<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
88
</numberChangedClasses>
<numberNewClasses>
18
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044278</classIRI>
<classLabel>cell wall disruption in another organism</classLabel>
<deletedAxiom>&apos;cell wall disruption in another organism&apos; SubClassOf &apos;modulation of process of another organism&apos;</deletedAxiom>
<newAxiom>&apos;cell wall disruption in another organism&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140975</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019226</classIRI>
<classLabel>transmission of nerve impulse</classLabel>
<deletedAxiom>&apos;transmission of nerve impulse&apos; SubClassOf &apos;multicellular organismal signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019239</classIRI>
<classLabel>deaminase activity</classLabel>
<deletedAxiom>&apos;deaminase activity&apos; SubClassOf &apos;hydrolase activity&apos;</deletedAxiom>
<newAxiom>&apos;deaminase activity&apos; SubClassOf &apos;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009435</classIRI>
<classLabel>NAD biosynthetic process</classLabel>
<newAxiom>&apos;NAD biosynthetic process&apos; SubClassOf &apos;NAD metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048815</classIRI>
<classLabel>hermaphrodite genitalia morphogenesis</classLabel>
<deletedAxiom>&apos;hermaphrodite genitalia morphogenesis&apos; SubClassOf &apos;genitalia morphogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;hermaphrodite genitalia morphogenesis&apos; SubClassOf &apos;part of&apos; some &apos;hermaphrodite genitalia development&apos;</deletedAxiom>
<deletedAxiom>&apos;hermaphrodite genitalia morphogenesis&apos; SubClassOf &apos;results in morphogenesis of&apos; some &apos;hermaphrodite gonad&apos;</deletedAxiom>
<deletedAxiom>&apos;hermaphrodite genitalia morphogenesis&apos; EquivalentTo &apos;anatomical structure morphogenesis&apos; and (&apos;results in morphogenesis of&apos; some &apos;hermaphrodite gonad&apos;)</deletedAxiom>
<deletedAxiom>&apos;hermaphrodite genitalia morphogenesis&apos; SubClassOf &apos;gonad morphogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000712</classIRI>
<classLabel>resolution of meiotic recombination intermediates</classLabel>
<deletedAxiom>&apos;resolution of meiotic recombination intermediates&apos; SubClassOf &apos;part of&apos; some &apos;meiotic chromosome separation&apos;</deletedAxiom>
<newAxiom>&apos;resolution of meiotic recombination intermediates&apos; SubClassOf &apos;part of&apos; some &apos;meiotic chromosome segregation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009009</classIRI>
<classLabel>site-specific recombinase activity</classLabel>
<deletedAxiom>&apos;site-specific recombinase activity&apos; SubClassOf &apos;catalytic activity, acting on DNA&apos;</deletedAxiom>
<newAxiom>&apos;site-specific recombinase activity&apos; SubClassOf &apos;integrase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009037</classIRI>
<classLabel>tyrosine-based site-specific recombinase activity</classLabel>
<deletedAxiom>&apos;tyrosine-based site-specific recombinase activity&apos; SubClassOf &apos;integrase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097494</classIRI>
<classLabel>regulation of vesicle size</classLabel>
<newAxiom>&apos;regulation of vesicle size&apos; SubClassOf &apos;regulates characteristic&apos; some &apos;vesicle size&apos;</newAxiom>
<newAxiom>&apos;regulation of vesicle size&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates characteristic&apos; some &apos;vesicle size&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097167</classIRI>
<classLabel>circadian regulation of translation</classLabel>
<deletedAxiom>&apos;circadian regulation of translation&apos; SubClassOf &apos;multicellular organismal process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990356</classIRI>
<classLabel>sumoylated E2 ligase complex</classLabel>
<deletedAxiom>&apos;sumoylated E2 ligase complex&apos; SubClassOf &apos;catalytic complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004810</classIRI>
<classLabel>tRNA adenylyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA adenylyltransferase activity&apos; SubClassOf &apos;RNA adenylyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;tRNA adenylyltransferase activity&apos; SubClassOf &apos;cytidylyltransferase activity&apos;</newAxiom>
<newAxiom>&apos;tRNA adenylyltransferase activity&apos; SubClassOf &apos;catalytic activity, acting on a tRNA&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004744</classIRI>
<classLabel>retinal isomerase activity</classLabel>
<deletedAxiom>&apos;retinal isomerase activity&apos; SubClassOf &apos;cis-trans isomerase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004153</classIRI>
<classLabel>dihydropterin deaminase activity</classLabel>
<newAxiom>&apos;dihydropterin deaminase activity&apos; SubClassOf &apos;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043784</classIRI>
<classLabel>cob(II)yrinic acid a,c-diamide reductase activity</classLabel>
<deletedAxiom>&apos;cob(II)yrinic acid a,c-diamide reductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on metal ions, flavin as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004013</classIRI>
<classLabel>adenosylhomocysteinase activity</classLabel>
<deletedAxiom>&apos;adenosylhomocysteinase activity&apos; SubClassOf &apos;trialkylsulfonium hydrolase activity&apos;</deletedAxiom>
<newAxiom>&apos;adenosylhomocysteinase activity&apos; SubClassOf &apos;hydrolase activity, acting on carbon-sulfur bonds&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102430</classIRI>
<classLabel>alpha-linolenate delta5 desaturase activity</classLabel>
<deletedAxiom>&apos;alpha-linolenate delta5 desaturase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043494</classIRI>
<classLabel>CLRC complex</classLabel>
<deletedAxiom>&apos;CLRC complex&apos; SubClassOf &apos;Cul4B-RING E3 ubiquitin ligase complex&apos;</deletedAxiom>
<newAxiom>&apos;CLRC complex&apos; SubClassOf &apos;Cul4-RING E3 ubiquitin ligase complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008979</classIRI>
<classLabel>prophage integrase activity</classLabel>
<deletedAxiom>&apos;prophage integrase activity&apos; SubClassOf &apos;integrase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043000</classIRI>
<classLabel>Golgi to plasma membrane CFTR protein transport</classLabel>
<deletedAxiom>&apos;Golgi to plasma membrane CFTR protein transport&apos; SubClassOf &apos;Golgi to plasma membrane protein transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043002</classIRI>
<classLabel>negative regulation of Golgi to plasma membrane CFTR protein transport</classLabel>
<deletedAxiom>&apos;negative regulation of Golgi to plasma membrane CFTR protein transport&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;Golgi to plasma membrane CFTR protein transport&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of Golgi to plasma membrane CFTR protein transport&apos; SubClassOf &apos;regulation of Golgi to plasma membrane CFTR protein transport&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of Golgi to plasma membrane CFTR protein transport&apos; SubClassOf &apos;negatively regulates&apos; some &apos;Golgi to plasma membrane CFTR protein transport&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of Golgi to plasma membrane CFTR protein transport&apos; SubClassOf &apos;negative regulation of Golgi to plasma membrane protein transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043003</classIRI>
<classLabel>positive regulation of Golgi to plasma membrane CFTR protein transport</classLabel>
<deletedAxiom>&apos;positive regulation of Golgi to plasma membrane CFTR protein transport&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;Golgi to plasma membrane CFTR protein transport&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of Golgi to plasma membrane CFTR protein transport&apos; SubClassOf &apos;regulation of Golgi to plasma membrane CFTR protein transport&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of Golgi to plasma membrane CFTR protein transport&apos; SubClassOf &apos;positive regulation of Golgi to plasma membrane protein transport&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of Golgi to plasma membrane CFTR protein transport&apos; SubClassOf &apos;positively regulates&apos; some &apos;Golgi to plasma membrane CFTR protein transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043004</classIRI>
<classLabel>cytoplasmic sequestering of CFTR protein</classLabel>
<deletedAxiom>&apos;cytoplasmic sequestering of CFTR protein&apos; SubClassOf &apos;cytoplasmic sequestering of protein&apos;</deletedAxiom>
<deletedAxiom>&apos;cytoplasmic sequestering of CFTR protein&apos; SubClassOf &apos;negative regulation of Golgi to plasma membrane CFTR protein transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008660</classIRI>
<classLabel>1-aminocyclopropane-1-carboxylate deaminase activity</classLabel>
<deletedAxiom>&apos;1-aminocyclopropane-1-carboxylate deaminase activity&apos; SubClassOf &apos;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045454</classIRI>
<classLabel>cell redox homeostasis</classLabel>
<deletedAxiom>&apos;cell redox homeostasis&apos; SubClassOf &apos;regulation of cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035892</classIRI>
<classLabel>modulation of platelet aggregation in another organism</classLabel>
<deletedAxiom>&apos;modulation of platelet aggregation in another organism&apos; SubClassOf &apos;disruption of cells of another organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060883</classIRI>
<classLabel>regulation of basement membrane disassembly involved in semicircular canal fusion by cell communication</classLabel>
<deletedAxiom>&apos;regulation of basement membrane disassembly involved in semicircular canal fusion by cell communication&apos; SubClassOf &apos;regulates&apos; some &apos;basement membrane disassembly involved in semicircular canal fusion&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of basement membrane disassembly involved in semicircular canal fusion by cell communication&apos; SubClassOf &apos;regulation of embryonic development&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of basement membrane disassembly involved in semicircular canal fusion by cell communication&apos; SubClassOf &apos;regulation of animal organ morphogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of basement membrane disassembly involved in semicircular canal fusion by cell communication&apos; SubClassOf &apos;regulation of basement membrane organization&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of basement membrane disassembly involved in semicircular canal fusion by cell communication&apos; SubClassOf &apos;regulation of extracellular matrix disassembly&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of basement membrane disassembly involved in semicircular canal fusion by cell communication&apos; SubClassOf &apos;cell communication&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035637</classIRI>
<classLabel>multicellular organismal signaling</classLabel>
<deletedAxiom>&apos;multicellular organismal signaling&apos; SubClassOf &apos;signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;multicellular organismal signaling&apos; SubClassOf &apos;multicellular organismal process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060605</classIRI>
<classLabel>tube lumen cavitation</classLabel>
<deletedAxiom>&apos;tube lumen cavitation&apos; SubClassOf &apos;results in formation of&apos; some &apos;tube lumen&apos;</deletedAxiom>
<deletedAxiom>&apos;tube lumen cavitation&apos; EquivalentTo &apos;anatomical structure formation involved in morphogenesis&apos; and (&apos;results in formation of&apos; some &apos;tube lumen&apos;)</deletedAxiom>
<newAxiom>&apos;tube lumen cavitation&apos; SubClassOf &apos;results in changes to anatomical or cellular structure&apos; some &apos;tube lumen&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098933</classIRI>
<classLabel>disruption by symbiont of host cell envelope</classLabel>
<newAxiom>&apos;disruption by symbiont of host cell envelope&apos; SubClassOf &apos;disruption by symbiont of host cellular component&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905012</classIRI>
<classLabel>regulation of &apos;de novo&apos; NAD biosynthetic process from tryptophan</classLabel>
<newAxiom>&apos;regulation of &apos;de novo&apos; NAD biosynthetic process from tryptophan&apos; SubClassOf &apos;regulation of NAD metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905013</classIRI>
<classLabel>negative regulation of &apos;de novo&apos; NAD biosynthetic process from tryptophan</classLabel>
<newAxiom>&apos;negative regulation of &apos;de novo&apos; NAD biosynthetic process from tryptophan&apos; SubClassOf &apos;negative regulation of NAD metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905014</classIRI>
<classLabel>positive regulation of &apos;de novo&apos; NAD biosynthetic process from tryptophan</classLabel>
<newAxiom>&apos;positive regulation of &apos;de novo&apos; NAD biosynthetic process from tryptophan&apos; SubClassOf &apos;positive regulation of NAD metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098619</classIRI>
<classLabel>selenocysteine-tRNA ligase activity</classLabel>
<newAxiom>&apos;selenocysteine-tRNA ligase activity&apos; SubClassOf not (&apos;in taxon&apos; some &apos;Dikarya&apos;)</newAxiom>
<newAxiom>&apos;selenocysteine-tRNA ligase activity&apos; DisjointWith &apos;in taxon&apos; some &apos;Dikarya&apos;</newAxiom>
<newAxiom>&apos;selenocysteine-tRNA ligase activity&apos; SubClassOf &apos;in taxon&apos; some (not (&apos;Dikarya&apos;))</newAxiom>
<newAxiom>&apos;selenocysteine-tRNA ligase activity&apos; SubClassOf &apos;in taxon&apos; some (not (&apos;Embryophyta&apos;))</newAxiom>
<newAxiom>&apos;selenocysteine-tRNA ligase activity&apos; DisjointWith &apos;in taxon&apos; some &apos;Embryophyta&apos;</newAxiom>
<newAxiom>&apos;selenocysteine-tRNA ligase activity&apos; SubClassOf not (&apos;in taxon&apos; some &apos;Embryophyta&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050601</classIRI>
<classLabel>myristoyl-CoA 11-(Z) desaturase activity</classLabel>
<deletedAxiom>&apos;myristoyl-CoA 11-(Z) desaturase activity&apos; SubClassOf &apos;acyl-CoA desaturase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001680</classIRI>
<classLabel>tRNA 3&apos;-terminal CCA addition</classLabel>
<deletedAxiom>&apos;tRNA 3&apos;-terminal CCA addition&apos; SubClassOf &apos;has_part&apos; some &apos;CTP:3&apos;-cytidine-tRNA cytidylyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050540</classIRI>
<classLabel>2-aminomuconate deaminase activity</classLabel>
<deletedAxiom>&apos;2-aminomuconate deaminase activity&apos; SubClassOf &apos;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001514</classIRI>
<classLabel>selenocysteine incorporation</classLabel>
<newAxiom>&apos;selenocysteine incorporation&apos; SubClassOf not (&apos;in taxon&apos; some &apos;Dikarya&apos;)</newAxiom>
<newAxiom>&apos;selenocysteine incorporation&apos; DisjointWith &apos;in taxon&apos; some &apos;Embryophyta&apos;</newAxiom>
<newAxiom>&apos;selenocysteine incorporation&apos; DisjointWith &apos;in taxon&apos; some &apos;Dikarya&apos;</newAxiom>
<newAxiom>&apos;selenocysteine incorporation&apos; SubClassOf not (&apos;in taxon&apos; some &apos;Embryophyta&apos;)</newAxiom>
<newAxiom>&apos;selenocysteine incorporation&apos; SubClassOf &apos;in taxon&apos; some (not (&apos;Dikarya&apos;))</newAxiom>
<newAxiom>&apos;selenocysteine incorporation&apos; SubClassOf &apos;in taxon&apos; some (not (&apos;Embryophyta&apos;))</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039664</classIRI>
<classLabel>lysis of host organelle involved in viral entry into host cell</classLabel>
<deletedAxiom>&apos;lysis of host organelle involved in viral entry into host cell&apos; SubClassOf &apos;has_part&apos; some &apos;disruption by virus of host cell membrane&apos;</deletedAxiom>
<newAxiom>&apos;lysis of host organelle involved in viral entry into host cell&apos; SubClassOf &apos;has_part&apos; some &apos;membrane disruption in another organism&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030895</classIRI>
<classLabel>apolipoprotein B mRNA editing enzyme complex</classLabel>
<deletedAxiom>&apos;apolipoprotein B mRNA editing enzyme complex&apos; SubClassOf &apos;catalytic complex&apos;</deletedAxiom>
<newAxiom>&apos;apolipoprotein B mRNA editing enzyme complex&apos; SubClassOf &apos;mRNA editing complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039012</classIRI>
<classLabel>pronephric sinus development</classLabel>
<deletedAxiom>&apos;pronephric sinus development&apos; SubClassOf &apos;results in development of&apos; some &apos;pronephric sinus&apos;</deletedAxiom>
<deletedAxiom>&apos;pronephric sinus development&apos; EquivalentTo &apos;anatomical structure development&apos; and (&apos;results in development of&apos; some &apos;pronephric sinus&apos;)</deletedAxiom>
<newAxiom>&apos;pronephric sinus development&apos; SubClassOf &apos;results in changes to anatomical or cellular structure&apos; some &apos;pronephric sinus&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0040035</classIRI>
<classLabel>hermaphrodite genitalia development</classLabel>
<deletedAxiom>&apos;hermaphrodite genitalia development&apos; EquivalentTo &apos;anatomical structure development&apos; and (&apos;results in development of&apos; some &apos;hermaphrodite gonad&apos;)</deletedAxiom>
<deletedAxiom>&apos;hermaphrodite genitalia development&apos; SubClassOf &apos;results in development of&apos; some &apos;hermaphrodite gonad&apos;</deletedAxiom>
<deletedAxiom>&apos;hermaphrodite genitalia development&apos; SubClassOf &apos;gonad development&apos;</deletedAxiom>
<deletedAxiom>&apos;hermaphrodite genitalia development&apos; SubClassOf &apos;genitalia development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019674</classIRI>
<classLabel>NAD metabolic process</classLabel>
<deletedAxiom>&apos;NAD metabolic process&apos; SubClassOf &apos;has primary input or output&apos; some &apos;NAD(1-)&apos;</deletedAxiom>
<deletedAxiom>&apos;NAD metabolic process&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has primary input or output&apos; some &apos;NAD(1-)&apos;)</deletedAxiom>
<newAxiom>&apos;NAD metabolic process&apos; SubClassOf &apos;has primary input or output&apos; some &apos;NAD&apos;</newAxiom>
<newAxiom>&apos;NAD metabolic process&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has primary input or output&apos; some &apos;NAD&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019677</classIRI>
<classLabel>NAD catabolic process</classLabel>
<deletedAxiom>&apos;NAD catabolic process&apos; SubClassOf &apos;nicotinamide nucleotide metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;NAD catabolic process&apos; SubClassOf &apos;NAD metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044660</classIRI>
<classLabel>viral release by cytolysis via pore formation in host cell membrane</classLabel>
<newAxiom>&apos;viral release by cytolysis via pore formation in host cell membrane&apos; SubClassOf &apos;has_part&apos; some &apos;membrane disruption in another organism&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044662</classIRI>
<classLabel>disruption by virus of host cell membrane</classLabel>
<deletedAxiom>&apos;disruption by virus of host cell membrane&apos; SubClassOf &apos;membrane disruption in another organism&apos;</deletedAxiom>
<deletedAxiom>&apos;disruption by virus of host cell membrane&apos; SubClassOf &apos;modification by symbiont of host cell membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;disruption by virus of host cell membrane&apos; SubClassOf &apos;modulation by virus of host process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044656</classIRI>
<classLabel>regulation of post-lysosomal vacuole size</classLabel>
<deletedAxiom>&apos;regulation of post-lysosomal vacuole size&apos; SubClassOf &apos;regulation of cellular component size&apos;</deletedAxiom>
<newAxiom>&apos;regulation of post-lysosomal vacuole size&apos; SubClassOf &apos;regulation of vesicle size&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044659</classIRI>
<classLabel>viral release from host cell by cytolysis</classLabel>
<deletedAxiom>&apos;viral release from host cell by cytolysis&apos; SubClassOf &apos;has_part&apos; some &apos;cytolysis by symbiont of host cells&apos;</deletedAxiom>
<newAxiom>&apos;viral release from host cell by cytolysis&apos; SubClassOf &apos;cytolysis by symbiont of host cells&apos;</newAxiom>
<newAxiom>&apos;viral release from host cell by cytolysis&apos; SubClassOf &apos;membrane disruption in another organism&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044364</classIRI>
<classLabel>disruption of cells of another organism</classLabel>
<deletedAxiom>&apos;disruption of cells of another organism&apos; SubClassOf &apos;modulation of process of another organism&apos;</deletedAxiom>
<newAxiom>&apos;disruption of cells of another organism&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140975</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046761</classIRI>
<classLabel>viral budding from plasma membrane</classLabel>
<deletedAxiom>&apos;viral budding from plasma membrane&apos; EquivalentTo &apos;viral budding&apos; and (&apos;has input&apos; some &apos;host cell plasma membrane&apos;)</deletedAxiom>
<deletedAxiom>&apos;viral budding from plasma membrane&apos; SubClassOf &apos;has input&apos; some &apos;host cell plasma membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061686</classIRI>
<classLabel>hercynylcysteine sulfoxide synthase activity</classLabel>
<deletedAxiom>&apos;hercynylcysteine sulfoxide synthase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen&apos;</deletedAxiom>
<newAxiom>&apos;hercynylcysteine sulfoxide synthase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120241</classIRI>
<classLabel>2-iminobutanoate/2-iminopropanoate deaminase</classLabel>
<deletedAxiom>&apos;2-iminobutanoate/2-iminopropanoate deaminase&apos; SubClassOf &apos;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061337</classIRI>
<classLabel>cardiac conduction</classLabel>
<deletedAxiom>&apos;cardiac conduction&apos; SubClassOf &apos;multicellular organismal signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051969</classIRI>
<classLabel>regulation of transmission of nerve impulse</classLabel>
<deletedAxiom>&apos;regulation of transmission of nerve impulse&apos; SubClassOf &apos;regulation of signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051971</classIRI>
<classLabel>positive regulation of transmission of nerve impulse</classLabel>
<deletedAxiom>&apos;positive regulation of transmission of nerve impulse&apos; SubClassOf &apos;positive regulation of signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051970</classIRI>
<classLabel>negative regulation of transmission of nerve impulse</classLabel>
<deletedAxiom>&apos;negative regulation of transmission of nerve impulse&apos; SubClassOf &apos;negative regulation of signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051673</classIRI>
<classLabel>membrane disruption in another organism</classLabel>
<deletedAxiom>&apos;membrane disruption in another organism&apos; SubClassOf &apos;modulation of process of another organism&apos;</deletedAxiom>
<newAxiom>&apos;membrane disruption in another organism&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140975</newAxiom>
<newAxiom>&apos;membrane disruption in another organism&apos; SubClassOf &apos;modification by symbiont of host cell membrane&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090680</classIRI>
<classLabel>disruption by virus of host outer membrane</classLabel>
<deletedAxiom>&apos;disruption by virus of host outer membrane&apos; SubClassOf &apos;disruption by virus of host cell membrane&apos;</deletedAxiom>
<newAxiom>&apos;disruption by virus of host outer membrane&apos; SubClassOf &apos;has_part&apos; some &apos;membrane disruption in another organism&apos;</newAxiom>
<newAxiom>&apos;disruption by virus of host outer membrane&apos; SubClassOf &apos;viral release from host cell by cytolysis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090614</classIRI>
<classLabel>5&apos;-methylthioadenosine deaminase activity</classLabel>
<newAxiom>&apos;5&apos;-methylthioadenosine deaminase activity&apos; SubClassOf &apos;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090613</classIRI>
<classLabel>5&apos;-deoxyadenosine deaminase activity</classLabel>
<newAxiom>&apos;5&apos;-deoxyadenosine deaminase activity&apos; SubClassOf &apos;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090612</classIRI>
<classLabel>cAMP deaminase activity</classLabel>
<newAxiom>&apos;cAMP deaminase activity&apos; SubClassOf &apos;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090559</classIRI>
<classLabel>regulation of membrane permeability</classLabel>
<newAxiom>&apos;regulation of membrane permeability&apos; SubClassOf &apos;regulates characteristic&apos; some &apos;membrane permeability&apos;</newAxiom>
<newAxiom>&apos;regulation of membrane permeability&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates characteristic&apos; some &apos;membrane permeability&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016437</classIRI>
<classLabel>tRNA cytidylyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA cytidylyltransferase activity&apos; SubClassOf &apos;cytidylyltransferase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;tRNA cytidylyltransferase activity&apos; SubClassOf &apos;catalytic activity, acting on a tRNA&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903779</classIRI>
<classLabel>regulation of cardiac conduction</classLabel>
<deletedAxiom>&apos;regulation of cardiac conduction&apos; SubClassOf &apos;regulation of signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903781</classIRI>
<classLabel>positive regulation of cardiac conduction</classLabel>
<deletedAxiom>&apos;positive regulation of cardiac conduction&apos; SubClassOf &apos;positive regulation of signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cardiac conduction&apos; SubClassOf &apos;positive regulation of multicellular organismal process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of cardiac conduction&apos; SubClassOf &apos;positive regulation of biological process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903780</classIRI>
<classLabel>negative regulation of cardiac conduction</classLabel>
<deletedAxiom>&apos;negative regulation of cardiac conduction&apos; SubClassOf &apos;negative regulation of multicellular organismal process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cardiac conduction&apos; SubClassOf &apos;negative regulation of signaling&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of cardiac conduction&apos; SubClassOf &apos;negative regulation of biological process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090225</classIRI>
<classLabel>regulation of spindle density</classLabel>
<deletedAxiom>&apos;regulation of spindle density&apos; SubClassOf &apos;regulates characteristic&apos; some &apos;spindle density&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of spindle density&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates characteristic&apos; some &apos;spindle density&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of spindle density&apos; SubClassOf &apos;regulation of spindle organization&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of spindle density&apos; SubClassOf &apos;regulation of biological quality&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072357</classIRI>
<classLabel>PTW/PP1 phosphatase complex</classLabel>
<deletedAxiom>&apos;PTW/PP1 phosphatase complex&apos; SubClassOf &apos;protein serine/threonine phosphatase complex&apos;</deletedAxiom>
<newAxiom>&apos;PTW/PP1 phosphatase complex&apos; SubClassOf &apos;protein phosphatase type 1 complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052929</classIRI>
<classLabel>ATP:3&apos;-cytidine-cytidine-tRNA adenylyltransferase activity</classLabel>
<deletedAxiom>&apos;ATP:3&apos;-cytidine-cytidine-tRNA adenylyltransferase activity&apos; SubClassOf &apos;tRNA adenylyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;ATP:3&apos;-cytidine-cytidine-tRNA adenylyltransferase activity&apos; SubClassOf &apos;nucleotidyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052928</classIRI>
<classLabel>CTP:3&apos;-cytidine-tRNA cytidylyltransferase activity</classLabel>
<deletedAxiom>&apos;CTP:3&apos;-cytidine-tRNA cytidylyltransferase activity&apos; SubClassOf &apos;catalytic activity, acting on a tRNA&apos;</deletedAxiom>
<deletedAxiom>&apos;CTP:3&apos;-cytidine-tRNA cytidylyltransferase activity&apos; SubClassOf &apos;nucleotidyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062154</classIRI>
<classLabel>N6-methyl-AMP deaminase activity</classLabel>
<deletedAxiom>&apos;N6-methyl-AMP deaminase activity&apos; SubClassOf &apos;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052494</classIRI>
<classLabel>occlusion by host of symbiont vascular system</classLabel>
<deletedAxiom>&apos;occlusion by host of symbiont vascular system&apos; SubClassOf &apos;modification by host of symbiont structure&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052496</classIRI>
<classLabel>occlusion by host of symbiont xylem</classLabel>
<deletedAxiom>&apos;occlusion by host of symbiont xylem&apos; SubClassOf &apos;occlusion by host of symbiont vascular system&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042999</classIRI>
<classLabel>regulation of Golgi to plasma membrane CFTR protein transport</classLabel>
<deletedAxiom>&apos;regulation of Golgi to plasma membrane CFTR protein transport&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;Golgi to plasma membrane CFTR protein transport&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of Golgi to plasma membrane CFTR protein transport&apos; SubClassOf &apos;regulates&apos; some &apos;Golgi to plasma membrane CFTR protein transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of Golgi to plasma membrane CFTR protein transport&apos; SubClassOf &apos;regulation of Golgi to plasma membrane protein transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052338</classIRI>
<classLabel>disruption by host of symbiont cell wall</classLabel>
<deletedAxiom>&apos;disruption by host of symbiont cell wall&apos; SubClassOf &apos;modification by host of symbiont cell wall&apos;</deletedAxiom>
<newAxiom>&apos;disruption by host of symbiont cell wall&apos; SubClassOf &apos;modification by host of symbiont structure&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052337</classIRI>
<classLabel>modification by host of symbiont membrane</classLabel>
<deletedAxiom>&apos;modification by host of symbiont membrane&apos; SubClassOf &apos;modification by host of symbiont cellular component&apos;</deletedAxiom>
<newAxiom>&apos;modification by host of symbiont membrane&apos; SubClassOf &apos;modification by host of symbiont structure&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052336</classIRI>
<classLabel>modification by host of symbiont cell wall</classLabel>
<deletedAxiom>&apos;modification by host of symbiont cell wall&apos; SubClassOf &apos;modification by host of symbiont cellular component&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052335</classIRI>
<classLabel>modification by host of symbiont cytoskeleton</classLabel>
<deletedAxiom>&apos;modification by host of symbiont cytoskeleton&apos; SubClassOf &apos;modification by host of symbiont cellular component&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052367</classIRI>
<classLabel>disruption by host of symbiont cellular component</classLabel>
<deletedAxiom>&apos;disruption by host of symbiont cellular component&apos; SubClassOf &apos;modification by host of symbiont cellular component&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052187</classIRI>
<classLabel>modification by host of symbiont cellular component</classLabel>
<deletedAxiom>&apos;modification by host of symbiont cellular component&apos; SubClassOf &apos;modification by host of symbiont structure&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052183</classIRI>
<classLabel>modification by host of symbiont structure</classLabel>
<deletedAxiom>&apos;modification by host of symbiont structure&apos; SubClassOf &apos;modulation by host of symbiont process&apos;</deletedAxiom>
<newAxiom>&apos;modification by host of symbiont structure&apos; SubClassOf &apos;biological process involved in interaction with symbiont&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052039</classIRI>
<classLabel>disruption by symbiont of host cytoskeleton</classLabel>
<deletedAxiom>&apos;disruption by symbiont of host cytoskeleton&apos; SubClassOf &apos;modification by symbiont of host cellular component&apos;</deletedAxiom>
<newAxiom>&apos;disruption by symbiont of host cytoskeleton&apos; SubClassOf &apos;disruption by symbiont of host cellular component&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140847</classIRI>
<classLabel>negative regulation of promoter clearance from RNA polymerase II promoter</classLabel>
<deletedAxiom>&apos;negative regulation of promoter clearance from RNA polymerase II promoter&apos; SubClassOf &apos;biological regulation&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of promoter clearance from RNA polymerase II promoter&apos; SubClassOf &apos;negative regulation of RNA biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;negative regulation of promoter clearance from RNA polymerase II promoter&apos; SubClassOf &apos;regulation of promoter clearance from RNA polymerase II promoter&apos;</newAxiom>
<newAxiom>&apos;negative regulation of promoter clearance from RNA polymerase II promoter&apos; SubClassOf &apos;negatively regulates&apos; some &apos;RNA polymerase II promoter clearance&apos;</newAxiom>
<newAxiom>&apos;negative regulation of promoter clearance from RNA polymerase II promoter&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;RNA polymerase II promoter clearance&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140846</classIRI>
<classLabel>positive regulation of promoter clearance from RNA polymerase II promoter</classLabel>
<deletedAxiom>&apos;positive regulation of promoter clearance from RNA polymerase II promoter&apos; SubClassOf &apos;biological regulation&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of promoter clearance from RNA polymerase II promoter&apos; SubClassOf &apos;regulation of promoter clearance from RNA polymerase II promoter&apos;</newAxiom>
<newAxiom>&apos;positive regulation of promoter clearance from RNA polymerase II promoter&apos; SubClassOf &apos;positive regulation of RNA biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;positive regulation of promoter clearance from RNA polymerase II promoter&apos; SubClassOf &apos;positively regulates&apos; some &apos;RNA polymerase II promoter clearance&apos;</newAxiom>
<newAxiom>&apos;positive regulation of promoter clearance from RNA polymerase II promoter&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;RNA polymerase II promoter clearance&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140845</classIRI>
<classLabel>regulation of promoter clearance from RNA polymerase II promoter</classLabel>
<deletedAxiom>&apos;regulation of promoter clearance from RNA polymerase II promoter&apos; SubClassOf &apos;biological regulation&apos;</deletedAxiom>
<newAxiom>&apos;regulation of promoter clearance from RNA polymerase II promoter&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;RNA polymerase II promoter clearance&apos;)</newAxiom>
<newAxiom>&apos;regulation of promoter clearance from RNA polymerase II promoter&apos; SubClassOf &apos;regulation of RNA biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;regulation of promoter clearance from RNA polymerase II promoter&apos; SubClassOf &apos;regulates&apos; some &apos;RNA polymerase II promoter clearance&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032922</classIRI>
<classLabel>circadian regulation of gene expression</classLabel>
<deletedAxiom>&apos;circadian regulation of gene expression&apos; SubClassOf &apos;multicellular organismal process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140670</classIRI>
<classLabel>ATP-dependent cohesin unloading activity</classLabel>
<deletedAxiom>&apos;ATP-dependent cohesin unloading activity&apos; SubClassOf &apos;ATP-dependent protein-DNA unloading activity&apos;</deletedAxiom>
<newAxiom>&apos;ATP-dependent cohesin unloading activity&apos; SubClassOf &apos;catalytic activity, acting on DNA&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046936</classIRI>
<classLabel>2&apos;-deoxyadenosine deaminase activity</classLabel>
<newAxiom>&apos;2&apos;-deoxyadenosine deaminase activity&apos; SubClassOf &apos;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines&apos;</newAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160049</classIRI>
<classLabel>negative regulation of cGAS/STING signaling pathway</classLabel>
<newAxiom>'negative regulation of cGAS/STING signaling pathway' EquivalentTo 'biological regulation' and ('negatively regulates' some 'cGAS/STING signaling pathway')</newAxiom>
<newAxiom>'negative regulation of cGAS/STING signaling pathway' SubClassOf 'negatively regulates' some 'cGAS/STING signaling pathway'</newAxiom>
<newAxiom>'negative regulation of cGAS/STING signaling pathway' SubClassOf 'negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160054</classIRI>
<classLabel>microfibril assembly</classLabel>
<newAxiom>'microfibril assembly' SubClassOf 'cellular component assembly'</newAxiom>
<newAxiom>'microfibril assembly' SubClassOf 'results in assembly of' some 'microfibril'</newAxiom>
<newAxiom>'microfibril assembly' EquivalentTo 'cellular component assembly' and ('results in assembly of' some 'microfibril')</newAxiom>
<newAxiom>'microfibril assembly' SubClassOf 'supramolecular fiber organization'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160053</classIRI>
<classLabel>serine-based site-specific recombinase activity</classLabel>
<newAxiom>'serine-based site-specific recombinase activity' SubClassOf 'site-specific recombinase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160052</classIRI>
<classLabel>mitotic nuclear envelope segregation</classLabel>
<newAxiom>'mitotic nuclear envelope segregation' SubClassOf 'mitotic cell cycle process'</newAxiom>
<newAxiom>'mitotic nuclear envelope segregation' SubClassOf 'part of' some 'mitotic nuclear division'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160051</classIRI>
<classLabel>Cyc8(Ssn6)-Tup1 general repressor complex</classLabel>
<newAxiom>'Cyc8(Ssn6)-Tup1 general repressor complex' SubClassOf 'RNA polymerase II transcription repressor complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160050</classIRI>
<classLabel>xanthine binding</classLabel>
<newAxiom>'xanthine binding' SubClassOf 'purine nucleobase binding'</newAxiom>
<newAxiom>'xanthine binding' SubClassOf 'has input' some 'xanthine'</newAxiom>
<newAxiom>'xanthine binding' EquivalentTo 'binding' and ('has input' some 'xanthine')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106435</classIRI>
<classLabel>carboxylesterase activity</classLabel>
<newAxiom>'carboxylesterase activity' SubClassOf 'carboxylic ester hydrolase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106434</classIRI>
<classLabel>retinal isomerization</classLabel>
<newAxiom>'retinal isomerization' SubClassOf 'retinal metabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106436</classIRI>
<classLabel>eukaryotic sulfide quinone oxidoreductase activity</classLabel>
<newAxiom>'eukaryotic sulfide quinone oxidoreductase activity' SubClassOf 'oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/RO_0012009</classIRI>
<classLabel>hydrogen peroxide channel activity</classLabel>
<newAxiom>'hydrogen peroxide channel activity' SubClassOf 'part of' some 'hydrogen peroxide transmembrane transport'</newAxiom>
<newAxiom>'hydrogen peroxide channel activity' SubClassOf 'has primary input' some 'hydrogen peroxide'</newAxiom>
<newAxiom>'hydrogen peroxide channel activity' EquivalentTo 'channel activity' and ('has primary input' some 'hydrogen peroxide')</newAxiom>
<newAxiom>'hydrogen peroxide channel activity' SubClassOf 'channel activity'</newAxiom>
<newAxiom>'hydrogen peroxide channel activity' SubClassOf 'inorganic molecular entity transmembrane transporter activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140976</classIRI>
<classLabel>defense response against disruption of plasma membrane integrity</classLabel>
<newAxiom>'defense response against disruption of plasma membrane integrity' SubClassOf 'defense response to other organism'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140975</classIRI>
<classLabel>disruption of cellular component of another organism</classLabel>
<newAxiom>'disruption of cellular component of another organism' SubClassOf 'biological process involved in interspecies interaction between organisms'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140916</classIRI>
<classLabel>zinc ion import into lysosome</classLabel>
<newAxiom>'zinc ion import into lysosome' SubClassOf 'results in transport across' some 'lysosomal membrane'</newAxiom>
<newAxiom>'zinc ion import into lysosome' SubClassOf 'vacuolar transmembrane transport'</newAxiom>
<newAxiom>'zinc ion import into lysosome' SubClassOf 'has target end location' some 'lysosomal lumen'</newAxiom>
<newAxiom>'zinc ion import into lysosome' EquivalentTo 'transport' and ('has target start location' some 'cytosol') and ('has target end location' some 'lysosomal lumen') and ('results in transport across' some 'lysosomal membrane') and ('has primary input' some 'zinc(2+)')</newAxiom>
<newAxiom>'zinc ion import into lysosome' SubClassOf 'lysosomal transport'</newAxiom>
<newAxiom>'zinc ion import into lysosome' SubClassOf 'zinc ion import into organelle'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140915</classIRI>
<classLabel>zinc ion import into zymogen granule</classLabel>
<newAxiom>'zinc ion import into zymogen granule' EquivalentTo 'transport' and ('has target start location' some 'cytosol') and ('has target end location' some 'zymogen granule') and ('results in transport across' some 'zymogen granule membrane') and ('has primary input' some 'zinc(2+)')</newAxiom>
<newAxiom>'zinc ion import into zymogen granule' SubClassOf 'zinc ion import into secretory vesicle'</newAxiom>
<newAxiom>'zinc ion import into zymogen granule' SubClassOf 'has target end location' some 'zymogen granule'</newAxiom>
<newAxiom>'zinc ion import into zymogen granule' SubClassOf 'results in transport across' some 'zymogen granule membrane'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140914</classIRI>
<classLabel>zinc ion import into secretory vesicle</classLabel>
<newAxiom>'zinc ion import into secretory vesicle' SubClassOf 'has target end location' some 'secretory vesicle'</newAxiom>
<newAxiom>'zinc ion import into secretory vesicle' SubClassOf 'zinc ion import into organelle'</newAxiom>
<newAxiom>'zinc ion import into secretory vesicle' EquivalentTo 'transport' and ('has target start location' some 'cytosol') and ('has target end location' some 'secretory vesicle') and ('results in transport across' some 'secretory granule membrane') and ('has primary input' some 'zinc(2+)')</newAxiom>
<newAxiom>'zinc ion import into secretory vesicle' SubClassOf 'results in transport across' some 'secretory granule membrane'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140913</classIRI>
<classLabel>viral release via disruption of host peptidoglycan cell wall</classLabel>
<newAxiom>'viral release via disruption of host peptidoglycan cell wall' SubClassOf 'viral release from host cell by cytolysis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140918</classIRI>
<classLabel>centrosomal core</classLabel>
<newAxiom>'centrosomal core' SubClassOf 'cellular anatomical entity'</newAxiom>
<newAxiom>'centrosomal core' SubClassOf 'part of' some 'centrosome'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140917</classIRI>
<classLabel>zinc ion import into mitochondrion</classLabel>
<newAxiom>'zinc ion import into mitochondrion' SubClassOf 'zinc ion import into organelle'</newAxiom>
<newAxiom>'zinc ion import into mitochondrion' EquivalentTo 'transport' and ('has target start location' some 'cytosol') and ('has target end location' some 'mitochondrial matrix') and ('results in transport across' some 'mitochondrial inner membrane') and ('has primary input' some 'zinc(2+)')</newAxiom>
<newAxiom>'zinc ion import into mitochondrion' SubClassOf 'mitochondrial transmembrane transport'</newAxiom>
<newAxiom>'zinc ion import into mitochondrion' SubClassOf 'results in transport across' some 'mitochondrial inner membrane'</newAxiom>
<newAxiom>'zinc ion import into mitochondrion' SubClassOf 'has target end location' some 'mitochondrial matrix'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>