<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
638
</numberChangedClasses>
<numberNewClasses>
14
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044222</classIRI>
<classLabel>anammoxosome</classLabel>
<newAxiom>&apos;anammoxosome&apos; SubClassOf &apos;in taxon&apos; only &apos;Prokaryota&apos;</newAxiom>
<newAxiom>&apos;anammoxosome&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Prokaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044227</classIRI>
<classLabel>methane-oxidizing organelle</classLabel>
<newAxiom>&apos;methane-oxidizing organelle&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Prokaryota&apos;</newAxiom>
<newAxiom>&apos;methane-oxidizing organelle&apos; SubClassOf &apos;in taxon&apos; only &apos;Prokaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009847</classIRI>
<classLabel>spore germination</classLabel>
<deletedAxiom>&apos;spore germination&apos; SubClassOf &apos;cell differentiation&apos;</deletedAxiom>
<newAxiom>&apos;spore germination&apos; SubClassOf &apos;cellular developmental process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034775</classIRI>
<classLabel>glutathione transmembrane transport</classLabel>
<deletedAxiom>&apos;glutathione transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010700</classIRI>
<classLabel>negative regulation of norepinephrine secretion</classLabel>
<deletedAxiom>&apos;negative regulation of norepinephrine secretion&apos; SubClassOf &apos;negative regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010701</classIRI>
<classLabel>positive regulation of norepinephrine secretion</classLabel>
<deletedAxiom>&apos;positive regulation of norepinephrine secretion&apos; SubClassOf &apos;positive regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000969</classIRI>
<classLabel>positive regulation of AMPA receptor activity</classLabel>
<deletedAxiom>&apos;positive regulation of AMPA receptor activity&apos; SubClassOf &apos;positive regulation of cation channel activity&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of AMPA receptor activity&apos; SubClassOf &apos;positive regulation of ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034755</classIRI>
<classLabel>iron ion transmembrane transport</classLabel>
<newAxiom>&apos;iron ion transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0020022</classIRI>
<classLabel>acidocalcisome</classLabel>
<newAxiom>&apos;acidocalcisome&apos; SubClassOf &apos;in taxon&apos; some (not (&apos;Ascomycota&apos;))</newAxiom>
<newAxiom>&apos;acidocalcisome&apos; DisjointWith &apos;in taxon&apos; some &apos;Ascomycota&apos;</newAxiom>
<newAxiom>&apos;acidocalcisome&apos; SubClassOf not (&apos;in taxon&apos; some &apos;Ascomycota&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009669</classIRI>
<classLabel>sucrose:cation symporter activity</classLabel>
<deletedAxiom>&apos;sucrose:cation symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;sucrose&apos;) and (&apos;has primary input&apos; some &apos;inorganic cation&apos;)</deletedAxiom>
<newAxiom>&apos;sucrose:cation symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;sucrose&apos;) and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009671</classIRI>
<classLabel>nitrate:proton symporter activity</classLabel>
<deletedAxiom>&apos;nitrate:proton symporter activity&apos; SubClassOf &apos;anion:cation symporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010597</classIRI>
<classLabel>green leaf volatile biosynthetic process</classLabel>
<newAxiom>&apos;green leaf volatile biosynthetic process&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Viridiplantae&apos;</newAxiom>
<newAxiom>&apos;green leaf volatile biosynthetic process&apos; SubClassOf &apos;in taxon&apos; only &apos;Viridiplantae&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009504</classIRI>
<classLabel>cell plate</classLabel>
<newAxiom>&apos;cell plate&apos; SubClassOf &apos;in taxon&apos; only &apos;Viridiplantae&apos;</newAxiom>
<newAxiom>&apos;cell plate&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Viridiplantae&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009524</classIRI>
<classLabel>phragmoplast</classLabel>
<newAxiom>&apos;phragmoplast&apos; SubClassOf &apos;in taxon&apos; only &apos;Viridiplantae&apos;</newAxiom>
<newAxiom>&apos;phragmoplast&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Viridiplantae&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034446</classIRI>
<classLabel>substrate adhesion-dependent cell spreading</classLabel>
<deletedAxiom>&apos;substrate adhesion-dependent cell spreading&apos; SubClassOf &apos;cell morphogenesis involved in differentiation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010486</classIRI>
<classLabel>manganese:proton antiporter activity</classLabel>
<deletedAxiom>&apos;manganese:proton antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;manganese cation&apos;)</deletedAxiom>
<newAxiom>&apos;manganese:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;manganese cation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009359</classIRI>
<classLabel>type II site-specific deoxyribonuclease complex</classLabel>
<newAxiom>&apos;type II site-specific deoxyribonuclease complex&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Prokaryota&apos;</newAxiom>
<newAxiom>&apos;type II site-specific deoxyribonuclease complex&apos; SubClassOf &apos;in taxon&apos; only &apos;Prokaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010348</classIRI>
<classLabel>lithium:proton antiporter activity</classLabel>
<deletedAxiom>&apos;lithium:proton antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;lithium(1+)&apos;)</deletedAxiom>
<newAxiom>&apos;lithium:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;lithium(1+)&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034307</classIRI>
<classLabel>regulation of ascospore formation</classLabel>
<newAxiom>&apos;regulation of ascospore formation&apos; SubClassOf &apos;regulation of cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034220</classIRI>
<classLabel>ion transmembrane transport</classLabel>
<deletedAxiom>&apos;ion transmembrane transport&apos; EquivalentTo &apos;transport&apos; and (&apos;results in transport across&apos; some &apos;membrane&apos;) and (&apos;has primary input&apos; some &apos;ion&apos;)</deletedAxiom>
<newAxiom>&apos;ion transmembrane transport&apos; EquivalentTo &apos;transport&apos; and (&apos;results in transport across&apos; some &apos;membrane&apos;) and (&apos;has primary input&apos; some &apos;monoatomic ion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010292</classIRI>
<classLabel>GTP:GDP antiporter activity</classLabel>
<deletedAxiom>&apos;GTP:GDP antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;GTP:GDP antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;GTP:GDP antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010143</classIRI>
<classLabel>cutin biosynthetic process</classLabel>
<newAxiom>&apos;cutin biosynthetic process&apos; SubClassOf &apos;part of&apos; some http://purl.obolibrary.org/obo/GO_0160062</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097638</classIRI>
<classLabel>L-arginine import across plasma membrane</classLabel>
<deletedAxiom>&apos;L-arginine import across plasma membrane&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;L-arginine import across plasma membrane&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097603</classIRI>
<classLabel>temperature-gated ion channel activity</classLabel>
<deletedAxiom>&apos;temperature-gated ion channel activity&apos; SubClassOf &apos;gated channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;temperature-gated ion channel activity&apos; SubClassOf &apos;ion channel activity&apos;</deletedAxiom>
<newAxiom>&apos;temperature-gated ion channel activity&apos; SubClassOf &apos;ion gated channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097604</classIRI>
<classLabel>temperature-gated cation channel activity</classLabel>
<deletedAxiom>&apos;temperature-gated cation channel activity&apos; EquivalentTo &apos;temperature-gated ion channel activity&apos; and (&apos;has primary input&apos; some &apos;inorganic cation&apos;)</deletedAxiom>
<newAxiom>&apos;temperature-gated cation channel activity&apos; EquivalentTo &apos;temperature-gated ion channel activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000514</classIRI>
<classLabel>3-sulfino-L-alanine: proton, glutamate antiporter activity</classLabel>
<deletedAxiom>&apos;3-sulfino-L-alanine: proton, glutamate antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;3-sulfino-L-alanine: proton, glutamate antiporter activity&apos; SubClassOf &apos;acidic amino acid transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;3-sulfino-L-alanine: proton, glutamate antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;3-sulfino-L-alanine: proton, glutamate antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;glutamate(1-)&apos;) and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;3-sulfino-L-alanine(1-)&apos;)</deletedAxiom>
<newAxiom>&apos;3-sulfino-L-alanine: proton, glutamate antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;glutamate(1-)&apos;) and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;3-sulfino-L-alanine(1-)&apos;)</newAxiom>
<newAxiom>&apos;3-sulfino-L-alanine: proton, glutamate antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000515</classIRI>
<classLabel>aspartate:glutamate, proton antiporter activity</classLabel>
<deletedAxiom>&apos;aspartate:glutamate, proton antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;aspartate:glutamate, proton antiporter activity&apos; SubClassOf &apos;acidic amino acid transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;aspartate:glutamate, proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;aspartate:glutamate, proton antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;glutamate(1-)&apos;) and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;aspartate(1-)&apos;)</deletedAxiom>
<newAxiom>&apos;aspartate:glutamate, proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;glutamate(1-)&apos;) and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;aspartate(1-)&apos;)</newAxiom>
<newAxiom>&apos;aspartate:glutamate, proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048502</classIRI>
<classLabel>ABC-type thiamine transporter activity</classLabel>
<deletedAxiom>&apos;ABC-type thiamine transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000119</classIRI>
<classLabel>negative regulation of sodium-dependent phosphate transport</classLabel>
<deletedAxiom>&apos;negative regulation of sodium-dependent phosphate transport&apos; SubClassOf &apos;negative regulation of anion transport&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of sodium-dependent phosphate transport&apos; SubClassOf &apos;negative regulation of transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000120</classIRI>
<classLabel>positive regulation of sodium-dependent phosphate transport</classLabel>
<deletedAxiom>&apos;positive regulation of sodium-dependent phosphate transport&apos; SubClassOf &apos;positive regulation of anion transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of sodium-dependent phosphate transport&apos; SubClassOf &apos;positive regulation of transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097339</classIRI>
<classLabel>glycolate transmembrane transport</classLabel>
<deletedAxiom>&apos;glycolate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000486</classIRI>
<classLabel>negative regulation of glutamine transport</classLabel>
<deletedAxiom>&apos;negative regulation of glutamine transport&apos; SubClassOf &apos;negative regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000487</classIRI>
<classLabel>positive regulation of glutamine transport</classLabel>
<deletedAxiom>&apos;positive regulation of glutamine transport&apos; SubClassOf &apos;positive regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000485</classIRI>
<classLabel>regulation of glutamine transport</classLabel>
<deletedAxiom>&apos;regulation of glutamine transport&apos; SubClassOf &apos;regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000453</classIRI>
<classLabel>enzyme-directed rRNA 2&apos;-O-methylation</classLabel>
<deletedAxiom>&apos;enzyme-directed rRNA 2&apos;-O-methylation&apos; SubClassOf &apos;rRNA 2&apos;-O-methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000310</classIRI>
<classLabel>regulation of NMDA receptor activity</classLabel>
<deletedAxiom>&apos;regulation of NMDA receptor activity&apos; SubClassOf &apos;regulation of cation channel activity&apos;</deletedAxiom>
<newAxiom>&apos;regulation of NMDA receptor activity&apos; SubClassOf &apos;regulation of ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000311</classIRI>
<classLabel>regulation of AMPA receptor activity</classLabel>
<deletedAxiom>&apos;regulation of AMPA receptor activity&apos; SubClassOf &apos;regulation of cation channel activity&apos;</deletedAxiom>
<newAxiom>&apos;regulation of AMPA receptor activity&apos; SubClassOf &apos;regulation of ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097297</classIRI>
<classLabel>activation of cysteine-type endopeptidase activity involved in execution phase of apoptosis</classLabel>
<deletedAxiom>&apos;activation of cysteine-type endopeptidase activity involved in execution phase of apoptosis&apos; SubClassOf &apos;positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097272</classIRI>
<classLabel>ammonium homeostasis</classLabel>
<deletedAxiom>&apos;ammonium homeostasis&apos; SubClassOf &apos;monovalent inorganic cation homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;ammonium homeostasis&apos; SubClassOf &apos;inorganic ion homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097273</classIRI>
<classLabel>creatinine homeostasis</classLabel>
<deletedAxiom>&apos;creatinine homeostasis&apos; SubClassOf &apos;chemical homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;creatinine homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;creatinine&apos;</deletedAxiom>
<deletedAxiom>&apos;creatinine homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;creatinine&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097274</classIRI>
<classLabel>urea homeostasis</classLabel>
<deletedAxiom>&apos;urea homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;urea&apos;)</deletedAxiom>
<deletedAxiom>&apos;urea homeostasis&apos; SubClassOf &apos;chemical homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;urea homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;urea&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097275</classIRI>
<classLabel>cellular ammonium homeostasis</classLabel>
<deletedAxiom>&apos;cellular ammonium homeostasis&apos; SubClassOf &apos;cellular monovalent inorganic cation homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;cellular ammonium homeostasis&apos; SubClassOf &apos;cellular chemical homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097276</classIRI>
<classLabel>cellular creatinine homeostasis</classLabel>
<deletedAxiom>&apos;cellular creatinine homeostasis&apos; EquivalentTo &apos;cellular chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;creatinine&apos;)</deletedAxiom>
<deletedAxiom>&apos;cellular creatinine homeostasis&apos; SubClassOf &apos;cellular chemical homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular creatinine homeostasis&apos; SubClassOf &apos;creatinine homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097277</classIRI>
<classLabel>cellular urea homeostasis</classLabel>
<deletedAxiom>&apos;cellular urea homeostasis&apos; EquivalentTo &apos;cellular chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;urea&apos;)</deletedAxiom>
<deletedAxiom>&apos;cellular urea homeostasis&apos; SubClassOf &apos;cellular chemical homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular urea homeostasis&apos; SubClassOf &apos;urea homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000297</classIRI>
<classLabel>spermine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;spermine transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000296</classIRI>
<classLabel>spermine transport</classLabel>
<deletedAxiom>&apos;spermine transport&apos; SubClassOf &apos;cation transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000236</classIRI>
<classLabel>mitotic prometaphase</classLabel>
<deletedAxiom>&apos;mitotic prometaphase&apos; SubClassOf &apos;mitotic cell cycle phase&apos;</deletedAxiom>
<newAxiom>&apos;mitotic prometaphase&apos; SubClassOf &apos;mitotic M phase&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000227</classIRI>
<classLabel>oxaloacetate secondary active transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;oxaloacetate secondary active transmembrane transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097080</classIRI>
<classLabel>plasma membrane selenite transport</classLabel>
<deletedAxiom>&apos;plasma membrane selenite transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;plasma membrane selenite transport&apos; SubClassOf &apos;transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097056</classIRI>
<classLabel>selenocysteinyl-tRNA(Sec) biosynthetic process</classLabel>
<deletedAxiom>&apos;selenocysteinyl-tRNA(Sec) biosynthetic process&apos; SubClassOf &apos;has primary output&apos; some &apos;Sec-tRNA(Sec)&apos;</deletedAxiom>
<deletedAxiom>&apos;selenocysteinyl-tRNA(Sec) biosynthetic process&apos; SubClassOf &apos;RNA biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;selenocysteinyl-tRNA(Sec) biosynthetic process&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some &apos;Sec-tRNA(Sec)&apos;)</deletedAxiom>
<deletedAxiom>&apos;selenocysteinyl-tRNA(Sec) biosynthetic process&apos; SubClassOf &apos;tRNA metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000102</classIRI>
<classLabel>L-methionine secondary active transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;L-methionine secondary active transmembrane transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097079</classIRI>
<classLabel>selenite:proton symporter activity</classLabel>
<deletedAxiom>&apos;selenite:proton symporter activity&apos; SubClassOf &apos;anion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000064</classIRI>
<classLabel>L-ornithine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;L-ornithine transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905735</classIRI>
<classLabel>regulation of L-proline import across plasma membrane</classLabel>
<deletedAxiom>&apos;regulation of L-proline import across plasma membrane&apos; SubClassOf &apos;regulation of anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of L-proline import across plasma membrane&apos; SubClassOf &apos;regulation of cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905736</classIRI>
<classLabel>negative regulation of L-proline import across plasma membrane</classLabel>
<deletedAxiom>&apos;negative regulation of L-proline import across plasma membrane&apos; SubClassOf &apos;negative regulation of cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of L-proline import across plasma membrane&apos; SubClassOf &apos;negative regulation of anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905737</classIRI>
<classLabel>positive regulation of L-proline import across plasma membrane</classLabel>
<deletedAxiom>&apos;positive regulation of L-proline import across plasma membrane&apos; SubClassOf &apos;positive regulation of cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of L-proline import across plasma membrane&apos; SubClassOf &apos;positive regulation of anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004971</classIRI>
<classLabel>AMPA glutamate receptor activity</classLabel>
<deletedAxiom>&apos;AMPA glutamate receptor activity&apos; SubClassOf &apos;ligand-gated cation channel activity&apos;</deletedAxiom>
<newAxiom>&apos;AMPA glutamate receptor activity&apos; SubClassOf &apos;inorganic cation transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004972</classIRI>
<classLabel>NMDA glutamate receptor activity</classLabel>
<deletedAxiom>&apos;NMDA glutamate receptor activity&apos; SubClassOf &apos;voltage-gated cation channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;NMDA glutamate receptor activity&apos; SubClassOf &apos;ligand-gated cation channel activity&apos;</deletedAxiom>
<newAxiom>&apos;NMDA glutamate receptor activity&apos; SubClassOf &apos;voltage-gated ion channel activity&apos;</newAxiom>
<newAxiom>&apos;NMDA glutamate receptor activity&apos; SubClassOf &apos;inorganic cation transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905948</classIRI>
<classLabel>ABC-type 3&apos;,5&apos;-cyclic GMP transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;ABC-type 3&apos;,5&apos;-cyclic GMP transmembrane transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014049</classIRI>
<classLabel>positive regulation of glutamate secretion</classLabel>
<deletedAxiom>&apos;positive regulation of glutamate secretion&apos; SubClassOf &apos;positive regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014048</classIRI>
<classLabel>regulation of glutamate secretion</classLabel>
<deletedAxiom>&apos;regulation of glutamate secretion&apos; SubClassOf &apos;regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014058</classIRI>
<classLabel>negative regulation of acetylcholine secretion, neurotransmission</classLabel>
<deletedAxiom>&apos;negative regulation of acetylcholine secretion, neurotransmission&apos; SubClassOf &apos;negative regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014059</classIRI>
<classLabel>regulation of dopamine secretion</classLabel>
<deletedAxiom>&apos;regulation of dopamine secretion&apos; SubClassOf &apos;regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014056</classIRI>
<classLabel>regulation of acetylcholine secretion, neurotransmission</classLabel>
<deletedAxiom>&apos;regulation of acetylcholine secretion, neurotransmission&apos; SubClassOf &apos;regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014057</classIRI>
<classLabel>positive regulation of acetylcholine secretion, neurotransmission</classLabel>
<deletedAxiom>&apos;positive regulation of acetylcholine secretion, neurotransmission&apos; SubClassOf &apos;positive regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014054</classIRI>
<classLabel>positive regulation of gamma-aminobutyric acid secretion</classLabel>
<deletedAxiom>&apos;positive regulation of gamma-aminobutyric acid secretion&apos; SubClassOf &apos;positive regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014052</classIRI>
<classLabel>regulation of gamma-aminobutyric acid secretion</classLabel>
<deletedAxiom>&apos;regulation of gamma-aminobutyric acid secretion&apos; SubClassOf &apos;regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014053</classIRI>
<classLabel>negative regulation of gamma-aminobutyric acid secretion</classLabel>
<deletedAxiom>&apos;negative regulation of gamma-aminobutyric acid secretion&apos; SubClassOf &apos;negative regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014050</classIRI>
<classLabel>negative regulation of glutamate secretion</classLabel>
<deletedAxiom>&apos;negative regulation of glutamate secretion&apos; SubClassOf &apos;negative regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014061</classIRI>
<classLabel>regulation of norepinephrine secretion</classLabel>
<deletedAxiom>&apos;regulation of norepinephrine secretion&apos; SubClassOf &apos;regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038055</classIRI>
<classLabel>BMP secretion</classLabel>
<newAxiom>&apos;BMP secretion&apos; SubClassOf &apos;in taxon&apos; some (not (&apos;Fungi or Bacteria or Archaea&apos;))</newAxiom>
<newAxiom>&apos;BMP secretion&apos; DisjointWith &apos;in taxon&apos; some &apos;Fungi or Bacteria or Archaea&apos;</newAxiom>
<newAxiom>&apos;BMP secretion&apos; SubClassOf not (&apos;in taxon&apos; some &apos;Fungi or Bacteria or Archaea&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901034</classIRI>
<classLabel>regulation of L-glutamine import across plasma membrane</classLabel>
<deletedAxiom>&apos;regulation of L-glutamine import across plasma membrane&apos; SubClassOf &apos;regulation of anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of L-glutamine import across plasma membrane&apos; SubClassOf &apos;regulation of cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901035</classIRI>
<classLabel>negative regulation of L-glutamine import across plasma membrane</classLabel>
<deletedAxiom>&apos;negative regulation of L-glutamine import across plasma membrane&apos; SubClassOf &apos;negative regulation of cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of L-glutamine import across plasma membrane&apos; SubClassOf &apos;negative regulation of anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of L-glutamine import across plasma membrane&apos; SubClassOf &apos;negative regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901036</classIRI>
<classLabel>positive regulation of L-glutamine import across plasma membrane</classLabel>
<deletedAxiom>&apos;positive regulation of L-glutamine import across plasma membrane&apos; SubClassOf &apos;positive regulation of anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of L-glutamine import across plasma membrane&apos; SubClassOf &apos;positive regulation of cation transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of L-glutamine import across plasma membrane&apos; SubClassOf &apos;positive regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043940</classIRI>
<classLabel>regulation of sexual sporulation resulting in formation of a cellular spore</classLabel>
<deletedAxiom>&apos;regulation of sexual sporulation resulting in formation of a cellular spore&apos; SubClassOf &apos;regulation of cell cycle process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043941</classIRI>
<classLabel>positive regulation of sexual sporulation resulting in formation of a cellular spore</classLabel>
<deletedAxiom>&apos;positive regulation of sexual sporulation resulting in formation of a cellular spore&apos; SubClassOf &apos;positive regulation of cell cycle process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043942</classIRI>
<classLabel>negative regulation of sexual sporulation resulting in formation of a cellular spore</classLabel>
<deletedAxiom>&apos;negative regulation of sexual sporulation resulting in formation of a cellular spore&apos; SubClassOf &apos;negative regulation of cell cycle process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043935</classIRI>
<classLabel>sexual sporulation resulting in formation of a cellular spore</classLabel>
<deletedAxiom>&apos;sexual sporulation resulting in formation of a cellular spore&apos; SubClassOf &apos;meiotic cell cycle process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901349</classIRI>
<classLabel>glucosinolate transport</classLabel>
<deletedAxiom>&apos;glucosinolate transport&apos; SubClassOf &apos;anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901242</classIRI>
<classLabel>ABC-type doxorubicin transporter activity</classLabel>
<deletedAxiom>&apos;ABC-type doxorubicin transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043872</classIRI>
<classLabel>lysine:cadaverine antiporter activity</classLabel>
<deletedAxiom>&apos;lysine:cadaverine antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;lysine:cadaverine antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;lysine:cadaverine antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043865</classIRI>
<classLabel>methionine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;methionine transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043861</classIRI>
<classLabel>agmatine:putrescine antiporter activity</classLabel>
<deletedAxiom>&apos;agmatine:putrescine antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;agmatine:putrescine antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043862</classIRI>
<classLabel>arginine:agmatine antiporter activity</classLabel>
<deletedAxiom>&apos;arginine:agmatine antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;arginine:agmatine antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;arginine:agmatine antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043855</classIRI>
<classLabel>cyclic nucleotide-gated ion channel activity</classLabel>
<deletedAxiom>&apos;cyclic nucleotide-gated ion channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;regulated by&apos; some &apos;cyclic nucleotide binding&apos;) and (&apos;has primary input&apos; some &apos;ion&apos;)</deletedAxiom>
<newAxiom>&apos;cyclic nucleotide-gated ion channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;regulated by&apos; some &apos;cyclic nucleotide binding&apos;) and (&apos;has primary input&apos; some &apos;monoatomic ion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043858</classIRI>
<classLabel>arginine:ornithine antiporter activity</classLabel>
<deletedAxiom>&apos;arginine:ornithine antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;arginine:ornithine antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;arginine:ornithine antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043893</classIRI>
<classLabel>acetate:cation symporter activity</classLabel>
<deletedAxiom>&apos;acetate:cation symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;acetate&apos;) and (&apos;has primary input&apos; some &apos;inorganic cation&apos;)</deletedAxiom>
<newAxiom>&apos;acetate:cation symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;) and (&apos;has primary input&apos; some &apos;acetate&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901553</classIRI>
<classLabel>malonic acid transmembrane transport</classLabel>
<deletedAxiom>&apos;malonic acid transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901475</classIRI>
<classLabel>pyruvate transmembrane transport</classLabel>
<deletedAxiom>&apos;pyruvate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004087</classIRI>
<classLabel>carbamoyl-phosphate synthase (ammonia) activity</classLabel>
<deletedAxiom>&apos;carbamoyl-phosphate synthase (ammonia) activity&apos; SubClassOf &apos;has_participant&apos; some &apos;water&apos;</deletedAxiom>
<deletedAxiom>&apos;carbamoyl-phosphate synthase (ammonia) activity&apos; SubClassOf &apos;has_participant&apos; some &apos;carbon dioxide&apos;</deletedAxiom>
<newAxiom>&apos;carbamoyl-phosphate synthase (ammonia) activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydrogencarbonate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901683</classIRI>
<classLabel>arsenate ion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;arsenate ion transmembrane transporter activity&apos; SubClassOf &apos;anion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;arsenate ion transmembrane transporter activity&apos; SubClassOf &apos;transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901684</classIRI>
<classLabel>arsenate ion transmembrane transport</classLabel>
<deletedAxiom>&apos;arsenate ion transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;arsenate ion transmembrane transport&apos; SubClassOf &apos;transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043299</classIRI>
<classLabel>leukocyte degranulation</classLabel>
<newAxiom>&apos;leukocyte degranulation&apos; SubClassOf &apos;in taxon&apos; only &apos;Vertebrata vertebrates&apos;</newAxiom>
<newAxiom>&apos;leukocyte degranulation&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Vertebrata vertebrates&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901962</classIRI>
<classLabel>S-adenosyl-L-methionine transmembrane transport</classLabel>
<deletedAxiom>&apos;S-adenosyl-L-methionine transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;S-adenosyl-L-methionine transmembrane transport&apos; SubClassOf &apos;transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043225</classIRI>
<classLabel>ATPase-coupled inorganic anion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;ATPase-coupled inorganic anion transmembrane transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;ATPase-coupled inorganic anion transmembrane transporter activity&apos; SubClassOf &apos;part of&apos; some &apos;anion transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033683</classIRI>
<classLabel>nucleotide-excision repair, DNA incision</classLabel>
<deletedAxiom>&apos;nucleotide-excision repair, DNA incision&apos; EquivalentTo &apos;nucleic acid phosphodiester bond hydrolysis&apos; and (&apos;part of&apos; some &apos;nucleotide-excision repair&apos;)</deletedAxiom>
<deletedAxiom>&apos;nucleotide-excision repair, DNA incision&apos; SubClassOf &apos;nucleic acid phosphodiester bond hydrolysis&apos;</deletedAxiom>
<deletedAxiom>&apos;nucleotide-excision repair, DNA incision&apos; SubClassOf &apos;part of&apos; some &apos;nucleotide-excision repair&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033602</classIRI>
<classLabel>negative regulation of dopamine secretion</classLabel>
<deletedAxiom>&apos;negative regulation of dopamine secretion&apos; SubClassOf &apos;negative regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033603</classIRI>
<classLabel>positive regulation of dopamine secretion</classLabel>
<deletedAxiom>&apos;positive regulation of dopamine secretion&apos; SubClassOf &apos;positive regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070588</classIRI>
<classLabel>calcium ion transmembrane transport</classLabel>
<newAxiom>&apos;calcium ion transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070574</classIRI>
<classLabel>cadmium ion transmembrane transport</classLabel>
<newAxiom>&apos;cadmium ion transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900923</classIRI>
<classLabel>regulation of glycine import across plasma membrane</classLabel>
<deletedAxiom>&apos;regulation of glycine import across plasma membrane&apos; SubClassOf &apos;regulation of anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of glycine import across plasma membrane&apos; SubClassOf &apos;regulation of cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900924</classIRI>
<classLabel>negative regulation of glycine import across plasma membrane</classLabel>
<deletedAxiom>&apos;negative regulation of glycine import across plasma membrane&apos; SubClassOf &apos;negative regulation of anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of glycine import across plasma membrane&apos; SubClassOf &apos;negative regulation of cation transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of glycine import across plasma membrane&apos; SubClassOf &apos;negative regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900925</classIRI>
<classLabel>positive regulation of glycine import across plasma membrane</classLabel>
<deletedAxiom>&apos;positive regulation of glycine import across plasma membrane&apos; SubClassOf &apos;positive regulation of anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of glycine import across plasma membrane&apos; SubClassOf &apos;positive regulation of cation transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of glycine import across plasma membrane&apos; SubClassOf &apos;positive regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900926</classIRI>
<classLabel>regulation of L-threonine import across plasma membrane</classLabel>
<deletedAxiom>&apos;regulation of L-threonine import across plasma membrane&apos; SubClassOf &apos;regulation of cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of L-threonine import across plasma membrane&apos; SubClassOf &apos;regulation of anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900927</classIRI>
<classLabel>negative regulation of L-threonine import across plasma membrane</classLabel>
<deletedAxiom>&apos;negative regulation of L-threonine import across plasma membrane&apos; SubClassOf &apos;negative regulation of cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of L-threonine import across plasma membrane&apos; SubClassOf &apos;negative regulation of anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of L-threonine import across plasma membrane&apos; SubClassOf &apos;negative regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900928</classIRI>
<classLabel>positive regulation of L-threonine import across plasma membrane</classLabel>
<deletedAxiom>&apos;positive regulation of L-threonine import across plasma membrane&apos; SubClassOf &apos;positive regulation of anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of L-threonine import across plasma membrane&apos; SubClassOf &apos;positive regulation of cation transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of L-threonine import across plasma membrane&apos; SubClassOf &apos;positive regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900929</classIRI>
<classLabel>regulation of L-tyrosine import across plasma membrane</classLabel>
<deletedAxiom>&apos;regulation of L-tyrosine import across plasma membrane&apos; SubClassOf &apos;regulation of anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of L-tyrosine import across plasma membrane&apos; SubClassOf &apos;regulation of cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900930</classIRI>
<classLabel>negative regulation of L-tyrosine import across plasma membrane</classLabel>
<deletedAxiom>&apos;negative regulation of L-tyrosine import across plasma membrane&apos; SubClassOf &apos;negative regulation of cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of L-tyrosine import across plasma membrane&apos; SubClassOf &apos;negative regulation of anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of L-tyrosine import across plasma membrane&apos; SubClassOf &apos;negative regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900931</classIRI>
<classLabel>positive regulation of L-tyrosine import across plasma membrane</classLabel>
<deletedAxiom>&apos;positive regulation of L-tyrosine import across plasma membrane&apos; SubClassOf &apos;positive regulation of cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of L-tyrosine import across plasma membrane&apos; SubClassOf &apos;positive regulation of anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of L-tyrosine import across plasma membrane&apos; SubClassOf &apos;positive regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045321</classIRI>
<classLabel>leukocyte activation</classLabel>
<newAxiom>&apos;leukocyte activation&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Vertebrata vertebrates&apos;</newAxiom>
<newAxiom>&apos;leukocyte activation&apos; SubClassOf &apos;in taxon&apos; only &apos;Vertebrata vertebrates&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035873</classIRI>
<classLabel>lactate transmembrane transport</classLabel>
<deletedAxiom>&apos;lactate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070218</classIRI>
<classLabel>sulfide ion homeostasis</classLabel>
<deletedAxiom>&apos;sulfide ion homeostasis&apos; SubClassOf &apos;divalent inorganic anion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;sulfide ion homeostasis&apos; SubClassOf &apos;monovalent inorganic anion homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;sulfide ion homeostasis&apos; SubClassOf &apos;inorganic ion homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070219</classIRI>
<classLabel>cellular sulfide ion homeostasis</classLabel>
<deletedAxiom>&apos;cellular sulfide ion homeostasis&apos; SubClassOf &apos;cellular divalent inorganic anion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular sulfide ion homeostasis&apos; SubClassOf &apos;cellular monovalent inorganic anion homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;cellular sulfide ion homeostasis&apos; SubClassOf &apos;cellular chemical homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035784</classIRI>
<classLabel>nickel cation homeostasis</classLabel>
<deletedAxiom>&apos;nickel cation homeostasis&apos; SubClassOf &apos;divalent inorganic cation homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035785</classIRI>
<classLabel>cellular nickel ion homeostasis</classLabel>
<deletedAxiom>&apos;cellular nickel ion homeostasis&apos; SubClassOf &apos;cellular divalent inorganic cation homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045119</classIRI>
<classLabel>azole:proton antiporter activity</classLabel>
<deletedAxiom>&apos;azole:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;azole:proton antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;azole:proton antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
<newAxiom>&apos;azole:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045169</classIRI>
<classLabel>fusome</classLabel>
<newAxiom>&apos;fusome&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eumetazoa&apos;</newAxiom>
<newAxiom>&apos;fusome&apos; SubClassOf &apos;in taxon&apos; only &apos;Eumetazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070089</classIRI>
<classLabel>chloride-activated potassium channel activity</classLabel>
<deletedAxiom>&apos;chloride-activated potassium channel activity&apos; SubClassOf &apos;potassium channel activity&apos;</deletedAxiom>
<newAxiom>&apos;chloride-activated potassium channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;regulated by&apos; some &apos;potassium(1+)&apos;) and (&apos;has primary input&apos; some &apos;chloride&apos;)</newAxiom>
<newAxiom>&apos;chloride-activated potassium channel activity&apos; SubClassOf &apos;regulated by&apos; some &apos;potassium(1+)&apos;</newAxiom>
<newAxiom>&apos;chloride-activated potassium channel activity&apos; SubClassOf &apos;chloride channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035725</classIRI>
<classLabel>sodium ion transmembrane transport</classLabel>
<newAxiom>&apos;sodium ion transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045091</classIRI>
<classLabel>regulation of single stranded viral RNA replication via double stranded DNA intermediate</classLabel>
<newAxiom>&apos;regulation of single stranded viral RNA replication via double stranded DNA intermediate&apos; SubClassOf &apos;regulation of RNA biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035431</classIRI>
<classLabel>negative regulation of gluconate transmembrane transport</classLabel>
<deletedAxiom>&apos;negative regulation of gluconate transmembrane transport&apos; SubClassOf &apos;negative regulation of anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of gluconate transmembrane transport&apos; SubClassOf &apos;negative regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035432</classIRI>
<classLabel>positive regulation of gluconate transmembrane transport</classLabel>
<deletedAxiom>&apos;positive regulation of gluconate transmembrane transport&apos; SubClassOf &apos;positive regulation of anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of gluconate transmembrane transport&apos; SubClassOf &apos;positive regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035430</classIRI>
<classLabel>regulation of gluconate transmembrane transport</classLabel>
<deletedAxiom>&apos;regulation of gluconate transmembrane transport&apos; SubClassOf &apos;regulation of anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;regulation of gluconate transmembrane transport&apos; SubClassOf &apos;regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035436</classIRI>
<classLabel>triose phosphate transmembrane transport</classLabel>
<deletedAxiom>&apos;triose phosphate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;triose phosphate transmembrane transport&apos; SubClassOf &apos;transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035433</classIRI>
<classLabel>acetate transmembrane transport</classLabel>
<deletedAxiom>&apos;acetate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035434</classIRI>
<classLabel>copper ion transmembrane transport</classLabel>
<newAxiom>&apos;copper ion transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035444</classIRI>
<classLabel>nickel cation transmembrane transport</classLabel>
<newAxiom>&apos;nickel cation transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060417</classIRI>
<classLabel>yolk</classLabel>
<newAxiom>&apos;yolk&apos; SubClassOf &apos;in taxon&apos; only &apos;Eumetazoa&apos;</newAxiom>
<newAxiom>&apos;yolk&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eumetazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001909</classIRI>
<classLabel>leukocyte mediated cytotoxicity</classLabel>
<newAxiom>&apos;leukocyte mediated cytotoxicity&apos; SubClassOf &apos;in taxon&apos; only &apos;Vertebrata vertebrates&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035349</classIRI>
<classLabel>coenzyme A transmembrane transport</classLabel>
<deletedAxiom>&apos;coenzyme A transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035350</classIRI>
<classLabel>FAD transmembrane transport</classLabel>
<deletedAxiom>&apos;FAD transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035348</classIRI>
<classLabel>acetyl-CoA transmembrane transport</classLabel>
<deletedAxiom>&apos;acetyl-CoA transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060358</classIRI>
<classLabel>negative regulation of leucine import</classLabel>
<deletedAxiom>&apos;negative regulation of leucine import&apos; SubClassOf &apos;negative regulation of anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of leucine import&apos; SubClassOf &apos;negative regulation of cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060357</classIRI>
<classLabel>regulation of leucine import</classLabel>
<deletedAxiom>&apos;regulation of leucine import&apos; SubClassOf &apos;regulation of cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of leucine import&apos; SubClassOf &apos;regulation of anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035381</classIRI>
<classLabel>ATP-gated ion channel activity</classLabel>
<deletedAxiom>&apos;ATP-gated ion channel activity&apos; SubClassOf &apos;ion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;ATP-gated ion channel activity&apos; SubClassOf &apos;has primary input&apos; some &apos;ion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060250</classIRI>
<classLabel>germ-line stem-cell niche homeostasis</classLabel>
<newAxiom>&apos;germ-line stem-cell niche homeostasis&apos; SubClassOf not (&apos;in taxon&apos; some &apos;Fungi&apos;)</newAxiom>
<newAxiom>&apos;germ-line stem-cell niche homeostasis&apos; DisjointWith &apos;in taxon&apos; some &apos;Fungi&apos;</newAxiom>
<newAxiom>&apos;germ-line stem-cell niche homeostasis&apos; SubClassOf &apos;in taxon&apos; some (not (&apos;Fungi&apos;))</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050801</classIRI>
<classLabel>ion homeostasis</classLabel>
<deletedAxiom>&apos;ion homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;ion&apos;</deletedAxiom>
<deletedAxiom>&apos;ion homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;ion&apos;)</deletedAxiom>
<newAxiom>&apos;ion homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;monoatomic ion&apos;)</newAxiom>
<newAxiom>&apos;ion homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;monoatomic ion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050803</classIRI>
<classLabel>regulation of synapse structure or activity</classLabel>
<newAxiom>&apos;regulation of synapse structure or activity&apos; SubClassOf &apos;in taxon&apos; only &apos;Eumetazoa&apos;</newAxiom>
<newAxiom>&apos;regulation of synapse structure or activity&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eumetazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050865</classIRI>
<classLabel>regulation of cell activation</classLabel>
<newAxiom>&apos;regulation of cell activation&apos; SubClassOf &apos;regulation of multicellular organismal process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050866</classIRI>
<classLabel>negative regulation of cell activation</classLabel>
<newAxiom>&apos;negative regulation of cell activation&apos; SubClassOf &apos;negative regulation of multicellular organismal process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050867</classIRI>
<classLabel>positive regulation of cell activation</classLabel>
<newAxiom>&apos;positive regulation of cell activation&apos; SubClassOf &apos;positive regulation of multicellular organismal process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098838</classIRI>
<classLabel>folate transmembrane transport</classLabel>
<deletedAxiom>&apos;folate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098768</classIRI>
<classLabel>meiotic prometaphase I</classLabel>
<newAxiom>&apos;meiotic prometaphase I&apos; SubClassOf &apos;meiotic M phase&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098771</classIRI>
<classLabel>inorganic ion homeostasis</classLabel>
<deletedAxiom>&apos;inorganic ion homeostasis&apos; SubClassOf &apos;ion homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;inorganic ion homeostasis&apos; SubClassOf &apos;chemical homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905010</classIRI>
<classLabel>positive regulation of L-lysine import across plasma membrane</classLabel>
<deletedAxiom>&apos;positive regulation of L-lysine import across plasma membrane&apos; SubClassOf &apos;positive regulation of cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of L-lysine import across plasma membrane&apos; SubClassOf &apos;positive regulation of anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of L-lysine import across plasma membrane&apos; SubClassOf &apos;positive regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905009</classIRI>
<classLabel>negative regulation of L-lysine import across plasma membrane</classLabel>
<deletedAxiom>&apos;negative regulation of L-lysine import across plasma membrane&apos; SubClassOf &apos;negative regulation of anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of L-lysine import across plasma membrane&apos; SubClassOf &apos;negative regulation of cation transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of L-lysine import across plasma membrane&apos; SubClassOf &apos;negative regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905008</classIRI>
<classLabel>regulation of L-lysine import across plasma membrane</classLabel>
<deletedAxiom>&apos;regulation of L-lysine import across plasma membrane&apos; SubClassOf &apos;regulation of cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of L-lysine import across plasma membrane&apos; SubClassOf &apos;regulation of anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098718</classIRI>
<classLabel>serine import across plasma membrane</classLabel>
<deletedAxiom>&apos;serine import across plasma membrane&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;serine import across plasma membrane&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098655</classIRI>
<classLabel>cation transmembrane transport</classLabel>
<deletedAxiom>&apos;cation transmembrane transport&apos; EquivalentTo &apos;transport&apos; and (&apos;results in transport across&apos; some &apos;membrane&apos;) and (&apos;has primary input&apos; some &apos;cation&apos;)</deletedAxiom>
<newAxiom>&apos;cation transmembrane transport&apos; EquivalentTo &apos;transport&apos; and (&apos;results in transport across&apos; some &apos;membrane&apos;) and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098656</classIRI>
<classLabel>anion transmembrane transport</classLabel>
<deletedAxiom>&apos;anion transmembrane transport&apos; EquivalentTo &apos;transport&apos; and (&apos;results in transport across&apos; some &apos;membrane&apos;) and (&apos;has primary input&apos; some &apos;anion&apos;)</deletedAxiom>
<newAxiom>&apos;anion transmembrane transport&apos; EquivalentTo &apos;transport&apos; and (&apos;results in transport across&apos; some &apos;membrane&apos;) and (&apos;has primary input&apos; some &apos;monoatomic anion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098660</classIRI>
<classLabel>inorganic ion transmembrane transport</classLabel>
<deletedAxiom>&apos;inorganic ion transmembrane transport&apos; SubClassOf &apos;ion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;inorganic ion transmembrane transport&apos; SubClassOf &apos;transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098661</classIRI>
<classLabel>inorganic anion transmembrane transport</classLabel>
<deletedAxiom>&apos;inorganic anion transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098662</classIRI>
<classLabel>inorganic cation transmembrane transport</classLabel>
<deletedAxiom>&apos;inorganic cation transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001775</classIRI>
<classLabel>cell activation</classLabel>
<newAxiom>&apos;cell activation&apos; SubClassOf &apos;multicellular organismal process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001776</classIRI>
<classLabel>leukocyte homeostasis</classLabel>
<newAxiom>&apos;leukocyte homeostasis&apos; SubClassOf &apos;in taxon&apos; only &apos;Vertebrata vertebrates&apos;</newAxiom>
<newAxiom>&apos;leukocyte homeostasis&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Vertebrata vertebrates&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905135</classIRI>
<classLabel>biotin import across plasma membrane</classLabel>
<deletedAxiom>&apos;biotin import across plasma membrane&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905136</classIRI>
<classLabel>dethiobiotin import across plasma membrane</classLabel>
<deletedAxiom>&apos;dethiobiotin import across plasma membrane&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001680</classIRI>
<classLabel>tRNA 3&apos;-terminal CCA addition</classLabel>
<newAxiom>&apos;tRNA 3&apos;-terminal CCA addition&apos; SubClassOf &apos;has_part&apos; some &apos;CCA tRNA nucleotidyltransferase&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905409</classIRI>
<classLabel>positive regulation of creatine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;positive regulation of creatine transmembrane transporter activity&apos; SubClassOf &apos;positive regulation of ion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of creatine transmembrane transporter activity&apos; SubClassOf &apos;positive regulation of transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905407</classIRI>
<classLabel>regulation of creatine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;regulation of creatine transmembrane transporter activity&apos; SubClassOf &apos;regulation of ion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;regulation of creatine transmembrane transporter activity&apos; SubClassOf &apos;regulation of transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905408</classIRI>
<classLabel>negative regulation of creatine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;negative regulation of creatine transmembrane transporter activity&apos; SubClassOf &apos;negative regulation of ion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of creatine transmembrane transporter activity&apos; SubClassOf &apos;negative regulation of transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001407</classIRI>
<classLabel>glycerophosphodiester transmembrane transport</classLabel>
<deletedAxiom>&apos;glycerophosphodiester transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;glycerophosphodiester transmembrane transport&apos; SubClassOf &apos;transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015904</classIRI>
<classLabel>tetracycline transmembrane transport</classLabel>
<deletedAxiom>&apos;tetracycline transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;tetracycline transmembrane transport&apos; SubClassOf &apos;transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905541</classIRI>
<classLabel>regulation of L-arginine import across plasma membrane</classLabel>
<deletedAxiom>&apos;regulation of L-arginine import across plasma membrane&apos; SubClassOf &apos;regulation of cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of L-arginine import across plasma membrane&apos; SubClassOf &apos;regulation of anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905542</classIRI>
<classLabel>negative regulation of L-arginine import across plasma membrane</classLabel>
<deletedAxiom>&apos;negative regulation of L-arginine import across plasma membrane&apos; SubClassOf &apos;negative regulation of cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of L-arginine import across plasma membrane&apos; SubClassOf &apos;negative regulation of anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of L-arginine import across plasma membrane&apos; SubClassOf &apos;negative regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905589</classIRI>
<classLabel>positive regulation of L-arginine import across plasma membrane</classLabel>
<deletedAxiom>&apos;positive regulation of L-arginine import across plasma membrane&apos; SubClassOf &apos;positive regulation of cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of L-arginine import across plasma membrane&apos; SubClassOf &apos;positive regulation of anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of L-arginine import across plasma membrane&apos; SubClassOf &apos;positive regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015810</classIRI>
<classLabel>aspartate transmembrane transport</classLabel>
<deletedAxiom>&apos;aspartate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015819</classIRI>
<classLabel>lysine transport</classLabel>
<deletedAxiom>&apos;lysine transport&apos; SubClassOf &apos;has primary input&apos; some &apos;lysinium(1+)&apos;</deletedAxiom>
<deletedAxiom>&apos;lysine transport&apos; SubClassOf &apos;carboxylic acid transport&apos;</deletedAxiom>
<deletedAxiom>&apos;lysine transport&apos; SubClassOf &apos;cation transport&apos;</deletedAxiom>
<deletedAxiom>&apos;lysine transport&apos; EquivalentTo &apos;basic amino acid transport&apos; and (&apos;has primary input&apos; some &apos;lysinium(1+)&apos;)</deletedAxiom>
<newAxiom>&apos;lysine transport&apos; SubClassOf &apos;L-lysine transport&apos;</newAxiom>
<newAxiom>&apos;lysine transport&apos; EquivalentTo &apos;basic amino acid transport&apos; and (&apos;has primary input&apos; some &apos;L-lysinium(1+)&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015816</classIRI>
<classLabel>glycine transport</classLabel>
<deletedAxiom>&apos;glycine transport&apos; SubClassOf &apos;cation transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015813</classIRI>
<classLabel>L-glutamate transmembrane transport</classLabel>
<deletedAxiom>&apos;L-glutamate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015822</classIRI>
<classLabel>ornithine transport</classLabel>
<deletedAxiom>&apos;ornithine transport&apos; SubClassOf &apos;cation transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015821</classIRI>
<classLabel>methionine transport</classLabel>
<deletedAxiom>&apos;methionine transport&apos; SubClassOf &apos;cation transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015827</classIRI>
<classLabel>tryptophan transport</classLabel>
<deletedAxiom>&apos;tryptophan transport&apos; SubClassOf &apos;cation transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015843</classIRI>
<classLabel>methylammonium transport</classLabel>
<deletedAxiom>&apos;methylammonium transport&apos; SubClassOf &apos;cation transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015872</classIRI>
<classLabel>dopamine transport</classLabel>
<deletedAxiom>&apos;dopamine transport&apos; SubClassOf &apos;cation transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015887</classIRI>
<classLabel>pantothenate transmembrane transport</classLabel>
<deletedAxiom>&apos;pantothenate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015882</classIRI>
<classLabel>L-ascorbic acid transmembrane transport</classLabel>
<deletedAxiom>&apos;L-ascorbic acid transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015881</classIRI>
<classLabel>creatine transmembrane transport</classLabel>
<deletedAxiom>&apos;creatine transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;creatine transmembrane transport&apos; SubClassOf &apos;transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905625</classIRI>
<classLabel>negative regulation of L-methionine import across plasma membrane</classLabel>
<deletedAxiom>&apos;negative regulation of L-methionine import across plasma membrane&apos; SubClassOf &apos;negative regulation of anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of L-methionine import across plasma membrane&apos; SubClassOf &apos;negative regulation of cation transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of L-methionine import across plasma membrane&apos; SubClassOf &apos;negative regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905626</classIRI>
<classLabel>positive regulation of L-methionine import across plasma membrane</classLabel>
<deletedAxiom>&apos;positive regulation of L-methionine import across plasma membrane&apos; SubClassOf &apos;positive regulation of cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of L-methionine import across plasma membrane&apos; SubClassOf &apos;positive regulation of anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of L-methionine import across plasma membrane&apos; SubClassOf &apos;positive regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905624</classIRI>
<classLabel>regulation of L-methionine import across plasma membrane</classLabel>
<deletedAxiom>&apos;regulation of L-methionine import across plasma membrane&apos; SubClassOf &apos;regulation of cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of L-methionine import across plasma membrane&apos; SubClassOf &apos;regulation of anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050184</classIRI>
<classLabel>phosphatidylcholine desaturase activity</classLabel>
<deletedAxiom>&apos;phosphatidylcholine desaturase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;oleoyl-containing glycerolipid&apos;</deletedAxiom>
<deletedAxiom>&apos;phosphatidylcholine desaturase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</deletedAxiom>
<deletedAxiom>&apos;phosphatidylcholine desaturase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;iron(2+)&apos;</deletedAxiom>
<deletedAxiom>&apos;phosphatidylcholine desaturase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;iron(3+)&apos;</deletedAxiom>
<deletedAxiom>&apos;phosphatidylcholine desaturase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;linoleoyl-containing glycerolipid&apos;</deletedAxiom>
<deletedAxiom>&apos;phosphatidylcholine desaturase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;water&apos;</deletedAxiom>
<deletedAxiom>&apos;phosphatidylcholine desaturase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;dioxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015705</classIRI>
<classLabel>iodide transport</classLabel>
<newAxiom>&apos;iodide transport&apos; SubClassOf &apos;anion transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015704</classIRI>
<classLabel>cyanate transport</classLabel>
<deletedAxiom>&apos;cyanate transport&apos; SubClassOf &apos;anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015711</classIRI>
<classLabel>organic anion transport</classLabel>
<deletedAxiom>&apos;organic anion transport&apos; SubClassOf &apos;anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015735</classIRI>
<classLabel>uronic acid transmembrane transport</classLabel>
<deletedAxiom>&apos;uronic acid transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;uronic acid transmembrane transport&apos; SubClassOf &apos;transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015733</classIRI>
<classLabel>shikimate transmembrane transport</classLabel>
<deletedAxiom>&apos;shikimate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015789</classIRI>
<classLabel>UDP-N-acetylgalactosamine transmembrane transport</classLabel>
<deletedAxiom>&apos;UDP-N-acetylgalactosamine transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015787</classIRI>
<classLabel>UDP-glucuronic acid transmembrane transport</classLabel>
<deletedAxiom>&apos;UDP-glucuronic acid transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015786</classIRI>
<classLabel>UDP-glucose transmembrane transport</classLabel>
<deletedAxiom>&apos;UDP-glucose transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015782</classIRI>
<classLabel>CMP-N-acetylneuraminate transmembrane transport</classLabel>
<deletedAxiom>&apos;CMP-N-acetylneuraminate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015794</classIRI>
<classLabel>glycerol-3-phosphate transmembrane transport</classLabel>
<deletedAxiom>&apos;glycerol-3-phosphate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;glycerol-3-phosphate transmembrane transport&apos; SubClassOf &apos;transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015790</classIRI>
<classLabel>UDP-xylose transmembrane transport</classLabel>
<deletedAxiom>&apos;UDP-xylose transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039693</classIRI>
<classLabel>viral DNA genome replication</classLabel>
<newAxiom>&apos;viral DNA genome replication&apos; SubClassOf &apos;DNA biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039694</classIRI>
<classLabel>viral RNA genome replication</classLabel>
<newAxiom>&apos;viral RNA genome replication&apos; SubClassOf &apos;RNA biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904448</classIRI>
<classLabel>regulation of aspartate secretion</classLabel>
<deletedAxiom>&apos;regulation of aspartate secretion&apos; SubClassOf &apos;regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904449</classIRI>
<classLabel>negative regulation of aspartate secretion</classLabel>
<deletedAxiom>&apos;negative regulation of aspartate secretion&apos; SubClassOf &apos;negative regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904450</classIRI>
<classLabel>positive regulation of aspartate secretion</classLabel>
<deletedAxiom>&apos;positive regulation of aspartate secretion&apos; SubClassOf &apos;positive regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015624</classIRI>
<classLabel>ABC-type ferric-enterobactin transporter activity</classLabel>
<deletedAxiom>&apos;ABC-type ferric-enterobactin transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015662</classIRI>
<classLabel>P-type ion transporter activity</classLabel>
<deletedAxiom>&apos;P-type ion transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;P-type ion transporter activity&apos; SubClassOf &apos;has primary input&apos; some &apos;ion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015698</classIRI>
<classLabel>inorganic anion transport</classLabel>
<deletedAxiom>&apos;inorganic anion transport&apos; SubClassOf &apos;anion transport&apos;</deletedAxiom>
<newAxiom>&apos;inorganic anion transport&apos; SubClassOf &apos;transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015695</classIRI>
<classLabel>organic cation transport</classLabel>
<deletedAxiom>&apos;organic cation transport&apos; SubClassOf &apos;cation transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015694</classIRI>
<classLabel>mercury ion transport</classLabel>
<newAxiom>&apos;mercury ion transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015599</classIRI>
<classLabel>ATPase-coupled L-glutamine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;ATPase-coupled L-glutamine transmembrane transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015594</classIRI>
<classLabel>ABC-type putrescine transporter activity</classLabel>
<deletedAxiom>&apos;ABC-type putrescine transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904555</classIRI>
<classLabel>L-proline transmembrane transport</classLabel>
<deletedAxiom>&apos;L-proline transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;L-proline transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904556</classIRI>
<classLabel>L-tryptophan transmembrane transport</classLabel>
<deletedAxiom>&apos;L-tryptophan transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;L-tryptophan transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904557</classIRI>
<classLabel>L-alanine transmembrane transport</classLabel>
<deletedAxiom>&apos;L-alanine transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;L-alanine transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015505</classIRI>
<classLabel>uracil:cation symporter activity</classLabel>
<deletedAxiom>&apos;uracil:cation symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;uracil&apos;) and (&apos;has primary input&apos; some &apos;inorganic cation&apos;)</deletedAxiom>
<newAxiom>&apos;uracil:cation symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;uracil&apos;) and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015514</classIRI>
<classLabel>nitrite efflux transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;nitrite efflux transmembrane transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015515</classIRI>
<classLabel>citrate:succinate antiporter activity</classLabel>
<deletedAxiom>&apos;citrate:succinate antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;citrate:succinate antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015513</classIRI>
<classLabel>high-affinity secondary active nitrite transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;high-affinity secondary active nitrite transmembrane transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015516</classIRI>
<classLabel>tartrate:succinate antiporter activity</classLabel>
<deletedAxiom>&apos;tartrate:succinate antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;tartrate:succinate antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;tartrate:succinate antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015520</classIRI>
<classLabel>tetracycline:proton antiporter activity</classLabel>
<deletedAxiom>&apos;tetracycline:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;tetracycline:proton antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;tetracycline zwitterion&apos;)</deletedAxiom>
<deletedAxiom>&apos;tetracycline:proton antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;tetracycline:proton antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;tetracycline:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;tetracycline:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;tetracycline zwitterion&apos;)</newAxiom>
<newAxiom>&apos;tetracycline:proton antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015539</classIRI>
<classLabel>hexuronate:cation symporter activity</classLabel>
<deletedAxiom>&apos;hexuronate:cation symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;hexuronate&apos;) and (&apos;has primary input&apos; some &apos;inorganic cation&apos;)</deletedAxiom>
<newAxiom>&apos;hexuronate:cation symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;) and (&apos;has primary input&apos; some &apos;hexuronate&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015544</classIRI>
<classLabel>phenyl propionate uniporter activity</classLabel>
<deletedAxiom>&apos;phenyl propionate uniporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015541</classIRI>
<classLabel>secondary active cyanate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;secondary active cyanate transmembrane transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015558</classIRI>
<classLabel>secondary active p-aminobenzoyl-glutamate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;secondary active p-aminobenzoyl-glutamate transmembrane transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904624</classIRI>
<classLabel>regulation of glycine secretion, neurotransmission</classLabel>
<deletedAxiom>&apos;regulation of glycine secretion, neurotransmission&apos; SubClassOf &apos;regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904625</classIRI>
<classLabel>negative regulation of glycine secretion, neurotransmission</classLabel>
<deletedAxiom>&apos;negative regulation of glycine secretion, neurotransmission&apos; SubClassOf &apos;negative regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015487</classIRI>
<classLabel>melibiose:cation symporter activity</classLabel>
<deletedAxiom>&apos;melibiose:cation symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;melibiose&apos;) and (&apos;has primary input&apos; some &apos;inorganic cation&apos;)</deletedAxiom>
<newAxiom>&apos;melibiose:cation symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;) and (&apos;has primary input&apos; some &apos;melibiose&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904626</classIRI>
<classLabel>positive regulation of glycine secretion, neurotransmission</classLabel>
<deletedAxiom>&apos;positive regulation of glycine secretion, neurotransmission&apos; SubClassOf &apos;positive regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015496</classIRI>
<classLabel>putrescine:ornithine antiporter activity</classLabel>
<deletedAxiom>&apos;putrescine:ornithine antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;putrescine:ornithine antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;putrescine:ornithine antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015400</classIRI>
<classLabel>low-affinity secondary active ammonium transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;low-affinity secondary active ammonium transmembrane transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015411</classIRI>
<classLabel>ABC-type taurine transporter transporter activity</classLabel>
<deletedAxiom>&apos;ABC-type taurine transporter transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015418</classIRI>
<classLabel>ABC-type quaternary ammonium compound transporting activity</classLabel>
<deletedAxiom>&apos;ABC-type quaternary ammonium compound transporting activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015436</classIRI>
<classLabel>ABC-type capsular-polysaccharide transporter activity</classLabel>
<deletedAxiom>&apos;ABC-type capsular-polysaccharide transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015430</classIRI>
<classLabel>ABC-type glycerol-3-phosphate transporter activity</classLabel>
<deletedAxiom>&apos;ABC-type glycerol-3-phosphate transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015446</classIRI>
<classLabel>ATPase-coupled arsenite transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;ATPase-coupled arsenite transmembrane transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030974</classIRI>
<classLabel>thiamine pyrophosphate transmembrane transport</classLabel>
<deletedAxiom>&apos;thiamine pyrophosphate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015347</classIRI>
<classLabel>sodium-independent organic anion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;sodium-independent organic anion transmembrane transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015351</classIRI>
<classLabel>bilirubin secondary active transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;bilirubin secondary active transmembrane transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015369</classIRI>
<classLabel>calcium:proton antiporter activity</classLabel>
<deletedAxiom>&apos;calcium:proton antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;calcium(2+)&apos;)</deletedAxiom>
<newAxiom>&apos;calcium:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;calcium(2+)&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015367</classIRI>
<classLabel>oxoglutarate:malate antiporter activity</classLabel>
<deletedAxiom>&apos;oxoglutarate:malate antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;oxoglutarate:malate antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;oxoglutarate:malate antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015368</classIRI>
<classLabel>calcium:cation antiporter activity</classLabel>
<deletedAxiom>&apos;calcium:cation antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;calcium(2+)&apos;) and (&apos;has primary input&apos; some &apos;cation&apos;)</deletedAxiom>
<newAxiom>&apos;calcium:cation antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;) and (&apos;has primary input&apos; some &apos;calcium(2+)&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015377</classIRI>
<classLabel>cation:chloride symporter activity</classLabel>
<deletedAxiom>&apos;cation:chloride symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;chloride&apos;) and (&apos;has primary input&apos; some &apos;inorganic cation&apos;)</deletedAxiom>
<newAxiom>&apos;cation:chloride symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;chloride&apos;) and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015373</classIRI>
<classLabel>anion:sodium symporter activity</classLabel>
<deletedAxiom>&apos;anion:sodium symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;inorganic anion&apos;) and (&apos;has primary input&apos; some &apos;sodium(1+)&apos;)</deletedAxiom>
<newAxiom>&apos;anion:sodium symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic anion&apos;) and (&apos;has primary input&apos; some &apos;sodium(1+)&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015385</classIRI>
<classLabel>sodium:proton antiporter activity</classLabel>
<deletedAxiom>&apos;sodium:proton antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;sodium(1+)&apos;)</deletedAxiom>
<newAxiom>&apos;sodium:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;sodium(1+)&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015386</classIRI>
<classLabel>potassium:proton antiporter activity</classLabel>
<deletedAxiom>&apos;potassium:proton antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;potassium(1+)&apos;)</deletedAxiom>
<newAxiom>&apos;potassium:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;potassium(1+)&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015383</classIRI>
<classLabel>sulfate:bicarbonate antiporter activity</classLabel>
<deletedAxiom>&apos;sulfate:bicarbonate antiporter activity&apos; SubClassOf &apos;bicarbonate:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;sulfate:bicarbonate antiporter activity&apos; SubClassOf &apos;bicarbonate transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015382</classIRI>
<classLabel>sodium:sulfate symporter activity</classLabel>
<deletedAxiom>&apos;sodium:sulfate symporter activity&apos; SubClassOf &apos;anion:sodium symporter activity&apos;</deletedAxiom>
<newAxiom>&apos;sodium:sulfate symporter activity&apos; SubClassOf &apos;solute:sodium symporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015398</classIRI>
<classLabel>high-affinity secondary active ammonium transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;high-affinity secondary active ammonium transmembrane transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015391</classIRI>
<classLabel>nucleobase:cation symporter activity</classLabel>
<deletedAxiom>&apos;nucleobase:cation symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;nucleobase&apos;) and (&apos;has primary input&apos; some &apos;inorganic cation&apos;)</deletedAxiom>
<newAxiom>&apos;nucleobase:cation symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;nucleobase&apos;) and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904782</classIRI>
<classLabel>negative regulation of NMDA glutamate receptor activity</classLabel>
<deletedAxiom>&apos;negative regulation of NMDA glutamate receptor activity&apos; SubClassOf &apos;negative regulation of cation channel activity&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of NMDA glutamate receptor activity&apos; SubClassOf &apos;negative regulation of ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904783</classIRI>
<classLabel>positive regulation of NMDA glutamate receptor activity</classLabel>
<deletedAxiom>&apos;positive regulation of NMDA glutamate receptor activity&apos; SubClassOf &apos;positive regulation of cation channel activity&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of NMDA glutamate receptor activity&apos; SubClassOf &apos;positive regulation of ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904919</classIRI>
<classLabel>transmembrane L-cystine transport from lysosomal lumen to cytosol</classLabel>
<deletedAxiom>&apos;transmembrane L-cystine transport from lysosomal lumen to cytosol&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015306</classIRI>
<classLabel>sialate:cation symporter activity</classLabel>
<deletedAxiom>&apos;sialate:cation symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;N-acetylneuraminate&apos;) and (&apos;has primary input&apos; some &apos;inorganic cation&apos;)</deletedAxiom>
<newAxiom>&apos;sialate:cation symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;) and (&apos;has primary input&apos; some &apos;N-acetylneuraminate&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015309</classIRI>
<classLabel>cycloheximide:proton antiporter activity</classLabel>
<deletedAxiom>&apos;cycloheximide:proton antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;cycloheximide&apos;)</deletedAxiom>
<deletedAxiom>&apos;cycloheximide:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;cycloheximide:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;cycloheximide&apos;)</newAxiom>
<newAxiom>&apos;cycloheximide:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;cycloheximide:proton antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;cycloheximide:proton antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015308</classIRI>
<classLabel>amiloride:proton antiporter activity</classLabel>
<deletedAxiom>&apos;amiloride:proton antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;amiloride&apos;)</deletedAxiom>
<deletedAxiom>&apos;amiloride:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;amiloride:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;amiloride:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;amiloride&apos;)</newAxiom>
<newAxiom>&apos;amiloride:proton antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;amiloride:proton antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015314</classIRI>
<classLabel>aminotriazole:proton antiporter activity</classLabel>
<deletedAxiom>&apos;aminotriazole:proton antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;amitrole&apos;)</deletedAxiom>
<newAxiom>&apos;aminotriazole:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;amitrole&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015312</classIRI>
<classLabel>polyamine:proton antiporter activity</classLabel>
<deletedAxiom>&apos;polyamine:proton antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;polyamine macromolecule&apos;)</deletedAxiom>
<deletedAxiom>&apos;polyamine:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;polyamine:proton antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
<newAxiom>&apos;polyamine:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;polyamine:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;polyamine macromolecule&apos;)</newAxiom>
<newAxiom>&apos;polyamine:proton antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015313</classIRI>
<classLabel>fluconazole:proton antiporter activity</classLabel>
<deletedAxiom>&apos;fluconazole:proton antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;fluconazole&apos;)</deletedAxiom>
<newAxiom>&apos;fluconazole:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;fluconazole&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015310</classIRI>
<classLabel>benomyl:proton antiporter activity</classLabel>
<deletedAxiom>&apos;benomyl:proton antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;benomyl&apos;)</deletedAxiom>
<deletedAxiom>&apos;benomyl:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;benomyl:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;benomyl:proton antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;benomyl:proton antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
<newAxiom>&apos;benomyl:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;benomyl&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015311</classIRI>
<classLabel>monoamine:proton antiporter activity</classLabel>
<deletedAxiom>&apos;monoamine:proton antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;monoamine&apos;)</deletedAxiom>
<deletedAxiom>&apos;monoamine:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;monoamine:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;monoamine&apos;)</newAxiom>
<newAxiom>&apos;monoamine:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;monoamine:proton antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
<newAxiom>&apos;monoamine:proton antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015327</classIRI>
<classLabel>cystine:glutamate antiporter activity</classLabel>
<deletedAxiom>&apos;cystine:glutamate antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;cystine:glutamate antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;cystine:glutamate antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015325</classIRI>
<classLabel>acetyl-CoA:CoA antiporter activity</classLabel>
<deletedAxiom>&apos;acetyl-CoA:CoA antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;acetyl-CoA:CoA antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;acetyl-CoA:CoA antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015276</classIRI>
<classLabel>ligand-gated ion channel activity</classLabel>
<deletedAxiom>&apos;ligand-gated ion channel activity&apos; SubClassOf &apos;ion channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;ligand-gated ion channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;has primary input&apos; some &apos;inorganic ion&apos;)</deletedAxiom>
<newAxiom>&apos;ligand-gated ion channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic ion&apos;)</newAxiom>
<newAxiom>&apos;ligand-gated ion channel activity&apos; SubClassOf &apos;ion gated channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015299</classIRI>
<classLabel>solute:proton antiporter activity</classLabel>
<deletedAxiom>&apos;solute:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;solute:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;chemical entity&apos;) and (&apos;has primary input&apos; some &apos;proton&apos;)</deletedAxiom>
<deletedAxiom>&apos;solute:proton antiporter activity&apos; SubClassOf &apos;monovalent cation:proton antiporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015298</classIRI>
<classLabel>solute:cation antiporter activity</classLabel>
<deletedAxiom>&apos;solute:cation antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;solute:cation antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;solute:cation antiporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;solute:cation antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;chemical entity&apos;) and (&apos;has primary input&apos; some &apos;cation&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015296</classIRI>
<classLabel>anion:cation symporter activity</classLabel>
<deletedAxiom>&apos;anion:cation symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;inorganic anion&apos;) and (&apos;has primary input&apos; some &apos;inorganic cation&apos;)</deletedAxiom>
<deletedAxiom>&apos;anion:cation symporter activity&apos; SubClassOf &apos;inorganic anion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;anion:cation symporter activity&apos; SubClassOf &apos;anion transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;anion:cation symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic anion&apos;) and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015294</classIRI>
<classLabel>solute:cation symporter activity</classLabel>
<deletedAxiom>&apos;solute:cation symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;chemical entity&apos;) and (&apos;has primary input&apos; some &apos;inorganic cation&apos;)</deletedAxiom>
<deletedAxiom>&apos;solute:cation symporter activity&apos; SubClassOf &apos;inorganic cation transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;solute:cation symporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;solute:cation symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;) and (&apos;has primary input&apos; some &apos;chemical entity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015200</classIRI>
<classLabel>methylammonium transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;methylammonium transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005883</classIRI>
<classLabel>neurofilament</classLabel>
<newAxiom>&apos;neurofilament&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eumetazoa&apos;</newAxiom>
<newAxiom>&apos;neurofilament&apos; SubClassOf &apos;in taxon&apos; only &apos;Eumetazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015108</classIRI>
<classLabel>chloride transmembrane transporter activity</classLabel>
<newAxiom>&apos;chloride transmembrane transporter activity&apos; SubClassOf &apos;anion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015103</classIRI>
<classLabel>inorganic anion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;inorganic anion transmembrane transporter activity&apos; SubClassOf &apos;anion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015101</classIRI>
<classLabel>organic cation transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;organic cation transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;organic cation transmembrane transporter activity&apos; SubClassOf &apos;transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015110</classIRI>
<classLabel>cyanate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;cyanate transmembrane transporter activity&apos; SubClassOf &apos;anion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;cyanate transmembrane transporter activity&apos; SubClassOf &apos;transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015111</classIRI>
<classLabel>iodide transmembrane transporter activity</classLabel>
<newAxiom>&apos;iodide transmembrane transporter activity&apos; SubClassOf &apos;anion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904983</classIRI>
<classLabel>glycine import into mitochondrion</classLabel>
<deletedAxiom>&apos;glycine import into mitochondrion&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;glycine import into mitochondrion&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015189</classIRI>
<classLabel>L-lysine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;L-lysine transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015187</classIRI>
<classLabel>glycine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;glycine transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015188</classIRI>
<classLabel>L-isoleucine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;L-isoleucine transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015186</classIRI>
<classLabel>L-glutamine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;L-glutamine transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015182</classIRI>
<classLabel>L-asparagine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;L-asparagine transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015190</classIRI>
<classLabel>L-leucine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;L-leucine transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015196</classIRI>
<classLabel>L-tryptophan transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;L-tryptophan transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015195</classIRI>
<classLabel>L-threonine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;L-threonine transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015192</classIRI>
<classLabel>L-phenylalanine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;L-phenylalanine transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015193</classIRI>
<classLabel>L-proline transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;L-proline transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030641</classIRI>
<classLabel>regulation of cellular pH</classLabel>
<deletedAxiom>&apos;regulation of cellular pH&apos; SubClassOf &apos;cellular monovalent inorganic cation homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;regulation of cellular pH&apos; SubClassOf &apos;cellular cation homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030642</classIRI>
<classLabel>cellular sulfate ion homeostasis</classLabel>
<deletedAxiom>&apos;cellular sulfate ion homeostasis&apos; SubClassOf &apos;cellular divalent inorganic anion homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;cellular sulfate ion homeostasis&apos; SubClassOf &apos;cellular chemical homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030643</classIRI>
<classLabel>cellular phosphate ion homeostasis</classLabel>
<deletedAxiom>&apos;cellular phosphate ion homeostasis&apos; SubClassOf &apos;cellular trivalent inorganic anion homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;cellular phosphate ion homeostasis&apos; SubClassOf &apos;cellular chemical homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030644</classIRI>
<classLabel>cellular chloride ion homeostasis</classLabel>
<deletedAxiom>&apos;cellular chloride ion homeostasis&apos; SubClassOf &apos;cellular monovalent inorganic anion homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;cellular chloride ion homeostasis&apos; SubClassOf &apos;cellular anion homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030645</classIRI>
<classLabel>glucose catabolic process to butyrate</classLabel>
<deletedAxiom>&apos;glucose catabolic process to butyrate&apos; SubClassOf &apos;hexose catabolic process to butyrate&apos;</deletedAxiom>
<newAxiom>&apos;glucose catabolic process to butyrate&apos; SubClassOf &apos;butyrate metabolic process&apos;</newAxiom>
<newAxiom>&apos;glucose catabolic process to butyrate&apos; SubClassOf &apos;has primary output&apos; some &apos;butyrate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015078</classIRI>
<classLabel>proton transmembrane transporter activity</classLabel>
<newAxiom>&apos;proton transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015075</classIRI>
<classLabel>ion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;ion transmembrane transporter activity&apos; EquivalentTo &apos;transmembrane transporter activity&apos; and (&apos;has primary input&apos; some &apos;ion&apos;)</deletedAxiom>
<deletedAxiom>&apos;ion transmembrane transporter activity&apos; SubClassOf &apos;has primary input&apos; some &apos;ion&apos;</deletedAxiom>
<newAxiom>&apos;ion transmembrane transporter activity&apos; SubClassOf &apos;has primary input&apos; some &apos;monoatomic ion&apos;</newAxiom>
<newAxiom>&apos;ion transmembrane transporter activity&apos; EquivalentTo &apos;transmembrane transporter activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic ion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015083</classIRI>
<classLabel>aluminum ion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;aluminum ion transmembrane transporter activity&apos; SubClassOf &apos;ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015094</classIRI>
<classLabel>lead ion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;lead ion transmembrane transporter activity&apos; SubClassOf &apos;ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900024</classIRI>
<classLabel>regulation of substrate adhesion-dependent cell spreading</classLabel>
<deletedAxiom>&apos;regulation of substrate adhesion-dependent cell spreading&apos; SubClassOf &apos;regulation of cell morphogenesis involved in differentiation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900025</classIRI>
<classLabel>negative regulation of substrate adhesion-dependent cell spreading</classLabel>
<deletedAxiom>&apos;negative regulation of substrate adhesion-dependent cell spreading&apos; SubClassOf &apos;negative regulation of cell morphogenesis involved in differentiation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900026</classIRI>
<classLabel>positive regulation of substrate adhesion-dependent cell spreading</classLabel>
<deletedAxiom>&apos;positive regulation of substrate adhesion-dependent cell spreading&apos; SubClassOf &apos;positive regulation of cell morphogenesis involved in differentiation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005451</classIRI>
<classLabel>monovalent cation:proton antiporter activity</classLabel>
<deletedAxiom>&apos;monovalent cation:proton antiporter activity&apos; SubClassOf &apos;has input&apos; some &apos;proton&apos;</deletedAxiom>
<deletedAxiom>&apos;monovalent cation:proton antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;monovalent cation:proton antiporter activity&apos; SubClassOf &apos;inorganic cation transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;monovalent cation:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;monovalent inorganic cation&apos;)</deletedAxiom>
<deletedAxiom>&apos;monovalent cation:proton antiporter activity&apos; SubClassOf &apos;has primary input&apos; some &apos;monovalent inorganic cation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005452</classIRI>
<classLabel>solute:inorganic anion antiporter activity</classLabel>
<deletedAxiom>&apos;solute:inorganic anion antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;solute:inorganic anion antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;solute:inorganic anion antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005469</classIRI>
<classLabel>succinate:fumarate antiporter activity</classLabel>
<deletedAxiom>&apos;succinate:fumarate antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;succinate:fumarate antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;succinate:fumarate antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005471</classIRI>
<classLabel>ATP:ADP antiporter activity</classLabel>
<deletedAxiom>&apos;ATP:ADP antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;ATP:ADP antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;ATP:ADP antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005476</classIRI>
<classLabel>carnitine:acyl carnitine antiporter activity</classLabel>
<deletedAxiom>&apos;carnitine:acyl carnitine antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;carnitine:acyl carnitine antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005477</classIRI>
<classLabel>pyruvate secondary active transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;pyruvate secondary active transmembrane transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030435</classIRI>
<classLabel>sporulation resulting in formation of a cellular spore</classLabel>
<deletedAxiom>&apos;sporulation resulting in formation of a cellular spore&apos; SubClassOf &apos;cell differentiation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030437</classIRI>
<classLabel>ascospore formation</classLabel>
<newAxiom>&apos;ascospore formation&apos; SubClassOf &apos;meiotic cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900071</classIRI>
<classLabel>regulation of sulfite transport</classLabel>
<deletedAxiom>&apos;regulation of sulfite transport&apos; SubClassOf &apos;regulation of anion transport&apos;</deletedAxiom>
<newAxiom>&apos;regulation of sulfite transport&apos; SubClassOf &apos;regulation of transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900072</classIRI>
<classLabel>positive regulation of sulfite transport</classLabel>
<deletedAxiom>&apos;positive regulation of sulfite transport&apos; SubClassOf &apos;positive regulation of anion transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of sulfite transport&apos; SubClassOf &apos;positive regulation of transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005402</classIRI>
<classLabel>carbohydrate:cation symporter activity</classLabel>
<deletedAxiom>&apos;carbohydrate:cation symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;carbohydrate&apos;) and (&apos;has primary input&apos; some &apos;inorganic cation&apos;)</deletedAxiom>
<newAxiom>&apos;carbohydrate:cation symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;carbohydrate&apos;) and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005416</classIRI>
<classLabel>amino acid:cation symporter activity</classLabel>
<deletedAxiom>&apos;amino acid:cation symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;amino acid&apos;) and (&apos;has primary input&apos; some &apos;inorganic cation&apos;)</deletedAxiom>
<newAxiom>&apos;amino acid:cation symporter activity&apos; EquivalentTo &apos;symporter activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;) and (&apos;has primary input&apos; some &apos;amino acid&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005302</classIRI>
<classLabel>L-tyrosine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;L-tyrosine transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005304</classIRI>
<classLabel>L-valine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;L-valine transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030320</classIRI>
<classLabel>cellular monovalent inorganic anion homeostasis</classLabel>
<deletedAxiom>&apos;cellular monovalent inorganic anion homeostasis&apos; SubClassOf &apos;cellular anion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular monovalent inorganic anion homeostasis&apos; EquivalentTo &apos;cellular homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;monovalent inorganic anion&apos;)</deletedAxiom>
<deletedAxiom>&apos;cellular monovalent inorganic anion homeostasis&apos; SubClassOf &apos;monovalent inorganic anion homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005371</classIRI>
<classLabel>tricarboxylate secondary active transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;tricarboxylate secondary active transmembrane transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019829</classIRI>
<classLabel>ATPase-coupled cation transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;ATPase-coupled cation transmembrane transporter activity&apos; SubClassOf &apos;inorganic cation transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;ATPase-coupled cation transmembrane transporter activity&apos; EquivalentTo &apos;ATPase-coupled transmembrane transporter activity&apos; and (&apos;has primary input&apos; some &apos;inorganic cation&apos;)</deletedAxiom>
<newAxiom>&apos;ATPase-coupled cation transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;ATPase-coupled cation transmembrane transporter activity&apos; EquivalentTo &apos;ATPase-coupled transmembrane transporter activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005216</classIRI>
<classLabel>ion channel activity</classLabel>
<deletedAxiom>&apos;ion channel activity&apos; SubClassOf &apos;has primary input&apos; some &apos;inorganic ion&apos;</deletedAxiom>
<deletedAxiom>&apos;ion channel activity&apos; EquivalentTo &apos;channel activity&apos; and (&apos;has primary input&apos; some &apos;inorganic ion&apos;)</deletedAxiom>
<deletedAxiom>&apos;ion channel activity&apos; SubClassOf &apos;inorganic molecular entity transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;ion channel activity&apos; EquivalentTo &apos;channel activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic ion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005227</classIRI>
<classLabel>calcium activated cation channel activity</classLabel>
<deletedAxiom>&apos;calcium activated cation channel activity&apos; SubClassOf &apos;cation channel activity&apos;</deletedAxiom>
<newAxiom>&apos;calcium activated cation channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;regulated by&apos; some &apos;calcium(2+)&apos;) and (&apos;has primary input&apos; some &apos;monoatomic ion&apos;)</newAxiom>
<newAxiom>&apos;calcium activated cation channel activity&apos; SubClassOf &apos;regulated by&apos; some &apos;calcium(2+)&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005229</classIRI>
<classLabel>intracellular calcium activated chloride channel activity</classLabel>
<deletedAxiom>&apos;intracellular calcium activated chloride channel activity&apos; SubClassOf &apos;ion gated channel activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005244</classIRI>
<classLabel>voltage-gated ion channel activity</classLabel>
<deletedAxiom>&apos;voltage-gated ion channel activity&apos; SubClassOf &apos;ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;voltage-gated ion channel activity&apos; EquivalentTo &apos;voltage-gated channel activity&apos; and (&apos;has primary input&apos; some &apos;ion&apos;)</deletedAxiom>
<newAxiom>&apos;voltage-gated ion channel activity&apos; SubClassOf &apos;ion gated channel activity&apos;</newAxiom>
<newAxiom>&apos;voltage-gated ion channel activity&apos; EquivalentTo &apos;voltage-gated channel activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic ion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005253</classIRI>
<classLabel>anion channel activity</classLabel>
<deletedAxiom>&apos;anion channel activity&apos; EquivalentTo &apos;channel activity&apos; and (&apos;has primary input&apos; some &apos;inorganic anion&apos;)</deletedAxiom>
<deletedAxiom>&apos;anion channel activity&apos; SubClassOf &apos;inorganic anion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;anion channel activity&apos; EquivalentTo &apos;channel activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic anion&apos;)</newAxiom>
<newAxiom>&apos;anion channel activity&apos; SubClassOf &apos;anion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005261</classIRI>
<classLabel>cation channel activity</classLabel>
<deletedAxiom>&apos;cation channel activity&apos; EquivalentTo &apos;channel activity&apos; and (&apos;has primary input&apos; some &apos;inorganic cation&apos;)</deletedAxiom>
<deletedAxiom>&apos;cation channel activity&apos; SubClassOf &apos;inorganic cation transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;cation channel activity&apos; EquivalentTo &apos;channel activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</newAxiom>
<newAxiom>&apos;cation channel activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005278</classIRI>
<classLabel>acetylcholine:proton antiporter activity</classLabel>
<deletedAxiom>&apos;acetylcholine:proton antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;acetylcholine&apos;) and (&apos;has primary input&apos; some &apos;proton&apos;)</deletedAxiom>
<deletedAxiom>&apos;acetylcholine:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;acetylcholine:proton antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
<newAxiom>&apos;acetylcholine:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;acetylcholine&apos;) and (&apos;has primary input&apos; some &apos;proton&apos;)</newAxiom>
<newAxiom>&apos;acetylcholine:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;acetylcholine:proton antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005290</classIRI>
<classLabel>L-histidine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;L-histidine transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019812</classIRI>
<classLabel>type I site-specific deoxyribonuclease complex</classLabel>
<newAxiom>&apos;type I site-specific deoxyribonuclease complex&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Prokaryota&apos;</newAxiom>
<newAxiom>&apos;type I site-specific deoxyribonuclease complex&apos; SubClassOf &apos;in taxon&apos; only &apos;Prokaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019813</classIRI>
<classLabel>type III site-specific deoxyribonuclease complex</classLabel>
<newAxiom>&apos;type III site-specific deoxyribonuclease complex&apos; SubClassOf &apos;in taxon&apos; only &apos;Prokaryota&apos;</newAxiom>
<newAxiom>&apos;type III site-specific deoxyribonuclease complex&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Prokaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019656</classIRI>
<classLabel>glucose catabolic process to D-lactate and ethanol</classLabel>
<deletedAxiom>&apos;glucose catabolic process to D-lactate and ethanol&apos; SubClassOf &apos;hexose catabolic process to ethanol&apos;</deletedAxiom>
<newAxiom>&apos;glucose catabolic process to D-lactate and ethanol&apos; SubClassOf &apos;has primary output&apos; some &apos;ethanol&apos;</newAxiom>
<newAxiom>&apos;glucose catabolic process to D-lactate and ethanol&apos; SubClassOf &apos;ethanol metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030002</classIRI>
<classLabel>cellular anion homeostasis</classLabel>
<deletedAxiom>&apos;cellular anion homeostasis&apos; EquivalentTo &apos;cellular homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;anion&apos;)</deletedAxiom>
<newAxiom>&apos;cellular anion homeostasis&apos; EquivalentTo &apos;cellular homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;monoatomic anion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030003</classIRI>
<classLabel>cellular cation homeostasis</classLabel>
<deletedAxiom>&apos;cellular cation homeostasis&apos; EquivalentTo &apos;cellular homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;cation&apos;)</deletedAxiom>
<newAxiom>&apos;cellular cation homeostasis&apos; EquivalentTo &apos;cellular homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;monoatomic cation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030004</classIRI>
<classLabel>cellular monovalent inorganic cation homeostasis</classLabel>
<deletedAxiom>&apos;cellular monovalent inorganic cation homeostasis&apos; SubClassOf &apos;monovalent inorganic cation homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular monovalent inorganic cation homeostasis&apos; EquivalentTo &apos;cellular homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;monovalent inorganic cation&apos;)</deletedAxiom>
<deletedAxiom>&apos;cellular monovalent inorganic cation homeostasis&apos; SubClassOf &apos;cellular cation homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030007</classIRI>
<classLabel>cellular potassium ion homeostasis</classLabel>
<deletedAxiom>&apos;cellular potassium ion homeostasis&apos; SubClassOf &apos;cellular monovalent inorganic cation homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044667</classIRI>
<classLabel>(R)-carnitine:4-(trimethylammonio)butanoate antiporter activity</classLabel>
<deletedAxiom>&apos;(R)-carnitine:4-(trimethylammonio)butanoate antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;(R)-carnitine:4-(trimethylammonio)butanoate antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010960</classIRI>
<classLabel>magnesium ion homeostasis</classLabel>
<deletedAxiom>&apos;magnesium ion homeostasis&apos; SubClassOf &apos;divalent inorganic cation homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010961</classIRI>
<classLabel>cellular magnesium ion homeostasis</classLabel>
<deletedAxiom>&apos;cellular magnesium ion homeostasis&apos; SubClassOf &apos;cellular divalent inorganic cation homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010966</classIRI>
<classLabel>regulation of phosphate transport</classLabel>
<deletedAxiom>&apos;regulation of phosphate transport&apos; SubClassOf &apos;regulation of anion transport&apos;</deletedAxiom>
<newAxiom>&apos;regulation of phosphate transport&apos; SubClassOf &apos;regulation of transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046873</classIRI>
<classLabel>metal ion transmembrane transporter activity</classLabel>
<newAxiom>&apos;metal ion transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071887</classIRI>
<classLabel>leukocyte apoptotic process</classLabel>
<newAxiom>&apos;leukocyte apoptotic process&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Vertebrata vertebrates&apos;</newAxiom>
<newAxiom>&apos;leukocyte apoptotic process&apos; SubClassOf &apos;in taxon&apos; only &apos;Vertebrata vertebrates&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032281</classIRI>
<classLabel>AMPA glutamate receptor complex</classLabel>
<deletedAxiom>&apos;AMPA glutamate receptor complex&apos; SubClassOf &apos;cation channel complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140021</classIRI>
<classLabel>mitochondrial ADP transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial ADP transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022839</classIRI>
<classLabel>ion gated channel activity</classLabel>
<newAxiom>&apos;ion gated channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic ion&apos;)</newAxiom>
<newAxiom>&apos;ion gated channel activity&apos; SubClassOf &apos;ion channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022850</classIRI>
<classLabel>serotonin-gated cation-selective channel activity</classLabel>
<deletedAxiom>&apos;serotonin-gated cation-selective channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;regulated by&apos; some &apos;serotonin binding&apos;) and (&apos;has primary input&apos; some &apos;inorganic cation&apos;)</deletedAxiom>
<newAxiom>&apos;serotonin-gated cation-selective channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;regulated by&apos; some &apos;serotonin binding&apos;) and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022843</classIRI>
<classLabel>voltage-gated cation channel activity</classLabel>
<deletedAxiom>&apos;voltage-gated cation channel activity&apos; EquivalentTo &apos;voltage-gated channel activity&apos; and (&apos;has primary input&apos; some &apos;inorganic cation&apos;)</deletedAxiom>
<newAxiom>&apos;voltage-gated cation channel activity&apos; EquivalentTo &apos;voltage-gated channel activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022848</classIRI>
<classLabel>acetylcholine-gated cation-selective channel activity</classLabel>
<deletedAxiom>&apos;acetylcholine-gated cation-selective channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;regulated by&apos; some &apos;acetylcholine binding&apos;) and (&apos;has primary input&apos; some &apos;inorganic cation&apos;)</deletedAxiom>
<newAxiom>&apos;acetylcholine-gated cation-selective channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;regulated by&apos; some &apos;acetylcholine binding&apos;) and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022853</classIRI>
<classLabel>active ion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;active ion transmembrane transporter activity&apos; EquivalentTo &apos;active transmembrane transporter activity&apos; and (&apos;has primary input&apos; some &apos;ion&apos;)</deletedAxiom>
<newAxiom>&apos;active ion transmembrane transporter activity&apos; EquivalentTo &apos;active transmembrane transporter activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic ion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022858</classIRI>
<classLabel>alanine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;alanine transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071805</classIRI>
<classLabel>potassium ion transmembrane transport</classLabel>
<newAxiom>&apos;potassium ion transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022890</classIRI>
<classLabel>inorganic cation transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;inorganic cation transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022889</classIRI>
<classLabel>serine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;serine transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032111</classIRI>
<classLabel>activation of protein histidine kinase activity</classLabel>
<deletedAxiom>&apos;activation of protein histidine kinase activity&apos; SubClassOf &apos;activation of protein kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;activation of protein histidine kinase activity&apos; SubClassOf &apos;positive regulation of protein histidine kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046715</classIRI>
<classLabel>active borate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;active borate transmembrane transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;active borate transmembrane transporter activity&apos; SubClassOf &apos;active transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007159</classIRI>
<classLabel>leukocyte cell-cell adhesion</classLabel>
<deletedAxiom>&apos;leukocyte cell-cell adhesion&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Metazoa&apos;</deletedAxiom>
<newAxiom>&apos;leukocyte cell-cell adhesion&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Vertebrata vertebrates&apos;</newAxiom>
<newAxiom>&apos;leukocyte cell-cell adhesion&apos; SubClassOf &apos;in taxon&apos; only &apos;Vertebrata vertebrates&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007062</classIRI>
<classLabel>sister chromatid cohesion</classLabel>
<deletedAxiom>&apos;sister chromatid cohesion&apos; SubClassOf &apos;part of&apos; some &apos;sister chromatid segregation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032068</classIRI>
<classLabel>type IV site-specific deoxyribonuclease complex</classLabel>
<newAxiom>&apos;type IV site-specific deoxyribonuclease complex&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Prokaryota&apos;</newAxiom>
<newAxiom>&apos;type IV site-specific deoxyribonuclease complex&apos; SubClassOf &apos;in taxon&apos; only &apos;Prokaryota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022620</classIRI>
<classLabel>vegetative cell differentiation</classLabel>
<newAxiom>&apos;vegetative cell differentiation&apos; SubClassOf &apos;in taxon&apos; only &apos;Spermatophyta&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071577</classIRI>
<classLabel>zinc ion transmembrane transport</classLabel>
<newAxiom>&apos;zinc ion transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046411</classIRI>
<classLabel>2-keto-3-deoxygluconate transmembrane transport</classLabel>
<deletedAxiom>&apos;2-keto-3-deoxygluconate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071421</classIRI>
<classLabel>manganese ion transmembrane transport</classLabel>
<newAxiom>&apos;manganese ion transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071423</classIRI>
<classLabel>malate transmembrane transport</classLabel>
<deletedAxiom>&apos;malate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071422</classIRI>
<classLabel>succinate transmembrane transport</classLabel>
<deletedAxiom>&apos;succinate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061907</classIRI>
<classLabel>negative regulation of AMPA receptor activity</classLabel>
<deletedAxiom>&apos;negative regulation of AMPA receptor activity&apos; SubClassOf &apos;negative regulation of cation channel activity&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of AMPA receptor activity&apos; SubClassOf &apos;negative regulation of ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071142</classIRI>
<classLabel>homomeric SMAD protein complex</classLabel>
<newAxiom>&apos;homomeric SMAD protein complex&apos; SubClassOf &apos;in taxon&apos; only &apos;Eumetazoa&apos;</newAxiom>
<newAxiom>&apos;homomeric SMAD protein complex&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eumetazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061732</classIRI>
<classLabel>mitochondrial acetyl-CoA biosynthetic process from pyruvate</classLabel>
<deletedAxiom>&apos;mitochondrial acetyl-CoA biosynthetic process from pyruvate&apos; SubClassOf &apos;starts with&apos; some &apos;mitochondrial pyruvate transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;mitochondrial acetyl-CoA biosynthetic process from pyruvate&apos; SubClassOf &apos;ends with&apos; some &apos;pyruvate dehydrogenase [NAD(P)+] activity&apos;</deletedAxiom>
<deletedAxiom>&apos;mitochondrial acetyl-CoA biosynthetic process from pyruvate&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;starts with&apos; some &apos;mitochondrial pyruvate transmembrane transport&apos;) and (&apos;ends with&apos; some &apos;pyruvate dehydrogenase [NAD(P)+] activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;mitochondrial acetyl-CoA biosynthetic process from pyruvate&apos; SubClassOf &apos;acetyl-CoA biosynthetic process from pyruvate&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061797</classIRI>
<classLabel>pH-gated chloride channel activity</classLabel>
<deletedAxiom>&apos;pH-gated chloride channel activity&apos; SubClassOf &apos;gated channel activity&apos;</deletedAxiom>
<newAxiom>&apos;pH-gated chloride channel activity&apos; SubClassOf &apos;ion gated channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061545</classIRI>
<classLabel>tyramine secretion</classLabel>
<deletedAxiom>&apos;tyramine secretion&apos; SubClassOf &apos;cation transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061459</classIRI>
<classLabel>L-arginine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;L-arginine transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036457</classIRI>
<classLabel>keratohyalin granule</classLabel>
<newAxiom>&apos;keratohyalin granule&apos; SubClassOf &apos;in taxon&apos; only &apos;Eumetazoa&apos;</newAxiom>
<newAxiom>&apos;keratohyalin granule&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eumetazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061436</classIRI>
<classLabel>establishment of skin barrier</classLabel>
<deletedAxiom>&apos;establishment of skin barrier&apos; SubClassOf &apos;regulation of water loss via skin&apos;</deletedAxiom>
<deletedAxiom>&apos;establishment of skin barrier&apos; SubClassOf &apos;part of&apos; some &apos;skin development&apos;</deletedAxiom>
<newAxiom>&apos;establishment of skin barrier&apos; SubClassOf &apos;skin epidermis development&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120189</classIRI>
<classLabel>positive regulation of bile acid secretion</classLabel>
<deletedAxiom>&apos;positive regulation of bile acid secretion&apos; SubClassOf &apos;positive regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120188</classIRI>
<classLabel>regulation of bile acid secretion</classLabel>
<deletedAxiom>&apos;regulation of bile acid secretion&apos; SubClassOf &apos;regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120190</classIRI>
<classLabel>negative regulation of bile acid secretion</classLabel>
<deletedAxiom>&apos;negative regulation of bile acid secretion&apos; SubClassOf &apos;negative regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051950</classIRI>
<classLabel>positive regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse</classLabel>
<deletedAxiom>&apos;positive regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse&apos; SubClassOf &apos;positive regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051949</classIRI>
<classLabel>negative regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse</classLabel>
<deletedAxiom>&apos;negative regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse&apos; SubClassOf &apos;negative regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051947</classIRI>
<classLabel>regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse</classLabel>
<deletedAxiom>&apos;regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse&apos; SubClassOf &apos;regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120099</classIRI>
<classLabel>procentriole replication complex</classLabel>
<newAxiom>&apos;procentriole replication complex&apos; SubClassOf &apos;in taxon&apos; only &apos;Eumetazoa&apos;</newAxiom>
<newAxiom>&apos;procentriole replication complex&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eumetazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120098</classIRI>
<classLabel>procentriole</classLabel>
<newAxiom>&apos;procentriole&apos; SubClassOf &apos;in taxon&apos; only &apos;Eumetazoa&apos;</newAxiom>
<newAxiom>&apos;procentriole&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eumetazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036249</classIRI>
<classLabel>cadmium ion import into vacuole</classLabel>
<newAxiom>&apos;cadmium ion import into vacuole&apos; SubClassOf &apos;cation transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051608</classIRI>
<classLabel>histamine transport</classLabel>
<deletedAxiom>&apos;histamine transport&apos; SubClassOf &apos;cation transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051633</classIRI>
<classLabel>positive regulation of acetylcholine uptake</classLabel>
<deletedAxiom>&apos;positive regulation of acetylcholine uptake&apos; SubClassOf &apos;positive regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051632</classIRI>
<classLabel>negative regulation of acetylcholine uptake</classLabel>
<deletedAxiom>&apos;negative regulation of acetylcholine uptake&apos; SubClassOf &apos;negative regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051631</classIRI>
<classLabel>regulation of acetylcholine uptake</classLabel>
<deletedAxiom>&apos;regulation of acetylcholine uptake&apos; SubClassOf &apos;regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051612</classIRI>
<classLabel>negative regulation of serotonin uptake</classLabel>
<deletedAxiom>&apos;negative regulation of serotonin uptake&apos; SubClassOf &apos;negative regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051611</classIRI>
<classLabel>regulation of serotonin uptake</classLabel>
<deletedAxiom>&apos;regulation of serotonin uptake&apos; SubClassOf &apos;regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051613</classIRI>
<classLabel>positive regulation of serotonin uptake</classLabel>
<deletedAxiom>&apos;positive regulation of serotonin uptake&apos; SubClassOf &apos;positive regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051616</classIRI>
<classLabel>regulation of histamine uptake</classLabel>
<deletedAxiom>&apos;regulation of histamine uptake&apos; SubClassOf &apos;regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051618</classIRI>
<classLabel>positive regulation of histamine uptake</classLabel>
<deletedAxiom>&apos;positive regulation of histamine uptake&apos; SubClassOf &apos;positive regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051617</classIRI>
<classLabel>negative regulation of histamine uptake</classLabel>
<deletedAxiom>&apos;negative regulation of histamine uptake&apos; SubClassOf &apos;negative regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051623</classIRI>
<classLabel>positive regulation of norepinephrine uptake</classLabel>
<deletedAxiom>&apos;positive regulation of norepinephrine uptake&apos; SubClassOf &apos;positive regulation of ion transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of norepinephrine uptake&apos; SubClassOf &apos;positive regulation of transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051622</classIRI>
<classLabel>negative regulation of norepinephrine uptake</classLabel>
<deletedAxiom>&apos;negative regulation of norepinephrine uptake&apos; SubClassOf &apos;negative regulation of ion transport&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of norepinephrine uptake&apos; SubClassOf &apos;negative regulation of transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051621</classIRI>
<classLabel>regulation of norepinephrine uptake</classLabel>
<deletedAxiom>&apos;regulation of norepinephrine uptake&apos; SubClassOf &apos;regulation of ion transport&apos;</deletedAxiom>
<newAxiom>&apos;regulation of norepinephrine uptake&apos; SubClassOf &apos;regulation of transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904200</classIRI>
<classLabel>iodide transmembrane transport</classLabel>
<newAxiom>&apos;iodide transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904212</classIRI>
<classLabel>regulation of iodide transmembrane transport</classLabel>
<newAxiom>&apos;regulation of iodide transmembrane transport&apos; SubClassOf &apos;regulation of anion transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904214</classIRI>
<classLabel>positive regulation of iodide transmembrane transport</classLabel>
<newAxiom>&apos;positive regulation of iodide transmembrane transport&apos; SubClassOf &apos;positive regulation of anion transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904213</classIRI>
<classLabel>negative regulation of iodide transmembrane transport</classLabel>
<newAxiom>&apos;negative regulation of iodide transmembrane transport&apos; SubClassOf &apos;negative regulation of anion transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051584</classIRI>
<classLabel>regulation of dopamine uptake involved in synaptic transmission</classLabel>
<deletedAxiom>&apos;regulation of dopamine uptake involved in synaptic transmission&apos; SubClassOf &apos;regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051586</classIRI>
<classLabel>positive regulation of dopamine uptake involved in synaptic transmission</classLabel>
<deletedAxiom>&apos;positive regulation of dopamine uptake involved in synaptic transmission&apos; SubClassOf &apos;positive regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051585</classIRI>
<classLabel>negative regulation of dopamine uptake involved in synaptic transmission</classLabel>
<deletedAxiom>&apos;negative regulation of dopamine uptake involved in synaptic transmission&apos; SubClassOf &apos;negative regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904360</classIRI>
<classLabel>negative regulation of spore germination</classLabel>
<deletedAxiom>&apos;negative regulation of spore germination&apos; SubClassOf &apos;negative regulation of cell differentiation&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of spore germination&apos; SubClassOf &apos;negative regulation of developmental process&apos;</newAxiom>
<newAxiom>&apos;negative regulation of spore germination&apos; SubClassOf &apos;negative regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904361</classIRI>
<classLabel>positive regulation of spore germination</classLabel>
<deletedAxiom>&apos;positive regulation of spore germination&apos; SubClassOf &apos;positive regulation of cell differentiation&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of spore germination&apos; SubClassOf &apos;positive regulation of cellular process&apos;</newAxiom>
<newAxiom>&apos;positive regulation of spore germination&apos; SubClassOf &apos;positive regulation of developmental process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904359</classIRI>
<classLabel>regulation of spore germination</classLabel>
<deletedAxiom>&apos;regulation of spore germination&apos; SubClassOf &apos;regulation of cell differentiation&apos;</deletedAxiom>
<newAxiom>&apos;regulation of spore germination&apos; SubClassOf &apos;regulation of cellular process&apos;</newAxiom>
<newAxiom>&apos;regulation of spore germination&apos; SubClassOf &apos;regulation of developmental process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903118</classIRI>
<classLabel>urate homeostasis</classLabel>
<deletedAxiom>&apos;urate homeostasis&apos; SubClassOf &apos;chemical homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;urate homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;urate salt&apos;</deletedAxiom>
<deletedAxiom>&apos;urate homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;urate salt&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051225</classIRI>
<classLabel>spindle assembly</classLabel>
<newAxiom>&apos;spindle assembly&apos; SubClassOf &apos;part of&apos; some &apos;chromosome segregation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903222</classIRI>
<classLabel>quinolinic acid transmembrane transport</classLabel>
<deletedAxiom>&apos;quinolinic acid transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075296</classIRI>
<classLabel>positive regulation of ascospore formation</classLabel>
<newAxiom>&apos;positive regulation of ascospore formation&apos; SubClassOf &apos;positive regulation of cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075297</classIRI>
<classLabel>negative regulation of ascospore formation</classLabel>
<newAxiom>&apos;negative regulation of ascospore formation&apos; SubClassOf &apos;negative regulation of cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110067</classIRI>
<classLabel>ammonium transmembrane transporter complex</classLabel>
<deletedAxiom>&apos;ammonium transmembrane transporter complex&apos; SubClassOf &apos;cation channel complex&apos;</deletedAxiom>
<newAxiom>&apos;ammonium transmembrane transporter complex&apos; SubClassOf &apos;transmembrane transporter complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903401</classIRI>
<classLabel>L-lysine transmembrane transport</classLabel>
<deletedAxiom>&apos;L-lysine transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;L-lysine transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903352</classIRI>
<classLabel>L-ornithine transmembrane transport</classLabel>
<deletedAxiom>&apos;L-ornithine transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;L-ornithine transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0089722</classIRI>
<classLabel>phosphoenolpyruvate transmembrane transport</classLabel>
<deletedAxiom>&apos;phosphoenolpyruvate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0089709</classIRI>
<classLabel>L-histidine transmembrane transport</classLabel>
<deletedAxiom>&apos;L-histidine transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;L-histidine transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099100</classIRI>
<classLabel>G-protein gated cation channel activity</classLabel>
<deletedAxiom>&apos;G-protein gated cation channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;regulated by&apos; some &apos;G-protein beta/gamma-subunit complex binding&apos;) and (&apos;has primary input&apos; some &apos;inorganic cation&apos;)</deletedAxiom>
<newAxiom>&apos;G-protein gated cation channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;regulated by&apos; some &apos;G-protein beta/gamma-subunit complex binding&apos;) and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051139</classIRI>
<classLabel>metal cation:proton antiporter activity</classLabel>
<deletedAxiom>&apos;metal cation:proton antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;metal cation&apos;)</deletedAxiom>
<deletedAxiom>&apos;metal cation:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;metal cation:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;metal cation&apos;)</newAxiom>
<newAxiom>&apos;metal cation:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099094</classIRI>
<classLabel>ligand-gated cation channel activity</classLabel>
<deletedAxiom>&apos;ligand-gated cation channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;has primary input&apos; some &apos;inorganic cation&apos;)</deletedAxiom>
<newAxiom>&apos;ligand-gated cation channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099095</classIRI>
<classLabel>ligand-gated anion channel activity</classLabel>
<deletedAxiom>&apos;ligand-gated anion channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;has primary input&apos; some &apos;inorganic anion&apos;)</deletedAxiom>
<newAxiom>&apos;ligand-gated anion channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic anion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090686</classIRI>
<classLabel>glycine betaine-activated nonselective monovalent cation channel activity</classLabel>
<newAxiom>&apos;glycine betaine-activated nonselective monovalent cation channel activity&apos; SubClassOf &apos;amino-acid betaine transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;glycine betaine-activated nonselective monovalent cation channel activity&apos; EquivalentTo &apos;ligand-gated ion channel activity&apos; and (&apos;has primary input&apos; some &apos;glycine betaine&apos;) and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099099</classIRI>
<classLabel>G-protein gated ion channel activity</classLabel>
<deletedAxiom>&apos;G-protein gated ion channel activity&apos; SubClassOf &apos;ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;G-protein gated ion channel activity&apos; SubClassOf &apos;gated channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;G-protein gated ion channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;regulated by&apos; some &apos;G-protein beta/gamma-subunit complex binding&apos;) and (&apos;has primary input&apos; some &apos;ion&apos;)</deletedAxiom>
<newAxiom>&apos;G-protein gated ion channel activity&apos; SubClassOf &apos;ion gated channel activity&apos;</newAxiom>
<newAxiom>&apos;G-protein gated ion channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;regulated by&apos; some &apos;G-protein beta/gamma-subunit complex binding&apos;) and (&apos;has primary input&apos; some &apos;monoatomic ion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002038</classIRI>
<classLabel>positive regulation of L-glutamate import across plasma membrane</classLabel>
<deletedAxiom>&apos;positive regulation of L-glutamate import across plasma membrane&apos; SubClassOf &apos;positive regulation of anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of L-glutamate import across plasma membrane&apos; SubClassOf &apos;positive regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002037</classIRI>
<classLabel>negative regulation of L-glutamate import across plasma membrane</classLabel>
<deletedAxiom>&apos;negative regulation of L-glutamate import across plasma membrane&apos; SubClassOf &apos;negative regulation of anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of L-glutamate import across plasma membrane&apos; SubClassOf &apos;negative regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002036</classIRI>
<classLabel>regulation of L-glutamate import across plasma membrane</classLabel>
<deletedAxiom>&apos;regulation of L-glutamate import across plasma membrane&apos; SubClassOf &apos;regulation of anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903424</classIRI>
<classLabel>fluoride transmembrane transport</classLabel>
<newAxiom>&apos;fluoride transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903425</classIRI>
<classLabel>fluoride transmembrane transporter activity</classLabel>
<newAxiom>&apos;fluoride transmembrane transporter activity&apos; SubClassOf &apos;anion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903594</classIRI>
<classLabel>negative regulation of histamine secretion by mast cell</classLabel>
<deletedAxiom>&apos;negative regulation of histamine secretion by mast cell&apos; SubClassOf &apos;negative regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903593</classIRI>
<classLabel>regulation of histamine secretion by mast cell</classLabel>
<deletedAxiom>&apos;regulation of histamine secretion by mast cell&apos; SubClassOf &apos;regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903595</classIRI>
<classLabel>positive regulation of histamine secretion by mast cell</classLabel>
<deletedAxiom>&apos;positive regulation of histamine secretion by mast cell&apos; SubClassOf &apos;positive regulation of multicellular organismal process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histamine secretion by mast cell&apos; SubClassOf &apos;positive regulation of ion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090516</classIRI>
<classLabel>L-serine transmembrane import into vacuole</classLabel>
<deletedAxiom>&apos;L-serine transmembrane import into vacuole&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;L-serine transmembrane import into vacuole&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090514</classIRI>
<classLabel>L-tyrosine transmembrane import into vacuole</classLabel>
<deletedAxiom>&apos;L-tyrosine transmembrane import into vacuole&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;L-tyrosine transmembrane import into vacuole&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090463</classIRI>
<classLabel>cellular lysine homeostasis</classLabel>
<deletedAxiom>&apos;cellular lysine homeostasis&apos; SubClassOf &apos;cellular anion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular lysine homeostasis&apos; SubClassOf &apos;cellular cation homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090465</classIRI>
<classLabel>cellular arginine homeostasis</classLabel>
<deletedAxiom>&apos;cellular arginine homeostasis&apos; SubClassOf &apos;cellular cation homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular arginine homeostasis&apos; SubClassOf &apos;cellular anion homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090462</classIRI>
<classLabel>cellular ornithine homeostasis</classLabel>
<deletedAxiom>&apos;cellular ornithine homeostasis&apos; SubClassOf &apos;cellular anion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular ornithine homeostasis&apos; SubClassOf &apos;cellular cation homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090461</classIRI>
<classLabel>cellular glutamate homeostasis</classLabel>
<deletedAxiom>&apos;cellular glutamate homeostasis&apos; SubClassOf &apos;cellular anion homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090459</classIRI>
<classLabel>cellular aspartate homeostasis</classLabel>
<deletedAxiom>&apos;cellular aspartate homeostasis&apos; SubClassOf &apos;cellular anion homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090452</classIRI>
<classLabel>lithium ion transmembrane transport</classLabel>
<newAxiom>&apos;lithium ion transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090455</classIRI>
<classLabel>ornithine transmembrane import into vacuole</classLabel>
<deletedAxiom>&apos;ornithine transmembrane import into vacuole&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;ornithine transmembrane import into vacuole&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090454</classIRI>
<classLabel>glutamate transmembrane import into vacuole</classLabel>
<deletedAxiom>&apos;glutamate transmembrane import into vacuole&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090448</classIRI>
<classLabel>glucosinolate:proton symporter activity</classLabel>
<deletedAxiom>&apos;glucosinolate:proton symporter activity&apos; SubClassOf &apos;anion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903710</classIRI>
<classLabel>spermine transmembrane transport</classLabel>
<deletedAxiom>&apos;spermine transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903712</classIRI>
<classLabel>cysteine transmembrane transport</classLabel>
<deletedAxiom>&apos;cysteine transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;cysteine transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903711</classIRI>
<classLabel>spermidine transmembrane transport</classLabel>
<deletedAxiom>&apos;spermidine transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016469</classIRI>
<classLabel>proton-transporting two-sector ATPase complex</classLabel>
<newAxiom>&apos;proton-transporting two-sector ATPase complex&apos; SubClassOf &apos;ATPase complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903692</classIRI>
<classLabel>methionine import across plasma membrane</classLabel>
<deletedAxiom>&apos;methionine import across plasma membrane&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;methionine import across plasma membrane&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903801</classIRI>
<classLabel>L-leucine import across plasma membrane</classLabel>
<deletedAxiom>&apos;L-leucine import across plasma membrane&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;L-leucine import across plasma membrane&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903804</classIRI>
<classLabel>glycine import across plasma membrane</classLabel>
<deletedAxiom>&apos;glycine import across plasma membrane&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;glycine import across plasma membrane&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903803</classIRI>
<classLabel>L-glutamine import across plasma membrane</classLabel>
<deletedAxiom>&apos;L-glutamine import across plasma membrane&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;L-glutamine import across plasma membrane&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903806</classIRI>
<classLabel>L-isoleucine import across plasma membrane</classLabel>
<deletedAxiom>&apos;L-isoleucine import across plasma membrane&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;L-isoleucine import across plasma membrane&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903808</classIRI>
<classLabel>L-tyrosine import across plasma membrane</classLabel>
<deletedAxiom>&apos;L-tyrosine import across plasma membrane&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;L-tyrosine import across plasma membrane&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903807</classIRI>
<classLabel>L-threonine import across plasma membrane</classLabel>
<deletedAxiom>&apos;L-threonine import across plasma membrane&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;L-threonine import across plasma membrane&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903830</classIRI>
<classLabel>magnesium ion transmembrane transport</classLabel>
<newAxiom>&apos;magnesium ion transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903811</classIRI>
<classLabel>L-asparagine import across plasma membrane</classLabel>
<deletedAxiom>&apos;L-asparagine import across plasma membrane&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;L-asparagine import across plasma membrane&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903826</classIRI>
<classLabel>L-arginine transmembrane transport</classLabel>
<deletedAxiom>&apos;L-arginine transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;L-arginine transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903796</classIRI>
<classLabel>negative regulation of inorganic anion transmembrane transport</classLabel>
<deletedAxiom>&apos;negative regulation of inorganic anion transmembrane transport&apos; SubClassOf &apos;negative regulation of anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of inorganic anion transmembrane transport&apos; SubClassOf &apos;negative regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903795</classIRI>
<classLabel>regulation of inorganic anion transmembrane transport</classLabel>
<deletedAxiom>&apos;regulation of inorganic anion transmembrane transport&apos; SubClassOf &apos;regulation of anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;regulation of inorganic anion transmembrane transport&apos; SubClassOf &apos;regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903797</classIRI>
<classLabel>positive regulation of inorganic anion transmembrane transport</classLabel>
<deletedAxiom>&apos;positive regulation of inorganic anion transmembrane transport&apos; SubClassOf &apos;positive regulation of anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of inorganic anion transmembrane transport&apos; SubClassOf &apos;positive regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903785</classIRI>
<classLabel>L-valine transmembrane transport</classLabel>
<deletedAxiom>&apos;L-valine transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;L-valine transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090307</classIRI>
<classLabel>mitotic spindle assembly</classLabel>
<deletedAxiom>&apos;mitotic spindle assembly&apos; SubClassOf &apos;part of&apos; some &apos;mitotic nuclear division&apos;</deletedAxiom>
<newAxiom>&apos;mitotic spindle assembly&apos; SubClassOf &apos;part of&apos; some &apos;mitotic sister chromatid segregation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090306</classIRI>
<classLabel>meiotic spindle assembly</classLabel>
<deletedAxiom>&apos;meiotic spindle assembly&apos; SubClassOf &apos;part of&apos; some &apos;meiotic nuclear division&apos;</deletedAxiom>
<newAxiom>&apos;meiotic spindle assembly&apos; SubClassOf &apos;part of&apos; some &apos;meiotic chromosome segregation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006874</classIRI>
<classLabel>cellular calcium ion homeostasis</classLabel>
<deletedAxiom>&apos;cellular calcium ion homeostasis&apos; SubClassOf &apos;cellular divalent inorganic cation homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006873</classIRI>
<classLabel>cellular ion homeostasis</classLabel>
<deletedAxiom>&apos;cellular ion homeostasis&apos; EquivalentTo &apos;cellular homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;ion&apos;)</deletedAxiom>
<newAxiom>&apos;cellular ion homeostasis&apos; EquivalentTo &apos;cellular homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;monoatomic ion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006876</classIRI>
<classLabel>cellular cadmium ion homeostasis</classLabel>
<deletedAxiom>&apos;cellular cadmium ion homeostasis&apos; SubClassOf &apos;cellular divalent inorganic cation homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006883</classIRI>
<classLabel>cellular sodium ion homeostasis</classLabel>
<deletedAxiom>&apos;cellular sodium ion homeostasis&apos; SubClassOf &apos;cellular monovalent inorganic cation homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006882</classIRI>
<classLabel>cellular zinc ion homeostasis</classLabel>
<deletedAxiom>&apos;cellular zinc ion homeostasis&apos; SubClassOf &apos;cellular divalent inorganic cation homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006885</classIRI>
<classLabel>regulation of pH</classLabel>
<deletedAxiom>&apos;regulation of pH&apos; SubClassOf &apos;monovalent inorganic cation homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;regulation of pH&apos; SubClassOf &apos;cation homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006812</classIRI>
<classLabel>cation transport</classLabel>
<deletedAxiom>&apos;cation transport&apos; SubClassOf &apos;has primary input&apos; some &apos;cation&apos;</deletedAxiom>
<deletedAxiom>&apos;cation transport&apos; EquivalentTo &apos;transport&apos; and (&apos;has primary input&apos; some &apos;cation&apos;)</deletedAxiom>
<newAxiom>&apos;cation transport&apos; SubClassOf &apos;has primary input&apos; some &apos;monoatomic cation&apos;</newAxiom>
<newAxiom>&apos;cation transport&apos; EquivalentTo &apos;transport&apos; and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006811</classIRI>
<classLabel>ion transport</classLabel>
<deletedAxiom>&apos;ion transport&apos; SubClassOf &apos;has primary input&apos; some &apos;ion&apos;</deletedAxiom>
<deletedAxiom>&apos;ion transport&apos; EquivalentTo &apos;transport&apos; and (&apos;has primary input&apos; some &apos;ion&apos;)</deletedAxiom>
<newAxiom>&apos;ion transport&apos; EquivalentTo &apos;transport&apos; and (&apos;has primary input&apos; some &apos;monoatomic ion&apos;)</newAxiom>
<newAxiom>&apos;ion transport&apos; SubClassOf &apos;has primary input&apos; some &apos;monoatomic ion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006821</classIRI>
<classLabel>chloride transport</classLabel>
<newAxiom>&apos;chloride transport&apos; SubClassOf &apos;anion transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006820</classIRI>
<classLabel>anion transport</classLabel>
<deletedAxiom>&apos;anion transport&apos; EquivalentTo &apos;transport&apos; and (&apos;has primary input&apos; some &apos;anion&apos;)</deletedAxiom>
<deletedAxiom>&apos;anion transport&apos; SubClassOf &apos;has primary input&apos; some &apos;anion&apos;</deletedAxiom>
<newAxiom>&apos;anion transport&apos; SubClassOf &apos;has primary input&apos; some &apos;monoatomic anion&apos;</newAxiom>
<newAxiom>&apos;anion transport&apos; EquivalentTo &apos;transport&apos; and (&apos;has primary input&apos; some &apos;monoatomic anion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006824</classIRI>
<classLabel>cobalt ion transport</classLabel>
<newAxiom>&apos;cobalt ion transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006837</classIRI>
<classLabel>serotonin transport</classLabel>
<deletedAxiom>&apos;serotonin transport&apos; SubClassOf &apos;cation transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006843</classIRI>
<classLabel>mitochondrial citrate transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial citrate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006588</classIRI>
<classLabel>activation of tryptophan 5-monooxygenase activity</classLabel>
<deletedAxiom>&apos;activation of tryptophan 5-monooxygenase activity&apos; SubClassOf &apos;part of&apos; some &apos;serotonin biosynthetic process from tryptophan&apos;</deletedAxiom>
<deletedAxiom>&apos;activation of tryptophan 5-monooxygenase activity&apos; SubClassOf &apos;positive regulation of monooxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006434</classIRI>
<classLabel>seryl-tRNA aminoacylation</classLabel>
<deletedAxiom>&apos;seryl-tRNA aminoacylation&apos; SubClassOf &apos;has_part&apos; some &apos;selenocysteinyl-tRNA(Sec) biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;seryl-tRNA aminoacylation&apos; SubClassOf &apos;has_part&apos; some &apos;conversion of seryl-tRNAsec to selenocys-tRNAsec&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031458</classIRI>
<classLabel>ABC-type betaine transporter activity</classLabel>
<deletedAxiom>&apos;ABC-type betaine transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031494</classIRI>
<classLabel>regulation of mating type switching</classLabel>
<deletedAxiom>&apos;regulation of mating type switching&apos; SubClassOf &apos;regulation of cell fate commitment&apos;</deletedAxiom>
<newAxiom>&apos;regulation of mating type switching&apos; SubClassOf &apos;regulation of developmental process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031496</classIRI>
<classLabel>positive regulation of mating type switching</classLabel>
<deletedAxiom>&apos;positive regulation of mating type switching&apos; SubClassOf &apos;positive regulation of cell fate commitment&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of mating type switching&apos; SubClassOf &apos;positive regulation of developmental process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031495</classIRI>
<classLabel>negative regulation of mating type switching</classLabel>
<deletedAxiom>&apos;negative regulation of mating type switching&apos; SubClassOf &apos;negative regulation of cell fate commitment&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of mating type switching&apos; SubClassOf &apos;negative regulation of developmental process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006309</classIRI>
<classLabel>apoptotic DNA fragmentation</classLabel>
<deletedAxiom>&apos;apoptotic DNA fragmentation&apos; SubClassOf &apos;DNA catabolic process, endonucleolytic&apos;</deletedAxiom>
<deletedAxiom>&apos;apoptotic DNA fragmentation&apos; EquivalentTo &apos;DNA catabolic process, endonucleolytic&apos; and (&apos;part of&apos; some &apos;apoptotic nuclear changes&apos;)</deletedAxiom>
<newAxiom>&apos;apoptotic DNA fragmentation&apos; SubClassOf &apos;DNA catabolic process&apos;</newAxiom>
<newAxiom>&apos;apoptotic DNA fragmentation&apos; EquivalentTo &apos;DNA catabolic process&apos; and (&apos;part of&apos; some &apos;apoptotic nuclear changes&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070914</classIRI>
<classLabel>UV-damage excision repair</classLabel>
<deletedAxiom>&apos;UV-damage excision repair&apos; SubClassOf &apos;starts with&apos; some &apos;UV-damage excision repair, DNA incision&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070907</classIRI>
<classLabel>histidine:histamine antiporter activity</classLabel>
<deletedAxiom>&apos;histidine:histamine antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;histidine:histamine antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070906</classIRI>
<classLabel>aspartate:alanine antiporter activity</classLabel>
<deletedAxiom>&apos;aspartate:alanine antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;aspartate:alanine antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;aspartate:alanine antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070909</classIRI>
<classLabel>glutamate:gamma-aminobutyric acid antiporter activity</classLabel>
<deletedAxiom>&apos;glutamate:gamma-aminobutyric acid antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;glutamate:gamma-aminobutyric acid antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;glutamate:gamma-aminobutyric acid antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070908</classIRI>
<classLabel>tyrosine:tyramine antiporter activity</classLabel>
<deletedAxiom>&apos;tyrosine:tyramine antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;tyrosine:tyramine antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070927</classIRI>
<classLabel>negative regulation of ATP:ADP antiporter activity</classLabel>
<deletedAxiom>&apos;negative regulation of ATP:ADP antiporter activity&apos; SubClassOf &apos;negative regulation of ion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of ATP:ADP antiporter activity&apos; SubClassOf &apos;negative regulation of transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070926</classIRI>
<classLabel>regulation of ATP:ADP antiporter activity</classLabel>
<deletedAxiom>&apos;regulation of ATP:ADP antiporter activity&apos; SubClassOf &apos;regulation of ion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;regulation of ATP:ADP antiporter activity&apos; SubClassOf &apos;regulation of transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070881</classIRI>
<classLabel>regulation of proline transport</classLabel>
<deletedAxiom>&apos;regulation of proline transport&apos; SubClassOf &apos;regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045830</classIRI>
<classLabel>positive regulation of isotype switching</classLabel>
<deletedAxiom>&apos;positive regulation of isotype switching&apos; SubClassOf &apos;positive regulation of multicellular organismal process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045829</classIRI>
<classLabel>negative regulation of isotype switching</classLabel>
<deletedAxiom>&apos;negative regulation of isotype switching&apos; SubClassOf &apos;negative regulation of multicellular organismal process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045870</classIRI>
<classLabel>positive regulation of single stranded viral RNA replication via double stranded DNA intermediate</classLabel>
<newAxiom>&apos;positive regulation of single stranded viral RNA replication via double stranded DNA intermediate&apos; SubClassOf &apos;positive regulation of RNA biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070835</classIRI>
<classLabel>chromium ion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;chromium ion transmembrane transporter activity&apos; SubClassOf &apos;ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045869</classIRI>
<classLabel>negative regulation of single stranded viral RNA replication via double stranded DNA intermediate</classLabel>
<newAxiom>&apos;negative regulation of single stranded viral RNA replication via double stranded DNA intermediate&apos; SubClassOf &apos;negative regulation of RNA biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070811</classIRI>
<classLabel>glycerol-2-phosphate transmembrane transport</classLabel>
<deletedAxiom>&apos;glycerol-2-phosphate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;glycerol-2-phosphate transmembrane transport&apos; SubClassOf &apos;transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006296</classIRI>
<classLabel>nucleotide-excision repair, DNA incision, 5&apos;-to lesion</classLabel>
<deletedAxiom>&apos;nucleotide-excision repair, DNA incision, 5&apos;-to lesion&apos; SubClassOf &apos;nucleotide-excision repair, DNA incision&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006295</classIRI>
<classLabel>nucleotide-excision repair, DNA incision, 3&apos;-to lesion</classLabel>
<deletedAxiom>&apos;nucleotide-excision repair, DNA incision, 3&apos;-to lesion&apos; SubClassOf &apos;nucleotide-excision repair, DNA incision&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045881</classIRI>
<classLabel>positive regulation of sporulation resulting in formation of a cellular spore</classLabel>
<deletedAxiom>&apos;positive regulation of sporulation resulting in formation of a cellular spore&apos; SubClassOf &apos;positive regulation of cell differentiation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031151</classIRI>
<classLabel>histone H3K79 methyltransferase activity</classLabel>
<newAxiom>&apos;histone H3K79 methyltransferase activity&apos; SubClassOf &apos;histone lysine N-methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0080145</classIRI>
<classLabel>cellular cysteine homeostasis</classLabel>
<deletedAxiom>&apos;cellular cysteine homeostasis&apos; SubClassOf &apos;cellular cation homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular cysteine homeostasis&apos; SubClassOf &apos;cellular anion homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070634</classIRI>
<classLabel>transepithelial ammonium transport</classLabel>
<deletedAxiom>&apos;transepithelial ammonium transport&apos; SubClassOf &apos;cation transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055083</classIRI>
<classLabel>monovalent inorganic anion homeostasis</classLabel>
<deletedAxiom>&apos;monovalent inorganic anion homeostasis&apos; SubClassOf &apos;inorganic ion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;monovalent inorganic anion homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;monovalent inorganic anion&apos;</deletedAxiom>
<deletedAxiom>&apos;monovalent inorganic anion homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;monovalent inorganic anion&apos;)</deletedAxiom>
<deletedAxiom>&apos;monovalent inorganic anion homeostasis&apos; SubClassOf &apos;anion homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055081</classIRI>
<classLabel>anion homeostasis</classLabel>
<deletedAxiom>&apos;anion homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;anion&apos;)</deletedAxiom>
<deletedAxiom>&apos;anion homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;anion&apos;</deletedAxiom>
<newAxiom>&apos;anion homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;monoatomic anion&apos;)</newAxiom>
<newAxiom>&apos;anion homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;monoatomic anion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055080</classIRI>
<classLabel>cation homeostasis</classLabel>
<deletedAxiom>&apos;cation homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;cation&apos;)</deletedAxiom>
<deletedAxiom>&apos;cation homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;cation&apos;</deletedAxiom>
<newAxiom>&apos;cation homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;monoatomic cation&apos;)</newAxiom>
<newAxiom>&apos;cation homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;monoatomic cation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055063</classIRI>
<classLabel>sulfate ion homeostasis</classLabel>
<deletedAxiom>&apos;sulfate ion homeostasis&apos; SubClassOf &apos;divalent inorganic anion homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;sulfate ion homeostasis&apos; SubClassOf &apos;inorganic ion homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055062</classIRI>
<classLabel>phosphate ion homeostasis</classLabel>
<deletedAxiom>&apos;phosphate ion homeostasis&apos; SubClassOf &apos;trivalent inorganic anion homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;phosphate ion homeostasis&apos; SubClassOf &apos;inorganic ion homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055069</classIRI>
<classLabel>zinc ion homeostasis</classLabel>
<deletedAxiom>&apos;zinc ion homeostasis&apos; SubClassOf &apos;divalent inorganic cation homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055067</classIRI>
<classLabel>monovalent inorganic cation homeostasis</classLabel>
<deletedAxiom>&apos;monovalent inorganic cation homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;monovalent inorganic cation&apos;</deletedAxiom>
<deletedAxiom>&apos;monovalent inorganic cation homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;monovalent inorganic cation&apos;)</deletedAxiom>
<deletedAxiom>&apos;monovalent inorganic cation homeostasis&apos; SubClassOf &apos;cation homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;monovalent inorganic cation homeostasis&apos; SubClassOf &apos;inorganic ion homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055064</classIRI>
<classLabel>chloride ion homeostasis</classLabel>
<deletedAxiom>&apos;chloride ion homeostasis&apos; SubClassOf &apos;monovalent inorganic anion homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;chloride ion homeostasis&apos; SubClassOf &apos;inorganic ion homeostasis&apos;</newAxiom>
<newAxiom>&apos;chloride ion homeostasis&apos; SubClassOf &apos;anion homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055074</classIRI>
<classLabel>calcium ion homeostasis</classLabel>
<deletedAxiom>&apos;calcium ion homeostasis&apos; SubClassOf &apos;divalent inorganic cation homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055073</classIRI>
<classLabel>cadmium ion homeostasis</classLabel>
<deletedAxiom>&apos;cadmium ion homeostasis&apos; SubClassOf &apos;divalent inorganic cation homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055078</classIRI>
<classLabel>sodium ion homeostasis</classLabel>
<deletedAxiom>&apos;sodium ion homeostasis&apos; SubClassOf &apos;monovalent inorganic cation homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055075</classIRI>
<classLabel>potassium ion homeostasis</classLabel>
<deletedAxiom>&apos;potassium ion homeostasis&apos; SubClassOf &apos;monovalent inorganic cation homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033561</classIRI>
<classLabel>regulation of water loss via skin</classLabel>
<deletedAxiom>&apos;regulation of water loss via skin&apos; SubClassOf &apos;multicellular organismal water homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008509</classIRI>
<classLabel>anion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;anion transmembrane transporter activity&apos; SubClassOf &apos;has primary input&apos; some &apos;anion&apos;</deletedAxiom>
<deletedAxiom>&apos;anion transmembrane transporter activity&apos; EquivalentTo &apos;transmembrane transporter activity&apos; and (&apos;has primary input&apos; some &apos;anion&apos;)</deletedAxiom>
<newAxiom>&apos;anion transmembrane transporter activity&apos; SubClassOf &apos;has primary input&apos; some &apos;monoatomic anion&apos;</newAxiom>
<newAxiom>&apos;anion transmembrane transporter activity&apos; EquivalentTo &apos;transmembrane transporter activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic anion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008513</classIRI>
<classLabel>secondary active organic cation transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;secondary active organic cation transmembrane transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008512</classIRI>
<classLabel>sulfate:proton symporter activity</classLabel>
<deletedAxiom>&apos;sulfate:proton symporter activity&apos; SubClassOf &apos;anion:cation symporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008514</classIRI>
<classLabel>organic anion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;organic anion transmembrane transporter activity&apos; SubClassOf &apos;anion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;organic anion transmembrane transporter activity&apos; SubClassOf &apos;transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008519</classIRI>
<classLabel>ammonium transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;ammonium transmembrane transporter activity&apos; SubClassOf &apos;cation channel activity&apos;</deletedAxiom>
<newAxiom>&apos;ammonium transmembrane transporter activity&apos; SubClassOf &apos;channel activity&apos;</newAxiom>
<newAxiom>&apos;ammonium transmembrane transporter activity&apos; SubClassOf &apos;inorganic cation transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008518</classIRI>
<classLabel>folate:anion antiporter activity</classLabel>
<deletedAxiom>&apos;folate:anion antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;anion&apos;) and (&apos;has primary input&apos; some &apos;folate(2-)&apos;)</deletedAxiom>
<deletedAxiom>&apos;folate:anion antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;folate:anion antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
<newAxiom>&apos;folate:anion antiporter activity&apos; SubClassOf &apos;anion transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;folate:anion antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic anion&apos;) and (&apos;has primary input&apos; some &apos;folate(2-)&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008490</classIRI>
<classLabel>arsenite secondary active transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;arsenite secondary active transmembrane transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008381</classIRI>
<classLabel>mechanosensitive ion channel activity</classLabel>
<deletedAxiom>&apos;mechanosensitive ion channel activity&apos; SubClassOf &apos;gated channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;mechanosensitive ion channel activity&apos; SubClassOf &apos;ion channel activity&apos;</deletedAxiom>
<newAxiom>&apos;mechanosensitive ion channel activity&apos; SubClassOf &apos;ion gated channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008308</classIRI>
<classLabel>voltage-gated anion channel activity</classLabel>
<deletedAxiom>&apos;voltage-gated anion channel activity&apos; EquivalentTo &apos;voltage-gated channel activity&apos; and (&apos;has primary input&apos; some &apos;inorganic anion&apos;)</deletedAxiom>
<newAxiom>&apos;voltage-gated anion channel activity&apos; EquivalentTo &apos;voltage-gated channel activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic anion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008324</classIRI>
<classLabel>cation transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;cation transmembrane transporter activity&apos; EquivalentTo &apos;transmembrane transporter activity&apos; and (&apos;has primary input&apos; some &apos;cation&apos;)</deletedAxiom>
<deletedAxiom>&apos;cation transmembrane transporter activity&apos; SubClassOf &apos;has primary input&apos; some &apos;cation&apos;</deletedAxiom>
<newAxiom>&apos;cation transmembrane transporter activity&apos; EquivalentTo &apos;transmembrane transporter activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</newAxiom>
<newAxiom>&apos;cation transmembrane transporter activity&apos; SubClassOf &apos;has primary input&apos; some &apos;monoatomic cation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033229</classIRI>
<classLabel>cysteine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;cysteine transmembrane transporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008271</classIRI>
<classLabel>secondary active sulfate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;secondary active sulfate transmembrane transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033230</classIRI>
<classLabel>ABC-type cysteine transporter activity</classLabel>
<deletedAxiom>&apos;ABC-type cysteine transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033232</classIRI>
<classLabel>ABC-type D-methionine transporter activity</classLabel>
<deletedAxiom>&apos;ABC-type D-methionine transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033266</classIRI>
<classLabel>ABC-type choline transporter activity</classLabel>
<deletedAxiom>&apos;ABC-type choline transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033286</classIRI>
<classLabel>ATPase-coupled ectoine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;ATPase-coupled ectoine transmembrane transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033288</classIRI>
<classLabel>ATPase-coupled hydroxyectoine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;ATPase-coupled hydroxyectoine transmembrane transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106421</classIRI>
<classLabel>L-glutamate:proton antiporter activity</classLabel>
<deletedAxiom>&apos;L-glutamate:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;L-glutamate:proton antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;L-glutamate(1-)&apos;)</deletedAxiom>
<deletedAxiom>&apos;L-glutamate:proton antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;L-glutamate:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;L-glutamate(1-)&apos;)</newAxiom>
<newAxiom>&apos;L-glutamate:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072501</classIRI>
<classLabel>cellular divalent inorganic anion homeostasis</classLabel>
<deletedAxiom>&apos;cellular divalent inorganic anion homeostasis&apos; SubClassOf &apos;divalent inorganic anion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular divalent inorganic anion homeostasis&apos; SubClassOf &apos;cellular anion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular divalent inorganic anion homeostasis&apos; EquivalentTo &apos;cellular homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;divalent inorganic anion&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072503</classIRI>
<classLabel>cellular divalent inorganic cation homeostasis</classLabel>
<deletedAxiom>&apos;cellular divalent inorganic cation homeostasis&apos; EquivalentTo &apos;cellular chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;divalent inorganic cation&apos;)</deletedAxiom>
<deletedAxiom>&apos;cellular divalent inorganic cation homeostasis&apos; SubClassOf &apos;cellular cation homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular divalent inorganic cation homeostasis&apos; SubClassOf &apos;divalent inorganic cation homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072502</classIRI>
<classLabel>cellular trivalent inorganic anion homeostasis</classLabel>
<deletedAxiom>&apos;cellular trivalent inorganic anion homeostasis&apos; SubClassOf &apos;cellular anion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular trivalent inorganic anion homeostasis&apos; SubClassOf &apos;trivalent inorganic anion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular trivalent inorganic anion homeostasis&apos; EquivalentTo &apos;cellular homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;trivalent inorganic anion&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072505</classIRI>
<classLabel>divalent inorganic anion homeostasis</classLabel>
<deletedAxiom>&apos;divalent inorganic anion homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;divalent inorganic anion&apos;)</deletedAxiom>
<deletedAxiom>&apos;divalent inorganic anion homeostasis&apos; SubClassOf &apos;anion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;divalent inorganic anion homeostasis&apos; SubClassOf &apos;inorganic ion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;divalent inorganic anion homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;divalent inorganic anion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072504</classIRI>
<classLabel>cellular trivalent inorganic cation homeostasis</classLabel>
<deletedAxiom>&apos;cellular trivalent inorganic cation homeostasis&apos; EquivalentTo &apos;cellular chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;trivalent inorganic cation&apos;)</deletedAxiom>
<deletedAxiom>&apos;cellular trivalent inorganic cation homeostasis&apos; SubClassOf &apos;cellular cation homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular trivalent inorganic cation homeostasis&apos; SubClassOf &apos;trivalent inorganic cation homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072507</classIRI>
<classLabel>divalent inorganic cation homeostasis</classLabel>
<deletedAxiom>&apos;divalent inorganic cation homeostasis&apos; SubClassOf &apos;cation homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;divalent inorganic cation homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;divalent inorganic cation&apos;</deletedAxiom>
<deletedAxiom>&apos;divalent inorganic cation homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;divalent inorganic cation&apos;)</deletedAxiom>
<deletedAxiom>&apos;divalent inorganic cation homeostasis&apos; SubClassOf &apos;inorganic ion homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072506</classIRI>
<classLabel>trivalent inorganic anion homeostasis</classLabel>
<deletedAxiom>&apos;trivalent inorganic anion homeostasis&apos; SubClassOf &apos;inorganic ion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;trivalent inorganic anion homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;trivalent inorganic anion&apos;)</deletedAxiom>
<deletedAxiom>&apos;trivalent inorganic anion homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;trivalent inorganic anion&apos;</deletedAxiom>
<deletedAxiom>&apos;trivalent inorganic anion homeostasis&apos; SubClassOf &apos;anion homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072508</classIRI>
<classLabel>trivalent inorganic cation homeostasis</classLabel>
<deletedAxiom>&apos;trivalent inorganic cation homeostasis&apos; SubClassOf &apos;regulates levels of&apos; some &apos;trivalent inorganic cation&apos;</deletedAxiom>
<deletedAxiom>&apos;trivalent inorganic cation homeostasis&apos; SubClassOf &apos;inorganic ion homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;trivalent inorganic cation homeostasis&apos; EquivalentTo &apos;chemical homeostasis&apos; and (&apos;regulates levels of&apos; some &apos;trivalent inorganic cation&apos;)</deletedAxiom>
<deletedAxiom>&apos;trivalent inorganic cation homeostasis&apos; SubClassOf &apos;cation homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072562</classIRI>
<classLabel>blood microparticle</classLabel>
<newAxiom>&apos;blood microparticle&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eumetazoa&apos;</newAxiom>
<newAxiom>&apos;blood microparticle&apos; SubClassOf &apos;in taxon&apos; only &apos;Eumetazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072489</classIRI>
<classLabel>methylammonium transmembrane transport</classLabel>
<deletedAxiom>&apos;methylammonium transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;methylammonium transmembrane transport&apos; SubClassOf &apos;transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072334</classIRI>
<classLabel>UDP-galactose transmembrane transport</classLabel>
<deletedAxiom>&apos;UDP-galactose transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CL_1000839</classIRI>
<classLabel>kidney proximal straight tubule epithelial cell</classLabel>
<deletedAxiom>&apos;kidney proximal straight tubule epithelial cell&apos; SubClassOf &apos;kidney loop of Henle epithelial cell&apos;</deletedAxiom>
<newAxiom>&apos;kidney proximal straight tubule epithelial cell&apos; SubClassOf http://purl.obolibrary.org/obo/CL_1001021</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052929</classIRI>
<classLabel>ATP:3&apos;-cytidine-cytidine-tRNA adenylyltransferase activity</classLabel>
<newAxiom>&apos;ATP:3&apos;-cytidine-cytidine-tRNA adenylyltransferase activity&apos; SubClassOf &apos;catalytic activity, acting on a tRNA&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903091</classIRI>
<classLabel>pyridoxamine transmembrane transport</classLabel>
<deletedAxiom>&apos;pyridoxamine transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903090</classIRI>
<classLabel>pyridoxal transmembrane transport</classLabel>
<deletedAxiom>&apos;pyridoxal transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062122</classIRI>
<classLabel>histone H3K37 methyltransferase activity</classLabel>
<newAxiom>&apos;histone H3K37 methyltransferase activity&apos; SubClassOf &apos;histone lysine N-methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062158</classIRI>
<classLabel>chloride:proton antiporter activity</classLabel>
<deletedAxiom>&apos;chloride:proton antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;chloride&apos;) and (&apos;has primary input&apos; some &apos;proton&apos;)</deletedAxiom>
<deletedAxiom>&apos;chloride:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;chloride:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;chloride&apos;) and (&apos;has primary input&apos; some &apos;proton&apos;)</newAxiom>
<newAxiom>&apos;chloride:proton antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;chloride:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062057</classIRI>
<classLabel>L-aspartate:fumarate antiporter activity</classLabel>
<deletedAxiom>&apos;L-aspartate:fumarate antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;L-aspartate:fumarate antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;L-aspartate:fumarate antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990551</classIRI>
<classLabel>mitochondrial 2-oxoadipate transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial 2-oxoadipate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990550</classIRI>
<classLabel>mitochondrial alpha-ketoglutarate transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial alpha-ketoglutarate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990544</classIRI>
<classLabel>mitochondrial ATP transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial ATP transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990569</classIRI>
<classLabel>UDP-N-acetylglucosamine transmembrane transport</classLabel>
<deletedAxiom>&apos;UDP-N-acetylglucosamine transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990523</classIRI>
<classLabel>bone regeneration</classLabel>
<newAxiom>&apos;bone regeneration&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eumetazoa&apos;</newAxiom>
<newAxiom>&apos;bone regeneration&apos; SubClassOf &apos;in taxon&apos; only &apos;Eumetazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902022</classIRI>
<classLabel>L-lysine transport</classLabel>
<deletedAxiom>&apos;L-lysine transport&apos; SubClassOf &apos;cation transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902024</classIRI>
<classLabel>L-histidine transport</classLabel>
<deletedAxiom>&apos;L-histidine transport&apos; SubClassOf &apos;cation transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990731</classIRI>
<classLabel>UV-damage excision repair, DNA incision</classLabel>
<deletedAxiom>&apos;UV-damage excision repair, DNA incision&apos; SubClassOf &apos;nucleic acid phosphodiester bond hydrolysis&apos;</deletedAxiom>
<deletedAxiom>&apos;UV-damage excision repair, DNA incision&apos; SubClassOf &apos;part of&apos; some &apos;UV-damage excision repair&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990760</classIRI>
<classLabel>osmolarity-sensing cation channel activity</classLabel>
<deletedAxiom>&apos;osmolarity-sensing cation channel activity&apos; SubClassOf &apos;gated channel activity&apos;</deletedAxiom>
<newAxiom>&apos;osmolarity-sensing cation channel activity&apos; SubClassOf &apos;inorganic cation transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;osmolarity-sensing cation channel activity&apos; SubClassOf &apos;ion gated channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042960</classIRI>
<classLabel>antimonite secondary active transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;antimonite secondary active transmembrane transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042962</classIRI>
<classLabel>acridine:proton antiporter activity</classLabel>
<deletedAxiom>&apos;acridine:proton antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;acridine&apos;)</deletedAxiom>
<deletedAxiom>&apos;acridine:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;acridine:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;acridine&apos;)</newAxiom>
<newAxiom>&apos;acridine:proton antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;acridine:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;acridine:proton antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042883</classIRI>
<classLabel>cysteine transport</classLabel>
<deletedAxiom>&apos;cysteine transport&apos; SubClassOf &apos;cation transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902265</classIRI>
<classLabel>abscisic acid homeostasis</classLabel>
<deletedAxiom>&apos;abscisic acid homeostasis&apos; SubClassOf &apos;anion homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902266</classIRI>
<classLabel>cellular abscisic acid homeostasis</classLabel>
<deletedAxiom>&apos;cellular abscisic acid homeostasis&apos; SubClassOf &apos;cellular anion homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;cellular abscisic acid homeostasis&apos; SubClassOf &apos;cellular chemical homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042873</classIRI>
<classLabel>aldonate transmembrane transport</classLabel>
<deletedAxiom>&apos;aldonate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;aldonate transmembrane transport&apos; SubClassOf &apos;transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902272</classIRI>
<classLabel>regulation of (R)-carnitine transmembrane transport</classLabel>
<deletedAxiom>&apos;regulation of (R)-carnitine transmembrane transport&apos; SubClassOf &apos;regulation of cation transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;regulation of (R)-carnitine transmembrane transport&apos; SubClassOf &apos;regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902274</classIRI>
<classLabel>positive regulation of (R)-carnitine transmembrane transport</classLabel>
<deletedAxiom>&apos;positive regulation of (R)-carnitine transmembrane transport&apos; SubClassOf &apos;positive regulation of cation transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of (R)-carnitine transmembrane transport&apos; SubClassOf &apos;positive regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902273</classIRI>
<classLabel>negative regulation of (R)-carnitine transmembrane transport</classLabel>
<deletedAxiom>&apos;negative regulation of (R)-carnitine transmembrane transport&apos; SubClassOf &apos;negative regulation of cation transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of (R)-carnitine transmembrane transport&apos; SubClassOf &apos;negative regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042869</classIRI>
<classLabel>aldarate transmembrane transport</classLabel>
<deletedAxiom>&apos;aldarate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;aldarate transmembrane transport&apos; SubClassOf &apos;transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990818</classIRI>
<classLabel>L-arginine transmembrane export from vacuole</classLabel>
<deletedAxiom>&apos;L-arginine transmembrane export from vacuole&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;L-arginine transmembrane export from vacuole&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042800</classIRI>
<classLabel>histone H3K4 methyltransferase activity</classLabel>
<newAxiom>&apos;histone H3K4 methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;histone H3K4 methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
<newAxiom>&apos;histone H3K4 methyltransferase activity&apos; SubClassOf &apos;histone lysine N-methyltransferase activity&apos;</newAxiom>
<newAxiom>&apos;histone H3K4 methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;N(6),N(6),N(6)-trimethyl-L-lysine residue&apos;</newAxiom>
<newAxiom>&apos;histone H3K4 methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;L-lysinium residue&apos;</newAxiom>
<newAxiom>&apos;histone H3K4 methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902357</classIRI>
<classLabel>2-isopropylmalate(2-) transmembrane transport</classLabel>
<deletedAxiom>&apos;2-isopropylmalate(2-) transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902356</classIRI>
<classLabel>oxaloacetate(2-) transmembrane transport</classLabel>
<deletedAxiom>&apos;oxaloacetate(2-) transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042792</classIRI>
<classLabel>mitochondrial rRNA transcription</classLabel>
<deletedAxiom>&apos;mitochondrial rRNA transcription&apos; SubClassOf &apos;rRNA transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;mitochondrial rRNA transcription&apos; EquivalentTo &apos;mitochondrial transcription&apos; and (&apos;has primary output&apos; some &apos;rRNA&apos;)</deletedAxiom>
<deletedAxiom>&apos;mitochondrial rRNA transcription&apos; SubClassOf &apos;mitochondrial transcription&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902559</classIRI>
<classLabel>3&apos;-phospho-5&apos;-adenylyl sulfate transmembrane transport</classLabel>
<deletedAxiom>&apos;3&apos;-phospho-5&apos;-adenylyl sulfate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902558</classIRI>
<classLabel>5&apos;-adenylyl sulfate transmembrane transport</classLabel>
<deletedAxiom>&apos;5&apos;-adenylyl sulfate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902476</classIRI>
<classLabel>chloride transmembrane transport</classLabel>
<newAxiom>&apos;chloride transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902600</classIRI>
<classLabel>proton transmembrane transport</classLabel>
<newAxiom>&apos;proton transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902603</classIRI>
<classLabel>carnitine transmembrane transport</classLabel>
<deletedAxiom>&apos;carnitine transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;carnitine transmembrane transport&apos; SubClassOf &apos;transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902604</classIRI>
<classLabel>p-aminobenzoyl-glutamate transmembrane transport</classLabel>
<deletedAxiom>&apos;p-aminobenzoyl-glutamate transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140952</classIRI>
<classLabel>histone H3K27 dimethyltransferase activity</classLabel>
<newAxiom>&apos;histone H3K27 dimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
<newAxiom>&apos;histone H3K27 dimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;L-lysinium residue&apos;</newAxiom>
<newAxiom>&apos;histone H3K27 dimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;histone H3K27 dimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;N(6),N(6)-dimethyl-L-lysine(1+) residue&apos;</newAxiom>
<newAxiom>&apos;histone H3K27 dimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140951</classIRI>
<classLabel>histone H3K27 trimethyltransferase activity</classLabel>
<newAxiom>&apos;histone H3K27 trimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
<newAxiom>&apos;histone H3K27 trimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;N(6),N(6),N(6)-trimethyl-L-lysine residue&apos;</newAxiom>
<newAxiom>&apos;histone H3K27 trimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</newAxiom>
<newAxiom>&apos;histone H3K27 trimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;histone H3K27 trimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;L-lysinium residue&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140956</classIRI>
<classLabel>histone H3K79 trimethyltransferase activity</classLabel>
<newAxiom>&apos;histone H3K79 trimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;L-lysinium residue&apos;</newAxiom>
<newAxiom>&apos;histone H3K79 trimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</newAxiom>
<newAxiom>&apos;histone H3K79 trimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;N(6),N(6),N(6)-trimethyl-L-lysine residue&apos;</newAxiom>
<newAxiom>&apos;histone H3K79 trimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;histone H3K79 trimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140955</classIRI>
<classLabel>histone H3K36 trimethyltransferase activity</classLabel>
<newAxiom>&apos;histone H3K36 trimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
<newAxiom>&apos;histone H3K36 trimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;L-lysinium residue&apos;</newAxiom>
<newAxiom>&apos;histone H3K36 trimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;N(6),N(6),N(6)-trimethyl-L-lysine residue&apos;</newAxiom>
<newAxiom>&apos;histone H3K36 trimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;histone H3K36 trimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140954</classIRI>
<classLabel>histone H3K36 dimethyltransferase activity</classLabel>
<newAxiom>&apos;histone H3K36 dimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;histone H3K36 dimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;N(6),N(6)-dimethyl-L-lysine(1+) residue&apos;</newAxiom>
<newAxiom>&apos;histone H3K36 dimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;L-lysinium residue&apos;</newAxiom>
<newAxiom>&apos;histone H3K36 dimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</newAxiom>
<newAxiom>&apos;histone H3K36 dimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140953</classIRI>
<classLabel>histone H3K27 monomethyltransferase activity</classLabel>
<newAxiom>&apos;histone H3K27 monomethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;histone H3K27 monomethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;N(6)-methyl-L-lysinium residue&apos;</newAxiom>
<newAxiom>&apos;histone H3K27 monomethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;L-lysinium residue&apos;</newAxiom>
<newAxiom>&apos;histone H3K27 monomethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
<newAxiom>&apos;histone H3K27 monomethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140949</classIRI>
<classLabel>histone H3K9 trimethyltransferase activity</classLabel>
<newAxiom>&apos;histone H3K9 trimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;L-lysinium residue&apos;</newAxiom>
<newAxiom>&apos;histone H3K9 trimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
<newAxiom>&apos;histone H3K9 trimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;N(6),N(6),N(6)-trimethyl-L-lysine residue&apos;</newAxiom>
<newAxiom>&apos;histone H3K9 trimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;histone H3K9 trimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140948</classIRI>
<classLabel>histone H3K9 monomethyltransferase activity</classLabel>
<newAxiom>&apos;histone H3K9 monomethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
<newAxiom>&apos;histone H3K9 monomethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</newAxiom>
<newAxiom>&apos;histone H3K9 monomethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;histone H3K9 monomethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;N(6),N(6)-dimethyl-L-lysine(1+) residue&apos;</newAxiom>
<newAxiom>&apos;histone H3K9 monomethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;N(6),N(6),N(6)-trimethyl-L-lysine residue&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140947</classIRI>
<classLabel>histone H3K9me2 methyltransferase activity</classLabel>
<newAxiom>&apos;histone H3K9me2 methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;L-lysinium residue&apos;</newAxiom>
<newAxiom>&apos;histone H3K9me2 methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
<newAxiom>&apos;histone H3K9me2 methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;N(6)-methyl-L-lysinium residue&apos;</newAxiom>
<newAxiom>&apos;histone H3K9me2 methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</newAxiom>
<newAxiom>&apos;histone H3K9me2 methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140946</classIRI>
<classLabel>histone H3K4 dimethyltransferase activity</classLabel>
<newAxiom>&apos;histone H3K4 dimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
<newAxiom>&apos;histone H3K4 dimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;histone H3K4 dimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;L-lysinium residue&apos;</newAxiom>
<newAxiom>&apos;histone H3K4 dimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;N(6),N(6)-dimethyl-L-lysine(1+) residue&apos;</newAxiom>
<newAxiom>&apos;histone H3K4 dimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140941</classIRI>
<classLabel>histone H4K20me methyltransferase activity</classLabel>
<newAxiom>&apos;histone H4K20me methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;N(6),N(6)-dimethyl-L-lysine(1+) residue&apos;</newAxiom>
<newAxiom>&apos;histone H4K20me methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;N(6)-methyl-L-lysinium residue&apos;</newAxiom>
<newAxiom>&apos;histone H4K20me methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</newAxiom>
<newAxiom>&apos;histone H4K20me methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
<newAxiom>&apos;histone H4K20me methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140945</classIRI>
<classLabel>histone H3K4 monomethyltransferase activity</classLabel>
<newAxiom>&apos;histone H3K4 monomethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;histone H3K4 monomethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;L-lysinium residue&apos;</newAxiom>
<newAxiom>&apos;histone H3K4 monomethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
<newAxiom>&apos;histone H3K4 monomethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;N(6)-methyl-L-lysinium residue&apos;</newAxiom>
<newAxiom>&apos;histone H3K4 monomethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140944</classIRI>
<classLabel>histone H4K20 monomethyltransferase activity</classLabel>
<newAxiom>&apos;histone H4K20 monomethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;histone H4K20 monomethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
<newAxiom>&apos;histone H4K20 monomethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;N(6)-methyl-L-lysinium residue&apos;</newAxiom>
<newAxiom>&apos;histone H4K20 monomethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;L-lysinium residue&apos;</newAxiom>
<newAxiom>&apos;histone H4K20 monomethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140943</classIRI>
<classLabel>histone H4K20 trimethyltransferase activity</classLabel>
<newAxiom>&apos;histone H4K20 trimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;L-lysinium residue&apos;</newAxiom>
<newAxiom>&apos;histone H4K20 trimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
<newAxiom>&apos;histone H4K20 trimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;histone H4K20 trimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;N(6),N(6),N(6)-trimethyl-L-lysine residue&apos;</newAxiom>
<newAxiom>&apos;histone H4K20 trimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140942</classIRI>
<classLabel>histone H3K9 dimethyltransferase activity</classLabel>
<newAxiom>&apos;histone H3K9 dimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</newAxiom>
<newAxiom>&apos;histone H3K9 dimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;L-lysinium residue&apos;</newAxiom>
<newAxiom>&apos;histone H3K9 dimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
<newAxiom>&apos;histone H3K9 dimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;N(6),N(6)-dimethyl-L-lysine(1+) residue&apos;</newAxiom>
<newAxiom>&apos;histone H3K9 dimethyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140925</classIRI>
<classLabel>L-phenylalanine import across plasma membrane</classLabel>
<deletedAxiom>&apos;L-phenylalanine import across plasma membrane&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;L-phenylalanine import across plasma membrane&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140924</classIRI>
<classLabel>L-kynurenine transmembrane transport</classLabel>
<deletedAxiom>&apos;L-kynurenine transmembrane transport&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902702</classIRI>
<classLabel>hexose catabolic process to propan-2-ol</classLabel>
<deletedAxiom>&apos;hexose catabolic process to propan-2-ol&apos; SubClassOf &apos;propan-2-ol metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to propan-2-ol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some &apos;propan-2-ol&apos;) and (&apos;has primary input&apos; some &apos;hexose&apos;)</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to propan-2-ol&apos; SubClassOf &apos;hexose catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to propan-2-ol&apos; SubClassOf &apos;has primary output&apos; some &apos;propan-2-ol&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902704</classIRI>
<classLabel>hexose catabolic process to acetone</classLabel>
<deletedAxiom>&apos;hexose catabolic process to acetone&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some &apos;acetone&apos;) and (&apos;has primary input&apos; some &apos;hexose&apos;)</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to acetone&apos; SubClassOf &apos;acetone metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to acetone&apos; SubClassOf &apos;has primary output&apos; some &apos;acetone&apos;</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to acetone&apos; SubClassOf &apos;hexose catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902703</classIRI>
<classLabel>hexose catabolic process to butan-1-ol</classLabel>
<deletedAxiom>&apos;hexose catabolic process to butan-1-ol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some &apos;butan-1-ol&apos;) and (&apos;has primary input&apos; some &apos;hexose&apos;)</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to butan-1-ol&apos; SubClassOf &apos;hexose catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to butan-1-ol&apos; SubClassOf &apos;1-butanol metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to butan-1-ol&apos; SubClassOf &apos;has primary output&apos; some &apos;butan-1-ol&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902706</classIRI>
<classLabel>hexose catabolic process to acetate</classLabel>
<deletedAxiom>&apos;hexose catabolic process to acetate&apos; SubClassOf &apos;acetate metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to acetate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some &apos;acetate&apos;) and (&apos;has primary input&apos; some &apos;hexose&apos;)</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to acetate&apos; SubClassOf &apos;hexose catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to acetate&apos; SubClassOf &apos;has primary output&apos; some &apos;acetate&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902705</classIRI>
<classLabel>hexose catabolic process to butyrate</classLabel>
<deletedAxiom>&apos;hexose catabolic process to butyrate&apos; SubClassOf &apos;butyrate metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to butyrate&apos; SubClassOf &apos;hexose catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to butyrate&apos; SubClassOf &apos;has primary output&apos; some &apos;butyrate&apos;</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to butyrate&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some &apos;butyrate&apos;) and (&apos;has primary input&apos; some &apos;hexose&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902707</classIRI>
<classLabel>hexose catabolic process to ethanol</classLabel>
<deletedAxiom>&apos;hexose catabolic process to ethanol&apos; SubClassOf &apos;ethanol metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to ethanol&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary output&apos; some &apos;ethanol&apos;) and (&apos;has primary input&apos; some &apos;hexose&apos;)</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to ethanol&apos; SubClassOf &apos;hexose catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;hexose catabolic process to ethanol&apos; SubClassOf &apos;has primary output&apos; some &apos;ethanol&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140893</classIRI>
<classLabel>neutral amino acid, sodium:proton antiporter activity</classLabel>
<deletedAxiom>&apos;neutral amino acid, sodium:proton antiporter activity&apos; SubClassOf &apos;has primary input&apos; some &apos;amino acid zwitterion&apos;</deletedAxiom>
<deletedAxiom>&apos;neutral amino acid, sodium:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;sodium(1+)&apos;) and (&apos;has primary input&apos; some &apos;amino acid zwitterion&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140848</classIRI>
<classLabel>amino acid:monoatomic cation antiporter activity</classLabel>
<deletedAxiom>&apos;amino acid:monoatomic cation antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;amino acid:monoatomic cation antiporter activity&apos; SubClassOf &apos;has primary input&apos; some &apos;monoatomic cation&apos;</deletedAxiom>
<deletedAxiom>&apos;amino acid:monoatomic cation antiporter activity&apos; EquivalentTo &apos;solute:cation antiporter activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;) and (&apos;has primary input&apos; some &apos;amino acid&apos;)</deletedAxiom>
<newAxiom>&apos;amino acid:monoatomic cation antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;) and (&apos;has primary input&apos; some &apos;amino acid&apos;)</newAxiom>
<newAxiom>&apos;amino acid:monoatomic cation antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;amino acid:monoatomic cation antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
<newAxiom>&apos;amino acid:monoatomic cation antiporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140831</classIRI>
<classLabel>L-asparagine, sodium:proton antiporter activity</classLabel>
<deletedAxiom>&apos;L-asparagine, sodium:proton antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;sodium(1+)&apos;) and (&apos;has primary input&apos; some &apos;L-asparagine zwitterion&apos;)</deletedAxiom>
<deletedAxiom>&apos;L-asparagine, sodium:proton antiporter activity&apos; SubClassOf &apos;neutral amino acid, sodium:proton antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;L-asparagine, sodium:proton antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;L-asparagine, sodium:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;sodium(1+)&apos;) and (&apos;has primary input&apos; some &apos;L-asparagine zwitterion&apos;)</newAxiom>
<newAxiom>&apos;L-asparagine, sodium:proton antiporter activity&apos; SubClassOf &apos;sodium:proton antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140830</classIRI>
<classLabel>L-glutamine, sodium:proton antiporter activity</classLabel>
<deletedAxiom>&apos;L-glutamine, sodium:proton antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;sodium(1+)&apos;) and (&apos;has primary input&apos; some &apos;L-glutamine zwitterion&apos;)</deletedAxiom>
<deletedAxiom>&apos;L-glutamine, sodium:proton antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;L-glutamine, sodium:proton antiporter activity&apos; SubClassOf &apos;neutral amino acid, sodium:proton antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;L-glutamine, sodium:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;sodium(1+)&apos;) and (&apos;has primary input&apos; some &apos;L-glutamine zwitterion&apos;)</newAxiom>
<newAxiom>&apos;L-glutamine, sodium:proton antiporter activity&apos; SubClassOf &apos;sodium:proton antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140832</classIRI>
<classLabel>L-histidine, sodium:proton antiporter activity</classLabel>
<deletedAxiom>&apos;L-histidine, sodium:proton antiporter activity&apos; SubClassOf &apos;neutral amino acid, sodium:proton antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;L-histidine, sodium:proton antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;sodium(1+)&apos;) and (&apos;has primary input&apos; some &apos;L-histidine zwitterion&apos;)</deletedAxiom>
<deletedAxiom>&apos;L-histidine, sodium:proton antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;L-histidine, sodium:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;sodium(1+)&apos;) and (&apos;has primary input&apos; some &apos;L-histidine zwitterion&apos;)</newAxiom>
<newAxiom>&apos;L-histidine, sodium:proton antiporter activity&apos; SubClassOf &apos;sodium:proton antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140828</classIRI>
<classLabel>metal cation:monoatomic cation antiporter activity</classLabel>
<deletedAxiom>&apos;metal cation:monoatomic cation antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;metal cation:monoatomic cation antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
<newAxiom>&apos;metal cation:monoatomic cation antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140826</classIRI>
<classLabel>zinc:proton antiporter activity</classLabel>
<deletedAxiom>&apos;zinc:proton antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;zinc cation&apos;)</deletedAxiom>
<newAxiom>&apos;zinc:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;zinc cation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140829</classIRI>
<classLabel>bicarbonate:anion antiporter activity</classLabel>
<deletedAxiom>&apos;bicarbonate:anion antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;bicarbonate:anion antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;hydrogencarbonate&apos;) and (&apos;has primary input&apos; some &apos;anion&apos;)</deletedAxiom>
<newAxiom>&apos;bicarbonate:anion antiporter activity&apos; SubClassOf &apos;anion transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;bicarbonate:anion antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
<newAxiom>&apos;bicarbonate:anion antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;hydrogencarbonate&apos;) and (&apos;has primary input&apos; some &apos;monoatomic anion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140821</classIRI>
<classLabel>UDP-beta-L-arabinofuranose import into Golgi lumen</classLabel>
<deletedAxiom>&apos;UDP-beta-L-arabinofuranose import into Golgi lumen&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140813</classIRI>
<classLabel>urate:anion antiporter activity</classLabel>
<deletedAxiom>&apos;urate:anion antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;urate:anion antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;7,9-dihydro-1H-purine-2,6,8(3H)-trione&apos;) and (&apos;has primary input&apos; some &apos;anion&apos;)</deletedAxiom>
<newAxiom>&apos;urate:anion antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;7,9-dihydro-1H-purine-2,6,8(3H)-trione&apos;) and (&apos;has primary input&apos; some &apos;monoatomic anion&apos;)</newAxiom>
<newAxiom>&apos;urate:anion antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
<newAxiom>&apos;urate:anion antiporter activity&apos; SubClassOf &apos;anion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140812</classIRI>
<classLabel>orotate:anion antiporter activity</classLabel>
<deletedAxiom>&apos;orotate:anion antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;anion&apos;) and (&apos;has primary input&apos; some &apos;orotate&apos;)</deletedAxiom>
<deletedAxiom>&apos;orotate:anion antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;orotate:anion antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic anion&apos;) and (&apos;has primary input&apos; some &apos;orotate&apos;)</newAxiom>
<newAxiom>&apos;orotate:anion antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</newAxiom>
<newAxiom>&apos;orotate:anion antiporter activity&apos; SubClassOf &apos;anion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140800</classIRI>
<classLabel>gamma-aminobutyric acid:proton antiporter activity</classLabel>
<deletedAxiom>&apos;gamma-aminobutyric acid:proton antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;gamma-aminobutyric acid:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;gamma-aminobutyric acid:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140799</classIRI>
<classLabel>glycine:proton antiporter activity</classLabel>
<deletedAxiom>&apos;glycine:proton antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;glycine zwitterion&apos;)</deletedAxiom>
<deletedAxiom>&apos;glycine:proton antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;glycine:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;glycine:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;glycine:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;glycine zwitterion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140787</classIRI>
<classLabel>phosphate ion uniporter activity</classLabel>
<deletedAxiom>&apos;phosphate ion uniporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140788</classIRI>
<classLabel>L-glutamate uniporter activity</classLabel>
<deletedAxiom>&apos;L-glutamate uniporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140759</classIRI>
<classLabel>histone H3K56 methyltransferase activity</classLabel>
<newAxiom>&apos;histone H3K56 methyltransferase activity&apos; SubClassOf &apos;histone lysine N-methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902940</classIRI>
<classLabel>positive regulation of intracellular calcium activated chloride channel activity</classLabel>
<deletedAxiom>&apos;positive regulation of intracellular calcium activated chloride channel activity&apos; SubClassOf &apos;positive regulation of inorganic anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902939</classIRI>
<classLabel>negative regulation of intracellular calcium activated chloride channel activity</classLabel>
<deletedAxiom>&apos;negative regulation of intracellular calcium activated chloride channel activity&apos; SubClassOf &apos;negative regulation of chloride transport&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of intracellular calcium activated chloride channel activity&apos; SubClassOf &apos;negative regulation of inorganic anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902938</classIRI>
<classLabel>regulation of intracellular calcium activated chloride channel activity</classLabel>
<deletedAxiom>&apos;regulation of intracellular calcium activated chloride channel activity&apos; SubClassOf &apos;regulation of inorganic anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of intracellular calcium activated chloride channel activity&apos; SubClassOf &apos;regulation of chloride transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032807</classIRI>
<classLabel>DNA ligase IV complex</classLabel>
<deletedAxiom>&apos;DNA ligase IV complex&apos; SubClassOf &apos;catalytic complex&apos;</deletedAxiom>
<newAxiom>&apos;DNA ligase IV complex&apos; SubClassOf &apos;nonhomologous end joining complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140617</classIRI>
<classLabel>transvection</classLabel>
<deletedAxiom>&apos;transvection&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Diptera&apos;</deletedAxiom>
<deletedAxiom>&apos;transvection&apos; SubClassOf &apos;in taxon&apos; only &apos;Diptera&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042246</classIRI>
<classLabel>tissue regeneration</classLabel>
<newAxiom>&apos;tissue regeneration&apos; SubClassOf &apos;in taxon&apos; some (not (&apos;Fungi&apos;))</newAxiom>
<newAxiom>&apos;tissue regeneration&apos; DisjointWith &apos;in taxon&apos; some &apos;Fungi&apos;</newAxiom>
<newAxiom>&apos;tissue regeneration&apos; SubClassOf not (&apos;in taxon&apos; some &apos;Fungi&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042174</classIRI>
<classLabel>negative regulation of sporulation resulting in formation of a cellular spore</classLabel>
<deletedAxiom>&apos;negative regulation of sporulation resulting in formation of a cellular spore&apos; SubClassOf &apos;negative regulation of cell differentiation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042173</classIRI>
<classLabel>regulation of sporulation resulting in formation of a cellular spore</classLabel>
<deletedAxiom>&apos;regulation of sporulation resulting in formation of a cellular spore&apos; SubClassOf &apos;regulation of cell differentiation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140576</classIRI>
<classLabel>ascorbate homeostasis</classLabel>
<deletedAxiom>&apos;ascorbate homeostasis&apos; SubClassOf &apos;anion homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;ascorbate homeostasis&apos; SubClassOf &apos;chemical homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017146</classIRI>
<classLabel>NMDA selective glutamate receptor complex</classLabel>
<deletedAxiom>&apos;NMDA selective glutamate receptor complex&apos; SubClassOf &apos;cation channel complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017145</classIRI>
<classLabel>stem cell division</classLabel>
<newAxiom>&apos;stem cell division&apos; SubClassOf not (&apos;in taxon&apos; some &apos;Fungi or Bacteria or Archaea&apos;)</newAxiom>
<newAxiom>&apos;stem cell division&apos; DisjointWith &apos;in taxon&apos; some &apos;Fungi or Bacteria or Archaea&apos;</newAxiom>
<newAxiom>&apos;stem cell division&apos; SubClassOf &apos;in taxon&apos; some (not (&apos;Fungi or Bacteria or Archaea&apos;))</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140484</classIRI>
<classLabel>5-aminolevulinic acid import across plasma membrane</classLabel>
<deletedAxiom>&apos;5-aminolevulinic acid import across plasma membrane&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;5-aminolevulinic acid import across plasma membrane&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140413</classIRI>
<classLabel>zinc:bicarbonate:selenite symporter activity</classLabel>
<deletedAxiom>&apos;zinc:bicarbonate:selenite symporter activity&apos; SubClassOf &apos;anion:cation symporter activity&apos;</deletedAxiom>
<newAxiom>&apos;zinc:bicarbonate:selenite symporter activity&apos; SubClassOf &apos;inorganic anion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140410</classIRI>
<classLabel>solute:bicarbonate symporter activity</classLabel>
<deletedAxiom>&apos;solute:bicarbonate symporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140407</classIRI>
<classLabel>L-alanine:proton antiporter activity</classLabel>
<deletedAxiom>&apos;L-alanine:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;L-alanine:proton antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;L-alanine:proton antiporter activity&apos; EquivalentTo &apos;solute:proton antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;L-alanine zwitterion&apos;)</deletedAxiom>
<newAxiom>&apos;L-alanine:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;L-alanine:proton antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has primary input&apos; some &apos;proton&apos;) and (&apos;has primary input&apos; some &apos;L-alanine zwitterion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140361</classIRI>
<classLabel>cyclic-GMP-AMP transmembrane import across plasma membrane</classLabel>
<deletedAxiom>&apos;cyclic-GMP-AMP transmembrane import across plasma membrane&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007531</classIRI>
<classLabel>mating type determination</classLabel>
<deletedAxiom>&apos;mating type determination&apos; SubClassOf &apos;cell fate commitment&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140323</classIRI>
<classLabel>solute:anion antiporter activity</classLabel>
<deletedAxiom>&apos;solute:anion antiporter activity&apos; SubClassOf &apos;has input&apos; some &apos;anion&apos;</deletedAxiom>
<deletedAxiom>&apos;solute:anion antiporter activity&apos; EquivalentTo &apos;antiporter activity&apos; and (&apos;has input&apos; some &apos;anion&apos;) and (&apos;has primary input&apos; some &apos;chemical entity&apos;)</deletedAxiom>
<deletedAxiom>&apos;solute:anion antiporter activity&apos; SubClassOf &apos;has primary input&apos; some &apos;chemical entity&apos;</deletedAxiom>
<deletedAxiom>&apos;solute:anion antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140300</classIRI>
<classLabel>serine import into mitochondrion</classLabel>
<deletedAxiom>&apos;serine import into mitochondrion&apos; SubClassOf &apos;anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;serine import into mitochondrion&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140215</classIRI>
<classLabel>regulation of D-aspartate import across plasma membrane</classLabel>
<deletedAxiom>&apos;regulation of D-aspartate import across plasma membrane&apos; SubClassOf &apos;regulation of anion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140217</classIRI>
<classLabel>positive regulation of D-aspartate import across plasma membrane</classLabel>
<deletedAxiom>&apos;positive regulation of D-aspartate import across plasma membrane&apos; SubClassOf &apos;positive regulation of anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of D-aspartate import across plasma membrane&apos; SubClassOf &apos;positive regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140216</classIRI>
<classLabel>negative regulation of D-aspartate import across plasma membrane</classLabel>
<deletedAxiom>&apos;negative regulation of D-aspartate import across plasma membrane&apos; SubClassOf &apos;negative regulation of anion transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of D-aspartate import across plasma membrane&apos; SubClassOf &apos;negative regulation of transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032412</classIRI>
<classLabel>regulation of ion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;regulation of ion transmembrane transporter activity&apos; SubClassOf &apos;regulation of ion transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071934</classIRI>
<classLabel>thiamine transmembrane transport</classLabel>
<deletedAxiom>&apos;thiamine transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140135</classIRI>
<classLabel>mechanosensitive cation channel activity</classLabel>
<deletedAxiom>&apos;mechanosensitive cation channel activity&apos; EquivalentTo &apos;mechanosensitive ion channel activity&apos; and (&apos;has primary input&apos; some &apos;inorganic cation&apos;)</deletedAxiom>
<newAxiom>&apos;mechanosensitive cation channel activity&apos; EquivalentTo &apos;mechanosensitive ion channel activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007368</classIRI>
<classLabel>determination of left/right symmetry</classLabel>
<newAxiom>&apos;determination of left/right symmetry&apos; SubClassOf &apos;part of&apos; some &apos;left/right pattern formation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032303</classIRI>
<classLabel>regulation of icosanoid secretion</classLabel>
<deletedAxiom>&apos;regulation of icosanoid secretion&apos; SubClassOf &apos;regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032305</classIRI>
<classLabel>positive regulation of icosanoid secretion</classLabel>
<deletedAxiom>&apos;positive regulation of icosanoid secretion&apos; SubClassOf &apos;positive regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032304</classIRI>
<classLabel>negative regulation of icosanoid secretion</classLabel>
<deletedAxiom>&apos;negative regulation of icosanoid secretion&apos; SubClassOf &apos;negative regulation of anion transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046976</classIRI>
<classLabel>histone H3K27 methyltransferase activity</classLabel>
<newAxiom>&apos;histone H3K27 methyltransferase activity&apos; SubClassOf &apos;histone lysine N-methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046975</classIRI>
<classLabel>histone H3K36 methyltransferase activity</classLabel>
<newAxiom>&apos;histone H3K36 methyltransferase activity&apos; SubClassOf &apos;histone lysine N-methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046974</classIRI>
<classLabel>histone H3K9 methyltransferase activity</classLabel>
<newAxiom>&apos;histone H3K9 methyltransferase activity&apos; SubClassOf &apos;histone lysine N-methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032329</classIRI>
<classLabel>serine transport</classLabel>
<deletedAxiom>&apos;serine transport&apos; SubClassOf &apos;cation transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032328</classIRI>
<classLabel>alanine transport</classLabel>
<deletedAxiom>&apos;alanine transport&apos; SubClassOf &apos;cation transport&apos;</deletedAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CL_4030028</classIRI>
<classLabel>glycinergic amacrine cell</classLabel>
<newAxiom>'glycinergic amacrine cell' EquivalentTo 'amacrine cell' and ('capable of' some 'glycine secretion, neurotransmission')</newAxiom>
<newAxiom>'glycinergic amacrine cell' SubClassOf 'amacrine cell'</newAxiom>
<newAxiom>'glycinergic amacrine cell' SubClassOf 'glycinergic neuron'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CL_4030027</classIRI>
<classLabel>GABAergic amacrine cell</classLabel>
<newAxiom>'GABAergic amacrine cell' EquivalentTo 'amacrine cell' and ('capable of' some 'gamma-aminobutyric acid secretion, neurotransmission')</newAxiom>
<newAxiom>'GABAergic amacrine cell' SubClassOf 'GABAergic interneuron'</newAxiom>
<newAxiom>'GABAergic amacrine cell' SubClassOf 'amacrine cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CL_4030012</classIRI>
<classLabel>kidney loop of Henle short descending thin limb epithelial cell</classLabel>
<newAxiom>'kidney loop of Henle short descending thin limb epithelial cell' SubClassOf 'kidney loop of Henle thin descending limb epithelial cell'</newAxiom>
<newAxiom>'kidney loop of Henle short descending thin limb epithelial cell' EquivalentTo 'epithelial cell' and ('part of' some 'short descending thin limb')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160066</classIRI>
<classLabel>interphase SIN signalling complex</classLabel>
<newAxiom>'interphase SIN signalling complex' SubClassOf 'SIN/MEN signalling complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160065</classIRI>
<classLabel>SIN/MEN signalling complex</classLabel>
<newAxiom>'SIN/MEN signalling complex' SubClassOf 'protein-containing complex'</newAxiom>
<newAxiom>'SIN/MEN signalling complex' SubClassOf 'part of' some 'outer plaque of mitotic spindle pole body'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160064</classIRI>
<classLabel>multi-pass translocon complex</classLabel>
<newAxiom>'multi-pass translocon complex' SubClassOf 'capable of part of' some 'multi-pass transmembrane protein insertion into ER membrane'</newAxiom>
<newAxiom>'multi-pass translocon complex' SubClassOf 'ER membrane insertion complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160063</classIRI>
<classLabel>multi-pass transmembrane protein insertion into ER membrane</classLabel>
<newAxiom>'multi-pass transmembrane protein insertion into ER membrane' SubClassOf 'protein insertion into ER membrane'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160062</classIRI>
<classLabel>cutin-based cuticle development</classLabel>
<newAxiom>'cutin-based cuticle development' SubClassOf 'anatomical structure development'</newAxiom>
<newAxiom>'cutin-based cuticle development' SubClassOf 'only_in_taxon' some 'Embryophyta'</newAxiom>
<newAxiom>'cutin-based cuticle development' SubClassOf 'in taxon' only 'Embryophyta'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160067</classIRI>
<classLabel>new spindle pole body SIN signalling complex</classLabel>
<newAxiom>'new spindle pole body SIN signalling complex' SubClassOf 'SIN/MEN signalling complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106439</classIRI>
<classLabel>L-lysine:L-arginine antiporter activity</classLabel>
<newAxiom>'L-lysine:L-arginine antiporter activity' EquivalentTo 'antiporter activity' and ('has primary input' some 'L-lysinium(1+)') and ('has primary input' some 'L-argininium(1+)')</newAxiom>
<newAxiom>'L-lysine:L-arginine antiporter activity' SubClassOf 'has_participant' some 'L-argininium(1+)'</newAxiom>
<newAxiom>'L-lysine:L-arginine antiporter activity' SubClassOf 'L-lysine transmembrane transporter activity'</newAxiom>
<newAxiom>'L-lysine:L-arginine antiporter activity' SubClassOf 'antiporter activity'</newAxiom>
<newAxiom>'L-lysine:L-arginine antiporter activity' SubClassOf 'L-arginine transmembrane transporter activity'</newAxiom>
<newAxiom>'L-lysine:L-arginine antiporter activity' SubClassOf 'has_participant' some 'L-lysinium(1+)'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CL_1001021</classIRI>
<classLabel>kidney loop of Henle descending limb epithelial cell</classLabel>
<newAxiom>'kidney loop of Henle descending limb epithelial cell' SubClassOf 'part of' some 'descending limb of loop of Henle'</newAxiom>
<newAxiom>'kidney loop of Henle descending limb epithelial cell' EquivalentTo 'kidney loop of Henle epithelial cell' and ('part of' some 'descending limb of loop of Henle')</newAxiom>
<newAxiom>'kidney loop of Henle descending limb epithelial cell' SubClassOf 'kidney loop of Henle epithelial cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CL_1001111</classIRI>
<classLabel>kidney loop of Henle thin descending limb epithelial cell</classLabel>
<newAxiom>'kidney loop of Henle thin descending limb epithelial cell' SubClassOf 'part of' some 'descending thin limb'</newAxiom>
<newAxiom>'kidney loop of Henle thin descending limb epithelial cell' SubClassOf 'kidney loop of Henle descending limb epithelial cell'</newAxiom>
<newAxiom>'kidney loop of Henle thin descending limb epithelial cell' EquivalentTo 'kidney loop of Henle descending limb epithelial cell' and ('part of' some 'descending thin limb')</newAxiom>
<newAxiom>'kidney loop of Henle thin descending limb epithelial cell' SubClassOf 'kidney epithelial cell'</newAxiom>
<newAxiom>'kidney loop of Henle thin descending limb epithelial cell' SubClassOf 'kidney outer medulla cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140959</classIRI>
<classLabel>obsolete base-pairing target-directed miRNA suppressor activity</classLabel>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140958</classIRI>
<classLabel>target-directed miRNA degradation</classLabel>
<newAxiom>'target-directed miRNA degradation' SubClassOf 'miRNA catabolic process'</newAxiom>
<newAxiom>'target-directed miRNA degradation' SubClassOf 'negative regulation of miRNA-mediated gene silencing'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>