosome</classLabel>
<newAxiom>&apos;negative regulation of protein localization to centrosome&apos; SubClassOf &apos;negative regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904786</classIRI>
<classLabel>negative regulation of asymmetric protein localization involved in cell fate determination</classLabel>
<deletedAxiom>&apos;negative regulation of asymmetric protein localization involved in cell fate determination&apos; SubClassOf &apos;negative regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of asymmetric protein localization involved in cell fate determination&apos; SubClassOf &apos;negative regulation of cellular protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904787</classIRI>
<classLabel>positive regulation of asymmetric protein localization involved in cell fate determination</classLabel>
<deletedAxiom>&apos;positive regulation of asymmetric protein localization involved in cell fate determination&apos; SubClassOf &apos;positive regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of asymmetric protein localization involved in cell fate determination&apos; SubClassOf &apos;positive regulation of cellular protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904917</classIRI>
<classLabel>L-arginine transmembrane transport from lysosomal lumen to cytosol</classLabel>
<deletedAxiom>&apos;L-arginine transmembrane transport from lysosomal lumen to cytosol&apos; SubClassOf &apos;L-arginine transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;L-arginine transmembrane transport from lysosomal lumen to cytosol&apos; SubClassOf &apos;L-amino acid transport&apos;</newAxiom>
<newAxiom>&apos;L-arginine transmembrane transport from lysosomal lumen to cytosol&apos; SubClassOf &apos;transports or maintains localization of&apos; some &apos;L-argininium(1+)&apos;</newAxiom>
<newAxiom>&apos;L-arginine transmembrane transport from lysosomal lumen to cytosol&apos; SubClassOf &apos;L-alpha-amino acid transmembrane transport&apos;</newAxiom>
<newAxiom>&apos;L-arginine transmembrane transport from lysosomal lumen to cytosol&apos; SubClassOf &apos;cation transmembrane transport&apos;</newAxiom>
<newAxiom>&apos;L-arginine transmembrane transport from lysosomal lumen to cytosol&apos; SubClassOf &apos;anion transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904950</classIRI>
<classLabel>negative regulation of establishment of protein localization</classLabel>
<deletedAxiom>&apos;negative regulation of establishment of protein localization&apos; SubClassOf &apos;negative regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of establishment of protein localization&apos; SubClassOf &apos;negative regulation of cellular protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904951</classIRI>
<classLabel>positive regulation of establishment of protein localization</classLabel>
<deletedAxiom>&apos;positive regulation of establishment of protein localization&apos; SubClassOf &apos;positive regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of establishment of protein localization&apos; SubClassOf &apos;positive regulation of cellular protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005162</classIRI>
<classLabel>multi cell part structure</classLabel>
<deletedAxiom>&apos;multi cell part structure&apos; SubClassOf &apos;has_component&apos; min 2 &apos;obsolete cell part&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015181</classIRI>
<classLabel>arginine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;arginine transmembrane transporter activity&apos; SubClassOf &apos;basic amino acid transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;arginine transmembrane transporter activity&apos; SubClassOf &apos;organic anion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;arginine transmembrane transporter activity&apos; SubClassOf &apos;transports or maintains localization of&apos; some &apos;argininium(1+)&apos;</deletedAxiom>
<deletedAxiom>&apos;arginine transmembrane transporter activity&apos; SubClassOf &apos;part of&apos; some &apos;arginine transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;arginine transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;arginine transmembrane transporter activity&apos; EquivalentTo &apos;transmembrane transporter activity&apos; and (&apos;transports or maintains localization of&apos; some &apos;argininium(1+)&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002354</classIRI>
<classLabel>yolk sac hematopoietic stem cell</classLabel>
<deletedAxiom>&apos;yolk sac hematopoietic stem cell&apos; SubClassOf &apos;epithelial cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0040029</classIRI>
<classLabel>regulation of gene expression, epigenetic</classLabel>
<newAxiom>&apos;regulation of gene expression, epigenetic&apos; SubClassOf &apos;part of&apos; some &apos;chromatin organization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030414</classIRI>
<classLabel>peptidase inhibitor activity</classLabel>
<newAxiom>&apos;peptidase inhibitor activity&apos; SubClassOf &apos;enzyme inhibitor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900150</classIRI>
<classLabel>regulation of defense response to fungus</classLabel>
<deletedAxiom>&apos;regulation of defense response to fungus&apos; SubClassOf &apos;regulation of immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900180</classIRI>
<classLabel>regulation of protein localization to nucleus</classLabel>
<deletedAxiom>&apos;regulation of protein localization to nucleus&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of protein localization to nucleus&apos; SubClassOf &apos;regulation of cellular localization&apos;</newAxiom>
<newAxiom>&apos;regulation of protein localization to nucleus&apos; SubClassOf &apos;regulation of protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900181</classIRI>
<classLabel>negative regulation of protein localization to nucleus</classLabel>
<newAxiom>&apos;negative regulation of protein localization to nucleus&apos; SubClassOf &apos;negative regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900182</classIRI>
<classLabel>positive regulation of protein localization to nucleus</classLabel>
<newAxiom>&apos;positive regulation of protein localization to nucleus&apos; SubClassOf &apos;positive regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030337</classIRI>
<classLabel>DNA polymerase processivity factor activity</classLabel>
<deletedAxiom>&apos;DNA polymerase processivity factor activity&apos; SubClassOf &apos;enzyme regulator activity&apos;</deletedAxiom>
<newAxiom>&apos;DNA polymerase processivity factor activity&apos; SubClassOf &apos;enzyme activator activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900366</classIRI>
<classLabel>negative regulation of defense response to insect</classLabel>
<deletedAxiom>&apos;negative regulation of defense response to insect&apos; SubClassOf &apos;negative regulation of immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900367</classIRI>
<classLabel>positive regulation of defense response to insect</classLabel>
<deletedAxiom>&apos;positive regulation of defense response to insect&apos; SubClassOf &apos;positive regulation of immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019907</classIRI>
<classLabel>cyclin-dependent protein kinase activating kinase holoenzyme complex</classLabel>
<newAxiom>&apos;cyclin-dependent protein kinase activating kinase holoenzyme complex&apos; SubClassOf &apos;enzyme activator complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005289</classIRI>
<classLabel>high-affinity arginine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;high-affinity arginine transmembrane transporter activity&apos; SubClassOf &apos;arginine transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;high-affinity arginine transmembrane transporter activity&apos; SubClassOf &apos;L-arginine transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;high-affinity arginine transmembrane transporter activity&apos; EquivalentTo &apos;high-affinity basic amino acid transmembrane transporter activity&apos; and (&apos;transports or maintains localization of&apos; some &apos;L-argininium(1+)&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900424</classIRI>
<classLabel>regulation of defense response to bacterium</classLabel>
<deletedAxiom>&apos;regulation of defense response to bacterium&apos; SubClassOf &apos;regulation of immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900425</classIRI>
<classLabel>negative regulation of defense response to bacterium</classLabel>
<deletedAxiom>&apos;negative regulation of defense response to bacterium&apos; SubClassOf &apos;negative regulation of immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900426</classIRI>
<classLabel>positive regulation of defense response to bacterium</classLabel>
<deletedAxiom>&apos;positive regulation of defense response to bacterium&apos; SubClassOf &apos;positive regulation of immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044790</classIRI>
<classLabel>negative regulation by host of viral release from host cell</classLabel>
<deletedAxiom>&apos;negative regulation by host of viral release from host cell&apos; EquivalentTo &apos;negative regulation by host of viral process&apos; and (&apos;negatively regulates&apos; some &apos;viral release from host cell&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation by host of viral release from host cell&apos; SubClassOf &apos;modulation by host of viral release from host cell&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation by host of viral release from host cell&apos; SubClassOf &apos;negative regulation by host of viral process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation by host of viral release from host cell&apos; SubClassOf &apos;negative regulation of viral release from host cell&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation by host of viral release from host cell&apos; SubClassOf &apos;defense response to virus&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044791</classIRI>
<classLabel>positive regulation by host of viral release from host cell</classLabel>
<deletedAxiom>&apos;positive regulation by host of viral release from host cell&apos; EquivalentTo &apos;positive regulation by host of viral process&apos; and (&apos;positively regulates&apos; some &apos;viral release from host cell&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation by host of viral release from host cell&apos; SubClassOf &apos;modulation by host of viral release from host cell&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by host of viral release from host cell&apos; SubClassOf &apos;positive regulation of viral release from host cell&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by host of viral release from host cell&apos; SubClassOf &apos;positive regulation by host of viral process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044796</classIRI>
<classLabel>DNA polymerase processivity factor complex</classLabel>
<deletedAxiom>&apos;DNA polymerase processivity factor complex&apos; SubClassOf &apos;protein-containing complex&apos;</deletedAxiom>
<newAxiom>&apos;DNA polymerase processivity factor complex&apos; SubClassOf &apos;enzyme activator complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044789</classIRI>
<classLabel>modulation by host of viral release from host cell</classLabel>
<deletedAxiom>&apos;modulation by host of viral release from host cell&apos; SubClassOf &apos;modulation by host of viral process&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by host of viral release from host cell&apos; EquivalentTo &apos;modulation by host of viral process&apos; and (&apos;regulates&apos; some &apos;viral release from host cell&apos;)</deletedAxiom>
<deletedAxiom>&apos;modulation by host of viral release from host cell&apos; SubClassOf &apos;regulation of viral release from host cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005085</classIRI>
<classLabel>guanyl-nucleotide exchange factor activity</classLabel>
<deletedAxiom>&apos;guanyl-nucleotide exchange factor activity&apos; SubClassOf &apos;GTPase activator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;guanyl-nucleotide exchange factor activity&apos; EquivalentTo &apos;GTPase activator activity&apos; and (&apos;negatively regulates&apos; some &apos;GDP binding&apos;) and (&apos;positively regulates&apos; some &apos;GTP binding&apos;)</deletedAxiom>
<newAxiom>&apos;guanyl-nucleotide exchange factor activity&apos; SubClassOf &apos;GTPase regulator activity&apos;</newAxiom>
<newAxiom>&apos;guanyl-nucleotide exchange factor activity&apos; EquivalentTo &apos;GTPase regulator activity&apos; and (&apos;negatively regulates&apos; some &apos;GDP binding&apos;) and (&apos;positively regulates&apos; some &apos;GTP binding&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005095</classIRI>
<classLabel>GTPase inhibitor activity</classLabel>
<newAxiom>&apos;GTPase inhibitor activity&apos; SubClassOf &apos;enzyme inhibitor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005096</classIRI>
<classLabel>GTPase activator activity</classLabel>
<newAxiom>&apos;GTPase activator activity&apos; SubClassOf &apos;enzyme activator activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044410</classIRI>
<classLabel>entry into host through natural portals</classLabel>
<deletedAxiom>&apos;entry into host through natural portals&apos; SubClassOf &apos;entry into host&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900831</classIRI>
<classLabel>D-leucine metabolic process</classLabel>
<deletedAxiom>&apos;D-leucine metabolic process&apos; SubClassOf &apos;branched-chain amino acid metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900832</classIRI>
<classLabel>D-leucine catabolic process</classLabel>
<deletedAxiom>&apos;D-leucine catabolic process&apos; SubClassOf &apos;branched-chain amino acid catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900833</classIRI>
<classLabel>D-leucine biosynthetic process</classLabel>
<deletedAxiom>&apos;D-leucine biosynthetic process&apos; SubClassOf &apos;branched-chain amino acid biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044382</classIRI>
<classLabel>CLRC complex localization to heterochromatin</classLabel>
<deletedAxiom>&apos;CLRC complex localization to heterochromatin&apos; SubClassOf &apos;cellular protein-containing complex localization&apos;</deletedAxiom>
<newAxiom>&apos;CLRC complex localization to heterochromatin&apos; SubClassOf &apos;protein-containing complex localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010963</classIRI>
<classLabel>regulation of L-arginine import</classLabel>
<deletedAxiom>&apos;regulation of L-arginine import&apos; SubClassOf &apos;regulates&apos; some &apos;L-arginine transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of L-arginine import&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;L-arginine transport&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of L-arginine import&apos; SubClassOf &apos;regulation of amino acid transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of L-arginine import&apos; SubClassOf &apos;regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140080</classIRI>
<classLabel>class III/IV DNA-(apurinic or apyrimidinic site) endonuclease activity</classLabel>
<deletedAxiom>&apos;class III/IV DNA-(apurinic or apyrimidinic site) endonuclease activity&apos; SubClassOf &apos;endodeoxyribonuclease activity, producing 3&apos;-phosphomonoesters&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140027</classIRI>
<classLabel>establishment of contractile vacuole localization</classLabel>
<deletedAxiom>&apos;establishment of contractile vacuole localization&apos; SubClassOf &apos;establishment of organelle localization&apos;</deletedAxiom>
<newAxiom>&apos;establishment of contractile vacuole localization&apos; SubClassOf &apos;vesicle localization&apos;</newAxiom>
<newAxiom>&apos;establishment of contractile vacuole localization&apos; EquivalentTo &apos;localization&apos; and (&apos;transports or maintains localization of&apos; some &apos;contractile vacuole&apos;)</newAxiom>
<newAxiom>&apos;establishment of contractile vacuole localization&apos; SubClassOf &apos;maintenance of vacuolar location&apos;</newAxiom>
<newAxiom>&apos;establishment of contractile vacuole localization&apos; SubClassOf &apos;transports or maintains localization of&apos; some &apos;contractile vacuole&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046811</classIRI>
<classLabel>histone deacetylase inhibitor activity</classLabel>
<newAxiom>&apos;histone deacetylase inhibitor activity&apos; SubClassOf &apos;enzyme inhibitor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046776</classIRI>
<classLabel>suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I</classLabel>
<deletedAxiom>&apos;suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I&apos; SubClassOf &apos;negative regulation of antigen processing and presentation of peptide antigen via MHC class I&apos;</deletedAxiom>
<newAxiom>&apos;suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I&apos; SubClassOf &apos;negatively regulates&apos; some &apos;antigen processing and presentation of peptide antigen via MHC class I&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032020</classIRI>
<classLabel>ISG15-protein conjugation</classLabel>
<deletedAxiom>&apos;ISG15-protein conjugation&apos; SubClassOf &apos;cellular protein modification process&apos;</deletedAxiom>
<newAxiom>&apos;ISG15-protein conjugation&apos; SubClassOf &apos;protein modification by small protein conjugation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032045</classIRI>
<classLabel>guanyl-nucleotide exchange factor complex</classLabel>
<deletedAxiom>&apos;guanyl-nucleotide exchange factor complex&apos; SubClassOf &apos;GTPase activator complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0014283</classIRI>
<classLabel>piriform cortex layer 3</classLabel>
<deletedAxiom>&apos;piriform cortex layer 3&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061906</classIRI>
<classLabel>autophagosome localization</classLabel>
<deletedAxiom>&apos;autophagosome localization&apos; SubClassOf &apos;organelle localization&apos;</deletedAxiom>
<newAxiom>&apos;autophagosome localization&apos; SubClassOf &apos;maintenance of vacuolar location&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000018</classIRI>
<classLabel>compound eye</classLabel>
<newAxiom>&apos;compound eye&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000023</classIRI>
<classLabel>wing</classLabel>
<deletedAxiom>&apos;wing&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002322 some http://purl.obolibrary.org/obo/ENVO_00000568</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000007</classIRI>
<classLabel>pituitary gland</classLabel>
<deletedAxiom>&apos;pituitary gland&apos; SubClassOf &apos;structure with developmental contribution from neural crest&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061765</classIRI>
<classLabel>modulation by virus of host NIK/NF-kappaB signaling</classLabel>
<deletedAxiom>&apos;modulation by virus of host NIK/NF-kappaB signaling&apos; SubClassOf &apos;regulation of NIK/NF-kappaB signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by virus of host NIK/NF-kappaB signaling&apos; SubClassOf &apos;modulation by virus of host cellular process&apos;</deletedAxiom>
<newAxiom>&apos;modulation by virus of host NIK/NF-kappaB signaling&apos; SubClassOf &apos;modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061459</classIRI>
<classLabel>L-arginine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;L-arginine transmembrane transporter activity&apos; SubClassOf &apos;part of&apos; some &apos;L-arginine transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;L-arginine transmembrane transporter activity&apos; SubClassOf &apos;arginine transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;L-arginine transmembrane transporter activity&apos; SubClassOf &apos;organic anion transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;L-arginine transmembrane transporter activity&apos; SubClassOf &apos;basic amino acid transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;L-arginine transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;L-arginine transmembrane transporter activity&apos; SubClassOf &apos;part of&apos; some &apos;arginine transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036487</classIRI>
<classLabel>nitric-oxide synthase inhibitor activity</classLabel>
<newAxiom>&apos;nitric-oxide synthase inhibitor activity&apos; SubClassOf &apos;enzyme inhibitor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120187</classIRI>
<classLabel>positive regulation of protein localization to chromatin</classLabel>
<newAxiom>&apos;positive regulation of protein localization to chromatin&apos; SubClassOf &apos;positive regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120186</classIRI>
<classLabel>negative regulation of protein localization to chromatin</classLabel>
<newAxiom>&apos;negative regulation of protein localization to chromatin&apos; SubClassOf &apos;negative regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0198738</classIRI>
<classLabel>cell-cell signaling by wnt</classLabel>
<newAxiom>&apos;cell-cell signaling by wnt&apos; SubClassOf &apos;in taxon&apos; only &apos;Metazoa&apos;</newAxiom>
<newAxiom>&apos;cell-cell signaling by wnt&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Metazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051839</classIRI>
<classLabel>regulation by host of cytolysis of symbiont cells</classLabel>
<deletedAxiom>&apos;regulation by host of cytolysis of symbiont cells&apos; SubClassOf &apos;regulation of immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904053</classIRI>
<classLabel>positive regulation of protein targeting to vacuole involved in autophagy</classLabel>
<deletedAxiom>&apos;positive regulation of protein targeting to vacuole involved in autophagy&apos; SubClassOf &apos;positive regulation of cellular protein localization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_6000154</classIRI>
<classLabel>embryonic segment</classLabel>
<deletedAxiom>&apos;embryonic segment&apos; EquivalentTo &apos;organismal segment&apos; and (&apos;part of&apos; some &apos;embryo&apos;)</deletedAxiom>
<newAxiom>&apos;embryonic segment&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Insecta&apos;</newAxiom>
<newAxiom>&apos;embryonic segment&apos; EquivalentTo &apos;organismal segment&apos; and (&apos;part of&apos; some &apos;embryo&apos;) and (&apos;only_in_taxon&apos; some &apos;Insecta&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_6000157</classIRI>
<classLabel>embryonic head segment</classLabel>
<deletedAxiom>&apos;embryonic head segment&apos; EquivalentTo &apos;organismal segment&apos; and (&apos;part of&apos; some &apos;embryonic head&apos;)</deletedAxiom>
<newAxiom>&apos;embryonic head segment&apos; EquivalentTo &apos;organismal segment&apos; and (&apos;part of&apos; some &apos;embryonic head&apos;) and (&apos;only_in_taxon&apos; some &apos;Insecta&apos;)</newAxiom>
<newAxiom>&apos;embryonic head segment&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Insecta&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051664</classIRI>
<classLabel>nuclear pore localization</classLabel>
<deletedAxiom>&apos;nuclear pore localization&apos; SubClassOf &apos;cellular protein-containing complex localization&apos;</deletedAxiom>
<deletedAxiom>&apos;nuclear pore localization&apos; SubClassOf &apos;protein localization to membrane&apos;</deletedAxiom>
<newAxiom>&apos;nuclear pore localization&apos; SubClassOf &apos;protein-containing complex localization&apos;</newAxiom>
<newAxiom>&apos;nuclear pore localization&apos; SubClassOf &apos;localization within membrane&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051601</classIRI>
<classLabel>exocyst localization</classLabel>
<deletedAxiom>&apos;exocyst localization&apos; SubClassOf &apos;cellular protein-containing complex localization&apos;</deletedAxiom>
<newAxiom>&apos;exocyst localization&apos; SubClassOf &apos;protein-containing complex localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000964</classIRI>
<classLabel>cornea</classLabel>
<deletedAxiom>&apos;cornea&apos; SubClassOf &apos;surface structure&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904216</classIRI>
<classLabel>positive regulation of protein import into chloroplast stroma</classLabel>
<deletedAxiom>&apos;positive regulation of protein import into chloroplast stroma&apos; SubClassOf &apos;positive regulation of cellular protein localization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000970</classIRI>
<classLabel>eye</classLabel>
<deletedAxiom>&apos;eye&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904375</classIRI>
<classLabel>regulation of protein localization to cell periphery</classLabel>
<deletedAxiom>&apos;regulation of protein localization to cell periphery&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of protein localization to cell periphery&apos; SubClassOf &apos;regulation of cellular localization&apos;</newAxiom>
<newAxiom>&apos;regulation of protein localization to cell periphery&apos; SubClassOf &apos;regulation of protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904377</classIRI>
<classLabel>positive regulation of protein localization to cell periphery</classLabel>
<newAxiom>&apos;positive regulation of protein localization to cell periphery&apos; SubClassOf &apos;positive regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904376</classIRI>
<classLabel>negative regulation of protein localization to cell periphery</classLabel>
<newAxiom>&apos;negative regulation of protein localization to cell periphery&apos; SubClassOf &apos;negative regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110133</classIRI>
<classLabel>negative regulation of CRISPR-cas system</classLabel>
<deletedAxiom>&apos;negative regulation of CRISPR-cas system&apos; SubClassOf &apos;negative regulation of immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110132</classIRI>
<classLabel>regulation of CRISPR-cas system</classLabel>
<deletedAxiom>&apos;regulation of CRISPR-cas system&apos; SubClassOf &apos;regulation of immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110087</classIRI>
<classLabel>suppression by virus of host protease activator activity</classLabel>
<deletedAxiom>&apos;suppression by virus of host protease activator activity&apos; SubClassOf &apos;suppression by virus of host molecular function&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903400</classIRI>
<classLabel>L-arginine transmembrane transport</classLabel>
<deletedAxiom>&apos;L-arginine transmembrane transport&apos; EquivalentTo &apos;transport&apos; and (&apos;transports or maintains localization of&apos; some &apos;L-argininium(1+)&apos;) and (&apos;results in transport across&apos; some &apos;membrane&apos;)</deletedAxiom>
<deletedAxiom>&apos;L-arginine transmembrane transport&apos; SubClassOf &apos;arginine transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;L-arginine transmembrane transport&apos; SubClassOf &apos;L-alpha-amino acid transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;L-arginine transmembrane transport&apos; SubClassOf &apos;L-arginine transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051127</classIRI>
<classLabel>positive regulation of actin nucleation</classLabel>
<deletedAxiom>&apos;positive regulation of actin nucleation&apos; SubClassOf &apos;positive regulation of actin filament polymerization&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of actin nucleation&apos; SubClassOf &apos;positive regulation of cytoskeleton organization&apos;</newAxiom>
<newAxiom>&apos;positive regulation of actin nucleation&apos; SubClassOf &apos;positive regulation of supramolecular fiber organization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051125</classIRI>
<classLabel>regulation of actin nucleation</classLabel>
<deletedAxiom>&apos;regulation of actin nucleation&apos; SubClassOf &apos;regulation of actin filament polymerization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of actin nucleation&apos; SubClassOf &apos;regulation of actin filament organization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090625</classIRI>
<classLabel>mRNA cleavage involved in gene silencing by siRNA</classLabel>
<deletedAxiom>&apos;mRNA cleavage involved in gene silencing by siRNA&apos; SubClassOf &apos;mRNA cleavage involved in gene silencing&apos;</deletedAxiom>
<newAxiom>&apos;mRNA cleavage involved in gene silencing by siRNA&apos; SubClassOf &apos;mRNA cleavage&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_1000123</classIRI>
<classLabel>metanephric nephron tubule epithelial cell</classLabel>
<newAxiom>&apos;metanephric nephron tubule epithelial cell&apos; SubClassOf &apos;epithelial cell of nephron&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903565</classIRI>
<classLabel>negative regulation of protein localization to cilium</classLabel>
<newAxiom>&apos;negative regulation of protein localization to cilium&apos; SubClassOf &apos;negative regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903564</classIRI>
<classLabel>regulation of protein localization to cilium</classLabel>
<deletedAxiom>&apos;regulation of protein localization to cilium&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of protein localization to cilium&apos; SubClassOf &apos;regulation of protein localization&apos;</newAxiom>
<newAxiom>&apos;regulation of protein localization to cilium&apos; SubClassOf &apos;regulation of cellular localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903566</classIRI>
<classLabel>positive regulation of protein localization to cilium</classLabel>
<newAxiom>&apos;positive regulation of protein localization to cilium&apos; SubClassOf &apos;positive regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090518</classIRI>
<classLabel>L-arginine transmembrane import into vacuole</classLabel>
<deletedAxiom>&apos;L-arginine transmembrane import into vacuole&apos; SubClassOf &apos;L-arginine transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;L-arginine transmembrane import into vacuole&apos; SubClassOf &apos;arginine transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_1000022</classIRI>
<classLabel>mesonephric nephron tubule epithelial cell</classLabel>
<newAxiom>&apos;mesonephric nephron tubule epithelial cell&apos; SubClassOf &apos;epithelial cell of nephron&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_1000090</classIRI>
<classLabel>pronephric nephron tubule epithelial cell</classLabel>
<newAxiom>&apos;pronephric nephron tubule epithelial cell&apos; SubClassOf &apos;epithelial cell of nephron&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016504</classIRI>
<classLabel>peptidase activator activity</classLabel>
<newAxiom>&apos;peptidase activator activity&apos; SubClassOf &apos;enzyme activator activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903747</classIRI>
<classLabel>regulation of establishment of protein localization to mitochondrion</classLabel>
<deletedAxiom>&apos;regulation of establishment of protein localization to mitochondrion&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of establishment of protein localization to mitochondrion&apos; SubClassOf &apos;regulation of cellular localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903749</classIRI>
<classLabel>positive regulation of establishment of protein localization to mitochondrion</classLabel>
<deletedAxiom>&apos;positive regulation of establishment of protein localization to mitochondrion&apos; SubClassOf &apos;positive regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of establishment of protein localization to mitochondrion&apos; SubClassOf &apos;positive regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903748</classIRI>
<classLabel>negative regulation of establishment of protein localization to mitochondrion</classLabel>
<deletedAxiom>&apos;negative regulation of establishment of protein localization to mitochondrion&apos; SubClassOf &apos;negative regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of establishment of protein localization to mitochondrion&apos; SubClassOf &apos;negative regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016441</classIRI>
<classLabel>posttranscriptional gene silencing</classLabel>
<deletedAxiom>&apos;posttranscriptional gene silencing&apos; SubClassOf &apos;gene silencing&apos;</deletedAxiom>
<newAxiom>&apos;posttranscriptional gene silencing&apos; SubClassOf &apos;negative regulation of gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016458</classIRI>
<classLabel>gene silencing</classLabel>
<deletedAxiom>&apos;gene silencing&apos; SubClassOf &apos;negative regulation of gene expression&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903801</classIRI>
<classLabel>L-leucine import across plasma membrane</classLabel>
<deletedAxiom>&apos;L-leucine import across plasma membrane&apos; SubClassOf &apos;leucine transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903826</classIRI>
<classLabel>arginine transmembrane transport</classLabel>
<deletedAxiom>&apos;arginine transmembrane transport&apos; SubClassOf &apos;arginine transport&apos;</deletedAxiom>
<deletedAxiom>&apos;arginine transmembrane transport&apos; EquivalentTo &apos;basic amino acid transport&apos; and (&apos;transports or maintains localization of&apos; some &apos;argininium(1+)&apos;) and (&apos;results in transport across&apos; some &apos;membrane&apos;)</deletedAxiom>
<newAxiom>&apos;arginine transmembrane transport&apos; SubClassOf &apos;transports or maintains localization of&apos; some &apos;L-argininium(1+)&apos;</newAxiom>
<newAxiom>&apos;arginine transmembrane transport&apos; SubClassOf &apos;L-alpha-amino acid transmembrane transport&apos;</newAxiom>
<newAxiom>&apos;arginine transmembrane transport&apos; SubClassOf &apos;L-amino acid transport&apos;</newAxiom>
<newAxiom>&apos;arginine transmembrane transport&apos; EquivalentTo &apos;basic amino acid transport&apos; and (&apos;transports or maintains localization of&apos; some &apos;L-argininium(1+)&apos;) and (&apos;results in transport across&apos; some &apos;membrane&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903828</classIRI>
<classLabel>negative regulation of cellular protein localization</classLabel>
<deletedAxiom>&apos;negative regulation of cellular protein localization&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular protein localization&apos; SubClassOf &apos;negative regulation of cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular protein localization&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;cellular protein localization&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular protein localization&apos; SubClassOf &apos;negatively regulates&apos; some &apos;cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of cellular protein localization&apos; SubClassOf &apos;negative regulation of biological process&apos;</newAxiom>
<newAxiom>&apos;negative regulation of cellular protein localization&apos; SubClassOf &apos;negatively regulates&apos; some &apos;protein localization&apos;</newAxiom>
<newAxiom>&apos;negative regulation of cellular protein localization&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;protein localization&apos;)</newAxiom>
<newAxiom>&apos;negative regulation of cellular protein localization&apos; SubClassOf &apos;regulation of protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903827</classIRI>
<classLabel>regulation of cellular protein localization</classLabel>
<deletedAxiom>&apos;regulation of cellular protein localization&apos; SubClassOf &apos;regulation of protein localization&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular protein localization&apos; SubClassOf &apos;regulation of cellular localization&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular protein localization&apos; SubClassOf &apos;regulates&apos; some &apos;cellular protein localization&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular protein localization&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;cellular protein localization&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903829</classIRI>
<classLabel>positive regulation of cellular protein localization</classLabel>
<deletedAxiom>&apos;positive regulation of cellular protein localization&apos; SubClassOf &apos;positive regulation of cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular protein localization&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular protein localization&apos; SubClassOf &apos;positively regulates&apos; some &apos;cellular protein localization&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular protein localization&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;cellular protein localization&apos;)</deletedAxiom>
<newAxiom>&apos;positive regulation of cellular protein localization&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;protein localization&apos;)</newAxiom>
<newAxiom>&apos;positive regulation of cellular protein localization&apos; SubClassOf &apos;regulation of protein localization&apos;</newAxiom>
<newAxiom>&apos;positive regulation of cellular protein localization&apos; SubClassOf &apos;positively regulates&apos; some &apos;protein localization&apos;</newAxiom>
<newAxiom>&apos;positive regulation of cellular protein localization&apos; SubClassOf &apos;positive regulation of biological process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903785</classIRI>
<classLabel>L-valine transmembrane transport</classLabel>
<deletedAxiom>&apos;L-valine transmembrane transport&apos; SubClassOf &apos;branched-chain amino acid transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090317</classIRI>
<classLabel>negative regulation of intracellular protein transport</classLabel>
<deletedAxiom>&apos;negative regulation of intracellular protein transport&apos; SubClassOf &apos;negative regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of intracellular protein transport&apos; SubClassOf &apos;negatively regulates&apos; some &apos;cellular protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016055</classIRI>
<classLabel>Wnt signaling pathway</classLabel>
<deletedAxiom>&apos;Wnt signaling pathway&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Metazoa&apos;</deletedAxiom>
<deletedAxiom>&apos;Wnt signaling pathway&apos; SubClassOf &apos;in taxon&apos; only &apos;Metazoa&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031507</classIRI>
<classLabel>heterochromatin assembly</classLabel>
<deletedAxiom>&apos;heterochromatin assembly&apos; SubClassOf &apos;gene silencing&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006551</classIRI>
<classLabel>leucine metabolic process</classLabel>
<deletedAxiom>&apos;leucine metabolic process&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has primary input or output&apos; some &apos;leucinate&apos;)</deletedAxiom>
<deletedAxiom>&apos;leucine metabolic process&apos; SubClassOf &apos;cellular amino acid metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;leucine metabolic process&apos; SubClassOf &apos;has primary input or output&apos; some &apos;leucinate&apos;</deletedAxiom>
<newAxiom>&apos;leucine metabolic process&apos; SubClassOf &apos;branched-chain amino acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;leucine metabolic process&apos; SubClassOf &apos;has primary input or output&apos; some &apos;leucine&apos;</newAxiom>
<newAxiom>&apos;leucine metabolic process&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;leucine metabolic process&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has primary input or output&apos; some &apos;leucine&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006552</classIRI>
<classLabel>leucine catabolic process</classLabel>
<deletedAxiom>&apos;leucine catabolic process&apos; SubClassOf &apos;has primary input&apos; some &apos;leucinate&apos;</deletedAxiom>
<deletedAxiom>&apos;leucine catabolic process&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary input&apos; some &apos;leucinate&apos;)</deletedAxiom>
<deletedAxiom>&apos;leucine catabolic process&apos; SubClassOf &apos;cellular amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;leucine catabolic process&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary input&apos; some &apos;leucine&apos;)</newAxiom>
<newAxiom>&apos;leucine catabolic process&apos; SubClassOf &apos;branched-chain amino acid catabolic process&apos;</newAxiom>
<newAxiom>&apos;leucine catabolic process&apos; SubClassOf &apos;has primary input&apos; some &apos;leucine&apos;</newAxiom>
<newAxiom>&apos;leucine catabolic process&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006573</classIRI>
<classLabel>valine metabolic process</classLabel>
<deletedAxiom>&apos;valine metabolic process&apos; SubClassOf &apos;has primary input or output&apos; some &apos;valinate&apos;</deletedAxiom>
<deletedAxiom>&apos;valine metabolic process&apos; SubClassOf &apos;cellular amino acid metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;valine metabolic process&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has primary input or output&apos; some &apos;valinate&apos;)</deletedAxiom>
<newAxiom>&apos;valine metabolic process&apos; SubClassOf &apos;has primary input or output&apos; some &apos;valine&apos;</newAxiom>
<newAxiom>&apos;valine metabolic process&apos; SubClassOf &apos;branched-chain amino acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;valine metabolic process&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has primary input or output&apos; some &apos;valine&apos;)</newAxiom>
<newAxiom>&apos;valine metabolic process&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006574</classIRI>
<classLabel>valine catabolic process</classLabel>
<deletedAxiom>&apos;valine catabolic process&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary input&apos; some &apos;valinate&apos;)</deletedAxiom>
<deletedAxiom>&apos;valine catabolic process&apos; SubClassOf &apos;has primary input&apos; some &apos;valinate&apos;</deletedAxiom>
<deletedAxiom>&apos;valine catabolic process&apos; SubClassOf &apos;cellular amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;valine catabolic process&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary input&apos; some &apos;valine&apos;)</newAxiom>
<newAxiom>&apos;valine catabolic process&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</newAxiom>
<newAxiom>&apos;valine catabolic process&apos; SubClassOf &apos;has primary input&apos; some &apos;valine&apos;</newAxiom>
<newAxiom>&apos;valine catabolic process&apos; SubClassOf &apos;branched-chain amino acid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031445</classIRI>
<classLabel>regulation of heterochromatin assembly</classLabel>
<deletedAxiom>&apos;regulation of heterochromatin assembly&apos; SubClassOf &apos;regulation of gene silencing&apos;</deletedAxiom>
<newAxiom>&apos;regulation of heterochromatin assembly&apos; SubClassOf &apos;regulation of gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031452</classIRI>
<classLabel>negative regulation of heterochromatin assembly</classLabel>
<deletedAxiom>&apos;negative regulation of heterochromatin assembly&apos; SubClassOf &apos;negative regulation of gene silencing&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of heterochromatin assembly&apos; SubClassOf &apos;positive regulation of gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070961</classIRI>
<classLabel>positive regulation of neutrophil mediated killing of symbiont cell</classLabel>
<deletedAxiom>&apos;positive regulation of neutrophil mediated killing of symbiont cell&apos; SubClassOf &apos;positive regulation of immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004679</classIRI>
<classLabel>dentate gyrus molecular layer</classLabel>
<deletedAxiom>&apos;dentate gyrus molecular layer&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002473 some &apos;obsolete cell part&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006335</classIRI>
<classLabel>DNA replication-dependent nucleosome assembly</classLabel>
<deletedAxiom>&apos;DNA replication-dependent nucleosome assembly&apos; SubClassOf &apos;nucleosome assembly&apos;</deletedAxiom>
<newAxiom>&apos;DNA replication-dependent nucleosome assembly&apos; SubClassOf &apos;chromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006336</classIRI>
<classLabel>DNA replication-independent nucleosome assembly</classLabel>
<deletedAxiom>&apos;DNA replication-independent nucleosome assembly&apos; SubClassOf &apos;nucleosome assembly&apos;</deletedAxiom>
<newAxiom>&apos;DNA replication-independent nucleosome assembly&apos; SubClassOf &apos;chromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070955</classIRI>
<classLabel>negative regulation of neutrophil mediated killing of symbiont cell</classLabel>
<deletedAxiom>&apos;negative regulation of neutrophil mediated killing of symbiont cell&apos; SubClassOf &apos;negative regulation of immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070949</classIRI>
<classLabel>regulation of neutrophil mediated killing of symbiont cell</classLabel>
<deletedAxiom>&apos;regulation of neutrophil mediated killing of symbiont cell&apos; SubClassOf &apos;regulation of immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045815</classIRI>
<classLabel>positive regulation of gene expression, epigenetic</classLabel>
<newAxiom>&apos;positive regulation of gene expression, epigenetic&apos; EquivalentTo &apos;regulation of gene expression, epigenetic&apos; and (&apos;positively regulates&apos; some &apos;gene expression&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031234</classIRI>
<classLabel>extrinsic component of cytoplasmic side of plasma membrane</classLabel>
<deletedAxiom>&apos;extrinsic component of cytoplasmic side of plasma membrane&apos; SubClassOf &apos;part of&apos; some &apos;intracellular anatomical structure&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070817</classIRI>
<classLabel>P-TEFb-cap methyltransferase complex localization</classLabel>
<deletedAxiom>&apos;P-TEFb-cap methyltransferase complex localization&apos; SubClassOf &apos;cellular protein-containing complex localization&apos;</deletedAxiom>
<newAxiom>&apos;P-TEFb-cap methyltransferase complex localization&apos; SubClassOf &apos;protein-containing complex localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031144</classIRI>
<classLabel>proteasome localization</classLabel>
<deletedAxiom>&apos;proteasome localization&apos; SubClassOf &apos;cellular protein-containing complex localization&apos;</deletedAxiom>
<newAxiom>&apos;proteasome localization&apos; SubClassOf &apos;protein-containing complex localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070728</classIRI>
<classLabel>leucine binding</classLabel>
<deletedAxiom>&apos;leucine binding&apos; SubClassOf &apos;carboxylic acid binding&apos;</deletedAxiom>
<deletedAxiom>&apos;leucine binding&apos; SubClassOf &apos;has input&apos; some &apos;leucinate&apos;</deletedAxiom>
<deletedAxiom>&apos;leucine binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;leucinate&apos;)</deletedAxiom>
<newAxiom>&apos;leucine binding&apos; SubClassOf &apos;amino acid binding&apos;</newAxiom>
<newAxiom>&apos;leucine binding&apos; SubClassOf &apos;has input&apos; some &apos;leucine&apos;</newAxiom>
<newAxiom>&apos;leucine binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;leucine&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070634</classIRI>
<classLabel>transepithelial ammonium transport</classLabel>
<deletedAxiom>&apos;transepithelial ammonium transport&apos; SubClassOf &apos;ammonium transport&apos;</deletedAxiom>
<newAxiom>&apos;transepithelial ammonium transport&apos; SubClassOf &apos;cation transport&apos;</newAxiom>
<newAxiom>&apos;transepithelial ammonium transport&apos; SubClassOf &apos;transports or maintains localization of&apos; some &apos;ammonium&apos;</newAxiom>
<newAxiom>&apos;transepithelial ammonium transport&apos; SubClassOf &apos;nitrogen compound transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031047</classIRI>
<classLabel>gene silencing by RNA</classLabel>
<deletedAxiom>&apos;gene silencing by RNA&apos; SubClassOf &apos;process has causal agent&apos; some &apos;ribonucleic acid&apos;</deletedAxiom>
<deletedAxiom>&apos;gene silencing by RNA&apos; EquivalentTo &apos;gene silencing&apos; and (&apos;process has causal agent&apos; some &apos;ribonucleic acid&apos;)</deletedAxiom>
<deletedAxiom>&apos;gene silencing by RNA&apos; SubClassOf &apos;gene silencing&apos;</deletedAxiom>
<newAxiom>&apos;gene silencing by RNA&apos; SubClassOf &apos;negative regulation of gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033566</classIRI>
<classLabel>gamma-tubulin complex localization</classLabel>
<deletedAxiom>&apos;gamma-tubulin complex localization&apos; SubClassOf &apos;cellular protein-containing complex localization&apos;</deletedAxiom>
<newAxiom>&apos;gamma-tubulin complex localization&apos; SubClassOf &apos;protein-containing complex localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033503</classIRI>
<classLabel>HULC complex</classLabel>
<deletedAxiom>&apos;HULC complex&apos; SubClassOf &apos;ubiquitin ligase complex&apos;</deletedAxiom>
<deletedAxiom>&apos;HULC complex&apos; SubClassOf &apos;part of&apos; some &apos;heterochromatin&apos;</deletedAxiom>
<newAxiom>&apos;HULC complex&apos; SubClassOf &apos;part of&apos; some &apos;chromatin&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047987</classIRI>
<classLabel>hydroperoxide dehydratase activity</classLabel>
<deletedAxiom>&apos;hydroperoxide dehydratase activity&apos; SubClassOf &apos;hydro-lyase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033157</classIRI>
<classLabel>regulation of intracellular protein transport</classLabel>
<deletedAxiom>&apos;regulation of intracellular protein transport&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of intracellular protein transport&apos; SubClassOf &apos;regulates&apos; some &apos;cellular protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072765</classIRI>
<classLabel>centromere localization</classLabel>
<deletedAxiom>&apos;centromere localization&apos; SubClassOf &apos;cellular protein-containing complex localization&apos;</deletedAxiom>
<newAxiom>&apos;centromere localization&apos; SubClassOf &apos;protein-containing complex localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072742</classIRI>
<classLabel>SAGA complex localization to transcription regulatory region</classLabel>
<deletedAxiom>&apos;SAGA complex localization to transcription regulatory region&apos; SubClassOf &apos;cellular protein-containing complex localization&apos;</deletedAxiom>
<newAxiom>&apos;SAGA complex localization to transcription regulatory region&apos; SubClassOf &apos;protein-containing complex localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008047</classIRI>
<classLabel>enzyme activator activity</classLabel>
<deletedAxiom>&apos;enzyme activator activity&apos; EquivalentTo &apos;molecular function activator activity&apos; and (&apos;positively regulates&apos; some &apos;catalytic activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;enzyme activator activity&apos; SubClassOf &apos;molecular function activator activity&apos;</deletedAxiom>
<newAxiom>&apos;enzyme activator activity&apos; EquivalentTo &apos;molecular function regulator&apos; and (&apos;positively regulates&apos; some &apos;catalytic activity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072688</classIRI>
<classLabel>SHREC complex localization</classLabel>
<deletedAxiom>&apos;SHREC complex localization&apos; SubClassOf &apos;cellular protein-containing complex localization&apos;</deletedAxiom>
<newAxiom>&apos;SHREC complex localization&apos; SubClassOf &apos;protein-containing complex localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072488</classIRI>
<classLabel>ammonium transmembrane transport</classLabel>
<deletedAxiom>&apos;ammonium transmembrane transport&apos; SubClassOf &apos;ammonium transport&apos;</deletedAxiom>
<newAxiom>&apos;ammonium transmembrane transport&apos; SubClassOf &apos;transports or maintains localization of&apos; some &apos;ammonium&apos;</newAxiom>
<newAxiom>&apos;ammonium transmembrane transport&apos; SubClassOf &apos;nitrogen compound transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072356</classIRI>
<classLabel>chromosome passenger complex localization to kinetochore</classLabel>
<deletedAxiom>&apos;chromosome passenger complex localization to kinetochore&apos; SubClassOf &apos;cellular protein-containing complex localization&apos;</deletedAxiom>
<newAxiom>&apos;chromosome passenger complex localization to kinetochore&apos; SubClassOf &apos;protein-containing complex localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_1000549</classIRI>
<classLabel>kidney cortex collecting duct epithelial cell</classLabel>
<deletedAxiom>&apos;kidney cortex collecting duct epithelial cell&apos; SubClassOf &apos;renal cortical epithelial cell&apos;</deletedAxiom>
<newAxiom>&apos;kidney cortex collecting duct epithelial cell&apos; SubClassOf &apos;kidney cortical cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_1000615</classIRI>
<classLabel>kidney cortex tubule cell</classLabel>
<newAxiom>&apos;kidney cortex tubule cell&apos; SubClassOf &apos;epithelial cell of nephron&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_1000494</classIRI>
<classLabel>nephron tubule epithelial cell</classLabel>
<newAxiom>&apos;nephron tubule epithelial cell&apos; SubClassOf &apos;epithelial cell of nephron&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_1000507</classIRI>
<classLabel>kidney tubule cell</classLabel>
<deletedAxiom>&apos;kidney tubule cell&apos; SubClassOf &apos;epithelial cell of nephron&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000350</classIRI>
<classLabel>amnioserosal cell</classLabel>
<deletedAxiom>&apos;amnioserosal cell&apos; SubClassOf &apos;epithelial cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003906</classIRI>
<classLabel>DNA-(apurinic or apyrimidinic site) endonuclease activity</classLabel>
<deletedAxiom>&apos;DNA-(apurinic or apyrimidinic site) endonuclease activity&apos; SubClassOf &apos;endonuclease activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000598</classIRI>
<classLabel>pyramidal neuron</classLabel>
<deletedAxiom>&apos;pyramidal neuron&apos; EquivalentTo &apos;CNS neuron (sensu Vertebrata)&apos; and (&apos;bearer of&apos; some http://purl.obolibrary.org/obo/PATO_0070015)</deletedAxiom>
<newAxiom>&apos;pyramidal neuron&apos; EquivalentTo &apos;neuron&apos; and (&apos;bearer of&apos; some http://purl.obolibrary.org/obo/PATO_0070015)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062240</classIRI>
<classLabel>euchromatin-nuclear membrane anchor activity</classLabel>
<deletedAxiom>&apos;euchromatin-nuclear membrane anchor activity&apos; SubClassOf &apos;protein-membrane adaptor activity&apos;</deletedAxiom>
<newAxiom>&apos;euchromatin-nuclear membrane anchor activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140707</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062239</classIRI>
<classLabel>heterochromatin-nuclear membrane anchor activity</classLabel>
<deletedAxiom>&apos;heterochromatin-nuclear membrane anchor activity&apos; SubClassOf &apos;protein-membrane adaptor activity&apos;</deletedAxiom>
<newAxiom>&apos;heterochromatin-nuclear membrane anchor activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140707</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0009025</classIRI>
<classLabel>mesothelial cell of large intestine</classLabel>
<deletedAxiom>&apos;mesothelial cell of large intestine&apos; EquivalentTo &apos;mesothelial cell&apos; and (&apos;part of&apos; some &apos;large intestine&apos;)</deletedAxiom>
<deletedAxiom>&apos;mesothelial cell of large intestine&apos; SubClassOf &apos;epithelial cell of large intestine&apos;</deletedAxiom>
<newAxiom>&apos;mesothelial cell of large intestine&apos; EquivalentTo &apos;mesothelial cell&apos; and (&apos;part of&apos; some &apos;colon&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903066</classIRI>
<classLabel>regulation of protein localization to cell tip</classLabel>
<deletedAxiom>&apos;regulation of protein localization to cell tip&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of protein localization to cell tip&apos; SubClassOf &apos;regulation of protein localization&apos;</newAxiom>
<newAxiom>&apos;regulation of protein localization to cell tip&apos; SubClassOf &apos;regulation of cellular localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903068</classIRI>
<classLabel>positive regulation of protein localization to cell tip</classLabel>
<newAxiom>&apos;positive regulation of protein localization to cell tip&apos; SubClassOf &apos;positive regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903067</classIRI>
<classLabel>negative regulation of protein localization to cell tip</classLabel>
<newAxiom>&apos;negative regulation of protein localization to cell tip&apos; SubClassOf &apos;negative regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990429</classIRI>
<classLabel>peroxisomal importomer complex</classLabel>
<deletedAxiom>&apos;peroxisomal importomer complex&apos; SubClassOf &apos;Pex17p-Pex14p docking complex&apos;</deletedAxiom>
<newAxiom>&apos;peroxisomal importomer complex&apos; SubClassOf &apos;capable of part of&apos; some &apos;protein import into peroxisome matrix&apos;</newAxiom>
<newAxiom>&apos;peroxisomal importomer complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;capable of part of&apos; some &apos;protein import into peroxisome matrix&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990415</classIRI>
<classLabel>Pex17p-Pex14p docking complex</classLabel>
<deletedAxiom>&apos;Pex17p-Pex14p docking complex&apos; SubClassOf &apos;capable of part of&apos; some &apos;protein import into peroxisome matrix&apos;</deletedAxiom>
<deletedAxiom>&apos;Pex17p-Pex14p docking complex&apos; SubClassOf &apos;protein-containing complex&apos;</deletedAxiom>
<deletedAxiom>&apos;Pex17p-Pex14p docking complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;capable of part of&apos; some &apos;protein import into peroxisome matrix&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990453</classIRI>
<classLabel>nucleosome disassembly/reassembly complex</classLabel>
<deletedAxiom>&apos;nucleosome disassembly/reassembly complex&apos; SubClassOf &apos;capable of part of&apos; some &apos;DNA replication-dependent nucleosome disassembly&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990571</classIRI>
<classLabel>meiotic centromere clustering</classLabel>
<deletedAxiom>&apos;meiotic centromere clustering&apos; SubClassOf &apos;establishment of protein localization to organelle&apos;</deletedAxiom>
<deletedAxiom>&apos;meiotic centromere clustering&apos; SubClassOf &apos;protein localization to microtubule cytoskeleton&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0000066</classIRI>
<classLabel>epithelial cell</classLabel>
<deletedAxiom>&apos;epithelial cell&apos; EquivalentTo &apos;animal cell&apos; and (&apos;part of&apos; some &apos;epithelium&apos;)</deletedAxiom>
<newAxiom>&apos;epithelial cell&apos; SubClassOf &apos;part of&apos; some &apos;epithelium&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_1001225</classIRI>
<classLabel>kidney collecting duct cell</classLabel>
<deletedAxiom>&apos;kidney collecting duct cell&apos; SubClassOf &apos;epithelial cell of nephron&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902023</classIRI>
<classLabel>L-arginine transport</classLabel>
<deletedAxiom>&apos;L-arginine transport&apos; EquivalentTo &apos;transport&apos; and (&apos;transports or maintains localization of&apos; some &apos;L-argininium(1+)&apos;)</deletedAxiom>
<deletedAxiom>&apos;L-arginine transport&apos; SubClassOf &apos;transports or maintains localization of&apos; some &apos;L-argininium(1+)&apos;</deletedAxiom>
<deletedAxiom>&apos;L-arginine transport&apos; SubClassOf &apos;L-amino acid transport&apos;</deletedAxiom>
<deletedAxiom>&apos;L-arginine transport&apos; SubClassOf &apos;arginine transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902079</classIRI>
<classLabel>D-valine catabolic process</classLabel>
<deletedAxiom>&apos;D-valine catabolic process&apos; SubClassOf &apos;branched-chain amino acid catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990735</classIRI>
<classLabel>gamma-tubulin complex localization to mitotic spindle pole body</classLabel>
<deletedAxiom>&apos;gamma-tubulin complex localization to mitotic spindle pole body&apos; SubClassOf &apos;protein localization to mitotic spindle pole body&apos;</deletedAxiom>
<newAxiom>&apos;gamma-tubulin complex localization to mitotic spindle pole body&apos; SubClassOf &apos;has target end location&apos; some &apos;mitotic spindle pole body&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902114</classIRI>
<classLabel>D-valine metabolic process</classLabel>
<deletedAxiom>&apos;D-valine metabolic process&apos; SubClassOf &apos;branched-chain amino acid metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_6001730</classIRI>
<classLabel>insect larval head</classLabel>
<deletedAxiom>&apos;insect larval head&apos; EquivalentTo &apos;head&apos; and (&apos;part of&apos; some &apos;larva&apos;)</deletedAxiom>
<newAxiom>&apos;insect larval head&apos; EquivalentTo &apos;head&apos; and (&apos;part of&apos; some &apos;larva&apos;) and (&apos;only_in_taxon&apos; some &apos;Insecta&apos;)</newAxiom>
<newAxiom>&apos;insect larval head&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Insecta&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902186</classIRI>
<classLabel>regulation of viral release from host cell</classLabel>
<deletedAxiom>&apos;regulation of viral release from host cell&apos; SubClassOf &apos;regulation of viral life cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of viral release from host cell&apos; SubClassOf &apos;regulation of biological process involved in symbiotic interaction&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of viral release from host cell&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;viral release from host cell&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of viral release from host cell&apos; SubClassOf &apos;regulates&apos; some &apos;viral release from host cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_6001732</classIRI>
<classLabel>insect larval head segment</classLabel>
<deletedAxiom>&apos;insect larval head segment&apos; SubClassOf &apos;insect larval segment&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902188</classIRI>
<classLabel>positive regulation of viral release from host cell</classLabel>
<deletedAxiom>&apos;positive regulation of viral release from host cell&apos; SubClassOf &apos;positive regulation of viral life cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of viral release from host cell&apos; SubClassOf &apos;positively regulates&apos; some &apos;viral release from host cell&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of viral release from host cell&apos; SubClassOf &apos;regulation of viral release from host cell&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of viral release from host cell&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;viral release from host cell&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902187</classIRI>
<classLabel>negative regulation of viral release from host cell</classLabel>
<deletedAxiom>&apos;negative regulation of viral release from host cell&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;viral release from host cell&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of viral release from host cell&apos; SubClassOf &apos;negatively regulates&apos; some &apos;viral release from host cell&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of viral release from host cell&apos; SubClassOf &apos;negative regulation of viral process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of viral release from host cell&apos; SubClassOf &apos;regulation of viral release from host cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052373</classIRI>
<classLabel>suppression of symbiont entry into host by host</classLabel>
<deletedAxiom>&apos;suppression of symbiont entry into host by host&apos; SubClassOf &apos;defense response to other organism&apos;</deletedAxiom>
<newAxiom>&apos;suppression of symbiont entry into host by host&apos; SubClassOf &apos;defense response to symbiont&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_6001729</classIRI>
<classLabel>insect larval segment</classLabel>
<deletedAxiom>&apos;insect larval segment&apos; EquivalentTo &apos;organismal segment&apos; and (&apos;part of&apos; some &apos;larva&apos;)</deletedAxiom>
<newAxiom>&apos;insect larval segment&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Insecta&apos;</newAxiom>
<newAxiom>&apos;insect larval segment&apos; EquivalentTo &apos;organismal segment&apos; and (&apos;part of&apos; some &apos;larva&apos;) and (&apos;only_in_taxon&apos; some &apos;Insecta&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990818</classIRI>
<classLabel>L-arginine transmembrane export from vacuole</classLabel>
<deletedAxiom>&apos;L-arginine transmembrane export from vacuole&apos; SubClassOf &apos;L-arginine transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;L-arginine transmembrane export from vacuole&apos; SubClassOf &apos;anion transmembrane transport&apos;</newAxiom>
<newAxiom>&apos;L-arginine transmembrane export from vacuole&apos; SubClassOf &apos;cation transmembrane transport&apos;</newAxiom>
<newAxiom>&apos;L-arginine transmembrane export from vacuole&apos; SubClassOf &apos;L-amino acid transport&apos;</newAxiom>
<newAxiom>&apos;L-arginine transmembrane export from vacuole&apos; SubClassOf &apos;L-alpha-amino acid transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902289</classIRI>
<classLabel>negative regulation of defense response to oomycetes</classLabel>
<deletedAxiom>&apos;negative regulation of defense response to oomycetes&apos; SubClassOf &apos;negative regulation of immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902288</classIRI>
<classLabel>regulation of defense response to oomycetes</classLabel>
<deletedAxiom>&apos;regulation of defense response to oomycetes&apos; SubClassOf &apos;regulation of immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990849</classIRI>
<classLabel>maintenance of vacuolar location</classLabel>
<deletedAxiom>&apos;maintenance of vacuolar location&apos; EquivalentTo &apos;maintenance of location in cell&apos; and (&apos;transports or maintains localization of&apos; some &apos;vacuole&apos;)</deletedAxiom>
<deletedAxiom>&apos;maintenance of vacuolar location&apos; SubClassOf &apos;maintenance of organelle location&apos;</deletedAxiom>
<newAxiom>&apos;maintenance of vacuolar location&apos; EquivalentTo &apos;localization&apos; and (&apos;transports or maintains localization of&apos; some &apos;vacuole&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902290</classIRI>
<classLabel>positive regulation of defense response to oomycetes</classLabel>
<deletedAxiom>&apos;positive regulation of defense response to oomycetes&apos; SubClassOf &apos;positive regulation of immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902364</classIRI>
<classLabel>negative regulation of protein localization to spindle pole body</classLabel>
<newAxiom>&apos;negative regulation of protein localization to spindle pole body&apos; SubClassOf &apos;negative regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902363</classIRI>
<classLabel>regulation of protein localization to spindle pole body</classLabel>
<deletedAxiom>&apos;regulation of protein localization to spindle pole body&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of protein localization to spindle pole body&apos; SubClassOf &apos;regulation of cellular localization&apos;</newAxiom>
<newAxiom>&apos;regulation of protein localization to spindle pole body&apos; SubClassOf &apos;regulation of protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902365</classIRI>
<classLabel>positive regulation of protein localization to spindle pole body</classLabel>
<newAxiom>&apos;positive regulation of protein localization to spindle pole body&apos; SubClassOf &apos;positive regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042769</classIRI>
<classLabel>DNA damage response, detection of DNA damage</classLabel>
<deletedAxiom>&apos;DNA damage response, detection of DNA damage&apos; SubClassOf &apos;cellular response to DNA damage stimulus&apos;</deletedAxiom>
<deletedAxiom>&apos;DNA damage response, detection of DNA damage&apos; SubClassOf &apos;detection of stimulus&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990920</classIRI>
<classLabel>proteasome localization to nuclear periphery</classLabel>
<deletedAxiom>&apos;proteasome localization to nuclear periphery&apos; SubClassOf &apos;protein localization to nuclear periphery&apos;</deletedAxiom>
<newAxiom>&apos;proteasome localization to nuclear periphery&apos; SubClassOf &apos;has target end location&apos; some &apos;nuclear periphery&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902474</classIRI>
<classLabel>positive regulation of protein localization to synapse</classLabel>
<deletedAxiom>&apos;positive regulation of protein localization to synapse&apos; SubClassOf &apos;positive regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of protein localization to synapse&apos; SubClassOf &apos;positive regulation of cellular protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052067</classIRI>
<classLabel>antiphagocytosis</classLabel>
<deletedAxiom>&apos;antiphagocytosis&apos; SubClassOf &apos;modulation by symbiont of entry into host&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052034</classIRI>
<classLabel>effector-mediated suppression of host pattern-triggered immunity</classLabel>
<deletedAxiom>&apos;effector-mediated suppression of host pattern-triggered immunity&apos; SubClassOf &apos;suppression by symbiont of host innate immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902773</classIRI>
<classLabel>GTPase activator complex</classLabel>
<deletedAxiom>&apos;GTPase activator complex&apos; SubClassOf &apos;protein-containing complex&apos;</deletedAxiom>
<newAxiom>&apos;GTPase activator complex&apos; SubClassOf &apos;enzyme activator complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902697</classIRI>
<classLabel>valine catabolic process to isobutanol</classLabel>
<deletedAxiom>&apos;valine catabolic process to isobutanol&apos; SubClassOf &apos;branched-chain amino acid catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;valine catabolic process to isobutanol&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;valine catabolic process to isobutanol&apos; SubClassOf &apos;has primary input&apos; some &apos;valine&apos;</deletedAxiom>
<newAxiom>&apos;valine catabolic process to isobutanol&apos; SubClassOf &apos;valine catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902816</classIRI>
<classLabel>regulation of protein localization to microtubule</classLabel>
<deletedAxiom>&apos;regulation of protein localization to microtubule&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of protein localization to microtubule&apos; SubClassOf &apos;regulation of protein localization&apos;</newAxiom>
<newAxiom>&apos;regulation of protein localization to microtubule&apos; SubClassOf &apos;regulation of cellular localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902817</classIRI>
<classLabel>negative regulation of protein localization to microtubule</classLabel>
<newAxiom>&apos;negative regulation of protein localization to microtubule&apos; SubClassOf &apos;negative regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150119</classIRI>
<classLabel>negative regulation of protein localization to cell-cell junction</classLabel>
<deletedAxiom>&apos;negative regulation of protein localization to cell-cell junction&apos; SubClassOf &apos;negative regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of protein localization to cell-cell junction&apos; SubClassOf &apos;negative regulation of cellular protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150107</classIRI>
<classLabel>positive regulation of protein localization to cell-cell junction</classLabel>
<deletedAxiom>&apos;positive regulation of protein localization to cell-cell junction&apos; SubClassOf &apos;positive regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of protein localization to cell-cell junction&apos; SubClassOf &apos;positive regulation of cellular protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140706</classIRI>
<classLabel>protein-containing complex localization to centriolar satellite</classLabel>
<deletedAxiom>&apos;protein-containing complex localization to centriolar satellite&apos; SubClassOf &apos;cellular protein-containing complex localization&apos;</deletedAxiom>
<newAxiom>&apos;protein-containing complex localization to centriolar satellite&apos; SubClassOf &apos;protein-containing complex localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150032</classIRI>
<classLabel>positive regulation of protein localization to lysosome</classLabel>
<newAxiom>&apos;positive regulation of protein localization to lysosome&apos; SubClassOf &apos;positive regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150031</classIRI>
<classLabel>regulation of protein localization to lysosome</classLabel>
<deletedAxiom>&apos;regulation of protein localization to lysosome&apos; SubClassOf &apos;regulation of cellular protein localization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of protein localization to lysosome&apos; SubClassOf &apos;regulation of protein localization&apos;</newAxiom>
<newAxiom>&apos;regulation of protein localization to lysosome&apos; SubClassOf &apos;regulation of cellular localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150033</classIRI>
<classLabel>negative regulation of protein localization to lysosome</classLabel>
<newAxiom>&apos;negative regulation of protein localization to lysosome&apos; SubClassOf &apos;negative regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140673</classIRI>
<classLabel>co-transcriptional chromatin reassembly</classLabel>
<deletedAxiom>&apos;co-transcriptional chromatin reassembly&apos; SubClassOf &apos;part of&apos; some &apos;transcription by RNA polymerase II&apos;</deletedAxiom>
<newAxiom>&apos;co-transcriptional chromatin reassembly&apos; SubClassOf &apos;part of&apos; some &apos;transcription elongation from RNA polymerase II promoter&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140631</classIRI>
<classLabel>aldehyde dehydrogenase (NAD+) inhibitor activity</classLabel>
<deletedAxiom>&apos;aldehyde dehydrogenase (NAD+) inhibitor activity&apos; SubClassOf &apos;enzyme regulator activity&apos;</deletedAxiom>
<newAxiom>&apos;aldehyde dehydrogenase (NAD+) inhibitor activity&apos; SubClassOf &apos;enzyme inhibitor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140620</classIRI>
<classLabel>DNA strand exchange inhibitor activity</classLabel>
<deletedAxiom>&apos;DNA strand exchange inhibitor activity&apos; SubClassOf &apos;enzyme regulator activity&apos;</deletedAxiom>
<newAxiom>&apos;DNA strand exchange inhibitor activity&apos; SubClassOf &apos;enzyme inhibitor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140619</classIRI>
<classLabel>DNA strand exchange activator activity</classLabel>
<deletedAxiom>&apos;DNA strand exchange activator activity&apos; SubClassOf &apos;enzyme regulator activity&apos;</deletedAxiom>
<newAxiom>&apos;DNA strand exchange activator activity&apos; SubClassOf &apos;enzyme activator activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140567</classIRI>
<classLabel>transmembrane protein dislocase activity</classLabel>
<newAxiom>&apos;transmembrane protein dislocase activity&apos; SubClassOf &apos;ATP-dependent activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140403</classIRI>
<classLabel>effector-mediated suppression of host innate immune response</classLabel>
<newAxiom>&apos;effector-mediated suppression of host innate immune response&apos; SubClassOf &apos;suppression by symbiont of host innate immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032418</classIRI>
<classLabel>lysosome localization</classLabel>
<deletedAxiom>&apos;lysosome localization&apos; SubClassOf &apos;organelle localization&apos;</deletedAxiom>
<newAxiom>&apos;lysosome localization&apos; SubClassOf &apos;maintenance of vacuolar location&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003083</classIRI>
<classLabel>trunk neural crest</classLabel>
<deletedAxiom>&apos;trunk neural crest&apos; SubClassOf &apos;structure with developmental contribution from neural crest&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003097</classIRI>
<classLabel>dorsal fin</classLabel>
<deletedAxiom>&apos;dorsal fin&apos; SubClassOf &apos;structure with developmental contribution from neural crest&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046970</classIRI>
<classLabel>NAD-dependent histone deacetylase activity (H4-K16 specific)</classLabel>
<deletedAxiom>&apos;NAD-dependent histone deacetylase activity (H4-K16 specific)&apos; SubClassOf &apos;NAD-dependent histone deacetylase activity&apos;</deletedAxiom>
<newAxiom>&apos;NAD-dependent histone deacetylase activity (H4-K16 specific)&apos; SubClassOf &apos;NAD-dependent histone deacetylase activity (H3-K9 specific)&apos;</newAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/SO_0001243</classIRI>
<classLabel>miRNA_primary_transcript_region</classLabel>
<newAxiom>'miRNA_primary_transcript_region' SubClassOf 'primary_transcript_region'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/SO_0001244</classIRI>
<classLabel>pre_miRNA</classLabel>
<newAxiom>'pre_miRNA' SubClassOf 'miRNA_primary_transcript_region'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0039261</classIRI>
<classLabel>pancreatic artery</classLabel>
<newAxiom>'pancreatic artery' SubClassOf 'part of' some 'splenic artery'</newAxiom>
<newAxiom>'pancreatic artery' SubClassOf 'systemic artery'</newAxiom>
<newAxiom>'pancreatic artery' EquivalentTo 'artery' and (http://purl.obolibrary.org/obo/RO_0002178 some 'pancreas')</newAxiom>
<newAxiom>'pancreatic artery' SubClassOf http://purl.obolibrary.org/obo/RO_0002380 some 'splenic artery'</newAxiom>
<newAxiom>'pancreatic artery' SubClassOf http://purl.obolibrary.org/obo/RO_0002178 some 'pancreas'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0039222</classIRI>
<classLabel>cystic artery</classLabel>
<newAxiom>'cystic artery' SubClassOf 'part of' some 'right hepatic artery'</newAxiom>
<newAxiom>'cystic artery' EquivalentTo 'artery' and (http://purl.obolibrary.org/obo/RO_0002178 some 'cystic duct')</newAxiom>
<newAxiom>'cystic artery' SubClassOf http://purl.obolibrary.org/obo/RO_0002178 some 'cystic duct'</newAxiom>
<newAxiom>'cystic artery' SubClassOf 'artery'</newAxiom>
<newAxiom>'cystic artery' SubClassOf 'liver blood vessel'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0039228</classIRI>
<classLabel>sigmoid vein</classLabel>
<newAxiom>'sigmoid vein' SubClassOf 'vein'</newAxiom>
<newAxiom>'sigmoid vein' EquivalentTo 'vein' and (http://purl.obolibrary.org/obo/RO_0002179 some 'sigmoid colon')</newAxiom>
<newAxiom>'sigmoid vein' SubClassOf http://purl.obolibrary.org/obo/RO_0002179 some 'sigmoid colon'</newAxiom>
<newAxiom>'sigmoid vein' SubClassOf 'part of' some 'inferior mesenteric vein'</newAxiom>
<newAxiom>'sigmoid vein' SubClassOf http://purl.obolibrary.org/obo/RO_0002376 some 'inferior mesenteric vein'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000202</classIRI>
<classLabel>glial blood brain barrier</classLabel>
<newAxiom>'glial blood brain barrier' EquivalentTo 'blood brain barrier' and (http://purl.obolibrary.org/obo/RO_0002473 some 'glial cell')</newAxiom>
<newAxiom>'glial blood brain barrier' SubClassOf 'blood brain barrier'</newAxiom>
<newAxiom>'glial blood brain barrier' SubClassOf http://purl.obolibrary.org/obo/RO_0002473 some 'glial cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160005</classIRI>
<classLabel>PAT complex</classLabel>
<newAxiom>'PAT complex' SubClassOf 'endoplasmic reticulum protein-containing complex'</newAxiom>
<newAxiom>'PAT complex' SubClassOf 'part of' some 'integral component of endoplasmic reticulum membrane'</newAxiom>
<newAxiom>'PAT complex' SubClassOf 'membrane protein complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106400</classIRI>
<classLabel>double-strand break repair via transcription-associated homologous recombination</classLabel>
<newAxiom>'double-strand break repair via transcription-associated homologous recombination' SubClassOf 'double-strand break repair via homologous recombination'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106405</classIRI>
<classLabel>isoprenoid diphosphate phosphatase activity</classLabel>
<newAxiom>'isoprenoid diphosphate phosphatase activity' SubClassOf 'pyrophosphatase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106402</classIRI>
<classLabel>Lewis x epitope biosynthetic process</classLabel>
<newAxiom>'Lewis x epitope biosynthetic process' SubClassOf 'carbohydrate metabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106398</classIRI>
<classLabel>negative regulation of R7 cell fate commitment</classLabel>
<newAxiom>'negative regulation of R7 cell fate commitment' EquivalentTo 'biological regulation' and ('negatively regulates' some 'R7 cell fate commitment')</newAxiom>
<newAxiom>'negative regulation of R7 cell fate commitment' SubClassOf 'negative regulation of cell fate commitment'</newAxiom>
<newAxiom>'negative regulation of R7 cell fate commitment' SubClassOf 'regulation of R7 cell fate commitment'</newAxiom>
<newAxiom>'negative regulation of R7 cell fate commitment' SubClassOf 'negatively regulates' some 'R7 cell fate commitment'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106397</classIRI>
<classLabel>positive regulation of R7 cell fate commitment</classLabel>
<newAxiom>'positive regulation of R7 cell fate commitment' SubClassOf 'positively regulates' some 'R7 cell fate commitment'</newAxiom>
<newAxiom>'positive regulation of R7 cell fate commitment' EquivalentTo 'biological regulation' and ('positively regulates' some 'R7 cell fate commitment')</newAxiom>
<newAxiom>'positive regulation of R7 cell fate commitment' SubClassOf 'positive regulation of cell fate commitment'</newAxiom>
<newAxiom>'positive regulation of R7 cell fate commitment' SubClassOf 'regulation of R7 cell fate commitment'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106399</classIRI>
<classLabel>acyl-coenzyme A diphosphatase activity</classLabel>
<newAxiom>'acyl-coenzyme A diphosphatase activity' SubClassOf 'pyrophosphatase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106394</classIRI>
<classLabel>negative regulation of palmitic acid catabolic process</classLabel>
<newAxiom>'negative regulation of palmitic acid catabolic process' SubClassOf 'negative regulation of cellular catabolic process'</newAxiom>
<newAxiom>'negative regulation of palmitic acid catabolic process' SubClassOf 'negatively regulates' some 'palmitic acid catabolic process'</newAxiom>
<newAxiom>'negative regulation of palmitic acid catabolic process' SubClassOf 'negative regulation of fatty acid metabolic process'</newAxiom>
<newAxiom>'negative regulation of palmitic acid catabolic process' SubClassOf 'negative regulation of lipid catabolic process'</newAxiom>
<newAxiom>'negative regulation of palmitic acid catabolic process' EquivalentTo 'biological regulation' and ('negatively regulates' some 'palmitic acid catabolic process')</newAxiom>
<newAxiom>'negative regulation of palmitic acid catabolic process' SubClassOf 'regulation of palmitic acid catabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106393</classIRI>
<classLabel>regulation of palmitic acid catabolic process</classLabel>
<newAxiom>'regulation of palmitic acid catabolic process' SubClassOf 'regulates' some 'palmitic acid catabolic process'</newAxiom>
<newAxiom>'regulation of palmitic acid catabolic process' SubClassOf 'regulation of cellular catabolic process'</newAxiom>
<newAxiom>'regulation of palmitic acid catabolic process' SubClassOf 'regulation of fatty acid metabolic process'</newAxiom>
<newAxiom>'regulation of palmitic acid catabolic process' EquivalentTo 'biological regulation' and ('regulates' some 'palmitic acid catabolic process')</newAxiom>
<newAxiom>'regulation of palmitic acid catabolic process' SubClassOf 'regulation of lipid catabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106396</classIRI>
<classLabel>regulation of R7 cell fate commitment</classLabel>
<newAxiom>'regulation of R7 cell fate commitment' SubClassOf 'regulates' some 'R7 cell fate commitment'</newAxiom>
<newAxiom>'regulation of R7 cell fate commitment' SubClassOf 'regulation of cell fate commitment'</newAxiom>
<newAxiom>'regulation of R7 cell fate commitment' EquivalentTo 'biological regulation' and ('regulates' some 'R7 cell fate commitment')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106395</classIRI>
<classLabel>positive regulation of palmitic acid catabolic process</classLabel>
<newAxiom>'positive regulation of palmitic acid catabolic process' SubClassOf 'positive regulation of lipid catabolic process'</newAxiom>
<newAxiom>'positive regulation of palmitic acid catabolic process' SubClassOf 'positively regulates' some 'palmitic acid catabolic process'</newAxiom>
<newAxiom>'positive regulation of palmitic acid catabolic process' SubClassOf 'positive regulation of fatty acid metabolic process'</newAxiom>
<newAxiom>'positive regulation of palmitic acid catabolic process' SubClassOf 'positive regulation of cellular catabolic process'</newAxiom>
<newAxiom>'positive regulation of palmitic acid catabolic process' SubClassOf 'regulation of palmitic acid catabolic process'</newAxiom>
<newAxiom>'positive regulation of palmitic acid catabolic process' EquivalentTo 'biological regulation' and ('positively regulates' some 'palmitic acid catabolic process')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106392</classIRI>
<classLabel>bI3 intron splicing complex</classLabel>
<newAxiom>'bI3 intron splicing complex' SubClassOf 'capable of part of' some 'Group I intron splicing'</newAxiom>
<newAxiom>'bI3 intron splicing complex' SubClassOf 'endoribonuclease complex'</newAxiom>
<newAxiom>'bI3 intron splicing complex' SubClassOf 'capable of part of' some 'mRNA processing'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106391</classIRI>
<classLabel>bI4 intron splicing complex</classLabel>
<newAxiom>'bI4 intron splicing complex' SubClassOf 'capable of part of' some 'mRNA processing'</newAxiom>
<newAxiom>'bI4 intron splicing complex' SubClassOf 'endoribonuclease complex'</newAxiom>
<newAxiom>'bI4 intron splicing complex' SubClassOf 'capable of part of' some 'Group I intron splicing'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0009006</classIRI>
<classLabel>enteroendocrine cell of small intestine</classLabel>
<newAxiom>'enteroendocrine cell of small intestine' EquivalentTo 'enteroendocrine cell' and ('part of' some 'small intestine')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0009039</classIRI>
<classLabel>colon goblet cell</classLabel>
<newAxiom>'colon goblet cell' EquivalentTo 'goblet cell' and ('part of' some 'colon')</newAxiom>
<newAxiom>'colon goblet cell' SubClassOf 'large intestine goblet cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0009038</classIRI>
<classLabel>colon macrophage</classLabel>
<newAxiom>'colon macrophage' EquivalentTo 'macrophage' and ('part of' some 'colon')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0009042</classIRI>
<classLabel>enteroendocrine cell of colon</classLabel>
<newAxiom>'enteroendocrine cell of colon' EquivalentTo 'enteroendocrine cell' and ('part of' some 'colon')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140717</classIRI>
<classLabel>entry into host through the stromata</classLabel>
<newAxiom>'entry into host through the stromata' SubClassOf 'entry into host'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140715</classIRI>
<classLabel>serine-tRNA ligase complex</classLabel>
<newAxiom>'serine-tRNA ligase complex' SubClassOf 'catalytic complex'</newAxiom>
<newAxiom>'serine-tRNA ligase complex' SubClassOf 'capable of' some 'serine-tRNA ligase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140710</classIRI>
<classLabel>regulation of Frizzled Nuclear Import pathway</classLabel>
<newAxiom>'regulation of Frizzled Nuclear Import pathway' SubClassOf 'regulates' some 'Frizzled Nuclear Import pathway'</newAxiom>
<newAxiom>'regulation of Frizzled Nuclear Import pathway' EquivalentTo 'biological regulation' and ('regulates' some 'Frizzled Nuclear Import pathway')</newAxiom>
<newAxiom>'regulation of Frizzled Nuclear Import pathway' SubClassOf 'regulation of non-canonical Wnt signaling pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140714</classIRI>
<classLabel>large ribosomal subunit pre-assembly complex</classLabel>
<newAxiom>'large ribosomal subunit pre-assembly complex' SubClassOf 'capable of part of' some 'ribosomal large subunit assembly'</newAxiom>
<newAxiom>'large ribosomal subunit pre-assembly complex' SubClassOf 'chaperone complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140713</classIRI>
<classLabel>histone chaperone activity</classLabel>
<newAxiom>'histone chaperone activity' SubClassOf 'protein carrier chaperone'</newAxiom>
<newAxiom>'histone chaperone activity' SubClassOf 'has_part' some 'histone binding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140712</classIRI>
<classLabel>negative regulation of Frizzled Nuclear Import pathway</classLabel>
<newAxiom>'negative regulation of Frizzled Nuclear Import pathway' SubClassOf 'regulation of Frizzled Nuclear Import pathway'</newAxiom>
<newAxiom>'negative regulation of Frizzled Nuclear Import pathway' SubClassOf 'negatively regulates' some 'Frizzled Nuclear Import pathway'</newAxiom>
<newAxiom>'negative regulation of Frizzled Nuclear Import pathway' SubClassOf 'negative regulation of non-canonical Wnt signaling pathway'</newAxiom>
<newAxiom>'negative regulation of Frizzled Nuclear Import pathway' EquivalentTo 'biological regulation' and ('negatively regulates' some 'Frizzled Nuclear Import pathway')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140711</classIRI>
<classLabel>positive regulation of Frizzled Nuclear Import pathway</classLabel>
<newAxiom>'positive regulation of Frizzled Nuclear Import pathway' SubClassOf 'positively regulates' some 'Frizzled Nuclear Import pathway'</newAxiom>
<newAxiom>'positive regulation of Frizzled Nuclear Import pathway' SubClassOf 'regulation of Frizzled Nuclear Import pathway'</newAxiom>
<newAxiom>'positive regulation of Frizzled Nuclear Import pathway' SubClassOf 'positive regulation of non-canonical Wnt signaling pathway'</newAxiom>
<newAxiom>'positive regulation of Frizzled Nuclear Import pathway' EquivalentTo 'biological regulation' and ('positively regulates' some 'Frizzled Nuclear Import pathway')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140707</classIRI>
<classLabel>chromatin-nuclear membrane anchor activity</classLabel>
<newAxiom>'chromatin-nuclear membrane anchor activity' SubClassOf 'protein-membrane adaptor activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140709</classIRI>
<classLabel>Frizzled Nuclear Import pathway</classLabel>
<newAxiom>'Frizzled Nuclear Import pathway' SubClassOf 'non-canonical Wnt signaling pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140708</classIRI>
<classLabel>CAT tailing</classLabel>
<newAxiom>'CAT tailing' SubClassOf 'part of' some 'ribosome-associated ubiquitin-dependent protein catabolic process'</newAxiom>
<newAxiom>'CAT tailing' SubClassOf 'cytoplasmic translational elongation'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/ENVO_00000568</classIRI>
</deletedClass>
</deletedClasses>
</diffReport>